Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:26091
• Symbol:HERC4
• Description:HECT and RLD domain containing E3 ubiquitin protein ligase 4

DataSource: http://genomecrispr.dkfz.de/#!/results/HERC4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
67954701	67954724	10	-	26472758	Jiyoye	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.9225300639732081	[185]	[73]	-6	hSpCas9	negative selection	70236
67990239	67990262	10	+	26472758	Jiyoye	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	-0.6216794811663119	[201]	[98]	-4	hSpCas9	negative selection	70237
68025596	68025619	10	-	26472758	Jiyoye	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.8294083821889211	[99]	[133]	6	hSpCas9	negative selection	70238
67992292	67992315	10	+	26472758	Jiyoye	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.01732244702203678	[203]	[151]	0	hSpCas9	negative selection	70239
67955043	67955066	10	-	26472758	Jiyoye	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	3.294700652247461	[9]	[73]	9	hSpCas9	negative selection	70240
67932638	67932661	10	-	26472758	Jiyoye	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.23267765027373694	[78]	[69]	1	hSpCas9	negative selection	70241
68044423	68044446	10	-	26472758	Jiyoye	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-0.31308733386756304	[228]	[138]	-2	hSpCas9	negative selection	70242
68014142	68014165	10	+	26472758	Jiyoye	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.3597499144017593	[518]	[304]	-3	hSpCas9	negative selection	70243
68014090	68014113	10	-	26472758	Jiyoye	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-1.55805920033345	[163]	[41]	-7	hSpCas9	negative selection	70244
68014035	68014058	10	+	26472758	Jiyoye	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.5140905854223856	[51]	[55]	4	hSpCas9	negative selection	70245
67954701	67954724	10	-	26472758	KBM7	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.09138447326621346	[683,722]	[305,318]	-1	hSpCas9	negative selection	261354
67990239	67990262	10	+	26472758	KBM7	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.34057720004297	[711,562]	[369,382]	3	hSpCas9	negative selection	261355
68025596	68025619	10	-	26472758	KBM7	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.29956316889837753	[640,516]	[426,248]	3	hSpCas9	negative selection	261356
67992292	67992315	10	+	26472758	KBM7	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.4774902509113766	[687,600]	[269,169]	-4	hSpCas9	negative selection	261357
67955043	67955066	10	-	26472758	KBM7	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	0.8135464706613039	[266,184]	[85,271]	8	hSpCas9	negative selection	261358
67932638	67932661	10	-	26472758	KBM7	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	-0.3288618857751261	[263,316]	[151,72]	-3	hSpCas9	negative selection	261359
68044423	68044446	10	-	26472758	KBM7	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.6226193694297979	[923,1067]	[854,617]	6	hSpCas9	negative selection	261360
68014142	68014165	10	+	26472758	KBM7	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.3275965512051595	[1854,1638]	[947,1101]	3	hSpCas9	negative selection	261361
68014090	68014113	10	-	26472758	KBM7	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-0.06706857325789725	[523,385]	[238,168]	0	hSpCas9	negative selection	261362
68014035	68014058	10	+	26472758	KBM7	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	-0.056015814578923295	[490,323]	[89,262]	0	hSpCas9	negative selection	261363
67954701	67954724	10	-	26472758	Raji	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.1526793039289035	[387]	[80]	-1	hSpCas9	negative selection	452472
67990239	67990262	10	+	26472758	Raji	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.2742026259480902	[309]	[86]	2	hSpCas9	negative selection	452473
68025596	68025619	10	-	26472758	Raji	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.0019151071172121767	[232]	[53]	0	hSpCas9	negative selection	452474
67992292	67992315	10	+	26472758	Raji	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	0.030885397899556022	[425]	[100]	0	hSpCas9	negative selection	452475
67955043	67955066	10	-	26472758	Raji	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-1.5744405046001455	[153]	[11]	-8	hSpCas9	negative selection	452476
67932638	67932661	10	-	26472758	Raji	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	1.712523918032386	[70]	[53]	9	hSpCas9	negative selection	452477
68044423	68044446	10	-	26472758	Raji	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.43200573943022524	[427]	[133]	4	hSpCas9	negative selection	452478
68014142	68014165	10	+	26472758	Raji	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.17034475560322804	[1124]	[231]	-1	hSpCas9	negative selection	452479
68014090	68014113	10	-	26472758	Raji	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.7469812926716015	[189]	[73]	7	hSpCas9	negative selection	452480
68014035	68014058	10	+	26472758	Raji	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.21864028647534034	[236]	[63]	2	hSpCas9	negative selection	452481
67954701	67954724	10	-	26472758	K562	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.13829037680510348	[563]	[523]	1	hSpCas9	negative selection	643590
67990239	67990262	10	+	26472758	K562	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.8971154049350489	[422]	[664]	7	hSpCas9	negative selection	643591
68025596	68025619	10	-	26472758	K562	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.5451075409778702	[381]	[220]	-3	hSpCas9	negative selection	643592
67992292	67992315	10	+	26472758	K562	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.864335475913846	[784]	[363]	-5	hSpCas9	negative selection	643593
67955043	67955066	10	-	26472758	K562	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-1.1787927030580971	[235]	[87]	-6	hSpCas9	negative selection	643594
67932638	67932661	10	-	26472758	K562	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.7326405735492529	[220]	[309]	6	hSpCas9	negative selection	643595
68044423	68044446	10	-	26472758	K562	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.41369284029064046	[738]	[830]	3	hSpCas9	negative selection	643596
68014142	68014165	10	+	26472758	K562	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.005440289419614164	[1634]	[1374]	0	hSpCas9	negative selection	643597
68014090	68014113	10	-	26472758	K562	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.5132743722289613	[370]	[446]	4	hSpCas9	negative selection	643598
68014035	68014058	10	+	26472758	K562	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	-2.9765804583701345	[344]	[36]	-8	hSpCas9	negative selection	643599
67966694	67966717	10	-	26627737	DLD1	viability	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.9423904299036547	[398]	[200,187,315]	8	hSpCas9	negative selection	775327
67990903	67990926	10	-	26627737	DLD1	viability	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.25106864074914	[308]	[132,95,114]	2	hSpCas9	negative selection	775328
67991154	67991177	10	+	26627737	DLD1	viability	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	0.4777418210235377	[328]	[134,203,99]	5	hSpCas9	negative selection	775329
67992208	67992231	10	+	26627737	DLD1	viability	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.25071982525780884	[405]	[160,119,167]	2	hSpCas9	negative selection	775330
68034058	68034081	10	+	26627737	DLD1	viability	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.7042988911429446	[1095]	[530,656,499]	7	hSpCas9	negative selection	775331
68044477	68044500	10	-	26627737	DLD1	viability	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.6098069805356763	[136]	[48,33,4]	-5	hSpCas9	negative selection	775332
67966694	67966717	10	-	26627737	GBM cells	viability after 5 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.23312029955148464	[233]	[149,144]	3	hSpCas9	negative selection	857642
67990903	67990926	10	-	26627737	GBM cells	viability after 5 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.7874938893950163	[242]	[71,78]	-8	hSpCas9	negative selection	857643
67991154	67991177	10	+	26627737	GBM cells	viability after 5 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.15372760485554365	[306]	[160,134]	-2	hSpCas9	negative selection	857644
67992208	67992231	10	+	26627737	GBM cells	viability after 5 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.3055827929488531	[226]	[111,84]	-5	hSpCas9	negative selection	857645
68034058	68034081	10	+	26627737	GBM cells	viability after 5 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.03690487795801123	[806]	[401,485]	0	hSpCas9	negative selection	857646
68044477	68044500	10	-	26627737	GBM cells	viability after 5 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.12245977590688151	[135]	[85,47]	-2	hSpCas9	negative selection	857647
67966694	67966717	10	-	26627737	GBM cells	viability after 13 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.7175740450960004	[233]	[253,171]	8	hSpCas9	negative selection	939957
67990903	67990926	10	-	26627737	GBM cells	viability after 13 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.8626539794762065	[242]	[50,89]	-7	hSpCas9	negative selection	939958
67991154	67991177	10	+	26627737	GBM cells	viability after 13 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.1620340239276177	[306]	[176,125]	-2	hSpCas9	negative selection	939959
67992208	67992231	10	+	26627737	GBM cells	viability after 13 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.038085268216890705	[226]	[173,75]	0	hSpCas9	negative selection	939960
68034058	68034081	10	+	26627737	GBM cells	viability after 13 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.2990716516499916	[806]	[605,483]	4	hSpCas9	negative selection	939961
68044477	68044500	10	-	26627737	GBM cells	viability after 13 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.12159842282418631	[135]	[87,73]	1	hSpCas9	negative selection	939962
67966694	67966717	10	-	26627737	GBM cells	viability after 21 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.782897862942155	[233]	[224,212]	7	hSpCas9	negative selection	1022272
67990903	67990926	10	-	26627737	GBM cells	viability after 21 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.6589564337853703	[242]	[80,85]	-5	hSpCas9	negative selection	1022273
67991154	67991177	10	+	26627737	GBM cells	viability after 21 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.47818050662189243	[306]	[125,113]	-4	hSpCas9	negative selection	1022274
67992208	67992231	10	+	26627737	GBM cells	viability after 21 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.6449714249439866	[226]	[81,75]	-5	hSpCas9	negative selection	1022275
68034058	68034081	10	+	26627737	GBM cells	viability after 21 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.10025716875875346	[806]	[493,447]	1	hSpCas9	negative selection	1022276
68044477	68044500	10	-	26627737	GBM cells	viability after 21 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.6544777449511752	[135]	[120,111]	6	hSpCas9	negative selection	1022277
67966694	67966717	10	-	26627737	RPE1	viability after 9 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.9844075718271487	[271]	[157,181]	6	hSpCas9	negative selection	1104587
67990903	67990926	10	-	26627737	RPE1	viability after 9 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.4069930777243831	[211]	[46,53]	-3	hSpCas9	negative selection	1104588
67991154	67991177	10	+	26627737	RPE1	viability after 9 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-1.525269584027668	[694]	[27,136]	-8	hSpCas9	negative selection	1104589
67992208	67992231	10	+	26627737	RPE1	viability after 9 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.9487942375069693	[676]	[135,75]	-6	hSpCas9	negative selection	1104590
68034058	68034081	10	+	26627737	RPE1	viability after 9 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.5451826122402408	[3334]	[1323,1780]	4	hSpCas9	negative selection	1104591
68044477	68044500	10	-	26627737	RPE1	viability after 9 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.6276290801014797	[604]	[136,103]	-4	hSpCas9	negative selection	1104592
67966694	67966717	10	-	26627737	RPE1	viability after 12 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.8096143375285203	[271]	[130,124]	5	hSpCas9	negative selection	1186902
67990903	67990926	10	-	26627737	RPE1	viability after 12 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.5411318819871387	[211]	[60,15]	-4	hSpCas9	negative selection	1186903
67991154	67991177	10	+	26627737	RPE1	viability after 12 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.6701715409036426	[694]	[162,68]	-4	hSpCas9	negative selection	1186904
67992208	67992231	10	+	26627737	RPE1	viability after 12 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.9855806066315158	[676]	[86,96]	-6	hSpCas9	negative selection	1186905
68034058	68034081	10	+	26627737	RPE1	viability after 12 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.3918219143651607	[3334]	[1076,1279]	2	hSpCas9	negative selection	1186906
68044477	68044500	10	-	26627737	RPE1	viability after 12 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.8960621005468155	[604]	[64,110]	-6	hSpCas9	negative selection	1186907
67966694	67966717	10	-	26627737	RPE1	viability after 15 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.9877431729756132	[271]	[175,129]	6	hSpCas9	negative selection	1269217
67990903	67990926	10	-	26627737	RPE1	viability after 15 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.2780683595234692	[211]	[79,19]	-2	hSpCas9	negative selection	1269218
67991154	67991177	10	+	26627737	RPE1	viability after 15 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-1.5676714168465713	[694]	[19,110]	-7	hSpCas9	negative selection	1269219
67992208	67992231	10	+	26627737	RPE1	viability after 15 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-2.51634363301325	[676]	[34,31]	-8	hSpCas9	negative selection	1269220
68034058	68034081	10	+	26627737	RPE1	viability after 15 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.4815850974060356	[3334]	[1415,1221]	3	hSpCas9	negative selection	1269221
68044477	68044500	10	-	26627737	RPE1	viability after 15 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-1.0471525016227072	[604]	[92,72]	-6	hSpCas9	negative selection	1269222
67966694	67966717	10	-	26627737	RPE1	viability after 18 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.3495751289236837	[271]	[108,76]	2	hSpCas9	negative selection	1351532
67990903	67990926	10	-	26627737	RPE1	viability after 18 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.14400572389431887	[211]	[88,11]	-1	hSpCas9	negative selection	1351533
67991154	67991177	10	+	26627737	RPE1	viability after 18 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-1.5654803498835022	[694]	[44,82]	-7	hSpCas9	negative selection	1351534
67992208	67992231	10	+	26627737	RPE1	viability after 18 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-2.842930829474322	[676]	[38,10]	-9	hSpCas9	negative selection	1351535
68034058	68034081	10	+	26627737	RPE1	viability after 18 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.442014500973805	[3334]	[1110,1341]	3	hSpCas9	negative selection	1351536
68044477	68044500	10	-	26627737	RPE1	viability after 18 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.9974954074455213	[604]	[118,41]	-6	hSpCas9	negative selection	1351537
67966694	67966717	10	-	26627737	HeLa	viability after 8 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	-0.8771370462140314	[331]	[123,58,63]	-7	hSpCas9	negative selection	1433847
67990903	67990926	10	-	26627737	HeLa	viability after 8 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.4351999701651942	[233]	[154,35,53]	-4	hSpCas9	negative selection	1433848
67991154	67991177	10	+	26627737	HeLa	viability after 8 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.5750406181783002	[419]	[152,132,90]	-5	hSpCas9	negative selection	1433849
67992208	67992231	10	+	26627737	HeLa	viability after 8 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-1.1327547022727342	[512]	[114,86,105]	-8	hSpCas9	negative selection	1433850
68034058	68034081	10	+	26627737	HeLa	viability after 8 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.025880784087644715	[1408]	[607,554,641]	0	hSpCas9	negative selection	1433851
68044477	68044500	10	-	26627737	HeLa	viability after 8 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.8515382629737378	[163]	[159,86,144]	7	hSpCas9	negative selection	1433852
67966694	67966717	10	-	26627737	HeLa	viability after 12 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.30044579087297085	[331]	[98,214,185]	2	hSpCas9	negative selection	1516162
67990903	67990926	10	-	26627737	HeLa	viability after 12 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.509745195961538	[233]	[225,86,107]	4	hSpCas9	negative selection	1516163
67991154	67991177	10	+	26627737	HeLa	viability after 12 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.45108898274844045	[419]	[69,166,137]	-4	hSpCas9	negative selection	1516164
67992208	67992231	10	+	26627737	HeLa	viability after 12 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.9456577234041388	[512]	[175,82,75]	-7	hSpCas9	negative selection	1516165
68034058	68034081	10	+	26627737	HeLa	viability after 12 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.5358016892443069	[1408]	[374,374,456]	-5	hSpCas9	negative selection	1516166
68044477	68044500	10	-	26627737	HeLa	viability after 12 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	1.026879514523883	[163]	[102,102,210]	7	hSpCas9	negative selection	1516167
67966694	67966717	10	-	26627737	HeLa	viability after 15 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	-0.35617449185901595	[331]	[9,129,183]	-3	hSpCas9	negative selection	1598477
67990903	67990926	10	-	26627737	HeLa	viability after 15 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.7666764721926412	[233]	[66,66,31]	-6	hSpCas9	negative selection	1598478
67991154	67991177	10	+	26627737	HeLa	viability after 15 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	0.07610179563458733	[419]	[51,338,148]	0	hSpCas9	negative selection	1598479
67992208	67992231	10	+	26627737	HeLa	viability after 15 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-1.0155353718618914	[512]	[234,56,8]	-7	hSpCas9	negative selection	1598480
