Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:11148
• Symbol:HHLA2
• Description:HERV-H LTR-associating 2

DataSource: http://genomecrispr.dkfz.de/#!/results/HHLA2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
108362353	108362376	3	+	26472758	Jiyoye	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.33109298867504444	[291]	[276]	2	hSpCas9	negative selection	70601
108357933	108357956	3	+	26472758	Jiyoye	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	-0.4042150537868874	[178]	[101]	-3	hSpCas9	negative selection	70602
108362393	108362416	3	-	26472758	Jiyoye	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	-2.2024491734495517	[176]	[28]	-8	hSpCas9	negative selection	70603
108353755	108353778	3	+	26472758	Jiyoye	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	-0.2847023231317946	[209]	[129]	-2	hSpCas9	negative selection	70604
108376506	108376529	3	-	26472758	Jiyoye	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	1.0215216890081238	[80]	[123]	6	hSpCas9	negative selection	70605
108353690	108353713	3	+	26472758	Jiyoye	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.2479767866566196	[200]	[179]	2	hSpCas9	negative selection	70606
108355349	108355372	3	+	26472758	Jiyoye	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	0.0446053021211652	[17]	[13]	0	hSpCas9	negative selection	70607
108362425	108362448	3	+	26472758	Jiyoye	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.7425717379988087	[212]	[95]	-5	hSpCas9	negative selection	70608
108375747	108375770	3	+	26472758	Jiyoye	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-0.4408215250490768	[26]	[14]	-3	hSpCas9	negative selection	70609
108355192	108355215	3	-	26472758	Jiyoye	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.5840531435899528	[137]	[155]	4	hSpCas9	negative selection	70610
108362353	108362376	3	+	26472758	KBM7	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.7064390463115775	[1072,1045]	[885,752]	7	hSpCas9	negative selection	261719
108357933	108357956	3	+	26472758	KBM7	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.5513751436641576	[496,327]	[219,332]	6	hSpCas9	negative selection	261720
108362393	108362416	3	-	26472758	KBM7	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	-0.17466923579574178	[169,192]	[95,58]	-2	hSpCas9	negative selection	261721
108353755	108353778	3	+	26472758	KBM7	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.5499509541998313	[560,423]	[215,442]	6	hSpCas9	negative selection	261722
108376506	108376529	3	-	26472758	KBM7	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	-1.0934921156108537	[603,567]	[103,151]	-7	hSpCas9	negative selection	261723
108353690	108353713	3	+	26472758	KBM7	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.5385721484426385	[857,673]	[551,489]	6	hSpCas9	negative selection	261724
108355349	108355372	3	+	26472758	KBM7	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	-0.4377772004148506	[112,111]	[34,42]	-4	hSpCas9	negative selection	261725
108362425	108362448	3	+	26472758	KBM7	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.24431351902051313	[819,597]	[305,465]	2	hSpCas9	negative selection	261726
108375747	108375770	3	+	26472758	KBM7	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-0.2478357331420682	[84,35]	[30,15]	-2	hSpCas9	negative selection	261727
108355192	108355215	3	-	26472758	KBM7	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.7718584205422544	[728,740]	[603,583]	8	hSpCas9	negative selection	261728
108362353	108362376	3	+	26472758	Raji	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	1.351488212672542	[357]	[211]	9	hSpCas9	negative selection	452837
108357933	108357956	3	+	26472758	Raji	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.6383870527007683	[226]	[81]	6	hSpCas9	negative selection	452838
108362393	108362416	3	-	26472758	Raji	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.49594882329125234	[54]	[17]	5	hSpCas9	negative selection	452839
108353755	108353778	3	+	26472758	Raji	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.45337939022279194	[213]	[67]	4	hSpCas9	negative selection	452840
108376506	108376529	3	-	26472758	Raji	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.3562040819876925	[339]	[100]	3	hSpCas9	negative selection	452841
108353690	108353713	3	+	26472758	Raji	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.6098838759027828	[383]	[135]	6	hSpCas9	negative selection	452842
108355349	108355372	3	+	26472758	Raji	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	2.3188876405673113	[18]	[21]	9	hSpCas9	negative selection	452843
108362425	108362448	3	+	26472758	Raji	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.6214147379212082	[410]	[61]	-5	hSpCas9	negative selection	452844
108375747	108375770	3	+	26472758	Raji	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-0.6295820587926069	[59]	[8]	-5	hSpCas9	negative selection	452845
108355192	108355215	3	-	26472758	Raji	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	-0.3504670474442174	[455]	[82]	-3	hSpCas9	negative selection	452846
108362353	108362376	3	+	26472758	K562	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.1529625714359486	[813]	[763]	1	hSpCas9	negative selection	643955
108357933	108357956	3	+	26472758	K562	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	1.3108703769962835	[296]	[621]	9	hSpCas9	negative selection	643956
108362393	108362416	3	-	26472758	K562	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	1.2609699039302948	[129]	[262]	9	hSpCas9	negative selection	643957
108353755	108353778	3	+	26472758	K562	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.9213037178286425	[455]	[728]	7	hSpCas9	negative selection	643958
108376506	108376529	3	-	26472758	K562	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.6011372677337835	[548]	[702]	5	hSpCas9	negative selection	643959
108353690	108353713	3	+	26472758	K562	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	1.1497640049082403	[684]	[1282]	8	hSpCas9	negative selection	643960
108355349	108355372	3	+	26472758	K562	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	1.1154322869463686	[75]	[138]	8	hSpCas9	negative selection	643961
108362425	108362448	3	+	26472758	K562	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	1.3182389609581182	[599]	[1262]	9	hSpCas9	negative selection	643962
108375747	108375770	3	+	26472758	K562	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-1.4608380067724211	[74]	[22]	-6	hSpCas9	negative selection	643963
108355192	108355215	3	-	26472758	K562	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.9174725580124599	[539]	[860]	7	hSpCas9	negative selection	643964
108353529	108353552	3	+	26627737	DLD1	viability	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	-0.1627441565232568	[503]	[163,103,150]	-2	hSpCas9	negative selection	818670
108353599	108353622	3	-	26627737	DLD1	viability	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	1.0833525800770514	[311]	[236,223,165]	8	hSpCas9	negative selection	818671
108353690	108353713	3	+	26627737	DLD1	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.4295681530901727	[587]	[106,185,120]	-4	hSpCas9	negative selection	818672
108355190	108355213	3	+	26627737	DLD1	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.18831137978454415	[247]	[43,145,78]	2	hSpCas9	negative selection	818673
108355342	108355365	3	+	26627737	DLD1	viability	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.38230760512882234	[622]	[410,256,114]	4	hSpCas9	negative selection	818674
108376526	108376549	3	-	26627737	DLD1	viability	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.2659228799996708	[1075]	[368,191,274]	-3	hSpCas9	negative selection	818675
108353529	108353552	3	+	26627737	GBM cells	viability after 5 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.0076201343281855904	[229]	[123,123]	0	hSpCas9	negative selection	900985
108353599	108353622	3	-	26627737	GBM cells	viability after 5 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.22906247657801615	[314]	[191,203]	3	hSpCas9	negative selection	900986
108353690	108353713	3	+	26627737	GBM cells	viability after 5 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.17957843343361368	[490]	[234,229]	-3	hSpCas9	negative selection	900987
108355190	108355213	3	+	26627737	GBM cells	viability after 5 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.19037668904599694	[200]	[114,130]	3	hSpCas9	negative selection	900988
108355342	108355365	3	+	26627737	GBM cells	viability after 5 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.16049906408240977	[497]	[320,275]	2	hSpCas9	negative selection	900989
108376526	108376549	3	-	26627737	GBM cells	viability after 5 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.016022177884549932	[271]	[134,159]	0	hSpCas9	negative selection	900990
108353529	108353552	3	+	26627737	GBM cells	viability after 13 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.21087789468965423	[229]	[187,108]	2	hSpCas9	negative selection	983300
108353599	108353622	3	-	26627737	GBM cells	viability after 13 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.4608107335522492	[314]	[280,197]	6	hSpCas9	negative selection	983301
108353690	108353713	3	+	26627737	GBM cells	viability after 13 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.19033364935047115	[490]	[297,180]	-2	hSpCas9	negative selection	983302
108355190	108355213	3	+	26627737	GBM cells	viability after 13 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5362414230013332	[200]	[193,128]	6	hSpCas9	negative selection	983303
108355342	108355365	3	+	26627737	GBM cells	viability after 13 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.25791843249338964	[497]	[305,336]	3	hSpCas9	negative selection	983304
108376526	108376549	3	-	26627737	GBM cells	viability after 13 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.19218909153297745	[271]	[145,186]	2	hSpCas9	negative selection	983305
108353529	108353552	3	+	26627737	GBM cells	viability after 21 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	-0.2800018059546982	[229]	[104,100]	-3	hSpCas9	negative selection	1065615
108353599	108353622	3	-	26627737	GBM cells	viability after 21 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.503394944330461	[314]	[263,222]	5	hSpCas9	negative selection	1065616
108353690	108353713	3	+	26627737	GBM cells	viability after 21 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.13150212272272965	[490]	[254,232]	-1	hSpCas9	negative selection	1065617
108355190	108355213	3	+	26627737	GBM cells	viability after 21 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.2173613266910035	[200]	[127,125]	2	hSpCas9	negative selection	1065618
108355342	108355365	3	+	26627737	GBM cells	viability after 21 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.36096214050719344	[497]	[359,335]	4	hSpCas9	negative selection	1065619
108376526	108376549	3	-	26627737	GBM cells	viability after 21 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.28809253547144265	[271]	[181,178]	3	hSpCas9	negative selection	1065620
108353529	108353552	3	+	26627737	RPE1	viability after 9 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.12265350871594394	[628]	[130,321]	0	hSpCas9	negative selection	1147930
108353599	108353622	3	-	26627737	RPE1	viability after 9 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.7410270945033562	[986]	[491,547]	5	hSpCas9	negative selection	1147931
108353690	108353713	3	+	26627737	RPE1	viability after 9 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.46786949537487016	[1328]	[309,288]	-3	hSpCas9	negative selection	1147932
108355190	108355213	3	+	26627737	RPE1	viability after 9 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4488688255763882	[657]	[278,283]	3	hSpCas9	negative selection	1147933
108355342	108355365	3	+	26627737	RPE1	viability after 9 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.416789623176764	[862]	[616,855]	7	hSpCas9	negative selection	1147934
108376526	108376549	3	-	26627737	RPE1	viability after 9 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.5493810420987671	[1441]	[266,361]	-4	hSpCas9	negative selection	1147935
108353529	108353552	3	+	26627737	RPE1	viability after 12 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.02474082927873611	[628]	[185,156]	0	hSpCas9	negative selection	1230245
108353599	108353622	3	-	26627737	RPE1	viability after 12 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.30222590259495685	[986]	[325,327]	2	hSpCas9	negative selection	1230246
108353690	108353713	3	+	26627737	RPE1	viability after 12 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.29542196050887815	[1328]	[339,238]	-2	hSpCas9	negative selection	1230247
108355190	108355213	3	+	26627737	RPE1	viability after 12 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.38019523904966146	[657]	[215,244]	2	hSpCas9	negative selection	1230248
108355342	108355365	3	+	26627737	RPE1	viability after 12 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.5865486705665255	[862]	[639,755]	8	hSpCas9	negative selection	1230249
108376526	108376549	3	-	26627737	RPE1	viability after 12 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.4605332982004672	[1441]	[367,189]	-3	hSpCas9	negative selection	1230250
108353529	108353552	3	+	26627737	RPE1	viability after 15 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.16214601090055802	[628]	[249,149]	1	hSpCas9	negative selection	1312560
108353599	108353622	3	-	26627737	RPE1	viability after 15 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.3402612618515167	[986]	[467,242]	2	hSpCas9	negative selection	1312561
108353690	108353713	3	+	26627737	RPE1	viability after 15 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-1.1851887712149343	[1328]	[174,155]	-6	hSpCas9	negative selection	1312562
108355190	108355213	3	+	26627737	RPE1	viability after 15 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.38706018874632314	[657]	[163,319]	2	hSpCas9	negative selection	1312563
108355342	108355365	3	+	26627737	RPE1	viability after 15 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.0030435562649882	[862]	[557,422]	6	hSpCas9	negative selection	1312564
108376526	108376549	3	-	26627737	RPE1	viability after 15 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.393804294455746	[1441]	[480,145]	-2	hSpCas9	negative selection	1312565
108353529	108353552	3	+	26627737	RPE1	viability after 18 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	-0.464288799900667	[628]	[94,152]	-3	hSpCas9	negative selection	1394875
108353599	108353622	3	-	26627737	RPE1	viability after 18 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.015774008014063368	[986]	[233,306]	0	hSpCas9	negative selection	1394876
