Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10114
• Symbol:HIPK3
• Description:homeodomain interacting protein kinase 3

DataSource: http://genomecrispr.dkfz.de/#!/results/HIPK3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
33347683	33347706	11	-	26472758	Jiyoye	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.3513221467723559	[78]	[75]	2	hSpCas9	negative selection	70796
33349245	33349268	11	-	26472758	Jiyoye	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.9692004974038655	[134]	[51]	-6	hSpCas9	negative selection	70797
33348745	33348768	11	-	26472758	Jiyoye	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	1.4427992912365948	[39]	[81]	8	hSpCas9	negative selection	70798
33286708	33286731	11	+	26472758	Jiyoye	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.16255301278595993	[108]	[91]	1	hSpCas9	negative selection	70799
33286795	33286818	11	+	26472758	Jiyoye	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.5167998726803714	[75]	[81]	4	hSpCas9	negative selection	70800
33286901	33286924	11	+	26472758	Jiyoye	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	-0.2173154834019202	[36]	[23]	-1	hSpCas9	negative selection	70801
33328509	33328532	11	+	26472758	Jiyoye	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.12904240449819593	[364]	[300]	1	hSpCas9	negative selection	70802
33347352	33347375	11	-	26472758	Jiyoye	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.21649181989676372	[104]	[91]	1	hSpCas9	negative selection	70803
33347892	33347915	11	-	26472758	Jiyoye	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	-0.246648977360087	[117]	[74]	-2	hSpCas9	negative selection	70804
33348692	33348715	11	+	26472758	Jiyoye	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	-0.338251791408529	[56]	[33]	-2	hSpCas9	negative selection	70805
33347683	33347706	11	-	26472758	KBM7	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.42065840443023544	[391,296]	[274,160]	4	hSpCas9	negative selection	261914
33349245	33349268	11	-	26472758	KBM7	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.01674772688609341	[726,417]	[268,251]	0	hSpCas9	negative selection	261915
33348745	33348768	11	-	26472758	KBM7	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-0.27892668671052134	[307,232]	[134,75]	-3	hSpCas9	negative selection	261916
33286708	33286731	11	+	26472758	KBM7	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	-0.028035075713862115	[476,500]	[327,136]	0	hSpCas9	negative selection	261917
33286795	33286818	11	+	26472758	KBM7	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-0.11437255619014078	[416,380]	[128,212]	-1	hSpCas9	negative selection	261918
33286901	33286924	11	+	26472758	KBM7	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	0.022955692957173923	[297,176]	[109,111]	0	hSpCas9	negative selection	261919
33328509	33328532	11	+	26472758	KBM7	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.33074004127367984	[830,916]	[456,579]	3	hSpCas9	negative selection	261920
33347352	33347375	11	-	26472758	KBM7	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.26117249012911414	[617,524]	[378,268]	2	hSpCas9	negative selection	261921
33347892	33347915	11	-	26472758	KBM7	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	-0.048558800061870744	[305,457]	[129,220]	0	hSpCas9	negative selection	261922
33348692	33348715	11	+	26472758	KBM7	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.03766997018113785	[314,497]	[226,178]	0	hSpCas9	negative selection	261923
33347683	33347706	11	-	26472758	Raji	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	1.0964952192308632	[132]	[65]	8	hSpCas9	negative selection	453032
33349245	33349268	11	-	26472758	Raji	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.6250665776701138	[318]	[47]	-5	hSpCas9	negative selection	453033
33348745	33348768	11	-	26472758	Raji	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-0.09425032579605097	[114]	[24]	-1	hSpCas9	negative selection	453034
33286708	33286731	11	+	26472758	Raji	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	1.6190970540641172	[100]	[71]	9	hSpCas9	negative selection	453035
33286795	33286818	11	+	26472758	Raji	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.1590163037889219	[246]	[63]	1	hSpCas9	negative selection	453036
33286901	33286924	11	+	26472758	Raji	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	1.4293116302609619	[63]	[39]	9	hSpCas9	negative selection	453037
33328509	33328532	11	+	26472758	Raji	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	-0.4730775731126158	[639]	[106]	-4	hSpCas9	negative selection	453038
33347352	33347375	11	-	26472758	Raji	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.3377647238886418	[282]	[82]	3	hSpCas9	negative selection	453039
33347892	33347915	11	-	26472758	Raji	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.27956451075627964	[212]	[59]	2	hSpCas9	negative selection	453040
33348692	33348715	11	+	26472758	Raji	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.556569257064289	[166]	[56]	5	hSpCas9	negative selection	453041
33347683	33347706	11	-	26472758	K562	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.4546364350567927	[203]	[235]	3	hSpCas9	negative selection	644150
33349245	33349268	11	-	26472758	K562	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.6049594092868638	[417]	[231]	-4	hSpCas9	negative selection	644151
33348745	33348768	11	-	26472758	K562	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	0.5623888089851261	[145]	[181]	4	hSpCas9	negative selection	644152
33286708	33286731	11	+	26472758	K562	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.6195340603702688	[228]	[296]	5	hSpCas9	negative selection	644153
33286795	33286818	11	+	26472758	K562	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-0.18947779886371285	[307]	[227]	-1	hSpCas9	negative selection	644154
33286901	33286924	11	+	26472758	K562	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	0.8052687722707956	[180]	[266]	6	hSpCas9	negative selection	644155
33328509	33328532	11	+	26472758	K562	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	-0.42222109205613223	[1080]	[680]	-3	hSpCas9	negative selection	644156
33347352	33347375	11	-	26472758	K562	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.5423715497034689	[448]	[551]	4	hSpCas9	negative selection	644157
33347892	33347915	11	-	26472758	K562	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.8854888946103343	[310]	[484]	7	hSpCas9	negative selection	644158
33348692	33348715	11	+	26472758	K562	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.24021873913716124	[343]	[342]	1	hSpCas9	negative selection	644159
33287316	33287339	11	-	26627737	DLD1	viability	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.4095684963707221	[601]	[284,240,226]	4	hSpCas9	negative selection	778266
33328592	33328615	11	+	26627737	DLD1	viability	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.20867303355054156	[663]	[271,228,220]	2	hSpCas9	negative selection	778267
33347379	33347402	11	+	26627737	DLD1	viability	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.1684095594208883	[1057]	[358,244,278]	-2	hSpCas9	negative selection	778268
33347612	33347635	11	+	26627737	DLD1	viability	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.7401487873421324	[263]	[147,91,166]	7	hSpCas9	negative selection	778269
33348179	33348202	11	+	26627737	DLD1	viability	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.6290576030745514	[144]	[63,107,43]	6	hSpCas9	negative selection	778270
33348627	33348650	11	+	26627737	DLD1	viability	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	0.47252166053306305	[270]	[110,118,121]	5	hSpCas9	negative selection	778271
33287316	33287339	11	-	26627737	GBM cells	viability after 5 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.0902251324825476	[396]	[218,180]	-1	hSpCas9	negative selection	860581
33328592	33328615	11	+	26627737	GBM cells	viability after 5 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-0.2867784424149433	[206]	[98,82]	-4	hSpCas9	negative selection	860582
33347379	33347402	11	+	26627737	GBM cells	viability after 5 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.5488722067328704	[400]	[111,181]	-7	hSpCas9	negative selection	860583
33347612	33347635	11	+	26627737	GBM cells	viability after 5 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.16601794502852635	[176]	[111,100]	2	hSpCas9	negative selection	860584
33348179	33348202	11	+	26627737	GBM cells	viability after 5 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.054431452506972344	[122]	[55,80]	0	hSpCas9	negative selection	860585
33348627	33348650	11	+	26627737	GBM cells	viability after 5 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.5554365484179843	[247]	[68,111]	-7	hSpCas9	negative selection	860586
33287316	33287339	11	-	26627737	GBM cells	viability after 13 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.2121739907157053	[396]	[275,227]	2	hSpCas9	negative selection	942896
33328592	33328615	11	+	26627737	GBM cells	viability after 13 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.4099900444138384	[206]	[119,172]	5	hSpCas9	negative selection	942897
33347379	33347402	11	+	26627737	GBM cells	viability after 13 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-1.0416441734054918	[400]	[108,102]	-8	hSpCas9	negative selection	942898
33347612	33347635	11	+	26627737	GBM cells	viability after 13 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.12337858944145524	[176]	[156,61]	1	hSpCas9	negative selection	942899
33348179	33348202	11	+	26627737	GBM cells	viability after 13 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.756195853535008	[122]	[104,118]	8	hSpCas9	negative selection	942900
33348627	33348650	11	+	26627737	GBM cells	viability after 13 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-1.0970038886819915	[247]	[79,48]	-8	hSpCas9	negative selection	942901
33287316	33287339	11	-	26627737	GBM cells	viability after 21 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.14776951697503782	[396]	[251,226]	1	hSpCas9	negative selection	1025211
33328592	33328615	11	+	26627737	GBM cells	viability after 21 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.16897940280205198	[206]	[127,124]	1	hSpCas9	negative selection	1025212
33347379	33347402	11	+	26627737	GBM cells	viability after 21 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.7291596950486124	[400]	[144,118]	-6	hSpCas9	negative selection	1025213
33347612	33347635	11	+	26627737	GBM cells	viability after 21 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.579878616676648	[176]	[149,137]	6	hSpCas9	negative selection	1025214
33348179	33348202	11	+	26627737	GBM cells	viability after 21 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.6277943904593213	[122]	[108,97]	6	hSpCas9	negative selection	1025215
33348627	33348650	11	+	26627737	GBM cells	viability after 21 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.49569516262406904	[247]	[105,85]	-4	hSpCas9	negative selection	1025216
33287316	33287339	11	-	26627737	RPE1	viability after 9 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.7056085008250722	[1527]	[601,1009]	5	hSpCas9	negative selection	1107526
33328592	33328615	11	+	26627737	RPE1	viability after 9 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	2.163185629303026	[142]	[210,186]	9	hSpCas9	negative selection	1107527
33347379	33347402	11	+	26627737	RPE1	viability after 9 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-1.197147868822742	[1501]	[215,190]	-7	hSpCas9	negative selection	1107528
33347612	33347635	11	+	26627737	RPE1	viability after 9 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	1.2114897437363354	[433]	[294,339]	7	hSpCas9	negative selection	1107529
33348179	33348202	11	+	26627737	RPE1	viability after 9 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	1.7748253419116333	[94]	[82,125]	8	hSpCas9	negative selection	1107530
33348627	33348650	11	+	26627737	RPE1	viability after 9 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.1833863111935533	[1198]	[423,209]	-1	hSpCas9	negative selection	1107531
33287316	33287339	11	-	26627737	RPE1	viability after 12 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.5655928012055488	[1527]	[456,766]	4	hSpCas9	negative selection	1189841
33328592	33328615	11	+	26627737	RPE1	viability after 12 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	2.2287800053439843	[142]	[267,86]	9	hSpCas9	negative selection	1189842
33347379	33347402	11	+	26627737	RPE1	viability after 12 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-1.1383822763311802	[1501]	[125,243]	-7	hSpCas9	negative selection	1189843
33347612	33347635	11	+	26627737	RPE1	viability after 12 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.7657892136410388	[433]	[155,242]	5	hSpCas9	negative selection	1189844
33348179	33348202	11	+	26627737	RPE1	viability after 12 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	1.5833742100380013	[94]	[41,112]	8	hSpCas9	negative selection	1189845
33348627	33348650	11	+	26627737	RPE1	viability after 12 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.24844316212690631	[1198]	[310,228]	-2	hSpCas9	negative selection	1189846
33287316	33287339	11	-	26627737	RPE1	viability after 15 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.44504115735719985	[1527]	[479,692]	3	hSpCas9	negative selection	1272156
33328592	33328615	11	+	26627737	RPE1	viability after 15 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	2.904943793246502	[142]	[472,138]	9	hSpCas9	negative selection	1272157
33347379	33347402	11	+	26627737	RPE1	viability after 15 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-1.24801647088657	[1501]	[128,226]	-7	hSpCas9	negative selection	1272158
33347612	33347635	11	+	26627737	RPE1	viability after 15 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	1.0599936260073075	[433]	[257,253]	6	hSpCas9	negative selection	1272159
33348179	33348202	11	+	26627737	RPE1	viability after 15 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.8530842280539894	[94]	[17,77]	5	hSpCas9	negative selection	1272160
33348627	33348650	11	+	26627737	RPE1	viability after 15 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.43973031422011666	[1198]	[330,171]	-3	hSpCas9	negative selection	1272161
33287316	33287339	11	-	26627737	RPE1	viability after 18 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.34585814791984537	[1527]	[496,552]	2	hSpCas9	negative selection	1354471
33328592	33328615	11	+	26627737	RPE1	viability after 18 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	2.5198326640995545	[142]	[259,179]	9	hSpCas9	negative selection	1354472
33347379	33347402	11	+	26627737	RPE1	viability after 18 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-1.9022375409796837	[1501]	[62,156]	-8	hSpCas9	negative selection	1354473
33347612	33347635	11	+	26627737	RPE1	viability after 18 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.8217361031108436	[433]	[192,221]	5	hSpCas9	negative selection	1354474
33348179	33348202	11	+	26627737	RPE1	viability after 18 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	1.3654494025925734	[94]	[23,110]	7	hSpCas9	negative selection	1354475
33348627	33348650	11	+	26627737	RPE1	viability after 18 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.7374710406049328	[1198]	[137,253]	-4	hSpCas9	negative selection	1354476
33287316	33287339	11	-	26627737	HeLa	viability after 8 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.24215527215244848	[1069]	[468,489,248]	-2	hSpCas9	negative selection	1436786
33328592	33328615	11	+	26627737	HeLa	viability after 8 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-1.2436518794581937	[647]	[128,45,179]	-8	hSpCas9	negative selection	1436787
33347379	33347402	11	+	26627737	HeLa	viability after 8 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.7851778793780205	[332]	[288,266,204]	6	hSpCas9	negative selection	1436788
33347612	33347635	11	+	26627737	HeLa	viability after 8 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.9759054115811623	[125]	[106,73,139]	7	hSpCas9	negative selection	1436789
33348179	33348202	11	+	26627737	HeLa	viability after 8 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.5000967544202504	[215]	[268,89,73]	4	hSpCas9	negative selection	1436790
