Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:55806
• Symbol:HR
• Description:HR lysine demethylase and nuclear receptor corepressor

DataSource: http://genomecrispr.dkfz.de/#!/results/HR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
22128874	22128897	8	-	26472758	Jiyoye	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.5390870570114545	[93]	[102]	4	hSpCas9	negative selection	74003
22127454	22127477	8	+	26472758	Jiyoye	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	1.0015365802292793	[50]	[76]	6	hSpCas9	negative selection	74004
22127394	22127417	8	-	26472758	Jiyoye	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.2028781001781133	[115]	[37]	-7	hSpCas9	negative selection	74005
22125581	22125604	8	-	26472758	Jiyoye	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.2493403802403168	[185]	[117]	-2	hSpCas9	negative selection	74006
22129143	22129166	8	-	26472758	Jiyoye	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	3.0930667910778107	[22]	[147]	9	hSpCas9	negative selection	74007
22129031	22129054	8	+	26472758	Jiyoye	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.4089604260939404	[205]	[116]	-3	hSpCas9	negative selection	74008
22128939	22128962	8	-	26472758	Jiyoye	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	0.42509728950313597	[79]	[80]	3	hSpCas9	negative selection	74009
22128812	22128835	8	-	26472758	Jiyoye	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.6702097873396672	[74]	[89]	5	hSpCas9	negative selection	74010
22128600	22128623	8	-	26472758	Jiyoye	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	0.5173582992562964	[188]	[203]	4	hSpCas9	negative selection	74011
22127521	22127544	8	-	26472758	Jiyoye	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	0.7291034763932358	[15]	[19]	5	hSpCas9	negative selection	74012
22128874	22128897	8	-	26472758	KBM7	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.6806590476491835	[295,345]	[253,236]	7	hSpCas9	negative selection	265121
22127454	22127477	8	+	26472758	KBM7	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.12372795613008623	[528,374]	[206,247]	1	hSpCas9	negative selection	265122
22127394	22127417	8	-	26472758	KBM7	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.5055191633460656	[588,323]	[78,68]	-8	hSpCas9	negative selection	265123
22125581	22125604	8	-	26472758	KBM7	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.5650117552665781	[784,488]	[233,166]	-5	hSpCas9	negative selection	265124
22129143	22129166	8	-	26472758	KBM7	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.15443414354845955	[642,337]	[272,228]	1	hSpCas9	negative selection	265125
22129031	22129054	8	+	26472758	KBM7	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.14847058311175773	[672,299]	[247,241]	1	hSpCas9	negative selection	265126
22128939	22128962	8	-	26472758	KBM7	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-1.9806611453343033	[368,258]	[28,43]	-8	hSpCas9	negative selection	265127
22128812	22128835	8	-	26472758	KBM7	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	1.2124808631040944	[297,330]	[304,382]	9	hSpCas9	negative selection	265128
22128600	22128623	8	-	26472758	KBM7	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.22580464926037852	[752,467]	[272,211]	-2	hSpCas9	negative selection	265129
22127521	22127544	8	-	26472758	KBM7	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-0.15930300264734765	[97,144]	[53,50]	-1	hSpCas9	negative selection	265130
22128874	22128897	8	-	26472758	Raji	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.8443491295398057	[107]	[44]	7	hSpCas9	negative selection	456239
22127454	22127477	8	+	26472758	Raji	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	-0.7056850378783983	[252]	[35]	-5	hSpCas9	negative selection	456240
22127394	22127417	8	-	26472758	Raji	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-2.2734382485673312	[124]	[5]	-9	hSpCas9	negative selection	456241
22125581	22125604	8	-	26472758	Raji	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.03506072964660592	[233]	[52]	0	hSpCas9	negative selection	456242
22129143	22129166	8	-	26472758	Raji	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.6622440043053365	[225]	[82]	6	hSpCas9	negative selection	456243
22129031	22129054	8	+	26472758	Raji	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.32433270505187467	[231]	[42]	-3	hSpCas9	negative selection	456244
22128939	22128962	8	-	26472758	Raji	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	0.434193851640708	[117]	[36]	4	hSpCas9	negative selection	456245
22128812	22128835	8	-	26472758	Raji	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	1.4491720526218046	[100]	[63]	9	hSpCas9	negative selection	456246
22128600	22128623	8	-	26472758	Raji	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	0.7976301544323394	[294]	[118]	7	hSpCas9	negative selection	456247
22127521	22127544	8	-	26472758	Raji	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	1.08272148113933	[58]	[28]	8	hSpCas9	negative selection	456248
22128874	22128897	8	-	26472758	K562	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.10350457575385996	[279]	[219]	0	hSpCas9	negative selection	647357
22127454	22127477	8	+	26472758	K562	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.15492057682734434	[265]	[249]	1	hSpCas9	negative selection	647358
22127394	22127417	8	-	26472758	K562	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-2.2018375022231167	[217]	[39]	-7	hSpCas9	negative selection	647359
22125581	22125604	8	-	26472758	K562	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.6297497201291004	[551]	[720]	5	hSpCas9	negative selection	647360
22129143	22129166	8	-	26472758	K562	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.04448115715769496	[339]	[295]	0	hSpCas9	negative selection	647361
22129031	22129054	8	+	26472758	K562	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.47264730906205443	[359]	[218]	-3	hSpCas9	negative selection	647362
22128939	22128962	8	-	26472758	K562	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-0.3372234147630978	[216]	[144]	-2	hSpCas9	negative selection	647363
22128812	22128835	8	-	26472758	K562	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.1521039776827674	[241]	[226]	1	hSpCas9	negative selection	647364
22128600	22128623	8	-	26472758	K562	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.6062585234419027	[430]	[238]	-4	hSpCas9	negative selection	647365
22127521	22127544	8	-	26472758	K562	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	1.1791272674147277	[112]	[215]	8	hSpCas9	negative selection	647366
22122550	22122573	8	-	26627737	DLD1	viability	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.882501973829602	[149]	[30,30,15]	-7	hSpCas9	negative selection	838985
22123780	22123803	8	-	26627737	DLD1	viability	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.678674016609378	[537]	[330,310,180]	6	hSpCas9	negative selection	838986
22125403	22125426	8	-	26627737	DLD1	viability	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.10401026202591745	[247]	[42,15,173]	1	hSpCas9	negative selection	838987
22125581	22125604	8	-	26627737	DLD1	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.2489490188454856	[394]	[106,108,96]	-3	hSpCas9	negative selection	838988
22127435	22127458	8	-	26627737	DLD1	viability	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.15963444182681732	[579]	[199,179,114]	-2	hSpCas9	negative selection	838989
22129058	22129081	8	+	26627737	DLD1	viability	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.030239915280313	[960]	[443,314,180]	0	hSpCas9	negative selection	838990
22122550	22122573	8	-	26627737	GBM cells	viability after 5 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	0.007848246438849849	[50]	[13,40]	0	hSpCas9	negative selection	921300
22123780	22123803	8	-	26627737	GBM cells	viability after 5 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.2351183428605501	[180]	[279,176]	9	hSpCas9	negative selection	921301
22125403	22125426	8	-	26627737	GBM cells	viability after 5 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-0.5624172766670932	[94]	[39,28]	-7	hSpCas9	negative selection	921302
22125581	22125604	8	-	26627737	GBM cells	viability after 5 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.09685325249759458	[135]	[47,107]	1	hSpCas9	negative selection	921303
22127435	22127458	8	-	26627737	GBM cells	viability after 5 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.1572717935100063	[514]	[352,262]	2	hSpCas9	negative selection	921304
22129058	22129081	8	+	26627737	GBM cells	viability after 5 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.10392421799389723	[333]	[201,182]	1	hSpCas9	negative selection	921305
22122550	22122573	8	-	26627737	GBM cells	viability after 13 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	0.618569428921228	[50]	[47,37]	7	hSpCas9	negative selection	1003615
22123780	22123803	8	-	26627737	GBM cells	viability after 13 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.0373669960002667	[180]	[232,175]	9	hSpCas9	negative selection	1003616
22125403	22125426	8	-	26627737	GBM cells	viability after 13 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-0.084344316710526	[94]	[41,53]	-1	hSpCas9	negative selection	1003617
22125581	22125604	8	-	26627737	GBM cells	viability after 13 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.3731794737226689	[135]	[67,117]	5	hSpCas9	negative selection	1003618
22127435	22127458	8	-	26627737	GBM cells	viability after 13 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.14214770048026004	[514]	[341,280]	1	hSpCas9	negative selection	1003619
22129058	22129081	8	+	26627737	GBM cells	viability after 13 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.3644958906590559	[333]	[304,174]	4	hSpCas9	negative selection	1003620
22122550	22122573	8	-	26627737	GBM cells	viability after 21 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	1.4754269825173218	[50]	[75,77]	9	hSpCas9	negative selection	1085930
22123780	22123803	8	-	26627737	GBM cells	viability after 21 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.5937887025032755	[180]	[312,281]	9	hSpCas9	negative selection	1085931
22125403	22125426	8	-	26627737	GBM cells	viability after 21 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.0917374048093702	[94]	[54,54]	1	hSpCas9	negative selection	1085932
22125581	22125604	8	-	26627737	GBM cells	viability after 21 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.06599622165232844	[135]	[80,73]	0	hSpCas9	negative selection	1085933
22127435	22127458	8	-	26627737	GBM cells	viability after 21 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.28089432785253743	[514]	[246,214]	-3	hSpCas9	negative selection	1085934
22129058	22129081	8	+	26627737	GBM cells	viability after 21 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.07404100288068449	[333]	[186,158]	0	hSpCas9	negative selection	1085935
22122550	22122573	8	-	26627737	RPE1	viability after 9 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.8942285848157783	[393]	[61,71]	-6	hSpCas9	negative selection	1168245
22123780	22123803	8	-	26627737	RPE1	viability after 9 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.30389577784454197	[688]	[281,245]	2	hSpCas9	negative selection	1168246
22125403	22125426	8	-	26627737	RPE1	viability after 9 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-2.217253607701605	[663]	[52,33]	-9	hSpCas9	negative selection	1168247
22125581	22125604	8	-	26627737	RPE1	viability after 9 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-1.1553264835879804	[439]	[108,0]	-7	hSpCas9	negative selection	1168248
22127435	22127458	8	-	26627737	RPE1	viability after 9 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.23435432213518947	[1245]	[278,690]	1	hSpCas9	negative selection	1168249
22129058	22129081	8	+	26627737	RPE1	viability after 9 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.906344513774396	[767]	[112,147]	-6	hSpCas9	negative selection	1168250
22122550	22122573	8	-	26627737	RPE1	viability after 12 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-1.8679594126556667	[393]	[45,10]	-8	hSpCas9	negative selection	1250560
22123780	22123803	8	-	26627737	RPE1	viability after 12 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.038040675311149	[688]	[451,303]	6	hSpCas9	negative selection	1250561
22125403	22125426	8	-	26627737	RPE1	viability after 12 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-3.4159182221479867	[663]	[23,8]	-9	hSpCas9	negative selection	1250562
22125581	22125604	8	-	26627737	RPE1	viability after 12 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-1.2977118574665392	[439]	[84,8]	-7	hSpCas9	negative selection	1250563
22127435	22127458	8	-	26627737	RPE1	viability after 12 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.19207941167708953	[1245]	[276,309]	-1	hSpCas9	negative selection	1250564
22129058	22129081	8	+	26627737	RPE1	viability after 12 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.10296298211380761	[767]	[190,253]	0	hSpCas9	negative selection	1250565
22122550	22122573	8	-	26627737	RPE1	viability after 15 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-2.156446755809757	[393]	[24,24]	-8	hSpCas9	negative selection	1332875
22123780	22123803	8	-	26627737	RPE1	viability after 15 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.07520744240445927	[688]	[270,141]	0	hSpCas9	negative selection	1332876
22125403	22125426	8	-	26627737	RPE1	viability after 15 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-3.022791533245872	[663]	[44,1]	-9	hSpCas9	negative selection	1332877
22125581	22125604	8	-	26627737	RPE1	viability after 15 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-2.386666314864532	[439]	[34,12]	-8	hSpCas9	negative selection	1332878
22127435	22127458	8	-	26627737	RPE1	viability after 15 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.25140536525950963	[1245]	[415,422]	1	hSpCas9	negative selection	1332879
22129058	22129081	8	+	26627737	RPE1	viability after 15 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.29060088721623856	[767]	[142,210]	-2	hSpCas9	negative selection	1332880
22122550	22122573	8	-	26627737	RPE1	viability after 18 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.9714311190289067	[393]	[89,15]	-6	hSpCas9	negative selection	1415190
22123780	22123803	8	-	26627737	RPE1	viability after 18 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.5249459724162457	[688]	[195,343]	3	hSpCas9	negative selection	1415191
22125403	22125426	8	-	26627737	RPE1	viability after 18 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-2.699666922157721	[663]	[29,24]	-9	hSpCas9	negative selection	1415192
22125581	22125604	8	-	26627737	RPE1	viability after 18 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-1.7166474813565915	[439]	[68,0]	-8	hSpCas9	negative selection	1415193
22127435	22127458	8	-	26627737	RPE1	viability after 18 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.08102594651843242	[1245]	[258,458]	0	hSpCas9	negative selection	1415194
22129058	22129081	8	+	26627737	RPE1	viability after 18 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.024508172609345433	[767]	[248,169]	0	hSpCas9	negative selection	1415195
22122550	22122573	8	-	26627737	HeLa	viability after 8 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	0.8778479711759034	[111]	[129,93,55]	7	hSpCas9	negative selection	1497505
22123780	22123803	8	-	26627737	HeLa	viability after 8 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.5170178715084148	[505]	[430,198,338]	4	hSpCas9	negative selection	1497506
22125403	22125426	8	-	26627737	HeLa	viability after 8 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.8624346869168097	[143]	[61,104,159]	7	hSpCas9	negative selection	1497507
22125581	22125604	8	-	26627737	HeLa	viability after 8 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.45654649450091467	[251]	[44,288,97]	4	hSpCas9	negative selection	1497508
22127435	22127458	8	-	26627737	HeLa	viability after 8 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.45451866427771115	[857]	[329,256,244]	-4	hSpCas9	negative selection	1497509
22129058	22129081	8	+	26627737	HeLa	viability after 8 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.24951765748556054	[642]	[378,502,139]	2	hSpCas9	negative selection	1497510
22122550	22122573	8	-	26627737	HeLa	viability after 12 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	0.2191813384678707	[111]	[96,33,33]	2	hSpCas9	negative selection	1579820
22123780	22123803	8	-	26627737	HeLa	viability after 12 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.0317723745183107	[505]	[619,353,321]	7	hSpCas9	negative selection	1579821
22125403	22125426	8	-	26627737	HeLa	viability after 12 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.4697064091784924	[143]	[155,0,100]	4	hSpCas9	negative selection	1579822
22125581	22125604	8	-	26627737	HeLa	viability after 12 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.21979515919652648	[251]	[28,169,156]	2	hSpCas9	negative selection	1579823