108353690	108353713	3	+	26627737	RPE1	viability after 18 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.771853505529883	[1328]	[196,223]	-5	hSpCas9	negative selection	1394877
108355190	108355213	3	+	26627737	RPE1	viability after 18 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.42630080182775504	[657]	[212,265]	2	hSpCas9	negative selection	1394878
108355342	108355365	3	+	26627737	RPE1	viability after 18 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.9855341610399929	[862]	[479,440]	6	hSpCas9	negative selection	1394879
108376526	108376549	3	-	26627737	RPE1	viability after 18 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.7309034514014026	[1441]	[291,172]	-4	hSpCas9	negative selection	1394880
108353529	108353552	3	+	26627737	HeLa	viability after 8 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.5898413813056476	[312]	[166,121,309]	5	hSpCas9	negative selection	1477190
108353599	108353622	3	-	26627737	HeLa	viability after 8 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.7274601190298364	[335]	[342,230,178]	6	hSpCas9	negative selection	1477191
108353690	108353713	3	+	26627737	HeLa	viability after 8 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.1422366422418252	[508]	[397,226,148]	1	hSpCas9	negative selection	1477192
108355190	108355213	3	+	26627737	HeLa	viability after 8 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5692816526234818	[167]	[160,67,107]	5	hSpCas9	negative selection	1477193
108355342	108355365	3	+	26627737	HeLa	viability after 8 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.2418526704618822	[447]	[536,270,582]	8	hSpCas9	negative selection	1477194
108376526	108376549	3	-	26627737	HeLa	viability after 8 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.16727236725719663	[709]	[355,446,246]	1	hSpCas9	negative selection	1477195
108353529	108353552	3	+	26627737	HeLa	viability after 12 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.0054444294227022905	[312]	[172,89,131]	0	hSpCas9	negative selection	1559505
108353599	108353622	3	-	26627737	HeLa	viability after 12 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.4034941498284581	[335]	[333,139,85]	3	hSpCas9	negative selection	1559506
108353690	108353713	3	+	26627737	HeLa	viability after 12 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.721894722321837	[508]	[472,294,281]	6	hSpCas9	negative selection	1559507
108355190	108355213	3	+	26627737	HeLa	viability after 12 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.29458081484476	[167]	[166,215,122]	8	hSpCas9	negative selection	1559508
108355342	108355365	3	+	26627737	HeLa	viability after 12 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.228428009440089	[447]	[401,381,521]	8	hSpCas9	negative selection	1559509
108376526	108376549	3	-	26627737	HeLa	viability after 12 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.15056801707746315	[709]	[312,256,413]	1	hSpCas9	negative selection	1559510
108353529	108353552	3	+	26627737	HeLa	viability after 15 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.33304220431304266	[312]	[87,142,258]	3	hSpCas9	negative selection	1641820
108353599	108353622	3	-	26627737	HeLa	viability after 15 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.5993500757561747	[335]	[165,263,190]	5	hSpCas9	negative selection	1641821
108353690	108353713	3	+	26627737	HeLa	viability after 15 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.3051605681205386	[508]	[158,309,303]	2	hSpCas9	negative selection	1641822
108355190	108355213	3	+	26627737	HeLa	viability after 15 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.3882585281159652	[167]	[168,227,136]	8	hSpCas9	negative selection	1641823
108355342	108355365	3	+	26627737	HeLa	viability after 15 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.090911423218275	[447]	[426,167,584]	7	hSpCas9	negative selection	1641824
108376526	108376549	3	-	26627737	HeLa	viability after 15 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.013859138325210019	[709]	[316,195,367]	0	hSpCas9	negative selection	1641825
108353529	108353552	3	+	26627737	HeLa	viability after 18 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.30235362785905123	[312]	[55,113,258]	2	hSpCas9	negative selection	1724135
108353599	108353622	3	-	26627737	HeLa	viability after 18 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.5897998910697395	[335]	[105,221,190]	5	hSpCas9	negative selection	1724136
108353690	108353713	3	+	26627737	HeLa	viability after 18 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.29867374744190833	[508]	[108,250,303]	2	hSpCas9	negative selection	1724137
108355190	108355213	3	+	26627737	HeLa	viability after 18 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.3706462714494616	[167]	[112,183,136]	8	hSpCas9	negative selection	1724138
108355342	108355365	3	+	26627737	HeLa	viability after 18 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.0813534367970181	[447]	[283,135,584]	7	hSpCas9	negative selection	1724139
108376526	108376549	3	-	26627737	HeLa	viability after 18 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.02982576618989996	[709]	[199,156,367]	0	hSpCas9	negative selection	1724140
108353529	108353552	3	+	26627737	HCT116	viability after 6 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.29934861529928747	[675]	[133,128]	1	hSpCas9	negative selection	1806450
108353599	108353622	3	-	26627737	HCT116	viability after 6 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	1.0441484483969221	[535]	[263,123]	5	hSpCas9	negative selection	1806451
108353690	108353713	3	+	26627737	HCT116	viability after 6 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	2.0340095233420934	[880]	[213,761]	8	hSpCas9	negative selection	1806452
108355190	108355213	3	+	26627737	HCT116	viability after 6 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.149951840281767	[413]	[106,31]	-1	hSpCas9	negative selection	1806453
108355342	108355365	3	+	26627737	HCT116	viability after 6 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	-0.05630182575184328	[1203]	[250,143]	0	hSpCas9	negative selection	1806454
108376526	108376549	3	-	26627737	HCT116	viability after 6 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.7987466982149158	[1159]	[119,425]	4	hSpCas9	negative selection	1806455
108353529	108353552	3	+	26627737	HCT116	viability after 8 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.48503586446154423	[239]	[175,183,194]	5	hSpCas9	negative selection	1888765
108353599	108353622	3	-	26627737	HCT116	viability after 8 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.09827399134024645	[357]	[227,291,114]	1	hSpCas9	negative selection	1888766
108353690	108353713	3	+	26627737	HCT116	viability after 8 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.40233039037215457	[656]	[285,263,271]	-5	hSpCas9	negative selection	1888767
108355190	108355213	3	+	26627737	HCT116	viability after 8 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.7881412749306964	[127]	[131,146,86]	7	hSpCas9	negative selection	1888768
108355342	108355365	3	+	26627737	HCT116	viability after 8 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.5586818439097738	[339]	[318,264,244]	5	hSpCas9	negative selection	1888769
108376526	108376549	3	-	26627737	HCT116	viability after 8 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.37743735045665994	[354]	[313,244,204]	4	hSpCas9	negative selection	1888770
108353529	108353552	3	+	26627737	HCT116	viability after 9 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.22379210554101384	[675]	[269,163]	1	hSpCas9	negative selection	1971080
108353599	108353622	3	-	26627737	HCT116	viability after 9 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	-0.05889902337753619	[535]	[228,64]	0	hSpCas9	negative selection	1971081
108353690	108353713	3	+	26627737	HCT116	viability after 9 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.5307707734642129	[880]	[407,285]	4	hSpCas9	negative selection	1971082
108355190	108355213	3	+	26627737	HCT116	viability after 9 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.24025516648877837	[413]	[167,100]	1	hSpCas9	negative selection	1971083
108355342	108355365	3	+	26627737	HCT116	viability after 9 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.5758216847508679	[1203]	[629,359]	4	hSpCas9	negative selection	1971084
108376526	108376549	3	-	26627737	HCT116	viability after 9 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.5792363901273332	[1159]	[251,171]	-4	hSpCas9	negative selection	1971085
108353529	108353552	3	+	26627737	HCT116	viability after 12 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	-0.022087785327894183	[239]	[99,92,180]	0	hSpCas9	negative selection	2053395
108353599	108353622	3	-	26627737	HCT116	viability after 12 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.0657515018288512	[357]	[97,261,240]	0	hSpCas9	negative selection	2053396
108353690	108353713	3	+	26627737	HCT116	viability after 12 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.652306559652754	[656]	[198,183,276]	-6	hSpCas9	negative selection	2053397
108355190	108355213	3	+	26627737	HCT116	viability after 12 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.990646113245274	[127]	[88,136,178]	8	hSpCas9	negative selection	2053398
108355342	108355365	3	+	26627737	HCT116	viability after 12 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.4687944186666678	[339]	[299,196,238]	4	hSpCas9	negative selection	2053399
108376526	108376549	3	-	26627737	HCT116	viability after 12 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	1.2114307703680682	[354]	[419,468,408]	8	hSpCas9	negative selection	2053400
108353529	108353552	3	+	26627737	HCT116	viability after 15 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.09756287990279425	[239]	[115,208,113]	1	hSpCas9	negative selection	2135710
108353599	108353622	3	-	26627737	HCT116	viability after 15 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.10357892665725049	[357]	[201,203,253]	1	hSpCas9	negative selection	2135711
108353690	108353713	3	+	26627737	HCT116	viability after 15 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.7436049475008544	[656]	[147,240,276]	-6	hSpCas9	negative selection	2135712
108355190	108355213	3	+	26627737	HCT116	viability after 15 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.6103982136806053	[127]	[89,133,109]	5	hSpCas9	negative selection	2135713
108355342	108355365	3	+	26627737	HCT116	viability after 15 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.8680238927421748	[339]	[515,334,238]	7	hSpCas9	negative selection	2135714
108376526	108376549	3	-	26627737	HCT116	viability after 15 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.7635551599826607	[354]	[461,290,299]	6	hSpCas9	negative selection	2135715
108353529	108353552	3	+	26627737	HCT116	viability after 18 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.1771343438361049	[239]	[119,131,141]	1	hSpCas9	negative selection	2218025
108353599	108353622	3	-	26627737	HCT116	viability after 18 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	-0.3381197769326159	[357]	[135,117,158]	-3	hSpCas9	negative selection	2218026
108353690	108353713	3	+	26627737	HCT116	viability after 18 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-1.0255198926004043	[656]	[190,150,124]	-7	hSpCas9	negative selection	2218027
108355190	108355213	3	+	26627737	HCT116	viability after 18 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.2708780502862266	[127]	[81,62,79]	2	hSpCas9	negative selection	2218028
108355342	108355365	3	+	26627737	HCT116	viability after 18 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	1.1088056033635767	[339]	[390,437,222]	8	hSpCas9	negative selection	2218029
108376526	108376549	3	-	26627737	HCT116	viability after 18 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	0.8661445094486435	[354]	[492,208,239]	7	hSpCas9	negative selection	2218030
108344811	108344834	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTGTTGTTGTTGTTGTTGTTTAG	HHLA2	ENSG00000114455	-1.2553913082042603	[104,179]	[19,4]	-7	dCas9-VP64	positive selection	2401252
108311623	108311646	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGTGTAGCTTTCAAGGTTGG	HHLA2	ENSG00000114455	0.9736028450516295	[29,15]	[9,9]	4	dCas9-VP64	positive selection	2422107
108311652	108311675	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGTTTCTAGTTCTCAACTATGG	HHLA2	ENSG00000114455	2.01564557363023	[108,122]	[167,33]	7	dCas9-VP64	positive selection	2422108
108311603	108311626	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGGGTATTGGGCACAAGAAAGG	HHLA2	ENSG00000114455	0.3658626511989031	[62,129]	[15,39]	1	dCas9-VP64	positive selection	2422109
108364054	108364077	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATAGGTGCAGCAAACCACCAGGG	HHLA2	ENSG00000114455	9.45620005017045	[53,84]	[18082,3082]	9	dCas9-VP64	positive selection	2426887
108302328	108302351	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGGTAGGAGGTTGAACCCTGG	HHLA2	ENSG00000114455	-0.3867650614694722	[6,84]	[2,12]	-2	dCas9-VP64	positive selection	2441112
108302310	108302333	3	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGTAAATATTTTACCATCCAGG	HHLA2	ENSG00000114455	3.650738480510084	[191,193]	[13,1097]	9	dCas9-VP64	positive selection	2441113
108302286	108302309	3	-	25494202	A375	resistance to PLX-4720 (puromycin)	TTCCAGTAATCATGGTTTCCAGG	HHLA2	ENSG00000114455	0.10498772546252999	[374,100]	[98,7]	0	dCas9-VP64	positive selection	2441114
108344811	108344834	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTGTTGTTGTTGTTGTTGTTTAG	HHLA2	ENSG00000114455	-0.6691815338040683	[248,92]	[41,27]	-6	dCas9-VP64	positive selection	2496507
108311623	108311646	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGTGTAGCTTTCAAGGTTGG	HHLA2	ENSG00000114455	-0.5957653394823555	[184,64]	[30,22]	-6	dCas9-VP64	positive selection	2517362
108311652	108311675	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGTTTCTAGTTCTCAACTATGG	HHLA2	ENSG00000114455	-0.14710038311739393	[232,92]	[45,49]	-1	dCas9-VP64	positive selection	2517363
108311603	108311626	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGGGTATTGGGCACAAGAAAGG	HHLA2	ENSG00000114455	-0.4793332548503091	[134,84]	[15,33]	-5	dCas9-VP64	positive selection	2517364
108364054	108364077	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATAGGTGCAGCAAACCACCAGGG	HHLA2	ENSG00000114455	1.9932270680514117	[357,195]	[283,435]	8	dCas9-VP64	positive selection	2522142
108302328	108302351	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGGTAGGAGGTTGAACCCTGG	HHLA2	ENSG00000114455	0.6255754011120006	[22,64]	[13,28]	4	dCas9-VP64	positive selection	2536367
108302310	108302333	3	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGTAAATATTTTACCATCCAGG	HHLA2	ENSG00000114455	-0.4396244542933829	[285,210]	[99,21]	-4	dCas9-VP64	positive selection	2536368