33348627	33348650	11	+	26627737	HeLa	viability after 8 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.30725817659706545	[507]	[215,161,166]	-3	hSpCas9	negative selection	1436791
33287316	33287339	11	-	26627737	HeLa	viability after 12 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.13039513917452483	[1069]	[416,406,387]	-1	hSpCas9	negative selection	1519101
33328592	33328615	11	+	26627737	HeLa	viability after 12 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-1.7708420848607782	[647]	[58,95,77]	-9	hSpCas9	negative selection	1519102
33347379	33347402	11	+	26627737	HeLa	viability after 12 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.7652705940126199	[332]	[172,223,303]	6	hSpCas9	negative selection	1519103
33347612	33347635	11	+	26627737	HeLa	viability after 12 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-0.020521324808651986	[125]	[101,36,17]	0	hSpCas9	negative selection	1519104
33348179	33348202	11	+	26627737	HeLa	viability after 12 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.6987963581457198	[215]	[166,128,140]	5	hSpCas9	negative selection	1519105
33348627	33348650	11	+	26627737	HeLa	viability after 12 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-1.493578273098649	[507]	[75,118,23]	-8	hSpCas9	negative selection	1519106
33287316	33287339	11	-	26627737	HeLa	viability after 15 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.5913044781107123	[1069]	[196,340,333]	-5	hSpCas9	negative selection	1601416
33328592	33328615	11	+	26627737	HeLa	viability after 15 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-1.7083228792095009	[647]	[29,105,108]	-9	hSpCas9	negative selection	1601417
33347379	33347402	11	+	26627737	HeLa	viability after 15 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.5239882383871747	[332]	[181,267,129]	4	hSpCas9	negative selection	1601418
33347612	33347635	11	+	26627737	HeLa	viability after 15 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.12929256057364213	[125]	[14,119,31]	1	hSpCas9	negative selection	1601419
33348179	33348202	11	+	26627737	HeLa	viability after 15 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.48748820829764883	[215]	[183,122,56]	4	hSpCas9	negative selection	1601420
33348627	33348650	11	+	26627737	HeLa	viability after 15 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.3908174654969064	[507]	[319,54,90]	-3	hSpCas9	negative selection	1601421
33287316	33287339	11	-	26627737	HeLa	viability after 18 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.596614069111094	[1069]	[135,274,333]	-5	hSpCas9	negative selection	1683731
33328592	33328615	11	+	26627737	HeLa	viability after 18 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-1.676929548962503	[647]	[20,90,108]	-9	hSpCas9	negative selection	1683732
33347379	33347402	11	+	26627737	HeLa	viability after 18 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.5108214765843382	[332]	[120,218,129]	4	hSpCas9	negative selection	1683733
33347612	33347635	11	+	26627737	HeLa	viability after 18 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.1192774367493552	[125]	[7,100,31]	1	hSpCas9	negative selection	1683734
33348179	33348202	11	+	26627737	HeLa	viability after 18 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.4587123301248211	[215]	[112,108,56]	4	hSpCas9	negative selection	1683735
33348627	33348650	11	+	26627737	HeLa	viability after 18 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.35433655790062457	[507]	[222,44,90]	-3	hSpCas9	negative selection	1683736
33287316	33287339	11	-	26627737	HCT116	viability after 6 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-1.1528176010992894	[1102]	[28,104]	-6	hSpCas9	negative selection	1766046
33328592	33328615	11	+	26627737	HCT116	viability after 6 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-0.6247849563159515	[849]	[134,59]	-4	hSpCas9	negative selection	1766047
33347379	33347402	11	+	26627737	HCT116	viability after 6 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.4849398555177389	[1258]	[276,276]	2	hSpCas9	negative selection	1766048
33347612	33347635	11	+	26627737	HCT116	viability after 6 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	1.465051459768767	[277]	[61,152]	7	hSpCas9	negative selection	1766049
33348179	33348202	11	+	26627737	HCT116	viability after 6 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	-0.6558458505974596	[223]	[51,5]	-4	hSpCas9	negative selection	1766050
33348627	33348650	11	+	26627737	HCT116	viability after 6 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-1.2194778891695246	[669]	[119,3]	-6	hSpCas9	negative selection	1766051
33287316	33287339	11	-	26627737	HCT116	viability after 8 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.20882179716007865	[634]	[381,334,193]	-2	hSpCas9	negative selection	1848361
33328592	33328615	11	+	26627737	HCT116	viability after 8 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-0.18165615406229535	[369]	[137,176,222]	-2	hSpCas9	negative selection	1848362
33347379	33347402	11	+	26627737	HCT116	viability after 8 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.6697114776323836	[382]	[304,315,384]	6	hSpCas9	negative selection	1848363
33347612	33347635	11	+	26627737	HCT116	viability after 8 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.5741649193219523	[169]	[132,122,161]	6	hSpCas9	negative selection	1848364
33348179	33348202	11	+	26627737	HCT116	viability after 8 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	-0.20345114367889694	[157]	[76,85,63]	-2	hSpCas9	negative selection	1848365
33348627	33348650	11	+	26627737	HCT116	viability after 8 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.7581557305642638	[570]	[187,173,195]	-7	hSpCas9	negative selection	1848366
33287316	33287339	11	-	26627737	HCT116	viability after 9 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.3966721913490012	[1102]	[192,247]	-3	hSpCas9	negative selection	1930676
33328592	33328615	11	+	26627737	HCT116	viability after 9 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.24145637542406573	[849]	[312,232]	1	hSpCas9	negative selection	1930677
33347379	33347402	11	+	26627737	HCT116	viability after 9 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.10517322851744837	[1258]	[273,342]	0	hSpCas9	negative selection	1930678
33347612	33347635	11	+	26627737	HCT116	viability after 9 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.8413311741311509	[277]	[132,132]	6	hSpCas9	negative selection	1930679
33348179	33348202	11	+	26627737	HCT116	viability after 9 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	1.771397563719106	[223]	[44,329]	9	hSpCas9	negative selection	1930680
33348627	33348650	11	+	26627737	HCT116	viability after 9 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	0.807780127892673	[669]	[549,125]	6	hSpCas9	negative selection	1930681
33287316	33287339	11	-	26627737	HCT116	viability after 12 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.17580946968529876	[634]	[322,342,218]	-2	hSpCas9	negative selection	2012991
33328592	33328615	11	+	26627737	HCT116	viability after 12 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.24264146061001102	[369]	[208,228,253]	2	hSpCas9	negative selection	2012992
33347379	33347402	11	+	26627737	HCT116	viability after 12 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.0032159058004236907	[382]	[147,205,255]	0	hSpCas9	negative selection	2012993
33347612	33347635	11	+	26627737	HCT116	viability after 12 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.10914231527703011	[169]	[144,62,75]	1	hSpCas9	negative selection	2012994
33348179	33348202	11	+	26627737	HCT116	viability after 12 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.5209121884021837	[157]	[141,101,110]	5	hSpCas9	negative selection	2012995
33348627	33348650	11	+	26627737	HCT116	viability after 12 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-1.1199580180503532	[570]	[163,99,146]	-8	hSpCas9	negative selection	2012996
33287316	33287339	11	-	26627737	HCT116	viability after 15 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.39520247041212253	[634]	[263,349,216]	-4	hSpCas9	negative selection	2095306
33328592	33328615	11	+	26627737	HCT116	viability after 15 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.22666697781285672	[369]	[274,214,258]	2	hSpCas9	negative selection	2095307
33347379	33347402	11	+	26627737	HCT116	viability after 15 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.8890302781449786	[382]	[353,243,614]	7	hSpCas9	negative selection	2095308
33347612	33347635	11	+	26627737	HCT116	viability after 15 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.2515695236798109	[169]	[173,88,92]	2	hSpCas9	negative selection	2095309
33348179	33348202	11	+	26627737	HCT116	viability after 15 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.6208793819834828	[157]	[125,153,136]	5	hSpCas9	negative selection	2095310
33348627	33348650	11	+	26627737	HCT116	viability after 15 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.7888438232548967	[570]	[167,145,251]	-7	hSpCas9	negative selection	2095311
33287316	33287339	11	-	26627737	HCT116	viability after 18 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	-0.11977921959983673	[634]	[282,218,352]	-1	hSpCas9	negative selection	2177621
33328592	33328615	11	+	26627737	HCT116	viability after 18 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.1618180786784173	[369]	[156,134,317]	1	hSpCas9	negative selection	2177622
33347379	33347402	11	+	26627737	HCT116	viability after 18 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.8093250047138536	[382]	[263,215,508]	6	hSpCas9	negative selection	2177623
33347612	33347635	11	+	26627737	HCT116	viability after 18 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-0.42204415591380906	[169]	[69,57,55]	-4	hSpCas9	negative selection	2177624
33348179	33348202	11	+	26627737	HCT116	viability after 18 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.2716898671514354	[157]	[75,52,152]	2	hSpCas9	negative selection	2177625
33348627	33348650	11	+	26627737	HCT116	viability after 18 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.1362144317331241	[570]	[224,257,270]	-1	hSpCas9	negative selection	2177626
33286411	33286434	11	+	24336569	HL60	viability	AGGTATGGCCTCACAAGTCTTGG	HIPK3	ENSG00000110422	0.610652539922019	[574]	[1857]	5	hSpCas9	negative selection	2269702
33286419	33286442	11	-	24336569	HL60	viability	TGGGTAGACCAAGACTTGTGAGG	HIPK3	ENSG00000110422	0.23099479450106158	[427]	[1062]	2	hSpCas9	negative selection	2269703
33286442	33286465	11	-	24336569	HL60	viability	GACTGAGTTTGATAAACATATGG	HIPK3	ENSG00000110422	1.4675788258373172	[182]	[1070]	8	hSpCas9	negative selection	2269704
33286501	33286524	11	+	24336569	HL60	viability	GCCAAGCAGTTGTGTATTCCAGG	HIPK3	ENSG00000110422	-0.3148276397863476	[692]	[1178]	-3	hSpCas9	negative selection	2269705
33286518	33286541	11	+	24336569	HL60	viability	TCCAGGAAAGAAACTATCCACGG	HIPK3	ENSG00000110422	-0.6956804063251665	[136]	[178]	-6	hSpCas9	negative selection	2269706
33286532	33286555	11	+	24336569	HL60	viability	TATCCACGGACCTATGTGAATGG	HIPK3	ENSG00000110422	0.6679924377205066	[137]	[463]	6	hSpCas9	negative selection	2269707
33286542	33286565	11	-	24336569	HL60	viability	AAAGTTTCTACCATTCACATAGG	HIPK3	ENSG00000110422	0.6894635569101171	[910]	[3108]	6	hSpCas9	negative selection	2269708
33286567	33286590	11	+	24336569	HL60	viability	AAATTCTCATCCTCCCACTAAGG	HIPK3	ENSG00000110422	1.3923961918563856	[406]	[2260]	8	hSpCas9	negative selection	2269709
33286577	33286600	11	-	24336569	HL60	viability	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	0.21282791683366675	[642]	[1576]	2	hSpCas9	negative selection	2269710
33286610	33286633	11	+	24336569	HL60	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.3879117642989741	[532]	[861]	-3	hSpCas9	negative selection	2269711
33286411	33286434	11	+	24336569	KBM7	viability	AGGTATGGCCTCACAAGTCTTGG	HIPK3	ENSG00000110422	0.0035626365472862798	[951]	[2602]	0	hSpCas9	negative selection	2336879
33286419	33286442	11	-	24336569	KBM7	viability	TGGGTAGACCAAGACTTGTGAGG	HIPK3	ENSG00000110422	0.374487848321323	[445]	[1576]	3	hSpCas9	negative selection	2336880
33286442	33286465	11	-	24336569	KBM7	viability	GACTGAGTTTGATAAACATATGG	HIPK3	ENSG00000110422	0.7899772811594049	[337]	[1593]	7	hSpCas9	negative selection	2336881
33286501	33286524	11	+	24336569	KBM7	viability	GCCAAGCAGTTGTGTATTCCAGG	HIPK3	ENSG00000110422	-0.0861227374748827	[503]	[1294]	0	hSpCas9	negative selection	2336882
33286518	33286541	11	+	24336569	KBM7	viability	TCCAGGAAAGAAACTATCCACGG	HIPK3	ENSG00000110422	0.43212656973340546	[174]	[643]	4	hSpCas9	negative selection	2336883
33286532	33286555	11	+	24336569	KBM7	viability	TATCCACGGACCTATGTGAATGG	HIPK3	ENSG00000110422	0.3487580602789855	[168]	[586]	3	hSpCas9	negative selection	2336884
33286542	33286565	11	-	24336569	KBM7	viability	AAAGTTTCTACCATTCACATAGG	HIPK3	ENSG00000110422	0.7682695768529665	[583]	[2712]	7	hSpCas9	negative selection	2336885
33286567	33286590	11	+	24336569	KBM7	viability	AAATTCTCATCCTCCCACTAAGG	HIPK3	ENSG00000110422	0.2583356516583607	[525]	[1715]	2	hSpCas9	negative selection	2336886
33286577	33286600	11	-	24336569	KBM7	viability	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	0.050500925489352366	[672]	[1900]	0	hSpCas9	negative selection	2336887
33286610	33286633	11	+	24336569	KBM7	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.16983283048945186	[380]	[1168]	1	hSpCas9	negative selection	2336888
33323356	33323379	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTCAGCCTCCCAAGTAGCCGG	HIPK3	ENSG00000110422	0.6911400425855385	[25,30]	[5,13]	3	dCas9-VP64	positive selection	2396520
33258150	33258173	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGCGGGGGCCGTAGCCTCCGGG	HIPK3	ENSG00000110422	1.4639227871679446	[99,92]	[63,52]	5	dCas9-VP64	positive selection	2419595
33258176	33258199	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCCGGGCCCCGGCCAGGCGCGG	HIPK3	ENSG00000110422	0.38603201411649224	[117,10]	[5,30]	1	dCas9-VP64	positive selection	2419596
33258221	33258244	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGAGCCGTTGCGCAACCTTGG	HIPK3	ENSG00000110422	3.0815356607575795	[20,108]	[28,223]	8	dCas9-VP64	positive selection	2419597
33270172	33270195	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCATGTTAGCCAGGCCGG	HIPK3	ENSG00000110422	0.14297587756234287	[48,62]	[20,4]	0	dCas9-VP64	positive selection	2422701
33311882	33311905	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTTGCTATGTTGCCCAAG	HIPK3	ENSG00000110422	0.7258925451918798	[40,76]	[27,13]	3	dCas9-VP64	positive selection	2423505
33257199	33257222	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACAAGGGCGCGGCTGCGGACTGG	HIPK3	ENSG00000110422	0.29747535218693866	[18,28]	[6,4]	1	dCas9-VP64	positive selection	2438520
33257146	33257169	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTTGCGGGACTCCGGGTTGGGG	HIPK3	ENSG00000110422	-0.507695721813364	[19,65]	[2,8]	-2	dCas9-VP64	positive selection	2438521
33257124	33257147	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCTTCTTTCGCGGGAGGCTTGG	HIPK3	ENSG00000110422	-1.42435097263093	[112,244]	[6,21]	-7	dCas9-VP64	positive selection	2438522
33263388	33263411	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCCGCCTCCGGG	HIPK3	ENSG00000110422	-1.3762222380081446	[352,174]	[18,24]	-7	dCas9-VP64	positive selection	2454242
33283232	33283255	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCGAGTAGCTGGGACTATAAG	HIPK3	ENSG00000110422	-1.652200712598355	[99,148]	[10,4]	-8	dCas9-VP64	positive selection	2460211
33323356	33323379	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTCAGCCTCCCAAGTAGCCGG	HIPK3	ENSG00000110422	0.4030393266100577	[90,274]	[19,131]	3	dCas9-VP64	positive selection	2491775
33258150	33258173	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGCGGGGGCCGTAGCCTCCGGG	HIPK3	ENSG00000110422	-1.037829798992171	[221,155]	[33,25]	-8	dCas9-VP64	positive selection	2514850
33258176	33258199	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCCGGGCCCCGGCCAGGCGCGG	HIPK3	ENSG00000110422	1.2024305624650569	[45,12]	[31,12]	7	dCas9-VP64	positive selection	2514851
33258221	33258244	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGAGCCGTTGCGCAACCTTGG	HIPK3	ENSG00000110422	0.7062236777974524	[60,26]	[22,23]	5	dCas9-VP64	positive selection	2514852