68034058	68034081	10	+	26627737	HeLa	viability after 15 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.3898713020643385	[1408]	[600,250,460]	-3	hSpCas9	negative selection	1598481
68044477	68044500	10	-	26627737	HeLa	viability after 15 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.04624252186293987	[163]	[16,107,69]	0	hSpCas9	negative selection	1598482
67966694	67966717	10	-	26627737	HeLa	viability after 18 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	-0.36338757897414076	[331]	[6,105,183]	-3	hSpCas9	negative selection	1680792
67990903	67990926	10	-	26627737	HeLa	viability after 18 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.833601839369973	[233]	[41,52,31]	-6	hSpCas9	negative selection	1680793
67991154	67991177	10	+	26627737	HeLa	viability after 18 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	0.057669879134641194	[419]	[34,274,148]	0	hSpCas9	negative selection	1680794
67992208	67992231	10	+	26627737	HeLa	viability after 18 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-1.010056067327631	[512]	[152,53,8]	-7	hSpCas9	negative selection	1680795
68034058	68034081	10	+	26627737	HeLa	viability after 18 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.3645446986584442	[1408]	[410,216,460]	-3	hSpCas9	negative selection	1680796
68044477	68044500	10	-	26627737	HeLa	viability after 18 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.06876072732053706	[163]	[12,84,69]	0	hSpCas9	negative selection	1680797
67966694	67966717	10	-	26627737	HCT116	viability after 6 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	-2.3225635757460306	[742]	[52,6]	-8	hSpCas9	negative selection	1763107
67990903	67990926	10	-	26627737	HCT116	viability after 6 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.8815496591396581	[219]	[50,0]	-5	hSpCas9	negative selection	1763108
67991154	67991177	10	+	26627737	HCT116	viability after 6 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	1.2868057986730532	[546]	[145,244]	7	hSpCas9	negative selection	1763109
67992208	67992231	10	+	26627737	HCT116	viability after 6 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.08356843107407189	[496]	[134,53]	0	hSpCas9	negative selection	1763110
68034058	68034081	10	+	26627737	HCT116	viability after 6 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.6610764593976715	[1723]	[318,89]	-4	hSpCas9	negative selection	1763111
68044477	68044500	10	-	26627737	HCT116	viability after 6 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.435699274947727	[758]	[94,197]	2	hSpCas9	negative selection	1763112
67966694	67966717	10	-	26627737	HCT116	viability after 8 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.14550215265349495	[291]	[212,180,140]	1	hSpCas9	negative selection	1845422
67990903	67990926	10	-	26627737	HCT116	viability after 8 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.11505917291904694	[212]	[80,129,168]	1	hSpCas9	negative selection	1845423
67991154	67991177	10	+	26627737	HCT116	viability after 8 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.9065399807424455	[367]	[97,89,135]	-8	hSpCas9	negative selection	1845424
67992208	67992231	10	+	26627737	HCT116	viability after 8 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.15745406673919382	[179]	[84,115,65]	-2	hSpCas9	negative selection	1845425
68034058	68034081	10	+	26627737	HCT116	viability after 8 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.006866136588395744	[925]	[512,424,598]	0	hSpCas9	negative selection	1845426
68044477	68044500	10	-	26627737	HCT116	viability after 8 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.05551029414102149	[193]	[167,30,134]	0	hSpCas9	negative selection	1845427
67966694	67966717	10	-	26627737	HCT116	viability after 9 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.1839190483898066	[742]	[383,99]	1	hSpCas9	negative selection	1927737
67990903	67990926	10	-	26627737	HCT116	viability after 9 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	1.380253193596112	[219]	[229,91]	8	hSpCas9	negative selection	1927738
67991154	67991177	10	+	26627737	HCT116	viability after 9 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-1.1054312813040075	[546]	[68,66]	-7	hSpCas9	negative selection	1927739
67992208	67992231	10	+	26627737	HCT116	viability after 9 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-2.444581972582386	[496]	[15,30]	-9	hSpCas9	negative selection	1927740
68034058	68034081	10	+	26627737	HCT116	viability after 9 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.3789119827169296	[1723]	[372,338]	-3	hSpCas9	negative selection	1927741
68044477	68044500	10	-	26627737	HCT116	viability after 9 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.8908523477879329	[758]	[115,103]	-6	hSpCas9	negative selection	1927742
67966694	67966717	10	-	26627737	HCT116	viability after 12 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.10777836911338248	[291]	[191,93,205]	1	hSpCas9	negative selection	2010052
67990903	67990926	10	-	26627737	HCT116	viability after 12 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.10285151856729424	[212]	[76,58,177]	-1	hSpCas9	negative selection	2010053
67991154	67991177	10	+	26627737	HCT116	viability after 12 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-1.1367394399345931	[367]	[67,103,93]	-8	hSpCas9	negative selection	2010054
67992208	67992231	10	+	26627737	HCT116	viability after 12 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.12060422145959604	[179]	[48,215,50]	1	hSpCas9	negative selection	2010055
68034058	68034081	10	+	26627737	HCT116	viability after 12 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.008195286833277748	[925]	[407,679,391]	0	hSpCas9	negative selection	2010056
68044477	68044500	10	-	26627737	HCT116	viability after 12 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.35585610729462613	[193]	[57,124,58]	-4	hSpCas9	negative selection	2010057
67966694	67966717	10	-	26627737	HCT116	viability after 15 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	-0.31754514843312875	[291]	[206,111,93]	-3	hSpCas9	negative selection	2092367
67990903	67990926	10	-	26627737	HCT116	viability after 15 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.4908654395848609	[212]	[249,85,188]	4	hSpCas9	negative selection	2092368
67991154	67991177	10	+	26627737	HCT116	viability after 15 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.764999004396911	[367]	[137,49,185]	-7	hSpCas9	negative selection	2092369
67992208	67992231	10	+	26627737	HCT116	viability after 15 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.5574332538093185	[179]	[176,178,103]	5	hSpCas9	negative selection	2092370
68034058	68034081	10	+	26627737	HCT116	viability after 15 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.11652259556475997	[925]	[420,456,583]	-1	hSpCas9	negative selection	2092371
68044477	68044500	10	-	26627737	HCT116	viability after 15 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.2128091270478677	[193]	[125,66,98]	-2	hSpCas9	negative selection	2092372
67966694	67966717	10	-	26627737	HCT116	viability after 18 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.09690115575425656	[291]	[223,68,165]	0	hSpCas9	negative selection	2174682
67990903	67990926	10	-	26627737	HCT116	viability after 18 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.06153510621791203	[212]	[118,81,95]	0	hSpCas9	negative selection	2174683
67991154	67991177	10	+	26627737	HCT116	viability after 18 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-1.2071981034677588	[367]	[72,62,96]	-8	hSpCas9	negative selection	2174684
67992208	67992231	10	+	26627737	HCT116	viability after 18 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.4618892422520474	[179]	[45,91,48]	-4	hSpCas9	negative selection	2174685
68034058	68034081	10	+	26627737	HCT116	viability after 18 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.20539680056507637	[925]	[410,520,620]	1	hSpCas9	negative selection	2174686
68044477	68044500	10	-	26627737	HCT116	viability after 18 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.17622657906495964	[193]	[58,92,96]	-2	hSpCas9	negative selection	2174687
68072909	68072932	10	-	24336569	HL60	viability	TGTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	-0.26525282761078495	[463]	[816]	-2	hSpCas9	negative selection	2269414
68072918	68072941	10	-	24336569	HL60	viability	ACATGTGGATGTAATGATCTAGG	HERC4	ENSG00000148634	0.7082085438681542	[386]	[1337]	6	hSpCas9	negative selection	2269415
68072933	68072956	10	-	24336569	HL60	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.29275151577455316	[801]	[2078]	2	hSpCas9	negative selection	2269416
68072951	68072974	10	-	24336569	HL60	viability	ACTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	-0.3951434878484519	[544]	[876]	-4	hSpCas9	negative selection	2269417
68072958	68072981	10	-	24336569	HL60	viability	CAGACATACTGTGTTTGTTCTGG	HERC4	ENSG00000148634	-1.457137767287785	[710]	[547]	-8	hSpCas9	negative selection	2269418
68072979	68073002	10	+	24336569	HL60	viability	TGAGTCCACATCCTACATCTCGG	HERC4	ENSG00000148634	-0.3410123306844429	[743]	[1242]	-3	hSpCas9	negative selection	2269419
68072984	68073007	10	-	24336569	HL60	viability	AGGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	-0.5280316149897457	[1911]	[2805]	-5	hSpCas9	negative selection	2269420
68073062	68073085	10	-	24336569	HL60	viability	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	0.45845192031532533	[552]	[1607]	4	hSpCas9	negative selection	2269421
68073071	68073094	10	-	24336569	HL60	viability	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.5747356240062356	[269]	[850]	5	hSpCas9	negative selection	2269422
68073096	68073119	10	-	24336569	HL60	viability	AATTACAAGCATGTTGTGCTGGG	HERC4	ENSG00000148634	1.7591179940794222	[232]	[1668]	9	hSpCas9	negative selection	2269423
68072909	68072932	10	-	24336569	KBM7	viability	TGTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	-0.8160440578135619	[507]	[786]	-6	hSpCas9	negative selection	2336591
68072918	68072941	10	-	24336569	KBM7	viability	ACATGTGGATGTAATGATCTAGG	HERC4	ENSG00000148634	-0.06474698243356104	[435]	[1136]	0	hSpCas9	negative selection	2336592
68072933	68072956	10	-	24336569	KBM7	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.5471887956995103	[696]	[1300]	-4	hSpCas9	negative selection	2336593
68072951	68072974	10	-	24336569	KBM7	viability	ACTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	-0.49943491618331826	[523]	[1010]	-4	hSpCas9	negative selection	2336594
68072958	68072981	10	-	24336569	KBM7	viability	CAGACATACTGTGTTTGTTCTGG	HERC4	ENSG00000148634	-0.2433990882400089	[762]	[1757]	-2	hSpCas9	negative selection	2336595
68072979	68073002	10	+	24336569	KBM7	viability	TGAGTCCACATCCTACATCTCGG	HERC4	ENSG00000148634	0.7897874394825801	[266]	[1258]	7	hSpCas9	negative selection	2336596
68072984	68073007	10	-	24336569	KBM7	viability	AGGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.0482906646538368	[1346]	[3798]	0	hSpCas9	negative selection	2336597
68073062	68073085	10	-	24336569	KBM7	viability	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	1.1601033806723573	[314]	[1919]	8	hSpCas9	negative selection	2336598
68073071	68073094	10	-	24336569	KBM7	viability	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.8602908573509853	[164]	[816]	7	hSpCas9	negative selection	2336599
68073096	68073119	10	-	24336569	KBM7	viability	AATTACAAGCATGTTGTGCTGGG	HERC4	ENSG00000148634	-0.7893062340052837	[696]	[1099]	-6	hSpCas9	negative selection	2336600
67949976	67949999	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCACTGCACTCCAGCCTGGAGG	HERC4	ENSG00000148634	1.049956001898007	[3,11]	[2,3]	4	dCas9-VP64	positive selection	2389127
68061630	68061653	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGGAGGCAGAGACGGG	HERC4	ENSG00000148634	-0.1382628736712302	[122,32]	[23,4]	0	dCas9-VP64	positive selection	2412940
67983680	67983703	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGGCTGAGGCAGGAGAACAG	HERC4	ENSG00000148634	-0.8896445471743792	[26,0]	[0,0]	-5	dCas9-VP64	positive selection	2422168
67949256	67949279	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGTCTCACTTTGTCACCCCAG	HERC4	ENSG00000148634	0.26093867819462435	[136,84]	[48,7]	1	dCas9-VP64	positive selection	2453461
68026808	68026831	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACTCCAGCCTGGGCGACAGAAAG	HERC4	ENSG00000148634	1.2012671036636573	[14,1]	[1,5]	5	dCas9-VP64	positive selection	2454914
68070539	68070562	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCGGTGAGCCGAGATGG	HERC4	ENSG00000148634	2.3233621518244867	[14,12]	[9,20]	7	dCas9-VP64	positive selection	2460607
67931656	67931679	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCGCCCACCTTGG	HERC4	ENSG00000148634	-1.8266088487663314	[149,166]	[13,3]	-8	dCas9-VP64	positive selection	2465219
67924252	67924275	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CATAGCATTTACATTGTATGAGG	HERC4	ENSG00000148634	1.9981686994039458	[69,86]	[126,6]	7	dCas9-VP64	positive selection	2474298
68061814	68061837	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCAGTGAGCCGAGATGG	HERC4	ENSG00000148634	0.6330757747468561	[50,16]	[8,13]	2	dCas9-VP64	positive selection	2476967
67940560	67940583	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGGGCCACCACGCCTGG	HERC4	ENSG00000148634	2.170805682876019	[0,2]	[0,2]	7	dCas9-VP64	positive selection	2477277
67949976	67949999	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCACTGCACTCCAGCCTGGAGG	HERC4	ENSG00000148634	0.3100958641524221	[17,26]	[5,11]	2	dCas9-VP64	positive selection	2484382
68061630	68061653	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGGAGGCAGAGACGGG	HERC4	ENSG00000148634	0.5826032865103569	[42,50]	[25,19]	4	dCas9-VP64	positive selection	2508195
67983680	67983703	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGGCTGAGGCAGGAGAACAG	HERC4	ENSG00000148634	0.4958448470370793	[21,20]	[10,7]	4	dCas9-VP64	positive selection	2517423
67949256	67949279	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGTCTCACTTTGTCACCCCAG	HERC4	ENSG00000148634	-0.29461815944737046	[252,104]	[71,24]	-3	dCas9-VP64	positive selection	2548716
68026808	68026831	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACTCCAGCCTGGGCGACAGAAAG	HERC4	ENSG00000148634	0.32779538109836626	[14,14]	[4,6]	2	dCas9-VP64	positive selection	2550169
68070539	68070562	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCGGTGAGCCGAGATGG	HERC4	ENSG00000148634	1.0057399992234806	[75,12]	[21,35]	6	dCas9-VP64	positive selection	2555862
67931656	67931679	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCGCCCACCTTGG	HERC4	ENSG00000148634	0.6108739619638027	[154,293]	[174,51]	4	dCas9-VP64	positive selection	2560474
67924252	67924275	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CATAGCATTTACATTGTATGAGG	HERC4	ENSG00000148634	3.112413163684098	[124,172]	[483,360]	9	dCas9-VP64	positive selection	2569553
68061814	68061837	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCAGTGAGCCGAGATGG	HERC4	ENSG00000148634	0.34517561365305327	[29,16]	[7,9]	2	dCas9-VP64	positive selection	2572222
67940560	67940583	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGGGCCACCACGCCTGG	HERC4	ENSG00000148634	-0.9433721542686317	[3,48]	[3,3]	-8	dCas9-VP64	positive selection	2572532
68073064	68073087	10	+	27260157	DLD1	viability	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	0.289678114487976	[]	[]	4	hSpCas9	negative selection	2574893
68044423	68044446	10	-	27260157	DLD1	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-0.110685980293766	[]	[]	-1	hSpCas9	negative selection	2576189
68072984	68073007	10	-	27260157	DLD1	viability	AGGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	-0.39010396876262	[]	[]	-3	hSpCas9	negative selection	2577276
68034087	68034110	10	+	27260157	DLD1	viability	AGCAAAGACTTAAGCAGCTGCGG	HERC4	ENSG00000148634	-0.485168721135056	[]	[]	-4	hSpCas9	negative selection	2582962
68072958	68072981	10	-	27260157	DLD1	viability	CAGACATACTGTGTTTGTTCTGG	HERC4	ENSG00000148634	-0.244023347448587	[]	[]	-2	hSpCas9	negative selection	2585696
68072918	68072941	10	-	27260157	DLD1	viability	ACATGTGGATGTAATGATCTAGG	HERC4	ENSG00000148634	0.0125278616533588	[]	[]	0	hSpCas9	negative selection	2605250
68038122	68038145	10	-	27260157	DLD1	viability	CAGATTGTACAGGTTGCTTGTGG	HERC4	ENSG00000148634	-0.406859259260831	[]	[]	-3	hSpCas9	negative selection	2608615
68044435	68044458	10	-	27260157	DLD1	viability	TTCTGATGGACAGCTTGGCCTGG	HERC4	ENSG00000148634	0.518387679358036	[]	[]	8	hSpCas9	negative selection	2608807
68073096	68073119	10	-	27260157	DLD1	viability	AATTACAAGCATGTTGTGCTGGG	HERC4	ENSG00000148634	-0.191675528854649	[]	[]	-1	hSpCas9	negative selection	2609456
68044546	68044569	10	-	27260157	DLD1	viability	TGTAGAGCAGGTTGTTGCCCTGG	HERC4	ENSG00000148634	-0.158834988197346	[]	[]	-1	hSpCas9	negative selection	2611810
68072951	68072974	10	-	27260157	DLD1	viability	ACTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	1.15739023247395	[]	[]	9	hSpCas9	negative selection	2618892
68038123	68038146	10	+	27260157	DLD1	viability	CACAAGCAACCTGTACAATCTGG	HERC4	ENSG00000148634	0.0235851383875468	[]	[]	0	hSpCas9	negative selection	2619366
68044477	68044500	10	-	27260157	DLD1	viability	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.268384396013456	[]	[]	4	hSpCas9	negative selection	2619416
68073062	68073085	10	-	27260157	DLD1	viability	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	0.52593033171028	[]	[]	8	hSpCas9	negative selection	2619632
68044417	68044440	10	+	27260157	DLD1	viability	TGCATTCCTCTGATCCTACCAGG	HERC4	ENSG00000148634	0.742030725287168	[]	[]	8	hSpCas9	negative selection	2621400
68073071	68073094	10	-	27260157	DLD1	viability	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.1633567586888	[]	[]	3	hSpCas9	negative selection	2643995
68072979	68073002	10	+	27260157	DLD1	viability	TGAGTCCACATCCTACATCTCGG	HERC4	ENSG00000148634	0.155102039509048	[]	[]	3	hSpCas9	negative selection	2646308
68072909	68072932	10	-	27260157	DLD1	viability	TGTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	1.15559636417022	[]	[]	9	hSpCas9	negative selection	2646568
68072933	68072956	10	-	27260157	DLD1	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.869341350067691	[]	[]	-6	hSpCas9	negative selection	2648229