108302286	108302309	3	-	25494202	A375	resistance to PLX-4720 (zeocin)	TTCCAGTAATCATGGTTTCCAGG	HHLA2	ENSG00000114455	2.902020486495854	[143,180]	[770,44]	9	dCas9-VP64	positive selection	2536369
108355191	108355214	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.2742052448891595	[3,4]	[4,1]	-4	hSpCas9	positive selection	2993203
108351848	108351871	3	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.1764828228650444	[4,4]	[4,4]	4	hSpCas9	positive selection	2993204
108353698	108353721	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTAAATTCCTTCGTCCAGAAGG	HHLA2	ENSG00000114455	-0.2972154609679463	[3,3]	[4,0]	-4	hSpCas9	positive selection	2993205
108355192	108355215	3	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.31070381857069795	[2,2]	[2,3]	6	hSpCas9	positive selection	2993206
108355191	108355214	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.13397672092544327	[3,3]	[3,1]	-2	hSpCas9	positive selection	3061061
108351848	108351871	3	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.002858857688960048	[4,4]	[4,2]	0	hSpCas9	positive selection	3061062
108353698	108353721	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTAAATTCCTTCGTCCAGAAGG	HHLA2	ENSG00000114455	-0.8277663097786855	[3,3]	[1,0]	-9	hSpCas9	positive selection	3061063
108355192	108355215	3	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.14034595165711544	[2,2]	[2,0]	2	hSpCas9	positive selection	3061064
108355190	108355213		+	24336571	A375	resistance to PLX after 7 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.14986614423772715	[36,46]	[34,38]	-5	hSpCas9	positive selection	3118978
108351843	108351866		-	24336571	A375	resistance to PLX after 7 days	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.19435916630623074	[12,13]	[14,15]	6	hSpCas9	positive selection	3118979
108355190	108355213		+	24336571	A375	resistance to PLX after 14 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.6071533893486243	[38,52]	[12,13]	-7	hSpCas9	positive selection	3176771
108351843	108351866		-	24336571	A375	resistance to PLX after 14 days	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.9627214352375657	[15,14]	[2,2]	-9	hSpCas9	positive selection	3176772
108355190	108355213		+	24336571	A375	viability after 7 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5089900474728004	[30]	[36,46]	7	hSpCas9	negative selection	3234564
108351843	108351866		-	24336571	A375	viability after 7 days	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.47842787241256335	[9]	[12,13]	7	hSpCas9	negative selection	3234565
108355190	108355213		+	24336571	A375	viability after 14 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.6780472680874081	[30]	[38,52]	8	hSpCas9	negative selection	3292357
108351843	108351866		-	24336571	A375	viability after 14 days	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.6703813330350226	[9]	[15,14]	8	hSpCas9	negative selection	3292358
108355190	108355213	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.194154286073186	[179,169]	[0,0]	-1	hSpCas9	positive selection	3353356
108355360	108355383	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	2.4499712893882313	[27,27]	[0,0]	8	hSpCas9	positive selection	3353357
108358006	108358029	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.04310234004535408	[146,149]	[0,0]	0	hSpCas9	positive selection	3353358
108358145	108358168	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.12804319450086865	[419,419]	[2,2]	0	hSpCas9	positive selection	3372551
108351843	108351866	3	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	2.7978945928085377	[21,21]	[0,0]	8	hSpCas9	positive selection	3372552
108351847	108351870	3	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	1.0478728458168853	[73,73]	[0,0]	5	hSpCas9	positive selection	3372553
108355190	108355213	3	+	26780180	HT29	viability (Avana library 4 designs)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.37028120184571	[]	[]	5	hSpCas9	negative selection	3430464
108351847	108351870	3	+	26780180	HT29	viability (Avana library 4 designs)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.76980406416441	[]	[]	3	hSpCas9	negative selection	3430465
108353698	108353721	3	-	26780180	HT29	viability (Avana library 4 designs)	TGTAAATTCCTTCGTCCAGAAGG	HHLA2	ENSG00000114455	1.02438725422725	[]	[]	4	hSpCas9	negative selection	3430466
108355192	108355215	3	-	26780180	HT29	viability (Avana library 4 designs)	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.440856717043994	[]	[]	1	hSpCas9	negative selection	3430467
108355190	108355213	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.118159681851987	[]	[]	0	hSpCas9	negative selection	3515638
108351847	108351870	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-4.10261431135855	[]	[]	-5	hSpCas9	negative selection	3515639
108353698	108353721	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAAATTCCTTCGTCCAGAAGG	HHLA2	ENSG00000114455	-1.39363673648056	[]	[]	-2	hSpCas9	negative selection	3515640
108355192	108355215	3	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	6.05120633195831	[]	[]	9	hSpCas9	negative selection	3515641
108355227	108355250	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTATCTCTGAAAACAACATGG	HHLA2	ENSG00000114455	-7.88146072993709	[]	[]	-7	hSpCas9	negative selection	3515642
108355360	108355383	3	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	5.25826591400594	[]	[]	8	hSpCas9	negative selection	3515643
108355190	108355213	3	+	26780180	A375	viability (Avana lentiGuide)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.677389284929337	[]	[]	0	hSpCas9	negative selection	3624297
108351847	108351870	3	+	26780180	A375	viability (Avana lentiGuide)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.049725939765323	[]	[]	0	hSpCas9	negative selection	3624298
108353698	108353721	3	-	26780180	A375	viability (Avana lentiGuide)	TGTAAATTCCTTCGTCCAGAAGG	HHLA2	ENSG00000114455	-6.62707787245884	[]	[]	-9	hSpCas9	negative selection	3624299
108355192	108355215	3	-	26780180	A375	viability (Avana lentiGuide)	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	3.05198767387221	[]	[]	3	hSpCas9	negative selection	3624300
108355227	108355250	3	+	26780180	A375	viability (Avana lentiGuide)	ACCTATCTCTGAAAACAACATGG	HHLA2	ENSG00000114455	-4.54515781729378	[]	[]	-7	hSpCas9	negative selection	3624301
108355360	108355383	3	+	26780180	A375	viability (Avana lentiGuide)	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	12.8786136528774	[]	[]	7	hSpCas9	negative selection	3624302
108355190	108355213	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.0221286293351719	[5]	[5,4]	0	hSpCas9	positive selection	3732956
108351847	108351870	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.26364706819776673	[8]	[6,5]	-4	hSpCas9	positive selection	3732957
108353698	108353721	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAAATTCCTTCGTCCAGAAGG	HHLA2	ENSG00000114455	-0.27954700883797545	[5]	[4,3]	-4	hSpCas9	positive selection	3732958
108355192	108355215	3	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.40723729621718097	[4]	[5,5]	9	hSpCas9	positive selection	3732959
108355227	108355250	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTATCTCTGAAAACAACATGG	HHLA2	ENSG00000114455	-0.9049403003930937	[6]	[2,2]	-8	hSpCas9	positive selection	3732960
108355360	108355383	3	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.12951238405015653	[4]	[4,4]	3	hSpCas9	positive selection	3732961
108355190	108355213	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.1922598615301393	[5]	[5,5]	5	hSpCas9	positive selection	3841563
108351847	108351870	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.12599683068651224	[6]	[6,3]	-2	hSpCas9	positive selection	3841564
108353698	108353721	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAAATTCCTTCGTCCAGAAGG	HHLA2	ENSG00000114455	0.19760504316817418	[5]	[5,4]	5	hSpCas9	positive selection	3841565
108355192	108355215	3	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.17414455983830457	[4]	[4,3]	4	hSpCas9	positive selection	3841566
108355227	108355250	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTATCTCTGAAAACAACATGG	HHLA2	ENSG00000114455	0.4179721446335235	[5]	[6,6]	9	hSpCas9	positive selection	3841567
108355360	108355383	3	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.1920364961206765	[4]	[4,4]	5	hSpCas9	positive selection	3841568
108355360	108355383	3	+	26780180	A375	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	1.24593323856513	[]	[]	6	hSpCas9	negative selection	3947631
108358145	108358168	3	-	26780180	A375	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.406077809813673	[]	[]	1	hSpCas9	negative selection	3947632
108355190	108355213	3	+	26780180	A375	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.898068249360964	[]	[]	4	hSpCas9	negative selection	3947633
108351847	108351870	3	+	26780180	A375	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	1.38561813815106	[]	[]	7	hSpCas9	negative selection	3947634
108358006	108358029	3	+	26780180	A375	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.515103917619182	[]	[]	1	hSpCas9	negative selection	3947635
108351843	108351866	3	-	26780180	A375	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.285699155056491	[]	[]	0	hSpCas9	negative selection	3947636
108355360	108355383	3	+	26780180	HT29	viability (GeCKOv2 library)	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	1.09648331631573	[]	[]	5	hSpCas9	negative selection	4055597
108358145	108358168	3	-	26780180	HT29	viability (GeCKOv2 library)	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.71693974774227	[]	[]	2	hSpCas9	negative selection	4055598
108355190	108355213	3	+	26780180	HT29	viability (GeCKOv2 library)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.82899791300555	[]	[]	3	hSpCas9	negative selection	4055599
108351847	108351870	3	+	26780180	HT29	viability (GeCKOv2 library)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	1.02758577413817	[]	[]	5	hSpCas9	negative selection	4055600
108358006	108358029	3	+	26780180	HT29	viability (GeCKOv2 library)	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.261628609942767	[]	[]	0	hSpCas9	negative selection	4055601
108351843	108351866	3	-	26780180	HT29	viability (GeCKOv2 library)	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.427358735173334	[]	[]	1	hSpCas9	negative selection	4055602
108355190	108355213	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.11242376093120077	[5]	[3,3]	3	hSpCas9	positive selection	4142450
108351843	108351866	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.29248174454890974	[3]	[2,1]	-6	hSpCas9	positive selection	4142451
108355190	108355213	3	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.0326828652245268	[4]	[2,3,5,4]	7	hSpCas9	positive selection	4206472
108351843	108351866	3	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.4211343664596791	[4]	[0,1,1,0]	-6	hSpCas9	positive selection	4206473
108355190	108355213	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5580930846335267	[3]	[4,3]	9	hSpCas9	positive selection	4274949
108355360	108355383	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.3746361638828899	[1]	[1,0]	-7	hSpCas9	positive selection	4274950
108358006	108358029	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.3044947249229385	[3]	[3,2]	6	hSpCas9	positive selection	4274951
108358145	108358168	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.13665400460098825	[4]	[4,2]	2	hSpCas9	positive selection	4339210
108351843	108351866	3	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.18931302605813305	[0]	[0,0]	-4	hSpCas9	positive selection	4339211
108351847	108351870	3	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.21346191206773948	[2]	[2,0]	-4	hSpCas9	positive selection	4339212
108353691	108353713	3	+	27760321	OCIAML3	viability	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.3920653967184561	[305,277]	[90,281]	-4	hSpCas9	negative selection	4406836
108353721	108353743	3	-	27760321	OCIAML3	viability	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	0.693044916603311	[320,242]	[344,364]	7	hSpCas9	negative selection	4406837
108353744	108353766	3	+	27760321	OCIAML3	viability	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	-0.5170612040344169	[42,40]	[12,35]	-5	hSpCas9	negative selection	4406838
108355191	108355213	3	+	27760321	OCIAML3	viability	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.8869533086006325	[211,182]	[194,401]	8	hSpCas9	negative selection	4406839
108358015	108358037	3	-	27760321	OCIAML3	viability	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-1.3477442217945488	[207,193]	[66,54]	-8	hSpCas9	negative selection	4406840
108353691	108353713	3	+	27760321	OCIAML2	viability	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.8702774486590903	[305,277]	[333,559]	9	hSpCas9	negative selection	4490299
108353721	108353743	3	-	27760321	OCIAML2	viability	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	0.682558423197269	[320,242]	[231,535]	8	hSpCas9	negative selection	4490300
108353744	108353766	3	+	27760321	OCIAML2	viability	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	1.125596760764306	[42,40]	[81,63]	9	hSpCas9	negative selection	4490301
108355191	108355213	3	+	27760321	OCIAML2	viability	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4287045873933911	[211,182]	[229,193]	6	hSpCas9	negative selection	4490302
108358015	108358037	3	-	27760321	OCIAML2	viability	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-0.8580204481941454	[207,193]	[84,95]	-7	hSpCas9	negative selection	4490303
108353691	108353713	3	+	27760321	MV411	viability	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.6386159194650832	[305,277]	[290,312]	5	hSpCas9	negative selection	4573762
108353721	108353743	3	-	27760321	MV411	viability	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	1.0886225927308921	[320,242]	[356,445]	7	hSpCas9	negative selection	4573763
108353744	108353766	3	+	27760321	MV411	viability	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	-0.6256944726501477	[42,40]	[1,41]	-4	hSpCas9	negative selection	4573764
108355191	108355213	3	+	27760321	MV411	viability	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	-0.16149063872068847	[211,182]	[126,99]	-1	hSpCas9	negative selection	4573765
108358015	108358037	3	-	27760321	MV411	viability	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	0.32843326075911494	[207,193]	[190,129]	2	hSpCas9	negative selection	4573766
108353691	108353713	3	+	27760321	HL60	viability	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.08627571738186224	[305,277]	[221,285]	1	hSpCas9	negative selection	4657225
108353721	108353743	3	-	27760321	HL60	viability	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	0.10206002625517274	[320,242]	[236,253]	1	hSpCas9	negative selection	4657226
