Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:59340
• Symbol:HRH4
• Description:histamine receptor H4

DataSource: http://genomecrispr.dkfz.de/#!/results/HRH4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
24460833	24460856	18	+	26472758	Jiyoye	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	-0.1967079811125112	[306]	[201]	-1	hSpCas9	negative selection	74123
24477253	24477276	18	-	26472758	Jiyoye	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	-1.2302545391094182	[195]	[62]	-7	hSpCas9	negative selection	74124
24460901	24460924	18	-	26472758	Jiyoye	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.9198236774111395	[74]	[106]	6	hSpCas9	negative selection	74125
24477041	24477064	18	+	26472758	Jiyoye	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.03061203004166524	[591]	[455]	0	hSpCas9	negative selection	74126
24476867	24476890	18	+	26472758	Jiyoye	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.5129700455284701	[183]	[197]	4	hSpCas9	negative selection	74127
24477025	24477048	18	-	26472758	Jiyoye	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-1.3166148239125994	[108]	[32]	-7	hSpCas9	negative selection	74128
24476989	24477012	18	-	26472758	Jiyoye	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.9422126568953473	[146]	[212]	6	hSpCas9	negative selection	74129
24477011	24477034	18	+	26472758	Jiyoye	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	1.157197128497526	[43]	[73]	7	hSpCas9	negative selection	74130
24477051	24477074	18	-	26472758	Jiyoye	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.4929825351761439	[358]	[380]	4	hSpCas9	negative selection	74131
24477129	24477152	18	+	26472758	Jiyoye	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	-0.9647933958810845	[131]	[50]	-6	hSpCas9	negative selection	74132
24460833	24460856	18	+	26472758	KBM7	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	0.8282175172549161	[838,510]	[594,513]	8	hSpCas9	negative selection	265241
24477253	24477276	18	-	26472758	KBM7	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	-0.16092233268981723	[667,590]	[228,295]	-1	hSpCas9	negative selection	265242
24460901	24460924	18	-	26472758	KBM7	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	-0.24047630337576398	[360,524]	[236,129]	-2	hSpCas9	negative selection	265243
24477041	24477064	18	+	26472758	KBM7	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.49033794787989615	[2445,1773]	[1155,1575]	5	hSpCas9	negative selection	265244
24476867	24476890	18	+	26472758	KBM7	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.24018623179570453	[975,530]	[334,472]	2	hSpCas9	negative selection	265245
24477025	24477048	18	-	26472758	KBM7	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.12232469093947873	[302,222]	[104,118]	-1	hSpCas9	negative selection	265246
24476989	24477012	18	-	26472758	KBM7	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.4539431032663399	[1040,1141]	[931,510]	5	hSpCas9	negative selection	265247
24477011	24477034	18	+	26472758	KBM7	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.7812491352590066	[290,237]	[210,213]	8	hSpCas9	negative selection	265248
24477051	24477074	18	-	26472758	KBM7	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	-0.2149388500702205	[2353,2245]	[1074,807]	-2	hSpCas9	negative selection	265249
24477129	24477152	18	+	26472758	KBM7	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.7687099961888272	[452,466]	[448,300]	8	hSpCas9	negative selection	265250
24460833	24460856	18	+	26472758	Raji	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.070389327891398	[315]	[153]	8	hSpCas9	negative selection	456359
24477253	24477276	18	-	26472758	Raji	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.872554010798929	[232]	[98]	7	hSpCas9	negative selection	456360
24460901	24460924	18	-	26472758	Raji	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.5167073834580497	[252]	[83]	5	hSpCas9	negative selection	456361
24477041	24477064	18	+	26472758	Raji	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.5952867658100409	[1080]	[378]	5	hSpCas9	negative selection	456362
24476867	24476890	18	+	26472758	Raji	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.3928882220110881	[360]	[109]	4	hSpCas9	negative selection	456363
24477025	24477048	18	-	26472758	Raji	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.10206983025535044	[147]	[31]	-1	hSpCas9	negative selection	456364
24476989	24477012	18	-	26472758	Raji	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.2612610584207933	[407]	[78]	-2	hSpCas9	negative selection	456365
24477011	24477034	18	+	26472758	Raji	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.6792898832693093	[147]	[54]	6	hSpCas9	negative selection	456366
24477051	24477074	18	-	26472758	Raji	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.17057736186079353	[1071]	[279]	1	hSpCas9	negative selection	456367
24477129	24477152	18	+	26472758	Raji	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	-0.31540623962943104	[310]	[57]	-3	hSpCas9	negative selection	456368
24460833	24460856	18	+	26472758	K562	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.1386084445674336	[501]	[932]	8	hSpCas9	negative selection	647477
24477253	24477276	18	-	26472758	K562	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	-0.004445905031192147	[384]	[323]	0	hSpCas9	negative selection	647478
24460901	24460924	18	-	26472758	K562	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.5153504637203621	[333]	[402]	4	hSpCas9	negative selection	647479
24477041	24477064	18	+	26472758	K562	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	-0.21832204923140175	[1854]	[1345]	-1	hSpCas9	negative selection	647480
24476867	24476890	18	+	26472758	K562	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.857083254025711	[532]	[814]	7	hSpCas9	negative selection	647481
24477025	24477048	18	-	26472758	K562	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	0.2101488255817009	[212]	[207]	1	hSpCas9	negative selection	647482
24476989	24477012	18	-	26472758	K562	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.0949190454805443	[791]	[625]	0	hSpCas9	negative selection	647483
24477011	24477034	18	+	26472758	K562	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.8129867901369344	[235]	[349]	6	hSpCas9	negative selection	647484
24477051	24477074	18	-	26472758	K562	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	-0.454268207289944	[1747]	[1076]	-3	hSpCas9	negative selection	647485
24477129	24477152	18	+	26472758	K562	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.7387358639476027	[415]	[585]	6	hSpCas9	negative selection	647486
24468802	24468825	18	-	26627737	DLD1	viability	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.2721428880449014	[1106]	[274,314,272]	-3	hSpCas9	negative selection	801235
24468812	24468835	18	+	26627737	DLD1	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.38924052751238714	[948]	[344,418,400]	4	hSpCas9	negative selection	801236
24476867	24476890	18	+	26627737	DLD1	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.095286050291543	[267]	[145,134,243]	8	hSpCas9	negative selection	801237
24476911	24476934	18	-	26627737	DLD1	viability	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.1288162664436907	[1455]	[331,418,486]	-1	hSpCas9	negative selection	801238
24477264	24477287	18	+	26627737	DLD1	viability	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	1.049292354698099	[194]	[114,201,72]	8	hSpCas9	negative selection	801239
24468802	24468825	18	-	26627737	GBM cells	viability after 5 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.3184527663994703	[399]	[285,248]	5	hSpCas9	negative selection	883550
24468812	24468835	18	+	26627737	GBM cells	viability after 5 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5071193761189171	[430]	[354,301]	7	hSpCas9	negative selection	883551
24476867	24476890	18	+	26627737	GBM cells	viability after 5 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.9940711079260258	[131]	[133,147]	9	hSpCas9	negative selection	883552
24476911	24476934	18	-	26627737	GBM cells	viability after 5 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.37920756544163736	[361]	[213,290]	6	hSpCas9	negative selection	883553
24477264	24477287	18	+	26627737	GBM cells	viability after 5 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.05464968720706559	[192]	[90,123]	0	hSpCas9	negative selection	883554
24468802	24468825	18	-	26627737	GBM cells	viability after 13 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.44389645984542225	[399]	[399,209]	5	hSpCas9	negative selection	965865
24468812	24468835	18	+	26627737	GBM cells	viability after 13 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.22417081355233093	[430]	[249,291]	3	hSpCas9	negative selection	965866
24476867	24476890	18	+	26627737	GBM cells	viability after 13 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.786763233456172	[131]	[138,110]	8	hSpCas9	negative selection	965867
24476911	24476934	18	-	26627737	GBM cells	viability after 13 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.677013113475844	[361]	[302,322]	7	hSpCas9	negative selection	965868
24477264	24477287	18	+	26627737	GBM cells	viability after 13 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.39501542799309347	[192]	[156,121]	5	hSpCas9	negative selection	965869
24468802	24468825	18	-	26627737	GBM cells	viability after 21 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.24536589306818846	[399]	[266,248]	2	hSpCas9	negative selection	1048180
24468812	24468835	18	+	26627737	GBM cells	viability after 21 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.8506997969462317	[430]	[415,427]	8	hSpCas9	negative selection	1048181
24476867	24476890	18	+	26627737	GBM cells	viability after 21 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.4364128997077855	[131]	[95,97]	4	hSpCas9	negative selection	1048182
24476911	24476934	18	-	26627737	GBM cells	viability after 21 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.7761833347746957	[361]	[352,321]	7	hSpCas9	negative selection	1048183
24477264	24477287	18	+	26627737	GBM cells	viability after 21 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.5369687430277412	[192]	[148,154]	5	hSpCas9	negative selection	1048184
24468802	24468825	18	-	26627737	RPE1	viability after 9 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.018176367984035657	[1900]	[479,760]	0	hSpCas9	negative selection	1130495
24468812	24468835	18	+	26627737	RPE1	viability after 9 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	1.4036569982886802	[1379]	[946,1395]	7	hSpCas9	negative selection	1130496
24476867	24476890	18	+	26627737	RPE1	viability after 9 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.10235401015356715	[282]	[119,62]	0	hSpCas9	negative selection	1130497
24476911	24476934	18	-	26627737	RPE1	viability after 9 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.4473645147108775	[828]	[359,345]	3	hSpCas9	negative selection	1130498
24477264	24477287	18	+	26627737	RPE1	viability after 9 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.4503972956423007	[517]	[173,282]	3	hSpCas9	negative selection	1130499
24468802	24468825	18	-	26627737	RPE1	viability after 12 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.15867593724543916	[1900]	[488,655]	1	hSpCas9	negative selection	1212810
24468812	24468835	18	+	26627737	RPE1	viability after 12 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	1.0050946597007047	[1379]	[731,756]	6	hSpCas9	negative selection	1212811
24476867	24476890	18	+	26627737	RPE1	viability after 12 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.1820251934099142	[282]	[240,99]	7	hSpCas9	negative selection	1212812
24476911	24476934	18	-	26627737	RPE1	viability after 12 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.020332343052034435	[828]	[272,175]	0	hSpCas9	negative selection	1212813
24477264	24477287	18	+	26627737	RPE1	viability after 12 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.9828906820445811	[517]	[242,308]	6	hSpCas9	negative selection	1212814
24468802	24468825	18	-	26627737	RPE1	viability after 15 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.4513304206863964	[1900]	[888,586]	3	hSpCas9	negative selection	1295125
24468812	24468835	18	+	26627737	RPE1	viability after 15 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.9363044493262815	[1379]	[801,693]	5	hSpCas9	negative selection	1295126
24476867	24476890	18	+	26627737	RPE1	viability after 15 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.014641903447370153	[282]	[59,100]	0	hSpCas9	negative selection	1295127
24476911	24476934	18	-	26627737	RPE1	viability after 15 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.6933236856449881	[828]	[339,416]	4	hSpCas9	negative selection	1295128
24477264	24477287	18	+	26627737	RPE1	viability after 15 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.8503111070993884	[517]	[225,300]	5	hSpCas9	negative selection	1295129
24468802	24468825	18	-	26627737	RPE1	viability after 18 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.32144465177579806	[1900]	[671,607]	2	hSpCas9	negative selection	1377440
24468812	24468835	18	+	26627737	RPE1	viability after 18 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.7233358578322602	[1379]	[639,587]	4	hSpCas9	negative selection	1377441
24476867	24476890	18	+	26627737	RPE1	viability after 18 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.4440684420380303	[282]	[100,106]	3	hSpCas9	negative selection	1377442
24476911	24476934	18	-	26627737	RPE1	viability after 18 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.7738542186388515	[828]	[528,225]	5	hSpCas9	negative selection	1377443
24477264	24477287	18	+	26627737	RPE1	viability after 18 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.05319339143651225	[517]	[87,205]	0	hSpCas9	negative selection	1377444
24468802	24468825	18	-	26627737	HeLa	viability after 8 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.6430111657205464	[845]	[403,174,169]	-6	hSpCas9	negative selection	1459755
24468812	24468835	18	+	26627737	HeLa	viability after 8 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.7462402730977736	[1084]	[461,227,199]	-6	hSpCas9	negative selection	1459756