22127435	22127458	8	-	26627737	HeLa	viability after 12 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.5558638358883062	[857]	[271,245,205]	-5	hSpCas9	negative selection	1579824
22129058	22129081	8	+	26627737	HeLa	viability after 12 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.2222668378530389	[642]	[79,218,380]	-2	hSpCas9	negative selection	1579825
22122550	22122573	8	-	26627737	HeLa	viability after 15 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.3278625860334874	[111]	[20,53,33]	-3	hSpCas9	negative selection	1662135
22123780	22123803	8	-	26627737	HeLa	viability after 15 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.1039050373549752	[505]	[689,313,310]	7	hSpCas9	negative selection	1662136
22125403	22125426	8	-	26627737	HeLa	viability after 15 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.6444770403080547	[143]	[164,28,78]	5	hSpCas9	negative selection	1662137
22125581	22125604	8	-	26627737	HeLa	viability after 15 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.8154227800224739	[251]	[35,82,55]	-6	hSpCas9	negative selection	1662138
22127435	22127458	8	-	26627737	HeLa	viability after 15 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.6997077034258561	[857]	[156,272,215]	-6	hSpCas9	negative selection	1662139
22129058	22129081	8	+	26627737	HeLa	viability after 15 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.10944422943432386	[642]	[145,419,282]	1	hSpCas9	negative selection	1662140
22122550	22122573	8	-	26627737	HeLa	viability after 18 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.2848387761521425	[111]	[11,49,33]	-2	hSpCas9	negative selection	1744450
22123780	22123803	8	-	26627737	HeLa	viability after 18 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.1159696633457417	[505]	[470,258,310]	7	hSpCas9	negative selection	1744451
22125403	22125426	8	-	26627737	HeLa	viability after 18 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.6074228067346172	[143]	[106,22,78]	5	hSpCas9	negative selection	1744452
22125581	22125604	8	-	26627737	HeLa	viability after 18 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.7844062125590329	[251]	[23,71,55]	-6	hSpCas9	negative selection	1744453
22127435	22127458	8	-	26627737	HeLa	viability after 18 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.6622035043445593	[857]	[105,238,215]	-5	hSpCas9	negative selection	1744454
22129058	22129081	8	+	26627737	HeLa	viability after 18 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.11002756181603435	[642]	[105,337,282]	1	hSpCas9	negative selection	1744455
22122550	22122573	8	-	26627737	HCT116	viability after 6 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-1.581159858294353	[301]	[11,17]	-7	hSpCas9	negative selection	1826765
22123780	22123803	8	-	26627737	HCT116	viability after 6 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	-1.0282588339345382	[1884]	[250,86]	-5	hSpCas9	negative selection	1826766
22125403	22125426	8	-	26627737	HCT116	viability after 6 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	1.0606194627839893	[344]	[281,19]	6	hSpCas9	negative selection	1826767
22125581	22125604	8	-	26627737	HCT116	viability after 6 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.3587620052979963	[271]	[91,0]	-2	hSpCas9	negative selection	1826768
22127435	22127458	8	-	26627737	HCT116	viability after 6 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.02426550569888475	[880]	[63,175]	0	hSpCas9	negative selection	1826769
22129058	22129081	8	+	26627737	HCT116	viability after 6 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.2192193533766046	[935]	[108,135]	-1	hSpCas9	negative selection	1826770
22122550	22122573	8	-	26627737	HCT116	viability after 8 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.28649312740835997	[59]	[17,22,39]	-3	hSpCas9	negative selection	1909080
22123780	22123803	8	-	26627737	HCT116	viability after 8 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.4277639280108953	[290]	[214,210,220]	4	hSpCas9	negative selection	1909081
22125403	22125426	8	-	26627737	HCT116	viability after 8 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-1.414250228937747	[151]	[16,43,32]	-9	hSpCas9	negative selection	1909082
22125581	22125604	8	-	26627737	HCT116	viability after 8 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.5876608868493364	[266]	[107,97,87]	-6	hSpCas9	negative selection	1909083
22127435	22127458	8	-	26627737	HCT116	viability after 8 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.22521271428721312	[558]	[396,335,347]	2	hSpCas9	negative selection	1909084
22129058	22129081	8	+	26627737	HCT116	viability after 8 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.39317503716405056	[606]	[246,268,247]	-5	hSpCas9	negative selection	1909085
22122550	22122573	8	-	26627737	HCT116	viability after 9 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-1.3973606571374955	[301]	[19,38]	-7	hSpCas9	negative selection	1991395
22123780	22123803	8	-	26627737	HCT116	viability after 9 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	-0.8226402165999751	[1884]	[278,288]	-5	hSpCas9	negative selection	1991396
22125403	22125426	8	-	26627737	HCT116	viability after 9 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	1.6568645000721534	[344]	[261,312]	8	hSpCas9	negative selection	1991397
22125581	22125604	8	-	26627737	HCT116	viability after 9 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-1.7595369909766423	[271]	[40,5]	-8	hSpCas9	negative selection	1991398
22127435	22127458	8	-	26627737	HCT116	viability after 9 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.40422434487722547	[880]	[417,226]	3	hSpCas9	negative selection	1991399
22129058	22129081	8	+	26627737	HCT116	viability after 9 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.1466344118849116	[935]	[370,110]	-1	hSpCas9	negative selection	1991400
22122550	22122573	8	-	26627737	HCT116	viability after 12 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-1.5571336915594376	[59]	[2,17,11]	-9	hSpCas9	negative selection	2073710
22123780	22123803	8	-	26627737	HCT116	viability after 12 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.4470489892222411	[290]	[177,244,205]	4	hSpCas9	negative selection	2073711
22125403	22125426	8	-	26627737	HCT116	viability after 12 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-0.23957320890325096	[151]	[47,79,76]	-3	hSpCas9	negative selection	2073712
22125581	22125604	8	-	26627737	HCT116	viability after 12 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.27745284306393914	[266]	[170,55,113]	-3	hSpCas9	negative selection	2073713
22127435	22127458	8	-	26627737	HCT116	viability after 12 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.038391489326016326	[558]	[283,316,305]	0	hSpCas9	negative selection	2073714
22129058	22129081	8	+	26627737	HCT116	viability after 12 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.4567199131336337	[606]	[216,287,194]	-5	hSpCas9	negative selection	2073715
22122550	22122573	8	-	26627737	HCT116	viability after 15 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.9166667372612172	[59]	[19,18,15]	-7	hSpCas9	negative selection	2156025
22123780	22123803	8	-	26627737	HCT116	viability after 15 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.652177957474455	[290]	[240,258,284]	6	hSpCas9	negative selection	2156026
22125403	22125426	8	-	26627737	HCT116	viability after 15 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-2.075581486069007	[151]	[25,34,1]	-9	hSpCas9	negative selection	2156027
22125581	22125604	8	-	26627737	HCT116	viability after 15 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-1.0217852240193415	[266]	[31,174,14]	-7	hSpCas9	negative selection	2156028
22127435	22127458	8	-	26627737	HCT116	viability after 15 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.15398173096276135	[558]	[598,310,192]	1	hSpCas9	negative selection	2156029
22129058	22129081	8	+	26627737	HCT116	viability after 15 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.4611587075163329	[606]	[136,311,295]	-5	hSpCas9	negative selection	2156030
22122550	22122573	8	-	26627737	HCT116	viability after 18 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-1.5531834520907486	[59]	[0,1,27]	-8	hSpCas9	negative selection	2238340
22123780	22123803	8	-	26627737	HCT116	viability after 18 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.8991585436215829	[290]	[242,356,176]	7	hSpCas9	negative selection	2238341
22125403	22125426	8	-	26627737	HCT116	viability after 18 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-0.8813358710706314	[151]	[29,83,0]	-7	hSpCas9	negative selection	2238342
22125581	22125604	8	-	26627737	HCT116	viability after 18 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.318291657896299	[266]	[104,124,77]	-3	hSpCas9	negative selection	2238343
22127435	22127458	8	-	26627737	HCT116	viability after 18 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.16570872079117271	[558]	[243,271,202]	-1	hSpCas9	negative selection	2238344
22129058	22129081	8	+	26627737	HCT116	viability after 18 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.41031662637937716	[606]	[192,235,232]	-4	hSpCas9	negative selection	2238345
22128943	22128966	8	+	24336569	HL60	viability	CACAAGTGGGAGCATGTCCTTGG	HR	ENSG00000168453	-1.1527227837987182	[829]	[789]	-8	hSpCas9	negative selection	2270780
22129031	22129054	8	+	24336569	HL60	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-1.0089160187197312	[794]	[835]	-7	hSpCas9	negative selection	2270781
22129038	22129061	8	+	24336569	HL60	viability	CTCCCAGGCACAGCGGCCCATGG	HR	ENSG00000168453	0.24903988843827982	[368]	[927]	2	hSpCas9	negative selection	2270782
22129054	22129077	8	-	24336569	HL60	viability	CTCGAGATGGACTGCACCATGGG	HR	ENSG00000168453	0.6596974103317883	[617]	[2065]	5	hSpCas9	negative selection	2270783
22129059	22129082	8	+	24336569	HL60	viability	GGTGCAGTCCATCTCGAGGCGGG	HR	ENSG00000168453	-1.3988530359010913	[475]	[381]	-8	hSpCas9	negative selection	2270784
22129066	22129089	8	+	24336569	HL60	viability	TCCATCTCGAGGCGGGCTGCCGG	HR	ENSG00000168453	-0.2825199322489052	[810]	[1410]	-2	hSpCas9	negative selection	2270785
22129085	22129108	8	-	24336569	HL60	viability	GGCATCGTGAGACAGGAGCCCGG	HR	ENSG00000168453	0.1555750966719528	[769]	[1814]	1	hSpCas9	negative selection	2270786
22129092	22129115	8	-	24336569	HL60	viability	AGAGAACGGCATCGTGAGACAGG	HR	ENSG00000168453	-0.44645521605901095	[1916]	[2976]	-4	hSpCas9	negative selection	2270787
22129116	22129139	8	+	24336569	HL60	viability	GGGCCGTCTTCTCCCAGGTTGGG	HR	ENSG00000168453	0.2946197643053714	[182]	[474]	2	hSpCas9	negative selection	2270788
22129142	22129165	8	-	24336569	HL60	viability	AGTACGCCCAGCTTCCTGAAGGG	HR	ENSG00000168453	1.1658251933657102	[356]	[1694]	8	hSpCas9	negative selection	2270789
22128943	22128966	8	+	24336569	KBM7	viability	CACAAGTGGGAGCATGTCCTTGG	HR	ENSG00000168453	-0.1868390319209033	[471]	[1130]	-1	hSpCas9	negative selection	2337957
22129031	22129054	8	+	24336569	KBM7	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.9646756669888952	[653]	[913]	-6	hSpCas9	negative selection	2337958
22129038	22129061	8	+	24336569	KBM7	viability	CTCCCAGGCACAGCGGCCCATGG	HR	ENSG00000168453	-0.4156858607595465	[424]	[868]	-3	hSpCas9	negative selection	2337959
22129054	22129077	8	-	24336569	KBM7	viability	CTCGAGATGGACTGCACCATGGG	HR	ENSG00000168453	0.09602934113023787	[636]	[1856]	0	hSpCas9	negative selection	2337960
22129059	22129082	8	+	24336569	KBM7	viability	GGTGCAGTCCATCTCGAGGCGGG	HR	ENSG00000168453	-0.5429270731363637	[257]	[482]	-4	hSpCas9	negative selection	2337961
22129066	22129089	8	+	24336569	KBM7	viability	TCCATCTCGAGGCGGGCTGCCGG	HR	ENSG00000168453	-0.4158166341640947	[583]	[1193]	-3	hSpCas9	negative selection	2337962
22129085	22129108	8	-	24336569	KBM7	viability	GGCATCGTGAGACAGGAGCCCGG	HR	ENSG00000168453	0.4156697938663213	[574]	[2091]	4	hSpCas9	negative selection	2337963
22129092	22129115	8	-	24336569	KBM7	viability	AGAGAACGGCATCGTGAGACAGG	HR	ENSG00000168453	-0.4793454438551734	[1675]	[3278]	-4	hSpCas9	negative selection	2337964
22129116	22129139	8	+	24336569	KBM7	viability	GGGCCGTCTTCTCCCAGGTTGGG	HR	ENSG00000168453	-0.7657551565751373	[287]	[461]	-5	hSpCas9	negative selection	2337965
22129142	22129165	8	-	24336569	KBM7	viability	AGTACGCCCAGCTTCCTGAAGGG	HR	ENSG00000168453	-0.3552151784002229	[241]	[515]	-3	hSpCas9	negative selection	2337966
22131222	22131245	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAGCTGGCACGCTGCCCCGGGGG	HR	ENSG00000168453	1.808914695859811	[17,9]	[5,15]	6	dCas9-VP64	positive selection	2450162
22131197	22131220	8	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACCCGGGCGCCTGCCGAGAGAGG	HR	ENSG00000168453	6.010812424304557	[4,185]	[7,2873]	9	dCas9-VP64	positive selection	2450163
22131126	22131149	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGGTGGCATCGCCGGGGCGTTGG	HR	ENSG00000168453	2.062612550236288	[10,1]	[9,0]	7	dCas9-VP64	positive selection	2450164
22131222	22131245	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAGCTGGCACGCTGCCCCGGGGG	HR	ENSG00000168453	0.4816966503046688	[42,45]	[24,14]	4	dCas9-VP64	positive selection	2545417
22131197	22131220	8	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACCCGGGCGCCTGCCGAGAGAGG	HR	ENSG00000168453	1.120204505839359	[58,38]	[30,38]	7	dCas9-VP64	positive selection	2545418
22131126	22131149	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGGTGGCATCGCCGGGGCGTTGG	HR	ENSG00000168453	-0.3010962473835214	[115,72]	[37,11]	-3	dCas9-VP64	positive selection	2545419
22129031	22129054	8	+	27260157	DLD1	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.00420627990234583	[]	[]	0	hSpCas9	negative selection	2575399
22129059	22129082	8	+	27260157	DLD1	viability	GGTGCAGTCCATCTCGAGGCGGG	HR	ENSG00000168453	0.324985434274404	[]	[]	4	hSpCas9	negative selection	2577745
22128867	22128890	8	-	27260157	DLD1	viability	AGAGGGACTGCGCTGGAAGGAGG	HR	ENSG00000168453	0.347817443282653	[]	[]	4	hSpCas9	negative selection	2577746
22127797	22127820	8	-	27260157	DLD1	viability	ACAAGGATCCGAGCATTCCCAGG	HR	ENSG00000168453	0.53083865306809	[]	[]	8	hSpCas9	negative selection	2577884
22129094	22129117	8	+	27260157	DLD1	viability	TGTCTCACGATGCCGTTCTCTGG	HR	ENSG00000168453	0.540875797260725	[]	[]	8	hSpCas9	negative selection	2578390
22129092	22129115	8	-	27260157	DLD1	viability	AGAGAACGGCATCGTGAGACAGG	HR	ENSG00000168453	1.14741016609809	[]	[]	9	hSpCas9	negative selection	2581178
22128830	22128853	8	+	27260157	DLD1	viability	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	1.13072784947427	[]	[]	9	hSpCas9	negative selection	2581627
22128846	22128869	8	-	27260157	DLD1	viability	GGCCATGCTTACCCATCCGCTGG	HR	ENSG00000168453	-0.387403024104374	[]	[]	-3	hSpCas9	negative selection	2583979
22127753	22127776	8	-	27260157	DLD1	viability	GCTGCGGAACCTGGGTTGTTTGG	HR	ENSG00000168453	0.10090389338038	[]	[]	3	hSpCas9	negative selection	2584243
22129085	22129108	8	-	27260157	DLD1	viability	GGCATCGTGAGACAGGAGCCCGG	HR	ENSG00000168453	0.559753910084761	[]	[]	8	hSpCas9	negative selection	2584709
22128655	22128678	8	+	27260157	DLD1	viability	GGGCAGGCCAGACACTAGGTAGG	HR	ENSG00000168453	0.186065543391291	[]	[]	3	hSpCas9	negative selection	2604727
22128835	22128858	8	-	27260157	DLD1	viability	CCCATCCGCTGGCATTCTGCGGG	HR	ENSG00000168453	-0.247763096294945	[]	[]	-2	hSpCas9	negative selection	2607692
22129142	22129165	8	-	27260157	DLD1	viability	AGTACGCCCAGCTTCCTGAAGGG	HR	ENSG00000168453	0.376352639742913	[]	[]	4	hSpCas9	negative selection	2609255
22128812	22128835	8	+	27260157	DLD1	viability	CCACAGCGAGGTGGGCACGCTGG	HR	ENSG00000168453	-0.827956734125427	[]	[]	-6	hSpCas9	negative selection	2614754
22129054	22129077	8	-	27260157	DLD1	viability	CTCGAGATGGACTGCACCATGGG	HR	ENSG00000168453	1.27789430714513	[]	[]	9	hSpCas9	negative selection	2621419
22129066	22129089	8	+	27260157	DLD1	viability	TCCATCTCGAGGCGGGCTGCCGG	HR	ENSG00000168453	-0.0433948039341422	[]	[]	0	hSpCas9	negative selection	2623290
22129038	22129061	8	+	27260157	DLD1	viability	CTCCCAGGCACAGCGGCCCATGG	HR	ENSG00000168453	0.745905304901152	[]	[]	8	hSpCas9	negative selection	2641238
22128943	22128966	8	+	27260157	DLD1	viability	CACAAGTGGGAGCATGTCCTTGG	HR	ENSG00000168453	-0.079266473385536	[]	[]	0	hSpCas9	negative selection	2645160
22128667	22128690	8	+	27260157	DLD1	viability	CACTAGGTAGGGTGGCAAGCAGG	HR	ENSG00000168453	-0.414264065409225	[]	[]	-3	hSpCas9	negative selection	2649203
22129031	22129054	8	+	27260157	HT1080	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.498500650785627	[]	[]	4	hSpCas9	negative selection	2651529
22129059	22129082	8	+	27260157	HT1080	viability	GGTGCAGTCCATCTCGAGGCGGG	HR	ENSG00000168453	-0.611421886653962	[]	[]	-8	hSpCas9	negative selection	2653875
22128867	22128890	8	-	27260157	HT1080	viability	AGAGGGACTGCGCTGGAAGGAGG	HR	ENSG00000168453	0.359304282474756	[]	[]	3	hSpCas9	negative selection	2653876
22127797	22127820	8	-	27260157	HT1080	viability	ACAAGGATCCGAGCATTCCCAGG	HR	ENSG00000168453	0.801813110988973	[]	[]	7	hSpCas9	negative selection	2654014