108353744	108353766	3	+	27760321	HL60	viability	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	0.7678872281020985	[42,40]	[74,40]	8	hSpCas9	negative selection	4657227
108355191	108355213	3	+	27760321	HL60	viability	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.38338715543176727	[211,182]	[221,196]	5	hSpCas9	negative selection	4657228
108358015	108358037	3	-	27760321	HL60	viability	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-0.38147530210254743	[207,193]	[178,69]	-4	hSpCas9	negative selection	4657229
108353691	108353713	3	+	27760321	HT1080	viability	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.3351810826456385	[277,216]	[91,62]	-1	hSpCas9	negative selection	4740688
108353721	108353743	3	-	27760321	HT1080	viability	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	-1.0659239345021463	[242,189]	[55,24]	-4	hSpCas9	negative selection	4740689
108353744	108353766	3	+	27760321	HT1080	viability	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	-3.298996753167418	[40,31]	[0,1]	-7	hSpCas9	negative selection	4740690
108355191	108355213	3	+	27760321	HT1080	viability	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4723955892229664	[182,142]	[49,133]	2	hSpCas9	negative selection	4740691
108358015	108358037	3	-	27760321	HT1080	viability	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	0.2696966666185955	[193,151]	[0,172]	1	hSpCas9	negative selection	4740692
108353691	108353713	3	+	27760321	HT29	viability after 7 days	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.3560633077718627	[277,216]	[268,344,137]	-5	hSpCas9	negative selection	4824151
108353721	108353743	3	-	27760321	HT29	viability after 7 days	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	-0.14958319117843322	[242,189]	[233,133,377]	-2	hSpCas9	negative selection	4824152
108353744	108353766	3	+	27760321	HT29	viability after 7 days	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	0.27637038350461074	[40,31]	[30,86,48]	4	hSpCas9	negative selection	4824153
108355191	108355213	3	+	27760321	HT29	viability after 7 days	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.8779602619725777	[182,142]	[438,349,373]	9	hSpCas9	negative selection	4824154
108358015	108358037	3	-	27760321	HT29	viability after 7 days	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-1.998359849555031	[193,151]	[28,104,29]	-9	hSpCas9	negative selection	4824155
108353691	108353713	3	+	27760321	HT29	viability after 25 days	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.08665098797049486	[277,216]	[305,166,441]	0	hSpCas9	negative selection	4907614
108353721	108353743	3	-	27760321	HT29	viability after 25 days	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	-0.12628554500304545	[242,189]	[205,162,321]	-1	hSpCas9	negative selection	4907615
108353744	108353766	3	+	27760321	HT29	viability after 25 days	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	-0.4549684574001498	[40,31]	[32,36,19]	-4	hSpCas9	negative selection	4907616
108355191	108355213	3	+	27760321	HT29	viability after 25 days	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.14107217278570205	[182,142]	[150,300,162]	1	hSpCas9	negative selection	4907617
108358015	108358037	3	-	27760321	HT29	viability after 25 days	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-0.9564412501597559	[193,151]	[62,82,168]	-6	hSpCas9	negative selection	4907618
108353691	108353713	3	+	27760321	HT29	viability after 22 days	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.2189306500644198	[277,216]	[127,497,378]	2	hSpCas9	negative selection	4991077
108353721	108353743	3	-	27760321	HT29	viability after 22 days	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	-0.09297095937473365	[242,189]	[223,177,302]	-1	hSpCas9	negative selection	4991078
108353744	108353766	3	+	27760321	HT29	viability after 22 days	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	0.29142474981971	[40,31]	[20,56,77]	3	hSpCas9	negative selection	4991079
108355191	108355213	3	+	27760321	HT29	viability after 22 days	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5555915936539761	[182,142]	[171,359,301]	6	hSpCas9	negative selection	4991080
108358015	108358037	3	-	27760321	HT29	viability after 22 days	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-0.7459989573750339	[193,151]	[176,87,90]	-6	hSpCas9	negative selection	4991081
108353691	108353713	3	+	27760321	HT29	viability after 19 days	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.19331844491877748	[277,216]	[344,197,425]	1	hSpCas9	negative selection	5074540
108353721	108353743	3	-	27760321	HT29	viability after 19 days	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	-0.6194450016705559	[242,189]	[210,151,126]	-5	hSpCas9	negative selection	5074541
108353744	108353766	3	+	27760321	HT29	viability after 19 days	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	-0.3815516608801377	[40,31]	[0,9,79]	-4	hSpCas9	negative selection	5074542
108355191	108355213	3	+	27760321	HT29	viability after 19 days	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.8359144008711685	[182,142]	[332,274,387]	8	hSpCas9	negative selection	5074543
108358015	108358037	3	-	27760321	HT29	viability after 19 days	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-1.1995325867384268	[193,151]	[99,129,31]	-7	hSpCas9	negative selection	5074544
108353691	108353713	3	+	27760321	HT29	viability after 16 days	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.11824699340668332	[277,216]	[322,175,407]	1	hSpCas9	negative selection	5158003
108353721	108353743	3	-	27760321	HT29	viability after 16 days	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	0.3872297773698689	[242,189]	[272,136,540]	4	hSpCas9	negative selection	5158004
108353744	108353766	3	+	27760321	HT29	viability after 16 days	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	-0.9483788561588815	[40,31]	[0,4,55]	-7	hSpCas9	negative selection	5158005
108355191	108355213	3	+	27760321	HT29	viability after 16 days	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.6531558934278185	[182,142]	[225,272,355]	7	hSpCas9	negative selection	5158006
108358015	108358037	3	-	27760321	HT29	viability after 16 days	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-1.5778117521719488	[193,151]	[31,81,76]	-8	hSpCas9	negative selection	5158007
108353691	108353713	3	+	27760321	HT29	viability after 13 days	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.2174397654160134	[277,216]	[177,196,358]	-3	hSpCas9	negative selection	5241466
108353721	108353743	3	-	27760321	HT29	viability after 13 days	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	0.41145572315606194	[242,189]	[267,376,355]	5	hSpCas9	negative selection	5241467
108353744	108353766	3	+	27760321	HT29	viability after 13 days	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	0.18456463091534525	[40,31]	[43,62,37]	2	hSpCas9	negative selection	5241468
108355191	108355213	3	+	27760321	HT29	viability after 13 days	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.26794479396764936	[182,142]	[204,179,293]	3	hSpCas9	negative selection	5241469
108358015	108358037	3	-	27760321	HT29	viability after 13 days	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-0.5781964076053812	[193,151]	[216,65,120]	-6	hSpCas9	negative selection	5241470
108353691	108353713	3	+	27760321	HT29	viability after 10 days	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.1116419775142925	[277,216]	[275,330,252]	-1	hSpCas9	negative selection	5324929
108353721	108353743	3	-	27760321	HT29	viability after 10 days	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	0.01318891692666413	[242,189]	[290,235,289]	0	hSpCas9	negative selection	5324930
108353744	108353766	3	+	27760321	HT29	viability after 10 days	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	-0.1399368159046417	[40,31]	[29,44,48]	-2	hSpCas9	negative selection	5324931
108355191	108355213	3	+	27760321	HT29	viability after 10 days	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.061864085692937554	[182,142]	[123,305,209]	0	hSpCas9	negative selection	5324932
108358015	108358037	3	-	27760321	HT29	viability after 10 days	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-0.43587073440116786	[193,151]	[99,183,194]	-5	hSpCas9	negative selection	5324933
108353691	108353713	3	+	27760321	MOLM13	viability	GAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.7956890521817656	[305,277]	[32,500]	5	hSpCas9	negative selection	5408392
108353721	108353743	3	-	27760321	MOLM13	viability	ATTGCTGTTCCTACATAGCAGG	HHLA2	ENSG00000114455	2.4078480329777103	[320,242]	[305,1289]	9	hSpCas9	negative selection	5408393
108353744	108353766	3	+	27760321	MOLM13	viability	CAAGTGATTACAAACAAAGTGG	HHLA2	ENSG00000114455	2.793885053843963	[42,40]	[331,21]	9	hSpCas9	negative selection	5408394
108355191	108355213	3	+	27760321	MOLM13	viability	TCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.8615116628715769	[211,182]	[256,154]	6	hSpCas9	negative selection	5408395
108358015	108358037	3	-	27760321	MOLM13	viability	TCTTTGTTCCATGAGAATCGGG	HHLA2	ENSG00000114455	-0.30007089368924067	[207,193]	[69,110]	-2	hSpCas9	negative selection	5408396
108296645	108296668	3	+	27661255	K562	viability	GGCATGAATAAATCAAATATGGG	HHLA2	ENSG00000114455	-0.0011597032361805315	[1954,2054]	[1681,1527]	0	dCas9-KRAB	negative selection	5484590
108355190	108355213	3	+	27260156	BXPC3	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.33123303933761433	[575]	[695,574,752,1055]	7	hSpCas9	negative selection	5547409
108355360	108355383	3	+	27260156	BXPC3	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.21131006004934338	[143]	[104,116,142,161]	-5	hSpCas9	negative selection	5547410
108358006	108358029	3	+	27260156	BXPC3	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.2605265439998908	[534]	[734,553,652,741]	6	hSpCas9	negative selection	5547411
108358145	108358168	3	-	27260156	BXPC3	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	-0.004399105133864323	[1077]	[998,1048,1235,1236]	0	hSpCas9	negative selection	5611670
108351843	108351866	3	-	27260156	BXPC3	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.2121004711495571	[25]	[16,24,63,20]	5	hSpCas9	negative selection	5611671
108351847	108351870	3	+	27260156	BXPC3	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.61549562815819	[377]	[235,287,276,225]	-8	hSpCas9	negative selection	5611672
108355190	108355213	3	+	27260156	A673	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.3353260106497317	[575]	[974,643,1000,885]	7	hSpCas9	negative selection	5668660
108355360	108355383	3	+	27260156	A673	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.06361784050004515	[143]	[181,137,168,237]	1	hSpCas9	negative selection	5668661
108358006	108358029	3	+	27260156	A673	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.42725643063094504	[534]	[905,851,864,833]	8	hSpCas9	negative selection	5668662
108358145	108358168	3	-	27260156	A673	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.10124409809813018	[1077]	[1441,1312,1255,1558]	2	hSpCas9	negative selection	5732921
108351843	108351866	3	-	27260156	A673	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-1.1672601448994495	[25]	[16,7,17,12]	-9	hSpCas9	negative selection	5732922
108351847	108351870	3	+	27260156	A673	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.1521186090254283	[377]	[476,425,302,436]	-4	hSpCas9	negative selection	5732923
108355190	108355213	3	+	27260156	A375	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.795232371785235	[575]	[1053,1349,952,1314]	9	hSpCas9	negative selection	5789911
108355360	108355383	3	+	27260156	A375	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.02418707427607858	[143]	[158,83,189,230]	0	hSpCas9	negative selection	5789912
108358006	108358029	3	+	27260156	A375	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.19460135070959733	[534]	[750,537,844,700]	3	hSpCas9	negative selection	5789913
108358145	108358168	3	-	27260156	A375	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.21652974086272647	[1077]	[1691,1559,1299,1325]	3	hSpCas9	negative selection	5854172
108351843	108351866	3	-	27260156	A375	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.6559109010199795	[25]	[53,38,48,47]	8	hSpCas9	negative selection	5854173
108351847	108351870	3	+	27260156	A375	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.5937934588690359	[377]	[287,228,219,408]	-7	hSpCas9	negative selection	5854174
108355190	108355213	3	+	27260156	COLO741	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4969408428967517	[575]	[1047,884,1170]	8	hSpCas9	negative selection	5911162
108355360	108355383	3	+	27260156	COLO741	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.0069753815601691915	[143]	[171,193,186]	0	hSpCas9	negative selection	5911163
108358006	108358029	3	+	27260156	COLO741	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.1804178169127278	[534]	[1080,679,599]	4	hSpCas9	negative selection	5911164
108358145	108358168	3	-	27260156	COLO741	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.04037718775667942	[1077]	[1753,1115,1404]	0	hSpCas9	negative selection	5975423
108351843	108351866	3	-	27260156	COLO741	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.21990069265980594	[25]	[6,51,24]	-5	hSpCas9	negative selection	5975424
108351847	108351870	3	+	27260156	COLO741	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.16389962507620462	[377]	[522,562,534]	3	hSpCas9	negative selection	5975425
108355190	108355213	3	+	27260156	CAL120	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4241909808574876	[575]	[968,954,961]	6	hSpCas9	negative selection	6032413
108355360	108355383	3	+	27260156	CAL120	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.6277921782654416	[143]	[230,223,366]	8	hSpCas9	negative selection	6032414
108358006	108358029	3	+	27260156	CAL120	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.5677062934488408	[534]	[1506,761,772]	8	hSpCas9	negative selection	6032415
108358145	108358168	3	-	27260156	CAL120	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.3265227487356679	[1077]	[2078,1316,1708]	5	hSpCas9	negative selection	6096674
108351843	108351866	3	-	27260156	CAL120	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	1.3906234917281988	[25]	[33,26,183]	9	hSpCas9	negative selection	6096675
108351847	108351870	3	+	27260156	CAL120	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.31329885853972056	[377]	[726,708,342]	5	hSpCas9	negative selection	6096676
108355190	108355213	3	+	27260156	CADOES1	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4989204248079869	[575]	[671,719,733,907]	7	hSpCas9	negative selection	6153664
108355360	108355383	3	+	27260156	CADOES1	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.21479387891954227	[143]	[163,196,150,107]	3	hSpCas9	negative selection	6153665