33270172	33270195	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCATGTTAGCCAGGCCGG	HIPK3	ENSG00000110422	-0.3207422866751098	[290,27]	[45,37]	-3	dCas9-VP64	positive selection	2517956
33311882	33311905	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTTGCTATGTTGCCCAAG	HIPK3	ENSG00000110422	-0.28323094604648114	[112,110]	[38,20]	-3	dCas9-VP64	positive selection	2518760
33257199	33257222	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACAAGGGCGCGGCTGCGGACTGG	HIPK3	ENSG00000110422	-0.799613615977013	[193,45]	[16,27]	-7	dCas9-VP64	positive selection	2533775
33257146	33257169	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTTGCGGGACTCCGGGTTGGGG	HIPK3	ENSG00000110422	0.0631698090636959	[23,146]	[3,51]	0	dCas9-VP64	positive selection	2533776
33257124	33257147	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCTTCTTTCGCGGGAGGCTTGG	HIPK3	ENSG00000110422	0.4518650727689173	[186,162]	[32,119]	3	dCas9-VP64	positive selection	2533777
33263388	33263411	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCCGCCTCCGGG	HIPK3	ENSG00000110422	-1.0610924962734893	[123,419]	[26,55]	-8	dCas9-VP64	positive selection	2549497
33283232	33283255	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCGAGTAGCTGGGACTATAAG	HIPK3	ENSG00000110422	-0.7864950913442017	[144,106]	[22,23]	-7	dCas9-VP64	positive selection	2555466
33286411	33286434	11	+	27013184	SW480	treatment with recombinant TRAIL	AGGTATGGCCTCACAAGTCTTGG	HIPK3	ENSG00000110422	-5.0758209222554855	[138,176]	[1,1]	-9	hSpCas9	positive selection	2957527
33286501	33286524	11	+	27013184	SW480	treatment with recombinant TRAIL	GCCAAGCAGTTGTGTATTCCAGG	HIPK3	ENSG00000110422	-1.965241541879441	[35,101]	[3,11]	-7	hSpCas9	positive selection	2957528
33286728	33286751	11	+	27013184	SW480	treatment with recombinant TRAIL	AGGCACCTCAGATTGGGGCGTGG	HIPK3	ENSG00000110422	-4.959489280545413	[145,234]	[2,1]	-9	hSpCas9	positive selection	2957529
33328609	33328632	11	-	27013184	SW480	treatment with recombinant TRAIL	GATCATACTCCAAGGCTCCTGGG	HIPK3	ENSG00000110422	0.23528999591030608	[880,1323]	[398,764]	1	hSpCas9	positive selection	2957530
33328610	33328633	11	-	27013184	SW480	treatment with recombinant TRAIL	TGATCATACTCCAAGGCTCCTGG	HIPK3	ENSG00000110422	-1.3033278487631912	[129,287]	[24,49]	-6	hSpCas9	positive selection	2957531
33328617	33328640	11	-	27013184	SW480	treatment with recombinant TRAIL	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	1.5319917732355581	[436,670]	[691,658]	7	hSpCas9	positive selection	2957532
33286518	33286541	11	+	27013184	SW480	treatment with recombinant TRAIL	TCCAGGAAAGAAACTATCCACGG	HIPK3	ENSG00000110422	0.2417902733765329	[191,166]	[125,43]	1	hSpCas9	positive selection	2957533
33287023	33287046	11	+	27013184	SW480	treatment with recombinant TRAIL	TGGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.59622174335289	[475,508]	[302,344]	3	hSpCas9	positive selection	2957534
33287105	33287128	11	+	27013184	SW480	treatment with recombinant TRAIL	CATCCTTCTTATGCCCGTCAAGG	HIPK3	ENSG00000110422	-0.09166786212677391	[90,206]	[49,69]	0	hSpCas9	positive selection	2957535
33287409	33287432	11	+	27013184	SW480	treatment with recombinant TRAIL	ATCCTGTTCGGCAGCCTTACAGG	HIPK3	ENSG00000110422	0.3688372225172941	[283,299]	[125,213]	2	hSpCas9	positive selection	2957536
33287410	33287433	11	+	27013184	SW480	treatment with recombinant TRAIL	TCCTGTTCGGCAGCCTTACAGGG	HIPK3	ENSG00000110422	1.988216592283142	[111,45]	[46,272]	8	hSpCas9	positive selection	2957537
33286532	33286555	11	+	27013184	SW480	treatment with recombinant TRAIL	TATCCACGGACCTATGTGAATGG	HIPK3	ENSG00000110422	-0.1630345822709569	[35,33]	[15,9]	0	hSpCas9	positive selection	2957538
33286419	33286442	11	-	27013184	SW480	treatment with recombinant TRAIL	TGGGTAGACCAAGACTTGTGAGG	HIPK3	ENSG00000110422	-0.6327307275727595	[179,188]	[23,89]	-3	hSpCas9	positive selection	2957539
33286470	33286493	11	-	27013184	SW480	treatment with recombinant TRAIL	GAGTTTCTTCACACTACAAAAGG	HIPK3	ENSG00000110422	1.1110762158750571	[1,11]	[8,1]	5	hSpCas9	positive selection	2957540
33286502	33286525	11	-	27013184	SW480	treatment with recombinant TRAIL	TCCTGGAATACACAACTGCTTGG	HIPK3	ENSG00000110422	-0.619940716645786	[386,335]	[116,80]	-3	hSpCas9	positive selection	2957541
33286535	33286558	11	-	27013184	SW480	treatment with recombinant TRAIL	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	0.022757638116935652	[620,721]	[291,292]	0	hSpCas9	positive selection	2957542
33286542	33286565	11	-	27013184	SW480	treatment with recombinant TRAIL	AAAGTTTCTACCATTCACATAGG	HIPK3	ENSG00000110422	0.4367564166359319	[500,636]	[301,366]	2	hSpCas9	positive selection	2957543
33286577	33286600	11	-	27013184	SW480	treatment with recombinant TRAIL	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	0.6583557942698668	[238,311]	[177,195]	3	hSpCas9	positive selection	2957544
33286580	33286603	11	-	27013184	SW480	treatment with recombinant TRAIL	TGAAAAGCACTACCCTTAGTGGG	HIPK3	ENSG00000110422	1.3616657498059874	[222,261]	[344,155]	6	hSpCas9	positive selection	2957545
33286581	33286604	11	-	27013184	SW480	treatment with recombinant TRAIL	CTGAAAAGCACTACCCTTAGTGG	HIPK3	ENSG00000110422	0.15101058786332233	[171,163]	[19,166]	0	hSpCas9	positive selection	2957546
33286568	33286591	11	+	27013184	SW480	treatment with recombinant TRAIL	AATTCTCATCCTCCCACTAAGGG	HIPK3	ENSG00000110422	1.4814156736695472	[393,462]	[342,753]	6	hSpCas9	positive selection	2957547
33286625	33286648	11	-	27013184	SW480	treatment with recombinant TRAIL	AATGAAAAGTTGTGTCCTCGAGG	HIPK3	ENSG00000110422	0.669266004256609	[55,42]	[2,78]	3	hSpCas9	positive selection	2957548
33286780	33286803	11	-	27013184	SW480	treatment with recombinant TRAIL	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.2634350461619088	[452,426]	[211,251]	1	hSpCas9	positive selection	2957549
33286610	33286633	11	+	27013184	SW480	treatment with recombinant TRAIL	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.5919127982173176	[89,115]	[10,54]	-3	hSpCas9	positive selection	2957550
33287011	33287034	11	-	27013184	SW480	treatment with recombinant TRAIL	TGCCTCGACCAAGAAAATCAAGG	HIPK3	ENSG00000110422	-0.28334035168424626	[122,276]	[58,81]	-1	hSpCas9	positive selection	2957551
33287041	33287064	11	-	27013184	SW480	treatment with recombinant TRAIL	TTTTCCAGCATTTAACTACCTGG	HIPK3	ENSG00000110422	-2.376471765305224	[42,78]	[6,1]	-8	hSpCas9	positive selection	2957552
33328592	33328615	11	+	27013184	SW480	treatment with recombinant TRAIL	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	1.7049248568662239	[402,738]	[927,574]	7	hSpCas9	positive selection	2957553
33328600	33328623	11	+	27013184	SW480	treatment with recombinant TRAIL	GCCGCTCTACCCAGGAGCCTTGG	HIPK3	ENSG00000110422	-0.3981103574724767	[458,347]	[115,158]	-2	hSpCas9	positive selection	2957554
33286687	33286710	11	+	27013184	SW480	treatment with recombinant TRAIL	TACAAAGGTCATAGCAGCTCAGG	HIPK3	ENSG00000110422	0.32252726424126554	[276,337]	[109,241]	1	hSpCas9	positive selection	2957555
33328612	33328635	11	+	27013184	SW480	treatment with recombinant TRAIL	AGGAGCCTTGGAGTATGATCAGG	HIPK3	ENSG00000110422	1.5487862717062681	[151,168]	[185,223]	7	hSpCas9	positive selection	2957556
33286577	33286600	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	-0.37287711325200096	[2,2]	[3,0]	-5	hSpCas9	positive selection	2993278
33287495	33287518	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.1323841515076592	[5,5]	[4,4]	2	hSpCas9	positive selection	2993279
33286535	33286558	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	0.013878131963417181	[2,3]	[2,2]	0	hSpCas9	positive selection	2993280
33286869	33286892	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAATGTTGCAAACCAACATGGG	HIPK3	ENSG00000110422	0.47511527349235905	[3,2]	[5,2]	8	hSpCas9	positive selection	2993281
33286577	33286600	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	0.27500426563624125	[2,2]	[2,2]	5	hSpCas9	positive selection	3061136
33287495	33287518	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.5357263605604254	[5,5]	[5,4]	8	hSpCas9	positive selection	3061137
33286535	33286558	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	0.5088674192636571	[2,2]	[3,2]	8	hSpCas9	positive selection	3061138
33286869	33286892	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAATGTTGCAAACCAACATGGG	HIPK3	ENSG00000110422	0.6967479324882413	[3,3]	[3,3]	9	hSpCas9	positive selection	3061139
33286610	33286633		+	24336571	A375	resistance to PLX after 7 days	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.29736609233652034	[13,18]	[17,21]	7	hSpCas9	positive selection	3119053
33286721	33286744		+	24336571	A375	resistance to PLX after 7 days	CACGTGCAGGCACCTCAGATTGG	HIPK3	ENSG00000110422	0.04142370337052359	[33,30]	[31,33]	1	hSpCas9	positive selection	3119054
33328617	33328640		-	24336571	A375	resistance to PLX after 7 days	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.22157733460687645	[17,18]	[22,19]	6	hSpCas9	positive selection	3119055
33286610	33286633		+	24336571	A375	resistance to PLX after 14 days	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.9488366048328077	[17,19]	[24,9]	7	hSpCas9	positive selection	3176846
33286721	33286744		+	24336571	A375	resistance to PLX after 14 days	CACGTGCAGGCACCTCAGATTGG	HIPK3	ENSG00000110422	0.4270526268785575	[31,28]	[17,19]	4	hSpCas9	positive selection	3176847
33328617	33328640		-	24336571	A375	resistance to PLX after 14 days	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	2.2281261558870495	[13,15]	[36,29]	9	hSpCas9	positive selection	3176848
33286610	33286633		+	24336571	A375	viability after 7 days	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.7649241441399238	[28]	[13,18]	-8	hSpCas9	negative selection	3234639
33286721	33286744		+	24336571	A375	viability after 7 days	CACGTGCAGGCACCTCAGATTGG	HIPK3	ENSG00000110422	0.3597619842962625	[25]	[33,30]	5	hSpCas9	negative selection	3234640
33328617	33328640		-	24336571	A375	viability after 7 days	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.7763201740952553	[33]	[17,18]	-8	hSpCas9	negative selection	3234641
33286610	33286633		+	24336571	A375	viability after 14 days	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.5125922868144289	[28]	[17,19]	-6	hSpCas9	negative selection	3292432
33286721	33286744		+	24336571	A375	viability after 14 days	CACGTGCAGGCACCTCAGATTGG	HIPK3	ENSG00000110422	0.29125987829652744	[25]	[31,28]	4	hSpCas9	negative selection	3292433
33328617	33328640		-	24336571	A375	viability after 14 days	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-1.048161377617778	[33]	[13,15]	-8	hSpCas9	negative selection	3292434
33286610	33286633	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	3.17041814622267	[15,17]	[0,0]	8	hSpCas9	positive selection	3353413
33286780	33286803	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.9491295771483115	[277,312]	[0,0]	-6	hSpCas9	positive selection	3353414
33337078	33337101	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.6508181804434143	[88,105]	[0,0]	3	hSpCas9	positive selection	3353415
33328617	33328640	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-2.5723965236402235	[909,909]	[0,0]	-9	hSpCas9	positive selection	3372616
33337107	33337130	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.3049162127752376	[188,188]	[0,0]	-2	hSpCas9	positive selection	3372617
33328514	33328537	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.25732621144583506	[127,127]	[0,0]	1	hSpCas9	positive selection	3372618
33286577	33286600	11	-	26780180	HT29	viability (Avana library 4 designs)	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	1.12206180714119	[]	[]	4	hSpCas9	negative selection	3430539
33287494	33287517	11	+	26780180	HT29	viability (Avana library 4 designs)	ACAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	-0.754122776577382	[]	[]	-8	hSpCas9	negative selection	3430540
33286535	33286558	11	-	26780180	HT29	viability (Avana library 4 designs)	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	0.846808470859924	[]	[]	3	hSpCas9	negative selection	3430541
33286868	33286891	11	+	26780180	HT29	viability (Avana library 4 designs)	GCAATGTTGCAAACCAACATGGG	HIPK3	ENSG00000110422	0.412982190365009	[]	[]	1	hSpCas9	negative selection	3430542
33286535	33286558	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	4.99304932726193	[]	[]	8	hSpCas9	negative selection	3515751
33286868	33286891	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAATGTTGCAAACCAACATGGG	HIPK3	ENSG00000110422	-0.0700100484709443	[]	[]	0	hSpCas9	negative selection	3515752
33286577	33286600	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	3.2777370100419	[]	[]	5	hSpCas9	negative selection	3515753
33287494	33287517	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	-3.27429195664597	[]	[]	-4	hSpCas9	negative selection	3515754
33328609	33328632	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATCATACTCCAAGGCTCCTGGG	HIPK3	ENSG00000110422	-0.181954045071773	[]	[]	0	hSpCas9	negative selection	3515755
33286777	33286800	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCAATCCACATCGCTGGGGG	HIPK3	ENSG00000110422	-0.938497374368715	[]	[]	-1	hSpCas9	negative selection	3515756
33286535	33286558	11	-	26780180	A375	viability (Avana lentiGuide)	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	-2.23937339617345	[]	[]	-4	hSpCas9	negative selection	3624410
33286868	33286891	11	+	26780180	A375	viability (Avana lentiGuide)	GCAATGTTGCAAACCAACATGGG	HIPK3	ENSG00000110422	1.31603577636215	[]	[]	1	hSpCas9	negative selection	3624411
33286577	33286600	11	-	26780180	A375	viability (Avana lentiGuide)	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	0.404129878194521	[]	[]	0	hSpCas9	negative selection	3624412
33287494	33287517	11	+	26780180	A375	viability (Avana lentiGuide)	ACAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	2.42800098511594	[]	[]	2	hSpCas9	negative selection	3624413
33328609	33328632	11	-	26780180	A375	viability (Avana lentiGuide)	GATCATACTCCAAGGCTCCTGGG	HIPK3	ENSG00000110422	-5.32992242845136	[]	[]	-8	hSpCas9	negative selection	3624414
33286777	33286800	11	-	26780180	A375	viability (Avana lentiGuide)	GCTTCAATCCACATCGCTGGGGG	HIPK3	ENSG00000110422	-3.67681821336467	[]	[]	-6	hSpCas9	negative selection	3624415
33286535	33286558	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	0.19092361306050282	[5]	[6,5]	5	hSpCas9	positive selection	3733069
33286868	33286891	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAATGTTGCAAACCAACATGGG	HIPK3	ENSG00000110422	-0.2708419178671317	[4]	[3,2]	-4	hSpCas9	positive selection	3733070
33286577	33286600	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	-0.0029085618931891377	[4]	[3,4]	0	hSpCas9	positive selection	3733071
33287494	33287517	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.01820471478403768	[6]	[6,6]	0	hSpCas9	positive selection	3733072
33328609	33328632	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATCATACTCCAAGGCTCCTGGG	HIPK3	ENSG00000110422	-0.03747330885790308	[5]	[5,4]	0	hSpCas9	positive selection	3733073
33286777	33286800	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCAATCCACATCGCTGGGGG	HIPK3	ENSG00000110422	-0.24024359618199886	[4]	[3,3]	-4	hSpCas9	positive selection	3733074
33286535	33286558	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCATTCACATAGGTCCGTGG	HIPK3	ENSG00000110422	-0.016958561687653737	[5]	[2,5]	0	hSpCas9	positive selection	3841676
33286868	33286891	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAATGTTGCAAACCAACATGGG	HIPK3	ENSG00000110422	-0.40257244374317364	[4]	[2,2]	-5	hSpCas9	positive selection	3841677
33286577	33286600	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAAGCACTACCCTTAGTGGGAGG	HIPK3	ENSG00000110422	-0.30025133318352937	[4]	[4,0]	-4	hSpCas9	positive selection	3841678
33287494	33287517	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.26833743679885	[7]	[7,7]	7	hSpCas9	positive selection	3841679
33328609	33328632	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATCATACTCCAAGGCTCCTGGG	HIPK3	ENSG00000110422	0.280625847069086	[6]	[6,5]	7	hSpCas9	positive selection	3841680
33286777	33286800	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCAATCCACATCGCTGGGGG	HIPK3	ENSG00000110422	0.23994004996265542	[4]	[4,5]	6	hSpCas9	positive selection	3841681
