Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:51191
• Symbol:HERC5
• Description:HECT and RLD domain containing E3 ubiquitin protein ligase 5

DataSource: http://genomecrispr.dkfz.de/#!/results/HERC5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
88457259	88457282	4	+	26472758	Jiyoye	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.8546343584770947	[54]	[74]	6	hSpCas9	negative selection	70246
88462150	88462173	4	+	26472758	Jiyoye	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	-0.5599599845884999	[216]	[110]	-4	hSpCas9	negative selection	70247
88469224	88469247	4	+	26472758	Jiyoye	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	1.6938526292101836	[115]	[282]	8	hSpCas9	negative selection	70248
88457277	88457300	4	+	26472758	Jiyoye	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-0.8620112513095156	[93]	[38]	-6	hSpCas9	negative selection	70249
88457456	88457479	4	+	26472758	Jiyoye	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.027887907176231463	[185]	[142]	0	hSpCas9	negative selection	70250
88462323	88462346	4	+	26472758	Jiyoye	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	1.4616231655282497	[38]	[80]	8	hSpCas9	negative selection	70251
88467162	88467185	4	-	26472758	Jiyoye	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	-1.3036960165091884	[346]	[105]	-7	hSpCas9	negative selection	70252
88457430	88457453	4	+	26472758	Jiyoye	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	2.1727101278688505	[4]	[16]	9	hSpCas9	negative selection	70253
88462212	88462235	4	-	26472758	Jiyoye	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	1.0628408735702313	[218]	[344]	7	hSpCas9	negative selection	70254
88463960	88463983	4	+	26472758	Jiyoye	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	-0.5928246184941266	[317]	[158]	-4	hSpCas9	negative selection	70255
88457259	88457282	4	+	26472758	KBM7	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.17165091802712654	[393,319]	[244,136]	1	hSpCas9	negative selection	261364
88462150	88462173	4	+	26472758	KBM7	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.35761592546848786	[689,714]	[594,274]	4	hSpCas9	negative selection	261365
88469224	88469247	4	+	26472758	KBM7	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	1.5564620860998548	[1241,708]	[2328,413]	9	hSpCas9	negative selection	261366
88457277	88457300	4	+	26472758	KBM7	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.6073412064809858	[440,257]	[47,56]	-8	hSpCas9	negative selection	261367
88457456	88457479	4	+	26472758	KBM7	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.028373765057916833	[748,440]	[279,257]	0	hSpCas9	negative selection	261368
88462323	88462346	4	+	26472758	KBM7	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.4636759410547898	[347,238]	[241,138]	5	hSpCas9	negative selection	261369
88467162	88467185	4	-	26472758	KBM7	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.23640805796691733	[895,738]	[401,493]	2	hSpCas9	negative selection	261370
88457430	88457453	4	+	26472758	KBM7	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.7631292174356921	[207,165]	[190,109]	8	hSpCas9	negative selection	261371
88462212	88462235	4	-	26472758	KBM7	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.23730092716574958	[1164,1005]	[598,600]	2	hSpCas9	negative selection	261372
88463960	88463983	4	+	26472758	KBM7	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.18196423790195215	[1192,1107]	[456,754]	1	hSpCas9	negative selection	261373
88457259	88457282	4	+	26472758	Raji	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.4596852793044809	[140]	[44]	4	hSpCas9	negative selection	452482
88462150	88462173	4	+	26472758	Raji	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.3825833221843249	[432]	[130]	3	hSpCas9	negative selection	452483
88469224	88469247	4	+	26472758	Raji	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	1.5249410266309589	[285]	[190]	9	hSpCas9	negative selection	452484
88457277	88457300	4	+	26472758	Raji	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.2230061382619588	[170]	[16]	-7	hSpCas9	negative selection	452485
88457456	88457479	4	+	26472758	Raji	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.7817130388004203	[192]	[76]	7	hSpCas9	negative selection	452486
88462323	88462346	4	+	26472758	Raji	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.0957955610983876	[124]	[30]	0	hSpCas9	negative selection	452487
88467162	88467185	4	-	26472758	Raji	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.542126444000002	[508]	[171]	5	hSpCas9	negative selection	452488
88457430	88457453	4	+	26472758	Raji	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-0.6321560024564332	[186]	[27]	-5	hSpCas9	negative selection	452489
88462212	88462235	4	-	26472758	Raji	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.24201220920334765	[684]	[187]	2	hSpCas9	negative selection	452490
88463960	88463983	4	+	26472758	Raji	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.18370449534876365	[496]	[130]	1	hSpCas9	negative selection	452491
88457259	88457282	4	+	26472758	K562	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.38965444522241777	[405]	[448]	3	hSpCas9	negative selection	643600
88462150	88462173	4	+	26472758	K562	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	-0.32954477410545246	[587]	[394]	-2	hSpCas9	negative selection	643601
88469224	88469247	4	+	26472758	K562	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.5952651687595192	[809]	[1032]	5	hSpCas9	negative selection	643602
88457277	88457300	4	+	26472758	K562	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.0659213929457036	[309]	[124]	-5	hSpCas9	negative selection	643603
88457456	88457479	4	+	26472758	K562	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.6414597976514448	[362]	[477]	5	hSpCas9	negative selection	643604
88462323	88462346	4	+	26472758	K562	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.6213881861117712	[287]	[373]	5	hSpCas9	negative selection	643605
88467162	88467185	4	-	26472758	K562	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	-0.0027326365606916703	[812]	[684]	0	hSpCas9	negative selection	643606
88457430	88457453	4	+	26472758	K562	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.8012889213582501	[120]	[177]	6	hSpCas9	negative selection	643607
88462212	88462235	4	-	26472758	K562	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.39322243273036617	[947]	[1050]	3	hSpCas9	negative selection	643608
88463960	88463983	4	+	26472758	K562	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.6452638797780306	[995]	[1314]	5	hSpCas9	negative selection	643609
88457456	88457479	4	+	26627737	DLD1	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.669328638008202	[579]	[159,118,69]	-6	hSpCas9	negative selection	826196
88459373	88459396	4	+	26627737	DLD1	viability	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.366575371367361	[411]	[186,212,108]	4	hSpCas9	negative selection	826197
88462322	88462345	4	+	26627737	DLD1	viability	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.537159929948694	[489]	[150,237,270]	5	hSpCas9	negative selection	826198
88463602	88463625	4	+	26627737	DLD1	viability	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.26750553745961736	[1681]	[547,423,350]	-3	hSpCas9	negative selection	826199
88467152	88467175	4	-	26627737	DLD1	viability	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	1.060881782246386	[299]	[267,203,125]	8	hSpCas9	negative selection	826200
88469224	88469247	4	+	26627737	DLD1	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.21712356484227469	[1204]	[350,565,406]	2	hSpCas9	negative selection	826201
88457456	88457479	4	+	26627737	GBM cells	viability after 5 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.18774050736849646	[222]	[134,74]	-3	hSpCas9	negative selection	908511
88459373	88459396	4	+	26627737	GBM cells	viability after 5 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.053191435010003035	[236]	[99,144]	-1	hSpCas9	negative selection	908512
88462322	88462345	4	+	26627737	GBM cells	viability after 5 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.6247389114466914	[233]	[201,184]	8	hSpCas9	negative selection	908513
88463602	88463625	4	+	26627737	GBM cells	viability after 5 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.5805364352081168	[557]	[455,438]	8	hSpCas9	negative selection	908514
88467152	88467175	4	-	26627737	GBM cells	viability after 5 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.37971738599912697	[278]	[115,113]	-5	hSpCas9	negative selection	908515
88469224	88469247	4	+	26627737	GBM cells	viability after 5 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.23555804093845922	[617]	[286,275]	-4	hSpCas9	negative selection	908516
88457456	88457479	4	+	26627737	GBM cells	viability after 13 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.22009210957151265	[222]	[131,80]	-3	hSpCas9	negative selection	990826
88459373	88459396	4	+	26627737	GBM cells	viability after 13 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.0795593699882087	[236]	[124,118]	-1	hSpCas9	negative selection	990827
88462322	88462345	4	+	26627737	GBM cells	viability after 13 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.3678666749982953	[233]	[186,144]	5	hSpCas9	negative selection	990828
88463602	88463625	4	+	26627737	GBM cells	viability after 13 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.5952850904166593	[557]	[570,364]	7	hSpCas9	negative selection	990829
88467152	88467175	4	-	26627737	GBM cells	viability after 13 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.5559296830725753	[278]	[113,93]	-6	hSpCas9	negative selection	990830
88469224	88469247	4	+	26627737	GBM cells	viability after 13 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.20670995785829915	[617]	[364,229]	-2	hSpCas9	negative selection	990831
88457456	88457479	4	+	26627737	GBM cells	viability after 21 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.6826865577859575	[222]	[75,74]	-6	hSpCas9	negative selection	1073141
88459373	88459396	4	+	26627737	GBM cells	viability after 21 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.8130160343256501	[236]	[232,219]	7	hSpCas9	negative selection	1073142
88462322	88462345	4	+	26627737	GBM cells	viability after 21 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.34386867232698604	[233]	[164,157]	3	hSpCas9	negative selection	1073143
88463602	88463625	4	+	26627737	GBM cells	viability after 21 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.6691676001695457	[557]	[515,450]	6	hSpCas9	negative selection	1073144
88467152	88467175	4	-	26627737	GBM cells	viability after 21 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.1267932939776903	[278]	[142,134]	-1	hSpCas9	negative selection	1073145
88469224	88469247	4	+	26627737	GBM cells	viability after 21 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.10798700203243494	[617]	[345,279]	-1	hSpCas9	negative selection	1073146
88457456	88457479	4	+	26627737	RPE1	viability after 9 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.12452076009168117	[517]	[71,311]	0	hSpCas9	negative selection	1155456
88459373	88459396	4	+	26627737	RPE1	viability after 9 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.5827115191769456	[1029]	[244,176]	-4	hSpCas9	negative selection	1155457
88462322	88462345	4	+	26627737	RPE1	viability after 9 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	-0.12737584506428246	[1212]	[303,403]	-1	hSpCas9	negative selection	1155458
88463602	88463625	4	+	26627737	RPE1	viability after 9 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.2967667575042181	[2615]	[774,526]	-2	hSpCas9	negative selection	1155459
88467152	88467175	4	-	26627737	RPE1	viability after 9 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.317612920422295	[735]	[97,296]	-2	hSpCas9	negative selection	1155460
88469224	88469247	4	+	26627737	RPE1	viability after 9 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-1.3418409050516127	[2695]	[294,381]	-7	hSpCas9	negative selection	1155461
88457456	88457479	4	+	26627737	RPE1	viability after 12 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.17234773101617534	[517]	[150,162]	1	hSpCas9	negative selection	1237771
88459373	88459396	4	+	26627737	RPE1	viability after 12 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.9751064710302254	[1029]	[149,130]	-6	hSpCas9	negative selection	1237772
88462322	88462345	4	+	26627737	RPE1	viability after 12 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.25547988129362376	[1212]	[338,441]	1	hSpCas9	negative selection	1237773
88463602	88463625	4	+	26627737	RPE1	viability after 12 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.42761483338905104	[2615]	[1125,753]	3	hSpCas9	negative selection	1237774
88467152	88467175	4	-	26627737	RPE1	viability after 12 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.09696059944723145	[735]	[163,206]	0	hSpCas9	negative selection	1237775
88469224	88469247	4	+	26627737	RPE1	viability after 12 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-1.1630626078049935	[2695]	[355,288]	-7	hSpCas9	negative selection	1237776
88457456	88457479	4	+	26627737	RPE1	viability after 15 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.1575062486081361	[517]	[53,205]	-1	hSpCas9	negative selection	1320086
88459373	88459396	4	+	26627737	RPE1	viability after 15 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.04113368945821505	[1029]	[413,156]	0	hSpCas9	negative selection	1320087
88462322	88462345	4	+	26627737	RPE1	viability after 15 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.5383697733159443	[1212]	[422,570]	3	hSpCas9	negative selection	1320088
88463602	88463625	4	+	26627737	RPE1	viability after 15 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.13625949719677388	[2615]	[795,829]	0	hSpCas9	negative selection	1320089
88467152	88467175	4	-	26627737	RPE1	viability after 15 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.7396367788827006	[735]	[85,161]	-5	hSpCas9	negative selection	1320090
88469224	88469247	4	+	26627737	RPE1	viability after 15 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.8274223309556958	[2695]	[554,308]	-5	hSpCas9	negative selection	1320091
88457456	88457479	4	+	26627737	RPE1	viability after 18 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.4188034620041558	[517]	[124,252]	2	hSpCas9	negative selection	1402401
88459373	88459396	4	+	26627737	RPE1	viability after 18 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.4858512809644636	[1029]	[270,120]	-3	hSpCas9	negative selection	1402402
88462322	88462345	4	+	26627737	RPE1	viability after 18 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	-0.15849262010241405	[1212]	[228,361]	-1	hSpCas9	negative selection	1402403
88463602	88463625	4	+	26627737	RPE1	viability after 18 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.33997161267953646	[2615]	[720,1077]	2	hSpCas9	negative selection	1402404
88467152	88467175	4	-	26627737	RPE1	viability after 18 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.10754743765536273	[735]	[150,219]	0	hSpCas9	negative selection	1402405
88469224	88469247	4	+	26627737	RPE1	viability after 18 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-1.1292428255771072	[2695]	[466,188]	-6	hSpCas9	negative selection	1402406
88457456	88457479	4	+	26627737	HeLa	viability after 8 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.02540440168859419	[413]	[350,97,140]	0	hSpCas9	negative selection	1484716
88459373	88459396	4	+	26627737	HeLa	viability after 8 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.7079043910678668	[83]	[71,37,70]	6	hSpCas9	negative selection	1484717
88462322	88462345	4	+	26627737	HeLa	viability after 8 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	1.9924635638478876	[178]	[262,309,343]	9	hSpCas9	negative selection	1484718
88463602	88463625	4	+	26627737	HeLa	viability after 8 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.4616453808842772	[1076]	[211,296,473]	-4	hSpCas9	negative selection	1484719
88467152	88467175	4	-	26627737	HeLa	viability after 8 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.7130454930730266	[194]	[197,133,100]	6	hSpCas9	negative selection	1484720
88469224	88469247	4	+	26627737	HeLa	viability after 8 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.04819151543233868	[1051]	[367,519,424]	0	hSpCas9	negative selection	1484721
88457456	88457479	4	+	26627737	HeLa	viability after 12 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.01611710436390773	[413]	[168,143,208]	0	hSpCas9	negative selection	1567031
88459373	88459396	4	+	26627737	HeLa	viability after 12 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	2.2764331715995225	[83]	[192,132,182]	9	hSpCas9	negative selection	1567032
88462322	88462345	4	+	26627737	HeLa	viability after 12 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	1.4921500598751627	[178]	[69,238,307]	8	hSpCas9	negative selection	1567033
88463602	88463625	4	+	26627737	HeLa	viability after 12 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.021630177640770354	[1076]	[392,306,627]	0	hSpCas9	negative selection	1567034
88467152	88467175	4	-	26627737	HeLa	viability after 12 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	1.1295929144997754	[194]	[156,198,169]	7	hSpCas9	negative selection	1567035
