Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8925
• Symbol:HERC1
• Description:HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

DataSource: http://genomecrispr.dkfz.de/#!/results/HERC1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
63775272	63775295	15	+	26472758	Jiyoye	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	0.9477437628685761	[21]	[31]	6	hSpCas9	negative selection	70197
63727657	63727680	15	-	26472758	Jiyoye	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	-0.11047718425585673	[334]	[233]	-1	hSpCas9	negative selection	70198
63727719	63727742	15	+	26472758	Jiyoye	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	1.5975065936100226	[38]	[88]	8	hSpCas9	negative selection	70199
63716332	63716355	15	-	26472758	Jiyoye	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	1.9921378822270288	[0]	[2]	8	hSpCas9	negative selection	70200
63636003	63636026	15	-	26472758	Jiyoye	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	1.1646050782317952	[41]	[70]	7	hSpCas9	negative selection	70201
63623759	63623782	15	-	26472758	Jiyoye	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.37643093777912173	[240]	[139]	-3	hSpCas9	negative selection	70202
63775554	63775577	15	-	26472758	Jiyoye	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	-0.6677866761753488	[157]	[74]	-5	hSpCas9	negative selection	70203
63764139	63764162	15	-	26472758	Jiyoye	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-2.400179540551731	[27]	[3]	-8	hSpCas9	negative selection	70204
63747055	63747078	15	+	26472758	Jiyoye	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.7352295791900774	[46]	[58]	5	hSpCas9	negative selection	70205
63775272	63775295	15	+	26472758	KBM7	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	0.3629831610207386	[83,201]	[51,124]	4	hSpCas9	negative selection	261315
63727657	63727680	15	-	26472758	KBM7	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.06432646291435318	[991,898]	[374,544]	0	hSpCas9	negative selection	261316
63727719	63727742	15	+	26472758	KBM7	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-0.10554805777119947	[251,305]	[109,135]	-1	hSpCas9	negative selection	261317
63716332	63716355	15	-	26472758	KBM7	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-4.7781499906605545	[96,81]	[0,1]	-9	hSpCas9	negative selection	261318
63636003	63636026	15	-	26472758	KBM7	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	0.06055570139550159	[192,198]	[167,32]	0	hSpCas9	negative selection	261319
63623759	63623782	15	-	26472758	KBM7	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.0007446825546129077	[651,573]	[313,263]	0	hSpCas9	negative selection	261320
63775554	63775577	15	-	26472758	KBM7	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	-0.46935020928488513	[515,633]	[126,261]	-4	hSpCas9	negative selection	261321
63764139	63764162	15	-	26472758	KBM7	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.2408458943336904	[50,48]	[0,17]	-7	hSpCas9	negative selection	261322
63747055	63747078	15	+	26472758	KBM7	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	-0.965885549157078	[211,290]	[55,66]	-6	hSpCas9	negative selection	261323
63775272	63775295	15	+	26472758	Raji	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	0.5527946836959621	[93]	[31]	5	hSpCas9	negative selection	452433
63727657	63727680	15	-	26472758	Raji	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.3597348594402632	[496]	[147]	3	hSpCas9	negative selection	452434
63727719	63727742	15	+	26472758	Raji	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-0.21454455951376294	[134]	[26]	-2	hSpCas9	negative selection	452435
63716332	63716355	15	-	26472758	Raji	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-3.507326308741609	[48]	[0]	-9	hSpCas9	negative selection	452436
63636003	63636026	15	-	26472758	Raji	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	1.1439094113987136	[77]	[39]	8	hSpCas9	negative selection	452437
63623759	63623782	15	-	26472758	Raji	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.33525842529984584	[298]	[54]	-3	hSpCas9	negative selection	452438
63775554	63775577	15	-	26472758	Raji	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.8568400737230025	[206]	[86]	7	hSpCas9	negative selection	452439
63764139	63764162	15	-	26472758	Raji	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-3.5650418065978964	[50]	[0]	-9	hSpCas9	negative selection	452440
63747055	63747078	15	+	26472758	Raji	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.7519028807752105	[86]	[33]	7	hSpCas9	negative selection	452441
63775272	63775295	15	+	26472758	K562	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	0.5157207494838412	[86]	[104]	4	hSpCas9	negative selection	643551
63727657	63727680	15	-	26472758	K562	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.5263679936833496	[782]	[951]	4	hSpCas9	negative selection	643552
63727719	63727742	15	+	26472758	K562	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-0.33200709110022386	[336]	[225]	-2	hSpCas9	negative selection	643553
63716332	63716355	15	-	26472758	K562	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-5.777949085362007	[64]	[0]	-9	hSpCas9	negative selection	643554
63636003	63636026	15	-	26472758	K562	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	0.9362964323041152	[103]	[167]	7	hSpCas9	negative selection	643555
63623759	63623782	15	-	26472758	K562	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.5604205964723744	[572]	[327]	-4	hSpCas9	negative selection	643556
63775554	63775577	15	-	26472758	K562	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	-0.10535300014622878	[496]	[389]	0	hSpCas9	negative selection	643557
63764139	63764162	15	-	26472758	K562	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.15694383471532047	[69]	[52]	-1	hSpCas9	negative selection	643558
63747055	63747078	15	+	26472758	K562	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.5575766129260773	[98]	[122]	4	hSpCas9	negative selection	643559
63747013	63747036	15	+	26627737	DLD1	viability	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.07144122872919179	[653]	[186,149,237]	0	hSpCas9	negative selection	791249
63749475	63749498	15	-	26627737	DLD1	viability	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	1.209132121237967	[192]	[209,151,67]	9	hSpCas9	negative selection	791250
63756681	63756704	15	-	26627737	DLD1	viability	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.20315409467092171	[902]	[279,272,191]	-2	hSpCas9	negative selection	791251
63758277	63758300	15	+	26627737	DLD1	viability	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.5257382774602317	[793]	[305,344,411]	5	hSpCas9	negative selection	791252
63764139	63764162	15	-	26627737	DLD1	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	1.728060069393665	[49]	[110,32,15]	9	hSpCas9	negative selection	791253
63775052	63775075	15	+	26627737	DLD1	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.5589673814378298	[725]	[148,162,150]	-5	hSpCas9	negative selection	791254
63747013	63747036	15	+	26627737	GBM cells	viability after 5 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.812036424205719	[230]	[228,205]	9	hSpCas9	negative selection	873564
63749475	63749498	15	-	26627737	GBM cells	viability after 5 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.9473767097188612	[168]	[46,46]	-9	hSpCas9	negative selection	873565
63756681	63756704	15	-	26627737	GBM cells	viability after 5 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.055883221224084845	[434]	[257,226]	0	hSpCas9	negative selection	873566
63758277	63758300	15	+	26627737	GBM cells	viability after 5 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.31395137416452945	[566]	[406,348]	5	hSpCas9	negative selection	873567
63764139	63764162	15	-	26627737	GBM cells	viability after 5 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.474303448698531	[135]	[53,50]	-6	hSpCas9	negative selection	873568
63775052	63775075	15	+	26627737	GBM cells	viability after 5 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.27699361816585977	[256]	[158,174]	4	hSpCas9	negative selection	873569
63747013	63747036	15	+	26627737	GBM cells	viability after 13 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.7824395179426373	[230]	[278,163]	8	hSpCas9	negative selection	955879
63749475	63749498	15	-	26627737	GBM cells	viability after 13 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.4094833612390484	[168]	[73,64]	-5	hSpCas9	negative selection	955880
63756681	63756704	15	-	26627737	GBM cells	viability after 13 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.06254625936493063	[434]	[235,254]	0	hSpCas9	negative selection	955881
63758277	63758300	15	+	26627737	GBM cells	viability after 13 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.37575449700975616	[566]	[466,343]	5	hSpCas9	negative selection	955882
63764139	63764162	15	-	26627737	GBM cells	viability after 13 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.17826682772381763	[135]	[78,53]	-2	hSpCas9	negative selection	955883
63775052	63775075	15	+	26627737	GBM cells	viability after 13 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.18180270678479615	[256]	[225,102]	2	hSpCas9	negative selection	955884
63747013	63747036	15	+	26627737	GBM cells	viability after 21 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.27799280746266686	[230]	[159,144]	3	hSpCas9	negative selection	1038194
63749475	63749498	15	-	26627737	GBM cells	viability after 21 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.7906100715249349	[168]	[62,43]	-6	hSpCas9	negative selection	1038195
63756681	63756704	15	-	26627737	GBM cells	viability after 21 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.3883392897595655	[434]	[190,170]	-4	hSpCas9	negative selection	1038196
63758277	63758300	15	+	26627737	GBM cells	viability after 21 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.09375355298113108	[566]	[346,311]	1	hSpCas9	negative selection	1038197
63764139	63764162	15	-	26627737	GBM cells	viability after 21 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.6343398732140998	[135]	[56,38]	-5	hSpCas9	negative selection	1038198
63775052	63775075	15	+	26627737	GBM cells	viability after 21 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.7101659116114092	[256]	[88,81]	-6	hSpCas9	negative selection	1038199
63747013	63747036	15	+	26627737	RPE1	viability after 9 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.45114962493930555	[1529]	[221,515]	-3	hSpCas9	negative selection	1120509
63749475	63749498	15	-	26627737	RPE1	viability after 9 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.5272357028803228	[856]	[83,317]	-4	hSpCas9	negative selection	1120510
63756681	63756704	15	-	26627737	RPE1	viability after 9 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.24999292239056348	[1547]	[395,808]	1	hSpCas9	negative selection	1120511
63758277	63758300	15	+	26627737	RPE1	viability after 9 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.26243296459889565	[2253]	[814,886]	1	hSpCas9	negative selection	1120512
63764139	63764162	15	-	26627737	RPE1	viability after 9 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.0815302720294548	[454]	[65,68]	-7	hSpCas9	negative selection	1120513
63775052	63775075	15	+	26627737	RPE1	viability after 9 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.41831643823853243	[1359]	[277,370]	-3	hSpCas9	negative selection	1120514
63747013	63747036	15	+	26627737	RPE1	viability after 12 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.3710995135051559	[1529]	[311,323]	-3	hSpCas9	negative selection	1202824
63749475	63749498	15	-	26627737	RPE1	viability after 12 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.5982991484588425	[856]	[86,220]	-4	hSpCas9	negative selection	1202825
63756681	63756704	15	-	26627737	RPE1	viability after 12 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.18796904282377502	[1547]	[448,499]	1	hSpCas9	negative selection	1202826
63758277	63758300	15	+	26627737	RPE1	viability after 12 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.39363545417263457	[2253]	[813,775]	2	hSpCas9	negative selection	1202827
63764139	63764162	15	-	26627737	RPE1	viability after 12 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.065714859420266	[454]	[54,61]	-6	hSpCas9	negative selection	1202828
63775052	63775075	15	+	26627737	RPE1	viability after 12 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.2776972579187711	[1359]	[474,408]	1	hSpCas9	negative selection	1202829
63747013	63747036	15	+	26627737	RPE1	viability after 15 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.698045188372132	[1529]	[278,254]	-4	hSpCas9	negative selection	1285139
63749475	63749498	15	-	26627737	RPE1	viability after 15 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.543357820970248	[856]	[174,157]	-3	hSpCas9	negative selection	1285140
63756681	63756704	15	-	26627737	RPE1	viability after 15 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.11663487118820459	[1547]	[515,434]	0	hSpCas9	negative selection	1285141
63758277	63758300	15	+	26627737	RPE1	viability after 15 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	-0.2562060125369392	[2253]	[372,688]	-2	hSpCas9	negative selection	1285142
63764139	63764162	15	-	26627737	RPE1	viability after 15 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.9604181023690028	[454]	[28,36]	-8	hSpCas9	negative selection	1285143
63775052	63775075	15	+	26627737	RPE1	viability after 15 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.22906651791015076	[1359]	[511,391]	1	hSpCas9	negative selection	1285144
63747013	63747036	15	+	26627737	RPE1	viability after 18 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.2857572577027445	[1529]	[198,487]	-2	hSpCas9	negative selection	1367454
63749475	63749498	15	-	26627737	RPE1	viability after 18 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.8013915920964264	[856]	[94,172]	-5	hSpCas9	negative selection	1367455