108358006	108358029	3	+	27260156	CADOES1	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.2902090760105747	[534]	[632,561,620,617]	5	hSpCas9	negative selection	6153666
108358145	108358168	3	-	27260156	CADOES1	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.17747463603544533	[1077]	[1306,949,1106,1171]	3	hSpCas9	negative selection	6217925
108351843	108351866	3	-	27260156	CADOES1	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.6424386916609168	[25]	[14,65,34,34]	9	hSpCas9	negative selection	6217926
108351847	108351870	3	+	27260156	CADOES1	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.24630725695800199	[377]	[391,237,237,317]	-4	hSpCas9	negative selection	6217927
108355190	108355213	3	+	27260156	EWS502	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.6510608770953976	[575]	[1018,909,913,980]	9	hSpCas9	negative selection	6274915
108355360	108355383	3	+	27260156	EWS502	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.37412255998775557	[143]	[152,400,141,81]	6	hSpCas9	negative selection	6274916
108358006	108358029	3	+	27260156	EWS502	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.2726438550298208	[534]	[651,744,663,674]	5	hSpCas9	negative selection	6274917
108358145	108358168	3	-	27260156	EWS502	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	-0.009943081240119334	[1077]	[973,1226,1198,1148]	0	hSpCas9	negative selection	6339176
108351843	108351866	3	-	27260156	EWS502	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-1.0068121801504804	[25]	[0,2,40,11]	-8	hSpCas9	negative selection	6339177
108351847	108351870	3	+	27260156	EWS502	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.19980974628718234	[377]	[264,459,344,326]	-4	hSpCas9	negative selection	6339178
108355190	108355213	3	+	27260156	EW8	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.44300235325683196	[575]	[706,667,615,556]	7	hSpCas9	negative selection	6396166
108355360	108355383	3	+	27260156	EW8	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.13644315046680822	[143]	[102,36,138,138]	-3	hSpCas9	negative selection	6396167
108358006	108358029	3	+	27260156	EW8	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.30693370451153995	[534]	[604,468,500,581]	5	hSpCas9	negative selection	6396168
108358145	108358168	3	-	27260156	EW8	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.07540809434836993	[1077]	[1064,933,828,882]	1	hSpCas9	negative selection	6460427
108351843	108351866	3	-	27260156	EW8	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	1.356920492511053	[25]	[45,98,30,42]	9	hSpCas9	negative selection	6460428
108351847	108351870	3	+	27260156	EW8	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.41131471536010045	[377]	[312,324,281,717]	7	hSpCas9	negative selection	6460429
108355190	108355213	3	+	27260156	CORL105	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.21558561857888708	[575]	[739,604,927,882]	4	hSpCas9	negative selection	6517417
108355360	108355383	3	+	27260156	CORL105	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.010124893852800021	[143]	[135,139,224,185]	0	hSpCas9	negative selection	6517418
108358006	108358029	3	+	27260156	CORL105	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.2811770641401107	[534]	[726,765,812,744]	5	hSpCas9	negative selection	6517419
108358145	108358168	3	-	27260156	CORL105	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.26147813496364036	[1077]	[1534,1501,1671,1367]	5	hSpCas9	negative selection	6581678
108351843	108351866	3	-	27260156	CORL105	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.366883145528869	[25]	[16,47,57,35]	6	hSpCas9	negative selection	6581679
108351847	108351870	3	+	27260156	CORL105	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.6050346133942635	[377]	[301,212,357,302]	-8	hSpCas9	negative selection	6581680
108355190	108355213	3	+	27260156	HS294T	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.6509028413564932	[575]	[266,282,517,337]	8	hSpCas9	negative selection	6638668
108355360	108355383	3	+	27260156	HS294T	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.0172520434819059	[143]	[105,35,42,31]	0	hSpCas9	negative selection	6638669
108358006	108358029	3	+	27260156	HS294T	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.07205368657674788	[534]	[159,176,286,258]	1	hSpCas9	negative selection	6638670
108358145	108358168	3	-	27260156	HS294T	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	-0.34174279582485323	[1077]	[252,306,361,414]	-5	hSpCas9	negative selection	6702929
108351843	108351866	3	-	27260156	HS294T	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	1.5911029310171907	[25]	[6,13,76,24]	9	hSpCas9	negative selection	6702930
108351847	108351870	3	+	27260156	HS294T	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.21613601337583221	[377]	[110,105,306,160]	3	hSpCas9	negative selection	6702931
108355190	108355213	3	+	27260156	HCC44	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5941934730244733	[575]	[1213,783,1264,767]	8	hSpCas9	negative selection	6759919
108355360	108355383	3	+	27260156	HCC44	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.20548066471698778	[143]	[79,151,224,114]	-3	hSpCas9	negative selection	6759920
108358006	108358029	3	+	27260156	HCC44	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.6135301632247756	[534]	[1092,663,1248,801]	8	hSpCas9	negative selection	6759921
108358145	108358168	3	-	27260156	HCC44	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.2857265887185201	[1077]	[1451,1341,1710,1483]	4	hSpCas9	negative selection	6824180
108351843	108351866	3	-	27260156	HCC44	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.3445312399397622	[25]	[55,31,42,21]	5	hSpCas9	negative selection	6824181
108351847	108351870	3	+	27260156	HCC44	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.2922598520561063	[377]	[640,421,679,402]	5	hSpCas9	negative selection	6824182
108355190	108355213	3	+	27260156	G402	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.8487207672961103	[575]	[1665,1127,1199,1120]	9	hSpCas9	negative selection	6881170
108355360	108355383	3	+	27260156	G402	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.8144855177447093	[143]	[169,186,738,120]	8	hSpCas9	negative selection	6881171
108358006	108358029	3	+	27260156	G402	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.32060306397334876	[534]	[1553,779,689,360]	4	hSpCas9	negative selection	6881172
108358145	108358168	3	-	27260156	G402	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.5143359191521579	[1077]	[2368,2281,1535,1436]	6	hSpCas9	negative selection	6945431
108351843	108351866	3	-	27260156	G402	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-1.6402504285427906	[25]	[0,22,3,11]	-9	hSpCas9	negative selection	6945432
108351847	108351870	3	+	27260156	G402	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.8734184236242513	[377]	[339,305,166,210]	-8	hSpCas9	negative selection	6945433
108355190	108355213	3	+	27260156	L33	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.10814683200264485	[575]	[687,281,333,573]	2	hSpCas9	negative selection	7002421
108355360	108355383	3	+	27260156	L33	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.5485959646498195	[143]	[98,43,66,80]	-8	hSpCas9	negative selection	7002422
108358006	108358029	3	+	27260156	L33	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.022834123160475894	[534]	[563,195,351,570]	0	hSpCas9	negative selection	7002423
108358145	108358168	3	-	27260156	L33	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.02047037211167435	[1077]	[1038,445,573,1330]	0	hSpCas9	negative selection	7066682
108351843	108351866	3	-	27260156	L33	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.23377877172274353	[25]	[10,11,22,11]	-5	hSpCas9	negative selection	7066683
108351847	108351870	3	+	27260156	L33	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.16237235624392948	[377]	[485,148,268,412]	3	hSpCas9	negative selection	7066684
108355190	108355213	3	+	27260156	K562	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.95199723118279	[575]	[1089,1111,916,861]	9	hSpCas9	negative selection	7123672
108355360	108355383	3	+	27260156	K562	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.45536802914330576	[143]	[18,255,301,120]	6	hSpCas9	negative selection	7123673
108358006	108358029	3	+	27260156	K562	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.3981085132819124	[534]	[581,683,669,569]	5	hSpCas9	negative selection	7123674
108358145	108358168	3	-	27260156	K562	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.38373581866705675	[1077]	[930,1293,1530,1211]	5	hSpCas9	negative selection	7187933
108351843	108351866	3	-	27260156	K562	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.8558261461662884	[25]	[0,3,7,33]	-7	hSpCas9	negative selection	7187934
108351847	108351870	3	+	27260156	K562	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-1.0281474373047172	[377]	[230,147,138,145]	-8	hSpCas9	negative selection	7187935
108355190	108355213	3	+	27260156	HT29	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5984237673599282	[575]	[1145,1128,1068,918]	9	hSpCas9	negative selection	7244923
108355360	108355383	3	+	27260156	HT29	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.38656700077299955	[143]	[87,142,167,132]	-6	hSpCas9	negative selection	7244924
108358006	108358029	3	+	27260156	HT29	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.3763634901625032	[534]	[859,824,623,1036]	7	hSpCas9	negative selection	7244925
108358145	108358168	3	-	27260156	HT29	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.18198102193546872	[1077]	[1492,1659,1338,1461]	3	hSpCas9	negative selection	7309184
108351843	108351866	3	-	27260156	HT29	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.6975699655538063	[25]	[102,12,25,61]	9	hSpCas9	negative selection	7309185
108351847	108351870	3	+	27260156	HT29	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.19632794934993175	[377]	[482,433,351,347]	-4	hSpCas9	negative selection	7309186
108355190	108355213	3	+	27260156	MHHES1	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5248630572384094	[575]	[1114,718,974,908]	8	hSpCas9	negative selection	7366174
108355360	108355383	3	+	27260156	MHHES1	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.615557182891673	[143]	[60,170,149,52]	-8	hSpCas9	negative selection	7366175
108358006	108358029	3	+	27260156	MHHES1	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.48245206269460444	[534]	[1005,958,840,624]	8	hSpCas9	negative selection	7366176
108358145	108358168	3	-	27260156	MHHES1	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.2201435903525213	[1077]	[1665,1461,1300,1264]	4	hSpCas9	negative selection	7430435
108351843	108351866	3	-	27260156	MHHES1	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.15466426055003968	[25]	[12,45,29,17]	-3	hSpCas9	negative selection	7430436
108351847	108351870	3	+	27260156	MHHES1	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.4298015954152868	[377]	[352,435,321,191]	-7	hSpCas9	negative selection	7430437
108355190	108355213	3	+	27260156	MEWO	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.34163347690870766	[575]	[812,613,646]	7	hSpCas9	negative selection	7487425
108355360	108355383	3	+	27260156	MEWO	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.38939667027763414	[143]	[89,111,103]	-7	hSpCas9	negative selection	7487426
108358006	108358029	3	+	27260156	MEWO	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.36093332697337405	[534]	[879,482,611]	7	hSpCas9	negative selection	7487427
108358145	108358168	3	-	27260156	MEWO	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.1116833647285096	[1077]	[1116,920,1236]	2	hSpCas9	negative selection	7551686
108351843	108351866	3	-	27260156	MEWO	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.4300717164204837	[25]	[30,25,40]	8	hSpCas9	negative selection	7551687
108351847	108351870	3	+	27260156	MEWO	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.24312361932197754	[377]	[471,402,390]	5	hSpCas9	negative selection	7551688
108355190	108355213	3	+	27260156	LNCAPCLONEFGC	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.3696973623069975	[575]	[784,642,679,588]	6	hSpCas9	negative selection	7608676
108355360	108355383	3	+	27260156	LNCAPCLONEFGC	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.16735048716582113	[143]	[83,118,122,139]	-3	hSpCas9	negative selection	7608677
108358006	108358029	3	+	27260156	LNCAPCLONEFGC	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.4103283661426918	[534]	[725,611,526,693]	6	hSpCas9	negative selection	7608678
108358145	108358168	3	-	27260156	LNCAPCLONEFGC	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.39896822848154834	[1077]	[1236,1008,1577,1387]	6	hSpCas9	negative selection	7672937
108351843	108351866	3	-	27260156	LNCAPCLONEFGC	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.10594710233849103	[25]	[3,31,33,18]	-2	hSpCas9	negative selection	7672938
108351847	108351870	3	+	27260156	LNCAPCLONEFGC	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.3868880876760929	[377]	[373,218,214,232]	-6	hSpCas9	negative selection	7672939
108355190	108355213	3	+	27260156	PANC0327	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4158264451717448	[575]	[690,528,861,668]	6	hSpCas9	negative selection	7729927
108355360	108355383	3	+	27260156	PANC0327	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.11090330584460384	[143]	[201,150,81,120]	1	hSpCas9	negative selection	7729928
108358006	108358029	3	+	27260156	PANC0327	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.4348594774328129	[534]	[566,346,559,1126]	6	hSpCas9	negative selection	7729929
108358145	108358168	3	-	27260156	PANC0327	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.06470778940550925	[1077]	[1780,803,774,734]	0	hSpCas9	negative selection	7794188
108351843	108351866	3	-	27260156	PANC0327	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	1.9836356378722817	[25]	[24,73,54,207]	9	hSpCas9	negative selection	7794189
108351847	108351870	3	+	27260156	PANC0327	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.3752233446568566	[377]	[523,306,538,395]	5	hSpCas9	negative selection	7794190
108355190	108355213	3	+	27260156	NCIH2009	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5964133970280359	[575]	[1100,904,1624]	7	hSpCas9	negative selection	7851178
108355360	108355383	3	+	27260156	NCIH2009	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.7607535584265668	[143]	[154,128,78]	-7	hSpCas9	negative selection	7851179
108358006	108358029	3	+	27260156	NCIH2009	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.23096222740668493	[534]	[816,731,1071]	3	hSpCas9	negative selection	7851180