88469224	88469247	4	+	26627737	HeLa	viability after 12 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.2540008712753188	[1051]	[302,344,445]	-2	hSpCas9	negative selection	1567036
88457456	88457479	4	+	26627737	HeLa	viability after 15 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.4229008472065608	[413]	[125,195,367]	3	hSpCas9	negative selection	1649346
88459373	88459396	4	+	26627737	HeLa	viability after 15 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	2.1322355102572264	[83]	[157,64,232]	9	hSpCas9	negative selection	1649347
88462322	88462345	4	+	26627737	HeLa	viability after 15 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	1.9508255849513776	[178]	[117,329,408]	9	hSpCas9	negative selection	1649348
88463602	88463625	4	+	26627737	HeLa	viability after 15 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.5189440372046185	[1076]	[245,278,400]	-4	hSpCas9	negative selection	1649349
88467152	88467175	4	-	26627737	HeLa	viability after 15 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.9045025147576338	[194]	[147,158,137]	6	hSpCas9	negative selection	1649350
88469224	88469247	4	+	26627737	HeLa	viability after 15 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.6859077516093999	[1051]	[219,291,288]	-6	hSpCas9	negative selection	1649351
88457456	88457479	4	+	26627737	HeLa	viability after 18 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.4229785415541252	[413]	[83,162,367]	3	hSpCas9	negative selection	1731661
88459373	88459396	4	+	26627737	HeLa	viability after 18 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	2.1805433880695193	[83]	[114,54,232]	9	hSpCas9	negative selection	1731662
88462322	88462345	4	+	26627737	HeLa	viability after 18 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	1.9487892606902117	[178]	[76,274,408]	9	hSpCas9	negative selection	1731663
88463602	88463625	4	+	26627737	HeLa	viability after 18 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.504649370180469	[1076]	[166,235,400]	-4	hSpCas9	negative selection	1731664
88467152	88467175	4	-	26627737	HeLa	viability after 18 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.9182716874868561	[194]	[104,127,137]	7	hSpCas9	negative selection	1731665
88469224	88469247	4	+	26627737	HeLa	viability after 18 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.6546001373068598	[1051]	[157,242,288]	-5	hSpCas9	negative selection	1731666
88457456	88457479	4	+	26627737	HCT116	viability after 6 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.907792561902911	[174]	[33,3]	-5	hSpCas9	negative selection	1813976
88459373	88459396	4	+	26627737	HCT116	viability after 6 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.647380251490818	[613]	[214,115]	3	hSpCas9	negative selection	1813977
88462322	88462345	4	+	26627737	HCT116	viability after 6 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	2.1126032570174944	[713]	[293,590]	8	hSpCas9	negative selection	1813978
88463602	88463625	4	+	26627737	HCT116	viability after 6 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.2933207847242685	[1345]	[413,173]	1	hSpCas9	negative selection	1813979
88467152	88467175	4	-	26627737	HCT116	viability after 6 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.3365225608218878	[589]	[144,33]	-2	hSpCas9	negative selection	1813980
88469224	88469247	4	+	26627737	HCT116	viability after 6 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.21321396394149428	[1859]	[483,258]	1	hSpCas9	negative selection	1813981
88457456	88457479	4	+	26627737	HCT116	viability after 8 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.47547964399300746	[268]	[115,97,105]	-5	hSpCas9	negative selection	1896291
88459373	88459396	4	+	26627737	HCT116	viability after 8 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.6756584858435111	[144]	[157,145,79]	6	hSpCas9	negative selection	1896292
88462322	88462345	4	+	26627737	HCT116	viability after 8 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	1.896755882388251	[68]	[152,134,136]	9	hSpCas9	negative selection	1896293
88463602	88463625	4	+	26627737	HCT116	viability after 8 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.38818762157768605	[594]	[366,559,359]	4	hSpCas9	negative selection	1896294
88467152	88467175	4	-	26627737	HCT116	viability after 8 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.7914175165464095	[178]	[212,137,161]	7	hSpCas9	negative selection	1896295
88469224	88469247	4	+	26627737	HCT116	viability after 8 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.3220659158329253	[842]	[386,355,371]	-4	hSpCas9	negative selection	1896296
88457456	88457479	4	+	26627737	HCT116	viability after 9 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	2.5913929910580604	[174]	[413,176]	9	hSpCas9	negative selection	1978606
88459373	88459396	4	+	26627737	HCT116	viability after 9 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.43097394788070503	[613]	[153,273]	3	hSpCas9	negative selection	1978607
88462322	88462345	4	+	26627737	HCT116	viability after 9 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.20053064174225996	[713]	[265,181]	1	hSpCas9	negative selection	1978608
88463602	88463625	4	+	26627737	HCT116	viability after 9 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.29834145679062996	[1345]	[446,437]	2	hSpCas9	negative selection	1978609
88467152	88467175	4	-	26627737	HCT116	viability after 9 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.08198380537380656	[589]	[178,124]	0	hSpCas9	negative selection	1978610
88469224	88469247	4	+	26627737	HCT116	viability after 9 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.9154988298642274	[1859]	[412,144]	-6	hSpCas9	negative selection	1978611
88457456	88457479	4	+	26627737	HCT116	viability after 12 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.1968253050407618	[268]	[91,151,247]	2	hSpCas9	negative selection	2060921
88459373	88459396	4	+	26627737	HCT116	viability after 12 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	1.3601463509292593	[144]	[186,252,148]	9	hSpCas9	negative selection	2060922
88462322	88462345	4	+	26627737	HCT116	viability after 12 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	2.1863665919941786	[68]	[187,159,144]	9	hSpCas9	negative selection	2060923
88463602	88463625	4	+	26627737	HCT116	viability after 12 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.4161343608099288	[594]	[474,514,258]	4	hSpCas9	negative selection	2060924
88467152	88467175	4	-	26627737	HCT116	viability after 12 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.1424474668426835	[178]	[141,97,67]	1	hSpCas9	negative selection	2060925
88469224	88469247	4	+	26627737	HCT116	viability after 12 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.7404062795942656	[842]	[191,307,302]	-7	hSpCas9	negative selection	2060926
88457456	88457479	4	+	26627737	HCT116	viability after 15 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.4380163479243987	[268]	[106,99,133]	-4	hSpCas9	negative selection	2143236
88459373	88459396	4	+	26627737	HCT116	viability after 15 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.880929116790666	[144]	[123,221,110]	7	hSpCas9	negative selection	2143237
88462322	88462345	4	+	26627737	HCT116	viability after 15 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	2.015007270723804	[68]	[139,174,162]	9	hSpCas9	negative selection	2143238
88463602	88463625	4	+	26627737	HCT116	viability after 15 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.265466435066368	[594]	[408,494,328]	2	hSpCas9	negative selection	2143239
88467152	88467175	4	-	26627737	HCT116	viability after 15 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.34397765275441067	[178]	[184,159,53]	3	hSpCas9	negative selection	2143240
88469224	88469247	4	+	26627737	HCT116	viability after 15 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.39749605548722244	[842]	[503,477,139]	-4	hSpCas9	negative selection	2143241
88457456	88457479	4	+	26627737	HCT116	viability after 18 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.666252668634683	[268]	[95,91,55]	-6	hSpCas9	negative selection	2225551
88459373	88459396	4	+	26627737	HCT116	viability after 18 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	1.1915240159136324	[144]	[171,97,216]	8	hSpCas9	negative selection	2225552
88462322	88462345	4	+	26627737	HCT116	viability after 18 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	2.6052946754147017	[68]	[82,251,273]	9	hSpCas9	negative selection	2225553
88463602	88463625	4	+	26627737	HCT116	viability after 18 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.30267117069748184	[594]	[362,371,326]	2	hSpCas9	negative selection	2225554
88467152	88467175	4	-	26627737	HCT116	viability after 18 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.45253766890866676	[178]	[154,5,30]	-4	hSpCas9	negative selection	2225555
88469224	88469247	4	+	26627737	HCT116	viability after 18 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.06684941434610492	[842]	[427,426,305]	0	hSpCas9	negative selection	2225556
88457256	88457279	4	+	24336569	HL60	viability	CCCGCAAAGCGGCGATGGAGCGG	HERC5	ENSG00000138646	0.8358636634538394	[403]	[1525]	6	hSpCas9	negative selection	2269424
88457265	88457288	4	+	24336569	HL60	viability	CGGCGATGGAGCGGAGGTCGCGG	HERC5	ENSG00000138646	0.46858450305110555	[236]	[693]	4	hSpCas9	negative selection	2269425
88457277	88457300	4	+	24336569	HL60	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.3685217356692063	[653]	[535]	-8	hSpCas9	negative selection	2269426
88457285	88457308	4	+	24336569	HL60	viability	CGGAGGAAGTCGCGGCGCAACGG	HERC5	ENSG00000138646	-0.2969491549294033	[381]	[657]	-3	hSpCas9	negative selection	2269427
88457299	88457322	4	+	24336569	HL60	viability	GCGCAACGGGCGCTCGACCGCGG	HERC5	ENSG00000138646	-2.9135194633148247	[323]	[90]	-9	hSpCas9	negative selection	2269428
88457328	88457351	4	-	24336569	HL60	viability	CTTCGCGGGCTGGGTCGCGGCGG	HERC5	ENSG00000138646	-0.5189389890274956	[215]	[318]	-5	hSpCas9	negative selection	2269429
88457335	88457358	4	+	24336569	HL60	viability	GACCCAGCCCGCGAAGTCTCCGG	HERC5	ENSG00000138646	0.13295282005943626	[595]	[1382]	1	hSpCas9	negative selection	2269430
88457342	88457365	4	-	24336569	HL60	viability	TGTGCGCCCGGAGACTTCGCGGG	HERC5	ENSG00000138646	0.07646078682939095	[777]	[1735]	0	hSpCas9	negative selection	2269431
88457349	88457372	4	+	24336569	HL60	viability	AGTCTCCGGGCGCACAGCTCTGG	HERC5	ENSG00000138646	1.0902085630996832	[274]	[1238]	8	hSpCas9	negative selection	2269432
88457354	88457377	4	-	24336569	HL60	viability	AAGAGCCAGAGCTGTGCGCCCGG	HERC5	ENSG00000138646	-0.1463276017393973	[670]	[1282]	-1	hSpCas9	negative selection	2269433
88457256	88457279	4	+	24336569	KBM7	viability	CCCGCAAAGCGGCGATGGAGCGG	HERC5	ENSG00000138646	0.811715936570189	[498]	[2388]	7	hSpCas9	negative selection	2336601
88457265	88457288	4	+	24336569	KBM7	viability	CGGCGATGGAGCGGAGGTCGCGG	HERC5	ENSG00000138646	0.30516939485825123	[199]	[673]	3	hSpCas9	negative selection	2336602
88457277	88457300	4	+	24336569	KBM7	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-3.3071640773790447	[449]	[123]	-9	hSpCas9	negative selection	2336603
88457285	88457308	4	+	24336569	KBM7	viability	CGGAGGAAGTCGCGGCGCAACGG	HERC5	ENSG00000138646	0.7559961943353469	[225]	[1040]	6	hSpCas9	negative selection	2336604
88457299	88457322	4	+	24336569	KBM7	viability	GCGCAACGGGCGCTCGACCGCGG	HERC5	ENSG00000138646	0.4407754476222083	[140]	[521]	4	hSpCas9	negative selection	2336605
88457328	88457351	4	-	24336569	KBM7	viability	CTTCGCGGGCTGGGTCGCGGCGG	HERC5	ENSG00000138646	-0.5714918002343589	[242]	[445]	-4	hSpCas9	negative selection	2336606
88457335	88457358	4	+	24336569	KBM7	viability	GACCCAGCCCGCGAAGTCTCCGG	HERC5	ENSG00000138646	-1.0728591524575268	[380]	[493]	-7	hSpCas9	negative selection	2336607
88457342	88457365	4	-	24336569	KBM7	viability	TGTGCGCCCGGAGACTTCGCGGG	HERC5	ENSG00000138646	0.9355490547752174	[659]	[3442]	7	hSpCas9	negative selection	2336608
88457349	88457372	4	+	24336569	KBM7	viability	AGTCTCCGGGCGCACAGCTCTGG	HERC5	ENSG00000138646	0.48725575678466115	[316]	[1211]	4	hSpCas9	negative selection	2336609
88457354	88457377	4	-	24336569	KBM7	viability	AAGAGCCAGAGCTGTGCGCCCGG	HERC5	ENSG00000138646	0.7285412645218537	[567]	[2566]	6	hSpCas9	negative selection	2336610
88477270	88477293	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAAGGGGAAGGGAAGGGGAAGG	HERC5	ENSG00000138646	-0.6223964853463964	[2,56]	[2,4]	-3	dCas9-VP64	positive selection	2383875
88473090	88473113	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTCTCGCTTTGTTGCCCAGG	HERC5	ENSG00000138646	-0.201832538798	[0,8]	[0,0]	-1	dCas9-VP64	positive selection	2389428
88465085	88465108	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTATTTTTAGTAGAGTCGGGG	HERC5	ENSG00000138646	1.0128281800924883	[250,40]	[67,58]	4	dCas9-VP64	positive selection	2417021
88477225	88477248	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGAAGGAAGGGAGGGGAGGGG	HERC5	ENSG00000138646	1.6344311854072724	[4,76]	[3,53]	6	dCas9-VP64	positive selection	2467432
88477270	88477293	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAAGGGGAAGGGAAGGGGAAGG	HERC5	ENSG00000138646	-0.3491485104501326	[71,17]	[13,8]	-4	dCas9-VP64	positive selection	2479130
88473090	88473113	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTCTCGCTTTGTTGCCCAGG	HERC5	ENSG00000138646	0.4706754367327671	[71,48]	[9,42]	3	dCas9-VP64	positive selection	2484683
88465085	88465108	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTATTTTTAGTAGAGTCGGGG	HERC5	ENSG00000138646	-0.03815698815020019	[56,33]	[21,6]	0	dCas9-VP64	positive selection	2512276
88477225	88477248	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGAAGGAAGGGAGGGGAGGGG	HERC5	ENSG00000138646	3.2323029195494195	[316,94]	[63,1177]	9	dCas9-VP64	positive selection	2562687
88457256	88457279	4	+	27260157	DLD1	viability	CCCGCAAAGCGGCGATGGAGCGG	HERC5	ENSG00000138646	-0.0840038118240173	[]	[]	0	hSpCas9	negative selection	2574498
88457447	88457470	4	-	27260157	DLD1	viability	TCCAAGACCGCGAGGCGCCCCGG	HERC5	ENSG00000138646	-0.603814510254025	[]	[]	-5	hSpCas9	negative selection	2574905
88457265	88457288	4	+	27260157	DLD1	viability	CGGCGATGGAGCGGAGGTCGCGG	HERC5	ENSG00000138646	0.361938329369599	[]	[]	4	hSpCas9	negative selection	2577040
88457453	88457476	4	+	27260157	DLD1	viability	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	-0.14668749890441	[]	[]	-1	hSpCas9	negative selection	2577378
88457268	88457291	4	+	27260157	DLD1	viability	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	-0.366161670053254	[]	[]	-3	hSpCas9	negative selection	2577469
88457349	88457372	4	+	27260157	DLD1	viability	AGTCTCCGGGCGCACAGCTCTGG	HERC5	ENSG00000138646	0.29256717865071	[]	[]	4	hSpCas9	negative selection	2578997
88463576	88463599	4	+	27260157	DLD1	viability	GTTGAATTTGTCGCTTGTGGTGG	HERC5	ENSG00000138646	-0.766432338363029	[]	[]	-5	hSpCas9	negative selection	2580954
88462163	88462186	4	-	27260157	DLD1	viability	CAACTCCAAGCTGCCCATGCAGG	HERC5	ENSG00000138646	-0.13516695666577	[]	[]	-1	hSpCas9	negative selection	2587612
88457285	88457308	4	+	27260157	DLD1	viability	CGGAGGAAGTCGCGGCGCAACGG	HERC5	ENSG00000138646	0.701087776734703	[]	[]	8	hSpCas9	negative selection	2609598
88457342	88457365	4	-	27260157	DLD1	viability	TGTGCGCCCGGAGACTTCGCGGG	HERC5	ENSG00000138646	-0.2125888256906	[]	[]	-1	hSpCas9	negative selection	2612535
88457299	88457322	4	+	27260157	DLD1	viability	GCGCAACGGGCGCTCGACCGCGG	HERC5	ENSG00000138646	0.122040508397238	[]	[]	3	hSpCas9	negative selection	2614490
88462207	88462230	4	-	27260157	DLD1	viability	GTGCTCCACAATCTGTGGTGTGG	HERC5	ENSG00000138646	-0.306830981632054	[]	[]	-3	hSpCas9	negative selection	2616233
88457328	88457351	4	-	27260157	DLD1	viability	CTTCGCGGGCTGGGTCGCGGCGG	HERC5	ENSG00000138646	-0.966498931111528	[]	[]	-7	hSpCas9	negative selection	2616725
88457277	88457300	4	+	27260157	DLD1	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.97215353362298	[]	[]	-8	hSpCas9	negative selection	2619608
88457354	88457377	4	-	27260157	DLD1	viability	AAGAGCCAGAGCTGTGCGCCCGG	HERC5	ENSG00000138646	-0.413244849449899	[]	[]	-3	hSpCas9	negative selection	2620402
88457255	88457278	4	-	27260157	DLD1	viability	CGCTCCATCGCCGCTTTGCGGGG	HERC5	ENSG00000138646	0.646042687604738	[]	[]	8	hSpCas9	negative selection	2620551
88462322	88462345	4	+	27260157	DLD1	viability	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.185062651822065	[]	[]	3	hSpCas9	negative selection	2640761
88457335	88457358	4	+	27260157	DLD1	viability	GACCCAGCCCGCGAAGTCTCCGG	HERC5	ENSG00000138646	0.0612010502539835	[]	[]	3	hSpCas9	negative selection	2644144
88457331	88457354	4	-	27260157	DLD1	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-2.56182402240741	[]	[]	-9	hSpCas9	negative selection	2649349
88457256	88457279	4	+	27260157	HT1080	viability	CCCGCAAAGCGGCGATGGAGCGG	HERC5	ENSG00000138646	-0.724079527922153	[]	[]	-8	hSpCas9	negative selection	2650628
88457447	88457470	4	-	27260157	HT1080	viability	TCCAAGACCGCGAGGCGCCCCGG	HERC5	ENSG00000138646	0.0128326377089232	[]	[]	0	hSpCas9	negative selection	2651035
88457265	88457288	4	+	27260157	HT1080	viability	CGGCGATGGAGCGGAGGTCGCGG	HERC5	ENSG00000138646	0.757527653877452	[]	[]	6	hSpCas9	negative selection	2653170
88457453	88457476	4	+	27260157	HT1080	viability	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	0.23962384503535	[]	[]	2	hSpCas9	negative selection	2653508