24476867	24476890	18	+	26627737	HeLa	viability after 8 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.09347631645910065	[355]	[226,273,18]	0	hSpCas9	negative selection	1459757
24476911	24476934	18	-	26627737	HeLa	viability after 8 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.6133879884796133	[1107]	[297,288,351]	-6	hSpCas9	negative selection	1459758
24477264	24477287	18	+	26627737	HeLa	viability after 8 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	-0.12833422539735972	[370]	[177,186,88]	-1	hSpCas9	negative selection	1459759
24468802	24468825	18	-	26627737	HeLa	viability after 12 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.8218136441526682	[845]	[147,215,225]	-6	hSpCas9	negative selection	1542070
24468812	24468835	18	+	26627737	HeLa	viability after 12 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.3507266247669898	[1084]	[490,265,310]	-3	hSpCas9	negative selection	1542071
24476867	24476890	18	+	26627737	HeLa	viability after 12 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	-0.3462176099562282	[355]	[38,105,200]	-3	hSpCas9	negative selection	1542072
24476911	24476934	18	-	26627737	HeLa	viability after 12 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.5771154250553993	[1107]	[263,245,415]	-5	hSpCas9	negative selection	1542073
24477264	24477287	18	+	26627737	HeLa	viability after 12 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.09184425008869057	[370]	[19,191,270]	0	hSpCas9	negative selection	1542074
24468802	24468825	18	-	26627737	HeLa	viability after 15 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.3128808526345944	[845]	[215,309,308]	-3	hSpCas9	negative selection	1624385
24468812	24468835	18	+	26627737	HeLa	viability after 15 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.88954233779874	[1084]	[181,186,355]	-7	hSpCas9	negative selection	1624386
24476867	24476890	18	+	26627737	HeLa	viability after 15 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	-0.16958701764533582	[355]	[66,207,110]	-1	hSpCas9	negative selection	1624387
24476911	24476934	18	-	26627737	HeLa	viability after 15 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.2999906110668584	[1107]	[238,492,368]	-3	hSpCas9	negative selection	1624388
24477264	24477287	18	+	26627737	HeLa	viability after 15 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	-0.009871367380394527	[370]	[101,157,193]	0	hSpCas9	negative selection	1624389
24468802	24468825	18	-	26627737	HeLa	viability after 18 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.29871758606417287	[845]	[141,266,308]	-3	hSpCas9	negative selection	1706700
24468812	24468835	18	+	26627737	HeLa	viability after 18 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.8672825134196506	[1084]	[121,163,355]	-6	hSpCas9	negative selection	1706701
24476867	24476890	18	+	26627737	HeLa	viability after 18 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	-0.14979786755500243	[355]	[46,173,110]	-1	hSpCas9	negative selection	1706702
24476911	24476934	18	-	26627737	HeLa	viability after 18 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.3547309280882063	[1107]	[145,392,368]	-3	hSpCas9	negative selection	1706703
24477264	24477287	18	+	26627737	HeLa	viability after 18 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.00634805838947558	[370]	[69,132,193]	0	hSpCas9	negative selection	1706704
24468802	24468825	18	-	26627737	HCT116	viability after 6 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.4198116953613966	[1156]	[310,205]	2	hSpCas9	negative selection	1789015
24468812	24468835	18	+	26627737	HCT116	viability after 6 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.4552260710595363	[739]	[167,38]	-3	hSpCas9	negative selection	1789016
24476867	24476890	18	+	26627737	HCT116	viability after 6 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	-1.2324012083246751	[602]	[98,7]	-6	hSpCas9	negative selection	1789017
24476911	24476934	18	-	26627737	HCT116	viability after 6 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.1667179213662161	[1192]	[217,138]	-1	hSpCas9	negative selection	1789018
24477264	24477287	18	+	26627737	HCT116	viability after 6 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	1.012810184712568	[373]	[282,27]	5	hSpCas9	negative selection	1789019
24468802	24468825	18	-	26627737	HCT116	viability after 8 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.21256563994704136	[529]	[255,357,398]	2	hSpCas9	negative selection	1871330
24468812	24468835	18	+	26627737	HCT116	viability after 8 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5730464143039777	[324]	[331,249,218]	6	hSpCas9	negative selection	1871331
24476867	24476890	18	+	26627737	HCT116	viability after 8 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.0594098115469188	[164]	[107,269,188]	8	hSpCas9	negative selection	1871332
24476911	24476934	18	-	26627737	HCT116	viability after 8 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.023641588639015554	[467]	[259,314,211]	0	hSpCas9	negative selection	1871333
24477264	24477287	18	+	26627737	HCT116	viability after 8 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	-0.09312613599599248	[328]	[204,94,209]	-1	hSpCas9	negative selection	1871334
24468802	24468825	18	-	26627737	HCT116	viability after 9 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.16438369221217863	[1156]	[448,264]	1	hSpCas9	negative selection	1953645
24468812	24468835	18	+	26627737	HCT116	viability after 9 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5921224987925717	[739]	[384,228]	4	hSpCas9	negative selection	1953646
24476867	24476890	18	+	26627737	HCT116	viability after 9 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	-0.6573253605186236	[602]	[105,98]	-5	hSpCas9	negative selection	1953647
24476911	24476934	18	-	26627737	HCT116	viability after 9 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.05604476348453147	[1192]	[443,241]	0	hSpCas9	negative selection	1953648
24477264	24477287	18	+	26627737	HCT116	viability after 9 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	1.7168752322893122	[373]	[234,401]	9	hSpCas9	negative selection	1953649
24468802	24468825	18	-	26627737	HCT116	viability after 12 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.03941657862412862	[529]	[242,372,201]	0	hSpCas9	negative selection	2035960
24468812	24468835	18	+	26627737	HCT116	viability after 12 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	1.0398515309930232	[324]	[337,324,390]	8	hSpCas9	negative selection	2035961
24476867	24476890	18	+	26627737	HCT116	viability after 12 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.1421742122036587	[164]	[199,174,197]	8	hSpCas9	negative selection	2035962
24476911	24476934	18	-	26627737	HCT116	viability after 12 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.6445779972240095	[467]	[402,432,316]	6	hSpCas9	negative selection	2035963
24477264	24477287	18	+	26627737	HCT116	viability after 12 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.41589228761159697	[328]	[315,85,278]	4	hSpCas9	negative selection	2035964
24468802	24468825	18	-	26627737	HCT116	viability after 15 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.14434363863240962	[529]	[382,387,244]	1	hSpCas9	negative selection	2118275
24468812	24468835	18	+	26627737	HCT116	viability after 15 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	1.1247933211313048	[324]	[430,470,322]	8	hSpCas9	negative selection	2118276
24476867	24476890	18	+	26627737	HCT116	viability after 15 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.0281740066534266	[164]	[209,194,176]	8	hSpCas9	negative selection	2118277
24476911	24476934	18	-	26627737	HCT116	viability after 15 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.7523851391587411	[467]	[352,610,382]	6	hSpCas9	negative selection	2118278
24477264	24477287	18	+	26627737	HCT116	viability after 15 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	-0.012158902647516456	[328]	[218,82,262]	0	hSpCas9	negative selection	2118279
24468802	24468825	18	-	26627737	HCT116	viability after 18 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.36161004402379826	[529]	[214,415,351]	3	hSpCas9	negative selection	2200590
24468812	24468835	18	+	26627737	HCT116	viability after 18 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.732566359140855	[324]	[270,138,386]	6	hSpCas9	negative selection	2200591
24476867	24476890	18	+	26627737	HCT116	viability after 18 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.4344169324463305	[164]	[169,163,320]	8	hSpCas9	negative selection	2200592
24476911	24476934	18	-	26627737	HCT116	viability after 18 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.48003600354167575	[467]	[156,463,315]	4	hSpCas9	negative selection	2200593
24477264	24477287	18	+	26627737	HCT116	viability after 18 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.35681211937760543	[328]	[289,65,266]	3	hSpCas9	negative selection	2200594
24477057	24477080	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCTGTGGACACTCATTCAGAGG	HRH4	ENSG00000134489	0.1505200059137671	[3,4]	[3,4]	3	hSpCas9	positive selection	2994164
24460901	24460924	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	-0.14622012043811844	[4,4]	[4,2]	-2	hSpCas9	positive selection	2994165
24477042	24477065	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.6070984663141195	[3,3]	[3,5]	9	hSpCas9	positive selection	2994166
24476995	24477018	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	0.17223469034318079	[4,3]	[3,4]	3	hSpCas9	positive selection	2994167
24477057	24477080	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCTGTGGACACTCATTCAGAGG	HRH4	ENSG00000134489	0.2185405659986081	[3,3]	[4,2]	4	hSpCas9	positive selection	3062022
24460901	24460924	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	0.10005594911586446	[4,4]	[4,2]	1	hSpCas9	positive selection	3062023
24477042	24477065	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	-0.16973084589977333	[3,3]	[3,0]	-2	hSpCas9	positive selection	3062024
24476995	24477018	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-0.23372848307605987	[4,4]	[4,1]	-3	hSpCas9	positive selection	3062025
24460863	24460886		-	24336571	A375	resistance to PLX after 7 days	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.08087917328965491	[13,11]	[13,10]	-2	hSpCas9	positive selection	3119786
24476994	24477017		+	24336571	A375	resistance to PLX after 7 days	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	0.030379783141842087	[18,12]	[16,15]	1	hSpCas9	positive selection	3119787
24477469	24477492		+	24336571	A375	resistance to PLX after 7 days	GTGTCACAAGCGCTTTCAAAAGG	HRH4	ENSG00000134489	-0.016068117252331482	[9,10]	[9,10]	0	hSpCas9	positive selection	3119788
24468814	24468837		-	24336571	A375	resistance to PLX after 7 days	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.19717560784592192	[26,27]	[29,32]	6	hSpCas9	positive selection	3119789
24468812	24468835		+	24336571	A375	resistance to PLX after 7 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.05885560227193176	[18,20]	[20,20]	2	hSpCas9	positive selection	3119790
24460863	24460886		-	24336571	A375	resistance to PLX after 14 days	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.7348274887919044	[15,11]	[9,11]	6	hSpCas9	positive selection	3177579
24476994	24477017		+	24336571	A375	resistance to PLX after 14 days	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-0.40927372984284377	[17,12]	[4,4]	-5	hSpCas9	positive selection	3177580
24477469	24477492		+	24336571	A375	resistance to PLX after 14 days	GTGTCACAAGCGCTTTCAAAAGG	HRH4	ENSG00000134489	-0.15234229134636096	[10,13]	[4,4]	-1	hSpCas9	positive selection	3177581
24468814	24468837		-	24336571	A375	resistance to PLX after 14 days	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.21741937611545414	[24,29]	[16,12]	2	hSpCas9	positive selection	3177582
24468812	24468835		+	24336571	A375	resistance to PLX after 14 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.4720236014738486	[17,26]	[7,5]	-5	hSpCas9	positive selection	3177583
24460863	24460886		-	24336571	A375	viability after 7 days	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.1325551992825001	[14]	[13,11]	-2	hSpCas9	negative selection	3235372
24476994	24477017		+	24336571	A375	viability after 7 days	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-0.5061353075558983	[23]	[18,12]	-6	hSpCas9	negative selection	3235373
24477469	24477492		+	24336571	A375	viability after 7 days	GTGTCACAAGCGCTTTCAAAAGG	HRH4	ENSG00000134489	-0.3647687785794144	[13]	[9,10]	-5	hSpCas9	negative selection	3235374
24468814	24468837		-	24336571	A375	viability after 7 days	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.8831719477856322	[15]	[26,27]	9	hSpCas9	negative selection	3235375
24468812	24468835		+	24336571	A375	viability after 7 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5033555532126773	[14]	[18,20]	7	hSpCas9	negative selection	3235376
24460863	24460886		-	24336571	A375	viability after 14 days	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.007426924681725955	[14]	[15,11]	0	hSpCas9	negative selection	3293165
24476994	24477017		+	24336571	A375	viability after 14 days	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-0.5325889999451066	[23]	[17,12]	-6	hSpCas9	negative selection	3293166
24477469	24477492		+	24336571	A375	viability after 14 days	GTGTCACAAGCGCTTTCAAAAGG	HRH4	ENSG00000134489	-0.10293046211726209	[13]	[10,13]	-1	hSpCas9	negative selection	3293167
24468814	24468837		-	24336571	A375	viability after 14 days	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.9002839881516266	[15]	[24,29]	9	hSpCas9	negative selection	3293168
24468812	24468835		+	24336571	A375	viability after 14 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.6771610044751513	[14]	[17,26]	8	hSpCas9	negative selection	3293169
24468812	24468835	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.800039226830485	[67,107]	[0,0]	4	hSpCas9	positive selection	3354065
24468814	24468837	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	1.2554121390589754	[76,50]	[0,0]	5	hSpCas9	positive selection	3354066
