Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23072
• Symbol:HECW1
• Description:HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1

DataSource: http://genomecrispr.dkfz.de/#!/results/HECW1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
43463727	43463750	7	+	26472758	Jiyoye	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-0.9147527133814888	[49]	[19]	-6	hSpCas9	negative selection	70030
43444402	43444425	7	+	26472758	Jiyoye	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	1.1997333016353968	[55]	[96]	7	hSpCas9	negative selection	70031
43311797	43311820	7	-	26472758	Jiyoye	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.30861154702228377	[105]	[98]	2	hSpCas9	negative selection	70032
43311815	43311838	7	+	26472758	Jiyoye	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.2551722880608238	[29]	[26]	2	hSpCas9	negative selection	70033
43311847	43311870	7	-	26472758	Jiyoye	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	1.3197125402555343	[16]	[31]	7	hSpCas9	negative selection	70034
43311932	43311955	7	-	26472758	Jiyoye	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	2.163070704206931	[52]	[178]	9	hSpCas9	negative selection	70035
43311971	43311994	7	-	26472758	Jiyoye	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	-0.6820919565912138	[199]	[93]	-5	hSpCas9	negative selection	70036
43312001	43312024	7	-	26472758	Jiyoye	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	1.9745438222122915	[54]	[162]	8	hSpCas9	negative selection	70037
43444283	43444306	7	+	26472758	Jiyoye	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	70038
43444361	43444384	7	+	26472758	Jiyoye	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.5553499130754639	[75]	[38]	-4	hSpCas9	negative selection	70039
43463727	43463750	7	+	26472758	KBM7	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	0.0045494005932453785	[170,203]	[95,83]	0	hSpCas9	negative selection	261148
43444402	43444425	7	+	26472758	KBM7	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	0.08827801697359841	[358,503]	[145,286]	0	hSpCas9	negative selection	261149
43311797	43311820	7	-	26472758	KBM7	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	-0.034146183956654454	[566,427]	[182,264]	0	hSpCas9	negative selection	261150
43311815	43311838	7	+	26472758	KBM7	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.3453381750684892	[170,109]	[82,81]	3	hSpCas9	negative selection	261151
43311847	43311870	7	-	26472758	KBM7	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.060094093526892545	[182,112]	[103,30]	0	hSpCas9	negative selection	261152
43311932	43311955	7	-	26472758	KBM7	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	-0.19242524366106795	[555,534]	[307,150]	-2	hSpCas9	negative selection	261153
43311971	43311994	7	-	26472758	KBM7	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	-0.5671892459508795	[684,531]	[180,200]	-5	hSpCas9	negative selection	261154
43312001	43312024	7	-	26472758	KBM7	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.611357077420708	[610,511]	[445,361]	6	hSpCas9	negative selection	261155
43444283	43444306	7	+	26472758	KBM7	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	1.2656721485717222	[91,65]	[111,66]	9	hSpCas9	negative selection	261156
43444361	43444384	7	+	26472758	KBM7	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	0.1877147491587745	[222,183]	[118,98]	2	hSpCas9	negative selection	261157
43463727	43463750	7	+	26472758	Raji	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	0.0050218177439216305	[72]	[16]	0	hSpCas9	negative selection	452266
43444402	43444425	7	+	26472758	Raji	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	0.252023240405163	[274]	[75]	2	hSpCas9	negative selection	452267
43311797	43311820	7	-	26472758	Raji	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.7041922789428641	[282]	[106]	6	hSpCas9	negative selection	452268
43311815	43311838	7	+	26472758	Raji	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	-0.7670855825425416	[65]	[8]	-5	hSpCas9	negative selection	452269
43311847	43311870	7	-	26472758	Raji	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.4775789653475566	[71]	[11]	-4	hSpCas9	negative selection	452270
43311932	43311955	7	-	26472758	Raji	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.535841550414765	[213]	[71]	5	hSpCas9	negative selection	452271
43311971	43311994	7	-	26472758	Raji	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	-0.3991523183907404	[357]	[62]	-3	hSpCas9	negative selection	452272
43312001	43312024	7	-	26472758	Raji	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	-1.0107978909747146	[355]	[40]	-6	hSpCas9	negative selection	452273
43444283	43444306	7	+	26472758	Raji	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	1.1073835353735995	[63]	[31]	8	hSpCas9	negative selection	452274
43444361	43444384	7	+	26472758	Raji	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.5872034565220547	[122]	[18]	-5	hSpCas9	negative selection	452275
43463727	43463750	7	+	26472758	K562	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-0.7111871529750999	[127]	[65]	-4	hSpCas9	negative selection	643384
43444402	43444425	7	+	26472758	K562	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.5405683813627027	[447]	[259]	-3	hSpCas9	negative selection	643385
43311797	43311820	7	-	26472758	K562	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.9266784297425181	[343]	[551]	7	hSpCas9	negative selection	643386
43311815	43311838	7	+	26472758	K562	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	1.324418049731667	[113]	[240]	9	hSpCas9	negative selection	643387
43311847	43311870	7	-	26472758	K562	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.7336808119670177	[160]	[225]	6	hSpCas9	negative selection	643388
43311932	43311955	7	-	26472758	K562	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.16169380542277068	[322]	[304]	1	hSpCas9	negative selection	643389
43311971	43311994	7	-	26472758	K562	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	-0.2132936911158983	[628]	[457]	-1	hSpCas9	negative selection	643390
43312001	43312024	7	-	26472758	K562	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.6632478061076648	[379]	[507]	5	hSpCas9	negative selection	643391
43444283	43444306	7	+	26472758	K562	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	1.1901983366685602	[121]	[234]	8	hSpCas9	negative selection	643392
43444361	43444384	7	+	26472758	K562	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-2.7190553963084394	[155]	[19]	-8	hSpCas9	negative selection	643393
43311925	43311948	7	-	26627737	DLD1	viability	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.017230493151650705	[2266]	[888,493,752]	0	hSpCas9	negative selection	836444
43396835	43396858	7	+	26627737	DLD1	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.8322405183624297	[138]	[113,94,30]	7	hSpCas9	negative selection	836445
43407661	43407684	7	+	26627737	DLD1	viability	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.7702897472749748	[875]	[171,240,83]	-6	hSpCas9	negative selection	836446
43438019	43438042	7	-	26627737	DLD1	viability	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	-0.16040035055114732	[1604]	[404,623,341]	-2	hSpCas9	negative selection	836447
43442540	43442563	7	+	26627737	DLD1	viability	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.21219700310719414	[697]	[256,305,204]	2	hSpCas9	negative selection	836448
43311925	43311948	7	-	26627737	GBM cells	viability after 5 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.09005536223769384	[719]	[410,410]	1	hSpCas9	negative selection	918759
43396835	43396858	7	+	26627737	GBM cells	viability after 5 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.47459856201883077	[103]	[73,80]	7	hSpCas9	negative selection	918760
43407661	43407684	7	+	26627737	GBM cells	viability after 5 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	0.21004256892052459	[294]	[170,194]	3	hSpCas9	negative selection	918761
43438019	43438042	7	-	26627737	GBM cells	viability after 5 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.25639148501924136	[472]	[304,300]	4	hSpCas9	negative selection	918762
43442540	43442563	7	+	26627737	GBM cells	viability after 5 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.4774501064474088	[224]	[165,169]	7	hSpCas9	negative selection	918763
43311925	43311948	7	-	26627737	GBM cells	viability after 13 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.13389646135545452	[719]	[560,320]	1	hSpCas9	negative selection	1001074
43396835	43396858	7	+	26627737	GBM cells	viability after 13 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.6176400035745236	[103]	[74,95]	7	hSpCas9	negative selection	1001075
43407661	43407684	7	+	26627737	GBM cells	viability after 13 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.7357385937754122	[294]	[126,70]	-7	hSpCas9	negative selection	1001076
43438019	43438042	7	-	26627737	GBM cells	viability after 13 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.5937199193204611	[472]	[442,341]	7	hSpCas9	negative selection	1001077
43442540	43442563	7	+	26627737	GBM cells	viability after 13 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.01641377942858599	[224]	[139,104]	0	hSpCas9	negative selection	1001078
43311925	43311948	7	-	26627737	GBM cells	viability after 21 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.05558215643985642	[719]	[390,362]	0	hSpCas9	negative selection	1083389
43396835	43396858	7	+	26627737	GBM cells	viability after 21 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	1.4278265512276092	[103]	[139,162]	9	hSpCas9	negative selection	1083390
43407661	43407684	7	+	26627737	GBM cells	viability after 21 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-1.4925731776716424	[294]	[57,55]	-8	hSpCas9	negative selection	1083391
43438019	43438042	7	-	26627737	GBM cells	viability after 21 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.75874505641621	[472]	[462,408]	7	hSpCas9	negative selection	1083392
43442540	43442563	7	+	26627737	GBM cells	viability after 21 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.19568089469364017	[224]	[112,100]	-2	hSpCas9	negative selection	1083393
43311925	43311948	7	-	26627737	RPE1	viability after 9 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.48686140617182017	[2665]	[1125,1225]	3	hSpCas9	negative selection	1165704
43396835	43396858	7	+	26627737	RPE1	viability after 9 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.8841936349289304	[223]	[66,209]	5	hSpCas9	negative selection	1165705
43407661	43407684	7	+	26627737	RPE1	viability after 9 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.7022386202472926	[1400]	[307,219]	-5	hSpCas9	negative selection	1165706
43438019	43438042	7	-	26627737	RPE1	viability after 9 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.6629837432864791	[1869]	[967,873]	4	hSpCas9	negative selection	1165707
43442540	43442563	7	+	26627737	RPE1	viability after 9 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	1.5723645446377397	[326]	[341,255]	8	hSpCas9	negative selection	1165708
43311925	43311948	7	-	26627737	RPE1	viability after 12 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.4443590523983738	[2665]	[1267,663]	3	hSpCas9	negative selection	1248019
43396835	43396858	7	+	26627737	RPE1	viability after 12 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	1.1554607706990754	[223]	[118,149]	7	hSpCas9	negative selection	1248020
43407661	43407684	7	+	26627737	RPE1	viability after 12 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.7432649253077981	[1400]	[253,193]	-5	hSpCas9	negative selection	1248021
43438019	43438042	7	-	26627737	RPE1	viability after 12 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	1.0155677793473121	[1869]	[1141,881]	6	hSpCas9	negative selection	1248022
43442540	43442563	7	+	26627737	RPE1	viability after 12 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.8043879421028639	[326]	[184,119]	5	hSpCas9	negative selection	1248023
43311925	43311948	7	-	26627737	RPE1	viability after 15 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.14472949309344973	[2665]	[904,764]	1	hSpCas9	negative selection	1330334
43396835	43396858	7	+	26627737	RPE1	viability after 15 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.6322644283438912	[223]	[57,136]	4	hSpCas9	negative selection	1330335
43407661	43407684	7	+	26627737	RPE1	viability after 15 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.5700654050754448	[1400]	[325,209]	-4	hSpCas9	negative selection	1330336
43438019	43438042	7	-	26627737	RPE1	viability after 15 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	1.209425884052367	[1869]	[1574,883]	7	hSpCas9	negative selection	1330337
43442540	43442563	7	+	26627737	RPE1	viability after 15 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	1.6178663805257343	[326]	[457,115]	8	hSpCas9	negative selection	1330338
43311925	43311948	7	-	26627737	RPE1	viability after 18 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.6917486454191002	[2665]	[1252,1064]	4	hSpCas9	negative selection	1412649
43396835	43396858	7	+	26627737	RPE1	viability after 18 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	1.0017980248388167	[223]	[107,134]	6	hSpCas9	negative selection	1412650
43407661	43407684	7	+	26627737	RPE1	viability after 18 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.32643406481677906	[1400]	[345,253]	-2	hSpCas9	negative selection	1412651
43438019	43438042	7	-	26627737	RPE1	viability after 18 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.6723395497593043	[1869]	[927,671]	4	hSpCas9	negative selection	1412652
43442540	43442563	7	+	26627737	RPE1	viability after 18 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.4956169182359649	[326]	[194,48]	3	hSpCas9	negative selection	1412653
43311925	43311948	7	-	26627737	HeLa	viability after 8 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.3382612755307062	[1248]	[501,882,638]	3	hSpCas9	negative selection	1494964
43396835	43396858	7	+	26627737	HeLa	viability after 8 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.12475363580472543	[225]	[109,45,116]	-1	hSpCas9	negative selection	1494965
43407661	43407684	7	+	26627737	HeLa	viability after 8 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.1176932047917767	[707]	[211,280,338]	-1	hSpCas9	negative selection	1494966
43438019	43438042	7	-	26627737	HeLa	viability after 8 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	-0.7875367577424839	[1404]	[367,393,306]	-7	hSpCas9	negative selection	1494967
43442540	43442563	7	+	26627737	HeLa	viability after 8 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.24405400160734825	[592]	[373,199,120]	-2	hSpCas9	negative selection	1494968
43311925	43311948	7	-	26627737	HeLa	viability after 12 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.5868422257536852	[1248]	[617,597,1123]	5	hSpCas9	negative selection	1577279
43396835	43396858	7	+	26627737	HeLa	viability after 12 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-1.0863521123317592	[225]	[47,72,7]	-7	hSpCas9	negative selection	1577280
43407661	43407684	7	+	26627737	HeLa	viability after 12 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	0.1152334008494682	[707]	[243,322,380]	1	hSpCas9	negative selection	1577281
43438019	43438042	7	-	26627737	HeLa	viability after 12 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	-0.27006033911570815	[1404]	[377,646,398]	-2	hSpCas9	negative selection	1577282
43442540	43442563	7	+	26627737	HeLa	viability after 12 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.10541902165179934	[592]	[183,294,195]	-1	hSpCas9	negative selection	1577283
43311925	43311948	7	-	26627737	HeLa	viability after 15 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.6015299005662811	[1248]	[864,523,936]	5	hSpCas9	negative selection	1659594
43396835	43396858	7	+	26627737	HeLa	viability after 15 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.36166041308151475	[225]	[142,72,139]	3	hSpCas9	negative selection	1659595
43407661	43407684	7	+	26627737	HeLa	viability after 15 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.8776481091519646	[707]	[58,181,236]	-6	hSpCas9	negative selection	1659596
43438019	43438042	7	-	26627737	HeLa	viability after 15 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	-0.43543374205944296	[1404]	[342,502,423]	-4	hSpCas9	negative selection	1659597
43442540	43442563	7	+	26627737	HeLa	viability after 15 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.14026590999534544	[592]	[295,166,190]	-1	hSpCas9	negative selection	1659598
43311925	43311948	7	-	26627737	HeLa	viability after 18 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.625653330580836	[1248]	[587,455,936]	5	hSpCas9	negative selection	1741909
43396835	43396858	7	+	26627737	HeLa	viability after 18 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.34458845021389367	[225]	[91,61,139]	3	hSpCas9	negative selection	1741910
43407661	43407684	7	+	26627737	HeLa	viability after 18 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.8707974221710745	[707]	[35,156,236]	-6	hSpCas9	negative selection	1741911
43438019	43438042	7	-	26627737	HeLa	viability after 18 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	-0.4269354882455656	[1404]	[236,413,423]	-4	hSpCas9	negative selection	1741912