88457268	88457291	4	+	27260157	HT1080	viability	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	-0.482007284690864	[]	[]	-7	hSpCas9	negative selection	2653599
88457349	88457372	4	+	27260157	HT1080	viability	AGTCTCCGGGCGCACAGCTCTGG	HERC5	ENSG00000138646	0.204221100034568	[]	[]	2	hSpCas9	negative selection	2655127
88463576	88463599	4	+	27260157	HT1080	viability	GTTGAATTTGTCGCTTGTGGTGG	HERC5	ENSG00000138646	-0.0524491225587314	[]	[]	0	hSpCas9	negative selection	2657084
88462163	88462186	4	-	27260157	HT1080	viability	CAACTCCAAGCTGCCCATGCAGG	HERC5	ENSG00000138646	0.112067472967315	[]	[]	1	hSpCas9	negative selection	2663742
88457285	88457308	4	+	27260157	HT1080	viability	CGGAGGAAGTCGCGGCGCAACGG	HERC5	ENSG00000138646	1.17526954619265	[]	[]	8	hSpCas9	negative selection	2685728
88457342	88457365	4	-	27260157	HT1080	viability	TGTGCGCCCGGAGACTTCGCGGG	HERC5	ENSG00000138646	0.708475505809335	[]	[]	6	hSpCas9	negative selection	2688665
88457299	88457322	4	+	27260157	HT1080	viability	GCGCAACGGGCGCTCGACCGCGG	HERC5	ENSG00000138646	-0.542307410636349	[]	[]	-7	hSpCas9	negative selection	2690620
88462207	88462230	4	-	27260157	HT1080	viability	GTGCTCCACAATCTGTGGTGTGG	HERC5	ENSG00000138646	-0.115584881661752	[]	[]	0	hSpCas9	negative selection	2692363
88457328	88457351	4	-	27260157	HT1080	viability	CTTCGCGGGCTGGGTCGCGGCGG	HERC5	ENSG00000138646	-1.95833528506335	[]	[]	-9	hSpCas9	negative selection	2692855
88457277	88457300	4	+	27260157	HT1080	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.30004818079888	[]	[]	-9	hSpCas9	negative selection	2695738
88457354	88457377	4	-	27260157	HT1080	viability	AAGAGCCAGAGCTGTGCGCCCGG	HERC5	ENSG00000138646	0.329936800730694	[]	[]	3	hSpCas9	negative selection	2696532
88457255	88457278	4	-	27260157	HT1080	viability	CGCTCCATCGCCGCTTTGCGGGG	HERC5	ENSG00000138646	-0.685805898321187	[]	[]	-8	hSpCas9	negative selection	2696681
88462322	88462345	4	+	27260157	HT1080	viability	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.556506958475602	[]	[]	5	hSpCas9	negative selection	2716891
88457335	88457358	4	+	27260157	HT1080	viability	GACCCAGCCCGCGAAGTCTCCGG	HERC5	ENSG00000138646	1.70341560515402	[]	[]	9	hSpCas9	negative selection	2720274
88457331	88457354	4	-	27260157	HT1080	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-1.9994340077429	[]	[]	-9	hSpCas9	negative selection	2725479
88457256	88457279	4	+	27260157	MKN45	viability	CCCGCAAAGCGGCGATGGAGCGG	HERC5	ENSG00000138646	-0.874738400348872	[]	[]	-7	hSpCas9	negative selection	2726758
88457447	88457470	4	-	27260157	MKN45	viability	TCCAAGACCGCGAGGCGCCCCGG	HERC5	ENSG00000138646	-0.878830693703266	[]	[]	-7	hSpCas9	negative selection	2727165
88457265	88457288	4	+	27260157	MKN45	viability	CGGCGATGGAGCGGAGGTCGCGG	HERC5	ENSG00000138646	-0.189966586409444	[]	[]	0	hSpCas9	negative selection	2729300
88457453	88457476	4	+	27260157	MKN45	viability	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	0.659754639331257	[]	[]	7	hSpCas9	negative selection	2729638
88457268	88457291	4	+	27260157	MKN45	viability	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	-0.0637698484922467	[]	[]	0	hSpCas9	negative selection	2729729
88457349	88457372	4	+	27260157	MKN45	viability	AGTCTCCGGGCGCACAGCTCTGG	HERC5	ENSG00000138646	0.166110469159034	[]	[]	5	hSpCas9	negative selection	2731257
88463576	88463599	4	+	27260157	MKN45	viability	GTTGAATTTGTCGCTTGTGGTGG	HERC5	ENSG00000138646	-0.583916364110487	[]	[]	-6	hSpCas9	negative selection	2733214
88462163	88462186	4	-	27260157	MKN45	viability	CAACTCCAAGCTGCCCATGCAGG	HERC5	ENSG00000138646	0.124231172627584	[]	[]	4	hSpCas9	negative selection	2739872
88457285	88457308	4	+	27260157	MKN45	viability	CGGAGGAAGTCGCGGCGCAACGG	HERC5	ENSG00000138646	0.934692819078805	[]	[]	8	hSpCas9	negative selection	2761858
88457342	88457365	4	-	27260157	MKN45	viability	TGTGCGCCCGGAGACTTCGCGGG	HERC5	ENSG00000138646	0.239850446123119	[]	[]	5	hSpCas9	negative selection	2764795
88457299	88457322	4	+	27260157	MKN45	viability	GCGCAACGGGCGCTCGACCGCGG	HERC5	ENSG00000138646	-0.475646894572649	[]	[]	-6	hSpCas9	negative selection	2766750
88462207	88462230	4	-	27260157	MKN45	viability	GTGCTCCACAATCTGTGGTGTGG	HERC5	ENSG00000138646	0.258926980624064	[]	[]	5	hSpCas9	negative selection	2768493
88457328	88457351	4	-	27260157	MKN45	viability	CTTCGCGGGCTGGGTCGCGGCGG	HERC5	ENSG00000138646	-0.253905109235684	[]	[]	-1	hSpCas9	negative selection	2768985
88457277	88457300	4	+	27260157	MKN45	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.53747054570273	[]	[]	-9	hSpCas9	negative selection	2771868
88457354	88457377	4	-	27260157	MKN45	viability	AAGAGCCAGAGCTGTGCGCCCGG	HERC5	ENSG00000138646	-0.240502924158912	[]	[]	-1	hSpCas9	negative selection	2772662
88457255	88457278	4	-	27260157	MKN45	viability	CGCTCCATCGCCGCTTTGCGGGG	HERC5	ENSG00000138646	-0.00327935231187834	[]	[]	0	hSpCas9	negative selection	2772811
88462322	88462345	4	+	27260157	MKN45	viability	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.600582095516792	[]	[]	7	hSpCas9	negative selection	2793021
88457335	88457358	4	+	27260157	MKN45	viability	GACCCAGCCCGCGAAGTCTCCGG	HERC5	ENSG00000138646	1.25911664398494	[]	[]	9	hSpCas9	negative selection	2796404
88457331	88457354	4	-	27260157	MKN45	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-1.49689790364489	[]	[]	-8	hSpCas9	negative selection	2801609
88457256	88457279	4	+	27260157	RKO	viability	CCCGCAAAGCGGCGATGGAGCGG	HERC5	ENSG00000138646	-0.106854895424209	[]	[]	0	hSpCas9	negative selection	2802888
88457447	88457470	4	-	27260157	RKO	viability	TCCAAGACCGCGAGGCGCCCCGG	HERC5	ENSG00000138646	-1.06936641318392	[]	[]	-8	hSpCas9	negative selection	2803295
88457265	88457288	4	+	27260157	RKO	viability	CGGCGATGGAGCGGAGGTCGCGG	HERC5	ENSG00000138646	0.227436274218199	[]	[]	1	hSpCas9	negative selection	2805430
88457453	88457476	4	+	27260157	RKO	viability	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	-0.379885593599726	[]	[]	-6	hSpCas9	negative selection	2805768
88457268	88457291	4	+	27260157	RKO	viability	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	-0.571774629183766	[]	[]	-7	hSpCas9	negative selection	2805859
88457349	88457372	4	+	27260157	RKO	viability	AGTCTCCGGGCGCACAGCTCTGG	HERC5	ENSG00000138646	0.931584711134783	[]	[]	8	hSpCas9	negative selection	2807387
88463576	88463599	4	+	27260157	RKO	viability	GTTGAATTTGTCGCTTGTGGTGG	HERC5	ENSG00000138646	-0.0129560800405433	[]	[]	0	hSpCas9	negative selection	2809344
88462163	88462186	4	-	27260157	RKO	viability	CAACTCCAAGCTGCCCATGCAGG	HERC5	ENSG00000138646	-0.225499451583794	[]	[]	-1	hSpCas9	negative selection	2816002
88457285	88457308	4	+	27260157	RKO	viability	CGGAGGAAGTCGCGGCGCAACGG	HERC5	ENSG00000138646	0.488727367178133	[]	[]	2	hSpCas9	negative selection	2837988
88457342	88457365	4	-	27260157	RKO	viability	TGTGCGCCCGGAGACTTCGCGGG	HERC5	ENSG00000138646	-0.913569935349894	[]	[]	-8	hSpCas9	negative selection	2840925
88457299	88457322	4	+	27260157	RKO	viability	GCGCAACGGGCGCTCGACCGCGG	HERC5	ENSG00000138646	0.11941319168828	[]	[]	0	hSpCas9	negative selection	2842880
88462207	88462230	4	-	27260157	RKO	viability	GTGCTCCACAATCTGTGGTGTGG	HERC5	ENSG00000138646	0.292198538818787	[]	[]	1	hSpCas9	negative selection	2844623
88457328	88457351	4	-	27260157	RKO	viability	CTTCGCGGGCTGGGTCGCGGCGG	HERC5	ENSG00000138646	-0.542157650307055	[]	[]	-7	hSpCas9	negative selection	2845115
88457277	88457300	4	+	27260157	RKO	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-0.728685082083721	[]	[]	-7	hSpCas9	negative selection	2847998
88457354	88457377	4	-	27260157	RKO	viability	AAGAGCCAGAGCTGTGCGCCCGG	HERC5	ENSG00000138646	0.61452760361434	[]	[]	3	hSpCas9	negative selection	2848792
88457255	88457278	4	-	27260157	RKO	viability	CGCTCCATCGCCGCTTTGCGGGG	HERC5	ENSG00000138646	0.221832634518417	[]	[]	1	hSpCas9	negative selection	2848941
88462322	88462345	4	+	27260157	RKO	viability	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.989514111032629	[]	[]	9	hSpCas9	negative selection	2869151
88457335	88457358	4	+	27260157	RKO	viability	GACCCAGCCCGCGAAGTCTCCGG	HERC5	ENSG00000138646	0.795550019852015	[]	[]	8	hSpCas9	negative selection	2872534
88457331	88457354	4	-	27260157	RKO	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-1.99367920639174	[]	[]	-9	hSpCas9	negative selection	2877739
88457256	88457279	4	+	27260157	SF268	viability	CCCGCAAAGCGGCGATGGAGCGG	HERC5	ENSG00000138646	-1.23401668018171	[]	[]	-7	hSpCas9	negative selection	2879018
88457447	88457470	4	-	27260157	SF268	viability	TCCAAGACCGCGAGGCGCCCCGG	HERC5	ENSG00000138646	-0.331166992102311	[]	[]	-3	hSpCas9	negative selection	2879425
88457265	88457288	4	+	27260157	SF268	viability	CGGCGATGGAGCGGAGGTCGCGG	HERC5	ENSG00000138646	-0.272644053364298	[]	[]	-2	hSpCas9	negative selection	2881560
88457453	88457476	4	+	27260157	SF268	viability	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	-0.657454351708836	[]	[]	-5	hSpCas9	negative selection	2881898
88457268	88457291	4	+	27260157	SF268	viability	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	-0.529631814943628	[]	[]	-4	hSpCas9	negative selection	2881989
88457349	88457372	4	+	27260157	SF268	viability	AGTCTCCGGGCGCACAGCTCTGG	HERC5	ENSG00000138646	-0.283064432825878	[]	[]	-2	hSpCas9	negative selection	2883517
88463576	88463599	4	+	27260157	SF268	viability	GTTGAATTTGTCGCTTGTGGTGG	HERC5	ENSG00000138646	-1.62804574370267	[]	[]	-8	hSpCas9	negative selection	2885474
88462163	88462186	4	-	27260157	SF268	viability	CAACTCCAAGCTGCCCATGCAGG	HERC5	ENSG00000138646	-0.200384335313021	[]	[]	-1	hSpCas9	negative selection	2892132
88457285	88457308	4	+	27260157	SF268	viability	CGGAGGAAGTCGCGGCGCAACGG	HERC5	ENSG00000138646	0.446786632062804	[]	[]	7	hSpCas9	negative selection	2914118
88457342	88457365	4	-	27260157	SF268	viability	TGTGCGCCCGGAGACTTCGCGGG	HERC5	ENSG00000138646	-0.00181881812921159	[]	[]	0	hSpCas9	negative selection	2917055
88457299	88457322	4	+	27260157	SF268	viability	GCGCAACGGGCGCTCGACCGCGG	HERC5	ENSG00000138646	-0.37206182453436	[]	[]	-3	hSpCas9	negative selection	2919010
88462207	88462230	4	-	27260157	SF268	viability	GTGCTCCACAATCTGTGGTGTGG	HERC5	ENSG00000138646	0.279496446300221	[]	[]	4	hSpCas9	negative selection	2920753
88457328	88457351	4	-	27260157	SF268	viability	CTTCGCGGGCTGGGTCGCGGCGG	HERC5	ENSG00000138646	-1.50544486188887	[]	[]	-8	hSpCas9	negative selection	2921245
88457277	88457300	4	+	27260157	SF268	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-0.741656953955226	[]	[]	-5	hSpCas9	negative selection	2924128
88457354	88457377	4	-	27260157	SF268	viability	AAGAGCCAGAGCTGTGCGCCCGG	HERC5	ENSG00000138646	-0.361060184368389	[]	[]	-3	hSpCas9	negative selection	2924922
88457255	88457278	4	-	27260157	SF268	viability	CGCTCCATCGCCGCTTTGCGGGG	HERC5	ENSG00000138646	0.301889903675836	[]	[]	4	hSpCas9	negative selection	2925071
88462322	88462345	4	+	27260157	SF268	viability	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.887754043289343	[]	[]	9	hSpCas9	negative selection	2945281
88457335	88457358	4	+	27260157	SF268	viability	GACCCAGCCCGCGAAGTCTCCGG	HERC5	ENSG00000138646	0.651628172525121	[]	[]	8	hSpCas9	negative selection	2948664
88457331	88457354	4	-	27260157	SF268	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-3.24967551476619	[]	[]	-9	hSpCas9	negative selection	2953869
88463607	88463630	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGTGCCCTACTCACACAGGTGGG	HERC5	ENSG00000138646	0.18558582433359047	[3,3]	[3,2]	4	hSpCas9	positive selection	2993070
88457398	88457421	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACCCTCCGGAGCAGCGCGCGG	HERC5	ENSG00000138646	0.1942887755339125	[2,2]	[3,1]	4	hSpCas9	positive selection	2993071
88463872	88463895	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTCGGTGCTGGAAAACATGGG	HERC5	ENSG00000138646	0.08100277448340704	[3,3]	[4,2]	1	hSpCas9	positive selection	2993072
88457316	88457339	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCGCGGCGGCCTTGCCCGCGG	HERC5	ENSG00000138646	0.4791491382915877	[3,3]	[4,4]	8	hSpCas9	positive selection	2993073
88463607	88463630	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGTGCCCTACTCACACAGGTGGG	HERC5	ENSG00000138646	-0.2493415577160541	[3,3]	[2,1]	-4	hSpCas9	positive selection	3060928
88457398	88457421	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACCCTCCGGAGCAGCGCGCGG	HERC5	ENSG00000138646	0.09380999469010184	[2,2]	[1,1]	1	hSpCas9	positive selection	3060929
88463872	88463895	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTCGGTGCTGGAAAACATGGG	HERC5	ENSG00000138646	-0.3453147201634414	[3,3]	[2,0]	-5	hSpCas9	positive selection	3060930
88457316	88457339	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCGCGGCGGCCTTGCCCGCGG	HERC5	ENSG00000138646	0.19774526943573761	[3,3]	[5,0]	3	hSpCas9	positive selection	3060931
88459366	88459389		+	24336571	A375	resistance to PLX after 7 days	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.054354398798715335	[12,13]	[12,11]	-1	hSpCas9	positive selection	3118816
88459449	88459472		+	24336571	A375	resistance to PLX after 7 days	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.19621703858786277	[3,4]	[3,3]	-6	hSpCas9	positive selection	3118817
88457331	88457354		-	24336571	A375	resistance to PLX after 7 days	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.014360152030365558	[12,10]	[12,10]	0	hSpCas9	positive selection	3118818
88457455	88457478		-	24336571	A375	resistance to PLX after 7 days	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	-0.019287145617264884	[12,14]	[12,13]	0	hSpCas9	positive selection	3118819
88457453	88457476		+	24336571	A375	resistance to PLX after 7 days	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	-0.17941828887018782	[14,15]	[12,13]	-5	hSpCas9	positive selection	3118820
88459433	88459456		-	24336571	A375	resistance to PLX after 7 days	CTATAGTTGTCATACTCAAATGG	HERC5	ENSG00000138646	-0.05630844706074645	[7,6]	[7,6]	-2	hSpCas9	positive selection	3118821
88459366	88459389		+	24336571	A375	resistance to PLX after 14 days	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.007078972909218939	[12,15]	[5,6]	0	hSpCas9	positive selection	3176609
88459449	88459472		+	24336571	A375	resistance to PLX after 14 days	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.5687138961279913	[5,7]	[1,1]	-6	hSpCas9	positive selection	3176610
88457331	88457354		-	24336571	A375	resistance to PLX after 14 days	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-0.09064216386880047	[12,10]	[4,4]	-1	hSpCas9	positive selection	3176611
88457455	88457478		-	24336571	A375	resistance to PLX after 14 days	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.4345805354169178	[12,9]	[8,5]	4	hSpCas9	positive selection	3176612
88457453	88457476		+	24336571	A375	resistance to PLX after 14 days	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	0.058961689525212024	[12,16]	[9,4]	0	hSpCas9	positive selection	3176613
88459433	88459456		-	24336571	A375	resistance to PLX after 14 days	CTATAGTTGTCATACTCAAATGG	HERC5	ENSG00000138646	0.28735520832180206	[10,2]	[2,3]	3	hSpCas9	positive selection	3176614
88459366	88459389		+	24336571	A375	viability after 7 days	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.008096083778253466	[13]	[12,13]	0	hSpCas9	negative selection	3234402
88459449	88459472		+	24336571	A375	viability after 7 days	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.7790852570801923	[8]	[3,4]	-8	hSpCas9	negative selection	3234403
88457331	88457354		-	24336571	A375	viability after 7 days	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.42186909587599963	[8]	[12,10]	6	hSpCas9	negative selection	3234404
88457455	88457478		-	24336571	A375	viability after 7 days	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.49090178258548345	[9]	[12,14]	7	hSpCas9	negative selection	3234405
88457453	88457476		+	24336571	A375	viability after 7 days	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	0.7121268117489139	[9]	[14,15]	9	hSpCas9	negative selection	3234406
88459433	88459456		-	24336571	A375	viability after 7 days	CTATAGTTGTCATACTCAAATGG	HERC5	ENSG00000138646	-0.3493682293039203	[10]	[7,6]	-5	hSpCas9	negative selection	3234407
88459366	88459389		+	24336571	A375	viability after 14 days	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.1131083061672984	[13]	[12,15]	1	hSpCas9	negative selection	3292195
88459449	88459472		+	24336571	A375	viability after 14 days	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.22208800983007204	[8]	[5,7]	-3	hSpCas9	negative selection	3292196
88457331	88457354		-	24336571	A375	viability after 14 days	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.4728921333922613	[8]	[12,10]	6	hSpCas9	negative selection	3292197
88457455	88457478		-	24336571	A375	viability after 14 days	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.30317968544586754	[9]	[12,9]	4	hSpCas9	negative selection	3292198
88457453	88457476		+	24336571	A375	viability after 14 days	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	0.7107163867100996	[9]	[12,16]	8	hSpCas9	negative selection	3292199
88459433	88459456		-	24336571	A375	viability after 14 days	CTATAGTTGTCATACTCAAATGG	HERC5	ENSG00000138646	-0.4737541551656661	[10]	[10,2]	-5	hSpCas9	negative selection	3292200
88457455	88457478	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.3753225837192317	[109,125]	[0,0]	2	hSpCas9	positive selection	3353260
88457331	88457354	4	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.30815751439979117	[162,207]	[0,1]	1	hSpCas9	positive selection	3353261
