Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:55662
• Symbol:HIF1AN
• Description:hypoxia inducible factor 1 subunit alpha inhibitor

DataSource: http://genomecrispr.dkfz.de/#!/results/HIF1AN

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
100546017	100546040	10	-	26472758	Jiyoye	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	0.4486946509441402	[136]	[140]	3	hSpCas9	negative selection	70684
100545051	100545074	10	-	26472758	Jiyoye	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	0.085247286618511	[59]	[47]	0	hSpCas9	negative selection	70685
100536085	100536108	10	-	26472758	Jiyoye	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.3640059279982458	[127]	[74]	-3	hSpCas9	negative selection	70686
100536630	100536653	10	+	26472758	Jiyoye	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	1.2343387846436578	[30]	[54]	7	hSpCas9	negative selection	70687
100540646	100540669	10	+	26472758	Jiyoye	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-1.381986423785761	[196]	[56]	-7	hSpCas9	negative selection	70688
100536562	100536585	10	+	26472758	Jiyoye	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	1.8275071804542302	[33]	[90]	8	hSpCas9	negative selection	70689
100540722	100540745	10	+	26472758	Jiyoye	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.8443633854900912	[49]	[20]	-5	hSpCas9	negative selection	70690
100545030	100545053	10	-	26472758	Jiyoye	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-0.1256986080668283	[67]	[46]	-1	hSpCas9	negative selection	70691
100547214	100547237	10	+	26472758	Jiyoye	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	1.1661672820020783	[38]	[65]	7	hSpCas9	negative selection	70692
100535987	100536010	10	-	26472758	Jiyoye	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.6177423674455318	[69]	[80]	4	hSpCas9	negative selection	70693
100529842	100529865	10	-	26472758	Jiyoye	viability	GAAGAAGGTGAAGATGGCGGTGG	HIF1AN	ENSG00000166135	-2.171763331587513	[238]	[39]	-8	hSpCas9	negative selection	107324
100529832	100529855	10	-	26472758	Jiyoye	viability	AAGATGGCGGTGGCCAGGGCCGG	HIF1AN	ENSG00000166135	-0.0004825874073729475	[64]	[48]	0	hSpCas9	negative selection	107325
100529475	100529498	10	-	26472758	Jiyoye	viability	TGACCAAGGACATGTTCCCGGGG	HIF1AN	ENSG00000166135	-1.1279559632632763	[312]	[107]	-6	hSpCas9	negative selection	107326
100529813	100529836	10	-	26472758	Jiyoye	viability	CCGGGGTCTTGGGAGTCCAGTGG	HIF1AN	ENSG00000166135	-1.8440497220382872	[218]	[45]	-8	hSpCas9	negative selection	107327
100529763	100529786	10	+	26472758	Jiyoye	viability	GGACCTGTCCGTGCGCCCAGCGG	HIF1AN	ENSG00000166135	-0.3529976038216579	[187]	[110]	-3	hSpCas9	negative selection	107328
100529421	100529444	10	+	26472758	Jiyoye	viability	CATATTATACTTCTTGGCGGCGG	HIF1AN	ENSG00000166135	0.08193455257767533	[108]	[86]	0	hSpCas9	negative selection	107329
100529458	100529481	10	+	26472758	Jiyoye	viability	GGGGTCCTAGGATAGGGCCCCGG	HIF1AN	ENSG00000166135	-0.4469737520306718	[46]	[25]	-3	hSpCas9	negative selection	107331
100529386	100529409	10	-	26472758	Jiyoye	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-1.0999675858483964	[414]	[145]	-6	hSpCas9	negative selection	107332
100546017	100546040	10	-	26472758	KBM7	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.9690605605610164	[607,450]	[99,148]	-6	hSpCas9	negative selection	261802
100545051	100545074	10	-	26472758	KBM7	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	0.6665164028368036	[140,208]	[136,130]	7	hSpCas9	negative selection	261803
100536085	100536108	10	-	26472758	KBM7	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.43151229664582824	[352,307]	[86,139]	-4	hSpCas9	negative selection	261804
100536630	100536653	10	+	26472758	KBM7	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-1.8410947715664996	[310,195]	[57,9]	-8	hSpCas9	negative selection	261805
100540646	100540669	10	+	26472758	KBM7	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.5741820750448372	[432,526]	[203,108]	-5	hSpCas9	negative selection	261806
100536562	100536585	10	+	26472758	KBM7	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.01907100272604123	[271,144]	[82,108]	0	hSpCas9	negative selection	261807
100540722	100540745	10	+	26472758	KBM7	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	0.4411808014863998	[77,104]	[76,43]	5	hSpCas9	negative selection	261808
100545030	100545053	10	-	26472758	KBM7	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-1.751823909453285	[335,197]	[36,35]	-8	hSpCas9	negative selection	261809
100547214	100547237	10	+	26472758	KBM7	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.4452441928538692	[256,354]	[198,200]	5	hSpCas9	negative selection	261810
100535987	100536010	10	-	26472758	KBM7	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.5169384173081162	[312,124]	[120,159]	5	hSpCas9	negative selection	261811
100529842	100529865	10	-	26472758	KBM7	viability	GAAGAAGGTGAAGATGGCGGTGG	HIF1AN	ENSG00000166135	-2.397907508925283	[671,466]	[28,68]	-9	hSpCas9	negative selection	298442
100529832	100529855	10	-	26472758	KBM7	viability	AAGATGGCGGTGGCCAGGGCCGG	HIF1AN	ENSG00000166135	0.9404239425366584	[160,175]	[68,228]	8	hSpCas9	negative selection	298443
100529475	100529498	10	-	26472758	KBM7	viability	TGACCAAGGACATGTTCCCGGGG	HIF1AN	ENSG00000166135	-0.9320509039981512	[1525,980]	[283,320]	-6	hSpCas9	negative selection	298444
100529813	100529836	10	-	26472758	KBM7	viability	CCGGGGTCTTGGGAGTCCAGTGG	HIF1AN	ENSG00000166135	-1.1180745053073762	[839,346]	[109,135]	-7	hSpCas9	negative selection	298445
100529763	100529786	10	+	26472758	KBM7	viability	GGACCTGTCCGTGCGCCCAGCGG	HIF1AN	ENSG00000166135	-0.3826309860812637	[986,635]	[426,162]	-4	hSpCas9	negative selection	298446
100529421	100529444	10	+	26472758	KBM7	viability	CATATTATACTTCTTGGCGGCGG	HIF1AN	ENSG00000166135	-0.5377555415682824	[668,444]	[213,144]	-5	hSpCas9	negative selection	298447
100529458	100529481	10	+	26472758	KBM7	viability	GGGGTCCTAGGATAGGGCCCCGG	HIF1AN	ENSG00000166135	1.2868846077799618	[97,55]	[89,82]	9	hSpCas9	negative selection	298449
100529386	100529409	10	-	26472758	KBM7	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.6894499610276879	[2040,1711]	[537,550]	-5	hSpCas9	negative selection	298450
100546017	100546040	10	-	26472758	Raji	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.03234122829301361	[259]	[58]	0	hSpCas9	negative selection	452920
100545051	100545074	10	-	26472758	Raji	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.0739462293409624	[126]	[27]	0	hSpCas9	negative selection	452921
100536085	100536108	10	-	26472758	Raji	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.410310668330906	[106]	[32]	4	hSpCas9	negative selection	452922
100536630	100536653	10	+	26472758	Raji	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-0.11103998375990287	[120]	[25]	-1	hSpCas9	negative selection	452923
100540646	100540669	10	+	26472758	Raji	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.5410367128197904	[153]	[51]	5	hSpCas9	negative selection	452924
100536562	100536585	10	+	26472758	Raji	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.2554821743627334	[147]	[40]	2	hSpCas9	negative selection	452925
100540722	100540745	10	+	26472758	Raji	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.5806724583116605	[57]	[8]	-4	hSpCas9	negative selection	452926
100545030	100545053	10	-	26472758	Raji	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-0.46336510612785586	[100]	[16]	-4	hSpCas9	negative selection	452927
100547214	100547237	10	+	26472758	Raji	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.5027922279035109	[221]	[72]	5	hSpCas9	negative selection	452928
100535987	100536010	10	-	26472758	Raji	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	-0.36555234761344557	[160]	[28]	-3	hSpCas9	negative selection	452929
100529842	100529865	10	-	26472758	Raji	viability	GAAGAAGGTGAAGATGGCGGTGG	HIF1AN	ENSG00000166135	-1.9927531359118507	[342]	[19]	-8	hSpCas9	negative selection	489560
100529832	100529855	10	-	26472758	Raji	viability	AAGATGGCGGTGGCCAGGGCCGG	HIF1AN	ENSG00000166135	-0.6551171508997442	[94]	[13]	-5	hSpCas9	negative selection	489561
100529475	100529498	10	-	26472758	Raji	viability	TGACCAAGGACATGTTCCCGGGG	HIF1AN	ENSG00000166135	-0.059676132374323565	[502]	[111]	0	hSpCas9	negative selection	489562
100529813	100529836	10	-	26472758	Raji	viability	CCGGGGTCTTGGGAGTCCAGTGG	HIF1AN	ENSG00000166135	-1.8969038230294986	[336]	[20]	-8	hSpCas9	negative selection	489563
100529763	100529786	10	+	26472758	Raji	viability	GGACCTGTCCGTGCGCCCAGCGG	HIF1AN	ENSG00000166135	-0.6965887472893524	[425]	[60]	-5	hSpCas9	negative selection	489564
100529421	100529444	10	+	26472758	Raji	viability	CATATTATACTTCTTGGCGGCGG	HIF1AN	ENSG00000166135	-0.5930561827674928	[402]	[61]	-5	hSpCas9	negative selection	489565
100529458	100529481	10	+	26472758	Raji	viability	GGGGTCCTAGGATAGGGCCCCGG	HIF1AN	ENSG00000166135	-1.4775789653475564	[47]	[3]	-8	hSpCas9	negative selection	489567
100529386	100529409	10	-	26472758	Raji	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.29339998022500247	[939]	[177]	-2	hSpCas9	negative selection	489568
100546017	100546040	10	-	26472758	K562	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	0.24441872766644698	[392]	[392]	1	hSpCas9	negative selection	644038
100545051	100545074	10	-	26472758	K562	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	1.7179059415251634	[129]	[360]	9	hSpCas9	negative selection	644039
100536085	100536108	10	-	26472758	K562	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.2378581090801454	[365]	[261]	-2	hSpCas9	negative selection	644040
100536630	100536653	10	+	26472758	K562	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	0.4799496184620194	[202]	[238]	4	hSpCas9	negative selection	644041
100540646	100540669	10	+	26472758	K562	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.008087966263435886	[354]	[297]	0	hSpCas9	negative selection	644042
100536562	100536585	10	+	26472758	K562	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.1706187716123968	[139]	[104]	-1	hSpCas9	negative selection	644043
100540722	100540745	10	+	26472758	K562	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-1.6574008783946503	[70]	[18]	-7	hSpCas9	negative selection	644044
100545030	100545053	10	-	26472758	K562	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	0.5578353226982918	[135]	[168]	4	hSpCas9	negative selection	644045
100547214	100547237	10	+	26472758	K562	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	-0.4224020424714819	[280]	[176]	-3	hSpCas9	negative selection	644046
100535987	100536010	10	-	26472758	K562	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.5169445824775385	[201]	[243]	4	hSpCas9	negative selection	644047
100529842	100529865	10	-	26472758	K562	viability	GAAGAAGGTGAAGATGGCGGTGG	HIF1AN	ENSG00000166135	-1.9805476373338273	[560]	[119]	-7	hSpCas9	negative selection	680678
100529832	100529855	10	-	26472758	K562	viability	AAGATGGCGGTGGCCAGGGCCGG	HIF1AN	ENSG00000166135	1.3404205475438007	[108]	[232]	9	hSpCas9	negative selection	680679
100529475	100529498	10	-	26472758	K562	viability	TGACCAAGGACATGTTCCCGGGG	HIF1AN	ENSG00000166135	-0.8203699988307028	[796]	[380]	-5	hSpCas9	negative selection	680680
100529813	100529836	10	-	26472758	K562	viability	CCGGGGTCTTGGGAGTCCAGTGG	HIF1AN	ENSG00000166135	-1.0295748901572135	[369]	[152]	-5	hSpCas9	negative selection	680681
100529763	100529786	10	+	26472758	K562	viability	GGACCTGTCCGTGCGCCCAGCGG	HIF1AN	ENSG00000166135	0.5457086525102419	[520]	[641]	4	hSpCas9	negative selection	680682
100529421	100529444	10	+	26472758	K562	viability	CATATTATACTTCTTGGCGGCGG	HIF1AN	ENSG00000166135	-0.26687186117400996	[438]	[307]	-2	hSpCas9	negative selection	680683
100529458	100529481	10	+	26472758	K562	viability	GGGGTCCTAGGATAGGGCCCCGG	HIF1AN	ENSG00000166135	1.123564332792061	[55]	[102]	8	hSpCas9	negative selection	680685
100529386	100529409	10	-	26472758	K562	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.033759164427888955	[1493]	[1231]	0	hSpCas9	negative selection	680686
100536080	100536103	10	-	26627737	DLD1	viability	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.5809351556045889	[415]	[143,247,193]	6	hSpCas9	negative selection	773290
100536085	100536108	10	-	26627737	DLD1	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.07732419549412695	[934]	[260,323,251]	-1	hSpCas9	negative selection	773291
100536627	100536650	10	+	26627737	DLD1	viability	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	2.628544441262604	[35]	[48,51,101]	9	hSpCas9	negative selection	773292
100540760	100540783	10	-	26627737	DLD1	viability	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.6376037375068506	[123]	[101,170,94]	9	hSpCas9	negative selection	773293
100545076	100545099	10	-	26627737	DLD1	viability	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-0.8278294576362231	[220]	[51,35,29]	-7	hSpCas9	negative selection	773294
100546000	100546023	10	+	26627737	DLD1	viability	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	0.2765982760099469	[230]	[58,112,90]	3	hSpCas9	negative selection	773295
100536080	100536103	10	-	26627737	GBM cells	viability after 5 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.4838763756068419	[211]	[174,142]	7	hSpCas9	negative selection	855605
100536085	100536108	10	-	26627737	GBM cells	viability after 5 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.5040817981218967	[516]	[197,192]	-7	hSpCas9	negative selection	855606
100536627	100536650	10	+	26627737	GBM cells	viability after 5 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	1.2774254981394155	[24]	[30,33]	9	hSpCas9	negative selection	855607
100540760	100540783	10	-	26627737	GBM cells	viability after 5 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	0.31117428949395576	[129]	[85,86]	5	hSpCas9	negative selection	855608
100545076	100545099	10	-	26627737	GBM cells	viability after 5 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.28163365389180095	[78]	[54,47]	4	hSpCas9	negative selection	855609
100546000	100546023	10	+	26627737	GBM cells	viability after 5 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	0.8198423038944868	[149]	[146,136]	9	hSpCas9	negative selection	855610
100536080	100536103	10	-	26627737	GBM cells	viability after 13 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.551165135536553	[211]	[226,120]	7	hSpCas9	negative selection	937920
100536085	100536108	10	-	26627737	GBM cells	viability after 13 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.6110676039109021	[516]	[256,123]	-6	hSpCas9	negative selection	937921
100536627	100536650	10	+	26627737	GBM cells	viability after 13 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	0.5553934903910953	[24]	[25,14]	7	hSpCas9	negative selection	937922
100540760	100540783	10	-	26627737	GBM cells	viability after 13 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.3515943306573297	[129]	[62,48]	-4	hSpCas9	negative selection	937923
100545076	100545099	10	-	26627737	GBM cells	viability after 13 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.3336027148826628	[78]	[85,27]	4	hSpCas9	negative selection	937924
100546000	100546023	10	+	26627737	GBM cells	viability after 13 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	0.44779586430144447	[149]	[126,97]	5	hSpCas9	negative selection	937925
100536080	100536103	10	-	26627737	GBM cells	viability after 21 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.22817820657353857	[211]	[136,132]	2	hSpCas9	negative selection	1020235
100536085	100536108	10	-	26627737	GBM cells	viability after 21 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.9239006283545996	[516]	[146,148]	-7	hSpCas9	negative selection	1020236
100536627	100536650	10	+	26627737	GBM cells	viability after 21 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	1.7803540863462761	[24]	[42,49]	9	hSpCas9	negative selection	1020237
100540760	100540783	10	-	26627737	GBM cells	viability after 21 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.09385957116037069	[129]	[61,69]	-1	hSpCas9	negative selection	1020238
100545076	100545099	10	-	26627737	GBM cells	viability after 21 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.061163578524210394	[78]	[49,39]	0	hSpCas9	negative selection	1020239
100546000	100546023	10	+	26627737	GBM cells	viability after 21 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	0.2104304760808391	[149]	[110,78]	2	hSpCas9	negative selection	1020240
100536080	100536103	10	-	26627737	RPE1	viability after 9 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.47799678357861497	[514]	[162,303]	3	hSpCas9	negative selection	1102550
100536085	100536108	10	-	26627737	RPE1	viability after 9 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.09519591876883676	[1028]	[277,331]	0	hSpCas9	negative selection	1102551
100536627	100536650	10	+	26627737	RPE1	viability after 9 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	2.375365137725706	[17]	[23,35]	9	hSpCas9	negative selection	1102552
100540760	100540783	10	-	26627737	RPE1	viability after 9 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.1517447272026722	[444]	[357,246]	7	hSpCas9	negative selection	1102553
100545076	100545099	10	-	26627737	RPE1	viability after 9 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	2.092639641334259	[72]	[86,110]	9	hSpCas9	negative selection	1102554
100546000	100546023	10	+	26627737	RPE1	viability after 9 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.11755113279339025	[306]	[71,109]	-1	hSpCas9	negative selection	1102555
100536080	100536103	10	-	26627737	RPE1	viability after 12 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	1.0726997745551246	[514]	[189,397]	6	hSpCas9	negative selection	1184865
100536085	100536108	10	-	26627737	RPE1	viability after 12 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.4629435569738742	[1028]	[219,179]	-3	hSpCas9	negative selection	1184866
100536627	100536650	10	+	26627737	RPE1	viability after 12 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	2.08474342710891	[17]	[20,19]	9	hSpCas9	negative selection	1184867
100540760	100540783	10	-	26627737	RPE1	viability after 12 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.0776913256525806	[444]	[314,185]	6	hSpCas9	negative selection	1184868
100545076	100545099	10	-	26627737	RPE1	viability after 12 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	1.7961723563103158	[72]	[88,45]	8	hSpCas9	negative selection	1184869
100546000	100546023	10	+	26627737	RPE1	viability after 12 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	0.6446046125704792	[306]	[126,130]	4	hSpCas9	negative selection	1184870
100536080	100536103	10	-	26627737	RPE1	viability after 15 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.6683578181915573	[514]	[229,232]	4	hSpCas9	negative selection	1267180
100536085	100536108	10	-	26627737	RPE1	viability after 15 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.689965963880018	[1028]	[127,230]	-4	hSpCas9	negative selection	1267181
100536627	100536650	10	+	26627737	RPE1	viability after 15 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	3.4022921470860044	[17]	[34,71]	9	hSpCas9	negative selection	1267182
100540760	100540783	10	-	26627737	RPE1	viability after 15 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	0.8429225278041302	[444]	[321,132]	5	hSpCas9	negative selection	1267183
100545076	100545099	10	-	26627737	RPE1	viability after 15 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-0.31343146895591234	[72]	[9,22]	-2	hSpCas9	negative selection	1267184
100546000	100546023	10	+	26627737	RPE1	viability after 15 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	0.9381695748461801	[306]	[171,160]	5	hSpCas9	negative selection	1267185