68073064	68073087	10	+	27260157	HT1080	viability	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	0.130536442808185	[]	[]	1	hSpCas9	negative selection	2651023
68044423	68044446	10	-	27260157	HT1080	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-0.742429111028437	[]	[]	-8	hSpCas9	negative selection	2652319
68072984	68073007	10	-	27260157	HT1080	viability	AGGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	-1.19418528809425	[]	[]	-8	hSpCas9	negative selection	2653406
68034087	68034110	10	+	27260157	HT1080	viability	AGCAAAGACTTAAGCAGCTGCGG	HERC4	ENSG00000148634	0.443968574129963	[]	[]	4	hSpCas9	negative selection	2659092
68072958	68072981	10	-	27260157	HT1080	viability	CAGACATACTGTGTTTGTTCTGG	HERC4	ENSG00000148634	-0.372153120816524	[]	[]	-7	hSpCas9	negative selection	2661826
68072918	68072941	10	-	27260157	HT1080	viability	ACATGTGGATGTAATGATCTAGG	HERC4	ENSG00000148634	-0.368978887050737	[]	[]	-7	hSpCas9	negative selection	2681380
68038122	68038145	10	-	27260157	HT1080	viability	CAGATTGTACAGGTTGCTTGTGG	HERC4	ENSG00000148634	0.264511351373191	[]	[]	2	hSpCas9	negative selection	2684745
68044435	68044458	10	-	27260157	HT1080	viability	TTCTGATGGACAGCTTGGCCTGG	HERC4	ENSG00000148634	0.364411136486035	[]	[]	3	hSpCas9	negative selection	2684937
68073096	68073119	10	-	27260157	HT1080	viability	AATTACAAGCATGTTGTGCTGGG	HERC4	ENSG00000148634	0.0543038558810648	[]	[]	0	hSpCas9	negative selection	2685586
68044546	68044569	10	-	27260157	HT1080	viability	TGTAGAGCAGGTTGTTGCCCTGG	HERC4	ENSG00000148634	-0.452547566758622	[]	[]	-7	hSpCas9	negative selection	2687940
68072951	68072974	10	-	27260157	HT1080	viability	ACTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	-0.16714818312092	[]	[]	0	hSpCas9	negative selection	2695022
68038123	68038146	10	+	27260157	HT1080	viability	CACAAGCAACCTGTACAATCTGG	HERC4	ENSG00000148634	0.432993531071903	[]	[]	4	hSpCas9	negative selection	2695496
68044477	68044500	10	-	27260157	HT1080	viability	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.466228802556918	[]	[]	-7	hSpCas9	negative selection	2695546
68073062	68073085	10	-	27260157	HT1080	viability	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	-0.484544575028029	[]	[]	-7	hSpCas9	negative selection	2695762
68044417	68044440	10	+	27260157	HT1080	viability	TGCATTCCTCTGATCCTACCAGG	HERC4	ENSG00000148634	0.0418891476427609	[]	[]	0	hSpCas9	negative selection	2697530
68073071	68073094	10	-	27260157	HT1080	viability	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.456531430101164	[]	[]	4	hSpCas9	negative selection	2720125
68072979	68073002	10	+	27260157	HT1080	viability	TGAGTCCACATCCTACATCTCGG	HERC4	ENSG00000148634	-0.222859631952507	[]	[]	0	hSpCas9	negative selection	2722438
68072909	68072932	10	-	27260157	HT1080	viability	TGTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.125781875654853	[]	[]	1	hSpCas9	negative selection	2722698
68072933	68072956	10	-	27260157	HT1080	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.951597268804312	[]	[]	-8	hSpCas9	negative selection	2724359
68073064	68073087	10	+	27260157	MKN45	viability	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	-0.114072688340255	[]	[]	0	hSpCas9	negative selection	2727153
68044423	68044446	10	-	27260157	MKN45	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-1.2602369548959	[]	[]	-8	hSpCas9	negative selection	2728449
68072984	68073007	10	-	27260157	MKN45	viability	AGGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.0981020088014769	[]	[]	0	hSpCas9	negative selection	2729536
68034087	68034110	10	+	27260157	MKN45	viability	AGCAAAGACTTAAGCAGCTGCGG	HERC4	ENSG00000148634	-0.0619660060188957	[]	[]	0	hSpCas9	negative selection	2735222
68072958	68072981	10	-	27260157	MKN45	viability	CAGACATACTGTGTTTGTTCTGG	HERC4	ENSG00000148634	-0.916287604747993	[]	[]	-7	hSpCas9	negative selection	2737956
68072918	68072941	10	-	27260157	MKN45	viability	ACATGTGGATGTAATGATCTAGG	HERC4	ENSG00000148634	-0.85071690677302	[]	[]	-7	hSpCas9	negative selection	2757510
68038122	68038145	10	-	27260157	MKN45	viability	CAGATTGTACAGGTTGCTTGTGG	HERC4	ENSG00000148634	0.199571471201606	[]	[]	5	hSpCas9	negative selection	2760875
68044435	68044458	10	-	27260157	MKN45	viability	TTCTGATGGACAGCTTGGCCTGG	HERC4	ENSG00000148634	0.735009494626737	[]	[]	7	hSpCas9	negative selection	2761067
68073096	68073119	10	-	27260157	MKN45	viability	AATTACAAGCATGTTGTGCTGGG	HERC4	ENSG00000148634	1.05741178584597	[]	[]	8	hSpCas9	negative selection	2761716
68044546	68044569	10	-	27260157	MKN45	viability	TGTAGAGCAGGTTGTTGCCCTGG	HERC4	ENSG00000148634	-1.03239467404469	[]	[]	-8	hSpCas9	negative selection	2764070
68072951	68072974	10	-	27260157	MKN45	viability	ACTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	-0.576778967986745	[]	[]	-6	hSpCas9	negative selection	2771152
68038123	68038146	10	+	27260157	MKN45	viability	CACAAGCAACCTGTACAATCTGG	HERC4	ENSG00000148634	0.634946304348254	[]	[]	7	hSpCas9	negative selection	2771626
68044477	68044500	10	-	27260157	MKN45	viability	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.197391511069609	[]	[]	5	hSpCas9	negative selection	2771676
68073062	68073085	10	-	27260157	MKN45	viability	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	-0.230234350937793	[]	[]	-1	hSpCas9	negative selection	2771892
68044417	68044440	10	+	27260157	MKN45	viability	TGCATTCCTCTGATCCTACCAGG	HERC4	ENSG00000148634	0.489290107454812	[]	[]	6	hSpCas9	negative selection	2773660
68073071	68073094	10	-	27260157	MKN45	viability	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	-0.0561052864612819	[]	[]	0	hSpCas9	negative selection	2796255
68072979	68073002	10	+	27260157	MKN45	viability	TGAGTCCACATCCTACATCTCGG	HERC4	ENSG00000148634	-0.0361137235357963	[]	[]	0	hSpCas9	negative selection	2798568
68072909	68072932	10	-	27260157	MKN45	viability	TGTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	-0.358456983581255	[]	[]	-1	hSpCas9	negative selection	2798828
68072933	68072956	10	-	27260157	MKN45	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.366432877695151	[]	[]	-1	hSpCas9	negative selection	2800489
68073064	68073087	10	+	27260157	RKO	viability	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	0.341057247174445	[]	[]	1	hSpCas9	negative selection	2803283
68044423	68044446	10	-	27260157	RKO	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.109890884625549	[]	[]	0	hSpCas9	negative selection	2804579
68072984	68073007	10	-	27260157	RKO	viability	AGGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.275875908352672	[]	[]	1	hSpCas9	negative selection	2805666
68034087	68034110	10	+	27260157	RKO	viability	AGCAAAGACTTAAGCAGCTGCGG	HERC4	ENSG00000148634	-0.0795851807351443	[]	[]	0	hSpCas9	negative selection	2811352
68072958	68072981	10	-	27260157	RKO	viability	CAGACATACTGTGTTTGTTCTGG	HERC4	ENSG00000148634	-1.09660740617192	[]	[]	-8	hSpCas9	negative selection	2814086
68072918	68072941	10	-	27260157	RKO	viability	ACATGTGGATGTAATGATCTAGG	HERC4	ENSG00000148634	0.580792030949141	[]	[]	3	hSpCas9	negative selection	2833640
68038122	68038145	10	-	27260157	RKO	viability	CAGATTGTACAGGTTGCTTGTGG	HERC4	ENSG00000148634	0.197396494026459	[]	[]	1	hSpCas9	negative selection	2837005
68044435	68044458	10	-	27260157	RKO	viability	TTCTGATGGACAGCTTGGCCTGG	HERC4	ENSG00000148634	1.09811494787263	[]	[]	9	hSpCas9	negative selection	2837197
68073096	68073119	10	-	27260157	RKO	viability	AATTACAAGCATGTTGTGCTGGG	HERC4	ENSG00000148634	1.37258549672525	[]	[]	9	hSpCas9	negative selection	2837846
68044546	68044569	10	-	27260157	RKO	viability	TGTAGAGCAGGTTGTTGCCCTGG	HERC4	ENSG00000148634	0.180000552101988	[]	[]	1	hSpCas9	negative selection	2840200
68072951	68072974	10	-	27260157	RKO	viability	ACTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	-1.11369606824334	[]	[]	-8	hSpCas9	negative selection	2847282
68038123	68038146	10	+	27260157	RKO	viability	CACAAGCAACCTGTACAATCTGG	HERC4	ENSG00000148634	0.115466600783457	[]	[]	0	hSpCas9	negative selection	2847756
68044477	68044500	10	-	27260157	RKO	viability	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.434504528495559	[]	[]	2	hSpCas9	negative selection	2847806
68073062	68073085	10	-	27260157	RKO	viability	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	-0.190529717343522	[]	[]	-1	hSpCas9	negative selection	2848022
68044417	68044440	10	+	27260157	RKO	viability	TGCATTCCTCTGATCCTACCAGG	HERC4	ENSG00000148634	0.560747614468802	[]	[]	3	hSpCas9	negative selection	2849790
68073071	68073094	10	-	27260157	RKO	viability	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.644299209155596	[]	[]	3	hSpCas9	negative selection	2872385
68072979	68073002	10	+	27260157	RKO	viability	TGAGTCCACATCCTACATCTCGG	HERC4	ENSG00000148634	0.260074121155876	[]	[]	1	hSpCas9	negative selection	2874698
68072909	68072932	10	-	27260157	RKO	viability	TGTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.412959678081119	[]	[]	2	hSpCas9	negative selection	2874958
68072933	68072956	10	-	27260157	RKO	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.0524237534546765	[]	[]	0	hSpCas9	negative selection	2876619
68073064	68073087	10	+	27260157	SF268	viability	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	0.408418708885666	[]	[]	4	hSpCas9	negative selection	2879413
68044423	68044446	10	-	27260157	SF268	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-0.274003663078959	[]	[]	-2	hSpCas9	negative selection	2880709
68072984	68073007	10	-	27260157	SF268	viability	AGGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	-0.0756562795662761	[]	[]	0	hSpCas9	negative selection	2881796
68034087	68034110	10	+	27260157	SF268	viability	AGCAAAGACTTAAGCAGCTGCGG	HERC4	ENSG00000148634	-0.523380254289518	[]	[]	-4	hSpCas9	negative selection	2887482
68072958	68072981	10	-	27260157	SF268	viability	CAGACATACTGTGTTTGTTCTGG	HERC4	ENSG00000148634	-0.792603217781429	[]	[]	-6	hSpCas9	negative selection	2890216
68072918	68072941	10	-	27260157	SF268	viability	ACATGTGGATGTAATGATCTAGG	HERC4	ENSG00000148634	-0.736411218003321	[]	[]	-5	hSpCas9	negative selection	2909770
68038122	68038145	10	-	27260157	SF268	viability	CAGATTGTACAGGTTGCTTGTGG	HERC4	ENSG00000148634	-0.246039068560596	[]	[]	-2	hSpCas9	negative selection	2913135
68044435	68044458	10	-	27260157	SF268	viability	TTCTGATGGACAGCTTGGCCTGG	HERC4	ENSG00000148634	0.0453799236179169	[]	[]	0	hSpCas9	negative selection	2913327
68073096	68073119	10	-	27260157	SF268	viability	AATTACAAGCATGTTGTGCTGGG	HERC4	ENSG00000148634	0.426521443568096	[]	[]	4	hSpCas9	negative selection	2913976
68044546	68044569	10	-	27260157	SF268	viability	TGTAGAGCAGGTTGTTGCCCTGG	HERC4	ENSG00000148634	0.0729826317651354	[]	[]	0	hSpCas9	negative selection	2916330
68072951	68072974	10	-	27260157	SF268	viability	ACTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.568968886461772	[]	[]	8	hSpCas9	negative selection	2923412
68038123	68038146	10	+	27260157	SF268	viability	CACAAGCAACCTGTACAATCTGG	HERC4	ENSG00000148634	-0.629513041849845	[]	[]	-5	hSpCas9	negative selection	2923886
68044477	68044500	10	-	27260157	SF268	viability	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.0935620199153598	[]	[]	0	hSpCas9	negative selection	2923936
68073062	68073085	10	-	27260157	SF268	viability	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	-0.604677242688614	[]	[]	-5	hSpCas9	negative selection	2924152
68044417	68044440	10	+	27260157	SF268	viability	TGCATTCCTCTGATCCTACCAGG	HERC4	ENSG00000148634	0.216262265959434	[]	[]	3	hSpCas9	negative selection	2925920
68073071	68073094	10	-	27260157	SF268	viability	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.389837885515423	[]	[]	4	hSpCas9	negative selection	2948515
68072979	68073002	10	+	27260157	SF268	viability	TGAGTCCACATCCTACATCTCGG	HERC4	ENSG00000148634	0.653877979640797	[]	[]	8	hSpCas9	negative selection	2950828
68072909	68072932	10	-	27260157	SF268	viability	TGTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.0949891099502152	[]	[]	0	hSpCas9	negative selection	2951088
68072933	68072956	10	-	27260157	SF268	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.469606133148087	[]	[]	-4	hSpCas9	negative selection	2952749
68073065	68073088	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	0.2146013687203971	[4,4]	[4,4]	4	hSpCas9	positive selection	2993066
68073095	68073118	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTACAAGCATGTTGTGCTGGGG	HERC4	ENSG00000148634	-0.10370446286053131	[3,3]	[3,1]	-1	hSpCas9	positive selection	2993067
68073079	68073102	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGGGAAATGCATCCTTTGGG	HERC4	ENSG00000148634	-0.4084430436190709	[3,3]	[3,1]	-5	hSpCas9	positive selection	2993068
68073062	68073085	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	0.07505806867576359	[4,5]	[5,3]	1	hSpCas9	positive selection	2993069
68073065	68073088	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	-0.08789049048375497	[4,4]	[3,2]	-1	hSpCas9	positive selection	3060924
68073095	68073118	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTACAAGCATGTTGTGCTGGGG	HERC4	ENSG00000148634	0.10516974879938137	[3,3]	[4,0]	1	hSpCas9	positive selection	3060925
68073079	68073102	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGGGAAATGCATCCTTTGGG	HERC4	ENSG00000148634	-0.13544109456585313	[3,3]	[3,0]	-2	hSpCas9	positive selection	3060926
68073062	68073085	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	0.1228322761939486	[4,4]	[5,2]	2	hSpCas9	positive selection	3060927
68073071	68073094		-	24336571	A375	resistance to PLX after 7 days	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	-0.20120641086301294	[37,36]	[29,34]	-6	hSpCas9	positive selection	3118811
68025631	68025654		-	24336571	A375	resistance to PLX after 7 days	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.0019309381617885757	[15,14]	[14,14]	0	hSpCas9	positive selection	3118812
68072875	68072898		+	24336571	A375	resistance to PLX after 7 days	CAACTTACCTGGTTTCTTTCTGG	HERC4	ENSG00000148634	-0.04153324712657147	[20,16]	[19,16]	-1	hSpCas9	positive selection	3118814
68025596	68025619		-	24336571	A375	resistance to PLX after 7 days	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.48700100480692965	[8,9]	[4,7]	-9	hSpCas9	positive selection	3118815
68073071	68073094		-	24336571	A375	resistance to PLX after 14 days	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.6131713847898066	[48,36]	[33,26]	5	hSpCas9	positive selection	3176604
68025631	68025654		-	24336571	A375	resistance to PLX after 14 days	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.5854936103435896	[22,15]	[4,5]	-7	hSpCas9	positive selection	3176605
68072875	68072898		+	24336571	A375	resistance to PLX after 14 days	CAACTTACCTGGTTTCTTTCTGG	HERC4	ENSG00000148634	-0.3541859157444476	[18,15]	[6,4]	-4	hSpCas9	positive selection	3176607
68025596	68025619		-	24336571	A375	resistance to PLX after 14 days	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.46804035442169634	[4,7]	[1,1]	-5	hSpCas9	positive selection	3176608
68073071	68073094		-	24336571	A375	viability after 7 days	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.22522138450792406	[33]	[37,36]	3	hSpCas9	negative selection	3234397
68025631	68025654		-	24336571	A375	viability after 7 days	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.686110021897597	[9]	[15,14]	8	hSpCas9	negative selection	3234398
68072875	68072898		+	24336571	A375	viability after 7 days	CAACTTACCTGGTTTCTTTCTGG	HERC4	ENSG00000148634	0.13014044156527643	[17]	[20,16]	2	hSpCas9	negative selection	3234400
68025596	68025619		-	24336571	A375	viability after 7 days	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.8120991011551975	[17]	[8,9]	-8	hSpCas9	negative selection	3234401
68073071	68073094		-	24336571	A375	viability after 14 days	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.4345404342902375	[33]	[48,36]	5	hSpCas9	negative selection	3292190
68025631	68025654		-	24336571	A375	viability after 14 days	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	1.0159803618577246	[9]	[22,15]	9	hSpCas9	negative selection	3292191
68072875	68072898		+	24336571	A375	viability after 14 days	CAACTTACCTGGTTTCTTTCTGG	HERC4	ENSG00000148634	0.029537011114730505	[17]	[18,15]	0	hSpCas9	negative selection	3292193
68025596	68025619		-	24336571	A375	viability after 14 days	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-1.2806117931530698	[17]	[4,7]	-9	hSpCas9	negative selection	3292194
68014025	68014048	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	-0.4839204455300469	[208,218]	[0,0]	-3	hSpCas9	positive selection	3353257
68014142	68014165	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.9021910711685537	[60,102]	[0,0]	4	hSpCas9	positive selection	3353258
68025549	68025572	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	-0.2061714494552381	[175,176]	[0,0]	-1	hSpCas9	positive selection	3353259
68072933	68072956	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	1.2800462879459185	[62,62]	[0,0]	5	hSpCas9	positive selection	3372451
68073097	68073120	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-1.670451750636507	[486,486]	[0,0]	-9	hSpCas9	positive selection	3372452
68025631	68025654	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.7027373597681978	[93,93]	[0,0]	3	hSpCas9	positive selection	3372453
68073064	68073087	10	+	26780180	HT29	viability (Avana library 4 designs)	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	-1.1049436222438	[]	[]	-9	hSpCas9	negative selection	3430327
68073095	68073118	10	-	26780180	HT29	viability (Avana library 4 designs)	ATTACAAGCATGTTGTGCTGGGG	HERC4	ENSG00000148634	1.43735248957634	[]	[]	5	hSpCas9	negative selection	3430328
68073079	68073102	10	-	26780180	HT29	viability (Avana library 4 designs)	GCTGGGGAAATGCATCCTTTGGG	HERC4	ENSG00000148634	2.18242374371654	[]	[]	7	hSpCas9	negative selection	3430329
68073062	68073085	10	-	26780180	HT29	viability (Avana library 4 designs)	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	-0.309532436086083	[]	[]	-5	hSpCas9	negative selection	3430330
68073079	68073102	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGGAAATGCATCCTTTGGG	HERC4	ENSG00000148634	4.49278530884731	[]	[]	7	hSpCas9	negative selection	3515433
68073064	68073087	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	0.0260466326477076	[]	[]	0	hSpCas9	negative selection	3515434
68073095	68073118	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATTACAAGCATGTTGTGCTGGGG	HERC4	ENSG00000148634	2.43159089442209	[]	[]	3	hSpCas9	negative selection	3515435