43442540	43442563	7	+	26627737	HeLa	viability after 18 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.14511824652459915	[592]	[194,140,190]	-1	hSpCas9	negative selection	1741913
43311925	43311948	7	-	26627737	HCT116	viability after 6 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	1.4679233844475983	[1714]	[574,839]	7	hSpCas9	negative selection	1824224
43396835	43396858	7	+	26627737	HCT116	viability after 6 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.7694661100792315	[67]	[14,19]	4	hSpCas9	negative selection	1824225
43407661	43407684	7	+	26627737	HCT116	viability after 6 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	0.8853609869905023	[879]	[426,160]	5	hSpCas9	negative selection	1824226
43438019	43438042	7	-	26627737	HCT116	viability after 6 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	1.205257019904923	[839]	[444,226]	6	hSpCas9	negative selection	1824227
43442540	43442563	7	+	26627737	HCT116	viability after 6 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.8807344390195103	[913]	[426,174]	5	hSpCas9	negative selection	1824228
43311925	43311948	7	-	26627737	HCT116	viability after 8 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.25705047148687155	[948]	[632,626,614]	3	hSpCas9	negative selection	1906539
43396835	43396858	7	+	26627737	HCT116	viability after 8 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.6097354681409131	[61]	[50,21,82]	6	hSpCas9	negative selection	1906540
43407661	43407684	7	+	26627737	HCT116	viability after 8 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	1.2772040756483158	[223]	[297,345,253]	9	hSpCas9	negative selection	1906541
43438019	43438042	7	-	26627737	HCT116	viability after 8 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.5652397986526306	[381]	[390,251,292]	5	hSpCas9	negative selection	1906542
43442540	43442563	7	+	26627737	HCT116	viability after 8 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.04594437994231482	[400]	[94,249,293]	0	hSpCas9	negative selection	1906543
43311925	43311948	7	-	26627737	HCT116	viability after 9 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.6943442226444876	[1714]	[697,774]	5	hSpCas9	negative selection	1988854
43396835	43396858	7	+	26627737	HCT116	viability after 9 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	1.5227078852427773	[67]	[102,11]	8	hSpCas9	negative selection	1988855
43407661	43407684	7	+	26627737	HCT116	viability after 9 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	0.9116208711699997	[879]	[498,396]	6	hSpCas9	negative selection	1988856
43438019	43438042	7	-	26627737	HCT116	viability after 9 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.4609869987437766	[839]	[377,253]	3	hSpCas9	negative selection	1988857
43442540	43442563	7	+	26627737	HCT116	viability after 9 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.7464527775869835	[913]	[347,457]	5	hSpCas9	negative selection	1988858
43311925	43311948	7	-	26627737	HCT116	viability after 12 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.7863034224754537	[948]	[754,669,1159]	7	hSpCas9	negative selection	2071169
43396835	43396858	7	+	26627737	HCT116	viability after 12 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	1.2247452343322607	[61]	[10,68,153]	8	hSpCas9	negative selection	2071170
43407661	43407684	7	+	26627737	HCT116	viability after 12 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	1.1069793690199454	[223]	[205,300,258]	8	hSpCas9	negative selection	2071171
43438019	43438042	7	-	26627737	HCT116	viability after 12 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	1.1624174873078732	[381]	[577,418,338]	8	hSpCas9	negative selection	2071172
43442540	43442563	7	+	26627737	HCT116	viability after 12 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.15039076926930184	[400]	[178,165,224]	-1	hSpCas9	negative selection	2071173
43311925	43311948	7	-	26627737	HCT116	viability after 15 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.3662928201445188	[948]	[659,621,818]	3	hSpCas9	negative selection	2153484
43396835	43396858	7	+	26627737	HCT116	viability after 15 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.9892367391445289	[61]	[19,41,142]	8	hSpCas9	negative selection	2153485
43407661	43407684	7	+	26627737	HCT116	viability after 15 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	1.2029908083476806	[223]	[425,242,235]	8	hSpCas9	negative selection	2153486
43438019	43438042	7	-	26627737	HCT116	viability after 15 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	1.0427555718424673	[381]	[557,376,433]	8	hSpCas9	negative selection	2153487
43442540	43442563	7	+	26627737	HCT116	viability after 15 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.17303413587123276	[400]	[177,260,170]	-2	hSpCas9	negative selection	2153488
43311925	43311948	7	-	26627737	HCT116	viability after 18 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.3743471896512982	[948]	[663,421,714]	3	hSpCas9	negative selection	2235799
43396835	43396858	7	+	26627737	HCT116	viability after 18 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.12776949802087278	[61]	[3,20,75]	1	hSpCas9	negative selection	2235800
43407661	43407684	7	+	26627737	HCT116	viability after 18 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	1.1486328418921266	[223]	[331,178,211]	8	hSpCas9	negative selection	2235801
43438019	43438042	7	-	26627737	HCT116	viability after 18 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	1.134323330090075	[381]	[362,355,504]	8	hSpCas9	negative selection	2235802
43442540	43442563	7	+	26627737	HCT116	viability after 18 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.14760299636698765	[400]	[230,177,112]	-1	hSpCas9	negative selection	2235803
43311758	43311781	7	+	24336569	HL60	viability	CACAGAATCTGTACCAGAACAGG	HECW1	ENSG00000002746	-0.19934781575592764	[324]	[598]	-2	hSpCas9	negative selection	2269296
43311789	43311812	7	-	24336569	HL60	viability	AAGGAGACGCCATGGCGGCCAGG	HECW1	ENSG00000002746	-0.06660614190178314	[482]	[975]	0	hSpCas9	negative selection	2269297
43311815	43311838	7	+	24336569	HL60	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.24918121135957488	[461]	[1161]	2	hSpCas9	negative selection	2269298
43311821	43311844	7	-	24336569	HL60	viability	CTTGCACCGGCGTCGGCTCTGGG	HECW1	ENSG00000002746	-0.33743511394012127	[488]	[818]	-3	hSpCas9	negative selection	2269299
43311828	43311851	7	-	24336569	HL60	viability	GCGGCTCCTTGCACCGGCGTCGG	HECW1	ENSG00000002746	0.7299797094965864	[150]	[529]	6	hSpCas9	negative selection	2269300
43311834	43311857	7	-	24336569	HL60	viability	ATCGGAGCGGCTCCTTGCACCGG	HECW1	ENSG00000002746	-0.5612072892955555	[379]	[544]	-5	hSpCas9	negative selection	2269301
43311847	43311870	7	-	24336569	HL60	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	1.3172741803472852	[394]	[2082]	8	hSpCas9	negative selection	2269302
43311868	43311891	7	-	24336569	HL60	viability	TCCATGTTGTGGAACTGGTCGGG	HECW1	ENSG00000002746	-0.25495525308064804	[961]	[1705]	-2	hSpCas9	negative selection	2269303
43311758	43311781	7	+	24336569	KBM7	viability	CACAGAATCTGTACCAGAACAGG	HECW1	ENSG00000002746	0.8448520010939831	[167]	[822]	7	hSpCas9	negative selection	2336473
43311789	43311812	7	-	24336569	KBM7	viability	AAGGAGACGCCATGGCGGCCAGG	HECW1	ENSG00000002746	0.3827673681349506	[497]	[1770]	3	hSpCas9	negative selection	2336474
43311815	43311838	7	+	24336569	KBM7	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	-0.6559542174445657	[605]	[1048]	-5	hSpCas9	negative selection	2336475
43311821	43311844	7	-	24336569	KBM7	viability	CTTGCACCGGCGTCGGCTCTGGG	HECW1	ENSG00000002746	1.136364091808521	[235]	[1414]	8	hSpCas9	negative selection	2336476
43311828	43311851	7	-	24336569	KBM7	viability	GCGGCTCCTTGCACCGGCGTCGG	HECW1	ENSG00000002746	0.4538049227530925	[139]	[522]	4	hSpCas9	negative selection	2336477
43311834	43311857	7	-	24336569	KBM7	viability	ATCGGAGCGGCTCCTTGCACCGG	HECW1	ENSG00000002746	-0.49306196634289073	[289]	[561]	-4	hSpCas9	negative selection	2336478
43311847	43311870	7	-	24336569	KBM7	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.17722356870406475	[499]	[1541]	1	hSpCas9	negative selection	2336479
43311868	43311891	7	-	24336569	KBM7	viability	TCCATGTTGTGGAACTGGTCGGG	HECW1	ENSG00000002746	0.8229358256457993	[536]	[2590]	7	hSpCas9	negative selection	2336480
43169716	43169739	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGTCTCGCTGTCGCCCAGGCTAG	HECW1	ENSG00000002746	0.8346262078071658	[10,1]	[2,1]	3	dCas9-VP64	positive selection	2416318
43305674	43305697	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCACCTCCCGGG	HECW1	ENSG00000002746	-1.4516426362223873	[480,182]	[29,20]	-8	dCas9-VP64	positive selection	2427048
43287527	43287550	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTCACTATATTGCCCAGG	HECW1	ENSG00000002746	2.346297348584061	[172,220]	[56,398]	7	dCas9-VP64	positive selection	2428395
43213720	43213743	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACTGCGCCCAG	HECW1	ENSG00000002746	-0.04533809600197003	[16,0]	[1,0]	0	dCas9-VP64	positive selection	2431184
43331116	43331139	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGGGGAGGGATAGCATCAG	HECW1	ENSG00000002746	-0.2768784612498725	[39,10]	[6,1]	-1	dCas9-VP64	positive selection	2437426
43371943	43371966	7	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCTCAGCTACTAGG	HECW1	ENSG00000002746	-0.32009396436001514	[73,465]	[65,28]	-1	dCas9-VP64	positive selection	2454649
43228239	43228262	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTTTGGGAGGCCAAGGCAGGGG	HECW1	ENSG00000002746	2.0119762381202047	[93,200]	[9,263]	7	dCas9-VP64	positive selection	2462430
43530518	43530541	7	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGATGGATGGATGGATGGAAAG	HECW1	ENSG00000002746	2.7644531499590617	[51,2]	[77,0]	8	dCas9-VP64	positive selection	2471243
43169716	43169739	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGTCTCGCTGTCGCCCAGGCTAG	HECW1	ENSG00000002746	-1.711674582430177	[43,184]	[8,12]	-9	dCas9-VP64	positive selection	2511573
43305674	43305697	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCACCTCCCGGG	HECW1	ENSG00000002746	1.047613524569726	[257,163]	[245,45]	6	dCas9-VP64	positive selection	2522303
43287527	43287550	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTCACTATATTGCCCAGG	HECW1	ENSG00000002746	-0.41126224133599143	[350,385]	[99,80]	-4	dCas9-VP64	positive selection	2523650
43213720	43213743	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACTGCGCCCAG	HECW1	ENSG00000002746	-1.0099528387584376	[28,142]	[9,15]	-8	dCas9-VP64	positive selection	2526439
43331116	43331139	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGGGGAGGGATAGCATCAG	HECW1	ENSG00000002746	2.3864657481970033	[28,33]	[18,86]	9	dCas9-VP64	positive selection	2532681
43371943	43371966	7	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCTCAGCTACTAGG	HECW1	ENSG00000002746	-0.35714226545986627	[161,80]	[51,10]	-4	dCas9-VP64	positive selection	2549904
43228239	43228262	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTTTGGGAGGCCAAGGCAGGGG	HECW1	ENSG00000002746	-0.4547686614086857	[146,265]	[55,41]	-5	dCas9-VP64	positive selection	2557685
43530518	43530541	7	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGATGGATGGATGGATGGAAAG	HECW1	ENSG00000002746	-0.745179068402318	[185,151]	[42,22]	-7	dCas9-VP64	positive selection	2566498
43311966	43311989	7	-	27260157	DLD1	viability	TGCTGACCATGAGCGTGGAGCGG	HECW1	ENSG00000002746	0.406222513420814	[]	[]	4	hSpCas9	negative selection	2583087
43311834	43311857	7	-	27260157	DLD1	viability	ATCGGAGCGGCTCCTTGCACCGG	HECW1	ENSG00000002746	-1.26126878008971	[]	[]	-7	hSpCas9	negative selection	2604184
43311985	43312008	7	+	27260157	DLD1	viability	AGCAGCTCCTACTATTCCATCGG	HECW1	ENSG00000002746	0.56911292966538	[]	[]	8	hSpCas9	negative selection	2604237
43311828	43311851	7	-	27260157	DLD1	viability	GCGGCTCCTTGCACCGGCGTCGG	HECW1	ENSG00000002746	-0.0920958963875651	[]	[]	0	hSpCas9	negative selection	2606528
43311868	43311891	7	-	27260157	DLD1	viability	TCCATGTTGTGGAACTGGTCGGG	HECW1	ENSG00000002746	-0.626052941125993	[]	[]	-5	hSpCas9	negative selection	2609914
43311925	43311948	7	-	27260157	DLD1	viability	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-2.55834650342359	[]	[]	-9	hSpCas9	negative selection	2611826
43320717	43320740	7	+	27260157	DLD1	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.360288798007903	[]	[]	4	hSpCas9	negative selection	2617327
43438017	43438040	7	+	27260157	DLD1	viability	GTCCTTGCCCACTGACGTGCTGG	HECW1	ENSG00000002746	-0.0780756719185035	[]	[]	0	hSpCas9	negative selection	2618578
43311815	43311838	7	+	27260157	DLD1	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	-0.474007412532995	[]	[]	-4	hSpCas9	negative selection	2618834
43311996	43312019	7	+	27260157	DLD1	viability	CTATTCCATCGGGCACTCTCAGG	HECW1	ENSG00000002746	0.215960448329732	[]	[]	3	hSpCas9	negative selection	2619261
43311847	43311870	7	-	27260157	DLD1	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-1.65142713892026	[]	[]	-8	hSpCas9	negative selection	2619612
43311821	43311844	7	-	27260157	DLD1	viability	CTTGCACCGGCGTCGGCTCTGGG	HECW1	ENSG00000002746	0.870782077352689	[]	[]	9	hSpCas9	negative selection	2620746
43311789	43311812	7	-	27260157	DLD1	viability	AAGGAGACGCCATGGCGGCCAGG	HECW1	ENSG00000002746	0.901245995540732	[]	[]	9	hSpCas9	negative selection	2622674
43312013	43312036	7	+	27260157	DLD1	viability	CTCAGGACCTGGTCATCCACTGG	HECW1	ENSG00000002746	0.992282822492473	[]	[]	9	hSpCas9	negative selection	2623930
43311758	43311781	7	+	27260157	DLD1	viability	CACAGAATCTGTACCAGAACAGG	HECW1	ENSG00000002746	0.795410463436465	[]	[]	9	hSpCas9	negative selection	2641661
43407688	43407711	7	-	27260157	DLD1	viability	CACGGTGTTGCCTATGATCTTGG	HECW1	ENSG00000002746	0.809702839225457	[]	[]	9	hSpCas9	negative selection	2645095
43311867	43311890	7	-	27260157	DLD1	viability	CCATGTTGTGGAACTGGTCGGGG	HECW1	ENSG00000002746	0.478231306884946	[]	[]	8	hSpCas9	negative selection	2648205
43320699	43320722	7	-	27260157	DLD1	viability	CATCGATCTTCCAGATGATCTGG	HECW1	ENSG00000002746	0.462955253699649	[]	[]	8	hSpCas9	negative selection	2649508
43311966	43311989	7	-	27260157	HT1080	viability	TGCTGACCATGAGCGTGGAGCGG	HECW1	ENSG00000002746	1.19168831322281	[]	[]	8	hSpCas9	negative selection	2659217
43311834	43311857	7	-	27260157	HT1080	viability	ATCGGAGCGGCTCCTTGCACCGG	HECW1	ENSG00000002746	-0.725079962769618	[]	[]	-8	hSpCas9	negative selection	2680314
43311985	43312008	7	+	27260157	HT1080	viability	AGCAGCTCCTACTATTCCATCGG	HECW1	ENSG00000002746	0.257848787586554	[]	[]	2	hSpCas9	negative selection	2680367
43311828	43311851	7	-	27260157	HT1080	viability	GCGGCTCCTTGCACCGGCGTCGG	HECW1	ENSG00000002746	-0.694450308686587	[]	[]	-8	hSpCas9	negative selection	2682658
43311868	43311891	7	-	27260157	HT1080	viability	TCCATGTTGTGGAACTGGTCGGG	HECW1	ENSG00000002746	-0.242374564066746	[]	[]	0	hSpCas9	negative selection	2686044
43311925	43311948	7	-	27260157	HT1080	viability	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-1.43850656113269	[]	[]	-9	hSpCas9	negative selection	2687956
43320717	43320740	7	+	27260157	HT1080	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.770881570265035	[]	[]	6	hSpCas9	negative selection	2693457
43438017	43438040	7	+	27260157	HT1080	viability	GTCCTTGCCCACTGACGTGCTGG	HECW1	ENSG00000002746	0.370117444997457	[]	[]	3	hSpCas9	negative selection	2694708
43311815	43311838	7	+	27260157	HT1080	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.952652420912545	[]	[]	7	hSpCas9	negative selection	2694964
43311996	43312019	7	+	27260157	HT1080	viability	CTATTCCATCGGGCACTCTCAGG	HECW1	ENSG00000002746	0.150841723687277	[]	[]	1	hSpCas9	negative selection	2695391
43311847	43311870	7	-	27260157	HT1080	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-1.17890171411039	[]	[]	-8	hSpCas9	negative selection	2695742
43311821	43311844	7	-	27260157	HT1080	viability	CTTGCACCGGCGTCGGCTCTGGG	HECW1	ENSG00000002746	-0.209401008571336	[]	[]	0	hSpCas9	negative selection	2696876
43311789	43311812	7	-	27260157	HT1080	viability	AAGGAGACGCCATGGCGGCCAGG	HECW1	ENSG00000002746	1.83295866904392	[]	[]	9	hSpCas9	negative selection	2698804
43312013	43312036	7	+	27260157	HT1080	viability	CTCAGGACCTGGTCATCCACTGG	HECW1	ENSG00000002746	0.850550456555228	[]	[]	7	hSpCas9	negative selection	2700060
43311758	43311781	7	+	27260157	HT1080	viability	CACAGAATCTGTACCAGAACAGG	HECW1	ENSG00000002746	0.775836432878932	[]	[]	6	hSpCas9	negative selection	2717791
43407688	43407711	7	-	27260157	HT1080	viability	CACGGTGTTGCCTATGATCTTGG	HECW1	ENSG00000002746	-0.262988259432685	[]	[]	0	hSpCas9	negative selection	2721225
43311867	43311890	7	-	27260157	HT1080	viability	CCATGTTGTGGAACTGGTCGGGG	HECW1	ENSG00000002746	-0.498623021625239	[]	[]	-7	hSpCas9	negative selection	2724335
43320699	43320722	7	-	27260157	HT1080	viability	CATCGATCTTCCAGATGATCTGG	HECW1	ENSG00000002746	1.40808878155307	[]	[]	9	hSpCas9	negative selection	2725638
43311966	43311989	7	-	27260157	MKN45	viability	TGCTGACCATGAGCGTGGAGCGG	HECW1	ENSG00000002746	1.29741088352446	[]	[]	9	hSpCas9	negative selection	2735347
43311834	43311857	7	-	27260157	MKN45	viability	ATCGGAGCGGCTCCTTGCACCGG	HECW1	ENSG00000002746	-1.92372521406935	[]	[]	-9	hSpCas9	negative selection	2756444