24460863	24460886	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	1.4868080575686025	[67,40]	[0,0]	6	hSpCas9	positive selection	3354067
24477072	24477095	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.5240335020788246	[219,219]	[0,0]	-3	hSpCas9	positive selection	3373287
24477464	24477487	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.22390320990838475	[130,130]	[0,0]	1	hSpCas9	positive selection	3373288
24460732	24460755	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-1.2544264423215443	[364,364]	[0,0]	-8	hSpCas9	positive selection	3373289
24477056	24477079	18	+	26780180	HT29	viability (Avana library 4 designs)	ATCTGTGGACACTCATTCAGAGG	HRH4	ENSG00000134489	1.50958117051059	[]	[]	6	hSpCas9	negative selection	3431460
24460900	24460923	18	+	26780180	HT29	viability (Avana library 4 designs)	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	-0.00273721097620479	[]	[]	0	hSpCas9	negative selection	3431461
24477041	24477064	18	+	26780180	HT29	viability (Avana library 4 designs)	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	2.02844933992197	[]	[]	7	hSpCas9	negative selection	3431462
24476994	24477017	18	+	26780180	HT29	viability (Avana library 4 designs)	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	1.31021588838897	[]	[]	5	hSpCas9	negative selection	3431463
24460900	24460923	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	3.99653910558822	[]	[]	6	hSpCas9	negative selection	3517118
24476994	24477017	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-2.70233725238969	[]	[]	-3	hSpCas9	negative selection	3517119
24477056	24477079	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATCTGTGGACACTCATTCAGAGG	HRH4	ENSG00000134489	2.12233285673934	[]	[]	3	hSpCas9	negative selection	3517120
24477041	24477064	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	4.71285196776052	[]	[]	7	hSpCas9	negative selection	3517121
24476842	24476865	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTAGTTTCAGAGTCTTGGAAGG	HRH4	ENSG00000134489	-1.66605904506841	[]	[]	-2	hSpCas9	negative selection	3517122
24477072	24477095	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-1.98731271085267	[]	[]	-2	hSpCas9	negative selection	3517123
24460900	24460923	18	+	26780180	A375	viability (Avana lentiGuide)	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	-4.2064746335699	[]	[]	-7	hSpCas9	negative selection	3625777
24476994	24477017	18	+	26780180	A375	viability (Avana lentiGuide)	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	4.74473188214175	[]	[]	4	hSpCas9	negative selection	3625778
24477056	24477079	18	+	26780180	A375	viability (Avana lentiGuide)	ATCTGTGGACACTCATTCAGAGG	HRH4	ENSG00000134489	-1.37089397326842	[]	[]	-2	hSpCas9	negative selection	3625779
24477041	24477064	18	+	26780180	A375	viability (Avana lentiGuide)	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	-2.09330217839804	[]	[]	-4	hSpCas9	negative selection	3625780
24476842	24476865	18	+	26780180	A375	viability (Avana lentiGuide)	TCTAGTTTCAGAGTCTTGGAAGG	HRH4	ENSG00000134489	2.15072939551799	[]	[]	2	hSpCas9	negative selection	3625781
24477072	24477095	18	+	26780180	A375	viability (Avana lentiGuide)	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-3.43792480944668	[]	[]	-6	hSpCas9	negative selection	3625782
24460900	24460923	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	0.21669832187468974	[5]	[6,5]	6	hSpCas9	positive selection	3734436
24476994	24477017	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-0.1466648942131315	[4]	[4,2]	-2	hSpCas9	positive selection	3734437
24477056	24477079	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCTGTGGACACTCATTCAGAGG	HRH4	ENSG00000134489	-0.1746959588361707	[6]	[6,4]	-3	hSpCas9	positive selection	3734438
24477041	24477064	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.06814441770320573	[4]	[5,4]	1	hSpCas9	positive selection	3734439
24476842	24476865	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTAGTTTCAGAGTCTTGGAAGG	HRH4	ENSG00000134489	-0.05792452947929906	[5]	[5,5]	-1	hSpCas9	positive selection	3734440
24477072	24477095	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.031832239034571996	[5]	[5,5]	0	hSpCas9	positive selection	3734441
24460900	24460923	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	-0.024993486230120363	[5]	[3,6]	0	hSpCas9	positive selection	3843043
24476994	24477017	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-0.07861778926367903	[5]	[5,3]	-1	hSpCas9	positive selection	3843044
24477056	24477079	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCTGTGGACACTCATTCAGAGG	HRH4	ENSG00000134489	0.1035003593852834	[6]	[6,3]	2	hSpCas9	positive selection	3843045
24477041	24477064	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.3385528995802217	[4]	[5,4]	8	hSpCas9	positive selection	3843046
24476842	24476865	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTAGTTTCAGAGTCTTGGAAGG	HRH4	ENSG00000134489	0.23044245121948256	[5]	[5,5]	6	hSpCas9	positive selection	3843047
24477072	24477095	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.10534654231608695	[4]	[6,2]	2	hSpCas9	positive selection	3843048
24460863	24460886	18	-	26780180	A375	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.989064270604284	[]	[]	4	hSpCas9	negative selection	3949102
24477072	24477095	18	+	26780180	A375	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.713206069719316	[]	[]	2	hSpCas9	negative selection	3949103
24468814	24468837	18	-	26780180	A375	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.619176483499448	[]	[]	2	hSpCas9	negative selection	3949104
24468812	24468835	18	+	26780180	A375	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.467816353186331	[]	[]	1	hSpCas9	negative selection	3949105
24477464	24477487	18	-	26780180	A375	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	1.05039470063154	[]	[]	5	hSpCas9	negative selection	3949106
24460732	24460755	18	-	26780180	A375	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	1.17969331557279	[]	[]	6	hSpCas9	negative selection	3949107
24460863	24460886	18	-	26780180	HT29	viability (GeCKOv2 library)	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.806460723626061	[]	[]	3	hSpCas9	negative selection	4057068
24477072	24477095	18	+	26780180	HT29	viability (GeCKOv2 library)	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.723382576768212	[]	[]	2	hSpCas9	negative selection	4057069
24468814	24468837	18	-	26780180	HT29	viability (GeCKOv2 library)	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.448504132816035	[]	[]	1	hSpCas9	negative selection	4057070
24468812	24468835	18	+	26780180	HT29	viability (GeCKOv2 library)	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	1.20166218434681	[]	[]	6	hSpCas9	negative selection	4057071
24477464	24477487	18	-	26780180	HT29	viability (GeCKOv2 library)	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.996391751580678	[]	[]	4	hSpCas9	negative selection	4057072
24460732	24460755	18	-	26780180	HT29	viability (GeCKOv2 library)	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	1.17370537244084	[]	[]	5	hSpCas9	negative selection	4057073
24460863	24460886	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.4954791949537683	[3]	[3,3]	9	hSpCas9	positive selection	4143340
24476994	24477017	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	-0.04935626145753242	[3]	[2,2]	-1	hSpCas9	positive selection	4143341
24477469	24477492	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGTCACAAGCGCTTTCAAAAGG	HRH4	ENSG00000134489	0.034454143720394126	[3]	[2,2]	0	hSpCas9	positive selection	4143342
24468814	24468837	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.0760705132353292	[4]	[3,3]	2	hSpCas9	positive selection	4143343
24468812	24468835	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.13386223142429923	[3]	[2,2]	3	hSpCas9	positive selection	4143344
24460863	24460886	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.40705414337498996	[3]	[2,0,1,0]	-6	hSpCas9	positive selection	4207362
24476994	24477017	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGAAGCGTGATCATCTCAGTAGG	HRH4	ENSG00000134489	1.2214982755414416	[4]	[3,3,2,4]	8	hSpCas9	positive selection	4207363
24477469	24477492	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGTCACAAGCGCTTTCAAAAGG	HRH4	ENSG00000134489	-0.09325662550578238	[4]	[1,2,2,0]	-1	hSpCas9	positive selection	4207364
24468814	24468837	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	1.001065112089009	[3]	[3,2,1,4]	7	hSpCas9	positive selection	4207365
24468812	24468835	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	1.1336649737134714	[4]	[3,2,4,4]	8	hSpCas9	positive selection	4207366
24468812	24468835	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.26621376389206663	[2]	[2,2]	5	hSpCas9	positive selection	4275782
24468814	24468837	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.16328438972202233	[2]	[2,1]	3	hSpCas9	positive selection	4275783
24460863	24460886	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.048192503072950754	[1]	[2,0]	-1	hSpCas9	positive selection	4275784
24477072	24477095	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.006296023311560331	[3]	[4,1]	0	hSpCas9	positive selection	4340042
24477464	24477487	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.43145699392495196	[2]	[2,2]	8	hSpCas9	positive selection	4340043
24460732	24460755	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.20514302411161822	[3]	[3,1]	-4	hSpCas9	positive selection	4340044
24460863	24460885	18	-	27760321	OCIAML3	viability	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.31796508658523503	[44,44]	[53,30]	3	hSpCas9	negative selection	4408015
24476885	24476907	18	-	27760321	OCIAML3	viability	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	1.108012489946383	[129,103]	[166,233]	9	hSpCas9	negative selection	4408016
24476945	24476967	18	-	27760321	OCIAML3	viability	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-1.1627982132080974	[125,89]	[55,12]	-8	hSpCas9	negative selection	4408017
24476974	24476996	18	+	27760321	OCIAML3	viability	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	1.0907444597296077	[250,247]	[289,581]	9	hSpCas9	negative selection	4408018
24476989	24477011	18	-	27760321	OCIAML3	viability	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.07586089999643303	[353,322]	[185,399]	0	hSpCas9	negative selection	4408019
24460863	24460885	18	-	27760321	OCIAML2	viability	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.5047524782440034	[44,44]	[56,44]	7	hSpCas9	negative selection	4491478
24476885	24476907	18	-	27760321	OCIAML2	viability	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	1.2432773239015353	[129,103]	[236,203]	9	hSpCas9	negative selection	4491479
24476945	24476967	18	-	27760321	OCIAML2	viability	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-0.4427737138248449	[125,89]	[57,70]	-5	hSpCas9	negative selection	4491480
24476974	24476996	18	+	27760321	OCIAML2	viability	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	0.4415076627443215	[250,247]	[273,275]	6	hSpCas9	negative selection	4491481
24476989	24477011	18	-	27760321	OCIAML2	viability	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.06865803555199351	[353,322]	[200,339]	-1	hSpCas9	negative selection	4491482
24460863	24460885	18	-	27760321	MV411	viability	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.19701710484017587	[44,44]	[13,43]	-1	hSpCas9	negative selection	4574941
24476885	24476907	18	-	27760321	MV411	viability	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	0.6758904461467481	[129,103]	[154,73]	5	hSpCas9	negative selection	4574942
24476945	24476967	18	-	27760321	MV411	viability	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-0.7135875910221929	[125,89]	[52,27]	-5	hSpCas9	negative selection	4574943
24476974	24476996	18	+	27760321	MV411	viability	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	0.5871901486747804	[250,247]	[295,175]	4	hSpCas9	negative selection	4574944
24476989	24477011	18	-	27760321	MV411	viability	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.8199013199013978	[353,322]	[316,509]	6	hSpCas9	negative selection	4574945
24460863	24460885	18	-	27760321	HL60	viability	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-1.4946167676752116	[44,44]	[15,9]	-8	hSpCas9	negative selection	4658404
24476885	24476907	18	-	27760321	HL60	viability	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	0.11480631499488392	[129,103]	[65,141]	1	hSpCas9	negative selection	4658405
24476945	24476967	18	-	27760321	HL60	viability	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-0.8104360267861739	[125,89]	[25,74]	-7	hSpCas9	negative selection	4658406
24476974	24476996	18	+	27760321	HL60	viability	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-0.047490013356788374	[250,247]	[222,170]	0	hSpCas9	negative selection	4658407
24476989	24477011	18	-	27760321	HL60	viability	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.029075650010810694	[353,322]	[331,228]	0	hSpCas9	negative selection	4658408
24460863	24460885	18	-	27760321	HT1080	viability	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-3.9938032550165907	[44,34]	[0,0]	-8	hSpCas9	negative selection	4741867
24476885	24476907	18	-	27760321	HT1080	viability	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	0.03499227405992	[103,80]	[42,31]	0	hSpCas9	negative selection	4741868
24476945	24476967	18	-	27760321	HT1080	viability	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-0.6852580927400465	[89,69]	[36,0]	-3	hSpCas9	negative selection	4741869
24476974	24476996	18	+	27760321	HT1080	viability	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	1.0409709840191232	[247,193]	[205,153]	5	hSpCas9	negative selection	4741870
24476989	24477011	18	-	27760321	HT1080	viability	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.9022030167645736	[322,251]	[214,212]	5	hSpCas9	negative selection	4741871
24460863	24460885	18	-	27760321	HT29	viability after 7 days	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-1.1811176926938378	[44,34]	[60,6,5]	-8	hSpCas9	negative selection	4825330