68073062	68073085	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	6.18677299912568	[]	[]	9	hSpCas9	negative selection	3515436
68073003	68073026	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-13.542044473093	[]	[]	-8	hSpCas9	negative selection	3515437
68073071	68073094	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	2.49858605029205	[]	[]	4	hSpCas9	negative selection	3515438
68073079	68073102	10	-	26780180	A375	viability (Avana lentiGuide)	GCTGGGGAAATGCATCCTTTGGG	HERC4	ENSG00000148634	-1.09236939429258	[]	[]	-2	hSpCas9	negative selection	3624092
68073064	68073087	10	+	26780180	A375	viability (Avana lentiGuide)	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	-4.27888378128953	[]	[]	-7	hSpCas9	negative selection	3624093
68073095	68073118	10	-	26780180	A375	viability (Avana lentiGuide)	ATTACAAGCATGTTGTGCTGGGG	HERC4	ENSG00000148634	1.39641182647595	[]	[]	1	hSpCas9	negative selection	3624094
68073062	68073085	10	-	26780180	A375	viability (Avana lentiGuide)	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	-2.1771894537144	[]	[]	-4	hSpCas9	negative selection	3624095
68073003	68073026	10	-	26780180	A375	viability (Avana lentiGuide)	TGACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-4.35775888599493	[]	[]	-7	hSpCas9	negative selection	3624096
68073071	68073094	10	-	26780180	A375	viability (Avana lentiGuide)	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	-3.82284640875257	[]	[]	-6	hSpCas9	negative selection	3624097
68073079	68073102	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGGAAATGCATCCTTTGGG	HERC4	ENSG00000148634	0.18569407381239267	[4]	[5,5]	5	hSpCas9	positive selection	3732751
68073064	68073087	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	-0.06900647481944684	[5]	[5,4]	-1	hSpCas9	positive selection	3732752
68073095	68073118	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTACAAGCATGTTGTGCTGGGG	HERC4	ENSG00000148634	-0.20385861510141287	[5]	[5,3]	-3	hSpCas9	positive selection	3732753
68073062	68073085	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	0.32596877264568824	[5]	[7,6]	8	hSpCas9	positive selection	3732754
68073003	68073026	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-1.1377563389127725	[10]	[4,3]	-9	hSpCas9	positive selection	3732755
68073071	68073094	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.18414076804624638	[5]	[5,5]	5	hSpCas9	positive selection	3732756
68073079	68073102	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGGAAATGCATCCTTTGGG	HERC4	ENSG00000148634	-0.04123075117391179	[5]	[4,4]	0	hSpCas9	positive selection	3841358
68073064	68073087	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCCAAACCTAGCTGCCCAAAGG	HERC4	ENSG00000148634	0.03888927149990634	[6]	[5,4]	0	hSpCas9	positive selection	3841359
68073095	68073118	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTACAAGCATGTTGTGCTGGGG	HERC4	ENSG00000148634	-0.27550975373116626	[5]	[2,4]	-4	hSpCas9	positive selection	3841360
68073062	68073085	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGGGCAGCTAGGTTTGGGTGG	HERC4	ENSG00000148634	0.3062990877983549	[6]	[6,7]	8	hSpCas9	positive selection	3841361
68073003	68073026	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	0.3390476380396533	[5]	[6,6]	8	hSpCas9	positive selection	3841362
68073071	68073094	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.37553542077136015	[5]	[6,6]	9	hSpCas9	positive selection	3841363
68025631	68025654	10	-	26780180	A375	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	1.21318001576949	[]	[]	6	hSpCas9	negative selection	3947425
68025549	68025572	10	-	26780180	A375	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.552009039846138	[]	[]	1	hSpCas9	negative selection	3947426
68014142	68014165	10	+	26780180	A375	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.939513808338459	[]	[]	4	hSpCas9	negative selection	3947427
68072933	68072956	10	-	26780180	A375	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.760564975137024	[]	[]	3	hSpCas9	negative selection	3947428
68014025	68014048	10	-	26780180	A375	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	1.77548863521591	[]	[]	9	hSpCas9	negative selection	3947429
68073097	68073120	10	-	26780180	A375	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	1.19850059089632	[]	[]	6	hSpCas9	negative selection	3947430
68025631	68025654	10	-	26780180	HT29	viability (GeCKOv2 library)	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	1.2940216272733	[]	[]	6	hSpCas9	negative selection	4055391
68025549	68025572	10	-	26780180	HT29	viability (GeCKOv2 library)	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.165690570759042	[]	[]	0	hSpCas9	negative selection	4055392
68014142	68014165	10	+	26780180	HT29	viability (GeCKOv2 library)	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	1.30492204988382	[]	[]	6	hSpCas9	negative selection	4055393
68072933	68072956	10	-	26780180	HT29	viability (GeCKOv2 library)	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	1.14429145307535	[]	[]	5	hSpCas9	negative selection	4055394
68014025	68014048	10	-	26780180	HT29	viability (GeCKOv2 library)	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	1.56934004189497	[]	[]	8	hSpCas9	negative selection	4055395
68073097	68073120	10	-	26780180	HT29	viability (GeCKOv2 library)	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	1.29913231711233	[]	[]	6	hSpCas9	negative selection	4055396
68073071	68073094	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.26015430182377997	[5]	[3,4]	6	hSpCas9	positive selection	4142272
68025631	68025654	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.1606365993436456	[4]	[2,2]	-4	hSpCas9	positive selection	4142273
68072875	68072898	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAACTTACCTGGTTTCTTTCTGG	HERC4	ENSG00000148634	0.012557595734264237	[4]	[3,2]	0	hSpCas9	positive selection	4142276
68025596	68025619	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.7261427601202601	[3]	[1,0]	-9	hSpCas9	positive selection	4142277
68073071	68073094	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATGCATCCTTTGGGCAGCTAGG	HERC4	ENSG00000148634	0.02548733842651174	[5]	[3,3,3,0]	0	hSpCas9	positive selection	4206294
68025631	68025654	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.5474082102354323	[4]	[2,0,0,0]	-7	hSpCas9	positive selection	4206295
68072875	68072898	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAACTTACCTGGTTTCTTTCTGG	HERC4	ENSG00000148634	1.3017757147731295	[3]	[4,0,2,5]	9	hSpCas9	positive selection	4206298
68025596	68025619	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.537535643911389	[3]	[3,3,4,0]	3	hSpCas9	positive selection	4206299
68014025	68014048	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	-0.6673122940504258	[3]	[1,0]	-9	hSpCas9	positive selection	4274841
68014142	68014165	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.46272389543637726	[2]	[1,0]	-7	hSpCas9	positive selection	4274842
68025549	68025572	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.04201535919085847	[2]	[3,1]	0	hSpCas9	positive selection	4274843
68072933	68072956	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.41318623205610117	[1]	[1,0]	-7	hSpCas9	positive selection	4339102
68073097	68073120	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.19999175399865404	[4]	[3,4]	4	hSpCas9	positive selection	4339103
68025631	68025654	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.026692648359533333	[1]	[2,0]	0	hSpCas9	positive selection	4339104
68014090	68014112	10	-	27760321	OCIAML3	viability	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.7602061700931998	[314,246]	[321,431]	8	hSpCas9	negative selection	4406650
68034128	68034150	10	+	27760321	OCIAML3	viability	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	-1.1827601048436165	[110,82]	[33,31]	-8	hSpCas9	negative selection	4406651
68044482	68044504	10	-	27760321	OCIAML3	viability	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	0.06576184906359739	[76,48]	[32,73]	0	hSpCas9	negative selection	4406652
68072909	68072931	10	-	27760321	OCIAML3	viability	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.5164638266721916	[231,239]	[233,305]	6	hSpCas9	negative selection	4406653
68072933	68072955	10	-	27760321	OCIAML3	viability	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.5868051293893184	[91,68]	[78,112]	7	hSpCas9	negative selection	4406654
68072951	68072973	10	-	27760321	OCIAML3	viability	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.03209147066607326	[362,328]	[305,237]	0	hSpCas9	negative selection	4406655
68072984	68073006	10	-	27760321	OCIAML3	viability	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	-0.027059294685016944	[412,324]	[194,393]	0	hSpCas9	negative selection	4406656
68073003	68073025	10	-	27760321	OCIAML3	viability	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	0.349869932207314	[0,0]	[0,0]	4	hSpCas9	negative selection	4406657
68014090	68014112	10	-	27760321	OCIAML2	viability	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.10591344534944758	[314,246]	[220,271]	1	hSpCas9	negative selection	4490113
68034128	68034150	10	+	27760321	OCIAML2	viability	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	0.00987859751834641	[110,82]	[29,141]	0	hSpCas9	negative selection	4490114
68044482	68044504	10	-	27760321	OCIAML2	viability	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	-0.4568276272188778	[76,48]	[14,64]	-5	hSpCas9	negative selection	4490115
68072909	68072931	10	-	27760321	OCIAML2	viability	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.15484085157445449	[231,239]	[134,316]	2	hSpCas9	negative selection	4490116
68072933	68072955	10	-	27760321	OCIAML2	viability	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.27801069071114126	[91,68]	[76,79]	3	hSpCas9	negative selection	4490117
68072951	68072973	10	-	27760321	OCIAML2	viability	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.12300899556957354	[362,328]	[260,361]	1	hSpCas9	negative selection	4490118
68072984	68073006	10	-	27760321	OCIAML2	viability	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.9459771440067133	[412,324]	[522,634]	9	hSpCas9	negative selection	4490119
68073003	68073025	10	-	27760321	OCIAML2	viability	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	0.3011245669422653	[0,0]	[0,0]	4	hSpCas9	negative selection	4490120
68014090	68014112	10	-	27760321	MV411	viability	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-0.9284710430036153	[314,246]	[73,130]	-6	hSpCas9	negative selection	4573576
68034128	68034150	10	+	27760321	MV411	viability	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	1.432500428916954	[110,82]	[283,1]	9	hSpCas9	negative selection	4573577
68044482	68044504	10	-	27760321	MV411	viability	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	-1.5272990297676703	[76,48]	[22,0]	-7	hSpCas9	negative selection	4573578
68072909	68072931	10	-	27760321	MV411	viability	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	1.3830833235899305	[231,239]	[527,227]	8	hSpCas9	negative selection	4573579
68072933	68072955	10	-	27760321	MV411	viability	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	2.1468833021897242	[91,68]	[323,96]	9	hSpCas9	negative selection	4573580
68072951	68072973	10	-	27760321	MV411	viability	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.043014965590562226	[362,328]	[65,488]	0	hSpCas9	negative selection	4573581
68072984	68073006	10	-	27760321	MV411	viability	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.6860413607367136	[412,324]	[407,360]	5	hSpCas9	negative selection	4573582
68073003	68073025	10	-	27760321	MV411	viability	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	0.5949485011219959	[0,0]	[0,0]	4	hSpCas9	negative selection	4573583
68014090	68014112	10	-	27760321	HL60	viability	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.1688199337961594	[314,246]	[266,244]	2	hSpCas9	negative selection	4657039
68034128	68034150	10	+	27760321	HL60	viability	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	-2.1071129290203747	[110,82]	[25,9]	-9	hSpCas9	negative selection	4657040
68044482	68044504	10	-	27760321	HL60	viability	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	1.3287053500689487	[76,48]	[187,62]	9	hSpCas9	negative selection	4657041
68072909	68072931	10	-	27760321	HL60	viability	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.37027121592255197	[231,239]	[228,272]	4	hSpCas9	negative selection	4657042
68072933	68072955	10	-	27760321	HL60	viability	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.5666747559405714	[91,68]	[98,93]	6	hSpCas9	negative selection	4657043
68072951	68072973	10	-	27760321	HL60	viability	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.005221430832804075	[362,328]	[314,249]	0	hSpCas9	negative selection	4657044
68072984	68073006	10	-	27760321	HL60	viability	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	-0.5992472577298926	[412,324]	[186,208]	-6	hSpCas9	negative selection	4657045
68073003	68073025	10	-	27760321	HL60	viability	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	0.2870783393278593	[0,0]	[0,0]	3	hSpCas9	negative selection	4657046
68014090	68014112	10	-	27760321	HT1080	viability	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.5410414590727639	[246,192]	[85,172]	3	hSpCas9	negative selection	4740502
68034128	68034150	10	+	27760321	HT1080	viability	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	-1.8216406818591366	[82,64]	[4,11]	-6	hSpCas9	negative selection	4740503
68044482	68044504	10	-	27760321	HT1080	viability	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	-4.114558017842154	[48,37]	[0,0]	-8	hSpCas9	negative selection	4740504
68072909	68072931	10	-	27760321	HT1080	viability	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	-0.1392331738182554	[239,186]	[123,25]	0	hSpCas9	negative selection	4740505
68072933	68072955	10	-	27760321	HT1080	viability	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-1.5043069415497232	[68,53]	[0,16]	-5	hSpCas9	negative selection	4740506
68072951	68072973	10	-	27760321	HT1080	viability	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.31386057637816117	[328,256]	[104,188]	1	hSpCas9	negative selection	4740507
68072984	68073006	10	-	27760321	HT1080	viability	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	-0.12227924152931147	[324,253]	[41,175]	0	hSpCas9	negative selection	4740508
68073003	68073025	10	-	27760321	HT1080	viability	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	1.3056276939190559	[0,0]	[0,0]	7	hSpCas9	negative selection	4740509
68014090	68014112	10	-	27760321	HT29	viability after 7 days	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.5563656139667094	[246,192]	[387,522,334]	8	hSpCas9	negative selection	4823965
68034128	68034150	10	+	27760321	HT29	viability after 7 days	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	0.8859024859196956	[82,64]	[234,164,136]	9	hSpCas9	negative selection	4823966
68044482	68044504	10	-	27760321	HT29	viability after 7 days	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	-0.5530915010039879	[48,37]	[28,78,5]	-7	hSpCas9	negative selection	4823967
68072909	68072931	10	-	27760321	HT29	viability after 7 days	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	-0.006430192443357852	[239,186]	[269,437,115]	0	hSpCas9	negative selection	4823968
68072933	68072955	10	-	27760321	HT29	viability after 7 days	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.6705537912934585	[68,53]	[235,89,68]	8	hSpCas9	negative selection	4823969
68072951	68072973	10	-	27760321	HT29	viability after 7 days	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	-0.2356950270899521	[328,256]	[484,243,255]	-3	hSpCas9	negative selection	4823970
68072984	68073006	10	-	27760321	HT29	viability after 7 days	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.5924942902624126	[324,253]	[425,365,861]	8	hSpCas9	negative selection	4823971
68073003	68073025	10	-	27760321	HT29	viability after 7 days	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-0.3840325596302083	[0,0]	[0,0,0]	-5	hSpCas9	negative selection	4823972
68014090	68014112	10	-	27760321	HT29	viability after 25 days	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.5012530663421596	[246,192]	[309,326,441]	5	hSpCas9	negative selection	4907428
68034128	68034150	10	+	27760321	HT29	viability after 25 days	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	0.6358390526188498	[82,64]	[84,154,159]	7	hSpCas9	negative selection	4907429
68044482	68044504	10	-	27760321	HT29	viability after 25 days	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	0.4612921171241826	[48,37]	[44,20,148]	5	hSpCas9	negative selection	4907430
68072909	68072931	10	-	27760321	HT29	viability after 25 days	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.5919852542300698	[239,186]	[175,516,427]	6	hSpCas9	negative selection	4907431
68072933	68072955	10	-	27760321	HT29	viability after 25 days	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	1.326050011863791	[68,53]	[268,142,102]	9	hSpCas9	negative selection	4907432
68072951	68072973	10	-	27760321	HT29	viability after 25 days	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.27497466899720685	[328,256]	[219,571,437]	3	hSpCas9	negative selection	4907433
68072984	68073006	10	-	27760321	HT29	viability after 25 days	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.9900636873090146	[324,253]	[545,710,727]	9	hSpCas9	negative selection	4907434
68073003	68073025	10	-	27760321	HT29	viability after 25 days	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-0.21405457092746794	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4907435
68014090	68014112	10	-	27760321	HT29	viability after 22 days	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.41952520041818564	[246,192]	[489,238,286]	4	hSpCas9	negative selection	4990891
68034128	68034150	10	+	27760321	HT29	viability after 22 days	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	0.6227735374190024	[82,64]	[134,146,112]	7	hSpCas9	negative selection	4990892
68044482	68044504	10	-	27760321	HT29	viability after 22 days	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	0.33084731308745674	[48,37]	[93,14,79]	3	hSpCas9	negative selection	4990893
