Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:8924
• Symbol:HERC2
• Description:HECT and RLD domain containing E3 ubiquitin protein ligase 2

DataSource: http://genomecrispr.dkfz.de/#!/results/HERC2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
28263046	28263069	15	-	26472758	Jiyoye	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	-0.38398750704914497	[442]	[255]	-3	hSpCas9	negative selection	70206
28375990	28376013	CHR_HSCHR15_4_CTG8	-	26472758	Jiyoye	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000276802	-0.38398750704914497	[442]	[255]	-3	hSpCas9	negative selection	70207
28393134	28393157	CHR_HSCHR15_4_CTG8	+	26472758	Jiyoye	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000276802	1.2816444994220144	[59]	[109]	7	hSpCas9	negative selection	70208
28280190	28280213	15	+	26472758	Jiyoye	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.2816444994220144	[59]	[109]	7	hSpCas9	negative selection	70209
28369171	28369194	CHR_HSCHR15_4_CTG8	-	26472758	Jiyoye	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000276802	-1.4122523728523058	[119]	[33]	-7	hSpCas9	negative selection	70210
28256227	28256250	15	-	26472758	Jiyoye	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.4122523728523058	[119]	[33]	-7	hSpCas9	negative selection	70211
28359717	28359740	CHR_HSCHR15_4_CTG8	-	26472758	Jiyoye	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000276802	-0.2223057859939273	[180]	[116]	-1	hSpCas9	negative selection	70212
28246772	28246795	15	-	26472758	Jiyoye	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-0.2223057859939273	[180]	[116]	-1	hSpCas9	negative selection	70213
28168513	28168536	15	+	26472758	Jiyoye	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	-0.31864965505513254	[42]	[25]	-2	hSpCas9	negative selection	70214
28167668	28167691	CHR_HSCHR15_4_CTG8	+	26472758	Jiyoye	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000276802	-0.31864965505513254	[42]	[25]	-2	hSpCas9	negative selection	70215
28131376	28131399	CHR_HSCHR15_4_CTG8	+	26472758	Jiyoye	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000276802	0.8099345510062805	[58]	[77]	5	hSpCas9	negative selection	70216
28132222	28132245	15	+	26472758	Jiyoye	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.8099345510062805	[58]	[77]	5	hSpCas9	negative selection	70217
28124065	28124088	15	+	26472758	Jiyoye	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	-0.3714682439102032	[198]	[115]	-3	hSpCas9	negative selection	70218
28123216	28123239	CHR_HSCHR15_4_CTG8	+	26472758	Jiyoye	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000276802	-0.3714682439102032	[198]	[115]	-3	hSpCas9	negative selection	70219
28120501	28120524	CHR_HSCHR15_4_CTG8	+	26472758	Jiyoye	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000276802	0.5335526672754288	[141]	[154]	4	hSpCas9	negative selection	70220
28121349	28121372	15	+	26472758	Jiyoye	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.5335526672754288	[141]	[154]	4	hSpCas9	negative selection	70221
28116750	28116773	15	-	26472758	Jiyoye	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.5756811058628514	[112]	[126]	4	hSpCas9	negative selection	70222
28115929	28115952	CHR_HSCHR15_4_CTG8	-	26472758	Jiyoye	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000276802	0.5756811058628514	[112]	[126]	4	hSpCas9	negative selection	70223
28412338	28412361	CHR_HSCHR15_4_CTG8	-	26472758	Jiyoye	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000276802	-2.6329817449661093	[254]	[30]	-9	hSpCas9	negative selection	70224
28299401	28299424	15	-	26472758	Jiyoye	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-2.6329817449661093	[254]	[30]	-9	hSpCas9	negative selection	70225
28263046	28263069	15	-	26472758	KBM7	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.4014934164956252	[1447,893]	[935,513]	4	hSpCas9	negative selection	261324
28375990	28376013	CHR_HSCHR15_4_CTG8	-	26472758	KBM7	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000276802	0.4014934164956252	[1447,893]	[935,513]	4	hSpCas9	negative selection	261325
28393134	28393157	CHR_HSCHR15_4_CTG8	+	26472758	KBM7	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000276802	0.13210169432748003	[570,558]	[353,236]	1	hSpCas9	negative selection	261326
28280190	28280213	15	+	26472758	KBM7	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.13210169432748003	[570,558]	[353,236]	1	hSpCas9	negative selection	261327
28369171	28369194	CHR_HSCHR15_4_CTG8	-	26472758	KBM7	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000276802	-1.3018215799325659	[813,634]	[172,104]	-7	hSpCas9	negative selection	261328
28256227	28256250	15	-	26472758	KBM7	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.3018215799325659	[813,634]	[172,104]	-7	hSpCas9	negative selection	261329
28359717	28359740	CHR_HSCHR15_4_CTG8	-	26472758	KBM7	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000276802	0.5495889753856351	[849,400]	[392,437]	6	hSpCas9	negative selection	261330
28246772	28246795	15	-	26472758	KBM7	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	0.5495889753856351	[849,400]	[392,437]	6	hSpCas9	negative selection	261331
28168513	28168536	15	+	26472758	KBM7	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	-0.14263404024949589	[223,128]	[73,72]	-1	hSpCas9	negative selection	261332
28167668	28167691	CHR_HSCHR15_4_CTG8	+	26472758	KBM7	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000276802	-0.14263404024949589	[223,128]	[73,72]	-1	hSpCas9	negative selection	261333
28131376	28131399	CHR_HSCHR15_4_CTG8	+	26472758	KBM7	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000276802	0.05817924675096697	[220,296]	[198,66]	0	hSpCas9	negative selection	261334
28132222	28132245	15	+	26472758	KBM7	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.05817924675096697	[220,296]	[198,66]	0	hSpCas9	negative selection	261335
28124065	28124088	15	+	26472758	KBM7	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.06722186702655741	[928,839]	[565,318]	0	hSpCas9	negative selection	261336
28123216	28123239	CHR_HSCHR15_4_CTG8	+	26472758	KBM7	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000276802	0.06722186702655741	[928,839]	[565,318]	0	hSpCas9	negative selection	261337
28120501	28120524	CHR_HSCHR15_4_CTG8	+	26472758	KBM7	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000276802	0.562118006545496	[545,660]	[385,459]	6	hSpCas9	negative selection	261338
28121349	28121372	15	+	26472758	KBM7	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.562118006545496	[545,660]	[385,459]	6	hSpCas9	negative selection	261339
28116750	28116773	15	-	26472758	KBM7	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	-0.14326540402662363	[468,652]	[224,260]	-1	hSpCas9	negative selection	261340
28115929	28115952	CHR_HSCHR15_4_CTG8	-	26472758	KBM7	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000276802	-0.14326540402662363	[468,652]	[224,260]	-1	hSpCas9	negative selection	261341
28412338	28412361	CHR_HSCHR15_4_CTG8	-	26472758	KBM7	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000276802	0.5670085492717769	[410,325]	[218,286]	6	hSpCas9	negative selection	261342
28299401	28299424	15	-	26472758	KBM7	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.5670085492717769	[410,325]	[218,286]	6	hSpCas9	negative selection	261343
28263046	28263069	15	-	26472758	Raji	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	-0.1768248935646044	[603]	[123]	-1	hSpCas9	negative selection	452442
28375990	28376013	CHR_HSCHR15_4_CTG8	-	26472758	Raji	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000276802	-0.1768248935646044	[603]	[123]	-1	hSpCas9	negative selection	452443
28393134	28393157	CHR_HSCHR15_4_CTG8	+	26472758	Raji	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000276802	1.0796918015045511	[262]	[128]	8	hSpCas9	negative selection	452444
28280190	28280213	15	+	26472758	Raji	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.0796918015045511	[262]	[128]	8	hSpCas9	negative selection	452445
28369171	28369194	CHR_HSCHR15_4_CTG8	-	26472758	Raji	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000276802	-1.4565173498197272	[271]	[22]	-7	hSpCas9	negative selection	452446
28256227	28256250	15	-	26472758	Raji	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.4565173498197272	[271]	[22]	-7	hSpCas9	negative selection	452447
28359717	28359740	CHR_HSCHR15_4_CTG8	-	26472758	Raji	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000276802	0.36294282064524663	[257]	[76]	3	hSpCas9	negative selection	452448
28246772	28246795	15	-	26472758	Raji	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	0.36294282064524663	[257]	[76]	3	hSpCas9	negative selection	452449
28168513	28168536	15	+	26472758	Raji	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.37041794120739324	[109]	[32]	3	hSpCas9	negative selection	452450
28167668	28167691	CHR_HSCHR15_4_CTG8	+	26472758	Raji	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000276802	0.37041794120739324	[109]	[32]	3	hSpCas9	negative selection	452451
28131376	28131399	CHR_HSCHR15_4_CTG8	+	26472758	Raji	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000276802	1.7537465807588988	[45]	[35]	9	hSpCas9	negative selection	452452
28132222	28132245	15	+	26472758	Raji	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	1.7537465807588988	[45]	[35]	9	hSpCas9	negative selection	452453
28124065	28124088	15	+	26472758	Raji	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	-0.24418079389001657	[540]	[105]	-2	hSpCas9	negative selection	452454
28123216	28123239	CHR_HSCHR15_4_CTG8	+	26472758	Raji	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000276802	-0.24418079389001657	[540]	[105]	-2	hSpCas9	negative selection	452455
28120501	28120524	CHR_HSCHR15_4_CTG8	+	26472758	Raji	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000276802	0.11173555991330653	[330]	[82]	1	hSpCas9	negative selection	452456
28121349	28121372	15	+	26472758	Raji	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.11173555991330653	[330]	[82]	1	hSpCas9	negative selection	452457
28116750	28116773	15	-	26472758	Raji	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	-0.41427638343903883	[378]	[65]	-3	hSpCas9	negative selection	452458
28115929	28115952	CHR_HSCHR15_4_CTG8	-	26472758	Raji	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000276802	-0.41427638343903883	[378]	[65]	-3	hSpCas9	negative selection	452459
28412338	28412361	CHR_HSCHR15_4_CTG8	-	26472758	Raji	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000276802	0.5746509934250009	[216]	[74]	5	hSpCas9	negative selection	452460
28299401	28299424	15	-	26472758	Raji	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.5746509934250009	[216]	[74]	5	hSpCas9	negative selection	452461
28263046	28263069	15	-	26472758	K562	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.6019263587346342	[792]	[1015]	5	hSpCas9	negative selection	643560
28375990	28376013	CHR_HSCHR15_4_CTG8	-	26472758	K562	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000276802	0.6019263587346342	[792]	[1015]	5	hSpCas9	negative selection	643561
28393134	28393157	CHR_HSCHR15_4_CTG8	+	26472758	K562	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000276802	1.007926109285145	[376]	[639]	8	hSpCas9	negative selection	643562
28280190	28280213	15	+	26472758	K562	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.007926109285145	[376]	[639]	8	hSpCas9	negative selection	643563
28369171	28369194	CHR_HSCHR15_4_CTG8	-	26472758	K562	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000276802	-2.6082601849006473	[678]	[93]	-8	hSpCas9	negative selection	643564
28256227	28256250	15	-	26472758	K562	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-2.6082601849006473	[678]	[93]	-8	hSpCas9	negative selection	643565
28359717	28359740	CHR_HSCHR15_4_CTG8	-	26472758	K562	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000276802	-0.792734270751019	[471]	[229]	-5	hSpCas9	negative selection	643566
28246772	28246795	15	-	26472758	K562	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-0.792734270751019	[471]	[229]	-5	hSpCas9	negative selection	643567
28168513	28168536	15	+	26472758	K562	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.33545380382006984	[260]	[277]	2	hSpCas9	negative selection	643568
28167668	28167691	CHR_HSCHR15_4_CTG8	+	26472758	K562	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000276802	0.33545380382006984	[260]	[277]	2	hSpCas9	negative selection	643569
28131376	28131399	CHR_HSCHR15_4_CTG8	+	26472758	K562	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000276802	0.41530328687003204	[166]	[187]	3	hSpCas9	negative selection	643570
28132222	28132245	15	+	26472758	K562	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.41530328687003204	[166]	[187]	3	hSpCas9	negative selection	643571
28124065	28124088	15	+	26472758	K562	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.2597259804542952	[749]	[757]	2	hSpCas9	negative selection	643572
28123216	28123239	CHR_HSCHR15_4_CTG8	+	26472758	K562	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000276802	0.2597259804542952	[749]	[757]	2	hSpCas9	negative selection	643573
28120501	28120524	CHR_HSCHR15_4_CTG8	+	26472758	K562	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000276802	0.6954989768708219	[503]	[688]	6	hSpCas9	negative selection	643574
28121349	28121372	15	+	26472758	K562	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.6954989768708219	[503]	[688]	6	hSpCas9	negative selection	643575
28116750	28116773	15	-	26472758	K562	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	-1.4845730086277835	[420]	[126]	-6	hSpCas9	negative selection	643576
28115929	28115952	CHR_HSCHR15_4_CTG8	-	26472758	K562	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000276802	-1.4845730086277835	[420]	[126]	-6	hSpCas9	negative selection	643577
28412338	28412361	CHR_HSCHR15_4_CTG8	-	26472758	K562	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000276802	0.33989903652067516	[379]	[405]	2	hSpCas9	negative selection	643578
28299401	28299424	15	-	26472758	K562	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.33989903652067516	[379]	[405]	2	hSpCas9	negative selection	643579