63756681	63756704	15	-	26627737	RPE1	viability after 18 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.0647522272151222	[1547]	[367,432]	0	hSpCas9	negative selection	1367456
63758277	63758300	15	+	26627737	RPE1	viability after 18 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.15132481766499084	[2253]	[749,595]	1	hSpCas9	negative selection	1367457
63764139	63764162	15	-	26627737	RPE1	viability after 18 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.9876237392913563	[454]	[58,0]	-8	hSpCas9	negative selection	1367458
63775052	63775075	15	+	26627737	RPE1	viability after 18 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.28642603664204924	[1359]	[596,287]	1	hSpCas9	negative selection	1367459
63747013	63747036	15	+	26627737	HeLa	viability after 8 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	1.1424964516879323	[330]	[274,433,240]	8	hSpCas9	negative selection	1449769
63749475	63749498	15	-	26627737	HeLa	viability after 8 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.2472831567686823	[281]	[95,145,68]	-2	hSpCas9	negative selection	1449770
63756681	63756704	15	-	26627737	HeLa	viability after 8 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.005054053795128244	[681]	[354,356,200]	0	hSpCas9	negative selection	1449771
63758277	63758300	15	+	26627737	HeLa	viability after 8 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.075492944110092	[1128]	[766,443,404]	0	hSpCas9	negative selection	1449772
63764139	63764162	15	-	26627737	HeLa	viability after 8 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.30507451599988644	[143]	[83,76,1]	-3	hSpCas9	negative selection	1449773
63775052	63775075	15	+	26627737	HeLa	viability after 8 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.35826297137814195	[514]	[200,254,80]	-3	hSpCas9	negative selection	1449774
63747013	63747036	15	+	26627737	HeLa	viability after 12 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.018916549555353906	[330]	[88,122,203]	0	hSpCas9	negative selection	1532084
63749475	63749498	15	-	26627737	HeLa	viability after 12 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.2515622523470321	[281]	[135,76,83]	-2	hSpCas9	negative selection	1532085
63756681	63756704	15	-	26627737	HeLa	viability after 12 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.05458297445486937	[681]	[229,251,332]	0	hSpCas9	negative selection	1532086
63758277	63758300	15	+	26627737	HeLa	viability after 12 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	-0.13557587863617448	[1128]	[584,309,395]	-1	hSpCas9	negative selection	1532087
63764139	63764162	15	-	26627737	HeLa	viability after 12 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	0.20137471764736836	[143]	[128,30,50]	1	hSpCas9	negative selection	1532088
63775052	63775075	15	+	26627737	HeLa	viability after 12 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.203267464549037	[514]	[52,140,76]	-8	hSpCas9	negative selection	1532089
63747013	63747036	15	+	26627737	HeLa	viability after 15 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.7830288226207058	[330]	[112,341,242]	6	hSpCas9	negative selection	1614399
63749475	63749498	15	-	26627737	HeLa	viability after 15 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.4338127164818136	[281]	[169,236,49]	3	hSpCas9	negative selection	1614400
63756681	63756704	15	-	26627737	HeLa	viability after 15 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.012773084004742863	[681]	[205,394,236]	0	hSpCas9	negative selection	1614401
63758277	63758300	15	+	26627737	HeLa	viability after 15 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.25154563997344126	[1128]	[315,593,749]	2	hSpCas9	negative selection	1614402
63764139	63764162	15	-	26627737	HeLa	viability after 15 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.6789554800535769	[143]	[45,47,13]	-5	hSpCas9	negative selection	1614403
63775052	63775075	15	+	26627737	HeLa	viability after 15 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.06855113323814327	[514]	[108,283,271]	0	hSpCas9	negative selection	1614404
63747013	63747036	15	+	26627737	HeLa	viability after 18 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.8028293928780109	[330]	[82,281,242]	6	hSpCas9	negative selection	1696714
63749475	63749498	15	-	26627737	HeLa	viability after 18 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.4440204381211767	[281]	[113,198,49]	3	hSpCas9	negative selection	1696715
63756681	63756704	15	-	26627737	HeLa	viability after 18 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.055362626074513255	[681]	[148,333,236]	0	hSpCas9	negative selection	1696716
63758277	63758300	15	+	26627737	HeLa	viability after 18 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.22817353225745474	[1128]	[205,477,749]	2	hSpCas9	negative selection	1696717
63764139	63764162	15	-	26627737	HeLa	viability after 18 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.7940337692553336	[143]	[29,33,13]	-6	hSpCas9	negative selection	1696718
63775052	63775075	15	+	26627737	HeLa	viability after 18 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.08244041165868998	[514]	[74,237,271]	0	hSpCas9	negative selection	1696719
63747013	63747036	15	+	26627737	HCT116	viability after 6 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	1.2388935996534862	[522]	[146,219]	6	hSpCas9	negative selection	1779029
63749475	63749498	15	-	26627737	HCT116	viability after 6 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.6383971935374037	[351]	[196,24]	3	hSpCas9	negative selection	1779030
63756681	63756704	15	-	26627737	HCT116	viability after 6 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.1534462855809705	[1259]	[277,122]	-1	hSpCas9	negative selection	1779031
63758277	63758300	15	+	26627737	HCT116	viability after 6 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	-0.23929043390599491	[1633]	[526,46]	-1	hSpCas9	negative selection	1779032
63764139	63764162	15	-	26627737	HCT116	viability after 6 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	1.942165226789927	[242]	[4,224]	8	hSpCas9	negative selection	1779033
63775052	63775075	15	+	26627737	HCT116	viability after 6 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.128591373179068	[724]	[84,33]	-6	hSpCas9	negative selection	1779034
63747013	63747036	15	+	26627737	HCT116	viability after 8 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.27013412043543605	[315]	[189,98,338]	3	hSpCas9	negative selection	1861344
63749475	63749498	15	-	26627737	HCT116	viability after 8 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.4162653702123452	[145]	[113,84,122]	4	hSpCas9	negative selection	1861345
63756681	63756704	15	-	26627737	HCT116	viability after 8 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.08433666387098371	[546]	[257,332,365]	1	hSpCas9	negative selection	1861346
63758277	63758300	15	+	26627737	HCT116	viability after 8 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	-0.0633237860647915	[623]	[434,297,256]	0	hSpCas9	negative selection	1861347
63764139	63764162	15	-	26627737	HCT116	viability after 8 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	3.185412055632228	[7]	[37,19,61]	9	hSpCas9	negative selection	1861348
63775052	63775075	15	+	26627737	HCT116	viability after 8 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.010886122249515379	[324]	[120,134,282]	0	hSpCas9	negative selection	1861349
63747013	63747036	15	+	26627737	HCT116	viability after 9 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.7373927441697046	[522]	[348,140]	5	hSpCas9	negative selection	1943659
63749475	63749498	15	-	26627737	HCT116	viability after 9 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.49898268199677853	[351]	[81,172]	3	hSpCas9	negative selection	1943660
63756681	63756704	15	-	26627737	HCT116	viability after 9 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.4306191148886449	[1259]	[381,144]	-3	hSpCas9	negative selection	1943661
63758277	63758300	15	+	26627737	HCT116	viability after 9 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.036846346600970525	[1633]	[522,387]	0	hSpCas9	negative selection	1943662
63764139	63764162	15	-	26627737	HCT116	viability after 9 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-2.449009709350874	[242]	[12,10]	-9	hSpCas9	negative selection	1943663
63775052	63775075	15	+	26627737	HCT116	viability after 9 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.12652915586942282	[724]	[231,194]	1	hSpCas9	negative selection	1943664
63747013	63747036	15	+	26627737	HCT116	viability after 12 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.049267689450164354	[315]	[135,175,171]	0	hSpCas9	negative selection	2025974
63749475	63749498	15	-	26627737	HCT116	viability after 12 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.5168112435157787	[145]	[70,78,181]	5	hSpCas9	negative selection	2025975
63756681	63756704	15	-	26627737	HCT116	viability after 12 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.07804143660593099	[546]	[234,302,282]	-1	hSpCas9	negative selection	2025976
63758277	63758300	15	+	26627737	HCT116	viability after 12 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.17311738450067327	[623]	[308,470,336]	1	hSpCas9	negative selection	2025977
63764139	63764162	15	-	26627737	HCT116	viability after 12 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	3.6939117377095116	[7]	[92,19,45]	9	hSpCas9	negative selection	2025978
63775052	63775075	15	+	26627737	HCT116	viability after 12 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.2206633887728826	[324]	[111,197,133]	-2	hSpCas9	negative selection	2025979
63747013	63747036	15	+	26627737	HCT116	viability after 15 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.26443935478721614	[315]	[235,189,229]	2	hSpCas9	negative selection	2108289
63749475	63749498	15	-	26627737	HCT116	viability after 15 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.01641406670378709	[145]	[79,56,110]	0	hSpCas9	negative selection	2108290
63756681	63756704	15	-	26627737	HCT116	viability after 15 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.05629834827096858	[546]	[171,370,416]	0	hSpCas9	negative selection	2108291
63758277	63758300	15	+	26627737	HCT116	viability after 15 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.20218511167513475	[623]	[568,366,320]	2	hSpCas9	negative selection	2108292
63764139	63764162	15	-	26627737	HCT116	viability after 15 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	3.099577217239712	[7]	[9,17,85]	9	hSpCas9	negative selection	2108293
63775052	63775075	15	+	26627737	HCT116	viability after 15 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.16275572227099844	[324]	[115,208,168]	-2	hSpCas9	negative selection	2108294
63747013	63747036	15	+	26627737	HCT116	viability after 18 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.07095613897894756	[315]	[99,123,216]	0	hSpCas9	negative selection	2190604
63749475	63749498	15	-	26627737	HCT116	viability after 18 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.40831045294860935	[145]	[105,45,133]	3	hSpCas9	negative selection	2190605
63756681	63756704	15	-	26627737	HCT116	viability after 18 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.12243137620158373	[546]	[146,290,431]	1	hSpCas9	negative selection	2190606
63758277	63758300	15	+	26627737	HCT116	viability after 18 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.08250113456567076	[623]	[383,243,335]	0	hSpCas9	negative selection	2190607
63764139	63764162	15	-	26627737	HCT116	viability after 18 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	2.214909972289129	[7]	[13,26,11]	9	hSpCas9	negative selection	2190608
63775052	63775075	15	+	26627737	HCT116	viability after 18 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.7679758308762977	[324]	[83,93,98]	-6	hSpCas9	negative selection	2190609
63795020	63795043	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTGCCACTGCATTCCAGCCCGG	HERC1	ENSG00000103657	-2.365861438057623	[12,253]	[3,6]	-9	dCas9-VP64	positive selection	2395060
63750805	63750828	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCTGTGGTCCCAGCTACTCGG	HERC1	ENSG00000103657	-1.0019767452838857	[448,49]	[42,8]	-6	dCas9-VP64	positive selection	2399831
63787247	63787270	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATTGCTTGAATCCTGG	HERC1	ENSG00000103657	2.433140723417131	[10,9]	[10,13]	7	dCas9-VP64	positive selection	2414411
63780711	63780734	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GACTCCGTTTCAAAAAAAAAAAG	HERC1	ENSG00000103657	-1.0460794344423097	[101,150]	[12,12]	-6	dCas9-VP64	positive selection	2418713
63747180	63747203	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCGCACCTAG	HERC1	ENSG00000103657	-0.89146844564302	[3,30]	[1,1]	-5	dCas9-VP64	positive selection	2429430
63733910	63733933	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCAGAG	HERC1	ENSG00000103657	-3.2327828351083694	[281,50]	[1,4]	-9	dCas9-VP64	positive selection	2431323
63769334	63769357	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTGAACCTGGGAGGCGGGAG	HERC1	ENSG00000103657	-0.49448069816640183	[10,25]	[2,1]	-2	dCas9-VP64	positive selection	2460655
63741532	63741555	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGGATCACCTGAAGTCGAG	HERC1	ENSG00000103657	-1.080501538256204	[504,81]	[37,20]	-6	dCas9-VP64	positive selection	2472774
63795020	63795043	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTGCCACTGCATTCCAGCCCGG	HERC1	ENSG00000103657	-1.4197804414947919	[336,129]	[25,29]	-9	dCas9-VP64	positive selection	2490315
63750805	63750828	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCTGTGGTCCCAGCTACTCGG	HERC1	ENSG00000103657	0.3516116254360768	[311,292]	[125,125]	3	dCas9-VP64	positive selection	2495086
63787247	63787270	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATTGCTTGAATCCTGG	HERC1	ENSG00000103657	-0.8838793156856553	[97,17]	[18,1]	-8	dCas9-VP64	positive selection	2509666