43311985	43312008	7	+	27260157	MKN45	viability	AGCAGCTCCTACTATTCCATCGG	HECW1	ENSG00000002746	-1.3526814376722	[]	[]	-8	hSpCas9	negative selection	2756497
43311828	43311851	7	-	27260157	MKN45	viability	GCGGCTCCTTGCACCGGCGTCGG	HECW1	ENSG00000002746	-0.477470436367529	[]	[]	-6	hSpCas9	negative selection	2758788
43311868	43311891	7	-	27260157	MKN45	viability	TCCATGTTGTGGAACTGGTCGGG	HECW1	ENSG00000002746	-0.491419085201762	[]	[]	-6	hSpCas9	negative selection	2762174
43311925	43311948	7	-	27260157	MKN45	viability	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.435517650586253	[]	[]	-6	hSpCas9	negative selection	2764086
43320717	43320740	7	+	27260157	MKN45	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.490260503206317	[]	[]	-6	hSpCas9	negative selection	2769587
43438017	43438040	7	+	27260157	MKN45	viability	GTCCTTGCCCACTGACGTGCTGG	HECW1	ENSG00000002746	0.0637588753876437	[]	[]	0	hSpCas9	negative selection	2770838
43311815	43311838	7	+	27260157	MKN45	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.24641567298496	[]	[]	5	hSpCas9	negative selection	2771094
43311996	43312019	7	+	27260157	MKN45	viability	CTATTCCATCGGGCACTCTCAGG	HECW1	ENSG00000002746	-1.01786574457851	[]	[]	-8	hSpCas9	negative selection	2771521
43311847	43311870	7	-	27260157	MKN45	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.944807462495319	[]	[]	-7	hSpCas9	negative selection	2771872
43311821	43311844	7	-	27260157	MKN45	viability	CTTGCACCGGCGTCGGCTCTGGG	HECW1	ENSG00000002746	0.132137287957658	[]	[]	4	hSpCas9	negative selection	2773006
43311789	43311812	7	-	27260157	MKN45	viability	AAGGAGACGCCATGGCGGCCAGG	HECW1	ENSG00000002746	1.70793913399607	[]	[]	9	hSpCas9	negative selection	2774934
43312013	43312036	7	+	27260157	MKN45	viability	CTCAGGACCTGGTCATCCACTGG	HECW1	ENSG00000002746	0.905990000641974	[]	[]	8	hSpCas9	negative selection	2776190
43311758	43311781	7	+	27260157	MKN45	viability	CACAGAATCTGTACCAGAACAGG	HECW1	ENSG00000002746	0.685482681170581	[]	[]	7	hSpCas9	negative selection	2793921
43407688	43407711	7	-	27260157	MKN45	viability	CACGGTGTTGCCTATGATCTTGG	HECW1	ENSG00000002746	0.186478861688273	[]	[]	5	hSpCas9	negative selection	2797355
43311867	43311890	7	-	27260157	MKN45	viability	CCATGTTGTGGAACTGGTCGGGG	HECW1	ENSG00000002746	-0.444495443138069	[]	[]	-6	hSpCas9	negative selection	2800465
43320699	43320722	7	-	27260157	MKN45	viability	CATCGATCTTCCAGATGATCTGG	HECW1	ENSG00000002746	0.485249185348092	[]	[]	6	hSpCas9	negative selection	2801768
43311966	43311989	7	-	27260157	RKO	viability	TGCTGACCATGAGCGTGGAGCGG	HECW1	ENSG00000002746	0.631594854610752	[]	[]	3	hSpCas9	negative selection	2811477
43311834	43311857	7	-	27260157	RKO	viability	ATCGGAGCGGCTCCTTGCACCGG	HECW1	ENSG00000002746	-1.10437290991312	[]	[]	-8	hSpCas9	negative selection	2832574
43311985	43312008	7	+	27260157	RKO	viability	AGCAGCTCCTACTATTCCATCGG	HECW1	ENSG00000002746	0.649821752470903	[]	[]	3	hSpCas9	negative selection	2832627
43311828	43311851	7	-	27260157	RKO	viability	GCGGCTCCTTGCACCGGCGTCGG	HECW1	ENSG00000002746	-0.742027585615687	[]	[]	-7	hSpCas9	negative selection	2834918
43311868	43311891	7	-	27260157	RKO	viability	TCCATGTTGTGGAACTGGTCGGG	HECW1	ENSG00000002746	-0.608893748082231	[]	[]	-7	hSpCas9	negative selection	2838304
43311925	43311948	7	-	27260157	RKO	viability	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-1.13368919906306	[]	[]	-8	hSpCas9	negative selection	2840216
43320717	43320740	7	+	27260157	RKO	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.469681463527633	[]	[]	2	hSpCas9	negative selection	2845717
43438017	43438040	7	+	27260157	RKO	viability	GTCCTTGCCCACTGACGTGCTGG	HECW1	ENSG00000002746	0.861796621901829	[]	[]	8	hSpCas9	negative selection	2846968
43311815	43311838	7	+	27260157	RKO	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	1.28667296167344	[]	[]	9	hSpCas9	negative selection	2847224
43311996	43312019	7	+	27260157	RKO	viability	CTATTCCATCGGGCACTCTCAGG	HECW1	ENSG00000002746	0.030888847832742	[]	[]	0	hSpCas9	negative selection	2847651
43311847	43311870	7	-	27260157	RKO	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.523993505841937	[]	[]	-6	hSpCas9	negative selection	2848002
43311821	43311844	7	-	27260157	RKO	viability	CTTGCACCGGCGTCGGCTCTGGG	HECW1	ENSG00000002746	-0.224430676592338	[]	[]	-1	hSpCas9	negative selection	2849136
43311789	43311812	7	-	27260157	RKO	viability	AAGGAGACGCCATGGCGGCCAGG	HECW1	ENSG00000002746	2.11143506645366	[]	[]	9	hSpCas9	negative selection	2851064
43312013	43312036	7	+	27260157	RKO	viability	CTCAGGACCTGGTCATCCACTGG	HECW1	ENSG00000002746	0.956229791545655	[]	[]	8	hSpCas9	negative selection	2852320
43311758	43311781	7	+	27260157	RKO	viability	CACAGAATCTGTACCAGAACAGG	HECW1	ENSG00000002746	1.25285122583813	[]	[]	9	hSpCas9	negative selection	2870051
43407688	43407711	7	-	27260157	RKO	viability	CACGGTGTTGCCTATGATCTTGG	HECW1	ENSG00000002746	0.168242510534045	[]	[]	0	hSpCas9	negative selection	2873485
43311867	43311890	7	-	27260157	RKO	viability	CCATGTTGTGGAACTGGTCGGGG	HECW1	ENSG00000002746	0.312474531370071	[]	[]	1	hSpCas9	negative selection	2876595
43320699	43320722	7	-	27260157	RKO	viability	CATCGATCTTCCAGATGATCTGG	HECW1	ENSG00000002746	0.26126180431164	[]	[]	1	hSpCas9	negative selection	2877898
43311966	43311989	7	-	27260157	SF268	viability	TGCTGACCATGAGCGTGGAGCGG	HECW1	ENSG00000002746	0.536802307201686	[]	[]	8	hSpCas9	negative selection	2887607
43311834	43311857	7	-	27260157	SF268	viability	ATCGGAGCGGCTCCTTGCACCGG	HECW1	ENSG00000002746	-0.242896698942998	[]	[]	-2	hSpCas9	negative selection	2908704
43311985	43312008	7	+	27260157	SF268	viability	AGCAGCTCCTACTATTCCATCGG	HECW1	ENSG00000002746	-0.0691587912626054	[]	[]	0	hSpCas9	negative selection	2908757
43311828	43311851	7	-	27260157	SF268	viability	GCGGCTCCTTGCACCGGCGTCGG	HECW1	ENSG00000002746	0.227886064326724	[]	[]	3	hSpCas9	negative selection	2911048
43311868	43311891	7	-	27260157	SF268	viability	TCCATGTTGTGGAACTGGTCGGG	HECW1	ENSG00000002746	-0.201784913116324	[]	[]	-1	hSpCas9	negative selection	2914434
43311925	43311948	7	-	27260157	SF268	viability	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.280449222812317	[]	[]	-2	hSpCas9	negative selection	2916346
43320717	43320740	7	+	27260157	SF268	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.028082303894875	[]	[]	0	hSpCas9	negative selection	2921847
43438017	43438040	7	+	27260157	SF268	viability	GTCCTTGCCCACTGACGTGCTGG	HECW1	ENSG00000002746	0.445701903573307	[]	[]	7	hSpCas9	negative selection	2923098
43311815	43311838	7	+	27260157	SF268	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.258540529446191	[]	[]	4	hSpCas9	negative selection	2923354
43311996	43312019	7	+	27260157	SF268	viability	CTATTCCATCGGGCACTCTCAGG	HECW1	ENSG00000002746	-0.621414798034393	[]	[]	-5	hSpCas9	negative selection	2923781
43311847	43311870	7	-	27260157	SF268	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.47742070679878	[]	[]	-4	hSpCas9	negative selection	2924132
43311821	43311844	7	-	27260157	SF268	viability	CTTGCACCGGCGTCGGCTCTGGG	HECW1	ENSG00000002746	-0.572975470883687	[]	[]	-4	hSpCas9	negative selection	2925266
43311789	43311812	7	-	27260157	SF268	viability	AAGGAGACGCCATGGCGGCCAGG	HECW1	ENSG00000002746	1.73105333417098	[]	[]	9	hSpCas9	negative selection	2927194
43312013	43312036	7	+	27260157	SF268	viability	CTCAGGACCTGGTCATCCACTGG	HECW1	ENSG00000002746	0.443423603336826	[]	[]	7	hSpCas9	negative selection	2928450
43311758	43311781	7	+	27260157	SF268	viability	CACAGAATCTGTACCAGAACAGG	HECW1	ENSG00000002746	0.480577370979707	[]	[]	7	hSpCas9	negative selection	2946181
43407688	43407711	7	-	27260157	SF268	viability	CACGGTGTTGCCTATGATCTTGG	HECW1	ENSG00000002746	0.436395356834183	[]	[]	7	hSpCas9	negative selection	2949615
43311867	43311890	7	-	27260157	SF268	viability	CCATGTTGTGGAACTGGTCGGGG	HECW1	ENSG00000002746	0.116350137577171	[]	[]	0	hSpCas9	negative selection	2952725
43320699	43320722	7	-	27260157	SF268	viability	CATCGATCTTCCAGATGATCTGG	HECW1	ENSG00000002746	-0.0547594707531562	[]	[]	0	hSpCas9	negative selection	2954028
43444822	43444845	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGGGGACCCCGAGACCCCGCGG	HECW1	ENSG00000002746	0.3612297466541202	[1,2]	[3,1]	7	hSpCas9	positive selection	2992988
43444953	43444976	7	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGAGCCCATCCTTCTCCGAGG	HECW1	ENSG00000002746	-0.37205154723343176	[3,3]	[3,0]	-5	hSpCas9	positive selection	2992989
43444424	43444447	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAGCAGCAGTCATCACGGAGG	HECW1	ENSG00000002746	0.3516755195611075	[3,3]	[2,4]	7	hSpCas9	positive selection	2992990
43407557	43407580	7	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTATAGATTTCCAAGCCATGGGG	HECW1	ENSG00000002746	0.30041057314385117	[3,3]	[3,3]	6	hSpCas9	positive selection	2992991
43444822	43444845	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGGGGACCCCGAGACCCCGCGG	HECW1	ENSG00000002746	0.14262895827547933	[1,1]	[2,0]	2	hSpCas9	positive selection	3060846
43444953	43444976	7	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGAGCCCATCCTTCTCCGAGG	HECW1	ENSG00000002746	-0.23789841897898129	[3,3]	[2,0]	-3	hSpCas9	positive selection	3060847
43444424	43444447	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAGCAGCAGTCATCACGGAGG	HECW1	ENSG00000002746	-0.47943869242470993	[3,3]	[3,0]	-6	hSpCas9	positive selection	3060848
43407557	43407580	7	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTATAGATTTCCAAGCCATGGGG	HECW1	ENSG00000002746	-0.4699487360416498	[3,3]	[3,0]	-6	hSpCas9	positive selection	3060849
43360938	43360961		+	24336571	A375	resistance to PLX after 7 days	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.6548120069401616	[12,13]	[20,21]	9	hSpCas9	positive selection	3118731
43360949	43360972		-	24336571	A375	resistance to PLX after 7 days	CGAGTTTTTGACCGTGACACTGG	HECW1	ENSG00000002746	-0.0810419912728752	[13,18]	[15,13]	-2	hSpCas9	positive selection	3118732
43320717	43320740		+	24336571	A375	resistance to PLX after 7 days	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.10289535988532486	[14,13]	[12,12]	-3	hSpCas9	positive selection	3118733
43320639	43320662		+	24336571	A375	resistance to PLX after 7 days	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.05267222641837899	[5,3]	[4,4]	2	hSpCas9	positive selection	3118734
43360938	43360961		+	24336571	A375	resistance to PLX after 14 days	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	5.195071106735311	[7,11]	[143,213]	9	hSpCas9	positive selection	3176524
43360949	43360972		-	24336571	A375	resistance to PLX after 14 days	CGAGTTTTTGACCGTGACACTGG	HECW1	ENSG00000002746	-0.3951997083585004	[11,19]	[5,4]	-5	hSpCas9	positive selection	3176525
43320717	43320740		+	24336571	A375	resistance to PLX after 14 days	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.0532835747271205	[11,10]	[4,4]	0	hSpCas9	positive selection	3176526
43320639	43320662		+	24336571	A375	resistance to PLX after 14 days	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.7487328412071271	[4,3]	[3,2]	6	hSpCas9	positive selection	3176527
43360938	43360961		+	24336571	A375	viability after 7 days	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.03140763920508947	[13]	[12,13]	0	hSpCas9	negative selection	3234317
43360949	43360972		-	24336571	A375	viability after 7 days	CGAGTTTTTGACCGTGACACTGG	HECW1	ENSG00000002746	-0.02696041487232609	[17]	[13,18]	0	hSpCas9	negative selection	3234318
43320717	43320740		+	24336571	A375	viability after 7 days	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.6075460354608749	[9]	[14,13]	8	hSpCas9	negative selection	3234319
43320639	43320662		+	24336571	A375	viability after 7 days	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	-0.4148996134528782	[6]	[5,3]	-5	hSpCas9	negative selection	3234320
43360938	43360961		+	24336571	A375	viability after 14 days	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.3739535899160861	[13]	[7,11]	-4	hSpCas9	negative selection	3292110
43360949	43360972		-	24336571	A375	viability after 14 days	CGAGTTTTTGACCGTGACACTGG	HECW1	ENSG00000002746	-0.02397775953724085	[17]	[11,19]	0	hSpCas9	negative selection	3292111
43320717	43320740		+	24336571	A375	viability after 14 days	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.31084943486731664	[9]	[11,10]	4	hSpCas9	negative selection	3292112
43320639	43320662		+	24336571	A375	viability after 14 days	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	-0.4309297915463286	[6]	[4,3]	-5	hSpCas9	negative selection	3292113
43320717	43320740	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	3.4513189728499776	[11,15]	[0,0]	9	hSpCas9	positive selection	3353197
43320639	43320662	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.7012334557011368	[108,78]	[0,0]	3	hSpCas9	positive selection	3353198
43396846	43396869	7	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	-1.186104928497747	[365,329]	[0,0]	-7	hSpCas9	positive selection	3353199
43396835	43396858	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.13499121133292535	[167,167]	[0,0]	-1	hSpCas9	positive selection	3372393
43360938	43360961	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-1.0825237914387897	[323,323]	[0,0]	-7	hSpCas9	positive selection	3372394
43360897	43360920	7	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	1.7337642553888224	[45,45]	[0,0]	7	hSpCas9	positive selection	3372395
43444821	43444844	7	+	26780180	HT29	viability (Avana library 4 designs)	GCGGGGACCCCGAGACCCCGCGG	HECW1	ENSG00000002746	0.386839844758752	[]	[]	1	hSpCas9	negative selection	3430249
43444953	43444976	7	-	26780180	HT29	viability (Avana library 4 designs)	GCTGAGCCCATCCTTCTCCGAGG	HECW1	ENSG00000002746	0.53303596873701	[]	[]	2	hSpCas9	negative selection	3430250
43444423	43444446	7	+	26780180	HT29	viability (Avana library 4 designs)	GGAAGCAGCAGTCATCACGGAGG	HECW1	ENSG00000002746	1.38408970295258	[]	[]	5	hSpCas9	negative selection	3430251
43407556	43407579	7	+	26780180	HT29	viability (Avana library 4 designs)	TTATAGATTTCCAAGCCATGGGG	HECW1	ENSG00000002746	1.33120301713123	[]	[]	5	hSpCas9	negative selection	3430252
43444953	43444976	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAGCCCATCCTTCTCCGAGG	HECW1	ENSG00000002746	4.65746558073405	[]	[]	7	hSpCas9	negative selection	3515316
43444423	43444446	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAGCAGCAGTCATCACGGAGG	HECW1	ENSG00000002746	4.19283450975564	[]	[]	7	hSpCas9	negative selection	3515317
43407556	43407579	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTATAGATTTCCAAGCCATGGGG	HECW1	ENSG00000002746	-4.21293362452722	[]	[]	-5	hSpCas9	negative selection	3515318
43444821	43444844	7	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGGGACCCCGAGACCCCGCGG	HECW1	ENSG00000002746	1.18170820287385	[]	[]	1	hSpCas9	negative selection	3515319
43444836	43444859	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	5.8982717639694	[]	[]	9	hSpCas9	negative selection	3515320
43444713	43444736	7	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCCCTCTCCCTGCTCCAGGG	HECW1	ENSG00000002746	2.83753728921087	[]	[]	4	hSpCas9	negative selection	3515321
43444953	43444976	7	-	26780180	A375	viability (Avana lentiGuide)	GCTGAGCCCATCCTTCTCCGAGG	HECW1	ENSG00000002746	-0.445675759047235	[]	[]	0	hSpCas9	negative selection	3623975
43444423	43444446	7	+	26780180	A375	viability (Avana lentiGuide)	GGAAGCAGCAGTCATCACGGAGG	HECW1	ENSG00000002746	-3.81856353941749	[]	[]	-6	hSpCas9	negative selection	3623976
43407556	43407579	7	+	26780180	A375	viability (Avana lentiGuide)	TTATAGATTTCCAAGCCATGGGG	HECW1	ENSG00000002746	-0.632601832896499	[]	[]	-1	hSpCas9	negative selection	3623977
43444821	43444844	7	+	26780180	A375	viability (Avana lentiGuide)	GCGGGGACCCCGAGACCCCGCGG	HECW1	ENSG00000002746	-4.86868196229592	[]	[]	-8	hSpCas9	negative selection	3623978
43444836	43444859	7	-	26780180	A375	viability (Avana lentiGuide)	GCGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	-1.27956922757958	[]	[]	-2	hSpCas9	negative selection	3623979
43444713	43444736	7	-	26780180	A375	viability (Avana lentiGuide)	CCTGCCCTCTCCCTGCTCCAGGG	HECW1	ENSG00000002746	3.27899248545608	[]	[]	3	hSpCas9	negative selection	3623980
43444953	43444976	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAGCCCATCCTTCTCCGAGG	HECW1	ENSG00000002746	0.1671888008027491	[4]	[4,5]	4	hSpCas9	positive selection	3732634
43444423	43444446	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAGCAGCAGTCATCACGGAGG	HECW1	ENSG00000002746	0.25315465280124694	[4]	[5,4]	7	hSpCas9	positive selection	3732635
43407556	43407579	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTATAGATTTCCAAGCCATGGGG	HECW1	ENSG00000002746	-0.4314946313600713	[6]	[4,3]	-6	hSpCas9	positive selection	3732636
43444821	43444844	7	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGGGACCCCGAGACCCCGCGG	HECW1	ENSG00000002746	0.0029720128076897168	[3]	[3,3]	0	hSpCas9	positive selection	3732637
43444836	43444859	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.42553269663633986	[4]	[6,5]	9	hSpCas9	positive selection	3732638
43444713	43444736	7	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCCCTCTCCCTGCTCCAGGG	HECW1	ENSG00000002746	0.08164246106492588	[4]	[4,4]	2	hSpCas9	positive selection	3732639