100536080	100536103	10	-	26627737	RPE1	viability after 18 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.09287294598908402	[514]	[124,135]	0	hSpCas9	negative selection	1349495
100536085	100536108	10	-	26627737	RPE1	viability after 18 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.5831713922146182	[1028]	[122,251]	-4	hSpCas9	negative selection	1349496
100536627	100536650	10	+	26627737	RPE1	viability after 18 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	2.6179470253669312	[17]	[9,50]	9	hSpCas9	negative selection	1349497
100540760	100540783	10	-	26627737	RPE1	viability after 18 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.1988704276831346	[444]	[280,269]	6	hSpCas9	negative selection	1349498
100545076	100545099	10	-	26627737	RPE1	viability after 18 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	1.4528306695289337	[72]	[80,24]	7	hSpCas9	negative selection	1349499
100546000	100546023	10	+	26627737	RPE1	viability after 18 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.1561519537844731	[306]	[69,78]	-1	hSpCas9	negative selection	1349500
100536080	100536103	10	-	26627737	HeLa	viability after 8 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.5146368111888593	[350]	[165,123,343]	4	hSpCas9	negative selection	1431810
100536085	100536108	10	-	26627737	HeLa	viability after 8 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.010823754056751733	[902]	[394,310,459]	0	hSpCas9	negative selection	1431811
100536627	100536650	10	+	26627737	HeLa	viability after 8 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-1.0747057687583506	[135]	[17,34,28]	-8	hSpCas9	negative selection	1431812
100540760	100540783	10	-	26627737	HeLa	viability after 8 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	0.06384678789720782	[327]	[208,91,158]	0	hSpCas9	negative selection	1431813
100545076	100545099	10	-	26627737	HeLa	viability after 8 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-0.7143827255649075	[200]	[155,9,18]	-6	hSpCas9	negative selection	1431814
100546000	100546023	10	+	26627737	HeLa	viability after 8 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.4674748585267431	[243]	[255,13,4]	-4	hSpCas9	negative selection	1431815
100536080	100536103	10	-	26627737	HeLa	viability after 12 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.4912408414189646	[350]	[185,214,208]	4	hSpCas9	negative selection	1514125
100536085	100536108	10	-	26627737	HeLa	viability after 12 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.06893746151491253	[902]	[382,299,390]	0	hSpCas9	negative selection	1514126
100536627	100536650	10	+	26627737	HeLa	viability after 12 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-1.0099771827604864	[135]	[31,16,35]	-7	hSpCas9	negative selection	1514127
100540760	100540783	10	-	26627737	HeLa	viability after 12 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.29712715109226556	[327]	[152,149,24]	-3	hSpCas9	negative selection	1514128
100545076	100545099	10	-	26627737	HeLa	viability after 12 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-0.29075304947546055	[200]	[119,3,87]	-3	hSpCas9	negative selection	1514129
100546000	100546023	10	+	26627737	HeLa	viability after 12 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.11791765637585128	[243]	[107,75,96]	-1	hSpCas9	negative selection	1514130
100536080	100536103	10	-	26627737	HeLa	viability after 15 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.42350554320834327	[350]	[53,90,180]	-4	hSpCas9	negative selection	1596440
100536085	100536108	10	-	26627737	HeLa	viability after 15 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.6008774066363035	[902]	[202,229,298]	-5	hSpCas9	negative selection	1596441
100536627	100536650	10	+	26627737	HeLa	viability after 15 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.7525485815894992	[135]	[19,54,22]	-6	hSpCas9	negative selection	1596442
100540760	100540783	10	-	26627737	HeLa	viability after 15 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.9367976735014745	[327]	[98,74,31]	-7	hSpCas9	negative selection	1596443
100545076	100545099	10	-	26627737	HeLa	viability after 15 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-1.358962460738033	[200]	[51,28,12]	-8	hSpCas9	negative selection	1596444
100546000	100546023	10	+	26627737	HeLa	viability after 15 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.7097988339892308	[243]	[84,70,22]	-6	hSpCas9	negative selection	1596445
100536080	100536103	10	-	26627737	HeLa	viability after 18 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.4256827137305052	[350]	[36,73,180]	-4	hSpCas9	negative selection	1678755
100536085	100536108	10	-	26627737	HeLa	viability after 18 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.6062825911616152	[902]	[133,190,298]	-5	hSpCas9	negative selection	1678756
100536627	100536650	10	+	26627737	HeLa	viability after 18 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.7224521044703103	[135]	[15,43,22]	-6	hSpCas9	negative selection	1678757
100540760	100540783	10	-	26627737	HeLa	viability after 18 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.9811446947862212	[327]	[63,59,31]	-7	hSpCas9	negative selection	1678758
100545076	100545099	10	-	26627737	HeLa	viability after 18 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-1.399049916228086	[200]	[33,22,12]	-8	hSpCas9	negative selection	1678759
100546000	100546023	10	+	26627737	HeLa	viability after 18 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.717931960775125	[243]	[56,57,22]	-6	hSpCas9	negative selection	1678760
100536080	100536103	10	-	26627737	HCT116	viability after 6 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-2.0722771069082926	[1092]	[94,10]	-8	hSpCas9	negative selection	1761070
100536085	100536108	10	-	26627737	HCT116	viability after 6 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.02637109488227285	[1554]	[315,211]	0	hSpCas9	negative selection	1761071
100536627	100536650	10	+	26627737	HCT116	viability after 6 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	2.5579554221814744	[2]	[5,0]	9	hSpCas9	negative selection	1761072
100540760	100540783	10	-	26627737	HCT116	viability after 6 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.5189022703223864	[119]	[84,36]	7	hSpCas9	negative selection	1761073
100545076	100545099	10	-	26627737	HCT116	viability after 6 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.010178893173258263	[142]	[50,6]	0	hSpCas9	negative selection	1761074
100546000	100546023	10	+	26627737	HCT116	viability after 6 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-1.0322756653694116	[910]	[60,74]	-5	hSpCas9	negative selection	1761075
100536080	100536103	10	-	26627737	HCT116	viability after 8 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.02498800700760522	[301]	[133,94,276]	0	hSpCas9	negative selection	1843385
100536085	100536108	10	-	26627737	HCT116	viability after 8 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.229744731230066	[652]	[256,383,278]	-3	hSpCas9	negative selection	1843386
100536627	100536650	10	+	26627737	HCT116	viability after 8 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	6.61402684480271	[0]	[6,92,60]	9	hSpCas9	negative selection	1843387
100540760	100540783	10	-	26627737	HCT116	viability after 8 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	0.786513104098986	[98]	[103,45,131]	7	hSpCas9	negative selection	1843388
100545076	100545099	10	-	26627737	HCT116	viability after 8 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.23140060492556058	[60]	[12,72,31]	2	hSpCas9	negative selection	1843389
100546000	100546023	10	+	26627737	HCT116	viability after 8 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.805547994344896	[370]	[87,196,65]	-7	hSpCas9	negative selection	1843390
100536080	100536103	10	-	26627737	HCT116	viability after 9 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-1.077928701105878	[1092]	[173,109]	-6	hSpCas9	negative selection	1925700
100536085	100536108	10	-	26627737	HCT116	viability after 9 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-2.0209577862902104	[1554]	[127,81]	-8	hSpCas9	negative selection	1925701
100536627	100536650	10	+	26627737	HCT116	viability after 9 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	4.820806400162862	[2]	[6,34]	9	hSpCas9	negative selection	1925702
100540760	100540783	10	-	26627737	HCT116	viability after 9 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.5753337995233796	[119]	[30,13]	-4	hSpCas9	negative selection	1925703
100545076	100545099	10	-	26627737	HCT116	viability after 9 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-0.717820569915407	[142]	[44,5]	-5	hSpCas9	negative selection	1925704
100546000	100546023	10	+	26627737	HCT116	viability after 9 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.1767952440609485	[910]	[446,31]	-1	hSpCas9	negative selection	1925705
100536080	100536103	10	-	26627737	HCT116	viability after 12 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.2596723799576569	[301]	[113,118,165]	-3	hSpCas9	negative selection	2008015
100536085	100536108	10	-	26627737	HCT116	viability after 12 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.231316527733206	[652]	[192,303,388]	-2	hSpCas9	negative selection	2008016
100536627	100536650	10	+	26627737	HCT116	viability after 12 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	6.0633561912714455	[0]	[19,44,41]	9	hSpCas9	negative selection	2008017
100540760	100540783	10	-	26627737	HCT116	viability after 12 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	0.7126514531868454	[98]	[114,77,59]	6	hSpCas9	negative selection	2008018
100545076	100545099	10	-	26627737	HCT116	viability after 12 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-0.3088262313380534	[60]	[1,77,0]	-3	hSpCas9	negative selection	2008019
100546000	100546023	10	+	26627737	HCT116	viability after 12 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.9769636224140614	[370]	[111,97,85]	-8	hSpCas9	negative selection	2008020
100536080	100536103	10	-	26627737	HCT116	viability after 15 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.2842500502919483	[301]	[267,199,172]	3	hSpCas9	negative selection	2090330
100536085	100536108	10	-	26627737	HCT116	viability after 15 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.29594167037124985	[652]	[308,399,208]	-3	hSpCas9	negative selection	2090331
100536627	100536650	10	+	26627737	HCT116	viability after 15 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	5.824046198236597	[0]	[19,36,38]	9	hSpCas9	negative selection	2090332
100540760	100540783	10	-	26627737	HCT116	viability after 15 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.6678726861400175	[98]	[284,116,152]	9	hSpCas9	negative selection	2090333
100545076	100545099	10	-	26627737	HCT116	viability after 15 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-0.6522557573375818	[60]	[12,51,0]	-6	hSpCas9	negative selection	2090334
100546000	100546023	10	+	26627737	HCT116	viability after 15 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-1.4426459343549147	[370]	[81,108,44]	-8	hSpCas9	negative selection	2090335
100536080	100536103	10	-	26627737	HCT116	viability after 18 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.05190568071370286	[301]	[126,73,229]	0	hSpCas9	negative selection	2172645
100536085	100536108	10	-	26627737	HCT116	viability after 18 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.36225565291338757	[652]	[215,272,245]	-3	hSpCas9	negative selection	2172646
100536627	100536650	10	+	26627737	HCT116	viability after 18 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	5.441071647728716	[0]	[24,27,8]	9	hSpCas9	negative selection	2172647
100540760	100540783	10	-	26627737	HCT116	viability after 18 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.289031509406403	[98]	[173,100,74]	8	hSpCas9	negative selection	2172648
100545076	100545099	10	-	26627737	HCT116	viability after 18 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-3.6122292156206015	[60]	[0,4,0]	-9	hSpCas9	negative selection	2172649
100546000	100546023	10	+	26627737	HCT116	viability after 18 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.619304252059578	[370]	[182,91,74]	-5	hSpCas9	negative selection	2172650
100535952	100535975	10	+	24336569	HL60	viability	GGCGGAGATGGCGGCGACAGCGG	HIF1AN	ENSG00000166135	0.3602717200407354	[260]	[708]	3	hSpCas9	negative selection	2269622
100535964	100535987	10	+	24336569	HL60	viability	GGCGACAGCGGCGGAGGCTGTGG	HIF1AN	ENSG00000166135	-0.6186103658633771	[956]	[1318]	-5	hSpCas9	negative selection	2269623
100535971	100535994	10	+	24336569	HL60	viability	GCGGCGGAGGCTGTGGCCTCTGG	HIF1AN	ENSG00000166135	-0.8573187081886975	[469]	[548]	-7	hSpCas9	negative selection	2269624
100535977	100536000	10	+	24336569	HL60	viability	GAGGCTGTGGCCTCTGGCTCTGG	HIF1AN	ENSG00000166135	5.088460900813415	[0]	[71]	9	hSpCas9	negative selection	2269625
100536005	100536028	10	-	24336569	HL60	viability	GAGGGCTCCAGCCTCCTCCCGGG	HIF1AN	ENSG00000166135	0.5034984000922597	[184]	[554]	4	hSpCas9	negative selection	2269626
100536031	100536054	10	-	24336569	HL60	viability	AACTGGGATTCATCCCAGGCGGG	HIF1AN	ENSG00000166135	0.4490506160698837	[71]	[207]	4	hSpCas9	negative selection	2269627
100536047	100536070	10	-	24336569	HL60	viability	GAAGCTATAACTGCGCAACTGGG	HIF1AN	ENSG00000166135	1.6561286159296618	[229]	[1533]	9	hSpCas9	negative selection	2269628
100536056	100536079	10	+	24336569	HL60	viability	GCAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.31130779652554186	[274]	[468]	-3	hSpCas9	negative selection	2269629
100536069	100536092	10	-	24336569	HL60	viability	GACGCGGAATGGGCCTAGTCGGG	HIF1AN	ENSG00000166135	0.272900348853163	[430]	[1101]	2	hSpCas9	negative selection	2269630
100536079	100536102	10	-	24336569	HL60	viability	CTCTGACTCAGACGCGGAATGGG	HIF1AN	ENSG00000166135	-0.38812543886294815	[469]	[759]	-3	hSpCas9	negative selection	2269631
100535952	100535975	10	+	24336569	KBM7	viability	GGCGGAGATGGCGGCGACAGCGG	HIF1AN	ENSG00000166135	-1.7274733356358865	[481]	[396]	-8	hSpCas9	negative selection	2336799
100535964	100535987	10	+	24336569	KBM7	viability	GGCGACAGCGGCGGAGGCTGTGG	HIF1AN	ENSG00000166135	-3.7109282921081883	[916]	[190]	-9	hSpCas9	negative selection	2336800
100535971	100535994	10	+	24336569	KBM7	viability	GCGGCGGAGGCTGTGGCCTCTGG	HIF1AN	ENSG00000166135	-0.19554303425721742	[405]	[966]	-2	hSpCas9	negative selection	2336801
100535977	100536000	10	+	24336569	KBM7	viability	GAGGCTGTGGCCTCTGGCTCTGG	HIF1AN	ENSG00000166135	0.6730505086366563	[42]	[186]	6	hSpCas9	negative selection	2336802
100536005	100536028	10	-	24336569	KBM7	viability	GAGGGCTCCAGCCTCCTCCCGGG	HIF1AN	ENSG00000166135	-0.8452346175994899	[219]	[333]	-6	hSpCas9	negative selection	2336803
100536031	100536054	10	-	24336569	KBM7	viability	AACTGGGATTCATCCCAGGCGGG	HIF1AN	ENSG00000166135	-0.475593572718479	[129]	[254]	-4	hSpCas9	negative selection	2336804
100536047	100536070	10	-	24336569	KBM7	viability	GAAGCTATAACTGCGCAACTGGG	HIF1AN	ENSG00000166135	-0.46017923332851596	[229]	[455]	-4	hSpCas9	negative selection	2336805
100536056	100536079	10	+	24336569	KBM7	viability	GCAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.7921624970965554	[352]	[555]	-6	hSpCas9	negative selection	2336806
100536069	100536092	10	-	24336569	KBM7	viability	GACGCGGAATGGGCCTAGTCGGG	HIF1AN	ENSG00000166135	-0.7365926689635098	[649]	[1063]	-5	hSpCas9	negative selection	2336807
100536079	100536102	10	-	24336569	KBM7	viability	CTCTGACTCAGACGCGGAATGGG	HIF1AN	ENSG00000166135	0.07337669172505273	[529]	[1520]	0	hSpCas9	negative selection	2336808
100530079	100530102	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTCAGCTCAGGGAGAAAAAGG	HIF1AN	ENSG00000166135	0.776400318403462	[97,153]	[56,36]	3	dCas9-VP64	positive selection	2437121
100530017	100530040	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAAGGATAAGCGGGAAGAAGG	HIF1AN	ENSG00000166135	2.786319801571347	[1,15]	[0,28]	8	dCas9-VP64	positive selection	2437122
100530045	100530068	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAAATGTCAGAGACCTGCCTGG	HIF1AN	ENSG00000166135	0.36234087061105263	[92,112]	[35,20]	1	dCas9-VP64	positive selection	2437123
100535737	100535760	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCTCCACTGCTGAAGAAATGG	HIF1AN	ENSG00000166135	0.8499590805190911	[105,81]	[35,37]	3	dCas9-VP64	positive selection	2449220
100535716	100535739	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGCTAGACACTAGTCCCACGG	HIF1AN	ENSG00000166135	1.0946835309654999	[30,93]	[16,42]	4	dCas9-VP64	positive selection	2449221
100535766	100535789	10	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAGAGCTGCATACTACCATTAGG	HIF1AN	ENSG00000166135	0.5333245820224257	[384,188]	[20,165]	2	dCas9-VP64	positive selection	2449222
100533128	100533151	10	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCGCTTGAATCCCGG	HIF1AN	ENSG00000166135	1.579452491414227	[20,39]	[3,36]	6	dCas9-VP64	positive selection	2477185
100530079	100530102	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTCAGCTCAGGGAGAAAAAGG	HIF1AN	ENSG00000166135	3.0725308845071337	[50,116]	[147,308]	9	dCas9-VP64	positive selection	2532376
100530017	100530040	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAAGGATAAGCGGGAAGAAGG	HIF1AN	ENSG00000166135	0.19021483372595238	[17,46]	[1,19]	1	dCas9-VP64	positive selection	2532377
100530045	100530068	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAAATGTCAGAGACCTGCCTGG	HIF1AN	ENSG00000166135	-0.8730357647296139	[211,140]	[23,37]	-7	dCas9-VP64	positive selection	2532378
100535737	100535760	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCTCCACTGCTGAAGAAATGG	HIF1AN	ENSG00000166135	-0.2752428073138071	[215,184]	[49,56]	-3	dCas9-VP64	positive selection	2544475
100535716	100535739	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGCTAGACACTAGTCCCACGG	HIF1AN	ENSG00000166135	0.9383128007296876	[76,61]	[33,51]	6	dCas9-VP64	positive selection	2544476
100535766	100535789	10	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAGAGCTGCATACTACCATTAGG	HIF1AN	ENSG00000166135	2.186599244298971	[110,180]	[49,371]	8	dCas9-VP64	positive selection	2544477
100533128	100533151	10	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCGCTTGAATCCCGG	HIF1AN	ENSG00000166135	0.3334805796334224	[96,125]	[24,64]	2	dCas9-VP64	positive selection	2572440
100536005	100536028	10	-	27260157	DLD1	viability	GAGGGCTCCAGCCTCCTCCCGGG	HIF1AN	ENSG00000166135	-0.0738787640012962	[]	[]	0	hSpCas9	negative selection	2580754
100536517	100536540	10	-	27260157	DLD1	viability	GTACAAGAACTTGTGGGTGCTGG	HIF1AN	ENSG00000166135	-1.6177125987928	[]	[]	-8	hSpCas9	negative selection	2581693
100535943	100535966	10	+	27260157	DLD1	viability	GTCCCTGGCGGCGGAGATGGCGG	HIF1AN	ENSG00000166135	-2.02417906556053	[]	[]	-8	hSpCas9	negative selection	2582359
100536069	100536092	10	-	27260157	DLD1	viability	GACGCGGAATGGGCCTAGTCGGG	HIF1AN	ENSG00000166135	0.745775677971302	[]	[]	8	hSpCas9	negative selection	2585876
100536105	100536128	10	-	27260157	DLD1	viability	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	0.0338117474476088	[]	[]	0	hSpCas9	negative selection	2606807
100536047	100536070	10	-	27260157	DLD1	viability	GAAGCTATAACTGCGCAACTGGG	HIF1AN	ENSG00000166135	0.0634542635011982	[]	[]	3	hSpCas9	negative selection	2608173
100536414	100536437	10	-	27260157	DLD1	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.291098295331747	[]	[]	-2	hSpCas9	negative selection	2609523
100535964	100535987	10	+	27260157	DLD1	viability	GGCGACAGCGGCGGAGGCTGTGG	HIF1AN	ENSG00000166135	-0.980253572632224	[]	[]	-7	hSpCas9	negative selection	2611194
100536439	100536462	10	+	27260157	DLD1	viability	TTGTGTATCCTGCCCTGAAATGG	HIF1AN	ENSG00000166135	-1.09589943948246	[]	[]	-7	hSpCas9	negative selection	2611669