33337107	33337130	11	+	26780180	A375	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.505388220756861	[]	[]	1	hSpCas9	negative selection	3947750
33286610	33286633	11	+	26780180	A375	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.784364474039683	[]	[]	3	hSpCas9	negative selection	3947751
33337078	33337101	11	+	26780180	A375	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	1.08162806939068	[]	[]	5	hSpCas9	negative selection	3947752
33328514	33328537	11	-	26780180	A375	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	1.52715489466146	[]	[]	8	hSpCas9	negative selection	3947753
33286780	33286803	11	-	26780180	A375	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	1.21447174407997	[]	[]	6	hSpCas9	negative selection	3947754
33328617	33328640	11	-	26780180	A375	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.15579462499132	[]	[]	0	hSpCas9	negative selection	3947755
33337107	33337130	11	+	26780180	HT29	viability (GeCKOv2 library)	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.534362753923752	[]	[]	1	hSpCas9	negative selection	4055716
33286610	33286633	11	+	26780180	HT29	viability (GeCKOv2 library)	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	1.17306249449734	[]	[]	5	hSpCas9	negative selection	4055717
33337078	33337101	11	+	26780180	HT29	viability (GeCKOv2 library)	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.317937448293056	[]	[]	0	hSpCas9	negative selection	4055718
33328514	33328537	11	-	26780180	HT29	viability (GeCKOv2 library)	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	1.50493417022866	[]	[]	7	hSpCas9	negative selection	4055719
33286780	33286803	11	-	26780180	HT29	viability (GeCKOv2 library)	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	1.13572753256111	[]	[]	5	hSpCas9	negative selection	4055720
33328617	33328640	11	-	26780180	HT29	viability (GeCKOv2 library)	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.0278860398378545	[]	[]	0	hSpCas9	negative selection	4055721
33286610	33286633	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.27130655937136655	[3]	[2,3]	6	hSpCas9	positive selection	4142535
33286721	33286744	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACGTGCAGGCACCTCAGATTGG	HIPK3	ENSG00000110422	0.25167524000330177	[4]	[3,4]	6	hSpCas9	positive selection	4142536
33328617	33328640	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.5276713715824992	[3]	[2,5]	9	hSpCas9	positive selection	4142537
33286610	33286633	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.33451331960505515	[4]	[2,4,5,0]	2	hSpCas9	positive selection	4206557
33286721	33286744	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACGTGCAGGCACCTCAGATTGG	HIPK3	ENSG00000110422	1.0478989525165556	[4]	[4,4,3,3]	7	hSpCas9	positive selection	4206558
33328617	33328640	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	1.1604654810452117	[4]	[2,4,6,3]	8	hSpCas9	positive selection	4206559
33286610	33286633	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.2786540824327619	[1]	[1,0]	-5	hSpCas9	positive selection	4275024
33286780	33286803	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.11170966664128373	[4]	[3,3]	2	hSpCas9	positive selection	4275025
33337078	33337101	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.011999395625771347	[2]	[2,0]	0	hSpCas9	positive selection	4275026
33328617	33328640	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.3194427009012272	[4]	[4,4]	6	hSpCas9	positive selection	4339285
33337107	33337130	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.20052354524754434	[3]	[3,2]	4	hSpCas9	positive selection	4339286
33328514	33328537	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.0037876230068076278	[2]	[2,0]	0	hSpCas9	positive selection	4339287
33286611	33286633	11	+	27760321	OCIAML3	viability	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.024654505340511612	[153,100]	[40,176]	0	hSpCas9	negative selection	4406938
33286780	33286802	11	-	27760321	OCIAML3	viability	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.024160046784248435	[907,795]	[527,817]	0	hSpCas9	negative selection	4406939
33287024	33287046	11	+	27760321	OCIAML3	viability	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.16039465469185765	[708,556]	[431,702]	1	hSpCas9	negative selection	4406940
33287293	33287315	11	-	27760321	OCIAML3	viability	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	-0.24618930619411372	[811,698]	[392,631]	-3	hSpCas9	negative selection	4406941
33287495	33287517	11	+	27760321	OCIAML3	viability	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	-0.11521914434068012	[582,514]	[284,539]	-1	hSpCas9	negative selection	4406942
33286611	33286633	11	+	27760321	OCIAML2	viability	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-1.4166238491865364	[153,100]	[22,57]	-8	hSpCas9	negative selection	4490401
33286780	33286802	11	-	27760321	OCIAML2	viability	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.35548987201027626	[907,795]	[474,619]	-4	hSpCas9	negative selection	4490402
33287024	33287046	11	+	27760321	OCIAML2	viability	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.23926068356126173	[708,556]	[489,745]	3	hSpCas9	negative selection	4490403
33287293	33287315	11	-	27760321	OCIAML2	viability	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	-0.24608023348444585	[811,698]	[471,568]	-3	hSpCas9	negative selection	4490404
33287495	33287517	11	+	27760321	OCIAML2	viability	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.23883584626796173	[582,514]	[419,658]	3	hSpCas9	negative selection	4490405
33286611	33286633	11	+	27760321	MV411	viability	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	1.013578257548065	[153,100]	[77,301]	7	hSpCas9	negative selection	4573864
33286780	33286802	11	-	27760321	MV411	viability	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.08701010849085455	[907,795]	[507,727]	0	hSpCas9	negative selection	4573865
33287024	33287046	11	+	27760321	MV411	viability	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.7110308550413531	[708,556]	[797,500]	5	hSpCas9	negative selection	4573866
33287293	33287315	11	-	27760321	MV411	viability	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	0.08274355871511718	[811,698]	[619,385]	0	hSpCas9	negative selection	4573867
33287495	33287517	11	+	27760321	MV411	viability	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	1.0272623833988233	[582,514]	[573,981]	7	hSpCas9	negative selection	4573868
33286611	33286633	11	+	27760321	HL60	viability	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.06819034839112659	[153,100]	[63,133]	-1	hSpCas9	negative selection	4657327
33286780	33286802	11	-	27760321	HL60	viability	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.021884696425320316	[907,795]	[602,769]	0	hSpCas9	negative selection	4657328
33287024	33287046	11	+	27760321	HL60	viability	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.2488244799455438	[708,556]	[506,719]	3	hSpCas9	negative selection	4657329
33287293	33287315	11	-	27760321	HL60	viability	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	-0.2512878032010397	[811,698]	[500,533]	-3	hSpCas9	negative selection	4657330
33287495	33287517	11	+	27760321	HL60	viability	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.6416753042176166	[582,514]	[711,683]	7	hSpCas9	negative selection	4657331
33286611	33286633	11	+	27760321	HT1080	viability	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.2591072019931393	[100,78]	[19,67]	1	hSpCas9	negative selection	4740790
33286780	33286802	11	-	27760321	HT1080	viability	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.9851597147621316	[795,620]	[583,530]	5	hSpCas9	negative selection	4740791
33287024	33287046	11	+	27760321	HT1080	viability	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.4152887945933506	[556,434]	[189,343]	2	hSpCas9	negative selection	4740792
33287293	33287315	11	-	27760321	HT1080	viability	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	0.44301373160999846	[698,545]	[318,356]	2	hSpCas9	negative selection	4740793
33287495	33287517	11	+	27760321	HT1080	viability	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.9066994693410043	[514,401]	[477,193]	5	hSpCas9	negative selection	4740794
33286611	33286633	11	+	27760321	HT29	viability after 7 days	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.14684546152403577	[100,78]	[128,84,168]	2	hSpCas9	negative selection	4824253
33286780	33286802	11	-	27760321	HT29	viability after 7 days	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.06430130851435911	[795,620]	[1028,986,853]	1	hSpCas9	negative selection	4824254
33287024	33287046	11	+	27760321	HT29	viability after 7 days	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.36517177159624553	[556,434]	[699,517,1214]	5	hSpCas9	negative selection	4824255
33287293	33287315	11	-	27760321	HT29	viability after 7 days	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	-0.5955501660331128	[698,545]	[587,426,579]	-7	hSpCas9	negative selection	4824256
33287495	33287517	11	+	27760321	HT29	viability after 7 days	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.3454400587886405	[514,401]	[907,752,611]	5	hSpCas9	negative selection	4824257
33286611	33286633	11	+	27760321	HT29	viability after 25 days	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.5687840874383481	[100,78]	[173,130,150]	6	hSpCas9	negative selection	4907716
33286780	33286802	11	-	27760321	HT29	viability after 25 days	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.0749592735458926	[795,620]	[706,863,1011]	0	hSpCas9	negative selection	4907717
33287024	33287046	11	+	27760321	HT29	viability after 25 days	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	1.138931932936217	[556,434]	[1190,1080,1500]	9	hSpCas9	negative selection	4907718
33287293	33287315	11	-	27760321	HT29	viability after 25 days	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	0.37014776415879536	[698,545]	[872,985,898]	4	hSpCas9	negative selection	4907719
33287495	33287517	11	+	27760321	HT29	viability after 25 days	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.9697661574286754	[514,401]	[1040,1105,917]	9	hSpCas9	negative selection	4907720
33286611	33286633	11	+	27760321	HT29	viability after 22 days	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.5500986681532658	[100,78]	[159,130,165]	6	hSpCas9	negative selection	4991179
33286780	33286802	11	-	27760321	HT29	viability after 22 days	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.20055039893728044	[795,620]	[745,605,785]	-2	hSpCas9	negative selection	4991180
33287024	33287046	11	+	27760321	HT29	viability after 22 days	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.811153824572248	[556,434]	[1191,746,1074]	8	hSpCas9	negative selection	4991181
33287293	33287315	11	-	27760321	HT29	viability after 22 days	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	0.45420299980303414	[698,545]	[1065,979,908]	5	hSpCas9	negative selection	4991182
33287495	33287517	11	+	27760321	HT29	viability after 22 days	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.96576021678833	[514,401]	[1046,1061,995]	9	hSpCas9	negative selection	4991183
33286611	33286633	11	+	27760321	HT29	viability after 19 days	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.17002526453130318	[100,78]	[93,78,169]	1	hSpCas9	negative selection	5074642
33286780	33286802	11	-	27760321	HT29	viability after 19 days	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.34650718183316065	[795,620]	[920,869,1277]	3	hSpCas9	negative selection	5074643
33287024	33287046	11	+	27760321	HT29	viability after 19 days	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	1.1616796138607746	[556,434]	[1020,859,1875]	9	hSpCas9	negative selection	5074644
33287293	33287315	11	-	27760321	HT29	viability after 19 days	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	0.11586540065665674	[698,545]	[528,729,1019]	1	hSpCas9	negative selection	5074645
33287495	33287517	11	+	27760321	HT29	viability after 19 days	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	1.036635640808682	[514,401]	[964,1096,1149]	9	hSpCas9	negative selection	5074646
33286611	33286633	11	+	27760321	HT29	viability after 16 days	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.14384871461145643	[100,78]	[172,57,109]	1	hSpCas9	negative selection	5158105
33286780	33286802	11	-	27760321	HT29	viability after 16 days	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.05991061066265335	[795,620]	[979,639,684]	0	hSpCas9	negative selection	5158106
33287024	33287046	11	+	27760321	HT29	viability after 16 days	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	1.1085573449743462	[556,434]	[1065,942,1574]	9	hSpCas9	negative selection	5158107
33287293	33287315	11	-	27760321	HT29	viability after 16 days	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	0.30102913934811215	[698,545]	[720,673,1170]	3	hSpCas9	negative selection	5158108
33287495	33287517	11	+	27760321	HT29	viability after 16 days	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	1.02363330222299	[514,401]	[1355,1046,754]	9	hSpCas9	negative selection	5158109
33286611	33286633	11	+	27760321	HT29	viability after 13 days	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.6665130250788835	[100,78]	[191,136,167]	8	hSpCas9	negative selection	5241568
33286780	33286802	11	-	27760321	HT29	viability after 13 days	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.039075388887082285	[795,620]	[917,853,765]	0	hSpCas9	negative selection	5241569
33287024	33287046	11	+	27760321	HT29	viability after 13 days	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.6760417830777523	[556,434]	[987,988,788]	8	hSpCas9	negative selection	5241570
33287293	33287315	11	-	27760321	HT29	viability after 13 days	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	0.014546826421067305	[698,545]	[588,720,869]	0	hSpCas9	negative selection	5241571
33287495	33287517	11	+	27760321	HT29	viability after 13 days	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.28623557851703774	[514,401]	[556,756,632]	3	hSpCas9	negative selection	5241572
33286611	33286633	11	+	27760321	HT29	viability after 10 days	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.7894497067229831	[100,78]	[178,286,120]	9	hSpCas9	negative selection	5325031
33286780	33286802	11	-	27760321	HT29	viability after 10 days	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.06474017853640857	[795,620]	[702,1056,1016]	0	hSpCas9	negative selection	5325032
33287024	33287046	11	+	27760321	HT29	viability after 10 days	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	0.9324265711769752	[556,434]	[1143,985,1404]	9	hSpCas9	negative selection	5325033
33287293	33287315	11	-	27760321	HT29	viability after 10 days	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	-0.11995992347413997	[698,545]	[1051,591,502]	-1	hSpCas9	negative selection	5325034
33287495	33287517	11	+	27760321	HT29	viability after 10 days	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	0.27336994933011427	[514,401]	[825,559,685]	3	hSpCas9	negative selection	5325035
33286611	33286633	11	+	27760321	MOLM13	viability	TACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	3.033511503387555	[153,100]	[1227,29]	9	hSpCas9	negative selection	5408494
33286780	33286802	11	-	27760321	MOLM13	viability	GCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-1.0446262461725915	[907,795]	[184,272]	-6	hSpCas9	negative selection	5408495
33287024	33287046	11	+	27760321	MOLM13	viability	GGTCGAGGCACGTTTGGCCAGG	HIPK3	ENSG00000110422	1.274458500557316	[708,556]	[1728,116]	8	hSpCas9	negative selection	5408496
33287293	33287315	11	-	27760321	MOLM13	viability	CCGAATCACTTTTAGTGGCAGG	HIPK3	ENSG00000110422	-0.21691593787294094	[811,698]	[436,304]	-1	hSpCas9	negative selection	5408497
33287495	33287517	11	+	27760321	MOLM13	viability	CAATCTCGGTACTACAGGTAGG	HIPK3	ENSG00000110422	1.3731493726629282	[582,514]	[734,856]	8	hSpCas9	negative selection	5408498
33257340	33257363	11	+	27661255	K562	viability	GGCCGACGAGCGCGGAGGAGGGG	HIPK3	ENSG00000110422	0.5782658377081147	[174,276]	[336,207]	9	dCas9-KRAB	negative selection	5484692
33257674	33257697	11	+	27661255	K562	viability	GCAGCAGCAGCAGCGGTCGGGGG	HIPK3	ENSG00000110422	-0.20137613354186676	[939,1016]	[714,647]	-6	dCas9-KRAB	negative selection	5484693