68072909	68072931	10	-	27760321	HT29	viability after 22 days	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.34057497505184137	[239,186]	[200,479,258]	3	hSpCas9	negative selection	4990894
68072933	68072955	10	-	27760321	HT29	viability after 22 days	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	1.555678767881027	[68,53]	[419,139,59]	9	hSpCas9	negative selection	4990895
68072951	68072973	10	-	27760321	HT29	viability after 22 days	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.21179680619198832	[328,256]	[221,410,549]	2	hSpCas9	negative selection	4990896
68072984	68073006	10	-	27760321	HT29	viability after 22 days	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.49743788097238617	[324,253]	[259,610,552]	5	hSpCas9	negative selection	4990897
68073003	68073025	10	-	27760321	HT29	viability after 22 days	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-0.23137320278672746	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	4990898
68014090	68014112	10	-	27760321	HT29	viability after 19 days	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.6613708373538978	[246,192]	[412,458,325]	6	hSpCas9	negative selection	5074354
68034128	68034150	10	+	27760321	HT29	viability after 19 days	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	0.1658767745461538	[82,64]	[48,81,146]	1	hSpCas9	negative selection	5074355
68044482	68044504	10	-	27760321	HT29	viability after 19 days	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	0.5164230891819073	[48,37]	[176,44,4]	5	hSpCas9	negative selection	5074356
68072909	68072931	10	-	27760321	HT29	viability after 19 days	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.24576848697521947	[239,186]	[245,254,359]	2	hSpCas9	negative selection	5074357
68072933	68072955	10	-	27760321	HT29	viability after 19 days	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.9430734496700324	[68,53]	[224,79,110]	8	hSpCas9	negative selection	5074358
68072951	68072973	10	-	27760321	HT29	viability after 19 days	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.594791702580394	[328,256]	[487,465,559]	6	hSpCas9	negative selection	5074359
68072984	68073006	10	-	27760321	HT29	viability after 19 days	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.1362611461517634	[324,253]	[452,314,333]	1	hSpCas9	negative selection	5074360
68073003	68073025	10	-	27760321	HT29	viability after 19 days	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-0.21553315036351428	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5074361
68014090	68014112	10	-	27760321	HT29	viability after 16 days	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.3959914845749556	[246,192]	[509,217,263]	4	hSpCas9	negative selection	5157817
68034128	68034150	10	+	27760321	HT29	viability after 16 days	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	1.2498216539703195	[82,64]	[283,157,157]	9	hSpCas9	negative selection	5157818
68044482	68044504	10	-	27760321	HT29	viability after 16 days	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	0.1609639889320369	[48,37]	[16,1,141]	1	hSpCas9	negative selection	5157819
68072909	68072931	10	-	27760321	HT29	viability after 16 days	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.5639915549311818	[239,186]	[205,326,512]	6	hSpCas9	negative selection	5157820
68072933	68072955	10	-	27760321	HT29	viability after 16 days	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.7589609586677577	[68,53]	[141,145,62]	8	hSpCas9	negative selection	5157821
68072951	68072973	10	-	27760321	HT29	viability after 16 days	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.27403370496621715	[328,256]	[558,300,346]	3	hSpCas9	negative selection	5157822
68072984	68073006	10	-	27760321	HT29	viability after 16 days	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.5630017923949973	[324,253]	[469,506,456]	6	hSpCas9	negative selection	5157823
68073003	68073025	10	-	27760321	HT29	viability after 16 days	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-0.1840686979425925	[0,0]	[0,0,0]	-2	hSpCas9	negative selection	5157824
68014090	68014112	10	-	27760321	HT29	viability after 13 days	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.46624431892528473	[246,192]	[434,327,297]	6	hSpCas9	negative selection	5241280
68034128	68034150	10	+	27760321	HT29	viability after 13 days	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	0.18655001902045987	[82,64]	[44,111,133]	2	hSpCas9	negative selection	5241281
68044482	68044504	10	-	27760321	HT29	viability after 13 days	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	-1.4225870468950506	[48,37]	[19,9,25]	-8	hSpCas9	negative selection	5241282
68072909	68072931	10	-	27760321	HT29	viability after 13 days	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	0.6195665018564295	[239,186]	[185,508,442]	7	hSpCas9	negative selection	5241283
68072933	68072955	10	-	27760321	HT29	viability after 13 days	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.0044969272434358665	[68,53]	[81,87,44]	0	hSpCas9	negative selection	5241284
68072951	68072973	10	-	27760321	HT29	viability after 13 days	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.05684967786846473	[328,256]	[501,351,214]	0	hSpCas9	negative selection	5241285
68072984	68073006	10	-	27760321	HT29	viability after 13 days	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.49562263153435276	[324,253]	[360,383,663]	6	hSpCas9	negative selection	5241286
68073003	68073025	10	-	27760321	HT29	viability after 13 days	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-0.23635609738673047	[0,0]	[0,0,0]	-3	hSpCas9	negative selection	5241287
68014090	68014112	10	-	27760321	HT29	viability after 10 days	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.5406978889087523	[246,192]	[351,385,458]	7	hSpCas9	negative selection	5324743
68034128	68034150	10	+	27760321	HT29	viability after 10 days	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	1.0014928875603617	[82,64]	[190,201,162]	9	hSpCas9	negative selection	5324744
68044482	68044504	10	-	27760321	HT29	viability after 10 days	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	0.9239145172158127	[48,37]	[44,88,172]	9	hSpCas9	negative selection	5324745
68072909	68072931	10	-	27760321	HT29	viability after 10 days	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	-0.13033135275808605	[239,186]	[181,320,229]	-2	hSpCas9	negative selection	5324746
68072933	68072955	10	-	27760321	HT29	viability after 10 days	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.49327707561306555	[68,53]	[134,49,136]	6	hSpCas9	negative selection	5324747
68072951	68072973	10	-	27760321	HT29	viability after 10 days	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	0.007668015547595997	[328,256]	[432,311,356]	0	hSpCas9	negative selection	5324748
68072984	68073006	10	-	27760321	HT29	viability after 10 days	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.2629904015085338	[324,253]	[616,386,298]	3	hSpCas9	negative selection	5324749
68073003	68073025	10	-	27760321	HT29	viability after 10 days	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	-0.34236740454707437	[0,0]	[0,0,0]	-4	hSpCas9	negative selection	5324750
68014090	68014112	10	-	27760321	MOLM13	viability	AACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.78954507335331	[314,246]	[80,434]	5	hSpCas9	negative selection	5408206
68034128	68034150	10	+	27760321	MOLM13	viability	GTCAGTACCTAAACCCAATTGG	HERC4	ENSG00000148634	0.3616246607832574	[110,82]	[86,54]	2	hSpCas9	negative selection	5408207
68044482	68044504	10	-	27760321	MOLM13	viability	CGTTAGCGCTAAATGACAAAGG	HERC4	ENSG00000148634	-1.2341571642299494	[76,48]	[2,24]	-6	hSpCas9	negative selection	5408208
68072909	68072931	10	-	27760321	MOLM13	viability	GTAATGATCTAGGACAGCTAGG	HERC4	ENSG00000148634	1.1013506712449825	[231,239]	[232,332]	7	hSpCas9	negative selection	5408209
68072933	68072955	10	-	27760321	MOLM13	viability	ATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.7026632365627346	[91,68]	[58,0]	-4	hSpCas9	negative selection	5408210
68072951	68072973	10	-	27760321	MOLM13	viability	CTGTGTTTGTTCTGGATGATGG	HERC4	ENSG00000148634	-1.265388837690148	[362,328]	[132,36]	-6	hSpCas9	negative selection	5408211
68072984	68073006	10	-	27760321	MOLM13	viability	GGGTCCGAGATGTAGGATGTGG	HERC4	ENSG00000148634	0.7290191677023322	[412,324]	[176,483]	5	hSpCas9	negative selection	5408212
68073003	68073025	10	-	27760321	MOLM13	viability	GACTTCTTTATAAATAAAAGGG	HERC4	ENSG00000148634	0.8210053139495912	[0,0]	[0,0]	6	hSpCas9	negative selection	5408213
68074964	68074987	10	+	27661255	K562	viability	GGGAAGCCCAAGGTGACGGGGGG	HERC4	ENSG00000148634	0.4061161080235727	[387,380]	[418,396]	9	dCas9-KRAB	negative selection	5484456
68075222	68075245	10	+	27661255	K562	viability	GGAAGAACGGGAGGCAAGCGGGG	HERC4	ENSG00000148634	0.03130208530672457	[518,582]	[531,377]	1	dCas9-KRAB	negative selection	5484457
68075169	68075192	10	-	27661255	K562	viability	GTCTCTGGACTGGACAGCAGTGG	HERC4	ENSG00000148634	0.3465071795950668	[514,576]	[655,465]	9	dCas9-KRAB	negative selection	5484458
68014025	68014048	10	-	27260156	BXPC3	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.2705375387471364	[629]	[683,766,902,839]	6	hSpCas9	negative selection	5547301
68014142	68014165	10	+	27260156	BXPC3	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.10652662603313856	[275]	[223,293,261,296]	-2	hSpCas9	negative selection	5547302
68025549	68025572	10	-	27260156	BXPC3	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.4565457391165146	[435]	[579,673,601,645]	8	hSpCas9	negative selection	5547303
68072933	68072956	10	-	27260156	BXPC3	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.18331337603729714	[163]	[143,103,196,163]	-4	hSpCas9	negative selection	5611562
68073097	68073120	10	-	27260156	BXPC3	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.05762602253279603	[1434]	[1297,1410,1487,1596]	-1	hSpCas9	negative selection	5611563
68025631	68025654	10	-	27260156	BXPC3	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.29780620094234533	[195]	[214,222,305,270]	6	hSpCas9	negative selection	5611564
68014025	68014048	10	-	27260156	A673	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.3372271057197781	[629]	[1036,1021,867,898]	7	hSpCas9	negative selection	5668552
68014142	68014165	10	+	27260156	A673	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.21961676289227683	[275]	[328,346,407,456]	5	hSpCas9	negative selection	5668553
68025549	68025572	10	-	27260156	A673	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.2245618294243519	[435]	[623,596,589,637]	5	hSpCas9	negative selection	5668554
68072933	68072956	10	-	27260156	A673	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.2223349199695821	[163]	[141,130,232,165]	-5	hSpCas9	negative selection	5732813
68073097	68073120	10	-	27260156	A673	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.2278758143317492	[1434]	[1756,1263,1355,1548]	-5	hSpCas9	negative selection	5732814
68025631	68025654	10	-	27260156	A673	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.0067659218893347806	[195]	[232,253,156,304]	0	hSpCas9	negative selection	5732815
68014025	68014048	10	-	27260156	A375	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.5728132215494305	[629]	[1274,1125,907,1072]	8	hSpCas9	negative selection	5789803
68014142	68014165	10	+	27260156	A375	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.38923808787839	[275]	[280,255,310,148]	-5	hSpCas9	negative selection	5789804
68025549	68025572	10	-	27260156	A375	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.3364282019847321	[435]	[645,539,881,503]	5	hSpCas9	negative selection	5789805
68072933	68072956	10	-	27260156	A375	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.5189921382874609	[163]	[174,95,186,77]	-6	hSpCas9	negative selection	5854064
68073097	68073120	10	-	27260156	A375	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.07345525555881083	[1434]	[1744,2017,1705,1629]	1	hSpCas9	negative selection	5854065
68025631	68025654	10	-	27260156	A375	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.3006818107025532	[195]	[338,409,270,141]	4	hSpCas9	negative selection	5854066
68014025	68014048	10	-	27260156	COLO741	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.14359775855862444	[629]	[953,897,823]	3	hSpCas9	negative selection	5911054
68014142	68014165	10	+	27260156	COLO741	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.2140605511748085	[275]	[321,375,512]	4	hSpCas9	negative selection	5911055
68025549	68025572	10	-	27260156	COLO741	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.2109819447583931	[435]	[579,749,600]	4	hSpCas9	negative selection	5911056
68072933	68072956	10	-	27260156	COLO741	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.18899381412906657	[163]	[369,132,224]	4	hSpCas9	negative selection	5975315
68073097	68073120	10	-	27260156	COLO741	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.2610673179725622	[1434]	[1597,1711,1299]	-5	hSpCas9	negative selection	5975316
68025631	68025654	10	-	27260156	COLO741	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.1754708304081143	[195]	[375,258,224]	4	hSpCas9	negative selection	5975317
68014025	68014048	10	-	27260156	CAL120	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.2406707310209506	[629]	[1213,582,1022]	3	hSpCas9	negative selection	6032305
68014142	68014165	10	+	27260156	CAL120	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-1.142213102579499	[275]	[285,79,120]	-9	hSpCas9	negative selection	6032306
68025549	68025572	10	-	27260156	CAL120	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	-0.3437863792875895	[435]	[344,499,424]	-5	hSpCas9	negative selection	6032307
68072933	68072956	10	-	27260156	CAL120	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-1.7589767568242465	[163]	[83,15,83]	-9	hSpCas9	negative selection	6096566
68073097	68073120	10	-	27260156	CAL120	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.21570547095658776	[1434]	[1594,1314,1707]	-3	hSpCas9	negative selection	6096567
68025631	68025654	10	-	27260156	CAL120	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.1854908214651596	[195]	[370,249,225]	2	hSpCas9	negative selection	6096568
68014025	68014048	10	-	27260156	CADOES1	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.3746421738794169	[629]	[892,787,736,614]	6	hSpCas9	negative selection	6153556
68014142	68014165	10	+	27260156	CADOES1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.00983116349029356	[275]	[234,267,309,204]	0	hSpCas9	negative selection	6153557
68025549	68025572	10	-	27260156	CADOES1	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.09660783422764317	[435]	[378,577,364,411]	1	hSpCas9	negative selection	6153558
68072933	68072956	10	-	27260156	CADOES1	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.20933769223429866	[163]	[119,128,139,138]	-4	hSpCas9	negative selection	6217817
68073097	68073120	10	-	27260156	CADOES1	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.05815745456051702	[1434]	[1631,1486,1145,1288]	1	hSpCas9	negative selection	6217818
68025631	68025654	10	-	27260156	CADOES1	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.117272003076343	[195]	[226,195,216,148]	2	hSpCas9	negative selection	6217819
68014025	68014048	10	-	27260156	EWS502	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.13401285191070023	[629]	[542,778,644,997]	2	hSpCas9	negative selection	6274807
68014142	68014165	10	+	27260156	EWS502	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.809251169938723	[275]	[186,1003,414,454]	9	hSpCas9	negative selection	6274808
68025549	68025572	10	-	27260156	EWS502	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.41962469728277707	[435]	[582,567,704,619]	7	hSpCas9	negative selection	6274809
68072933	68072956	10	-	27260156	EWS502	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.4009015295148237	[163]	[214,65,312,339]	7	hSpCas9	negative selection	6339068
68073097	68073120	10	-	27260156	EWS502	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.11495517898847996	[1434]	[1423,1462,1221,1498]	-2	hSpCas9	negative selection	6339069
68025631	68025654	10	-	27260156	EWS502	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.09553995357765421	[195]	[159,177,341,216]	1	hSpCas9	negative selection	6339070
68014025	68014048	10	-	27260156	EW8	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	-0.06588270076574582	[629]	[600,478,447,440]	-1	hSpCas9	negative selection	6396058
68014142	68014165	10	+	27260156	EW8	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.30519066787067844	[275]	[304,216,182,417]	5	hSpCas9	negative selection	6396059
68025549	68025572	10	-	27260156	EW8	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.11193756732502036	[435]	[486,365,279,421]	2	hSpCas9	negative selection	6396060
68072933	68072956	10	-	27260156	EW8	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.3356201104957912	[163]	[119,58,82,163]	-6	hSpCas9	negative selection	6460319
68073097	68073120	10	-	27260156	EW8	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.16987426254193294	[1434]	[1223,1100,865,990]	-3	hSpCas9	negative selection	6460320
68025631	68025654	10	-	27260156	EW8	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.11827294144048861	[195]	[111,153,176,132]	-2	hSpCas9	negative selection	6460321
68014025	68014048	10	-	27260156	CORL105	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.1914859110671845	[629]	[857,764,1014,759]	3	hSpCas9	negative selection	6517309
68014142	68014165	10	+	27260156	CORL105	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.08836892057983436	[275]	[381,308,299,377]	1	hSpCas9	negative selection	6517310
68025549	68025572	10	-	27260156	CORL105	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	-0.09912509270948133	[435]	[467,390,501,549]	-2	hSpCas9	negative selection	6517311
68072933	68072956	10	-	27260156	CORL105	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.200445039036645	[163]	[117,266,142,132]	-4	hSpCas9	negative selection	6581570
68073097	68073120	10	-	27260156	CORL105	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.16139174815471202	[1434]	[1452,1456,1640,1477]	-3	hSpCas9	negative selection	6581571
68025631	68025654	10	-	27260156	CORL105	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.13144280310216527	[195]	[173,137,230,297]	-2	hSpCas9	negative selection	6581572