100536031	100536054	10	-	27260157	DLD1	viability	AACTGGGATTCATCCCAGGCGGG	HIF1AN	ENSG00000166135	-0.442949017040611	[]	[]	-4	hSpCas9	negative selection	2613599
100536447	100536470	10	-	27260157	DLD1	viability	TCAAGGTCCCATTTCAGGGCAGG	HIF1AN	ENSG00000166135	-0.521058403878834	[]	[]	-4	hSpCas9	negative selection	2614654
100536079	100536102	10	-	27260157	DLD1	viability	CTCTGACTCAGACGCGGAATGGG	HIF1AN	ENSG00000166135	0.278153904959728	[]	[]	4	hSpCas9	negative selection	2617247
100535977	100536000	10	+	27260157	DLD1	viability	GAGGCTGTGGCCTCTGGCTCTGG	HIF1AN	ENSG00000166135	-0.399773896299575	[]	[]	-3	hSpCas9	negative selection	2620249
100535952	100535975	10	+	27260157	DLD1	viability	GGCGGAGATGGCGGCGACAGCGG	HIF1AN	ENSG00000166135	0.183692387430492	[]	[]	3	hSpCas9	negative selection	2621537
100535971	100535994	10	+	27260157	DLD1	viability	GCGGCGGAGGCTGTGGCCTCTGG	HIF1AN	ENSG00000166135	-0.156502051891086	[]	[]	-1	hSpCas9	negative selection	2641611
100536056	100536079	10	+	27260157	DLD1	viability	GCAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.4222579615709	[]	[]	-3	hSpCas9	negative selection	2642110
100536030	100536053	10	-	27260157	DLD1	viability	ACTGGGATTCATCCCAGGCGGGG	HIF1AN	ENSG00000166135	0.276669951730799	[]	[]	4	hSpCas9	negative selection	2647664
100535941	100535964	10	-	27260157	DLD1	viability	GCCATCTCCGCCGCCAGGGACGG	HIF1AN	ENSG00000166135	0.801249976707901	[]	[]	9	hSpCas9	negative selection	2647696
100536005	100536028	10	-	27260157	HT1080	viability	GAGGGCTCCAGCCTCCTCCCGGG	HIF1AN	ENSG00000166135	-0.238588694293489	[]	[]	0	hSpCas9	negative selection	2656884
100536517	100536540	10	-	27260157	HT1080	viability	GTACAAGAACTTGTGGGTGCTGG	HIF1AN	ENSG00000166135	-0.474437228843988	[]	[]	-7	hSpCas9	negative selection	2657823
100535943	100535966	10	+	27260157	HT1080	viability	GTCCCTGGCGGCGGAGATGGCGG	HIF1AN	ENSG00000166135	-0.138339709501768	[]	[]	0	hSpCas9	negative selection	2658489
100536069	100536092	10	-	27260157	HT1080	viability	GACGCGGAATGGGCCTAGTCGGG	HIF1AN	ENSG00000166135	0.789395686402982	[]	[]	7	hSpCas9	negative selection	2662006
100536105	100536128	10	-	27260157	HT1080	viability	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	-0.838441351389442	[]	[]	-8	hSpCas9	negative selection	2682937
100536047	100536070	10	-	27260157	HT1080	viability	GAAGCTATAACTGCGCAACTGGG	HIF1AN	ENSG00000166135	0.108890277771591	[]	[]	1	hSpCas9	negative selection	2684303
100536414	100536437	10	-	27260157	HT1080	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.953758707996369	[]	[]	-8	hSpCas9	negative selection	2685653
100535964	100535987	10	+	27260157	HT1080	viability	GGCGACAGCGGCGGAGGCTGTGG	HIF1AN	ENSG00000166135	-1.15964810341405	[]	[]	-8	hSpCas9	negative selection	2687324
100536439	100536462	10	+	27260157	HT1080	viability	TTGTGTATCCTGCCCTGAAATGG	HIF1AN	ENSG00000166135	0.178299435183953	[]	[]	1	hSpCas9	negative selection	2687799
100536031	100536054	10	-	27260157	HT1080	viability	AACTGGGATTCATCCCAGGCGGG	HIF1AN	ENSG00000166135	0.35349883504665	[]	[]	3	hSpCas9	negative selection	2689729
100536447	100536470	10	-	27260157	HT1080	viability	TCAAGGTCCCATTTCAGGGCAGG	HIF1AN	ENSG00000166135	-0.000889875803305337	[]	[]	0	hSpCas9	negative selection	2690784
100536079	100536102	10	-	27260157	HT1080	viability	CTCTGACTCAGACGCGGAATGGG	HIF1AN	ENSG00000166135	0.681810434892158	[]	[]	6	hSpCas9	negative selection	2693377
100535977	100536000	10	+	27260157	HT1080	viability	GAGGCTGTGGCCTCTGGCTCTGG	HIF1AN	ENSG00000166135	-0.370140758162726	[]	[]	-7	hSpCas9	negative selection	2696379
100535952	100535975	10	+	27260157	HT1080	viability	GGCGGAGATGGCGGCGACAGCGG	HIF1AN	ENSG00000166135	0.498947299796817	[]	[]	4	hSpCas9	negative selection	2697667
100535971	100535994	10	+	27260157	HT1080	viability	GCGGCGGAGGCTGTGGCCTCTGG	HIF1AN	ENSG00000166135	0.416460648838489	[]	[]	4	hSpCas9	negative selection	2717741
100536056	100536079	10	+	27260157	HT1080	viability	GCAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.707294664767583	[]	[]	-8	hSpCas9	negative selection	2718240
100536030	100536053	10	-	27260157	HT1080	viability	ACTGGGATTCATCCCAGGCGGGG	HIF1AN	ENSG00000166135	-0.105837546837347	[]	[]	0	hSpCas9	negative selection	2723794
100535941	100535964	10	-	27260157	HT1080	viability	GCCATCTCCGCCGCCAGGGACGG	HIF1AN	ENSG00000166135	0.129525161989051	[]	[]	1	hSpCas9	negative selection	2723826
100536005	100536028	10	-	27260157	MKN45	viability	GAGGGCTCCAGCCTCCTCCCGGG	HIF1AN	ENSG00000166135	0.21810142177524	[]	[]	5	hSpCas9	negative selection	2733014
100536517	100536540	10	-	27260157	MKN45	viability	GTACAAGAACTTGTGGGTGCTGG	HIF1AN	ENSG00000166135	-1.12878616621363	[]	[]	-8	hSpCas9	negative selection	2733953
100535943	100535966	10	+	27260157	MKN45	viability	GTCCCTGGCGGCGGAGATGGCGG	HIF1AN	ENSG00000166135	-1.38284876493362	[]	[]	-8	hSpCas9	negative selection	2734619
100536069	100536092	10	-	27260157	MKN45	viability	GACGCGGAATGGGCCTAGTCGGG	HIF1AN	ENSG00000166135	0.960983575085086	[]	[]	8	hSpCas9	negative selection	2738136
100536105	100536128	10	-	27260157	MKN45	viability	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	-0.723721168889166	[]	[]	-7	hSpCas9	negative selection	2759067
100536047	100536070	10	-	27260157	MKN45	viability	GAAGCTATAACTGCGCAACTGGG	HIF1AN	ENSG00000166135	0.362586340664099	[]	[]	6	hSpCas9	negative selection	2760433
100536414	100536437	10	-	27260157	MKN45	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	0.00853389968016307	[]	[]	0	hSpCas9	negative selection	2761783
100535964	100535987	10	+	27260157	MKN45	viability	GGCGACAGCGGCGGAGGCTGTGG	HIF1AN	ENSG00000166135	-0.81881358183076	[]	[]	-7	hSpCas9	negative selection	2763454
100536439	100536462	10	+	27260157	MKN45	viability	TTGTGTATCCTGCCCTGAAATGG	HIF1AN	ENSG00000166135	0.647683246643566	[]	[]	7	hSpCas9	negative selection	2763929
100536031	100536054	10	-	27260157	MKN45	viability	AACTGGGATTCATCCCAGGCGGG	HIF1AN	ENSG00000166135	0.548185662022939	[]	[]	7	hSpCas9	negative selection	2765859
100536447	100536470	10	-	27260157	MKN45	viability	TCAAGGTCCCATTTCAGGGCAGG	HIF1AN	ENSG00000166135	-0.395060243047497	[]	[]	-1	hSpCas9	negative selection	2766914
100536079	100536102	10	-	27260157	MKN45	viability	CTCTGACTCAGACGCGGAATGGG	HIF1AN	ENSG00000166135	-0.014522487442486	[]	[]	0	hSpCas9	negative selection	2769507
100535977	100536000	10	+	27260157	MKN45	viability	GAGGCTGTGGCCTCTGGCTCTGG	HIF1AN	ENSG00000166135	-0.455101237731792	[]	[]	-6	hSpCas9	negative selection	2772509
100535952	100535975	10	+	27260157	MKN45	viability	GGCGGAGATGGCGGCGACAGCGG	HIF1AN	ENSG00000166135	-0.325722421649989	[]	[]	-1	hSpCas9	negative selection	2773797
100535971	100535994	10	+	27260157	MKN45	viability	GCGGCGGAGGCTGTGGCCTCTGG	HIF1AN	ENSG00000166135	-1.43874415273869	[]	[]	-8	hSpCas9	negative selection	2793871
100536056	100536079	10	+	27260157	MKN45	viability	GCAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.16724883359223	[]	[]	0	hSpCas9	negative selection	2794370
100536030	100536053	10	-	27260157	MKN45	viability	ACTGGGATTCATCCCAGGCGGGG	HIF1AN	ENSG00000166135	1.23022634927833	[]	[]	9	hSpCas9	negative selection	2799924
100535941	100535964	10	-	27260157	MKN45	viability	GCCATCTCCGCCGCCAGGGACGG	HIF1AN	ENSG00000166135	-0.531237547954005	[]	[]	-6	hSpCas9	negative selection	2799956
100536005	100536028	10	-	27260157	RKO	viability	GAGGGCTCCAGCCTCCTCCCGGG	HIF1AN	ENSG00000166135	-1.00184431324697	[]	[]	-8	hSpCas9	negative selection	2809144
100536517	100536540	10	-	27260157	RKO	viability	GTACAAGAACTTGTGGGTGCTGG	HIF1AN	ENSG00000166135	-0.234529197915352	[]	[]	-1	hSpCas9	negative selection	2810083
100535943	100535966	10	+	27260157	RKO	viability	GTCCCTGGCGGCGGAGATGGCGG	HIF1AN	ENSG00000166135	-0.822499474227893	[]	[]	-7	hSpCas9	negative selection	2810749
100536069	100536092	10	-	27260157	RKO	viability	GACGCGGAATGGGCCTAGTCGGG	HIF1AN	ENSG00000166135	1.06052929335927	[]	[]	9	hSpCas9	negative selection	2814266
100536105	100536128	10	-	27260157	RKO	viability	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	-0.188588347778484	[]	[]	-1	hSpCas9	negative selection	2835197
100536047	100536070	10	-	27260157	RKO	viability	GAAGCTATAACTGCGCAACTGGG	HIF1AN	ENSG00000166135	0.319659548592443	[]	[]	1	hSpCas9	negative selection	2836563
100536414	100536437	10	-	27260157	RKO	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.314801378081116	[]	[]	-6	hSpCas9	negative selection	2837913
100535964	100535987	10	+	27260157	RKO	viability	GGCGACAGCGGCGGAGGCTGTGG	HIF1AN	ENSG00000166135	-0.474635146222068	[]	[]	-6	hSpCas9	negative selection	2839584
100536439	100536462	10	+	27260157	RKO	viability	TTGTGTATCCTGCCCTGAAATGG	HIF1AN	ENSG00000166135	0.193795004801637	[]	[]	1	hSpCas9	negative selection	2840059
100536031	100536054	10	-	27260157	RKO	viability	AACTGGGATTCATCCCAGGCGGG	HIF1AN	ENSG00000166135	0.521286233342759	[]	[]	2	hSpCas9	negative selection	2841989
100536447	100536470	10	-	27260157	RKO	viability	TCAAGGTCCCATTTCAGGGCAGG	HIF1AN	ENSG00000166135	-0.771562680882663	[]	[]	-7	hSpCas9	negative selection	2843044
100536079	100536102	10	-	27260157	RKO	viability	CTCTGACTCAGACGCGGAATGGG	HIF1AN	ENSG00000166135	0.141566908626524	[]	[]	0	hSpCas9	negative selection	2845637
100535977	100536000	10	+	27260157	RKO	viability	GAGGCTGTGGCCTCTGGCTCTGG	HIF1AN	ENSG00000166135	-0.47035864572715	[]	[]	-6	hSpCas9	negative selection	2848639
100535952	100535975	10	+	27260157	RKO	viability	GGCGGAGATGGCGGCGACAGCGG	HIF1AN	ENSG00000166135	-0.624535203509387	[]	[]	-7	hSpCas9	negative selection	2849927
100535971	100535994	10	+	27260157	RKO	viability	GCGGCGGAGGCTGTGGCCTCTGG	HIF1AN	ENSG00000166135	0.0321123247772185	[]	[]	0	hSpCas9	negative selection	2870001
100536056	100536079	10	+	27260157	RKO	viability	GCAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.146915659789001	[]	[]	0	hSpCas9	negative selection	2870500
100536030	100536053	10	-	27260157	RKO	viability	ACTGGGATTCATCCCAGGCGGGG	HIF1AN	ENSG00000166135	0.768117407218649	[]	[]	8	hSpCas9	negative selection	2876054
100535941	100535964	10	-	27260157	RKO	viability	GCCATCTCCGCCGCCAGGGACGG	HIF1AN	ENSG00000166135	0.309717282996212	[]	[]	1	hSpCas9	negative selection	2876086
100536005	100536028	10	-	27260157	SF268	viability	GAGGGCTCCAGCCTCCTCCCGGG	HIF1AN	ENSG00000166135	0.358148011910763	[]	[]	4	hSpCas9	negative selection	2885274
100536517	100536540	10	-	27260157	SF268	viability	GTACAAGAACTTGTGGGTGCTGG	HIF1AN	ENSG00000166135	-0.685465866344503	[]	[]	-5	hSpCas9	negative selection	2886213
100535943	100535966	10	+	27260157	SF268	viability	GTCCCTGGCGGCGGAGATGGCGG	HIF1AN	ENSG00000166135	-0.687388827038027	[]	[]	-5	hSpCas9	negative selection	2886879
100536069	100536092	10	-	27260157	SF268	viability	GACGCGGAATGGGCCTAGTCGGG	HIF1AN	ENSG00000166135	1.89339028691351	[]	[]	9	hSpCas9	negative selection	2890396
100536105	100536128	10	-	27260157	SF268	viability	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	-0.623150293440836	[]	[]	-5	hSpCas9	negative selection	2911327
100536047	100536070	10	-	27260157	SF268	viability	GAAGCTATAACTGCGCAACTGGG	HIF1AN	ENSG00000166135	-0.603132481798434	[]	[]	-5	hSpCas9	negative selection	2912693
100536414	100536437	10	-	27260157	SF268	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.740609233871001	[]	[]	-5	hSpCas9	negative selection	2914043
100535964	100535987	10	+	27260157	SF268	viability	GGCGACAGCGGCGGAGGCTGTGG	HIF1AN	ENSG00000166135	-0.461413823102241	[]	[]	-4	hSpCas9	negative selection	2915714
100536439	100536462	10	+	27260157	SF268	viability	TTGTGTATCCTGCCCTGAAATGG	HIF1AN	ENSG00000166135	0.0986404043066099	[]	[]	0	hSpCas9	negative selection	2916189
100536031	100536054	10	-	27260157	SF268	viability	AACTGGGATTCATCCCAGGCGGG	HIF1AN	ENSG00000166135	0.191467226313978	[]	[]	0	hSpCas9	negative selection	2918119
100536447	100536470	10	-	27260157	SF268	viability	TCAAGGTCCCATTTCAGGGCAGG	HIF1AN	ENSG00000166135	-0.85449202711515	[]	[]	-6	hSpCas9	negative selection	2919174
100536079	100536102	10	-	27260157	SF268	viability	CTCTGACTCAGACGCGGAATGGG	HIF1AN	ENSG00000166135	0.915108231756897	[]	[]	9	hSpCas9	negative selection	2921767
100535977	100536000	10	+	27260157	SF268	viability	GAGGCTGTGGCCTCTGGCTCTGG	HIF1AN	ENSG00000166135	-0.0120065780046502	[]	[]	0	hSpCas9	negative selection	2924769
100535952	100535975	10	+	27260157	SF268	viability	GGCGGAGATGGCGGCGACAGCGG	HIF1AN	ENSG00000166135	0.421541303503681	[]	[]	4	hSpCas9	negative selection	2926057
100535971	100535994	10	+	27260157	SF268	viability	GCGGCGGAGGCTGTGGCCTCTGG	HIF1AN	ENSG00000166135	-0.498711175159814	[]	[]	-4	hSpCas9	negative selection	2946131
100536056	100536079	10	+	27260157	SF268	viability	GCAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.723490366524685	[]	[]	-5	hSpCas9	negative selection	2946630
100536030	100536053	10	-	27260157	SF268	viability	ACTGGGATTCATCCCAGGCGGGG	HIF1AN	ENSG00000166135	1.17032059272628	[]	[]	9	hSpCas9	negative selection	2952184
100535941	100535964	10	-	27260157	SF268	viability	GCCATCTCCGCCGCCAGGGACGG	HIF1AN	ENSG00000166135	-0.0345298691479109	[]	[]	0	hSpCas9	negative selection	2952216
100536563	100536586	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.16241783563376713	[4,4]	[3,3]	-2	hSpCas9	positive selection	2993236
100536573	100536596	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTTAAGCCGAGGTCCAACAGGG	HIF1AN	ENSG00000166135	-0.35166906443739304	[3,3]	[2,1]	-5	hSpCas9	positive selection	2993237
100536085	100536108	10	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.5355423411856407	[3,2]	[2,0]	-7	hSpCas9	positive selection	2993238
100536091	100536114	10	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGAGTCAGAGCGACCCCCGGG	HIF1AN	ENSG00000166135	0.23886054598135759	[3,3]	[2,3]	5	hSpCas9	positive selection	2993239
100536563	100536586	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.10295273426008061	[4,4]	[5,2]	1	hSpCas9	positive selection	3061094
100536573	100536596	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTTAAGCCGAGGTCCAACAGGG	HIF1AN	ENSG00000166135	-0.2287380925014623	[3,3]	[1,2]	-3	hSpCas9	positive selection	3061095
100536085	100536108	10	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.5258941851796939	[3,3]	[0,1]	-7	hSpCas9	positive selection	3061096
100536091	100536114	10	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGAGTCAGAGCGACCCCCGGG	HIF1AN	ENSG00000166135	0.3687466711691987	[3,3]	[2,2]	6	hSpCas9	positive selection	3061097
100545015	100545038		+	24336571	A375	resistance to PLX after 7 days	ACGATGCATCTTATTCCCTCCGG	HIF1AN	ENSG00000166135	-0.16951071947736268	[19,15]	[14,16]	-5	hSpCas9	positive selection	3119005
100545959	100545982		-	24336571	A375	resistance to PLX after 7 days	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.07896660275025852	[10,8]	[10,10]	2	hSpCas9	positive selection	3119006
100545950	100545973		+	24336571	A375	resistance to PLX after 7 days	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.06725720910976074	[7,6]	[7,5]	-2	hSpCas9	positive selection	3119008
100545015	100545038		+	24336571	A375	resistance to PLX after 14 days	ACGATGCATCTTATTCCCTCCGG	HIF1AN	ENSG00000166135	1.1253634706275477	[13,13]	[20,6]	8	hSpCas9	positive selection	3176798
100545959	100545982		-	24336571	A375	resistance to PLX after 14 days	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.4650338863108896	[6,8]	[4,4]	4	hSpCas9	positive selection	3176799
100545950	100545973		+	24336571	A375	resistance to PLX after 14 days	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	0.45998951720946735	[9,2]	[3,2]	4	hSpCas9	positive selection	3176801
100545015	100545038		+	24336571	A375	viability after 7 days	ACGATGCATCTTATTCCCTCCGG	HIF1AN	ENSG00000166135	-0.24759684046578956	[22]	[19,15]	-4	hSpCas9	negative selection	3234591
100545959	100545982		-	24336571	A375	viability after 7 days	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.09082680977123886	[9]	[10,8]	1	hSpCas9	negative selection	3234592
100545950	100545973		+	24336571	A375	viability after 7 days	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5824981207726798	[11]	[7,6]	-7	hSpCas9	negative selection	3234594
100545015	100545038		+	24336571	A375	viability after 14 days	ACGATGCATCTTATTCCCTCCGG	HIF1AN	ENSG00000166135	-0.6157540856580107	[22]	[13,13]	-6	hSpCas9	negative selection	3292384
100545959	100545982		-	24336571	A375	viability after 14 days	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.17767599324513894	[9]	[6,8]	-2	hSpCas9	negative selection	3292385
100545950	100545973		+	24336571	A375	viability after 14 days	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.8054610298699143	[11]	[9,2]	-7	hSpCas9	negative selection	3292387
100545950	100545973	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	0.1710425243607608	[118,152]	[0,0]	0	hSpCas9	positive selection	3353378
100545959	100545982	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.2931942510816786	[182,191]	[0,0]	-2	hSpCas9	positive selection	3353379
100540646	100540669	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.0584238172833234	[134,158]	[0,0]	0	hSpCas9	positive selection	3353380
100536414	100536437	10	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-1.3720304086337745	[395,395]	[0,0]	-8	hSpCas9	positive selection	3372579
100536562	100536585	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	2.169863370195496	[33,33]	[0,0]	7	hSpCas9	positive selection	3372580
100540706	100540729	10	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	-0.47059424311736403	[211,211]	[0,0]	-3	hSpCas9	positive selection	3372581
100536562	100536585	10	+	26780180	HT29	viability (Avana library 4 designs)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.334522945042163	[]	[]	1	hSpCas9	negative selection	3430497
100536572	100536595	10	+	26780180	HT29	viability (Avana library 4 designs)	CTTTAAGCCGAGGTCCAACAGGG	HIF1AN	ENSG00000166135	0.678717369541398	[]	[]	2	hSpCas9	negative selection	3430498
100536085	100536108	10	-	26780180	HT29	viability (Avana library 4 designs)	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	2.44869421358348	[]	[]	8	hSpCas9	negative selection	3430499
100536090	100536113	10	+	26780180	HT29	viability (Avana library 4 designs)	TCTGAGTCAGAGCGACCCCCGGG	HIF1AN	ENSG00000166135	1.25947966666979	[]	[]	5	hSpCas9	negative selection	3430500
100536085	100536108	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.905409901535227	[]	[]	1	hSpCas9	negative selection	3515689
100536562	100536585	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	3.16345980271673	[]	[]	5	hSpCas9	negative selection	3515690
100536572	100536595	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTTAAGCCGAGGTCCAACAGGG	HIF1AN	ENSG00000166135	1.11298328997397	[]	[]	1	hSpCas9	negative selection	3515691
100536090	100536113	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGAGTCAGAGCGACCCCCGGG	HIF1AN	ENSG00000166135	-1.61403695822433	[]	[]	-2	hSpCas9	negative selection	3515692
100536105	100536128	10	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	-2.12208518438605	[]	[]	-3	hSpCas9	negative selection	3515693
100536632	100536655	10	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGATATACAGCAGCGAGGAGGGG	HIF1AN	ENSG00000166135	2.27978273980602	[]	[]	3	hSpCas9	negative selection	3515694
100536085	100536108	10	-	26780180	A375	viability (Avana lentiGuide)	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	7.12025239508135	[]	[]	5	hSpCas9	negative selection	3624348
100536562	100536585	10	+	26780180	A375	viability (Avana lentiGuide)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	2.11255754419251	[]	[]	2	hSpCas9	negative selection	3624349
100536572	100536595	10	+	26780180	A375	viability (Avana lentiGuide)	CTTTAAGCCGAGGTCCAACAGGG	HIF1AN	ENSG00000166135	4.68613800691213	[]	[]	4	hSpCas9	negative selection	3624350
100536090	100536113	10	+	26780180	A375	viability (Avana lentiGuide)	TCTGAGTCAGAGCGACCCCCGGG	HIF1AN	ENSG00000166135	0.0309451488910085	[]	[]	0	hSpCas9	negative selection	3624351