33257868	33257891	11	+	27661255	K562	viability	GAGAGCGCGGGCCTCTAGGAAGG	HIPK3	ENSG00000110422	0.06066182098494116	[421,669]	[563,354]	2	dCas9-KRAB	negative selection	5484694
33257874	33257897	11	+	27661255	K562	viability	GCGGGCCTCTAGGAAGGTAAGGG	HIPK3	ENSG00000110422	0.1449361907389194	[421,416]	[436,313]	5	dCas9-KRAB	negative selection	5484695
33257779	33257802	11	-	27661255	K562	viability	GAGCCAGGCGCTTCAGCAGGCGG	HIPK3	ENSG00000110422	-0.08718112029146108	[549,438]	[388,359]	-3	dCas9-KRAB	negative selection	5484696
33258593	33258616	11	-	27661255	K562	viability	GTGCGGCGAAGGGAAGCGGGCGG	HIPK3	ENSG00000110422	-0.26161236023839624	[906,730]	[583,516]	-6	dCas9-KRAB	negative selection	5484697
33286610	33286633	11	+	27260156	BXPC3	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.581610286784785	[174]	[89,139,88,177]	-8	hSpCas9	negative selection	5547484
33286780	33286803	11	-	27260156	BXPC3	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.1508400208908649	[1032]	[1134,1116,1281,1276]	3	hSpCas9	negative selection	5547485
33337078	33337101	11	+	27260156	BXPC3	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.5623633571396695	[230]	[370,366,312,371]	9	hSpCas9	negative selection	5547486
33328617	33328640	11	-	27260156	BXPC3	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.20935761447871348	[1862]	[1499,1412,1856,2040]	-5	hSpCas9	negative selection	5611745
33337107	33337130	11	+	27260156	BXPC3	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.0653421945967036	[591]	[555,535,538,757]	-1	hSpCas9	negative selection	5611746
33328514	33328537	11	-	27260156	BXPC3	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.07195524436018197	[283]	[226,312,274,321]	-2	hSpCas9	negative selection	5611747
33286610	33286633	11	+	27260156	A673	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.52747361757785	[174]	[111,162,162,139]	-8	hSpCas9	negative selection	5668735
33286780	33286803	11	-	27260156	A673	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.04656339980192259	[1032]	[1271,1319,1258,1267]	1	hSpCas9	negative selection	5668736
33337078	33337101	11	+	27260156	A673	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.4301915720036361	[230]	[373,303,390,429]	8	hSpCas9	negative selection	5668737
33328617	33328640	11	-	27260156	A673	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.2197872636777305	[1862]	[2381,1872,1536,1946]	-5	hSpCas9	negative selection	5732996
33337107	33337130	11	+	27260156	A673	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.058731608059153007	[591]	[728,661,611,734]	-1	hSpCas9	negative selection	5732997
33328514	33328537	11	-	27260156	A673	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.2001497344570552	[283]	[370,337,235,246]	-5	hSpCas9	negative selection	5732998
33286610	33286633	11	+	27260156	A375	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.5294836564565948	[174]	[137,156,112,157]	-6	hSpCas9	negative selection	5789986
33286780	33286803	11	-	27260156	A375	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.13501015319466791	[1032]	[1066,1779,1268,1248]	2	hSpCas9	negative selection	5789987
33337078	33337101	11	+	27260156	A375	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.4009379522831168	[230]	[286,383,464,297]	6	hSpCas9	negative selection	5789988
33328617	33328640	11	-	27260156	A375	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.010998049638301977	[1862]	[2072,2767,2051,1856]	0	hSpCas9	negative selection	5854247
33337107	33337130	11	+	27260156	A375	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.11422552633313968	[591]	[601,656,656,638]	-2	hSpCas9	negative selection	5854248
33328514	33328537	11	-	27260156	A375	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.19322901509398926	[283]	[417,454,307,348]	2	hSpCas9	negative selection	5854249
33286610	33286633	11	+	27260156	COLO741	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.1096814941837101	[174]	[178,275,166]	-2	hSpCas9	negative selection	5911237
33286780	33286803	11	-	27260156	COLO741	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.04926327799552377	[1032]	[1234,1617,1239]	1	hSpCas9	negative selection	5911238
33337078	33337101	11	+	27260156	COLO741	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.587422091465017	[230]	[418,472,435]	9	hSpCas9	negative selection	5911239
33328617	33328640	11	-	27260156	COLO741	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.09287045799730076	[1862]	[2915,2375,2362]	2	hSpCas9	negative selection	5975498
33337107	33337130	11	+	27260156	COLO741	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.13726405660744218	[591]	[1189,731,617]	3	hSpCas9	negative selection	5975499
33328514	33328537	11	-	27260156	COLO741	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.15276322361444972	[283]	[397,295,292]	-3	hSpCas9	negative selection	5975500
33286610	33286633	11	+	27260156	CAL120	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.4834856172622841	[174]	[223,126,126]	-6	hSpCas9	negative selection	6032488
33286780	33286803	11	-	27260156	CAL120	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.1707987282554969	[1032]	[1375,1191,896]	-3	hSpCas9	negative selection	6032489
33337078	33337101	11	+	27260156	CAL120	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.4872163652081388	[230]	[426,367,416]	7	hSpCas9	negative selection	6032490
33328617	33328640	11	-	27260156	CAL120	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.02218370883095533	[1862]	[2789,2180,1958]	0	hSpCas9	negative selection	6096749
33337107	33337130	11	+	27260156	CAL120	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.05742747510545554	[591]	[760,1015,525]	0	hSpCas9	negative selection	6096750
33328514	33328537	11	-	27260156	CAL120	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.14458551683918397	[283]	[290,250,410]	-2	hSpCas9	negative selection	6096751
33286610	33286633	11	+	27260156	CADOES1	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.03607885493978169	[174]	[67,218,171,176]	0	hSpCas9	negative selection	6153739
33286780	33286803	11	-	27260156	CADOES1	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.0652280148904345	[1032]	[1010,994,950,1065]	1	hSpCas9	negative selection	6153740
33337078	33337101	11	+	27260156	CADOES1	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.7085732694134979	[230]	[313,330,367,392]	9	hSpCas9	negative selection	6153741
33328617	33328640	11	-	27260156	CADOES1	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.08242222751861683	[1862]	[1454,1647,1790,1652]	-1	hSpCas9	negative selection	6218000
33337107	33337130	11	+	27260156	CADOES1	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.22078674933062648	[591]	[537,714,773,535]	4	hSpCas9	negative selection	6218001
33328514	33328537	11	-	27260156	CADOES1	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.04354826165750403	[283]	[227,248,389,219]	0	hSpCas9	negative selection	6218002
33286610	33286633	11	+	27260156	EWS502	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.07491462444817909	[174]	[149,205,190,156]	-1	hSpCas9	negative selection	6274990
33286780	33286803	11	-	27260156	EWS502	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.1200781721310531	[1032]	[824,1176,1230,792]	-2	hSpCas9	negative selection	6274991
33337078	33337101	11	+	27260156	EWS502	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.20240872108775232	[230]	[227,373,310,209]	3	hSpCas9	negative selection	6274992
33328617	33328640	11	-	27260156	EWS502	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.0039018040405023324	[1862]	[1715,1845,2105,2253]	0	hSpCas9	negative selection	6339251
33337107	33337130	11	+	27260156	EWS502	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.2207940779318026	[591]	[529,635,453,524]	-4	hSpCas9	negative selection	6339252
33328514	33328537	11	-	27260156	EWS502	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.06927709827460682	[283]	[257,276,330,283]	-1	hSpCas9	negative selection	6339253
33286610	33286633	11	+	27260156	EW8	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.6164061595882002	[174]	[100,51,100,114]	-8	hSpCas9	negative selection	6396241
33286780	33286803	11	-	27260156	EW8	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.06653095544043719	[1032]	[1024,944,770,797]	1	hSpCas9	negative selection	6396242
33337078	33337101	11	+	27260156	EW8	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.57729582907905	[230]	[378,243,203,312]	8	hSpCas9	negative selection	6396243
33328617	33328640	11	-	27260156	EW8	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.033770225446465796	[1862]	[2014,1503,1301,1449]	0	hSpCas9	negative selection	6460502
33337107	33337130	11	+	27260156	EW8	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.36803166203521354	[591]	[681,678,489,652]	6	hSpCas9	negative selection	6460503
33328514	33328537	11	-	27260156	EW8	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.2619790535495431	[283]	[261,222,133,165]	-5	hSpCas9	negative selection	6460504
33286610	33286633	11	+	27260156	CORL105	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.399429872594538	[174]	[115,97,288,138]	-6	hSpCas9	negative selection	6517492
33286780	33286803	11	-	27260156	CORL105	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.21298886032895958	[1032]	[1122,1498,1519,1470]	4	hSpCas9	negative selection	6517493
33337078	33337101	11	+	27260156	CORL105	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.38249121139469233	[230]	[382,343,431,264]	7	hSpCas9	negative selection	6517494
33328617	33328640	11	-	27260156	CORL105	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.14470174970271588	[1862]	[1856,1839,2139,2077]	-3	hSpCas9	negative selection	6581753
33337107	33337130	11	+	27260156	CORL105	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.016544900973053334	[591]	[792,738,601,656]	0	hSpCas9	negative selection	6581754
33328514	33328537	11	-	27260156	CORL105	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.08932826097656577	[283]	[223,325,433,438]	1	hSpCas9	negative selection	6581755
33286610	33286633	11	+	27260156	HS294T	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.6212637704534114	[174]	[34,29,38,78]	-7	hSpCas9	negative selection	6638743
33286780	33286803	11	-	27260156	HS294T	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.4728115087088942	[1032]	[487,513,567,672]	6	hSpCas9	negative selection	6638744
33337078	33337101	11	+	27260156	HS294T	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.515597814101134	[230]	[79,161,132,140]	7	hSpCas9	negative selection	6638745
33328617	33328640	11	-	27260156	HS294T	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.35583911252815903	[1862]	[853,762,728,1435]	5	hSpCas9	negative selection	6703004
33337107	33337130	11	+	27260156	HS294T	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.190206911994123	[591]	[241,200,167,183]	-3	hSpCas9	negative selection	6703005
33328514	33328537	11	-	27260156	HS294T	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.134817930485308	[283]	[64,122,120,91]	-2	hSpCas9	negative selection	6703006
33286610	33286633	11	+	27260156	HCC44	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.22822939588614433	[174]	[175,127,310,92]	-4	hSpCas9	negative selection	6759994
33286780	33286803	11	-	27260156	HCC44	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.09426349490714547	[1032]	[1070,832,1671,1509]	1	hSpCas9	negative selection	6759995
33337078	33337101	11	+	27260156	HCC44	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	-0.025006423164526614	[230]	[366,141,449,129]	0	hSpCas9	negative selection	6759996
33328617	33328640	11	-	27260156	HCC44	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.05711876797387938	[1862]	[1890,2013,2495,2392]	0	hSpCas9	negative selection	6824255
33337107	33337130	11	+	27260156	HCC44	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.06747821548691735	[591]	[710,391,821,696]	-1	hSpCas9	negative selection	6824256
33328514	33328537	11	-	27260156	HCC44	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.19148590557763845	[283]	[257,287,459,471]	3	hSpCas9	negative selection	6824257
33286610	33286633	11	+	27260156	G402	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.9685089657057062	[174]	[34,46,256,83]	-8	hSpCas9	negative selection	6881245
33286780	33286803	11	-	27260156	G402	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.2016766451899108	[1032]	[1334,1181,1611,1622]	2	hSpCas9	negative selection	6881246
33337078	33337101	11	+	27260156	G402	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	1.3673689956934894	[230]	[703,830,800,579]	9	hSpCas9	negative selection	6881247
33328617	33328640	11	-	27260156	G402	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.08253521242581408	[1862]	[2732,3060,1989,1942]	1	hSpCas9	negative selection	6945506
33337107	33337130	11	+	27260156	G402	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.10932702242801354	[591]	[1169,699,464,426]	-1	hSpCas9	negative selection	6945507
33328514	33328537	11	-	27260156	G402	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.5259364469722841	[283]	[834,541,402,275]	6	hSpCas9	negative selection	6945508
33286610	33286633	11	+	27260156	L33	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.3436976923057349	[174]	[186,41,124,62]	-7	hSpCas9	negative selection	7002496
33286780	33286803	11	-	27260156	L33	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.020529771033766187	[1032]	[918,470,617,1023]	0	hSpCas9	negative selection	7002497
33337078	33337101	11	+	27260156	L33	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.5608672563614232	[230]	[380,137,185,347]	9	hSpCas9	negative selection	7002498
33328617	33328640	11	-	27260156	L33	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.030761779335845674	[1862]	[1798,746,1204,1756]	0	hSpCas9	negative selection	7066757
33337107	33337130	11	+	27260156	L33	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.16976734509432634	[591]	[439,243,314,569]	-4	hSpCas9	negative selection	7066758
33328514	33328537	11	-	27260156	L33	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.07831121843688382	[283]	[298,128,100,422]	1	hSpCas9	negative selection	7066759
33286610	33286633	11	+	27260156	K562	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.2811299677319239	[174]	[176,45,202,88]	-3	hSpCas9	negative selection	7123747
33286780	33286803	11	-	27260156	K562	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.024799750282938238	[1032]	[775,1111,959,768]	0	hSpCas9	negative selection	7123748
33337078	33337101	11	+	27260156	K562	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.44946454921448387	[230]	[193,306,247,354]	6	hSpCas9	negative selection	7123749
33328617	33328640	11	-	27260156	K562	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.1562835012653816	[1862]	[1511,1617,1698,1147]	-2	hSpCas9	negative selection	7188008
33337107	33337130	11	+	27260156	K562	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.08051098078779878	[591]	[517,492,426,751]	1	hSpCas9	negative selection	7188009
33328514	33328537	11	-	27260156	K562	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.38298093325452787	[283]	[177,181,184,221]	-5	hSpCas9	negative selection	7188010
33286610	33286633	11	+	27260156	HT29	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.16272164683079615	[174]	[124,196,220,208]	-3	hSpCas9	negative selection	7244998
33286780	33286803	11	-	27260156	HT29	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.27726131709280555	[1032]	[1506,1662,1573,1362]	5	hSpCas9	negative selection	7244999
33337078	33337101	11	+	27260156	HT29	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.7542516900921423	[230]	[389,474,448,559]	9	hSpCas9	negative selection	7245000
33328617	33328640	11	-	27260156	HT29	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.12194617967621801	[1862]	[3018,2488,2257,2156]	2	hSpCas9	negative selection	7309259
33337107	33337130	11	+	27260156	HT29	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.11503357047892682	[591]	[686,825,827,768]	2	hSpCas9	negative selection	7309260
33328514	33328537	11	-	27260156	HT29	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.31196802845883476	[283]	[436,378,457,432]	6	hSpCas9	negative selection	7309261