63780711	63780734	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GACTCCGTTTCAAAAAAAAAAAG	HERC1	ENSG00000103657	0.5138792825400617	[66,44]	[29,21]	4	dCas9-VP64	positive selection	2513968
63747180	63747203	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCGCACCTAG	HERC1	ENSG00000103657	0.12972035773098467	[57,36]	[16,15]	1	dCas9-VP64	positive selection	2524685
63733910	63733933	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCAGAG	HERC1	ENSG00000103657	0.5850522226976638	[88,64]	[38,35]	4	dCas9-VP64	positive selection	2526578
63769334	63769357	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTGAACCTGGGAGGCGGGAG	HERC1	ENSG00000103657	-1.2686416065166946	[152,79]	[23,7]	-9	dCas9-VP64	positive selection	2555910
63741532	63741555	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGGATCACCTGAAGTCGAG	HERC1	ENSG00000103657	0.09148827261213754	[58,380]	[33,114]	0	dCas9-VP64	positive selection	2568029
63758228	63758251	15	+	27260157	DLD1	viability	GTGTACCTTCTACCAACTGATGG	HERC1	ENSG00000103657	-0.0280939666395476	[]	[]	0	hSpCas9	negative selection	2576318
63756681	63756704	15	-	27260157	DLD1	viability	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-1.16830629022531	[]	[]	-7	hSpCas9	negative selection	2581089
63764165	63764188	15	-	27260157	DLD1	viability	CATCTGCTGATCGGAGTCAGTGG	HERC1	ENSG00000103657	0.534037804122968	[]	[]	8	hSpCas9	negative selection	2581454
63775583	63775606	15	+	27260157	DLD1	viability	TCAAGCCATTTCAGCTTCACTGG	HERC1	ENSG00000103657	1.13998240363702	[]	[]	9	hSpCas9	negative selection	2582630
63749754	63749777	15	-	27260157	DLD1	viability	TGTGGAGCTTGTCTAGGTTGTGG	HERC1	ENSG00000103657	-0.71293667491601	[]	[]	-5	hSpCas9	negative selection	2583167
63758277	63758300	15	+	27260157	DLD1	viability	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	-0.0202573373197172	[]	[]	0	hSpCas9	negative selection	2583566
63758176	63758199	15	+	27260157	DLD1	viability	GTCTGTGCATCAGAGAAACTAGG	HERC1	ENSG00000103657	0.964097731746554	[]	[]	9	hSpCas9	negative selection	2607573
63775052	63775075	15	+	27260157	DLD1	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.751134915496402	[]	[]	-5	hSpCas9	negative selection	2609155
63764139	63764162	15	-	27260157	DLD1	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	1.18347032666645	[]	[]	9	hSpCas9	negative selection	2614591
63775386	63775409	15	-	27260157	DLD1	viability	TGATGAGCAGGACCACTATTTGG	HERC1	ENSG00000103657	0.0834874117069562	[]	[]	3	hSpCas9	negative selection	2618706
63756441	63756464	15	-	27260157	DLD1	viability	CTTATTCAGGGACCTCTACAAGG	HERC1	ENSG00000103657	0.845051627956225	[]	[]	9	hSpCas9	negative selection	2620641
63758276	63758299	15	-	27260157	DLD1	viability	CATTGTCTCCGAAACCTGTGAGG	HERC1	ENSG00000103657	-0.241054099578057	[]	[]	-2	hSpCas9	negative selection	2621220
63775152	63775175	15	+	27260157	DLD1	viability	TAAGTGCATCAGTGCTTGACCGG	HERC1	ENSG00000103657	-0.0670757536934999	[]	[]	0	hSpCas9	negative selection	2621813
63756671	63756694	15	-	27260157	DLD1	viability	CTTGCGGGAAAGGCAGCTATGGG	HERC1	ENSG00000103657	-0.186744349161897	[]	[]	-1	hSpCas9	negative selection	2623801
63775564	63775587	15	-	27260157	DLD1	viability	TTGAACACTTGAACAGCTCCTGG	HERC1	ENSG00000103657	0.793112412732933	[]	[]	9	hSpCas9	negative selection	2640932
63749409	63749432	15	-	27260157	DLD1	viability	GCTATTCAGCAGATTTCGGCTGG	HERC1	ENSG00000103657	-0.148822016691418	[]	[]	-1	hSpCas9	negative selection	2641702
63747010	63747033	15	-	27260157	DLD1	viability	TGCTCTTGCACTTGCGGGAGGGG	HERC1	ENSG00000103657	-0.865392948905806	[]	[]	-6	hSpCas9	negative selection	2643733
63764132	63764155	15	+	27260157	DLD1	viability	GCACAAGCCATCCGATGTTCTGG	HERC1	ENSG00000103657	0.616449763408196	[]	[]	8	hSpCas9	negative selection	2643775
63774956	63774979	15	+	27260157	DLD1	viability	GATAAGCAGTCCAAGCCCATAGG	HERC1	ENSG00000103657	-0.34584694712736	[]	[]	-3	hSpCas9	negative selection	2644442
63774848	63774871	15	-	27260157	DLD1	viability	CTTGGTTTGGCAGCTCAACGAGG	HERC1	ENSG00000103657	0.321084547529259	[]	[]	4	hSpCas9	negative selection	2646631
63758228	63758251	15	+	27260157	HT1080	viability	GTGTACCTTCTACCAACTGATGG	HERC1	ENSG00000103657	0.0608783116698665	[]	[]	0	hSpCas9	negative selection	2652448
63756681	63756704	15	-	27260157	HT1080	viability	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.195730390166284	[]	[]	0	hSpCas9	negative selection	2657219
63764165	63764188	15	-	27260157	HT1080	viability	CATCTGCTGATCGGAGTCAGTGG	HERC1	ENSG00000103657	0.576293387251773	[]	[]	5	hSpCas9	negative selection	2657584
63775583	63775606	15	+	27260157	HT1080	viability	TCAAGCCATTTCAGCTTCACTGG	HERC1	ENSG00000103657	0.926934565798615	[]	[]	7	hSpCas9	negative selection	2658760
63749754	63749777	15	-	27260157	HT1080	viability	TGTGGAGCTTGTCTAGGTTGTGG	HERC1	ENSG00000103657	-0.16870364299284	[]	[]	0	hSpCas9	negative selection	2659297
63758277	63758300	15	+	27260157	HT1080	viability	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.332844592007096	[]	[]	3	hSpCas9	negative selection	2659696
63758176	63758199	15	+	27260157	HT1080	viability	GTCTGTGCATCAGAGAAACTAGG	HERC1	ENSG00000103657	0.413752615653158	[]	[]	4	hSpCas9	negative selection	2683703
63775052	63775075	15	+	27260157	HT1080	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.109191956253155	[]	[]	1	hSpCas9	negative selection	2685285
63764139	63764162	15	-	27260157	HT1080	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	1.15661302174211	[]	[]	8	hSpCas9	negative selection	2690721
63775386	63775409	15	-	27260157	HT1080	viability	TGATGAGCAGGACCACTATTTGG	HERC1	ENSG00000103657	-0.107234223332506	[]	[]	0	hSpCas9	negative selection	2694836
63756441	63756464	15	-	27260157	HT1080	viability	CTTATTCAGGGACCTCTACAAGG	HERC1	ENSG00000103657	-0.172766093210271	[]	[]	0	hSpCas9	negative selection	2696771
63758276	63758299	15	-	27260157	HT1080	viability	CATTGTCTCCGAAACCTGTGAGG	HERC1	ENSG00000103657	0.0775997787748847	[]	[]	0	hSpCas9	negative selection	2697350
63775152	63775175	15	+	27260157	HT1080	viability	TAAGTGCATCAGTGCTTGACCGG	HERC1	ENSG00000103657	-0.953221112369045	[]	[]	-8	hSpCas9	negative selection	2697943
63756671	63756694	15	-	27260157	HT1080	viability	CTTGCGGGAAAGGCAGCTATGGG	HERC1	ENSG00000103657	-0.611174987629825	[]	[]	-8	hSpCas9	negative selection	2699931
63775564	63775587	15	-	27260157	HT1080	viability	TTGAACACTTGAACAGCTCCTGG	HERC1	ENSG00000103657	0.132794566657044	[]	[]	1	hSpCas9	negative selection	2717062
63749409	63749432	15	-	27260157	HT1080	viability	GCTATTCAGCAGATTTCGGCTGG	HERC1	ENSG00000103657	-0.448437282968092	[]	[]	-7	hSpCas9	negative selection	2717832
63747010	63747033	15	-	27260157	HT1080	viability	TGCTCTTGCACTTGCGGGAGGGG	HERC1	ENSG00000103657	-0.24270828811134	[]	[]	0	hSpCas9	negative selection	2719863
63764132	63764155	15	+	27260157	HT1080	viability	GCACAAGCCATCCGATGTTCTGG	HERC1	ENSG00000103657	0.299186438041417	[]	[]	3	hSpCas9	negative selection	2719905
63774956	63774979	15	+	27260157	HT1080	viability	GATAAGCAGTCCAAGCCCATAGG	HERC1	ENSG00000103657	-0.360664549278512	[]	[]	-7	hSpCas9	negative selection	2720572
63774848	63774871	15	-	27260157	HT1080	viability	CTTGGTTTGGCAGCTCAACGAGG	HERC1	ENSG00000103657	-0.0897248855318483	[]	[]	0	hSpCas9	negative selection	2722761
63758228	63758251	15	+	27260157	MKN45	viability	GTGTACCTTCTACCAACTGATGG	HERC1	ENSG00000103657	-1.04998349430425	[]	[]	-8	hSpCas9	negative selection	2728578
63756681	63756704	15	-	27260157	MKN45	viability	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-1.19117809316527	[]	[]	-8	hSpCas9	negative selection	2733349
63764165	63764188	15	-	27260157	MKN45	viability	CATCTGCTGATCGGAGTCAGTGG	HERC1	ENSG00000103657	-0.123749048378146	[]	[]	0	hSpCas9	negative selection	2733714
63775583	63775606	15	+	27260157	MKN45	viability	TCAAGCCATTTCAGCTTCACTGG	HERC1	ENSG00000103657	1.25315118976725	[]	[]	9	hSpCas9	negative selection	2734890
63749754	63749777	15	-	27260157	MKN45	viability	TGTGGAGCTTGTCTAGGTTGTGG	HERC1	ENSG00000103657	-1.71338816514428	[]	[]	-9	hSpCas9	negative selection	2735427
63758277	63758300	15	+	27260157	MKN45	viability	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	1.02390866041822	[]	[]	8	hSpCas9	negative selection	2735826
63758176	63758199	15	+	27260157	MKN45	viability	GTCTGTGCATCAGAGAAACTAGG	HERC1	ENSG00000103657	0.108887784295814	[]	[]	4	hSpCas9	negative selection	2759833
63775052	63775075	15	+	27260157	MKN45	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-2.06095660935832	[]	[]	-9	hSpCas9	negative selection	2761415
63764139	63764162	15	-	27260157	MKN45	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	0.808450805233502	[]	[]	8	hSpCas9	negative selection	2766851
63775386	63775409	15	-	27260157	MKN45	viability	TGATGAGCAGGACCACTATTTGG	HERC1	ENSG00000103657	-0.241518465144877	[]	[]	-1	hSpCas9	negative selection	2770966
63756441	63756464	15	-	27260157	MKN45	viability	CTTATTCAGGGACCTCTACAAGG	HERC1	ENSG00000103657	-0.476154422392467	[]	[]	-6	hSpCas9	negative selection	2772901
63758276	63758299	15	-	27260157	MKN45	viability	CATTGTCTCCGAAACCTGTGAGG	HERC1	ENSG00000103657	-0.424663570408675	[]	[]	-6	hSpCas9	negative selection	2773480
63775152	63775175	15	+	27260157	MKN45	viability	TAAGTGCATCAGTGCTTGACCGG	HERC1	ENSG00000103657	-1.42372005411023	[]	[]	-8	hSpCas9	negative selection	2774073
63756671	63756694	15	-	27260157	MKN45	viability	CTTGCGGGAAAGGCAGCTATGGG	HERC1	ENSG00000103657	-0.827532816753531	[]	[]	-7	hSpCas9	negative selection	2776061
63775564	63775587	15	-	27260157	MKN45	viability	TTGAACACTTGAACAGCTCCTGG	HERC1	ENSG00000103657	0.682416193226761	[]	[]	7	hSpCas9	negative selection	2793192
63749409	63749432	15	-	27260157	MKN45	viability	GCTATTCAGCAGATTTCGGCTGG	HERC1	ENSG00000103657	0.684598885193649	[]	[]	7	hSpCas9	negative selection	2793962
63747010	63747033	15	-	27260157	MKN45	viability	TGCTCTTGCACTTGCGGGAGGGG	HERC1	ENSG00000103657	-0.674854185933273	[]	[]	-7	hSpCas9	negative selection	2795993
63764132	63764155	15	+	27260157	MKN45	viability	GCACAAGCCATCCGATGTTCTGG	HERC1	ENSG00000103657	1.02839971051064	[]	[]	8	hSpCas9	negative selection	2796035
63774956	63774979	15	+	27260157	MKN45	viability	GATAAGCAGTCCAAGCCCATAGG	HERC1	ENSG00000103657	0.355923283188176	[]	[]	6	hSpCas9	negative selection	2796702
63774848	63774871	15	-	27260157	MKN45	viability	CTTGGTTTGGCAGCTCAACGAGG	HERC1	ENSG00000103657	-0.011525534615167	[]	[]	0	hSpCas9	negative selection	2798891
63758228	63758251	15	+	27260157	RKO	viability	GTGTACCTTCTACCAACTGATGG	HERC1	ENSG00000103657	-0.66092985809156	[]	[]	-7	hSpCas9	negative selection	2804708
63756681	63756704	15	-	27260157	RKO	viability	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.699373218983443	[]	[]	-7	hSpCas9	negative selection	2809479
63764165	63764188	15	-	27260157	RKO	viability	CATCTGCTGATCGGAGTCAGTGG	HERC1	ENSG00000103657	0.800351053206933	[]	[]	8	hSpCas9	negative selection	2809844
63775583	63775606	15	+	27260157	RKO	viability	TCAAGCCATTTCAGCTTCACTGG	HERC1	ENSG00000103657	0.806164011908265	[]	[]	8	hSpCas9	negative selection	2811020
63749754	63749777	15	-	27260157	RKO	viability	TGTGGAGCTTGTCTAGGTTGTGG	HERC1	ENSG00000103657	-0.554630293748682	[]	[]	-7	hSpCas9	negative selection	2811557
63758277	63758300	15	+	27260157	RKO	viability	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.0457757015916709	[]	[]	0	hSpCas9	negative selection	2811956
63758176	63758199	15	+	27260157	RKO	viability	GTCTGTGCATCAGAGAAACTAGG	HERC1	ENSG00000103657	0.601560525449492	[]	[]	3	hSpCas9	negative selection	2835963
63775052	63775075	15	+	27260157	RKO	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.189632683335477	[]	[]	1	hSpCas9	negative selection	2837545
63764139	63764162	15	-	27260157	RKO	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	0.903366057277062	[]	[]	8	hSpCas9	negative selection	2842981
63775386	63775409	15	-	27260157	RKO	viability	TGATGAGCAGGACCACTATTTGG	HERC1	ENSG00000103657	0.00239732538699751	[]	[]	0	hSpCas9	negative selection	2847096
63756441	63756464	15	-	27260157	RKO	viability	CTTATTCAGGGACCTCTACAAGG	HERC1	ENSG00000103657	0.39784808008954	[]	[]	2	hSpCas9	negative selection	2849031
63758276	63758299	15	-	27260157	RKO	viability	CATTGTCTCCGAAACCTGTGAGG	HERC1	ENSG00000103657	0.165925490636514	[]	[]	0	hSpCas9	negative selection	2849610
63775152	63775175	15	+	27260157	RKO	viability	TAAGTGCATCAGTGCTTGACCGG	HERC1	ENSG00000103657	-0.603478759438314	[]	[]	-7	hSpCas9	negative selection	2850203
63756671	63756694	15	-	27260157	RKO	viability	CTTGCGGGAAAGGCAGCTATGGG	HERC1	ENSG00000103657	-0.800263857244385	[]	[]	-7	hSpCas9	negative selection	2852191
63775564	63775587	15	-	27260157	RKO	viability	TTGAACACTTGAACAGCTCCTGG	HERC1	ENSG00000103657	0.271331214101477	[]	[]	1	hSpCas9	negative selection	2869322
63749409	63749432	15	-	27260157	RKO	viability	GCTATTCAGCAGATTTCGGCTGG	HERC1	ENSG00000103657	-1.06878090528876	[]	[]	-8	hSpCas9	negative selection	2870092
63747010	63747033	15	-	27260157	RKO	viability	TGCTCTTGCACTTGCGGGAGGGG	HERC1	ENSG00000103657	-0.501956831305492	[]	[]	-6	hSpCas9	negative selection	2872123
63764132	63764155	15	+	27260157	RKO	viability	GCACAAGCCATCCGATGTTCTGG	HERC1	ENSG00000103657	0.880395164191356	[]	[]	8	hSpCas9	negative selection	2872165
63774956	63774979	15	+	27260157	RKO	viability	GATAAGCAGTCCAAGCCCATAGG	HERC1	ENSG00000103657	0.520372446138618	[]	[]	2	hSpCas9	negative selection	2872832
63774848	63774871	15	-	27260157	RKO	viability	CTTGGTTTGGCAGCTCAACGAGG	HERC1	ENSG00000103657	0.30916258701087	[]	[]	1	hSpCas9	negative selection	2875021
63758228	63758251	15	+	27260157	SF268	viability	GTGTACCTTCTACCAACTGATGG	HERC1	ENSG00000103657	0.0454356597643488	[]	[]	0	hSpCas9	negative selection	2880838
63756681	63756704	15	-	27260157	SF268	viability	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.407806498680012	[]	[]	-3	hSpCas9	negative selection	2885609
63764165	63764188	15	-	27260157	SF268	viability	CATCTGCTGATCGGAGTCAGTGG	HERC1	ENSG00000103657	0.718705546911792	[]	[]	8	hSpCas9	negative selection	2885974
63775583	63775606	15	+	27260157	SF268	viability	TCAAGCCATTTCAGCTTCACTGG	HERC1	ENSG00000103657	1.60682666938091	[]	[]	9	hSpCas9	negative selection	2887150