22129094	22129117	8	+	27260157	HT1080	viability	TGTCTCACGATGCCGTTCTCTGG	HR	ENSG00000168453	0.454534242005513	[]	[]	4	hSpCas9	negative selection	2654520
22129092	22129115	8	-	27260157	HT1080	viability	AGAGAACGGCATCGTGAGACAGG	HR	ENSG00000168453	1.7484502018113	[]	[]	9	hSpCas9	negative selection	2657308
22128830	22128853	8	+	27260157	HT1080	viability	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	0.87391818045372	[]	[]	7	hSpCas9	negative selection	2657757
22128846	22128869	8	-	27260157	HT1080	viability	GGCCATGCTTACCCATCCGCTGG	HR	ENSG00000168453	0.0203446741351999	[]	[]	0	hSpCas9	negative selection	2660109
22127753	22127776	8	-	27260157	HT1080	viability	GCTGCGGAACCTGGGTTGTTTGG	HR	ENSG00000168453	-0.524874731275816	[]	[]	-7	hSpCas9	negative selection	2660373
22129085	22129108	8	-	27260157	HT1080	viability	GGCATCGTGAGACAGGAGCCCGG	HR	ENSG00000168453	1.41824823848266	[]	[]	9	hSpCas9	negative selection	2660839
22128655	22128678	8	+	27260157	HT1080	viability	GGGCAGGCCAGACACTAGGTAGG	HR	ENSG00000168453	-0.71129325661016	[]	[]	-8	hSpCas9	negative selection	2680857
22128835	22128858	8	-	27260157	HT1080	viability	CCCATCCGCTGGCATTCTGCGGG	HR	ENSG00000168453	0.273659861374962	[]	[]	2	hSpCas9	negative selection	2683822
22129142	22129165	8	-	27260157	HT1080	viability	AGTACGCCCAGCTTCCTGAAGGG	HR	ENSG00000168453	-0.449388496217286	[]	[]	-7	hSpCas9	negative selection	2685385
22128812	22128835	8	+	27260157	HT1080	viability	CCACAGCGAGGTGGGCACGCTGG	HR	ENSG00000168453	0.679660328868897	[]	[]	6	hSpCas9	negative selection	2690884
22129054	22129077	8	-	27260157	HT1080	viability	CTCGAGATGGACTGCACCATGGG	HR	ENSG00000168453	1.0636439749268	[]	[]	8	hSpCas9	negative selection	2697549
22129066	22129089	8	+	27260157	HT1080	viability	TCCATCTCGAGGCGGGCTGCCGG	HR	ENSG00000168453	0.642266137736703	[]	[]	5	hSpCas9	negative selection	2699420
22129038	22129061	8	+	27260157	HT1080	viability	CTCCCAGGCACAGCGGCCCATGG	HR	ENSG00000168453	0.132560383910416	[]	[]	1	hSpCas9	negative selection	2717368
22128943	22128966	8	+	27260157	HT1080	viability	CACAAGTGGGAGCATGTCCTTGG	HR	ENSG00000168453	0.911176337290842	[]	[]	7	hSpCas9	negative selection	2721290
22128667	22128690	8	+	27260157	HT1080	viability	CACTAGGTAGGGTGGCAAGCAGG	HR	ENSG00000168453	-0.314479971098633	[]	[]	-7	hSpCas9	negative selection	2725333
22129031	22129054	8	+	27260157	MKN45	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.925909719038707	[]	[]	8	hSpCas9	negative selection	2727659
22129059	22129082	8	+	27260157	MKN45	viability	GGTGCAGTCCATCTCGAGGCGGG	HR	ENSG00000168453	1.32251288693241	[]	[]	9	hSpCas9	negative selection	2730005
22128867	22128890	8	-	27260157	MKN45	viability	AGAGGGACTGCGCTGGAAGGAGG	HR	ENSG00000168453	1.44101993896815	[]	[]	9	hSpCas9	negative selection	2730006
22127797	22127820	8	-	27260157	MKN45	viability	ACAAGGATCCGAGCATTCCCAGG	HR	ENSG00000168453	0.663275879385053	[]	[]	7	hSpCas9	negative selection	2730144
22129094	22129117	8	+	27260157	MKN45	viability	TGTCTCACGATGCCGTTCTCTGG	HR	ENSG00000168453	0.975601881141351	[]	[]	8	hSpCas9	negative selection	2730650
22129092	22129115	8	-	27260157	MKN45	viability	AGAGAACGGCATCGTGAGACAGG	HR	ENSG00000168453	0.933294510334064	[]	[]	8	hSpCas9	negative selection	2733438
22128830	22128853	8	+	27260157	MKN45	viability	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	0.769897256486204	[]	[]	7	hSpCas9	negative selection	2733887
22128846	22128869	8	-	27260157	MKN45	viability	GGCCATGCTTACCCATCCGCTGG	HR	ENSG00000168453	1.24230599509557	[]	[]	9	hSpCas9	negative selection	2736239
22127753	22127776	8	-	27260157	MKN45	viability	GCTGCGGAACCTGGGTTGTTTGG	HR	ENSG00000168453	0.288615825252888	[]	[]	5	hSpCas9	negative selection	2736503
22129085	22129108	8	-	27260157	MKN45	viability	GGCATCGTGAGACAGGAGCCCGG	HR	ENSG00000168453	-0.031976127064217	[]	[]	0	hSpCas9	negative selection	2736969
22128655	22128678	8	+	27260157	MKN45	viability	GGGCAGGCCAGACACTAGGTAGG	HR	ENSG00000168453	0.576778745373907	[]	[]	7	hSpCas9	negative selection	2756987
22128835	22128858	8	-	27260157	MKN45	viability	CCCATCCGCTGGCATTCTGCGGG	HR	ENSG00000168453	1.3185696180584	[]	[]	9	hSpCas9	negative selection	2759952
22129142	22129165	8	-	27260157	MKN45	viability	AGTACGCCCAGCTTCCTGAAGGG	HR	ENSG00000168453	1.68319533088691	[]	[]	9	hSpCas9	negative selection	2761515
22128812	22128835	8	+	27260157	MKN45	viability	CCACAGCGAGGTGGGCACGCTGG	HR	ENSG00000168453	-0.355052153995911	[]	[]	-1	hSpCas9	negative selection	2767014
22129054	22129077	8	-	27260157	MKN45	viability	CTCGAGATGGACTGCACCATGGG	HR	ENSG00000168453	2.09439996503422	[]	[]	9	hSpCas9	negative selection	2773679
22129066	22129089	8	+	27260157	MKN45	viability	TCCATCTCGAGGCGGGCTGCCGG	HR	ENSG00000168453	0.393237286518297	[]	[]	6	hSpCas9	negative selection	2775550
22129038	22129061	8	+	27260157	MKN45	viability	CTCCCAGGCACAGCGGCCCATGG	HR	ENSG00000168453	0.773869041117758	[]	[]	7	hSpCas9	negative selection	2793498
22128943	22128966	8	+	27260157	MKN45	viability	CACAAGTGGGAGCATGTCCTTGG	HR	ENSG00000168453	0.937888630563988	[]	[]	8	hSpCas9	negative selection	2797420
22128667	22128690	8	+	27260157	MKN45	viability	CACTAGGTAGGGTGGCAAGCAGG	HR	ENSG00000168453	0.566689012641928	[]	[]	7	hSpCas9	negative selection	2801463
22129031	22129054	8	+	27260157	RKO	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.555206322067816	[]	[]	-7	hSpCas9	negative selection	2803789
22129059	22129082	8	+	27260157	RKO	viability	GGTGCAGTCCATCTCGAGGCGGG	HR	ENSG00000168453	0.116346487105176	[]	[]	0	hSpCas9	negative selection	2806135
22128867	22128890	8	-	27260157	RKO	viability	AGAGGGACTGCGCTGGAAGGAGG	HR	ENSG00000168453	0.55678042430546	[]	[]	3	hSpCas9	negative selection	2806136
22127797	22127820	8	-	27260157	RKO	viability	ACAAGGATCCGAGCATTCCCAGG	HR	ENSG00000168453	1.14502179004127	[]	[]	9	hSpCas9	negative selection	2806274
22129094	22129117	8	+	27260157	RKO	viability	TGTCTCACGATGCCGTTCTCTGG	HR	ENSG00000168453	0.0956649714562876	[]	[]	0	hSpCas9	negative selection	2806780
22129092	22129115	8	-	27260157	RKO	viability	AGAGAACGGCATCGTGAGACAGG	HR	ENSG00000168453	0.972616708058616	[]	[]	8	hSpCas9	negative selection	2809568
22128830	22128853	8	+	27260157	RKO	viability	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	-0.349279879215466	[]	[]	-6	hSpCas9	negative selection	2810017
22128846	22128869	8	-	27260157	RKO	viability	GGCCATGCTTACCCATCCGCTGG	HR	ENSG00000168453	-0.00563087285307285	[]	[]	0	hSpCas9	negative selection	2812369
22127753	22127776	8	-	27260157	RKO	viability	GCTGCGGAACCTGGGTTGTTTGG	HR	ENSG00000168453	0.0593248486932504	[]	[]	0	hSpCas9	negative selection	2812633
22129085	22129108	8	-	27260157	RKO	viability	GGCATCGTGAGACAGGAGCCCGG	HR	ENSG00000168453	1.37151748664461	[]	[]	9	hSpCas9	negative selection	2813099
22128655	22128678	8	+	27260157	RKO	viability	GGGCAGGCCAGACACTAGGTAGG	HR	ENSG00000168453	-0.086804729118961	[]	[]	0	hSpCas9	negative selection	2833117
22128835	22128858	8	-	27260157	RKO	viability	CCCATCCGCTGGCATTCTGCGGG	HR	ENSG00000168453	0.146945488578021	[]	[]	0	hSpCas9	negative selection	2836082
22129142	22129165	8	-	27260157	RKO	viability	AGTACGCCCAGCTTCCTGAAGGG	HR	ENSG00000168453	0.842878163521906	[]	[]	8	hSpCas9	negative selection	2837645
22128812	22128835	8	+	27260157	RKO	viability	CCACAGCGAGGTGGGCACGCTGG	HR	ENSG00000168453	-0.154642070755726	[]	[]	0	hSpCas9	negative selection	2843144
22129054	22129077	8	-	27260157	RKO	viability	CTCGAGATGGACTGCACCATGGG	HR	ENSG00000168453	1.03300363028175	[]	[]	9	hSpCas9	negative selection	2849809
22129066	22129089	8	+	27260157	RKO	viability	TCCATCTCGAGGCGGGCTGCCGG	HR	ENSG00000168453	0.917786818031951	[]	[]	8	hSpCas9	negative selection	2851680
22129038	22129061	8	+	27260157	RKO	viability	CTCCCAGGCACAGCGGCCCATGG	HR	ENSG00000168453	0.0873891103178705	[]	[]	0	hSpCas9	negative selection	2869628
22128943	22128966	8	+	27260157	RKO	viability	CACAAGTGGGAGCATGTCCTTGG	HR	ENSG00000168453	0.709821379542568	[]	[]	8	hSpCas9	negative selection	2873550
22128667	22128690	8	+	27260157	RKO	viability	CACTAGGTAGGGTGGCAAGCAGG	HR	ENSG00000168453	-0.0578749930963726	[]	[]	0	hSpCas9	negative selection	2877593
22129031	22129054	8	+	27260157	SF268	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.0938116170951747	[]	[]	0	hSpCas9	negative selection	2879919
22129059	22129082	8	+	27260157	SF268	viability	GGTGCAGTCCATCTCGAGGCGGG	HR	ENSG00000168453	0.67560989925233	[]	[]	8	hSpCas9	negative selection	2882265
22128867	22128890	8	-	27260157	SF268	viability	AGAGGGACTGCGCTGGAAGGAGG	HR	ENSG00000168453	0.290392397064601	[]	[]	4	hSpCas9	negative selection	2882266
22127797	22127820	8	-	27260157	SF268	viability	ACAAGGATCCGAGCATTCCCAGG	HR	ENSG00000168453	1.0468823924634	[]	[]	9	hSpCas9	negative selection	2882404
22129094	22129117	8	+	27260157	SF268	viability	TGTCTCACGATGCCGTTCTCTGG	HR	ENSG00000168453	0.642863354941045	[]	[]	8	hSpCas9	negative selection	2882910
22129092	22129115	8	-	27260157	SF268	viability	AGAGAACGGCATCGTGAGACAGG	HR	ENSG00000168453	1.02924978452649	[]	[]	9	hSpCas9	negative selection	2885698
22128830	22128853	8	+	27260157	SF268	viability	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	0.136864456121943	[]	[]	0	hSpCas9	negative selection	2886147
22128846	22128869	8	-	27260157	SF268	viability	GGCCATGCTTACCCATCCGCTGG	HR	ENSG00000168453	0.789957186957161	[]	[]	8	hSpCas9	negative selection	2888499
22127753	22127776	8	-	27260157	SF268	viability	GCTGCGGAACCTGGGTTGTTTGG	HR	ENSG00000168453	-0.0791444019022935	[]	[]	0	hSpCas9	negative selection	2888763
22129085	22129108	8	-	27260157	SF268	viability	GGCATCGTGAGACAGGAGCCCGG	HR	ENSG00000168453	1.55999181204357	[]	[]	9	hSpCas9	negative selection	2889229
22128655	22128678	8	+	27260157	SF268	viability	GGGCAGGCCAGACACTAGGTAGG	HR	ENSG00000168453	-1.14521933704097	[]	[]	-7	hSpCas9	negative selection	2909247
22128835	22128858	8	-	27260157	SF268	viability	CCCATCCGCTGGCATTCTGCGGG	HR	ENSG00000168453	-0.0223965144840752	[]	[]	0	hSpCas9	negative selection	2912212
22129142	22129165	8	-	27260157	SF268	viability	AGTACGCCCAGCTTCCTGAAGGG	HR	ENSG00000168453	1.07371437025658	[]	[]	9	hSpCas9	negative selection	2913775
22128812	22128835	8	+	27260157	SF268	viability	CCACAGCGAGGTGGGCACGCTGG	HR	ENSG00000168453	-0.697881722666158	[]	[]	-5	hSpCas9	negative selection	2919274
22129054	22129077	8	-	27260157	SF268	viability	CTCGAGATGGACTGCACCATGGG	HR	ENSG00000168453	1.85486957459968	[]	[]	9	hSpCas9	negative selection	2925939
22129066	22129089	8	+	27260157	SF268	viability	TCCATCTCGAGGCGGGCTGCCGG	HR	ENSG00000168453	1.18132229088737	[]	[]	9	hSpCas9	negative selection	2927810
22129038	22129061	8	+	27260157	SF268	viability	CTCCCAGGCACAGCGGCCCATGG	HR	ENSG00000168453	0.977669367348955	[]	[]	9	hSpCas9	negative selection	2945758
22128943	22128966	8	+	27260157	SF268	viability	CACAAGTGGGAGCATGTCCTTGG	HR	ENSG00000168453	0.682189345963924	[]	[]	8	hSpCas9	negative selection	2949680
22128667	22128690	8	+	27260157	SF268	viability	CACTAGGTAGGGTGGCAAGCAGG	HR	ENSG00000168453	0.364011334819094	[]	[]	4	hSpCas9	negative selection	2953723
22127688	22127711	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACGCCCTTCACTGCACCAGAGGG	HR	ENSG00000168453	0.0331483700251996	[3,3]	[2,3]	0	hSpCas9	positive selection	2994122
22128732	22128755	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAAGGAAAGGGCAGTGCCAGGG	HR	ENSG00000168453	-0.5847719419354811	[2,2]	[0,1]	-7	hSpCas9	positive selection	2994123
22127255	22127278	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCAGTTTGAATGTCCACGCGG	HR	ENSG00000168453	-0.2386926373012077	[2,2]	[3,0]	-3	hSpCas9	positive selection	2994124
22128831	22128854	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	-1.5422390537847728	[2,2]	[0,0]	-9	hSpCas9	positive selection	2994125
22127688	22127711	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACGCCCTTCACTGCACCAGAGGG	HR	ENSG00000168453	0.057395229223451597	[3,3]	[4,0]	1	hSpCas9	positive selection	3061980
22128732	22128755	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAAGGAAAGGGCAGTGCCAGGG	HR	ENSG00000168453	0.3566393788492204	[2,2]	[3,2]	6	hSpCas9	positive selection	3061981
22127255	22127278	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCAGTTTGAATGTCCACGCGG	HR	ENSG00000168453	0.3810591862574723	[2,2]	[2,2]	6	hSpCas9	positive selection	3061982
22128831	22128854	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	-0.2134541126842459	[2,2]	[1,0]	-3	hSpCas9	positive selection	3061983
22125678	22125701		+	24336571	A375	resistance to PLX after 7 days	CATGGTATGTCCTGAAGTCCCGG	HR	ENSG00000168453	-0.1092435229631914	[28,30]	[28,25]	-3	hSpCas9	positive selection	3119748
22127203	22127226		-	24336571	A375	resistance to PLX after 7 days	CTCGGCTCCGGGCCCTCAAAAGG	HR	ENSG00000168453	0.14062546914699656	[9,11]	[12,10]	4	hSpCas9	positive selection	3119749
22125631	22125654		-	24336571	A375	resistance to PLX after 7 days	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.2504693733353698	[43,44]	[51,52]	7	hSpCas9	positive selection	3119750
22127701	22127724		+	24336571	A375	resistance to PLX after 7 days	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.04634952477639964	[29,28]	[28,30]	1	hSpCas9	positive selection	3119752
22125678	22125701		+	24336571	A375	resistance to PLX after 14 days	CATGGTATGTCCTGAAGTCCCGG	HR	ENSG00000168453	-0.8743901342458515	[24,30]	[5,6]	-8	hSpCas9	positive selection	3177541
22127203	22127226		-	24336571	A375	resistance to PLX after 14 days	CTCGGCTCCGGGCCCTCAAAAGG	HR	ENSG00000168453	-0.5275410538063015	[13,10]	[3,2]	-6	hSpCas9	positive selection	3177542
22125631	22125654		-	24336571	A375	resistance to PLX after 14 days	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.18430970881427	[45,46]	[21,26]	2	hSpCas9	positive selection	3177543
22127701	22127724		+	24336571	A375	resistance to PLX after 14 days	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.6190638383304945	[24,17]	[13,15]	5	hSpCas9	positive selection	3177545
22125678	22125701		+	24336571	A375	viability after 7 days	CATGGTATGTCCTGAAGTCCCGG	HR	ENSG00000168453	0.23237790247398082	[26]	[28,30]	3	hSpCas9	negative selection	3235334
22127203	22127226		-	24336571	A375	viability after 7 days	CTCGGCTCCGGGCCCTCAAAAGG	HR	ENSG00000168453	-0.3481661585786534	[14]	[9,11]	-5	hSpCas9	negative selection	3235335
22125631	22125654		-	24336571	A375	viability after 7 days	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.3930779023660511	[34]	[43,44]	6	hSpCas9	negative selection	3235336
22127701	22127724		+	24336571	A375	viability after 7 days	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.3213159224984591	[24]	[29,28]	5	hSpCas9	negative selection	3235338
22125678	22125701		+	24336571	A375	viability after 14 days	CATGGTATGTCCTGAAGTCCCGG	HR	ENSG00000168453	0.14961575714892994	[26]	[24,30]	2	hSpCas9	negative selection	3293127
22127203	22127226		-	24336571	A375	viability after 14 days	CTCGGCTCCGGGCCCTCAAAAGG	HR	ENSG00000168453	-0.14960643430441442	[14]	[13,10]	-2	hSpCas9	negative selection	3293128
22125631	22125654		-	24336571	A375	viability after 14 days	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.4740497713151379	[34]	[45,46]	6	hSpCas9	negative selection	3293129
22127701	22127724		+	24336571	A375	viability after 14 days	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	-0.09033014553524621	[24]	[24,17]	-1	hSpCas9	negative selection	3293131
22125348	22125371	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	-0.5122415788643914	[249,185]	[0,0]	-3	hSpCas9	positive selection	3354034
22127347	22127370	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.21378956316218667	[299,359]	[0,3]	1	hSpCas9	positive selection	3354035
22127701	22127724	8	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.10313686467907646	[132,151]	[0,0]	0	hSpCas9	positive selection	3354036
22125493	22125516	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	-0.631417037452424	[236,236]	[0,0]	-4	hSpCas9	positive selection	3373254
22125673	22125696	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-1.3313884241364287	[384,384]	[0,0]	-8	hSpCas9	positive selection	3373255
22125631	22125654	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.631417037452424	[236,236]	[0,0]	-4	hSpCas9	positive selection	3373256
22127688	22127711	8	-	26780180	HT29	viability (Avana library 4 designs)	ACGCCCTTCACTGCACCAGAGGG	HR	ENSG00000168453	1.2143895433037	[]	[]	5	hSpCas9	negative selection	3431416
22128731	22128754	8	+	26780180	HT29	viability (Avana library 4 designs)	AGAAGGAAAGGGCAGTGCCAGGG	HR	ENSG00000168453	2.64484515462307	[]	[]	8	hSpCas9	negative selection	3431417
22127255	22127278	8	-	26780180	HT29	viability (Avana library 4 designs)	GAGCAGTTTGAATGTCCACGCGG	HR	ENSG00000168453	-0.0306328010766334	[]	[]	0	hSpCas9	negative selection	3431418
22128830	22128853	8	+	26780180	HT29	viability (Avana library 4 designs)	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	0.866419830707927	[]	[]	3	hSpCas9	negative selection	3431419
22127255	22127278	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCAGTTTGAATGTCCACGCGG	HR	ENSG00000168453	6.09634299029706	[]	[]	9	hSpCas9	negative selection	3517054