24476885	24476907	18	-	27760321	HT29	viability after 7 days	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	0.31781886815958593	[103,80]	[128,173,138]	5	hSpCas9	negative selection	4825331
24476945	24476967	18	-	27760321	HT29	viability after 7 days	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-2.179984251013771	[89,69]	[11,46,7]	-9	hSpCas9	negative selection	4825332
24476974	24476996	18	+	27760321	HT29	viability after 7 days	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-0.9935384700740773	[247,193]	[205,119,111]	-8	hSpCas9	negative selection	4825333
24476989	24477011	18	-	27760321	HT29	viability after 7 days	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.2824075990450315	[322,251]	[482,249,206]	-4	hSpCas9	negative selection	4825334
24460863	24460885	18	-	27760321	HT29	viability after 25 days	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.9684341423209224	[44,34]	[17,14,38]	-6	hSpCas9	negative selection	4908793
24476885	24476907	18	-	27760321	HT29	viability after 25 days	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	0.34191283537274897	[103,80]	[113,76,220]	3	hSpCas9	negative selection	4908794
24476945	24476967	18	-	27760321	HT29	viability after 25 days	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	0.34563959193877447	[89,69]	[130,128,83]	3	hSpCas9	negative selection	4908795
24476974	24476996	18	+	27760321	HT29	viability after 25 days	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-0.3626581363693311	[247,193]	[186,254,141]	-4	hSpCas9	negative selection	4908796
24476989	24477011	18	-	27760321	HT29	viability after 25 days	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.408515676766169	[322,251]	[292,437,602]	4	hSpCas9	negative selection	4908797
24460863	24460885	18	-	27760321	HT29	viability after 22 days	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.9830041461081658	[44,34]	[25,30,12]	-6	hSpCas9	negative selection	4992256
24476885	24476907	18	-	27760321	HT29	viability after 22 days	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	0.15282190052171463	[103,80]	[114,91,149]	1	hSpCas9	negative selection	4992257
24476945	24476967	18	-	27760321	HT29	viability after 22 days	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-1.0460122838484067	[89,69]	[84,29,17]	-6	hSpCas9	negative selection	4992258
24476974	24476996	18	+	27760321	HT29	viability after 22 days	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-1.2900167581800615	[247,193]	[88,109,114]	-7	hSpCas9	negative selection	4992259
24476989	24477011	18	-	27760321	HT29	viability after 22 days	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.24690076694325397	[322,251]	[189,336,315]	-3	hSpCas9	negative selection	4992260
24460863	24460885	18	-	27760321	HT29	viability after 19 days	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.6672514440703194	[44,34]	[25,7,174]	6	hSpCas9	negative selection	5075719
24476885	24476907	18	-	27760321	HT29	viability after 19 days	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	-0.055684715927870165	[103,80]	[76,159,66]	0	hSpCas9	negative selection	5075720
24476945	24476967	18	-	27760321	HT29	viability after 19 days	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-0.6758098755656063	[89,69]	[92,38,43]	-5	hSpCas9	negative selection	5075721
24476974	24476996	18	+	27760321	HT29	viability after 19 days	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-0.8009688946543698	[247,193]	[198,47,191]	-6	hSpCas9	negative selection	5075722
24476989	24477011	18	-	27760321	HT29	viability after 19 days	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.21377459292723358	[322,251]	[307,499,329]	2	hSpCas9	negative selection	5075723
24460863	24460885	18	-	27760321	HT29	viability after 16 days	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.04889248647697553	[44,34]	[17,52,64]	0	hSpCas9	negative selection	5159182
24476885	24476907	18	-	27760321	HT29	viability after 16 days	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	0.2482628481146616	[103,80]	[92,232,36]	2	hSpCas9	negative selection	5159183
24476945	24476967	18	-	27760321	HT29	viability after 16 days	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	0.5427390162587842	[89,69]	[216,100,81]	6	hSpCas9	negative selection	5159184
24476974	24476996	18	+	27760321	HT29	viability after 16 days	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-0.7396372746391902	[247,193]	[118,129,192]	-6	hSpCas9	negative selection	5159185
24476989	24477011	18	-	27760321	HT29	viability after 16 days	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.21907773385978618	[322,251]	[505,280,350]	2	hSpCas9	negative selection	5159186
24460863	24460885	18	-	27760321	HT29	viability after 13 days	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.5760149490577282	[44,34]	[3,16,69]	-6	hSpCas9	negative selection	5242645
24476885	24476907	18	-	27760321	HT29	viability after 13 days	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	-0.08555082051107954	[103,80]	[86,125,90]	-1	hSpCas9	negative selection	5242646
24476945	24476967	18	-	27760321	HT29	viability after 13 days	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	-0.4209195519992912	[89,69]	[92,47,66]	-5	hSpCas9	negative selection	5242647
24476974	24476996	18	+	27760321	HT29	viability after 13 days	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-1.3604006642815272	[247,193]	[77,161,61]	-8	hSpCas9	negative selection	5242648
24476989	24477011	18	-	27760321	HT29	viability after 13 days	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.3733445807256624	[322,251]	[164,373,234]	-4	hSpCas9	negative selection	5242649
24460863	24460885	18	-	27760321	HT29	viability after 10 days	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	1.1827961605673372	[44,34]	[93,20,219]	9	hSpCas9	negative selection	5326108
24476885	24476907	18	-	27760321	HT29	viability after 10 days	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	-0.3340354430191317	[103,80]	[165,21,84]	-4	hSpCas9	negative selection	5326109
24476945	24476967	18	-	27760321	HT29	viability after 10 days	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	0.024540500798395648	[89,69]	[72,59,168]	0	hSpCas9	negative selection	5326110
24476974	24476996	18	+	27760321	HT29	viability after 10 days	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-0.7311157213166957	[247,193]	[106,177,212]	-7	hSpCas9	negative selection	5326111
24476989	24477011	18	-	27760321	HT29	viability after 10 days	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.09254363825411194	[322,251]	[302,413,295]	-1	hSpCas9	negative selection	5326112
24460863	24460885	18	-	27760321	MOLM13	viability	ATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-4.670847782380083	[44,44]	[0,0]	-9	hSpCas9	negative selection	5409571
24476885	24476907	18	-	27760321	MOLM13	viability	ACCATTCCGAAAAAAATCCAGG	HRH4	ENSG00000134489	-0.9994476726564772	[129,103]	[14,47]	-5	hSpCas9	negative selection	5409572
24476945	24476967	18	-	27760321	MOLM13	viability	AATAAGCGACTAAGATGACTGG	HRH4	ENSG00000134489	2.2525280156733287	[125,89]	[228,336]	9	hSpCas9	negative selection	5409573
24476974	24476996	18	+	27760321	MOLM13	viability	GAATATTTATTGGAGCCTGTGG	HRH4	ENSG00000134489	-0.8081063632325591	[250,247]	[78,81]	-5	hSpCas9	negative selection	5409574
24476989	24477011	18	-	27760321	MOLM13	viability	GAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	1.0788924875731396	[353,322]	[547,279]	7	hSpCas9	negative selection	5409575
24460833	24460856	18	+	27661255	K562	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	-0.17816512424247166	[1098,1027]	[795,713]	-5	dCas9-KRAB	negative selection	5485542
24460900	24460923	18	+	27661255	K562	viability	GCCATCTCTGACTTCTTTGTGGG	HRH4	ENSG00000134489	-0.04442244617295943	[204,313]	[192,204]	-2	dCas9-KRAB	negative selection	5485543
24461065	24461088	18	+	27661255	K562	viability	GGGGCTATATGGCACTGTAAGGG	HRH4	ENSG00000134489	0.304209601655564	[1289,1717]	[1606,1363]	8	dCas9-KRAB	negative selection	5485544
24468812	24468835	18	+	27260156	BXPC3	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.48443969890096034	[327]	[426,363,625,518]	8	hSpCas9	negative selection	5548242
24468814	24468837	18	-	27260156	BXPC3	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.027609644120086374	[250]	[307,179,204,389]	0	hSpCas9	negative selection	5548243
24460863	24460886	18	-	27260156	BXPC3	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.13460548080349377	[158]	[138,148,178,137]	-3	hSpCas9	negative selection	5548244
24477072	24477095	18	+	27260156	BXPC3	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.028677066710100674	[595]	[590,716,524,598]	0	hSpCas9	negative selection	5612502
24477464	24477487	18	-	27260156	BXPC3	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.08468135032486696	[345]	[328,372,360,487]	1	hSpCas9	negative selection	5612503
24460732	24460755	18	-	27260156	BXPC3	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.0988896414914664	[964]	[867,772,1050,1110]	-2	hSpCas9	negative selection	5612504
24468812	24468835	18	+	27260156	A673	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.0920116067481388	[327]	[395,444,368,467]	2	hSpCas9	negative selection	5669493
24468814	24468837	18	-	27260156	A673	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.001699072405489721	[250]	[316,284,269,335]	0	hSpCas9	negative selection	5669494
24460863	24460886	18	-	27260156	A673	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.13276331381521245	[158]	[191,193,123,188]	-3	hSpCas9	negative selection	5669495
24477072	24477095	18	+	27260156	A673	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.007985871079730755	[595]	[708,679,664,796]	0	hSpCas9	negative selection	5733753
24477464	24477487	18	-	27260156	A673	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.030552278860351778	[345]	[394,460,459,372]	0	hSpCas9	negative selection	5733754
24460732	24460755	18	-	27260156	A673	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.3838582663028667	[964]	[1009,824,717,1021]	-7	hSpCas9	negative selection	5733755
24468812	24468835	18	+	27260156	A375	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.36565649722060084	[327]	[509,397,572,479]	5	hSpCas9	negative selection	5790744
24468814	24468837	18	-	27260156	A375	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.10892871908126622	[250]	[462,436,191,202]	1	hSpCas9	negative selection	5790745
24460863	24460886	18	-	27260156	A375	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.38946256173793325	[158]	[199,339,245,203]	5	hSpCas9	negative selection	5790746
24477072	24477095	18	+	27260156	A375	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.018655968360810016	[595]	[667,911,637,572]	0	hSpCas9	negative selection	5855004
24477464	24477487	18	-	27260156	A375	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.3687181490559054	[345]	[443,766,637,296]	5	hSpCas9	negative selection	5855005
24460732	24460755	18	-	27260156	A375	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.050712724861546876	[964]	[1318,939,884,1174]	0	hSpCas9	negative selection	5855006
24468812	24468835	18	+	27260156	COLO741	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.6831159974445539	[327]	[742,551,723]	9	hSpCas9	negative selection	5911995
24468814	24468837	18	-	27260156	COLO741	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.1571973566015189	[250]	[370,369,333]	3	hSpCas9	negative selection	5911996
24460863	24460886	18	-	27260156	COLO741	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.015806482647913178	[158]	[318,126,180]	0	hSpCas9	negative selection	5911997
24477072	24477095	18	+	27260156	COLO741	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.07534154740784721	[595]	[836,753,594]	-2	hSpCas9	negative selection	5976255
24477464	24477487	18	-	27260156	COLO741	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	-0.10193897276274566	[345]	[473,395,372]	-2	hSpCas9	negative selection	5976256
24460732	24460755	18	-	27260156	COLO741	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.17326230822589606	[964]	[917,1315,1033]	-4	hSpCas9	negative selection	5976257
24468812	24468835	18	+	27260156	CAL120	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.11809088332562512	[327]	[457,485,387]	1	hSpCas9	negative selection	6033246
24468814	24468837	18	-	27260156	CAL120	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.1382120819010929	[250]	[297,314,409]	2	hSpCas9	negative selection	6033247
24460863	24460886	18	-	27260156	CAL120	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.1333752341246397	[158]	[284,91,282]	2	hSpCas9	negative selection	6033248
24477072	24477095	18	+	27260156	CAL120	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.19936803871001635	[595]	[1021,930,630]	3	hSpCas9	negative selection	6097506
24477464	24477487	18	-	27260156	CAL120	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.34273340688474174	[345]	[723,472,468]	5	hSpCas9	negative selection	6097507
24460732	24460755	18	-	27260156	CAL120	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	0.18144079908977928	[964]	[1549,1533,1034]	2	hSpCas9	negative selection	6097508
24468812	24468835	18	+	27260156	CADOES1	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5952981922398903	[327]	[434,473,590,338]	8	hSpCas9	negative selection	6154497
24468814	24468837	18	-	27260156	CADOES1	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.15597566191187662	[250]	[246,159,243,185]	-3	hSpCas9	negative selection	6154498
24460863	24460886	18	-	27260156	CADOES1	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.6448575473847592	[158]	[245,184,306,184]	9	hSpCas9	negative selection	6154499
24477072	24477095	18	+	27260156	CADOES1	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.15528695493147682	[595]	[580,423,503,480]	-3	hSpCas9	negative selection	6218757
24477464	24477487	18	-	27260156	CADOES1	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.16554950201113638	[345]	[442,236,331,433]	3	hSpCas9	negative selection	6218758
24460732	24460755	18	-	27260156	CADOES1	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	0.0007481478581314871	[964]	[753,810,721,1320]	0	hSpCas9	negative selection	6218759