63749754	63749777	15	-	27260157	SF268	viability	TGTGGAGCTTGTCTAGGTTGTGG	HERC1	ENSG00000103657	-0.373444382764904	[]	[]	-3	hSpCas9	negative selection	2887687
63758277	63758300	15	+	27260157	SF268	viability	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.695216140979183	[]	[]	8	hSpCas9	negative selection	2888086
63758176	63758199	15	+	27260157	SF268	viability	GTCTGTGCATCAGAGAAACTAGG	HERC1	ENSG00000103657	-1.18791971549603	[]	[]	-7	hSpCas9	negative selection	2912093
63775052	63775075	15	+	27260157	SF268	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.736416003618606	[]	[]	-5	hSpCas9	negative selection	2913675
63764139	63764162	15	-	27260157	SF268	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	1.05733138666122	[]	[]	9	hSpCas9	negative selection	2919111
63775386	63775409	15	-	27260157	SF268	viability	TGATGAGCAGGACCACTATTTGG	HERC1	ENSG00000103657	0.0369959310215447	[]	[]	0	hSpCas9	negative selection	2923226
63756441	63756464	15	-	27260157	SF268	viability	CTTATTCAGGGACCTCTACAAGG	HERC1	ENSG00000103657	0.711349053712525	[]	[]	8	hSpCas9	negative selection	2925161
63758276	63758299	15	-	27260157	SF268	viability	CATTGTCTCCGAAACCTGTGAGG	HERC1	ENSG00000103657	0.19257970975031	[]	[]	0	hSpCas9	negative selection	2925740
63775152	63775175	15	+	27260157	SF268	viability	TAAGTGCATCAGTGCTTGACCGG	HERC1	ENSG00000103657	-0.58855571812553	[]	[]	-4	hSpCas9	negative selection	2926333
63756671	63756694	15	-	27260157	SF268	viability	CTTGCGGGAAAGGCAGCTATGGG	HERC1	ENSG00000103657	-0.800466721639524	[]	[]	-6	hSpCas9	negative selection	2928321
63775564	63775587	15	-	27260157	SF268	viability	TTGAACACTTGAACAGCTCCTGG	HERC1	ENSG00000103657	0.8624030016969	[]	[]	9	hSpCas9	negative selection	2945452
63749409	63749432	15	-	27260157	SF268	viability	GCTATTCAGCAGATTTCGGCTGG	HERC1	ENSG00000103657	0.86699029367479	[]	[]	9	hSpCas9	negative selection	2946222
63747010	63747033	15	-	27260157	SF268	viability	TGCTCTTGCACTTGCGGGAGGGG	HERC1	ENSG00000103657	-1.22350476955846	[]	[]	-7	hSpCas9	negative selection	2948253
63764132	63764155	15	+	27260157	SF268	viability	GCACAAGCCATCCGATGTTCTGG	HERC1	ENSG00000103657	0.921745946161218	[]	[]	9	hSpCas9	negative selection	2948295
63774956	63774979	15	+	27260157	SF268	viability	GATAAGCAGTCCAAGCCCATAGG	HERC1	ENSG00000103657	0.481788817559765	[]	[]	7	hSpCas9	negative selection	2948962
63774848	63774871	15	-	27260157	SF268	viability	CTTGGTTTGGCAGCTCAACGAGG	HERC1	ENSG00000103657	0.336821175310723	[]	[]	4	hSpCas9	negative selection	2951151
63725313	63725336	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTACACCGTCACTGAACAGTGG	HERC1	ENSG00000103657	0.13222525152901565	[4,4]	[5,3]	2	hSpCas9	positive selection	2993056
63746917	63746940	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCCCAGATGAAATCCAAGAGG	HERC1	ENSG00000103657	0.12864298413938877	[3,3]	[3,3]	2	hSpCas9	positive selection	2993057
63725313	63725336	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTACACCGTCACTGAACAGTGG	HERC1	ENSG00000103657	-0.3303626010486108	[4,4]	[4,0]	-5	hSpCas9	positive selection	3060914
63746917	63746940	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCCCAGATGAAATCCAAGAGG	HERC1	ENSG00000103657	-0.2729331093566978	[3,3]	[2,1]	-4	hSpCas9	positive selection	3060915
63775171	63775194		-	24336571	A375	resistance to PLX after 7 days	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.2594033511020851	[13,14]	[12,10]	-7	hSpCas9	positive selection	3118803
63716418	63716441		+	24336571	A375	resistance to PLX after 7 days	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.02671115978402816	[12,13]	[15,11]	1	hSpCas9	positive selection	3118804
63775093	63775116		-	24336571	A375	resistance to PLX after 7 days	TTGCGCTTCTAAGACAAAGTTGG	HERC1	ENSG00000103657	-0.009724360620200878	[4,5]	[5,3]	0	hSpCas9	positive selection	3118805
63775171	63775194		-	24336571	A375	resistance to PLX after 14 days	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	1.6063719274731696	[8,8]	[14,10]	9	hSpCas9	positive selection	3176596
63716418	63716441		+	24336571	A375	resistance to PLX after 14 days	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.7134967349713005	[13,8]	[7,8]	6	hSpCas9	positive selection	3176597
63775093	63775116		-	24336571	A375	resistance to PLX after 14 days	TTGCGCTTCTAAGACAAAGTTGG	HERC1	ENSG00000103657	1.2043027143855884	[3,2]	[3,3]	8	hSpCas9	positive selection	3176598
63775171	63775194		-	24336571	A375	viability after 7 days	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.3052990174293751	[11]	[13,14]	4	hSpCas9	negative selection	3234389
63716418	63716441		+	24336571	A375	viability after 7 days	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.2989834518516667	[11]	[12,13]	4	hSpCas9	negative selection	3234390
63775093	63775116		-	24336571	A375	viability after 7 days	TTGCGCTTCTAAGACAAAGTTGG	HERC1	ENSG00000103657	-0.35179726513662146	[6]	[4,5]	-5	hSpCas9	negative selection	3234391
63775171	63775194		-	24336571	A375	viability after 14 days	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.32275411281969646	[11]	[8,8]	-4	hSpCas9	negative selection	3292182
63716418	63716441		+	24336571	A375	viability after 14 days	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.08486580209800934	[11]	[13,8]	1	hSpCas9	negative selection	3292183
63775093	63775116		-	24336571	A375	viability after 14 days	TTGCGCTTCTAAGACAAAGTTGG	HERC1	ENSG00000103657	-0.686944808668577	[6]	[3,2]	-7	hSpCas9	negative selection	3292184
63775171	63775194	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	1.32844502729549	[48,72]	[0,0]	6	hSpCas9	positive selection	3353248
63716418	63716441	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	1.6140358953951288	[46,52]	[0,0]	6	hSpCas9	positive selection	3353249
63775052	63775075	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.19652271365529742	[147,202]	[0,0]	-1	hSpCas9	positive selection	3353250
63716304	63716327	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.6734111261170512	[243,243]	[0,0]	-4	hSpCas9	positive selection	3372444
63725312	63725335	15	+	26780180	HT29	viability (Avana library 4 designs)	TCTACACCGTCACTGAACAGTGG	HERC1	ENSG00000103657	-0.0231374286730007	[]	[]	0	hSpCas9	negative selection	3430317
63746917	63746940	15	-	26780180	HT29	viability (Avana library 4 designs)	TGTCCCAGATGAAATCCAAGAGG	HERC1	ENSG00000103657	0.690236428407094	[]	[]	2	hSpCas9	negative selection	3430318
63746917	63746940	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCCAGATGAAATCCAAGAGG	HERC1	ENSG00000103657	-4.03298463684794	[]	[]	-4	hSpCas9	negative selection	3515418
63725312	63725335	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTACACCGTCACTGAACAGTGG	HERC1	ENSG00000103657	-3.06849102240247	[]	[]	-4	hSpCas9	negative selection	3515419
63775320	63775343	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCAGATTCCCCATTTGCCGGGG	HERC1	ENSG00000103657	0.0646231747362645	[]	[]	0	hSpCas9	negative selection	3515420
63746917	63746940	15	-	26780180	A375	viability (Avana lentiGuide)	TGTCCCAGATGAAATCCAAGAGG	HERC1	ENSG00000103657	-1.26325334585307	[]	[]	-2	hSpCas9	negative selection	3624077
63725312	63725335	15	+	26780180	A375	viability (Avana lentiGuide)	TCTACACCGTCACTGAACAGTGG	HERC1	ENSG00000103657	-0.62067198368714	[]	[]	-1	hSpCas9	negative selection	3624078
63775320	63775343	15	-	26780180	A375	viability (Avana lentiGuide)	TTCAGATTCCCCATTTGCCGGGG	HERC1	ENSG00000103657	1.88179609134256	[]	[]	2	hSpCas9	negative selection	3624079
63746917	63746940	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCCAGATGAAATCCAAGAGG	HERC1	ENSG00000103657	-0.8141014733147951	[5]	[1,2]	-8	hSpCas9	positive selection	3732736
63725312	63725335	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTACACCGTCACTGAACAGTGG	HERC1	ENSG00000103657	-0.2359952764228948	[5]	[4,4]	-4	hSpCas9	positive selection	3732737
63775320	63775343	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCAGATTCCCCATTTGCCGGGG	HERC1	ENSG00000103657	-0.1211474887464754	[6]	[5,5]	-2	hSpCas9	positive selection	3732738
63746917	63746940	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCCAGATGAAATCCAAGAGG	HERC1	ENSG00000103657	0.31974497991789214	[4]	[5,4]	8	hSpCas9	positive selection	3841343
63725312	63725335	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTACACCGTCACTGAACAGTGG	HERC1	ENSG00000103657	-0.22780681598036417	[6]	[6,3]	-3	hSpCas9	positive selection	3841344
63775320	63775343	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCAGATTCCCCATTTGCCGGGG	HERC1	ENSG00000103657	0.1738464462237151	[7]	[7,7]	4	hSpCas9	positive selection	3841345
63775171	63775194	15	-	26780180	A375	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	1.10717854564401	[]	[]	5	hSpCas9	negative selection	3947414
63716418	63716441	15	+	26780180	A375	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	1.16995357741879	[]	[]	6	hSpCas9	negative selection	3947415
63716304	63716327	15	-	26780180	A375	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	1.834217745158	[]	[]	9	hSpCas9	negative selection	3947416
63775052	63775075	15	+	26780180	A375	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	1.14261432338791	[]	[]	6	hSpCas9	negative selection	3947417
63775171	63775194	15	-	26780180	HT29	viability (GeCKOv2 library)	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	1.31620597728889	[]	[]	6	hSpCas9	negative selection	4055380
63716418	63716441	15	+	26780180	HT29	viability (GeCKOv2 library)	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	1.34428577987973	[]	[]	6	hSpCas9	negative selection	4055381
63716304	63716327	15	-	26780180	HT29	viability (GeCKOv2 library)	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	1.64966129202044	[]	[]	8	hSpCas9	negative selection	4055382
63775052	63775075	15	+	26780180	HT29	viability (GeCKOv2 library)	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.92914317955032	[]	[]	4	hSpCas9	negative selection	4055383
63775171	63775194	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.212700724120986	[3]	[1,3]	5	hSpCas9	positive selection	4142263
63716418	63716441	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.030534640355902608	[3]	[1,3]	0	hSpCas9	positive selection	4142265
63775093	63775116	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGCGCTTCTAAGACAAAGTTGG	HERC1	ENSG00000103657	0.12373062618572667	[2]	[1,1]	3	hSpCas9	positive selection	4142266
63775171	63775194	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	1.4064363468151402	[3]	[4,2,1,4]	9	hSpCas9	positive selection	4206285
63716418	63716441	15	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.1217129645477446	[3]	[3,0,0,0]	-2	hSpCas9	positive selection	4206287
63775093	63775116	15	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGCGCTTCTAAGACAAAGTTGG	HERC1	ENSG00000103657	1.2071534167578428	[0]	[0,2,0,0]	8	hSpCas9	positive selection	4206288
63775171	63775194	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.279247392233567	[1]	[1,0]	-5	hSpCas9	positive selection	4274832
63716418	63716441	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.6069266369187749	[1]	[0,0]	-8	hSpCas9	positive selection	4274833
63775052	63775075	15	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.24170815100909582	[3]	[2,1]	-5	hSpCas9	positive selection	4274834
63716304	63716327	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.10625118330999556	[3]	[4,1]	-2	hSpCas9	positive selection	4339093
63675038	63675060	15	+	27760321	OCIAML3	viability	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	-0.13696296742683994	[369,310]	[209,281]	-1	hSpCas9	negative selection	4406637
63734786	63734808	15	+	27760321	OCIAML3	viability	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	-0.0715062460650237	[646,482]	[369,477]	-1	hSpCas9	negative selection	4406638
63775130	63775152	15	-	27760321	OCIAML3	viability	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.33940744126645006	[247,220]	[119,176]	-4	hSpCas9	negative selection	4406639
63675038	63675060	15	+	27760321	OCIAML2	viability	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	0.7567992351109318	[369,310]	[429,507]	8	hSpCas9	negative selection	4490100
63734786	63734808	15	+	27760321	OCIAML2	viability	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	0.15828629016338497	[646,482]	[512,495]	2	hSpCas9	negative selection	4490101
63775130	63775152	15	-	27760321	OCIAML2	viability	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.01637450989165834	[247,220]	[144,242]	0	hSpCas9	negative selection	4490102
63675038	63675060	15	+	27760321	MV411	viability	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	0.7756629753491271	[369,310]	[385,378]	6	hSpCas9	negative selection	4573563
63734786	63734808	15	+	27760321	MV411	viability	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	-0.6685548873351683	[646,482]	[166,330]	-4	hSpCas9	negative selection	4573564
63775130	63775152	15	-	27760321	MV411	viability	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.19914599826358814	[247,220]	[134,133]	-1	hSpCas9	negative selection	4573565
63675038	63675060	15	+	27760321	HL60	viability	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	0.17555985625487674	[369,310]	[343,279]	2	hSpCas9	negative selection	4657026
63734786	63734808	15	+	27760321	HL60	viability	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	-0.3399681251757951	[646,482]	[294,431]	-4	hSpCas9	negative selection	4657027
63775130	63775152	15	-	27760321	HL60	viability	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-1.2803654596512735	[247,220]	[86,69]	-8	hSpCas9	negative selection	4657028
63675038	63675060	15	+	27760321	HT1080	viability	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	1.9852788731802917	[310,242]	[361,518]	9	hSpCas9	negative selection	4740489
63734786	63734808	15	+	27760321	HT1080	viability	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	0.9730546938832743	[482,376]	[404,260]	5	hSpCas9	negative selection	4740490