22127688	22127711	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACGCCCTTCACTGCACCAGAGGG	HR	ENSG00000168453	-4.99988388744141	[]	[]	-5	hSpCas9	negative selection	3517055
22128830	22128853	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	3.58761327674777	[]	[]	6	hSpCas9	negative selection	3517056
22128731	22128754	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAAGGAAAGGGCAGTGCCAGGG	HR	ENSG00000168453	3.02591601034197	[]	[]	4	hSpCas9	negative selection	3517057
22129031	22129054	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	3.59279728394435	[]	[]	6	hSpCas9	negative selection	3517058
22127240	22127263	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCGACCTCAGGGCAGCCGCGTGG	HR	ENSG00000168453	5.46347424632021	[]	[]	8	hSpCas9	negative selection	3517059
22127255	22127278	8	-	26780180	A375	viability (Avana lentiGuide)	GAGCAGTTTGAATGTCCACGCGG	HR	ENSG00000168453	1.87186111904206	[]	[]	2	hSpCas9	negative selection	3625713
22127688	22127711	8	-	26780180	A375	viability (Avana lentiGuide)	ACGCCCTTCACTGCACCAGAGGG	HR	ENSG00000168453	-4.18066438828793	[]	[]	-7	hSpCas9	negative selection	3625714
22128830	22128853	8	+	26780180	A375	viability (Avana lentiGuide)	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	-7.32317470006819	[]	[]	-9	hSpCas9	negative selection	3625715
22128731	22128754	8	+	26780180	A375	viability (Avana lentiGuide)	AGAAGGAAAGGGCAGTGCCAGGG	HR	ENSG00000168453	5.92540118182241	[]	[]	5	hSpCas9	negative selection	3625716
22129031	22129054	8	+	26780180	A375	viability (Avana lentiGuide)	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.385628784550583	[]	[]	0	hSpCas9	negative selection	3625717
22127240	22127263	8	+	26780180	A375	viability (Avana lentiGuide)	TCGACCTCAGGGCAGCCGCGTGG	HR	ENSG00000168453	0.950779928653756	[]	[]	1	hSpCas9	negative selection	3625718
22127255	22127278	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCAGTTTGAATGTCCACGCGG	HR	ENSG00000168453	0.2632226661634297	[4]	[5,5]	7	hSpCas9	positive selection	3734372
22127688	22127711	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACGCCCTTCACTGCACCAGAGGG	HR	ENSG00000168453	-0.07251178503478115	[4]	[5,3]	-1	hSpCas9	positive selection	3734373
22128830	22128853	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	0.27893395936050647	[4]	[5,5]	7	hSpCas9	positive selection	3734374
22128731	22128754	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAAGGAAAGGGCAGTGCCAGGG	HR	ENSG00000168453	0.23266402552507437	[4]	[4,5]	6	hSpCas9	positive selection	3734375
22129031	22129054	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.24097173382347298	[4]	[5,4]	7	hSpCas9	positive selection	3734376
22127240	22127263	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCGACCTCAGGGCAGCCGCGTGG	HR	ENSG00000168453	0.27353745971088084	[4]	[6,5]	7	hSpCas9	positive selection	3734377
22127255	22127278	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCAGTTTGAATGTCCACGCGG	HR	ENSG00000168453	0.023133069402370053	[5]	[3,4]	0	hSpCas9	positive selection	3842979
22127688	22127711	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACGCCCTTCACTGCACCAGAGGG	HR	ENSG00000168453	-0.1738914047902155	[5]	[3,4]	-2	hSpCas9	positive selection	3842980
22128830	22128853	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGCCCGCAGAATGCCAGCGG	HR	ENSG00000168453	0.126806025861459	[4]	[2,4]	3	hSpCas9	positive selection	3842981
22128731	22128754	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAAGGAAAGGGCAGTGCCAGGG	HR	ENSG00000168453	-0.5688462272100406	[3]	[1,1]	-6	hSpCas9	positive selection	3842982
22129031	22129054	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.0326575415386791	[5]	[4,3]	0	hSpCas9	positive selection	3842983
22127240	22127263	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCGACCTCAGGGCAGCCGCGTGG	HR	ENSG00000168453	0.17333055308284465	[6]	[6,5]	4	hSpCas9	positive selection	3842984
22125348	22125371	8	-	26780180	A375	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	1.08476444374075	[]	[]	5	hSpCas9	negative selection	3949036
22125673	22125696	8	-	26780180	A375	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	1.24296367231155	[]	[]	6	hSpCas9	negative selection	3949037
22125493	22125516	8	-	26780180	A375	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	1.18284621385699	[]	[]	6	hSpCas9	negative selection	3949038
22127347	22127370	8	+	26780180	A375	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	1.07289051321553	[]	[]	5	hSpCas9	negative selection	3949039
22125631	22125654	8	-	26780180	A375	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	1.64872331862355	[]	[]	8	hSpCas9	negative selection	3949040
22127701	22127724	8	+	26780180	A375	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	1.78792381468695	[]	[]	9	hSpCas9	negative selection	3949041
22125348	22125371	8	-	26780180	HT29	viability (GeCKOv2 library)	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.723071655124693	[]	[]	2	hSpCas9	negative selection	4057002
22125673	22125696	8	-	26780180	HT29	viability (GeCKOv2 library)	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.429910129355268	[]	[]	1	hSpCas9	negative selection	4057003
22125493	22125516	8	-	26780180	HT29	viability (GeCKOv2 library)	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.736804660039158	[]	[]	3	hSpCas9	negative selection	4057004
22127347	22127370	8	+	26780180	HT29	viability (GeCKOv2 library)	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.766925536910148	[]	[]	3	hSpCas9	negative selection	4057005
22125631	22125654	8	-	26780180	HT29	viability (GeCKOv2 library)	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	1.63959448185452	[]	[]	8	hSpCas9	negative selection	4057006
22127701	22127724	8	+	26780180	HT29	viability (GeCKOv2 library)	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	2.04294735263889	[]	[]	9	hSpCas9	negative selection	4057007
22125678	22125701	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATGGTATGTCCTGAAGTCCCGG	HR	ENSG00000168453	-0.08800159261467852	[4]	[2,2]	-2	hSpCas9	positive selection	4143302
22127203	22127226	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGGCTCCGGGCCCTCAAAAGG	HR	ENSG00000168453	-0.15283104565585626	[4]	[2,1]	-4	hSpCas9	positive selection	4143303
22125631	22125654	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.19168085646840854	[5]	[3,4]	5	hSpCas9	positive selection	4143304
22127701	22127724	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.3040032563845606	[4]	[3,3]	7	hSpCas9	positive selection	4143306
22125678	22125701	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATGGTATGTCCTGAAGTCCCGG	HR	ENSG00000168453	0.9949384774150809	[4]	[3,3,1,4]	7	hSpCas9	positive selection	4207324
22127203	22127226	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGGCTCCGGGCCCTCAAAAGG	HR	ENSG00000168453	0.26946194508621585	[3]	[4,3,1,0]	2	hSpCas9	positive selection	4207325
22125631	22125654	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	1.0109922639189897	[4]	[4,4,3,3]	7	hSpCas9	positive selection	4207326
22127701	22127724	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	1.2782312042905917	[3]	[4,1,2,5]	9	hSpCas9	positive selection	4207328
22125348	22125371	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.4982638225800956	[3]	[3,3]	8	hSpCas9	positive selection	4275749
22127347	22127370	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.05976348098670364	[3]	[3,2]	1	hSpCas9	positive selection	4275750
22127701	22127724	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.17427888733623484	[2]	[2,2]	3	hSpCas9	positive selection	4275751
22125493	22125516	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.28307192666199427	[2]	[3,2]	6	hSpCas9	positive selection	4340009
22125673	22125696	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.3176375932038937	[4]	[4,3]	6	hSpCas9	positive selection	4340010
22125631	22125654	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.17620320467317407	[3]	[2,3]	3	hSpCas9	positive selection	4340011
22127077	22127099	8	-	27760321	OCIAML3	viability	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	-0.5047377210562041	[385,278]	[167,198]	-5	hSpCas9	negative selection	4407960
22127741	22127763	8	-	27760321	OCIAML3	viability	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-1.0113354314406413	[315,304]	[88,161]	-7	hSpCas9	negative selection	4407961
22128598	22128620	8	+	27760321	OCIAML3	viability	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	0.5283249627547019	[372,278]	[341,393]	6	hSpCas9	negative selection	4407962
22128836	22128858	8	+	27760321	OCIAML3	viability	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	-0.07667183357982699	[379,331]	[252,276]	-1	hSpCas9	negative selection	4407963
22129008	22129030	8	+	27760321	OCIAML3	viability	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.603861746002819	[274,211]	[229,361]	7	hSpCas9	negative selection	4407964
22127077	22127099	8	-	27760321	OCIAML2	viability	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	-0.4491150470063785	[385,278]	[163,235]	-5	hSpCas9	negative selection	4491423
22127741	22127763	8	-	27760321	OCIAML2	viability	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.5344925509192731	[315,304]	[149,204]	-5	hSpCas9	negative selection	4491424
22128598	22128620	8	+	27760321	OCIAML2	viability	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	-0.1756808384186201	[372,278]	[180,297]	-2	hSpCas9	negative selection	4491425
22128836	22128858	8	+	27760321	OCIAML2	viability	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	-0.8364933254826106	[379,331]	[131,198]	-7	hSpCas9	negative selection	4491426
22129008	22129030	8	+	27760321	OCIAML2	viability	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.5519560733618367	[274,211]	[271,305]	7	hSpCas9	negative selection	4491427
22127077	22127099	8	-	27760321	MV411	viability	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	-2.19099763262303	[385,278]	[17,91]	-8	hSpCas9	negative selection	4574886
22127741	22127763	8	-	27760321	MV411	viability	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.77455785856463	[315,304]	[115,125]	-5	hSpCas9	negative selection	4574887
22128598	22128620	8	+	27760321	MV411	viability	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	-0.25209655544539317	[372,278]	[49,372]	-2	hSpCas9	negative selection	4574888
22128836	22128858	8	+	27760321	MV411	viability	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	-0.17189399269917482	[379,331]	[289,84]	-1	hSpCas9	negative selection	4574889
22129008	22129030	8	+	27760321	MV411	viability	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	-1.6631805928309562	[274,211]	[5,116]	-8	hSpCas9	negative selection	4574890
22127077	22127099	8	-	27760321	HL60	viability	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.32202248525531324	[385,278]	[291,382]	4	hSpCas9	negative selection	4658349
22127741	22127763	8	-	27760321	HL60	viability	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	0.18591844972556187	[315,304]	[323,251]	2	hSpCas9	negative selection	4658350
22128598	22128620	8	+	27760321	HL60	viability	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	-0.11156864596900046	[372,278]	[173,318]	-1	hSpCas9	negative selection	4658351
22128836	22128858	8	+	27760321	HL60	viability	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.2425855871649144	[379,331]	[418,262]	3	hSpCas9	negative selection	4658352
22129008	22129030	8	+	27760321	HL60	viability	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.6550341801506692	[274,211]	[390,225]	7	hSpCas9	negative selection	4658353
22127077	22127099	8	-	27760321	HT1080	viability	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	1.1393959990300626	[278,217]	[219,215]	6	hSpCas9	negative selection	4741812
22127741	22127763	8	-	27760321	HT1080	viability	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	1.0003299812758102	[304,237]	[223,207]	5	hSpCas9	negative selection	4741813
22128598	22128620	8	+	27760321	HT1080	viability	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	0.11151539236258967	[278,217]	[84,130]	0	hSpCas9	negative selection	4741814
22128836	22128858	8	+	27760321	HT1080	viability	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	-0.5659273271658793	[331,258]	[100,55]	-3	hSpCas9	negative selection	4741815
22129008	22129030	8	+	27760321	HT1080	viability	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	1.0746204168925044	[211,165]	[181,132]	6	hSpCas9	negative selection	4741816
22127077	22127099	8	-	27760321	HT29	viability after 7 days	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.18502698961996733	[278,217]	[428,255,411]	3	hSpCas9	negative selection	4825275
22127741	22127763	8	-	27760321	HT29	viability after 7 days	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.31791512838098324	[304,237]	[261,195,375]	-4	hSpCas9	negative selection	4825276
22128598	22128620	8	+	27760321	HT29	viability after 7 days	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	0.44381647298218085	[278,217]	[333,460,491]	6	hSpCas9	negative selection	4825277
22128836	22128858	8	+	27760321	HT29	viability after 7 days	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.33258438210491326	[331,258]	[470,340,616]	5	hSpCas9	negative selection	4825278
22129008	22129030	8	+	27760321	HT29	viability after 7 days	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.6407011609536044	[211,165]	[568,235,358]	8	hSpCas9	negative selection	4825279
22127077	22127099	8	-	27760321	HT29	viability after 25 days	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.7539683384720064	[278,217]	[640,365,411]	8	hSpCas9	negative selection	4908738
22127741	22127763	8	-	27760321	HT29	viability after 25 days	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.15402428526543577	[304,237]	[171,321,356]	-1	hSpCas9	negative selection	4908739
22128598	22128620	8	+	27760321	HT29	viability after 25 days	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	0.7001039780552174	[278,217]	[404,486,498]	7	hSpCas9	negative selection	4908740
22128836	22128858	8	+	27760321	HT29	viability after 25 days	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.8328478332962557	[331,258]	[484,585,755]	8	hSpCas9	negative selection	4908741
22129008	22129030	8	+	27760321	HT29	viability after 25 days	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.7833003136346385	[211,165]	[240,338,562]	8	hSpCas9	negative selection	4908742
22127077	22127099	8	-	27760321	HT29	viability after 22 days	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.5885011443624726	[278,217]	[480,347,465]	6	hSpCas9	negative selection	4992201
22127741	22127763	8	-	27760321	HT29	viability after 22 days	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.08483557523612967	[304,237]	[523,128,227]	-1	hSpCas9	negative selection	4992202
22128598	22128620	8	+	27760321	HT29	viability after 22 days	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	1.321966995174284	[278,217]	[719,582,852]	9	hSpCas9	negative selection	4992203
22128836	22128858	8	+	27760321	HT29	viability after 22 days	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.7621317999008597	[331,258]	[680,610,441]	8	hSpCas9	negative selection	4992204
22129008	22129030	8	+	27760321	HT29	viability after 22 days	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.7397809304843299	[211,165]	[424,426,239]	8	hSpCas9	negative selection	4992205
22127077	22127099	8	-	27760321	HT29	viability after 19 days	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.518894399134546	[278,217]	[528,425,283]	5	hSpCas9	negative selection	5075664
22127741	22127763	8	-	27760321	HT29	viability after 19 days	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-1.68559899380872	[304,237]	[158,38,97]	-7	hSpCas9	negative selection	5075665
22128598	22128620	8	+	27760321	HT29	viability after 19 days	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	0.7705012869506426	[278,217]	[523,467,466]	7	hSpCas9	negative selection	5075666
22128836	22128858	8	+	27760321	HT29	viability after 19 days	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.7694332606171252	[331,258]	[762,451,533]	7	hSpCas9	negative selection	5075667
22129008	22129030	8	+	27760321	HT29	viability after 19 days	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.5749507941254912	[211,165]	[300,427,237]	6	hSpCas9	negative selection	5075668
22127077	22127099	8	-	27760321	HT29	viability after 16 days	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.4001913729437503	[278,217]	[509,222,384]	4	hSpCas9	negative selection	5159127
22127741	22127763	8	-	27760321	HT29	viability after 16 days	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.2706369008129508	[304,237]	[240,340,169]	-3	hSpCas9	negative selection	5159128
22128598	22128620	8	+	27760321	HT29	viability after 16 days	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	0.8347817612888465	[278,217]	[465,412,607]	8	hSpCas9	negative selection	5159129
22128836	22128858	8	+	27760321	HT29	viability after 16 days	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.6775501722708488	[331,258]	[501,439,643]	7	hSpCas9	negative selection	5159130