24468812	24468835	18	+	27260156	EWS502	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5539686102639887	[327]	[612,316,509,599]	8	hSpCas9	negative selection	6275748
24468814	24468837	18	-	27260156	EWS502	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.12088258982498878	[250]	[258,282,183,246]	-2	hSpCas9	negative selection	6275749
24460863	24460886	18	-	27260156	EWS502	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.22440107203645732	[158]	[235,123,177,249]	4	hSpCas9	negative selection	6275750
24477072	24477095	18	+	27260156	EWS502	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.05925600687749816	[595]	[564,563,629,673]	-1	hSpCas9	negative selection	6340008
24477464	24477487	18	-	27260156	EWS502	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.22148833008156285	[345]	[384,469,442,411]	4	hSpCas9	negative selection	6340009
24460732	24460755	18	-	27260156	EWS502	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.07698489982863133	[964]	[1001,855,980,1038]	-1	hSpCas9	negative selection	6340010
24468812	24468835	18	+	27260156	EW8	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.4628205396376823	[327]	[366,604,271,237]	8	hSpCas9	negative selection	6396999
24468814	24468837	18	-	27260156	EW8	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.24075001490006642	[250]	[428,100,299,140]	4	hSpCas9	negative selection	6397000
24460863	24460886	18	-	27260156	EW8	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.6613714705150606	[158]	[66,111,40,110]	-8	hSpCas9	negative selection	6397001
24477072	24477095	18	+	27260156	EW8	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.2993368307843493	[595]	[640,774,386,613]	5	hSpCas9	negative selection	6461259
24477464	24477487	18	-	27260156	EW8	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.11034132456965617	[345]	[311,382,275,244]	2	hSpCas9	negative selection	6461260
24460732	24460755	18	-	27260156	EW8	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.10825954436538943	[964]	[857,706,471,919]	-2	hSpCas9	negative selection	6461261
24468812	24468835	18	+	27260156	CORL105	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.6229034955058199	[327]	[779,415,690,503]	9	hSpCas9	negative selection	6518250
24468814	24468837	18	-	27260156	CORL105	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.3420402605356522	[250]	[349,343,426,376]	6	hSpCas9	negative selection	6518251
24460863	24460886	18	-	27260156	CORL105	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.02006633941130298	[158]	[165,141,244,190]	0	hSpCas9	negative selection	6518252
24477072	24477095	18	+	27260156	CORL105	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.0346394518507363	[595]	[642,584,921,612]	0	hSpCas9	negative selection	6582510
24477464	24477487	18	-	27260156	CORL105	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	-0.18145498673312044	[345]	[416,356,338,314]	-3	hSpCas9	negative selection	6582511
24460732	24460755	18	-	27260156	CORL105	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.10073905146245687	[964]	[1215,947,1174,901]	-2	hSpCas9	negative selection	6582512
24468812	24468835	18	+	27260156	HS294T	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.36457745779321304	[327]	[171,100,216,163]	5	hSpCas9	negative selection	6639501
24468814	24468837	18	-	27260156	HS294T	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.37191566499019024	[250]	[140,81,117,167]	5	hSpCas9	negative selection	6639502
24460863	24460886	18	-	27260156	HS294T	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.3222749785687673	[158]	[64,32,30,69]	-4	hSpCas9	negative selection	6639503
24477072	24477095	18	+	27260156	HS294T	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.03090192087700372	[595]	[235,171,274,264]	0	hSpCas9	negative selection	6703761
24477464	24477487	18	-	27260156	HS294T	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.43616274273645017	[345]	[132,149,230,221]	6	hSpCas9	negative selection	6703762
24460732	24460755	18	-	27260156	HS294T	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.13016710782533258	[964]	[327,398,322,305]	-2	hSpCas9	negative selection	6703763
24468812	24468835	18	+	27260156	HCC44	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.07089765771695172	[327]	[348,432,479,301]	1	hSpCas9	negative selection	6760752
24468814	24468837	18	-	27260156	HCC44	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.39885270735017153	[250]	[245,410,520,325]	6	hSpCas9	negative selection	6760753
24460863	24460886	18	-	27260156	HCC44	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.1956495569686323	[158]	[191,130,162,148]	-3	hSpCas9	negative selection	6760754
24477072	24477095	18	+	27260156	HCC44	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.0708312707985922	[595]	[774,472,566,765]	-1	hSpCas9	negative selection	6825012
24477464	24477487	18	-	27260156	HCC44	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.25259981499373313	[345]	[503,382,473,514]	4	hSpCas9	negative selection	6825013
24460732	24460755	18	-	27260156	HCC44	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.04575397051590735	[964]	[1006,874,1071,1282]	0	hSpCas9	negative selection	6825014
24468812	24468835	18	+	27260156	G402	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.05298490305266501	[327]	[457,616,290,315]	0	hSpCas9	negative selection	6882003
24468814	24468837	18	-	27260156	G402	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.5375329574952274	[250]	[338,703,239,490]	6	hSpCas9	negative selection	6882004
24460863	24460886	18	-	27260156	G402	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.4150042800074494	[158]	[375,236,105,326]	5	hSpCas9	negative selection	6882005
24477072	24477095	18	+	27260156	G402	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.1584907180408734	[595]	[1173,643,652,814]	2	hSpCas9	negative selection	6946263
24477464	24477487	18	-	27260156	G402	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.4213740319739696	[345]	[783,510,685,318]	5	hSpCas9	negative selection	6946264
24460732	24460755	18	-	27260156	G402	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.08541567271700612	[964]	[1065,769,1381,1186]	-1	hSpCas9	negative selection	6946265
24468812	24468835	18	+	27260156	L33	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.16277795108870657	[327]	[294,191,217,359]	3	hSpCas9	negative selection	7003254
24468814	24468837	18	-	27260156	L33	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.41879291409711283	[250]	[303,102,257,376]	8	hSpCas9	negative selection	7003255
24460863	24460886	18	-	27260156	L33	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.10800781315336838	[158]	[131,86,118,152]	2	hSpCas9	negative selection	7003256
24477072	24477095	18	+	27260156	L33	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.06040859953516675	[595]	[495,229,460,697]	1	hSpCas9	negative selection	7067514
24477464	24477487	18	-	27260156	L33	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.04644219541038702	[345]	[332,117,275,369]	1	hSpCas9	negative selection	7067515
24460732	24460755	18	-	27260156	L33	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.1142658375492227	[964]	[891,498,380,848]	-3	hSpCas9	negative selection	7067516
24468812	24468835	18	+	27260156	K562	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.658826162519913	[327]	[362,526,624,331]	8	hSpCas9	negative selection	7124505
24468814	24468837	18	-	27260156	K562	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.019130454980524347	[250]	[351,194,84,251]	0	hSpCas9	negative selection	7124506
24460863	24460886	18	-	27260156	K562	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.8940604378031116	[158]	[192,375,168,304]	9	hSpCas9	negative selection	7124507
24477072	24477095	18	+	27260156	K562	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.21199478749242934	[595]	[612,761,526,559]	2	hSpCas9	negative selection	7188765
24477464	24477487	18	-	27260156	K562	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	1.0009807057556328	[345]	[987,640,390,482]	9	hSpCas9	negative selection	7188766
24460732	24460755	18	-	27260156	K562	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	0.11556212370046492	[964]	[1057,806,1064,796]	1	hSpCas9	negative selection	7188767
24468812	24468835	18	+	27260156	HT29	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5321254618963381	[327]	[704,559,544,508]	8	hSpCas9	negative selection	7245756
24468814	24468837	18	-	27260156	HT29	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.20802395180757272	[250]	[392,418,358,256]	4	hSpCas9	negative selection	7245757
24460863	24460886	18	-	27260156	HT29	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.03830711359541383	[158]	[235,189,209,126]	-1	hSpCas9	negative selection	7245758
24477072	24477095	18	+	27260156	HT29	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.19239124543319258	[595]	[771,592,748,447]	-4	hSpCas9	negative selection	7310016
24477464	24477487	18	-	27260156	HT29	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.2998177361532891	[345]	[412,447,546,630]	6	hSpCas9	negative selection	7310017
24460732	24460755	18	-	27260156	HT29	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.2540768298762194	[964]	[953,1051,833,1078]	-5	hSpCas9	negative selection	7310018
24468812	24468835	18	+	27260156	MHHES1	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.7164517022187858	[327]	[474,664,494,736]	9	hSpCas9	negative selection	7367007
24468814	24468837	18	-	27260156	MHHES1	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.2589190296592294	[250]	[252,326,249,142]	-5	hSpCas9	negative selection	7367008
24460863	24460886	18	-	27260156	MHHES1	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.2107280786354353	[158]	[54,132,153,238]	-4	hSpCas9	negative selection	7367009
24477072	24477095	18	+	27260156	MHHES1	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.06283271751892788	[595]	[1039,701,561,369]	-1	hSpCas9	negative selection	7431267
24477464	24477487	18	-	27260156	MHHES1	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.16974584566638973	[345]	[419,431,331,532]	3	hSpCas9	negative selection	7431268
24460732	24460755	18	-	27260156	MHHES1	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.30307895712006083	[964]	[1059,1001,859,665]	-5	hSpCas9	negative selection	7431269
24468812	24468835	18	+	27260156	MEWO	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.41395690185238126	[327]	[463,435,336]	8	hSpCas9	negative selection	7488258
24468814	24468837	18	-	27260156	MEWO	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.09259792390004318	[250]	[205,194,256]	-2	hSpCas9	negative selection	7488259
24460863	24460886	18	-	27260156	MEWO	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.022170219354763265	[158]	[120,215,109]	0	hSpCas9	negative selection	7488260
24477072	24477095	18	+	27260156	MEWO	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.1273100862944876	[595]	[731,566,551]	3	hSpCas9	negative selection	7552518
24477464	24477487	18	-	27260156	MEWO	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.1966969093167536	[345]	[484,364,284]	4	hSpCas9	negative selection	7552519
24460732	24460755	18	-	27260156	MEWO	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.30135440669643976	[964]	[629,698,848]	-6	hSpCas9	negative selection	7552520
24468812	24468835	18	+	27260156	LNCAPCLONEFGC	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5703156882851739	[327]	[468,349,488,468]	8	hSpCas9	negative selection	7609509
24468814	24468837	18	-	27260156	LNCAPCLONEFGC	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.009717169470207843	[250]	[271,196,257,181]	0	hSpCas9	negative selection	7609510
24460863	24460886	18	-	27260156	LNCAPCLONEFGC	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.1626706083199001	[158]	[65,147,124,174]	-3	hSpCas9	negative selection	7609511
24477072	24477095	18	+	27260156	LNCAPCLONEFGC	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.0018192712181275827	[595]	[524,560,644,439]	0	hSpCas9	negative selection	7673769
24477464	24477487	18	-	27260156	LNCAPCLONEFGC	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.18842566300489694	[345]	[372,310,416,338]	3	hSpCas9	negative selection	7673770
24460732	24460755	18	-	27260156	LNCAPCLONEFGC	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.10876096070925156	[964]	[850,648,870,889]	-2	hSpCas9	negative selection	7673771
24468812	24468835	18	+	27260156	PANC0327	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.036253925116884855	[327]	[277,245,351,264]	0	hSpCas9	negative selection	7730760
24468814	24468837	18	-	27260156	PANC0327	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.11937838553210511	[250]	[341,221,154,110]	-2	hSpCas9	negative selection	7730761
24460863	24460886	18	-	27260156	PANC0327	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.521002853562095	[158]	[136,104,85,67]	-6	hSpCas9	negative selection	7730762
24477072	24477095	18	+	27260156	PANC0327	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.2341802791351955	[595]	[625,496,550,832]	3	hSpCas9	negative selection	7795020
24477464	24477487	18	-	27260156	PANC0327	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.27775037061915875	[345]	[293,308,378,509]	4	hSpCas9	negative selection	7795021
24460732	24460755	18	-	27260156	PANC0327	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.4319411242858525	[964]	[697,456,815,598]	-6	hSpCas9	negative selection	7795022
24468812	24468835	18	+	27260156	NCIH2009	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.3808193079786405	[327]	[658,618,522]	5	hSpCas9	negative selection	7852011
24468814	24468837	18	-	27260156	NCIH2009	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.743351116821967	[250]	[492,510,738]	8	hSpCas9	negative selection	7852012
24460863	24460886	18	-	27260156	NCIH2009	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.17148681847132652	[158]	[324,245,193]	2	hSpCas9	negative selection	7852013
24477072	24477095	18	+	27260156	NCIH2009	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.211557550741038	[595]	[832,700,644]	-3	hSpCas9	negative selection	7916271
24477464	24477487	18	-	27260156	NCIH2009	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.6255584335454547	[345]	[700,763,761]	8	hSpCas9	negative selection	7916272
