| 48543339 | 48543362 | 17 | + | 26627737 | DLD1 | viability | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.8709113244273597 | [294] | [179,136,184] | 8 | hSpCas9 | negative selection | 798468 | 48543339 | 48543362 | 17 | + | 26627737 | GBM cells | viability after 5 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.5834120491577561 | [195] | [151,162] | 8 | hSpCas9 | negative selection | 880783 | 48543339 | 48543362 | 17 | + | 26627737 | GBM cells | viability after 13 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.44209870878302826 | [195] | [208,91] | 5 | hSpCas9 | negative selection | 963098 | 48543339 | 48543362 | 17 | + | 26627737 | GBM cells | viability after 21 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.7663432093599061 | [195] | [189,172] | 7 | hSpCas9 | negative selection | 1045413 | 48543339 | 48543362 | 17 | + | 26627737 | RPE1 | viability after 9 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 1.576555780798288 | [296] | [282,269] | 8 | hSpCas9 | negative selection | 1127728 | 48543339 | 48543362 | 17 | + | 26627737 | RPE1 | viability after 12 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 1.4147591747789183 | [296] | [254,167] | 7 | hSpCas9 | negative selection | 1210043 | 48543339 | 48543362 | 17 | + | 26627737 | RPE1 | viability after 15 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 1.4350275202064937 | [296] | [245,208] | 7 | hSpCas9 | negative selection | 1292358 | 48543339 | 48543362 | 17 | + | 26627737 | RPE1 | viability after 18 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 1.605329678949549 | [296] | [312,169] | 8 | hSpCas9 | negative selection | 1374673 | 48543339 | 48543362 | 17 | + | 26627737 | HeLa | viability after 8 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.128315259615986 | [416] | [104,145,314] | 1 | hSpCas9 | negative selection | 1456988 | 48543339 | 48543362 | 17 | + | 26627737 | HeLa | viability after 12 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | -0.17067338437855234 | [416] | [48,202,198] | -1 | hSpCas9 | negative selection | 1539303 | 48543339 | 48543362 | 17 | + | 26627737 | HeLa | viability after 15 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.06376971222669206 | [416] | [216,158,153] | 0 | hSpCas9 | negative selection | 1621618 | 48543339 | 48543362 | 17 | + | 26627737 | HeLa | viability after 18 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.13024568662028108 | [416] | [155,138,153] | 1 | hSpCas9 | negative selection | 1703933 | 48543339 | 48543362 | 17 | + | 26627737 | HCT116 | viability after 6 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | -0.616047933460349 | [508] | [135,5] | -4 | hSpCas9 | negative selection | 1786248 | 48543339 | 48543362 | 17 | + | 26627737 | HCT116 | viability after 8 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | -0.052211169661840334 | [257] | [120,148,140] | 0 | hSpCas9 | negative selection | 1868563 | 48543339 | 48543362 | 17 | + | 26627737 | HCT116 | viability after 9 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.9208109714920358 | [508] | [96,383] | 6 | hSpCas9 | negative selection | 1950878 | 48543339 | 48543362 | 17 | + | 26627737 | HCT116 | viability after 12 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | -0.17361147365323434 | [257] | [84,89,187] | -2 | hSpCas9 | negative selection | 2033193 | 48543339 | 48543362 | 17 | + | 26627737 | HCT116 | viability after 15 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | -0.15521413343989401 | [257] | [131,130,135] | -2 | hSpCas9 | negative selection | 2115508 | 48543339 | 48543362 | 17 | + | 26627737 | HCT116 | viability after 18 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.36024471150884596 | [257] | [118,136,228] | 3 | hSpCas9 | negative selection | 2197823 | 48543448 | 48543471 | 17 | + | 27260157 | DLD1 | viability | TGGCCGCGGGTTCCTCGGCAGGG | HOXB2 | ENSG00000173917 | -0.333213714872756 | [] | [] | -3 | hSpCas9 | negative selection | 2577414 | 48543508 | 48543531 | 17 | - | 27260157 | DLD1 | viability | GCACCGAGAGCCGCCGGATGGGG | HOXB2 | ENSG00000173917 | -0.302513647786328 | [] | [] | -2 | hSpCas9 | negative selection | 2647816 | 48543448 | 48543471 | 17 | + | 27260157 | HT1080 | viability | TGGCCGCGGGTTCCTCGGCAGGG | HOXB2 | ENSG00000173917 | 0.150729480253697 | [] | [] | 1 | hSpCas9 | negative selection | 2653544 | 48543508 | 48543531 | 17 | - | 27260157 | HT1080 | viability | GCACCGAGAGCCGCCGGATGGGG | HOXB2 | ENSG00000173917 | -0.883532474232506 | [] | [] | -8 | hSpCas9 | negative selection | 2723946 | 48543448 | 48543471 | 17 | + | 27260157 | MKN45 | viability | TGGCCGCGGGTTCCTCGGCAGGG | HOXB2 | ENSG00000173917 | -0.0239727210537541 | [] | [] | 0 | hSpCas9 | negative selection | 2729674 | 48543508 | 48543531 | 17 | - | 27260157 | MKN45 | viability | GCACCGAGAGCCGCCGGATGGGG | HOXB2 | ENSG00000173917 | 0.140924893083731 | [] | [] | 5 | hSpCas9 | negative selection | 2800076 | 48543448 | 48543471 | 17 | + | 27260157 | RKO | viability | TGGCCGCGGGTTCCTCGGCAGGG | HOXB2 | ENSG00000173917 | 0.223067922553497 | [] | [] | 1 | hSpCas9 | negative selection | 2805804 | 48543508 | 48543531 | 17 | - | 27260157 | RKO | viability | GCACCGAGAGCCGCCGGATGGGG | HOXB2 | ENSG00000173917 | -0.330554736167237 | [] | [] | -6 | hSpCas9 | negative selection | 2876206 | 48543448 | 48543471 | 17 | + | 27260157 | SF268 | viability | TGGCCGCGGGTTCCTCGGCAGGG | HOXB2 | ENSG00000173917 | -0.229289226027064 | [] | [] | -2 | hSpCas9 | negative selection | 2881934 | 48543508 | 48543531 | 17 | - | 27260157 | SF268 | viability | GCACCGAGAGCCGCCGGATGGGG | HOXB2 | ENSG00000173917 | -0.150721075931164 | [] | [] | -1 | hSpCas9 | negative selection | 2952336 | 48543334 | 48543357 | 17 | - | 27383988 | 293T | resistance to West Nile virus (flavivirus) | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 2.236845507961646 | [25,38] | [0,0] | 7 | hSpCas9 | positive selection | 3353917 | 48543199 | 48543222 | 17 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.5024387092823666 | [107,107] | [0,0] | 2 | hSpCas9 | positive selection | 3373128 | 48543199 | 48543222 | 17 | + | 26780180 | A375 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 1.04151748300166 | [] | [] | 5 | hSpCas9 | negative selection | 3948792 | 48543334 | 48543357 | 17 | - | 26780180 | A375 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.818579334893141 | [] | [] | 3 | hSpCas9 | negative selection | 3948793 | 48543199 | 48543222 | 17 | + | 26780180 | HT29 | viability (GeCKOv2 library) | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 1.20063210951174 | [] | [] | 6 | hSpCas9 | negative selection | 4056758 | 48543334 | 48543357 | 17 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.408270909993875 | [] | [] | 1 | hSpCas9 | negative selection | 4056759 | 48543334 | 48543357 | 17 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | -0.04514101956929217 | [1] | [2,0] | -1 | hSpCas9 | positive selection | 4275612 | 48543199 | 48543222 | 17 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.998396007138019 | [2] | [2,5] | 9 | hSpCas9 | positive selection | 4339872 | 48543334 | 48543357 | 17 | - | 27260156 | BXPC3 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.24636849946165285 | [171] | [196,227,244,178] | 5 | hSpCas9 | negative selection | 5548072 | 48543199 | 48543222 | 17 | + | 27260156 | BXPC3 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.18697715559663297 | [269] | [299,252,427,308] | 4 | hSpCas9 | negative selection | 5612332 | 48543334 | 48543357 | 17 | - | 27260156 | A673 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | -0.03151913678818197 | [171] | [269,206,182,152] | -1 | hSpCas9 | negative selection | 5669323 | 48543199 | 48543222 | 17 | + | 27260156 | A673 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.028768494907158937 | [269] | [338,320,296,315] | 0 | hSpCas9 | negative selection | 5733583 | 48543334 | 48543357 | 17 | - | 27260156 | A375 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.7124107423750309 | [171] | [360,429,341,210] | 9 | hSpCas9 | negative selection | 5790574 | 48543199 | 48543222 | 17 | + | 27260156 | A375 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.3504384063240609 | [269] | [276,414,498,414] | 5 | hSpCas9 | negative selection | 5854834 | 48543334 | 48543357 | 17 | - | 27260156 | COLO741 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.5464033155795063 | [171] | [282,354,320] | 9 | hSpCas9 | negative selection | 5911825 | 48543199 | 48543222 | 17 | + | 27260156 | COLO741 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.12951351582990744 | [269] | [437,427,277] | 