88459366	88459389	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.8845972533385815	[276,287]	[0,0]	-6	hSpCas9	positive selection	3353262
88459449	88459472	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.7337642553888224	[91,91]	[0,0]	3	hSpCas9	positive selection	3372454
88460150	88460173	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	-0.43616074605349014	[206,206]	[0,0]	-3	hSpCas9	positive selection	3372455
88460120	88460143	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	-0.03729453744579207	[156,156]	[0,0]	0	hSpCas9	positive selection	3372456
88463606	88463629	4	+	26780180	HT29	viability (Avana library 4 designs)	AGTGCCCTACTCACACAGGTGGG	HERC5	ENSG00000138646	1.75157316911712	[]	[]	6	hSpCas9	negative selection	3430331
88457398	88457421	4	-	26780180	HT29	viability (Avana library 4 designs)	CCACCCTCCGGAGCAGCGCGCGG	HERC5	ENSG00000138646	0.576688611162784	[]	[]	2	hSpCas9	negative selection	3430332
88463871	88463894	4	+	26780180	HT29	viability (Avana library 4 designs)	CTTTCGGTGCTGGAAAACATGGG	HERC5	ENSG00000138646	0.0213119011527469	[]	[]	0	hSpCas9	negative selection	3430333
88457316	88457339	4	-	26780180	HT29	viability (Avana library 4 designs)	GGTCGCGGCGGCCTTGCCCGCGG	HERC5	ENSG00000138646	0.172209571636313	[]	[]	0	hSpCas9	negative selection	3430334
88457316	88457339	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCGCGGCGGCCTTGCCCGCGG	HERC5	ENSG00000138646	4.54045858658028	[]	[]	7	hSpCas9	negative selection	3515439
88457398	88457421	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACCCTCCGGAGCAGCGCGCGG	HERC5	ENSG00000138646	7.31249974419394	[]	[]	9	hSpCas9	negative selection	3515440
88463871	88463894	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTCGGTGCTGGAAAACATGGG	HERC5	ENSG00000138646	4.69770207252867	[]	[]	7	hSpCas9	negative selection	3515441
88463606	88463629	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGCCCTACTCACACAGGTGGG	HERC5	ENSG00000138646	1.54332611150171	[]	[]	2	hSpCas9	negative selection	3515442
88457395	88457418	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCACCGCGCGCTGCTCCGGAGGG	HERC5	ENSG00000138646	1.40766443025179	[]	[]	2	hSpCas9	negative selection	3515443
88457268	88457291	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	4.00665619019621	[]	[]	6	hSpCas9	negative selection	3515444
88457316	88457339	4	-	26780180	A375	viability (Avana lentiGuide)	GGTCGCGGCGGCCTTGCCCGCGG	HERC5	ENSG00000138646	3.86483703177424	[]	[]	4	hSpCas9	negative selection	3624098
88457398	88457421	4	-	26780180	A375	viability (Avana lentiGuide)	CCACCCTCCGGAGCAGCGCGCGG	HERC5	ENSG00000138646	-2.72320785282617	[]	[]	-5	hSpCas9	negative selection	3624099
88463871	88463894	4	+	26780180	A375	viability (Avana lentiGuide)	CTTTCGGTGCTGGAAAACATGGG	HERC5	ENSG00000138646	-1.58726028484802	[]	[]	-3	hSpCas9	negative selection	3624100
88463606	88463629	4	+	26780180	A375	viability (Avana lentiGuide)	AGTGCCCTACTCACACAGGTGGG	HERC5	ENSG00000138646	0.203599279338451	[]	[]	0	hSpCas9	negative selection	3624101
88457395	88457418	4	+	26780180	A375	viability (Avana lentiGuide)	CCACCGCGCGCTGCTCCGGAGGG	HERC5	ENSG00000138646	-3.58097232531004	[]	[]	-6	hSpCas9	negative selection	3624102
88457268	88457291	4	+	26780180	A375	viability (Avana lentiGuide)	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	3.08592774220769	[]	[]	3	hSpCas9	negative selection	3624103
88457316	88457339	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCGCGGCGGCCTTGCCCGCGG	HERC5	ENSG00000138646	0.24056403837291251	[4]	[5,4]	6	hSpCas9	positive selection	3732757
88457398	88457421	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACCCTCCGGAGCAGCGCGCGG	HERC5	ENSG00000138646	0.16132932441405953	[3]	[5,3]	4	hSpCas9	positive selection	3732758
88463871	88463894	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTCGGTGCTGGAAAACATGGG	HERC5	ENSG00000138646	0.3474890915161283	[4]	[5,5]	9	hSpCas9	positive selection	3732759
88463606	88463629	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGCCCTACTCACACAGGTGGG	HERC5	ENSG00000138646	0.15659078479431204	[4]	[5,4]	4	hSpCas9	positive selection	3732760
88457395	88457418	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACCGCGCGCTGCTCCGGAGGG	HERC5	ENSG00000138646	0.17119559216084387	[4]	[4,5]	4	hSpCas9	positive selection	3732761
88457268	88457291	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	0.17806329315197014	[3]	[4,3]	5	hSpCas9	positive selection	3732762
88457316	88457339	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCGCGGCGGCCTTGCCCGCGG	HERC5	ENSG00000138646	-0.2404225562952282	[6]	[4,3]	-3	hSpCas9	positive selection	3841364
88457398	88457421	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACCCTCCGGAGCAGCGCGCGG	HERC5	ENSG00000138646	-0.47860489152206487	[4]	[2,1]	-6	hSpCas9	positive selection	3841365
88463871	88463894	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTCGGTGCTGGAAAACATGGG	HERC5	ENSG00000138646	0.21430370689730682	[5]	[5,5]	5	hSpCas9	positive selection	3841366
88463606	88463629	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGCCCTACTCACACAGGTGGG	HERC5	ENSG00000138646	0.4002050526924018	[5]	[6,5]	9	hSpCas9	positive selection	3841367
88457395	88457418	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACCGCGCGCTGCTCCGGAGGG	HERC5	ENSG00000138646	-0.07755408002627144	[4]	[3,4]	-1	hSpCas9	positive selection	3841368
88457268	88457291	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGATGGAGCGGAGGTCGCGGAGG	HERC5	ENSG00000138646	0.14821324177051928	[4]	[3,4]	3	hSpCas9	positive selection	3841369
88460120	88460143	4	+	26780180	A375	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.340227103199737	[]	[]	0	hSpCas9	negative selection	3947431
88459366	88459389	4	+	26780180	A375	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.331416836976461	[]	[]	0	hSpCas9	negative selection	3947432
88459449	88459472	4	+	26780180	A375	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.928373553229268	[]	[]	4	hSpCas9	negative selection	3947433
88457331	88457354	4	-	26780180	A375	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.241384735228701	[]	[]	0	hSpCas9	negative selection	3947434
88460150	88460173	4	+	26780180	A375	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.459802751454502	[]	[]	1	hSpCas9	negative selection	3947435
88457455	88457478	4	-	26780180	A375	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	1.08785213057191	[]	[]	5	hSpCas9	negative selection	3947436
88460120	88460143	4	+	26780180	HT29	viability (GeCKOv2 library)	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.64030276837579	[]	[]	2	hSpCas9	negative selection	4055397
88459366	88459389	4	+	26780180	HT29	viability (GeCKOv2 library)	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.336259332186823	[]	[]	0	hSpCas9	negative selection	4055398
88459449	88459472	4	+	26780180	HT29	viability (GeCKOv2 library)	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.939557423726534	[]	[]	4	hSpCas9	negative selection	4055399
88457331	88457354	4	-	26780180	HT29	viability (GeCKOv2 library)	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.14100260856994	[]	[]	0	hSpCas9	negative selection	4055400
88460150	88460173	4	+	26780180	HT29	viability (GeCKOv2 library)	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.503611002454446	[]	[]	1	hSpCas9	negative selection	4055401
88457455	88457478	4	-	26780180	HT29	viability (GeCKOv2 library)	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.678028955075153	[]	[]	2	hSpCas9	negative selection	4055402
88459366	88459389	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.06002237282229858	[3]	[1,2]	-1	hSpCas9	positive selection	4142278
88459449	88459472	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.4171190436452916	[2]	[4,0]	8	hSpCas9	positive selection	4142279
88457331	88457354	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-0.18863914371558738	[3]	[1,2]	-4	hSpCas9	positive selection	4142280
88457455	88457478	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.12353714822843673	[3]	[2,2]	3	hSpCas9	positive selection	4142281
88457453	88457476	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	0.5155334970228703	[3]	[4,2]	9	hSpCas9	positive selection	4142282
88459433	88459456	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTATAGTTGTCATACTCAAATGG	HERC5	ENSG00000138646	-0.0752913328538111	[3]	[1,1]	-2	hSpCas9	positive selection	4142283
88459366	88459389	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.29920462341931153	[3]	[3,4,2,0]	2	hSpCas9	positive selection	4206300
88459449	88459472	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.6980410231907273	[0]	[0,0,0,0]	4	hSpCas9	positive selection	4206301
88457331	88457354	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	1.1109046753090135	[2]	[0,3,0,3]	8	hSpCas9	positive selection	4206302
88457455	88457478	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	-0.062129411037303364	[4]	[1,2,2,0]	-1	hSpCas9	positive selection	4206303
88457453	88457476	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCTCGCGGTCTTGGAACGCGG	HERC5	ENSG00000138646	0.9546486566715745	[3]	[1,2,0,3]	6	hSpCas9	positive selection	4206304
88459433	88459456	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTATAGTTGTCATACTCAAATGG	HERC5	ENSG00000138646	0.6402139141949931	[1]	[0,2,0,0]	4	hSpCas9	positive selection	4206305
88457455	88457478	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.3704336499731453	[2]	[2,2]	7	hSpCas9	positive selection	4274844
88457331	88457354	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.33837009971734705	[3]	[3,3]	7	hSpCas9	positive selection	4274845
88459366	88459389	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.205560687872606	[4]	[4,2]	4	hSpCas9	positive selection	4274846
88459449	88459472	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.3192553455546459	[2]	[2,2]	6	hSpCas9	positive selection	4339105
88460150	88460173	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.2297777210037788	[2]	[2,1]	4	hSpCas9	positive selection	4339106
88460120	88460143	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.022549331066717915	[2]	[3,0]	0	hSpCas9	positive selection	4339107
88457457	88457479	4	+	27760321	OCIAML3	viability	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.9568951583047215	[442,415]	[635,673]	9	hSpCas9	negative selection	4406658
88459374	88459396	4	+	27760321	OCIAML3	viability	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.01772011417137276	[581,461]	[418,399]	0	hSpCas9	negative selection	4406659
88472482	88472504	4	+	27760321	OCIAML3	viability	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-3.177492371879201	[20,21]	[0,2]	-9	hSpCas9	negative selection	4406660
88462216	88462238	4	+	27760321	OCIAML3	viability	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	0.3326598163215526	[918,952]	[769,1129]	4	hSpCas9	negative selection	4406661
88462324	88462346	4	+	27760321	OCIAML3	viability	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.4651151482870224	[564,553]	[506,733]	5	hSpCas9	negative selection	4406662
88457457	88457479	4	+	27760321	OCIAML2	viability	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.1850187966160166	[442,415]	[355,446]	2	hSpCas9	negative selection	4490121
88459374	88459396	4	+	27760321	OCIAML2	viability	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.33343106668099826	[581,461]	[432,654]	4	hSpCas9	negative selection	4490122
88472482	88472504	4	+	27760321	OCIAML2	viability	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-0.5645320950717867	[20,21]	[16,4]	-6	hSpCas9	negative selection	4490123
88462216	88462238	4	+	27760321	OCIAML2	viability	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	0.5772787431925466	[918,952]	[1009,1299]	7	hSpCas9	negative selection	4490124
88462324	88462346	4	+	27760321	OCIAML2	viability	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.7661819227999979	[564,553]	[794,740]	9	hSpCas9	negative selection	4490125
88457457	88457479	4	+	27760321	MV411	viability	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-2.1207059079353483	[442,415]	[83,36]	-8	hSpCas9	negative selection	4573584
88459374	88459396	4	+	27760321	MV411	viability	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.5138413302766318	[581,461]	[198,300]	-4	hSpCas9	negative selection	4573585
88472482	88472504	4	+	27760321	MV411	viability	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-3.8340587309859453	[20,21]	[0,0]	-9	hSpCas9	negative selection	4573586
88462216	88462238	4	+	27760321	MV411	viability	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	0.8404312797313314	[918,952]	[468,2075]	6	hSpCas9	negative selection	4573587
88462324	88462346	4	+	27760321	MV411	viability	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	1.1184106359269044	[564,553]	[777,841]	7	hSpCas9	negative selection	4573588
88457457	88457479	4	+	27760321	HL60	viability	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.01699875576145202	[442,415]	[362,329]	0	hSpCas9	negative selection	4657047
88459374	88459396	4	+	27760321	HL60	viability	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.3342347184568529	[581,461]	[360,717]	4	hSpCas9	negative selection	4657048
88472482	88472504	4	+	27760321	HL60	viability	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	0.43420358537223036	[20,21]	[18,28]	5	hSpCas9	negative selection	4657049
88462216	88462238	4	+	27760321	HL60	viability	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	0.7712166885295799	[918,952]	[1432,1181]	8	hSpCas9	negative selection	4657050
88462324	88462346	4	+	27760321	HL60	viability	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.4188157913046301	[564,553]	[711,506]	5	hSpCas9	negative selection	4657051
88457457	88457479	4	+	27760321	HT1080	viability	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	-0.1819979659724567	[415,324]	[142,115]	-1	hSpCas9	negative selection	4740510
88459374	88459396	4	+	27760321	HT1080	viability	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.7100085001865934	[461,360]	[292,240]	4	hSpCas9	negative selection	4740511
88472482	88472504	4	+	27760321	HT1080	viability	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	6.052357287257609	[21,16]	[540,486]	9	hSpCas9	negative selection	4740512
88462216	88462238	4	+	27760321	HT1080	viability	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	-5.762563001473693	[952,743]	[10,0]	-8	hSpCas9	negative selection	4740513
88462324	88462346	4	+	27760321	HT1080	viability	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	1.6111415845550208	[553,432]	[571,631]	8	hSpCas9	negative selection	4740514
88457457	88457479	4	+	27760321	HT29	viability after 7 days	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.2365075653118296	[415,324]	[562,584,535]	3	hSpCas9	negative selection	4823973
88459374	88459396	4	+	27760321	HT29	viability after 7 days	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.11582881086774023	[461,360]	[460,565,434]	-2	hSpCas9	negative selection	4823974
88472482	88472504	4	+	27760321	HT29	viability after 7 days	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-2.6382708680975995	[21,16]	[3,1,5]	-9	hSpCas9	negative selection	4823975
88462216	88462238	4	+	27760321	HT29	viability after 7 days	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	-0.2401413142128016	[952,743]	[1181,748,876]	-3	hSpCas9	negative selection	4823976
88462324	88462346	4	+	27760321	HT29	viability after 7 days	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.24493704039115227	[553,432]	[641,744,848]	4	hSpCas9	negative selection	4823977
88457457	88457479	4	+	27760321	HT29	viability after 25 days	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.8048626125141466	[415,324]	[709,683,835]	8	hSpCas9	negative selection	4907436
88459374	88459396	4	+	27760321	HT29	viability after 25 days	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.043033788438572224	[461,360]	[424,443,506]	0	hSpCas9	negative selection	4907437
88472482	88472504	4	+	27760321	HT29	viability after 25 days	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-2.031772554000291	[21,16]	[3,1,10]	-8	hSpCas9	negative selection	4907438
88462216	88462238	4	+	27760321	HT29	viability after 25 days	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	0.03094413479167346	[952,743]	[1070,960,926]	0	hSpCas9	negative selection	4907439
88462324	88462346	4	+	27760321	HT29	viability after 25 days	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.5578820175096092	[553,432]	[635,991,878]	6	hSpCas9	negative selection	4907440
88457457	88457479	4	+	27760321	HT29	viability after 22 days	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.6344952137986721	[415,324]	[845,473,669]	7	hSpCas9	negative selection	4990899
88459374	88459396	4	+	27760321	HT29	viability after 22 days	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.085139254823421	[461,360]	[566,367,577]	0	hSpCas9	negative selection	4990900
88472482	88472504	4	+	27760321	HT29	viability after 22 days	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-1.3967406075204671	[21,16]	[0,2,21]	-7	hSpCas9	negative selection	4990901
88462216	88462238	4	+	27760321	HT29	viability after 22 days	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	0.02896697719390051	[952,743]	[936,976,1090]	0	hSpCas9	negative selection	4990902
