Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3360
• Symbol:HTR4
• Description:5-hydroxytryptamine receptor 4

DataSource: http://genomecrispr.dkfz.de/#!/results/HTR4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
148509932	148509955	5	+	26472758	Jiyoye	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	0.5742853673411318	[170]	[191]	4	hSpCas9	negative selection	75260
148509703	148509726	5	+	26472758	Jiyoye	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.09871554822408402	[70]	[49]	0	hSpCas9	negative selection	75261
148550162	148550185	5	-	26472758	Jiyoye	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.777287009903201	[105]	[136]	5	hSpCas9	negative selection	75262
148509643	148509666	5	+	26472758	Jiyoye	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	-0.14351721713053664	[103]	[70]	-1	hSpCas9	negative selection	75263
148509545	148509568	5	+	26472758	Jiyoye	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	1.3998705808826402	[98]	[196]	8	hSpCas9	negative selection	75264
148509532	148509555	5	+	26472758	Jiyoye	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	1.3976526073873667	[75]	[150]	8	hSpCas9	negative selection	75265
148550252	148550275	5	-	26472758	Jiyoye	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	-0.29531042269777563	[440]	[270]	-2	hSpCas9	negative selection	75266
148550204	148550227	5	-	26472758	Jiyoye	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.4908333105527829	[133]	[141]	3	hSpCas9	negative selection	75267
148548750	148548773	5	-	26472758	Jiyoye	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.0286637582521434	[38]	[29]	0	hSpCas9	negative selection	75268
148509806	148509829	5	+	26472758	Jiyoye	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	-0.24490131507381974	[219]	[139]	-2	hSpCas9	negative selection	75269
148509932	148509955	5	+	26472758	KBM7	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	-0.11581394721787708	[1115,835]	[610,247]	-1	hSpCas9	negative selection	266378
148509703	148509726	5	+	26472758	KBM7	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	0.48755292408947437	[329,344]	[316,140]	5	hSpCas9	negative selection	266379
148550162	148550185	5	-	26472758	KBM7	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	-0.02418544733253769	[516,361]	[180,217]	0	hSpCas9	negative selection	266380
148509643	148509666	5	+	26472758	KBM7	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	1.3042037045777908	[525,251]	[548,337]	9	hSpCas9	negative selection	266381
148509545	148509568	5	+	26472758	KBM7	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	-0.5947876016087038	[429,409]	[72,182]	-5	hSpCas9	negative selection	266382
148509532	148509555	5	+	26472758	KBM7	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.247574830942023	[564,444]	[414,158]	2	hSpCas9	negative selection	266383
148550252	148550275	5	-	26472758	KBM7	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.4709371163160112	[1418,1559]	[930,1023]	5	hSpCas9	negative selection	266384
148550204	148550227	5	-	26472758	KBM7	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.3695202095337101	[760,891]	[327,669]	4	hSpCas9	negative selection	266385
148548750	148548773	5	-	26472758	KBM7	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.2999712252620468	[232,98]	[71,110]	3	hSpCas9	negative selection	266386
148509806	148509829	5	+	26472758	KBM7	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	1.2337536749601496	[528,466]	[665,445]	9	hSpCas9	negative selection	266387
148509932	148509955	5	+	26472758	Raji	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	0.6048831948444162	[288]	[101]	6	hSpCas9	negative selection	457496
148509703	148509726	5	+	26472758	Raji	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	0.3762002938013995	[82]	[24]	3	hSpCas9	negative selection	457497
148550162	148550185	5	-	26472758	Raji	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.7945960943427061	[235]	[94]	7	hSpCas9	negative selection	457498
148509643	148509666	5	+	26472758	Raji	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.7928729120487201	[193]	[77]	7	hSpCas9	negative selection	457499
148509545	148509568	5	+	26472758	Raji	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.16201879195044527	[284]	[73]	1	hSpCas9	negative selection	457500
148509532	148509555	5	+	26472758	Raji	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.6648652996726487	[211]	[77]	6	hSpCas9	negative selection	457501
148550252	148550275	5	-	26472758	Raji	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.289897933035298	[785]	[222]	2	hSpCas9	negative selection	457502
148550204	148550227	5	-	26472758	Raji	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.23417606602136976	[380]	[103]	2	hSpCas9	negative selection	457503
148548750	148548773	5	-	26472758	Raji	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-2.7703607145754026	[146]	[4]	-9	hSpCas9	negative selection	457504
148509806	148509829	5	+	26472758	Raji	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	-0.029155297574166072	[298]	[67]	0	hSpCas9	negative selection	457505
148509932	148509955	5	+	26472758	K562	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	1.1696618751688277	[702]	[1334]	8	hSpCas9	negative selection	648614
148509703	148509726	5	+	26472758	K562	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	1.0961387202641142	[214]	[387]	8	hSpCas9	negative selection	648615
148550162	148550185	5	-	26472758	K562	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.7636482629274266	[463]	[664]	6	hSpCas9	negative selection	648616
148509643	148509666	5	+	26472758	K562	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.4745118593544331	[346]	[406]	4	hSpCas9	negative selection	648617
148509545	148509568	5	+	26472758	K562	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.33927791400788787	[617]	[659]	2	hSpCas9	negative selection	648618
148509532	148509555	5	+	26472758	K562	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	-0.01425989944937922	[462]	[386]	0	hSpCas9	negative selection	648619
148550252	148550275	5	-	26472758	K562	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.498665116230256	[1234]	[1472]	4	hSpCas9	negative selection	648620
148550204	148550227	5	-	26472758	K562	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.25952562005665525	[569]	[575]	2	hSpCas9	negative selection	648621
148548750	148548773	5	-	26472758	K562	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.7761392071106239	[91]	[132]	6	hSpCas9	negative selection	648622
148509806	148509829	5	+	26472758	K562	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.805133682140926	[399]	[589]	6	hSpCas9	negative selection	648623
148509619	148509642	5	+	26627737	DLD1	viability	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.10017950831881894	[313]	[39,109,120]	-1	hSpCas9	negative selection	827441
148520939	148520962	5	-	26627737	DLD1	viability	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	-0.0013791637477686969	[93]	[18,36,31]	0	hSpCas9	negative selection	827442
148523277	148523300	5	+	26627737	DLD1	viability	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.7896674900171049	[453]	[259,361,135]	7	hSpCas9	negative selection	827443
148548775	148548798	5	+	26627737	DLD1	viability	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.07468635811524171	[845]	[355,261,224]	0	hSpCas9	negative selection	827444
148550228	148550251	5	-	26627737	DLD1	viability	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.3464508730907754	[543]	[142,130,127]	-4	hSpCas9	negative selection	827445
148665482	148665505	5	+	26627737	DLD1	viability	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.5924894707254003	[686]	[443,169,346]	6	hSpCas9	negative selection	827447
148509619	148509642	5	+	26627737	GBM cells	viability after 5 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.11588312704239484	[195]	[116,76]	-2	hSpCas9	negative selection	909756
148520939	148520962	5	-	26627737	GBM cells	viability after 5 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.382236113731004	[48]	[59,76]	9	hSpCas9	negative selection	909757
148523277	148523300	5	+	26627737	GBM cells	viability after 5 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.09428050624955941	[330]	[179,198]	1	hSpCas9	negative selection	909758
148548775	148548798	5	+	26627737	GBM cells	viability after 5 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	-0.20447927433474256	[534]	[293,203]	-3	hSpCas9	negative selection	909759
148550228	148550251	5	-	26627737	GBM cells	viability after 5 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.5183098726707158	[275]	[179,243]	7	hSpCas9	negative selection	909760
148665482	148665505	5	+	26627737	GBM cells	viability after 5 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	-0.02542185518224227	[389]	[178,231]	0	hSpCas9	negative selection	909762
148509619	148509642	5	+	26627737	GBM cells	viability after 13 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.09748899672327033	[195]	[158,76]	1	hSpCas9	negative selection	992071
148520939	148520962	5	-	26627737	GBM cells	viability after 13 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.3356973766585525	[48]	[65,67]	9	hSpCas9	negative selection	992072
148523277	148523300	5	+	26627737	GBM cells	viability after 13 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	-0.37721843855144105	[330]	[129,144]	-4	hSpCas9	negative selection	992073
148548775	148548798	5	+	26627737	GBM cells	viability after 13 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.20558490727196999	[534]	[433,253]	2	hSpCas9	negative selection	992074
148550228	148550251	5	-	26627737	GBM cells	viability after 13 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.3216639136616277	[275]	[222,157]	4	hSpCas9	negative selection	992075
148665482	148665505	5	+	26627737	GBM cells	viability after 13 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	-0.08009859545649411	[389]	[208,192]	-1	hSpCas9	negative selection	992077
148509619	148509642	5	+	26627737	GBM cells	viability after 21 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.8445163448409085	[195]	[63,54]	-6	hSpCas9	negative selection	1074386
148520939	148520962	5	-	26627737	GBM cells	viability after 21 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.2849288546730433	[48]	[67,61]	9	hSpCas9	negative selection	1074387
148523277	148523300	5	+	26627737	GBM cells	viability after 21 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.3840833185317435	[330]	[253,216]	4	hSpCas9	negative selection	1074388
148548775	148548798	5	+	26627737	GBM cells	viability after 21 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	-0.2789453203626576	[534]	[249,229]	-3	hSpCas9	negative selection	1074389
148550228	148550251	5	-	26627737	GBM cells	viability after 21 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.570306645864193	[275]	[230,214]	6	hSpCas9	negative selection	1074390
148665482	148665505	5	+	26627737	GBM cells	viability after 21 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	-0.10284986829775578	[389]	[201,192]	-1	hSpCas9	negative selection	1074392
148509619	148509642	5	+	26627737	RPE1	viability after 9 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.5185192298213699	[850]	[178,194]	-4	hSpCas9	negative selection	1156701