63775130	63775152	15	-	27760321	HT1080	viability	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	0.8587451444144253	[220,172]	[117,168]	4	hSpCas9	negative selection	4740491
63675038	63675060	15	+	27760321	HT29	viability after 7 days	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	0.9716462402291739	[310,242]	[751,427,914]	9	hSpCas9	negative selection	4823952
63734786	63734808	15	+	27760321	HT29	viability after 7 days	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	0.20926361568675556	[482,376]	[739,553,636]	3	hSpCas9	negative selection	4823953
63775130	63775152	15	-	27760321	HT29	viability after 7 days	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.291855914190134	[220,172]	[294,160,177]	-4	hSpCas9	negative selection	4823954
63675038	63675060	15	+	27760321	HT29	viability after 25 days	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	1.1793042502620357	[310,242]	[459,738,995]	9	hSpCas9	negative selection	4907415
63734786	63734808	15	+	27760321	HT29	viability after 25 days	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	1.1078388966140076	[482,376]	[1154,840,1186]	9	hSpCas9	negative selection	4907416
63775130	63775152	15	-	27760321	HT29	viability after 25 days	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.06585822955090825	[220,172]	[228,149,270]	0	hSpCas9	negative selection	4907417
63675038	63675060	15	+	27760321	HT29	viability after 22 days	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	1.0690332502383462	[310,242]	[695,645,672]	9	hSpCas9	negative selection	4990878
63734786	63734808	15	+	27760321	HT29	viability after 22 days	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	1.108943629658037	[482,376]	[1221,1177,809]	9	hSpCas9	negative selection	4990879
63775130	63775152	15	-	27760321	HT29	viability after 22 days	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.04952874120017703	[220,172]	[257,207,192]	0	hSpCas9	negative selection	4990880
63675038	63675060	15	+	27760321	HT29	viability after 19 days	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	0.6422665042693743	[310,242]	[527,339,613]	6	hSpCas9	negative selection	5074341
63734786	63734808	15	+	27760321	HT29	viability after 19 days	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	0.639502331296832	[482,376]	[842,915,554]	6	hSpCas9	negative selection	5074342
63775130	63775152	15	-	27760321	HT29	viability after 19 days	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.913359571291271	[220,172]	[173,82,107]	-6	hSpCas9	negative selection	5074343
63675038	63675060	15	+	27760321	HT29	viability after 16 days	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	1.1031553578249675	[310,242]	[578,669,739]	9	hSpCas9	negative selection	5157804
63734786	63734808	15	+	27760321	HT29	viability after 16 days	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	0.5693543804725087	[482,376]	[915,697,546]	6	hSpCas9	negative selection	5157805
63775130	63775152	15	-	27760321	HT29	viability after 16 days	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.1691552062229016	[220,172]	[212,185,190]	-2	hSpCas9	negative selection	5157806
63675038	63675060	15	+	27760321	HT29	viability after 13 days	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	0.6184416360164007	[310,242]	[412,535,528]	7	hSpCas9	negative selection	5241267
63734786	63734808	15	+	27760321	HT29	viability after 13 days	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	0.41059460553635013	[482,376]	[535,782,669]	5	hSpCas9	negative selection	5241268
63775130	63775152	15	-	27760321	HT29	viability after 13 days	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.17967031914472886	[220,172]	[184,244,176]	-2	hSpCas9	negative selection	5241269
63675038	63675060	15	+	27760321	HT29	viability after 10 days	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	1.0070617278051766	[310,242]	[631,656,792]	9	hSpCas9	negative selection	5324730
63734786	63734808	15	+	27760321	HT29	viability after 10 days	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	0.2598199240793521	[482,376]	[680,437,799]	3	hSpCas9	negative selection	5324731
63775130	63775152	15	-	27760321	HT29	viability after 10 days	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.8126261328139046	[220,172]	[156,108,152]	-7	hSpCas9	negative selection	5324732
63675038	63675060	15	+	27760321	MOLM13	viability	GCGCCACATCAAACGGCAATGG	HERC1	ENSG00000103657	1.1709047308825622	[369,310]	[492,377]	8	hSpCas9	negative selection	5408193
63734786	63734808	15	+	27760321	MOLM13	viability	CCATCCGTTCTCGTAATGGAGG	HERC1	ENSG00000103657	1.102384031072227	[646,482]	[805,569]	7	hSpCas9	negative selection	5408194
63775130	63775152	15	-	27760321	MOLM13	viability	TAGAAATGGGTGTTCGAACTGG	HERC1	ENSG00000103657	-0.251341974231714	[247,220]	[211,24]	-2	hSpCas9	negative selection	5408195
63833504	63833527	15	+	27661255	K562	viability	GACGTTGTAAGCCGCTGGAGGGG	HERC1	ENSG00000103657	-0.03083114508417545	[521,696]	[519,434]	-1	dCas9-KRAB	negative selection	5484448
63833934	63833957	15	+	27661255	K562	viability	GTCAAAGGGAAAGACGTAAGAGG	HERC1	ENSG00000103657	-0.023995890937037356	[473,457]	[388,346]	-1	dCas9-KRAB	negative selection	5484449
63833940	63833963	15	+	27661255	K562	viability	GGGAAAGACGTAAGAGGCGGCGG	HERC1	ENSG00000103657	-0.10146844974356828	[432,311]	[319,243]	-4	dCas9-KRAB	negative selection	5484450
63833699	63833722	15	-	27661255	K562	viability	GGGCCGGCCGGGGCCGTTTCGGG	HERC1	ENSG00000103657	-1.1183872296993052	[686,621]	[237,243]	-8	dCas9-KRAB	negative selection	5484451
63775171	63775194	15	-	27260156	BXPC3	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.3695621885439473	[144]	[196,166,159,267]	7	hSpCas9	negative selection	5547292
63716418	63716441	15	+	27260156	BXPC3	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.31058205479271694	[194]	[133,187,142,196]	-6	hSpCas9	negative selection	5547293
63775052	63775075	15	+	27260156	BXPC3	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.06793567020545638	[609]	[594,685,657,746]	1	hSpCas9	negative selection	5547294
63716304	63716327	15	-	27260156	BXPC3	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.580057705599681	[965]	[852,558,552,723]	-8	hSpCas9	negative selection	5611553
63775171	63775194	15	-	27260156	A673	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.3030167221932536	[144]	[168,131,151,112]	-6	hSpCas9	negative selection	5668543
63716418	63716441	15	+	27260156	A673	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.6812422266419307	[194]	[159,112,167,144]	-9	hSpCas9	negative selection	5668544
63775052	63775075	15	+	27260156	A673	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.427644145012142	[609]	[609,529,419,630]	-8	hSpCas9	negative selection	5668545
63716304	63716327	15	-	27260156	A673	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.8647012920771984	[965]	[546,723,728,526]	-9	hSpCas9	negative selection	5732804
63775171	63775194	15	-	27260156	A375	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.42421216456334054	[144]	[120,123,67,183]	-5	hSpCas9	negative selection	5789794
63716418	63716441	15	+	27260156	A375	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.8753693603432489	[194]	[124,119,111,136]	-8	hSpCas9	negative selection	5789795
63775052	63775075	15	+	27260156	A375	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.04072695198425036	[609]	[812,849,775,530]	0	hSpCas9	negative selection	5789796
63716304	63716327	15	-	27260156	A375	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.31263921784007653	[965]	[1006,946,1167,556]	-4	hSpCas9	negative selection	5854055
63775171	63775194	15	-	27260156	COLO741	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.2620583816705784	[144]	[180,180,106]	-5	hSpCas9	negative selection	5911045
63716418	63716441	15	+	27260156	COLO741	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.5306659325791803	[194]	[169,134,208]	-8	hSpCas9	negative selection	5911046
63775052	63775075	15	+	27260156	COLO741	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.2475659701822518	[609]	[752,635,591]	-5	hSpCas9	negative selection	5911047
63716304	63716327	15	-	27260156	COLO741	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.6508847864146706	[965]	[613,812,905]	-8	hSpCas9	negative selection	5975306
63775171	63775194	15	-	27260156	CAL120	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.7979294709103821	[144]	[149,105,62]	-8	hSpCas9	negative selection	6032296
63716418	63716441	15	+	27260156	CAL120	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.3967323469348305	[194]	[152,201,192]	-5	hSpCas9	negative selection	6032297
63775052	63775075	15	+	27260156	CAL120	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.14353045808050985	[609]	[869,542,675]	-2	hSpCas9	negative selection	6032298
63716304	63716327	15	-	27260156	CAL120	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.8379277641364475	[965]	[739,649,637]	-8	hSpCas9	negative selection	6096557
63775171	63775194	15	-	27260156	CADOES1	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.5960516405454639	[144]	[64,322,121,309]	8	hSpCas9	negative selection	6153547
63716418	63716441	15	+	27260156	CADOES1	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.152756032530742	[194]	[240,151,141,273]	2	hSpCas9	negative selection	6153548
63775052	63775075	15	+	27260156	CADOES1	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.05525857462431588	[609]	[539,442,446,761]	-1	hSpCas9	negative selection	6153549
63716304	63716327	15	-	27260156	CADOES1	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.4782748819896576	[965]	[634,664,552,729]	-7	hSpCas9	negative selection	6217808
63775171	63775194	15	-	27260156	EWS502	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.05307963444861352	[144]	[150,55,212,177]	-1	hSpCas9	negative selection	6274798
63716418	63716441	15	+	27260156	EWS502	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.2792933431547058	[194]	[82,246,167,190]	-5	hSpCas9	negative selection	6274799
63775052	63775075	15	+	27260156	EWS502	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.19942052693104745	[609]	[683,569,777,962]	3	hSpCas9	negative selection	6274800
63716304	63716327	15	-	27260156	EWS502	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7498607478780233	[965]	[450,654,548,806]	-8	hSpCas9	negative selection	6339059
63775171	63775194	15	-	27260156	EW8	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.13706528199600343	[144]	[88,73,153,99]	-3	hSpCas9	negative selection	6396049
63716418	63716441	15	+	27260156	EW8	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.20495483467753872	[194]	[105,199,106,136]	-4	hSpCas9	negative selection	6396050
63775052	63775075	15	+	27260156	EW8	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.04358521004348481	[609]	[469,455,526,454]	-1	hSpCas9	negative selection	6396051
63716304	63716327	15	-	27260156	EW8	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7726620854914438	[965]	[407,331,493,584]	-8	hSpCas9	negative selection	6460310
63775171	63775194	15	-	27260156	CORL105	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.29892747534111264	[144]	[196,302,162,162]	5	hSpCas9	negative selection	6517300
63716418	63716441	15	+	27260156	CORL105	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.3876988672054116	[194]	[272,101,181,146]	-6	hSpCas9	negative selection	6517301
63775052	63775075	15	+	27260156	CORL105	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.05947034295494963	[609]	[521,585,960,935]	1	hSpCas9	negative selection	6517302
63716304	63716327	15	-	27260156	CORL105	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7492938461574679	[965]	[836,556,685,620]	-8	hSpCas9	negative selection	6581561
63775171	63775194	15	-	27260156	HS294T	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.4333838348430574	[144]	[25,46,43,51]	-6	hSpCas9	negative selection	6638551
63716418	63716441	15	+	27260156	HS294T	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.30339381428109813	[194]	[83,34,56,67]	-4	hSpCas9	negative selection	6638552
63775052	63775075	15	+	27260156	HS294T	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.11000396516539485	[609]	[186,220,211,263]	-1	hSpCas9	negative selection	6638553
63716304	63716327	15	-	27260156	HS294T	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7621481178286467	[965]	[290,153,162,276]	-8	hSpCas9	negative selection	6702812
63775171	63775194	15	-	27260156	HCC44	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.2573757742327183	[144]	[197,99,361,165]	4	hSpCas9	negative selection	6759802
63716418	63716441	15	+	27260156	HCC44	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.7467985006336575	[194]	[83,151,232,67]	-8	hSpCas9	negative selection	6759803
63775052	63775075	15	+	27260156	HCC44	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.10258931693917867	[609]	[753,547,895,811]	1	hSpCas9	negative selection	6759804
63716304	63716327	15	-	27260156	HCC44	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7627660212901104	[965]	[808,536,850,445]	-8	hSpCas9	negative selection	6824063
63775171	63775194	15	-	27260156	G402	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.3561962035455186	[144]	[420,178,180,152]	4	hSpCas9	negative selection	6881053
63716418	63716441	15	+	27260156	G402	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.9227542018540482	[194]	[102,141,122,130]	-8	hSpCas9	negative selection	6881054
63775052	63775075	15	+	27260156	G402	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.2118606588170016	[609]	[777,591,759,1266]	2	hSpCas9	negative selection	6881055
63716304	63716327	15	-	27260156	G402	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.21193022869695466	[965]	[1285,876,1396,559]	-3	hSpCas9	negative selection	6945314
63775171	63775194	15	-	27260156	L33	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.31016749103296837	[144]	[125,63,115,252]	6	hSpCas9	negative selection	7002304
63716418	63716441	15	+	27260156	L33	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.06799683586080096	[194]	[231,77,100,159]	-1	hSpCas9	negative selection	7002305