108358145	108358168	3	-	27260156	NCIH2009	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.23351589885687818	[1077]	[1908,1582,1847]	3	hSpCas9	negative selection	7915439
108351843	108351866	3	-	27260156	NCIH2009	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	1.3775265414337148	[25]	[43,40,188]	9	hSpCas9	negative selection	7915440
108351847	108351870	3	+	27260156	NCIH2009	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.04515592306229266	[377]	[643,445,471]	0	hSpCas9	negative selection	7915441
108355190	108355213	3	+	27260156	NCIH1373	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.0598168430346462	[575]	[2062,1223,1146,276]	9	hSpCas9	negative selection	7972429
108355360	108355383	3	+	27260156	NCIH1373	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-1.5693432133599028	[143]	[68,70,52,5]	-9	hSpCas9	negative selection	7972430
108358006	108358029	3	+	27260156	NCIH1373	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	-0.43584681159986377	[534]	[677,240,394,136]	-4	hSpCas9	negative selection	7972431
108358145	108358168	3	-	27260156	NCIH1373	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	-0.060102273618008795	[1077]	[1385,1021,1353,235]	0	hSpCas9	negative selection	8036690
108351843	108351866	3	-	27260156	NCIH1373	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.6794855824976667	[25]	[2,24,4,9]	-6	hSpCas9	negative selection	8036691
108351847	108351870	3	+	27260156	NCIH1373	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-1.5118769715618028	[377]	[119,195,77,50]	-9	hSpCas9	negative selection	8036692
108355190	108355213	3	+	27260156	PATU8902	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.058818493208806444	[575]	[559,957,946,846]	0	hSpCas9	negative selection	8093680
108355360	108355383	3	+	27260156	PATU8902	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.057518386717576586	[143]	[213,147,277,94]	0	hSpCas9	negative selection	8093681
108358006	108358029	3	+	27260156	PATU8902	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.16912403383599972	[534]	[862,775,813,904]	1	hSpCas9	negative selection	8093682
108358145	108358168	3	-	27260156	PATU8902	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.4080265990493679	[1077]	[1570,2417,1224,3073]	4	hSpCas9	negative selection	8157941
108351843	108351866	3	-	27260156	PATU8902	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.12015401759689492	[25]	[4,136,2,19]	1	hSpCas9	negative selection	8157942
108351847	108351870	3	+	27260156	PATU8902	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.27941859929332696	[377]	[523,687,184,393]	-3	hSpCas9	negative selection	8157943
108355190	108355213	3	+	27260156	PANC1	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.25042410975111734	[575]	[503,858,670,399]	4	hSpCas9	negative selection	8214931
108355360	108355383	3	+	27260156	PANC1	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.4797730184628184	[143]	[75,144,42,98]	-6	hSpCas9	negative selection	8214932
108358006	108358029	3	+	27260156	PANC1	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.24768425229865265	[534]	[666,611,380,525]	4	hSpCas9	negative selection	8214933
108358145	108358168	3	-	27260156	PANC1	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.13579223508723404	[1077]	[953,1510,960,769]	2	hSpCas9	negative selection	8279192
108351843	108351866	3	-	27260156	PANC1	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.25108011418323617	[25]	[27,36,6,7]	-4	hSpCas9	negative selection	8279193
108351847	108351870	3	+	27260156	PANC1	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.17332832019383954	[377]	[217,490,183,294]	-3	hSpCas9	negative selection	8279194
108355190	108355213	3	+	27260156	PANC0813	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.30098301807863365	[575]	[1005,715,987,649]	5	hSpCas9	negative selection	8336182
108355360	108355383	3	+	27260156	PANC0813	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.2527160951949887	[143]	[120,268,82,94]	-4	hSpCas9	negative selection	8336183
108358006	108358029	3	+	27260156	PANC0813	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.3387670962797484	[534]	[849,945,903,499]	5	hSpCas9	negative selection	8336184
108358145	108358168	3	-	27260156	PANC0813	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.18919355187813203	[1077]	[1631,1493,1395,1276]	3	hSpCas9	negative selection	8400443
108351843	108351866	3	-	27260156	PANC0813	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.8270933747252358	[25]	[108,48,17,45]	9	hSpCas9	negative selection	8400444
108351847	108351870	3	+	27260156	PANC0813	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.013599585855207541	[377]	[531,421,563,259]	0	hSpCas9	negative selection	8400445
108355190	108355213	3	+	27260156	RDES	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4671322784045044	[575]	[787,844,896,1177]	7	hSpCas9	negative selection	8457433
108355360	108355383	3	+	27260156	RDES	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.3367681160721887	[143]	[198,146,197,308]	5	hSpCas9	negative selection	8457434
108358006	108358029	3	+	27260156	RDES	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.3761808340714626	[534]	[580,801,833,1038]	6	hSpCas9	negative selection	8457435
108358145	108358168	3	-	27260156	RDES	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.15104281798816244	[1077]	[1214,1314,1571,1413]	2	hSpCas9	negative selection	8521694
108351843	108351866	3	-	27260156	RDES	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.06338511109707756	[25]	[33,8,33,38]	-1	hSpCas9	negative selection	8521695
108351847	108351870	3	+	27260156	RDES	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.3671046697652676	[377]	[281,294,442,337]	-6	hSpCas9	negative selection	8521696
108355190	108355213	3	+	27260156	PC3	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.3534999426546475	[575]	[434,737,1269,763]	7	hSpCas9	negative selection	8578684
108355360	108355383	3	+	27260156	PC3	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.3455121769638303	[143]	[53,163,193,83]	-7	hSpCas9	negative selection	8578685
108358006	108358029	3	+	27260156	PC3	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.4999473081305736	[534]	[523,660,1362,730]	8	hSpCas9	negative selection	8578686
108358145	108358168	3	-	27260156	PC3	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.07281819558873481	[1077]	[682,1109,2086,1102]	1	hSpCas9	negative selection	8642945
108351843	108351866	3	-	27260156	PC3	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.9061500494908481	[25]	[0,12,36,18]	-9	hSpCas9	negative selection	8642946
108351847	108351870	3	+	27260156	PC3	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.41236505167711646	[377]	[455,357,769,485]	8	hSpCas9	negative selection	8642947
108355190	108355213	3	+	27260156	PATU8988T	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.2897322936922833	[575]	[704,631,714,662]	5	hSpCas9	negative selection	8699935
108355360	108355383	3	+	27260156	PATU8988T	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.3948622315668491	[143]	[229,163,137,199]	6	hSpCas9	negative selection	8699936
108358006	108358029	3	+	27260156	PATU8988T	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.2935423797814893	[534]	[472,614,829,609]	5	hSpCas9	negative selection	8699937
108358145	108358168	3	-	27260156	PATU8988T	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.3094527141983785	[1077]	[1282,1113,1616,1113]	5	hSpCas9	negative selection	8764196
108351843	108351866	3	-	27260156	PATU8988T	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-2.678962492744361	[25]	[3,4,0,5]	-9	hSpCas9	negative selection	8764197
108351847	108351870	3	+	27260156	PATU8988T	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.3099577713849275	[377]	[498,460,366,488]	5	hSpCas9	negative selection	8764198
108355190	108355213	3	+	27260156	T47D	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5471157249483356	[575]	[911,929,995,1090]	9	hSpCas9	negative selection	8821186
108355360	108355383	3	+	27260156	T47D	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.02306880698588487	[143]	[134,171,171,180]	0	hSpCas9	negative selection	8821187
108358006	108358029	3	+	27260156	T47D	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.39916602591265476	[534]	[711,800,824,954]	8	hSpCas9	negative selection	8821188
108358145	108358168	3	-	27260156	T47D	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.18426387447815995	[1077]	[1409,1284,1451,1576]	4	hSpCas9	negative selection	8885447
108351843	108351866	3	-	27260156	T47D	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.7152279047720183	[25]	[31,58,54,51]	9	hSpCas9	negative selection	8885448
108351847	108351870	3	+	27260156	T47D	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.10921664634798148	[377]	[562,395,454,493]	2	hSpCas9	negative selection	8885449
108355190	108355213	3	+	27260156	SU8686	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.11045651315584593	[575]	[563,602,476,860]	1	hSpCas9	negative selection	8942437
108355360	108355383	3	+	27260156	SU8686	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.5653240301991465	[143]	[52,115,62,165]	-7	hSpCas9	negative selection	8942438
108358006	108358029	3	+	27260156	SU8686	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	-0.2113163467418527	[534]	[444,411,488,497]	-4	hSpCas9	negative selection	8942439
108358145	108358168	3	-	27260156	SU8686	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.12773701278307859	[1077]	[1031,1050,1161,1501]	2	hSpCas9	negative selection	9006698
108351843	108351866	3	-	27260156	SU8686	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.3166500119538136	[25]	[16,24,66,20]	5	hSpCas9	negative selection	9006699
108351847	108351870	3	+	27260156	SU8686	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.5279485422844059	[377]	[226,212,269,352]	-7	hSpCas9	negative selection	9006700
108355190	108355213	3	+	27260156	SKES1	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.5885031509704071	[575]	[747,1063,895,758]	9	hSpCas9	negative selection	9063688
108355360	108355383	3	+	27260156	SKES1	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.1242526298908655	[143]	[137,166,117,195]	2	hSpCas9	negative selection	9063689
108358006	108358029	3	+	27260156	SKES1	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.45437703712486316	[534]	[1023,642,721,576]	8	hSpCas9	negative selection	9063690
108358145	108358168	3	-	27260156	SKES1	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	-0.008100465435075366	[1077]	[1168,1176,1012,948]	0	hSpCas9	negative selection	9127949
108351843	108351866	3	-	27260156	SKES1	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.16264199504156185	[25]	[24,6,18,37]	-4	hSpCas9	negative selection	9127950
108351847	108351870	3	+	27260156	SKES1	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.04087562904340081	[377]	[307,471,430,266]	-1	hSpCas9	negative selection	9127951
108355190	108355213	3	+	27260156	TOV112D	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.48256408646794896	[575]	[691,896,1179,475]	8	hSpCas9	negative selection	9184939
108355360	108355383	3	+	27260156	TOV112D	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.14042092955630414	[143]	[92,275,138,49]	-3	hSpCas9	negative selection	9184940
108358006	108358029	3	+	27260156	TOV112D	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.5688269895814018	[534]	[593,1046,748,831]	8	hSpCas9	negative selection	9184941
108358145	108358168	3	-	27260156	TOV112D	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	-0.015472437694918462	[1077]	[1152,1402,1156,658]	0	hSpCas9	negative selection	9249200
108351843	108351866	3	-	27260156	TOV112D	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	1.1331533087888346	[25]	[0,137,99,5]	9	hSpCas9	negative selection	9249201
108351847	108351870	3	+	27260156	TOV112D	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.04097870432464312	[377]	[430,391,332,404]	0	hSpCas9	negative selection	9249202
108355190	108355213	3	+	27260156	TC71	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.3971533182326841	[575]	[789,757,723,994]	8	hSpCas9	negative selection	9306190
108355360	108355383	3	+	27260156	TC71	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	-0.27449692335342224	[143]	[87,109,138,176]	-6	hSpCas9	negative selection	9306191
108358006	108358029	3	+	27260156	TC71	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.23463573033947255	[534]	[545,735,669,754]	6	hSpCas9	negative selection	9306192
108358145	108358168	3	-	27260156	TC71	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.1257474584216236	[1077]	[1265,1068,1321,1391]	3	hSpCas9	negative selection	9370451
108351843	108351866	3	-	27260156	TC71	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	-0.14934188451417008	[25]	[21,38,23,14]	-4	hSpCas9	negative selection	9370452
108351847	108351870	3	+	27260156	TC71	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	0.058387600433805587	[377]	[407,451,321,514]	1	hSpCas9	negative selection	9370453
108355190	108355213	3	+	27260156	TC32	viability	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.33290874904614526	[575]	[667,526,785,788]	6	hSpCas9	negative selection	9427441
108355360	108355383	3	+	27260156	TC32	viability	ACAGGGCGCTGGACGATGAAAGG	HHLA2	ENSG00000114455	0.07744364377983137	[143]	[98,96,242,165]	1	hSpCas9	negative selection	9427442
108358006	108358029	3	+	27260156	TC32	viability	TCAATGAATCCCGATTCTCATGG	HHLA2	ENSG00000114455	0.6296284832558208	[534]	[569,751,800,991]	9	hSpCas9	negative selection	9427443
108358145	108358168	3	-	27260156	TC32	viability	ACTTACCTACATGCACTGTGTGG	HHLA2	ENSG00000114455	0.2903399309729031	[1077]	[1197,926,1670,1285]	5	hSpCas9	negative selection	9491702
108351843	108351866	3	-	27260156	TC32	viability	TCAGAGATGTTATGAGAATGAGG	HHLA2	ENSG00000114455	0.3551004624212255	[25]	[12,14,42,64]	6	hSpCas9	negative selection	9491703
108351847	108351870	3	+	27260156	TC32	viability	ATTCTCATAACATCTCTGAGTGG	HHLA2	ENSG00000114455	-0.6357885401410688	[377]	[155,125,304,385]	-8	hSpCas9	negative selection	9491704
108353529	108353552	3	+	27869803	HPAFII	viability after 27 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	1.3964031911482233	[142]	[354,66,NaN]	9	hSpCas9	negative selection	9581741
108353599	108353622	3	-	27869803	HPAFII	viability after 27 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.9785941229454878	[244]	[219,281,NaN]	7	hSpCas9	negative selection	9581742
108353690	108353713	3	+	27869803	HPAFII	viability after 27 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.9204430343299573	[349]	[272,410,NaN]	7	hSpCas9	negative selection	9581743
108355190	108355213	3	+	27869803	HPAFII	viability after 27 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.6482530031711065	[101]	[274,78,NaN]	9	hSpCas9	negative selection	9581744