148520939	148520962	5	-	26627737	RPE1	viability after 9 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	4.455142768494334	[15]	[139,70]	9	hSpCas9	negative selection	1156702
148523277	148523300	5	+	26627737	RPE1	viability after 9 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	1.7408997499773005	[517]	[252,914]	8	hSpCas9	negative selection	1156703
148548775	148548798	5	+	26627737	RPE1	viability after 9 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	-0.01900337096573873	[1095]	[280,412]	0	hSpCas9	negative selection	1156704
148550228	148550251	5	-	26627737	RPE1	viability after 9 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.6356861743221353	[1128]	[377,769]	4	hSpCas9	negative selection	1156705
148665482	148665505	5	+	26627737	RPE1	viability after 9 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	-0.5233954338684386	[1174]	[251,260]	-4	hSpCas9	negative selection	1156707
148509619	148509642	5	+	26627737	RPE1	viability after 12 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-1.0004026422957042	[850]	[140,85]	-6	hSpCas9	negative selection	1239016
148520939	148520962	5	-	26627737	RPE1	viability after 12 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	4.9872067224234	[15]	[130,141]	9	hSpCas9	negative selection	1239017
148523277	148523300	5	+	26627737	RPE1	viability after 12 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	1.6218291104986613	[517]	[370,488]	8	hSpCas9	negative selection	1239018
148548775	148548798	5	+	26627737	RPE1	viability after 12 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.22314533383108343	[1095]	[180,515]	1	hSpCas9	negative selection	1239019
148550228	148550251	5	-	26627737	RPE1	viability after 12 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.6034574419981756	[1128]	[370,555]	4	hSpCas9	negative selection	1239020
148665482	148665505	5	+	26627737	RPE1	viability after 12 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	-0.2928648814660159	[1174]	[246,268]	-2	hSpCas9	negative selection	1239022
148509619	148509642	5	+	26627737	RPE1	viability after 15 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-1.3263039470929119	[850]	[95,95]	-7	hSpCas9	negative selection	1321331
148520939	148520962	5	-	26627737	RPE1	viability after 15 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	4.409462762755526	[15]	[113,78]	9	hSpCas9	negative selection	1321332
148523277	148523300	5	+	26627737	RPE1	viability after 15 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	1.8613760100732843	[517]	[395,663]	8	hSpCas9	negative selection	1321333
148548775	148548798	5	+	26627737	RPE1	viability after 15 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.391879822003621	[1095]	[361,449]	2	hSpCas9	negative selection	1321334
148550228	148550251	5	-	26627737	RPE1	viability after 15 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.5525944130970825	[1128]	[331,599]	3	hSpCas9	negative selection	1321335
148665482	148665505	5	+	26627737	RPE1	viability after 15 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.08903642931604938	[1174]	[519,192]	0	hSpCas9	negative selection	1321337
148509619	148509642	5	+	26627737	RPE1	viability after 18 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.963604135905104	[850]	[139,93]	-6	hSpCas9	negative selection	1403646
148520939	148520962	5	-	26627737	RPE1	viability after 18 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	4.6371294795701115	[15]	[134,77]	9	hSpCas9	negative selection	1403647
148523277	148523300	5	+	26627737	RPE1	viability after 18 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	2.0545480513579824	[517]	[382,791]	8	hSpCas9	negative selection	1403648
148548775	148548798	5	+	26627737	RPE1	viability after 18 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.28643016196270027	[1095]	[250,477]	1	hSpCas9	negative selection	1403649
148550228	148550251	5	-	26627737	RPE1	viability after 18 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	1.0071533309212026	[1128]	[550,677]	6	hSpCas9	negative selection	1403650
148665482	148665505	5	+	26627737	RPE1	viability after 18 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	-0.5825021155454151	[1174]	[262,156]	-4	hSpCas9	negative selection	1403652
148509619	148509642	5	+	26627737	HeLa	viability after 8 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.013719283269392424	[278]	[113,146,105]	0	hSpCas9	negative selection	1485961
148520939	148520962	5	-	26627737	HeLa	viability after 8 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.1348116614134502	[58]	[133,51,3]	8	hSpCas9	negative selection	1485962
148523277	148523300	5	+	26627737	HeLa	viability after 8 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.9711304543354149	[260]	[267,84,317]	7	hSpCas9	negative selection	1485963
148548775	148548798	5	+	26627737	HeLa	viability after 8 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.3597431874251791	[651]	[292,233,536]	3	hSpCas9	negative selection	1485964
148550228	148550251	5	-	26627737	HeLa	viability after 8 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.1147545618472936	[505]	[210,171,226]	-1	hSpCas9	negative selection	1485965
148665482	148665505	5	+	26627737	HeLa	viability after 8 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	1.2629231259387288	[453]	[514,467,449]	8	hSpCas9	negative selection	1485967
148509619	148509642	5	+	26627737	HeLa	viability after 12 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.6424868763395482	[278]	[98,57,66]	-5	hSpCas9	negative selection	1568276
148520939	148520962	5	-	26627737	HeLa	viability after 12 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.4353774897746203	[58]	[68,17,115]	8	hSpCas9	negative selection	1568277
148523277	148523300	5	+	26627737	HeLa	viability after 12 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.4898477801205488	[260]	[143,124,187]	4	hSpCas9	negative selection	1568278
148548775	148548798	5	+	26627737	HeLa	viability after 12 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.00858821925332387	[651]	[288,220,308]	0	hSpCas9	negative selection	1568279
148550228	148550251	5	-	26627737	HeLa	viability after 12 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.2295355084156282	[505]	[276,239,219]	2	hSpCas9	negative selection	1568280
148665482	148665505	5	+	26627737	HeLa	viability after 12 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.5417163557401927	[453]	[169,370,264]	4	hSpCas9	negative selection	1568282
148509619	148509642	5	+	26627737	HeLa	viability after 15 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.17182318203623942	[278]	[261,65,47]	1	hSpCas9	negative selection	1650591
148520939	148520962	5	-	26627737	HeLa	viability after 15 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.9018721383115795	[58]	[118,70,77]	9	hSpCas9	negative selection	1650592
148523277	148523300	5	+	26627737	HeLa	viability after 15 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.7629563826752822	[260]	[248,74,218]	6	hSpCas9	negative selection	1650593
148548775	148548798	5	+	26627737	HeLa	viability after 15 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	-0.23416397189105753	[651]	[324,193,150]	-2	hSpCas9	negative selection	1650594
148550228	148550251	5	-	26627737	HeLa	viability after 15 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.016988527603730652	[505]	[206,249,164]	0	hSpCas9	negative selection	1650595
148665482	148665505	5	+	26627737	HeLa	viability after 15 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.12409705045991554	[453]	[92,246,270]	1	hSpCas9	negative selection	1650597
148509619	148509642	5	+	26627737	HeLa	viability after 18 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.12160955101698129	[278]	[166,54,47]	1	hSpCas9	negative selection	1732906
148520939	148520962	5	-	26627737	HeLa	viability after 18 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.9484033362154398	[58]	[82,61,77]	9	hSpCas9	negative selection	1732907
148523277	148523300	5	+	26627737	HeLa	viability after 18 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.810089076810854	[260]	[173,67,218]	6	hSpCas9	negative selection	1732908
148548775	148548798	5	+	26627737	HeLa	viability after 18 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	-0.230795991642611	[651]	[221,156,150]	-2	hSpCas9	negative selection	1732909
148550228	148550251	5	-	26627737	HeLa	viability after 18 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.052503658125183095	[505]	[144,211,164]	0	hSpCas9	negative selection	1732910
148665482	148665505	5	+	26627737	HeLa	viability after 18 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.15535688681180743	[453]	[64,211,270]	1	hSpCas9	negative selection	1732912
148509619	148509642	5	+	26627737	HCT116	viability after 6 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	1.0494315255074531	[444]	[196,115]	6	hSpCas9	negative selection	1815221
148520939	148520962	5	-	26627737	HCT116	viability after 6 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	0.7964859314208725	[167]	[12,63]	4	hSpCas9	negative selection	1815222
148523277	148523300	5	+	26627737	HCT116	viability after 6 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	1.2693747810600606	[504]	[211,179]	6	hSpCas9	negative selection	1815223
148548775	148548798	5	+	26627737	HCT116	viability after 6 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	-0.3738611291930653	[1077]	[104,144]	-2	hSpCas9	negative selection	1815224
148550228	148550251	5	-	26627737	HCT116	viability after 6 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.10011918790115326	[488]	[14,102]	0	hSpCas9	negative selection	1815225
148665482	148665505	5	+	26627737	HCT116	viability after 6 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.8508863719928217	[791]	[172,252]	5	hSpCas9	negative selection	1815227
148509619	148509642	5	+	26627737	HCT116	viability after 8 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.43990717024735304	[155]	[59,62,66]	-5	hSpCas9	negative selection	1897536
148520939	148520962	5	-	26627737	HCT116	viability after 8 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	0.3951171495926791	[57]	[28,66,29]	4	hSpCas9	negative selection	1897537
148523277	148523300	5	+	26627737	HCT116	viability after 8 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.049938660003400415	[404]	[225,236,229]	0	hSpCas9	negative selection	1897538
148548775	148548798	5	+	26627737	HCT116	viability after 8 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.12917928171555007	[326]	[220,204,165]	1	hSpCas9	negative selection	1897539
148550228	148550251	5	-	26627737	HCT116	viability after 8 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.04438192282577458	[391]	[217,239,170]	0	hSpCas9	negative selection	1897540
148665482	148665505	5	+	26627737	HCT116	viability after 8 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.4231139346356628	[524]	[513,271,379]	4	hSpCas9	negative selection	1897542
148509619	148509642	5	+	26627737	HCT116	viability after 9 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.3642063419535262	[444]	[286,46]	2	hSpCas9	negative selection	1979851
148520939	148520962	5	-	26627737	HCT116	viability after 9 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	-2.6324873002580835	[167]	[4,8]	-9	hSpCas9	negative selection	1979852
148523277	148523300	5	+	26627737	HCT116	viability after 9 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.34672552312126004	[504]	[123,208]	2	hSpCas9	negative selection	1979853