28269285	28269308	15	-	26627737	DLD1	viability	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.011865945689422008	[905]	[233,315,304]	0	hSpCas9	negative selection	790146
28270727	28270750	15	+	26627737	DLD1	viability	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.36412969875145906	[179]	[36,18,69]	-4	hSpCas9	negative selection	790147
28272969	28272992	15	-	26627737	DLD1	viability	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.25477622721000126	[556]	[114,176,146]	-3	hSpCas9	negative selection	790148
28274377	28274400	15	+	26627737	DLD1	viability	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.6758071592765558	[163]	[22,54,20]	-6	hSpCas9	negative selection	790149
28274912	28274935	15	-	26627737	DLD1	viability	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.17876329994498463	[365]	[124,150,38]	-2	hSpCas9	negative selection	790150
28280190	28280213	15	+	26627737	DLD1	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.11038598379736139	[460]	[116,160,124]	-1	hSpCas9	negative selection	790151
28269285	28269308	15	-	26627737	GBM cells	viability after 5 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.5221648603312156	[408]	[236,392]	7	hSpCas9	negative selection	872461
28270727	28270750	15	+	26627737	GBM cells	viability after 5 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.4616464282233763	[108]	[75,84]	7	hSpCas9	negative selection	872462
28272969	28272992	15	-	26627737	GBM cells	viability after 5 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.15348670197128333	[227]	[113,157]	2	hSpCas9	negative selection	872463
28274377	28274400	15	+	26627737	GBM cells	viability after 5 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.36669283623650273	[93]	[60,68]	5	hSpCas9	negative selection	872464
28274912	28274935	15	-	26627737	GBM cells	viability after 5 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.21610405076638473	[121]	[85,65]	3	hSpCas9	negative selection	872465
28280190	28280213	15	+	26627737	GBM cells	viability after 5 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.7398985997797248	[231]	[79,68]	-8	hSpCas9	negative selection	872466
28269285	28269308	15	-	26627737	GBM cells	viability after 13 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.4934510634791843	[408]	[382,254]	6	hSpCas9	negative selection	954776
28270727	28270750	15	+	26627737	GBM cells	viability after 13 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.5696086419660754	[108]	[116,63]	7	hSpCas9	negative selection	954777
28272969	28272992	15	-	26627737	GBM cells	viability after 13 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.0757151683253619	[227]	[123,111]	-1	hSpCas9	negative selection	954778
28274377	28274400	15	+	26627737	GBM cells	viability after 13 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.6028171748044273	[93]	[93,63]	7	hSpCas9	negative selection	954779
28274912	28274935	15	-	26627737	GBM cells	viability after 13 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.32717186074651117	[121]	[103,65]	4	hSpCas9	negative selection	954780
28280190	28280213	15	+	26627737	GBM cells	viability after 13 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.45370023836265205	[231]	[124,64]	-5	hSpCas9	negative selection	954781
28269285	28269308	15	-	26627737	GBM cells	viability after 21 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.5206332314828589	[408]	[335,302]	5	hSpCas9	negative selection	1037091
28270727	28270750	15	+	26627737	GBM cells	viability after 21 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.9978131264798424	[108]	[123,112]	8	hSpCas9	negative selection	1037092
28272969	28272992	15	-	26627737	GBM cells	viability after 21 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.31828932854865233	[227]	[102,95]	-3	hSpCas9	negative selection	1037093
28274377	28274400	15	+	26627737	GBM cells	viability after 21 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.5383434730706249	[93]	[81,66]	5	hSpCas9	negative selection	1037094
28274912	28274935	15	-	26627737	GBM cells	viability after 21 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.8723281015303123	[121]	[136,106]	8	hSpCas9	negative selection	1037095
28280190	28280213	15	+	26627737	GBM cells	viability after 21 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.2016085318632262	[231]	[157,132]	2	hSpCas9	negative selection	1037096
28269285	28269308	15	-	26627737	RPE1	viability after 9 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.5975016888215947	[1056]	[508,489]	4	hSpCas9	negative selection	1119406
28270727	28270750	15	+	26627737	RPE1	viability after 9 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.8605257386529988	[755]	[149,104]	-6	hSpCas9	negative selection	1119407
28272969	28272992	15	-	26627737	RPE1	viability after 9 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.18348475250166502	[1138]	[282,353]	-1	hSpCas9	negative selection	1119408
28274377	28274400	15	+	26627737	RPE1	viability after 9 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	1.4276407904469224	[145]	[163,69]	7	hSpCas9	negative selection	1119409
28274912	28274935	15	-	26627737	RPE1	viability after 9 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.6865074140629968	[462]	[186,292]	4	hSpCas9	negative selection	1119410
28280190	28280213	15	+	26627737	RPE1	viability after 9 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.1175609629466008	[225]	[70,259]	6	hSpCas9	negative selection	1119411
28269285	28269308	15	-	26627737	RPE1	viability after 12 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.5269133488399709	[1056]	[448,366]	3	hSpCas9	negative selection	1201721
28270727	28270750	15	+	26627737	RPE1	viability after 12 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.8014142377003782	[755]	[134,96]	-5	hSpCas9	negative selection	1201722
28272969	28272992	15	-	26627737	RPE1	viability after 12 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.8521775695199489	[1138]	[101,240]	-5	hSpCas9	negative selection	1201723
28274377	28274400	15	+	26627737	RPE1	viability after 12 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.6756939325217475	[145]	[50,74]	4	hSpCas9	negative selection	1201724
28274912	28274935	15	-	26627737	RPE1	viability after 12 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	1.369982059850561	[462]	[321,320]	7	hSpCas9	negative selection	1201725
28280190	28280213	15	+	26627737	RPE1	viability after 12 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.172459372936526	[225]	[131,141]	7	hSpCas9	negative selection	1201726
28269285	28269308	15	-	26627737	RPE1	viability after 15 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.4230731645804717	[1056]	[462,340]	2	hSpCas9	negative selection	1284036
28270727	28270750	15	+	26627737	RPE1	viability after 15 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-1.6202380773413154	[755]	[65,72]	-7	hSpCas9	negative selection	1284037
28272969	28272992	15	-	26627737	RPE1	viability after 15 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-2.2806988168882114	[1138]	[48,82]	-8	hSpCas9	negative selection	1284038
28274377	28274400	15	+	26627737	RPE1	viability after 15 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	1.349213035620426	[145]	[148,62]	7	hSpCas9	negative selection	1284039
28274912	28274935	15	-	26627737	RPE1	viability after 15 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	1.3645986753760382	[462]	[406,269]	7	hSpCas9	negative selection	1284040
28280190	28280213	15	+	26627737	RPE1	viability after 15 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.9291467907831507	[225]	[192,52]	5	hSpCas9	negative selection	1284041
28269285	28269308	15	-	26627737	RPE1	viability after 18 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.4521152382195062	[1056]	[367,413]	3	hSpCas9	negative selection	1366351
28270727	28270750	15	+	26627737	RPE1	viability after 18 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.7234597160889511	[755]	[139,105]	-4	hSpCas9	negative selection	1366352
28272969	28272992	15	-	26627737	RPE1	viability after 18 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.6784939955859216	[1138]	[251,127]	-4	hSpCas9	negative selection	1366353
28274377	28274400	15	+	26627737	RPE1	viability after 18 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.04264512264243381	[145]	[42,37]	0	hSpCas9	negative selection	1366354
28274912	28274935	15	-	26627737	RPE1	viability after 18 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	1.7024915996453087	[462]	[425,385]	8	hSpCas9	negative selection	1366355
28280190	28280213	15	+	26627737	RPE1	viability after 18 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.132002274234408	[225]	[123,143]	6	hSpCas9	negative selection	1366356
28269285	28269308	15	-	26627737	HeLa	viability after 8 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.10016119368762388	[576]	[363,146,313]	1	hSpCas9	negative selection	1448666
28270727	28270750	15	+	26627737	HeLa	viability after 8 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.9733650872130613	[87]	[109,118,8]	7	hSpCas9	negative selection	1448667
28272969	28272992	15	-	26627737	HeLa	viability after 8 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.22839186290737787	[448]	[239,132,144]	-2	hSpCas9	negative selection	1448668
28274377	28274400	15	+	26627737	HeLa	viability after 8 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.9788446310300933	[140]	[182,80,112]	7	hSpCas9	negative selection	1448669
28274912	28274935	15	-	26627737	HeLa	viability after 8 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.2518245887955378	[318]	[267,122,129]	2	hSpCas9	negative selection	1448670
28280190	28280213	15	+	26627737	HeLa	viability after 8 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.12303248441551498	[374]	[205,209,126]	1	hSpCas9	negative selection	1448671
28269285	28269308	15	-	26627737	HeLa	viability after 12 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.15598331022841472	[576]	[142,373,264]	1	hSpCas9	negative selection	1530981
28270727	28270750	15	+	26627737	HeLa	viability after 12 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	1.1241479108991812	[87]	[127,71,39]	7	hSpCas9	negative selection	1530982
28272969	28272992	15	-	26627737	HeLa	viability after 12 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.3769816487845852	[448]	[176,297,239]	3	hSpCas9	negative selection	1530983
28274377	28274400	15	+	26627737	HeLa	viability after 12 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.09984599627495427	[140]	[15,44,101]	-1	hSpCas9	negative selection	1530984
28274912	28274935	15	-	26627737	HeLa	viability after 12 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.6004100449988188	[318]	[236,215,145]	5	hSpCas9	negative selection	1530985
28280190	28280213	15	+	26627737	HeLa	viability after 12 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.06671636622580153	[374]	[71,97,276]	0	hSpCas9	negative selection	1530986
28269285	28269308	15	-	26627737	HeLa	viability after 15 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.30963499240310643	[576]	[248,320,304]	2	hSpCas9	negative selection	1613296
28270727	28270750	15	+	26627737	HeLa	viability after 15 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	1.2646004422176371	[87]	[63,186,0]	8	hSpCas9	negative selection	1613297
28272969	28272992	15	-	26627737	HeLa	viability after 15 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.5503162211244597	[448]	[320,84,406]	4	hSpCas9	negative selection	1613298
28274377	28274400	15	+	26627737	HeLa	viability after 15 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	1.4638539912749202	[140]	[158,36,288]	8	hSpCas9	negative selection	1613299
28274912	28274935	15	-	26627737	HeLa	viability after 15 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.46127797816599037	[318]	[43,164,72]	-4	hSpCas9	negative selection	1613300
28280190	28280213	15	+	26627737	HeLa	viability after 15 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.35243376717997627	[374]	[142,215,228]	3	hSpCas9	negative selection	1613301
28269285	28269308	15	-	26627737	HeLa	viability after 18 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.33411762627955055	[576]	[174,267,304]	3	hSpCas9	negative selection	1695611
28270727	28270750	15	+	26627737	HeLa	viability after 18 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	1.2453905962522394	[87]	[38,156,0]	8	hSpCas9	negative selection	1695612
28272969	28272992	15	-	26627737	HeLa	viability after 18 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.536153500249542	[448]	[212,66,406]	4	hSpCas9	negative selection	1695613
28274377	28274400	15	+	26627737	HeLa	viability after 18 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	1.4591930935655137	[140]	[102,33,288]	8	hSpCas9	negative selection	1695614
28274912	28274935	15	-	26627737	HeLa	viability after 18 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.4804483380928709	[318]	[29,132,72]	-4	hSpCas9	negative selection	1695615
28280190	28280213	15	+	26627737	HeLa	viability after 18 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.3423863293576793	[374]	[89,182,228]	3	hSpCas9	negative selection	1695616
28269285	28269308	15	-	26627737	HCT116	viability after 6 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	-0.3020022838598848	[868]	[182,70]	-2	hSpCas9	negative selection	1777926
28270727	28270750	15	+	26627737	HCT116	viability after 6 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-2.8584167487693732	[405]	[2,11]	-9	hSpCas9	negative selection	1777927
28272969	28272992	15	-	26627737	HCT116	viability after 6 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	1.2959352197957803	[528]	[238,184]	7	hSpCas9	negative selection	1777928
28274377	28274400	15	+	26627737	HCT116	viability after 6 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.8512923143359916	[201]	[5,23]	-5	hSpCas9	negative selection	1777929
28274912	28274935	15	-	26627737	HCT116	viability after 6 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.9239375894131943	[380]	[141,97]	5	hSpCas9	negative selection	1777930
28280190	28280213	15	+	26627737	HCT116	viability after 6 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.5090785624229758	[911]	[170,61]	-3	hSpCas9	negative selection	1777931