88462324	88462346	4	+	27760321	HT29	viability after 22 days	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.4481475753563541	[553,432]	[864,778,687]	5	hSpCas9	negative selection	4990903
88457457	88457479	4	+	27760321	HT29	viability after 19 days	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	1.0754439129683566	[415,324]	[1306,1170,267]	9	hSpCas9	negative selection	5074362
88459374	88459396	4	+	27760321	HT29	viability after 19 days	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.5503182745091979	[461,360]	[932,503,656]	5	hSpCas9	negative selection	5074363
88472482	88472504	4	+	27760321	HT29	viability after 19 days	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	1.0755167478259833	[21,16]	[40,98,1]	9	hSpCas9	negative selection	5074364
88462216	88462238	4	+	27760321	HT29	viability after 19 days	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	-0.1322293538675683	[952,743]	[962,819,880]	-1	hSpCas9	negative selection	5074365
88462324	88462346	4	+	27760321	HT29	viability after 19 days	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.525885184587913	[553,432]	[887,919,643]	5	hSpCas9	negative selection	5074366
88457457	88457479	4	+	27760321	HT29	viability after 16 days	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.42264352601034805	[415,324]	[703,626,347]	5	hSpCas9	negative selection	5157825
88459374	88459396	4	+	27760321	HT29	viability after 16 days	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.4605553640142093	[461,360]	[930,277,728]	5	hSpCas9	negative selection	5157826
88472482	88472504	4	+	27760321	HT29	viability after 16 days	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-0.005739874940270617	[21,16]	[29,18,16]	0	hSpCas9	negative selection	5157827
88462216	88462238	4	+	27760321	HT29	viability after 16 days	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	-0.08478843522050239	[952,743]	[892,1050,736]	-1	hSpCas9	negative selection	5157828
88462324	88462346	4	+	27760321	HT29	viability after 16 days	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.7905396378147841	[553,432]	[1113,962,802]	8	hSpCas9	negative selection	5157829
88457457	88457479	4	+	27760321	HT29	viability after 13 days	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.17801601258574146	[415,324]	[607,559,301]	2	hSpCas9	negative selection	5241288
88459374	88459396	4	+	27760321	HT29	viability after 13 days	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.20424782144118062	[461,360]	[418,373,447]	-2	hSpCas9	negative selection	5241289
88472482	88472504	4	+	27760321	HT29	viability after 13 days	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-0.9715858480394024	[21,16]	[8,3,20]	-7	hSpCas9	negative selection	5241290
88462216	88462238	4	+	27760321	HT29	viability after 13 days	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	0.017094654250555674	[952,743]	[996,941,1045]	0	hSpCas9	negative selection	5241291
88462324	88462346	4	+	27760321	HT29	viability after 13 days	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.36022246978881844	[553,432]	[989,476,736]	4	hSpCas9	negative selection	5241292
88457457	88457479	4	+	27760321	HT29	viability after 10 days	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.08921287482392824	[415,324]	[552,558,368]	1	hSpCas9	negative selection	5324751
88459374	88459396	4	+	27760321	HT29	viability after 10 days	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.06075496727294427	[461,360]	[664,238,564]	-1	hSpCas9	negative selection	5324752
88472482	88472504	4	+	27760321	HT29	viability after 10 days	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-0.12109587995072157	[21,16]	[64,0,0]	-2	hSpCas9	negative selection	5324753
88462216	88462238	4	+	27760321	HT29	viability after 10 days	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	-0.24046606975330886	[952,743]	[1161,774,752]	-3	hSpCas9	negative selection	5324754
88462324	88462346	4	+	27760321	HT29	viability after 10 days	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.3290194197749725	[553,432]	[839,682,795]	4	hSpCas9	negative selection	5324755
88457457	88457479	4	+	27760321	MOLM13	viability	TCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.45381245091441935	[442,415]	[632,75]	3	hSpCas9	negative selection	5408214
88459374	88459396	4	+	27760321	MOLM13	viability	AGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	1.3628293716675481	[581,461]	[795,715]	8	hSpCas9	negative selection	5408215
88472482	88472504	4	+	27760321	MOLM13	viability	AAGGACTGGATTACTAACATGG	HERC5	ENSG00000138646	-0.07665177666299616	[20,21]	[3,17]	0	hSpCas9	negative selection	5408216
88462216	88462238	4	+	27760321	MOLM13	viability	AGATTGTGGAGCACCTCGCAGG	HERC5	ENSG00000138646	-0.10517080599601503	[918,952]	[616,387]	0	hSpCas9	negative selection	5408217
88462324	88462346	4	+	27760321	MOLM13	viability	AATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.24724202550827468	[564,553]	[158,559]	1	hSpCas9	negative selection	5408218
88457173	88457196	4	+	27661255	K562	viability	GCTCTGCAGCGCAACGCCTGAGG	HERC5	ENSG00000138646	0.5169337347118725	[60,201]	[168,128]	9	dCas9-KRAB	negative selection	5484459
88457195	88457218	4	+	27661255	K562	viability	GCAGTGGGCGCGCTCAGTCCCGG	HERC5	ENSG00000138646	0.3236828801979328	[486,415]	[497,413]	9	dCas9-KRAB	negative selection	5484460
88457522	88457545	4	+	27661255	K562	viability	GCCCGGACGCCGAGTGAGTGGGG	HERC5	ENSG00000138646	0.11900252251452659	[380,435]	[393,318]	4	dCas9-KRAB	negative selection	5484461
88457431	88457454	4	-	27661255	K562	viability	GCCCCGGCGAGCAGCAGAGTTGG	HERC5	ENSG00000138646	0.1770962501418909	[355,390]	[400,281]	6	dCas9-KRAB	negative selection	5484462
88457455	88457478	4	-	27260156	BXPC3	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.3347823678956612	[419]	[542,491,501,695]	7	hSpCas9	negative selection	5547304
88457331	88457354	4	-	27260156	BXPC3	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.38060936573902165	[571]	[825,735,822,713]	7	hSpCas9	negative selection	5547305
88459366	88459389	4	+	27260156	BXPC3	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.07670235904171152	[1119]	[1156,1283,1138,1371]	1	hSpCas9	negative selection	5547306
88459449	88459472	4	+	27260156	BXPC3	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.26140611713125383	[264]	[329,306,336,356]	6	hSpCas9	negative selection	5611565
88460150	88460173	4	+	27260156	BXPC3	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.45153151098822614	[290]	[415,319,416,527]	8	hSpCas9	negative selection	5611566
88460120	88460143	4	+	27260156	BXPC3	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.051938790612539365	[267]	[191,307,250,435]	1	hSpCas9	negative selection	5611567
88457455	88457478	4	-	27260156	A673	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.3192008406882934	[419]	[517,606,662,719]	7	hSpCas9	negative selection	5668555
88457331	88457354	4	-	27260156	A673	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.3247467126437327	[571]	[1020,777,980,667]	7	hSpCas9	negative selection	5668556
88459366	88459389	4	+	27260156	A673	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.17728509480314725	[1119]	[1813,1415,1564,1308]	4	hSpCas9	negative selection	5668557
88459449	88459472	4	+	27260156	A673	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.288846568859886	[264]	[340,353,447,406]	6	hSpCas9	negative selection	5732816
88460150	88460173	4	+	27260156	A673	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.4085941531394791	[290]	[529,440,425,465]	8	hSpCas9	negative selection	5732817
88460120	88460143	4	+	27260156	A673	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.009792164768631095	[267]	[326,316,353,295]	0	hSpCas9	negative selection	5732818
88457455	88457478	4	-	27260156	A375	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.16797458943009222	[419]	[519,556,408,698]	2	hSpCas9	negative selection	5789806
88457331	88457354	4	-	27260156	A375	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.4325874415930036	[571]	[819,953,814,1007]	6	hSpCas9	negative selection	5789807
88459366	88459389	4	+	27260156	A375	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.006767232469059747	[1119]	[1099,1344,1621,1157]	0	hSpCas9	negative selection	5789808
88459449	88459472	4	+	27260156	A375	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.31937747332485744	[264]	[300,322,588,327]	5	hSpCas9	negative selection	5854067
88460150	88460173	4	+	27260156	A375	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.9374931134459016	[290]	[446,1004,730,485]	9	hSpCas9	negative selection	5854068
88460120	88460143	4	+	27260156	A375	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.6669919437813568	[267]	[597,854,302,303]	8	hSpCas9	negative selection	5854069
88457455	88457478	4	-	27260156	COLO741	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.3044855806037565	[419]	[681,694,614]	6	hSpCas9	negative selection	5911057
88457331	88457354	4	-	27260156	COLO741	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.32673577683974026	[571]	[1059,829,872]	6	hSpCas9	negative selection	5911058
88459366	88459389	4	+	27260156	COLO741	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.11257014066833104	[1119]	[1646,1517,1485]	2	hSpCas9	negative selection	5911059
88459449	88459472	4	+	27260156	COLO741	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.12611598053618867	[264]	[439,323,350]	2	hSpCas9	negative selection	5975318
88460150	88460173	4	+	27260156	COLO741	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	-0.05422828104470123	[290]	[401,398,281]	-1	hSpCas9	negative selection	5975319
88460120	88460143	4	+	27260156	COLO741	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.08200231024936577	[267]	[297,375,403]	1	hSpCas9	negative selection	5975320
88457455	88457478	4	-	27260156	CAL120	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	-0.12880245923156128	[419]	[557,585,304]	-2	hSpCas9	negative selection	6032308
88457331	88457354	4	-	27260156	CAL120	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.5094225224934297	[571]	[1148,1083,829]	7	hSpCas9	negative selection	6032309
88459366	88459389	4	+	27260156	CAL120	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.2596219198924048	[1119]	[1923,1491,1627]	4	hSpCas9	negative selection	6032310
88459449	88459472	4	+	27260156	CAL120	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.03300001902150185	[264]	[191,422,331]	0	hSpCas9	negative selection	6096569
88460150	88460173	4	+	27260156	CAL120	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.540225141320741	[290]	[336,685,527]	7	hSpCas9	negative selection	6096570
88460120	88460143	4	+	27260156	CAL120	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	-0.006403474185378011	[267]	[283,277,424]	0	hSpCas9	negative selection	6096571
88457455	88457478	4	-	27260156	CADOES1	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.18103001974571192	[419]	[581,459,339,386]	3	hSpCas9	negative selection	6153559
88457331	88457354	4	-	27260156	CADOES1	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.6249581646913209	[571]	[876,771,695,940]	8	hSpCas9	negative selection	6153560
88459366	88459389	4	+	27260156	CADOES1	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.08828516856134483	[1119]	[964,1209,1151,1102]	1	hSpCas9	negative selection	6153561
88459449	88459472	4	+	27260156	CADOES1	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.0033956488293341858	[264]	[185,241,275,280]	0	hSpCas9	negative selection	6217820
88460150	88460173	4	+	27260156	CADOES1	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.49287121820310964	[290]	[335,334,355,500]	7	hSpCas9	negative selection	6217821
88460120	88460143	4	+	27260156	CADOES1	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.7323741342835816	[267]	[535,285,262,576]	9	hSpCas9	negative selection	6217822
88457455	88457478	4	-	27260156	EWS502	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.3190280881279647	[419]	[355,416,531,971]	5	hSpCas9	negative selection	6274810
88457331	88457354	4	-	27260156	EWS502	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.23737077114893995	[571]	[683,662,718,799]	4	hSpCas9	negative selection	6274811
88459366	88459389	4	+	27260156	EWS502	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.07388419805856627	[1119]	[1177,1143,1241,1452]	1	hSpCas9	negative selection	6274812
88459449	88459472	4	+	27260156	EWS502	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.11574055824397733	[264]	[299,235,373,309]	2	hSpCas9	negative selection	6339071
88460150	88460173	4	+	27260156	EWS502	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.542338988780315	[290]	[342,533,485,439]	8	hSpCas9	negative selection	6339072
88460120	88460143	4	+	27260156	EWS502	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.31577984111682467	[267]	[373,298,273,471]	5	hSpCas9	negative selection	6339073
88457455	88457478	4	-	27260156	EW8	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.017572241390988896	[419]	[332,370,338,333]	0	hSpCas9	negative selection	6396061
88457331	88457354	4	-	27260156	EW8	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.45879197636935326	[571]	[791,669,512,609]	7	hSpCas9	negative selection	6396062
88459366	88459389	4	+	27260156	EW8	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.08691417953904135	[1119]	[1079,775,798,794]	-2	hSpCas9	negative selection	6396063
88459449	88459472	4	+	27260156	EW8	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.15950005713930593	[264]	[194,180,172,222]	-3	hSpCas9	negative selection	6460322
88460150	88460173	4	+	27260156	EW8	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.6371921330980151	[290]	[388,424,312,350]	9	hSpCas9	negative selection	6460323
88460120	88460143	4	+	27260156	EW8	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.4552689050523233	[267]	[271,259,339,307]	7	hSpCas9	negative selection	6460324
88457455	88457478	4	-	27260156	CORL105	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.4403043937991661	[419]	[604,599,947,558]	7	hSpCas9	negative selection	6517312
88457331	88457354	4	-	27260156	CORL105	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.5203644812804802	[571]	[812,967,1230,866]	8	hSpCas9	negative selection	6517313
88459366	88459389	4	+	27260156	CORL105	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.017532292373228398	[1119]	[1312,1192,1571,1270]	0	hSpCas9	negative selection	6517314
88459449	88459472	4	+	27260156	CORL105	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.271979179637757	[264]	[316,379,374,423]	5	hSpCas9	negative selection	6581573
88460150	88460173	4	+	27260156	CORL105	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.5745453794504313	[290]	[609,461,389,552]	9	hSpCas9	negative selection	6581574
88460120	88460143	4	+	27260156	CORL105	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.2539931024738632	[267]	[280,351,597,297]	5	hSpCas9	negative selection	6581575
88457455	88457478	4	-	27260156	HS294T	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.05423009254397057	[419]	[95,275,137,166]	0	hSpCas9	negative selection	6638563
88457331	88457354	4	-	27260156	HS294T	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.25940793612211094	[571]	[254,279,215,315]	3	hSpCas9	negative selection	6638564
88459366	88459389	4	+	27260156	HS294T	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.44726449056075845	[1119]	[346,285,249,397]	-6	hSpCas9	negative selection	6638565
88459449	88459472	4	+	27260156	HS294T	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.04561410248650888	[264]	[114,60,103,119]	0	hSpCas9	negative selection	6702824
88460150	88460173	4	+	27260156	HS294T	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.24176458882695284	[290]	[116,145,105,169]	3	hSpCas9	negative selection	6702825
88460120	88460143	4	+	27260156	HS294T	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	-0.03103431137058843	[267]	[82,131,84,106]	0	hSpCas9	negative selection	6702826
88457455	88457478	4	-	27260156	HCC44	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.009141020843487419	[419]	[441,444,550,483]	0	hSpCas9	negative selection	6759814
88457331	88457354	4	-	27260156	HCC44	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.5399256858592789	[571]	[953,891,1218,751]	8	hSpCas9	negative selection	6759815
88459366	88459389	4	+	27260156	HCC44	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.027788165805708864	[1119]	[1325,909,1505,1315]	0	hSpCas9	negative selection	6759816
88459449	88459472	4	+	27260156	HCC44	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.3278332494050251	[264]	[493,325,384,317]	5	hSpCas9	negative selection	6824075
88460150	88460173	4	+	27260156	HCC44	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.2943213271090297	[290]	[463,338,371,443]	5	hSpCas9	negative selection	6824076
88460120	88460143	4	+	27260156	HCC44	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.18078840539154506	[267]	[502,163,454,309]	3	hSpCas9	negative selection	6824077
88457455	88457478	4	-	27260156	G402	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.15411376205704722	[419]	[680,557,524,531]	2	hSpCas9	negative selection	6881065
88457331	88457354	4	-	27260156	G402	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.7510990265912212	[571]	[1494,855,729,1618]	8	hSpCas9	negative selection	6881066
88459366	88459389	4	+	27260156	G402	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.2760702061351956	[1119]	[1303,1199,1149,896]	-3	hSpCas9	negative selection	6881067