100536105	100536128	10	-	26780180	A375	viability (Avana lentiGuide)	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	3.78629506554196	[]	[]	3	hSpCas9	negative selection	3624352
100536632	100536655	10	+	26780180	A375	viability (Avana lentiGuide)	GGATATACAGCAGCGAGGAGGGG	HIF1AN	ENSG00000166135	3.52008111455917	[]	[]	3	hSpCas9	negative selection	3624353
100536085	100536108	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.18889211014880966	[4]	[4,2]	-3	hSpCas9	positive selection	3733007
100536562	100536585	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.12563934946052113	[6]	[6,6]	3	hSpCas9	positive selection	3733008
100536572	100536595	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTTAAGCCGAGGTCCAACAGGG	HIF1AN	ENSG00000166135	-0.02145463529345093	[4]	[4,4]	0	hSpCas9	positive selection	3733009
100536090	100536113	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGAGTCAGAGCGACCCCCGGG	HIF1AN	ENSG00000166135	0.00047436055043319214	[4]	[5,3]	0	hSpCas9	positive selection	3733010
100536105	100536128	10	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	0.1715612936344015	[4]	[5,5]	4	hSpCas9	positive selection	3733011
100536632	100536655	10	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATATACAGCAGCGAGGAGGGG	HIF1AN	ENSG00000166135	0.23779305073006785	[4]	[5,4]	6	hSpCas9	positive selection	3733012
100536085	100536108	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.23670304817755525	[4]	[3,3]	-3	hSpCas9	positive selection	3841614
100536562	100536585	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.0824032899933888	[6]	[6,5]	1	hSpCas9	positive selection	3841615
100536572	100536595	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTTAAGCCGAGGTCCAACAGGG	HIF1AN	ENSG00000166135	0.10003043026421864	[5]	[4,4]	2	hSpCas9	positive selection	3841616
100536090	100536113	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGAGTCAGAGCGACCCCCGGG	HIF1AN	ENSG00000166135	0.09701149787705435	[5]	[5,3]	2	hSpCas9	positive selection	3841617
100536105	100536128	10	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAATAAGCTCCTCTGCCCGGGGG	HIF1AN	ENSG00000166135	0.19643116412555256	[5]	[5,4]	5	hSpCas9	positive selection	3841618
100536632	100536655	10	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATATACAGCAGCGAGGAGGGG	HIF1AN	ENSG00000166135	-0.35847407621782823	[5]	[4,2]	-5	hSpCas9	positive selection	3841619
100545959	100545982	10	-	26780180	A375	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	1.06387457255745	[]	[]	5	hSpCas9	negative selection	3947676
100536562	100536585	10	+	26780180	A375	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.592379376838587	[]	[]	1	hSpCas9	negative selection	3947677
100540706	100540729	10	+	26780180	A375	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	1.79999954734222	[]	[]	9	hSpCas9	negative selection	3947678
100540646	100540669	10	+	26780180	A375	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	1.35951134541503	[]	[]	7	hSpCas9	negative selection	3947679
100545950	100545973	10	+	26780180	A375	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	1.71690007163972	[]	[]	9	hSpCas9	negative selection	3947680
100536414	100536437	10	-	26780180	A375	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	2.18564865725976	[]	[]	9	hSpCas9	negative selection	3947681
100545959	100545982	10	-	26780180	HT29	viability (GeCKOv2 library)	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	1.34034257054731	[]	[]	6	hSpCas9	negative selection	4055642
100536562	100536585	10	+	26780180	HT29	viability (GeCKOv2 library)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.691744701063524	[]	[]	2	hSpCas9	negative selection	4055643
100540706	100540729	10	+	26780180	HT29	viability (GeCKOv2 library)	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	1.35652515656573	[]	[]	7	hSpCas9	negative selection	4055644
100540646	100540669	10	+	26780180	HT29	viability (GeCKOv2 library)	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.0519848132531226	[]	[]	-1	hSpCas9	negative selection	4055645
100545950	100545973	10	+	26780180	HT29	viability (GeCKOv2 library)	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	0.568155143512858	[]	[]	2	hSpCas9	negative selection	4055646
100536414	100536437	10	-	26780180	HT29	viability (GeCKOv2 library)	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	1.33850735777011	[]	[]	6	hSpCas9	negative selection	4055647
100545015	100545038	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACGATGCATCTTATTCCCTCCGG	HIF1AN	ENSG00000166135	0.11221264269967623	[3]	[2,3]	3	hSpCas9	positive selection	4142483
100545959	100545982	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.055479184103871176	[3]	[1,2]	-1	hSpCas9	positive selection	4142484
100545950	100545973	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	0.12961307118061927	[2]	[1,1]	3	hSpCas9	positive selection	4142486
100529438	100529461	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.05116360641049167	[2]	[1,1]	1	hSpCas9	positive selection	4154789
100529386	100529409	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.28585820263254746	[3]	[1,1]	-6	hSpCas9	positive selection	4154791
100545015	100545038	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACGATGCATCTTATTCCCTCCGG	HIF1AN	ENSG00000166135	0.0415011980886959	[4]	[1,0,5,0]	0	hSpCas9	positive selection	4206505
100545959	100545982	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.2595517147556431	[3]	[0,3,0,0]	-4	hSpCas9	positive selection	4206506
100545950	100545973	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	0.8104522270580812	[2]	[0,0,0,3]	5	hSpCas9	positive selection	4206508
100529438	100529461	10	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.11203475858100975	[1]	[0,0,0,0]	-2	hSpCas9	positive selection	4218811
100529386	100529409	10	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.2615983697576264	[3]	[0,1,1,0]	-4	hSpCas9	positive selection	4218813
100545950	100545973	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.0574958424746172	[4]	[3,2]	-1	hSpCas9	positive selection	4274979
100545959	100545982	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.31139005269984965	[3]	[3,1]	-6	hSpCas9	positive selection	4274980
100540646	100540669	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.36978476792274395	[3]	[3,2]	7	hSpCas9	positive selection	4274981
100529386	100529409	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.05139785750858805	[3]	[3,2]	-1	hSpCas9	positive selection	4285185
100536414	100536437	10	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	0.10682955481586764	[4]	[3,3]	2	hSpCas9	positive selection	4339240
100536562	100536585	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.06074583798207822	[1]	[1,0]	1	hSpCas9	positive selection	4339241
100540706	100540729	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	-0.30604531782368044	[2]	[1,1]	-6	hSpCas9	positive selection	4339242
100529438	100529461	10	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.040363358802871785	[1]	[2,0]	-1	hSpCas9	positive selection	4349445
100536057	100536079	10	+	27760321	OCIAML3	viability	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.9850179509222569	[833,737]	[329,283]	-7	hSpCas9	negative selection	4406879
100536085	100536107	10	-	27760321	OCIAML3	viability	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-1.1354014137472246	[697,636]	[240,232]	-7	hSpCas9	negative selection	4406880
100536572	100536594	10	+	27760321	OCIAML3	viability	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	-0.4955035693230909	[428,380]	[176,285]	-5	hSpCas9	negative selection	4406881
100536628	100536650	10	+	27760321	OCIAML3	viability	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.40379296984017043	[550,340]	[225,302]	-4	hSpCas9	negative selection	4406882
100540647	100540669	10	+	27760321	OCIAML3	viability	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.4909773487858352	[593,434]	[346,200]	-5	hSpCas9	negative selection	4406883
100536057	100536079	10	+	27760321	OCIAML2	viability	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.8729341874338118	[833,737]	[280,432]	-7	hSpCas9	negative selection	4490342
100536085	100536107	10	-	27760321	OCIAML2	viability	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-1.0634770808191187	[697,636]	[221,305]	-7	hSpCas9	negative selection	4490343
100536572	100536594	10	+	27760321	OCIAML2	viability	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	-0.09917163057547104	[428,380]	[332,268]	-1	hSpCas9	negative selection	4490344
100536628	100536650	10	+	27760321	OCIAML2	viability	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.1646415931904506	[550,340]	[273,372]	-2	hSpCas9	negative selection	4490345
100540647	100540669	10	+	27760321	OCIAML2	viability	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.25532588534842293	[593,434]	[262,453]	-3	hSpCas9	negative selection	4490346
100536057	100536079	10	+	27760321	MV411	viability	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-1.051881569810764	[833,737]	[186,343]	-6	hSpCas9	negative selection	4573805
100536085	100536107	10	-	27760321	MV411	viability	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.21442614667463095	[697,636]	[464,250]	-1	hSpCas9	negative selection	4573806
100536572	100536594	10	+	27760321	MV411	viability	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	-0.03549118305771959	[428,380]	[203,344]	0	hSpCas9	negative selection	4573807
100536628	100536650	10	+	27760321	MV411	viability	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.2499016970404122	[550,340]	[165,359]	-2	hSpCas9	negative selection	4573808
100540647	100540669	10	+	27760321	MV411	viability	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.13546781677204017	[593,434]	[286,334]	-1	hSpCas9	negative selection	4573809
100536057	100536079	10	+	27760321	HL60	viability	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.3250831064947254	[833,737]	[532,488]	-4	hSpCas9	negative selection	4657268
100536085	100536107	10	-	27760321	HL60	viability	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.5780605261358871	[697,636]	[717,914]	7	hSpCas9	negative selection	4657269
100536572	100536594	10	+	27760321	HL60	viability	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	-0.0708196389575679	[428,380]	[280,349]	-1	hSpCas9	negative selection	4657270
100536628	100536650	10	+	27760321	HL60	viability	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	0.16614628669302997	[550,340]	[492,305]	2	hSpCas9	negative selection	4657271
100540647	100540669	10	+	27760321	HL60	viability	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.2592398246024625	[593,434]	[309,387]	-3	hSpCas9	negative selection	4657272
100536057	100536079	10	+	27760321	HT1080	viability	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	0.006658743188464489	[737,575]	[208,321]	0	hSpCas9	negative selection	4740731
100536085	100536107	10	-	27760321	HT1080	viability	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.8059797614715934	[636,496]	[181,627]	4	hSpCas9	negative selection	4740732
100536572	100536594	10	+	27760321	HT1080	viability	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	-0.018401912381547203	[380,297]	[102,166]	0	hSpCas9	negative selection	4740733
100536628	100536650	10	+	27760321	HT1080	viability	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	2.2143647610400206	[340,265]	[783,316]	9	hSpCas9	negative selection	4740734
100540647	100540669	10	+	27760321	HT1080	viability	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.5846430830372193	[434,339]	[231,230]	3	hSpCas9	negative selection	4740735
100536057	100536079	10	+	27760321	HT29	viability after 7 days	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.37059123855106707	[737,575]	[487,744,700]	-5	hSpCas9	negative selection	4824194
100536085	100536107	10	-	27760321	HT29	viability after 7 days	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.37917966126575564	[636,496]	[858,454,413]	-5	hSpCas9	negative selection	4824195
100536572	100536594	10	+	27760321	HT29	viability after 7 days	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.06859448500472368	[380,297]	[353,514,487]	1	hSpCas9	negative selection	4824196
100536628	100536650	10	+	27760321	HT29	viability after 7 days	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	0.6056879383848198	[340,265]	[774,618,417]	8	hSpCas9	negative selection	4824197
100540647	100540669	10	+	27760321	HT29	viability after 7 days	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.4160314828831378	[434,339]	[784,732,497]	6	hSpCas9	negative selection	4824198
100536057	100536079	10	+	27760321	HT29	viability after 25 days	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.3157821522903884	[737,575]	[600,560,651]	-3	hSpCas9	negative selection	4907657
100536085	100536107	10	-	27760321	HT29	viability after 25 days	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.026639099210242212	[636,496]	[733,618,616]	0	hSpCas9	negative selection	4907658
100536572	100536594	10	+	27760321	HT29	viability after 25 days	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.30880055170780896	[380,297]	[471,426,549]	3	hSpCas9	negative selection	4907659
100536628	100536650	10	+	27760321	HT29	viability after 25 days	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	1.454882888674052	[340,265]	[870,740,1277]	9	hSpCas9	negative selection	4907660
100540647	100540669	10	+	27760321	HT29	viability after 25 days	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.7626901308736651	[434,339]	[603,944,708]	8	hSpCas9	negative selection	4907661
100536057	100536079	10	+	27760321	HT29	viability after 22 days	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.053194510833826536	[737,575]	[736,823,633]	0	hSpCas9	negative selection	4991120
100536085	100536107	10	-	27760321	HT29	viability after 22 days	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.044946888874412894	[636,496]	[854,526,516]	0	hSpCas9	negative selection	4991121
100536572	100536594	10	+	27760321	HT29	viability after 22 days	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.5326707342828078	[380,297]	[672,631,393]	6	hSpCas9	negative selection	4991122
100536628	100536650	10	+	27760321	HT29	viability after 22 days	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	1.254072364360459	[340,265]	[781,675,1055]	9	hSpCas9	negative selection	4991123
100540647	100540669	10	+	27760321	HT29	viability after 22 days	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.748576310292321	[434,339]	[617,865,777]	8	hSpCas9	negative selection	4991124
100536057	100536079	10	+	27760321	HT29	viability after 19 days	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	0.22397723743733766	[737,575]	[917,1070,655]	2	hSpCas9	negative selection	5074583
100536085	100536107	10	-	27760321	HT29	viability after 19 days	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.0746713318014035	[636,496]	[971,329,772]	0	hSpCas9	negative selection	5074584
100536572	100536594	10	+	27760321	HT29	viability after 19 days	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.12094472147740834	[380,297]	[723,495,90]	1	hSpCas9	negative selection	5074585
100536628	100536650	10	+	27760321	HT29	viability after 19 days	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	1.4462924610009347	[340,265]	[1067,655,1118]	9	hSpCas9	negative selection	5074586
100540647	100540669	10	+	27760321	HT29	viability after 19 days	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	1.4658071305643887	[434,339]	[971,1489,1184]	9	hSpCas9	negative selection	5074587
100536057	100536079	10	+	27760321	HT29	viability after 16 days	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.12715594537754182	[737,575]	[629,632,752]	-1	hSpCas9	negative selection	5158046
100536085	100536107	10	-	27760321	HT29	viability after 16 days	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.058454065352460005	[636,496]	[811,476,560]	0	hSpCas9	negative selection	5158047
100536572	100536594	10	+	27760321	HT29	viability after 16 days	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.2644738197802594	[380,297]	[455,641,265]	3	hSpCas9	negative selection	5158048
100536628	100536650	10	+	27760321	HT29	viability after 16 days	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	0.9795825001196278	[340,265]	[767,471,782]	9	hSpCas9	negative selection	5158049
100540647	100540669	10	+	27760321	HT29	viability after 16 days	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.8133602801733448	[434,339]	[623,1091,547]	8	hSpCas9	negative selection	5158050
100536057	100536079	10	+	27760321	HT29	viability after 13 days	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.28950103070180133	[737,575]	[516,798,558]	-4	hSpCas9	negative selection	5241509
100536085	100536107	10	-	27760321	HT29	viability after 13 days	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.14681181670191057	[636,496]	[740,345,688]	-2	hSpCas9	negative selection	5241510
100536572	100536594	10	+	27760321	HT29	viability after 13 days	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.2578857276774492	[380,297]	[383,623,408]	3	hSpCas9	negative selection	5241511
100536628	100536650	10	+	27760321	HT29	viability after 13 days	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	0.8460872275001722	[340,265]	[729,477,686]	9	hSpCas9	negative selection	5241512
100540647	100540669	10	+	27760321	HT29	viability after 13 days	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.8124000525111628	[434,339]	[751,1124,508]	9	hSpCas9	negative selection	5241513
100536057	100536079	10	+	27760321	HT29	viability after 10 days	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	-0.3989745872117091	[737,575]	[598,807,467]	-5	hSpCas9	negative selection	5324972
100536085	100536107	10	-	27760321	HT29	viability after 10 days	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.2650769034160295	[636,496]	[765,808,972]	3	hSpCas9	negative selection	5324973
100536572	100536594	10	+	27760321	HT29	viability after 10 days	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.17539179016336795	[380,297]	[524,474,436]	2	hSpCas9	negative selection	5324974
100536628	100536650	10	+	27760321	HT29	viability after 10 days	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	1.2645345593525181	[340,265]	[659,1243,837]	9	hSpCas9	negative selection	5324975
100540647	100540669	10	+	27760321	HT29	viability after 10 days	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.7723288995930145	[434,339]	[900,688,883]	9	hSpCas9	negative selection	5324976
100536057	100536079	10	+	27760321	MOLM13	viability	CAGTTATAGCTTCCCGACTAGG	HIF1AN	ENSG00000166135	0.2165188411707435	[833,737]	[1006,94]	1	hSpCas9	negative selection	5408435
100536085	100536107	10	-	27760321	MOLM13	viability	GGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.5282945117209441	[697,636]	[920,220]	3	hSpCas9	negative selection	5408436
100536572	100536594	10	+	27760321	MOLM13	viability	CTTTAAGCCGAGGTCCAACAGG	HIF1AN	ENSG00000166135	0.3081513166795549	[428,380]	[477,115]	2	hSpCas9	negative selection	5408437
100536628	100536650	10	+	27760321	MOLM13	viability	TGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.23883065970485104	[550,340]	[413,35]	-2	hSpCas9	negative selection	5408438
100540647	100540669	10	+	27760321	MOLM13	viability	CAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.007810441276766306	[593,434]	[253,318]	0	hSpCas9	negative selection	5408439
100535928	100535951	10	+	27661255	K562	viability	GTTCCGGTGGGGGCCGTCCCTGG	HIF1AN	ENSG00000166135	-0.37190694440745875	[909,955]	[623,533]	-7	dCas9-KRAB	negative selection	5484632
100536145	100536168	10	+	27661255	K562	viability	GGGGCCGCGTCTAAAGGGAGAGG	HIF1AN	ENSG00000166135	-0.014184602628772247	[557,752]	[593,448]	0	dCas9-KRAB	negative selection	5484633