33286610	33286633	11	+	27260156	MHHES1	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.06288791461162391	[174]	[254,212,135,217]	1	hSpCas9	negative selection	7366249
33286780	33286803	11	-	27260156	MHHES1	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.17768860558256505	[1032]	[1586,1492,1406,896]	3	hSpCas9	negative selection	7366250
33337078	33337101	11	+	27260156	MHHES1	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.40779890683950926	[230]	[399,441,311,255]	7	hSpCas9	negative selection	7366251
33328617	33328640	11	-	27260156	MHHES1	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.06753113311857595	[1862]	[2560,1937,2266,1401]	-1	hSpCas9	negative selection	7430510
33337107	33337130	11	+	27260156	MHHES1	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.17234551992088099	[591]	[475,941,373,582]	-3	hSpCas9	negative selection	7430511
33328514	33328537	11	-	27260156	MHHES1	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.04781502198556553	[283]	[456,323,300,194]	-1	hSpCas9	negative selection	7430512
33286610	33286633	11	+	27260156	MEWO	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.45583921467080524	[174]	[128,107,122]	-7	hSpCas9	negative selection	7487500
33286780	33286803	11	-	27260156	MEWO	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.12055615421732302	[1032]	[1217,1086,878]	2	hSpCas9	negative selection	7487501
33337078	33337101	11	+	27260156	MEWO	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.5664565773480719	[230]	[466,221,299]	9	hSpCas9	negative selection	7487502
33328617	33328640	11	-	27260156	MEWO	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.052647201281874834	[1862]	[1767,1692,1596]	-1	hSpCas9	negative selection	7551761
33337107	33337130	11	+	27260156	MEWO	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.1840981034782268	[591]	[367,536,533]	-4	hSpCas9	negative selection	7551762
33328514	33328537	11	-	27260156	MEWO	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.008002028557234198	[283]	[326,279,205]	0	hSpCas9	negative selection	7551763
33286610	33286633	11	+	27260156	LNCAPCLONEFGC	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-1.1775527489936748	[174]	[67,60,110,46]	-9	hSpCas9	negative selection	7608751
33286780	33286803	11	-	27260156	LNCAPCLONEFGC	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.3282921973994708	[1032]	[1148,1125,1131,1288]	5	hSpCas9	negative selection	7608752
33337078	33337101	11	+	27260156	LNCAPCLONEFGC	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.4922648965180283	[230]	[209,343,438,203]	7	hSpCas9	negative selection	7608753
33328617	33328640	11	-	27260156	LNCAPCLONEFGC	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.0007719803922940915	[1862]	[1926,1241,1966,1675]	0	hSpCas9	negative selection	7673012
33337107	33337130	11	+	27260156	LNCAPCLONEFGC	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.1376435545425692	[591]	[465,509,544,435]	-2	hSpCas9	negative selection	7673013
33328514	33328537	11	-	27260156	LNCAPCLONEFGC	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.2890313485569211	[283]	[388,242,385,252]	4	hSpCas9	negative selection	7673014
33286610	33286633	11	+	27260156	PANC0327	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-1.1264441554872742	[174]	[107,45,40,95]	-8	hSpCas9	negative selection	7730002
33286780	33286803	11	-	27260156	PANC0327	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.28432607280248656	[1032]	[949,1372,1071,1027]	4	hSpCas9	negative selection	7730003
33337078	33337101	11	+	27260156	PANC0327	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.5604349086741154	[230]	[529,231,219,255]	7	hSpCas9	negative selection	7730004
33328617	33328640	11	-	27260156	PANC0327	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.2975127659731178	[1862]	[2006,2399,1647,2029]	4	hSpCas9	negative selection	7794263
33337107	33337130	11	+	27260156	PANC0327	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.12678122630299382	[591]	[374,714,560,610]	1	hSpCas9	negative selection	7794264
33328514	33328537	11	-	27260156	PANC0327	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.002668589340960925	[283]	[281,219,355,155]	0	hSpCas9	negative selection	7794265
33286610	33286633	11	+	27260156	NCIH2009	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.5589696675065976	[174]	[80,155,243]	-6	hSpCas9	negative selection	7851253
33286780	33286803	11	-	27260156	NCIH2009	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.24262659202455028	[1032]	[1924,1808,1426]	3	hSpCas9	negative selection	7851254
33337078	33337101	11	+	27260156	NCIH2009	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.6474943282090322	[230]	[624,418,496]	8	hSpCas9	negative selection	7851255
33328617	33328640	11	-	27260156	NCIH2009	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.034870007493414734	[1862]	[2654,2882,2450]	0	hSpCas9	negative selection	7915514
33337107	33337130	11	+	27260156	NCIH2009	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.11561700134213876	[591]	[898,694,722]	-2	hSpCas9	negative selection	7915515
33328514	33328537	11	-	27260156	NCIH2009	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.07533541666045618	[283]	[593,376,317]	1	hSpCas9	negative selection	7915516
33286610	33286633	11	+	27260156	NCIH1373	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-1.4906588441085888	[174]	[67,91,12,27]	-9	hSpCas9	negative selection	7972504
33286780	33286803	11	-	27260156	NCIH1373	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.4519114502021446	[1032]	[2325,1020,1447,451]	4	hSpCas9	negative selection	7972505
33337078	33337101	11	+	27260156	NCIH1373	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	1.311830525240337	[230]	[1116,497,540,129]	9	hSpCas9	negative selection	7972506
33328617	33328640	11	-	27260156	NCIH1373	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.29502284602735407	[1862]	[1779,1600,1332,562]	-3	hSpCas9	negative selection	8036765
33337107	33337130	11	+	27260156	NCIH1373	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.35063255954562395	[591]	[577,618,606,66]	-4	hSpCas9	negative selection	8036766
33328514	33328537	11	-	27260156	NCIH1373	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.3167373895700659	[283]	[523,281,406,105]	3	hSpCas9	negative selection	8036767
33286610	33286633	11	+	27260156	PATU8902	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.14473219330743636	[174]	[188,267,234,179]	-1	hSpCas9	negative selection	8093755
33286780	33286803	11	-	27260156	PATU8902	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.2944518720545277	[1032]	[1473,1652,1455,2649]	3	hSpCas9	negative selection	8093756
33337078	33337101	11	+	27260156	PATU8902	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.19837894336157413	[230]	[360,286,436,370]	2	hSpCas9	negative selection	8093757
33328617	33328640	11	-	27260156	PATU8902	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.3584710713436352	[1862]	[1797,1689,1897,2822]	-4	hSpCas9	negative selection	8158016
33337107	33337130	11	+	27260156	PATU8902	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.054472642508177016	[591]	[422,1257,422,1511]	0	hSpCas9	negative selection	8158017
33328514	33328537	11	-	27260156	PATU8902	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.674144212890616	[283]	[425,233,136,214]	-6	hSpCas9	negative selection	8158018
33286610	33286633	11	+	27260156	PANC1	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.027347907344616118	[174]	[123,66,223,174]	0	hSpCas9	negative selection	8215006
33286780	33286803	11	-	27260156	PANC1	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.30632751664835633	[1032]	[1045,1216,1310,862]	5	hSpCas9	negative selection	8215007
33337078	33337101	11	+	27260156	PANC1	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.5588316822168212	[230]	[204,500,194,304]	8	hSpCas9	negative selection	8215008
33328617	33328640	11	-	27260156	PANC1	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.06348336988393277	[1862]	[1527,1946,1729,1537]	1	hSpCas9	negative selection	8279267
33337107	33337130	11	+	27260156	PANC1	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.15481901959916106	[591]	[505,669,652,465]	2	hSpCas9	negative selection	8279268
33328514	33328537	11	-	27260156	PANC1	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.3125950873593003	[283]	[209,268,250,85]	-5	hSpCas9	negative selection	8279269
33286610	33286633	11	+	27260156	PANC0813	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.10281177386482931	[174]	[146,137,117,348]	-2	hSpCas9	negative selection	8336257
33286780	33286803	11	-	27260156	PANC0813	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.13842798055800043	[1032]	[1237,1673,1189,1233]	2	hSpCas9	negative selection	8336258
33337078	33337101	11	+	27260156	PANC0813	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.8643684273710873	[230]	[436,413,718,405]	9	hSpCas9	negative selection	8336259
33328617	33328640	11	-	27260156	PANC0813	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.1466784272684365	[1862]	[2222,2013,2013,1691]	-2	hSpCas9	negative selection	8400518
33337107	33337130	11	+	27260156	PANC0813	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.46353861181435985	[591]	[420,560,475,547]	-6	hSpCas9	negative selection	8400519
33328514	33328537	11	-	27260156	PANC0813	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.2191044157195824	[283]	[321,375,154,294]	-4	hSpCas9	negative selection	8400520
33286610	33286633	11	+	27260156	RDES	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.6366636820162934	[174]	[139,155,88,119]	-8	hSpCas9	negative selection	8457508
33286780	33286803	11	-	27260156	RDES	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.16765988706242152	[1032]	[1083,1175,1489,1674]	2	hSpCas9	negative selection	8457509
33337078	33337101	11	+	27260156	RDES	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.4465953801961624	[230]	[316,321,377,446]	7	hSpCas9	negative selection	8457510
33328617	33328640	11	-	27260156	RDES	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.06267977431964256	[1862]	[1791,2161,2260,2868]	1	hSpCas9	negative selection	8521769
33337107	33337130	11	+	27260156	RDES	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.2124110241790027	[591]	[678,778,776,942]	3	hSpCas9	negative selection	8521770
33328514	33328537	11	-	27260156	RDES	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.10415638118438098	[283]	[277,254,293,403]	-2	hSpCas9	negative selection	8521771
33286610	33286633	11	+	27260156	PC3	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.045667835115027255	[174]	[147,77,360,202]	1	hSpCas9	negative selection	8578759
33286780	33286803	11	-	27260156	PC3	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.08390712205214834	[1032]	[780,1008,1734,1112]	2	hSpCas9	negative selection	8578760
33337078	33337101	11	+	27260156	PC3	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.7041501620665289	[230]	[466,225,431,293]	9	hSpCas9	negative selection	8578761
33328617	33328640	11	-	27260156	PC3	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.02959438024602723	[1862]	[969,1799,3608,1815]	0	hSpCas9	negative selection	8643020
33337107	33337130	11	+	27260156	PC3	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.03684479649608641	[591]	[398,755,652,651]	0	hSpCas9	negative selection	8643021
33328514	33328537	11	-	27260156	PC3	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.0670706214894703	[283]	[196,362,440,247]	1	hSpCas9	negative selection	8643022
33286610	33286633	11	+	27260156	PATU8988T	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.22452698352856815	[174]	[145,172,87,177]	-4	hSpCas9	negative selection	8700010
33286780	33286803	11	-	27260156	PATU8988T	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.19481933645926808	[1032]	[1126,1200,907,1359]	3	hSpCas9	negative selection	8700011
33337078	33337101	11	+	27260156	PATU8988T	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.40051423943731757	[230]	[202,335,402,233]	6	hSpCas9	negative selection	8700012
33328617	33328640	11	-	27260156	PATU8988T	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.037831905245001796	[1862]	[1590,1918,1662,1866]	0	hSpCas9	negative selection	8764271
33337107	33337130	11	+	27260156	PATU8988T	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.23758533205704685	[591]	[340,625,487,499]	-4	hSpCas9	negative selection	8764272
33328514	33328537	11	-	27260156	PATU8988T	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.056589227053225666	[283]	[227,317,324,271]	1	hSpCas9	negative selection	8764273
33286610	33286633	11	+	27260156	T47D	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.5674300794340548	[174]	[152,138,109,148]	-8	hSpCas9	negative selection	8821261
33286780	33286803	11	-	27260156	T47D	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.03800771586628238	[1032]	[1267,1086,1359,1237]	0	hSpCas9	negative selection	8821262
33337078	33337101	11	+	27260156	T47D	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.4587969926015206	[230]	[334,326,442,376]	8	hSpCas9	negative selection	8821263
33328617	33328640	11	-	27260156	T47D	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.08962559782704438	[1862]	[2331,2081,2520,2318]	2	hSpCas9	negative selection	8885522
33337107	33337130	11	+	27260156	T47D	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.014963576957783165	[591]	[662,663,617,790]	0	hSpCas9	negative selection	8885523
33328514	33328537	11	-	27260156	T47D	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.022017619055932136	[283]	[299,320,337,344]	0	hSpCas9	negative selection	8885524
33286610	33286633	11	+	27260156	SU8686	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.10763269365616424	[174]	[212,136,153,130]	-2	hSpCas9	negative selection	8942512
33286780	33286803	11	-	27260156	SU8686	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.2698591836032358	[1032]	[946,1145,1392,1542]	4	hSpCas9	negative selection	8942513
33337078	33337101	11	+	27260156	SU8686	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.39525064445091385	[230]	[173,257,383,429]	6	hSpCas9	negative selection	8942514
33328617	33328640	11	-	27260156	SU8686	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.04148765826719791	[1862]	[1926,1790,1660,2275]	0	hSpCas9	negative selection	9006773
33337107	33337130	11	+	27260156	SU8686	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.19133165524775841	[591]	[486,390,597,613]	-3	hSpCas9	negative selection	9006774
33328514	33328537	11	-	27260156	SU8686	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.22474280051755713	[283]	[226,360,345,398]	4	hSpCas9	negative selection	9006775
33286610	33286633	11	+	27260156	SKES1	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.5466633542789459	[174]	[145,142,107,89]	-8	hSpCas9	negative selection	9063763
33286780	33286803	11	-	27260156	SKES1	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.0674045143975468	[1032]	[1108,1263,1129,856]	1	hSpCas9	negative selection	9063764
33337078	33337101	11	+	27260156	SKES1	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.52821603909796	[230]	[413,245,410,262]	9	hSpCas9	negative selection	9063765
33328617	33328640	11	-	27260156	SKES1	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.03150318898877047	[1862]	[2144,2090,1827,1606]	0	hSpCas9	negative selection	9128024
33337107	33337130	11	+	27260156	SKES1	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.12342480801650668	[591]	[674,650,590,653]	2	hSpCas9	negative selection	9128025
33328514	33328537	11	-	27260156	SKES1	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.17042530579799153	[283]	[230,303,230,242]	-4	hSpCas9	negative selection	9128026
33286610	33286633	11	+	27260156	TOV112D	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	0.028142921839178214	[174]	[167,260,91,211]	0	hSpCas9	negative selection	9185014
33286780	33286803	11	-	27260156	TOV112D	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.14463993754535842	[1032]	[1157,1412,1164,910]	3	hSpCas9	negative selection	9185015
33337078	33337101	11	+	27260156	TOV112D	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	-0.518935301787433	[230]	[200,103,212,117]	-8	hSpCas9	negative selection	9185016
33328617	33328640	11	-	27260156	TOV112D	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.08227072686764969	[1862]	[1908,2308,2260,1508]	1	hSpCas9	negative selection	9249275