148548775	148548798	5	+	26627737	HCT116	viability after 9 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	1.2845453629795003	[1077]	[455,894]	8	hSpCas9	negative selection	1979854
148550228	148550251	5	-	26627737	HCT116	viability after 9 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.45953737977754916	[488]	[283,96]	3	hSpCas9	negative selection	1979855
148665482	148665505	5	+	26627737	HCT116	viability after 9 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	-0.18339232038232206	[791]	[183,187]	-1	hSpCas9	negative selection	1979857
148509619	148509642	5	+	26627737	HCT116	viability after 12 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.7205856605633411	[155]	[35,71,42]	-7	hSpCas9	negative selection	2062166
148520939	148520962	5	-	26627737	HCT116	viability after 12 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.53941937280643	[57]	[41,92,134]	9	hSpCas9	negative selection	2062167
148523277	148523300	5	+	26627737	HCT116	viability after 12 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.06580766949264788	[404]	[225,138,300]	0	hSpCas9	negative selection	2062168
148548775	148548798	5	+	26627737	HCT116	viability after 12 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.3500923598378143	[326]	[214,198,242]	3	hSpCas9	negative selection	2062169
148550228	148550251	5	-	26627737	HCT116	viability after 12 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.07998196804425617	[391]	[149,291,218]	0	hSpCas9	negative selection	2062170
148665482	148665505	5	+	26627737	HCT116	viability after 12 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.2916822946752061	[524]	[368,237,400]	3	hSpCas9	negative selection	2062172
148509619	148509642	5	+	26627737	HCT116	viability after 15 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.09640877433132156	[155]	[57,149,74]	1	hSpCas9	negative selection	2144481
148520939	148520962	5	-	26627737	HCT116	viability after 15 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	0.4792829042138176	[57]	[45,25,66]	4	hSpCas9	negative selection	2144482
148523277	148523300	5	+	26627737	HCT116	viability after 15 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	-0.23664608926723163	[404]	[213,163,215]	-2	hSpCas9	negative selection	2144483
148548775	148548798	5	+	26627737	HCT116	viability after 15 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.6231837227194768	[326]	[299,273,294]	5	hSpCas9	negative selection	2144484
148550228	148550251	5	-	26627737	HCT116	viability after 15 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.053291915701044246	[391]	[328,158,176]	0	hSpCas9	negative selection	2144485
148665482	148665505	5	+	26627737	HCT116	viability after 15 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.3841491996719232	[524]	[549,212,435]	4	hSpCas9	negative selection	2144487
148509619	148509642	5	+	26627737	HCT116	viability after 18 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.5875996402434505	[155]	[79,186,65]	5	hSpCas9	negative selection	2226796
148520939	148520962	5	-	26627737	HCT116	viability after 18 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	0.6438945207366973	[57]	[5,45,80]	5	hSpCas9	negative selection	2226797
148523277	148523300	5	+	26627737	HCT116	viability after 18 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	-0.24340332550271399	[404]	[95,246,146]	-2	hSpCas9	negative selection	2226798
148548775	148548798	5	+	26627737	HCT116	viability after 18 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.5160506449398997	[326]	[242,220,213]	4	hSpCas9	negative selection	2226799
148550228	148550251	5	-	26627737	HCT116	viability after 18 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.3381101554817379	[391]	[341,211,162]	3	hSpCas9	negative selection	2226800
148665482	148665505	5	+	26627737	HCT116	viability after 18 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.175859394080081	[524]	[272,344,235]	1	hSpCas9	negative selection	2226802
148654629	148654652	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATAAACATGAAAGCGTTTGTGG	HTR4	ENSG00000164270	2.065162634376986	[155,223]	[28,332]	7	dCas9-VP64	positive selection	2384888
148654660	148654683	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATACAGGGATAGGATTTCCCTGG	HTR4	ENSG00000164270	1.2710579839131975	[176,77]	[112,16]	5	dCas9-VP64	positive selection	2384889
148654692	148654715	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGAGGCAGAGGCATAAGAAGG	HTR4	ENSG00000164270	2.5725338874280124	[168,99]	[247,96]	8	dCas9-VP64	positive selection	2384890
148637234	148637257	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATAAACCTTTTGTGACACTCGG	HTR4	ENSG00000164270	0.060174266839884805	[1051,390]	[150,177]	0	dCas9-VP64	positive selection	2392025
148637271	148637294	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCTTTGTGATTAAAACATATGG	HTR4	ENSG00000164270	-1.1256173444114677	[80,205]	[16,10]	-6	dCas9-VP64	positive selection	2392026
148637261	148637284	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAATCACAAAGCGATCAGTAGGG	HTR4	ENSG00000164270	-1.5134315618078387	[187,230]	[21,8]	-8	dCas9-VP64	positive selection	2392027
148610308	148610331	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGATCTCCAGCTGCGTACTGGG	HTR4	ENSG00000164270	1.3155837069749494	[204,54]	[116,20]	5	dCas9-VP64	positive selection	2419405
148609614	148609637	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGCGCGATCTAGG	HTR4	ENSG00000164270	-0.31087835177106626	[209,343]	[40,56]	-1	dCas9-VP64	positive selection	2443295
148647754	148647777	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAAGAATCGCTTGAACCCCGG	HTR4	ENSG00000164270	0.6947743245442068	[118,16]	[8,38]	3	dCas9-VP64	positive selection	2469068
148654629	148654652	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATAAACATGAAAGCGTTTGTGG	HTR4	ENSG00000164270	0.08604667061867599	[231,377]	[53,152]	0	dCas9-VP64	positive selection	2480143
148654660	148654683	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATACAGGGATAGGATTTCCCTGG	HTR4	ENSG00000164270	0.38359956604492773	[99,80]	[48,27]	3	dCas9-VP64	positive selection	2480144
148654692	148654715	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGAGGCAGAGGCATAAGAAGG	HTR4	ENSG00000164270	-0.43836523563530955	[190,195]	[50,41]	-4	dCas9-VP64	positive selection	2480145
148637234	148637257	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATAAACCTTTTGTGACACTCGG	HTR4	ENSG00000164270	2.485549385036075	[560,332]	[300,1310]	9	dCas9-VP64	positive selection	2487280
148637271	148637294	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCTTTGTGATTAAAACATATGG	HTR4	ENSG00000164270	0.05275691007118222	[56,15]	[14,8]	0	dCas9-VP64	positive selection	2487281
148637261	148637284	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAATCACAAAGCGATCAGTAGGG	HTR4	ENSG00000164270	-0.41223504659363996	[96,121]	[12,38]	-4	dCas9-VP64	positive selection	2487282
148610308	148610331	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGATCTCCAGCTGCGTACTGGG	HTR4	ENSG00000164270	-0.47381834665849165	[203,98]	[47,23]	-5	dCas9-VP64	positive selection	2514660
148609614	148609637	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGCGCGATCTAGG	HTR4	ENSG00000164270	0.057156110736217514	[593,444]	[221,134]	0	dCas9-VP64	positive selection	2538550
148647754	148647777	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAAGAATCGCTTGAACCCCGG	HTR4	ENSG00000164270	-1.217410828372933	[137,230]	[25,24]	-9	dCas9-VP64	positive selection	2564323
148548777	148548800	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCAGCTCAATGGCACCAAAGGG	HTR4	ENSG00000164270	-0.039195425225343083	[4,4]	[3,3]	0	hSpCas9	positive selection	2994515
148510013	148510036	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.6887991557414986	[2,2]	[3,4]	9	hSpCas9	positive selection	2994516
148550204	148550227	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.2200399442179044	[5,5]	[5,5]	4	hSpCas9	positive selection	2994517
148548705	148548728	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.22398732923222334	[3,3]	[4,0]	-3	hSpCas9	positive selection	2994518
148548777	148548800	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCAGCTCAATGGCACCAAAGGG	HTR4	ENSG00000164270	0.10423004883393128	[4,4]	[5,1]	1	hSpCas9	positive selection	3062373
148510013	148510036	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	-0.5306915098211531	[2,2]	[2,0]	-7	hSpCas9	positive selection	3062374
148550204	148550227	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.6879931380433346	[5,5]	[5,6]	9	hSpCas9	positive selection	3062375
148548705	148548728	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.17491741935908267	[3,3]	[4,1]	3	hSpCas9	positive selection	3062376
148548696	148548719		+	24336571	A375	resistance to PLX after 7 days	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.019604964270892644	[53,63]	[62,56]	0	hSpCas9	positive selection	3120100
148636988	148637011		-	24336571	A375	resistance to PLX after 7 days	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.07208337243510154	[64,71]	[66,62]	-2	hSpCas9	positive selection	3120101
148548705	148548728		-	24336571	A375	resistance to PLX after 7 days	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.0645071417414873	[70,60]	[65,70]	2	hSpCas9	positive selection	3120102
148548696	148548719		+	24336571	A375	resistance to PLX after 14 days	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.3199676506622078	[61,52]	[34,31]	3	hSpCas9	positive selection	3177893
148636988	148637011		-	24336571	A375	resistance to PLX after 14 days	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.38158239502907687	[65,71]	[22,25]	-4	hSpCas9	positive selection	3177894
148548705	148548728		-	24336571	A375	resistance to PLX after 14 days	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.9641086809659636	[70,58]	[61,56]	7	hSpCas9	positive selection	3177895
148548696	148548719		+	24336571	A375	viability after 7 days	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.10394814568363087	[57]	[53,63]	1	hSpCas9	negative selection	3235686
148636988	148637011		-	24336571	A375	viability after 7 days	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.30019597927632624	[58]	[64,71]	4	hSpCas9	negative selection	3235687
148548705	148548728		-	24336571	A375	viability after 7 days	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.3511566331267695	[53]	[70,60]	5	hSpCas9	negative selection	3235688
148548696	148548719		+	24336571	A375	viability after 14 days	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.07762154810241428	[57]	[61,52]	1	hSpCas9	negative selection	3293479
148636988	148637011		-	24336571	A375	viability after 14 days	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.32538801131538886	[58]	[65,71]	4	hSpCas9	negative selection	3293480
148548705	148548728		-	24336571	A375	viability after 14 days	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.3473784810301692	[53]	[70,58]	4	hSpCas9	negative selection	3293481
148548696	148548719	5	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.3049162127752376	[188,188]	[0,0]	-2	hSpCas9	positive selection	3373537
148636988	148637011	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.7925223380047265	[264,264]	[0,0]	-5	hSpCas9	positive selection	3373538
148548763	148548786	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	8.509283090324422	[206,206]	[492,492]	9	hSpCas9	positive selection	3373539