100536338	100536361	10	+	27661255	K562	viability	GATCATGGAGGCCAACCCACCGG	HIF1AN	ENSG00000166135	-0.06038878583069185	[1458,1498]	[1200,1073]	-2	dCas9-KRAB	negative selection	5484634
100535941	100535964	10	-	27661255	K562	viability	GCCATCTCCGCCGCCAGGGACGG	HIF1AN	ENSG00000166135	-1.8091856114058409	[171,201]	[55,30]	-9	dCas9-KRAB	negative selection	5484635
100536085	100536108	10	-	27661255	K562	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.31338712067103036	[446,701]	[650,492]	8	dCas9-KRAB	negative selection	5484636
100529763	100529786	10	+	27661255	K562	viability	GGACCTGTCCGTGCGCCCAGCGG	HIF1AN	ENSG00000166135	-1.4040429319674887	[1972,2125]	[667,574]	-9	dCas9-KRAB	negative selection	5496039
100529777	100529800	10	+	27661255	K562	viability	GCCCAGCGGCATCACGTTCCGGG	HIF1AN	ENSG00000166135	-0.8255794250320705	[955,927]	[521,341]	-8	dCas9-KRAB	negative selection	5496040
100529365	100529388	10	-	27661255	K562	viability	GGCATGGGGTGAGACAGAGAGGG	HIF1AN	ENSG00000166135	-0.7793219820653398	[2501,2398]	[1156,1127]	-8	dCas9-KRAB	negative selection	5496041
100529552	100529575	10	-	27661255	K562	viability	GCGACTTGAAGCCTTCGGAGCGG	HIF1AN	ENSG00000166135	-1.4674808708203786	[231,195]	[88,38]	-9	dCas9-KRAB	negative selection	5496042
100529663	100529686	10	-	27661255	K562	viability	GCGGCGGCAGCCTCCGGGTAGGG	HIF1AN	ENSG00000166135	-1.1554526614072678	[1630,1393]	[659,444]	-8	dCas9-KRAB	negative selection	5496043
100529763	100529786	10	+	27661255	K562	viability	GGACCTGTCCGTGCGCCCAGCGG	HIF1AN	ENSG00000166135	-1.4040429319674887	[1972,2125]	[667,574]	-9	dCas9-KRAB	negative selection	5509903
100529777	100529800	10	+	27661255	K562	viability	GCCCAGCGGCATCACGTTCCGGG	HIF1AN	ENSG00000166135	-0.8255794250320705	[955,927]	[521,341]	-8	dCas9-KRAB	negative selection	5509904
100529365	100529388	10	-	27661255	K562	viability	GGCATGGGGTGAGACAGAGAGGG	HIF1AN	ENSG00000166135	-0.7793219820653398	[2501,2398]	[1156,1127]	-8	dCas9-KRAB	negative selection	5509905
100529552	100529575	10	-	27661255	K562	viability	GCGACTTGAAGCCTTCGGAGCGG	HIF1AN	ENSG00000166135	-1.4674808708203786	[231,195]	[88,38]	-9	dCas9-KRAB	negative selection	5509906
100529663	100529686	10	-	27661255	K562	viability	GCGGCGGCAGCCTCCGGGTAGGG	HIF1AN	ENSG00000166135	-1.1554526614072678	[1630,1393]	[659,444]	-8	dCas9-KRAB	negative selection	5509907
100529857	100529880	10	-	27661255	K562	viability	GCAGAAGGGAAACGTGAAGAAGG	HIF1AN	ENSG00000166135	-0.7705990261336161	[700,674]	[330,314]	-8	dCas9-KRAB	negative selection	5509908
100545950	100545973	10	+	27260156	BXPC3	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.32737592976923247	[993]	[714,726,976,920]	-6	hSpCas9	negative selection	5547439
100545959	100545982	10	-	27260156	BXPC3	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.08248527607746059	[759]	[750,840,815,977]	1	hSpCas9	negative selection	5547440
100540646	100540669	10	+	27260156	BXPC3	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.006140206673165977	[549]	[469,627,560,643]	0	hSpCas9	negative selection	5547441
100529386	100529409	10	-	27260156	BXPC3	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.5719386230857925	[813]	[493,525,549,748]	-8	hSpCas9	negative selection	5557645
100536414	100536437	10	-	27260156	BXPC3	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.11371048133961281	[1365]	[1258,1265,1359,1406]	-3	hSpCas9	negative selection	5611700
100536562	100536585	10	+	27260156	BXPC3	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.5408699890780999	[139]	[174,181,177,335]	9	hSpCas9	negative selection	5611701
100540706	100540729	10	+	27260156	BXPC3	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.4495353572725109	[418]	[614,449,596,752]	8	hSpCas9	negative selection	5611702
100529438	100529461	10	+	27260156	BXPC3	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.057257940324868084	[110]	[115,111,154,97]	1	hSpCas9	negative selection	5621905
100545950	100545973	10	+	27260156	A673	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.3699669922530554	[993]	[1154,995,771,787]	-7	hSpCas9	negative selection	5668690
100545959	100545982	10	-	27260156	A673	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.09620107804602385	[759]	[937,856,765,862]	-2	hSpCas9	negative selection	5668691
100540646	100540669	10	+	27260156	A673	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.21432780990828845	[549]	[835,736,707,792]	5	hSpCas9	negative selection	5668692
100529386	100529409	10	-	27260156	A673	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.22061665233045458	[813]	[938,831,872,713]	-5	hSpCas9	negative selection	5678896
100536414	100536437	10	-	27260156	A673	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.20033923365694917	[1365]	[1552,1407,1423,1331]	-5	hSpCas9	negative selection	5732951
100536562	100536585	10	+	27260156	A673	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.6684110740760751	[139]	[252,316,250,242]	9	hSpCas9	negative selection	5732952
100540706	100540729	10	+	27260156	A673	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.14907705347785727	[418]	[561,521,523,627]	3	hSpCas9	negative selection	5732953
100529438	100529461	10	+	27260156	A673	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.02094111340677962	[110]	[141,118,129,135]	0	hSpCas9	negative selection	5743156
100545950	100545973	10	+	27260156	A375	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5793627189282351	[993]	[757,857,823,686]	-7	hSpCas9	negative selection	5789941
100545959	100545982	10	-	27260156	A375	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.05352070123937103	[759]	[989,783,861,781]	-1	hSpCas9	negative selection	5789942
100540646	100540669	10	+	27260156	A375	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.14500541317611723	[549]	[569,607,609,541]	-2	hSpCas9	negative selection	5789943
100529386	100529409	10	-	27260156	A375	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.36621934334477674	[813]	[678,639,982,642]	-5	hSpCas9	negative selection	5800147
100536414	100536437	10	-	27260156	A375	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.3504176961641676	[1365]	[1053,1655,1217,1140]	-5	hSpCas9	negative selection	5854202
100536562	100536585	10	+	27260156	A375	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.3925012124024976	[139]	[308,147,175,215]	6	hSpCas9	negative selection	5854203
100540706	100540729	10	+	27260156	A375	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.2806100950436778	[418]	[500,709,613,568]	4	hSpCas9	negative selection	5854204
100529438	100529461	10	+	27260156	A375	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.2831857809134457	[110]	[151,299,84,117]	4	hSpCas9	negative selection	5864407
100545950	100545973	10	+	27260156	COLO741	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.3353289672316092	[993]	[1204,946,890]	-6	hSpCas9	negative selection	5911192
100545959	100545982	10	-	27260156	COLO741	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.12442848175204224	[759]	[1071,841,779]	-3	hSpCas9	negative selection	5911193
100540646	100540669	10	+	27260156	COLO741	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.38243102291963593	[549]	[887,956,899]	7	hSpCas9	negative selection	5911194
100529386	100529409	10	-	27260156	COLO741	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.08412386712984521	[813]	[947,932,1051]	-2	hSpCas9	negative selection	5921398
100536414	100536437	10	-	27260156	COLO741	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	0.30369215981386777	[1365]	[3935,1568,1175]	6	hSpCas9	negative selection	5975453
100536562	100536585	10	+	27260156	COLO741	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.5226498671000572	[139]	[299,259,216]	9	hSpCas9	negative selection	5975454
100540706	100540729	10	+	27260156	COLO741	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.10963817654387467	[418]	[620,547,566]	2	hSpCas9	negative selection	5975455
100529438	100529461	10	+	27260156	COLO741	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.011076730181267092	[110]	[207,113,107]	0	hSpCas9	negative selection	5985658
100545950	100545973	10	+	27260156	CAL120	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5611714934887528	[993]	[728,864,902]	-7	hSpCas9	negative selection	6032443
100545959	100545982	10	-	27260156	CAL120	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.2484885362457525	[759]	[1109,1134,1122]	4	hSpCas9	negative selection	6032444
100540646	100540669	10	+	27260156	CAL120	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.16878585711973218	[549]	[806,657,846]	2	hSpCas9	negative selection	6032445
100529386	100529409	10	-	27260156	CAL120	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.40577668755098933	[813]	[884,685,740]	-5	hSpCas9	negative selection	6042649
100536414	100536437	10	-	27260156	CAL120	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.3481003279786321	[1365]	[1354,1281,1370]	-5	hSpCas9	negative selection	6096704
100536562	100536585	10	+	27260156	CAL120	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.451276224669781	[139]	[153,263,282]	6	hSpCas9	negative selection	6096705
100540706	100540729	10	+	27260156	CAL120	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.054209923636105925	[418]	[809,408,446]	0	hSpCas9	negative selection	6096706
100529438	100529461	10	+	27260156	CAL120	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.391847929919499	[110]	[370,121,80]	6	hSpCas9	negative selection	6106909
100545950	100545973	10	+	27260156	CADOES1	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5795519043930766	[993]	[476,736,645,614]	-8	hSpCas9	negative selection	6153694
100545959	100545982	10	-	27260156	CADOES1	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.3824124891799315	[759]	[460,556,589,561]	-6	hSpCas9	negative selection	6153695
100540646	100540669	10	+	27260156	CADOES1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.2740231947791073	[549]	[366,523,391,408]	-5	hSpCas9	negative selection	6153696
100529386	100529409	10	-	27260156	CADOES1	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.4333073081429767	[813]	[557,464,770,443]	-6	hSpCas9	negative selection	6163900
100536414	100536437	10	-	27260156	CADOES1	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.3465304908833897	[1365]	[814,1204,968,1008]	-6	hSpCas9	negative selection	6217955
100536562	100536585	10	+	27260156	CADOES1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.09890415234178684	[139]	[141,83,157,174]	1	hSpCas9	negative selection	6217956
100540706	100540729	10	+	27260156	CADOES1	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.3094781221322289	[418]	[588,377,461,502]	5	hSpCas9	negative selection	6217957
100529438	100529461	10	+	27260156	CADOES1	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.21274944086229297	[110]	[198,89,102,84]	3	hSpCas9	negative selection	6228160
100545950	100545973	10	+	27260156	EWS502	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5533919580366411	[993]	[704,573,742,862]	-7	hSpCas9	negative selection	6274945
100545959	100545982	10	-	27260156	EWS502	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.10176328820379066	[759]	[654,621,858,889]	-2	hSpCas9	negative selection	6274946
100540646	100540669	10	+	27260156	EWS502	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.3827488627044837	[549]	[742,573,789,951]	6	hSpCas9	negative selection	6274947
100529386	100529409	10	-	27260156	EWS502	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.6362951287612277	[813]	[437,511,648,640]	-7	hSpCas9	negative selection	6285151
100536414	100536437	10	-	27260156	EWS502	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.0937050033688609	[1365]	[1301,1463,1111,1552]	-2	hSpCas9	negative selection	6339206
100536562	100536585	10	+	27260156	EWS502	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.1672459050654307	[139]	[100,164,101,163]	-3	hSpCas9	negative selection	6339207
100540706	100540729	10	+	27260156	EWS502	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.1465968879374935	[418]	[502,545,505,397]	2	hSpCas9	negative selection	6339208
100529438	100529461	10	+	27260156	EWS502	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.40138962509758835	[110]	[210,173,84,140]	7	hSpCas9	negative selection	6349411
100545950	100545973	10	+	27260156	EW8	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.6269701330246537	[993]	[570,480,432,619]	-8	hSpCas9	negative selection	6396196
100545959	100545982	10	-	27260156	EW8	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.10807954904402539	[759]	[574,530,590,583]	-2	hSpCas9	negative selection	6396197
100540646	100540669	10	+	27260156	EW8	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.23016308504539792	[549]	[725,520,454,421]	4	hSpCas9	negative selection	6396198
100529386	100529409	10	-	27260156	EW8	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.5323804006690145	[813]	[545,506,483,291]	-7	hSpCas9	negative selection	6406402
100536414	100536437	10	-	27260156	EW8	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.24243287155993576	[1365]	[1073,806,947,923]	-4	hSpCas9	negative selection	6460457
100536562	100536585	10	+	27260156	EW8	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.46478472982233	[139]	[192,187,133,118]	8	hSpCas9	negative selection	6460458
100540706	100540729	10	+	27260156	EW8	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.10853117760529273	[418]	[479,320,268,421]	2	hSpCas9	negative selection	6460459
100529438	100529461	10	+	27260156	EW8	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.029831050779737023	[110]	[75,79,62,150]	0	hSpCas9	negative selection	6470662
100545950	100545973	10	+	27260156	CORL105	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.33492678436569434	[993]	[625,947,1383,793]	-6	hSpCas9	negative selection	6517447
100545959	100545982	10	-	27260156	CORL105	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.04937058568011943	[759]	[741,1055,1098,804]	0	hSpCas9	negative selection	6517448
100540646	100540669	10	+	27260156	CORL105	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.29486345570852646	[549]	[848,628,920,785]	5	hSpCas9	negative selection	6517449
100529386	100529409	10	-	27260156	CORL105	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.5761413056698542	[813]	[521,492,974,617]	-8	hSpCas9	negative selection	6527653
100536414	100536437	10	-	27260156	CORL105	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.2956973737899531	[1365]	[1356,1200,1512,1176]	-5	hSpCas9	negative selection	6581708
100536562	100536585	10	+	27260156	CORL105	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.15187430343503783	[139]	[134,201,230,165]	3	hSpCas9	negative selection	6581709
100540706	100540729	10	+	27260156	CORL105	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.2500693781880797	[418]	[513,714,573,523]	4	hSpCas9	negative selection	6581710
100529438	100529461	10	+	27260156	CORL105	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.23486543560475748	[110]	[183,185,150,90]	4	hSpCas9	negative selection	6591913
100545950	100545973	10	+	27260156	HS294T	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.322002304731555	[993]	[196,460,264,311]	-4	hSpCas9	negative selection	6638698
100545959	100545982	10	-	27260156	HS294T	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.1533912665490308	[759]	[284,281,376,375]	2	hSpCas9	negative selection	6638699
100540646	100540669	10	+	27260156	HS294T	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.2980777459151177	[549]	[299,221,206,323]	4	hSpCas9	negative selection	6638700
100529386	100529409	10	-	27260156	HS294T	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.823075616837282	[813]	[138,123,218,245]	-8	hSpCas9	negative selection	6648904
100536414	100536437	10	-	27260156	HS294T	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.14001187720584984	[1365]	[467,489,425,542]	-2	hSpCas9	negative selection	6702959
100536562	100536585	10	+	27260156	HS294T	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.028798741146328855	[139]	[46,63,50,59]	0	hSpCas9	negative selection	6702960
100540706	100540729	10	+	27260156	HS294T	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	-0.028709164120850533	[418]	[112,261,119,136]	0	hSpCas9	negative selection	6702961
100529438	100529461	10	+	27260156	HS294T	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.024094578657660293	[110]	[25,19,57,71]	0	hSpCas9	negative selection	6713164
100545950	100545973	10	+	27260156	HCC44	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5696996327049358	[993]	[768,658,784,827]	-7	hSpCas9	negative selection	6759949
100545959	100545982	10	-	27260156	HCC44	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.23630487689107016	[759]	[1142,873,1511,642]	4	hSpCas9	negative selection	6759950
100540646	100540669	10	+	27260156	HCC44	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.4298850833264434	[549]	[826,879,870,767]	7	hSpCas9	negative selection	6759951
100529386	100529409	10	-	27260156	HCC44	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.7097943614036046	[813]	[711,532,576,448]	-7	hSpCas9	negative selection	6770155
100536414	100536437	10	-	27260156	HCC44	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.0654434361704963	[1365]	[1634,1219,1545,1552]	-1	hSpCas9	negative selection	6824210
100536562	100536585	10	+	27260156	HCC44	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.4163387994831136	[139]	[303,113,165,271]	7	hSpCas9	negative selection	6824211
100540706	100540729	10	+	27260156	HCC44	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.43387010780117574	[418]	[525,623,883,557]	7	hSpCas9	negative selection	6824212
100529438	100529461	10	+	27260156	HCC44	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.365093144711635	[110]	[119,175,131,204]	6	hSpCas9	negative selection	6834415
100545950	100545973	10	+	27260156	G402	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.7159616580430785	[993]	[531,653,1075,657]	-7	hSpCas9	negative selection	6881200
100545959	100545982	10	-	27260156	G402	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.30847892931341936	[759]	[1232,1359,770,1244]	4	hSpCas9	negative selection	6881201
100540646	100540669	10	+	27260156	G402	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.09224639282822097	[549]	[582,822,638,796]	1	hSpCas9	negative selection	6881202
100529386	100529409	10	-	27260156	G402	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.44697636464704504	[813]	[946,446,595,926]	-5	hSpCas9	negative selection	6891406
100536414	100536437	10	-	27260156	G402	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.09839415873305835	[1365]	[2036,1484,1467,1308]	-1	hSpCas9	negative selection	6945461
100536562	100536585	10	+	27260156	G402	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	1.2922106443845567	[139]	[344,635,382,314]	9	hSpCas9	negative selection	6945462
100540706	100540729	10	+	27260156	G402	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.643129648553676	[418]	[1017,560,754,870]	7	hSpCas9	negative selection	6945463
100529438	100529461	10	+	27260156	G402	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.8750856722501525	[110]	[210,440,235,116]	9	hSpCas9	negative selection	6955666
100545950	100545973	10	+	27260156	L33	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5222550653256959	[993]	[785,265,452,610]	-8	hSpCas9	negative selection	7002451
100545959	100545982	10	-	27260156	L33	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.243099999479656	[759]	[892,301,665,908]	5	hSpCas9	negative selection	7002452
100540646	100540669	10	+	27260156	L33	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.33347038875688084	[549]	[627,254,425,843]	7	hSpCas9	negative selection	7002453