28269285	28269308	15	-	26627737	HCT116	viability after 8 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.17046212991683674	[419]	[214,258,305]	2	hSpCas9	negative selection	1860241
28270727	28270750	15	+	26627737	HCT116	viability after 8 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.6575359647653007	[90]	[96,93,46]	6	hSpCas9	negative selection	1860242
28272969	28272992	15	-	26627737	HCT116	viability after 8 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.7764114040643848	[130]	[71,173,123]	7	hSpCas9	negative selection	1860243
28274377	28274400	15	+	26627737	HCT116	viability after 8 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	1.0577837684287976	[110]	[143,87,149]	8	hSpCas9	negative selection	1860244
28274912	28274935	15	-	26627737	HCT116	viability after 8 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.2192118154095202	[335]	[162,137,175]	-3	hSpCas9	negative selection	1860245
28280190	28280213	15	+	26627737	HCT116	viability after 8 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.7220589995689901	[231]	[212,236,182]	7	hSpCas9	negative selection	1860246
28269285	28269308	15	-	26627737	HCT116	viability after 9 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	-0.04976560887482406	[868]	[150,281]	0	hSpCas9	negative selection	1942556
28270727	28270750	15	+	26627737	HCT116	viability after 9 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-1.4689575919037283	[405]	[8,62]	-7	hSpCas9	negative selection	1942557
28272969	28272992	15	-	26627737	HCT116	viability after 9 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.995018602213511	[528]	[409,179]	7	hSpCas9	negative selection	1942558
28274377	28274400	15	+	26627737	HCT116	viability after 9 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.6448855928982715	[201]	[24,41]	-4	hSpCas9	negative selection	1942559
28274912	28274935	15	-	26627737	HCT116	viability after 9 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.6557867412280527	[380]	[252,86]	5	hSpCas9	negative selection	1942560
28280190	28280213	15	+	26627737	HCT116	viability after 9 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.3668961435082006	[911]	[218,164]	-3	hSpCas9	negative selection	1942561
28269285	28269308	15	-	26627737	HCT116	viability after 12 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.4684960859567665	[419]	[250,181,484]	4	hSpCas9	negative selection	2024871
28270727	28270750	15	+	26627737	HCT116	viability after 12 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.5731929468541928	[90]	[57,45,109]	5	hSpCas9	negative selection	2024872
28272969	28272992	15	-	26627737	HCT116	viability after 12 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.7626804273666046	[130]	[99,38,210]	6	hSpCas9	negative selection	2024873
28274377	28274400	15	+	26627737	HCT116	viability after 12 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.1622697397800701	[110]	[36,63,56]	-2	hSpCas9	negative selection	2024874
28274912	28274935	15	-	26627737	HCT116	viability after 12 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.5077453373543646	[335]	[105,75,190]	-5	hSpCas9	negative selection	2024875
28280190	28280213	15	+	26627737	HCT116	viability after 12 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.47166110318129484	[231]	[110,114,284]	4	hSpCas9	negative selection	2024876
28269285	28269308	15	-	26627737	HCT116	viability after 15 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.25216210504727565	[419]	[302,212,346]	2	hSpCas9	negative selection	2107186
28270727	28270750	15	+	26627737	HCT116	viability after 15 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	1.0688104373322012	[90]	[50,98,170]	8	hSpCas9	negative selection	2107187
28272969	28272992	15	-	26627737	HCT116	viability after 15 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.6106185133887079	[130]	[117,111,114]	5	hSpCas9	negative selection	2107188
28274377	28274400	15	+	26627737	HCT116	viability after 15 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.3973695898866414	[110]	[25,148,69]	4	hSpCas9	negative selection	2107189
28274912	28274935	15	-	26627737	HCT116	viability after 15 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.3746751640289149	[335]	[210,172,70]	-4	hSpCas9	negative selection	2107190
28280190	28280213	15	+	26627737	HCT116	viability after 15 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.32746848649297733	[231]	[48,107,153]	-3	hSpCas9	negative selection	2107191
28269285	28269308	15	-	26627737	HCT116	viability after 18 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.09911782854919704	[419]	[228,173,253]	0	hSpCas9	negative selection	2189501
28270727	28270750	15	+	26627737	HCT116	viability after 18 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	1.128084292088023	[90]	[55,90,143]	8	hSpCas9	negative selection	2189502
28272969	28272992	15	-	26627737	HCT116	viability after 18 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.2133009166746771	[130]	[45,86,86]	2	hSpCas9	negative selection	2189503
28274377	28274400	15	+	26627737	HCT116	viability after 18 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.14707536600552995	[110]	[9,58,76]	-1	hSpCas9	negative selection	2189504
28274912	28274935	15	-	26627737	HCT116	viability after 18 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.5318367912415974	[335]	[99,117,118]	-5	hSpCas9	negative selection	2189505
28280190	28280213	15	+	26627737	HCT116	viability after 18 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.15416880455416132	[231]	[57,95,226]	1	hSpCas9	negative selection	2189506
28280168	28280191	15	-	24336569	HL60	viability	CAAGCAGAGGCTGGTGATCTTGG	HERC2	ENSG00000128731	0.3764015838039825	[418]	[1150]	3	hSpCas9	negative selection	2269394
28280177	28280200	15	-	24336569	HL60	viability	CCTGCGACTCAAGCAGAGGCTGG	HERC2	ENSG00000128731	0.23089384280769465	[483]	[1201]	2	hSpCas9	negative selection	2269395
28280186	28280209	15	+	24336569	HL60	viability	GCTTGAGTCGCAGGGCTGAGAGG	HERC2	ENSG00000128731	-0.28385349731772014	[381]	[663]	-2	hSpCas9	negative selection	2269396
28280193	28280216	15	+	24336569	HL60	viability	TCGCAGGGCTGAGAGGGTGGTGG	HERC2	ENSG00000128731	1.6559988888330104	[144]	[966]	9	hSpCas9	negative selection	2269397
28280204	28280227	15	+	24336569	HL60	viability	AGAGGGTGGTGGTGGCTGACTGG	HERC2	ENSG00000128731	0.12788902563639393	[777]	[1798]	1	hSpCas9	negative selection	2269398
28280213	28280236	15	+	24336569	HL60	viability	TGGTGGCTGACTGGACGGCCAGG	HERC2	ENSG00000128731	1.4005768182162743	[258]	[1446]	8	hSpCas9	negative selection	2269399
28280231	28280254	15	-	24336569	HL60	viability	GGTTAAAGAGCAGCAGGCCCTGG	HERC2	ENSG00000128731	0.37375914690012774	[592]	[1625]	3	hSpCas9	negative selection	2269400
28280237	28280260	15	-	24336569	HL60	viability	TGTGCTGGTTAAAGAGCAGCAGG	HERC2	ENSG00000128731	0.005044892625778563	[711]	[1511]	0	hSpCas9	negative selection	2269401
28280252	28280275	15	-	24336569	HL60	viability	GAAGGAGTGTCTTTCTGTGCTGG	HERC2	ENSG00000128731	0.8247315312469377	[968]	[3631]	6	hSpCas9	negative selection	2269402
28299408	28299431	15	+	24336569	HL60	viability	TAGGAGGGAGCTCTCCGTTCTGG	HERC2	ENSG00000128731	-0.0034615886276230245	[125]	[265]	0	hSpCas9	negative selection	2269403
28280168	28280191	15	-	24336569	KBM7	viability	CAAGCAGAGGCTGGTGATCTTGG	HERC2	ENSG00000128731	0.3727147812162197	[332]	[1175]	3	hSpCas9	negative selection	2336571
28280177	28280200	15	-	24336569	KBM7	viability	CCTGCGACTCAAGCAGAGGCTGG	HERC2	ENSG00000128731	0.23254053721261383	[351]	[1127]	2	hSpCas9	negative selection	2336572
28280186	28280209	15	+	24336569	KBM7	viability	GCTTGAGTCGCAGGGCTGAGAGG	HERC2	ENSG00000128731	0.8706918747303908	[236]	[1181]	7	hSpCas9	negative selection	2336573
28280193	28280216	15	+	24336569	KBM7	viability	TCGCAGGGCTGAGAGGGTGGTGG	HERC2	ENSG00000128731	-0.3386448249957186	[152]	[329]	-3	hSpCas9	negative selection	2336574
28280204	28280227	15	+	24336569	KBM7	viability	AGAGGGTGGTGGTGGCTGACTGG	HERC2	ENSG00000128731	-0.31633466327062987	[1049]	[2299]	-3	hSpCas9	negative selection	2336575
28280213	28280236	15	+	24336569	KBM7	viability	TGGTGGCTGACTGGACGGCCAGG	HERC2	ENSG00000128731	1.975455883554166	[207]	[2230]	9	hSpCas9	negative selection	2336576
28280231	28280254	15	-	24336569	KBM7	viability	GGTTAAAGAGCAGCAGGCCCTGG	HERC2	ENSG00000128731	0.6953147072569277	[424]	[1876]	6	hSpCas9	negative selection	2336577
28280237	28280260	15	-	24336569	KBM7	viability	TGTGCTGGTTAAAGAGCAGCAGG	HERC2	ENSG00000128731	0.8984345168627927	[593]	[3019]	7	hSpCas9	negative selection	2336578
28280252	28280275	15	-	24336569	KBM7	viability	GAAGGAGTGTCTTTCTGTGCTGG	HERC2	ENSG00000128731	0.21919065058829612	[856]	[2720]	2	hSpCas9	negative selection	2336579
28299408	28299431	15	+	24336569	KBM7	viability	TAGGAGGGAGCTCTCCGTTCTGG	HERC2	ENSG00000128731	2.5821681468451696	[41]	[685]	9	hSpCas9	negative selection	2336580
28232366	28232389	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTTGTATTTTAGTAGAGACGGAG	HERC2	ENSG00000128731	3.172977660691175	[5,24]	[15,48]	8	dCas9-VP64	positive selection	2389967
28190118	28190141	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACTTGGGAGGCTGAGGCGGG	HERC2	ENSG00000128731	-0.3390870473927914	[36,5]	[4,0]	-1	dCas9-VP64	positive selection	2411798
28189272	28189295	CHR_HSCHR15_4_CTG8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACTTGGGAGGCTGAGGCGGG	HERC2	ENSG00000276802	-0.3390870473927914	[36,5]	[4,0]	-1	dCas9-VP64	positive selection	2411799
28140797	28140820	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCGCACCGGG	HERC2	ENSG00000128731	-0.89146844564302	[3,30]	[1,1]	-5	dCas9-VP64	positive selection	2429466
28139952	28139975	CHR_HSCHR15_4_CTG8	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGAGCCACCGCACCGGG	HERC2	ENSG00000276802	-0.89146844564302	[3,30]	[1,1]	-5	dCas9-VP64	positive selection	2429467
28304948	28304971	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTGAGAATATGCGGTGTTCGG	HERC2	ENSG00000128731	-0.6843799399670565	[176,164]	[29,15]	-3	dCas9-VP64	positive selection	2432574
28417884	28417907	CHR_HSCHR15_4_CTG8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTGAGAATATGCGGTGTTCGG	HERC2	ENSG00000276802	-0.6843799399670565	[176,164]	[29,15]	-3	dCas9-VP64	positive selection	2432575
28369729	28369752	CHR_HSCHR15_4_CTG8	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCATGTTAGCCGGG	HERC2	ENSG00000276802	-0.6909980618209312	[118,65]	[15,7]	-4	dCas9-VP64	positive selection	2439232
28256785	28256808	15	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCATGTTAGCCGGG	HERC2	ENSG00000128731	-0.6909980618209312	[118,65]	[15,7]	-4	dCas9-VP64	positive selection	2439233
28276705	28276728	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTTTGTCGCCCAGGCCAG	HERC2	ENSG00000128731	0.5562418076151273	[52,98]	[38,8]	2	dCas9-VP64	positive selection	2475458
28389648	28389671	CHR_HSCHR15_4_CTG8	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCGCTTTGTCGCCCAGGCCAG	HERC2	ENSG00000276802	0.5562418076151273	[52,98]	[38,8]	2	dCas9-VP64	positive selection	2475460
28424166	28424189	CHR_HSCHR15_4_CTG8	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGCAGTCTGCCCACCTCGG	HERC2	ENSG00000276802	0.20576949065447114	[17,35]	[6,5]	1	dCas9-VP64	positive selection	2476362
28311229	28311252	15	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAAGCAGTCTGCCCACCTCGG	HERC2	ENSG00000128731	0.20576949065447114	[17,35]	[6,5]	1	dCas9-VP64	positive selection	2476363
28232366	28232389	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTTGTATTTTAGTAGAGACGGAG	HERC2	ENSG00000128731	0.6298554829582325	[47,33]	[33,7]	4	dCas9-VP64	positive selection	2485222
28190118	28190141	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACTTGGGAGGCTGAGGCGGG	HERC2	ENSG00000128731	0.46536086309934765	[31,100]	[53,5]	3	dCas9-VP64	positive selection	2507053
28189272	28189295	CHR_HSCHR15_4_CTG8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACTTGGGAGGCTGAGGCGGG	HERC2	ENSG00000276802	0.46536086309934765	[31,100]	[53,5]	3	dCas9-VP64	positive selection	2507054
28140797	28140820	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCGCACCGGG	HERC2	ENSG00000128731	0.12972035773098467	[57,36]	[16,15]	1	dCas9-VP64	positive selection	2524721
28139952	28139975	CHR_HSCHR15_4_CTG8	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGAGCCACCGCACCGGG	HERC2	ENSG00000276802	0.12972035773098467	[57,36]	[16,15]	1	dCas9-VP64	positive selection	2524722
28304948	28304971	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTGAGAATATGCGGTGTTCGG	HERC2	ENSG00000128731	1.7345023813454719	[65,109]	[27,158]	8	dCas9-VP64	positive selection	2527829
28417884	28417907	CHR_HSCHR15_4_CTG8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTGAGAATATGCGGTGTTCGG	HERC2	ENSG00000276802	1.7345023813454719	[65,109]	[27,158]	8	dCas9-VP64	positive selection	2527830
28369729	28369752	CHR_HSCHR15_4_CTG8	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCATGTTAGCCGGG	HERC2	ENSG00000276802	0.84274483203793	[27,27]	[10,20]	5	dCas9-VP64	positive selection	2534487
28256785	28256808	15	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCATGTTAGCCGGG	HERC2	ENSG00000128731	0.84274483203793	[27,27]	[10,20]	5	dCas9-VP64	positive selection	2534488
28276705	28276728	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTTTGTCGCCCAGGCCAG	HERC2	ENSG00000128731	0.09685158778946554	[90,96]	[33,31]	0	dCas9-VP64	positive selection	2570713
28389648	28389671	CHR_HSCHR15_4_CTG8	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCGCTTTGTCGCCCAGGCCAG	HERC2	ENSG00000276802	0.09685158778946554	[90,96]	[33,31]	0	dCas9-VP64	positive selection	2570715
28424166	28424189	CHR_HSCHR15_4_CTG8	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGCAGTCTGCCCACCTCGG	HERC2	ENSG00000276802	0.6530020702020014	[53,174]	[34,79]	5	dCas9-VP64	positive selection	2571617
28311229	28311252	15	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAAGCAGTCTGCCCACCTCGG	HERC2	ENSG00000128731	0.6530020702020014	[53,174]	[34,79]	5	dCas9-VP64	positive selection	2571618
28280204	28280227	15	+	27260157	DLD1	viability	AGAGGGTGGTGGTGGCTGACTGG	HERC2	ENSG00000128731	-0.482035075819516	[]	[]	-4	hSpCas9	negative selection	2575965
28274985	28275008	15	-	27260157	DLD1	viability	AGTTCCCGGCCTGCGGGCAAAGG	HERC2	ENSG00000128731	0.295444141430978	[]	[]	4	hSpCas9	negative selection	2578375