63775052	63775075	15	+	27260156	L33	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.0957027903207201	[609]	[549,255,394,804]	2	hSpCas9	negative selection	7002306
63716304	63716327	15	-	27260156	L33	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.9439528872368175	[965]	[540,201,345,423]	-9	hSpCas9	negative selection	7066565
63775171	63775194	15	-	27260156	K562	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.25845998844652973	[144]	[108,66,391,50]	3	hSpCas9	negative selection	7123555
63716418	63716441	15	+	27260156	K562	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.8947264955110443	[194]	[34,229,97,19]	-7	hSpCas9	negative selection	7123556
63775052	63775075	15	+	27260156	K562	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.17744892950022834	[609]	[719,464,732,537]	2	hSpCas9	negative selection	7123557
63716304	63716327	15	-	27260156	K562	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.8365732650375151	[965]	[403,801,423,317]	-7	hSpCas9	negative selection	7187816
63775171	63775194	15	-	27260156	HT29	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.09437156020684423	[144]	[199,206,115,144]	-2	hSpCas9	negative selection	7244806
63716418	63716441	15	+	27260156	HT29	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.25493422230251195	[194]	[202,155,170,252]	-5	hSpCas9	negative selection	7244807
63775052	63775075	15	+	27260156	HT29	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.28692864596545725	[609]	[1070,763,1026,767]	5	hSpCas9	negative selection	7244808
63716304	63716327	15	-	27260156	HT29	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.4832074810993996	[965]	[985,759,857,763]	-7	hSpCas9	negative selection	7309067
63775171	63775194	15	-	27260156	MHHES1	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.5475733482069303	[144]	[174,193,326,240]	8	hSpCas9	negative selection	7366057
63716418	63716441	15	+	27260156	MHHES1	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.637829243786882	[194]	[99,131,249,86]	-8	hSpCas9	negative selection	7366058
63775052	63775075	15	+	27260156	MHHES1	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.011208871342984372	[609]	[557,708,769,665]	0	hSpCas9	negative selection	7366059
63716304	63716327	15	-	27260156	MHHES1	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7225836735101889	[965]	[1013,642,632,427]	-8	hSpCas9	negative selection	7430318
63775171	63775194	15	-	27260156	MEWO	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.012682848268595892	[144]	[174,120,121]	0	hSpCas9	negative selection	7487308
63716418	63716441	15	+	27260156	MEWO	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.10918175001009356	[194]	[170,114,221]	-2	hSpCas9	negative selection	7487309
63775052	63775075	15	+	27260156	MEWO	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.1469847199622984	[609]	[755,550,612]	3	hSpCas9	negative selection	7487310
63716304	63716327	15	-	27260156	MEWO	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7233030856051714	[965]	[768,555,359]	-9	hSpCas9	negative selection	7551569
63775171	63775194	15	-	27260156	LNCAPCLONEFGC	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.41091852720612243	[144]	[176,206,253,69]	6	hSpCas9	negative selection	7608559
63716418	63716441	15	+	27260156	LNCAPCLONEFGC	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.20219324423116225	[194]	[186,215,90,105]	-3	hSpCas9	negative selection	7608560
63775052	63775075	15	+	27260156	LNCAPCLONEFGC	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.23779054355370527	[609]	[761,506,817,550]	3	hSpCas9	negative selection	7608561
63716304	63716327	15	-	27260156	LNCAPCLONEFGC	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.530648902795604	[965]	[567,447,667,758]	-7	hSpCas9	negative selection	7672820
63775171	63775194	15	-	27260156	PANC0327	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-1.1204115114620805	[144]	[26,99,29,71]	-8	hSpCas9	negative selection	7729810
63716418	63716441	15	+	27260156	PANC0327	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.12868679352036505	[194]	[273,228,75,54]	-2	hSpCas9	negative selection	7729811
63775052	63775075	15	+	27260156	PANC0327	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.09359115436097398	[609]	[496,930,332,498]	1	hSpCas9	negative selection	7729812
63716304	63716327	15	-	27260156	PANC0327	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.5592770428498286	[965]	[563,496,730,546]	-7	hSpCas9	negative selection	7794071
63775171	63775194	15	-	27260156	NCIH2009	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.23906134722788863	[144]	[184,249,270]	3	hSpCas9	negative selection	7851061
63716418	63716441	15	+	27260156	NCIH2009	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.009646264057261877	[194]	[465,232,161]	0	hSpCas9	negative selection	7851062
63775052	63775075	15	+	27260156	NCIH2009	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.0010995133635435805	[609]	[938,759,876]	0	hSpCas9	negative selection	7851063
63716304	63716327	15	-	27260156	NCIH2009	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.971946347182149	[965]	[784,534,764]	-8	hSpCas9	negative selection	7915322
63775171	63775194	15	-	27260156	NCIH1373	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.45259374164108435	[144]	[68,221,244,87]	4	hSpCas9	negative selection	7972312
63716418	63716441	15	+	27260156	NCIH1373	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.8991385713638189	[194]	[52,158,119,31]	-7	hSpCas9	negative selection	7972313
63775052	63775075	15	+	27260156	NCIH1373	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.29277834836828137	[609]	[1160,712,767,200]	3	hSpCas9	negative selection	7972314
63716304	63716327	15	-	27260156	NCIH1373	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7180322346431358	[965]	[883,719,274,208]	-6	hSpCas9	negative selection	8036573
63775171	63775194	15	-	27260156	PATU8902	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.6573407772844533	[144]	[256,68,151,10]	-6	hSpCas9	negative selection	8093563
63716418	63716441	15	+	27260156	PATU8902	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.017744030373137765	[194]	[206,218,276,410]	0	hSpCas9	negative selection	8093564
63775052	63775075	15	+	27260156	PATU8902	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.06476476121378605	[609]	[859,1211,708,803]	0	hSpCas9	negative selection	8093565
63716304	63716327	15	-	27260156	PATU8902	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7685199614867626	[965]	[849,682,663,1013]	-6	hSpCas9	negative selection	8157824
63775171	63775194	15	-	27260156	PANC1	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.019556383065896688	[144]	[152,186,86,92]	0	hSpCas9	negative selection	8214814
63716418	63716441	15	+	27260156	PANC1	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	0.13298141591042412	[194]	[153,242,214,139]	2	hSpCas9	negative selection	8214815
63775052	63775075	15	+	27260156	PANC1	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.11977467097087274	[609]	[527,819,608,392]	2	hSpCas9	negative selection	8214816
63716304	63716327	15	-	27260156	PANC1	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.6197822270798808	[965]	[477,634,581,485]	-7	hSpCas9	negative selection	8279075
63775171	63775194	15	-	27260156	PANC0813	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.4836945316779444	[144]	[294,170,293,199]	7	hSpCas9	negative selection	8336065
63716418	63716441	15	+	27260156	PANC0813	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.31532265308801866	[194]	[271,216,128,128]	-5	hSpCas9	negative selection	8336066
63775052	63775075	15	+	27260156	PANC0813	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.1569670081968088	[609]	[917,487,839,950]	2	hSpCas9	negative selection	8336067
63716304	63716327	15	-	27260156	PANC0813	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7543455043968883	[965]	[668,978,408,632]	-8	hSpCas9	negative selection	8400326
63775171	63775194	15	-	27260156	RDES	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.09376735271499514	[144]	[143,128,221,233]	1	hSpCas9	negative selection	8457316
63716418	63716441	15	+	27260156	RDES	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.5915589200523355	[194]	[129,79,219,178]	-7	hSpCas9	negative selection	8457317
63775052	63775075	15	+	27260156	RDES	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.12632453397532023	[609]	[580,727,890,910]	2	hSpCas9	negative selection	8457318
63716304	63716327	15	-	27260156	RDES	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.5834400137242711	[965]	[559,711,644,1123]	-7	hSpCas9	negative selection	8521577
63775171	63775194	15	-	27260156	PC3	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	-0.33002404701264787	[144]	[48,162,218,85]	-6	hSpCas9	negative selection	8578567
63716418	63716441	15	+	27260156	PC3	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.4426898404961397	[194]	[88,158,217,143]	-7	hSpCas9	negative selection	8578568
63775052	63775075	15	+	27260156	PC3	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.15933582725885348	[609]	[497,577,1173,667]	3	hSpCas9	negative selection	8578569
63716304	63716327	15	-	27260156	PC3	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.6563516187917207	[965]	[401,541,1339,471]	-9	hSpCas9	negative selection	8642828
63775171	63775194	15	-	27260156	PATU8988T	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.033995375114976634	[144]	[61,200,130,188]	0	hSpCas9	negative selection	8699818
63716418	63716441	15	+	27260156	PATU8988T	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.2335269166190519	[194]	[167,196,129,148]	-4	hSpCas9	negative selection	8699819
63775052	63775075	15	+	27260156	PATU8988T	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.25153198767606494	[609]	[850,748,558,649]	4	hSpCas9	negative selection	8699820
63716304	63716327	15	-	27260156	PATU8988T	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.600434163349316	[965]	[585,544,674,651]	-7	hSpCas9	negative selection	8764079
63775171	63775194	15	-	27260156	T47D	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.04059503576504819	[144]	[269,124,115,189]	0	hSpCas9	negative selection	8821069
63716418	63716441	15	+	27260156	T47D	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.6675766405768657	[194]	[131,144,144,149]	-8	hSpCas9	negative selection	8821070
63775052	63775075	15	+	27260156	T47D	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.005888224308597534	[609]	[774,675,749,653]	0	hSpCas9	negative selection	8821071
63716304	63716327	15	-	27260156	T47D	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.5955337921202181	[965]	[816,774,704,677]	-8	hSpCas9	negative selection	8885330
63775171	63775194	15	-	27260156	SU8686	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.3372188469873998	[144]	[149,146,239,200]	6	hSpCas9	negative selection	8942320
63716418	63716441	15	+	27260156	SU8686	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.16125935500220856	[194]	[205,165,131,183]	-3	hSpCas9	negative selection	8942321
63775052	63775075	15	+	27260156	SU8686	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.020149246758290607	[609]	[488,604,641,750]	0	hSpCas9	negative selection	8942322
63716304	63716327	15	-	27260156	SU8686	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.8814063970174425	[965]	[522,423,509,651]	-8	hSpCas9	negative selection	9006581
63775171	63775194	15	-	27260156	SKES1	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.29960669934192175	[144]	[152,321,160,97]	6	hSpCas9	negative selection	9063571
63716418	63716441	15	+	27260156	SKES1	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.46712156320844667	[194]	[211,142,134,87]	-8	hSpCas9	negative selection	9063572
63775052	63775075	15	+	27260156	SKES1	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.37612676050948074	[609]	[932,775,688,773]	7	hSpCas9	negative selection	9063573
63716304	63716327	15	-	27260156	SKES1	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.907099422766472	[965]	[810,479,397,411]	-9	hSpCas9	negative selection	9127832
63775171	63775194	15	-	27260156	TOV112D	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.3809295494305456	[144]	[348,199,96,127]	7	hSpCas9	negative selection	9184822
63716418	63716441	15	+	27260156	TOV112D	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.583327017025679	[194]	[79,192,115,142]	-8	hSpCas9	negative selection	9184823
63775052	63775075	15	+	27260156	TOV112D	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-0.09757723118463757	[609]	[673,738,383,536]	-2	hSpCas9	negative selection	9184824
63716304	63716327	15	-	27260156	TOV112D	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.5543955757548212	[965]	[888,500,576,647]	-8	hSpCas9	negative selection	9249083
63775171	63775194	15	-	27260156	TC71	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.004265803356754416	[144]	[169,130,174,145]	0	hSpCas9	negative selection	9306073
63716418	63716441	15	+	27260156	TC71	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.2734020328600508	[194]	[149,204,169,166]	-6	hSpCas9	negative selection	9306074
63775052	63775075	15	+	27260156	TC71	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.14334486625165638	[609]	[772,728,589,804]	3	hSpCas9	negative selection	9306075
63716304	63716327	15	-	27260156	TC71	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7158102901338215	[965]	[547,641,634,702]	-9	hSpCas9	negative selection	9370334
63775171	63775194	15	-	27260156	TC32	viability	ATTCTGTTAGTGAACGCCCCCGG	HERC1	ENSG00000103657	0.11556548810304368	[144]	[134,64,315,127]	2	hSpCas9	negative selection	9427324
63716418	63716441	15	+	27260156	TC32	viability	CGAGTAAATGAATGCTCCTGAGG	HERC1	ENSG00000103657	-0.9360111359754699	[194]	[167,55,58,92]	-9	hSpCas9	negative selection	9427325
63775052	63775075	15	+	27260156	TC32	viability	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	0.21653986503176365	[609]	[580,672,767,621]	4	hSpCas9	negative selection	9427326