88459449	88459472	4	+	27260156	G402	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.10509910386998378	[264]	[470,294,215,418]	1	hSpCas9	negative selection	6945326
88460150	88460173	4	+	27260156	G402	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	1.1960082886084875	[290]	[514,639,854,1169]	9	hSpCas9	negative selection	6945327
88460120	88460143	4	+	27260156	G402	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.8896196097786212	[267]	[779,778,327,570]	9	hSpCas9	negative selection	6945328
88457455	88457478	4	-	27260156	L33	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.19034572537318017	[419]	[401,205,331,485]	4	hSpCas9	negative selection	7002316
88457331	88457354	4	-	27260156	L33	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.1410146931933638	[571]	[505,296,435,601]	3	hSpCas9	negative selection	7002317
88459366	88459389	4	+	27260156	L33	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.30666397328820527	[1119]	[1023,369,552,812]	-6	hSpCas9	negative selection	7002318
88459449	88459472	4	+	27260156	L33	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.05206935083636577	[264]	[284,108,222,193]	1	hSpCas9	negative selection	7066577
88460150	88460173	4	+	27260156	L33	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.5040092234617841	[290]	[404,124,238,558]	8	hSpCas9	negative selection	7066578
88460120	88460143	4	+	27260156	L33	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.3944243484873016	[267]	[345,137,279,281]	7	hSpCas9	negative selection	7066579
88457455	88457478	4	-	27260156	K562	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.44231767954876755	[419]	[689,709,384,289]	5	hSpCas9	negative selection	7123567
88457331	88457354	4	-	27260156	K562	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.44387266100228023	[571]	[538,636,775,780]	5	hSpCas9	negative selection	7123568
88459366	88459389	4	+	27260156	K562	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.0508525087300955	[1119]	[1136,915,1039,774]	0	hSpCas9	negative selection	7123569
88459449	88459472	4	+	27260156	K562	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	1.1876157991914993	[264]	[632,753,625,187]	9	hSpCas9	negative selection	7187828
88460150	88460173	4	+	27260156	K562	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.6002321815671748	[290]	[550,331,212,468]	7	hSpCas9	negative selection	7187829
88460120	88460143	4	+	27260156	K562	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	-0.053237456962594076	[267]	[90,154,305,335]	0	hSpCas9	negative selection	7187830
88457455	88457478	4	-	27260156	HT29	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.4385495940247742	[419]	[1099,641,465,593]	8	hSpCas9	negative selection	7244818
88457331	88457354	4	-	27260156	HT29	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.4750934170828603	[571]	[896,996,1091,880]	8	hSpCas9	negative selection	7244819
88459366	88459389	4	+	27260156	HT29	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.07681121375808742	[1119]	[1666,1318,1408,1355]	1	hSpCas9	negative selection	7244820
88459449	88459472	4	+	27260156	HT29	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.2563533025080925	[264]	[353,514,397,289]	5	hSpCas9	negative selection	7309079
88460150	88460173	4	+	27260156	HT29	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.9312557295572472	[290]	[836,680,680,525]	9	hSpCas9	negative selection	7309080
88460120	88460143	4	+	27260156	HT29	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.3640727258073317	[267]	[608,336,453,296]	7	hSpCas9	negative selection	7309081
88457455	88457478	4	-	27260156	MHHES1	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.6672169415142859	[419]	[1337,739,565,476]	9	hSpCas9	negative selection	7366069
88457331	88457354	4	-	27260156	MHHES1	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.35568545212986974	[571]	[1229,901,673,584]	6	hSpCas9	negative selection	7366070
88459366	88459389	4	+	27260156	MHHES1	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.22868796304644867	[1119]	[1459,890,1298,739]	-4	hSpCas9	negative selection	7366071
88459449	88459472	4	+	27260156	MHHES1	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.25029083971030486	[264]	[524,355,385,201]	4	hSpCas9	negative selection	7430330
88460150	88460173	4	+	27260156	MHHES1	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.896825065538475	[290]	[578,731,489,628]	9	hSpCas9	negative selection	7430331
88460120	88460143	4	+	27260156	MHHES1	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.7737058546459044	[267]	[595,404,661,412]	9	hSpCas9	negative selection	7430332
88457455	88457478	4	-	27260156	MEWO	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.1821315084982825	[419]	[440,526,367]	4	hSpCas9	negative selection	7487320
88457331	88457354	4	-	27260156	MEWO	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.22807389293173558	[571]	[754,438,711]	5	hSpCas9	negative selection	7487321
88459366	88459389	4	+	27260156	MEWO	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.15034583817342928	[1119]	[1309,1160,1045]	3	hSpCas9	negative selection	7487322
88459449	88459472	4	+	27260156	MEWO	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.3793690271357135	[264]	[371,321,282]	7	hSpCas9	negative selection	7551581
88460150	88460173	4	+	27260156	MEWO	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.3782006568062885	[290]	[369,269,424]	7	hSpCas9	negative selection	7551582
88460120	88460143	4	+	27260156	MEWO	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.14739395373265174	[267]	[298,311,225]	3	hSpCas9	negative selection	7551583
88457455	88457478	4	-	27260156	LNCAPCLONEFGC	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.300295553438281	[419]	[443,544,440,434]	5	hSpCas9	negative selection	7608571
88457331	88457354	4	-	27260156	LNCAPCLONEFGC	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.3162557773758255	[571]	[564,589,844,614]	5	hSpCas9	negative selection	7608572
88459366	88459389	4	+	27260156	LNCAPCLONEFGC	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.1504355370283752	[1119]	[1087,1168,1291,976]	2	hSpCas9	negative selection	7608573
88459449	88459472	4	+	27260156	LNCAPCLONEFGC	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.37226605386971406	[264]	[234,281,451,297]	6	hSpCas9	negative selection	7672832
88460150	88460173	4	+	27260156	LNCAPCLONEFGC	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.4265418053717902	[290]	[450,299,302,356]	6	hSpCas9	negative selection	7672833
88460120	88460143	4	+	27260156	LNCAPCLONEFGC	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.27633077482359303	[267]	[197,462,242,254]	4	hSpCas9	negative selection	7672834
88457455	88457478	4	-	27260156	PANC0327	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.3251380561642232	[419]	[659,367,412,456]	5	hSpCas9	negative selection	7729822
88457331	88457354	4	-	27260156	PANC0327	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.2968522153525725	[571]	[332,606,730,803]	4	hSpCas9	negative selection	7729823
88459366	88459389	4	+	27260156	PANC0327	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.1251634061882021	[1119]	[828,669,974,1198]	-2	hSpCas9	negative selection	7729824
88459449	88459472	4	+	27260156	PANC0327	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.23223135022013008	[264]	[268,300,186,344]	3	hSpCas9	negative selection	7794083
88460150	88460173	4	+	27260156	PANC0327	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.3066368499706465	[290]	[333,248,310,394]	4	hSpCas9	negative selection	7794084
88460120	88460143	4	+	27260156	PANC0327	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.7600918658996676	[267]	[458,211,494,475]	9	hSpCas9	negative selection	7794085
88457455	88457478	4	-	27260156	NCIH2009	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.4801517344599765	[419]	[878,881,703]	6	hSpCas9	negative selection	7851073
88457331	88457354	4	-	27260156	NCIH2009	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.15874527558692902	[571]	[1022,877,799]	2	hSpCas9	negative selection	7851074
88459366	88459389	4	+	27260156	NCIH2009	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.0049456997272767644	[1119]	[1741,1231,1773]	0	hSpCas9	negative selection	7851075
88459449	88459472	4	+	27260156	NCIH2009	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.02611885602157593	[264]	[441,334,366]	0	hSpCas9	negative selection	7915334
88460150	88460173	4	+	27260156	NCIH2009	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.647785392019729	[290]	[743,585,601]	8	hSpCas9	negative selection	7915335
88460120	88460143	4	+	27260156	NCIH2009	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.6230833142240928	[267]	[1077,311,442]	8	hSpCas9	negative selection	7915336
88457455	88457478	4	-	27260156	NCIH1373	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.38593771184722747	[419]	[628,682,507,166]	4	hSpCas9	negative selection	7972324
88457331	88457354	4	-	27260156	NCIH1373	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.42985489904690083	[571]	[1114,769,584,274]	4	hSpCas9	negative selection	7972325
88459366	88459389	4	+	27260156	NCIH1373	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.9683559548896964	[1119]	[545,529,745,194]	-7	hSpCas9	negative selection	7972326
88459449	88459472	4	+	27260156	NCIH1373	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.3183150489213423	[264]	[428,233,127,49]	-3	hSpCas9	negative selection	8036585
88460150	88460173	4	+	27260156	NCIH1373	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.7789577387537551	[290]	[401,540,717,143]	7	hSpCas9	negative selection	8036586
88460120	88460143	4	+	27260156	NCIH1373	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.2918299767457532	[267]	[538,439,287,55]	3	hSpCas9	negative selection	8036587
88457455	88457478	4	-	27260156	PATU8902	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.4544128554762372	[419]	[1213,421,556,1098]	5	hSpCas9	negative selection	8093575
88457331	88457354	4	-	27260156	PATU8902	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.7096640584896794	[571]	[1214,1342,1052,1703]	7	hSpCas9	negative selection	8093576
88459366	88459389	4	+	27260156	PATU8902	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.157710890368155	[1119]	[1837,2334,1353,1489]	1	hSpCas9	negative selection	8093577
88459449	88459472	4	+	27260156	PATU8902	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.13900991645408	[264]	[213,161,726,441]	1	hSpCas9	negative selection	8157836
88460150	88460173	4	+	27260156	PATU8902	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.5656391180937518	[290]	[551,873,364,674]	6	hSpCas9	negative selection	8157837
88460120	88460143	4	+	27260156	PATU8902	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.8631803146200505	[267]	[959,561,684,472]	8	hSpCas9	negative selection	8157838
88457455	88457478	4	-	27260156	PANC1	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.2613743513516831	[419]	[387,526,636,226]	4	hSpCas9	negative selection	8214826
88457331	88457354	4	-	27260156	PANC1	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.5453209607878344	[571]	[675,779,534,853]	8	hSpCas9	negative selection	8214827
88459366	88459389	4	+	27260156	PANC1	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.08843283511639721	[1119]	[836,1173,1131,974]	1	hSpCas9	negative selection	8214828
88459449	88459472	4	+	27260156	PANC1	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.2607032710672539	[264]	[231,326,271,267]	4	hSpCas9	negative selection	8279087
88460150	88460173	4	+	27260156	PANC1	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.5822161485846545	[290]	[413,473,272,351]	8	hSpCas9	negative selection	8279088
88460120	88460143	4	+	27260156	PANC1	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.5451483044555425	[267]	[366,444,325,237]	8	hSpCas9	negative selection	8279089
88457455	88457478	4	-	27260156	PANC0813	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.5645552297817611	[419]	[758,934,790,450]	8	hSpCas9	negative selection	8336077
88457331	88457354	4	-	27260156	PANC0813	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	-0.10750623503237611	[571]	[666,534,691,604]	-2	hSpCas9	negative selection	8336078
88459366	88459389	4	+	27260156	PANC0813	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.3621126545155132	[1119]	[1150,1010,1143,810]	-5	hSpCas9	negative selection	8336079
88459449	88459472	4	+	27260156	PANC0813	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.11548245431550774	[264]	[359,239,327,230]	-2	hSpCas9	negative selection	8400338
88460150	88460173	4	+	27260156	PANC0813	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.5497628206338026	[290]	[638,465,526,387]	8	hSpCas9	negative selection	8400339
88460120	88460143	4	+	27260156	PANC0813	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.013533812238131326	[267]	[273,357,359,276]	0	hSpCas9	negative selection	8400340
88457455	88457478	4	-	27260156	RDES	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.17065103882099197	[419]	[512,425,499,768]	2	hSpCas9	negative selection	8457328
88457331	88457354	4	-	27260156	RDES	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.5115379001793503	[571]	[834,955,880,1089]	7	hSpCas9	negative selection	8457329
88459366	88459389	4	+	27260156	RDES	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.13347145543464856	[1119]	[1127,1098,1169,1295]	-2	hSpCas9	negative selection	8457330
88459449	88459472	4	+	27260156	RDES	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	-0.09561632565292355	[264]	[185,331,290,350]	-1	hSpCas9	negative selection	8521589
88460150	88460173	4	+	27260156	RDES	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.9236339045498978	[290]	[553,526,810,666]	9	hSpCas9	negative selection	8521590
88460120	88460143	4	+	27260156	RDES	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.3578219471744383	[267]	[384,353,354,491]	6	hSpCas9	negative selection	8521591
88457455	88457478	4	-	27260156	PC3	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.18491047322984316	[419]	[358,435,841,404]	4	hSpCas9	negative selection	8578579
88457331	88457354	4	-	27260156	PC3	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.6057751739950845	[571]	[709,570,1596,856]	9	hSpCas9	negative selection	8578580
88459366	88459389	4	+	27260156	PC3	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.08395044058787593	[1119]	[660,1200,2151,1221]	2	hSpCas9	negative selection	8578581
88459449	88459472	4	+	27260156	PC3	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.5727152643197999	[264]	[200,564,660,284]	9	hSpCas9	negative selection	8642840
88460150	88460173	4	+	27260156	PC3	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.700705297584206	[290]	[440,321,707,462]	9	hSpCas9	negative selection	8642841
88460120	88460143	4	+	27260156	PC3	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.227356233002177	[267]	[122,192,783,409]	5	hSpCas9	negative selection	8642842
88457455	88457478	4	-	27260156	PATU8988T	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	-0.1082642696586967	[419]	[439,516,292,260]	-2	hSpCas9	negative selection	8699830
88457331	88457354	4	-	27260156	PATU8988T	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.2408007190762072	[571]	[687,772,389,786]	4	hSpCas9	negative selection	8699831
88459366	88459389	4	+	27260156	PATU8988T	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.07263595226469466	[1119]	[1388,1007,918,1234]	1	hSpCas9	negative selection	8699832
88459449	88459472	4	+	27260156	PATU8988T	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.6221575727053292	[264]	[430,456,170,537]	8	hSpCas9	negative selection	8764091
88460150	88460173	4	+	27260156	PATU8988T	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.34525478898177736	[290]	[319,375,379,353]	6	hSpCas9	negative selection	8764092
88460120	88460143	4	+	27260156	PATU8988T	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.4396476128933795	[267]	[506,226,306,352]	7	hSpCas9	negative selection	8764093
88457455	88457478	4	-	27260156	T47D	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.15485656470682863	[419]	[576,563,553,479]	3	hSpCas9	negative selection	8821081
88457331	88457354	4	-	27260156	T47D	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.328037428395823	[571]	[807,742,775,1033]	7	hSpCas9	negative selection	8821082
88459366	88459389	4	+	27260156	T47D	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.01764007642055243	[1119]	[1468,1276,1300,1237]	0	hSpCas9	negative selection	8821083
88459449	88459472	4	+	27260156	T47D	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.3209787894137136	[264]	[330,387,440,380]	6	hSpCas9	negative selection	8885342
88460150	88460173	4	+	27260156	T47D	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.5148901824144322	[290]	[501,448,510,477]	9	hSpCas9	negative selection	8885343
88460120	88460143	4	+	27260156	T47D	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.3394561698333742	[267]	[396,375,380,428]	7	hSpCas9	negative selection	8885344
88457455	88457478	4	-	27260156	SU8686	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.31227348629913654	[419]	[516,417,548,608]	5	hSpCas9	negative selection	8942332
88457331	88457354	4	-	27260156	SU8686	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.0851601906117645	[571]	[488,673,531,728]	1	hSpCas9	negative selection	8942333