68014025	68014048	10	-	27260156	HS294T	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.43311708675169047	[629]	[480,268,290,246]	6	hSpCas9	negative selection	6638560
68014142	68014165	10	+	27260156	HS294T	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.3219323446013839	[275]	[158,202,73,83]	4	hSpCas9	negative selection	6638561
68025549	68025572	10	-	27260156	HS294T	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.5228646730183368	[435]	[184,244,268,280]	7	hSpCas9	negative selection	6638562
68072933	68072956	10	-	27260156	HS294T	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.7228879623810913	[163]	[39,42,32,36]	-8	hSpCas9	negative selection	6702821
68073097	68073120	10	-	27260156	HS294T	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.07938827115767388	[1434]	[612,739,495,465]	1	hSpCas9	negative selection	6702822
68025631	68025654	10	-	27260156	HS294T	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.3087914288685998	[195]	[46,71,62,63]	-4	hSpCas9	negative selection	6702823
68014025	68014048	10	-	27260156	HCC44	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	-0.017251355701333293	[629]	[748,676,804,607]	0	hSpCas9	negative selection	6759811
68014142	68014165	10	+	27260156	HCC44	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.550760509172998	[275]	[361,70,324,147]	-7	hSpCas9	negative selection	6759812
68025549	68025572	10	-	27260156	HCC44	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.13277733846619375	[435]	[580,494,605,498]	2	hSpCas9	negative selection	6759813
68072933	68072956	10	-	27260156	HCC44	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.614178494755711	[163]	[157,110,159,67]	-7	hSpCas9	negative selection	6824072
68073097	68073120	10	-	27260156	HCC44	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.13032176221471592	[1434]	[1568,1226,1799,1423]	-2	hSpCas9	negative selection	6824073
68025631	68025654	10	-	27260156	HCC44	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.08842132875909936	[195]	[231,201,118,264]	-1	hSpCas9	negative selection	6824074
68014025	68014048	10	-	27260156	G402	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.015351806371885879	[629]	[1009,761,618,747]	0	hSpCas9	negative selection	6881062
68014142	68014165	10	+	27260156	G402	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.04654236706638759	[275]	[478,295,370,263]	0	hSpCas9	negative selection	6881063
68025549	68025572	10	-	27260156	G402	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.49747576493054363	[435]	[581,905,642,849]	6	hSpCas9	negative selection	6881064
68072933	68072956	10	-	27260156	G402	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.33549418802063324	[163]	[240,222,81,105]	-4	hSpCas9	negative selection	6945323
68073097	68073120	10	-	27260156	G402	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.1193584674487782	[1434]	[1863,1211,1327,2029]	-1	hSpCas9	negative selection	6945324
68025631	68025654	10	-	27260156	G402	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.1412109573296565	[195]	[209,130,528,172]	1	hSpCas9	negative selection	6945325
68014025	68014048	10	-	27260156	L33	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.09008613598179949	[629]	[716,269,423,630]	2	hSpCas9	negative selection	7002313
68014142	68014165	10	+	27260156	L33	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.08527710955689372	[275]	[250,169,166,240]	2	hSpCas9	negative selection	7002314
68025549	68025572	10	-	27260156	L33	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.29488381275330633	[435]	[522,227,303,575]	6	hSpCas9	negative selection	7002315
68072933	68072956	10	-	27260156	L33	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.9486204924006172	[163]	[64,62,41,54]	-9	hSpCas9	negative selection	7066574
68073097	68073120	10	-	27260156	L33	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.2589144201758211	[1434]	[1024,471,775,1387]	-5	hSpCas9	negative selection	7066575
68025631	68025654	10	-	27260156	L33	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.034300814358755094	[195]	[190,86,71,283]	0	hSpCas9	negative selection	7066576
68014025	68014048	10	-	27260156	K562	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.36877837655399304	[629]	[1048,357,977,529]	4	hSpCas9	negative selection	7123564
68014142	68014165	10	+	27260156	K562	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.2758679601161915	[275]	[301,414,266,216]	3	hSpCas9	negative selection	7123565
68025549	68025572	10	-	27260156	K562	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.5771792743881463	[435]	[360,887,665,409]	7	hSpCas9	negative selection	7123566
68072933	68072956	10	-	27260156	K562	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.8799633063361405	[163]	[85,34,92,97]	-7	hSpCas9	negative selection	7187825
68073097	68073120	10	-	27260156	K562	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.36234543400881614	[1434]	[1041,1244,765,929]	-4	hSpCas9	negative selection	7187826
68025631	68025654	10	-	27260156	K562	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.20397756700089942	[195]	[154,100,183,159]	-3	hSpCas9	negative selection	7187827
68014025	68014048	10	-	27260156	HT29	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.37927802176975334	[629]	[1065,1106,947,884]	7	hSpCas9	negative selection	7244815
68014142	68014165	10	+	27260156	HT29	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.25161065814864136	[275]	[384,315,516,371]	5	hSpCas9	negative selection	7244816
68025549	68025572	10	-	27260156	HT29	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.265677357775815	[435]	[772,565,541,663]	5	hSpCas9	negative selection	7244817
68072933	68072956	10	-	27260156	HT29	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.0948160974704344	[163]	[306,325,92,148]	1	hSpCas9	negative selection	7309076
68073097	68073120	10	-	27260156	HT29	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.21474228165517206	[1434]	[1757,1608,1354,1329]	-4	hSpCas9	negative selection	7309077
68025631	68025654	10	-	27260156	HT29	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.19260247828864396	[195]	[324,290,250,230]	4	hSpCas9	negative selection	7309078
68014025	68014048	10	-	27260156	MHHES1	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.36042474364106536	[629]	[1123,937,1038,619]	6	hSpCas9	negative selection	7366066
68014142	68014165	10	+	27260156	MHHES1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.27912974580000044	[275]	[508,281,443,291]	5	hSpCas9	negative selection	7366067
68025549	68025572	10	-	27260156	MHHES1	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.5018086795049076	[435]	[854,870,504,593]	8	hSpCas9	negative selection	7366068
68072933	68072956	10	-	27260156	MHHES1	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.11172796832094933	[163]	[206,159,255,173]	2	hSpCas9	negative selection	7430327
68073097	68073120	10	-	27260156	MHHES1	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.2294413114804159	[1434]	[1706,1488,1546,903]	-4	hSpCas9	negative selection	7430328
68025631	68025654	10	-	27260156	MHHES1	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.15032335540525765	[195]	[272,165,171,187]	-3	hSpCas9	negative selection	7430329
68014025	68014048	10	-	27260156	MEWO	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.15163753589768636	[629]	[728,536,712]	3	hSpCas9	negative selection	7487317
68014142	68014165	10	+	27260156	MEWO	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.12436083456105951	[275]	[212,292,324]	2	hSpCas9	negative selection	7487318
68025549	68025572	10	-	27260156	MEWO	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.30804973317362083	[435]	[447,472,582]	6	hSpCas9	negative selection	7487319
68072933	68072956	10	-	27260156	MEWO	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.42256718990775743	[163]	[122,124,96]	-7	hSpCas9	negative selection	7551578
68073097	68073120	10	-	27260156	MEWO	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.1908999957808275	[1434]	[1517,1048,1027]	-4	hSpCas9	negative selection	7551579
68025631	68025654	10	-	27260156	MEWO	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.34567999005482053	[195]	[283,207,216]	7	hSpCas9	negative selection	7551580
68014025	68014048	10	-	27260156	LNCAPCLONEFGC	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.3838046323874682	[629]	[681,746,804,753]	6	hSpCas9	negative selection	7608568
68014142	68014165	10	+	27260156	LNCAPCLONEFGC	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.13552970007419896	[275]	[244,348,206,282]	2	hSpCas9	negative selection	7608569
68025549	68025572	10	-	27260156	LNCAPCLONEFGC	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.30963281766040374	[435]	[398,451,543,574]	5	hSpCas9	negative selection	7608570
68072933	68072956	10	-	27260156	LNCAPCLONEFGC	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.29551032361815266	[163]	[91,135,129,126]	-4	hSpCas9	negative selection	7672829
68073097	68073120	10	-	27260156	LNCAPCLONEFGC	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.05777613382814151	[1434]	[1465,1095,1460,1008]	-1	hSpCas9	negative selection	7672830
68025631	68025654	10	-	27260156	LNCAPCLONEFGC	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.16601027086408782	[195]	[187,140,134,165]	-3	hSpCas9	negative selection	7672831
68014025	68014048	10	-	27260156	PANC0327	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.2264172497532444	[629]	[570,578,854,616]	3	hSpCas9	negative selection	7729819
68014142	68014165	10	+	27260156	PANC0327	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.49426167107177676	[275]	[151,208,233,94]	-6	hSpCas9	negative selection	7729820
68025549	68025572	10	-	27260156	PANC0327	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.5394030806883637	[435]	[458,481,475,835]	7	hSpCas9	negative selection	7729821
68072933	68072956	10	-	27260156	PANC0327	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.34999699811518137	[163]	[198,298,90,139]	5	hSpCas9	negative selection	7794080
68073097	68073120	10	-	27260156	PANC0327	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.32083663842356236	[1434]	[1290,1213,849,723]	-5	hSpCas9	negative selection	7794081
68025631	68025654	10	-	27260156	PANC0327	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.11041391955453084	[195]	[156,258,147,175]	1	hSpCas9	negative selection	7794082
68014025	68014048	10	-	27260156	NCIH2009	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.660569650296319	[629]	[1526,1308,1363]	8	hSpCas9	negative selection	7851070
68014142	68014165	10	+	27260156	NCIH2009	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.08475304118757421	[275]	[357,369,360]	-1	hSpCas9	negative selection	7851071
68025549	68025572	10	-	27260156	NCIH2009	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.5890276387388569	[435]	[1007,889,867]	7	hSpCas9	negative selection	7851072
68072933	68072956	10	-	27260156	NCIH2009	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.18679318022020275	[163]	[330,157,140]	-3	hSpCas9	negative selection	7915331
68073097	68073120	10	-	27260156	NCIH2009	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.07154347914381343	[1434]	[2219,1698,1866]	-1	hSpCas9	negative selection	7915332
68025631	68025654	10	-	27260156	NCIH2009	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.000325446582262634	[195]	[300,287,236]	0	hSpCas9	negative selection	7915333
68014025	68014048	10	-	27260156	NCIH1373	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	-0.32374867653101386	[629]	[374,559,470,219]	-3	hSpCas9	negative selection	7972321
68014142	68014165	10	+	27260156	NCIH1373	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.17595563887992416	[275]	[302,232,253,82]	-2	hSpCas9	negative selection	7972322
68025549	68025572	10	-	27260156	NCIH1373	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	-0.4419839335941719	[435]	[499,307,362,75]	-4	hSpCas9	negative selection	7972323
68072933	68072956	10	-	27260156	NCIH1373	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.5154580552226644	[163]	[40,141,79,63]	-5	hSpCas9	negative selection	8036582
68073097	68073120	10	-	27260156	NCIH1373	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.2937057817391009	[1434]	[1809,2296,1933,462]	3	hSpCas9	negative selection	8036583
68025631	68025654	10	-	27260156	NCIH1373	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.9398635637900634	[195]	[31,194,101,27]	-7	hSpCas9	negative selection	8036584
68014025	68014048	10	-	27260156	PATU8902	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.18243634241270068	[629]	[900,808,1156,1075]	1	hSpCas9	negative selection	8093572
68014142	68014165	10	+	27260156	PATU8902	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.9757860761132088	[275]	[188,353,97,160]	-7	hSpCas9	negative selection	8093573
68025549	68025572	10	-	27260156	PATU8902	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	-0.15807884691560065	[435]	[486,789,434,482]	-2	hSpCas9	negative selection	8093574
68072933	68072956	10	-	27260156	PATU8902	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.4489728464279257	[163]	[113,87,167,315]	-4	hSpCas9	negative selection	8157833
68073097	68073120	10	-	27260156	PATU8902	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.02771610832895699	[1434]	[1554,1820,1679,3329]	0	hSpCas9	negative selection	8157834
68025631	68025654	10	-	27260156	PATU8902	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.733051251868359	[195]	[175,241,55,215]	-6	hSpCas9	negative selection	8157835
68014025	68014048	10	-	27260156	PANC1	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.01740288935790324	[629]	[485,498,636,550]	0	hSpCas9	negative selection	8214823
68014142	68014165	10	+	27260156	PANC1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.1626341595749533	[275]	[210,270,198,179]	-3	hSpCas9	negative selection	8214824
68025549	68025572	10	-	27260156	PANC1	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.2023778204631066	[435]	[271,528,471,461]	3	hSpCas9	negative selection	8214825
68072933	68072956	10	-	27260156	PANC1	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.48815151437957205	[163]	[102,88,100,103]	-6	hSpCas9	negative selection	8279084
68073097	68073120	10	-	27260156	PANC1	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.022124490285473586	[1434]	[1144,1614,1038,1259]	0	hSpCas9	negative selection	8279085
68025631	68025654	10	-	27260156	PANC1	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.05310162858559786	[195]	[103,194,96,243]	-1	hSpCas9	negative selection	8279086
68014025	68014048	10	-	27260156	PANC0813	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.19135998837890833	[629]	[757,984,865,765]	3	hSpCas9	negative selection	8336074
68014142	68014165	10	+	27260156	PANC0813	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.054531474534871616	[275]	[288,284,340,421]	0	hSpCas9	negative selection	8336075
68025549	68025572	10	-	27260156	PANC0813	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.1331909814035451	[435]	[639,542,494,573]	2	hSpCas9	negative selection	8336076
68072933	68072956	10	-	27260156	PANC0813	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.3037493988226667	[163]	[159,124,122,212]	-5	hSpCas9	negative selection	8400335
68073097	68073120	10	-	27260156	PANC0813	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.14097315234266317	[1434]	[1967,1684,1689,2084]	2	hSpCas9	negative selection	8400336
68025631	68025654	10	-	27260156	PANC0813	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.08868099351744507	[195]	[265,178,204,219]	-1	hSpCas9	negative selection	8400337
68014025	68014048	10	-	27260156	RDES	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.23480547186453482	[629]	[753,717,1016,949]	4	hSpCas9	negative selection	8457325
68014142	68014165	10	+	27260156	RDES	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.1937251836774817	[275]	[180,401,273,248]	-3	hSpCas9	negative selection	8457326
68025549	68025572	10	-	27260156	RDES	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.18011048627924253	[435]	[429,491,727,663]	3	hSpCas9	negative selection	8457327
68072933	68072956	10	-	27260156	RDES	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.7725367578965452	[163]	[72,112,143,118]	-8	hSpCas9	negative selection	8521586
68073097	68073120	10	-	27260156	RDES	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	0.053654999707440254	[1434]	[1451,1499,1878,2111]	0	hSpCas9	negative selection	8521587
68025631	68025654	10	-	27260156	RDES	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.07223605475994388	[195]	[193,190,243,341]	1	hSpCas9	negative selection	8521588
68014025	68014048	10	-	27260156	PC3	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.19865120222794297	[629]	[394,683,1196,881]	4	hSpCas9	negative selection	8578576
68014142	68014165	10	+	27260156	PC3	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.385525698374689	[275]	[141,178,415,194]	-7	hSpCas9	negative selection	8578577
68025549	68025572	10	-	27260156	PC3	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.20488135643859107	[435]	[274,448,994,537]	4	hSpCas9	negative selection	8578578
68072933	68072956	10	-	27260156	PC3	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-1.0320864461755224	[163]	[51,80,117,87]	-9	hSpCas9	negative selection	8642837
68073097	68073120	10	-	27260156	PC3	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.2758154588593005	[1434]	[595,1122,2562,1146]	-6	hSpCas9	negative selection	8642838
68025631	68025654	10	-	27260156	PC3	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.18034854414650914	[195]	[85,196,249,210]	-4	hSpCas9	negative selection	8642839
68014025	68014048	10	-	27260156	PATU8988T	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.47612037792864337	[629]	[890,754,893,836]	7	hSpCas9	negative selection	8699827
68014142	68014165	10	+	27260156	PATU8988T	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.21026963151347	[275]	[168,189,355,198]	-4	hSpCas9	negative selection	8699828
68025549	68025572	10	-	27260156	PATU8988T	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.1478201992692617	[435]	[487,394,398,588]	2	hSpCas9	negative selection	8699829
68072933	68072956	10	-	27260156	PATU8988T	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.6921070344297733	[163]	[126,94,85,82]	-8	hSpCas9	negative selection	8764088