100529386	100529409	10	-	27260156	L33	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.6703835880849252	[813]	[507,241,324,430]	-9	hSpCas9	negative selection	7012657
100536414	100536437	10	-	27260156	L33	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.4046427817440841	[1365]	[910,404,764,1014]	-7	hSpCas9	negative selection	7066712
100536562	100536585	10	+	27260156	L33	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.25147138707072303	[139]	[119,66,100,222]	5	hSpCas9	negative selection	7066713
100540706	100540729	10	+	27260156	L33	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.04139542744082325	[418]	[421,199,272,380]	0	hSpCas9	negative selection	7066714
100529438	100529461	10	+	27260156	L33	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.07539948706011046	[110]	[168,46,74,63]	1	hSpCas9	negative selection	7076917
100545950	100545973	10	+	27260156	K562	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5803335786329107	[993]	[569,520,613,640]	-6	hSpCas9	negative selection	7123702
100545959	100545982	10	-	27260156	K562	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.06231476692828197	[759]	[561,857,667,512]	-1	hSpCas9	negative selection	7123703
100540646	100540669	10	+	27260156	K562	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.11228306937617191	[549]	[724,448,388,553]	1	hSpCas9	negative selection	7123704
100529386	100529409	10	-	27260156	K562	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-1.039910394361184	[813]	[403,502,288,233]	-8	hSpCas9	negative selection	7133908
100536414	100536437	10	-	27260156	K562	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.4438293811414391	[1365]	[1603,809,591,638]	-5	hSpCas9	negative selection	7187963
100536562	100536585	10	+	27260156	K562	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.6443551018640901	[139]	[162,291,114,206]	7	hSpCas9	negative selection	7187964
100540706	100540729	10	+	27260156	K562	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.7293846162505933	[418]	[584,863,382,638]	8	hSpCas9	negative selection	7187965
100529438	100529461	10	+	27260156	K562	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.3977696174877272	[110]	[77,155,201,84]	5	hSpCas9	negative selection	7198168
100545950	100545973	10	+	27260156	HT29	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.4616607862924793	[993]	[913,929,1043,650]	-7	hSpCas9	negative selection	7244953
100545959	100545982	10	-	27260156	HT29	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.013728368050566542	[759]	[1075,971,897,807]	0	hSpCas9	negative selection	7244954
100540646	100540669	10	+	27260156	HT29	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.014103082489409696	[549]	[807,559,723,565]	0	hSpCas9	negative selection	7244955
100529386	100529409	10	-	27260156	HT29	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.3051343311776723	[813]	[853,884,839,648]	-5	hSpCas9	negative selection	7255159
100536414	100536437	10	-	27260156	HT29	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.16554361592575062	[1365]	[1602,1515,1344,1461]	-3	hSpCas9	negative selection	7309214
100536562	100536585	10	+	27260156	HT29	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.5911992009166558	[139]	[178,305,226,303]	9	hSpCas9	negative selection	7309215
100540706	100540729	10	+	27260156	HT29	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.036084008660248024	[418]	[466,609,574,445]	0	hSpCas9	negative selection	7309216
100529438	100529461	10	+	27260156	HT29	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.30799377976797926	[110]	[117,146,54,117]	-5	hSpCas9	negative selection	7319419
100545950	100545973	10	+	27260156	MHHES1	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.12009585855192972	[993]	[1143,1108,1178,752]	-2	hSpCas9	negative selection	7366204
100545959	100545982	10	-	27260156	MHHES1	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.027688856052670463	[759]	[834,862,829,817]	0	hSpCas9	negative selection	7366205
100540646	100540669	10	+	27260156	MHHES1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.16056781335296696	[549]	[1017,817,695,353]	3	hSpCas9	negative selection	7366206
100529386	100529409	10	-	27260156	MHHES1	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.044402282541999516	[813]	[1004,776,928,838]	-1	hSpCas9	negative selection	7376410
100536414	100536437	10	-	27260156	MHHES1	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.055908725427446626	[1365]	[1489,1889,1462,1160]	-1	hSpCas9	negative selection	7430465
100536562	100536585	10	+	27260156	MHHES1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.5832384451100792	[139]	[240,413,217,113]	8	hSpCas9	negative selection	7430466
100540706	100540729	10	+	27260156	MHHES1	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.004597884535786939	[418]	[578,486,543,322]	0	hSpCas9	negative selection	7430467
100529438	100529461	10	+	27260156	MHHES1	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.28038023717763627	[110]	[51,100,59,172]	-5	hSpCas9	negative selection	7440670
100545950	100545973	10	+	27260156	MEWO	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.6923732119961223	[993]	[694,468,585]	-8	hSpCas9	negative selection	7487455
100545959	100545982	10	-	27260156	MEWO	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.14763291089901842	[759]	[783,639,528]	-3	hSpCas9	negative selection	7487456
100540646	100540669	10	+	27260156	MEWO	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.024765256359557425	[549]	[793,461,366]	0	hSpCas9	negative selection	7487457
100529386	100529409	10	-	27260156	MEWO	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.2123589531952722	[813]	[874,648,489]	-4	hSpCas9	negative selection	7497661
100536414	100536437	10	-	27260156	MEWO	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.26350885756444353	[1365]	[1250,1015,962]	-5	hSpCas9	negative selection	7551716
100536562	100536585	10	+	27260156	MEWO	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.5454684877578517	[139]	[204,216,153]	9	hSpCas9	negative selection	7551717
100540706	100540729	10	+	27260156	MEWO	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.03024331220772311	[418]	[534,383,307]	0	hSpCas9	negative selection	7551718
100529438	100529461	10	+	27260156	MEWO	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.04046875631477809	[110]	[156,50,105]	-1	hSpCas9	negative selection	7561921
100545950	100545973	10	+	27260156	LNCAPCLONEFGC	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.630864098199287	[993]	[494,626,660,552]	-7	hSpCas9	negative selection	7608706
100545959	100545982	10	-	27260156	LNCAPCLONEFGC	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.23840052309033788	[759]	[808,703,843,902]	4	hSpCas9	negative selection	7608707
100540646	100540669	10	+	27260156	LNCAPCLONEFGC	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.2130691785873475	[549]	[580,594,641,499]	3	hSpCas9	negative selection	7608708
100529386	100529409	10	-	27260156	LNCAPCLONEFGC	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.22354659088081952	[813]	[642,561,819,532]	-4	hSpCas9	negative selection	7618912
100536414	100536437	10	-	27260156	LNCAPCLONEFGC	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.3943865435993974	[1365]	[900,802,1156,945]	-6	hSpCas9	negative selection	7672967
100536562	100536585	10	+	27260156	LNCAPCLONEFGC	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.5695254820479065	[139]	[121,152,266,225]	8	hSpCas9	negative selection	7672968
100540706	100540729	10	+	27260156	LNCAPCLONEFGC	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.3946144506985376	[418]	[333,387,619,681]	6	hSpCas9	negative selection	7672969
100529438	100529461	10	+	27260156	LNCAPCLONEFGC	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.470021729127569	[110]	[171,175,105,94]	7	hSpCas9	negative selection	7683172
100545950	100545973	10	+	27260156	PANC0327	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5618611655882879	[993]	[665,614,649,464]	-7	hSpCas9	negative selection	7729957
100545959	100545982	10	-	27260156	PANC0327	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.25537944768844634	[759]	[723,835,583,1067]	4	hSpCas9	negative selection	7729958
100540646	100540669	10	+	27260156	PANC0327	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.576103265608645	[549]	[723,488,892,837]	8	hSpCas9	negative selection	7729959
100529386	100529409	10	-	27260156	PANC0327	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.3238260395474837	[813]	[549,433,660,681]	-5	hSpCas9	negative selection	7740163
100536414	100536437	10	-	27260156	PANC0327	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.005094242518680625	[1365]	[1204,973,1598,1088]	0	hSpCas9	negative selection	7794218
100536562	100536585	10	+	27260156	PANC0327	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.004442856767105097	[139]	[105,103,138,147]	0	hSpCas9	negative selection	7794219
100540706	100540729	10	+	27260156	PANC0327	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.04860290049233908	[418]	[352,507,271,387]	0	hSpCas9	negative selection	7794220
100529438	100529461	10	+	27260156	PANC0327	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.2140839303980666	[110]	[123,85,48,83]	-3	hSpCas9	negative selection	7804423
100545950	100545973	10	+	27260156	NCIH2009	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5015860580205377	[993]	[1342,798,873]	-6	hSpCas9	negative selection	7851208
100545959	100545982	10	-	27260156	NCIH2009	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.33362715117948505	[759]	[1503,1273,1267]	4	hSpCas9	negative selection	7851209
100540646	100540669	10	+	27260156	NCIH2009	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.02185243613897167	[549]	[976,618,784]	0	hSpCas9	negative selection	7851210
100529386	100529409	10	-	27260156	NCIH2009	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.5738073836902251	[813]	[868,855,584]	-6	hSpCas9	negative selection	7861414
100536414	100536437	10	-	27260156	NCIH2009	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.3378829387912421	[1365]	[1760,1570,1243]	-4	hSpCas9	negative selection	7915469
100536562	100536585	10	+	27260156	NCIH2009	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.7378138082895604	[139]	[401,326,263]	8	hSpCas9	negative selection	7915470
100540706	100540729	10	+	27260156	NCIH2009	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.5126672028663344	[418]	[780,804,907]	7	hSpCas9	negative selection	7915471
100529438	100529461	10	+	27260156	NCIH2009	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.11377748616080074	[110]	[213,182,114]	1	hSpCas9	negative selection	7925674
100545950	100545973	10	+	27260156	NCIH1373	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.49802253839489474	[993]	[514,886,684,269]	-5	hSpCas9	negative selection	7972459
100545959	100545982	10	-	27260156	NCIH1373	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.4029272873461409	[759]	[955,1018,939,420]	4	hSpCas9	negative selection	7972460
100540646	100540669	10	+	27260156	NCIH1373	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.11949735443739026	[549]	[1056,452,717,136]	1	hSpCas9	negative selection	7972461
100529386	100529409	10	-	27260156	NCIH1373	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-1.0242239264976	[813]	[765,310,325,119]	-8	hSpCas9	negative selection	7982665
100536414	100536437	10	-	27260156	NCIH1373	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.27293564437758366	[1365]	[1295,765,1332,460]	-3	hSpCas9	negative selection	8036720
100536562	100536585	10	+	27260156	NCIH1373	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.4089666196633981	[139]	[336,247,133,32]	4	hSpCas9	negative selection	8036721
100540706	100540729	10	+	27260156	NCIH1373	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.5030315724651953	[418]	[713,557,755,169]	5	hSpCas9	negative selection	8036722
100529438	100529461	10	+	27260156	NCIH1373	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.6488344646172912	[110]	[95,413,164,14]	6	hSpCas9	negative selection	8046925
100545950	100545973	10	+	27260156	PATU8902	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-1.0187291586908505	[993]	[623,767,565,816]	-7	hSpCas9	negative selection	8093710
100545959	100545982	10	-	27260156	PATU8902	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.19921158905187192	[759]	[550,910,1143,1034]	-2	hSpCas9	negative selection	8093711
100540646	100540669	10	+	27260156	PATU8902	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.15797628055248908	[549]	[869,480,749,610]	-2	hSpCas9	negative selection	8093712
100529386	100529409	10	-	27260156	PATU8902	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.5931499023484295	[813]	[861,654,737,745]	-5	hSpCas9	negative selection	8103916
100536414	100536437	10	-	27260156	PATU8902	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.405623184160532	[1365]	[1182,1312,1303,2042]	-4	hSpCas9	negative selection	8157971
100536562	100536585	10	+	27260156	PATU8902	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.17518282595874446	[139]	[76,345,99,188]	-2	hSpCas9	negative selection	8157972
100540706	100540729	10	+	27260156	PATU8902	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.2564698879371051	[418]	[865,624,573,753]	2	hSpCas9	negative selection	8157973
100529438	100529461	10	+	27260156	PATU8902	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.43644190681511885	[110]	[52,498,67,260]	4	hSpCas9	negative selection	8168176
100545950	100545973	10	+	27260156	PANC1	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.7368145707845248	[993]	[412,616,598,446]	-8	hSpCas9	negative selection	8214961
100545959	100545982	10	-	27260156	PANC1	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.11022619832312419	[759]	[741,706,620,730]	1	hSpCas9	negative selection	8214962
100540646	100540669	10	+	27260156	PANC1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.3100036952831213	[549]	[642,720,475,527]	5	hSpCas9	negative selection	8214963
100529386	100529409	10	-	27260156	PANC1	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.5623539997582525	[813]	[367,540,450,531]	-7	hSpCas9	negative selection	8225167
100536414	100536437	10	-	27260156	PANC1	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.06836457585920974	[1365]	[1051,1727,839,983]	-1	hSpCas9	negative selection	8279222
100536562	100536585	10	+	27260156	PANC1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.9388287277201113	[139]	[299,219,249,156]	9	hSpCas9	negative selection	8279223
100540706	100540729	10	+	27260156	PANC1	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.2519672012883396	[418]	[415,575,377,375]	4	hSpCas9	negative selection	8279224
100529438	100529461	10	+	27260156	PANC1	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.3811610235162912	[110]	[95,68,297,36]	6	hSpCas9	negative selection	8289427
100545950	100545973	10	+	27260156	PANC0813	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.4654564274548314	[993]	[996,834,914,658]	-6	hSpCas9	negative selection	8336212
100545959	100545982	10	-	27260156	PANC0813	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.46671176452444696	[759]	[1494,1231,1135,1100]	7	hSpCas9	negative selection	8336213
100540646	100540669	10	+	27260156	PANC0813	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.028025277719677527	[549]	[730,638,675,503]	0	hSpCas9	negative selection	8336214
100529386	100529409	10	-	27260156	PANC0813	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.3128370270267114	[813]	[650,898,770,746]	-5	hSpCas9	negative selection	8346418
100536414	100536437	10	-	27260156	PANC0813	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.23843452770460516	[1365]	[1318,1521,1202,1387]	-4	hSpCas9	negative selection	8400473
100536562	100536585	10	+	27260156	PANC0813	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.6891753538690804	[139]	[187,344,375,150]	9	hSpCas9	negative selection	8400474
100540706	100540729	10	+	27260156	PANC0813	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.24893905382236417	[418]	[748,740,515,359]	4	hSpCas9	negative selection	8400475
100529438	100529461	10	+	27260156	PANC0813	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.5952133208270061	[110]	[70,109,82,79]	-7	hSpCas9	negative selection	8410678
100545950	100545973	10	+	27260156	RDES	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.6058323490809893	[993]	[665,673,840,842]	-8	hSpCas9	negative selection	8457463
100545959	100545982	10	-	27260156	RDES	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.11615616497053727	[759]	[625,754,918,975]	-2	hSpCas9	negative selection	8457464
100540646	100540669	10	+	27260156	RDES	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.2897598106963114	[549]	[608,813,783,915]	4	hSpCas9	negative selection	8457465
100529386	100529409	10	-	27260156	RDES	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.44717866121264793	[813]	[611,713,717,695]	-6	hSpCas9	negative selection	8467669
100536414	100536437	10	-	27260156	RDES	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.09726705074310615	[1365]	[1126,1339,1551,1979]	-2	hSpCas9	negative selection	8521724
100536562	100536585	10	+	27260156	RDES	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.3163995638950492	[139]	[186,197,248,159]	5	hSpCas9	negative selection	8521725
100540706	100540729	10	+	27260156	RDES	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.4127615415879512	[418]	[573,600,727,667]	6	hSpCas9	negative selection	8521726
100529438	100529461	10	+	27260156	RDES	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.3355619219646815	[110]	[133,125,276,107]	5	hSpCas9	negative selection	8531929
100545950	100545973	10	+	27260156	PC3	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.45608209222910445	[993]	[308,655,1309,989]	-8	hSpCas9	negative selection	8578714
100545959	100545982	10	-	27260156	PC3	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.14534496468423586	[759]	[588,636,829,695]	-3	hSpCas9	negative selection	8578715
100540646	100540669	10	+	27260156	PC3	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.1426509307387369	[549]	[500,450,922,650]	3	hSpCas9	negative selection	8578716
100529386	100529409	10	-	27260156	PC3	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.45163822062173453	[813]	[359,600,809,737]	-8	hSpCas9	negative selection	8588920
100536414	100536437	10	-	27260156	PC3	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.4694650753235716	[1365]	[546,855,2015,1032]	-8	hSpCas9	negative selection	8642975
100536562	100536585	10	+	27260156	PC3	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.06322110829187189	[139]	[56,144,362,131]	1	hSpCas9	negative selection	8642976
100540706	100540729	10	+	27260156	PC3	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.09801954402407351	[418]	[255,379,910,470]	2	hSpCas9	negative selection	8642977
100529438	100529461	10	+	27260156	PC3	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.1499434790917613	[110]	[69,41,278,180]	3	hSpCas9	negative selection	8653180
100545950	100545973	10	+	27260156	PATU8988T	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.8718870090838865	[993]	[417,485,534,667]	-8	hSpCas9	negative selection	8699965
100545959	100545982	10	-	27260156	PATU8988T	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.11356243568530833	[759]	[953,633,418,709]	-2	hSpCas9	negative selection	8699966
100540646	100540669	10	+	27260156	PATU8988T	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.32371229531994433	[549]	[399,679,222,421]	-5	hSpCas9	negative selection	8699967
100529386	100529409	10	-	27260156	PATU8988T	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.3319962535159712	[813]	[577,701,532,700]	-5	hSpCas9	negative selection	8710171