28274376	28274399	15	+	27260157	DLD1	viability	AGGCCTCGGGAAGTGCTCGCAGG	HERC2	ENSG00000128731	0.42667889258833	[]	[]	7	hSpCas9	negative selection	2582579
28280237	28280260	15	-	27260157	DLD1	viability	TGTGCTGGTTAAAGAGCAGCAGG	HERC2	ENSG00000128731	0.192291045000271	[]	[]	3	hSpCas9	negative selection	2582615
28280193	28280216	15	+	27260157	DLD1	viability	TCGCAGGGCTGAGAGGGTGGTGG	HERC2	ENSG00000128731	-2.40775714301036	[]	[]	-9	hSpCas9	negative selection	2587271
28299408	28299431	15	+	27260157	DLD1	viability	TAGGAGGGAGCTCTCCGTTCTGG	HERC2	ENSG00000128731	-0.352959006551691	[]	[]	-3	hSpCas9	negative selection	2606149
28280177	28280200	15	-	27260157	DLD1	viability	CCTGCGACTCAAGCAGAGGCTGG	HERC2	ENSG00000128731	0.0818052766764376	[]	[]	3	hSpCas9	negative selection	2607346
28269339	28269362	15	-	27260157	DLD1	viability	TGCGAAGGCCTGGCCAACCTGGG	HERC2	ENSG00000128731	1.04896120908403	[]	[]	9	hSpCas9	negative selection	2611887
28280187	28280210	15	+	27260157	DLD1	viability	CTTGAGTCGCAGGGCTGAGAGGG	HERC2	ENSG00000128731	-0.553474165100257	[]	[]	-4	hSpCas9	negative selection	2612268
28274976	28274999	15	+	27260157	DLD1	viability	CCCTCCACACCTTTGCCCGCAGG	HERC2	ENSG00000128731	0.839140558336172	[]	[]	9	hSpCas9	negative selection	2613364
28280252	28280275	15	-	27260157	DLD1	viability	GAAGGAGTGTCTTTCTGTGCTGG	HERC2	ENSG00000128731	-0.600218562936812	[]	[]	-5	hSpCas9	negative selection	2614461
28280168	28280191	15	-	27260157	DLD1	viability	CAAGCAGAGGCTGGTGATCTTGG	HERC2	ENSG00000128731	-0.459007509299944	[]	[]	-4	hSpCas9	negative selection	2617467
28280231	28280254	15	-	27260157	DLD1	viability	GGTTAAAGAGCAGCAGGCCCTGG	HERC2	ENSG00000128731	0.11478537430989	[]	[]	3	hSpCas9	negative selection	2618927
28274386	28274409	15	+	27260157	DLD1	viability	AAGTGCTCGCAGGGCGTCCAGGG	HERC2	ENSG00000128731	0.623654121722537	[]	[]	8	hSpCas9	negative selection	2619297
28280186	28280209	15	+	27260157	DLD1	viability	GCTTGAGTCGCAGGGCTGAGAGG	HERC2	ENSG00000128731	0.314239248433835	[]	[]	4	hSpCas9	negative selection	2623613
28280214	28280237	15	+	27260157	DLD1	viability	GGTGGCTGACTGGACGGCCAGGG	HERC2	ENSG00000128731	0.0520470383161438	[]	[]	3	hSpCas9	negative selection	2623948
28274948	28274971	15	+	27260157	DLD1	viability	CGCCGCTCGGGATCCCACTCTGG	HERC2	ENSG00000128731	-1.31046843103915	[]	[]	-7	hSpCas9	negative selection	2644552
28274356	28274379	15	+	27260157	DLD1	viability	GGTGCTCTCGTCAAAGAGCGAGG	HERC2	ENSG00000128731	0.0662546791974983	[]	[]	3	hSpCas9	negative selection	2646305
28280213	28280236	15	+	27260157	DLD1	viability	TGGTGGCTGACTGGACGGCCAGG	HERC2	ENSG00000128731	1.80549199059733	[]	[]	9	hSpCas9	negative selection	2647075
28270727	28270750	15	+	27260157	DLD1	viability	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.257879932656679	[]	[]	4	hSpCas9	negative selection	2648670
28280204	28280227	15	+	27260157	HT1080	viability	AGAGGGTGGTGGTGGCTGACTGG	HERC2	ENSG00000128731	-1.37075538672594	[]	[]	-9	hSpCas9	negative selection	2652095
28274985	28275008	15	-	27260157	HT1080	viability	AGTTCCCGGCCTGCGGGCAAAGG	HERC2	ENSG00000128731	-0.235115817734205	[]	[]	0	hSpCas9	negative selection	2654505
28274376	28274399	15	+	27260157	HT1080	viability	AGGCCTCGGGAAGTGCTCGCAGG	HERC2	ENSG00000128731	0.608013218624094	[]	[]	5	hSpCas9	negative selection	2658709
28280237	28280260	15	-	27260157	HT1080	viability	TGTGCTGGTTAAAGAGCAGCAGG	HERC2	ENSG00000128731	0.910137929796539	[]	[]	7	hSpCas9	negative selection	2658745
28280193	28280216	15	+	27260157	HT1080	viability	TCGCAGGGCTGAGAGGGTGGTGG	HERC2	ENSG00000128731	-3.10462666452842	[]	[]	-9	hSpCas9	negative selection	2663401
28299408	28299431	15	+	27260157	HT1080	viability	TAGGAGGGAGCTCTCCGTTCTGG	HERC2	ENSG00000128731	-0.500530386703267	[]	[]	-7	hSpCas9	negative selection	2682279
28280177	28280200	15	-	27260157	HT1080	viability	CCTGCGACTCAAGCAGAGGCTGG	HERC2	ENSG00000128731	-0.445869710224022	[]	[]	-7	hSpCas9	negative selection	2683476
28269339	28269362	15	-	27260157	HT1080	viability	TGCGAAGGCCTGGCCAACCTGGG	HERC2	ENSG00000128731	0.272474071687585	[]	[]	2	hSpCas9	negative selection	2688017
28280187	28280210	15	+	27260157	HT1080	viability	CTTGAGTCGCAGGGCTGAGAGGG	HERC2	ENSG00000128731	-0.244156413122937	[]	[]	0	hSpCas9	negative selection	2688398
28274976	28274999	15	+	27260157	HT1080	viability	CCCTCCACACCTTTGCCCGCAGG	HERC2	ENSG00000128731	-0.474002528207324	[]	[]	-7	hSpCas9	negative selection	2689494
28280252	28280275	15	-	27260157	HT1080	viability	GAAGGAGTGTCTTTCTGTGCTGG	HERC2	ENSG00000128731	0.191810963874792	[]	[]	1	hSpCas9	negative selection	2690591
28280168	28280191	15	-	27260157	HT1080	viability	CAAGCAGAGGCTGGTGATCTTGG	HERC2	ENSG00000128731	-0.601246666981002	[]	[]	-7	hSpCas9	negative selection	2693597
28280231	28280254	15	-	27260157	HT1080	viability	GGTTAAAGAGCAGCAGGCCCTGG	HERC2	ENSG00000128731	-0.391314589865907	[]	[]	-7	hSpCas9	negative selection	2695057
28274386	28274409	15	+	27260157	HT1080	viability	AAGTGCTCGCAGGGCGTCCAGGG	HERC2	ENSG00000128731	-0.109443774088902	[]	[]	0	hSpCas9	negative selection	2695427
28280186	28280209	15	+	27260157	HT1080	viability	GCTTGAGTCGCAGGGCTGAGAGG	HERC2	ENSG00000128731	-0.751160811314863	[]	[]	-8	hSpCas9	negative selection	2699743
28280214	28280237	15	+	27260157	HT1080	viability	GGTGGCTGACTGGACGGCCAGGG	HERC2	ENSG00000128731	0.759277433098208	[]	[]	6	hSpCas9	negative selection	2700078
28274948	28274971	15	+	27260157	HT1080	viability	CGCCGCTCGGGATCCCACTCTGG	HERC2	ENSG00000128731	-1.13421583122719	[]	[]	-8	hSpCas9	negative selection	2720682
28274356	28274379	15	+	27260157	HT1080	viability	GGTGCTCTCGTCAAAGAGCGAGG	HERC2	ENSG00000128731	-0.143910741887886	[]	[]	0	hSpCas9	negative selection	2722435
28280213	28280236	15	+	27260157	HT1080	viability	TGGTGGCTGACTGGACGGCCAGG	HERC2	ENSG00000128731	1.31796288048744	[]	[]	9	hSpCas9	negative selection	2723205
28270727	28270750	15	+	27260157	HT1080	viability	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.332404908116618	[]	[]	-7	hSpCas9	negative selection	2724800
28280204	28280227	15	+	27260157	MKN45	viability	AGAGGGTGGTGGTGGCTGACTGG	HERC2	ENSG00000128731	-0.517773327357896	[]	[]	-6	hSpCas9	negative selection	2728225
28274985	28275008	15	-	27260157	MKN45	viability	AGTTCCCGGCCTGCGGGCAAAGG	HERC2	ENSG00000128731	0.362949366126351	[]	[]	6	hSpCas9	negative selection	2730635
28274376	28274399	15	+	27260157	MKN45	viability	AGGCCTCGGGAAGTGCTCGCAGG	HERC2	ENSG00000128731	0.867699810865139	[]	[]	8	hSpCas9	negative selection	2734839
28280237	28280260	15	-	27260157	MKN45	viability	TGTGCTGGTTAAAGAGCAGCAGG	HERC2	ENSG00000128731	0.0825410020779466	[]	[]	0	hSpCas9	negative selection	2734875
28280193	28280216	15	+	27260157	MKN45	viability	TCGCAGGGCTGAGAGGGTGGTGG	HERC2	ENSG00000128731	-2.97416268116356	[]	[]	-9	hSpCas9	negative selection	2739531
28299408	28299431	15	+	27260157	MKN45	viability	TAGGAGGGAGCTCTCCGTTCTGG	HERC2	ENSG00000128731	-0.435802502273399	[]	[]	-6	hSpCas9	negative selection	2758409
28280177	28280200	15	-	27260157	MKN45	viability	CCTGCGACTCAAGCAGAGGCTGG	HERC2	ENSG00000128731	-0.218385595109512	[]	[]	-1	hSpCas9	negative selection	2759606
28269339	28269362	15	-	27260157	MKN45	viability	TGCGAAGGCCTGGCCAACCTGGG	HERC2	ENSG00000128731	0.121310011983547	[]	[]	4	hSpCas9	negative selection	2764147
28280187	28280210	15	+	27260157	MKN45	viability	CTTGAGTCGCAGGGCTGAGAGGG	HERC2	ENSG00000128731	-0.491165354758692	[]	[]	-6	hSpCas9	negative selection	2764528
28274976	28274999	15	+	27260157	MKN45	viability	CCCTCCACACCTTTGCCCGCAGG	HERC2	ENSG00000128731	0.15125287284739	[]	[]	5	hSpCas9	negative selection	2765624
28280252	28280275	15	-	27260157	MKN45	viability	GAAGGAGTGTCTTTCTGTGCTGG	HERC2	ENSG00000128731	-0.680284618252906	[]	[]	-7	hSpCas9	negative selection	2766721
28280168	28280191	15	-	27260157	MKN45	viability	CAAGCAGAGGCTGGTGATCTTGG	HERC2	ENSG00000128731	-0.733698964462557	[]	[]	-7	hSpCas9	negative selection	2769727
28280231	28280254	15	-	27260157	MKN45	viability	GGTTAAAGAGCAGCAGGCCCTGG	HERC2	ENSG00000128731	-1.09724741257646	[]	[]	-8	hSpCas9	negative selection	2771187
28274386	28274409	15	+	27260157	MKN45	viability	AAGTGCTCGCAGGGCGTCCAGGG	HERC2	ENSG00000128731	1.3642873908284	[]	[]	9	hSpCas9	negative selection	2771557
28280186	28280209	15	+	27260157	MKN45	viability	GCTTGAGTCGCAGGGCTGAGAGG	HERC2	ENSG00000128731	-0.279408081036294	[]	[]	-1	hSpCas9	negative selection	2775873
28280214	28280237	15	+	27260157	MKN45	viability	GGTGGCTGACTGGACGGCCAGGG	HERC2	ENSG00000128731	0.741740513399765	[]	[]	7	hSpCas9	negative selection	2776208
28274948	28274971	15	+	27260157	MKN45	viability	CGCCGCTCGGGATCCCACTCTGG	HERC2	ENSG00000128731	-1.58111262723711	[]	[]	-9	hSpCas9	negative selection	2796812
28274356	28274379	15	+	27260157	MKN45	viability	GGTGCTCTCGTCAAAGAGCGAGG	HERC2	ENSG00000128731	0.47069453197207	[]	[]	6	hSpCas9	negative selection	2798565
28280213	28280236	15	+	27260157	MKN45	viability	TGGTGGCTGACTGGACGGCCAGG	HERC2	ENSG00000128731	1.25433105224781	[]	[]	9	hSpCas9	negative selection	2799335
28270727	28270750	15	+	27260157	MKN45	viability	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.376916272390643	[]	[]	-1	hSpCas9	negative selection	2800930
28280204	28280227	15	+	27260157	RKO	viability	AGAGGGTGGTGGTGGCTGACTGG	HERC2	ENSG00000128731	-1.22894217922388	[]	[]	-8	hSpCas9	negative selection	2804355
28274985	28275008	15	-	27260157	RKO	viability	AGTTCCCGGCCTGCGGGCAAAGG	HERC2	ENSG00000128731	0.968776914262422	[]	[]	8	hSpCas9	negative selection	2806765
28274376	28274399	15	+	27260157	RKO	viability	AGGCCTCGGGAAGTGCTCGCAGG	HERC2	ENSG00000128731	0.901885212783259	[]	[]	8	hSpCas9	negative selection	2810969
28280237	28280260	15	-	27260157	RKO	viability	TGTGCTGGTTAAAGAGCAGCAGG	HERC2	ENSG00000128731	0.413102760472293	[]	[]	2	hSpCas9	negative selection	2811005
28280193	28280216	15	+	27260157	RKO	viability	TCGCAGGGCTGAGAGGGTGGTGG	HERC2	ENSG00000128731	-3.44978967149202	[]	[]	-9	hSpCas9	negative selection	2815661
28299408	28299431	15	+	27260157	RKO	viability	TAGGAGGGAGCTCTCCGTTCTGG	HERC2	ENSG00000128731	-0.7644545824905	[]	[]	-7	hSpCas9	negative selection	2834539
28280177	28280200	15	-	27260157	RKO	viability	CCTGCGACTCAAGCAGAGGCTGG	HERC2	ENSG00000128731	0.00136685871740869	[]	[]	0	hSpCas9	negative selection	2835736
28269339	28269362	15	-	27260157	RKO	viability	TGCGAAGGCCTGGCCAACCTGGG	HERC2	ENSG00000128731	-0.0457018976453189	[]	[]	0	hSpCas9	negative selection	2840277
28280187	28280210	15	+	27260157	RKO	viability	CTTGAGTCGCAGGGCTGAGAGGG	HERC2	ENSG00000128731	-0.268641852117903	[]	[]	-1	hSpCas9	negative selection	2840658
28274976	28274999	15	+	27260157	RKO	viability	CCCTCCACACCTTTGCCCGCAGG	HERC2	ENSG00000128731	-0.90773853236105	[]	[]	-8	hSpCas9	negative selection	2841754
28280252	28280275	15	-	27260157	RKO	viability	GAAGGAGTGTCTTTCTGTGCTGG	HERC2	ENSG00000128731	0.0693868038672868	[]	[]	0	hSpCas9	negative selection	2842851
28280168	28280191	15	-	27260157	RKO	viability	CAAGCAGAGGCTGGTGATCTTGG	HERC2	ENSG00000128731	-0.601777632787858	[]	[]	-7	hSpCas9	negative selection	2845857
28280231	28280254	15	-	27260157	RKO	viability	GGTTAAAGAGCAGCAGGCCCTGG	HERC2	ENSG00000128731	-0.406784827951661	[]	[]	-6	hSpCas9	negative selection	2847317
28274386	28274409	15	+	27260157	RKO	viability	AAGTGCTCGCAGGGCGTCCAGGG	HERC2	ENSG00000128731	0.527040862921157	[]	[]	3	hSpCas9	negative selection	2847687
28280186	28280209	15	+	27260157	RKO	viability	GCTTGAGTCGCAGGGCTGAGAGG	HERC2	ENSG00000128731	0.289207184583094	[]	[]	1	hSpCas9	negative selection	2852003
28280214	28280237	15	+	27260157	RKO	viability	GGTGGCTGACTGGACGGCCAGGG	HERC2	ENSG00000128731	0.579632203645341	[]	[]	3	hSpCas9	negative selection	2852338
28274948	28274971	15	+	27260157	RKO	viability	CGCCGCTCGGGATCCCACTCTGG	HERC2	ENSG00000128731	-0.372193263075631	[]	[]	-6	hSpCas9	negative selection	2872942
28274356	28274379	15	+	27260157	RKO	viability	GGTGCTCTCGTCAAAGAGCGAGG	HERC2	ENSG00000128731	-0.531466764703746	[]	[]	-6	hSpCas9	negative selection	2874695
28280213	28280236	15	+	27260157	RKO	viability	TGGTGGCTGACTGGACGGCCAGG	HERC2	ENSG00000128731	1.25508850769212	[]	[]	9	hSpCas9	negative selection	2875465
28270727	28270750	15	+	27260157	RKO	viability	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.354774502279901	[]	[]	2	hSpCas9	negative selection	2877060
28280204	28280227	15	+	27260157	SF268	viability	AGAGGGTGGTGGTGGCTGACTGG	HERC2	ENSG00000128731	-0.105004550693859	[]	[]	-1	hSpCas9	negative selection	2880485
28274985	28275008	15	-	27260157	SF268	viability	AGTTCCCGGCCTGCGGGCAAAGG	HERC2	ENSG00000128731	-0.0140131305736738	[]	[]	0	hSpCas9	negative selection	2882895
28274376	28274399	15	+	27260157	SF268	viability	AGGCCTCGGGAAGTGCTCGCAGG	HERC2	ENSG00000128731	0.41480376914137	[]	[]	4	hSpCas9	negative selection	2887099
28280237	28280260	15	-	27260157	SF268	viability	TGTGCTGGTTAAAGAGCAGCAGG	HERC2	ENSG00000128731	0.667986833886233	[]	[]	8	hSpCas9	negative selection	2887135
28280193	28280216	15	+	27260157	SF268	viability	TCGCAGGGCTGAGAGGGTGGTGG	HERC2	ENSG00000128731	-3.08929077869385	[]	[]	-9	hSpCas9	negative selection	2891791
28299408	28299431	15	+	27260157	SF268	viability	TAGGAGGGAGCTCTCCGTTCTGG	HERC2	ENSG00000128731	-1.04110691974591	[]	[]	-7	hSpCas9	negative selection	2910669
28280177	28280200	15	-	27260157	SF268	viability	CCTGCGACTCAAGCAGAGGCTGG	HERC2	ENSG00000128731	0.137474953179703	[]	[]	0	hSpCas9	negative selection	2911866
28269339	28269362	15	-	27260157	SF268	viability	TGCGAAGGCCTGGCCAACCTGGG	HERC2	ENSG00000128731	1.04042210147235	[]	[]	9	hSpCas9	negative selection	2916407
28280187	28280210	15	+	27260157	SF268	viability	CTTGAGTCGCAGGGCTGAGAGGG	HERC2	ENSG00000128731	-0.612267932312184	[]	[]	-5	hSpCas9	negative selection	2916788
28274976	28274999	15	+	27260157	SF268	viability	CCCTCCACACCTTTGCCCGCAGG	HERC2	ENSG00000128731	-0.501114958585298	[]	[]	-4	hSpCas9	negative selection	2917884
28280252	28280275	15	-	27260157	SF268	viability	GAAGGAGTGTCTTTCTGTGCTGG	HERC2	ENSG00000128731	-0.547977868888869	[]	[]	-4	hSpCas9	negative selection	2918981
28280168	28280191	15	-	27260157	SF268	viability	CAAGCAGAGGCTGGTGATCTTGG	HERC2	ENSG00000128731	-0.00833608855592215	[]	[]	0	hSpCas9	negative selection	2921987
28280231	28280254	15	-	27260157	SF268	viability	GGTTAAAGAGCAGCAGGCCCTGG	HERC2	ENSG00000128731	-0.409269993509857	[]	[]	-3	hSpCas9	negative selection	2923447