148548776	148548799	5	+	26780180	HT29	viability (Avana library 4 designs)	ACCAGCTCAATGGCACCAAAGGG	HTR4	ENSG00000164270	-0.614871733017805	[]	[]	-8	hSpCas9	negative selection	3431849
148510013	148510036	5	-	26780180	HT29	viability (Avana library 4 designs)	CCAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.745493794026144	[]	[]	3	hSpCas9	negative selection	3431850
148550204	148550227	5	-	26780180	HT29	viability (Avana library 4 designs)	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.105749352541776	[]	[]	0	hSpCas9	negative selection	3431851
148548705	148548728	5	-	26780180	HT29	viability (Avana library 4 designs)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.503167300579123	[]	[]	2	hSpCas9	negative selection	3431852
148510013	148510036	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	1.54938132381006	[]	[]	2	hSpCas9	negative selection	3517714
148548776	148548799	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCAGCTCAATGGCACCAAAGGG	HTR4	ENSG00000164270	-0.825713987120701	[]	[]	-1	hSpCas9	negative selection	3517715
148548705	148548728	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.403953406221309	[]	[]	0	hSpCas9	negative selection	3517716
148550204	148550227	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	-2.45464252882884	[]	[]	-3	hSpCas9	negative selection	3517717
148550251	148550274	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTCTTTCAGTTCTGAGGAGGG	HTR4	ENSG00000164270	3.5584404832027	[]	[]	5	hSpCas9	negative selection	3517718
148548750	148548773	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	3.87440005299542	[]	[]	6	hSpCas9	negative selection	3517719
148510013	148510036	5	-	26780180	A375	viability (Avana lentiGuide)	CCAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	3.6429743247025	[]	[]	3	hSpCas9	negative selection	3626373
148548776	148548799	5	+	26780180	A375	viability (Avana lentiGuide)	ACCAGCTCAATGGCACCAAAGGG	HTR4	ENSG00000164270	-4.40815356874321	[]	[]	-7	hSpCas9	negative selection	3626374
148548705	148548728	5	-	26780180	A375	viability (Avana lentiGuide)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	2.96613233425258	[]	[]	3	hSpCas9	negative selection	3626375
148550204	148550227	5	-	26780180	A375	viability (Avana lentiGuide)	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	-1.66677514555286	[]	[]	-3	hSpCas9	negative selection	3626376
148550251	148550274	5	-	26780180	A375	viability (Avana lentiGuide)	GTGTCTTTCAGTTCTGAGGAGGG	HTR4	ENSG00000164270	-3.58311150805081	[]	[]	-6	hSpCas9	negative selection	3626377
148548750	148548773	5	-	26780180	A375	viability (Avana lentiGuide)	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.177680252730042	[]	[]	0	hSpCas9	negative selection	3626378
148510013	148510036	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	-0.0484604546111847	[4]	[4,3]	-1	hSpCas9	positive selection	3735032
148548776	148548799	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCAGCTCAATGGCACCAAAGGG	HTR4	ENSG00000164270	-0.12093476378054938	[5]	[5,4]	-2	hSpCas9	positive selection	3735033
148548705	148548728	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.07705464878211052	[5]	[5,4]	-1	hSpCas9	positive selection	3735034
148550204	148550227	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.05734561667570323	[6]	[6,5]	1	hSpCas9	positive selection	3735035
148550251	148550274	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTCTTTCAGTTCTGAGGAGGG	HTR4	ENSG00000164270	0.18725016881704434	[5]	[6,6]	5	hSpCas9	positive selection	3735036
148548750	148548773	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.16159838799390902	[5]	[5,5]	4	hSpCas9	positive selection	3735037
148510013	148510036	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.14484653317220614	[4]	[3,4]	3	hSpCas9	positive selection	3843639
148548776	148548799	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCAGCTCAATGGCACCAAAGGG	HTR4	ENSG00000164270	0.1939079405805295	[6]	[6,5]	5	hSpCas9	positive selection	3843640
148548705	148548728	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.12504879995923118	[5]	[4,4]	-2	hSpCas9	positive selection	3843641
148550204	148550227	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.3038202262905273	[7]	[7,7]	8	hSpCas9	positive selection	3843642
148550251	148550274	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTCTTTCAGTTCTGAGGAGGG	HTR4	ENSG00000164270	0.4013875741369741	[5]	[6,6]	9	hSpCas9	positive selection	3843643
148548750	148548773	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.12539435052689485	[6]	[6,5]	3	hSpCas9	positive selection	3843644
148548696	148548719	5	+	26780180	A375	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.934215448398242	[]	[]	4	hSpCas9	negative selection	3949612
148636988	148637011	5	-	26780180	A375	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.671836506957702	[]	[]	2	hSpCas9	negative selection	3949613
148523275	148523298	5	+	26780180	A375	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	1.03610764160001	[]	[]	5	hSpCas9	negative selection	3949614
148523273	148523296	5	-	26780180	A375	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	1.62087334187668	[]	[]	8	hSpCas9	negative selection	3949615
148548705	148548728	5	-	26780180	A375	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	1.13924838570931	[]	[]	6	hSpCas9	negative selection	3949616
148548763	148548786	5	-	26780180	A375	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.853355146200333	[]	[]	3	hSpCas9	negative selection	3949617
148548696	148548719	5	+	26780180	HT29	viability (GeCKOv2 library)	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.923025973441861	[]	[]	4	hSpCas9	negative selection	4057578
148636988	148637011	5	-	26780180	HT29	viability (GeCKOv2 library)	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	1.12573272146223	[]	[]	5	hSpCas9	negative selection	4057579
148523275	148523298	5	+	26780180	HT29	viability (GeCKOv2 library)	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.653733271287652	[]	[]	2	hSpCas9	negative selection	4057580
148523273	148523296	5	-	26780180	HT29	viability (GeCKOv2 library)	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	1.99528236181946	[]	[]	9	hSpCas9	negative selection	4057581
148548705	148548728	5	-	26780180	HT29	viability (GeCKOv2 library)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.644688844301754	[]	[]	2	hSpCas9	negative selection	4057582
148548763	148548786	5	-	26780180	HT29	viability (GeCKOv2 library)	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.840004511698746	[]	[]	3	hSpCas9	negative selection	4057583
148548696	148548719	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.2408682213055391	[5]	[3,5]	6	hSpCas9	positive selection	4143685
148636988	148637011	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.38362161466142475	[6]	[6,4]	8	hSpCas9	positive selection	4143686
148548705	148548728	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.3103293841253364	[5]	[3,5]	7	hSpCas9	positive selection	4143687
148548696	148548719	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.15897824321862764	[5]	[3,2,5,0]	1	hSpCas9	positive selection	4207707
148636988	148637011	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.9923010009087581	[6]	[5,5,6,4]	7	hSpCas9	positive selection	4207708
148548705	148548728	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	1.03359881705867	[5]	[5,3,5,4]	7	hSpCas9	positive selection	4207709
148523273	148523296	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.03704707397848633	[3]	[3,2]	0	hSpCas9	positive selection	4276074
148523275	148523298	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.1249751138275399	[2]	[1,1]	-2	hSpCas9	positive selection	4276075
148548705	148548728	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.03856377746734707	[3]	[3,1]	0	hSpCas9	positive selection	4276076
148548696	148548719	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.07054505671007777	[2]	[2,1]	-1	hSpCas9	positive selection	4340332
148636988	148637011	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.6123604832787608	[3]	[3,4]	9	hSpCas9	positive selection	4340333
148548763	148548786	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.10647205631223469	[3]	[3,1]	2	hSpCas9	positive selection	4340334
148510013	148510035	5	-	27760321	OCIAML3	viability	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.31504169865538056	[92,58]	[74,69]	3	hSpCas9	negative selection	4408427
148523206	148523228	5	-	27760321	OCIAML3	viability	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	-0.31983253168276127	[104,96]	[51,77]	-3	hSpCas9	negative selection	4408428
148523273	148523295	5	-	27760321	OCIAML3	viability	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.8520395455310792	[319,288]	[402,463]	8	hSpCas9	negative selection	4408429
148523307	148523329	5	+	27760321	OCIAML3	viability	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.812096830079656	[336,307]	[107,189]	-6	hSpCas9	negative selection	4408430
148548697	148548719	5	+	27760321	OCIAML3	viability	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.12712997226647904	[948,879]	[552,787]	-1	hSpCas9	negative selection	4408431
148510013	148510035	5	-	27760321	OCIAML2	viability	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	-0.234177598732475	[92,58]	[22,88]	-3	hSpCas9	negative selection	4491890
148523206	148523228	5	-	27760321	OCIAML2	viability	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	0.32195625682879836	[104,96]	[102,100]	4	hSpCas9	negative selection	4491891
148523273	148523295	5	-	27760321	OCIAML2	viability	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.1103506904598695	[319,288]	[250,284]	1	hSpCas9	negative selection	4491892
148523307	148523329	5	+	27760321	OCIAML2	viability	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.5767689477541786	[336,307]	[217,117]	-6	hSpCas9	negative selection	4491893
148548697	148548719	5	+	27760321	OCIAML2	viability	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.04083250403585903	[948,879]	[635,828]	0	hSpCas9	negative selection	4491894
148510013	148510035	5	-	27760321	MV411	viability	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	1.2347404469284757	[92,58]	[174,27]	8	hSpCas9	negative selection	4575353
148523206	148523228	5	-	27760321	MV411	viability	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	-2.114530239316837	[104,96]	[4,30]	-8	hSpCas9	negative selection	4575354
148523273	148523295	5	-	27760321	MV411	viability	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.02314342112923462	[319,288]	[211,191]	0	hSpCas9	negative selection	4575355
148523307	148523329	5	+	27760321	MV411	viability	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-1.1547722861446228	[336,307]	[29,193]	-6	hSpCas9	negative selection	4575356
148548697	148548719	5	+	27760321	MV411	viability	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.7564908791789795	[948,879]	[892,1209]	5	hSpCas9	negative selection	4575357
148510013	148510035	5	-	27760321	HL60	viability	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.5528820008075028	[92,58]	[112,64]	6	hSpCas9	negative selection	4658816
148523206	148523228	5	-	27760321	HL60	viability	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	-1.682589893694705	[104,96]	[48,0]	-9	hSpCas9	negative selection	4658817