43444953	43444976	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAGCCCATCCTTCTCCGAGG	HECW1	ENSG00000002746	-0.020045183482913623	[5]	[4,4]	0	hSpCas9	positive selection	3841241
43444423	43444446	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAGCAGCAGTCATCACGGAGG	HECW1	ENSG00000002746	-0.2125997471966966	[5]	[4,2]	-3	hSpCas9	positive selection	3841242
43407556	43407579	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTATAGATTTCCAAGCCATGGGG	HECW1	ENSG00000002746	-0.002476926121714393	[5]	[2,5]	0	hSpCas9	positive selection	3841243
43444821	43444844	7	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGGGACCCCGAGACCCCGCGG	HECW1	ENSG00000002746	0.10262479719996098	[3]	[2,3]	2	hSpCas9	positive selection	3841244
43444836	43444859	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.42399505615022803	[4]	[5,5]	9	hSpCas9	positive selection	3841245
43444713	43444736	7	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCCCTCTCCCTGCTCCAGGG	HECW1	ENSG00000002746	-0.21396913355576114	[6]	[5,2]	-3	hSpCas9	positive selection	3841246
43360938	43360961	7	+	26780180	A375	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.883132108774362	[]	[]	3	hSpCas9	negative selection	3947313
43360897	43360920	7	+	26780180	A375	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	1.09869380260608	[]	[]	5	hSpCas9	negative selection	3947314
43320717	43320740	7	+	26780180	A375	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.436582467541224	[]	[]	1	hSpCas9	negative selection	3947315
43396835	43396858	7	+	26780180	A375	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.258812732146436	[]	[]	0	hSpCas9	negative selection	3947316
43396846	43396869	7	-	26780180	A375	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.0997055858779121	[]	[]	0	hSpCas9	negative selection	3947317
43320639	43320662	7	+	26780180	A375	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.418109726617687	[]	[]	1	hSpCas9	negative selection	3947318
43360938	43360961	7	+	26780180	HT29	viability (GeCKOv2 library)	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.745664736788266	[]	[]	3	hSpCas9	negative selection	4055279
43360897	43360920	7	+	26780180	HT29	viability (GeCKOv2 library)	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	1.08012132578634	[]	[]	5	hSpCas9	negative selection	4055280
43320717	43320740	7	+	26780180	HT29	viability (GeCKOv2 library)	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.654097103233184	[]	[]	2	hSpCas9	negative selection	4055281
43396835	43396858	7	+	26780180	HT29	viability (GeCKOv2 library)	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	1.60683568079413	[]	[]	8	hSpCas9	negative selection	4055282
43396846	43396869	7	-	26780180	HT29	viability (GeCKOv2 library)	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	-0.67299496962167	[]	[]	-9	hSpCas9	negative selection	4055283
43320639	43320662	7	+	26780180	HT29	viability (GeCKOv2 library)	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.262300643516852	[]	[]	0	hSpCas9	negative selection	4055284
43360938	43360961	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.8434869445370811	[3]	[2,7]	9	hSpCas9	positive selection	4142190
43360949	43360972	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGTTTTTGACCGTGACACTGG	HECW1	ENSG00000002746	-0.02463882500655745	[3]	[2,2]	0	hSpCas9	positive selection	4142191
43320717	43320740	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.11599572211989578	[3]	[2,2]	3	hSpCas9	positive selection	4142192
43320639	43320662	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	-0.1792788169120344	[2]	[0,1]	-4	hSpCas9	positive selection	4142193
43360938	43360961	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	1.2709097682734753	[3]	[5,2,2,4]	9	hSpCas9	positive selection	4206212
43360949	43360972	7	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGTTTTTGACCGTGACACTGG	HECW1	ENSG00000002746	0.16714299413421901	[2]	[0,2,1,0]	1	hSpCas9	positive selection	4206213
43320717	43320740	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	1.146150343646522	[3]	[2,2,0,4]	8	hSpCas9	positive selection	4206214
43320639	43320662	7	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.7001167631343432	[1]	[0,2,0,0]	4	hSpCas9	positive selection	4206215
43320717	43320740	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.1203422565822947	[0]	[0,0]	-2	hSpCas9	positive selection	4274781
43320639	43320662	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.35689604442918804	[2]	[2,2]	7	hSpCas9	positive selection	4274782
43396846	43396869	7	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.21778230060016662	[4]	[4,3]	4	hSpCas9	positive selection	4274783
43396835	43396858	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.10612157066294252	[2]	[3,1]	2	hSpCas9	positive selection	4339042
43360938	43360961	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.041891966080178145	[3]	[3,1]	-1	hSpCas9	positive selection	4339043
43360897	43360920	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.07659896977427999	[2]	[2,0]	1	hSpCas9	positive selection	4339044
43479409	43479432	7	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.0962305667158467	[3]	[1,0]	-9	hSpCas9	positive selection	4363570
43311847	43311869	7	-	27760321	OCIAML3	viability	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.148372523826553	[403,354]	[372,269]	1	hSpCas9	negative selection	4406554
43444836	43444858	7	-	27760321	OCIAML3	viability	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	-0.2539884374002441	[289,285]	[135,258]	-3	hSpCas9	negative selection	4406555
43445396	43445418	7	+	27760321	OCIAML3	viability	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.9208439546754545	[390,300]	[117,172]	-7	hSpCas9	negative selection	4406556
43445452	43445474	7	+	27760321	OCIAML3	viability	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	0.6776372949356982	[225,181]	[248,259]	7	hSpCas9	negative selection	4406557
43445493	43445515	7	-	27760321	OCIAML3	viability	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.661289509659476	[522,451]	[573,636]	7	hSpCas9	negative selection	4406558
43311847	43311869	7	-	27760321	OCIAML2	viability	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.06962367379191409	[403,354]	[264,395]	0	hSpCas9	negative selection	4490017
43444836	43444858	7	-	27760321	OCIAML2	viability	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.8178224386702704	[289,285]	[315,537]	9	hSpCas9	negative selection	4490018
43445396	43445418	7	+	27760321	OCIAML2	viability	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	0.04656620113126736	[390,300]	[273,303]	0	hSpCas9	negative selection	4490019
43445452	43445474	7	+	27760321	OCIAML2	viability	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	1.3978409921801402	[225,181]	[409,461]	9	hSpCas9	negative selection	4490020
43445493	43445515	7	-	27760321	OCIAML2	viability	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.37445354154470417	[522,451]	[508,510]	5	hSpCas9	negative selection	4490021
43311847	43311869	7	-	27760321	MV411	viability	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.6920545872866993	[403,354]	[31,338]	-5	hSpCas9	negative selection	4573480
43444836	43444858	7	-	27760321	MV411	viability	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.9714899243645838	[289,285]	[465,234]	7	hSpCas9	negative selection	4573481
43445396	43445418	7	+	27760321	MV411	viability	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	1.2653882244286017	[390,300]	[808,147]	8	hSpCas9	negative selection	4573482
43445452	43445474	7	+	27760321	MV411	viability	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	1.6298707757400905	[225,181]	[544,217]	9	hSpCas9	negative selection	4573483
43445493	43445515	7	-	27760321	MV411	viability	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	-0.3519543139898813	[522,451]	[228,284]	-2	hSpCas9	negative selection	4573484
43311847	43311869	7	-	27760321	HL60	viability	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.20132586022334728	[403,354]	[312,400]	2	hSpCas9	negative selection	4656943
43444836	43444858	7	-	27760321	HL60	viability	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.32767134695987626	[289,285]	[247,346]	4	hSpCas9	negative selection	4656944
43445396	43445418	7	+	27760321	HL60	viability	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.22996144052961182	[390,300]	[295,178]	-3	hSpCas9	negative selection	4656945
43445452	43445474	7	+	27760321	HL60	viability	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	0.7448812081057412	[225,181]	[234,322]	8	hSpCas9	negative selection	4656946
43445493	43445515	7	-	27760321	HL60	viability	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.1641028028823614	[522,451]	[444,444]	2	hSpCas9	negative selection	4656947
43311847	43311869	7	-	27760321	HT1080	viability	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.43161357670101264	[354,276]	[238,93]	2	hSpCas9	negative selection	4740406
43444836	43444858	7	-	27760321	HT1080	viability	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.9104100403510462	[285,222]	[159,223]	5	hSpCas9	negative selection	4740407
43445396	43445418	7	+	27760321	HT1080	viability	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-1.8644620913563212	[300,234]	[14,44]	-6	hSpCas9	negative selection	4740408
43445452	43445474	7	+	27760321	HT1080	viability	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	0.2954615513585933	[181,141]	[93,62]	1	hSpCas9	negative selection	4740409
43445493	43445515	7	-	27760321	HT1080	viability	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	1.9637115204689615	[451,352]	[666,579]	9	hSpCas9	negative selection	4740410
43311847	43311869	7	-	27760321	HT29	viability after 7 days	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.27547563642998	[354,276]	[490,381,597]	4	hSpCas9	negative selection	4823869
43444836	43444858	7	-	27760321	HT29	viability after 7 days	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.13845364356955037	[285,222]	[282,427,357]	2	hSpCas9	negative selection	4823870
43445396	43445418	7	+	27760321	HT29	viability after 7 days	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.4154688793830924	[300,234]	[327,241,215]	-6	hSpCas9	negative selection	4823871
43445452	43445474	7	+	27760321	HT29	viability after 7 days	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	0.6936999106888451	[181,141]	[262,252,478]	9	hSpCas9	negative selection	4823872
43445493	43445515	7	-	27760321	HT29	viability after 7 days	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.42492667368911863	[451,352]	[867,830,417]	6	hSpCas9	negative selection	4823873
43311847	43311869	7	-	27760321	HT29	viability after 25 days	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.09916771493503079	[354,276]	[319,302,394]	-1	hSpCas9	negative selection	4907332
43444836	43444858	7	-	27760321	HT29	viability after 25 days	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.43758861069690924	[285,222]	[465,389,311]	5	hSpCas9	negative selection	4907333
43445396	43445418	7	+	27760321	HT29	viability after 25 days	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.025735978945327087	[300,234]	[329,297,268]	0	hSpCas9	negative selection	4907334
43445452	43445474	7	+	27760321	HT29	viability after 25 days	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	1.243635175766297	[181,141]	[366,435,524]	9	hSpCas9	negative selection	4907335
43445493	43445515	7	-	27760321	HT29	viability after 25 days	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.5524226466627143	[451,352]	[638,737,644]	6	hSpCas9	negative selection	4907336
43311847	43311869	7	-	27760321	HT29	viability after 22 days	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.2740770376238408	[354,276]	[646,297,373]	3	hSpCas9	negative selection	4990795
43444836	43444858	7	-	27760321	HT29	viability after 22 days	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	-0.17684166808726115	[285,222]	[333,264,178]	-2	hSpCas9	negative selection	4990796
43445396	43445418	7	+	27760321	HT29	viability after 22 days	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.25264282384636694	[300,234]	[341,169,265]	-3	hSpCas9	negative selection	4990797
43445452	43445474	7	+	27760321	HT29	viability after 22 days	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	0.7370018675126194	[181,141]	[276,383,275]	8	hSpCas9	negative selection	4990798
43445493	43445515	7	-	27760321	HT29	viability after 22 days	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.45026169597570986	[451,352]	[527,767,613]	5	hSpCas9	negative selection	4990799
43311847	43311869	7	-	27760321	HT29	viability after 19 days	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.44992734819298774	[354,276]	[370,554,539]	4	hSpCas9	negative selection	5074258
43444836	43444858	7	-	27760321	HT29	viability after 19 days	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.25052877749888147	[285,222]	[542,354,167]	2	hSpCas9	negative selection	5074259
43445396	43445418	7	+	27760321	HT29	viability after 19 days	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.5388867371342637	[300,234]	[333,243,72]	-5	hSpCas9	negative selection	5074260
43445452	43445474	7	+	27760321	HT29	viability after 19 days	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	1.4140313948500858	[181,141]	[363,254,834]	9	hSpCas9	negative selection	5074261
43445493	43445515	7	-	27760321	HT29	viability after 19 days	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.8742810713413953	[451,352]	[818,532,1163]	8	hSpCas9	negative selection	5074262
43311847	43311869	7	-	27760321	HT29	viability after 16 days	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.5288167557631629	[354,276]	[166,310,247]	-5	hSpCas9	negative selection	5157721
43444836	43444858	7	-	27760321	HT29	viability after 16 days	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.4208385237059237	[285,222]	[619,264,283]	5	hSpCas9	negative selection	5157722
43445396	43445418	7	+	27760321	HT29	viability after 16 days	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	0.07142181604933223	[300,234]	[225,227,484]	0	hSpCas9	negative selection	5157723
43445452	43445474	7	+	27760321	HT29	viability after 16 days	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	1.11307534061268	[181,141]	[537,117,540]	9	hSpCas9	negative selection	5157724
43445493	43445515	7	-	27760321	HT29	viability after 16 days	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.3409467885251054	[451,352]	[814,615,301]	4	hSpCas9	negative selection	5157725
43311847	43311869	7	-	27760321	HT29	viability after 13 days	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.3264748004341752	[354,276]	[167,343,360]	-4	hSpCas9	negative selection	5241184
43444836	43444858	7	-	27760321	HT29	viability after 13 days	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	-0.16408212975106112	[285,222]	[270,248,269]	-2	hSpCas9	negative selection	5241185
43445396	43445418	7	+	27760321	HT29	viability after 13 days	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.1290012738496079	[300,234]	[437,154,260]	-1	hSpCas9	negative selection	5241186
43445452	43445474	7	+	27760321	HT29	viability after 13 days	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	1.392107598887113	[181,141]	[472,381,616]	9	hSpCas9	negative selection	5241187
43445493	43445515	7	-	27760321	HT29	viability after 13 days	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.38671110093512007	[451,352]	[645,483,695]	5	hSpCas9	negative selection	5241188
43311847	43311869	7	-	27760321	HT29	viability after 10 days	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.1718910416682368	[354,276]	[442,458,431]	2	hSpCas9	negative selection	5324647
43444836	43444858	7	-	27760321	HT29	viability after 10 days	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	-0.33040986387437393	[285,222]	[273,261,222]	-4	hSpCas9	negative selection	5324648
43445396	43445418	7	+	27760321	HT29	viability after 10 days	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	-0.8637183415276909	[300,234]	[166,218,166]	-7	hSpCas9	negative selection	5324649
43445452	43445474	7	+	27760321	HT29	viability after 10 days	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	0.7544428164605534	[181,141]	[288,372,361]	8	hSpCas9	negative selection	5324650
43445493	43445515	7	-	27760321	HT29	viability after 10 days	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	0.4832437197850643	[451,352]	[575,789,742]	6	hSpCas9	negative selection	5324651
43311847	43311869	7	-	27760321	MOLM13	viability	GGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.8309646981024074	[403,354]	[344,409]	6	hSpCas9	negative selection	5408110
43444836	43444858	7	-	27760321	MOLM13	viability	CGGATGTAGTGTGTCCGCGGGG	HECW1	ENSG00000002746	0.7856047311080944	[289,285]	[349,221]	5	hSpCas9	negative selection	5408111
43445396	43445418	7	+	27760321	MOLM13	viability	GAGAACAGCGCGTTCGAGTCGG	HECW1	ENSG00000002746	0.08769282523245381	[390,300]	[233,181]	0	hSpCas9	negative selection	5408112
43445452	43445474	7	+	27760321	MOLM13	viability	GGAGTCCACGAACGGCGCTGGG	HECW1	ENSG00000002746	1.2589963832696156	[225,181]	[395,169]	8	hSpCas9	negative selection	5408113
43445493	43445515	7	-	27760321	MOLM13	viability	TCCACGTGCCCGCTAGGGGCGG	HECW1	ENSG00000002746	1.0677914356958718	[522,451]	[500,637]	7	hSpCas9	negative selection	5408114