28274386	28274409	15	+	27260157	SF268	viability	AAGTGCTCGCAGGGCGTCCAGGG	HERC2	ENSG00000128731	0.00282870904378685	[]	[]	0	hSpCas9	negative selection	2923817
28280186	28280209	15	+	27260157	SF268	viability	GCTTGAGTCGCAGGGCTGAGAGG	HERC2	ENSG00000128731	-0.204751755179794	[]	[]	-2	hSpCas9	negative selection	2928133
28280214	28280237	15	+	27260157	SF268	viability	GGTGGCTGACTGGACGGCCAGGG	HERC2	ENSG00000128731	0.775584707677706	[]	[]	8	hSpCas9	negative selection	2928468
28274948	28274971	15	+	27260157	SF268	viability	CGCCGCTCGGGATCCCACTCTGG	HERC2	ENSG00000128731	-1.63749192661925	[]	[]	-8	hSpCas9	negative selection	2949072
28274356	28274379	15	+	27260157	SF268	viability	GGTGCTCTCGTCAAAGAGCGAGG	HERC2	ENSG00000128731	-0.395614994596675	[]	[]	-3	hSpCas9	negative selection	2950825
28280213	28280236	15	+	27260157	SF268	viability	TGGTGGCTGACTGGACGGCCAGG	HERC2	ENSG00000128731	1.67063653966289	[]	[]	9	hSpCas9	negative selection	2951595
28270727	28270750	15	+	27260157	SF268	viability	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.357674585235926	[]	[]	-3	hSpCas9	negative selection	2953190
28234216	28234239	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATCCACTACAGCTACAACGAGG	HERC2	ENSG00000128731	0.2034928791604087	[3,3]	[3,3]	4	hSpCas9	positive selection	2993058
28270703	28270726	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATGTCGGAGAGCTACACAGCGG	HERC2	ENSG00000128731	-1.279975140667617	[3,3]	[1,0]	-9	hSpCas9	positive selection	2993059
28255914	28255937	15	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTTGATGGCTGATGGAGGG	HERC2	ENSG00000128731	-0.7445986372719606	[3,3]	[2,0]	-8	hSpCas9	positive selection	2993060
28245921	28245944	15	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCCTTTCCTGGTGCCAGATGG	HERC2	ENSG00000128731	-0.3007039384959506	[3,3]	[3,0]	-4	hSpCas9	positive selection	2993061
28234216	28234239	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATCCACTACAGCTACAACGAGG	HERC2	ENSG00000128731	-0.3024437891289332	[3,3]	[2,0]	-4	hSpCas9	positive selection	3060916
28270703	28270726	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATGTCGGAGAGCTACACAGCGG	HERC2	ENSG00000128731	-0.6519701055232259	[3,3]	[1,0]	-8	hSpCas9	positive selection	3060917
28255914	28255937	15	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTTGATGGCTGATGGAGGG	HERC2	ENSG00000128731	0.18772850256432305	[3,3]	[1,3]	3	hSpCas9	positive selection	3060918
28245921	28245944	15	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCCTTTCCTGGTGCCAGATGG	HERC2	ENSG00000128731	-0.161924972836023	[3,3]	[3,0]	-2	hSpCas9	positive selection	3060919
28299401	28299424	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	2.8650087886670748	[20,20]	[0,0]	8	hSpCas9	positive selection	3353251
28321409	28321432	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCTCTGAATCTTTCTGTTTGG	HERC2	ENSG00000128731	0.11216826473971475	[148,133]	[0,0]	0	hSpCas9	positive selection	3353252
28321380	28321403	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGGCTCGCCTCGACTCCAAATGG	HERC2	ENSG00000128731	1.212789229776933	[66,64]	[0,0]	5	hSpCas9	positive selection	3353253
28299497	28299520	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAGCTTGCATTCACAAGAGATGG	HERC2	ENSG00000128731	0.6426163673306269	[97,97]	[0,0]	3	hSpCas9	positive selection	3372445
28293001	28293024	15	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATGATAGTGTCGAACCAAGTGG	HERC2	ENSG00000128731	1.0675016525658179	[72,72]	[0,0]	5	hSpCas9	positive selection	3372446
28292907	28292930	15	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGCTGTCCAGAATTGACTTGG	HERC2	ENSG00000128731	-1.1563017175783374	[340,340]	[0,0]	-7	hSpCas9	positive selection	3372447
28234216	28234239	15	-	26780180	HT29	viability (Avana library 4 designs)	GATCCACTACAGCTACAACGAGG	HERC2	ENSG00000128731	2.67496184883697	[]	[]	8	hSpCas9	negative selection	3430319
28270702	28270725	15	+	26780180	HT29	viability (Avana library 4 designs)	GATGTCGGAGAGCTACACAGCGG	HERC2	ENSG00000128731	2.80670699235362	[]	[]	8	hSpCas9	negative selection	3430320
28255914	28255937	15	-	26780180	HT29	viability (Avana library 4 designs)	GCAGCTTGATGGCTGATGGAGGG	HERC2	ENSG00000128731	2.16821746072662	[]	[]	7	hSpCas9	negative selection	3430321
28245920	28245943	15	+	26780180	HT29	viability (Avana library 4 designs)	GTTCCTTTCCTGGTGCCAGATGG	HERC2	ENSG00000128731	0.802550961287634	[]	[]	3	hSpCas9	negative selection	3430322
28270702	28270725	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGTCGGAGAGCTACACAGCGG	HERC2	ENSG00000128731	-0.517450203664236	[]	[]	0	hSpCas9	negative selection	3515421
28255914	28255937	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTTGATGGCTGATGGAGGG	HERC2	ENSG00000128731	-13.5948435604632	[]	[]	-8	hSpCas9	negative selection	3515422
28234216	28234239	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCCACTACAGCTACAACGAGG	HERC2	ENSG00000128731	-16.4883260239422	[]	[]	-9	hSpCas9	negative selection	3515423
28245920	28245943	15	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCTTTCCTGGTGCCAGATGG	HERC2	ENSG00000128731	1.74019822423579	[]	[]	2	hSpCas9	negative selection	3515424
28254402	28254425	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAAAGACCTTATTAATACGGGG	HERC2	ENSG00000128731	-17.5110404363145	[]	[]	-9	hSpCas9	negative selection	3515425
28270772	28270795	15	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATTGATCTGCGACAAACGGCGG	HERC2	ENSG00000128731	-1.03829018917638	[]	[]	-1	hSpCas9	negative selection	3515426
28270702	28270725	15	+	26780180	A375	viability (Avana lentiGuide)	GATGTCGGAGAGCTACACAGCGG	HERC2	ENSG00000128731	9.20928453626572	[]	[]	6	hSpCas9	negative selection	3624080
28255914	28255937	15	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTTGATGGCTGATGGAGGG	HERC2	ENSG00000128731	19.5993393228979	[]	[]	8	hSpCas9	negative selection	3624081
28234216	28234239	15	-	26780180	A375	viability (Avana lentiGuide)	GATCCACTACAGCTACAACGAGG	HERC2	ENSG00000128731	19.7813927146699	[]	[]	8	hSpCas9	negative selection	3624082
28245920	28245943	15	+	26780180	A375	viability (Avana lentiGuide)	GTTCCTTTCCTGGTGCCAGATGG	HERC2	ENSG00000128731	-4.31880099229836	[]	[]	-7	hSpCas9	negative selection	3624083
28254402	28254425	15	-	26780180	A375	viability (Avana lentiGuide)	ATAAAGACCTTATTAATACGGGG	HERC2	ENSG00000128731	19.4511548072384	[]	[]	8	hSpCas9	negative selection	3624084
28270772	28270795	15	-	26780180	A375	viability (Avana lentiGuide)	CATTGATCTGCGACAAACGGCGG	HERC2	ENSG00000128731	0	[]	[]	0	hSpCas9	negative selection	3624085
28270702	28270725	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGTCGGAGAGCTACACAGCGG	HERC2	ENSG00000128731	-0.95633102694006	[4]	[0,2]	-8	hSpCas9	positive selection	3732739
28255914	28255937	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTTGATGGCTGATGGAGGG	HERC2	ENSG00000128731	-0.580364328585942	[5]	[2,4]	-7	hSpCas9	positive selection	3732740
28234216	28234239	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCCACTACAGCTACAACGAGG	HERC2	ENSG00000128731	-1.5413477568385832	[4]	[0,0]	-9	hSpCas9	positive selection	3732741
28245920	28245943	15	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCTTTCCTGGTGCCAGATGG	HERC2	ENSG00000128731	0.36170478513288795	[4]	[6,4]	9	hSpCas9	positive selection	3732742
28254402	28254425	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAAAGACCTTATTAATACGGGG	HERC2	ENSG00000128731	-1.2083043331761325	[10]	[3,4]	-9	hSpCas9	positive selection	3732743
28270772	28270795	15	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTGATCTGCGACAAACGGCGG	HERC2	ENSG00000128731	-0.29217818718030353	[0]	[0,0]	-4	hSpCas9	positive selection	3732744
28270702	28270725	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGTCGGAGAGCTACACAGCGG	HERC2	ENSG00000128731	-0.7536272664203588	[5]	[2,1]	-7	hSpCas9	positive selection	3841346
28255914	28255937	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTTGATGGCTGATGGAGGG	HERC2	ENSG00000128731	-1.155625933261619	[6]	[1,1]	-8	hSpCas9	positive selection	3841347
28234216	28234239	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCCACTACAGCTACAACGAGG	HERC2	ENSG00000128731	-0.9593988906472487	[6]	[3,0]	-8	hSpCas9	positive selection	3841348
28245920	28245943	15	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCTTTCCTGGTGCCAGATGG	HERC2	ENSG00000128731	0.13157622354658477	[5]	[5,3]	3	hSpCas9	positive selection	3841349
28254402	28254425	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAAAGACCTTATTAATACGGGG	HERC2	ENSG00000128731	-0.7395269362825263	[6]	[1,3]	-7	hSpCas9	positive selection	3841350
28270772	28270795	15	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTGATCTGCGACAAACGGCGG	HERC2	ENSG00000128731	0.24644513604583196	[0]	[0,0]	6	hSpCas9	positive selection	3841351
28299401	28299424	15	-	26780180	A375	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.403038616328258	[]	[]	1	hSpCas9	negative selection	3947418
28299401	28299424	15	-	26780180	HT29	viability (GeCKOv2 library)	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.539736991016877	[]	[]	1	hSpCas9	negative selection	4055384
28299401	28299424	15	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.2638764338927275	[0]	[0,0]	-5	hSpCas9	positive selection	4274835
28245872	28245894	15	+	27760321	OCIAML3	viability	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	-0.23790422775733377	[948,814]	[521,662]	-3	hSpCas9	negative selection	4406640
28245935	28245957	15	-	27760321	OCIAML3	viability	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.5580734765487914	[535,447]	[512,630]	6	hSpCas9	negative selection	4406641
28260841	28260863	15	+	27760321	OCIAML3	viability	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	-0.0027207226373587856	[916,798]	[619,730]	0	hSpCas9	negative selection	4406642
28265687	28265709	15	+	27760321	OCIAML3	viability	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.5798766826856121	[777,549]	[657,910]	7	hSpCas9	negative selection	4406643
28274895	28274917	15	+	27760321	OCIAML3	viability	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	-0.8739470244867444	[719,620]	[224,363]	-7	hSpCas9	negative selection	4406644
28245872	28245894	15	+	27760321	OCIAML2	viability	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.040627987680442734	[948,814]	[647,841]	0	hSpCas9	negative selection	4490103
28245935	28245957	15	-	27760321	OCIAML2	viability	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.36430963845016723	[535,447]	[533,478]	5	hSpCas9	negative selection	4490104
28260841	28260863	15	+	27760321	OCIAML2	viability	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.21825676976254527	[916,798]	[704,937]	3	hSpCas9	negative selection	4490105
28265687	28265709	15	+	27760321	OCIAML2	viability	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.4997613028175807	[777,549]	[601,947]	6	hSpCas9	negative selection	4490106
28274895	28274917	15	+	27760321	OCIAML2	viability	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.04637276727144668	[719,620]	[495,640]	0	hSpCas9	negative selection	4490107
28245872	28245894	15	+	27760321	MV411	viability	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	1.4213869682512026	[948,814]	[1953,953]	8	hSpCas9	negative selection	4573566
28245935	28245957	15	-	27760321	MV411	viability	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	-0.015641050388240846	[535,447]	[159,559]	0	hSpCas9	negative selection	4573567
28260841	28260863	15	+	27760321	MV411	viability	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.32546796299987957	[916,798]	[716,693]	2	hSpCas9	negative selection	4573568
28265687	28265709	15	+	27760321	MV411	viability	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	1.0594595526150028	[777,549]	[842,993]	7	hSpCas9	negative selection	4573569
28274895	28274917	15	+	27760321	MV411	viability	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.39775164240665095	[719,620]	[709,387]	3	hSpCas9	negative selection	4573570
28245872	28245894	15	+	27760321	HL60	viability	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.12510817375887529	[948,814]	[830,732]	1	hSpCas9	negative selection	4657029
28245935	28245957	15	-	27760321	HL60	viability	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.5305231948183542	[535,447]	[583,571]	6	hSpCas9	negative selection	4657030
28260841	28260863	15	+	27760321	HL60	viability	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	-0.11852074021413062	[916,798]	[596,693]	-1	hSpCas9	negative selection	4657031
28265687	28265709	15	+	27760321	HL60	viability	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.8093055255443249	[777,549]	[814,1072]	8	hSpCas9	negative selection	4657032
28274895	28274917	15	+	27760321	HL60	viability	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.06617465795460065	[719,620]	[615,524]	0	hSpCas9	negative selection	4657033
28245872	28245894	15	+	27760321	HT1080	viability	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	-0.08081117103981006	[814,635]	[278,266]	0	hSpCas9	negative selection	4740492
28245935	28245957	15	-	27760321	HT1080	viability	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	-1.0552942632553544	[447,349]	[128,18]	-4	hSpCas9	negative selection	4740493
28260841	28260863	15	+	27760321	HT1080	viability	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.08049928021475261	[798,623]	[356,236]	0	hSpCas9	negative selection	4740494
28265687	28265709	15	+	27760321	HT1080	viability	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.6770112700985541	[549,428]	[369,247]	3	hSpCas9	negative selection	4740495
28274895	28274917	15	+	27760321	HT1080	viability	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.296114284677384	[620,484]	[396,131]	1	hSpCas9	negative selection	4740496
28245872	28245894	15	+	27760321	HT29	viability after 7 days	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.45052950053210306	[814,635]	[1409,1363,1073]	7	hSpCas9	negative selection	4823955
28245935	28245957	15	-	27760321	HT29	viability after 7 days	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.17135457699985482	[447,349]	[687,447,610]	2	hSpCas9	negative selection	4823956
28260841	28260863	15	+	27760321	HT29	viability after 7 days	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.21833796109106207	[798,623]	[1256,934,1027]	3	hSpCas9	negative selection	4823957