148523273	148523295	5	-	27760321	HL60	viability	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.42612571540188277	[319,288]	[330,336]	5	hSpCas9	negative selection	4658818
148523307	148523329	5	+	27760321	HL60	viability	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.24980157774842277	[336,307]	[120,327]	-3	hSpCas9	negative selection	4658819
148548697	148548719	5	+	27760321	HL60	viability	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.031292730881078645	[948,879]	[652,813]	0	hSpCas9	negative selection	4658820
148510013	148510035	5	-	27760321	HT1080	viability	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.4129168129819041	[58,45]	[13,42]	2	hSpCas9	negative selection	4742279
148523206	148523228	5	-	27760321	HT1080	viability	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	-5.107158541575956	[96,75]	[0,0]	-8	hSpCas9	negative selection	4742280
148523273	148523295	5	-	27760321	HT1080	viability	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.0025590042001464863	[288,225]	[89,115]	0	hSpCas9	negative selection	4742281
148523307	148523329	5	+	27760321	HT1080	viability	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-1.186018807017701	[307,240]	[38,57]	-5	hSpCas9	negative selection	4742282
148548697	148548719	5	+	27760321	HT1080	viability	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.39155984709868075	[879,686]	[67,423]	-2	hSpCas9	negative selection	4742283
148510013	148510035	5	-	27760321	HT29	viability after 7 days	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.5720688899179205	[58,45]	[77,128,90]	8	hSpCas9	negative selection	4825742
148523206	148523228	5	-	27760321	HT29	viability after 7 days	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	0.022185962921936753	[96,75]	[186,71,90]	0	hSpCas9	negative selection	4825743
148523273	148523295	5	-	27760321	HT29	viability after 7 days	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.09839853246004349	[288,225]	[438,281,353]	1	hSpCas9	negative selection	4825744
148523307	148523329	5	+	27760321	HT29	viability after 7 days	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.36371558329509474	[307,240]	[422,89,328]	-5	hSpCas9	negative selection	4825745
148548697	148548719	5	+	27760321	HT29	viability after 7 days	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.3604040417747211	[879,686]	[796,782,774]	-5	hSpCas9	negative selection	4825746
148510013	148510035	5	-	27760321	HT29	viability after 25 days	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.5773396632161081	[58,45]	[77,76,116]	6	hSpCas9	negative selection	4909205
148523206	148523228	5	-	27760321	HT29	viability after 25 days	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	0.035256128843175194	[96,75]	[71,94,142]	0	hSpCas9	negative selection	4909206
148523273	148523295	5	-	27760321	HT29	viability after 25 days	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.1545057451828708	[288,225]	[222,298,482]	1	hSpCas9	negative selection	4909207
148523307	148523329	5	+	27760321	HT29	viability after 25 days	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.9845625681026213	[307,240]	[196,134,138]	-6	hSpCas9	negative selection	4909208
148548697	148548719	5	+	27760321	HT29	viability after 25 days	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.052813210411370104	[879,686]	[911,626,1283]	0	hSpCas9	negative selection	4909209
148510013	148510035	5	-	27760321	HT29	viability after 22 days	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.9784576082606622	[58,45]	[90,96,171]	9	hSpCas9	negative selection	4992668
148523206	148523228	5	-	27760321	HT29	viability after 22 days	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	0.660256439546141	[96,75]	[119,221,132]	7	hSpCas9	negative selection	4992669
148523273	148523295	5	-	27760321	HT29	viability after 22 days	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.08190158572931289	[288,225]	[196,384,366]	0	hSpCas9	negative selection	4992670
148523307	148523329	5	+	27760321	HT29	viability after 22 days	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-1.107718277907637	[307,240]	[192,56,190]	-7	hSpCas9	negative selection	4992671
148548697	148548719	5	+	27760321	HT29	viability after 22 days	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.4322885750807912	[879,686]	[582,671,761]	-4	hSpCas9	negative selection	4992672
148510013	148510035	5	-	27760321	HT29	viability after 19 days	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	1.8420563899692968	[58,45]	[123,187,319]	9	hSpCas9	negative selection	5076131
148523206	148523228	5	-	27760321	HT29	viability after 19 days	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	-0.2942358276355117	[96,75]	[19,89,123]	-3	hSpCas9	negative selection	5076132
148523273	148523295	5	-	27760321	HT29	viability after 19 days	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.46109022791708226	[288,225]	[392,502,321]	4	hSpCas9	negative selection	5076133
148523307	148523329	5	+	27760321	HT29	viability after 19 days	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.04676611363574018	[307,240]	[471,171,285]	0	hSpCas9	negative selection	5076134
148548697	148548719	5	+	27760321	HT29	viability after 19 days	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.06560203759794714	[879,686]	[1011,938,871]	0	hSpCas9	negative selection	5076135
148510013	148510035	5	-	27760321	HT29	viability after 16 days	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	1.2711783612472842	[58,45]	[119,110,192]	9	hSpCas9	negative selection	5159594
148523206	148523228	5	-	27760321	HT29	viability after 16 days	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	0.4278526333667343	[96,75]	[80,52,253]	5	hSpCas9	negative selection	5159595
148523273	148523295	5	-	27760321	HT29	viability after 16 days	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.05517055883202171	[288,225]	[243,382,198]	0	hSpCas9	negative selection	5159596
148523307	148523329	5	+	27760321	HT29	viability after 16 days	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.7931795414261387	[307,240]	[238,83,216]	-6	hSpCas9	negative selection	5159597
148548697	148548719	5	+	27760321	HT29	viability after 16 days	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.15287373981044905	[879,686]	[857,781,731]	-2	hSpCas9	negative selection	5159598
148510013	148510035	5	-	27760321	HT29	viability after 13 days	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	1.1180281817384872	[58,45]	[44,240,111]	9	hSpCas9	negative selection	5243057
148523206	148523228	5	-	27760321	HT29	viability after 13 days	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	0.6507513438419688	[96,75]	[112,136,218]	8	hSpCas9	negative selection	5243058
148523273	148523295	5	-	27760321	HT29	viability after 13 days	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.0971625039402696	[288,225]	[175,380,280]	-1	hSpCas9	negative selection	5243059
148523307	148523329	5	+	27760321	HT29	viability after 13 days	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-0.7849881563337004	[307,240]	[283,97,172]	-7	hSpCas9	negative selection	5243060
148548697	148548719	5	+	27760321	HT29	viability after 13 days	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.11390078087104749	[879,686]	[1001,756,764]	-1	hSpCas9	negative selection	5243061
148510013	148510035	5	-	27760321	HT29	viability after 10 days	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	0.541511682745945	[58,45]	[31,99,152]	7	hSpCas9	negative selection	5326520
148523206	148523228	5	-	27760321	HT29	viability after 10 days	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	1.066198148723473	[96,75]	[80,239,354]	9	hSpCas9	negative selection	5326521
148523273	148523295	5	-	27760321	HT29	viability after 10 days	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.5045138715968452	[288,225]	[87,209,377]	-6	hSpCas9	negative selection	5326522
148523307	148523329	5	+	27760321	HT29	viability after 10 days	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	-1.2845861766978797	[307,240]	[110,171,139]	-8	hSpCas9	negative selection	5326523
148548697	148548719	5	+	27760321	HT29	viability after 10 days	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-1.0262608435046308	[879,686]	[590,453,396]	-8	hSpCas9	negative selection	5326524
148510013	148510035	5	-	27760321	MOLM13	viability	CAACTCTCAGATAGAAAAGAGG	HTR4	ENSG00000164270	1.3303493782314368	[92,58]	[42,159]	8	hSpCas9	negative selection	5409983
148523206	148523228	5	-	27760321	MOLM13	viability	TGCAAGGCTGGAATAACATTGG	HTR4	ENSG00000164270	-0.17862116708066056	[104,96]	[85,19]	-1	hSpCas9	negative selection	5409984
148523273	148523295	5	-	27760321	MOLM13	viability	CTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.4672778999491649	[319,288]	[74,165]	-3	hSpCas9	negative selection	5409985
148523307	148523329	5	+	27760321	MOLM13	viability	GTTCCTATAGACCAAAGGCTGG	HTR4	ENSG00000164270	0.06591659652891152	[336,307]	[117,251]	0	hSpCas9	negative selection	5409986
148548697	148548719	5	+	27760321	MOLM13	viability	AATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.41270867892473884	[948,879]	[371,400]	-3	hSpCas9	negative selection	5409987
148654086	148654109	5	+	27661255	K562	viability	GGTGCCCTGGCAGATTCGAGCGG	HTR4	ENSG00000164270	0.14156517586709383	[1427,1621]	[1432,1261]	5	dCas9-KRAB	negative selection	5485866
148654426	148654449	5	+	27661255	K562	viability	GGCAGGGCGCACAGGGGAGTGGG	HTR4	ENSG00000164270	0.15213880617622222	[325,506]	[409,329]	5	dCas9-KRAB	negative selection	5485867
148654090	148654113	5	-	27661255	K562	viability	GTGGCCGCTCGAATCTGCCAGGG	HTR4	ENSG00000164270	0.035545618757403696	[2373,2498]	[2175,1836]	1	dCas9-KRAB	negative selection	5485868
148654119	148654142	5	-	27661255	K562	viability	GCAGCAGAAGCTCGGCTCAGCGG	HTR4	ENSG00000164270	0.10185230944820656	[617,552]	[591,426]	3	dCas9-KRAB	negative selection	5485869
148523273	148523296	5	-	27260156	BXPC3	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.06088068702588556	[852]	[757,780,933,971]	-1	hSpCas9	negative selection	5548534
148523275	148523298	5	+	27260156	BXPC3	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.38553187553462087	[202]	[173,150,136,188]	-7	hSpCas9	negative selection	5548535
148548705	148548728	5	-	27260156	BXPC3	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.003143078444545755	[845]	[805,862,903,989]	0	hSpCas9	negative selection	5548536
148548696	148548719	5	+	27260156	BXPC3	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.4475373214090773	[424]	[325,251,302,437]	-7	hSpCas9	negative selection	5612792
148636988	148637011	5	-	27260156	BXPC3	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.135432688501395	[575]	[555,410,650,584]	-3	hSpCas9	negative selection	5612793
148548763	148548786	5	-	27260156	BXPC3	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.33551906646376944	[509]	[658,843,504,665]	7	hSpCas9	negative selection	5612794
148523273	148523296	5	-	27260156	A673	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.04985768879661834	[852]	[961,934,1041,1015]	-1	hSpCas9	negative selection	5669785
148523275	148523298	5	+	27260156	A673	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.20293576008440728	[202]	[266,164,213,207]	-5	hSpCas9	negative selection	5669786
148548705	148548728	5	-	27260156	A673	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.07840420720079877	[845]	[1221,936,1088,1059]	1	hSpCas9	negative selection	5669787