43112669	43112692	7	-	27661255	K562	viability	GTCAGAGTCGCACGGTGTTCCGG	HECW1	ENSG00000002746	-0.13318268445562437	[1145,1112]	[868,783]	-4	dCas9-KRAB	negative selection	5484393
43112875	43112898	7	-	27661255	K562	viability	GCGCGCAGATTAGAGCTGGGGGG	HECW1	ENSG00000002746	0.201224967348544	[416,367]	[377,346]	7	dCas9-KRAB	negative selection	5484394
43113036	43113059	7	-	27661255	K562	viability	GTGGATCTCGGCCCCGAGAAGGG	HECW1	ENSG00000002746	0.18244273818821805	[940,1107]	[1081,792]	6	dCas9-KRAB	negative selection	5484395
43114023	43114046	7	-	27661255	K562	viability	GAAAATCCCCACATGCTCTCTGG	HECW1	ENSG00000002746	-0.0944849582503211	[173,211]	[158,130]	-4	dCas9-KRAB	negative selection	5484396
43114436	43114459	7	-	27661255	K562	viability	GGACTCTAATCCCTTCTTAGTGG	HECW1	ENSG00000002746	0.28308928762668195	[132,199]	[144,173]	8	dCas9-KRAB	negative selection	5484397
43320717	43320740	7	+	27260156	BXPC3	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.23368971634907432	[41]	[36,32,42,101]	5	hSpCas9	negative selection	5547241
43320639	43320662	7	+	27260156	BXPC3	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.6039210933183861	[312]	[420,572,381,627]	9	hSpCas9	negative selection	5547242
43396846	43396869	7	-	27260156	BXPC3	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.42332346810664956	[1227]	[1567,1750,1763,1819]	8	hSpCas9	negative selection	5547243
43396835	43396858	7	+	27260156	BXPC3	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.06102723950711708	[354]	[290,269,461,563]	1	hSpCas9	negative selection	5611502
43360938	43360961	7	+	27260156	BXPC3	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.09924654783827891	[732]	[639,597,779,874]	-2	hSpCas9	negative selection	5611503
43360897	43360920	7	+	27260156	BXPC3	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.003712553291180143	[205]	[139,352,144,218]	0	hSpCas9	negative selection	5611504
43479409	43479432	7	+	27260156	BXPC3	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.2572167297412158	[880]	[323,333,405,498]	-9	hSpCas9	negative selection	5636030
43320717	43320740	7	+	27260156	A673	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.6245996822406612	[41]	[101,37,118,53]	9	hSpCas9	negative selection	5668492
43320639	43320662	7	+	27260156	A673	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.5771709551804995	[312]	[731,556,513,452]	9	hSpCas9	negative selection	5668493
43396846	43396869	7	-	27260156	A673	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.4681523962334979	[1227]	[2330,1614,2065,2195]	9	hSpCas9	negative selection	5668494
43396835	43396858	7	+	27260156	A673	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.27521097832537006	[354]	[358,331,371,345]	-6	hSpCas9	negative selection	5732753
43360938	43360961	7	+	27260156	A673	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.08615895234835969	[732]	[815,948,969,988]	2	hSpCas9	negative selection	5732754
43360897	43360920	7	+	27260156	A673	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.03159074319576849	[205]	[296,172,196,312]	-1	hSpCas9	negative selection	5732755
43479409	43479432	7	+	27260156	A673	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.49460054272686405	[880]	[755,765,672,810]	-8	hSpCas9	negative selection	5757281
43320717	43320740	7	+	27260156	A375	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.19352441193235492	[41]	[22,83,47,70]	2	hSpCas9	negative selection	5789743
43320639	43320662	7	+	27260156	A375	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.6023451293922255	[312]	[565,577,538,539]	8	hSpCas9	negative selection	5789744
43396846	43396869	7	-	27260156	A375	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5071583604307663	[1227]	[2293,2033,2055,1792]	7	hSpCas9	negative selection	5789745
43396835	43396858	7	+	27260156	A375	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.20797184811070818	[354]	[262,216,472,449]	-3	hSpCas9	negative selection	5854004
43360938	43360961	7	+	27260156	A375	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.0105683161995479	[732]	[742,818,866,949]	0	hSpCas9	negative selection	5854005
43360897	43360920	7	+	27260156	A375	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.21436861140432262	[205]	[190,276,187,184]	-3	hSpCas9	negative selection	5854006
43479409	43479432	7	+	27260156	A375	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-2.5519102920084804	[880]	[170,207,153,172]	-9	hSpCas9	negative selection	5878532
43320717	43320740	7	+	27260156	COLO741	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.09855718310483175	[41]	[79,62,32]	2	hSpCas9	negative selection	5910994
43320639	43320662	7	+	27260156	COLO741	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.45995822694519606	[312]	[404,541,679]	8	hSpCas9	negative selection	5910995
43396846	43396869	7	-	27260156	COLO741	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.2849591446850881	[1227]	[1985,1938,1818]	6	hSpCas9	negative selection	5910996
43396835	43396858	7	+	27260156	COLO741	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.16777271415506534	[354]	[458,606,460]	3	hSpCas9	negative selection	5975255
43360938	43360961	7	+	27260156	COLO741	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.38701083448386586	[732]	[686,816,645]	-7	hSpCas9	negative selection	5975256
43360897	43360920	7	+	27260156	COLO741	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.060639481788044236	[205]	[247,280,228]	-1	hSpCas9	negative selection	5975257
43479409	43479432	7	+	27260156	COLO741	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.8688855205046476	[880]	[791,477,593]	-9	hSpCas9	negative selection	5999783
43320717	43320740	7	+	27260156	CAL120	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.4161531054130654	[41]	[54,32,31]	-6	hSpCas9	negative selection	6032245
43320639	43320662	7	+	27260156	CAL120	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.5672960245360155	[312]	[800,507,457]	8	hSpCas9	negative selection	6032246
43396846	43396869	7	-	27260156	CAL120	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.23989041039173054	[1227]	[2350,1668,1480]	3	hSpCas9	negative selection	6032247
43396835	43396858	7	+	27260156	CAL120	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.4616337206126471	[354]	[338,194,428]	-6	hSpCas9	negative selection	6096506
43360938	43360961	7	+	27260156	CAL120	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.011145556396931156	[732]	[1312,891,616]	0	hSpCas9	negative selection	6096507
43360897	43360920	7	+	27260156	CAL120	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.12130411640892924	[205]	[279,276,157]	-2	hSpCas9	negative selection	6096508
43479409	43479432	7	+	27260156	CAL120	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.0814780611633412	[880]	[497,538,513]	-8	hSpCas9	negative selection	6121034
43320717	43320740	7	+	27260156	CADOES1	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.027900544583710385	[41]	[67,35,40,6]	0	hSpCas9	negative selection	6153496
43320639	43320662	7	+	27260156	CADOES1	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.38836155617077484	[312]	[309,456,362,394]	6	hSpCas9	negative selection	6153497
43396846	43396869	7	-	27260156	CADOES1	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.3534618694878442	[1227]	[1602,1218,1703,1303]	6	hSpCas9	negative selection	6153498
43396835	43396858	7	+	27260156	CADOES1	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.0570489265503637	[354]	[306,343,405,315]	1	hSpCas9	negative selection	6217757
43360938	43360961	7	+	27260156	CADOES1	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.22996022886201972	[732]	[573,516,601,633]	-4	hSpCas9	negative selection	6217758
43360897	43360920	7	+	27260156	CADOES1	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.3221942614052915	[205]	[171,110,197,130]	-5	hSpCas9	negative selection	6217759
43479409	43479432	7	+	27260156	CADOES1	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.9916561292129058	[880]	[362,268,426,595]	-9	hSpCas9	negative selection	6242285
43320717	43320740	7	+	27260156	EWS502	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.3630358511655096	[41]	[69,6,89,62]	6	hSpCas9	negative selection	6274747
43320639	43320662	7	+	27260156	EWS502	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.6210601693936525	[312]	[521,439,659,411]	9	hSpCas9	negative selection	6274748
43396846	43396869	7	-	27260156	EWS502	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.4490680459954821	[1227]	[1616,2073,1821,1575]	7	hSpCas9	negative selection	6274749
43396835	43396858	7	+	27260156	EWS502	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.23728164497225485	[354]	[452,307,529,488]	4	hSpCas9	negative selection	6339008
43360938	43360961	7	+	27260156	EWS502	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.02676837107430252	[732]	[695,759,691,1041]	0	hSpCas9	negative selection	6339009
43360897	43360920	7	+	27260156	EWS502	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.08846563990844003	[205]	[237,197,205,171]	-2	hSpCas9	negative selection	6339010
43479409	43479432	7	+	27260156	EWS502	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.3492053361071386	[880]	[266,272,453,495]	-9	hSpCas9	negative selection	6363536
43320717	43320740	7	+	27260156	EW8	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.971305489558878	[41]	[96,94,38,43]	9	hSpCas9	negative selection	6395998
43320639	43320662	7	+	27260156	EW8	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.4029379004995476	[312]	[299,359,417,244]	7	hSpCas9	negative selection	6395999
43396846	43396869	7	-	27260156	EW8	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5896263895409661	[1227]	[1791,1656,1296,1307]	9	hSpCas9	negative selection	6396000
43396835	43396858	7	+	27260156	EW8	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.009456189194423703	[354]	[372,199,266,329]	0	hSpCas9	negative selection	6460259
43360938	43360961	7	+	27260156	EW8	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.16659129523783012	[732]	[911,599,493,714]	3	hSpCas9	negative selection	6460260
43360897	43360920	7	+	27260156	EW8	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.021714995535221382	[205]	[277,72,108,238]	0	hSpCas9	negative selection	6460261
43479409	43479432	7	+	27260156	EW8	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.3030389588651294	[880]	[312,379,318,142]	-9	hSpCas9	negative selection	6484787
43320717	43320740	7	+	27260156	CORL105	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.0628257203501148	[41]	[30,31,28,92]	-1	hSpCas9	negative selection	6517249
43320639	43320662	7	+	27260156	CORL105	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.3844491888520519	[312]	[443,397,671,429]	7	hSpCas9	negative selection	6517250
43396846	43396869	7	-	27260156	CORL105	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.29181324364257555	[1227]	[1446,1832,2042,1747]	5	hSpCas9	negative selection	6517251
43396835	43396858	7	+	27260156	CORL105	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.01337007500018006	[354]	[573,274,478,337]	0	hSpCas9	negative selection	6581510
43360938	43360961	7	+	27260156	CORL105	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.013545140322042903	[732]	[866,700,1049,816]	0	hSpCas9	negative selection	6581511
43360897	43360920	7	+	27260156	CORL105	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.2059744440638963	[205]	[290,244,286,291]	4	hSpCas9	negative selection	6581512
43479409	43479432	7	+	27260156	CORL105	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.2258176163426207	[880]	[438,559,360,388]	-9	hSpCas9	negative selection	6606038
43320717	43320740	7	+	27260156	HS294T	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.5183879415875556	[41]	[18,32,17,22]	7	hSpCas9	negative selection	6638500
43320639	43320662	7	+	27260156	HS294T	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	-0.15624018770925197	[312]	[88,137,88,120]	-2	hSpCas9	negative selection	6638501
43396846	43396869	7	-	27260156	HS294T	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.4959163730217082	[1227]	[643,542,805,693]	6	hSpCas9	negative selection	6638502
43396835	43396858	7	+	27260156	HS294T	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.24334295503394793	[354]	[122,74,110,162]	-3	hSpCas9	negative selection	6702761
43360938	43360961	7	+	27260156	HS294T	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.19011205227819084	[732]	[257,276,252,549]	2	hSpCas9	negative selection	6702762
43360897	43360920	7	+	27260156	HS294T	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.015161277994474753	[205]	[79,31,152,53]	0	hSpCas9	negative selection	6702763
43479409	43479432	7	+	27260156	HS294T	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.0148168668044366	[880]	[124,102,224,238]	-9	hSpCas9	negative selection	6727289
43320717	43320740	7	+	27260156	HCC44	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.5486661969879698	[41]	[58,51,159,24]	8	hSpCas9	negative selection	6759751
43320639	43320662	7	+	27260156	HCC44	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.7969318258604616	[312]	[469,633,771,590]	9	hSpCas9	negative selection	6759752
43396846	43396869	7	-	27260156	HCC44	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.388894838837172	[1227]	[1928,1552,2093,1779]	6	hSpCas9	negative selection	6759753
43396835	43396858	7	+	27260156	HCC44	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.006834985989660258	[354]	[316,436,606,275]	0	hSpCas9	negative selection	6824012
43360938	43360961	7	+	27260156	HCC44	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.017568094997360895	[732]	[1141,559,918,810]	0	hSpCas9	negative selection	6824013
43360897	43360920	7	+	27260156	HCC44	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.5649478346310464	[205]	[333,251,442,374]	8	hSpCas9	negative selection	6824014
43479409	43479432	7	+	27260156	HCC44	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.4639845010567751	[880]	[500,215,460,315]	-9	hSpCas9	negative selection	6848540
43320717	43320740	7	+	27260156	G402	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	1.1533968954862788	[41]	[101,40,222,84]	9	hSpCas9	negative selection	6881002
43320639	43320662	7	+	27260156	G402	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.6117925883250042	[312]	[884,618,377,499]	7	hSpCas9	negative selection	6881003
43396846	43396869	7	-	27260156	G402	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5643431800794938	[1227]	[2733,2304,2266,1655]	7	hSpCas9	negative selection	6881004
43396835	43396858	7	+	27260156	G402	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.7745478777432495	[354]	[1090,599,772,548]	8	hSpCas9	negative selection	6945263
43360938	43360961	7	+	27260156	G402	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.1379633448460762	[732]	[1566,802,578,1053]	1	hSpCas9	negative selection	6945264
43360897	43360920	7	+	27260156	G402	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.4272107364578597	[205]	[142,197,248,152]	-5	hSpCas9	negative selection	6945265
43479409	43479432	7	+	27260156	G402	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.4537853151803493	[880]	[593,422,504,91]	-9	hSpCas9	negative selection	6969791
43320717	43320740	7	+	27260156	L33	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.5657063845879531	[41]	[107,27,18,40]	9	hSpCas9	negative selection	7002253
43320639	43320662	7	+	27260156	L33	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.3610944814998021	[312]	[436,163,255,362]	7	hSpCas9	negative selection	7002254
43396846	43396869	7	-	27260156	L33	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.32915920922404074	[1227]	[1428,629,1035,1558]	7	hSpCas9	negative selection	7002255
43396835	43396858	7	+	27260156	L33	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.2450373609566417	[354]	[274,137,150,345]	-5	hSpCas9	negative selection	7066514
43360938	43360961	7	+	27260156	L33	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.13240635688601288	[732]	[820,263,485,972]	3	hSpCas9	negative selection	7066515
43360897	43360920	7	+	27260156	L33	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.026716136348987396	[205]	[253,85,107,171]	0	hSpCas9	negative selection	7066516
43479409	43479432	7	+	27260156	L33	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.1795325851039119	[880]	[575,341,568,800]	-4	hSpCas9	negative selection	7091042
43320717	43320740	7	+	27260156	K562	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.28372818806553557	[41]	[41,15,47,17]	-4	hSpCas9	negative selection	7123504
43320639	43320662	7	+	27260156	K562	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.8866456943432712	[312]	[590,548,498,430]	9	hSpCas9	negative selection	7123505
43396846	43396869	7	-	27260156	K562	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.9055984946261559	[1227]	[1777,1988,2806,1609]	9	hSpCas9	negative selection	7123506
43396835	43396858	7	+	27260156	K562	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.28354864838378474	[354]	[177,306,190,343]	-4	hSpCas9	negative selection	7187765
43360938	43360961	7	+	27260156	K562	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.3666930488794421	[732]	[668,799,1419,487]	4	hSpCas9	negative selection	7187766