88459366	88459389	4	+	27260156	SU8686	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.10100554858190658	[1119]	[1130,743,1148,1159]	-2	hSpCas9	negative selection	8942334
88459449	88459472	4	+	27260156	SU8686	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.055782055038036016	[264]	[214,256,171,486]	0	hSpCas9	negative selection	9006593
88460150	88460173	4	+	27260156	SU8686	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.4733640239450223	[290]	[436,378,375,405]	7	hSpCas9	negative selection	9006594
88460120	88460143	4	+	27260156	SU8686	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.38828589575232436	[267]	[271,340,349,451]	6	hSpCas9	negative selection	9006595
88457455	88457478	4	-	27260156	SKES1	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.2541600728544218	[419]	[572,523,424,486]	5	hSpCas9	negative selection	9063583
88457331	88457354	4	-	27260156	SKES1	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.3573917351167309	[571]	[748,859,668,664]	7	hSpCas9	negative selection	9063584
88459366	88459389	4	+	27260156	SKES1	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.17960073933955134	[1119]	[1313,1309,1189,1248]	4	hSpCas9	negative selection	9063585
88459449	88459472	4	+	27260156	SKES1	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.25195323142615356	[264]	[499,342,291,167]	5	hSpCas9	negative selection	9127844
88460150	88460173	4	+	27260156	SKES1	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.6277441713926235	[290]	[614,400,383,411]	9	hSpCas9	negative selection	9127845
88460120	88460143	4	+	27260156	SKES1	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.10679738247783299	[267]	[322,331,272,236]	2	hSpCas9	negative selection	9127846
88457455	88457478	4	-	27260156	TOV112D	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.07364880472837881	[419]	[587,524,373,318]	1	hSpCas9	negative selection	9184834
88457331	88457354	4	-	27260156	TOV112D	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.49632481718633986	[571]	[963,831,712,742]	8	hSpCas9	negative selection	9184835
88459366	88459389	4	+	27260156	TOV112D	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.35982003039389476	[1119]	[1549,1549,1322,1370]	6	hSpCas9	negative selection	9184836
88459449	88459472	4	+	27260156	TOV112D	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.22052754923711615	[264]	[171,592,265,264]	4	hSpCas9	negative selection	9249095
88460150	88460173	4	+	27260156	TOV112D	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.4796275605478131	[290]	[422,380,443,372]	8	hSpCas9	negative selection	9249096
88460120	88460143	4	+	27260156	TOV112D	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.20513948095886425	[267]	[355,392,286,227]	4	hSpCas9	negative selection	9249097
88457455	88457478	4	-	27260156	TC71	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.282709610526543	[419]	[564,590,430,610]	7	hSpCas9	negative selection	9306085
88457331	88457354	4	-	27260156	TC71	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.14258761870354658	[571]	[626,753,673,651]	3	hSpCas9	negative selection	9306086
88459366	88459389	4	+	27260156	TC71	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	0.05782020883950789	[1119]	[1180,1299,1332,1178]	1	hSpCas9	negative selection	9306087
88459449	88459472	4	+	27260156	TC71	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.3369318193247846	[264]	[345,385,313,392]	7	hSpCas9	negative selection	9370346
88460150	88460173	4	+	27260156	TC71	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.3617542014935916	[290]	[514,280,439,360]	8	hSpCas9	negative selection	9370347
88460120	88460143	4	+	27260156	TC71	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.1647773142286607	[267]	[264,344,358,318]	4	hSpCas9	negative selection	9370348
88457455	88457478	4	-	27260156	TC32	viability	CGCCGCGTTCCAAGACCGCGAGG	HERC5	ENSG00000138646	0.14927584346961767	[419]	[350,314,519,621]	2	hSpCas9	negative selection	9427336
88457331	88457354	4	-	27260156	TC32	viability	AGACTTCGCGGGCTGGGTCGCGG	HERC5	ENSG00000138646	0.38813408278961997	[571]	[698,391,1089,783]	6	hSpCas9	negative selection	9427337
88459366	88459389	4	+	27260156	TC32	viability	AAACATGAAGATACATTCCGTGG	HERC5	ENSG00000138646	-0.11898241035682178	[1119]	[888,463,1408,1363]	-2	hSpCas9	negative selection	9427338
88459449	88459472	4	+	27260156	TC32	viability	ACTATAGCATGAAACATCTAAGG	HERC5	ENSG00000138646	0.15329192961476812	[264]	[246,198,313,376]	3	hSpCas9	negative selection	9491597
88460150	88460173	4	+	27260156	TC32	viability	CATTCTCTTGCACTCTCAAAAGG	HERC5	ENSG00000138646	0.3946294045748991	[290]	[377,186,481,460]	7	hSpCas9	negative selection	9491598
88460120	88460143	4	+	27260156	TC32	viability	AAAATAATTCAGATCACATGTGG	HERC5	ENSG00000138646	0.146700041609078	[267]	[236,212,356,338]	2	hSpCas9	negative selection	9491599
88457456	88457479	4	+	27869803	HPAFII	viability after 27 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.3300263762215412	[203]	[214,67,NaN]	2	hSpCas9	negative selection	9589278
88459373	88459396	4	+	27869803	HPAFII	viability after 27 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.20092663294117896	[206]	[141,110,NaN]	1	hSpCas9	negative selection	9589279
88462322	88462345	4	+	27869803	HPAFII	viability after 27 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.17327009949396055	[354]	[162,249,NaN]	1	hSpCas9	negative selection	9589280
88463602	88463625	4	+	27869803	HPAFII	viability after 27 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.7578313463073657	[465]	[326,486,NaN]	6	hSpCas9	negative selection	9589281
88467152	88467175	4	-	27869803	HPAFII	viability after 27 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	1.513724039928186	[184]	[232,314,NaN]	9	hSpCas9	negative selection	9589282
88469224	88469247	4	+	27869803	HPAFII	viability after 27 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.6464860769969185	[569]	[629,334,NaN]	5	hSpCas9	negative selection	9589283
88457456	88457479	4	+	27869803	HPAFII	viability after 15 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.24799610272402944	[203]	[424,157,NaN]	3	hSpCas9	negative selection	9671727
88459373	88459396	4	+	27869803	HPAFII	viability after 15 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.0077605573573064635	[206]	[314,162,NaN]	0	hSpCas9	negative selection	9671728
88462322	88462345	4	+	27869803	HPAFII	viability after 15 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	-0.07394591858105337	[354]	[359,363,NaN]	-1	hSpCas9	negative selection	9671729
88463602	88463625	4	+	27869803	HPAFII	viability after 15 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.5346467820397506	[465]	[595,805,NaN]	6	hSpCas9	negative selection	9671730
88467152	88467175	4	-	27869803	HPAFII	viability after 15 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.3664254162257165	[184]	[251,258,NaN]	4	hSpCas9	negative selection	9671731
88469224	88469247	4	+	27869803	HPAFII	viability after 15 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.2597808350677371	[569]	[1005,563,NaN]	3	hSpCas9	negative selection	9671732
88457456	88457479	4	+	27869803	ASPC1	viability after 36 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.4247933256297805	[485]	[311,290,115]	4	hSpCas9	negative selection	9754176
88459373	88459396	4	+	27869803	ASPC1	viability after 36 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	1.0615364609730071	[609]	[268,481,532]	8	hSpCas9	negative selection	9754177
88462322	88462345	4	+	27869803	ASPC1	viability after 36 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.5857822987794915	[618]	[498,68,400]	6	hSpCas9	negative selection	9754178
88463602	88463625	4	+	27869803	ASPC1	viability after 36 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.7318466416901344	[1506]	[1120,928,646]	7	hSpCas9	negative selection	9754179
88467152	88467175	4	-	27869803	ASPC1	viability after 36 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	0.7807392888219401	[452]	[359,176,281]	7	hSpCas9	negative selection	9754180
88469224	88469247	4	+	27869803	ASPC1	viability after 36 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.8479934097769235	[1447]	[227,1552,867]	7	hSpCas9	negative selection	9754181
88457456	88457479	4	+	27869803	PATU8988S	viability after 35 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.32864673856094917	[489]	[175,319,NaN]	4	hSpCas9	negative selection	9836625
88459373	88459396	4	+	27869803	PATU8988S	viability after 35 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.3093941858711162	[471]	[111,194,NaN]	-3	hSpCas9	negative selection	9836626
88462322	88462345	4	+	27869803	PATU8988S	viability after 35 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	1.2033672429825393	[637]	[681,500,NaN]	9	hSpCas9	negative selection	9836627
88463602	88463625	4	+	27869803	PATU8988S	viability after 35 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.7396404028647698	[1462]	[299,405,NaN]	-6	hSpCas9	negative selection	9836628
88467152	88467175	4	-	27869803	PATU8988S	viability after 35 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-1.3416501359294173	[471]	[77,71,NaN]	-8	hSpCas9	negative selection	9836629
88469224	88469247	4	+	27869803	PATU8988S	viability after 35 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.5391865471572602	[1070]	[762,489,NaN]	6	hSpCas9	negative selection	9836630
88457456	88457479	4	+	27869803	PATU8988S	viability after 31 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.35688228897818103	[489]	[152,373,NaN]	4	hSpCas9	negative selection	9919074
88459373	88459396	4	+	27869803	PATU8988S	viability after 31 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	-0.1825955068055288	[471]	[127,213,NaN]	-2	hSpCas9	negative selection	9919075
88462322	88462345	4	+	27869803	PATU8988S	viability after 31 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	1.0552320038724925	[637]	[591,447,NaN]	9	hSpCas9	negative selection	9919076
88463602	88463625	4	+	27869803	PATU8988S	viability after 31 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	-0.495961505529391	[1462]	[293,565,NaN]	-5	hSpCas9	negative selection	9919077
88467152	88467175	4	-	27869803	PATU8988S	viability after 31 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	-0.4850662191486297	[471]	[71,213,NaN]	-5	hSpCas9	negative selection	9919078
88469224	88469247	4	+	27869803	PATU8988S	viability after 31 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.5507918450357251	[1070]	[757,456,NaN]	6	hSpCas9	negative selection	9919079
88457456	88457479	4	+	27869803	HPAFII	viability after 35 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.409026615743199	[203]	[154,116,NaN]	2	hSpCas9	negative selection	10001523
88459373	88459396	4	+	27869803	HPAFII	viability after 35 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.531643835451659	[206]	[182,115,NaN]	3	hSpCas9	negative selection	10001524
88462322	88462345	4	+	27869803	HPAFII	viability after 35 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.3797785820165591	[354]	[143,334,NaN]	2	hSpCas9	negative selection	10001525
88463602	88463625	4	+	27869803	HPAFII	viability after 35 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.8765338168414266	[465]	[204,689,NaN]	6	hSpCas9	negative selection	10001526
88467152	88467175	4	-	27869803	HPAFII	viability after 35 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	2.0232762675015543	[184]	[280,492,NaN]	9	hSpCas9	negative selection	10001527
88469224	88469247	4	+	27869803	HPAFII	viability after 35 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.8913581680506153	[569]	[697,351,NaN]	6	hSpCas9	negative selection	10001528
88457456	88457479	4	+	27869803	HPAFII	viability after 31 days	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.15246770377945754	[203]	[143,108,NaN]	1	hSpCas9	negative selection	10083972
88459373	88459396	4	+	27869803	HPAFII	viability after 31 days	AAGATACATTCCGTGGACCAAGG	HERC5	ENSG00000138646	0.016050338777897244	[206]	[127,105,NaN]	0	hSpCas9	negative selection	10083973
88462322	88462345	4	+	27869803	HPAFII	viability after 31 days	TGAATGTGGACAACTAGGCCTGG	HERC5	ENSG00000138646	0.3375030193842543	[354]	[111,403,NaN]	2	hSpCas9	negative selection	10083974
88463602	88463625	4	+	27869803	HPAFII	viability after 31 days	TCACAGTGCCCTACTCACACAGG	HERC5	ENSG00000138646	0.6743977780023188	[465]	[235,614,NaN]	5	hSpCas9	negative selection	10083975
88467152	88467175	4	-	27869803	HPAFII	viability after 31 days	TCACTGGAAGCGGCATCAGCTGG	HERC5	ENSG00000138646	1.5843501100830595	[184]	[184,448,NaN]	9	hSpCas9	negative selection	10083976
88469224	88469247	4	+	27869803	HPAFII	viability after 31 days	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.6175025362668545	[569]	[619,349,NaN]	4	hSpCas9	negative selection	10083977
88457259	88457282	4	+	28162770	P31FUJ	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.9202771255900106	[133]	[297]	9	hSpCas9	negative selection	10168402
88462150	88462173	4	+	28162770	P31FUJ	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.8075869196772917	[316]	[651]	8	hSpCas9	negative selection	10168403
88469224	88469247	4	+	28162770	P31FUJ	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.06569221857912022	[398]	[447]	0	hSpCas9	negative selection	10168404
88457277	88457300	4	+	28162770	P31FUJ	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.9360846723242962	[126]	[38]	-8	hSpCas9	negative selection	10168405
88457456	88457479	4	+	28162770	P31FUJ	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.7545609699076958	[171]	[340]	8	hSpCas9	negative selection	10168406
88462323	88462346	4	+	28162770	P31FUJ	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.20689734909873447	[86]	[117]	2	hSpCas9	negative selection	10168407
88467162	88467185	4	-	28162770	P31FUJ	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.38908686530513503	[359]	[553]	4	hSpCas9	negative selection	10168408
88457430	88457453	4	+	28162770	P31FUJ	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.5946183406973311	[101]	[180]	6	hSpCas9	negative selection	10168409
88462212	88462235	4	-	28162770	P31FUJ	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.14480688828699617	[614]	[798]	1	hSpCas9	negative selection	10168410
88463960	88463983	4	+	28162770	P31FUJ	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.48708987639288615	[424]	[699]	5	hSpCas9	negative selection	10168411
88457259	88457282	4	+	28162770	TF1	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10337768
88462150	88462173	4	+	28162770	TF1	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	NaN	[NaN]	[224]	1	hSpCas9	negative selection	10337769
88469224	88469247	4	+	28162770	TF1	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	NaN	[NaN]	[274]	1	hSpCas9	negative selection	10337770
88457277	88457300	4	+	28162770	TF1	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10337771
88457456	88457479	4	+	28162770	TF1	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10337772
88462323	88462346	4	+	28162770	TF1	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10337773
88467162	88467185	4	-	28162770	TF1	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	NaN	[NaN]	[545]	1	hSpCas9	negative selection	10337774
88457430	88457453	4	+	28162770	TF1	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	NaN	[NaN]	[36]	1	hSpCas9	negative selection	10337775
88462212	88462235	4	-	28162770	TF1	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	NaN	[NaN]	[488]	1	hSpCas9	negative selection	10337776
88463960	88463983	4	+	28162770	TF1	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	NaN	[NaN]	[653]	1	hSpCas9	negative selection	10337777
88457259	88457282	4	+	28162770	SKM1	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.538745645755885	[43]	[112]	5	hSpCas9	negative selection	10507134
88462150	88462173	4	+	28162770	SKM1	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.923068945781256	[70]	[237]	8	hSpCas9	negative selection	10507135
88469224	88469247	4	+	28162770	SKM1	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.9190800046164327	[104]	[350]	8	hSpCas9	negative selection	10507136
88457277	88457300	4	+	28162770	SKM1	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-2.3625700793847084	[31]	[10]	-8	hSpCas9	negative selection	10507137
88457456	88457479	4	+	28162770	SKM1	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.5716621504642714	[50]	[133]	5	hSpCas9	negative selection	10507138
88462323	88462346	4	+	28162770	SKM1	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.06696698958925063	[26]	[49]	0	hSpCas9	negative selection	10507139
88467162	88467185	4	-	28162770	SKM1	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.44215586477072566	[106]	[256]	4	hSpCas9	negative selection	10507140
88457430	88457453	4	+	28162770	SKM1	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.11480447549080053	[34]	[66]	1	hSpCas9	negative selection	10507141
88462212	88462235	4	-	28162770	SKM1	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.6754979614488115	[135]	[383]	6	hSpCas9	negative selection	10507142
88463960	88463983	4	+	28162770	SKM1	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.4251586284633846	[98]	[234]	4	hSpCas9	negative selection	10507143
88457259	88457282	4	+	28162770	SKM1	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.538745645755885	[43]	[112]	5	hSpCas9	negative selection	10676500
88462150	88462173	4	+	28162770	SKM1	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.923068945781256	[70]	[237]	8	hSpCas9	negative selection	10676501