148548696	148548719	5	+	27260156	A673	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.09417568064740578	[424]	[619,418,409,480]	-2	hSpCas9	negative selection	5734043
148636988	148637011	5	-	27260156	A673	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.014025131917423828	[575]	[740,531,714,764]	0	hSpCas9	negative selection	5734044
148548763	148548786	5	-	27260156	A673	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	-0.05261530872352696	[509]	[604,628,547,578]	-1	hSpCas9	negative selection	5734045
148523273	148523296	5	-	27260156	A375	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.16265024683964435	[852]	[949,1023,749,855]	-2	hSpCas9	negative selection	5791036
148523275	148523298	5	+	27260156	A375	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-1.2852153482011948	[202]	[33,176,142,50]	-9	hSpCas9	negative selection	5791037
148548705	148548728	5	-	27260156	A375	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.14922104779938117	[845]	[783,1262,1037,565]	-2	hSpCas9	negative selection	5791038
148548696	148548719	5	+	27260156	A375	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.0634034147497631	[424]	[446,632,478,527]	0	hSpCas9	negative selection	5855294
148636988	148637011	5	-	27260156	A375	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.008872536259802166	[575]	[811,600,668,590]	0	hSpCas9	negative selection	5855295
148548763	148548786	5	-	27260156	A375	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.1750553670964642	[509]	[580,720,630,750]	2	hSpCas9	negative selection	5855296
148523273	148523296	5	-	27260156	COLO741	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.2798923408153213	[852]	[1030,869,807]	-5	hSpCas9	negative selection	5912287
148523275	148523298	5	+	27260156	COLO741	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.5110043241351467	[202]	[194,145,203]	-8	hSpCas9	negative selection	5912288
148548705	148548728	5	-	27260156	COLO741	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.02286067101391931	[845]	[945,1338,1001]	0	hSpCas9	negative selection	5912289
148548696	148548719	5	+	27260156	COLO741	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.11862541224105502	[424]	[597,402,505]	-3	hSpCas9	negative selection	5976545
148636988	148637011	5	-	27260156	COLO741	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.04683208798054961	[575]	[626,838,798]	1	hSpCas9	negative selection	5976546
148548763	148548786	5	-	27260156	COLO741	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.21660858620154566	[509]	[879,711,692]	4	hSpCas9	negative selection	5976547
148523273	148523296	5	-	27260156	CAL120	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.002899868339262479	[852]	[1616,894,754]	0	hSpCas9	negative selection	6033538
148523275	148523298	5	+	27260156	CAL120	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.873458112373364	[202]	[160,169,86]	-8	hSpCas9	negative selection	6033539
148548705	148548728	5	-	27260156	CAL120	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.1839481835418041	[845]	[1094,776,932]	-3	hSpCas9	negative selection	6033540
148548696	148548719	5	+	27260156	CAL120	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.1066619350553504	[424]	[590,498,399]	-1	hSpCas9	negative selection	6097796
148636988	148637011	5	-	27260156	CAL120	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.33256924153682904	[575]	[562,949,1138]	5	hSpCas9	negative selection	6097797
148548763	148548786	5	-	27260156	CAL120	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.17532405637970938	[509]	[696,750,698]	2	hSpCas9	negative selection	6097798
148523273	148523296	5	-	27260156	CADOES1	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.18476086569593486	[852]	[912,922,867,902]	3	hSpCas9	negative selection	6154789
148523275	148523298	5	+	27260156	CADOES1	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.5433114371753229	[202]	[117,171,132,93]	-7	hSpCas9	negative selection	6154790
148548705	148548728	5	-	27260156	CADOES1	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.1298539339317214	[845]	[736,636,863,634]	-2	hSpCas9	negative selection	6154791
148548696	148548719	5	+	27260156	CADOES1	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.3656330968944139	[424]	[356,294,267,306]	-6	hSpCas9	negative selection	6219047
148636988	148637011	5	-	27260156	CADOES1	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.03119612253208559	[575]	[588,615,532,447]	0	hSpCas9	negative selection	6219048
148548763	148548786	5	-	27260156	CADOES1	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.26415183695893835	[509]	[707,564,491,510]	4	hSpCas9	negative selection	6219049
148523273	148523296	5	-	27260156	EWS502	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.12179331666455984	[852]	[705,766,884,989]	-2	hSpCas9	negative selection	6276040
148523275	148523298	5	+	27260156	EWS502	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.5204873802206369	[202]	[79,206,174,142]	-7	hSpCas9	negative selection	6276041
148548705	148548728	5	-	27260156	EWS502	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.2692476565800075	[845]	[576,663,842,924]	-5	hSpCas9	negative selection	6276042
148548696	148548719	5	+	27260156	EWS502	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.06812505866259631	[424]	[353,494,574,476]	1	hSpCas9	negative selection	6340298
148636988	148637011	5	-	27260156	EWS502	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.0091586902248319	[575]	[612,679,541,614]	0	hSpCas9	negative selection	6340299
148548763	148548786	5	-	27260156	EWS502	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.35017797446134735	[509]	[605,606,856,697]	6	hSpCas9	negative selection	6340300
148523273	148523296	5	-	27260156	EW8	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.2019862939000332	[852]	[594,672,546,595]	-4	hSpCas9	negative selection	6397291
148523275	148523298	5	+	27260156	EW8	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.4813290818646234	[202]	[121,163,26,173]	-7	hSpCas9	negative selection	6397292
148548705	148548728	5	-	27260156	EW8	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.010808541069313393	[845]	[667,810,611,639]	0	hSpCas9	negative selection	6397293
148548696	148548719	5	+	27260156	EW8	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.28676339856246114	[424]	[280,397,247,207]	-5	hSpCas9	negative selection	6461549
148636988	148637011	5	-	27260156	EW8	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.05397917150750031	[575]	[556,582,291,545]	1	hSpCas9	negative selection	6461550
148548763	148548786	5	-	27260156	EW8	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.42960222494960504	[509]	[678,449,478,642]	7	hSpCas9	negative selection	6461551
148523273	148523296	5	-	27260156	CORL105	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.029369419134391506	[852]	[1097,1075,985,912]	0	hSpCas9	negative selection	6518542
148523275	148523298	5	+	27260156	CORL105	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.7061003645522141	[202]	[158,150,138,132]	-8	hSpCas9	negative selection	6518543
148548705	148548728	5	-	27260156	CORL105	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.06454775206127972	[845]	[1123,880,1283,898]	1	hSpCas9	negative selection	6518544
148548696	148548719	5	+	27260156	CORL105	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.057108456543914	[424]	[386,591,543,394]	-1	hSpCas9	negative selection	6582800
148636988	148637011	5	-	27260156	CORL105	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.09104343456971675	[575]	[736,620,924,624]	1	hSpCas9	negative selection	6582801
148548763	148548786	5	-	27260156	CORL105	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.06565908512783926	[509]	[665,617,656,564]	1	hSpCas9	negative selection	6582802
148523273	148523296	5	-	27260156	HS294T	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.4604623938684119	[852]	[367,544,361,561]	6	hSpCas9	negative selection	6639793
148523275	148523298	5	+	27260156	HS294T	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.1062002136437632	[202]	[91,79,60,107]	1	hSpCas9	negative selection	6639794
148548705	148548728	5	-	27260156	HS294T	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.1803112140428943	[845]	[240,368,224,326]	-3	hSpCas9	negative selection	6639795
148548696	148548719	5	+	27260156	HS294T	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.07014887595669772	[424]	[140,93,238,154]	-1	hSpCas9	negative selection	6704051
148636988	148637011	5	-	27260156	HS294T	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.2070828975791265	[575]	[242,135,161,233]	-3	hSpCas9	negative selection	6704052
148548763	148548786	5	-	27260156	HS294T	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	1.1946844723197048	[509]	[679,312,203,616]	9	hSpCas9	negative selection	6704053
148523273	148523296	5	-	27260156	HCC44	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.10102197288092551	[852]	[1236,688,1367,963]	1	hSpCas9	negative selection	6761044
148523275	148523298	5	+	27260156	HCC44	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.45272868747015216	[202]	[207,308,398,342]	7	hSpCas9	negative selection	6761045
148548705	148548728	5	-	27260156	HCC44	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.052445656281942865	[845]	[819,999,1210,951]	0	hSpCas9	negative selection	6761046
148548696	148548719	5	+	27260156	HCC44	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.2615161771704451	[424]	[753,287,730,609]	4	hSpCas9	negative selection	6825302
148636988	148637011	5	-	27260156	HCC44	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.10069536688739678	[575]	[650,614,955,620]	1	hSpCas9	negative selection	6825303
148548763	148548786	5	-	27260156	HCC44	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.24907923951845384	[509]	[653,638,897,588]	4	hSpCas9	negative selection	6825304
148523273	148523296	5	-	27260156	G402	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.01823154684960593	[852]	[1388,989,869,1009]	0	hSpCas9	negative selection	6882295
148523275	148523298	5	+	27260156	G402	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.25582682977377036	[202]	[277,435,315,163]	3	hSpCas9	negative selection	6882296
148548705	148548728	5	-	27260156	G402	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.27929014656841245	[845]	[1375,1203,1331,1115]	3	hSpCas9	negative selection	6882297
148548696	148548719	5	+	27260156	G402	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.35602772441550523	[424]	[613,272,166,578]	-4	hSpCas9	negative selection	6946553
148636988	148637011	5	-	27260156	G402	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.06397060134645496	[575]	[740,753,799,418]	-1	hSpCas9	negative selection	6946554
148548763	148548786	5	-	27260156	G402	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.22273262780565672	[509]	[766,381,655,1065]	3	hSpCas9	negative selection	6946555
148523273	148523296	5	-	27260156	L33	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.20273352331435046	[852]	[1154,342,593,984]	4	hSpCas9	negative selection	7003546
148523275	148523298	5	+	27260156	L33	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.6124216865638998	[202]	[151,39,101,118]	-8	hSpCas9	negative selection	7003547