22129008	22129030	8	+	27760321	HT29	viability after 16 days	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.9650359882238565	[211,165]	[534,223,495]	9	hSpCas9	negative selection	5159131
22127077	22127099	8	-	27760321	HT29	viability after 13 days	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.4428492765324109	[278,217]	[449,461,270]	5	hSpCas9	negative selection	5242590
22127741	22127763	8	-	27760321	HT29	viability after 13 days	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.6688560436798823	[304,237]	[303,107,182]	-6	hSpCas9	negative selection	5242591
22128598	22128620	8	+	27760321	HT29	viability after 13 days	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	1.003643524178699	[278,217]	[577,473,675]	9	hSpCas9	negative selection	5242592
22128836	22128858	8	+	27760321	HT29	viability after 13 days	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.8047459436341899	[331,258]	[413,906,482]	9	hSpCas9	negative selection	5242593
22129008	22129030	8	+	27760321	HT29	viability after 13 days	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	1.1760807427620603	[211,165]	[448,513,521]	9	hSpCas9	negative selection	5242594
22127077	22127099	8	-	27760321	HT29	viability after 10 days	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	0.21514360402932448	[278,217]	[525,335,220]	3	hSpCas9	negative selection	5326053
22127741	22127763	8	-	27760321	HT29	viability after 10 days	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-0.6972012963317415	[304,237]	[307,60,252]	-7	hSpCas9	negative selection	5326054
22128598	22128620	8	+	27760321	HT29	viability after 10 days	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	1.0709958565042603	[278,217]	[555,603,790]	9	hSpCas9	negative selection	5326055
22128836	22128858	8	+	27760321	HT29	viability after 10 days	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	0.3137760985347856	[331,258]	[289,500,582]	4	hSpCas9	negative selection	5326056
22129008	22129030	8	+	27760321	HT29	viability after 10 days	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	0.6522736933782166	[211,165]	[268,420,422]	8	hSpCas9	negative selection	5326057
22127077	22127099	8	-	27760321	MOLM13	viability	GGTGCGGGACACATCGATAGGG	HR	ENSG00000168453	-0.5855559025408384	[385,278]	[220,40]	-4	hSpCas9	negative selection	5409516
22127741	22127763	8	-	27760321	MOLM13	viability	GGTTGTTTGGCTTAAACTCTGG	HR	ENSG00000168453	-1.0789168750921247	[315,304]	[81,83]	-6	hSpCas9	negative selection	5409517
22128598	22128620	8	+	27760321	MOLM13	viability	GCCCCCGGAGTATACCCAGGGG	HR	ENSG00000168453	0.9094155584414509	[372,278]	[227,439]	6	hSpCas9	negative selection	5409518
22128836	22128858	8	+	27760321	MOLM13	viability	CCGCAGAATGCCAGCGGATGGG	HR	ENSG00000168453	-0.2666220836069702	[379,331]	[77,241]	-2	hSpCas9	negative selection	5409519
22129008	22129030	8	+	27760321	MOLM13	viability	TCAGGACGCCCCTCCAAAAGGG	HR	ENSG00000168453	-1.939146711852185	[274,211]	[27,41]	-8	hSpCas9	negative selection	5409520
22130587	22130610	8	+	27661255	K562	viability	GGGGCGGCGGGGGCGCTCTAGGG	HR	ENSG00000168453	0.04243662863735409	[344,443]	[355,294]	1	dCas9-KRAB	negative selection	5485496
22130598	22130621	8	+	27661255	K562	viability	GGCGCTCTAGGGCCGCAGGTTGG	HR	ENSG00000168453	0.24696046673261063	[514,526]	[558,437]	8	dCas9-KRAB	negative selection	5485497
22130928	22130951	8	+	27661255	K562	viability	GCACCGCGCAGCGCGGCTAATGG	HR	ENSG00000168453	0.27436461587513294	[554,557]	[603,480]	8	dCas9-KRAB	negative selection	5485498
22132992	22133015	8	+	27661255	K562	viability	GGCTGTTCTGTGCCTGAAGACGG	HR	ENSG00000168453	0.12709714471600575	[703,640]	[686,502]	4	dCas9-KRAB	negative selection	5485499
22133353	22133376	8	+	27661255	K562	viability	GGCCAAGCTGCCACTAATCCGGG	HR	ENSG00000168453	0.18972499664281262	[417,688]	[535,468]	6	dCas9-KRAB	negative selection	5485500
22132972	22132995	8	-	27661255	K562	viability	GCCGGCTACAAGGACTCTGTGGG	HR	ENSG00000168453	-0.11283253857132136	[180,186]	[137,133]	-4	dCas9-KRAB	negative selection	5485501
22133342	22133365	8	-	27661255	K562	viability	GGCAGCTTGGCCTGACTCTCCGG	HR	ENSG00000168453	0.015687787815519882	[644,719]	[589,515]	0	dCas9-KRAB	negative selection	5485502
22125348	22125371	8	-	27260156	BXPC3	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.4612364741546019	[556]	[807,656,787,977]	8	hSpCas9	negative selection	5548209
22127347	22127370	8	+	27260156	BXPC3	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.2672060348769003	[953]	[1229,1052,1150,1386]	6	hSpCas9	negative selection	5548210
22127701	22127724	8	+	27260156	BXPC3	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.4581353584028988	[412]	[509,630,463,792]	8	hSpCas9	negative selection	5548211
22125493	22125516	8	-	27260156	BXPC3	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.48842043273051927	[392]	[442,528,574,799]	9	hSpCas9	negative selection	5612469
22125673	22125696	8	-	27260156	BXPC3	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.029128775184280586	[1015]	[1076,975,1104,1190]	0	hSpCas9	negative selection	5612470
22125631	22125654	8	-	27260156	BXPC3	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.12372056583410185	[844]	[813,680,830,934]	-3	hSpCas9	negative selection	5612471
22125348	22125371	8	-	27260156	A673	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.30155495212118844	[556]	[970,857,703,776]	7	hSpCas9	negative selection	5669460
22127347	22127370	8	+	27260156	A673	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.3777723798651973	[953]	[1552,1322,1601,1482]	8	hSpCas9	negative selection	5669461
22127701	22127724	8	+	27260156	A673	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.33939420588955416	[412]	[768,579,487,693]	7	hSpCas9	negative selection	5669462
22125493	22125516	8	-	27260156	A673	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.5871779809429432	[392]	[701,743,645,742]	9	hSpCas9	negative selection	5733720
22125673	22125696	8	-	27260156	A673	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.09033053694325655	[1015]	[1458,1130,1210,1421]	2	hSpCas9	negative selection	5733721
22125631	22125654	8	-	27260156	A673	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.023957689183011888	[844]	[1172,867,1138,959]	0	hSpCas9	negative selection	5733722
22125348	22125371	8	-	27260156	A375	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.23799061343800304	[556]	[563,757,1054,694]	3	hSpCas9	negative selection	5790711
22127347	22127370	8	+	27260156	A375	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.4000076459631645	[953]	[1375,1738,1667,1165]	6	hSpCas9	negative selection	5790712
22127701	22127724	8	+	27260156	A375	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.16014801139857213	[412]	[586,690,566,352]	2	hSpCas9	negative selection	5790713
22125493	22125516	8	-	27260156	A375	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.5604592071594771	[392]	[618,694,963,455]	8	hSpCas9	negative selection	5854971
22125673	22125696	8	-	27260156	A375	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.03785447542450893	[1015]	[1324,1291,1106,1161]	0	hSpCas9	negative selection	5854972
22125631	22125654	8	-	27260156	A375	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.16957054730518983	[844]	[964,1216,1169,1098]	2	hSpCas9	negative selection	5854973
22125348	22125371	8	-	27260156	COLO741	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.22533847182894629	[556]	[923,874,711]	5	hSpCas9	negative selection	5911962
22127347	22127370	8	+	27260156	COLO741	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.19422134343812525	[953]	[1585,1501,1128]	4	hSpCas9	negative selection	5911963
22127701	22127724	8	+	27260156	COLO741	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.109589211961015	[412]	[661,574,483]	2	hSpCas9	negative selection	5911964
22125493	22125516	8	-	27260156	COLO741	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.7717662816089494	[392]	[810,1019,743]	9	hSpCas9	negative selection	5976222
22125673	22125696	8	-	27260156	COLO741	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.082257873436828	[1015]	[1133,1262,1267]	-2	hSpCas9	negative selection	5976223
22125631	22125654	8	-	27260156	COLO741	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.0358284171207931	[844]	[1207,936,1026]	0	hSpCas9	negative selection	5976224
22125348	22125371	8	-	27260156	CAL120	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.5528941934867533	[556]	[925,1126,983]	7	hSpCas9	negative selection	6033213
22127347	22127370	8	+	27260156	CAL120	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.4867559306872056	[953]	[1915,1453,1657]	7	hSpCas9	negative selection	6033214
22127701	22127724	8	+	27260156	CAL120	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.30665556123946575	[412]	[740,459,719]	4	hSpCas9	negative selection	6033215
22125493	22125516	8	-	27260156	CAL120	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.33645081157434437	[392]	[782,581,513]	5	hSpCas9	negative selection	6097473
22125673	22125696	8	-	27260156	CAL120	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.3047107986590327	[1015]	[1918,1760,1066]	4	hSpCas9	negative selection	6097474
22125631	22125654	8	-	27260156	CAL120	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.26163552339633434	[844]	[1193,683,801]	-4	hSpCas9	negative selection	6097475
22125348	22125371	8	-	27260156	CADOES1	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	-0.002792364763607086	[556]	[655,473,515,417]	0	hSpCas9	negative selection	6154464
22127347	22127370	8	+	27260156	CADOES1	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.4729028924046166	[953]	[1203,1085,1340,1296]	7	hSpCas9	negative selection	6154465
22127701	22127724	8	+	27260156	CADOES1	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.4992217606333886	[412]	[480,406,524,766]	7	hSpCas9	negative selection	6154466
22125493	22125516	8	-	27260156	CADOES1	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.361421454869455	[392]	[375,441,601,457]	6	hSpCas9	negative selection	6218724
22125673	22125696	8	-	27260156	CADOES1	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.00019621676249181874	[1015]	[892,878,839,1176]	0	hSpCas9	negative selection	6218725
22125631	22125654	8	-	27260156	CADOES1	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.09488386603886811	[844]	[875,662,489,920]	-2	hSpCas9	negative selection	6218726
22125348	22125371	8	-	27260156	EWS502	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.30964573301539455	[556]	[545,934,659,798]	5	hSpCas9	negative selection	6275715
22127347	22127370	8	+	27260156	EWS502	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.45371602144707346	[953]	[1309,1287,1539,1408]	7	hSpCas9	negative selection	6275716
22127701	22127724	8	+	27260156	EWS502	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.10608968034066295	[412]	[344,594,541,405]	1	hSpCas9	negative selection	6275717
22125493	22125516	8	-	27260156	EWS502	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.789355805009275	[392]	[681,718,646,838]	9	hSpCas9	negative selection	6339975
22125673	22125696	8	-	27260156	EWS502	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.009267260697532143	[1015]	[1046,1051,1071,1107]	0	hSpCas9	negative selection	6339976
22125631	22125654	8	-	27260156	EWS502	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.04509725314996782	[844]	[923,810,823,904]	-1	hSpCas9	negative selection	6339977
22125348	22125371	8	-	27260156	EW8	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.27385156545692946	[556]	[662,549,459,535]	5	hSpCas9	negative selection	6396966
22127347	22127370	8	+	27260156	EW8	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.3712632444107462	[953]	[1237,985,813,1016]	6	hSpCas9	negative selection	6396967
22127701	22127724	8	+	27260156	EW8	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.5221953709061723	[412]	[731,571,326,344]	8	hSpCas9	negative selection	6396968
22125493	22125516	8	-	27260156	EW8	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.5799582420655487	[392]	[429,506,451,512]	8	hSpCas9	negative selection	6461226
22125673	22125696	8	-	27260156	EW8	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.22395373813990016	[1015]	[1122,837,787,1140]	4	hSpCas9	negative selection	6461227
22125631	22125654	8	-	27260156	EW8	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.19617609584231066	[844]	[872,981,672,637]	3	hSpCas9	negative selection	6461228
22125348	22125371	8	-	27260156	CORL105	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.3080984894988267	[556]	[893,770,801,764]	6	hSpCas9	negative selection	6518217
22127347	22127370	8	+	27260156	CORL105	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.2312423024487127	[953]	[1285,1201,1390,1377]	4	hSpCas9	negative selection	6518218
22127701	22127724	8	+	27260156	CORL105	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.376037710602898	[412]	[476,518,692,826]	7	hSpCas9	negative selection	6518219
22125493	22125516	8	-	27260156	CORL105	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.47655392147241826	[392]	[623,479,850,640]	8	hSpCas9	negative selection	6582477
22125673	22125696	8	-	27260156	CORL105	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.09225908681066719	[1015]	[1270,811,1251,1159]	-2	hSpCas9	negative selection	6582478
22125631	22125654	8	-	27260156	CORL105	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.21496000454626096	[844]	[1031,1129,1503,978]	4	hSpCas9	negative selection	6582479
22125348	22125371	8	-	27260156	HS294T	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.5460493951881716	[556]	[304,200,453,298]	7	hSpCas9	negative selection	6639468
22127347	22127370	8	+	27260156	HS294T	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.3070911972597439	[953]	[349,554,423,510]	4	hSpCas9	negative selection	6639469
22127701	22127724	8	+	27260156	HS294T	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.019202252472798803	[412]	[142,150,132,233]	0	hSpCas9	negative selection	6639470
22125493	22125516	8	-	27260156	HS294T	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.9146141654252873	[392]	[338,245,184,387]	9	hSpCas9	negative selection	6703728
22125673	22125696	8	-	27260156	HS294T	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.09734416169735405	[1015]	[255,286,411,557]	-1	hSpCas9	negative selection	6703729
22125631	22125654	8	-	27260156	HS294T	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.5628760592057087	[844]	[439,413,280,863]	7	hSpCas9	negative selection	6703730
22125348	22125371	8	-	27260156	HCC44	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.045102281462753524	[556]	[632,491,843,678]	0	hSpCas9	negative selection	6760719
22127347	22127370	8	+	27260156	HCC44	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.4761524018428718	[953]	[1857,968,1952,1400]	7	hSpCas9	negative selection	6760720
22127701	22127724	8	+	27260156	HCC44	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.4397662778102531	[412]	[536,847,538,551]	7	hSpCas9	negative selection	6760721
22125493	22125516	8	-	27260156	HCC44	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.7106622443144817	[392]	[999,509,853,620]	9	hSpCas9	negative selection	6824979
22125673	22125696	8	-	27260156	HCC44	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.13501093536941888	[1015]	[1267,821,1635,1432]	2	hSpCas9	negative selection	6824980
22125631	22125654	8	-	27260156	HCC44	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.10360182436114751	[844]	[1012,1269,1017,768]	1	hSpCas9	negative selection	6824981
22125348	22125371	8	-	27260156	G402	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.5445944044164109	[556]	[996,708,825,1393]	6	hSpCas9	negative selection	6881970
22127347	22127370	8	+	27260156	G402	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.6151032656851616	[953]	[2177,1640,1449,1898]	7	hSpCas9	negative selection	6881971
22127701	22127724	8	+	27260156	G402	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.12521933213946532	[412]	[591,376,514,700]	1	hSpCas9	negative selection	6881972
22125493	22125516	8	-	27260156	G402	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.33912078978001564	[392]	[742,638,654,417]	4	hSpCas9	negative selection	6946230
22125673	22125696	8	-	27260156	G402	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.3614424590326756	[1015]	[1081,1122,854,828]	-4	hSpCas9	negative selection	6946231
22125631	22125654	8	-	27260156	G402	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.09574196558787529	[844]	[1659,1321,912,624]	1	hSpCas9	negative selection	6946232
22125348	22125371	8	-	27260156	L33	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.3038060709586681	[556]	[615,248,467,782]	6	hSpCas9	negative selection	7003221
22127347	22127370	8	+	27260156	L33	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.31900997839748446	[953]	[1292,487,785,1024]	6	hSpCas9	negative selection	7003222
22127701	22127724	8	+	27260156	L33	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.47698688652616605	[412]	[695,239,315,511]	8	hSpCas9	negative selection	7003223