88469224	88469247	4	+	28162770	SKM1	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.9190800046164327	[104]	[350]	8	hSpCas9	negative selection	10676502
88457277	88457300	4	+	28162770	SKM1	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-2.3625700793847084	[31]	[10]	-8	hSpCas9	negative selection	10676503
88457456	88457479	4	+	28162770	SKM1	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.5716621504642714	[50]	[133]	5	hSpCas9	negative selection	10676504
88462323	88462346	4	+	28162770	SKM1	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.06696698958925063	[26]	[49]	0	hSpCas9	negative selection	10676505
88467162	88467185	4	-	28162770	SKM1	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.44215586477072566	[106]	[256]	4	hSpCas9	negative selection	10676506
88457430	88457453	4	+	28162770	SKM1	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.11480447549080053	[34]	[66]	1	hSpCas9	negative selection	10676507
88462212	88462235	4	-	28162770	SKM1	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.6754979614488115	[135]	[383]	6	hSpCas9	negative selection	10676508
88463960	88463983	4	+	28162770	SKM1	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.4251586284633846	[98]	[234]	4	hSpCas9	negative selection	10676509
88457259	88457282	4	+	28162770	PL21	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.7421499700259293	[124]	[90]	6	hSpCas9	negative selection	10845866
88462150	88462173	4	+	28162770	PL21	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.6545705520682511	[288]	[197]	5	hSpCas9	negative selection	10845867
88469224	88469247	4	+	28162770	PL21	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.36452643239020255	[347]	[194]	3	hSpCas9	negative selection	10845868
88457277	88457300	4	+	28162770	PL21	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.247319362481901	[119]	[21]	-7	hSpCas9	negative selection	10845869
88457456	88457479	4	+	28162770	PL21	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.643746265964935	[199]	[135]	5	hSpCas9	negative selection	10845870
88462323	88462346	4	+	28162770	PL21	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.8934782762552682	[93]	[75]	7	hSpCas9	negative selection	10845871
88467162	88467185	4	-	28162770	PL21	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.23978869114232004	[322]	[165]	2	hSpCas9	negative selection	10845872
88457430	88457453	4	+	28162770	PL21	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-0.2726133826458109	[135]	[48]	-2	hSpCas9	negative selection	10845873
88462212	88462235	4	-	28162770	PL21	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.2166277372778892	[347]	[175]	2	hSpCas9	negative selection	10845874
88463960	88463983	4	+	28162770	PL21	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	-0.5904070198817302	[383]	[110]	-4	hSpCas9	negative selection	10845875
88457259	88457282	4	+	28162770	P31FUJ	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.9202771255900106	[133]	[297]	9	hSpCas9	negative selection	11015232
88462150	88462173	4	+	28162770	P31FUJ	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.8075869196772917	[316]	[651]	8	hSpCas9	negative selection	11015233
88469224	88469247	4	+	28162770	P31FUJ	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	-0.06569221857912022	[398]	[447]	0	hSpCas9	negative selection	11015234
88457277	88457300	4	+	28162770	P31FUJ	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.9360846723242962	[126]	[38]	-8	hSpCas9	negative selection	11015235
88457456	88457479	4	+	28162770	P31FUJ	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.7545609699076958	[171]	[340]	8	hSpCas9	negative selection	11015236
88462323	88462346	4	+	28162770	P31FUJ	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.20689734909873447	[86]	[117]	2	hSpCas9	negative selection	11015237
88467162	88467185	4	-	28162770	P31FUJ	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.38908686530513503	[359]	[553]	4	hSpCas9	negative selection	11015238
88457430	88457453	4	+	28162770	P31FUJ	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.5946183406973311	[101]	[180]	6	hSpCas9	negative selection	11015239
88462212	88462235	4	-	28162770	P31FUJ	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.14480688828699617	[614]	[798]	1	hSpCas9	negative selection	11015240
88463960	88463983	4	+	28162770	P31FUJ	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.48708987639288615	[424]	[699]	5	hSpCas9	negative selection	11015241
88457259	88457282	4	+	28162770	OCIAML5	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.39729289807272017	[52]	[125]	3	hSpCas9	negative selection	11184598
88462150	88462173	4	+	28162770	OCIAML5	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.9629964463288703	[159]	[562]	8	hSpCas9	negative selection	11184599
88469224	88469247	4	+	28162770	OCIAML5	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.041942733447789315	[239]	[445]	0	hSpCas9	negative selection	11184600
88457277	88457300	4	+	28162770	OCIAML5	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-4.659421492921601	[41]	[2]	-9	hSpCas9	negative selection	11184601
88457456	88457479	4	+	28162770	OCIAML5	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.15447627500277517	[109]	[220]	1	hSpCas9	negative selection	11184602
88462323	88462346	4	+	28162770	OCIAML5	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.9426145211584964	[48]	[169]	7	hSpCas9	negative selection	11184603
88467162	88467185	4	-	28162770	OCIAML5	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.6007923938498141	[239]	[656]	5	hSpCas9	negative selection	11184604
88457430	88457453	4	+	28162770	OCIAML5	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.958777337273487	[58]	[206]	8	hSpCas9	negative selection	11184605
88462212	88462235	4	-	28162770	OCIAML5	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.10816290044340215	[330]	[643]	0	hSpCas9	negative selection	11184606
88463960	88463983	4	+	28162770	OCIAML5	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.4905929656074519	[303]	[770]	4	hSpCas9	negative selection	11184607
88457259	88457282	4	+	28162770	EOL1	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	-1.6494436113296183	[261]	[43]	-8	hSpCas9	negative selection	11353964
88462150	88462173	4	+	28162770	EOL1	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.1121747747463061	[431]	[245]	1	hSpCas9	negative selection	11353965
88469224	88469247	4	+	28162770	EOL1	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.4910594201855192	[681]	[504]	4	hSpCas9	negative selection	11353966
88457277	88457300	4	+	28162770	EOL1	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-0.5048450206853794	[201]	[74]	-4	hSpCas9	negative selection	11353967
88457456	88457479	4	+	28162770	EOL1	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.022452359542520617	[412]	[220]	0	hSpCas9	negative selection	11353968
88462323	88462346	4	+	28162770	EOL1	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	1.789798359457297	[156]	[285]	9	hSpCas9	negative selection	11353969
88467162	88467185	4	-	28162770	EOL1	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.7100174680070569	[426]	[367]	6	hSpCas9	negative selection	11353970
88457430	88457453	4	+	28162770	EOL1	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-1.3110804769226074	[145]	[30]	-7	hSpCas9	negative selection	11353971
88462212	88462235	4	-	28162770	EOL1	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	-0.558826857471463	[561]	[200]	-4	hSpCas9	negative selection	11353972
88463960	88463983	4	+	28162770	EOL1	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.39874005754928243	[441]	[306]	3	hSpCas9	negative selection	11353973
88457259	88457282	4	+	28162770	MOLM13	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.7378101729636126	[208]	[251]	5	hSpCas9	negative selection	11523330
88462150	88462173	4	+	28162770	MOLM13	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.36264622151724224	[397]	[369]	2	hSpCas9	negative selection	11523331
88469224	88469247	4	+	28162770	MOLM13	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.9068163130096624	[553]	[750]	7	hSpCas9	negative selection	11523332
88457277	88457300	4	+	28162770	MOLM13	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-2.3862597519919664	[187]	[25]	-8	hSpCas9	negative selection	11523333
88457456	88457479	4	+	28162770	MOLM13	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.5327891563376737	[325]	[340]	4	hSpCas9	negative selection	11523334
88462323	88462346	4	+	28162770	MOLM13	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.40515362619661643	[140]	[134]	3	hSpCas9	negative selection	11523335
88467162	88467185	4	-	28162770	MOLM13	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	-0.49122614382541097	[660]	[339]	-3	hSpCas9	negative selection	11523336
88457430	88457453	4	+	28162770	MOLM13	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-0.28834454632640627	[200]	[118]	-2	hSpCas9	negative selection	11523337
88462212	88462235	4	-	28162770	MOLM13	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.0829376084550264	[695]	[532]	0	hSpCas9	negative selection	11523338
88463960	88463983	4	+	28162770	MOLM13	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.16347904791524592	[572]	[463]	1	hSpCas9	negative selection	11523339
88457259	88457282	4	+	28162770	HEL	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	1.488705203327936	[157]	[283]	9	hSpCas9	negative selection	11692696
88462150	88462173	4	+	28162770	HEL	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	-0.6769849919602753	[326]	[130]	-4	hSpCas9	negative selection	11692697
88469224	88469247	4	+	28162770	HEL	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.6948075521431947	[516]	[535]	6	hSpCas9	negative selection	11692698
88457277	88457300	4	+	28162770	HEL	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-2.3505665154256348	[214]	[26]	-8	hSpCas9	negative selection	11692699
88457456	88457479	4	+	28162770	HEL	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.8594176021424113	[252]	[293]	7	hSpCas9	negative selection	11692700
88462323	88462346	4	+	28162770	HEL	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	1.1947867102487781	[132]	[194]	9	hSpCas9	negative selection	11692701
88467162	88467185	4	-	28162770	HEL	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.34176594350661993	[392]	[318]	3	hSpCas9	negative selection	11692702
88457430	88457453	4	+	28162770	HEL	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-0.8945269266895028	[118]	[40]	-5	hSpCas9	negative selection	11692703
88462212	88462235	4	-	28162770	HEL	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.3724728569354874	[479]	[397]	3	hSpCas9	negative selection	11692704
88463960	88463983	4	+	28162770	HEL	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.8160134867721138	[477]	[538]	7	hSpCas9	negative selection	11692705
88457259	88457282	4	+	28162770	MV411	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.8736227142304446	[137]	[212]	7	hSpCas9	negative selection	11862062
88462150	88462173	4	+	28162770	MV411	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.7068691694200728	[247]	[340]	6	hSpCas9	negative selection	11862063
88469224	88469247	4	+	28162770	MV411	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.4061352968018336	[343]	[383]	3	hSpCas9	negative selection	11862064
88457277	88457300	4	+	28162770	MV411	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.7119204647198787	[174]	[44]	-8	hSpCas9	negative selection	11862065
88457456	88457479	4	+	28162770	MV411	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.9229431432574485	[210]	[336]	8	hSpCas9	negative selection	11862066
88462323	88462346	4	+	28162770	MV411	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.5037773040425608	[71]	[85]	4	hSpCas9	negative selection	11862067
88467162	88467185	4	-	28162770	MV411	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	-0.06158306032519889	[305]	[246]	0	hSpCas9	negative selection	11862068
88457430	88457453	4	+	28162770	MV411	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	0.4199047467875408	[125]	[141]	4	hSpCas9	negative selection	11862069
88462212	88462235	4	-	28162770	MV411	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.3832799401627893	[394]	[433]	3	hSpCas9	negative selection	11862070
88463960	88463983	4	+	28162770	MV411	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.42431531286685453	[321]	[363]	4	hSpCas9	negative selection	11862071
88457259	88457282	4	+	28162770	MONOMAC1	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.3981214207674908	[93]	[141]	4	hSpCas9	negative selection	12031428
88462150	88462173	4	+	28162770	MONOMAC1	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.5134565357454615	[164]	[269]	5	hSpCas9	negative selection	12031429
88469224	88469247	4	+	28162770	MONOMAC1	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.44259062925998416	[327]	[510]	4	hSpCas9	negative selection	12031430
88457277	88457300	4	+	28162770	MONOMAC1	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.9282200886317538	[82]	[24]	-8	hSpCas9	negative selection	12031431
88457456	88457479	4	+	28162770	MONOMAC1	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.08377226050221626	[120]	[146]	0	hSpCas9	negative selection	12031432
88462323	88462346	4	+	28162770	MONOMAC1	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.5833967756827617	[84]	[145]	5	hSpCas9	negative selection	12031433
88467162	88467185	4	-	28162770	MONOMAC1	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.37915544403387036	[219]	[327]	4	hSpCas9	negative selection	12031434
88457430	88457453	4	+	28162770	MONOMAC1	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-0.9813081560041166	[92]	[53]	-6	hSpCas9	negative selection	12031435
88462212	88462235	4	-	28162770	MONOMAC1	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.20905169549180713	[282]	[374]	2	hSpCas9	negative selection	12031436
88463960	88463983	4	+	28162770	MONOMAC1	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	0.03903051117397072	[224]	[264]	0	hSpCas9	negative selection	12031437
88457259	88457282	4	+	28162770	OCIAML2	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	0.9647563194284852	[21]	[237]	8	hSpCas9	negative selection	12200794
88462150	88462173	4	+	28162770	OCIAML2	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	0.6275937108459622	[54]	[470]	6	hSpCas9	negative selection	12200795
88469224	88469247	4	+	28162770	OCIAML2	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.5317410792205859	[75]	[608]	5	hSpCas9	negative selection	12200796
88457277	88457300	4	+	28162770	OCIAML2	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	-1.9300614438794585	[21]	[31]	-8	hSpCas9	negative selection	12200797
88457456	88457479	4	+	28162770	OCIAML2	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.296924088757468	[41]	[285]	3	hSpCas9	negative selection	12200798
88462323	88462346	4	+	28162770	OCIAML2	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.266335768924045	[14]	[99]	2	hSpCas9	negative selection	12200799
88467162	88467185	4	-	28162770	OCIAML2	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.9834386086280432	[48]	[536]	8	hSpCas9	negative selection	12200800
88457430	88457453	4	+	28162770	OCIAML2	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-0.5961607073260202	[23]	[87]	-4	hSpCas9	negative selection	12200801
88462212	88462235	4	-	28162770	OCIAML2	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.26208629592268706	[67]	[451]	2	hSpCas9	negative selection	12200802
88463960	88463983	4	+	28162770	OCIAML2	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	-0.1530147232258814	[66]	[333]	-1	hSpCas9	negative selection	12200803
88457259	88457282	4	+	28162770	OCIAML3	viability	GCAAAGCGGCGATGGAGCGGAGG	HERC5	ENSG00000138646	-1.155886527932278	[61]	[83]	-7	hSpCas9	negative selection	12370160
88462150	88462173	4	+	28162770	OCIAML3	viability	CCTGGGGACAGAACCTGCATGGG	HERC5	ENSG00000138646	-0.5236183124327654	[89]	[188]	-4	hSpCas9	negative selection	12370161
88469224	88469247	4	+	28162770	OCIAML3	viability	CTGATGTGGAGACTAAACGGTGG	HERC5	ENSG00000138646	0.2555007331483865	[105]	[381]	2	hSpCas9	negative selection	12370162
88457277	88457300	4	+	28162770	OCIAML3	viability	GGAGGTCGCGGAGGAAGTCGCGG	HERC5	ENSG00000138646	0.2935176304174243	[29]	[110]	2	hSpCas9	negative selection	12370163
88457456	88457479	4	+	28162770	OCIAML3	viability	CTCGCGGTCTTGGAACGCGGCGG	HERC5	ENSG00000138646	0.40051722960968583	[65]	[262]	4	hSpCas9	negative selection	12370164
88462323	88462346	4	+	28162770	OCIAML3	viability	GAATGTGGACAACTAGGCCTGGG	HERC5	ENSG00000138646	0.6539198731194222	[15]	[75]	6	hSpCas9	negative selection	12370165
88467162	88467185	4	-	28162770	OCIAML3	viability	GATGATACTTTCACTGGAAGCGG	HERC5	ENSG00000138646	0.6283847810122847	[89]	[419]	6	hSpCas9	negative selection	12370166
88457430	88457453	4	+	28162770	OCIAML3	viability	GCCAACTCTGCTGCTCGCCGGGG	HERC5	ENSG00000138646	-0.18875116183790452	[36]	[97]	-1	hSpCas9	negative selection	12370167
88462212	88462235	4	-	28162770	OCIAML3	viability	GCGAGGTGCTCCACAATCTGTGG	HERC5	ENSG00000138646	0.4991017640673181	[89]	[383]	4	hSpCas9	negative selection	12370168
88463960	88463983	4	+	28162770	OCIAML3	viability	AGAGTGACTCAGATAGCATGTGG	HERC5	ENSG00000138646	-0.030418790395573714	[135]	[401]	0	hSpCas9	negative selection	12370169