68073097	68073120	10	-	27260156	PATU8988T	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.2640605344437501	[1434]	[1027,1601,1087,924]	-4	hSpCas9	negative selection	8764089
68025631	68025654	10	-	27260156	PATU8988T	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.5698192015993313	[195]	[123,170,110,106]	-7	hSpCas9	negative selection	8764090
68014025	68014048	10	-	27260156	T47D	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.2357981284406716	[629]	[847,857,903,845]	5	hSpCas9	negative selection	8821078
68014142	68014165	10	+	27260156	T47D	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.02360394728387183	[275]	[326,334,290,354]	0	hSpCas9	negative selection	8821079
68025549	68025572	10	-	27260156	T47D	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.23259453205660918	[435]	[538,573,645,629]	5	hSpCas9	negative selection	8821080
68072933	68072956	10	-	27260156	T47D	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.3991745964520088	[163]	[114,86,173,209]	-7	hSpCas9	negative selection	8885339
68073097	68073120	10	-	27260156	T47D	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.1239326663047533	[1434]	[1684,1440,1313,1713]	-3	hSpCas9	negative selection	8885340
68025631	68025654	10	-	27260156	T47D	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.07930717420854516	[195]	[237,237,268,218]	1	hSpCas9	negative selection	8885341
68014025	68014048	10	-	27260156	SU8686	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.1266781732793788	[629]	[676,611,654,807]	2	hSpCas9	negative selection	8942329
68014142	68014165	10	+	27260156	SU8686	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.13309751469227016	[275]	[262,216,247,274]	-2	hSpCas9	negative selection	8942330
68025549	68025572	10	-	27260156	SU8686	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.45292572632548095	[435]	[562,524,611,690]	7	hSpCas9	negative selection	8942331
68072933	68072956	10	-	27260156	SU8686	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-1.176083481365204	[163]	[24,67,140,58]	-9	hSpCas9	negative selection	9006590
68073097	68073120	10	-	27260156	SU8686	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.07125447634119508	[1434]	[1325,1035,1422,1728]	-1	hSpCas9	negative selection	9006591
68025631	68025654	10	-	27260156	SU8686	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	-0.03553160508466058	[195]	[175,199,254,115]	0	hSpCas9	negative selection	9006592
68014025	68014048	10	-	27260156	SKES1	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.11720387017792655	[629]	[726,754,708,557]	2	hSpCas9	negative selection	9063580
68014142	68014165	10	+	27260156	SKES1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.008270831005998236	[275]	[445,318,190,188]	0	hSpCas9	negative selection	9063581
68025549	68025572	10	-	27260156	SKES1	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.1547323437251108	[435]	[389,570,484,482]	3	hSpCas9	negative selection	9063582
68072933	68072956	10	-	27260156	SKES1	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.4682088113721625	[163]	[102,123,163,82]	-8	hSpCas9	negative selection	9127841
68073097	68073120	10	-	27260156	SKES1	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.39090990358362343	[1434]	[1366,1223,906,932]	-7	hSpCas9	negative selection	9127842
68025631	68025654	10	-	27260156	SKES1	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.3052310852018276	[195]	[219,327,265,165]	6	hSpCas9	negative selection	9127843
68014025	68014048	10	-	27260156	TOV112D	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.19439464836921938	[629]	[747,708,642,783]	4	hSpCas9	negative selection	9184831
68014142	68014165	10	+	27260156	TOV112D	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.03987092171008544	[275]	[372,195,265,231]	-1	hSpCas9	negative selection	9184832
68025549	68025572	10	-	27260156	TOV112D	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.31388501714636013	[435]	[682,593,492,427]	6	hSpCas9	negative selection	9184833
68072933	68072956	10	-	27260156	TOV112D	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.5710737294906889	[163]	[189,96,68,89]	-8	hSpCas9	negative selection	9249092
68073097	68073120	10	-	27260156	TOV112D	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.255254885840803	[1434]	[1038,1206,1298,1254]	-5	hSpCas9	negative selection	9249093
68025631	68025654	10	-	27260156	TOV112D	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.2460588002430577	[195]	[185,375,161,237]	5	hSpCas9	negative selection	9249094
68014025	68014048	10	-	27260156	TC71	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.20170471979759363	[629]	[735,716,737,926]	5	hSpCas9	negative selection	9306082
68014142	68014165	10	+	27260156	TC71	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.12519304014170018	[275]	[320,359,226,389]	3	hSpCas9	negative selection	9306083
68025549	68025572	10	-	27260156	TC71	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.28331150708394515	[435]	[642,550,504,576]	7	hSpCas9	negative selection	9306084
68072933	68072956	10	-	27260156	TC71	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	0.011825273787819723	[163]	[233,175,166,127]	0	hSpCas9	negative selection	9370343
68073097	68073120	10	-	27260156	TC71	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.22227834886028286	[1434]	[1131,1459,1324,1363]	-5	hSpCas9	negative selection	9370344
68025631	68025654	10	-	27260156	TC71	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.3026882699335419	[195]	[257,210,316,247]	7	hSpCas9	negative selection	9370345
68014025	68014048	10	-	27260156	TC32	viability	GGGCAGTGTCTACCAGATATTGG	HERC4	ENSG00000148634	0.18624771060053302	[629]	[647,583,796,681]	3	hSpCas9	negative selection	9427333
68014142	68014165	10	+	27260156	TC32	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.16311003176719086	[275]	[204,384,252,264]	3	hSpCas9	negative selection	9427334
68025549	68025572	10	-	27260156	TC32	viability	ATTGTCACTGAGATTGCTTGTGG	HERC4	ENSG00000148634	0.10112181095075566	[435]	[490,283,553,476]	1	hSpCas9	negative selection	9427335
68072933	68072956	10	-	27260156	TC32	viability	GATGGAACAGTGTACACATGTGG	HERC4	ENSG00000148634	-0.33992448527034	[163]	[116,117,127,118]	-6	hSpCas9	negative selection	9491594
68073097	68073120	10	-	27260156	TC32	viability	TAATTACAAGCATGTTGTGCTGG	HERC4	ENSG00000148634	-0.14638690767466378	[1434]	[1086,1053,1653,1153]	-3	hSpCas9	negative selection	9491595
68025631	68025654	10	-	27260156	TC32	viability	AGCTGGAGGGTATGGTCAGTTGG	HERC4	ENSG00000148634	0.5788035454973729	[195]	[119,310,308,359]	8	hSpCas9	negative selection	9491596
67966694	67966717	10	-	27869803	HPAFII	viability after 27 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.3560866586820869	[188]	[136,118,NaN]	3	hSpCas9	negative selection	9538321
67990903	67990926	10	-	27869803	HPAFII	viability after 27 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.4048865772411646	[235]	[148,176,NaN]	3	hSpCas9	negative selection	9538322
67991154	67991177	10	+	27869803	HPAFII	viability after 27 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.3294766365021033	[253]	[138,78,NaN]	-2	hSpCas9	negative selection	9538323
67992208	67992231	10	+	27869803	HPAFII	viability after 27 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.6776022013673559	[179]	[212,99,NaN]	5	hSpCas9	negative selection	9538324
68034058	68034081	10	+	27869803	HPAFII	viability after 27 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.3264395616559115	[802]	[350,677,NaN]	2	hSpCas9	negative selection	9538325
68044477	68044500	10	-	27869803	HPAFII	viability after 27 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.5026372121236969	[92]	[59,76,NaN]	4	hSpCas9	negative selection	9538326
67966694	67966717	10	-	27869803	HPAFII	viability after 15 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.30336557833865435	[188]	[344,191,NaN]	3	hSpCas9	negative selection	9620770
67990903	67990926	10	-	27869803	HPAFII	viability after 15 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.3120808089482774	[235]	[370,279,NaN]	3	hSpCas9	negative selection	9620771
67991154	67991177	10	+	27869803	HPAFII	viability after 15 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.11820384162965963	[253]	[499,96,NaN]	-1	hSpCas9	negative selection	9620772
67992208	67992231	10	+	27869803	HPAFII	viability after 15 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.0239583816864839	[179]	[274,147,NaN]	0	hSpCas9	negative selection	9620773
68034058	68034081	10	+	27869803	HPAFII	viability after 15 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.08846723037405169	[802]	[932,907,NaN]	1	hSpCas9	negative selection	9620774
68044477	68044500	10	-	27869803	HPAFII	viability after 15 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.7332109220561094	[92]	[167,164,NaN]	7	hSpCas9	negative selection	9620775
67966694	67966717	10	-	27869803	ASPC1	viability after 36 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.7958409405047002	[634]	[625,377,216]	7	hSpCas9	negative selection	9703219
67990903	67990926	10	-	27869803	ASPC1	viability after 36 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.43185634497185044	[552]	[379,181,235]	4	hSpCas9	negative selection	9703220
67991154	67991177	10	+	27869803	ASPC1	viability after 36 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-1.0793535844987368	[632]	[144,110,69]	-8	hSpCas9	negative selection	9703221
67992208	67992231	10	+	27869803	ASPC1	viability after 36 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.8024866181473603	[394]	[12,206,22]	-7	hSpCas9	negative selection	9703222
68034058	68034081	10	+	27869803	ASPC1	viability after 36 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.33354460308346523	[2009]	[1414,895,492]	3	hSpCas9	negative selection	9703223
68044477	68044500	10	-	27869803	ASPC1	viability after 36 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-1.0138389672292862	[391]	[45,110,47]	-7	hSpCas9	negative selection	9703224
67966694	67966717	10	-	27869803	PATU8988S	viability after 35 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	-0.09184846625670362	[549]	[141,273,NaN]	-1	hSpCas9	negative selection	9785668
67990903	67990926	10	-	27869803	PATU8988S	viability after 35 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.00449028522440742	[379]	[182,121,NaN]	0	hSpCas9	negative selection	9785669
67991154	67991177	10	+	27869803	PATU8988S	viability after 35 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	1.1053675043297853	[426]	[373,365,NaN]	9	hSpCas9	negative selection	9785670
67992208	67992231	10	+	27869803	PATU8988S	viability after 35 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.5299470072982989	[352]	[82,113,NaN]	-5	hSpCas9	negative selection	9785671
68034058	68034081	10	+	27869803	PATU8988S	viability after 35 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	-0.027499540449396287	[1374]	[685,399,NaN]	0	hSpCas9	negative selection	9785672
68044477	68044500	10	-	27869803	PATU8988S	viability after 35 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.698907050067173	[237]	[80,36,NaN]	-6	hSpCas9	negative selection	9785673
67966694	67966717	10	-	27869803	PATU8988S	viability after 31 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.08476570931234158	[549]	[137,352,NaN]	1	hSpCas9	negative selection	9868117
67990903	67990926	10	-	27869803	PATU8988S	viability after 31 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	-0.2967042314134005	[379]	[103,147,NaN]	-3	hSpCas9	negative selection	9868118
67991154	67991177	10	+	27869803	PATU8988S	viability after 31 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	1.205836149973342	[426]	[335,464,NaN]	9	hSpCas9	negative selection	9868119
67992208	67992231	10	+	27869803	PATU8988S	viability after 31 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	-0.8487639155144039	[352]	[60,99,NaN]	-7	hSpCas9	negative selection	9868120
68034058	68034081	10	+	27869803	PATU8988S	viability after 31 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.3782431144458993	[1374]	[815,580,NaN]	4	hSpCas9	negative selection	9868121
68044477	68044500	10	-	27869803	PATU8988S	viability after 31 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	-0.8756065912159607	[237]	[67,30,NaN]	-7	hSpCas9	negative selection	9868122
67966694	67966717	10	-	27869803	HPAFII	viability after 35 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.3407814598223987	[188]	[115,126,NaN]	2	hSpCas9	negative selection	9950566
67990903	67990926	10	-	27869803	HPAFII	viability after 35 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.510680139756224	[235]	[133,210,NaN]	3	hSpCas9	negative selection	9950567
67991154	67991177	10	+	27869803	HPAFII	viability after 35 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.12530681980603667	[253]	[131,101,NaN]	-1	hSpCas9	negative selection	9950568
67992208	67992231	10	+	27869803	HPAFII	viability after 35 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.8605265731157619	[179]	[251,67,NaN]	5	hSpCas9	negative selection	9950569
68034058	68034081	10	+	27869803	HPAFII	viability after 35 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.394232920143504	[802]	[347,743,NaN]	2	hSpCas9	negative selection	9950570
68044477	68044500	10	-	27869803	HPAFII	viability after 35 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.4024506725335735	[92]	[49,75,NaN]	2	hSpCas9	negative selection	9950571
67966694	67966717	10	-	27869803	HPAFII	viability after 31 days	TATCAACTGGGTCCAACAGCAGG	HERC4	ENSG00000148634	0.4054817488670479	[188]	[117,164,NaN]	3	hSpCas9	negative selection	10033015
67990903	67990926	10	-	27869803	HPAFII	viability after 31 days	TCATCCGCAGATATCTCAGCAGG	HERC4	ENSG00000148634	0.3811209618169945	[235]	[149,196,NaN]	2	hSpCas9	negative selection	10033016
67991154	67991177	10	+	27869803	HPAFII	viability after 31 days	ACTTCCATTTAGGCAACCAGAGG	HERC4	ENSG00000148634	-0.5009843387858364	[253]	[116,82,NaN]	-3	hSpCas9	negative selection	10033017
67992208	67992231	10	+	27869803	HPAFII	viability after 31 days	TCCACAGGAAACCTTCCAGAAGG	HERC4	ENSG00000148634	0.6640257360732278	[179]	[194,121,NaN]	5	hSpCas9	negative selection	10033018
68034058	68034081	10	+	27869803	HPAFII	viability after 31 days	CTGCTGCAACTTGCATGAAAGGG	HERC4	ENSG00000148634	0.5549892138141657	[802]	[462,878,NaN]	4	hSpCas9	negative selection	10033019
68044477	68044500	10	-	27869803	HPAFII	viability after 31 days	AGCGCTAAATGACAAAGGCCAGG	HERC4	ENSG00000148634	0.6183286282015851	[92]	[93,64,NaN]	4	hSpCas9	negative selection	10033020
67954701	67954724	10	-	28162770	P31FUJ	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.5640081128897518	[194]	[154]	-5	hSpCas9	negative selection	10168392
67990239	67990262	10	+	28162770	P31FUJ	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.5442115503918953	[404]	[693]	6	hSpCas9	negative selection	10168393
68025596	68025619	10	-	28162770	P31FUJ	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.8062690662977052	[249]	[167]	-6	hSpCas9	negative selection	10168394
67992292	67992315	10	+	28162770	P31FUJ	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.15607641377155013	[237]	[250]	-1	hSpCas9	negative selection	10168395
67955043	67955066	10	-	28162770	P31FUJ	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	1.0514062245238252	[61]	[150]	9	hSpCas9	negative selection	10168396
67932638	67932661	10	-	28162770	P31FUJ	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.8588282710511895	[121]	[259]	8	hSpCas9	negative selection	10168397
68044423	68044446	10	-	28162770	P31FUJ	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.5667630161092299	[450]	[784]	6	hSpCas9	negative selection	10168398
68014142	68014165	10	+	28162770	P31FUJ	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.2437879717322211	[888]	[1236]	2	hSpCas9	negative selection	10168399
68014090	68014113	10	-	28162770	P31FUJ	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.7021702287296693	[328]	[628]	7	hSpCas9	negative selection	10168400
68014035	68014058	10	+	28162770	P31FUJ	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	-0.24752371012114424	[196]	[194]	-2	hSpCas9	negative selection	10168401
67954701	67954724	10	-	28162770	TF1	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10337758
67990239	67990262	10	+	28162770	TF1	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	NaN	[NaN]	[287]	1	hSpCas9	negative selection	10337759
68025596	68025619	10	-	28162770	TF1	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10337760
67992292	67992315	10	+	28162770	TF1	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10337761
67955043	67955066	10	-	28162770	TF1	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10337762
67932638	67932661	10	-	28162770	TF1	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10337763
68044423	68044446	10	-	28162770	TF1	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	NaN	[NaN]	[486]	1	hSpCas9	negative selection	10337764
68014142	68014165	10	+	28162770	TF1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	NaN	[NaN]	[738]	1	hSpCas9	negative selection	10337765
68014090	68014113	10	-	28162770	TF1	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	NaN	[NaN]	[210]	1	hSpCas9	negative selection	10337766
68014035	68014058	10	+	28162770	TF1	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10337767
67954701	67954724	10	-	28162770	SKM1	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.5813539962092029	[61]	[163]	5	hSpCas9	negative selection	10507124
67990239	67990262	10	+	28162770	SKM1	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	-0.14188196426050914	[87]	[140]	-1	hSpCas9	negative selection	10507125
68025596	68025619	10	-	28162770	SKM1	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.17511144815764756	[75]	[118]	-1	hSpCas9	negative selection	10507126
67992292	67992315	10	+	28162770	SKM1	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-1.0260155900435988	[90]	[78]	-6	hSpCas9	negative selection	10507127
67955043	67955066	10	-	28162770	SKM1	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-0.7109703856332619	[24]	[26]	-5	hSpCas9	negative selection	10507128
67932638	67932661	10	-	28162770	SKM1	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.42761219204946677	[44]	[106]	4	hSpCas9	negative selection	10507129
68044423	68044446	10	-	28162770	SKM1	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	1.4390711914785024	[91]	[440]	9	hSpCas9	negative selection	10507130