22125493	22125516	8	-	27260156	L33	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.43618109949733436	[392]	[441,200,368,608]	8	hSpCas9	negative selection	7067481
22125673	22125696	8	-	27260156	L33	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.19173480607758397	[1015]	[863,373,647,752]	-4	hSpCas9	negative selection	7067482
22125631	22125654	8	-	27260156	L33	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.06198315003518662	[844]	[867,314,543,734]	-1	hSpCas9	negative selection	7067483
22125348	22125371	8	-	27260156	K562	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.3734624392098175	[556]	[570,1235,445,363]	5	hSpCas9	negative selection	7124472
22127347	22127370	8	+	27260156	K562	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.42911191748150124	[953]	[1036,1093,1887,589]	5	hSpCas9	negative selection	7124473
22127701	22127724	8	+	27260156	K562	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.6689139768381266	[412]	[1037,409,386,527]	8	hSpCas9	negative selection	7124474
22125493	22125516	8	-	27260156	K562	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.8850362271189258	[392]	[959,463,700,483]	9	hSpCas9	negative selection	7188732
22125673	22125696	8	-	27260156	K562	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.34044704293554884	[1015]	[1342,1484,814,972]	4	hSpCas9	negative selection	7188733
22125631	22125654	8	-	27260156	K562	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.08564021140146616	[844]	[941,708,607,596]	-1	hSpCas9	negative selection	7188734
22125348	22125371	8	-	27260156	HT29	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.47874456864542714	[556]	[915,1001,834,1008]	8	hSpCas9	negative selection	7245723
22127347	22127370	8	+	27260156	HT29	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.309309771932073	[953]	[1545,1725,1342,1186]	6	hSpCas9	negative selection	7245724
22127701	22127724	8	+	27260156	HT29	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.3261934428546391	[412]	[700,704,542,581]	6	hSpCas9	negative selection	7245725
22125493	22125516	8	-	27260156	HT29	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.4200537454503991	[392]	[761,645,710,464]	7	hSpCas9	negative selection	7309983
22125673	22125696	8	-	27260156	HT29	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.014162775498359315	[1015]	[1225,1190,1450,1035]	0	hSpCas9	negative selection	7309984
22125631	22125654	8	-	27260156	HT29	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.03552900883645549	[844]	[1241,1011,1144,841]	0	hSpCas9	negative selection	7309985
22125348	22125371	8	-	27260156	MHHES1	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.08673618765356328	[556]	[808,807,344,706]	1	hSpCas9	negative selection	7366974
22127347	22127370	8	+	27260156	MHHES1	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.4188286623547264	[953]	[1859,1218,1660,1085]	7	hSpCas9	negative selection	7366975
22127701	22127724	8	+	27260156	MHHES1	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.29330674602078655	[412]	[612,496,707,470]	5	hSpCas9	negative selection	7366976
22125493	22125516	8	-	27260156	MHHES1	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.6992602915903359	[392]	[535,610,922,748]	9	hSpCas9	negative selection	7431234
22125673	22125696	8	-	27260156	MHHES1	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.043241106088028	[1015]	[1291,1302,1184,981]	0	hSpCas9	negative selection	7431235
22125631	22125654	8	-	27260156	MHHES1	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.010070419012652265	[844]	[1006,1171,860,785]	0	hSpCas9	negative selection	7431236
22125348	22125371	8	-	27260156	MEWO	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.448795097612641	[556]	[916,604,651]	8	hSpCas9	negative selection	7488225
22127347	22127370	8	+	27260156	MEWO	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.344225720254967	[953]	[1411,906,1134]	7	hSpCas9	negative selection	7488226
22127701	22127724	8	+	27260156	MEWO	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.2909169690434405	[412]	[542,400,487]	6	hSpCas9	negative selection	7488227
22125493	22125516	8	-	27260156	MEWO	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.4503908327450678	[392]	[717,470,359]	8	hSpCas9	negative selection	7552485
22125673	22125696	8	-	27260156	MEWO	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.1419144782902826	[1015]	[1265,1090,830]	3	hSpCas9	negative selection	7552486
22125631	22125654	8	-	27260156	MEWO	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.040191633364776935	[844]	[909,665,881]	0	hSpCas9	negative selection	7552487
22125348	22125371	8	-	27260156	LNCAPCLONEFGC	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.21227430942563869	[556]	[490,497,878,520]	3	hSpCas9	negative selection	7609476
22127347	22127370	8	+	27260156	LNCAPCLONEFGC	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.6171605552313659	[953]	[1442,922,1752,1269]	8	hSpCas9	negative selection	7609477
22127701	22127724	8	+	27260156	LNCAPCLONEFGC	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.2949943843736872	[412]	[422,374,573,486]	4	hSpCas9	negative selection	7609478
22125493	22125516	8	-	27260156	LNCAPCLONEFGC	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.7222986790515649	[392]	[633,538,477,683]	9	hSpCas9	negative selection	7673736
22125673	22125696	8	-	27260156	LNCAPCLONEFGC	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.23063301777472545	[1015]	[801,644,872,838]	-4	hSpCas9	negative selection	7673737
22125631	22125654	8	-	27260156	LNCAPCLONEFGC	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.207402782842655	[844]	[760,916,844,1005]	3	hSpCas9	negative selection	7673738
22125348	22125371	8	-	27260156	PANC0327	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	-0.10114413249423929	[556]	[748,349,435,347]	-1	hSpCas9	negative selection	7730727
22127347	22127370	8	+	27260156	PANC0327	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.687205699707262	[953]	[1381,1140,1440,1523]	8	hSpCas9	negative selection	7730728
22127701	22127724	8	+	27260156	PANC0327	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.762607978715234	[412]	[899,445,599,588]	9	hSpCas9	negative selection	7730729
22125493	22125516	8	-	27260156	PANC0327	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.4449651728296945	[392]	[378,510,374,622]	6	hSpCas9	negative selection	7794987
22125673	22125696	8	-	27260156	PANC0327	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.23030050979595607	[1015]	[1105,819,999,1342]	3	hSpCas9	negative selection	7794988
22125631	22125654	8	-	27260156	PANC0327	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.23263234678642553	[844]	[925,635,972,1027]	3	hSpCas9	negative selection	7794989
22125348	22125371	8	-	27260156	NCIH2009	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.7796486511361636	[556]	[1988,1265,880]	9	hSpCas9	negative selection	7851978
22127347	22127370	8	+	27260156	NCIH2009	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.6776315008052154	[953]	[2303,2147,1973]	8	hSpCas9	negative selection	7851979
22127701	22127724	8	+	27260156	NCIH2009	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.6718697062845314	[412]	[1178,787,842]	8	hSpCas9	negative selection	7851980
22125493	22125516	8	-	27260156	NCIH2009	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.7293783637070883	[392]	[1322,801,687]	8	hSpCas9	negative selection	7916238
22125673	22125696	8	-	27260156	NCIH2009	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.15741958006175372	[1015]	[1963,1532,1325]	2	hSpCas9	negative selection	7916239
22125631	22125654	8	-	27260156	NCIH2009	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.32756117825011755	[844]	[2019,1507,1019]	4	hSpCas9	negative selection	7916240
22125348	22125371	8	-	27260156	NCIH1373	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	-0.09885960409417066	[556]	[792,489,549,140]	-1	hSpCas9	negative selection	7973229
22127347	22127370	8	+	27260156	NCIH1373	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.6015813098653033	[953]	[1764,1529,1289,513]	6	hSpCas9	negative selection	7973230
22127701	22127724	8	+	27260156	NCIH1373	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	1.0634499189256421	[412]	[633,1356,881,234]	9	hSpCas9	negative selection	7973231
22125493	22125516	8	-	27260156	NCIH1373	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.9374730306692045	[392]	[793,984,672,236]	8	hSpCas9	negative selection	8037489
22125673	22125696	8	-	27260156	NCIH1373	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.0154213936065557	[1015]	[1297,1175,1221,237]	0	hSpCas9	negative selection	8037490
22125631	22125654	8	-	27260156	NCIH1373	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.5134915135166218	[844]	[1187,1512,1127,405]	5	hSpCas9	negative selection	8037491
22125348	22125371	8	-	27260156	PATU8902	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.8253833796400865	[556]	[1732,1129,859,1962]	8	hSpCas9	negative selection	8094480
22127347	22127370	8	+	27260156	PATU8902	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.6686715625294475	[953]	[2336,2619,1435,2225]	7	hSpCas9	negative selection	8094481
22127701	22127724	8	+	27260156	PATU8902	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	1.0457849083368442	[412]	[1081,981,1240,1453]	9	hSpCas9	negative selection	8094482
22125493	22125516	8	-	27260156	PATU8902	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.8720976311272681	[392]	[931,1385,898,784]	8	hSpCas9	negative selection	8158740
22125673	22125696	8	-	27260156	PATU8902	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.1671842775682535	[1015]	[1125,1438,1582,2284]	1	hSpCas9	negative selection	8158741
22125631	22125654	8	-	27260156	PATU8902	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.640848031794	[844]	[2022,2111,1616,1599]	6	hSpCas9	negative selection	8158742
22125348	22125371	8	-	27260156	PANC1	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.5492705790463234	[556]	[791,830,510,680]	8	hSpCas9	negative selection	8215731
22127347	22127370	8	+	27260156	PANC1	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.13017249482696958	[953]	[746,1014,888,940]	2	hSpCas9	negative selection	8215732
22127701	22127724	8	+	27260156	PANC1	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.132366120321457	[412]	[427,441,318,371]	2	hSpCas9	negative selection	8215733
22125493	22125516	8	-	27260156	PANC1	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.5318833888654652	[392]	[436,619,362,541]	8	hSpCas9	negative selection	8279991
22125673	22125696	8	-	27260156	PANC1	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.024427641472045902	[1015]	[865,1192,812,648]	0	hSpCas9	negative selection	8279992
22125631	22125654	8	-	27260156	PANC1	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.07040847870456313	[844]	[603,1012,855,638]	1	hSpCas9	negative selection	8279993
22125348	22125371	8	-	27260156	PANC0813	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.8810858809444306	[556]	[1802,1003,1068,1007]	9	hSpCas9	negative selection	8336982
22127347	22127370	8	+	27260156	PANC0813	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.38982096148678447	[953]	[1483,1540,1814,1056]	6	hSpCas9	negative selection	8336983
22127701	22127724	8	+	27260156	PANC0813	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.6128395618938183	[412]	[780,621,766,796]	8	hSpCas9	negative selection	8336984
22125493	22125516	8	-	27260156	PANC0813	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.8240423599606739	[392]	[1020,832,776,663]	9	hSpCas9	negative selection	8401242
22125673	22125696	8	-	27260156	PANC0813	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.2589597763715701	[1015]	[1155,1577,1708,1252]	4	hSpCas9	negative selection	8401243
22125631	22125654	8	-	27260156	PANC0813	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.018383604258123798	[844]	[1007,934,914,1152]	0	hSpCas9	negative selection	8401244
22125348	22125371	8	-	27260156	RDES	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	-0.050771769530794375	[556]	[448,595,766,700]	-1	hSpCas9	negative selection	8458233
22127347	22127370	8	+	27260156	RDES	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.44401803620884084	[953]	[1424,1186,1559,1850]	7	hSpCas9	negative selection	8458234
22127701	22127724	8	+	27260156	RDES	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.5092602305387104	[412]	[501,706,699,834]	7	hSpCas9	negative selection	8458235
22125493	22125516	8	-	27260156	RDES	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.49617787907603494	[392]	[545,593,754,667]	7	hSpCas9	negative selection	8522493
22125673	22125696	8	-	27260156	RDES	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.009045502605795841	[1015]	[950,1023,1126,1637]	0	hSpCas9	negative selection	8522494
22125631	22125654	8	-	27260156	RDES	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.03441890496199829	[844]	[810,886,1191,1140]	0	hSpCas9	negative selection	8522495
22125348	22125371	8	-	27260156	PC3	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.11622969678396966	[556]	[356,744,923,545]	2	hSpCas9	negative selection	8579484
22127347	22127370	8	+	27260156	PC3	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.2981288480612192	[953]	[750,1171,1832,1248]	6	hSpCas9	negative selection	8579485
22127701	22127724	8	+	27260156	PC3	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.17360390225622246	[412]	[254,362,712,690]	4	hSpCas9	negative selection	8579486
22125493	22125516	8	-	27260156	PC3	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.7102549088990273	[392]	[543,542,1186,460]	9	hSpCas9	negative selection	8643744
22125673	22125696	8	-	27260156	PC3	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.18482282123849858	[1015]	[724,1000,2322,1093]	4	hSpCas9	negative selection	8643745
22125631	22125654	8	-	27260156	PC3	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.03328213648819056	[844]	[457,630,1607,1009]	0	hSpCas9	negative selection	8643746
22125348	22125371	8	-	27260156	PATU8988T	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.453820631774288	[556]	[607,747,805,790]	7	hSpCas9	negative selection	8700735
22127347	22127370	8	+	27260156	PATU8988T	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.49106314133412066	[953]	[1245,1328,1247,1368]	7	hSpCas9	negative selection	8700736
22127701	22127724	8	+	27260156	PATU8988T	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.1546621679886665	[412]	[419,657,327,387]	2	hSpCas9	negative selection	8700737
22125493	22125516	8	-	27260156	PATU8988T	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.7798915717044692	[392]	[846,623,325,826]	9	hSpCas9	negative selection	8764995
22125673	22125696	8	-	27260156	PATU8988T	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.12241500508041425	[1015]	[975,897,1265,1119]	2	hSpCas9	negative selection	8764996
22125631	22125654	8	-	27260156	PATU8988T	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.0034692287044726378	[844]	[869,894,890,606]	0	hSpCas9	negative selection	8764997
22125348	22125371	8	-	27260156	T47D	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.5026178561577436	[556]	[944,833,935,970]	9	hSpCas9	negative selection	8821986
22127347	22127370	8	+	27260156	T47D	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.5387708724104765	[953]	[1654,1344,1729,1753]	9	hSpCas9	negative selection	8821987
22127701	22127724	8	+	27260156	T47D	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.3808209955423585	[412]	[596,640,641,623]	7	hSpCas9	negative selection	8821988
22125493	22125516	8	-	27260156	T47D	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.5635796360427008	[392]	[656,670,648,731]	9	hSpCas9	negative selection	8886246
22125673	22125696	8	-	27260156	T47D	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.14638752019636447	[1015]	[1245,1247,1352,1399]	3	hSpCas9	negative selection	8886247
22125631	22125654	8	-	27260156	T47D	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.02440188970125723	[844]	[1023,916,945,989]	0	hSpCas9	negative selection	8886248
22125348	22125371	8	-	27260156	SU8686	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.627729004579559	[556]	[773,833,929,887]	9	hSpCas9	negative selection	8943237
22127347	22127370	8	+	27260156	SU8686	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.5202546138685344	[953]	[1266,1391,1281,1501]	8	hSpCas9	negative selection	8943238
22127701	22127724	8	+	27260156	SU8686	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.4290856046634107	[412]	[502,348,656,760]	7	hSpCas9	negative selection	8943239
22125493	22125516	8	-	27260156	SU8686	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.735970166747607	[392]	[699,617,591,682]	9	hSpCas9	negative selection	9007497
22125673	22125696	8	-	27260156	SU8686	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.11073910221892325	[1015]	[972,879,828,1062]	-2	hSpCas9	negative selection	9007498