24460732	24460755	18	-	27260156	NCIH2009	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.12933219355122316	[964]	[1289,1132,1285]	-2	hSpCas9	negative selection	7916273
24468812	24468835	18	+	27260156	NCIH1373	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.9153511913782789	[327]	[972,307,604,259]	8	hSpCas9	negative selection	7973262
24468814	24468837	18	-	27260156	NCIH1373	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	1.058648326147106	[250]	[550,815,403,141]	9	hSpCas9	negative selection	7973263
24460863	24460886	18	-	27260156	NCIH1373	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.41369594879107807	[158]	[190,117,43,51]	-4	hSpCas9	negative selection	7973264
24477072	24477095	18	+	27260156	NCIH1373	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.4073534536724705	[595]	[973,640,961,264]	4	hSpCas9	negative selection	8037522
24477464	24477487	18	-	27260156	NCIH1373	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.6995848256554416	[345]	[401,592,1111,91]	7	hSpCas9	negative selection	8037523
24460732	24460755	18	-	27260156	NCIH1373	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	0.049699374091017434	[964]	[1460,790,1139,307]	0	hSpCas9	negative selection	8037524
24468812	24468835	18	+	27260156	PATU8902	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.8644884761489225	[327]	[1056,1031,496,816]	8	hSpCas9	negative selection	8094513
24468814	24468837	18	-	27260156	PATU8902	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.7416152153803407	[250]	[558,449,656,656]	7	hSpCas9	negative selection	8094514
24460863	24460886	18	-	27260156	PATU8902	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.32040569913662975	[158]	[313,171,124,565]	3	hSpCas9	negative selection	8094515
24477072	24477095	18	+	27260156	PATU8902	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.3165003908887513	[595]	[482,703,1123,1901]	3	hSpCas9	negative selection	8158773
24477464	24477487	18	-	27260156	PATU8902	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.5264971787680156	[345]	[793,583,648,761]	5	hSpCas9	negative selection	8158774
24460732	24460755	18	-	27260156	PATU8902	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.3593765314858868	[964]	[940,630,859,1900]	-4	hSpCas9	negative selection	8158775
24468812	24468835	18	+	27260156	PANC1	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.5119442162740206	[327]	[316,297,498,457]	8	hSpCas9	negative selection	8215764
24468814	24468837	18	-	27260156	PANC1	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.6906934630611922	[250]	[358,357,430,255]	9	hSpCas9	negative selection	8215765
24460863	24460886	18	-	27260156	PANC1	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.12967650566098365	[158]	[148,175,98,88]	-2	hSpCas9	negative selection	8215766
24477072	24477095	18	+	27260156	PANC1	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.057584495652187095	[595]	[422,773,487,494]	0	hSpCas9	negative selection	8280024
24477464	24477487	18	-	27260156	PANC1	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.19637444637978707	[345]	[473,256,299,309]	3	hSpCas9	negative selection	8280025
24460732	24460755	18	-	27260156	PANC1	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	0.0023155318334326935	[964]	[979,836,990,545]	0	hSpCas9	negative selection	8280026
24468812	24468835	18	+	27260156	PANC0813	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.8016485709340233	[327]	[585,773,677,640]	9	hSpCas9	negative selection	8337015
24468814	24468837	18	-	27260156	PANC0813	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.2224346966329147	[250]	[259,192,540,372]	3	hSpCas9	negative selection	8337016
24460863	24460886	18	-	27260156	PANC0813	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.6080970465518125	[158]	[226,108,105,60]	-7	hSpCas9	negative selection	8337017
24477072	24477095	18	+	27260156	PANC0813	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.7533040737256785	[595]	[485,331,394,451]	-8	hSpCas9	negative selection	8401275
24477464	24477487	18	-	27260156	PANC0813	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.008396017090819441	[345]	[469,453,432,289]	0	hSpCas9	negative selection	8401276
24460732	24460755	18	-	27260156	PANC0813	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.8937245243838853	[964]	[739,421,579,703]	-8	hSpCas9	negative selection	8401277
24468812	24468835	18	+	27260156	RDES	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.3382738673674064	[327]	[339,394,542,688]	5	hSpCas9	negative selection	8458266
24468814	24468837	18	-	27260156	RDES	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.09566404494818381	[250]	[225,303,348,375]	1	hSpCas9	negative selection	8458267
24460863	24460886	18	-	27260156	RDES	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.19209260380601512	[158]	[191,230,157,253]	3	hSpCas9	negative selection	8458268
24477072	24477095	18	+	27260156	RDES	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.32153050954016993	[595]	[408,492,545,804]	-5	hSpCas9	negative selection	8522526
24477464	24477487	18	-	27260156	RDES	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.3102567736027949	[345]	[386,443,568,606]	5	hSpCas9	negative selection	8522527
24460732	24460755	18	-	27260156	RDES	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.25436223302040917	[964]	[680,941,944,1224]	-4	hSpCas9	negative selection	8522528
24468812	24468835	18	+	27260156	PC3	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	-0.2150529997699291	[327]	[112,380,557,228]	-5	hSpCas9	negative selection	8579517
24468814	24468837	18	-	27260156	PC3	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.2123690329740897	[250]	[127,436,525,196]	5	hSpCas9	negative selection	8579518
24460863	24460886	18	-	27260156	PC3	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.3669447782395867	[158]	[63,73,317,130]	-7	hSpCas9	negative selection	8579519
24477072	24477095	18	+	27260156	PC3	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.11153363124251675	[595]	[387,756,1065,560]	2	hSpCas9	negative selection	8643777
24477464	24477487	18	-	27260156	PC3	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.12054363765364962	[345]	[201,265,920,374]	2	hSpCas9	negative selection	8643778
24460732	24460755	18	-	27260156	PC3	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.1145095811857113	[964]	[738,848,1187,847]	-3	hSpCas9	negative selection	8643779
24468812	24468835	18	+	27260156	PATU8988T	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.49948830684058054	[327]	[354,553,299,607]	8	hSpCas9	negative selection	8700768
24468814	24468837	18	-	27260156	PATU8988T	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.4237752042538767	[250]	[276,190,111,141]	-6	hSpCas9	negative selection	8700769
24460863	24460886	18	-	27260156	PATU8988T	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.2615580014968333	[158]	[282,230,44,183]	4	hSpCas9	negative selection	8700770
24477072	24477095	18	+	27260156	PATU8988T	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.31352476633797155	[595]	[558,490,469,324]	-5	hSpCas9	negative selection	8765028
24477464	24477487	18	-	27260156	PATU8988T	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.08855140803302702	[345]	[329,471,275,355]	1	hSpCas9	negative selection	8765029
24460732	24460755	18	-	27260156	PATU8988T	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.10618535113112593	[964]	[912,698,910,930]	-2	hSpCas9	negative selection	8765030
24468812	24468835	18	+	27260156	T47D	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.35207922911813705	[327]	[434,458,442,620]	7	hSpCas9	negative selection	8822019
24468814	24468837	18	-	27260156	T47D	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.07818784332296369	[250]	[352,319,308,249]	1	hSpCas9	negative selection	8822020
24460863	24460886	18	-	27260156	T47D	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.08533000730336293	[158]	[221,149,153,174]	-2	hSpCas9	negative selection	8822021
24477072	24477095	18	+	27260156	T47D	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.07844905676087904	[595]	[744,647,720,828]	1	hSpCas9	negative selection	8886279
24477464	24477487	18	-	27260156	T47D	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.12586915235477963	[345]	[542,369,435,415]	2	hSpCas9	negative selection	8886280
24460732	24460755	18	-	27260156	T47D	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.13191788773183388	[964]	[1097,953,991,1067]	-3	hSpCas9	negative selection	8886281
24468812	24468835	18	+	27260156	SU8686	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.4731490468117753	[327]	[461,427,396,527]	7	hSpCas9	negative selection	8943270
24468814	24468837	18	-	27260156	SU8686	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.42575524101340895	[250]	[270,276,427,383]	7	hSpCas9	negative selection	8943271
24460863	24460886	18	-	27260156	SU8686	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.146139651204241	[158]	[161,118,112,180]	-3	hSpCas9	negative selection	8943272
24477072	24477095	18	+	27260156	SU8686	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.12024531439146458	[595]	[484,469,763,936]	2	hSpCas9	negative selection	9007530
24477464	24477487	18	-	27260156	SU8686	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.09628176112642389	[345]	[409,340,367,338]	1	hSpCas9	negative selection	9007531
24460732	24460755	18	-	27260156	SU8686	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.028527089807982575	[964]	[936,670,1076,1129]	0	hSpCas9	negative selection	9007532
24468812	24468835	18	+	27260156	SKES1	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.26912113185017195	[327]	[468,315,426,364]	6	hSpCas9	negative selection	9064521
24468814	24468837	18	-	27260156	SKES1	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	-0.1975791517606993	[250]	[159,349,237,139]	-4	hSpCas9	negative selection	9064522
24460863	24460886	18	-	27260156	SKES1	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.16623439670270468	[158]	[139,188,130,112]	-4	hSpCas9	negative selection	9064523
24477072	24477095	18	+	27260156	SKES1	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.11086866906103154	[595]	[444,693,535,526]	-2	hSpCas9	negative selection	9128781
24477464	24477487	18	-	27260156	SKES1	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	-0.0661868468248169	[345]	[414,346,328,247]	-1	hSpCas9	negative selection	9128782
24460732	24460755	18	-	27260156	SKES1	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.14728994286923558	[964]	[1073,770,870,778]	-3	hSpCas9	negative selection	9128783
24468812	24468835	18	+	27260156	TOV112D	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.29129210600121214	[327]	[416,731,180,360]	5	hSpCas9	negative selection	9185772
24468814	24468837	18	-	27260156	TOV112D	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.35437668168298664	[250]	[369,423,294,227]	6	hSpCas9	negative selection	9185773
24460863	24460886	18	-	27260156	TOV112D	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.3934724942161725	[158]	[135,95,134,112]	-7	hSpCas9	negative selection	9185774
24477072	24477095	18	+	27260156	TOV112D	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.008736299707613582	[595]	[724,643,547,507]	0	hSpCas9	negative selection	9250032
24477464	24477487	18	-	27260156	TOV112D	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.4870163068714568	[345]	[433,485,507,508]	8	hSpCas9	negative selection	9250033
24460732	24460755	18	-	27260156	TOV112D	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.11810610307850711	[964]	[1099,743,908,791]	-2	hSpCas9	negative selection	9250034
24468812	24468835	18	+	27260156	TC71	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.13351519059796507	[327]	[282,389,361,518]	3	hSpCas9	negative selection	9307023
24468814	24468837	18	-	27260156	TC71	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.11007061238536897	[250]	[246,320,184,420]	3	hSpCas9	negative selection	9307024
24460863	24460886	18	-	27260156	TC71	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	-0.1781041820152942	[158]	[156,138,187,114]	-5	hSpCas9	negative selection	9307025
24477072	24477095	18	+	27260156	TC71	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	0.06011667832167078	[595]	[567,617,676,811]	1	hSpCas9	negative selection	9371283
24477464	24477487	18	-	27260156	TC71	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	-0.04647437051239883	[345]	[319,292,282,555]	-1	hSpCas9	negative selection	9371284
24460732	24460755	18	-	27260156	TC71	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.16732754163807284	[964]	[782,997,938,969]	-4	hSpCas9	negative selection	9371285
24468812	24468835	18	+	27260156	TC32	viability	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.4075107552176206	[327]	[475,262,469,461]	7	hSpCas9	negative selection	9428274
24468814	24468837	18	-	27260156	TC32	viability	TCCCATTCGAACAGCGTGTGAGG	HRH4	ENSG00000134489	0.1575722546995756	[250]	[208,158,448,301]	3	hSpCas9	negative selection	9428275
24460863	24460886	18	-	27260156	TC32	viability	AATAACTACTTCGATGTCTAAGG	HRH4	ENSG00000134489	0.10997259912170865	[158]	[231,92,168,158]	2	hSpCas9	negative selection	9428276
24477072	24477095	18	+	27260156	TC32	viability	TCAGAGGTAGACTATCTTCAAGG	HRH4	ENSG00000134489	-0.30983360073150074	[595]	[449,295,686,447]	-5	hSpCas9	negative selection	9492534
24477464	24477487	18	-	27260156	TC32	viability	TGAAAGCGCTTGTGACACAATGG	HRH4	ENSG00000134489	0.37037424278626013	[345]	[331,238,729,495]	6	hSpCas9	negative selection	9492535
24460732	24460755	18	-	27260156	TC32	viability	TTGATTGTGCTATTAGTATCTGG	HRH4	ENSG00000134489	-0.18279533203903453	[964]	[658,502,1290,920]	-3	hSpCas9	negative selection	9492536
24468802	24468825	18	-	27869803	HPAFII	viability after 27 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.18031640177361757	[310]	[127,232,NaN]	1	hSpCas9	negative selection	9564271
24468812	24468835	18	+	27869803	HPAFII	viability after 27 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.3796671659994388	[331]	[273,187,NaN]	3	hSpCas9	negative selection	9564272
24476867	24476890	18	+	27869803	HPAFII	viability after 27 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.6679634090996445	[137]	[105,122,NaN]	5	hSpCas9	negative selection	9564273