148548705	148548728	5	-	27260156	L33	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.13279987098933965	[845]	[735,332,468,791]	-3	hSpCas9	negative selection	7003548
148548696	148548719	5	+	27260156	L33	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.009870707544948454	[424]	[416,133,331,439]	0	hSpCas9	negative selection	7067804
148636988	148637011	5	-	27260156	L33	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.1755127481318216	[575]	[483,197,389,453]	-4	hSpCas9	negative selection	7067805
148548763	148548786	5	-	27260156	L33	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.17542879263068023	[509]	[460,232,387,658]	4	hSpCas9	negative selection	7067806
148523273	148523296	5	-	27260156	K562	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.06418764309803449	[852]	[809,932,794,649]	0	hSpCas9	negative selection	7124797
148523275	148523298	5	+	27260156	K562	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.7490991828428002	[202]	[108,140,89,91]	-7	hSpCas9	negative selection	7124798
148548705	148548728	5	-	27260156	K562	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.12226496565740197	[845]	[638,774,1060,777]	1	hSpCas9	negative selection	7124799
148548696	148548719	5	+	27260156	K562	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.25109963219375453	[424]	[351,163,577,182]	-3	hSpCas9	negative selection	7189055
148636988	148637011	5	-	27260156	K562	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.14095504179842133	[575]	[450,462,697,618]	1	hSpCas9	negative selection	7189056
148548763	148548786	5	-	27260156	K562	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.44413818485813744	[509]	[730,580,483,665]	5	hSpCas9	negative selection	7189057
148523273	148523296	5	-	27260156	HT29	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.0035284002366580136	[852]	[1006,1300,729,1103]	0	hSpCas9	negative selection	7246048
148523275	148523298	5	+	27260156	HT29	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.4215504985180536	[202]	[214,126,241,152]	-6	hSpCas9	negative selection	7246049
148548705	148548728	5	-	27260156	HT29	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.021238341685457462	[845]	[1153,1010,1158,763]	0	hSpCas9	negative selection	7246050
148548696	148548719	5	+	27260156	HT29	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.2549325557204904	[424]	[808,431,652,571]	5	hSpCas9	negative selection	7310306
148636988	148637011	5	-	27260156	HT29	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.07303732907105903	[575]	[811,781,704,660]	1	hSpCas9	negative selection	7310307
148548763	148548786	5	-	27260156	HT29	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.2198105280677668	[509]	[705,735,882,575]	4	hSpCas9	negative selection	7310308
148523273	148523296	5	-	27260156	MHHES1	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.5256627753194248	[852]	[1289,920,2463,890]	8	hSpCas9	negative selection	7367299
148523275	148523298	5	+	27260156	MHHES1	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.20146660400407979	[202]	[218,89,200,257]	-4	hSpCas9	negative selection	7367300
148548705	148548728	5	-	27260156	MHHES1	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.14361204071326328	[845]	[795,1018,844,793]	-3	hSpCas9	negative selection	7367301
148548696	148548719	5	+	27260156	MHHES1	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.02468612636462386	[424]	[537,412,621,333]	0	hSpCas9	negative selection	7431557
148636988	148637011	5	-	27260156	MHHES1	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.22904394759498803	[575]	[671,558,505,492]	-4	hSpCas9	negative selection	7431558
148548763	148548786	5	-	27260156	MHHES1	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.08274132482785583	[509]	[676,526,636,583]	1	hSpCas9	negative selection	7431559
148523273	148523296	5	-	27260156	MEWO	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.30429474836539694	[852]	[733,581,639]	-6	hSpCas9	negative selection	7488550
148523275	148523298	5	+	27260156	MEWO	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.11203100868920157	[202]	[343,122,175]	2	hSpCas9	negative selection	7488551
148548705	148548728	5	-	27260156	MEWO	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.09948227621623884	[845]	[846,967,727]	2	hSpCas9	negative selection	7488552
148548696	148548719	5	+	27260156	MEWO	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.2878087137216302	[424]	[421,262,310]	-6	hSpCas9	negative selection	7552808
148636988	148637011	5	-	27260156	MEWO	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.22229594244824719	[575]	[564,391,448]	-5	hSpCas9	negative selection	7552809
148548763	148548786	5	-	27260156	MEWO	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.3774322812018692	[509]	[687,519,664]	7	hSpCas9	negative selection	7552810
148523273	148523296	5	-	27260156	LNCAPCLONEFGC	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.0358481911079912	[852]	[604,665,1108,846]	0	hSpCas9	negative selection	7609801
148523275	148523298	5	+	27260156	LNCAPCLONEFGC	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.6535499463320711	[202]	[93,133,117,120]	-7	hSpCas9	negative selection	7609802
148548705	148548728	5	-	27260156	LNCAPCLONEFGC	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.07203103568129665	[845]	[717,555,962,724]	-1	hSpCas9	negative selection	7609803
148548696	148548719	5	+	27260156	LNCAPCLONEFGC	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.29989489320325313	[424]	[322,314,188,404]	-5	hSpCas9	negative selection	7674059
148636988	148637011	5	-	27260156	LNCAPCLONEFGC	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.29017875716185254	[575]	[608,663,627,647]	4	hSpCas9	negative selection	7674060
148548763	148548786	5	-	27260156	LNCAPCLONEFGC	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.3624341386788424	[509]	[553,599,676,556]	6	hSpCas9	negative selection	7674061
148523273	148523296	5	-	27260156	PANC0327	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.37900580826992963	[852]	[382,660,605,653]	-5	hSpCas9	negative selection	7731052
148523275	148523298	5	+	27260156	PANC0327	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-1.362456615520036	[202]	[74,53,77,75]	-9	hSpCas9	negative selection	7731053
148548705	148548728	5	-	27260156	PANC0327	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.08709950241111086	[845]	[642,1158,906,424]	1	hSpCas9	negative selection	7731054
148548696	148548719	5	+	27260156	PANC0327	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.3122339585057672	[424]	[479,253,256,245]	-4	hSpCas9	negative selection	7795310
148636988	148637011	5	-	27260156	PANC0327	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.12186888830808923	[575]	[654,373,782,446]	1	hSpCas9	negative selection	7795311
148548763	148548786	5	-	27260156	PANC0327	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.10543559279141863	[509]	[354,612,343,609]	1	hSpCas9	negative selection	7795312
148523273	148523296	5	-	27260156	NCIH2009	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.13706751563577246	[852]	[1423,1192,1336]	2	hSpCas9	negative selection	7852303
148523275	148523298	5	+	27260156	NCIH2009	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.6609861821540022	[202]	[298,94,168]	-7	hSpCas9	negative selection	7852304
148548705	148548728	5	-	27260156	NCIH2009	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.6907197328366137	[845]	[963,701,575]	-7	hSpCas9	negative selection	7852305
148548696	148548719	5	+	27260156	NCIH2009	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.002929980585222647	[424]	[913,486,447]	0	hSpCas9	negative selection	7916561
148636988	148637011	5	-	27260156	NCIH2009	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.18939275309245068	[575]	[962,590,614]	-3	hSpCas9	negative selection	7916562
148548763	148548786	5	-	27260156	NCIH2009	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.41210728971830707	[509]	[1024,892,940]	5	hSpCas9	negative selection	7916563
148523273	148523296	5	-	27260156	NCIH1373	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.12448698075790476	[852]	[807,799,1170,365]	1	hSpCas9	negative selection	7973554
148523275	148523298	5	+	27260156	NCIH1373	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.7315776626145809	[202]	[48,230,85,41]	-6	hSpCas9	negative selection	7973555
148548705	148548728	5	-	27260156	NCIH1373	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.4567199377977974	[845]	[884,479,946,126]	-4	hSpCas9	negative selection	7973556
148548696	148548719	5	+	27260156	NCIH1373	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.30796689645137876	[424]	[625,467,152,83]	-3	hSpCas9	negative selection	8037812
148636988	148637011	5	-	27260156	NCIH1373	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.17413800492576098	[575]	[878,595,881,151]	1	hSpCas9	negative selection	8037813
148548763	148548786	5	-	27260156	NCIH1373	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.5282943568738572	[509]	[1101,770,888,147]	5	hSpCas9	negative selection	8037814
148523273	148523296	5	-	27260156	PATU8902	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.3279987625343519	[852]	[596,1008,974,1227]	-3	hSpCas9	negative selection	8094805
148523275	148523298	5	+	27260156	PATU8902	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-3.0863599837446305	[202]	[17,1,26,94]	-9	hSpCas9	negative selection	8094806
148548705	148548728	5	-	27260156	PATU8902	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.6125047961807123	[845]	[938,804,409,1046]	-5	hSpCas9	negative selection	8094807
148548696	148548719	5	+	27260156	PATU8902	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-1.0874241300794052	[424]	[172,270,258,433]	-7	hSpCas9	negative selection	8159063
148636988	148637011	5	-	27260156	PATU8902	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.12355866933134027	[575]	[993,426,788,707]	-1	hSpCas9	negative selection	8159064
148548763	148548786	5	-	27260156	PATU8902	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.06973511586195096	[509]	[1273,447,595,680]	0	hSpCas9	negative selection	8159065
148523273	148523296	5	-	27260156	PANC1	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.13480857099320198	[852]	[603,919,802,425]	-2	hSpCas9	negative selection	8216056
148523275	148523298	5	+	27260156	PANC1	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.2901764531847608	[202]	[202,326,180,168]	4	hSpCas9	negative selection	8216057
148548705	148548728	5	-	27260156	PANC1	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.15055442109735073	[845]	[658,679,1066,788]	2	hSpCas9	negative selection	8216058
148548696	148548719	5	+	27260156	PANC1	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.023308564652736286	[424]	[314,491,421,288]	0	hSpCas9	negative selection	8280314
148636988	148637011	5	-	27260156	PANC1	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.013276124820275459	[575]	[480,394,668,434]	0	hSpCas9	negative selection	8280315
148548763	148548786	5	-	27260156	PANC1	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.3043355911365487	[509]	[577,676,533,413]	5	hSpCas9	negative selection	8280316
148523273	148523296	5	-	27260156	PANC0813	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.04256403197832637	[852]	[1091,1047,1021,972]	0	hSpCas9	negative selection	8337307
148523275	148523298	5	+	27260156	PANC0813	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.17519916340121444	[202]	[182,190,187,275]	-3	hSpCas9	negative selection	8337308