22125631	22125654	8	-	27260156	SU8686	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.1369232679896667	[844]	[596,848,648,987]	-2	hSpCas9	negative selection	9007499
22125348	22125371	8	-	27260156	SKES1	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.2125165572755467	[556]	[836,580,587,588]	4	hSpCas9	negative selection	9064488
22127347	22127370	8	+	27260156	SKES1	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.29496016651752144	[953]	[1235,1072,1099,1238]	6	hSpCas9	negative selection	9064489
22127701	22127724	8	+	27260156	SKES1	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.45217471414311816	[412]	[476,547,597,605]	8	hSpCas9	negative selection	9064490
22125493	22125516	8	-	27260156	SKES1	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.5980682593230934	[392]	[508,650,615,586]	9	hSpCas9	negative selection	9128748
22125673	22125696	8	-	27260156	SKES1	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.07111127072536272	[1015]	[1135,988,852,905]	-1	hSpCas9	negative selection	9128749
22125631	22125654	8	-	27260156	SKES1	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.13222713034807165	[844]	[1036,831,646,616]	-3	hSpCas9	negative selection	9128750
22125348	22125371	8	-	27260156	TOV112D	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	-0.08206044268370902	[556]	[500,640,461,528]	-1	hSpCas9	negative selection	9185739
22127347	22127370	8	+	27260156	TOV112D	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.1665865984535655	[953]	[1231,1223,966,919]	3	hSpCas9	negative selection	9185740
22127701	22127724	8	+	27260156	TOV112D	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.10120509806590818	[412]	[403,524,427,433]	2	hSpCas9	negative selection	9185741
22125493	22125516	8	-	27260156	TOV112D	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.5986012273029291	[392]	[756,350,836,396]	9	hSpCas9	negative selection	9249999
22125673	22125696	8	-	27260156	TOV112D	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.024669688296244496	[1015]	[1215,1414,816,805]	0	hSpCas9	negative selection	9250000
22125631	22125654	8	-	27260156	TOV112D	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.4067075074785509	[844]	[943,1786,1125,786]	7	hSpCas9	negative selection	9250001
22125348	22125371	8	-	27260156	TC71	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	0.3781162996161924	[556]	[843,678,806,770]	8	hSpCas9	negative selection	9306990
22127347	22127370	8	+	27260156	TC71	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.3725885751945677	[953]	[1314,1292,1319,1370]	8	hSpCas9	negative selection	9306991
22127701	22127724	8	+	27260156	TC71	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.4053736856124186	[412]	[528,493,630,697]	8	hSpCas9	negative selection	9306992
22125493	22125516	8	-	27260156	TC71	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.6248939825931756	[392]	[594,720,616,668]	9	hSpCas9	negative selection	9371250
22125673	22125696	8	-	27260156	TC71	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	0.11206527347732687	[1015]	[1074,1255,1157,1224]	3	hSpCas9	negative selection	9371251
22125631	22125654	8	-	27260156	TC71	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	-0.20317820573257905	[844]	[749,855,715,830]	-5	hSpCas9	negative selection	9371252
22125348	22125371	8	-	27260156	TC32	viability	ACCGACTGTGCCGCCTGCTGCGG	HR	ENSG00000168453	-0.011078653924575854	[556]	[349,491,578,675]	0	hSpCas9	negative selection	9428241
22127347	22127370	8	+	27260156	TC32	viability	GGCCTTGTTCACTTCCTCGCTGG	HR	ENSG00000168453	0.5827972691724466	[953]	[1356,1028,1746,1342]	8	hSpCas9	negative selection	9428242
22127701	22127724	8	+	27260156	TC32	viability	TGAAGGGCGTTCGGCCTCCCCGG	HR	ENSG00000168453	0.5367031452247458	[412]	[523,343,682,790]	8	hSpCas9	negative selection	9428243
22125493	22125516	8	-	27260156	TC32	viability	CCTCTCTCCAGATCGCCTCTGGG	HR	ENSG00000168453	0.20388400400229206	[392]	[305,251,738,522]	3	hSpCas9	negative selection	9492501
22125673	22125696	8	-	27260156	TC32	viability	ACTTCAGGACATACCATGCCTGG	HR	ENSG00000168453	-0.25926602303077984	[1015]	[590,757,967,900]	-5	hSpCas9	negative selection	9492502
22125631	22125654	8	-	27260156	TC32	viability	TCAATGCCAAAGTTGTGCCCAGG	HR	ENSG00000168453	0.08592817559007238	[844]	[764,682,926,1040]	1	hSpCas9	negative selection	9492503
22122550	22122573	8	-	27869803	HPAFII	viability after 27 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	0.6146148643567295	[61]	[62,38,NaN]	5	hSpCas9	negative selection	9602089
22123780	22123803	8	-	27869803	HPAFII	viability after 27 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.3741346366851648	[318]	[509,371,NaN]	9	hSpCas9	negative selection	9602090
22125403	22125426	8	-	27869803	HPAFII	viability after 27 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-1.5249317503218034	[103]	[0,33,NaN]	-7	hSpCas9	negative selection	9602091
22125581	22125604	8	-	27869803	HPAFII	viability after 27 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.6506472123167248	[135]	[50,40,NaN]	-5	hSpCas9	negative selection	9602092
22127435	22127458	8	-	27869803	HPAFII	viability after 27 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.4339572850430316	[380]	[192,110,NaN]	-3	hSpCas9	negative selection	9602093
22129058	22129081	8	+	27869803	HPAFII	viability after 27 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.2631331199242173	[474]	[428,23,NaN]	-2	hSpCas9	negative selection	9602094
22122550	22122573	8	-	27869803	HPAFII	viability after 15 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	0.62362034245074	[61]	[77,117,NaN]	7	hSpCas9	negative selection	9684538
22123780	22123803	8	-	27869803	HPAFII	viability after 15 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.8928900822364887	[318]	[791,539,NaN]	8	hSpCas9	negative selection	9684539
22125403	22125426	8	-	27869803	HPAFII	viability after 15 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.18741828962210172	[103]	[64,165,NaN]	2	hSpCas9	negative selection	9684540
22125581	22125604	8	-	27869803	HPAFII	viability after 15 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.24285218758476812	[135]	[270,111,NaN]	2	hSpCas9	negative selection	9684541
22127435	22127458	8	-	27869803	HPAFII	viability after 15 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.07549643474458378	[380]	[514,309,NaN]	-1	hSpCas9	negative selection	9684542
22129058	22129081	8	+	27869803	HPAFII	viability after 15 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	-0.15745606771536302	[474]	[950,150,NaN]	-2	hSpCas9	negative selection	9684543
22122550	22122573	8	-	27869803	ASPC1	viability after 36 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.007641635705405658	[179]	[138,0,56]	0	hSpCas9	negative selection	9766987
22123780	22123803	8	-	27869803	ASPC1	viability after 36 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	-0.5589442862671364	[859]	[202,300,124]	-5	hSpCas9	negative selection	9766988
22125403	22125426	8	-	27869803	ASPC1	viability after 36 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	1.4112843194822178	[188]	[427,68,80]	9	hSpCas9	negative selection	9766989
22125581	22125604	8	-	27869803	ASPC1	viability after 36 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.9255982846803279	[459]	[32,111,97]	-7	hSpCas9	negative selection	9766990
22127435	22127458	8	-	27869803	ASPC1	viability after 36 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.10859192618320745	[1023]	[574,182,408]	1	hSpCas9	negative selection	9766991
22129058	22129081	8	+	27869803	ASPC1	viability after 36 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.017715072167162393	[1172]	[272,598,362]	0	hSpCas9	negative selection	9766992
22122550	22122573	8	-	27869803	PATU8988S	viability after 35 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.1330145693078486	[131]	[39,56,NaN]	-1	hSpCas9	negative selection	9849436
22123780	22123803	8	-	27869803	PATU8988S	viability after 35 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.999847571540598	[775]	[844,403,NaN]	8	hSpCas9	negative selection	9849437
22125403	22125426	8	-	27869803	PATU8988S	viability after 35 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.7096813559272639	[258]	[212,127,NaN]	7	hSpCas9	negative selection	9849438
22125581	22125604	8	-	27869803	PATU8988S	viability after 35 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.25131049285145013	[383]	[99,159,NaN]	-3	hSpCas9	negative selection	9849439
22127435	22127458	8	-	27869803	PATU8988S	viability after 35 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	0.29896224557354945	[901]	[415,477,NaN]	3	hSpCas9	negative selection	9849440
22129058	22129081	8	+	27869803	PATU8988S	viability after 35 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.5902015348704219	[761]	[469,453,NaN]	6	hSpCas9	negative selection	9849441
22122550	22122573	8	-	27869803	PATU8988S	viability after 31 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	0.004365601878903114	[131]	[21,91,NaN]	0	hSpCas9	negative selection	9931885
22123780	22123803	8	-	27869803	PATU8988S	viability after 31 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	0.7840181294881129	[775]	[556,501,NaN]	8	hSpCas9	negative selection	9931886
22125403	22125426	8	-	27869803	PATU8988S	viability after 31 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	0.7703539257368711	[258]	[147,211,NaN]	8	hSpCas9	negative selection	9931887
22125581	22125604	8	-	27869803	PATU8988S	viability after 31 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.5137911141803729	[383]	[108,104,NaN]	-5	hSpCas9	negative selection	9931888
22127435	22127458	8	-	27869803	PATU8988S	viability after 31 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.06023457288032985	[901]	[340,349,NaN]	0	hSpCas9	negative selection	9931889
22129058	22129081	8	+	27869803	PATU8988S	viability after 31 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.33123334675861954	[761]	[288,500,NaN]	4	hSpCas9	negative selection	9931890
22122550	22122573	8	-	27869803	HPAFII	viability after 35 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.29778288250322316	[61]	[33,15,NaN]	-2	hSpCas9	negative selection	10014334
22123780	22123803	8	-	27869803	HPAFII	viability after 35 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.250944637453587	[318]	[373,395,NaN]	8	hSpCas9	negative selection	10014335
22125403	22125426	8	-	27869803	HPAFII	viability after 35 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-2.8875635486216904	[103]	[0,13,NaN]	-8	hSpCas9	negative selection	10014336
22125581	22125604	8	-	27869803	HPAFII	viability after 35 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.3696209530469112	[135]	[41,65,NaN]	-2	hSpCas9	negative selection	10014337
22127435	22127458	8	-	27869803	HPAFII	viability after 35 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.41023448234412496	[380]	[194,88,NaN]	-3	hSpCas9	negative selection	10014338
22129058	22129081	8	+	27869803	HPAFII	viability after 35 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.39788816536173766	[474]	[575,24,NaN]	2	hSpCas9	negative selection	10014339
22122550	22122573	8	-	27869803	HPAFII	viability after 31 days	GGGTCAAGTTTGATATCCGGGGG	HR	ENSG00000168453	-0.14223721337697004	[61]	[20,42,NaN]	-1	hSpCas9	negative selection	10096783
22123780	22123803	8	-	27869803	HPAFII	viability after 31 days	GCCGTGACAGAGGACAGCCCAGG	HR	ENSG00000168453	1.3336731965984143	[318]	[433,469,NaN]	8	hSpCas9	negative selection	10096784
22125403	22125426	8	-	27869803	HPAFII	viability after 31 days	CCTGACAGCCGGCTCAGCACAGG	HR	ENSG00000168453	-2.75317755193785	[103]	[0,16,NaN]	-8	hSpCas9	negative selection	10096785
22125581	22125604	8	-	27869803	HPAFII	viability after 31 days	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.2308750691693532	[135]	[79,99,NaN]	1	hSpCas9	negative selection	10096786
22127435	22127458	8	-	27869803	HPAFII	viability after 31 days	TCCTACCCACCCACTAAAGGTGG	HR	ENSG00000168453	-0.33385836799445	[380]	[239,92,NaN]	-2	hSpCas9	negative selection	10096787
22129058	22129081	8	+	27869803	HPAFII	viability after 31 days	TGGTGCAGTCCATCTCGAGGCGG	HR	ENSG00000168453	0.06611504001373703	[474]	[492,45,NaN]	0	hSpCas9	negative selection	10096788
22128874	22128897	8	-	28162770	P31FUJ	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.34118917848577424	[87]	[130]	4	hSpCas9	negative selection	10171080
22127454	22127477	8	+	28162770	P31FUJ	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.07753791619777194	[224]	[278]	0	hSpCas9	negative selection	10171081
22127394	22127417	8	-	28162770	P31FUJ	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-2.5371362392870025	[162]	[32]	-8	hSpCas9	negative selection	10171082
22125581	22125604	8	-	28162770	P31FUJ	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.2652246595354968	[227]	[321]	3	hSpCas9	negative selection	10171083
22129143	22129166	8	-	28162770	P31FUJ	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	-0.21582912581066516	[168]	[170]	-2	hSpCas9	negative selection	10171084
22129031	22129054	8	+	28162770	P31FUJ	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.34770429922718105	[208]	[192]	-3	hSpCas9	negative selection	10171085
22128939	22128962	8	-	28162770	P31FUJ	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-0.32180721047312355	[116]	[109]	-3	hSpCas9	negative selection	10171086
22128812	22128835	8	-	28162770	P31FUJ	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.6970099473455373	[178]	[340]	7	hSpCas9	negative selection	10171087
22128600	22128623	8	-	28162770	P31FUJ	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.11757439403817704	[444]	[481]	-1	hSpCas9	negative selection	10171088
22127521	22127544	8	-	28162770	P31FUJ	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-0.6341647667961456	[69]	[52]	-5	hSpCas9	negative selection	10171089
22128874	22128897	8	-	28162770	TF1	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10340446
22127454	22127477	8	+	28162770	TF1	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	NaN	[NaN]	[284]	1	hSpCas9	negative selection	10340447
22127394	22127417	8	-	28162770	TF1	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	NaN	[NaN]	[4]	1	hSpCas9	negative selection	10340448
22125581	22125604	8	-	28162770	TF1	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	NaN	[NaN]	[186]	1	hSpCas9	negative selection	10340449
22129143	22129166	8	-	28162770	TF1	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10340450
22129031	22129054	8	+	28162770	TF1	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10340451
22128939	22128962	8	-	28162770	TF1	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10340452
22128812	22128835	8	-	28162770	TF1	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10340453
22128600	22128623	8	-	28162770	TF1	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10340454
22127521	22127544	8	-	28162770	TF1	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	NaN	[NaN]	[100]	1	hSpCas9	negative selection	10340455
22128874	22128897	8	-	28162770	SKM1	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.4658578877967301	[24]	[31]	-4	hSpCas9	negative selection	10509812
22127454	22127477	8	+	28162770	SKM1	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.6705967845504911	[42]	[120]	6	hSpCas9	negative selection	10509813
22127394	22127417	8	-	28162770	SKM1	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.6776117886868307	[37]	[20]	-8	hSpCas9	negative selection	10509814
22125581	22125604	8	-	28162770	SKM1	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.4768427837523157	[62]	[154]	4	hSpCas9	negative selection	10509815
22129143	22129166	8	-	28162770	SKM1	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	-0.25810081282867897	[45]	[67]	-2	hSpCas9	negative selection	10509816
22129031	22129054	8	+	28162770	SKM1	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.26191386593987864	[77]	[114]	-2	hSpCas9	negative selection	10509817
22128939	22128962	8	-	28162770	SKM1	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-1.132341818634156	[30]	[24]	-7	hSpCas9	negative selection	10509818
22128812	22128835	8	-	28162770	SKM1	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.4498029174395205	[40]	[98]	4	hSpCas9	negative selection	10509819
22128600	22128623	8	-	28162770	SKM1	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	0.5429951187572428	[98]	[254]	5	hSpCas9	negative selection	10509820
22127521	22127544	8	-	28162770	SKM1	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	0.4846596402120462	[18]	[46]	5	hSpCas9	negative selection	10509821
22128874	22128897	8	-	28162770	SKM1	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.4658578877967301	[24]	[31]	-4	hSpCas9	negative selection	10679178
22127454	22127477	8	+	28162770	SKM1	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.6705967845504911	[42]	[120]	6	hSpCas9	negative selection	10679179
22127394	22127417	8	-	28162770	SKM1	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.6776117886868307	[37]	[20]	-8	hSpCas9	negative selection	10679180
22125581	22125604	8	-	28162770	SKM1	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.4768427837523157	[62]	[154]	4	hSpCas9	negative selection	10679181