43360897	43360920	7	+	27260156	K562	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.1984335918436564	[205]	[166,137,401,132]	2	hSpCas9	negative selection	7187767
43479409	43479432	7	+	27260156	K562	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.657903687155303	[880]	[90,426,290,184]	-9	hSpCas9	negative selection	7212293
43320717	43320740	7	+	27260156	HT29	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.24501039193660246	[41]	[53,67,18,34]	-5	hSpCas9	negative selection	7244755
43320639	43320662	7	+	27260156	HT29	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.4385423237471279	[312]	[475,532,592,461]	8	hSpCas9	negative selection	7244756
43396846	43396869	7	-	27260156	HT29	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5205119282853468	[1227]	[2133,2301,2183,1964]	8	hSpCas9	negative selection	7244757
43396835	43396858	7	+	27260156	HT29	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.295166662986146	[354]	[593,568,514,453]	6	hSpCas9	negative selection	7309016
43360938	43360961	7	+	27260156	HT29	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.2452679721362443	[732]	[1151,1245,1121,757]	5	hSpCas9	negative selection	7309017
43360897	43360920	7	+	27260156	HT29	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.3487079347046552	[205]	[307,176,310,447]	6	hSpCas9	negative selection	7309018
43479409	43479432	7	+	27260156	HT29	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.8133498270089015	[880]	[186,504,238,294]	-9	hSpCas9	negative selection	7333544
43320717	43320740	7	+	27260156	MHHES1	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.20552634555563376	[41]	[14,31,79,33]	-4	hSpCas9	negative selection	7366006
43320639	43320662	7	+	27260156	MHHES1	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.31668526676981024	[312]	[406,593,483,304]	6	hSpCas9	negative selection	7366007
43396846	43396869	7	-	27260156	MHHES1	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.35178174545461505	[1227]	[2473,2111,1186,1439]	6	hSpCas9	negative selection	7366008
43396835	43396858	7	+	27260156	MHHES1	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.20556575311655562	[354]	[309,478,361,257]	-4	hSpCas9	negative selection	7430267
43360938	43360961	7	+	27260156	MHHES1	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.44572478560255735	[732]	[1960,895,960,805]	7	hSpCas9	negative selection	7430268
43360897	43360920	7	+	27260156	MHHES1	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.18254761872513003	[205]	[195,149,297,170]	-3	hSpCas9	negative selection	7430269
43479409	43479432	7	+	27260156	MHHES1	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.997767598112603	[880]	[588,492,507,415]	-9	hSpCas9	negative selection	7454795
43320717	43320740	7	+	27260156	MEWO	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.20311318088025443	[41]	[82,46,12]	4	hSpCas9	negative selection	7487257
43320639	43320662	7	+	27260156	MEWO	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.5384043810189634	[312]	[445,385,447]	9	hSpCas9	negative selection	7487258
43396846	43396869	7	-	27260156	MEWO	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.2831937854062905	[1227]	[1412,1339,1443]	6	hSpCas9	negative selection	7487259
43396835	43396858	7	+	27260156	MEWO	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.4743373608282309	[354]	[319,200,211]	-7	hSpCas9	negative selection	7551518
43360938	43360961	7	+	27260156	MEWO	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.12319001412131103	[732]	[937,653,685]	2	hSpCas9	negative selection	7551519
43360897	43360920	7	+	27260156	MEWO	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.44545373913314634	[205]	[148,141,134]	-7	hSpCas9	negative selection	7551520
43479409	43479432	7	+	27260156	MEWO	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.6870292441004341	[880]	[521,654,359]	-8	hSpCas9	negative selection	7576046
43320717	43320740	7	+	27260156	LNCAPCLONEFGC	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.9273500982414058	[41]	[28,31,12,3]	-8	hSpCas9	negative selection	7608508
43320639	43320662	7	+	27260156	LNCAPCLONEFGC	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.7874269461678924	[312]	[537,458,534,432]	9	hSpCas9	negative selection	7608509
43396846	43396869	7	-	27260156	LNCAPCLONEFGC	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.48542235466766925	[1227]	[1451,1483,1865,1478]	7	hSpCas9	negative selection	7608510
43396835	43396858	7	+	27260156	LNCAPCLONEFGC	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.052920086502722674	[354]	[444,194,250,344]	-1	hSpCas9	negative selection	7672769
43360938	43360961	7	+	27260156	LNCAPCLONEFGC	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.17539695611354178	[732]	[520,511,743,603]	-3	hSpCas9	negative selection	7672770
43360897	43360920	7	+	27260156	LNCAPCLONEFGC	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.0940759535151876	[205]	[114,203,171,206]	-1	hSpCas9	negative selection	7672771
43479409	43479432	7	+	27260156	LNCAPCLONEFGC	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.6140216947771744	[880]	[204,233,337,279]	-9	hSpCas9	negative selection	7697297
43320717	43320740	7	+	27260156	PANC0327	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.7645867137737454	[41]	[53,46,129,23]	9	hSpCas9	negative selection	7729759
43320639	43320662	7	+	27260156	PANC0327	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.6061971713419858	[312]	[423,423,500,343]	8	hSpCas9	negative selection	7729760
43396846	43396869	7	-	27260156	PANC0327	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.47101031370056345	[1227]	[1816,1262,1649,1374]	7	hSpCas9	negative selection	7729761
43396835	43396858	7	+	27260156	PANC0327	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.2340885588495948	[354]	[345,675,250,168]	3	hSpCas9	negative selection	7794020
43360938	43360961	7	+	27260156	PANC0327	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.5207333352839792	[732]	[758,1300,1005,608]	7	hSpCas9	negative selection	7794021
43360897	43360920	7	+	27260156	PANC0327	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.5430680107799126	[205]	[76,196,66,147]	-6	hSpCas9	negative selection	7794022
43479409	43479432	7	+	27260156	PANC0327	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.873123230124696	[880]	[269,199,262,127]	-9	hSpCas9	negative selection	7818548
43320717	43320740	7	+	27260156	NCIH2009	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.5712116822533542	[41]	[54,10,55]	-6	hSpCas9	negative selection	7851010
43320639	43320662	7	+	27260156	NCIH2009	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.3323182492272419	[312]	[579,530,545]	4	hSpCas9	negative selection	7851011
43396846	43396869	7	-	27260156	NCIH2009	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.8507894144493116	[1227]	[3553,3115,2697]	9	hSpCas9	negative selection	7851012
43396835	43396858	7	+	27260156	NCIH2009	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.05026471938341115	[354]	[608,497,451]	0	hSpCas9	negative selection	7915271
43360938	43360961	7	+	27260156	NCIH2009	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.08421920028101526	[732]	[1149,1300,812]	1	hSpCas9	negative selection	7915272
43360897	43360920	7	+	27260156	NCIH2009	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.33729648204620455	[205]	[331,152,219]	-4	hSpCas9	negative selection	7915273
43479409	43479432	7	+	27260156	NCIH2009	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-2.263981091302204	[880]	[300,322,151]	-9	hSpCas9	negative selection	7939799
43320717	43320740	7	+	27260156	NCIH1373	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.8491480696814664	[41]	[126,93,99,4]	8	hSpCas9	negative selection	7972261
43320639	43320662	7	+	27260156	NCIH1373	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	1.1614594032171062	[312]	[681,650,888,240]	9	hSpCas9	negative selection	7972262
43396846	43396869	7	-	27260156	NCIH1373	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.30461851113846916	[1227]	[2040,1441,1586,475]	3	hSpCas9	negative selection	7972263
43396835	43396858	7	+	27260156	NCIH1373	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.652757957719845	[354]	[459,138,97,96]	-6	hSpCas9	negative selection	8036522
43360938	43360961	7	+	27260156	NCIH1373	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.3011430466876977	[732]	[541,625,632,225]	-3	hSpCas9	negative selection	8036523
43360897	43360920	7	+	27260156	NCIH1373	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.7419717947736948	[205]	[227,39,138,44]	-6	hSpCas9	negative selection	8036524
43479409	43479432	7	+	27260156	NCIH1373	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.6123475796295117	[880]	[475,378,143,81]	-9	hSpCas9	negative selection	8061050
43320717	43320740	7	+	27260156	PATU8902	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.8053332598561775	[41]	[30,60,10,36]	-6	hSpCas9	negative selection	8093512
43320639	43320662	7	+	27260156	PATU8902	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.8404276021664023	[312]	[816,642,489,1302]	8	hSpCas9	negative selection	8093513
43396846	43396869	7	-	27260156	PATU8902	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.4887886611859624	[1227]	[2678,2679,1753,2663]	5	hSpCas9	negative selection	8093514
43396835	43396858	7	+	27260156	PATU8902	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.2615783437870991	[354]	[582,499,513,815]	2	hSpCas9	negative selection	8157773
43360938	43360961	7	+	27260156	PATU8902	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.5615546523926875	[732]	[947,1052,243,621]	-5	hSpCas9	negative selection	8157774
43360897	43360920	7	+	27260156	PATU8902	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.04246287184471731	[205]	[33,157,446,452]	0	hSpCas9	negative selection	8157775
43479409	43479432	7	+	27260156	PATU8902	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-4.051479619303533	[880]	[91,105,46,54]	-9	hSpCas9	negative selection	8182301
43320717	43320740	7	+	27260156	PANC1	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.39407305172555773	[41]	[60,48,19,56]	6	hSpCas9	negative selection	8214763
43320639	43320662	7	+	27260156	PANC1	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.5035202141506024	[312]	[282,438,425,383]	7	hSpCas9	negative selection	8214764
43396846	43396869	7	-	27260156	PANC1	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5063719290778295	[1227]	[1318,1865,1309,1542]	7	hSpCas9	negative selection	8214765
43396835	43396858	7	+	27260156	PANC1	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.11055708322918717	[354]	[294,331,301,216]	-2	hSpCas9	negative selection	8279024
43360938	43360961	7	+	27260156	PANC1	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.16506039952651524	[732]	[519,843,467,476]	-3	hSpCas9	negative selection	8279025
43360897	43360920	7	+	27260156	PANC1	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.3342727134918141	[205]	[242,152,142,317]	5	hSpCas9	negative selection	8279026
43479409	43479432	7	+	27260156	PANC1	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.4144399464418425	[880]	[283,287,311,252]	-9	hSpCas9	negative selection	8303552
43320717	43320740	7	+	27260156	PANC0813	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	1.1410391748613673	[41]	[162,66,134,76]	9	hSpCas9	negative selection	8336014
43320639	43320662	7	+	27260156	PANC0813	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.4783437356695174	[312]	[482,581,295,673]	7	hSpCas9	negative selection	8336015
43396846	43396869	7	-	27260156	PANC0813	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5769144650159352	[1227]	[2584,1837,2258,1971]	8	hSpCas9	negative selection	8336016
43396835	43396858	7	+	27260156	PANC0813	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.18216741972493394	[354]	[340,456,357,313]	-3	hSpCas9	negative selection	8400275
43360938	43360961	7	+	27260156	PANC0813	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.17644211368744656	[732]	[948,946,1010,980]	3	hSpCas9	negative selection	8400276
43360897	43360920	7	+	27260156	PANC0813	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.14940070553062057	[205]	[146,126,381,210]	-2	hSpCas9	negative selection	8400277
43479409	43479432	7	+	27260156	PANC0813	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.1279913520878129	[880]	[594,423,459,427]	-9	hSpCas9	negative selection	8424803
43320717	43320740	7	+	27260156	RDES	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.6061588620118767	[41]	[78,68,79,60]	8	hSpCas9	negative selection	8457265
43320639	43320662	7	+	27260156	RDES	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.6299661856881664	[312]	[489,490,499,782]	8	hSpCas9	negative selection	8457266
43396846	43396869	7	-	27260156	RDES	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.3752459778518844	[1227]	[1644,1487,1845,2460]	6	hSpCas9	negative selection	8457267
43396835	43396858	7	+	27260156	RDES	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.24716660634905357	[354]	[318,371,319,356]	-4	hSpCas9	negative selection	8521526
43360938	43360961	7	+	27260156	RDES	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.07860411550784219	[732]	[735,504,1067,931]	-1	hSpCas9	negative selection	8521527
43360897	43360920	7	+	27260156	RDES	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.47755637835389275	[205]	[108,173,218,191]	-7	hSpCas9	negative selection	8521528
43479409	43479432	7	+	27260156	RDES	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.9556419884228572	[880]	[492,441,536,631]	-9	hSpCas9	negative selection	8546054
43320717	43320740	7	+	27260156	PC3	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.2838744788109433	[41]	[40,55,59,47]	6	hSpCas9	negative selection	8578516
43320639	43320662	7	+	27260156	PC3	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.2843428442171843	[312]	[230,345,559,488]	6	hSpCas9	negative selection	8578517
43396846	43396869	7	-	27260156	PC3	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.29253071331963576	[1227]	[966,1364,2529,1633]	6	hSpCas9	negative selection	8578518
43396835	43396858	7	+	27260156	PC3	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.14590293891159095	[354]	[215,697,442,244]	3	hSpCas9	negative selection	8642777
43360938	43360961	7	+	27260156	PC3	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.07933654837832815	[732]	[434,682,1082,765]	-2	hSpCas9	negative selection	8642778
43360897	43360920	7	+	27260156	PC3	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.6196849308860619	[205]	[61,95,228,211]	-8	hSpCas9	negative selection	8642779
43479409	43479432	7	+	27260156	PC3	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.3205247384192743	[880]	[557,607,1082,695]	-6	hSpCas9	negative selection	8667305
43320717	43320740	7	+	27260156	PATU8988T	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.2507580078753304	[41]	[72,10,81,20]	4	hSpCas9	negative selection	8699767
43320639	43320662	7	+	27260156	PATU8988T	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.4486333149965055	[312]	[427,527,337,364]	7	hSpCas9	negative selection	8699768
43396846	43396869	7	-	27260156	PATU8988T	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.4132820575558287	[1227]	[1879,1448,1536,1430]	7	hSpCas9	negative selection	8699769
43396835	43396858	7	+	27260156	PATU8988T	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.31586416600434014	[354]	[292,319,220,272]	-5	hSpCas9	negative selection	8764028
43360938	43360961	7	+	27260156	PATU8988T	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.037140867718878146	[732]	[503,799,1023,568]	0	hSpCas9	negative selection	8764029
43360897	43360920	7	+	27260156	PATU8988T	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.2137330013382993	[205]	[136,223,185,388]	3	hSpCas9	negative selection	8764030
43479409	43479432	7	+	27260156	PATU8988T	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.3867880927014786	[880]	[266,469,201,382]	-9	hSpCas9	negative selection	8788556
43320717	43320740	7	+	27260156	T47D	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.3510678658004678	[41]	[23,77,37,109]	7	hSpCas9	negative selection	8821018
43320639	43320662	7	+	27260156	T47D	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.3351613830165429	[312]	[479,370,504,491]	7	hSpCas9	negative selection	8821019
43396846	43396869	7	-	27260156	T47D	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.46655571665710327	[1227]	[2060,1784,1991,2088]	8	hSpCas9	negative selection	8821020
43396835	43396858	7	+	27260156	T47D	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.02753402957747686	[354]	[369,456,362,495]	0	hSpCas9	negative selection	8885279
43360938	43360961	7	+	27260156	T47D	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.2013437264980632	[732]	[730,752,754,729]	-4	hSpCas9	negative selection	8885280
43360897	43360920	7	+	27260156	T47D	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.3751714855593342	[205]	[219,157,192,170]	-7	hSpCas9	negative selection	8885281
43479409	43479432	7	+	27260156	T47D	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.1886574480070526	[880]	[460,431,406,504]	-9	hSpCas9	negative selection	8909807
43320717	43320740	7	+	27260156	SU8686	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.8721988268946723	[41]	[55,58,112,82]	9	hSpCas9	negative selection	8942269