108355342	108355365	3	+	27869803	HPAFII	viability after 27 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.33433979554621307	[428]	[357,222,NaN]	2	hSpCas9	negative selection	9581745
108376526	108376549	3	-	27869803	HPAFII	viability after 27 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	1.7853818422772871	[276]	[819,236,NaN]	9	hSpCas9	negative selection	9581746
108353529	108353552	3	+	27869803	HPAFII	viability after 15 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	1.045964124708202	[142]	[386,273,NaN]	9	hSpCas9	negative selection	9664190
108353599	108353622	3	-	27869803	HPAFII	viability after 15 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.6846125045526706	[244]	[511,367,NaN]	7	hSpCas9	negative selection	9664191
108353690	108353713	3	+	27869803	HPAFII	viability after 15 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.6029157547989447	[349]	[730,471,NaN]	7	hSpCas9	negative selection	9664192
108355190	108355213	3	+	27869803	HPAFII	viability after 15 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.0652841765037548	[101]	[340,159,NaN]	9	hSpCas9	negative selection	9664193
108355342	108355365	3	+	27869803	HPAFII	viability after 15 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.4223207847517638	[428]	[1038,355,NaN]	5	hSpCas9	negative selection	9664194
108376526	108376549	3	-	27869803	HPAFII	viability after 15 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	1.2885052589392036	[276]	[971,574,NaN]	9	hSpCas9	negative selection	9664195
108353529	108353552	3	+	27869803	ASPC1	viability after 36 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.04524132638896369	[516]	[123,73,316]	0	hSpCas9	negative selection	9746639
108353599	108353622	3	-	27869803	ASPC1	viability after 36 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.16334776776857118	[751]	[400,362,160]	1	hSpCas9	negative selection	9746640
108353690	108353713	3	+	27869803	ASPC1	viability after 36 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.032625981213119326	[941]	[270,476,266]	0	hSpCas9	negative selection	9746641
108355190	108355213	3	+	27869803	ASPC1	viability after 36 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.4247016266310064	[327]	[263,180,52]	4	hSpCas9	negative selection	9746642
108355342	108355365	3	+	27869803	ASPC1	viability after 36 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.42623656447604596	[914]	[1190,106,145]	4	hSpCas9	negative selection	9746643
108376526	108376549	3	-	27869803	ASPC1	viability after 36 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.02737764234380019	[691]	[274,188,245]	0	hSpCas9	negative selection	9746644
108353529	108353552	3	+	27869803	PATU8988S	viability after 35 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.44396121070014327	[438]	[247,232,NaN]	5	hSpCas9	negative selection	9829088
108353599	108353622	3	-	27869803	PATU8988S	viability after 35 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.33583180113635647	[588]	[253,344,NaN]	4	hSpCas9	negative selection	9829089
108353690	108353713	3	+	27869803	PATU8988S	viability after 35 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.2767775653701079	[939]	[310,313,NaN]	-3	hSpCas9	negative selection	9829090
108355190	108355213	3	+	27869803	PATU8988S	viability after 35 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.3745541054847774	[381]	[180,217,NaN]	4	hSpCas9	negative selection	9829091
108355342	108355365	3	+	27869803	PATU8988S	viability after 35 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	-0.1276143408225885	[971]	[284,431,NaN]	-1	hSpCas9	negative selection	9829092
108376526	108376549	3	-	27869803	PATU8988S	viability after 35 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.035983011406855	[687]	[167,372,NaN]	0	hSpCas9	negative selection	9829093
108353529	108353552	3	+	27869803	PATU8988S	viability after 31 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	0.3183890316492656	[438]	[190,252,NaN]	4	hSpCas9	negative selection	9911537
108353599	108353622	3	-	27869803	PATU8988S	viability after 31 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	0.26976435417051775	[588]	[232,346,NaN]	3	hSpCas9	negative selection	9911538
108353690	108353713	3	+	27869803	PATU8988S	viability after 31 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.4185485539760676	[939]	[235,336,NaN]	-5	hSpCas9	negative selection	9911539
108355190	108355213	3	+	27869803	PATU8988S	viability after 31 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	0.1732284614778556	[381]	[136,215,NaN]	2	hSpCas9	negative selection	9911540
108355342	108355365	3	+	27869803	PATU8988S	viability after 31 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.2406941814369975	[971]	[398,532,NaN]	3	hSpCas9	negative selection	9911541
108376526	108376549	3	-	27869803	PATU8988S	viability after 31 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	-0.1833561248939752	[687]	[212,277,NaN]	-2	hSpCas9	negative selection	9911542
108353529	108353552	3	+	27869803	HPAFII	viability after 35 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	1.741033325847604	[142]	[344,125,NaN]	9	hSpCas9	negative selection	9993986
108353599	108353622	3	-	27869803	HPAFII	viability after 35 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	1.489475185233164	[244]	[280,423,NaN]	8	hSpCas9	negative selection	9993987
108353690	108353713	3	+	27869803	HPAFII	viability after 35 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.8141396917120202	[349]	[208,426,NaN]	5	hSpCas9	negative selection	9993988
108355190	108355213	3	+	27869803	HPAFII	viability after 35 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.647152904055706	[101]	[220,94,NaN]	9	hSpCas9	negative selection	9993989
108355342	108355365	3	+	27869803	HPAFII	viability after 35 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.3347039586455953	[428]	[287,257,NaN]	2	hSpCas9	negative selection	9993990
108376526	108376549	3	-	27869803	HPAFII	viability after 35 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	1.7872567503279173	[276]	[634,313,NaN]	9	hSpCas9	negative selection	9993991
108353529	108353552	3	+	27869803	HPAFII	viability after 31 days	GATCCGAAGTCGTAATACACTGG	HHLA2	ENSG00000114455	1.8328306282428835	[142]	[450,105,NaN]	9	hSpCas9	negative selection	10076435
108353599	108353622	3	-	27869803	HPAFII	viability after 31 days	TGGGATCTTGGCTTTCCAAATGG	HHLA2	ENSG00000114455	1.3800308181645338	[244]	[220,506,NaN]	8	hSpCas9	negative selection	10076436
108353690	108353713	3	+	27869803	HPAFII	viability after 31 days	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	1.0784073283423106	[349]	[264,577,NaN]	7	hSpCas9	negative selection	10076437
108355190	108355213	3	+	27869803	HPAFII	viability after 31 days	ATCCTCGTCCAATTATCACGTGG	HHLA2	ENSG00000114455	1.4845475382454116	[101]	[208,106,NaN]	9	hSpCas9	negative selection	10076438
108355342	108355365	3	+	27869803	HPAFII	viability after 31 days	CTGCTGAAGCAAACATGGACAGG	HHLA2	ENSG00000114455	0.29460980459551434	[428]	[357,226,NaN]	2	hSpCas9	negative selection	10076439
108376526	108376549	3	-	27869803	HPAFII	viability after 31 days	TTCGCCATTATCGGGTGCACTGG	HHLA2	ENSG00000114455	1.8263789000936144	[276]	[792,287,NaN]	9	hSpCas9	negative selection	10076440
108362353	108362376	3	+	28162770	P31FUJ	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.3294402198066939	[383]	[566]	3	hSpCas9	negative selection	10168736
108357933	108357956	3	+	28162770	P31FUJ	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.20396881681174667	[279]	[378]	2	hSpCas9	negative selection	10168737
108362393	108362416	3	-	28162770	P31FUJ	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.2578329137586244	[78]	[110]	2	hSpCas9	negative selection	10168738
108353755	108353778	3	+	28162770	P31FUJ	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.26969813611480464	[167]	[237]	3	hSpCas9	negative selection	10168739
108376506	108376529	3	-	28162770	P31FUJ	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.4405161707276245	[189]	[302]	5	hSpCas9	negative selection	10168740
108353690	108353713	3	+	28162770	P31FUJ	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.018736562581585847	[314]	[374]	0	hSpCas9	negative selection	10168741
108355349	108355372	3	+	28162770	P31FUJ	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	0.7306719195605074	[39]	[77]	8	hSpCas9	negative selection	10168742
108362425	108362448	3	+	28162770	P31FUJ	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.5756785039203199	[365]	[640]	6	hSpCas9	negative selection	10168743
108375747	108375770	3	+	28162770	P31FUJ	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	0.1233416058108967	[49]	[63]	1	hSpCas9	negative selection	10168744
108355192	108355215	3	-	28162770	P31FUJ	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.9214445831701326	[256]	[571]	9	hSpCas9	negative selection	10168745
108362353	108362376	3	+	28162770	TF1	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	NaN	[NaN]	[450]	1	hSpCas9	negative selection	10338102
108357933	108357956	3	+	28162770	TF1	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	NaN	[NaN]	[553]	1	hSpCas9	negative selection	10338103
108362393	108362416	3	-	28162770	TF1	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10338104
108353755	108353778	3	+	28162770	TF1	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10338105
108376506	108376529	3	-	28162770	TF1	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	NaN	[NaN]	[270]	1	hSpCas9	negative selection	10338106
108353690	108353713	3	+	28162770	TF1	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	NaN	[NaN]	[316]	1	hSpCas9	negative selection	10338107
108355349	108355372	3	+	28162770	TF1	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10338108
108362425	108362448	3	+	28162770	TF1	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	NaN	[NaN]	[319]	1	hSpCas9	negative selection	10338109
108375747	108375770	3	+	28162770	TF1	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10338110
108355192	108355215	3	-	28162770	TF1	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	NaN	[NaN]	[261]	1	hSpCas9	negative selection	10338111
108362353	108362376	3	+	28162770	SKM1	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.6760251659278698	[113]	[321]	6	hSpCas9	negative selection	10507468
108357933	108357956	3	+	28162770	SKM1	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.3268616878924771	[68]	[152]	3	hSpCas9	negative selection	10507469
108362393	108362416	3	-	28162770	SKM1	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.14147242595288034	[19]	[38]	1	hSpCas9	negative selection	10507470
108353755	108353778	3	+	28162770	SKM1	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	-0.17249894510613875	[50]	[79]	-1	hSpCas9	negative selection	10507471
108376506	108376529	3	-	28162770	SKM1	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.38950240717170626	[56]	[131]	4	hSpCas9	negative selection	10507472
108353690	108353713	3	+	28162770	SKM1	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.310753510829766	[82]	[181]	3	hSpCas9	negative selection	10507473
108355349	108355372	3	+	28162770	SKM1	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	1.2136222117087156	[9]	[40]	9	hSpCas9	negative selection	10507474
108362425	108362448	3	+	28162770	SKM1	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.3935436829808401	[106]	[143]	-3	hSpCas9	negative selection	10507475
108375747	108375770	3	+	28162770	SKM1	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-1.7288922936305238	[14]	[7]	-8	hSpCas9	negative selection	10507476
108355192	108355215	3	-	28162770	SKM1	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.011537155839253577	[77]	[138]	0	hSpCas9	negative selection	10507477
108362353	108362376	3	+	28162770	SKM1	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.6760251659278698	[113]	[321]	6	hSpCas9	negative selection	10676834
108357933	108357956	3	+	28162770	SKM1	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.3268616878924771	[68]	[152]	3	hSpCas9	negative selection	10676835
108362393	108362416	3	-	28162770	SKM1	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.14147242595288034	[19]	[38]	1	hSpCas9	negative selection	10676836
108353755	108353778	3	+	28162770	SKM1	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	-0.17249894510613875	[50]	[79]	-1	hSpCas9	negative selection	10676837
108376506	108376529	3	-	28162770	SKM1	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.38950240717170626	[56]	[131]	4	hSpCas9	negative selection	10676838
108353690	108353713	3	+	28162770	SKM1	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.310753510829766	[82]	[181]	3	hSpCas9	negative selection	10676839
108355349	108355372	3	+	28162770	SKM1	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	1.2136222117087156	[9]	[40]	9	hSpCas9	negative selection	10676840
108362425	108362448	3	+	28162770	SKM1	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.3935436829808401	[106]	[143]	-3	hSpCas9	negative selection	10676841
108375747	108375770	3	+	28162770	SKM1	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-1.7288922936305238	[14]	[7]	-8	hSpCas9	negative selection	10676842
108355192	108355215	3	-	28162770	SKM1	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.011537155839253577	[77]	[138]	0	hSpCas9	negative selection	10676843
108362353	108362376	3	+	28162770	PL21	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	-0.9849717907676682	[381]	[83]	-6	hSpCas9	negative selection	10846200
108357933	108357956	3	+	28162770	PL21	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.9988814062422162	[191]	[166]	8	hSpCas9	negative selection	10846201
108362393	108362416	3	-	28162770	PL21	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.5411765323243871	[119]	[75]	5	hSpCas9	negative selection	10846202
108353755	108353778	3	+	28162770	PL21	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.833154244616618	[186]	[144]	7	hSpCas9	negative selection	10846203
108376506	108376529	3	-	28162770	PL21	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	-0.5754288189006334	[201]	[58]	-4	hSpCas9	negative selection	10846204
108353690	108353713	3	+	28162770	PL21	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.45526882223776766	[304]	[181]	4	hSpCas9	negative selection	10846205
108355349	108355372	3	+	28162770	PL21	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	-0.6411626394916214	[42]	[11]	-4	hSpCas9	negative selection	10846206
108362425	108362448	3	+	28162770	PL21	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.07996830470341498	[288]	[118]	0	hSpCas9	negative selection	10846207
108375747	108375770	3	+	28162770	PL21	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-2.8873232267610196	[33]	[1]	-9	hSpCas9	negative selection	10846208