28265687	28265709	15	+	27760321	HT29	viability after 7 days	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.40252452546478945	[549,428]	[845,773,874]	6	hSpCas9	negative selection	4823958
28274895	28274917	15	+	27760321	HT29	viability after 7 days	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	-0.08175810346000234	[620,484]	[882,721,446]	-1	hSpCas9	negative selection	4823959
28245872	28245894	15	+	27760321	HT29	viability after 25 days	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.6409445625680408	[814,635]	[1369,1034,1486]	7	hSpCas9	negative selection	4907418
28245935	28245957	15	-	27760321	HT29	viability after 25 days	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.3819603088722622	[447,349]	[662,713,377]	4	hSpCas9	negative selection	4907419
28260841	28260863	15	+	27760321	HT29	viability after 25 days	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.32955236495851725	[798,623]	[870,1011,1209]	3	hSpCas9	negative selection	4907420
28265687	28265709	15	+	27760321	HT29	viability after 25 days	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.5175551361835106	[549,428]	[959,682,741]	6	hSpCas9	negative selection	4907421
28274895	28274917	15	+	27760321	HT29	viability after 25 days	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.3501284078526269	[620,484]	[827,695,899]	4	hSpCas9	negative selection	4907422
28245872	28245894	15	+	27760321	HT29	viability after 22 days	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.7561004758231076	[814,635]	[1747,1233,1256]	8	hSpCas9	negative selection	4990881
28245935	28245957	15	-	27760321	HT29	viability after 22 days	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.02191129077067755	[447,349]	[359,575,471]	0	hSpCas9	negative selection	4990882
28260841	28260863	15	+	27760321	HT29	viability after 22 days	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.424279041842448	[798,623]	[968,1136,1209]	4	hSpCas9	negative selection	4990883
28265687	28265709	15	+	27760321	HT29	viability after 22 days	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.8372760434719005	[549,428]	[956,1010,1066]	8	hSpCas9	negative selection	4990884
28274895	28274917	15	+	27760321	HT29	viability after 22 days	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.012808178309249296	[620,484]	[474,572,893]	0	hSpCas9	negative selection	4990885
28245872	28245894	15	+	27760321	HT29	viability after 19 days	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.5163670378458785	[814,635]	[1411,925,1242]	5	hSpCas9	negative selection	5074344
28245935	28245957	15	-	27760321	HT29	viability after 19 days	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.5055538390672568	[447,349]	[484,762,676]	5	hSpCas9	negative selection	5074345
28260841	28260863	15	+	27760321	HT29	viability after 19 days	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.581197661885323	[798,623]	[1077,1074,1473]	6	hSpCas9	negative selection	5074346
28265687	28265709	15	+	27760321	HT29	viability after 19 days	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.7963331501923495	[549,428]	[1273,873,805]	7	hSpCas9	negative selection	5074347
28274895	28274917	15	+	27760321	HT29	viability after 19 days	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.7283459006915917	[620,484]	[889,1420,823]	7	hSpCas9	negative selection	5074348
28245872	28245894	15	+	27760321	HT29	viability after 16 days	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.6208586121785387	[814,635]	[1076,1218,1432]	7	hSpCas9	negative selection	5157807
28245935	28245957	15	-	27760321	HT29	viability after 16 days	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.4491853254181627	[447,349]	[569,634,618]	5	hSpCas9	negative selection	5157808
28260841	28260863	15	+	27760321	HT29	viability after 16 days	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.6450850444982299	[798,623]	[1520,1267,970]	7	hSpCas9	negative selection	5157809
28265687	28265709	15	+	27760321	HT29	viability after 16 days	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.8272503517022792	[549,428]	[975,904,1035]	8	hSpCas9	negative selection	5157810
28274895	28274917	15	+	27760321	HT29	viability after 16 days	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	0.06935132487006979	[620,484]	[795,470,698]	0	hSpCas9	negative selection	5157811
28245872	28245894	15	+	27760321	HT29	viability after 13 days	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.41648405403922917	[814,635]	[959,1164,1237]	5	hSpCas9	negative selection	5241270
28245935	28245957	15	-	27760321	HT29	viability after 13 days	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.22310100907896493	[447,349]	[342,680,593]	2	hSpCas9	negative selection	5241271
28260841	28260863	15	+	27760321	HT29	viability after 13 days	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.577302209021312	[798,623]	[1241,1244,1208]	7	hSpCas9	negative selection	5241272
28265687	28265709	15	+	27760321	HT29	viability after 13 days	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.924756388101258	[549,428]	[1053,1104,1074]	9	hSpCas9	negative selection	5241273
28274895	28274917	15	+	27760321	HT29	viability after 13 days	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	-0.034094586992753806	[620,484]	[396,955,532]	0	hSpCas9	negative selection	5241274
28245872	28245894	15	+	27760321	HT29	viability after 10 days	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.396551589539218	[814,635]	[1308,1060,1202]	5	hSpCas9	negative selection	5324733
28245935	28245957	15	-	27760321	HT29	viability after 10 days	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.1498825276685017	[447,349]	[393,740,528]	2	hSpCas9	negative selection	5324734
28260841	28260863	15	+	27760321	HT29	viability after 10 days	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	0.1482528105115799	[798,623]	[942,1194,824]	2	hSpCas9	negative selection	5324735
28265687	28265709	15	+	27760321	HT29	viability after 10 days	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.7410579818314876	[549,428]	[1189,800,1065]	8	hSpCas9	negative selection	5324736
28274895	28274917	15	+	27760321	HT29	viability after 10 days	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	-0.03424456484465632	[620,484]	[861,815,355]	0	hSpCas9	negative selection	5324737
28245872	28245894	15	+	27760321	MOLM13	viability	ACGCCGTACCCATTATGCCAGG	HERC2	ENSG00000128731	0.9120668168063633	[948,814]	[1516,436]	6	hSpCas9	negative selection	5408196
28245935	28245957	15	-	27760321	MOLM13	viability	CTGGATCGGTTCAACCATCTGG	HERC2	ENSG00000128731	0.7881940795717086	[535,447]	[686,298]	5	hSpCas9	negative selection	5408197
28260841	28260863	15	+	27760321	MOLM13	viability	TCTGGCTTGGTCACGCGCAAGG	HERC2	ENSG00000128731	1.7006479044472562	[916,798]	[1202,1881]	9	hSpCas9	negative selection	5408198
28265687	28265709	15	+	27760321	MOLM13	viability	TAAGCCCGGCTACCAGCATCGG	HERC2	ENSG00000128731	0.1060101617722421	[777,549]	[427,373]	0	hSpCas9	negative selection	5408199
28274895	28274917	15	+	27760321	MOLM13	viability	GGGACCGTACCTGATCGCCAGG	HERC2	ENSG00000128731	-0.1361514314143638	[719,620]	[110,540]	-1	hSpCas9	negative selection	5408200
28299401	28299424	15	-	27260156	BXPC3	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.3820763289530378	[41]	[40,16,58,15]	-7	hSpCas9	negative selection	5547295
28299401	28299424	15	-	27260156	A673	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.1807689147494198	[41]	[44,32,54,96]	4	hSpCas9	negative selection	5668546
28299401	28299424	15	-	27260156	A375	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-1.513463955640538	[41]	[9,33,0,24]	-9	hSpCas9	negative selection	5789797
28299401	28299424	15	-	27260156	COLO741	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.26209851094709524	[41]	[33,36,60]	-5	hSpCas9	negative selection	5911048
28299401	28299424	15	-	27260156	CAL120	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.5725071448289105	[41]	[52,13,40]	-7	hSpCas9	negative selection	6032299
28299401	28299424	15	-	27260156	CADOES1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.18935644890452608	[41]	[39,30,31,33]	-3	hSpCas9	negative selection	6153550
28299401	28299424	15	-	27260156	EWS502	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.04307166701212228	[41]	[49,21,53,46]	-1	hSpCas9	negative selection	6274801
28299401	28299424	15	-	27260156	EW8	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.08933757335959047	[41]	[45,36,10,38]	-2	hSpCas9	negative selection	6396052
28299401	28299424	15	-	27260156	CORL105	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.32185491879794315	[41]	[30,15,61,51]	-5	hSpCas9	negative selection	6517303
28299401	28299424	15	-	27260156	HS294T	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.3354701314819102	[41]	[19,5,11,12]	-5	hSpCas9	negative selection	6638554
28299401	28299424	15	-	27260156	HCC44	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.2588805478237344	[41]	[53,24,70,17]	-4	hSpCas9	negative selection	6759805
28299401	28299424	15	-	27260156	G402	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-1.0023710299332178	[41]	[10,16,53,17]	-8	hSpCas9	negative selection	6881056
28299401	28299424	15	-	27260156	L33	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.6480121078071823	[41]	[22,14,19,15]	-9	hSpCas9	negative selection	7002307
28299401	28299424	15	-	27260156	K562	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-2.072114567684359	[41]	[4,4,16,7]	-9	hSpCas9	negative selection	7123558
28299401	28299424	15	-	27260156	HT29	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.2303767382270201	[41]	[81,87,37,37]	4	hSpCas9	negative selection	7244809
28299401	28299424	15	-	27260156	MHHES1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.9152367927214775	[41]	[148,175,21,35]	9	hSpCas9	negative selection	7366060
28299401	28299424	15	-	27260156	MEWO	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.328896296424495	[41]	[84,40,28]	7	hSpCas9	negative selection	7487311
28299401	28299424	15	-	27260156	LNCAPCLONEFGC	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.05699357111875791	[41]	[5,34,83,28]	-1	hSpCas9	negative selection	7608562
28299401	28299424	15	-	27260156	PANC0327	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.6510043567719093	[41]	[56,13,10,16]	-7	hSpCas9	negative selection	7729813
28299401	28299424	15	-	27260156	NCIH2009	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.11990763609790189	[41]	[46,82,29]	-2	hSpCas9	negative selection	7851064
28299401	28299424	15	-	27260156	NCIH1373	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.08989071811868321	[41]	[29,10,14,39]	0	hSpCas9	negative selection	7972315
28299401	28299424	15	-	27260156	PATU8902	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-1.1876547114128542	[41]	[19,73,6,3]	-8	hSpCas9	negative selection	8093566
28299401	28299424	15	-	27260156	PANC1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.22946169413266748	[41]	[54,51,66,2]	3	hSpCas9	negative selection	8214817
28299401	28299424	15	-	27260156	PANC0813	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.35517786867854495	[41]	[80,33,74,63]	6	hSpCas9	negative selection	8336068
28299401	28299424	15	-	27260156	RDES	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.06960131051063145	[41]	[68,63,36,19]	1	hSpCas9	negative selection	8457319
28299401	28299424	15	-	27260156	PC3	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.5103354482151143	[41]	[102,25,21,39]	9	hSpCas9	negative selection	8578570
28299401	28299424	15	-	27260156	PATU8988T	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	1.332659114856166	[41]	[20,54,260,61]	9	hSpCas9	negative selection	8699821
28299401	28299424	15	-	27260156	T47D	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.25967399096397825	[41]	[59,74,42,54]	5	hSpCas9	negative selection	8821072
28299401	28299424	15	-	27260156	SU8686	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.016296782497213336	[41]	[15,35,34,92]	0	hSpCas9	negative selection	8942323
28299401	28299424	15	-	27260156	SKES1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.09993077198364153	[41]	[80,19,42,37]	2	hSpCas9	negative selection	9063574
28299401	28299424	15	-	27260156	TOV112D	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.43186970039070793	[41]	[21,44,17,41]	-7	hSpCas9	negative selection	9184825
28299401	28299424	15	-	27260156	TC71	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.0008528857980176774	[41]	[40,48,37,52]	0	hSpCas9	negative selection	9306076
28299401	28299424	15	-	27260156	TC32	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.5611641936223415	[41]	[70,19,115,44]	8	hSpCas9	negative selection	9427327
28269285	28269308	15	-	27869803	HPAFII	viability after 27 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	1.5495371625790613	[293]	[452,451,NaN]	9	hSpCas9	negative selection	9553152
28270727	28270750	15	+	27869803	HPAFII	viability after 27 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-1.650495660760213	[75]	[9,14,NaN]	-8	hSpCas9	negative selection	9553153
28272969	28272992	15	-	27869803	HPAFII	viability after 27 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.04805101895694516	[237]	[202,67,NaN]	0	hSpCas9	negative selection	9553154
28274377	28274400	15	+	27869803	HPAFII	viability after 27 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-2.263362328335692	[131]	[26,3,NaN]	-8	hSpCas9	negative selection	9553155
28274912	28274935	15	-	27869803	HPAFII	viability after 27 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-1.2643708533966076	[215]	[61,34,NaN]	-7	hSpCas9	negative selection	9553156
28280190	28280213	15	+	27869803	HPAFII	viability after 27 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.38270772495578437	[201]	[159,15,NaN]	-3	hSpCas9	negative selection	9553157
28269285	28269308	15	-	27869803	HPAFII	viability after 15 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	1.1776892865922317	[293]	[752,690,NaN]	9	hSpCas9	negative selection	9635601
28270727	28270750	15	+	27869803	HPAFII	viability after 15 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.9049792575457802	[75]	[79,20,NaN]	-7	hSpCas9	negative selection	9635602
28272969	28272992	15	-	27869803	HPAFII	viability after 15 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	0.4547185519507373	[237]	[611,187,NaN]	5	hSpCas9	negative selection	9635603