63716304	63716327	15	-	27260156	TC32	viability	GAACATGAAGTGATGACAGCTGG	HERC1	ENSG00000103657	-0.7033734714234291	[965]	[541,527,605,537]	-8	hSpCas9	negative selection	9491585
63747013	63747036	15	+	27869803	HPAFII	viability after 27 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.525834743188669	[238]	[151,204,NaN]	4	hSpCas9	negative selection	9554255
63749475	63749498	15	-	27869803	HPAFII	viability after 27 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.4554380487424259	[238]	[131,57,NaN]	-3	hSpCas9	negative selection	9554256
63756681	63756704	15	-	27869803	HPAFII	viability after 27 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.2191208562739284	[534]	[143,322,NaN]	-2	hSpCas9	negative selection	9554257
63758277	63758300	15	+	27869803	HPAFII	viability after 27 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.5329778994296267	[358]	[343,213,NaN]	4	hSpCas9	negative selection	9554258
63764139	63764162	15	-	27869803	HPAFII	viability after 27 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.342817339871577	[74]	[32,0,NaN]	-7	hSpCas9	negative selection	9554259
63775052	63775075	15	+	27869803	HPAFII	viability after 27 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.7159551008736678	[408]	[23,99,NaN]	-8	hSpCas9	negative selection	9554260
63747013	63747036	15	+	27869803	HPAFII	viability after 15 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.297293204780774	[238]	[380,274,NaN]	3	hSpCas9	negative selection	9636704
63749475	63749498	15	-	27869803	HPAFII	viability after 15 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.6647079020713106	[238]	[145,171,NaN]	-6	hSpCas9	negative selection	9636705
63756681	63756704	15	-	27869803	HPAFII	viability after 15 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.0902611426108264	[534]	[639,477,NaN]	-1	hSpCas9	negative selection	9636706
63758277	63758300	15	+	27869803	HPAFII	viability after 15 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.9276864952362501	[358]	[884,639,NaN]	8	hSpCas9	negative selection	9636707
63764139	63764162	15	-	27869803	HPAFII	viability after 15 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.1754549668698842	[74]	[76,9,NaN]	-8	hSpCas9	negative selection	9636708
63775052	63775075	15	+	27869803	HPAFII	viability after 15 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.01441531259562	[408]	[187,235,NaN]	-7	hSpCas9	negative selection	9636709
63747013	63747036	15	+	27869803	ASPC1	viability after 36 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.4153409444387808	[630]	[43,268,165]	-4	hSpCas9	negative selection	9719153
63749475	63749498	15	-	27869803	ASPC1	viability after 36 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.03767452017051465	[445]	[125,340,37]	0	hSpCas9	negative selection	9719154
63756681	63756704	15	-	27869803	ASPC1	viability after 36 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.862794277003511	[1145]	[1251,715,360]	8	hSpCas9	negative selection	9719155
63758277	63758300	15	+	27869803	ASPC1	viability after 36 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.5256525270971263	[1217]	[351,1076,418]	5	hSpCas9	negative selection	9719156
63764139	63764162	15	-	27869803	ASPC1	viability after 36 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.0952286775324045	[187]	[25,94,58]	-1	hSpCas9	negative selection	9719157
63775052	63775075	15	+	27869803	ASPC1	viability after 36 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	1.0359439804524213	[642]	[465,437,468]	8	hSpCas9	negative selection	9719158
63747013	63747036	15	+	27869803	PATU8988S	viability after 35 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	-0.03899887067337117	[543]	[104,321,NaN]	0	hSpCas9	negative selection	9801602
63749475	63749498	15	-	27869803	PATU8988S	viability after 35 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.9092959271132752	[370]	[104,53,NaN]	-7	hSpCas9	negative selection	9801603
63756681	63756704	15	-	27869803	PATU8988S	viability after 35 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.8847572120277104	[983]	[271,156,NaN]	-7	hSpCas9	negative selection	9801604
63758277	63758300	15	+	27869803	PATU8988S	viability after 35 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.5793910778620235	[1212]	[720,738,NaN]	6	hSpCas9	negative selection	9801605
63764139	63764162	15	-	27869803	PATU8988S	viability after 35 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.297550261705003	[159]	[21,82,NaN]	-3	hSpCas9	negative selection	9801606
63775052	63775075	15	+	27869803	PATU8988S	viability after 35 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.0679237139809816	[644]	[85,161,NaN]	-7	hSpCas9	negative selection	9801607
63747013	63747036	15	+	27869803	PATU8988S	viability after 31 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.042161668140973496	[543]	[170,289,NaN]	0	hSpCas9	negative selection	9884051
63749475	63749498	15	-	27869803	PATU8988S	viability after 31 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	-0.8724762127186141	[370]	[93,63,NaN]	-7	hSpCas9	negative selection	9884052
63756681	63756704	15	-	27869803	PATU8988S	viability after 31 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	-0.4896764588434747	[983]	[256,307,NaN]	-5	hSpCas9	negative selection	9884053
63758277	63758300	15	+	27869803	PATU8988S	viability after 31 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.5598386813755067	[1212]	[657,782,NaN]	6	hSpCas9	negative selection	9884054
63764139	63764162	15	-	27869803	PATU8988S	viability after 31 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.5114075567666896	[159]	[31,60,NaN]	-5	hSpCas9	negative selection	9884055
63775052	63775075	15	+	27869803	PATU8988S	viability after 31 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.2352660656608268	[644]	[132,78,NaN]	-8	hSpCas9	negative selection	9884056
63747013	63747036	15	+	27869803	HPAFII	viability after 35 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.5545825854299049	[238]	[61,307,NaN]	3	hSpCas9	negative selection	9966500
63749475	63749498	15	-	27869803	HPAFII	viability after 35 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.22335907997566198	[238]	[176,100,NaN]	1	hSpCas9	negative selection	9966501
63756681	63756704	15	-	27869803	HPAFII	viability after 35 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.11560898702879019	[534]	[228,365,NaN]	0	hSpCas9	negative selection	9966502
63758277	63758300	15	+	27869803	HPAFII	viability after 35 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.2414066176526264	[358]	[259,163,NaN]	1	hSpCas9	negative selection	9966503
63764139	63764162	15	-	27869803	HPAFII	viability after 35 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.41174078499786293	[74]	[52,0,NaN]	-3	hSpCas9	negative selection	9966504
63775052	63775075	15	+	27869803	HPAFII	viability after 35 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.6825086177805257	[408]	[16,117,NaN]	-7	hSpCas9	negative selection	9966505
63747013	63747036	15	+	27869803	HPAFII	viability after 31 days	CTCCCGCAAGTGCAAGAGCAAGG	HERC1	ENSG00000103657	0.18022850334145335	[238]	[50,261,NaN]	1	hSpCas9	negative selection	10048949
63749475	63749498	15	-	27869803	HPAFII	viability after 31 days	TGTGGTCAGGGAAATTCCACAGG	HERC1	ENSG00000103657	0.2535949651556418	[238]	[235,76,NaN]	1	hSpCas9	negative selection	10048950
63756681	63756704	15	-	27869803	HPAFII	viability after 31 days	TCTGTTAGAGCTTGCGGGAAAGG	HERC1	ENSG00000103657	0.10146893544613889	[534]	[257,391,NaN]	0	hSpCas9	negative selection	10048951
63758277	63758300	15	+	27869803	HPAFII	viability after 31 days	CTCACAGGTTTCGGAGACAATGG	HERC1	ENSG00000103657	0.6957442407071509	[358]	[411,232,NaN]	5	hSpCas9	negative selection	10048952
63764139	63764162	15	-	27869803	HPAFII	viability after 31 days	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.9482461609687383	[74]	[19,0,NaN]	-8	hSpCas9	negative selection	10048953
63775052	63775075	15	+	27869803	HPAFII	viability after 31 days	TCGTTGCAAAGACTGAGACCAGG	HERC1	ENSG00000103657	-1.138781111789449	[408]	[64,146,NaN]	-6	hSpCas9	negative selection	10048954
63775272	63775295	15	+	28162770	P31FUJ	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-1.2602829408364853	[52]	[25]	-7	hSpCas9	negative selection	10168363
63727657	63727680	15	-	28162770	P31FUJ	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	-0.48216167335109583	[629]	[529]	-4	hSpCas9	negative selection	10168364
63727719	63727742	15	+	28162770	P31FUJ	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-2.2638291000350033	[93]	[22]	-8	hSpCas9	negative selection	10168365
63716332	63716355	15	-	28162770	P31FUJ	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-4.4807297178579635	[18]	[0]	-9	hSpCas9	negative selection	10168366
63636003	63636026	15	-	28162770	P31FUJ	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	-1.1027416638500056	[52]	[28]	-6	hSpCas9	negative selection	10168367
63623759	63623782	15	-	28162770	P31FUJ	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-1.1462932111597037	[355]	[188]	-7	hSpCas9	negative selection	10168368
63775554	63775577	15	-	28162770	P31FUJ	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	-1.559966947667888	[413]	[164]	-7	hSpCas9	negative selection	10168369
63764139	63764162	15	-	28162770	P31FUJ	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.8177647051355348	[23]	[7]	-8	hSpCas9	negative selection	10168370
63747055	63747078	15	+	28162770	P31FUJ	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	-1.9636155715989896	[155]	[46]	-8	hSpCas9	negative selection	10168371
63775272	63775295	15	+	28162770	TF1	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10337729
63727657	63727680	15	-	28162770	TF1	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	NaN	[NaN]	[330]	1	hSpCas9	negative selection	10337730
63727719	63727742	15	+	28162770	TF1	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	NaN	[NaN]	[28]	1	hSpCas9	negative selection	10337731
63716332	63716355	15	-	28162770	TF1	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10337732
63636003	63636026	15	-	28162770	TF1	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10337733
63623759	63623782	15	-	28162770	TF1	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	NaN	[NaN]	[74]	1	hSpCas9	negative selection	10337734
63775554	63775577	15	-	28162770	TF1	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10337735
63764139	63764162	15	-	28162770	TF1	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	NaN	[NaN]	[56]	1	hSpCas9	negative selection	10337736
63747055	63747078	15	+	28162770	TF1	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10337737
63775272	63775295	15	+	28162770	SKM1	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.9919266994643179	[17]	[15]	-6	hSpCas9	negative selection	10507095
63727657	63727680	15	-	28162770	SKM1	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.6654442967848884	[101]	[285]	6	hSpCas9	negative selection	10507096
63727719	63727742	15	+	28162770	SKM1	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-0.3674358345565243	[26]	[36]	-3	hSpCas9	negative selection	10507097
63716332	63716355	15	-	28162770	SKM1	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-3.4069641987431614	[11]	[1]	-9	hSpCas9	negative selection	10507098
63636003	63636026	15	-	28162770	SKM1	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	-0.18973348252249256	[19]	[30]	-2	hSpCas9	negative selection	10507099
63623759	63623782	15	-	28162770	SKM1	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.2729162336294459	[94]	[138]	-2	hSpCas9	negative selection	10507100
63775554	63775577	15	-	28162770	SKM1	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.31405985155402294	[90]	[199]	3	hSpCas9	negative selection	10507101
63764139	63764162	15	-	28162770	SKM1	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.5000736031346436	[7]	[4]	-7	hSpCas9	negative selection	10507102
63747055	63747078	15	+	28162770	SKM1	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.25816865066197797	[34]	[73]	2	hSpCas9	negative selection	10507103
63775272	63775295	15	+	28162770	SKM1	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.9919266994643179	[17]	[15]	-6	hSpCas9	negative selection	10676461
63727657	63727680	15	-	28162770	SKM1	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.6654442967848884	[101]	[285]	6	hSpCas9	negative selection	10676462
63727719	63727742	15	+	28162770	SKM1	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-0.3674358345565243	[26]	[36]	-3	hSpCas9	negative selection	10676463
63716332	63716355	15	-	28162770	SKM1	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-3.4069641987431614	[11]	[1]	-9	hSpCas9	negative selection	10676464
63636003	63636026	15	-	28162770	SKM1	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	-0.18973348252249256	[19]	[30]	-2	hSpCas9	negative selection	10676465
63623759	63623782	15	-	28162770	SKM1	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.2729162336294459	[94]	[138]	-2	hSpCas9	negative selection	10676466
63775554	63775577	15	-	28162770	SKM1	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.31405985155402294	[90]	[199]	3	hSpCas9	negative selection	10676467
63764139	63764162	15	-	28162770	SKM1	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.5000736031346436	[7]	[4]	-7	hSpCas9	negative selection	10676468
63747055	63747078	15	+	28162770	SKM1	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.25816865066197797	[34]	[73]	2	hSpCas9	negative selection	10676469
63775272	63775295	15	+	28162770	PL21	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.654009519047225	[46]	[12]	-4	hSpCas9	negative selection	10845827
63727657	63727680	15	-	28162770	PL21	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	1.2655420897109597	[344]	[360]	9	hSpCas9	negative selection	10845828
63727719	63727742	15	+	28162770	PL21	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	0.9507801455526028	[125]	[105]	7	hSpCas9	negative selection	10845829