43320639	43320662	7	+	27260156	SU8686	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.4912974894787553	[312]	[420,358,485,498]	7	hSpCas9	negative selection	8942270
43396846	43396869	7	-	27260156	SU8686	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.6579096740132608	[1227]	[1892,1788,2006,2018]	9	hSpCas9	negative selection	8942271
43396835	43396858	7	+	27260156	SU8686	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.043433722364363714	[354]	[355,297,346,473]	0	hSpCas9	negative selection	9006530
43360938	43360961	7	+	27260156	SU8686	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.17849944616469582	[732]	[770,653,1041,855]	3	hSpCas9	negative selection	9006531
43360897	43360920	7	+	27260156	SU8686	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.033434011072668746	[205]	[236,186,237,165]	0	hSpCas9	negative selection	9006532
43479409	43479432	7	+	27260156	SU8686	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-2.048981198353273	[880]	[263,260,169,118]	-9	hSpCas9	negative selection	9031058
43320717	43320740	7	+	27260156	SKES1	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.5077805228793633	[41]	[80,17,103,34]	8	hSpCas9	negative selection	9063520
43320639	43320662	7	+	27260156	SKES1	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.5665515268503819	[312]	[588,528,483,288]	9	hSpCas9	negative selection	9063521
43396846	43396869	7	-	27260156	SKES1	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5018495935496812	[1227]	[1766,1945,1724,1535]	8	hSpCas9	negative selection	9063522
43396835	43396858	7	+	27260156	SKES1	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.16001991918813277	[354]	[468,314,327,459]	3	hSpCas9	negative selection	9127781
43360938	43360961	7	+	27260156	SKES1	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.05129339852969117	[732]	[720,957,696,496]	-1	hSpCas9	negative selection	9127782
43360897	43360920	7	+	27260156	SKES1	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.049579138274209233	[205]	[289,182,227,111]	-1	hSpCas9	negative selection	9127783
43479409	43479432	7	+	27260156	SKES1	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.2562954120084848	[880]	[991,784,546,663]	-5	hSpCas9	negative selection	9152309
43320717	43320740	7	+	27260156	TOV112D	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	-0.08229341786750188	[41]	[38,24,44,45]	-1	hSpCas9	negative selection	9184771
43320639	43320662	7	+	27260156	TOV112D	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.46956803263952723	[312]	[430,557,420,357]	8	hSpCas9	negative selection	9184772
43396846	43396869	7	-	27260156	TOV112D	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.5249572671392895	[1227]	[1732,2181,1444,1812]	8	hSpCas9	negative selection	9184773
43396835	43396858	7	+	27260156	TOV112D	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	0.15735174923945175	[354]	[593,345,338,312]	3	hSpCas9	negative selection	9249032
43360938	43360961	7	+	27260156	TOV112D	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.09100122201859373	[732]	[725,972,587,878]	1	hSpCas9	negative selection	9249033
43360897	43360920	7	+	27260156	TOV112D	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.26060902027961896	[205]	[121,207,111,248]	-5	hSpCas9	negative selection	9249034
43479409	43479432	7	+	27260156	TOV112D	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.5040778379656916	[880]	[625,842,548,526]	-7	hSpCas9	negative selection	9273560
43320717	43320740	7	+	27260156	TC71	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.5657735914691306	[41]	[68,75,53,67]	9	hSpCas9	negative selection	9306022
43320639	43320662	7	+	27260156	TC71	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.5288549565001911	[312]	[589,463,355,530]	9	hSpCas9	negative selection	9306023
43396846	43396869	7	-	27260156	TC71	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.32520768451168025	[1227]	[1511,1680,1695,1712]	7	hSpCas9	negative selection	9306024
43396835	43396858	7	+	27260156	TC71	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.1439822230942897	[354]	[345,306,332,394]	-4	hSpCas9	negative selection	9370283
43360938	43360961	7	+	27260156	TC71	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	-0.0006577883307571364	[732]	[827,757,689,872]	0	hSpCas9	negative selection	9370284
43360897	43360920	7	+	27260156	TC71	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	0.17387261913360352	[205]	[173,191,346,283]	4	hSpCas9	negative selection	9370285
43479409	43479432	7	+	27260156	TC71	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-0.35868961333036053	[880]	[778,683,741,739]	-7	hSpCas9	negative selection	9394811
43320717	43320740	7	+	27260156	TC32	viability	CGATGCCAGCTCGTACTTTGTGG	HECW1	ENSG00000002746	0.7432056199437533	[41]	[63,74,68,47]	9	hSpCas9	negative selection	9427273
43320639	43320662	7	+	27260156	TC32	viability	GGTCTTGTCCGAAAACTTTCTGG	HECW1	ENSG00000002746	0.7239422920302335	[312]	[346,575,551,426]	9	hSpCas9	negative selection	9427274
43396846	43396869	7	-	27260156	TC32	viability	GCCTCCGACTTCCTTGTCCTTGG	HECW1	ENSG00000002746	0.6532440942602409	[1227]	[1523,1617,2060,2114]	9	hSpCas9	negative selection	9427275
43396835	43396858	7	+	27260156	TC32	viability	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.1304171925716861	[354]	[284,174,449,372]	-2	hSpCas9	negative selection	9491534
43360938	43360961	7	+	27260156	TC32	viability	AGCAACCACCCCCAGTGTCACGG	HECW1	ENSG00000002746	0.01257726544905935	[732]	[665,450,886,874]	0	hSpCas9	negative selection	9491535
43360897	43360920	7	+	27260156	TC32	viability	ATCTGCTTCAAATACTACCATGG	HECW1	ENSG00000002746	-0.11566911487649678	[205]	[174,138,273,145]	-2	hSpCas9	negative selection	9491536
43479409	43479432	7	+	27260156	TC32	viability	TCACCTCCTGCTGTGCAGCCAAG	HECW1	ENSG00000002746	-1.1982452479266543	[880]	[309,259,509,415]	-9	hSpCas9	negative selection	9516062
43311925	43311948	7	-	27869803	HPAFII	viability after 27 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.06492262467620424	[854]	[402,451,NaN]	0	hSpCas9	negative selection	9599550
43396835	43396858	7	+	27869803	HPAFII	viability after 27 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.7506651752287918	[150]	[20,68,NaN]	-5	hSpCas9	negative selection	9599551
43407661	43407684	7	+	27869803	HPAFII	viability after 27 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.28425239527445856	[461]	[313,103,NaN]	-2	hSpCas9	negative selection	9599552
43438019	43438042	7	-	27869803	HPAFII	viability after 27 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.4076072938033557	[583]	[481,344,NaN]	3	hSpCas9	negative selection	9599553
43442540	43442563	7	+	27869803	HPAFII	viability after 27 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.6190202208590316	[270]	[238,201,NaN]	5	hSpCas9	negative selection	9599554
43311925	43311948	7	-	27869803	HPAFII	viability after 15 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.3401749411803363	[854]	[826,662,NaN]	-4	hSpCas9	negative selection	9681999
43396835	43396858	7	+	27869803	HPAFII	viability after 15 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.29505275255081864	[150]	[151,119,NaN]	-3	hSpCas9	negative selection	9682000
43407661	43407684	7	+	27869803	HPAFII	viability after 15 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	0.011258460013991778	[461]	[833,292,NaN]	0	hSpCas9	negative selection	9682001
43438019	43438042	7	-	27869803	HPAFII	viability after 15 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	-0.06576628672787477	[583]	[841,448,NaN]	0	hSpCas9	negative selection	9682002
43442540	43442563	7	+	27869803	HPAFII	viability after 15 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.23771642611434146	[270]	[401,306,NaN]	2	hSpCas9	negative selection	9682003
43311925	43311948	7	-	27869803	ASPC1	viability after 36 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.6459999978185254	[2348]	[923,2283,726]	6	hSpCas9	negative selection	9764448
43396835	43396858	7	+	27869803	ASPC1	viability after 36 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.4485578369037224	[208]	[75,11,69]	-4	hSpCas9	negative selection	9764449
43407661	43407684	7	+	27869803	ASPC1	viability after 36 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	0.9442420921645412	[798]	[147,1213,265]	8	hSpCas9	negative selection	9764450
43438019	43438042	7	-	27869803	ASPC1	viability after 36 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	1.1692874774809434	[1185]	[902,1633,382]	9	hSpCas9	negative selection	9764451
43442540	43442563	7	+	27869803	ASPC1	viability after 36 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	-0.2965166283600618	[895]	[459,309,63]	-3	hSpCas9	negative selection	9764452
43311925	43311948	7	-	27869803	PATU8988S	viability after 35 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.024111760071634958	[1892]	[648,850,NaN]	0	hSpCas9	negative selection	9846897
43396835	43396858	7	+	27869803	PATU8988S	viability after 35 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.0831190451308732	[229]	[63,110,NaN]	-1	hSpCas9	negative selection	9846898
43407661	43407684	7	+	27869803	PATU8988S	viability after 35 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.01609305152897611	[668]	[244,287,NaN]	0	hSpCas9	negative selection	9846899
43438019	43438042	7	-	27869803	PATU8988S	viability after 35 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.14493367723457917	[974]	[293,574,NaN]	1	hSpCas9	negative selection	9846900
43442540	43442563	7	+	27869803	PATU8988S	viability after 35 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.12269181210494251	[649]	[295,273,NaN]	1	hSpCas9	negative selection	9846901
43311925	43311948	7	-	27869803	PATU8988S	viability after 31 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	0.2594417876492203	[1892]	[577,1317,NaN]	3	hSpCas9	negative selection	9929346
43396835	43396858	7	+	27869803	PATU8988S	viability after 31 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.2591355112079454	[229]	[40,121,NaN]	-3	hSpCas9	negative selection	9929347
43407661	43407684	7	+	27869803	PATU8988S	viability after 31 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.0006364724142391975	[668]	[274,255,NaN]	0	hSpCas9	negative selection	9929348
43438019	43438042	7	-	27869803	PATU8988S	viability after 31 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.2762640638197301	[974]	[410,546,NaN]	3	hSpCas9	negative selection	9929349
43442540	43442563	7	+	27869803	PATU8988S	viability after 31 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.16499913313684422	[649]	[228,368,NaN]	2	hSpCas9	negative selection	9929350
43311925	43311948	7	-	27869803	HPAFII	viability after 35 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.013842177223253094	[854]	[431,424,NaN]	0	hSpCas9	negative selection	10011795
43396835	43396858	7	+	27869803	HPAFII	viability after 35 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-1.1342197099767066	[150]	[39,28,NaN]	-6	hSpCas9	negative selection	10011796
43407661	43407684	7	+	27869803	HPAFII	viability after 35 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.4798570049355942	[461]	[170,163,NaN]	-3	hSpCas9	negative selection	10011797
43438019	43438042	7	-	27869803	HPAFII	viability after 35 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	0.49868152165575763	[583]	[460,368,NaN]	3	hSpCas9	negative selection	10011798
43442540	43442563	7	+	27869803	HPAFII	viability after 35 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.5034632399626796	[270]	[225,158,NaN]	3	hSpCas9	negative selection	10011799
43311925	43311948	7	-	27869803	HPAFII	viability after 31 days	TCAGTGTCGCTGGTGGAGCGGGG	HECW1	ENSG00000002746	-0.020364496552554012	[854]	[430,518,NaN]	0	hSpCas9	negative selection	10094244
43396835	43396858	7	+	27869803	HPAFII	viability after 31 days	GATGAGACCGTCCAAGGACAAGG	HECW1	ENSG00000002746	-0.14280443388767006	[150]	[48,106,NaN]	-1	hSpCas9	negative selection	10094245
43407661	43407684	7	+	27869803	HPAFII	viability after 31 days	TCCCTCACCATGGACAGGAGAGG	HECW1	ENSG00000002746	-0.5457740280466733	[461]	[235,113,NaN]	-4	hSpCas9	negative selection	10094246
43438019	43438042	7	-	27869803	HPAFII	viability after 31 days	TTCCAGCACGTCAGTGGGCAAGG	HECW1	ENSG00000002746	-0.05387970982862389	[583]	[320,309,NaN]	0	hSpCas9	negative selection	10094247
43442540	43442563	7	+	27869803	HPAFII	viability after 31 days	TCAGCTACACACTTGGCCGCAGG	HECW1	ENSG00000002746	0.016803719560779737	[270]	[150,156,NaN]	0	hSpCas9	negative selection	10094248
43463727	43463750	7	+	28162770	P31FUJ	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-1.6853144091118855	[103]	[37]	-8	hSpCas9	negative selection	10168196
43444402	43444425	7	+	28162770	P31FUJ	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.4993171789831343	[248]	[206]	-4	hSpCas9	negative selection	10168197
43311797	43311820	7	-	28162770	P31FUJ	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	-0.06534545856281596	[194]	[218]	0	hSpCas9	negative selection	10168198
43311815	43311838	7	+	28162770	P31FUJ	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.7329820802477083	[63]	[124]	8	hSpCas9	negative selection	10168199
43311847	43311870	7	-	28162770	P31FUJ	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.7174447603885219	[58]	[113]	7	hSpCas9	negative selection	10168200
43311932	43311955	7	-	28162770	P31FUJ	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.01471920204809063	[186]	[221]	0	hSpCas9	negative selection	10168201
43311971	43311994	7	-	28162770	P31FUJ	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.2817709684153795	[272]	[389]	3	hSpCas9	negative selection	10168202
43312001	43312024	7	-	28162770	P31FUJ	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.9745860532583203	[358]	[828]	9	hSpCas9	negative selection	10168203
43444283	43444306	7	+	28162770	P31FUJ	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	0.1297678749703297	[48]	[62]	1	hSpCas9	negative selection	10168204
43444361	43444384	7	+	28162770	P31FUJ	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.5002825152793646	[194]	[161]	-4	hSpCas9	negative selection	10168205
43463727	43463750	7	+	28162770	TF1	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10337562
43444402	43444425	7	+	28162770	TF1	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10337563
43311797	43311820	7	-	28162770	TF1	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	NaN	[NaN]	[281]	1	hSpCas9	negative selection	10337564
43311815	43311838	7	+	28162770	TF1	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	NaN	[NaN]	[50]	1	hSpCas9	negative selection	10337565
43311847	43311870	7	-	28162770	TF1	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	NaN	[NaN]	[11]	1	hSpCas9	negative selection	10337566
43311932	43311955	7	-	28162770	TF1	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10337567
43311971	43311994	7	-	28162770	TF1	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	NaN	[NaN]	[168]	1	hSpCas9	negative selection	10337568
43312001	43312024	7	-	28162770	TF1	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	NaN	[NaN]	[204]	1	hSpCas9	negative selection	10337569
43444283	43444306	7	+	28162770	TF1	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	NaN	[NaN]	[67]	1	hSpCas9	negative selection	10337570
43444361	43444384	7	+	28162770	TF1	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10337571
43463727	43463750	7	+	28162770	SKM1	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-1.6293566200796095	[27]	[15]	-8	hSpCas9	negative selection	10506928
43444402	43444425	7	+	28162770	SKM1	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.31676638977158367	[61]	[87]	-3	hSpCas9	negative selection	10506929
43311797	43311820	7	-	28162770	SKM1	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	-0.16992500144231237	[62]	[98]	-1	hSpCas9	negative selection	10506930
43311815	43311838	7	+	28162770	SKM1	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.38235680048418097	[22]	[52]	4	hSpCas9	negative selection	10506931
43311847	43311870	7	-	28162770	SKM1	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.02553509210713778	[18]	[32]	0	hSpCas9	negative selection	10506932
43311932	43311955	7	-	28162770	SKM1	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	-0.14822993034299337	[41]	[66]	-1	hSpCas9	negative selection	10506933
43311971	43311994	7	-	28162770	SKM1	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.1129032737561097	[67]	[129]	1	hSpCas9	negative selection	10506934
43312001	43312024	7	-	28162770	SKM1	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	1.3165591325109718	[61]	[272]	9	hSpCas9	negative selection	10506935
43444283	43444306	7	+	28162770	SKM1	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	1.8884916847830095	[10]	[71]	9	hSpCas9	negative selection	10506936
43444361	43444384	7	+	28162770	SKM1	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.9512847149669718	[34]	[31]	-6	hSpCas9	negative selection	10506937
43463727	43463750	7	+	28162770	SKM1	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-1.6293566200796095	[27]	[15]	-8	hSpCas9	negative selection	10676294
43444402	43444425	7	+	28162770	SKM1	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.31676638977158367	[61]	[87]	-3	hSpCas9	negative selection	10676295