24476911	24476934	18	-	27869803	HPAFII	viability after 27 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.3469471243175718	[362]	[341,159,NaN]	2	hSpCas9	negative selection	9564274
24477264	24477287	18	+	27869803	HPAFII	viability after 27 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	1.4924853027556062	[168]	[399,124,NaN]	9	hSpCas9	negative selection	9564275
24468802	24468825	18	-	27869803	HPAFII	viability after 15 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.5417866912172027	[310]	[620,402,NaN]	6	hSpCas9	negative selection	9646720
24468812	24468835	18	+	27869803	HPAFII	viability after 15 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.2779668757701094	[331]	[542,363,NaN]	3	hSpCas9	negative selection	9646721
24476867	24476890	18	+	27869803	HPAFII	viability after 15 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.26907964800151807	[137]	[240,139,NaN]	3	hSpCas9	negative selection	9646722
24476911	24476934	18	-	27869803	HPAFII	viability after 15 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.3396278241649734	[362]	[616,416,NaN]	4	hSpCas9	negative selection	9646723
24477264	24477287	18	+	27869803	HPAFII	viability after 15 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.5548490277617585	[168]	[436,160,NaN]	6	hSpCas9	negative selection	9646724
24468802	24468825	18	-	27869803	ASPC1	viability after 36 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.07784514126964392	[1203]	[509,534,206]	-1	hSpCas9	negative selection	9729169
24468812	24468835	18	+	27869803	ASPC1	viability after 36 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.2886654828858163	[893]	[285,423,409]	3	hSpCas9	negative selection	9729170
24476867	24476890	18	+	27869803	ASPC1	viability after 36 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	-0.5321103345666972	[394]	[113,135,48]	-5	hSpCas9	negative selection	9729171
24476911	24476934	18	-	27869803	ASPC1	viability after 36 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.2918677789192916	[836]	[148,604,303]	3	hSpCas9	negative selection	9729172
24477264	24477287	18	+	27869803	ASPC1	viability after 36 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.05413223655345478	[417]	[72,255,121]	0	hSpCas9	negative selection	9729173
24468802	24468825	18	-	27869803	PATU8988S	viability after 35 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-1.4377014472293392	[957]	[112,171,NaN]	-8	hSpCas9	negative selection	9811618
24468812	24468835	18	+	27869803	PATU8988S	viability after 35 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.8494916349458183	[757]	[585,513,NaN]	8	hSpCas9	negative selection	9811619
24476867	24476890	18	+	27869803	PATU8988S	viability after 35 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	-0.5561951515238367	[333]	[84,97,NaN]	-5	hSpCas9	negative selection	9811620
24476911	24476934	18	-	27869803	PATU8988S	viability after 35 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.28862759348417527	[779]	[118,395,NaN]	-3	hSpCas9	negative selection	9811621
24477264	24477287	18	+	27869803	PATU8988S	viability after 35 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.44158819334431637	[311]	[238,101,NaN]	5	hSpCas9	negative selection	9811622
24468802	24468825	18	-	27869803	PATU8988S	viability after 31 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	-0.8421675773462696	[957]	[209,216,NaN]	-7	hSpCas9	negative selection	9894067
24468812	24468835	18	+	27869803	PATU8988S	viability after 31 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	1.1324934519460932	[757]	[465,912,NaN]	9	hSpCas9	negative selection	9894068
24476867	24476890	18	+	27869803	PATU8988S	viability after 31 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.05665858907732613	[333]	[112,170,NaN]	0	hSpCas9	negative selection	9894069
24476911	24476934	18	-	27869803	PATU8988S	viability after 31 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.055651027786101315	[779]	[185,497,NaN]	0	hSpCas9	negative selection	9894070
24477264	24477287	18	+	27869803	PATU8988S	viability after 31 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	0.4901246925771472	[311]	[267,55,NaN]	6	hSpCas9	negative selection	9894071
24468802	24468825	18	-	27869803	HPAFII	viability after 35 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.3018183766464713	[310]	[115,281,NaN]	2	hSpCas9	negative selection	9976516
24468812	24468835	18	+	27869803	HPAFII	viability after 35 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.039170092404534285	[331]	[159,186,NaN]	0	hSpCas9	negative selection	9976517
24476867	24476890	18	+	27869803	HPAFII	viability after 35 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.22916764109873888	[137]	[95,65,NaN]	1	hSpCas9	negative selection	9976518
24476911	24476934	18	-	27869803	HPAFII	viability after 35 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	-0.05874599129942937	[362]	[222,123,NaN]	0	hSpCas9	negative selection	9976519
24477264	24477287	18	+	27869803	HPAFII	viability after 35 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	1.6494244829349451	[168]	[353,171,NaN]	9	hSpCas9	negative selection	9976520
24468802	24468825	18	-	27869803	HPAFII	viability after 31 days	AGCGTGTGAGGGATGTACAAAGG	HRH4	ENSG00000134489	0.12424473820990634	[310]	[94,293,NaN]	0	hSpCas9	negative selection	10058965
24468812	24468835	18	+	27869803	HPAFII	viability after 31 days	TCCCTCACACGCTGTTCGAATGG	HRH4	ENSG00000134489	0.4546640171533865	[331]	[251,258,NaN]	3	hSpCas9	negative selection	10058966
24476867	24476890	18	+	27869803	HPAFII	viability after 31 days	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.8721970568388248	[137]	[169,110,NaN]	6	hSpCas9	negative selection	10058967
24476911	24476934	18	-	27869803	HPAFII	viability after 31 days	CCAAGAATGATGTGATGGCAAGG	HRH4	ENSG00000134489	0.3575699012559759	[362]	[361,150,NaN]	2	hSpCas9	negative selection	10058968
24477264	24477287	18	+	27869803	HPAFII	viability after 31 days	ATGTTGAACTGCTTAGAGCCAGG	HRH4	ENSG00000134489	1.8282400915721073	[168]	[443,219,NaN]	9	hSpCas9	negative selection	10058969
24460833	24460856	18	+	28162770	P31FUJ	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	0.5972727941433091	[179]	[319]	6	hSpCas9	negative selection	10171190
24477253	24477276	18	-	28162770	P31FUJ	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.8291255447288235	[284]	[594]	8	hSpCas9	negative selection	10171191
24460901	24460924	18	-	28162770	P31FUJ	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.4076554088984812	[169]	[264]	4	hSpCas9	negative selection	10171192
24477041	24477064	18	+	28162770	P31FUJ	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.539103881638936	[823]	[1406]	6	hSpCas9	negative selection	10171193
24476867	24476890	18	+	28162770	P31FUJ	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.43516482306186366	[196]	[312]	5	hSpCas9	negative selection	10171194
24477025	24477048	18	-	28162770	P31FUJ	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.11046666149032625	[112]	[122]	-1	hSpCas9	negative selection	10171195
24476989	24477012	18	-	28162770	P31FUJ	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.3549616467809176	[685]	[1030]	4	hSpCas9	negative selection	10171196
24477011	24477034	18	+	28162770	P31FUJ	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.4995020123819646	[123]	[205]	5	hSpCas9	negative selection	10171197
24477051	24477074	18	-	28162770	P31FUJ	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.29624262418894665	[981]	[1416]	3	hSpCas9	negative selection	10171198
24477129	24477152	18	+	28162770	P31FUJ	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.5222457487352856	[332]	[561]	6	hSpCas9	negative selection	10171199
24460833	24460856	18	+	28162770	TF1	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	NaN	[NaN]	[564]	1	hSpCas9	negative selection	10340556
24477253	24477276	18	-	28162770	TF1	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	NaN	[NaN]	[369]	1	hSpCas9	negative selection	10340557
24460901	24460924	18	-	28162770	TF1	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10340558
24477041	24477064	18	+	28162770	TF1	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	NaN	[NaN]	[773]	1	hSpCas9	negative selection	10340559
24476867	24476890	18	+	28162770	TF1	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	NaN	[NaN]	[376]	1	hSpCas9	negative selection	10340560
24477025	24477048	18	-	28162770	TF1	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10340561
24476989	24477012	18	-	28162770	TF1	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	NaN	[NaN]	[571]	1	hSpCas9	negative selection	10340562
24477011	24477034	18	+	28162770	TF1	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10340563
24477051	24477074	18	-	28162770	TF1	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	NaN	[NaN]	[646]	1	hSpCas9	negative selection	10340564
24477129	24477152	18	+	28162770	TF1	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	NaN	[NaN]	[302]	1	hSpCas9	negative selection	10340565
24460833	24460856	18	+	28162770	SKM1	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.043980954006307	[61]	[225]	8	hSpCas9	negative selection	10509922
24477253	24477276	18	-	28162770	SKM1	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.0761186879587809	[65]	[122]	0	hSpCas9	negative selection	10509923
24460901	24460924	18	-	28162770	SKM1	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.44103270781178816	[44]	[107]	4	hSpCas9	negative selection	10509924
24477041	24477064	18	+	28162770	SKM1	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.5093778722099289	[212]	[535]	5	hSpCas9	negative selection	10509925
24476867	24476890	18	+	28162770	SKM1	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.6915256646562016	[68]	[196]	6	hSpCas9	negative selection	10509926
24477025	24477048	18	-	28162770	SKM1	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	0.9435330483409715	[29]	[101]	8	hSpCas9	negative selection	10509927
24476989	24477012	18	-	28162770	SKM1	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.012998923082919278	[124]	[218]	0	hSpCas9	negative selection	10509928
24477011	24477034	18	+	28162770	SKM1	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.798584712429872	[39]	[122]	7	hSpCas9	negative selection	10509929
24477051	24477074	18	-	28162770	SKM1	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.24773937326855533	[211]	[444]	2	hSpCas9	negative selection	10509930
24477129	24477152	18	+	28162770	SKM1	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.9977903272738211	[65]	[232]	8	hSpCas9	negative selection	10509931
24460833	24460856	18	+	28162770	SKM1	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.043980954006307	[61]	[225]	8	hSpCas9	negative selection	10679288
24477253	24477276	18	-	28162770	SKM1	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.0761186879587809	[65]	[122]	0	hSpCas9	negative selection	10679289
24460901	24460924	18	-	28162770	SKM1	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.44103270781178816	[44]	[107]	4	hSpCas9	negative selection	10679290
24477041	24477064	18	+	28162770	SKM1	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.5093778722099289	[212]	[535]	5	hSpCas9	negative selection	10679291
24476867	24476890	18	+	28162770	SKM1	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.6915256646562016	[68]	[196]	6	hSpCas9	negative selection	10679292
24477025	24477048	18	-	28162770	SKM1	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	0.9435330483409715	[29]	[101]	8	hSpCas9	negative selection	10679293
24476989	24477012	18	-	28162770	SKM1	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.012998923082919278	[124]	[218]	0	hSpCas9	negative selection	10679294
24477011	24477034	18	+	28162770	SKM1	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.798584712429872	[39]	[122]	7	hSpCas9	negative selection	10679295
24477051	24477074	18	-	28162770	SKM1	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.24773937326855533	[211]	[444]	2	hSpCas9	negative selection	10679296
24477129	24477152	18	+	28162770	SKM1	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.9977903272738211	[65]	[232]	8	hSpCas9	negative selection	10679297
24460833	24460856	18	+	28162770	PL21	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	-0.1283313262648142	[220]	[87]	-1	hSpCas9	negative selection	10848654
24477253	24477276	18	-	28162770	PL21	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	-0.27607522297981135	[280]	[100]	-2	hSpCas9	negative selection	10848655
24460901	24460924	18	-	28162770	PL21	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.3376431382392551	[179]	[98]	3	hSpCas9	negative selection	10848656
24477041	24477064	18	+	28162770	PL21	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.9634547397191433	[726]	[616]	7	hSpCas9	negative selection	10848657
24476867	24476890	18	+	28162770	PL21	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.1101074136268474	[280]	[131]	1	hSpCas9	negative selection	10848658
24477025	24477048	18	-	28162770	PL21	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.017765415854813726	[106]	[45]	0	hSpCas9	negative selection	10848659
24476989	24477012	18	-	28162770	PL21	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.18282013828929378	[418]	[206]	1	hSpCas9	negative selection	10848660
24477011	24477034	18	+	28162770	PL21	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	1.6196785060031047	[79]	[106]	9	hSpCas9	negative selection	10848661
24477051	24477074	18	-	28162770	PL21	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.4453796433792727	[706]	[418]	4	hSpCas9	negative selection	10848662
24477129	24477152	18	+	28162770	PL21	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	1.0074945365469246	[223]	[195]	8	hSpCas9	negative selection	10848663
24460833	24460856	18	+	28162770	P31FUJ	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	0.5972727941433091	[179]	[319]	6	hSpCas9	negative selection	11018020
24477253	24477276	18	-	28162770	P31FUJ	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.8291255447288235	[284]	[594]	8	hSpCas9	negative selection	11018021