63716332	63716355	15	-	28162770	PL21	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-2.5003001036517727	[51]	[3]	-9	hSpCas9	negative selection	10845830
63636003	63636026	15	-	28162770	PL21	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	-0.7123975442603403	[63]	[16]	-5	hSpCas9	negative selection	10845831
63623759	63623782	15	-	28162770	PL21	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.38482288623183625	[290]	[96]	-3	hSpCas9	negative selection	10845832
63775554	63775577	15	-	28162770	PL21	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.8695689047213525	[292]	[232]	7	hSpCas9	negative selection	10845833
63764139	63764162	15	-	28162770	PL21	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.9697853869529922	[8]	[0]	-8	hSpCas9	negative selection	10845834
63747055	63747078	15	+	28162770	PL21	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.8246304793971138	[95]	[73]	7	hSpCas9	negative selection	10845835
63775272	63775295	15	+	28162770	P31FUJ	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-1.2602829408364853	[52]	[25]	-7	hSpCas9	negative selection	11015193
63727657	63727680	15	-	28162770	P31FUJ	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	-0.48216167335109583	[629]	[529]	-4	hSpCas9	negative selection	11015194
63727719	63727742	15	+	28162770	P31FUJ	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-2.2638291000350033	[93]	[22]	-8	hSpCas9	negative selection	11015195
63716332	63716355	15	-	28162770	P31FUJ	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-4.4807297178579635	[18]	[0]	-9	hSpCas9	negative selection	11015196
63636003	63636026	15	-	28162770	P31FUJ	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	-1.1027416638500056	[52]	[28]	-6	hSpCas9	negative selection	11015197
63623759	63623782	15	-	28162770	P31FUJ	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-1.1462932111597037	[355]	[188]	-7	hSpCas9	negative selection	11015198
63775554	63775577	15	-	28162770	P31FUJ	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	-1.559966947667888	[413]	[164]	-7	hSpCas9	negative selection	11015199
63764139	63764162	15	-	28162770	P31FUJ	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.8177647051355348	[23]	[7]	-8	hSpCas9	negative selection	11015200
63747055	63747078	15	+	28162770	P31FUJ	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	-1.9636155715989896	[155]	[46]	-8	hSpCas9	negative selection	11015201
63775272	63775295	15	+	28162770	OCIAML5	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.08653182450101982	[19]	[33]	0	hSpCas9	negative selection	11184559
63727657	63727680	15	-	28162770	OCIAML5	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.5494786920867336	[281]	[744]	5	hSpCas9	negative selection	11184560
63727719	63727742	15	+	28162770	OCIAML5	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	0.38894152863979803	[54]	[129]	3	hSpCas9	negative selection	11184561
63716332	63716355	15	-	28162770	OCIAML5	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-5.852066570863997	[31]	[0]	-9	hSpCas9	negative selection	11184562
63636003	63636026	15	-	28162770	OCIAML5	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	0.04483993617189963	[28]	[53]	0	hSpCas9	negative selection	11184563
63623759	63623782	15	-	28162770	OCIAML5	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	0.824856234195148	[156]	[501]	7	hSpCas9	negative selection	11184564
63775554	63775577	15	-	28162770	OCIAML5	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.5459329980583093	[180]	[476]	5	hSpCas9	negative selection	11184565
63764139	63764162	15	-	28162770	OCIAML5	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.7906660261998537	[22]	[11]	-7	hSpCas9	negative selection	11184566
63747055	63747078	15	+	28162770	OCIAML5	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.21206376655571868	[76]	[160]	1	hSpCas9	negative selection	11184567
63775272	63775295	15	+	28162770	EOL1	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	1.4613011792490707	[70]	[102]	9	hSpCas9	negative selection	11353925
63727657	63727680	15	-	28162770	EOL1	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.47539392735962094	[541]	[396]	4	hSpCas9	negative selection	11353926
63727719	63727742	15	+	28162770	EOL1	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-0.17394209182882892	[196]	[91]	-1	hSpCas9	negative selection	11353927
63716332	63716355	15	-	28162770	EOL1	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-5.141541418887238	[66]	[0]	-9	hSpCas9	negative selection	11353928
63636003	63636026	15	-	28162770	EOL1	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	0.09342468357998068	[152]	[85]	0	hSpCas9	negative selection	11353929
63623759	63623782	15	-	28162770	EOL1	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	1.0102776455964184	[293]	[311]	8	hSpCas9	negative selection	11353930
63775554	63775577	15	-	28162770	EOL1	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.15729961046828567	[336]	[197]	1	hSpCas9	negative selection	11353931
63764139	63764162	15	-	28162770	EOL1	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	1.20465569076327	[27]	[33]	8	hSpCas9	negative selection	11353932
63747055	63747078	15	+	28162770	EOL1	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.19490551821018742	[130]	[78]	1	hSpCas9	negative selection	11353933
63775272	63775295	15	+	28162770	MOLM13	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.43900121406393966	[59]	[31]	-3	hSpCas9	negative selection	11523291
63727657	63727680	15	-	28162770	MOLM13	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.6396843703399374	[513]	[578]	5	hSpCas9	negative selection	11523292
63727719	63727742	15	+	28162770	MOLM13	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	-0.2579356550164271	[171]	[103]	-1	hSpCas9	negative selection	11523293
63716332	63716355	15	-	28162770	MOLM13	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-4.924428041234182	[41]	[0]	-9	hSpCas9	negative selection	11523294
63636003	63636026	15	-	28162770	MOLM13	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	0.9306236228547189	[118]	[163]	7	hSpCas9	negative selection	11523295
63623759	63623782	15	-	28162770	MOLM13	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.26092537150076345	[352]	[212]	-1	hSpCas9	negative selection	11523296
63775554	63775577	15	-	28162770	MOLM13	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	-1.7072817894636925	[550]	[121]	-7	hSpCas9	negative selection	11523297
63764139	63764162	15	-	28162770	MOLM13	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.5321106184554214	[59]	[29]	-3	hSpCas9	negative selection	11523298
63747055	63747078	15	+	28162770	MOLM13	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.5122835009030324	[159]	[164]	4	hSpCas9	negative selection	11523299
63775272	63775295	15	+	28162770	HEL	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.04633207206153789	[78]	[48]	0	hSpCas9	negative selection	11692657
63727657	63727680	15	-	28162770	HEL	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.6301387952207234	[459]	[455]	5	hSpCas9	negative selection	11692658
63727719	63727742	15	+	28162770	HEL	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	0.747327733277557	[132]	[142]	6	hSpCas9	negative selection	11692659
63716332	63716355	15	-	28162770	HEL	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-4.971971012114851	[48]	[0]	-9	hSpCas9	negative selection	11692660
63636003	63636026	15	-	28162770	HEL	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	-0.8845081708645117	[97]	[33]	-5	hSpCas9	negative selection	11692661
63623759	63623782	15	-	28162770	HEL	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.19280563561036274	[322]	[180]	-1	hSpCas9	negative selection	11692662
63775554	63775577	15	-	28162770	HEL	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.03980978474975172	[403]	[265]	0	hSpCas9	negative selection	11692663
63764139	63764162	15	-	28162770	HEL	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.3572611679996434	[39]	[9]	-7	hSpCas9	negative selection	11692664
63747055	63747078	15	+	28162770	HEL	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	-0.9753905326559984	[131]	[42]	-6	hSpCas9	negative selection	11692665
63775272	63775295	15	+	28162770	MV411	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	0.0510403379792721	[54]	[47]	0	hSpCas9	negative selection	11862023
63727657	63727680	15	-	28162770	MV411	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.913513110448895	[316]	[502]	7	hSpCas9	negative selection	11862024
63727719	63727742	15	+	28162770	MV411	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	1.3694280751613856	[84]	[184]	9	hSpCas9	negative selection	11862025
63716332	63716355	15	-	28162770	MV411	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-5.074490544104587	[39]	[0]	-9	hSpCas9	negative selection	11862026
63636003	63636026	15	-	28162770	MV411	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	0.8324000515039316	[59]	[89]	7	hSpCas9	negative selection	11862027
63623759	63623782	15	-	28162770	MV411	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	0.7032549002039541	[217]	[298]	6	hSpCas9	negative selection	11862028
63775554	63775577	15	-	28162770	MV411	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.7635611751759335	[278]	[398]	7	hSpCas9	negative selection	11862029
63764139	63764162	15	-	28162770	MV411	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	0.24743755078277507	[14]	[14]	2	hSpCas9	negative selection	11862030
63747055	63747078	15	+	28162770	MV411	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	0.2884648190428303	[103]	[106]	2	hSpCas9	negative selection	11862031
63775272	63775295	15	+	28162770	MONOMAC1	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.2536203754259212	[25]	[24]	-2	hSpCas9	negative selection	12031389
63727657	63727680	15	-	28162770	MONOMAC1	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.07263501069638467	[252]	[304]	0	hSpCas9	negative selection	12031390
63727719	63727742	15	+	28162770	MONOMAC1	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	1.2906284523066875	[45]	[128]	9	hSpCas9	negative selection	12031391
63716332	63716355	15	-	28162770	MONOMAC1	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-2.78199934778071	[23]	[3]	-9	hSpCas9	negative selection	12031392
63636003	63636026	15	-	28162770	MONOMAC1	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	-0.08155962963961771	[59]	[64]	0	hSpCas9	negative selection	12031393
63623759	63623782	15	-	28162770	MONOMAC1	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.2634642087985296	[199]	[190]	-2	hSpCas9	negative selection	12031394
63775554	63775577	15	-	28162770	MONOMAC1	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	0.49437659529224487	[147]	[238]	5	hSpCas9	negative selection	12031395
63764139	63764162	15	-	28162770	MONOMAC1	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-0.7116100198893114	[9]	[6]	-5	hSpCas9	negative selection	12031396
63747055	63747078	15	+	28162770	MONOMAC1	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	1.3088540826704036	[74]	[212]	9	hSpCas9	negative selection	12031397
63775272	63775295	15	+	28162770	OCIAML2	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	-0.2689959640725106	[9]	[45]	-2	hSpCas9	negative selection	12200755
63727657	63727680	15	-	28162770	OCIAML2	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	0.2239571666534932	[56]	[368]	2	hSpCas9	negative selection	12200756
63727719	63727742	15	+	28162770	OCIAML2	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	0.9044096061047633	[7]	[82]	8	hSpCas9	negative selection	12200757
63716332	63716355	15	-	28162770	OCIAML2	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-5.792557920129523	[9]	[0]	-9	hSpCas9	negative selection	12200758
63636003	63636026	15	-	28162770	OCIAML2	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	2.5066500982577553	[5]	[188]	9	hSpCas9	negative selection	12200759
63623759	63623782	15	-	28162770	OCIAML2	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-1.0555923259633175	[50]	[135]	-6	hSpCas9	negative selection	12200760
63775554	63775577	15	-	28162770	OCIAML2	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	-0.0015156532075247808	[53]	[298]	0	hSpCas9	negative selection	12200761
63764139	63764162	15	-	28162770	OCIAML2	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-1.7925579201295236	[4]	[7]	-8	hSpCas9	negative selection	12200762
63747055	63747078	15	+	28162770	OCIAML2	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	-0.8135175387651699	[25]	[81]	-5	hSpCas9	negative selection	12200763
63775272	63775295	15	+	28162770	OCIAML3	viability	AAAGTGCATAAAAGACACGCTGG	HERC1	ENSG00000103657	1.481280486980074	[6]	[58]	9	hSpCas9	negative selection	12370121
63727657	63727680	15	-	28162770	OCIAML3	viability	TAGAAGACCAGGAGTTACAGTGG	HERC1	ENSG00000103657	1.2900263416275115	[122]	[907]	9	hSpCas9	negative selection	12370122
63727719	63727742	15	+	28162770	OCIAML3	viability	GAGGTGGCAACAAGTCGAGGAGG	HERC1	ENSG00000103657	0.2856981259581248	[24]	[91]	2	hSpCas9	negative selection	12370123
63716332	63716355	15	-	28162770	OCIAML3	viability	GGAGCCAGAGGATGAAGAGGAGG	HERC1	ENSG00000103657	-5.053439258961461	[10]	[0]	-9	hSpCas9	negative selection	12370124
63636003	63636026	15	-	28162770	OCIAML3	viability	GGAACAGCGACAGGCAGCGGCGG	HERC1	ENSG00000103657	0.5612705851537478	[21]	[97]	5	hSpCas9	negative selection	12370125
63623759	63623782	15	-	28162770	OCIAML3	viability	GAAGGGGCTGATGATGCTGGAGG	HERC1	ENSG00000103657	-0.05069283696149851	[81]	[238]	0	hSpCas9	negative selection	12370126
63775554	63775577	15	-	28162770	OCIAML3	viability	GAACAGCTCCTGGATTACAGAGG	HERC1	ENSG00000103657	1.2581770631942204	[85]	[620]	9	hSpCas9	negative selection	12370127
63764139	63764162	15	-	28162770	OCIAML3	viability	GAACCAACCAGAACATCGGATGG	HERC1	ENSG00000103657	-3.0090451396030073	[7]	[2]	-9	hSpCas9	negative selection	12370128
63747055	63747078	15	+	28162770	OCIAML3	viability	GGCACAGCTTGAGAAAACTGTGG	HERC1	ENSG00000103657	2.684851732671313	[16]	[329]	9	hSpCas9	negative selection	12370129