22129143	22129166	8	-	28162770	SKM1	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	-0.25810081282867897	[45]	[67]	-2	hSpCas9	negative selection	10679182
22129031	22129054	8	+	28162770	SKM1	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.26191386593987864	[77]	[114]	-2	hSpCas9	negative selection	10679183
22128939	22128962	8	-	28162770	SKM1	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-1.132341818634156	[30]	[24]	-7	hSpCas9	negative selection	10679184
22128812	22128835	8	-	28162770	SKM1	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.4498029174395205	[40]	[98]	4	hSpCas9	negative selection	10679185
22128600	22128623	8	-	28162770	SKM1	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	0.5429951187572428	[98]	[254]	5	hSpCas9	negative selection	10679186
22127521	22127544	8	-	28162770	SKM1	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	0.4846596402120462	[18]	[46]	5	hSpCas9	negative selection	10679187
22128874	22128897	8	-	28162770	PL21	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.022252806847127715	[125]	[53]	0	hSpCas9	negative selection	10848544
22127454	22127477	8	+	28162770	PL21	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	-0.032223095602055885	[241]	[102]	0	hSpCas9	negative selection	10848545
22127394	22127417	8	-	28162770	PL21	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-2.86163658309737	[166]	[9]	-9	hSpCas9	negative selection	10848546
22125581	22125604	8	-	28162770	PL21	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.2684133941165255	[237]	[85]	-2	hSpCas9	negative selection	10848547
22129143	22129166	8	-	28162770	PL21	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.3875097503910419	[136]	[77]	3	hSpCas9	negative selection	10848548
22129031	22129054	8	+	28162770	PL21	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.0411029291897439	[296]	[132]	0	hSpCas9	negative selection	10848549
22128939	22128962	8	-	28162770	PL21	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	0.08466239706938405	[77]	[35]	0	hSpCas9	negative selection	10848550
22128812	22128835	8	-	28162770	PL21	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	-0.42044679596255763	[122]	[39]	-3	hSpCas9	negative selection	10848551
22128600	22128623	8	-	28162770	PL21	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	0.6341602171357367	[301]	[203]	5	hSpCas9	negative selection	10848552
22127521	22127544	8	-	28162770	PL21	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	0.6475985914605414	[65]	[44]	5	hSpCas9	negative selection	10848553
22128874	22128897	8	-	28162770	P31FUJ	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.34118917848577424	[87]	[130]	4	hSpCas9	negative selection	11017910
22127454	22127477	8	+	28162770	P31FUJ	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.07753791619777194	[224]	[278]	0	hSpCas9	negative selection	11017911
22127394	22127417	8	-	28162770	P31FUJ	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-2.5371362392870025	[162]	[32]	-8	hSpCas9	negative selection	11017912
22125581	22125604	8	-	28162770	P31FUJ	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.2652246595354968	[227]	[321]	3	hSpCas9	negative selection	11017913
22129143	22129166	8	-	28162770	P31FUJ	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	-0.21582912581066516	[168]	[170]	-2	hSpCas9	negative selection	11017914
22129031	22129054	8	+	28162770	P31FUJ	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.34770429922718105	[208]	[192]	-3	hSpCas9	negative selection	11017915
22128939	22128962	8	-	28162770	P31FUJ	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-0.32180721047312355	[116]	[109]	-3	hSpCas9	negative selection	11017916
22128812	22128835	8	-	28162770	P31FUJ	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.6970099473455373	[178]	[340]	7	hSpCas9	negative selection	11017917
22128600	22128623	8	-	28162770	P31FUJ	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.11757439403817704	[444]	[481]	-1	hSpCas9	negative selection	11017918
22127521	22127544	8	-	28162770	P31FUJ	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-0.6341647667961456	[69]	[52]	-5	hSpCas9	negative selection	11017919
22128874	22128897	8	-	28162770	OCIAML5	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.3135194948539781	[36]	[82]	2	hSpCas9	negative selection	11187276
22127454	22127477	8	+	28162770	OCIAML5	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.455831964119307	[123]	[306]	4	hSpCas9	negative selection	11187277
22127394	22127417	8	-	28162770	OCIAML5	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-2.548674427414062	[93]	[28]	-8	hSpCas9	negative selection	11187278
22125581	22125604	8	-	28162770	OCIAML5	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.5516556151870124	[95]	[253]	5	hSpCas9	negative selection	11187279
22129143	22129166	8	-	28162770	OCIAML5	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.4374400463309879	[98]	[241]	4	hSpCas9	negative selection	11187280
22129031	22129054	8	+	28162770	OCIAML5	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-1.5467744775684962	[156]	[96]	-7	hSpCas9	negative selection	11187281
22128939	22128962	8	-	28162770	OCIAML5	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-0.1237398949716636	[66]	[110]	-1	hSpCas9	negative selection	11187282
22128812	22128835	8	-	28162770	OCIAML5	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.43033315983672793	[73]	[179]	3	hSpCas9	negative selection	11187283
22128600	22128623	8	-	28162770	OCIAML5	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.2390896939732441	[237]	[363]	-2	hSpCas9	negative selection	11187284
22127521	22127544	8	-	28162770	OCIAML5	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-1.125085065270413	[28]	[23]	-6	hSpCas9	negative selection	11187285
22128874	22128897	8	-	28162770	EOL1	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.04570488503541337	[191]	[97]	0	hSpCas9	negative selection	11356642
22127454	22127477	8	+	28162770	EOL1	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	-0.06893892147079117	[220]	[110]	0	hSpCas9	negative selection	11356643
22127394	22127417	8	-	28162770	EOL1	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.982342824037984	[209]	[27]	-8	hSpCas9	negative selection	11356644
22125581	22125604	8	-	28162770	EOL1	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.3506870878687862	[379]	[156]	-3	hSpCas9	negative selection	11356645
22129143	22129166	8	-	28162770	EOL1	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.04080084006638279	[285]	[154]	0	hSpCas9	negative selection	11356646
22129031	22129054	8	+	28162770	EOL1	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	0.21039206031241442	[501]	[305]	2	hSpCas9	negative selection	11356647
22128939	22128962	8	-	28162770	EOL1	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	0.5517385076809882	[100]	[77]	5	hSpCas9	negative selection	11356648
22128812	22128835	8	-	28162770	EOL1	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.8720803516763991	[167]	[161]	7	hSpCas9	negative selection	11356649
22128600	22128623	8	-	28162770	EOL1	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	0.4832135285834635	[405]	[298]	4	hSpCas9	negative selection	11356650
22127521	22127544	8	-	28162770	EOL1	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-3.038926352404351	[77]	[4]	-9	hSpCas9	negative selection	11356651
22128874	22128897	8	-	28162770	MOLM13	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.36438317271735465	[145]	[81]	-2	hSpCas9	negative selection	11526008
22127454	22127477	8	+	28162770	MOLM13	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	-1.297645364818398	[271]	[79]	-6	hSpCas9	negative selection	11526009
22127394	22127417	8	-	28162770	MOLM13	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-3.169540539070713	[223]	[17]	-8	hSpCas9	negative selection	11526010
22125581	22125604	8	-	28162770	MOLM13	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.8633740834020223	[259]	[341]	6	hSpCas9	negative selection	11526011
22129143	22129166	8	-	28162770	MOLM13	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.40180019108680637	[267]	[255]	3	hSpCas9	negative selection	11526012
22129031	22129054	8	+	28162770	MOLM13	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.05130534902555699	[267]	[186]	0	hSpCas9	negative selection	11526013
22128939	22128962	8	-	28162770	MOLM13	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-5.509390541955338	[125]	[1]	-9	hSpCas9	negative selection	11526014
22128812	22128835	8	-	28162770	MOLM13	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.8829268808234227	[218]	[291]	6	hSpCas9	negative selection	11526015
22128600	22128623	8	-	28162770	MOLM13	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.5518288530699266	[441]	[217]	-3	hSpCas9	negative selection	11526016
22127521	22127544	8	-	28162770	MOLM13	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-0.2545766429265124	[98]	[59]	-1	hSpCas9	negative selection	11526017
22128874	22128897	8	-	28162770	HEL	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	1.940419380641042	[95]	[235]	9	hSpCas9	negative selection	11695374
22127454	22127477	8	+	28162770	HEL	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.011520740318328032	[205]	[132]	0	hSpCas9	negative selection	11695375
22127394	22127417	8	-	28162770	HEL	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.4343373910182837	[172]	[40]	-7	hSpCas9	negative selection	11695376
22125581	22125604	8	-	28162770	HEL	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.4405950945077145	[282]	[245]	3	hSpCas9	negative selection	11695377
22129143	22129166	8	-	28162770	HEL	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	1.1697181486151045	[219]	[316]	8	hSpCas9	negative selection	11695378
22129031	22129054	8	+	28162770	HEL	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.221606068642077	[283]	[155]	-2	hSpCas9	negative selection	11695379
22128939	22128962	8	-	28162770	HEL	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	0.7200445581678059	[108]	[114]	6	hSpCas9	negative selection	11695380
22128812	22128835	8	-	28162770	HEL	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	-0.06667103964528787	[120]	[73]	0	hSpCas9	negative selection	11695381
22128600	22128623	8	-	28162770	HEL	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	0.6983868615502713	[355]	[369]	6	hSpCas9	negative selection	11695382
22127521	22127544	8	-	28162770	HEL	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	0.3748056267537241	[58]	[48]	3	hSpCas9	negative selection	11695383
22128874	22128897	8	-	28162770	MV411	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.7525624492172246	[121]	[60]	-5	hSpCas9	negative selection	11864740
22127454	22127477	8	+	28162770	MV411	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.3689995306636887	[181]	[197]	3	hSpCas9	negative selection	11864741
22127394	22127417	8	-	28162770	MV411	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-5.0471831981088515	[156]	[3]	-9	hSpCas9	negative selection	11864742
22125581	22125604	8	-	28162770	MV411	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.32468054971523586	[199]	[210]	3	hSpCas9	negative selection	11864743
22129143	22129166	8	-	28162770	MV411	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	-0.10305969630135803	[152]	[119]	-1	hSpCas9	negative selection	11864744
22129031	22129054	8	+	28162770	MV411	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.3934813559123964	[183]	[117]	-3	hSpCas9	negative selection	11864745
22128939	22128962	8	-	28162770	MV411	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-1.1966624140985314	[116]	[42]	-7	hSpCas9	negative selection	11864746
22128812	22128835	8	-	28162770	MV411	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.25756176805648273	[141]	[142]	2	hSpCas9	negative selection	11864747
22128600	22128623	8	-	28162770	MV411	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.9200191950687873	[291]	[129]	-6	hSpCas9	negative selection	11864748
22127521	22127544	8	-	28162770	MV411	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-0.673707028505985	[88]	[46]	-5	hSpCas9	negative selection	11864749
22128874	22128897	8	-	28162770	MONOMAC1	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.461174635692241	[63]	[100]	4	hSpCas9	negative selection	12034106
22127454	22127477	8	+	28162770	MONOMAC1	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.4376786888587019	[113]	[176]	4	hSpCas9	negative selection	12034107
22127394	22127417	8	-	28162770	MONOMAC1	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.0085917576464434	[85]	[48]	-7	hSpCas9	negative selection	12034108
22125581	22125604	8	-	28162770	MONOMAC1	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	0.5017936182198812	[137]	[223]	5	hSpCas9	negative selection	12034109
22129143	22129166	8	-	28162770	MONOMAC1	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.3084911861671976	[111]	[158]	3	hSpCas9	negative selection	12034110
22129031	22129054	8	+	28162770	MONOMAC1	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-0.6500038019707195	[166]	[121]	-5	hSpCas9	negative selection	12034111
22128939	22128962	8	-	28162770	MONOMAC1	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	0.7634347887538087	[36]	[71]	7	hSpCas9	negative selection	12034112
22128812	22128835	8	-	28162770	MONOMAC1	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	0.4044137764501715	[57]	[87]	4	hSpCas9	negative selection	12034113
22128600	22128623	8	-	28162770	MONOMAC1	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.10916409103421931	[206]	[219]	-1	hSpCas9	negative selection	12034114
22127521	22127544	8	-	28162770	MONOMAC1	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-1.2365652112461911	[36]	[17]	-7	hSpCas9	negative selection	12034115
22128874	22128897	8	-	28162770	OCIAML2	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	0.0819111977866176	[14]	[87]	0	hSpCas9	negative selection	12203472
22127454	22127477	8	+	28162770	OCIAML2	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.7399371606974972	[34]	[323]	7	hSpCas9	negative selection	12203473
22127394	22127417	8	-	28162770	OCIAML2	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-3.383166983991822	[31]	[16]	-9	hSpCas9	negative selection	12203474
22125581	22125604	8	-	28162770	OCIAML2	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	-0.5320303699063047	[53]	[206]	-4	hSpCas9	negative selection	12203475
22129143	22129166	8	-	28162770	OCIAML2	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	-0.7899083417155742	[33]	[108]	-5	hSpCas9	negative selection	12203476
22129031	22129054	8	+	28162770	OCIAML2	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-1.111548731937333	[45]	[117]	-6	hSpCas9	negative selection	12203477
22128939	22128962	8	-	28162770	OCIAML2	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-0.770190107101069	[15]	[51]	-5	hSpCas9	negative selection	12203478
22128812	22128835	8	-	28162770	OCIAML2	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	-0.04276828560573365	[20]	[112]	0	hSpCas9	negative selection	12203479
22128600	22128623	8	-	28162770	OCIAML2	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.30351983940690286	[56]	[255]	-2	hSpCas9	negative selection	12203480
22127521	22127544	8	-	28162770	OCIAML2	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	-2.2227023117985754	[15]	[18]	-8	hSpCas9	negative selection	12203481
22128874	22128897	8	-	28162770	OCIAML3	viability	GCAGCAAAGAGGGACTGCGCTGG	HR	ENSG00000168453	-0.7148620351985489	[55]	[102]	-5	hSpCas9	negative selection	12372838
22127454	22127477	8	+	28162770	OCIAML3	viability	AGGATGAACAGCAGCCCCGCTGG	HR	ENSG00000168453	0.7942629493918953	[33]	[177]	7	hSpCas9	negative selection	12372839
22127394	22127417	8	-	28162770	OCIAML3	viability	GAAGTGCCAGGAGGGCCTGGAGG	HR	ENSG00000168453	-1.972519263577893	[38]	[29]	-8	hSpCas9	negative selection	12372840
22125581	22125604	8	-	28162770	OCIAML3	viability	GCCACTCTCAGCAAGTGCGGAGG	HR	ENSG00000168453	1.3145121988690138	[58]	[442]	9	hSpCas9	negative selection	12372841
22129143	22129166	8	-	28162770	OCIAML3	viability	GAGTACGCCCAGCTTCCTGAAGG	HR	ENSG00000168453	0.44161626940655796	[39]	[163]	4	hSpCas9	negative selection	12372842
22129031	22129054	8	+	28162770	OCIAML3	viability	GCAGGCTCTCCCAGGCACAGCGG	HR	ENSG00000168453	-1.302544826163852	[66]	[81]	-7	hSpCas9	negative selection	12372843
22128939	22128962	8	-	28162770	OCIAML3	viability	GGACATGCTCCCACTTGTGGAGG	HR	ENSG00000168453	-0.7076644221197304	[32]	[60]	-5	hSpCas9	negative selection	12372844
22128812	22128835	8	-	28162770	OCIAML3	viability	CCAGCGTGCCCACCTCGCTGTGG	HR	ENSG00000168453	1.165729261500701	[43]	[297]	8	hSpCas9	negative selection	12372845
22128600	22128623	8	-	28162770	OCIAML3	viability	GCACCCCTGGGTATACTCCGGGG	HR	ENSG00000168453	-0.0029706251933224737	[78]	[237]	0	hSpCas9	negative selection	12372846
22127521	22127544	8	-	28162770	OCIAML3	viability	GGAACCTTGGGTACCAGCTGGGG	HR	ENSG00000168453	0.02070220379104515	[15]	[48]	0	hSpCas9	negative selection	12372847