33337107	33337130	11	+	27260156	TOV112D	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.12583109330155712	[591]	[580,809,571,657]	2	hSpCas9	negative selection	9249276
33328514	33328537	11	-	27260156	TOV112D	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.19902281386826748	[283]	[347,192,207,236]	-4	hSpCas9	negative selection	9249277
33286610	33286633	11	+	27260156	TC71	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.3385821182051314	[174]	[168,104,171,145]	-7	hSpCas9	negative selection	9306265
33286780	33286803	11	-	27260156	TC71	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	-0.017014106205781587	[1032]	[1006,1239,1108,1017]	0	hSpCas9	negative selection	9306266
33337078	33337101	11	+	27260156	TC71	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.3283623942685596	[230]	[273,259,352,358]	7	hSpCas9	negative selection	9306267
33328617	33328640	11	-	27260156	TC71	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	0.05871896770014806	[1862]	[2025,2187,2024,2083]	1	hSpCas9	negative selection	9370526
33337107	33337130	11	+	27260156	TC71	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	-0.01987066885293054	[591]	[578,663,558,709]	0	hSpCas9	negative selection	9370527
33328514	33328537	11	-	27260156	TC71	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	-0.1424848247751599	[283]	[234,348,285,230]	-4	hSpCas9	negative selection	9370528
33286610	33286633	11	+	27260156	TC32	viability	ATACCATTTAATAGACCTCGAGG	HIPK3	ENSG00000110422	-0.3554754494269987	[174]	[77,167,173,81]	-6	hSpCas9	negative selection	9427516
33286780	33286803	11	-	27260156	TC32	viability	TGCGCTTCAATCCACATCGCTGG	HIPK3	ENSG00000110422	0.07428896929319495	[1032]	[969,716,1460,1081]	1	hSpCas9	negative selection	9427517
33337078	33337101	11	+	27260156	TC32	viability	CGATACATTTCTCAGACTCAAGG	HIPK3	ENSG00000110422	0.6127072398722107	[230]	[304,280,398,357]	8	hSpCas9	negative selection	9427518
33328617	33328640	11	-	27260156	TC32	viability	TGTTACCTGATCATACTCCAAGG	HIPK3	ENSG00000110422	-0.015381220786724326	[1862]	[1693,1267,1973,2133]	0	hSpCas9	negative selection	9491777
33337107	33337130	11	+	27260156	TC32	viability	AGGAGAACAGTTGTTAAATGTGG	HIPK3	ENSG00000110422	0.18375831575203527	[591]	[558,545,801,653]	3	hSpCas9	negative selection	9491778
33328514	33328537	11	-	27260156	TC32	viability	GGCAACCCCAATATAATCTCTGG	HIPK3	ENSG00000110422	0.10957714289348341	[283]	[166,303,417,275]	2	hSpCas9	negative selection	9491779
33287316	33287339	11	-	27869803	HPAFII	viability after 27 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.9727506989128774	[342]	[414,302,NaN]	7	hSpCas9	negative selection	9541266
33328592	33328615	11	+	27869803	HPAFII	viability after 27 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.040806826556441245	[313]	[105,222,NaN]	0	hSpCas9	negative selection	9541267
33347379	33347402	11	+	27869803	HPAFII	viability after 27 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.21053842235472253	[468]	[253,178,NaN]	-1	hSpCas9	negative selection	9541268
33347612	33347635	11	+	27869803	HPAFII	viability after 27 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-0.9243209066351624	[147]	[22,55,NaN]	-6	hSpCas9	negative selection	9541269
33348179	33348202	11	+	27869803	HPAFII	viability after 27 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	1.0461585758177956	[103]	[167,66,NaN]	8	hSpCas9	negative selection	9541270
33348627	33348650	11	+	27869803	HPAFII	viability after 27 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	0.6983215338802624	[283]	[238,244,NaN]	5	hSpCas9	negative selection	9541271
33287316	33287339	11	-	27869803	HPAFII	viability after 15 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	1.1045014361391225	[342]	[968,682,NaN]	9	hSpCas9	negative selection	9623715
33328592	33328615	11	+	27869803	HPAFII	viability after 15 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.12240186040997653	[313]	[502,282,NaN]	1	hSpCas9	negative selection	9623716
33347379	33347402	11	+	27869803	HPAFII	viability after 15 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.2542609950828483	[468]	[622,297,NaN]	-3	hSpCas9	negative selection	9623717
33347612	33347635	11	+	27869803	HPAFII	viability after 15 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-1.0878071615941391	[147]	[80,70,NaN]	-8	hSpCas9	negative selection	9623718
33348179	33348202	11	+	27869803	HPAFII	viability after 15 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.9650675897311054	[103]	[351,134,NaN]	9	hSpCas9	negative selection	9623719
33348627	33348650	11	+	27869803	HPAFII	viability after 15 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	0.6624798543694963	[283]	[389,540,NaN]	7	hSpCas9	negative selection	9623720
33287316	33287339	11	-	27869803	ASPC1	viability after 36 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.4214138396293383	[1106]	[397,723,431]	4	hSpCas9	negative selection	9706164
33328592	33328615	11	+	27869803	ASPC1	viability after 36 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	-0.06675330561323564	[751]	[528,214,80]	0	hSpCas9	negative selection	9706165
33347379	33347402	11	+	27869803	ASPC1	viability after 36 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.0477640556519473	[1233]	[188,679,433]	0	hSpCas9	negative selection	9706166
33347612	33347635	11	+	27869803	ASPC1	viability after 36 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-0.8270555678322149	[450]	[109,41,109]	-7	hSpCas9	negative selection	9706167
33348179	33348202	11	+	27869803	ASPC1	viability after 36 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	-0.08227076158240587	[361]	[121,193,56]	-1	hSpCas9	negative selection	9706168
33348627	33348650	11	+	27869803	ASPC1	viability after 36 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-1.0057045847703667	[655]	[159,139,59]	-7	hSpCas9	negative selection	9706169
33287316	33287339	11	-	27869803	PATU8988S	viability after 35 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.4560273906978306	[915]	[535,475,NaN]	5	hSpCas9	negative selection	9788613
33328592	33328615	11	+	27869803	PATU8988S	viability after 35 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.6719765836654956	[637]	[362,455,NaN]	7	hSpCas9	negative selection	9788614
33347379	33347402	11	+	27869803	PATU8988S	viability after 35 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.2941234659566452	[1011]	[391,607,NaN]	3	hSpCas9	negative selection	9788615
33347612	33347635	11	+	27869803	PATU8988S	viability after 35 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-0.27025970117605314	[294]	[104,91,NaN]	-3	hSpCas9	negative selection	9788616
33348179	33348202	11	+	27869803	PATU8988S	viability after 35 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.630596424735371	[202]	[160,91,NaN]	7	hSpCas9	negative selection	9788617
33348627	33348650	11	+	27869803	PATU8988S	viability after 35 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.0985092197690827	[464]	[138,210,NaN]	-1	hSpCas9	negative selection	9788618
33287316	33287339	11	-	27869803	PATU8988S	viability after 31 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	0.34408765805870833	[915]	[405,536,NaN]	4	hSpCas9	negative selection	9871062
33328592	33328615	11	+	27869803	PATU8988S	viability after 31 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.34220485602198863	[637]	[219,452,NaN]	4	hSpCas9	negative selection	9871063
33347379	33347402	11	+	27869803	PATU8988S	viability after 31 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	0.13302574419142732	[1011]	[372,530,NaN]	1	hSpCas9	negative selection	9871064
33347612	33347635	11	+	27869803	PATU8988S	viability after 31 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	0.157490035121296	[294]	[117,147,NaN]	2	hSpCas9	negative selection	9871065
33348179	33348202	11	+	27869803	PATU8988S	viability after 31 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	0.8717998573580809	[202]	[170,118,NaN]	8	hSpCas9	negative selection	9871066
33348627	33348650	11	+	27869803	PATU8988S	viability after 31 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	-0.22171618445601007	[464]	[169,144,NaN]	-3	hSpCas9	negative selection	9871067
33287316	33287339	11	-	27869803	HPAFII	viability after 35 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	1.0791472029862008	[342]	[459,261,NaN]	7	hSpCas9	negative selection	9953511
33328592	33328615	11	+	27869803	HPAFII	viability after 35 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.7448709840253644	[313]	[105,446,NaN]	5	hSpCas9	negative selection	9953512
33347379	33347402	11	+	27869803	HPAFII	viability after 35 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.4440926142130973	[468]	[158,191,NaN]	-3	hSpCas9	negative selection	9953513
33347612	33347635	11	+	27869803	HPAFII	viability after 35 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-1.0024289418149182	[147]	[11,65,NaN]	-5	hSpCas9	negative selection	9953514
33348179	33348202	11	+	27869803	HPAFII	viability after 35 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	1.1369728416734795	[103]	[159,65,NaN]	7	hSpCas9	negative selection	9953515
33348627	33348650	11	+	27869803	HPAFII	viability after 35 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	0.38139933454419994	[283]	[159,217,NaN]	2	hSpCas9	negative selection	9953516
33287316	33287339	11	-	27869803	HPAFII	viability after 31 days	AGTGGCCACTTGTTGAAGAATGG	HIPK3	ENSG00000110422	1.3332323574722436	[342]	[507,459,NaN]	8	hSpCas9	negative selection	10035960
33328592	33328615	11	+	27869803	HPAFII	viability after 31 days	CTTGGATGGCCGCTCTACCCAGG	HIPK3	ENSG00000110422	0.3561909845862634	[313]	[81,381,NaN]	2	hSpCas9	negative selection	10035961
33347379	33347402	11	+	27869803	HPAFII	viability after 31 days	CAGCCACTACAGATCCGACCAGG	HIPK3	ENSG00000110422	-0.9220217517563565	[468]	[136,140,NaN]	-5	hSpCas9	negative selection	10035962
33347612	33347635	11	+	27869803	HPAFII	viability after 31 days	TGCTTTGCTGCAAGCAGACGTGG	HIPK3	ENSG00000110422	-0.41310355805473653	[147]	[14,113,NaN]	-3	hSpCas9	negative selection	10035963
33348179	33348202	11	+	27869803	HPAFII	viability after 31 days	AAACTAATGGAATGGGAGCCAGG	HIPK3	ENSG00000110422	1.569345591438414	[103]	[244,94,NaN]	9	hSpCas9	negative selection	10035964
33348627	33348650	11	+	27869803	HPAFII	viability after 31 days	CAATCAGAACTCAGAAGGAGAGG	HIPK3	ENSG00000110422	0.7843614989312434	[283]	[218,334,NaN]	6	hSpCas9	negative selection	10035965
33347683	33347706	11	-	28162770	P31FUJ	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.30379727474537854	[90]	[131]	3	hSpCas9	negative selection	10168938
33349245	33349268	11	-	28162770	P31FUJ	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	0.5467621018526568	[306]	[526]	6	hSpCas9	negative selection	10168939
33348745	33348768	11	-	28162770	P31FUJ	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	0.5849944643648723	[58]	[103]	6	hSpCas9	negative selection	10168940
33286708	33286731	11	+	28162770	P31FUJ	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.7000835997270843	[87]	[167]	7	hSpCas9	negative selection	10168941
33286795	33286818	11	+	28162770	P31FUJ	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-0.6434345245732214	[108]	[81]	-5	hSpCas9	negative selection	10168942
33286901	33286924	11	+	28162770	P31FUJ	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	-0.6333401339981077	[65]	[49]	-5	hSpCas9	negative selection	10168943
33328509	33328532	11	+	28162770	P31FUJ	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.24629166119995483	[423]	[590]	2	hSpCas9	negative selection	10168944
33347352	33347375	11	-	28162770	P31FUJ	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.087354625620791	[325]	[406]	0	hSpCas9	negative selection	10168945
33347892	33347915	11	-	28162770	P31FUJ	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.5170255406888771	[200]	[337]	6	hSpCas9	negative selection	10168946
33348692	33348715	11	+	28162770	P31FUJ	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.34990078912465256	[212]	[318]	4	hSpCas9	negative selection	10168947
33347683	33347706	11	-	28162770	TF1	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	NaN	[NaN]	[42]	1	hSpCas9	negative selection	10338304
33349245	33349268	11	-	28162770	TF1	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	NaN	[NaN]	[368]	1	hSpCas9	negative selection	10338305
33348745	33348768	11	-	28162770	TF1	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10338306
33286708	33286731	11	+	28162770	TF1	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10338307
33286795	33286818	11	+	28162770	TF1	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10338308
33286901	33286924	11	+	28162770	TF1	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	NaN	[NaN]	[128]	1	hSpCas9	negative selection	10338309
33328509	33328532	11	+	28162770	TF1	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	NaN	[NaN]	[558]	1	hSpCas9	negative selection	10338310
33347352	33347375	11	-	28162770	TF1	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	NaN	[NaN]	[131]	1	hSpCas9	negative selection	10338311
33347892	33347915	11	-	28162770	TF1	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10338312
33348692	33348715	11	+	28162770	TF1	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10338313
33347683	33347706	11	-	28162770	SKM1	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	-0.2995806633695621	[54]	[78]	-3	hSpCas9	negative selection	10507670
33349245	33349268	11	-	28162770	SKM1	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	1.8337821398888476	[52]	[333]	9	hSpCas9	negative selection	10507671
33348745	33348768	11	-	28162770	SKM1	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	0.1779983019779947	[20]	[41]	1	hSpCas9	negative selection	10507672
33286708	33286731	11	+	28162770	SKM1	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.24671105206200888	[40]	[85]	2	hSpCas9	negative selection	10507673
33286795	33286818	11	+	28162770	SKM1	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-0.4831997845702467	[33]	[42]	-4	hSpCas9	negative selection	10507674
33286901	33286924	11	+	28162770	SKM1	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	0.6474835852792148	[25]	[71]	6	hSpCas9	negative selection	10507675
33328509	33328532	11	+	28162770	SKM1	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.09696172988708818	[118]	[224]	0	hSpCas9	negative selection	10507676
33347352	33347375	11	-	28162770	SKM1	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.7554271300137433	[63]	[190]	7	hSpCas9	negative selection	10507677
33347892	33347915	11	-	28162770	SKM1	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.7629608026991508	[31]	[95]	7	hSpCas9	negative selection	10507678
33348692	33348715	11	+	28162770	SKM1	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	1.028854862672185	[27]	[100]	8	hSpCas9	negative selection	10507679
33347683	33347706	11	-	28162770	SKM1	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	-0.2995806633695621	[54]	[78]	-3	hSpCas9	negative selection	10677036
33349245	33349268	11	-	28162770	SKM1	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	1.8337821398888476	[52]	[333]	9	hSpCas9	negative selection	10677037
33348745	33348768	11	-	28162770	SKM1	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	0.1779983019779947	[20]	[41]	1	hSpCas9	negative selection	10677038
33286708	33286731	11	+	28162770	SKM1	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.24671105206200888	[40]	[85]	2	hSpCas9	negative selection	10677039
33286795	33286818	11	+	28162770	SKM1	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-0.4831997845702467	[33]	[42]	-4	hSpCas9	negative selection	10677040
33286901	33286924	11	+	28162770	SKM1	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	0.6474835852792148	[25]	[71]	6	hSpCas9	negative selection	10677041
33328509	33328532	11	+	28162770	SKM1	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.09696172988708818	[118]	[224]	0	hSpCas9	negative selection	10677042
33347352	33347375	11	-	28162770	SKM1	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.7554271300137433	[63]	[190]	7	hSpCas9	negative selection	10677043
33347892	33347915	11	-	28162770	SKM1	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.7629608026991508	[31]	[95]	7	hSpCas9	negative selection	10677044