100536414	100536437	10	-	27260156	PATU8988T	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.6076961418394086	[1365]	[806,774,763,1132]	-7	hSpCas9	negative selection	8764226
100536562	100536585	10	+	27260156	PATU8988T	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.06711092279729658	[139]	[114,234,82,90]	-1	hSpCas9	negative selection	8764227
100540706	100540729	10	+	27260156	PATU8988T	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	-0.017944517803932247	[418]	[339,321,482,449]	0	hSpCas9	negative selection	8764228
100529438	100529461	10	+	27260156	PATU8988T	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.2886627073653416	[110]	[183,134,125,74]	5	hSpCas9	negative selection	8774431
100545950	100545973	10	+	27260156	T47D	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.4016416564579446	[993]	[862,940,704,997]	-7	hSpCas9	negative selection	8821216
100545959	100545982	10	-	27260156	T47D	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.036038156884934724	[759]	[980,795,859,821]	-1	hSpCas9	negative selection	8821217
100540646	100540669	10	+	27260156	T47D	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.28997316281005825	[549]	[723,692,865,858]	6	hSpCas9	negative selection	8821218
100529386	100529409	10	-	27260156	T47D	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.6833753352218082	[813]	[511,567,688,592]	-8	hSpCas9	negative selection	8831422
100536414	100536437	10	-	27260156	T47D	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.23532556234854107	[1365]	[1377,1258,1323,1457]	-5	hSpCas9	negative selection	8885477
100536562	100536585	10	+	27260156	T47D	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.29980555191246205	[139]	[172,199,218,210]	6	hSpCas9	negative selection	8885478
100540706	100540729	10	+	27260156	T47D	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.17535396630788197	[418]	[556,468,583,602]	4	hSpCas9	negative selection	8885479
100529438	100529461	10	+	27260156	T47D	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.1015639050890873	[110]	[127,120,126,181]	2	hSpCas9	negative selection	8895682
100545950	100545973	10	+	27260156	SU8686	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.30251687627724744	[993]	[695,770,711,1067]	-5	hSpCas9	negative selection	8942467
100545959	100545982	10	-	27260156	SU8686	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.21434310402373868	[759]	[803,897,859,943]	3	hSpCas9	negative selection	8942468
100540646	100540669	10	+	27260156	SU8686	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.5428407745531413	[549]	[590,744,862,1044]	8	hSpCas9	negative selection	8942469
100529386	100529409	10	-	27260156	SU8686	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.2753206311545353	[813]	[626,690,647,702]	-5	hSpCas9	negative selection	8952673
100536414	100536437	10	-	27260156	SU8686	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.07050163200078718	[1365]	[1224,1251,1244,1466]	-1	hSpCas9	negative selection	9006728
100536562	100536585	10	+	27260156	SU8686	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.5541511481559895	[139]	[200,141,277,202]	8	hSpCas9	negative selection	9006729
100540706	100540729	10	+	27260156	SU8686	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.10528224091828756	[418]	[441,293,530,557]	1	hSpCas9	negative selection	9006730
100529438	100529461	10	+	27260156	SU8686	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.20307223636355665	[110]	[100,131,96,186]	3	hSpCas9	negative selection	9016933
100545950	100545973	10	+	27260156	SKES1	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5338837883759195	[993]	[834,677,567,673]	-8	hSpCas9	negative selection	9063718
100545959	100545982	10	-	27260156	SKES1	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.09750769771194623	[759]	[1318,767,599,637]	2	hSpCas9	negative selection	9063719
100540646	100540669	10	+	27260156	SKES1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.2998121180965784	[549]	[728,895,570,548]	6	hSpCas9	negative selection	9063720
100529386	100529409	10	-	27260156	SKES1	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.6575313196323764	[813]	[550,576,493,451]	-8	hSpCas9	negative selection	9073924
100536414	100536437	10	-	27260156	SKES1	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.11975841109377172	[1365]	[1568,1470,1168,906]	-3	hSpCas9	negative selection	9127979
100536562	100536585	10	+	27260156	SKES1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.250612500807611	[139]	[203,142,188,132]	5	hSpCas9	negative selection	9127980
100540706	100540729	10	+	27260156	SKES1	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.17535062721192293	[418]	[513,468,403,498]	4	hSpCas9	negative selection	9127981
100529438	100529461	10	+	27260156	SKES1	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.3747373379908969	[110]	[167,125,176,106]	7	hSpCas9	negative selection	9138184
100545950	100545973	10	+	27260156	TOV112D	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.5781901054478239	[993]	[690,944,554,548]	-8	hSpCas9	negative selection	9184969
100545959	100545982	10	-	27260156	TOV112D	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	0.0004207117247878589	[759]	[771,1207,734,448]	0	hSpCas9	negative selection	9184970
100540646	100540669	10	+	27260156	TOV112D	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.0989054093349025	[549]	[432,614,530,495]	-2	hSpCas9	negative selection	9184971
100529386	100529409	10	-	27260156	TOV112D	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.46097010232791136	[813]	[727,715,444,522]	-7	hSpCas9	negative selection	9195175
100536414	100536437	10	-	27260156	TOV112D	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.09745922992566691	[1365]	[1290,1849,961,1154]	-2	hSpCas9	negative selection	9249230
100536562	100536585	10	+	27260156	TOV112D	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.6353285819278838	[139]	[272,246,156,205]	9	hSpCas9	negative selection	9249231
100540706	100540729	10	+	27260156	TOV112D	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	-0.12702981832626206	[418]	[564,389,354,246]	-2	hSpCas9	negative selection	9249232
100529438	100529461	10	+	27260156	TOV112D	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.02141271013370316	[110]	[109,164,79,96]	0	hSpCas9	negative selection	9259435
100545950	100545973	10	+	27260156	TC71	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.324799851042035	[993]	[770,874,803,962]	-7	hSpCas9	negative selection	9306220
100545959	100545982	10	-	27260156	TC71	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.0720834958012958	[759]	[819,808,680,792]	-2	hSpCas9	negative selection	9306221
100540646	100540669	10	+	27260156	TC71	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.13585239568453353	[549]	[407,699,747,742]	3	hSpCas9	negative selection	9306222
100529386	100529409	10	-	27260156	TC71	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.3505389341890275	[813]	[688,650,684,713]	-7	hSpCas9	negative selection	9316426
100536414	100536437	10	-	27260156	TC71	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.27206282656240366	[1365]	[1065,1174,1171,1456]	-6	hSpCas9	negative selection	9370481
100536562	100536585	10	+	27260156	TC71	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.6132342457325886	[139]	[197,276,218,224]	9	hSpCas9	negative selection	9370482
100540706	100540729	10	+	27260156	TC71	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.02395871791152318	[418]	[409,530,415,472]	0	hSpCas9	negative selection	9370483
100529438	100529461	10	+	27260156	TC71	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	-0.2089531106342295	[110]	[83,75,124,127]	-5	hSpCas9	negative selection	9380686
100545950	100545973	10	+	27260156	TC32	viability	TTGACAATCCCGACTACGAGAGG	HIF1AN	ENSG00000166135	-0.6104889409339298	[993]	[527,475,775,727]	-8	hSpCas9	negative selection	9427471
100545959	100545982	10	-	27260156	TC32	viability	ATTAGGGAACCTCTCGTAGTCGG	HIF1AN	ENSG00000166135	-0.18030316710080296	[759]	[718,456,739,639]	-3	hSpCas9	negative selection	9427472
100540646	100540669	10	+	27260156	TC32	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.11078210273671943	[549]	[471,444,750,621]	2	hSpCas9	negative selection	9427473
100529386	100529409	10	-	27260156	TC32	viability	TACGAACCTTACCCGGATGATGG	HIF1AN	ENSG00000166135	-0.47644092099184837	[813]	[412,436,631,771]	-7	hSpCas9	negative selection	9437677
100536414	100536437	10	-	27260156	TC32	viability	TTTGTGTCGGTCAGCACCACAGG	HIF1AN	ENSG00000166135	-0.0440282051737535	[1365]	[1136,902,1794,1314]	0	hSpCas9	negative selection	9491732
100536562	100536585	10	+	27260156	TC32	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.610826510607307	[139]	[176,236,194,166]	8	hSpCas9	negative selection	9491733
100540706	100540729	10	+	27260156	TC32	viability	GAACTGGATTAATAAGCAACAGG	HIF1AN	ENSG00000166135	0.3764093488980662	[418]	[492,337,667,616]	6	hSpCas9	negative selection	9491734
100529438	100529461	10	+	27260156	TC32	viability	CGGCGGCGGCCCGTTCTTCTGGG	HIF1AN	ENSG00000166135	0.18530403990989264	[110]	[89,91,198,113]	3	hSpCas9	negative selection	9501937
100536080	100536103	10	-	27869803	HPAFII	viability after 27 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.7176217888893452	[328]	[132,81,NaN]	-5	hSpCas9	negative selection	9536278
100536085	100536108	10	-	27869803	HPAFII	viability after 27 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.4861940709619462	[691]	[250,266,NaN]	-4	hSpCas9	negative selection	9536279
100536627	100536650	10	+	27869803	HPAFII	viability after 27 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	0.9953958386032751	[16]	[19,15,NaN]	7	hSpCas9	negative selection	9536280
100540760	100540783	10	-	27869803	HPAFII	viability after 27 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.2404721327338386	[104]	[91,8,NaN]	-2	hSpCas9	negative selection	9536281
100545076	100545099	10	-	27869803	HPAFII	viability after 27 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.034963989749302815	[39]	[32,11,NaN]	0	hSpCas9	negative selection	9536282
100546000	100546023	10	+	27869803	HPAFII	viability after 27 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	1.4681488357384063	[111]	[121,196,NaN]	9	hSpCas9	negative selection	9536283
100536080	100536103	10	-	27869803	HPAFII	viability after 15 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.1198664165649106	[328]	[280,352,NaN]	-1	hSpCas9	negative selection	9618727
100536085	100536108	10	-	27869803	HPAFII	viability after 15 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.5777204940793743	[691]	[538,472,NaN]	-6	hSpCas9	negative selection	9618728
100536627	100536650	10	+	27869803	HPAFII	viability after 15 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	0.7790295861119167	[16]	[47,20,NaN]	8	hSpCas9	negative selection	9618729
100540760	100540783	10	-	27869803	HPAFII	viability after 15 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.19852475603320352	[104]	[159,59,NaN]	-2	hSpCas9	negative selection	9618730
100545076	100545099	10	-	27869803	HPAFII	viability after 15 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	1.1896655238098393	[39]	[184,43,NaN]	9	hSpCas9	negative selection	9618731
100546000	100546023	10	+	27869803	HPAFII	viability after 15 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	1.4219209853318455	[111]	[369,292,NaN]	9	hSpCas9	negative selection	9618732
100536080	100536103	10	-	27869803	ASPC1	viability after 36 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	0.24388009746606862	[728]	[486,333,141]	2	hSpCas9	negative selection	9701176
100536085	100536108	10	-	27869803	ASPC1	viability after 36 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.4919944373332459	[1771]	[250,582,453]	-5	hSpCas9	negative selection	9701177
100536627	100536650	10	+	27869803	ASPC1	viability after 36 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-1.572775564439548	[59]	[0,0,15]	-8	hSpCas9	negative selection	9701178
100540760	100540783	10	-	27869803	ASPC1	viability after 36 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	0.13545130200807387	[170]	[28,132,36]	1	hSpCas9	negative selection	9701179
100545076	100545099	10	-	27869803	ASPC1	viability after 36 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	-2.2074729327340328	[249]	[0,56,0]	-9	hSpCas9	negative selection	9701180
100546000	100546023	10	+	27869803	ASPC1	viability after 36 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.016078731259814016	[454]	[20,200,215]	0	hSpCas9	negative selection	9701181
100536080	100536103	10	-	27869803	PATU8988S	viability after 35 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.12096882979410943	[616]	[232,223,NaN]	-1	hSpCas9	negative selection	9783625
100536085	100536108	10	-	27869803	PATU8988S	viability after 35 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.2739795354787753	[1398]	[461,469,NaN]	-3	hSpCas9	negative selection	9783626
100536627	100536650	10	+	27869803	PATU8988S	viability after 35 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.04700116799052223	[99]	[31,45,NaN]	0	hSpCas9	negative selection	9783627
100540760	100540783	10	-	27869803	PATU8988S	viability after 35 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.1477551110110358	[239]	[287,139,NaN]	9	hSpCas9	negative selection	9783628
100545076	100545099	10	-	27869803	PATU8988S	viability after 35 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.11967935531662022	[119]	[56,47,NaN]	1	hSpCas9	negative selection	9783629
100546000	100546023	10	+	27869803	PATU8988S	viability after 35 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-1.0747163730787568	[360]	[80,56,NaN]	-7	hSpCas9	negative selection	9783630
100536080	100536103	10	-	27869803	PATU8988S	viability after 31 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.2916403483039003	[616]	[178,228,NaN]	-3	hSpCas9	negative selection	9866074
100536085	100536108	10	-	27869803	PATU8988S	viability after 31 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.18189376782015976	[1398]	[634,629,NaN]	2	hSpCas9	negative selection	9866075
100536627	100536650	10	+	27869803	PATU8988S	viability after 31 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-0.23503475350416414	[99]	[32,34,NaN]	-3	hSpCas9	negative selection	9866076
100540760	100540783	10	-	27869803	PATU8988S	viability after 31 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	1.183552969433705	[239]	[241,185,NaN]	9	hSpCas9	negative selection	9866077
100545076	100545099	10	-	27869803	PATU8988S	viability after 31 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.017768388338869734	[119]	[58,34,NaN]	0	hSpCas9	negative selection	9866078
100546000	100546023	10	+	27869803	PATU8988S	viability after 31 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	-0.6820855442211611	[360]	[72,110,NaN]	-6	hSpCas9	negative selection	9866079
100536080	100536103	10	-	27869803	HPAFII	viability after 35 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-1.7480239451363415	[328]	[42,56,NaN]	-7	hSpCas9	negative selection	9948523
100536085	100536108	10	-	27869803	HPAFII	viability after 35 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.5397923126638571	[691]	[192,294,NaN]	-3	hSpCas9	negative selection	9948524
100536627	100536650	10	+	27869803	HPAFII	viability after 35 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	1.4965946377731818	[16]	[4,45,NaN]	8	hSpCas9	negative selection	9948525
100540760	100540783	10	-	27869803	HPAFII	viability after 35 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-1.5955609186226352	[104]	[18,15,NaN]	-7	hSpCas9	negative selection	9948526
100545076	100545099	10	-	27869803	HPAFII	viability after 35 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.4496876597297579	[39]	[45,6,NaN]	3	hSpCas9	negative selection	9948527
100546000	100546023	10	+	27869803	HPAFII	viability after 35 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	2.1222233107686566	[111]	[61,454,NaN]	9	hSpCas9	negative selection	9948528
100536080	100536103	10	-	27869803	HPAFII	viability after 31 days	GCTCTGACTCAGACGCGGAATGG	HIF1AN	ENSG00000166135	-0.3608677098806261	[328]	[149,136,NaN]	-2	hSpCas9	negative selection	10030972
100536085	100536108	10	-	27869803	HPAFII	viability after 31 days	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.3284606404049837	[691]	[337,277,NaN]	-2	hSpCas9	negative selection	10030973
100536627	100536650	10	+	27869803	HPAFII	viability after 31 days	CTGCAGGATATACAGCAGCGAGG	HIF1AN	ENSG00000166135	-1.0368609253544125	[16]	[7,0,NaN]	-6	hSpCas9	negative selection	10030974
100540760	100540783	10	-	27869803	HPAFII	viability after 31 days	CTTCCATGCCAATGAGCAGCAGG	HIF1AN	ENSG00000166135	-0.6221400495906968	[104]	[66,6,NaN]	-4	hSpCas9	negative selection	10030975
100545076	100545099	10	-	27869803	HPAFII	viability after 31 days	ACCTGGCTCTGTCTGTCACATGG	HIF1AN	ENSG00000166135	0.940580801111593	[39]	[44,40,NaN]	7	hSpCas9	negative selection	10030976
100546000	100546023	10	+	27869803	HPAFII	viability after 31 days	TACGAAACAGTGGTTGGCCCTGG	HIF1AN	ENSG00000166135	1.3996893439350022	[111]	[72,266,NaN]	8	hSpCas9	negative selection	10030977
100546017	100546040	10	-	28162770	P31FUJ	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.5044326339365577	[302]	[250]	-4	hSpCas9	negative selection	10168819
100545051	100545074	10	-	28162770	P31FUJ	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	0.16147673469766777	[69]	[91]	1	hSpCas9	negative selection	10168820
100536085	100536108	10	-	28162770	P31FUJ	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-1.2006217986652288	[132]	[67]	-7	hSpCas9	negative selection	10168821
100536630	100536653	10	+	28162770	P31FUJ	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	0.5772268519415508	[76]	[134]	6	hSpCas9	negative selection	10168822
100540646	100540669	10	+	28162770	P31FUJ	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.33835449678174717	[209]	[311]	3	hSpCas9	negative selection	10168823
100536562	100536585	10	+	28162770	P31FUJ	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.21345402547518533	[79]	[108]	2	hSpCas9	negative selection	10168824
100540722	100540745	10	+	28162770	P31FUJ	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.8805004604834976	[46]	[29]	-6	hSpCas9	negative selection	10168825
100545030	100545053	10	-	28162770	P31FUJ	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-0.33233787796529296	[209]	[195]	-3	hSpCas9	negative selection	10168826
100547214	100547237	10	+	28162770	P31FUJ	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.19084842516917327	[166]	[223]	2	hSpCas9	negative selection	10168827
100535987	100536010	10	-	28162770	P31FUJ	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.34466575975985325	[192]	[287]	4	hSpCas9	negative selection	10168828
100546017	100546040	10	-	28162770	TF1	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[216]	1	hSpCas9	negative selection	10338185
100545051	100545074	10	-	28162770	TF1	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[103]	1	hSpCas9	negative selection	10338186
100536085	100536108	10	-	28162770	TF1	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10338187
100536630	100536653	10	+	28162770	TF1	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10338188
100540646	100540669	10	+	28162770	TF1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10338189
100536562	100536585	10	+	28162770	TF1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10338190
100540722	100540745	10	+	28162770	TF1	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[33]	1	hSpCas9	negative selection	10338191
100545030	100545053	10	-	28162770	TF1	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[109]	1	hSpCas9	negative selection	10338192