108355192	108355215	3	-	28162770	PL21	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.6203573528738442	[277]	[185]	5	hSpCas9	negative selection	10846209
108362353	108362376	3	+	28162770	P31FUJ	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.3294402198066939	[383]	[566]	3	hSpCas9	negative selection	11015566
108357933	108357956	3	+	28162770	P31FUJ	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.20396881681174667	[279]	[378]	2	hSpCas9	negative selection	11015567
108362393	108362416	3	-	28162770	P31FUJ	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.2578329137586244	[78]	[110]	2	hSpCas9	negative selection	11015568
108353755	108353778	3	+	28162770	P31FUJ	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.26969813611480464	[167]	[237]	3	hSpCas9	negative selection	11015569
108376506	108376529	3	-	28162770	P31FUJ	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.4405161707276245	[189]	[302]	5	hSpCas9	negative selection	11015570
108353690	108353713	3	+	28162770	P31FUJ	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.018736562581585847	[314]	[374]	0	hSpCas9	negative selection	11015571
108355349	108355372	3	+	28162770	P31FUJ	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	0.7306719195605074	[39]	[77]	8	hSpCas9	negative selection	11015572
108362425	108362448	3	+	28162770	P31FUJ	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.5756785039203199	[365]	[640]	6	hSpCas9	negative selection	11015573
108375747	108375770	3	+	28162770	P31FUJ	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	0.1233416058108967	[49]	[63]	1	hSpCas9	negative selection	11015574
108355192	108355215	3	-	28162770	P31FUJ	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.9214445831701326	[256]	[571]	9	hSpCas9	negative selection	11015575
108362353	108362376	3	+	28162770	OCIAML5	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	-0.6122875173305063	[270]	[319]	-4	hSpCas9	negative selection	11184932
108357933	108357956	3	+	28162770	OCIAML5	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.8598080423393787	[173]	[569]	7	hSpCas9	negative selection	11184933
108362393	108362416	3	-	28162770	OCIAML5	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	-0.37813538253158474	[53]	[74]	-3	hSpCas9	negative selection	11184934
108353755	108353778	3	+	28162770	OCIAML5	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.8546412022095282	[52]	[172]	7	hSpCas9	negative selection	11184935
108376506	108376529	3	-	28162770	OCIAML5	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.3763748951452559	[101]	[238]	3	hSpCas9	negative selection	11184936
108353690	108353713	3	+	28162770	OCIAML5	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	1.273028649117536	[137]	[601]	9	hSpCas9	negative selection	11184937
108355349	108355372	3	+	28162770	OCIAML5	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	0.4062454247273939	[50]	[121]	3	hSpCas9	negative selection	11184938
108362425	108362448	3	+	28162770	OCIAML5	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.5196145592204651	[227]	[589]	4	hSpCas9	negative selection	11184939
108375747	108375770	3	+	28162770	OCIAML5	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-1.328504614806984	[31]	[22]	-6	hSpCas9	negative selection	11184940
108355192	108355215	3	-	28162770	OCIAML5	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	1.5970820745114396	[127]	[698]	9	hSpCas9	negative selection	11184941
108362353	108362376	3	+	28162770	EOL1	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.2848194674184863	[697]	[447]	2	hSpCas9	negative selection	11354298
108357933	108357956	3	+	28162770	EOL1	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.2498401004912734	[256]	[160]	2	hSpCas9	negative selection	11354299
108362393	108362416	3	-	28162770	EOL1	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	1.5588982992538543	[133]	[207]	9	hSpCas9	negative selection	11354300
108353755	108353778	3	+	28162770	EOL1	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.323257100945378	[310]	[204]	3	hSpCas9	negative selection	11354301
108376506	108376529	3	-	28162770	EOL1	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.20862459296621538	[362]	[220]	2	hSpCas9	negative selection	11354302
108353690	108353713	3	+	28162770	EOL1	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.3712638571551611	[517]	[352]	3	hSpCas9	negative selection	11354303
108355349	108355372	3	+	28162770	EOL1	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	0.5694528127479725	[54]	[42]	5	hSpCas9	negative selection	11354304
108362425	108362448	3	+	28162770	EOL1	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.3180521092997371	[404]	[265]	3	hSpCas9	negative selection	11354305
108375747	108375770	3	+	28162770	EOL1	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	0.7439755259287137	[50]	[44]	6	hSpCas9	negative selection	11354306
108355192	108355215	3	-	28162770	EOL1	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	-0.4065113350689562	[316]	[125]	-3	hSpCas9	negative selection	11354307
108362353	108362376	3	+	28162770	MOLM13	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.5914928150573233	[748]	[815]	4	hSpCas9	negative selection	11523664
108357933	108357956	3	+	28162770	MOLM13	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	2.204232990341854	[231]	[772]	9	hSpCas9	negative selection	11523665
108362393	108362416	3	-	28162770	MOLM13	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.018363505880444553	[126]	[92]	0	hSpCas9	negative selection	11523666
108353755	108353778	3	+	28162770	MOLM13	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	1.4888744066739148	[272]	[553]	9	hSpCas9	negative selection	11523667
108376506	108376529	3	-	28162770	MOLM13	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.782204292322066	[303]	[377]	6	hSpCas9	negative selection	11523668
108353690	108353713	3	+	28162770	MOLM13	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	1.8940770053401446	[434]	[1168]	9	hSpCas9	negative selection	11523669
108355349	108355372	3	+	28162770	MOLM13	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	-1.8920065635418042	[76]	[14]	-7	hSpCas9	negative selection	11523670
108362425	108362448	3	+	28162770	MOLM13	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.1435453305377684	[384]	[251]	-1	hSpCas9	negative selection	11523671
108375747	108375770	3	+	28162770	MOLM13	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	1.732861591619865	[61]	[148]	9	hSpCas9	negative selection	11523672
108355192	108355215	3	-	28162770	MOLM13	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	1.1108350663721434	[316]	[494]	8	hSpCas9	negative selection	11523673
108362353	108362376	3	+	28162770	HEL	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.054091284471344814	[587]	[390]	0	hSpCas9	negative selection	11693030
108357933	108357956	3	+	28162770	HEL	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	1.043492105272953	[202]	[267]	8	hSpCas9	negative selection	11693031
108362393	108362416	3	-	28162770	HEL	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.2678904228372119	[117]	[90]	2	hSpCas9	negative selection	11693032
108353755	108353778	3	+	28162770	HEL	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.2317368459566697	[237]	[178]	2	hSpCas9	negative selection	11693033
108376506	108376529	3	-	28162770	HEL	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.7110081080173853	[226]	[237]	6	hSpCas9	negative selection	11693034
108353690	108353713	3	+	28162770	HEL	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	-0.1646160900572472	[447]	[255]	-1	hSpCas9	negative selection	11693035
108355349	108355372	3	+	28162770	HEL	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	-2.392885077730364	[40]	[4]	-8	hSpCas9	negative selection	11693036
108362425	108362448	3	+	28162770	HEL	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.18280479474719002	[358]	[260]	1	hSpCas9	negative selection	11693037
108375747	108375770	3	+	28162770	HEL	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	0.5813382873362134	[47]	[45]	5	hSpCas9	negative selection	11693038
108355192	108355215	3	-	28162770	HEL	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.16469153519571272	[272]	[195]	1	hSpCas9	negative selection	11693039
108362353	108362376	3	+	28162770	MV411	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	-0.007956792848886618	[338]	[283]	0	hSpCas9	negative selection	11862396
108357933	108357956	3	+	28162770	MV411	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	1.6612642274635716	[148]	[396]	9	hSpCas9	negative selection	11862397
108362393	108362416	3	-	28162770	MV411	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.5775861524751059	[69]	[87]	5	hSpCas9	negative selection	11862398
108353755	108353778	3	+	28162770	MV411	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.09093306510278457	[213]	[191]	0	hSpCas9	negative selection	11862399
108376506	108376529	3	-	28162770	MV411	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	1.0217247711547162	[144]	[247]	8	hSpCas9	negative selection	11862400
108353690	108353713	3	+	28162770	MV411	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	1.0530881666281304	[241]	[422]	8	hSpCas9	negative selection	11862401
108355349	108355372	3	+	28162770	MV411	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	0.5862394642345339	[33]	[42]	5	hSpCas9	negative selection	11862402
108362425	108362448	3	+	28162770	MV411	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.206298855989289	[248]	[241]	1	hSpCas9	negative selection	11862403
108375747	108375770	3	+	28162770	MV411	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-2.00048996266081	[37]	[7]	-8	hSpCas9	negative selection	11862404
108355192	108355215	3	-	28162770	MV411	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	-0.19014251714715685	[171]	[126]	-1	hSpCas9	negative selection	11862405
108362353	108362376	3	+	28162770	MONOMAC1	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.12371305663052723	[244]	[305]	1	hSpCas9	negative selection	12031762
108357933	108357956	3	+	28162770	MONOMAC1	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.8443830803204271	[102]	[211]	7	hSpCas9	negative selection	12031763
108362393	108362416	3	-	28162770	MONOMAC1	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.365557840633148	[64]	[95]	3	hSpCas9	negative selection	12031764
108353755	108353778	3	+	28162770	MONOMAC1	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	0.5525563554344016	[90]	[152]	5	hSpCas9	negative selection	12031765
108376506	108376529	3	-	28162770	MONOMAC1	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	0.587234461885009	[125]	[216]	6	hSpCas9	negative selection	12031766
108353690	108353713	3	+	28162770	MONOMAC1	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.2579670595369348	[177]	[243]	2	hSpCas9	negative selection	12031767
108355349	108355372	3	+	28162770	MONOMAC1	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	-4.0043917691171576	[27]	[1]	-9	hSpCas9	negative selection	12031768
108362425	108362448	3	+	28162770	MONOMAC1	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	0.6436966329968561	[176]	[316]	6	hSpCas9	negative selection	12031769
108375747	108375770	3	+	28162770	MONOMAC1	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-1.8668882453672229	[34]	[10]	-8	hSpCas9	negative selection	12031770
108355192	108355215	3	-	28162770	MONOMAC1	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.9192162214362943	[142]	[309]	8	hSpCas9	negative selection	12031771
108362353	108362376	3	+	28162770	OCIAML2	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.1651686408954287	[78]	[490]	1	hSpCas9	negative selection	12201128
108357933	108357956	3	+	28162770	OCIAML2	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	1.4458468191955554	[19]	[301]	9	hSpCas9	negative selection	12201129
108362393	108362416	3	-	28162770	OCIAML2	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	0.9163932978670858	[12]	[135]	8	hSpCas9	negative selection	12201130
108353755	108353778	3	+	28162770	OCIAML2	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	1.125920649754207	[30]	[374]	9	hSpCas9	negative selection	12201131
108376506	108376529	3	-	28162770	OCIAML2	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	-0.08158753449626191	[41]	[219]	0	hSpCas9	negative selection	12201132
108353690	108353713	3	+	28162770	OCIAML2	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.2697666743243182	[62]	[420]	2	hSpCas9	negative selection	12201133
108355349	108355372	3	+	28162770	OCIAML2	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	-0.544630406685938	[9]	[37]	-4	hSpCas9	negative selection	12201134
108362425	108362448	3	+	28162770	OCIAML2	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.12580132824472007	[49]	[253]	-1	hSpCas9	negative selection	12201135
108375747	108375770	3	+	28162770	OCIAML2	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	-0.47062982524216146	[7]	[31]	-4	hSpCas9	negative selection	12201136
108355192	108355215	3	-	28162770	OCIAML2	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	1.7860324981790325	[25]	[496]	9	hSpCas9	negative selection	12201137
108362353	108362376	3	+	28162770	OCIAML3	viability	GAAACAGCTTCCCATAACAAAGG	HHLA2	ENSG00000114455	0.39316831931825313	[112]	[447]	3	hSpCas9	negative selection	12370494
108357933	108357956	3	+	28162770	OCIAML3	viability	ACTTGGTCCAGAATGAAAAGTGG	HHLA2	ENSG00000114455	0.47638168756723487	[64]	[272]	4	hSpCas9	negative selection	12370495
108362393	108362416	3	-	28162770	OCIAML3	viability	AAAAGCTGCCAAAATCGCAGAGG	HHLA2	ENSG00000114455	-0.46155734430051365	[25]	[56]	-4	hSpCas9	negative selection	12370496
108353755	108353778	3	+	28162770	OCIAML3	viability	AAACAAAGTGGTGCTAAAGGTGG	HHLA2	ENSG00000114455	-0.3265273294591772	[53]	[129]	-3	hSpCas9	negative selection	12370497
108376506	108376529	3	-	28162770	OCIAML3	viability	TGGGACAGCGCTCACCAGGAGGG	HHLA2	ENSG00000114455	-0.9587719331217834	[46]	[72]	-6	hSpCas9	negative selection	12370498
108353690	108353713	3	+	28162770	OCIAML3	viability	AGAGTAAGCCTTCTGGACGAAGG	HHLA2	ENSG00000114455	0.5372368929540893	[83]	[367]	5	hSpCas9	negative selection	12370499
108355349	108355372	3	+	28162770	OCIAML3	viability	AGCAAACATGGACAGGGCGCTGG	HHLA2	ENSG00000114455	0.607626220845487	[4]	[22]	5	hSpCas9	negative selection	12370500
108362425	108362448	3	+	28162770	OCIAML3	viability	TGGAGCGTAAAATGTTGCAGAGG	HHLA2	ENSG00000114455	-0.23004432563958876	[114]	[295]	-2	hSpCas9	negative selection	12370501
108375747	108375770	3	+	28162770	OCIAML3	viability	CAGCCCAGCTAGAAGCCAGGAGG	HHLA2	ENSG00000114455	1.3908854672856288	[11]	[94]	9	hSpCas9	negative selection	12370502
108355192	108355215	3	-	28162770	OCIAML3	viability	TTCCACGTGATAATTGGACGAGG	HHLA2	ENSG00000114455	0.3353378061120513	[67]	[258]	3	hSpCas9	negative selection	12370503