2 | hSpCas9 | negative selection | 5976085 | 48543334 | 48543357 | 17 | - | 27260156 | CAL120 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.08643000266022471 | [171] | [349,171,178] | 1 | hSpCas9 | negative selection | 6033076 | 48543199 | 48543222 | 17 | + | 27260156 | CAL120 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.4411495995137939 | [269] | [425,606,332] | 6 | hSpCas9 | negative selection | 6097336 | 48543334 | 48543357 | 17 | - | 27260156 | CADOES1 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.41124918613479733 | [171] | [160,190,209,291] | 6 | hSpCas9 | negative selection | 6154327 | 48543199 | 48543222 | 17 | + | 27260156 | CADOES1 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.0926083712372392 | [269] | [142,284,261,252] | -1 | hSpCas9 | negative selection | 6218587 | 48543334 | 48543357 | 17 | - | 27260156 | EWS502 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.2579656377676942 | [171] | [185,216,188,286] | 4 | hSpCas9 | negative selection | 6275578 | 48543199 | 48543222 | 17 | + | 27260156 | EWS502 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.3903630965267328 | [269] | [461,278,346,404] | 6 | hSpCas9 | negative selection | 6339838 | 48543334 | 48543357 | 17 | - | 27260156 | EW8 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.1644456578747231 | [171] | [280,127,97,140] | 3 | hSpCas9 | negative selection | 6396829 | 48543199 | 48543222 | 17 | + | 27260156 | EW8 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.27867137562102795 | [269] | [355,187,244,284] | 5 | hSpCas9 | negative selection | 6461089 | 48543334 | 48543357 | 17 | - | 27260156 | CORL105 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | -0.04154865996297041 | [171] | [197,187,184,209] | -1 | hSpCas9 | negative selection | 6518080 | 48543199 | 48543222 | 17 | + | 27260156 | CORL105 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.1546849695922874 | [269] | [519,167,397,337] | 3 | hSpCas9 | negative selection | 6582340 | 48543334 | 48543357 | 17 | - | 27260156 | HS294T | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.5986445385927485 | [171] | [39,84,92,208] | 7 | hSpCas9 | negative selection | 6639331 | 48543199 | 48543222 | 17 | + | 27260156 | HS294T | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.42108144822173577 | [269] | [107,39,73,89] | -5 | hSpCas9 | negative selection | 6703591 | 48543334 | 48543357 | 17 | - | 27260156 | HCC44 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.6052727801490018 | [171] | [167,249,251,491] | 8 | hSpCas9 | negative selection | 6760582 | 48543199 | 48543222 | 17 | + | 27260156 | HCC44 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.2915454600201822 | [269] | [449,313,385,359] | 5 | hSpCas9 | negative selection | 6824842 | 48543334 | 48543357 | 17 | - | 27260156 | G402 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.6106369497588524 | [171] | [380,468,148,299] | 7 | hSpCas9 | negative selection | 6881833 | 48543199 | 48543222 | 17 | + | 27260156 | G402 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.09198656501843605 | [269] | [294,517,371,225] | 1 | hSpCas9 | negative selection | 6946093 | 48543334 | 48543357 | 17 | - | 27260156 | L33 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | -0.07910862911420757 | [171] | [149,69,107,158] | -2 | hSpCas9 | negative selection | 7003084 | 48543199 | 48543222 | 17 | + | 27260156 | L33 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.0310154864300326 | [269] | [390,105,139,181] | 0 | hSpCas9 | negative selection | 7067344 | 48543334 | 48543357 | 17 | - | 27260156 | K562 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | -0.39930718706380897 | [171] | [206,110,57,95] | -5 | hSpCas9 | negative selection | 7124335 | 48543199 | 48543222 | 17 | + | 27260156 | K562 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.0944841716668452 | [269] | [148,348,298,224] | 1 | hSpCas9 | negative selection | 7188595 | 48543334 | 48543357 | 17 | - | 27260156 | HT29 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.17816823124895032 | [171] | [275,150,148,349] | 3 | hSpCas9 | negative selection | 7245586 | 48543199 | 48543222 | 17 | + | 27260156 | HT29 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.3052959087648883 | [269] | [385,406,437,388] | 6 | hSpCas9 | negative