28274377	28274400	15	+	27869803	HPAFII	viability after 15 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.30443071036678604	[131]	[215,51,NaN]	-3	hSpCas9	negative selection	9635604
28274912	28274935	15	-	27869803	HPAFII	viability after 15 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.006078995030330825	[215]	[287,198,NaN]	0	hSpCas9	negative selection	9635605
28280190	28280213	15	+	27869803	HPAFII	viability after 15 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.1937362067106847	[201]	[563,51,NaN]	2	hSpCas9	negative selection	9635606
28269285	28269308	15	-	27869803	ASPC1	viability after 36 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	-0.013487922294833643	[933]	[316,352,299]	0	hSpCas9	negative selection	9718050
28270727	28270750	15	+	27869803	ASPC1	viability after 36 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	0.8855511488963719	[238]	[162,219,93]	8	hSpCas9	negative selection	9718051
28272969	28272992	15	-	27869803	ASPC1	viability after 36 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.6740217580088604	[593]	[160,67,155]	-6	hSpCas9	negative selection	9718052
28274377	28274400	15	+	27869803	ASPC1	viability after 36 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	0.8283849189436756	[241]	[33,310,101]	7	hSpCas9	negative selection	9718053
28274912	28274935	15	-	27869803	ASPC1	viability after 36 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.8067607514332132	[369]	[465,244,39]	7	hSpCas9	negative selection	9718054
28280190	28280213	15	+	27869803	ASPC1	viability after 36 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.6613641173823148	[677]	[201,647,273]	6	hSpCas9	negative selection	9718055
28269285	28269308	15	-	27869803	PATU8988S	viability after 35 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.1579644693735544	[747]	[386,284,NaN]	1	hSpCas9	negative selection	9800499
28270727	28270750	15	+	27869803	PATU8988S	viability after 35 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.38791609714307773	[163]	[40,59,NaN]	-4	hSpCas9	negative selection	9800500
28272969	28272992	15	-	27869803	PATU8988S	viability after 35 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-1.4887888146375727	[665]	[127,62,NaN]	-8	hSpCas9	negative selection	9800501
28274377	28274400	15	+	27869803	PATU8988S	viability after 35 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-1.2950233940899822	[331]	[50,57,NaN]	-8	hSpCas9	negative selection	9800502
28274912	28274935	15	-	27869803	PATU8988S	viability after 35 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-0.18489800279250018	[405]	[76,210,NaN]	-2	hSpCas9	negative selection	9800503
28280190	28280213	15	+	27869803	PATU8988S	viability after 35 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.7275853832387011	[482]	[107,126,NaN]	-6	hSpCas9	negative selection	9800504
28269285	28269308	15	-	27869803	PATU8988S	viability after 31 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	0.4866813984712987	[747]	[453,371,NaN]	6	hSpCas9	negative selection	9882948
28270727	28270750	15	+	27869803	PATU8988S	viability after 31 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-0.3273773811930769	[163]	[41,64,NaN]	-4	hSpCas9	negative selection	9882949
28272969	28272992	15	-	27869803	PATU8988S	viability after 31 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-1.5934052085059685	[665]	[109,59,NaN]	-8	hSpCas9	negative selection	9882950
28274377	28274400	15	+	27869803	PATU8988S	viability after 31 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-0.5651403112556257	[331]	[70,112,NaN]	-6	hSpCas9	negative selection	9882951
28274912	28274935	15	-	27869803	PATU8988S	viability after 31 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	0.31869480612167733	[405]	[149,267,NaN]	4	hSpCas9	negative selection	9882952
28280190	28280213	15	+	27869803	PATU8988S	viability after 31 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.47105961908856053	[482]	[57,241,NaN]	-5	hSpCas9	negative selection	9882953
28269285	28269308	15	-	27869803	HPAFII	viability after 35 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	1.7668290377777716	[293]	[442,577,NaN]	9	hSpCas9	negative selection	9965397
28270727	28270750	15	+	27869803	HPAFII	viability after 35 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-1.9779532398124364	[75]	[13,4,NaN]	-7	hSpCas9	negative selection	9965398
28272969	28272992	15	-	27869803	HPAFII	viability after 35 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.06253619461594837	[237]	[160,63,NaN]	0	hSpCas9	negative selection	9965399
28274377	28274400	15	+	27869803	HPAFII	viability after 35 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-1.1240160547487046	[131]	[56,0,NaN]	-6	hSpCas9	negative selection	9965400
28274912	28274935	15	-	27869803	HPAFII	viability after 35 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-2.234682880209771	[215]	[18,27,NaN]	-8	hSpCas9	negative selection	9965401
28280190	28280213	15	+	27869803	HPAFII	viability after 35 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.4463828333992004	[201]	[239,25,NaN]	3	hSpCas9	negative selection	9965402
28269285	28269308	15	-	27869803	HPAFII	viability after 31 days	TTCCTGATTCTGTCACGCAATGG	HERC2	ENSG00000128731	1.5988853277144757	[293]	[483,516,NaN]	9	hSpCas9	negative selection	10047846
28270727	28270750	15	+	27869803	HPAFII	viability after 31 days	GCATACAGGGCGTAGCCAGACGG	HERC2	ENSG00000128731	-2.471036796169087	[75]	[11,2,NaN]	-8	hSpCas9	negative selection	10047847
28272969	28272992	15	-	27869803	HPAFII	viability after 31 days	ACGCCAGCCACCAAAGGGCCAGG	HERC2	ENSG00000128731	-0.5427091162330069	[237]	[95,86,NaN]	-4	hSpCas9	negative selection	10047848
28274377	28274400	15	+	27869803	HPAFII	viability after 31 days	GGCCTCGGGAAGTGCTCGCAGGG	HERC2	ENSG00000128731	-1.0436764623426595	[131]	[67,0,NaN]	-6	hSpCas9	negative selection	10047849
28274912	28274935	15	-	27869803	HPAFII	viability after 31 days	TTGCCTTCCTGCGCAGGGCCTGG	HERC2	ENSG00000128731	-1.171407522947991	[215]	[60,45,NaN]	-6	hSpCas9	negative selection	10047850
28280190	28280213	15	+	27869803	HPAFII	viability after 31 days	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.061295918782616476	[201]	[178,31,NaN]	0	hSpCas9	negative selection	10047851
28263046	28263069	15	-	28162770	P31FUJ	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.6559410444838802	[383]	[710]	7	hSpCas9	negative selection	10168372
28280190	28280213	15	+	28162770	P31FUJ	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.6142169352167416	[163]	[294]	7	hSpCas9	negative selection	10168373
28256227	28256250	15	-	28162770	P31FUJ	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.591256175326855	[299]	[116]	-7	hSpCas9	negative selection	10168374
28246772	28246795	15	-	28162770	P31FUJ	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-0.08427967970429062	[248]	[275]	-1	hSpCas9	negative selection	10168375
28168513	28168536	15	+	28162770	P31FUJ	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.7946785320077288	[51]	[105]	8	hSpCas9	negative selection	10168376
28132222	28132245	15	+	28162770	P31FUJ	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	-0.21465485770411918	[78]	[79]	-2	hSpCas9	negative selection	10168377
28124065	28124088	15	+	28162770	P31FUJ	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	-0.10677255135203767	[481]	[525]	-1	hSpCas9	negative selection	10168378
28121349	28121372	15	+	28162770	P31FUJ	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	-0.1896414416254063	[460]	[474]	-2	hSpCas9	negative selection	10168379
28116750	28116773	15	-	28162770	P31FUJ	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.14270693067782775	[221]	[287]	1	hSpCas9	negative selection	10168380
28299401	28299424	15	-	28162770	P31FUJ	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.8780045814715561	[237]	[513]	8	hSpCas9	negative selection	10168381
28263046	28263069	15	-	28162770	TF1	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	NaN	[NaN]	[363]	1	hSpCas9	negative selection	10337738
28280190	28280213	15	+	28162770	TF1	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	NaN	[NaN]	[258]	1	hSpCas9	negative selection	10337739
28256227	28256250	15	-	28162770	TF1	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10337740
28246772	28246795	15	-	28162770	TF1	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	NaN	[NaN]	[409]	1	hSpCas9	negative selection	10337741
28168513	28168536	15	+	28162770	TF1	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10337742
28132222	28132245	15	+	28162770	TF1	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10337743
28124065	28124088	15	+	28162770	TF1	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	NaN	[NaN]	[404]	1	hSpCas9	negative selection	10337744
28121349	28121372	15	+	28162770	TF1	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10337745
28116750	28116773	15	-	28162770	TF1	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10337746
28299401	28299424	15	-	28162770	TF1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	NaN	[NaN]	[370]	1	hSpCas9	negative selection	10337747
28263046	28263069	15	-	28162770	SKM1	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.8275698841222272	[130]	[410]	7	hSpCas9	negative selection	10507104
28280190	28280213	15	+	28162770	SKM1	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.2350292470143733	[61]	[257]	9	hSpCas9	negative selection	10507105
28256227	28256250	15	-	28162770	SKM1	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.167137184070693	[93]	[73]	-7	hSpCas9	negative selection	10507106
28246772	28246795	15	-	28162770	SKM1	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	0.7766357395962271	[69]	[211]	7	hSpCas9	negative selection	10507107
28168513	28168536	15	+	28162770	SKM1	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	1.4867510081176236	[21]	[108]	9	hSpCas9	negative selection	10507108
28132222	28132245	15	+	28162770	SKM1	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.7806628044326096	[26]	[81]	7	hSpCas9	negative selection	10507109
28124065	28124088	15	+	28162770	SKM1	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.8570291270600591	[93]	[300]	7	hSpCas9	negative selection	10507110
28121349	28121372	15	+	28162770	SKM1	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.17799830197799438	[96]	[193]	1	hSpCas9	negative selection	10507111
28116750	28116773	15	-	28162770	SKM1	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.5682324102562655	[65]	[172]	5	hSpCas9	negative selection	10507112
28299401	28299424	15	-	28162770	SKM1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.9316426372908311	[42]	[144]	8	hSpCas9	negative selection	10507113
28263046	28263069	15	-	28162770	SKM1	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.8275698841222272	[130]	[410]	7	hSpCas9	negative selection	10676470
28280190	28280213	15	+	28162770	SKM1	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.2350292470143733	[61]	[257]	9	hSpCas9	negative selection	10676471
28256227	28256250	15	-	28162770	SKM1	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.167137184070693	[93]	[73]	-7	hSpCas9	negative selection	10676472
28246772	28246795	15	-	28162770	SKM1	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	0.7766357395962271	[69]	[211]	7	hSpCas9	negative selection	10676473
28168513	28168536	15	+	28162770	SKM1	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	1.4867510081176236	[21]	[108]	9	hSpCas9	negative selection	10676474
28132222	28132245	15	+	28162770	SKM1	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.7806628044326096	[26]	[81]	7	hSpCas9	negative selection	10676475
28124065	28124088	15	+	28162770	SKM1	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.8570291270600591	[93]	[300]	7	hSpCas9	negative selection	10676476
28121349	28121372	15	+	28162770	SKM1	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.17799830197799438	[96]	[193]	1	hSpCas9	negative selection	10676477
28116750	28116773	15	-	28162770	SKM1	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.5682324102562655	[65]	[172]	5	hSpCas9	negative selection	10676478
28299401	28299424	15	-	28162770	SKM1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.9316426372908311	[42]	[144]	8	hSpCas9	negative selection	10676479
28263046	28263069	15	-	28162770	PL21	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.5431591231104778	[420]	[266]	5	hSpCas9	negative selection	10845836
28280190	28280213	15	+	28162770	PL21	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.05066848901121437	[187]	[78]	0	hSpCas9	negative selection	10845837
28256227	28256250	15	-	28162770	PL21	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-0.20987981002289896	[286]	[107]	-1	hSpCas9	negative selection	10845838
28246772	28246795	15	-	28162770	PL21	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	1.5421752828252573	[227]	[288]	9	hSpCas9	negative selection	10845839
28168513	28168536	15	+	28162770	PL21	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.1176774542973471	[71]	[33]	1	hSpCas9	negative selection	10845840
28132222	28132245	15	+	28162770	PL21	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	-0.3076550257093764	[90]	[31]	-2	hSpCas9	negative selection	10845841
28124065	28124088	15	+	28162770	PL21	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.8490138790306694	[286]	[224]	7	hSpCas9	negative selection	10845842
28121349	28121372	15	+	28162770	PL21	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.5071944328951521	[311]	[192]	4	hSpCas9	negative selection	10845843
28116750	28116773	15	-	28162770	PL21	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	1.6190294392637705	[186]	[249]	9	hSpCas9	negative selection	10845844
28299401	28299424	15	-	28162770	PL21	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.23220082372161865	[177]	[90]	2	hSpCas9	negative selection	10845845
28263046	28263069	15	-	28162770	P31FUJ	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.6559410444838802	[383]	[710]	7	hSpCas9	negative selection	11015202
28280190	28280213	15	+	28162770	P31FUJ	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.6142169352167416	[163]	[294]	7	hSpCas9	negative selection	11015203