68014142	68014165	10	+	28162770	SKM1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.011196726394635093	[178]	[313]	0	hSpCas9	negative selection	10507131
68014090	68014113	10	-	28162770	SKM1	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-0.28497367436455123	[50]	[73]	-2	hSpCas9	negative selection	10507132
68014035	68014058	10	+	28162770	SKM1	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.6202206305830686	[45]	[124]	6	hSpCas9	negative selection	10507133
67954701	67954724	10	-	28162770	SKM1	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.5813539962092029	[61]	[163]	5	hSpCas9	negative selection	10676490
67990239	67990262	10	+	28162770	SKM1	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	-0.14188196426050914	[87]	[140]	-1	hSpCas9	negative selection	10676491
68025596	68025619	10	-	28162770	SKM1	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.17511144815764756	[75]	[118]	-1	hSpCas9	negative selection	10676492
67992292	67992315	10	+	28162770	SKM1	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-1.0260155900435988	[90]	[78]	-6	hSpCas9	negative selection	10676493
67955043	67955066	10	-	28162770	SKM1	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-0.7109703856332619	[24]	[26]	-5	hSpCas9	negative selection	10676494
67932638	67932661	10	-	28162770	SKM1	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.42761219204946677	[44]	[106]	4	hSpCas9	negative selection	10676495
68044423	68044446	10	-	28162770	SKM1	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	1.4390711914785024	[91]	[440]	9	hSpCas9	negative selection	10676496
68014142	68014165	10	+	28162770	SKM1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	-0.011196726394635093	[178]	[313]	0	hSpCas9	negative selection	10676497
68014090	68014113	10	-	28162770	SKM1	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-0.28497367436455123	[50]	[73]	-2	hSpCas9	negative selection	10676498
68014035	68014058	10	+	28162770	SKM1	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.6202206305830686	[45]	[124]	6	hSpCas9	negative selection	10676499
67954701	67954724	10	-	28162770	PL21	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.059277078649470405	[257]	[116]	0	hSpCas9	negative selection	10845856
67990239	67990262	10	+	28162770	PL21	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	-1.3198674443910663	[303]	[52]	-7	hSpCas9	negative selection	10845857
68025596	68025619	10	-	28162770	PL21	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.32406885515274	[278]	[96]	-2	hSpCas9	negative selection	10845858
67992292	67992315	10	+	28162770	PL21	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.607215307568284	[286]	[81]	-4	hSpCas9	negative selection	10845859
67955043	67955066	10	-	28162770	PL21	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-0.6960245745261402	[66]	[17]	-5	hSpCas9	negative selection	10845860
67932638	67932661	10	-	28162770	PL21	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.2799929221785347	[122]	[64]	2	hSpCas9	negative selection	10845861
68044423	68044446	10	-	28162770	PL21	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.6151771137681639	[299]	[199]	5	hSpCas9	negative selection	10845862
68014142	68014165	10	+	28162770	PL21	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	1.1036484053568147	[540]	[505]	8	hSpCas9	negative selection	10845863
68014090	68014113	10	-	28162770	PL21	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.07895326796926241	[210]	[96]	0	hSpCas9	negative selection	10845864
68014035	68014058	10	+	28162770	PL21	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	1.038388544492708	[131]	[117]	8	hSpCas9	negative selection	10845865
67954701	67954724	10	-	28162770	P31FUJ	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.5640081128897518	[194]	[154]	-5	hSpCas9	negative selection	11015222
67990239	67990262	10	+	28162770	P31FUJ	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.5442115503918953	[404]	[693]	6	hSpCas9	negative selection	11015223
68025596	68025619	10	-	28162770	P31FUJ	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.8062690662977052	[249]	[167]	-6	hSpCas9	negative selection	11015224
67992292	67992315	10	+	28162770	P31FUJ	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.15607641377155013	[237]	[250]	-1	hSpCas9	negative selection	11015225
67955043	67955066	10	-	28162770	P31FUJ	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	1.0514062245238252	[61]	[150]	9	hSpCas9	negative selection	11015226
67932638	67932661	10	-	28162770	P31FUJ	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.8588282710511895	[121]	[259]	8	hSpCas9	negative selection	11015227
68044423	68044446	10	-	28162770	P31FUJ	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.5667630161092299	[450]	[784]	6	hSpCas9	negative selection	11015228
68014142	68014165	10	+	28162770	P31FUJ	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.2437879717322211	[888]	[1236]	2	hSpCas9	negative selection	11015229
68014090	68014113	10	-	28162770	P31FUJ	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.7021702287296693	[328]	[628]	7	hSpCas9	negative selection	11015230
68014035	68014058	10	+	28162770	P31FUJ	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	-0.24752371012114424	[196]	[194]	-2	hSpCas9	negative selection	11015231
67954701	67954724	10	-	28162770	OCIAML5	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.9451759752554785	[159]	[149]	-5	hSpCas9	negative selection	11184588
67990239	67990262	10	+	28162770	OCIAML5	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	1.2922048857398094	[144]	[640]	9	hSpCas9	negative selection	11184589
68025596	68025619	10	-	28162770	OCIAML5	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.4242646575832545	[134]	[326]	3	hSpCas9	negative selection	11184590
67992292	67992315	10	+	28162770	OCIAML5	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.41948087037430615	[142]	[192]	-3	hSpCas9	negative selection	11184591
67955043	67955066	10	-	28162770	OCIAML5	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-0.7020411268593896	[72]	[80]	-4	hSpCas9	negative selection	11184592
67932638	67932661	10	-	28162770	OCIAML5	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.7515116080245062	[76]	[233]	6	hSpCas9	negative selection	11184593
68044423	68044446	10	-	28162770	OCIAML5	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.3588793238213428	[234]	[543]	3	hSpCas9	negative selection	11184594
68014142	68014165	10	+	28162770	OCIAML5	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.5098002693935093	[455]	[1171]	4	hSpCas9	negative selection	11184595
68014090	68014113	10	-	28162770	OCIAML5	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.5710232007095799	[200]	[538]	5	hSpCas9	negative selection	11184596
68014035	68014058	10	+	28162770	OCIAML5	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.29645595384609114	[82]	[183]	2	hSpCas9	negative selection	11184597
67954701	67954724	10	-	28162770	EOL1	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.711890946641707	[484]	[155]	-5	hSpCas9	negative selection	11353954
67990239	67990262	10	+	28162770	EOL1	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	2.1552114550477017	[322]	[757]	9	hSpCas9	negative selection	11353955
68025596	68025619	10	-	28162770	EOL1	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.18557285251004207	[478]	[286]	1	hSpCas9	negative selection	11353956
67992292	67992315	10	+	28162770	EOL1	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	0.8489607454231851	[430]	[408]	7	hSpCas9	negative selection	11353957
67955043	67955066	10	-	28162770	EOL1	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-1.405373114070358	[180]	[35]	-7	hSpCas9	negative selection	11353958
67932638	67932661	10	-	28162770	EOL1	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.26271650746510794	[211]	[133]	2	hSpCas9	negative selection	11353959
68044423	68044446	10	-	28162770	EOL1	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-0.0009052750644115148	[527]	[277]	0	hSpCas9	negative selection	11353960
68014142	68014165	10	+	28162770	EOL1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.36033085241298957	[793]	[536]	3	hSpCas9	negative selection	11353961
68014090	68014113	10	-	28162770	EOL1	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	1.0025502835718076	[233]	[246]	8	hSpCas9	negative selection	11353962
68014035	68014058	10	+	28162770	EOL1	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.2909753266247568	[165]	[106]	2	hSpCas9	negative selection	11353963
67954701	67954724	10	-	28162770	MOLM13	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.26137595394004526	[435]	[262]	-2	hSpCas9	negative selection	11523320
67990239	67990262	10	+	28162770	MOLM13	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.5302859186824463	[361]	[377]	4	hSpCas9	negative selection	11523321
68025596	68025619	10	-	28162770	MOLM13	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.17132535214559055	[295]	[240]	1	hSpCas9	negative selection	11523322
67992292	67992315	10	+	28162770	MOLM13	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	1.3726410663967628	[359]	[673]	9	hSpCas9	negative selection	11523323
67955043	67955066	10	-	28162770	MOLM13	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-1.7377856448469358	[142]	[30]	-7	hSpCas9	negative selection	11523324
67932638	67932661	10	-	28162770	MOLM13	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	-1.8269450524605084	[210]	[42]	-7	hSpCas9	negative selection	11523325
68044423	68044446	10	-	28162770	MOLM13	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-0.057130578720295255	[494]	[343]	0	hSpCas9	negative selection	11523326
68014142	68014165	10	+	28162770	MOLM13	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.47300835216959247	[843]	[846]	3	hSpCas9	negative selection	11523327
68014090	68014113	10	-	28162770	MOLM13	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-1.5032557557832358	[395]	[100]	-6	hSpCas9	negative selection	11523328
68014035	68014058	10	+	28162770	MOLM13	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	-0.34680751585419334	[196]	[111]	-2	hSpCas9	negative selection	11523329
67954701	67954724	10	-	28162770	HEL	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.6188129927548764	[303]	[298]	5	hSpCas9	negative selection	11692686
67990239	67990262	10	+	28162770	HEL	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	-0.290146972141106	[293]	[153]	-2	hSpCas9	negative selection	11692687
68025596	68025619	10	-	28162770	HEL	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.043701146067477936	[308]	[203]	0	hSpCas9	negative selection	11692688
67992292	67992315	10	+	28162770	HEL	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	-0.11214867016311142	[350]	[207]	-1	hSpCas9	negative selection	11692689
67955043	67955066	10	-	28162770	HEL	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	0.2531720202376313	[130]	[99]	2	hSpCas9	negative selection	11692690
67932638	67932661	10	-	28162770	HEL	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	1.2608681966567123	[128]	[197]	9	hSpCas9	negative selection	11692691
68044423	68044446	10	-	28162770	HEL	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.003736491566311839	[407]	[261]	0	hSpCas9	negative selection	11692692
68014142	68014165	10	+	28162770	HEL	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.024861708806465765	[797]	[519]	0	hSpCas9	negative selection	11692693
68014090	68014113	10	-	28162770	HEL	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-0.01457451294548312	[275]	[174]	0	hSpCas9	negative selection	11692694
68014035	68014058	10	+	28162770	HEL	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.31182195388573997	[160]	[127]	2	hSpCas9	negative selection	11692695
67954701	67954724	10	-	28162770	MV411	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.3629147682027112	[251]	[272]	3	hSpCas9	negative selection	11862052
67990239	67990262	10	+	28162770	MV411	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.33858543884097064	[229]	[244]	3	hSpCas9	negative selection	11862053
68025596	68025619	10	-	28162770	MV411	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.743863376902274	[223]	[315]	6	hSpCas9	negative selection	11862054
67992292	67992315	10	+	28162770	MV411	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	0.29270228451855723	[250]	[258]	2	hSpCas9	negative selection	11862055
67955043	67955066	10	-	28162770	MV411	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	0.657525834089886	[72]	[96]	6	hSpCas9	negative selection	11862056
67932638	67932661	10	-	28162770	MV411	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.2202160820477509	[106]	[104]	2	hSpCas9	negative selection	11862057
68044423	68044446	10	-	28162770	MV411	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	-0.9312683362017471	[411]	[181]	-6	hSpCas9	negative selection	11862058
68014142	68014165	10	+	28162770	MV411	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.2527907852769822	[537]	[539]	2	hSpCas9	negative selection	11862059
68014090	68014113	10	-	28162770	MV411	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.42964088200352435	[155]	[176]	4	hSpCas9	negative selection	11862060
68014035	68014058	10	+	28162770	MV411	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	-1.094253798926017	[146]	[57]	-6	hSpCas9	negative selection	11862061
67954701	67954724	10	-	28162770	MONOMAC1	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.13397435259024693	[189]	[238]	1	hSpCas9	negative selection	12031418
67990239	67990262	10	+	28162770	MONOMAC1	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	-0.7205988031165665	[183]	[127]	-5	hSpCas9	negative selection	12031419
68025596	68025619	10	-	28162770	MONOMAC1	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.3453168544618863	[214]	[193]	-3	hSpCas9	negative selection	12031420
67992292	67992315	10	+	28162770	MONOMAC1	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	0.9911668881010677	[182]	[416]	8	hSpCas9	negative selection	12031421
67955043	67955066	10	-	28162770	MONOMAC1	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	-0.9829120417067061	[49]	[28]	-7	hSpCas9	negative selection	12031422
67932638	67932661	10	-	28162770	MONOMAC1	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	-0.32441615353578135	[70]	[64]	-3	hSpCas9	negative selection	12031423
68044423	68044446	10	-	28162770	MONOMAC1	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.2939495054525887	[221]	[311]	3	hSpCas9	negative selection	12031424
68014142	68014165	10	+	28162770	MONOMAC1	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.47170007066670694	[406]	[646]	4	hSpCas9	negative selection	12031425
68014090	68014113	10	-	28162770	MONOMAC1	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	-0.21614567000725837	[75]	[74]	-2	hSpCas9	negative selection	12031426
68014035	68014058	10	+	28162770	MONOMAC1	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.15314950786932208	[90]	[115]	1	hSpCas9	negative selection	12031427
67954701	67954724	10	-	28162770	OCIAML2	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	0.13369800034592616	[36]	[224]	1	hSpCas9	negative selection	12200784
67990239	67990262	10	+	28162770	OCIAML2	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	0.7754445151259469	[40]	[388]	7	hSpCas9	negative selection	12200785
68025596	68025619	10	-	28162770	OCIAML2	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	-0.4501657226824457	[34]	[141]	-4	hSpCas9	negative selection	12200786
67992292	67992315	10	+	28162770	OCIAML2	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	0.5968331425365776	[46]	[393]	6	hSpCas9	negative selection	12200787
67955043	67955066	10	-	28162770	OCIAML2	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	0.3524924126737594	[12]	[91]	3	hSpCas9	negative selection	12200788
67932638	67932661	10	-	28162770	OCIAML2	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.592379972283639	[27]	[233]	6	hSpCas9	negative selection	12200789
68044423	68044446	10	-	28162770	OCIAML2	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	0.007961371678591012	[67]	[378]	0	hSpCas9	negative selection	12200790
68014142	68014165	10	+	28162770	OCIAML2	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.7696845040915492	[119]	[1133]	7	hSpCas9	negative selection	12200791
68014090	68014113	10	-	28162770	OCIAML2	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.7655683956193171	[25]	[244]	7	hSpCas9	negative selection	12200792
68014035	68014058	10	+	28162770	OCIAML2	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	0.6030798609408482	[30]	[260]	6	hSpCas9	negative selection	12200793
67954701	67954724	10	-	28162770	OCIAML3	viability	GAAGATGCTGTGGATGCAGGAGG	HERC4	ENSG00000148634	-0.1365348747249228	[66]	[183]	-1	hSpCas9	negative selection	12370150
67990239	67990262	10	+	28162770	OCIAML3	viability	GTTCACAAGAGCTGTACCAAAGG	HERC4	ENSG00000148634	1.0791074913046943	[81]	[522]	8	hSpCas9	negative selection	12370151
68025596	68025619	10	-	28162770	OCIAML3	viability	CCAGTCATGAAATAAACCCAAGG	HERC4	ENSG00000148634	0.07869775503865928	[100]	[321]	0	hSpCas9	negative selection	12370152
67992292	67992315	10	+	28162770	OCIAML3	viability	GGACATCTGAAGTCATCTGGTGG	HERC4	ENSG00000148634	0.5719042986115256	[79]	[358]	5	hSpCas9	negative selection	12370153
67955043	67955066	10	-	28162770	OCIAML3	viability	GAATCCCTGCTTAATTCTAGTGG	HERC4	ENSG00000148634	0.29676328992107837	[23]	[88]	3	hSpCas9	negative selection	12370154
67932638	67932661	10	-	28162770	OCIAML3	viability	GCCTAATGAACTACAAGCAATGG	HERC4	ENSG00000148634	0.7279204545631993	[16]	[84]	6	hSpCas9	negative selection	12370155
68044423	68044446	10	-	28162770	OCIAML3	viability	GCTTGGCCTGGTAGGATCAGAGG	HERC4	ENSG00000148634	1.127527913272437	[93]	[619]	8	hSpCas9	negative selection	12370156
68014142	68014165	10	+	28162770	OCIAML3	viability	GAGTAAATTCGTCCTGATGAAGG	HERC4	ENSG00000148634	0.9580902264913664	[147]	[867]	8	hSpCas9	negative selection	12370157
68014090	68014113	10	-	28162770	OCIAML3	viability	GAACCGGTTCAACAAGCAACAGG	HERC4	ENSG00000148634	0.3832722831757531	[79]	[314]	3	hSpCas9	negative selection	12370158
68014035	68014058	10	+	28162770	OCIAML3	viability	GTAGACACTGCCCATTATAGGGG	HERC4	ENSG00000148634	1.405992359675837	[34]	[279]	9	hSpCas9	negative selection	12370159