100547214	100547237	10	+	28162770	TF1	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10338193
100535987	100536010	10	-	28162770	TF1	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10338194
100546017	100546040	10	-	28162770	SKM1	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.0429106281831228	[80]	[138]	0	hSpCas9	negative selection	10507551
100545051	100545074	10	-	28162770	SKM1	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.5996092766855576	[17]	[20]	-5	hSpCas9	negative selection	10507552
100536085	100536108	10	-	28162770	SKM1	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-1.8559490299453432	[42]	[20]	-8	hSpCas9	negative selection	10507553
100536630	100536653	10	+	28162770	SKM1	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-1.6479722982469567	[38]	[21]	-8	hSpCas9	negative selection	10507554
100540646	100540669	10	+	28162770	SKM1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.319354151223536	[67]	[149]	3	hSpCas9	negative selection	10507555
100536562	100536585	10	+	28162770	SKM1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.32483969030726567	[27]	[61]	3	hSpCas9	negative selection	10507556
100540722	100540745	10	+	28162770	SKM1	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.14392979290936792	[4]	[7]	-1	hSpCas9	negative selection	10507557
100545030	100545053	10	-	28162770	SKM1	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-1.7033572015233864	[34]	[18]	-8	hSpCas9	negative selection	10507558
100547214	100547237	10	+	28162770	SKM1	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.21647244979263014	[36]	[75]	2	hSpCas9	negative selection	10507559
100535987	100536010	10	-	28162770	SKM1	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	-0.0025739436638264335	[50]	[89]	0	hSpCas9	negative selection	10507560
100546017	100546040	10	-	28162770	SKM1	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.0429106281831228	[80]	[138]	0	hSpCas9	negative selection	10676917
100545051	100545074	10	-	28162770	SKM1	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.5996092766855576	[17]	[20]	-5	hSpCas9	negative selection	10676918
100536085	100536108	10	-	28162770	SKM1	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-1.8559490299453432	[42]	[20]	-8	hSpCas9	negative selection	10676919
100536630	100536653	10	+	28162770	SKM1	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-1.6479722982469567	[38]	[21]	-8	hSpCas9	negative selection	10676920
100540646	100540669	10	+	28162770	SKM1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.319354151223536	[67]	[149]	3	hSpCas9	negative selection	10676921
100536562	100536585	10	+	28162770	SKM1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.32483969030726567	[27]	[61]	3	hSpCas9	negative selection	10676922
100540722	100540745	10	+	28162770	SKM1	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.14392979290936792	[4]	[7]	-1	hSpCas9	negative selection	10676923
100545030	100545053	10	-	28162770	SKM1	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-1.7033572015233864	[34]	[18]	-8	hSpCas9	negative selection	10676924
100547214	100547237	10	+	28162770	SKM1	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.21647244979263014	[36]	[75]	2	hSpCas9	negative selection	10676925
100535987	100536010	10	-	28162770	SKM1	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	-0.0025739436638264335	[50]	[89]	0	hSpCas9	negative selection	10676926
100546017	100546040	10	-	28162770	PL21	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	0.3350691945754286	[305]	[167]	3	hSpCas9	negative selection	10846283
100545051	100545074	10	-	28162770	PL21	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	0.5371746017668908	[75]	[47]	5	hSpCas9	negative selection	10846284
100536085	100536108	10	-	28162770	PL21	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.4389264740764367	[99]	[58]	4	hSpCas9	negative selection	10846285
100536630	100536653	10	+	28162770	PL21	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-0.2404329768966612	[132]	[48]	-2	hSpCas9	negative selection	10846286
100540646	100540669	10	+	28162770	PL21	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.13807864635706854	[189]	[90]	1	hSpCas9	negative selection	10846287
100536562	100536585	10	+	28162770	PL21	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.9842849566481071	[99]	[21]	-6	hSpCas9	negative selection	10846288
100540722	100540745	10	+	28162770	PL21	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	0.434604868126343	[33]	[19]	4	hSpCas9	negative selection	10846289
100545030	100545053	10	-	28162770	PL21	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-1.384822886231836	[95]	[15]	-7	hSpCas9	negative selection	10846290
100547214	100547237	10	+	28162770	PL21	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	-0.8366971536910512	[118]	[28]	-5	hSpCas9	negative selection	10846291
100535987	100536010	10	-	28162770	PL21	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.8533368509629284	[116]	[91]	7	hSpCas9	negative selection	10846292
100546017	100546040	10	-	28162770	P31FUJ	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.5044326339365577	[302]	[250]	-4	hSpCas9	negative selection	11015649
100545051	100545074	10	-	28162770	P31FUJ	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	0.16147673469766777	[69]	[91]	1	hSpCas9	negative selection	11015650
100536085	100536108	10	-	28162770	P31FUJ	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-1.2006217986652288	[132]	[67]	-7	hSpCas9	negative selection	11015651
100536630	100536653	10	+	28162770	P31FUJ	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	0.5772268519415508	[76]	[134]	6	hSpCas9	negative selection	11015652
100540646	100540669	10	+	28162770	P31FUJ	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.33835449678174717	[209]	[311]	3	hSpCas9	negative selection	11015653
100536562	100536585	10	+	28162770	P31FUJ	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.21345402547518533	[79]	[108]	2	hSpCas9	negative selection	11015654
100540722	100540745	10	+	28162770	P31FUJ	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.8805004604834976	[46]	[29]	-6	hSpCas9	negative selection	11015655
100545030	100545053	10	-	28162770	P31FUJ	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-0.33233787796529296	[209]	[195]	-3	hSpCas9	negative selection	11015656
100547214	100547237	10	+	28162770	P31FUJ	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.19084842516917327	[166]	[223]	2	hSpCas9	negative selection	11015657
100535987	100536010	10	-	28162770	P31FUJ	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.34466575975985325	[192]	[287]	4	hSpCas9	negative selection	11015658
100546017	100546040	10	-	28162770	OCIAML5	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.2494020684093817	[161]	[245]	-2	hSpCas9	negative selection	11185015
100545051	100545074	10	-	28162770	OCIAML5	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.25924195236987013	[60]	[91]	-2	hSpCas9	negative selection	11185016
100536085	100536108	10	-	28162770	OCIAML5	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.9567639495306902	[99]	[92]	-5	hSpCas9	negative selection	11185017
100536630	100536653	10	+	28162770	OCIAML5	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-0.7045093824501392	[64]	[71]	-4	hSpCas9	negative selection	11185018
100540646	100540669	10	+	28162770	OCIAML5	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.4936125999515207	[155]	[199]	-3	hSpCas9	negative selection	11185019
100536562	100536585	10	+	28162770	OCIAML5	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.96609510615019	[37]	[133]	8	hSpCas9	negative selection	11185020
100540722	100540745	10	+	28162770	OCIAML5	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.4828327611982779	[23]	[30]	-3	hSpCas9	negative selection	11185021
100545030	100545053	10	-	28162770	OCIAML5	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	0.28676113383331964	[98]	[217]	2	hSpCas9	negative selection	11185022
100547214	100547237	10	+	28162770	OCIAML5	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	1.2739413140481084	[62]	[274]	9	hSpCas9	negative selection	11185023
100535987	100536010	10	-	28162770	OCIAML5	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	-0.8420824822913748	[143]	[144]	-5	hSpCas9	negative selection	11185024
100546017	100546040	10	-	28162770	EOL1	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.5249781040935999	[507]	[185]	-4	hSpCas9	negative selection	11354381
100545051	100545074	10	-	28162770	EOL1	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	0.2173295207983803	[79]	[48]	2	hSpCas9	negative selection	11354382
100536085	100536108	10	-	28162770	EOL1	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-0.8828071504870694	[244]	[69]	-6	hSpCas9	negative selection	11354383
100536630	100536653	10	+	28162770	EOL1	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-0.5181621461928637	[192]	[70]	-4	hSpCas9	negative selection	11354384
100540646	100540669	10	+	28162770	EOL1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.017966733768705445	[368]	[191]	0	hSpCas9	negative selection	11354385
100536562	100536585	10	+	28162770	EOL1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	1.1455181178377845	[144]	[168]	8	hSpCas9	negative selection	11354386
100540722	100540745	10	+	28162770	EOL1	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.9234491349844158	[35]	[9]	-6	hSpCas9	negative selection	11354387
100545030	100545053	10	-	28162770	EOL1	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-0.8530598070930175	[167]	[48]	-5	hSpCas9	negative selection	11354388
100547214	100547237	10	+	28162770	EOL1	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.32415523027977244	[140]	[92]	3	hSpCas9	negative selection	11354389
100535987	100536010	10	-	28162770	EOL1	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.08582867860359522	[185]	[103]	0	hSpCas9	negative selection	11354390
100546017	100546040	10	-	28162770	MOLM13	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	0.8475625950711164	[381]	[496]	6	hSpCas9	negative selection	11523747
100545051	100545074	10	-	28162770	MOLM13	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.2572507772248376	[80]	[48]	-1	hSpCas9	negative selection	11523748
100536085	100536108	10	-	28162770	MOLM13	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.3348639629137956	[192]	[175]	2	hSpCas9	negative selection	11523749
100536630	100536653	10	+	28162770	MOLM13	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	1.082599225659787	[127]	[195]	8	hSpCas9	negative selection	11523750
100540646	100540669	10	+	28162770	MOLM13	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.43265220148803724	[372]	[363]	3	hSpCas9	negative selection	11523751
100536562	100536585	10	+	28162770	MOLM13	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.9533162087148207	[129]	[181]	7	hSpCas9	negative selection	11523752
100540722	100540745	10	+	28162770	MOLM13	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.9471481177342649	[31]	[11]	-5	hSpCas9	negative selection	11523753
100545030	100545053	10	-	28162770	MOLM13	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	0.18031279144799361	[165]	[135]	1	hSpCas9	negative selection	11523754
100547214	100547237	10	+	28162770	MOLM13	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	-0.12672328921029669	[224]	[148]	-1	hSpCas9	negative selection	11523755
100535987	100536010	10	-	28162770	MOLM13	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	1.0024339752795117	[164]	[238]	7	hSpCas9	negative selection	11523756
100546017	100546040	10	-	28162770	HEL	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	0.3962268820792252	[381]	[321]	3	hSpCas9	negative selection	11693113
100545051	100545074	10	-	28162770	HEL	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	0.8733517601417732	[74]	[87]	7	hSpCas9	negative selection	11693114
100536085	100536108	10	-	28162770	HEL	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	1.1245024450800138	[168]	[235]	8	hSpCas9	negative selection	11693115
100536630	100536653	10	+	28162770	HEL	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	0.7186876852336554	[147]	[155]	6	hSpCas9	negative selection	11693116
100540646	100540669	10	+	28162770	HEL	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.5090603967683877	[225]	[205]	4	hSpCas9	negative selection	11693117
100536562	100536585	10	+	28162770	HEL	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	1.0577763312792008	[107]	[143]	8	hSpCas9	negative selection	11693118
100540722	100540745	10	+	28162770	HEL	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	0.7496540359168693	[38]	[41]	6	hSpCas9	negative selection	11693119
100545030	100545053	10	-	28162770	HEL	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	0.3778416821493736	[154]	[128]	3	hSpCas9	negative selection	11693120
100547214	100547237	10	+	28162770	HEL	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	-0.46862227694734715	[174]	[80]	-3	hSpCas9	negative selection	11693121
100535987	100536010	10	-	28162770	HEL	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.7819015796719823	[157]	[173]	6	hSpCas9	negative selection	11693122
100546017	100546040	10	-	28162770	MV411	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	0.187455445954543	[220]	[211]	1	hSpCas9	negative selection	11862479
100545051	100545074	10	-	28162770	MV411	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.4370606234892951	[44]	[27]	-3	hSpCas9	negative selection	11862480
100536085	100536108	10	-	28162770	MV411	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.0898962737962955	[144]	[129]	0	hSpCas9	negative selection	11862481
100536630	100536653	10	+	28162770	MV411	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	0.03513394706991124	[94]	[81]	0	hSpCas9	negative selection	11862482
100540646	100540669	10	+	28162770	MV411	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.06376413751152865	[200]	[161]	0	hSpCas9	negative selection	11862483
100536562	100536585	10	+	28162770	MV411	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-0.13862088152430263	[114]	[87]	-1	hSpCas9	negative selection	11862484
100540722	100540745	10	+	28162770	MV411	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	0.40970897968165265	[41]	[46]	3	hSpCas9	negative selection	11862485
100545030	100545053	10	-	28162770	MV411	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	0.8408122913201317	[56]	[85]	7	hSpCas9	negative selection	11862486
100547214	100547237	10	+	28162770	MV411	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.7309547879443856	[107]	[150]	6	hSpCas9	negative selection	11862487
100535987	100536010	10	-	28162770	MV411	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	-0.17681847852544713	[156]	[116]	-1	hSpCas9	negative selection	11862488
100546017	100546040	10	-	28162770	MONOMAC1	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.0014860379417468428	[185]	[212]	0	hSpCas9	negative selection	12031845
100545051	100545074	10	-	28162770	MONOMAC1	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.0006396342560504031	[47]	[54]	0	hSpCas9	negative selection	12031846
100536085	100536108	10	-	28162770	MONOMAC1	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.19889182927158544	[113]	[149]	2	hSpCas9	negative selection	12031847
100536630	100536653	10	+	28162770	MONOMAC1	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	0.23105680504473658	[54]	[73]	2	hSpCas9	negative selection	12031848
100540646	100540669	10	+	28162770	MONOMAC1	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.26983958373890815	[122]	[169]	2	hSpCas9	negative selection	12031849
100536562	100536585	10	+	28162770	MONOMAC1	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.6592276754789967	[57]	[104]	6	hSpCas9	negative selection	12031850
100540722	100540745	10	+	28162770	MONOMAC1	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	1.2180006522192903	[17]	[47]	9	hSpCas9	negative selection	12031851
100545030	100545053	10	-	28162770	MONOMAC1	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	0.5641762933533296	[58]	[99]	5	hSpCas9	negative selection	12031852
100547214	100547237	10	+	28162770	MONOMAC1	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	-0.5235376717367403	[78]	[62]	-4	hSpCas9	negative selection	12031853
100535987	100536010	10	-	28162770	MONOMAC1	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	1.2883899801106882	[94]	[265]	9	hSpCas9	negative selection	12031854
100546017	100546040	10	-	28162770	OCIAML2	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.223989857659036	[58]	[279]	-2	hSpCas9	negative selection	12201211
100545051	100545074	10	-	28162770	OCIAML2	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.24033220582036718	[12]	[60]	-2	hSpCas9	negative selection	12201212
100536085	100536108	10	-	28162770	OCIAML2	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	0.0506070778686078	[26]	[154]	0	hSpCas9	negative selection	12201213
100536630	100536653	10	+	28162770	OCIAML2	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	1.1276294980924528	[17]	[217]	9	hSpCas9	negative selection	12201214
100540646	100540669	10	+	28162770	OCIAML2	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	0.3159665366486454	[49]	[344]	3	hSpCas9	negative selection	12201215
100536562	100536585	10	+	28162770	OCIAML2	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	0.22980989289893095	[17]	[116]	2	hSpCas9	negative selection	12201216
100540722	100540745	10	+	28162770	OCIAML2	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	1.0212232710875133	[3]	[44]	8	hSpCas9	negative selection	12201217
100545030	100545053	10	-	28162770	OCIAML2	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	0.5760634102058804	[18]	[156]	5	hSpCas9	negative selection	12201218
100547214	100547237	10	+	28162770	OCIAML2	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	1.6503855757192047	[19]	[347]	9	hSpCas9	negative selection	12201219
100535987	100536010	10	-	28162770	OCIAML2	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.34565822158545073	[22]	[161]	3	hSpCas9	negative selection	12201220
100546017	100546040	10	-	28162770	OCIAML3	viability	GGATGTAAAGAACATCACCAGGG	HIF1AN	ENSG00000166135	-0.3402510480783801	[64]	[154]	-3	hSpCas9	negative selection	12370577
100545051	100545074	10	-	28162770	OCIAML3	viability	GATGAACAGGGTATGGGTAGAGG	HIF1AN	ENSG00000166135	-0.3086054214619147	[15]	[38]	-2	hSpCas9	negative selection	12370578
100536085	100536108	10	-	28162770	OCIAML3	viability	GGGTCGCTCTGACTCAGACGCGG	HIF1AN	ENSG00000166135	-1.031071445933006	[43]	[64]	-6	hSpCas9	negative selection	12370579
100536630	100536653	10	+	28162770	OCIAML3	viability	CAGGATATACAGCAGCGAGGAGG	HIF1AN	ENSG00000166135	-0.797541034409295	[18]	[32]	-5	hSpCas9	negative selection	12370580
100540646	100540669	10	+	28162770	OCIAML3	viability	GCAAACGCTCAATGACACTGTGG	HIF1AN	ENSG00000166135	-0.4615573443005136	[51]	[113]	-4	hSpCas9	negative selection	12370581
100536562	100536585	10	+	28162770	OCIAML3	viability	ATTTCCAGAACTTTAAGCCGAGG	HIF1AN	ENSG00000166135	-2.030106755130837	[22]	[16]	-8	hSpCas9	negative selection	12370582
100540722	100540745	10	+	28162770	OCIAML3	viability	CAACAGGGAAAGCGTGGCTGGGG	HIF1AN	ENSG00000166135	-0.4944719667732489	[6]	[14]	-4	hSpCas9	negative selection	12370583
100545030	100545053	10	-	28162770	OCIAML3	viability	GGCACTCGAACTGATCCGGAGGG	HIF1AN	ENSG00000166135	-0.2720795454368007	[37]	[94]	-2	hSpCas9	negative selection	12370584
100547214	100547237	10	+	28162770	OCIAML3	viability	GAAGATGCTTGGAGAGGCCTTGG	HIF1AN	ENSG00000166135	0.38461870888327	[16]	[66]	3	hSpCas9	negative selection	12370585
100535987	100536010	10	-	28162770	OCIAML3	viability	CCGGGGCTCTCCAGAGCCAGAGG	HIF1AN	ENSG00000166135	0.3211034620893239	[34]	[131]	3	hSpCas9	negative selection	12370586