28256227	28256250	15	-	28162770	P31FUJ	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.591256175326855	[299]	[116]	-7	hSpCas9	negative selection	11015204
28246772	28246795	15	-	28162770	P31FUJ	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-0.08427967970429062	[248]	[275]	-1	hSpCas9	negative selection	11015205
28168513	28168536	15	+	28162770	P31FUJ	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.7946785320077288	[51]	[105]	8	hSpCas9	negative selection	11015206
28132222	28132245	15	+	28162770	P31FUJ	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	-0.21465485770411918	[78]	[79]	-2	hSpCas9	negative selection	11015207
28124065	28124088	15	+	28162770	P31FUJ	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	-0.10677255135203767	[481]	[525]	-1	hSpCas9	negative selection	11015208
28121349	28121372	15	+	28162770	P31FUJ	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	-0.1896414416254063	[460]	[474]	-2	hSpCas9	negative selection	11015209
28116750	28116773	15	-	28162770	P31FUJ	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.14270693067782775	[221]	[287]	1	hSpCas9	negative selection	11015210
28299401	28299424	15	-	28162770	P31FUJ	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.8780045814715561	[237]	[513]	8	hSpCas9	negative selection	11015211
28263046	28263069	15	-	28162770	OCIAML5	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.048777962476441505	[270]	[505]	0	hSpCas9	negative selection	11184568
28280190	28280213	15	+	28162770	OCIAML5	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.4246199355610125	[148]	[360]	3	hSpCas9	negative selection	11184569
28256227	28256250	15	-	28162770	OCIAML5	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-0.4606416288071036	[76]	[100]	-3	hSpCas9	negative selection	11184570
28246772	28246795	15	-	28162770	OCIAML5	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	0.4407151783638489	[99]	[244]	4	hSpCas9	negative selection	11184571
28168513	28168536	15	+	28162770	OCIAML5	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.5171672388017219	[35]	[92]	4	hSpCas9	negative selection	11184572
28132222	28132245	15	+	28162770	OCIAML5	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.09670810578083011	[42]	[82]	0	hSpCas9	negative selection	11184573
28124065	28124088	15	+	28162770	OCIAML5	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	-0.07907266751357667	[260]	[445]	0	hSpCas9	negative selection	11184574
28121349	28121372	15	+	28162770	OCIAML5	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.17092507176223215	[248]	[505]	1	hSpCas9	negative selection	11184575
28116750	28116773	15	-	28162770	OCIAML5	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	1.038145283597891	[115]	[429]	8	hSpCas9	negative selection	11184576
28299401	28299424	15	-	28162770	OCIAML5	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.16370074499431952	[181]	[367]	1	hSpCas9	negative selection	11184577
28263046	28263069	15	-	28162770	EOL1	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.46739229598894894	[949]	[691]	4	hSpCas9	negative selection	11353934
28280190	28280213	15	+	28162770	EOL1	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.22300941684332332	[287]	[129]	-2	hSpCas9	negative selection	11353935
28256227	28256250	15	-	28162770	EOL1	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-2.011993630576241	[466]	[60]	-8	hSpCas9	negative selection	11353936
28246772	28246795	15	-	28162770	EOL1	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-0.2908918891241466	[482]	[207]	-2	hSpCas9	negative selection	11353937
28168513	28168536	15	+	28162770	EOL1	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.126181632740185	[159]	[91]	1	hSpCas9	negative selection	11353938
28132222	28132245	15	+	28162770	EOL1	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	1.1329469208274825	[147]	[170]	8	hSpCas9	negative selection	11353939
28124065	28124088	15	+	28162770	EOL1	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.4196247687744957	[446]	[314]	4	hSpCas9	negative selection	11353940
28121349	28121372	15	+	28162770	EOL1	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.1065717337563577	[408]	[231]	1	hSpCas9	negative selection	11353941
28116750	28116773	15	-	28162770	EOL1	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	-0.12046196334703119	[292]	[141]	-1	hSpCas9	negative selection	11353942
28299401	28299424	15	-	28162770	EOL1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.3770599762680412	[246]	[168]	3	hSpCas9	negative selection	11353943
28263046	28263069	15	-	28162770	MOLM13	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.9809431281771364	[664]	[948]	7	hSpCas9	negative selection	11523300
28280190	28280213	15	+	28162770	MOLM13	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.37434861370515693	[222]	[208]	2	hSpCas9	negative selection	11523301
28256227	28256250	15	-	28162770	MOLM13	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-2.8792760048418065	[345]	[33]	-8	hSpCas9	negative selection	11523302
28246772	28246795	15	-	28162770	MOLM13	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	0.36676745710171277	[324]	[302]	2	hSpCas9	negative selection	11523303
28168513	28168536	15	+	28162770	MOLM13	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.14906719752503816	[115]	[92]	1	hSpCas9	negative selection	11523304
28132222	28132245	15	+	28162770	MOLM13	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	-0.7705153577805	[150]	[63]	-4	hSpCas9	negative selection	11523305
28124065	28124088	15	+	28162770	MOLM13	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.5958662009889203	[441]	[482]	4	hSpCas9	negative selection	11523306
28121349	28121372	15	+	28162770	MOLM13	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.4215957292706436	[474]	[459]	3	hSpCas9	negative selection	11523307
28116750	28116773	15	-	28162770	MOLM13	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.2007853114017379	[283]	[235]	1	hSpCas9	negative selection	11523308
28299401	28299424	15	-	28162770	MOLM13	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.3582648903700807	[204]	[189]	2	hSpCas9	negative selection	11523309
28263046	28263069	15	-	28162770	HEL	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	-1.050445070137936	[594]	[183]	-6	hSpCas9	negative selection	11692666
28280190	28280213	15	+	28162770	HEL	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.6982980858347101	[189]	[74]	-4	hSpCas9	negative selection	11692667
28256227	28256250	15	-	28162770	HEL	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.6832474794613588	[355]	[70]	-7	hSpCas9	negative selection	11692668
28246772	28246795	15	-	28162770	HEL	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-2.209162529010509	[295]	[40]	-8	hSpCas9	negative selection	11692669
28168513	28168536	15	+	28162770	HEL	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.6984482645866443	[126]	[131]	6	hSpCas9	negative selection	11692670
28132222	28132245	15	+	28162770	HEL	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	-1.8455476493091252	[100]	[17]	-7	hSpCas9	negative selection	11692671
28124065	28124088	15	+	28162770	HEL	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	-0.06960297519702663	[425]	[259]	0	hSpCas9	negative selection	11692672
28121349	28121372	15	+	28162770	HEL	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	-1.357261167999643	[323]	[80]	-7	hSpCas9	negative selection	11692673
28116750	28116773	15	-	28162770	HEL	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.13978474243743216	[264]	[186]	1	hSpCas9	negative selection	11692674
28299401	28299424	15	-	28162770	HEL	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.7842112579532374	[164]	[181]	6	hSpCas9	negative selection	11692675
28263046	28263069	15	-	28162770	MV411	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.8373289768342451	[486]	[732]	7	hSpCas9	negative selection	11862032
28280190	28280213	15	+	28162770	MV411	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.6777418067149297	[140]	[189]	6	hSpCas9	negative selection	11862033
28256227	28256250	15	-	28162770	MV411	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.5686610043468052	[330]	[93]	-7	hSpCas9	negative selection	11862034
28246772	28246795	15	-	28162770	MV411	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	0.9401138688041847	[171]	[277]	8	hSpCas9	negative selection	11862035
28168513	28168536	15	+	28162770	MV411	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	0.3189908118078094	[117]	[123]	3	hSpCas9	negative selection	11862036
28132222	28132245	15	+	28162770	MV411	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.5850189099816232	[109]	[138]	5	hSpCas9	negative selection	11862037
28124065	28124088	15	+	28162770	MV411	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.6431615750047852	[281]	[370]	6	hSpCas9	negative selection	11862038
28121349	28121372	15	+	28162770	MV411	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.2930601679085725	[248]	[256]	2	hSpCas9	negative selection	11862039
28116750	28116773	15	-	28162770	MV411	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	1.29647504409133	[187]	[388]	9	hSpCas9	negative selection	11862040
28299401	28299424	15	-	28162770	MV411	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.04875355635903902	[170]	[148]	0	hSpCas9	negative selection	11862041
28263046	28263069	15	-	28162770	MONOMAC1	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	-0.512132908464491	[315]	[253]	-4	hSpCas9	negative selection	12031398
28280190	28280213	15	+	28162770	MONOMAC1	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	0.19938497405194325	[116]	[153]	2	hSpCas9	negative selection	12031399
28256227	28256250	15	-	28162770	MONOMAC1	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-1.9949930711149082	[152]	[43]	-8	hSpCas9	negative selection	12031400
28246772	28246795	15	-	28162770	MONOMAC1	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-0.3111086137683484	[170]	[157]	-3	hSpCas9	negative selection	12031401
28168513	28168536	15	+	28162770	MONOMAC1	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	1.3879256536616025	[52]	[158]	9	hSpCas9	negative selection	12031402
28132222	28132245	15	+	28162770	MONOMAC1	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	-0.5428116839012838	[60]	[47]	-4	hSpCas9	negative selection	12031403
28124065	28124088	15	+	28162770	MONOMAC1	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.24868027030871676	[220]	[300]	2	hSpCas9	negative selection	12031404
28121349	28121372	15	+	28162770	MONOMAC1	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.18576031521908232	[180]	[235]	2	hSpCas9	negative selection	12031405
28116750	28116773	15	-	28162770	MONOMAC1	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	0.23861093189457616	[138]	[187]	2	hSpCas9	negative selection	12031406
28299401	28299424	15	-	28162770	MONOMAC1	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	-0.1970368470595536	[96]	[96]	-2	hSpCas9	negative selection	12031407
28263046	28263069	15	-	28162770	OCIAML2	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.12547323308419522	[85]	[519]	1	hSpCas9	negative selection	12200764
28280190	28280213	15	+	28162770	OCIAML2	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	-0.06537334675590288	[36]	[195]	0	hSpCas9	negative selection	12200765
28256227	28256250	15	-	28162770	OCIAML2	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-2.6632749031845573	[31]	[27]	-9	hSpCas9	negative selection	12200766
28246772	28246795	15	-	28162770	OCIAML2	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	-1.1861764357734619	[77]	[189]	-7	hSpCas9	negative selection	12200767
28168513	28168536	15	+	28162770	OCIAML2	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	-0.3966292437983844	[18]	[79]	-3	hSpCas9	negative selection	12200768
28132222	28132245	15	+	28162770	OCIAML2	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.022909647715400383	[18]	[106]	0	hSpCas9	negative selection	12200769
28124065	28124088	15	+	28162770	OCIAML2	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	-0.120596392674445	[60]	[310]	-1	hSpCas9	negative selection	12200770
28121349	28121372	15	+	28162770	OCIAML2	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.39812564147958623	[45]	[335]	4	hSpCas9	negative selection	12200771
28116750	28116773	15	-	28162770	OCIAML2	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	-0.8058140168317905	[40]	[129]	-5	hSpCas9	negative selection	12200772
28299401	28299424	15	-	28162770	OCIAML2	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	0.42884329880387423	[25]	[193]	4	hSpCas9	negative selection	12200773
28263046	28263069	15	-	28162770	OCIAML3	viability	GATGTGGTCAAAGTCCGCTGTGG	HERC2	ENSG00000128731	0.49494328258558506	[113]	[484]	4	hSpCas9	negative selection	12370130
28280190	28280213	15	+	28162770	OCIAML3	viability	GAGTCGCAGGGCTGAGAGGGTGG	HERC2	ENSG00000128731	1.3588583840847421	[34]	[270]	9	hSpCas9	negative selection	12370131
28256227	28256250	15	-	28162770	OCIAML3	viability	GAACAGCCTGAAGCAGACGGTGG	HERC2	ENSG00000128731	-0.48548318354599396	[63]	[137]	-4	hSpCas9	negative selection	12370132
28246772	28246795	15	-	28162770	OCIAML3	viability	CAGCTGGCGGCACTTCGCGGAGG	HERC2	ENSG00000128731	1.2071819089277263	[66]	[466]	8	hSpCas9	negative selection	12370133
28168513	28168536	15	+	28162770	OCIAML3	viability	GGGGCCGCCGAGGAGAACGAGGG	HERC2	ENSG00000128731	2.4733476274776014	[16]	[284]	9	hSpCas9	negative selection	12370134
28132222	28132245	15	+	28162770	OCIAML3	viability	AGGCGATGTCAACCACACGGTGG	HERC2	ENSG00000128731	0.5175006748928273	[27]	[120]	5	hSpCas9	negative selection	12370135
28124065	28124088	15	+	28162770	OCIAML3	viability	AGAGTGTCGAACCCAACAGAAGG	HERC2	ENSG00000128731	0.8447341195459491	[82]	[449]	7	hSpCas9	negative selection	12370136
28121349	28121372	15	+	28162770	OCIAML3	viability	GATGCGGTTCAGCTCCACGACGG	HERC2	ENSG00000128731	0.15685239550042374	[92]	[312]	1	hSpCas9	negative selection	12370137
28116750	28116773	15	-	28162770	OCIAML3	viability	TGATCGTGACACCCAACGGGAGG	HERC2	ENSG00000128731	1.177227855926789	[51]	[354]	8	hSpCas9	negative selection	12370138
28299401	28299424	15	-	28162770	OCIAML3	viability	GGAGAGCTCCCTCCTAGAAAAGG	HERC2	ENSG00000128731	1.0928344744162064	[40]	[263]	8	hSpCas9	negative selection	12370139