33348692	33348715	11	+	28162770	SKM1	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	1.028854862672185	[27]	[100]	8	hSpCas9	negative selection	10677045
33347683	33347706	11	-	28162770	PL21	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.17265887806721308	[158]	[77]	1	hSpCas9	negative selection	10846402
33349245	33349268	11	-	28162770	PL21	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.24499991657894268	[225]	[82]	-2	hSpCas9	negative selection	10846403
33348745	33348768	11	-	28162770	PL21	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	0.6298238897325653	[97]	[65]	5	hSpCas9	negative selection	10846404
33286708	33286731	11	+	28162770	PL21	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	-2.1859188178177575	[114]	[10]	-8	hSpCas9	negative selection	10846405
33286795	33286818	11	+	28162770	PL21	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-0.3482970102067223	[116]	[39]	-3	hSpCas9	negative selection	10846406
33286901	33286924	11	+	28162770	PL21	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	1.5581871351833343	[70]	[90]	9	hSpCas9	negative selection	10846407
33328509	33328532	11	+	28162770	PL21	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	-0.25641715422779054	[375]	[136]	-2	hSpCas9	negative selection	10846408
33347352	33347375	11	-	28162770	PL21	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.5438720796950309	[196]	[124]	5	hSpCas9	negative selection	10846409
33347892	33347915	11	-	28162770	PL21	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.6822913096267008	[188]	[131]	6	hSpCas9	negative selection	10846410
33348692	33348715	11	+	28162770	PL21	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.5772092635691435	[153]	[99]	5	hSpCas9	negative selection	10846411
33347683	33347706	11	-	28162770	P31FUJ	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.30379727474537854	[90]	[131]	3	hSpCas9	negative selection	11015768
33349245	33349268	11	-	28162770	P31FUJ	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	0.5467621018526568	[306]	[526]	6	hSpCas9	negative selection	11015769
33348745	33348768	11	-	28162770	P31FUJ	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	0.5849944643648723	[58]	[103]	6	hSpCas9	negative selection	11015770
33286708	33286731	11	+	28162770	P31FUJ	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.7000835997270843	[87]	[167]	7	hSpCas9	negative selection	11015771
33286795	33286818	11	+	28162770	P31FUJ	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-0.6434345245732214	[108]	[81]	-5	hSpCas9	negative selection	11015772
33286901	33286924	11	+	28162770	P31FUJ	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	-0.6333401339981077	[65]	[49]	-5	hSpCas9	negative selection	11015773
33328509	33328532	11	+	28162770	P31FUJ	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.24629166119995483	[423]	[590]	2	hSpCas9	negative selection	11015774
33347352	33347375	11	-	28162770	P31FUJ	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.087354625620791	[325]	[406]	0	hSpCas9	negative selection	11015775
33347892	33347915	11	-	28162770	P31FUJ	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.5170255406888771	[200]	[337]	6	hSpCas9	negative selection	11015776
33348692	33348715	11	+	28162770	P31FUJ	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.34990078912465256	[212]	[318]	4	hSpCas9	negative selection	11015777
33347683	33347706	11	-	28162770	OCIAML5	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.8737584656970087	[64]	[214]	7	hSpCas9	negative selection	11185134
33349245	33349268	11	-	28162770	OCIAML5	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.4171295141474483	[215]	[291]	-3	hSpCas9	negative selection	11185135
33348745	33348768	11	-	28162770	OCIAML5	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-0.35326071389255526	[91]	[129]	-3	hSpCas9	negative selection	11185136
33286708	33286731	11	+	28162770	OCIAML5	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	-0.09915943282876927	[53]	[90]	0	hSpCas9	negative selection	11185137
33286795	33286818	11	+	28162770	OCIAML5	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.052776196095662975	[46]	[87]	0	hSpCas9	negative selection	11185138
33286901	33286924	11	+	28162770	OCIAML5	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	-0.7525308973130824	[41]	[44]	-5	hSpCas9	negative selection	11185139
33328509	33328532	11	+	28162770	OCIAML5	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.19646332306366165	[379]	[785]	1	hSpCas9	negative selection	11185140
33347352	33347375	11	-	28162770	OCIAML5	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	-0.43552076507987614	[238]	[318]	-3	hSpCas9	negative selection	11185141
33347892	33347915	11	-	28162770	OCIAML5	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	1.179297600045338	[90]	[371]	8	hSpCas9	negative selection	11185142
33348692	33348715	11	+	28162770	OCIAML5	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	-0.09307467036779205	[181]	[307]	0	hSpCas9	negative selection	11185143
33347683	33347706	11	-	28162770	EOL1	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.3712308974658436	[247]	[168]	3	hSpCas9	negative selection	11354500
33349245	33349268	11	-	28162770	EOL1	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	0.15862199795461768	[368]	[216]	1	hSpCas9	negative selection	11354501
33348745	33348768	11	-	28162770	EOL1	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-0.5737030959572909	[112]	[39]	-4	hSpCas9	negative selection	11354502
33286708	33286731	11	+	28162770	EOL1	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	-0.47400160491974036	[231]	[87]	-4	hSpCas9	negative selection	11354503
33286795	33286818	11	+	28162770	EOL1	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.976743982695963	[189]	[196]	8	hSpCas9	negative selection	11354504
33286901	33286924	11	+	28162770	EOL1	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	0.4825432246914213	[143]	[105]	4	hSpCas9	negative selection	11354505
33328509	33328532	11	+	28162770	EOL1	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.06176045870202895	[450]	[247]	0	hSpCas9	negative selection	11354506
33347352	33347375	11	-	28162770	EOL1	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.9703514611836592	[278]	[287]	8	hSpCas9	negative selection	11354507
33347892	33347915	11	-	28162770	EOL1	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.528287479322319	[228]	[173]	5	hSpCas9	negative selection	11354508
33348692	33348715	11	+	28162770	EOL1	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.9314671855103251	[207]	[208]	7	hSpCas9	negative selection	11354509
33347683	33347706	11	-	28162770	MOLM13	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.9990137306381848	[181]	[262]	7	hSpCas9	negative selection	11523866
33349245	33349268	11	-	28162770	MOLM13	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-1.474007663891853	[364]	[94]	-6	hSpCas9	negative selection	11523867
33348745	33348768	11	-	28162770	MOLM13	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-1.4989437545202218	[85]	[21]	-6	hSpCas9	negative selection	11523868
33286708	33286731	11	+	28162770	MOLM13	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	1.5020664968626667	[145]	[298]	9	hSpCas9	negative selection	11523869
33286795	33286818	11	+	28162770	MOLM13	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.6671981897679853	[107]	[123]	5	hSpCas9	negative selection	11523870
33286901	33286924	11	+	28162770	MOLM13	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	0.33156791033179867	[121]	[110]	2	hSpCas9	negative selection	11523871
33328509	33328532	11	+	28162770	MOLM13	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	-0.4787473928566962	[689]	[357]	-3	hSpCas9	negative selection	11523872
33347352	33347375	11	-	28162770	MOLM13	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	1.1484295422479662	[291]	[467]	8	hSpCas9	negative selection	11523873
33347892	33347915	11	-	28162770	MOLM13	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.024054617958300065	[252]	[185]	0	hSpCas9	negative selection	11523874
33348692	33348715	11	+	28162770	MOLM13	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	-1.0952136852128382	[392]	[132]	-5	hSpCas9	negative selection	11523875
33347683	33347706	11	-	28162770	HEL	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.8695096938473792	[140]	[164]	7	hSpCas9	negative selection	11693232
33349245	33349268	11	-	28162770	HEL	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.09956020646888977	[270]	[161]	0	hSpCas9	negative selection	11693233
33348745	33348768	11	-	28162770	HEL	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	1.0668785383864532	[78]	[105]	8	hSpCas9	negative selection	11693234
33286708	33286731	11	+	28162770	HEL	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.29985111847734863	[155]	[122]	2	hSpCas9	negative selection	11693235
33286795	33286818	11	+	28162770	HEL	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.5475815989600168	[140]	[131]	4	hSpCas9	negative selection	11693236
33286901	33286924	11	+	28162770	HEL	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	1.1752339128273777	[111]	[161]	8	hSpCas9	negative selection	11693237
33328509	33328532	11	+	28162770	HEL	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	-0.5624514992611522	[527]	[228]	-4	hSpCas9	negative selection	11693238
33347352	33347375	11	-	28162770	HEL	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.45009375405796115	[279]	[244]	4	hSpCas9	negative selection	11693239
33347892	33347915	11	-	28162770	HEL	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.7874739249813677	[198]	[219]	6	hSpCas9	negative selection	11693240
33348692	33348715	11	+	28162770	HEL	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	-0.44153008489724693	[281]	[132]	-3	hSpCas9	negative selection	11693241
33347683	33347706	11	-	28162770	MV411	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.1701318246153265	[114]	[108]	1	hSpCas9	negative selection	11862598
33349245	33349268	11	-	28162770	MV411	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	-0.37480596601784044	[293]	[190]	-3	hSpCas9	negative selection	11862599
33348745	33348768	11	-	28162770	MV411	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-0.30649805431775623	[68]	[46]	-2	hSpCas9	negative selection	11862600
33286708	33286731	11	+	28162770	MV411	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	-0.4062377000223951	[128]	[81]	-3	hSpCas9	negative selection	11862601
33286795	33286818	11	+	28162770	MV411	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.1853765826505237	[94]	[90]	1	hSpCas9	negative selection	11862602
33286901	33286924	11	+	28162770	MV411	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	-0.5128920364489413	[82]	[48]	-4	hSpCas9	negative selection	11862603
33328509	33328532	11	+	28162770	MV411	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	-0.36006751858946917	[386]	[253]	-3	hSpCas9	negative selection	11862604
33347352	33347375	11	-	28162770	MV411	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.14052234686626341	[265]	[246]	1	hSpCas9	negative selection	11862605
33347892	33347915	11	-	28162770	MV411	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.4310374891221642	[139]	[158]	4	hSpCas9	negative selection	11862606
33348692	33348715	11	+	28162770	MV411	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.5166241835981643	[155]	[187]	4	hSpCas9	negative selection	11862607
33347683	33347706	11	-	28162770	MONOMAC1	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.6960479490239344	[55]	[103]	6	hSpCas9	negative selection	12031964
33349245	33349268	11	-	28162770	MONOMAC1	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	0.26154836789204694	[154]	[212]	2	hSpCas9	negative selection	12031965
33348745	33348768	11	-	28162770	MONOMAC1	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-0.3023898472057823	[70]	[65]	-3	hSpCas9	negative selection	12031966
33286708	33286731	11	+	28162770	MONOMAC1	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	-1.1970368470595536	[53]	[26]	-7	hSpCas9	negative selection	12031967
33286795	33286818	11	+	28162770	MONOMAC1	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.24224819846596746	[58]	[79]	2	hSpCas9	negative selection	12031968
33286901	33286924	11	+	28162770	MONOMAC1	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	-2.4700553414659696	[57]	[11]	-9	hSpCas9	negative selection	12031969
33328509	33328532	11	+	28162770	MONOMAC1	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	-1.0276824191033769	[280]	[157]	-7	hSpCas9	negative selection	12031970
33347352	33347375	11	-	28162770	MONOMAC1	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.07980335829927046	[103]	[125]	0	hSpCas9	negative selection	12031971
33347892	33347915	11	-	28162770	MONOMAC1	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.214940852470232	[117]	[156]	2	hSpCas9	negative selection	12031972
33348692	33348715	11	+	28162770	MONOMAC1	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	-0.44784495056008816	[93]	[78]	-4	hSpCas9	negative selection	12031973
33347683	33347706	11	-	28162770	OCIAML2	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	0.9530517684459341	[25]	[278]	8	hSpCas9	negative selection	12201330
33349245	33349268	11	-	28162770	OCIAML2	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	0.296924088757468	[41]	[285]	3	hSpCas9	negative selection	12201331
33348745	33348768	11	-	28162770	OCIAML2	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	0.9582134735617129	[12]	[139]	8	hSpCas9	negative selection	12201332
33286708	33286731	11	+	28162770	OCIAML2	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	0.7898977249810578	[23]	[229]	7	hSpCas9	negative selection	12201333
33286795	33286818	11	+	28162770	OCIAML2	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	0.18472200337039302	[19]	[125]	1	hSpCas9	negative selection	12201334
33286901	33286924	11	+	28162770	OCIAML2	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	0.3219280948873622	[13]	[96]	3	hSpCas9	negative selection	12201335
33328509	33328532	11	+	28162770	OCIAML2	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.14483476387633898	[77]	[477]	1	hSpCas9	negative selection	12201336
33347352	33347375	11	-	28162770	OCIAML2	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.4038392926739799	[38]	[285]	4	hSpCas9	negative selection	12201337
33347892	33347915	11	-	28162770	OCIAML2	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.48046057427689237	[29]	[231]	4	hSpCas9	negative selection	12201338
33348692	33348715	11	+	28162770	OCIAML2	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.6586531917028051	[27]	[244]	6	hSpCas9	negative selection	12201339
33347683	33347706	11	-	28162770	OCIAML3	viability	GTAGTAGTAGCAGGAGCCAGGGG	HIPK3	ENSG00000110422	-0.291444870303732	[44]	[110]	-2	hSpCas9	negative selection	12370696
33349245	33349268	11	-	28162770	OCIAML3	viability	GGATGGGCTGGACTGCCCTGAGG	HIPK3	ENSG00000110422	0.0649554418407699	[56]	[179]	0	hSpCas9	negative selection	12370697
33348745	33348768	11	-	28162770	OCIAML3	viability	ATAGTGATGACACTCACTGCAGG	HIPK3	ENSG00000110422	-0.3875567628567369	[12]	[29]	-3	hSpCas9	negative selection	12370698
33286708	33286731	11	+	28162770	OCIAML3	viability	GGCACAGCAAGCTCACGTGCAGG	HIPK3	ENSG00000110422	-0.8467737107041299	[27]	[46]	-6	hSpCas9	negative selection	12370699
33286795	33286818	11	+	28162770	OCIAML3	viability	GAAGCGCAAGAGTGAGGAGTTGG	HIPK3	ENSG00000110422	-1.2595886012536042	[22]	[28]	-7	hSpCas9	negative selection	12370700
33286901	33286924	11	+	28162770	OCIAML3	viability	ACAGTTGTGACAGCTACCACAGG	HIPK3	ENSG00000110422	1.6987741089036827	[14]	[146]	9	hSpCas9	negative selection	12370701
33328509	33328532	11	+	28162770	OCIAML3	viability	GAGCTCCAGAGATTATATTGGGG	HIPK3	ENSG00000110422	0.2372853363901959	[110]	[394]	2	hSpCas9	negative selection	12370702
33347352	33347375	11	-	28162770	OCIAML3	viability	GCTGGGGCCTGAGTTACAAGTGG	HIPK3	ENSG00000110422	0.9137869998745332	[63]	[363]	7	hSpCas9	negative selection	12370703
33347892	33347915	11	-	28162770	OCIAML3	viability	TGATTGGTCAGAAGAGGCTGCGG	HIPK3	ENSG00000110422	0.6443970990009157	[31]	[150]	6	hSpCas9	negative selection	12370704
33348692	33348715	11	+	28162770	OCIAML3	viability	CATCAGTTTCAGACAAACAGCGG	HIPK3	ENSG00000110422	0.39861282931023934	[48]	[194]	4	hSpCas9	negative selection	12370705