24460901	24460924	18	-	28162770	P31FUJ	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.4076554088984812	[169]	[264]	4	hSpCas9	negative selection	11018022
24477041	24477064	18	+	28162770	P31FUJ	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.539103881638936	[823]	[1406]	6	hSpCas9	negative selection	11018023
24476867	24476890	18	+	28162770	P31FUJ	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.43516482306186366	[196]	[312]	5	hSpCas9	negative selection	11018024
24477025	24477048	18	-	28162770	P31FUJ	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.11046666149032625	[112]	[122]	-1	hSpCas9	negative selection	11018025
24476989	24477012	18	-	28162770	P31FUJ	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.3549616467809176	[685]	[1030]	4	hSpCas9	negative selection	11018026
24477011	24477034	18	+	28162770	P31FUJ	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.4995020123819646	[123]	[205]	5	hSpCas9	negative selection	11018027
24477051	24477074	18	-	28162770	P31FUJ	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.29624262418894665	[981]	[1416]	3	hSpCas9	negative selection	11018028
24477129	24477152	18	+	28162770	P31FUJ	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.5222457487352856	[332]	[561]	6	hSpCas9	negative selection	11018029
24460833	24460856	18	+	28162770	OCIAML5	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.5639197578083956	[94]	[506]	9	hSpCas9	negative selection	11187386
24477253	24477276	18	-	28162770	OCIAML5	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	-0.1550774524087295	[160]	[260]	-1	hSpCas9	negative selection	11187387
24460901	24460924	18	-	28162770	OCIAML5	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	-0.9058378273049776	[163]	[157]	-5	hSpCas9	negative selection	11187388
24477041	24477064	18	+	28162770	OCIAML5	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.5427930464772168	[377]	[993]	5	hSpCas9	negative selection	11187389
24476867	24476890	18	+	28162770	OCIAML5	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.3071320239852571	[149]	[334]	2	hSpCas9	negative selection	11187390
24477025	24477048	18	-	28162770	OCIAML5	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.6477080723578108	[45]	[52]	-4	hSpCas9	negative selection	11187391
24476989	24477012	18	-	28162770	OCIAML5	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.590591970700511	[290]	[790]	5	hSpCas9	negative selection	11187392
24477011	24477034	18	+	28162770	OCIAML5	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	-0.9100139200732764	[126]	[121]	-5	hSpCas9	negative selection	11187393
24477051	24477074	18	-	28162770	OCIAML5	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.16835890066812542	[525]	[1066]	1	hSpCas9	negative selection	11187394
24477129	24477152	18	+	28162770	OCIAML5	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.712718047919529	[119]	[354]	6	hSpCas9	negative selection	11187395
24460833	24460856	18	+	28162770	EOL1	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.1981514191145157	[339]	[410]	8	hSpCas9	negative selection	11356752
24477253	24477276	18	-	28162770	EOL1	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.5619776921858263	[296]	[230]	5	hSpCas9	negative selection	11356753
24460901	24460924	18	-	28162770	EOL1	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	1.4267178625753527	[256]	[363]	9	hSpCas9	negative selection	11356754
24477041	24477064	18	+	28162770	EOL1	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.22178003850525307	[1472]	[904]	2	hSpCas9	negative selection	11356755
24476867	24476890	18	+	28162770	EOL1	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.21488952340006362	[470]	[287]	2	hSpCas9	negative selection	11356756
24477025	24477048	18	-	28162770	EOL1	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.36495884562445036	[153]	[62]	-3	hSpCas9	negative selection	11356757
24476989	24477012	18	-	28162770	EOL1	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.5699994339284034	[602]	[213]	-4	hSpCas9	negative selection	11356758
24477011	24477034	18	+	28162770	EOL1	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.2543379842308673	[182]	[114]	2	hSpCas9	negative selection	11356759
24477051	24477074	18	-	28162770	EOL1	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.36037707245442996	[929]	[628]	3	hSpCas9	negative selection	11356760
24477129	24477152	18	+	28162770	EOL1	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.16017602006367657	[247]	[145]	1	hSpCas9	negative selection	11356761
24460833	24460856	18	+	28162770	MOLM13	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.169063856534193	[301]	[490]	8	hSpCas9	negative selection	11526118
24477253	24477276	18	-	28162770	MOLM13	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.6878971824358215	[345]	[402]	5	hSpCas9	negative selection	11526119
24460901	24460924	18	-	28162770	MOLM13	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.8521545320286061	[307]	[401]	6	hSpCas9	negative selection	11526120
24477041	24477064	18	+	28162770	MOLM13	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.8090586931615951	[1146]	[1452]	6	hSpCas9	negative selection	11526121
24476867	24476890	18	+	28162770	MOLM13	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.9064623952842117	[303]	[823]	9	hSpCas9	negative selection	11526122
24477025	24477048	18	-	28162770	MOLM13	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	0.3773770886391363	[147]	[138]	2	hSpCas9	negative selection	11526123
24476989	24477012	18	-	28162770	MOLM13	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	-0.5918404101350507	[862]	[413]	-3	hSpCas9	negative selection	11526124
24477011	24477034	18	+	28162770	MOLM13	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	1.2974210944468578	[165]	[294]	8	hSpCas9	negative selection	11526125
24477051	24477074	18	-	28162770	MOLM13	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.11384675388474852	[987]	[772]	0	hSpCas9	negative selection	11526126
24477129	24477152	18	+	28162770	MOLM13	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.5446151721874073	[237]	[250]	4	hSpCas9	negative selection	11526127
24460833	24460856	18	+	28162770	HEL	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	0.89245888455327	[253]	[301]	7	hSpCas9	negative selection	11695484
24477253	24477276	18	-	28162770	HEL	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.5366104811390139	[281]	[261]	4	hSpCas9	negative selection	11695485
24460901	24460924	18	-	28162770	HEL	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	-0.0386281526738617	[262]	[163]	0	hSpCas9	negative selection	11695486
24477041	24477064	18	+	28162770	HEL	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.8657771879976464	[956]	[1116]	7	hSpCas9	negative selection	11695487
24476867	24476890	18	+	28162770	HEL	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.9891289843296307	[268]	[341]	8	hSpCas9	negative selection	11695488
24477025	24477048	18	-	28162770	HEL	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	0.08787836306861974	[165]	[112]	0	hSpCas9	negative selection	11695489
24476989	24477012	18	-	28162770	HEL	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.29648531469340766	[627]	[493]	2	hSpCas9	negative selection	11695490
24477011	24477034	18	+	28162770	HEL	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	1.906846272499377	[111]	[268]	9	hSpCas9	negative selection	11695491
24477051	24477074	18	-	28162770	HEL	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	-0.09365641424741522	[842]	[505]	0	hSpCas9	negative selection	11695492
24477129	24477152	18	+	28162770	HEL	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	1.0939499438326858	[255]	[349]	8	hSpCas9	negative selection	11695493
24460833	24460856	18	+	28162770	MV411	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	0.6497077539877412	[226]	[299]	6	hSpCas9	negative selection	11864850
24477253	24477276	18	-	28162770	MV411	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.0658307442928276	[185]	[163]	0	hSpCas9	negative selection	11864851
24460901	24460924	18	-	28162770	MV411	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.3316505546858607	[182]	[193]	3	hSpCas9	negative selection	11864852
24477041	24477064	18	+	28162770	MV411	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.009365056658873883	[847]	[718]	0	hSpCas9	negative selection	11864853
24476867	24476890	18	+	28162770	MV411	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	1.0120594878518467	[185]	[315]	8	hSpCas9	negative selection	11864854
24477025	24477048	18	-	28162770	MV411	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	1.2201302047870402	[79]	[156]	9	hSpCas9	negative selection	11864855
24476989	24477012	18	-	28162770	MV411	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	1.1062181330509662	[310]	[563]	8	hSpCas9	negative selection	11864856
24477011	24477034	18	+	28162770	MV411	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.26026159114035874	[111]	[112]	2	hSpCas9	negative selection	11864857
24477051	24477074	18	-	28162770	MV411	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.24103030838963724	[676]	[673]	2	hSpCas9	negative selection	11864858
24477129	24477152	18	+	28162770	MV411	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.26137674174064907	[205]	[207]	2	hSpCas9	negative selection	11864859
24460833	24460856	18	+	28162770	MONOMAC1	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	-0.16883995522890177	[151]	[154]	-1	hSpCas9	negative selection	12034216
24477253	24477276	18	-	28162770	MONOMAC1	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	-0.4178055259163378	[147]	[126]	-4	hSpCas9	negative selection	12034217
24460901	24460924	18	-	28162770	MONOMAC1	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	1.2331075446094986	[94]	[255]	9	hSpCas9	negative selection	12034218
24477041	24477064	18	+	28162770	MONOMAC1	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.4111729346407449	[512]	[781]	4	hSpCas9	negative selection	12034219
24476867	24476890	18	+	28162770	MONOMAC1	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.8879711781469344	[172]	[366]	7	hSpCas9	negative selection	12034220
24477025	24477048	18	-	28162770	MONOMAC1	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	-0.7445246423620471	[56]	[38]	-6	hSpCas9	negative selection	12034221
24476989	24477012	18	-	28162770	MONOMAC1	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	1.1615810571569896	[263]	[676]	8	hSpCas9	negative selection	12034222
24477011	24477034	18	+	28162770	MONOMAC1	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.21283894710351126	[69]	[92]	2	hSpCas9	negative selection	12034223
24477051	24477074	18	-	28162770	MONOMAC1	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.13758196976399217	[497]	[627]	1	hSpCas9	negative selection	12034224
24477129	24477152	18	+	28162770	MONOMAC1	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.1311958246820176	[136]	[171]	1	hSpCas9	negative selection	12034225
24460833	24460856	18	+	28162770	OCIAML2	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	1.1515655816779704	[50]	[627]	9	hSpCas9	negative selection	12203582
24477253	24477276	18	-	28162770	OCIAML2	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	-0.7243864174879442	[61]	[207]	-5	hSpCas9	negative selection	12203583
24460901	24460924	18	-	28162770	OCIAML2	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.3895125111748783	[22]	[166]	4	hSpCas9	negative selection	12203584
24477041	24477064	18	+	28162770	OCIAML2	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.13535045674807789	[158]	[967]	1	hSpCas9	negative selection	12203585
24476867	24476890	18	+	28162770	OCIAML2	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.298364623116683	[48]	[333]	3	hSpCas9	negative selection	12203586
24477025	24477048	18	-	28162770	OCIAML2	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	0.13027421934801664	[14]	[90]	1	hSpCas9	negative selection	12203587
24476989	24477012	18	-	28162770	OCIAML2	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.19129465729387896	[72]	[461]	1	hSpCas9	negative selection	12203588
24477011	24477034	18	+	28162770	OCIAML2	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	1.5556494995566879	[16]	[276]	9	hSpCas9	negative selection	12203589
24477051	24477074	18	-	28162770	OCIAML2	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.3620754293601982	[136]	[975]	3	hSpCas9	negative selection	12203590
24477129	24477152	18	+	28162770	OCIAML2	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	0.31907723099601837	[46]	[324]	3	hSpCas9	negative selection	12203591
24460833	24460856	18	+	28162770	OCIAML3	viability	GGTCATTTTAGCTTTTGTGGTGG	HRH4	ENSG00000134489	2.048098767500602	[32]	[411]	9	hSpCas9	negative selection	12372948
24477253	24477276	18	-	28162770	OCIAML3	viability	GCAGTTCAACATGTTCCCTTTGG	HRH4	ENSG00000134489	0.4396231375571169	[52]	[216]	4	hSpCas9	negative selection	12372949
24460901	24460924	18	-	28162770	OCIAML3	viability	ACCCACAAAGAAGTCAGAGATGG	HRH4	ENSG00000134489	0.7499467608931982	[38]	[197]	6	hSpCas9	negative selection	12372950
24477041	24477064	18	+	28162770	OCIAML3	viability	GCTGTCTCTTCCAACATCTGTGG	HRH4	ENSG00000134489	0.4639979631114024	[194]	[811]	4	hSpCas9	negative selection	12372951
24476867	24476890	18	+	28162770	OCIAML3	viability	GAAGGTAGTGAATGTGAACCTGG	HRH4	ENSG00000134489	0.4315274517829744	[41]	[170]	4	hSpCas9	negative selection	12372952
24477025	24477048	18	-	28162770	OCIAML3	viability	AGACAGCAGTCAGTCCAGGATGG	HRH4	ENSG00000134489	0.1974057378644194	[12]	[44]	1	hSpCas9	negative selection	12372953
24476989	24477012	18	-	28162770	OCIAML3	viability	TGAGATGATCACGCTTCCACAGG	HRH4	ENSG00000134489	0.2727258288123724	[118]	[433]	2	hSpCas9	negative selection	12372954
24477011	24477034	18	+	28162770	OCIAML3	viability	AGTAGGTGCCAAAGCCATCCTGG	HRH4	ENSG00000134489	0.2578937206867029	[40]	[147]	2	hSpCas9	negative selection	12372955
24477051	24477074	18	-	28162770	OCIAML3	viability	GAATGAGTGTCCACAGATGTTGG	HRH4	ENSG00000134489	0.19875974551039466	[212]	[737]	2	hSpCas9	negative selection	12372956
24477129	24477152	18	+	28162770	OCIAML3	viability	CCTTTCATTCAGAGAGACAGAGG	HRH4	ENSG00000134489	-0.03010675513083666	[68]	[203]	0	hSpCas9	negative selection	12372957