43311797	43311820	7	-	28162770	SKM1	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	-0.16992500144231237	[62]	[98]	-1	hSpCas9	negative selection	10676296
43311815	43311838	7	+	28162770	SKM1	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.38235680048418097	[22]	[52]	4	hSpCas9	negative selection	10676297
43311847	43311870	7	-	28162770	SKM1	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.02553509210713778	[18]	[32]	0	hSpCas9	negative selection	10676298
43311932	43311955	7	-	28162770	SKM1	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	-0.14822993034299337	[41]	[66]	-1	hSpCas9	negative selection	10676299
43311971	43311994	7	-	28162770	SKM1	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.1129032737561097	[67]	[129]	1	hSpCas9	negative selection	10676300
43312001	43312024	7	-	28162770	SKM1	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	1.3165591325109718	[61]	[272]	9	hSpCas9	negative selection	10676301
43444283	43444306	7	+	28162770	SKM1	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	1.8884916847830095	[10]	[71]	9	hSpCas9	negative selection	10676302
43444361	43444384	7	+	28162770	SKM1	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.9512847149669718	[34]	[31]	-6	hSpCas9	negative selection	10676303
43463727	43463750	7	+	28162770	PL21	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	0.4440651973754094	[75]	[44]	4	hSpCas9	negative selection	10845660
43444402	43444425	7	+	28162770	PL21	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.40754296273191953	[191]	[62]	-3	hSpCas9	negative selection	10845661
43311797	43311820	7	-	28162770	PL21	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.1865930826513724	[213]	[105]	1	hSpCas9	negative selection	10845662
43311815	43311838	7	+	28162770	PL21	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.7851021152104765	[43]	[32]	6	hSpCas9	negative selection	10845663
43311847	43311870	7	-	28162770	PL21	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-1.6299353840683677	[63]	[8]	-8	hSpCas9	negative selection	10845664
43311932	43311955	7	-	28162770	PL21	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	-0.5150216093585377	[196]	[59]	-4	hSpCas9	negative selection	10845665
43311971	43311994	7	-	28162770	PL21	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.6899448821701362	[187]	[131]	6	hSpCas9	negative selection	10845666
43312001	43312024	7	-	28162770	PL21	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	-0.2609942993789776	[211]	[76]	-2	hSpCas9	negative selection	10845667
43444283	43444306	7	+	28162770	PL21	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	2.785102115210476	[25]	[77]	9	hSpCas9	negative selection	10845668
43444361	43444384	7	+	28162770	PL21	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.4455769173109322	[96]	[30]	-3	hSpCas9	negative selection	10845669
43463727	43463750	7	+	28162770	P31FUJ	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-1.6853144091118855	[103]	[37]	-8	hSpCas9	negative selection	11015026
43444402	43444425	7	+	28162770	P31FUJ	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.4993171789831343	[248]	[206]	-4	hSpCas9	negative selection	11015027
43311797	43311820	7	-	28162770	P31FUJ	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	-0.06534545856281596	[194]	[218]	0	hSpCas9	negative selection	11015028
43311815	43311838	7	+	28162770	P31FUJ	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.7329820802477083	[63]	[124]	8	hSpCas9	negative selection	11015029
43311847	43311870	7	-	28162770	P31FUJ	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.7174447603885219	[58]	[113]	7	hSpCas9	negative selection	11015030
43311932	43311955	7	-	28162770	P31FUJ	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.01471920204809063	[186]	[221]	0	hSpCas9	negative selection	11015031
43311971	43311994	7	-	28162770	P31FUJ	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.2817709684153795	[272]	[389]	3	hSpCas9	negative selection	11015032
43312001	43312024	7	-	28162770	P31FUJ	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.9745860532583203	[358]	[828]	9	hSpCas9	negative selection	11015033
43444283	43444306	7	+	28162770	P31FUJ	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	0.1297678749703297	[48]	[62]	1	hSpCas9	negative selection	11015034
43444361	43444384	7	+	28162770	P31FUJ	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.5002825152793646	[194]	[161]	-4	hSpCas9	negative selection	11015035
43463727	43463750	7	+	28162770	OCIAML5	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	1.147933429136003	[17]	[71]	8	hSpCas9	negative selection	11184392
43444402	43444425	7	+	28162770	OCIAML5	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	0.9449464069721482	[119]	[416]	7	hSpCas9	negative selection	11184393
43311797	43311820	7	-	28162770	OCIAML5	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.77431585723714	[102]	[317]	6	hSpCas9	negative selection	11184394
43311815	43311838	7	+	28162770	OCIAML5	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	1.3736462087640624	[30]	[144]	9	hSpCas9	negative selection	11184395
43311847	43311870	7	-	28162770	OCIAML5	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	1.0713121475330907	[28]	[109]	8	hSpCas9	negative selection	11184396
43311932	43311955	7	-	28162770	OCIAML5	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.2435110891182341	[72]	[155]	2	hSpCas9	negative selection	11184397
43311971	43311994	7	-	28162770	OCIAML5	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.7366190158998767	[128]	[387]	6	hSpCas9	negative selection	11184398
43312001	43312024	7	-	28162770	OCIAML5	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.8897647784740252	[147]	[494]	7	hSpCas9	negative selection	11184399
43444283	43444306	7	+	28162770	OCIAML5	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	2.0778549933998627	[28]	[220]	9	hSpCas9	negative selection	11184400
43444361	43444384	7	+	28162770	OCIAML5	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-1.3130403543096998	[116]	[84]	-6	hSpCas9	negative selection	11184401
43463727	43463750	7	+	28162770	EOL1	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-0.8883666758289703	[129]	[36]	-6	hSpCas9	negative selection	11353758
43444402	43444425	7	+	28162770	EOL1	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.7588184332116161	[272]	[84]	-5	hSpCas9	negative selection	11353759
43311797	43311820	7	-	28162770	EOL1	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.19183165040568612	[338]	[203]	1	hSpCas9	negative selection	11353760
43311815	43311838	7	+	28162770	EOL1	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	-0.5957090397628062	[108]	[37]	-4	hSpCas9	negative selection	11353761
43311847	43311870	7	-	28162770	EOL1	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-3.4259494755135984	[101]	[4]	-9	hSpCas9	negative selection	11353762
43311932	43311955	7	-	28162770	EOL1	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.6560589356446328	[317]	[263]	6	hSpCas9	negative selection	11353763
43311971	43311994	7	-	28162770	EOL1	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	-0.21397209251089327	[283]	[128]	-2	hSpCas9	negative selection	11353764
43312001	43312024	7	-	28162770	EOL1	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.07840522907665662	[310]	[172]	0	hSpCas9	negative selection	11353765
43444283	43444306	7	+	28162770	EOL1	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	-1.837952914702809	[94]	[13]	-8	hSpCas9	negative selection	11353766
43444361	43444384	7	+	28162770	EOL1	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-1.0965138439572952	[206]	[50]	-6	hSpCas9	negative selection	11353767
43463727	43463750	7	+	28162770	MOLM13	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	0.709862171850543	[114]	[135]	5	hSpCas9	negative selection	11523124
43444402	43444425	7	+	28162770	MOLM13	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	0.25970345270640494	[319]	[276]	1	hSpCas9	negative selection	11523125
43311797	43311820	7	-	28162770	MOLM13	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.5486206536574357	[277]	[293]	4	hSpCas9	negative selection	11523126
43311815	43311838	7	+	28162770	MOLM13	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.036550069936634344	[88]	[65]	0	hSpCas9	negative selection	11523127
43311847	43311870	7	-	28162770	MOLM13	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	0.6122792908797534	[75]	[83]	4	hSpCas9	negative selection	11523128
43311932	43311955	7	-	28162770	MOLM13	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.4622428184034368	[255]	[254]	3	hSpCas9	negative selection	11523129
43311971	43311994	7	-	28162770	MOLM13	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.2205416129514267	[310]	[261]	1	hSpCas9	negative selection	11523130
43312001	43312024	7	-	28162770	MOLM13	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	-0.41305794681165764	[371]	[201]	-2	hSpCas9	negative selection	11523131
43444283	43444306	7	+	28162770	MOLM13	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	0.2322611330514368	[72]	[61]	1	hSpCas9	negative selection	11523132
43444361	43444384	7	+	28162770	MOLM13	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-1.2554012757245507	[174]	[52]	-6	hSpCas9	negative selection	11523133
43463727	43463750	7	+	28162770	HEL	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	0.8271634031377844	[87]	[99]	7	hSpCas9	negative selection	11692490
43444402	43444425	7	+	28162770	HEL	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	0.6013980366194573	[176]	[171]	5	hSpCas9	negative selection	11692491
43311797	43311820	7	-	28162770	HEL	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	1.0087595110708898	[231]	[298]	8	hSpCas9	negative selection	11692492
43311815	43311838	7	+	28162770	HEL	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	1.1305326737145147	[86]	[121]	8	hSpCas9	negative selection	11692493
43311847	43311870	7	-	28162770	HEL	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.1854948197331634	[86]	[48]	-1	hSpCas9	negative selection	11692494
43311932	43311955	7	-	28162770	HEL	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	1.333141539023714	[232]	[375]	9	hSpCas9	negative selection	11692495
43311971	43311994	7	-	28162770	HEL	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.0006952360719333361	[347]	[222]	0	hSpCas9	negative selection	11692496
43312001	43312024	7	-	28162770	HEL	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.8376842479919815	[234]	[268]	7	hSpCas9	negative selection	11692497
43444283	43444306	7	+	28162770	HEL	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	-2.387008511393695	[48]	[5]	-8	hSpCas9	negative selection	11692498
43444361	43444384	7	+	28162770	HEL	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.922045786783169	[141]	[47]	-5	hSpCas9	negative selection	11692499
43463727	43463750	7	+	28162770	MV411	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	0.2869659149694126	[71]	[73]	2	hSpCas9	negative selection	11861856
43444402	43444425	7	+	28162770	MV411	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	0.7779522674815552	[179]	[259]	7	hSpCas9	negative selection	11861857
43311797	43311820	7	-	28162770	MV411	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.8581631475690131	[147]	[225]	7	hSpCas9	negative selection	11861858
43311815	43311838	7	+	28162770	MV411	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.3405469551742567	[89]	[95]	3	hSpCas9	negative selection	11861859
43311847	43311870	7	-	28162770	MV411	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.0025407022255723444	[87]	[73]	0	hSpCas9	negative selection	11861860
43311932	43311955	7	-	28162770	MV411	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	-1.050530645160406	[208]	[84]	-6	hSpCas9	negative selection	11861861
43311971	43311994	7	-	28162770	MV411	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	-0.37355325912259496	[222]	[144]	-3	hSpCas9	negative selection	11861862
43312001	43312024	7	-	28162770	MV411	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.5304466563778352	[262]	[319]	5	hSpCas9	negative selection	11861863
43444283	43444306	7	+	28162770	MV411	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	0.776546816770414	[78]	[113]	7	hSpCas9	negative selection	11861864
43444361	43444384	7	+	28162770	MV411	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-1.1362667416912768	[166]	[63]	-6	hSpCas9	negative selection	11861865
43463727	43463750	7	+	28162770	MONOMAC1	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-1.4100305703937521	[50]	[21]	-8	hSpCas9	negative selection	12031222
43444402	43444425	7	+	28162770	MONOMAC1	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	1.1002291935935395	[117]	[289]	8	hSpCas9	negative selection	12031223
43311797	43311820	7	-	28162770	MONOMAC1	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.5969596921430316	[123]	[214]	6	hSpCas9	negative selection	12031224
43311815	43311838	7	+	28162770	MONOMAC1	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.17493193032740417	[33]	[43]	1	hSpCas9	negative selection	12031225
43311847	43311870	7	-	28162770	MONOMAC1	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.33454037080948873	[32]	[29]	-3	hSpCas9	negative selection	12031226
43311932	43311955	7	-	28162770	MONOMAC1	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	-0.08780777730479539	[88]	[95]	-1	hSpCas9	negative selection	12031227
43311971	43311994	7	-	28162770	MONOMAC1	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.9136072166244389	[137]	[297]	8	hSpCas9	negative selection	12031228
43312001	43312024	7	-	28162770	MONOMAC1	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.37750903771626404	[138]	[206]	4	hSpCas9	negative selection	12031229
43444283	43444306	7	+	28162770	MONOMAC1	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	0.9438256887802959	[38]	[85]	8	hSpCas9	negative selection	12031230
43444361	43444384	7	+	28162770	MONOMAC1	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.7542543572978055	[102]	[69]	-6	hSpCas9	negative selection	12031231
43463727	43463750	7	+	28162770	OCIAML2	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	-0.4035156293836243	[20]	[87]	-3	hSpCas9	negative selection	12200588
43444402	43444425	7	+	28162770	OCIAML2	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.49726495174562796	[40]	[160]	-4	hSpCas9	negative selection	12200589
43311797	43311820	7	-	28162770	OCIAML2	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.6212926641988782	[37]	[323]	6	hSpCas9	negative selection	12200590
43311815	43311838	7	+	28162770	OCIAML2	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	0.8869221793759225	[15]	[163]	8	hSpCas9	negative selection	12200591
43311847	43311870	7	-	28162770	OCIAML2	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.7825738315569013	[17]	[57]	-5	hSpCas9	negative selection	12200592
43311932	43311955	7	-	28162770	OCIAML2	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.020510653122474132	[44]	[252]	0	hSpCas9	negative selection	12200593
43311971	43311994	7	-	28162770	OCIAML2	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.3909866906019167	[40]	[297]	4	hSpCas9	negative selection	12200594
43312001	43312024	7	-	28162770	OCIAML2	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.5865655763393816	[33]	[282]	6	hSpCas9	negative selection	12200595
43444283	43444306	7	+	28162770	OCIAML2	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	-0.3237884369128905	[13]	[61]	-3	hSpCas9	negative selection	12200596
43444361	43444384	7	+	28162770	OCIAML2	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	0.13271120479384946	[12]	[78]	1	hSpCas9	negative selection	12200597
43463727	43463750	7	+	28162770	OCIAML3	viability	GAGCAAGCCCCAGCAGGAGGAGG	HECW1	ENSG00000002746	0.8914191868460783	[9]	[55]	7	hSpCas9	negative selection	12369954
43444402	43444425	7	+	28162770	OCIAML3	viability	AGAGCTTTCCAGACCAGCTGAGG	HECW1	ENSG00000002746	-0.29334816219045223	[40]	[100]	-2	hSpCas9	negative selection	12369955
43311797	43311820	7	-	28162770	OCIAML3	viability	GTTTCTAGAAGGAGACGCCATGG	HECW1	ENSG00000002746	0.7220198531235148	[48]	[243]	6	hSpCas9	negative selection	12369956
43311815	43311838	7	+	28162770	OCIAML3	viability	GAAACTCCCAGAGCCGACGCCGG	HECW1	ENSG00000002746	-2.387556762856737	[25]	[14]	-9	hSpCas9	negative selection	12369957
43311847	43311870	7	-	28162770	OCIAML3	viability	GGGTTGTAGCTGTATCGGAGCGG	HECW1	ENSG00000002746	-0.20169021754540273	[15]	[41]	-1	hSpCas9	negative selection	12369958
43311932	43311955	7	-	28162770	OCIAML3	viability	GACCAGGTCAGTGTCGCTGGTGG	HECW1	ENSG00000002746	0.002095418002193372	[42]	[129]	0	hSpCas9	negative selection	12369959
43311971	43311994	7	-	28162770	OCIAML3	viability	GGAGCTGCTGACCATGAGCGTGG	HECW1	ENSG00000002746	0.5177027471728536	[58]	[254]	5	hSpCas9	negative selection	12369960
43312001	43312024	7	-	28162770	OCIAML3	viability	CAGGTCCTGAGAGTGCCCGATGG	HECW1	ENSG00000002746	0.039453378088183055	[77]	[241]	0	hSpCas9	negative selection	12369961
43444283	43444306	7	+	28162770	OCIAML3	viability	AACCTGATGGAAAGCGGCAGTGG	HECW1	ENSG00000002746	1.9024181857953357	[6]	[78]	9	hSpCas9	negative selection	12369962
43444361	43444384	7	+	28162770	OCIAML3	viability	GGTGAGGGCAGTGTCCCCGATGG	HECW1	ENSG00000002746	-0.021117971903582056	[39]	[118]	0	hSpCas9	negative selection	12369963