selection | 7309846 | 48543334 | 48543357 | 17 | - | 27260156 | MHHES1 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.3512739707195316 | [171] | [355,388,194,103] | 6 | hSpCas9 | negative selection | 7366837 | 48543199 | 48543222 | 17 | + | 27260156 | MHHES1 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.2980324993677341 | [269] | [135,198,448,194] | -5 | hSpCas9 | negative selection | 7431097 | 48543334 | 48543357 | 17 | - | 27260156 | MEWO | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.10487844938304436 | [171] | [183,220,115] | 2 | hSpCas9 | negative selection | 7488088 | 48543199 | 48543222 | 17 | + | 27260156 | MEWO | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.18371543252423028 | [269] | [328,247,291] | 4 | hSpCas9 | negative selection | 7552348 | 48543334 | 48543357 | 17 | - | 27260156 | LNCAPCLONEFGC | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.2979356760969092 | [171] | [253,187,217,108] | 5 | hSpCas9 | negative selection | 7609339 | 48543199 | 48543222 | 17 | + | 27260156 | LNCAPCLONEFGC | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.26055716701552123 | [269] | [258,353,323,235] | 4 | hSpCas9 | negative selection | 7673599 | 48543334 | 48543357 | 17 | - | 27260156 | PANC0327 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.5370959748289579 | [171] | [246,181,248,215] | 7 | hSpCas9 | negative selection | 7730590 | 48543199 | 48543222 | 17 | + | 27260156 | PANC0327 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.187066364767004 | [269] | [360,93,196,217] | -3 | hSpCas9 | negative selection | 7794850 | 48543334 | 48543357 | 17 | - | 27260156 | NCIH2009 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.7487603920763154 | [171] | [303,348,538] | 8 | hSpCas9 | negative selection | 7851841 | 48543199 | 48543222 | 17 | + | 27260156 | NCIH2009 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.01671632793519051 | [269] | [558,397,221] | 0 | hSpCas9 | negative selection | 7916101 | 48543334 | 48543357 | 17 | - | 27260156 | NCIH1373 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.9796790709209473 | [171] | [325,162,199,230] | 8 | hSpCas9 | negative selection | 7973092 | 48543199 | 48543222 | 17 | + | 27260156 | NCIH1373 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.1964266252376632 | [269] | [366,283,209,53] | -2 | hSpCas9 | negative selection | 8037352 | 48543334 | 48543357 | 17 | - | 27260156 | PATU8902 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.1213166111424222 | [171] | [473,202,172,202] | 1 | hSpCas9 | negative selection | 8094343 | 48543199 | 48543222 | 17 | + | 27260156 | PATU8902 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.5111991573404653 | [269] | [267,427,183,184] | -5 | hSpCas9 | negative selection | 8158603 | 48543334 | 48543357 | 17 | - | 27260156 | PANC1 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.389604902717408 | [171] | [252,242,162,130] | 6 | hSpCas9 | negative selection | 8215594 | 48543199 | 48543222 | 17 | + | 27260156 | PANC1 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.4632200697229789 | [269] | [203,222,118,138] | -6 | hSpCas9 | negative selection | 8279854 | 48543334 | 48543357 | 17 | - | 27260156 | PANC0813 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.33710233661834965 | [171] | [168,321,377,149] | 5 | hSpCas9 | negative selection | 8336845 | 48543199 | 48543222 | 17 | + | 27260156 | PANC0813 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.3784457717306957 | [269] | [261,289,200,224] | -5 | hSpCas9 | negative selection | 8401105 | 48543334 | 48543357 | 17 | - | 27260156 | RDES | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.5377339823694322 | [171] | [217,243,263,458] | 8 | hSpCas9 | negative selection | 8458096 | 48543199 | 48543222 | 17 | + | 27260156 | RDES | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.17428072501927205 | [269] | [203,413,448,354] | 3 | hSpCas9 | negative selection | 8522356 | 48543334 | 48543357 | 17 | - | 27260156 | PC3 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.2975860615813717 | [171] | [128,232,278,243] | 6 | hSpCas9 | negative selection | 8579347 | 48543199 | 48543222 | 17 | + | 27260156 | PC3 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.356606490235052 | [269] | [201,411,605,283] | 7 | hSpCas9 | negative selection | 8643607 | 48543334 | 48543357 | 17 | - | 27260156 | PATU8988T | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.36457969196624895 | [171] | [157,293,193,217] | 6 | hSpCas9 | negative selection | 8700598 | 48543199 | 48543222 | 17 | + | 27260156 | PATU8988T | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.1129964636641283 | [269] | [114,203,293,356] | -2 | hSpCas9 | negative selection | 8764858 | 48543334 | 48543357 | 17 | - | 27260156 | T47D | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.12160301249767591 | [171] | [203,220,216,229] | 2 | hSpCas9 | negative selection | 8821849 | 48543199 | 48543222 | 17 | + | 27260156 | T47D | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.07292886901685924 | [269] | [273,283,331,306] | -2 | hSpCas9 | negative selection | 8886109 | 48543334 | 48543357 | 17 | - | 27260156 | SU8686 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.9396939297160176 | [171] | [382,252,207,487] | 9 | hSpCas9 | negative selection | 8943100 | 48543199 | 48543222 | 17 | + | 27260156 | SU8686 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.18838444139123867 | [269] | [181,239,329,185] | -3 | hSpCas9 | negative selection | 9007360 | 48543334 | 48543357 | 17 | - | 27260156 | SKES1 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.31818893507454793 | [171] | [265,321,109,180] | 6 | hSpCas9 | negative selection | 9064351 | 48543199 | 48543222 | 17 | + | 27260156 | SKES1 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.10224101240009498 | [269] | [340,412,242,190] | 2 | hSpCas9 | negative selection | 9128611 | 48543334 | 48543357 | 17 | - | 27260156 | TOV112D | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.3576036600096508 | [171] | [160,391,230,137] | 6 | hSpCas9 | negative selection | 9185602 | 48543199 | 48543222 | 17 | + | 27260156 | TOV112D | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.05482628327629202 | [269] | [176,346,117,408] | -1 | hSpCas9 | negative selection | 9249862 | 48543334 | 48543357 | 17 | - | 27260156 | TC71 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | -0.2446313381278058 | [171] | [172,136,126,187] | -6 | hSpCas9 | negative selection | 9306853 | 48543199 | 48543222 | 17 | + | 27260156 | TC71 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | 0.1987692765606779 | [269] | [290,305,322,414] | 5 | hSpCas9 | negative selection | 9371113 | 48543334 | 48543357 | 17 | - | 27260156 | TC32 | viability | GCCTTTAGCCGTTCGCTTAGAGG | HOXB2 | ENSG00000173917 | 0.7525070401065465 | [171] | [322,138,389,286] | 9 | hSpCas9 | negative selection | 9428104 | 48543199 | 48543222 | 17 | + | 27260156 | TC32 | viability | AGTCGGCCGCGAAGAAGTTGAGG | HOXB2 | ENSG00000173917 | -0.014313812348845989 | [269] | [308,115,315,307] | 0 | hSpCas9 | negative selection | 9492364 | 48543339 | 48543362 | 17 | + | 27869803 | HPAFII | viability after 27 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 1.1009120572612652 | [140] | [206,118,NaN] | 8 | hSpCas9 | negative selection | 9561486 | 48543339 | 48543362 | 17 | + | 27869803 | HPAFII | viability after 15 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.7973594388111251 | [140] | [353,206,NaN] | 8 | hSpCas9 | negative selection | 9643935 | 48543339 | 48543362 | 17 | + | 27869803 | ASPC1 | viability after 36 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.8065489335976703 | [467] | [598,262,80] | 7 | hSpCas9 | negative selection | 9726384 | 48543339 | 48543362 | 17 | + | 27869803 | PATU8988S | viability after 35 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.8563239821862088 | [460] | [395,275,NaN] | 8 | hSpCas9 | negative selection | 9808833 | 48543339 | 48543362 | 17 | + | 27869803 | PATU8988S | viability after 31 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.6839560198621393 | [460] | [271,324,NaN] | 7 | hSpCas9 | negative selection | 9891282 | 48543339 | 48543362 | 17 | + | 27869803 | HPAFII | viability after 35 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 0.562582014889988 | [140] | [127,79,NaN] | 3 | hSpCas9 | negative selection | 9973731 | 48543339 | 48543362 | 17 | + | 27869803 | HPAFII | viability after 31 days | AAGCGAACGGCTAAAGGCCGGGG | HOXB2 | ENSG00000173917 | 1.178498910718403 | [140] | [214,139,NaN] | 8 | hSpCas9 | negative selection | 10056180 |