148548705	148548728	5	-	27260156	PANC0813	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.13745306259269985	[845]	[957,872,964,825]	-2	hSpCas9	negative selection	8337309
148548696	148548719	5	+	27260156	PANC0813	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.05418309627128831	[424]	[643,421,335,531]	-1	hSpCas9	negative selection	8401565
148636988	148637011	5	-	27260156	PANC0813	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.24060543051240152	[575]	[1241,573,733,692]	4	hSpCas9	negative selection	8401566
148548763	148548786	5	-	27260156	PANC0813	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.39480410045988806	[509]	[609,791,762,957]	6	hSpCas9	negative selection	8401567
148523273	148523296	5	-	27260156	RDES	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.20199746216897008	[852]	[911,1007,1315,1341]	3	hSpCas9	negative selection	8458558
148523275	148523298	5	+	27260156	RDES	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.5342625542397796	[202]	[69,139,254,208]	-7	hSpCas9	negative selection	8458559
148548705	148548728	5	-	27260156	RDES	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.19688605131668147	[845]	[896,807,695,969]	-3	hSpCas9	negative selection	8458560
148548696	148548719	5	+	27260156	RDES	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.0679992124173735	[424]	[376,505,414,583]	-1	hSpCas9	negative selection	8522816
148636988	148637011	5	-	27260156	RDES	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.03210682945661031	[575]	[576,570,710,752]	0	hSpCas9	negative selection	8522817
148548763	148548786	5	-	27260156	RDES	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.5038461426493435	[509]	[712,821,912,890]	7	hSpCas9	negative selection	8522818
148523273	148523296	5	-	27260156	PC3	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.20769975619989023	[852]	[563,607,1117,803]	-5	hSpCas9	negative selection	8579809
148523275	148523298	5	+	27260156	PC3	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.3861779794360357	[202]	[157,171,352,444]	7	hSpCas9	negative selection	8579810
148548705	148548728	5	-	27260156	PC3	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.1604225603721594	[845]	[561,831,998,710]	-4	hSpCas9	negative selection	8579811
148548696	148548719	5	+	27260156	PC3	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.2963112784162636	[424]	[251,258,532,419]	-6	hSpCas9	negative selection	8644067
148636988	148637011	5	-	27260156	PC3	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.030989361042796204	[575]	[326,680,875,632]	0	hSpCas9	negative selection	8644068
148548763	148548786	5	-	27260156	PC3	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.03448301263170324	[509]	[356,635,598,529]	0	hSpCas9	negative selection	8644069
148523273	148523296	5	-	27260156	PATU8988T	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.05579306488166813	[852]	[720,1055,615,806]	-1	hSpCas9	negative selection	8701060
148523275	148523298	5	+	27260156	PATU8988T	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.5015646221811463	[202]	[175,221,51,110]	-7	hSpCas9	negative selection	8701061
148548705	148548728	5	-	27260156	PATU8988T	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.02474441964633911	[845]	[793,867,803,866]	0	hSpCas9	negative selection	8701062
148548696	148548719	5	+	27260156	PATU8988T	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.17438359324488384	[424]	[243,718,448,465]	3	hSpCas9	negative selection	8765318
148636988	148637011	5	-	27260156	PATU8988T	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.10249556864764064	[575]	[719,547,565,547]	1	hSpCas9	negative selection	8765319
148548763	148548786	5	-	27260156	PATU8988T	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.04347486242230526	[509]	[837,393,429,346]	0	hSpCas9	negative selection	8765320
148523273	148523296	5	-	27260156	T47D	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.027891426456703394	[852]	[1100,908,920,1135]	0	hSpCas9	negative selection	8822311
148523275	148523298	5	+	27260156	T47D	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.10145410054890158	[202]	[213,186,259,222]	-2	hSpCas9	negative selection	8822312
148548705	148548728	5	-	27260156	T47D	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.007205367193085732	[845]	[942,979,956,1085]	0	hSpCas9	negative selection	8822313
148548696	148548719	5	+	27260156	T47D	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.06163002774065854	[424]	[527,532,463,541]	1	hSpCas9	negative selection	8886569
148636988	148637011	5	-	27260156	T47D	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.1257806345948892	[575]	[806,569,796,768]	2	hSpCas9	negative selection	8886570
148548763	148548786	5	-	27260156	T47D	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.13528793118013938	[509]	[611,718,590,683]	3	hSpCas9	negative selection	8886571
148523273	148523296	5	-	27260156	SU8686	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.3175463350357838	[852]	[800,984,1233,1264]	5	hSpCas9	negative selection	8943562
148523275	148523298	5	+	27260156	SU8686	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.4444657380944972	[202]	[135,109,156,202]	-6	hSpCas9	negative selection	8943563
148548705	148548728	5	-	27260156	SU8686	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.18753478868277518	[845]	[785,531,727,949]	-3	hSpCas9	negative selection	8943564
148548696	148548719	5	+	27260156	SU8686	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.30245497567232815	[424]	[301,246,402,447]	-5	hSpCas9	negative selection	9007820
148636988	148637011	5	-	27260156	SU8686	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.018256960057802807	[575]	[601,473,571,619]	0	hSpCas9	negative selection	9007821
148548763	148548786	5	-	27260156	SU8686	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.32769596581433247	[509]	[530,660,432,964]	5	hSpCas9	negative selection	9007822
148523273	148523296	5	-	27260156	SKES1	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.12795693444870015	[852]	[889,750,745,736]	-3	hSpCas9	negative selection	9064813
148523275	148523298	5	+	27260156	SKES1	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	0.10580856914306214	[202]	[253,213,216,191]	2	hSpCas9	negative selection	9064814
148548705	148548728	5	-	27260156	SKES1	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.20017353337631072	[845]	[918,1076,924,954]	4	hSpCas9	negative selection	9064815
148548696	148548719	5	+	27260156	SKES1	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.030894294699674363	[424]	[359,542,354,406]	0	hSpCas9	negative selection	9129071
148636988	148637011	5	-	27260156	SKES1	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.1625613185101657	[575]	[596,871,653,482]	3	hSpCas9	negative selection	9129072
148548763	148548786	5	-	27260156	SKES1	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.26872492295793526	[509]	[675,667,557,564]	5	hSpCas9	negative selection	9129073
148523273	148523296	5	-	27260156	TOV112D	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.3126982405115398	[852]	[578,619,678,841]	-6	hSpCas9	negative selection	9186064
148523275	148523298	5	+	27260156	TOV112D	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.7086698859667981	[202]	[110,112,163,105]	-8	hSpCas9	negative selection	9186065
148548705	148548728	5	-	27260156	TOV112D	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.13542260772072612	[845]	[763,961,756,650]	-3	hSpCas9	negative selection	9186066
148548696	148548719	5	+	27260156	TOV112D	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	0.13452916856821268	[424]	[538,487,333,516]	2	hSpCas9	negative selection	9250322
148636988	148637011	5	-	27260156	TOV112D	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	-0.11575061694030961	[575]	[562,705,514,393]	-2	hSpCas9	negative selection	9250323
148548763	148548786	5	-	27260156	TOV112D	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.2685777908048749	[509]	[539,845,485,637]	5	hSpCas9	negative selection	9250324
148523273	148523296	5	-	27260156	TC71	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	-0.09420509014195688	[852]	[805,832,868,922]	-2	hSpCas9	negative selection	9307315
148523275	148523298	5	+	27260156	TC71	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.1899526656427024	[202]	[185,202,216,153]	-5	hSpCas9	negative selection	9307316
148548705	148548728	5	-	27260156	TC71	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	-0.04842809918913926	[845]	[711,833,997,968]	-1	hSpCas9	negative selection	9307317
148548696	148548719	5	+	27260156	TC71	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.19017947579416264	[424]	[374,476,411,328]	-5	hSpCas9	negative selection	9371573
148636988	148637011	5	-	27260156	TC71	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.01145232949404823	[575]	[519,786,559,626]	0	hSpCas9	negative selection	9371574
148548763	148548786	5	-	27260156	TC71	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	-0.00397278998052103	[509]	[483,588,557,550]	0	hSpCas9	negative selection	9371575
148523273	148523296	5	-	27260156	TC32	viability	TCTGCGCATCGCATTAATGCTGG	HTR4	ENSG00000164270	0.0029140857329581493	[852]	[815,589,1066,816]	0	hSpCas9	negative selection	9428566
148523275	148523298	5	+	27260156	TC32	viability	AGCATTAATGCGATGCGCAGAGG	HTR4	ENSG00000164270	-0.3103602146058362	[202]	[196,168,105,109]	-5	hSpCas9	negative selection	9428567
148548705	148548728	5	-	27260156	TC32	viability	TCTGGACGTCCTGCTCACAACGG	HTR4	ENSG00000164270	0.04657065134825156	[845]	[823,625,1024,870]	0	hSpCas9	negative selection	9428568
148548696	148548719	5	+	27260156	TC32	viability	AAATCGATGCCGTTGTGAGCAGG	HTR4	ENSG00000164270	-0.07930140223973059	[424]	[339,323,509,361]	-1	hSpCas9	negative selection	9492824
148636988	148637011	5	-	27260156	TC32	viability	ACAAACTTGATGCTAATGTGAGG	HTR4	ENSG00000164270	0.12628975233147322	[575]	[592,424,825,586]	2	hSpCas9	negative selection	9492825
148548763	148548786	5	-	27260156	TC32	viability	TTGAGCTGGTTCAAGACATCTGG	HTR4	ENSG00000164270	0.3809703186168387	[509]	[491,516,840,708]	6	hSpCas9	negative selection	9492826
148509619	148509642	5	+	27869803	HPAFII	viability after 27 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.17946927283251768	[149]	[1,125,NaN]	-1	hSpCas9	negative selection	9590540
148520939	148520962	5	-	27869803	HPAFII	viability after 27 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	-0.7735570606548756	[46]	[14,13,NaN]	-5	hSpCas9	negative selection	9590541
148523277	148523300	5	+	27869803	HPAFII	viability after 27 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.2671354336317897	[246]	[224,98,NaN]	2	hSpCas9	negative selection	9590542
148548775	148548798	5	+	27869803	HPAFII	viability after 27 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.31478485727196914	[382]	[106,369,NaN]	2	hSpCas9	negative selection	9590543
148550228	148550251	5	-	27869803	HPAFII	viability after 27 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.04510745994774236	[240]	[133,127,NaN]	0	hSpCas9	negative selection	9590544
148665482	148665505	5	+	27869803	HPAFII	viability after 27 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.5975687892352186	[300]	[305,183,NaN]	5	hSpCas9	negative selection	9590546
148509619	148509642	5	+	27869803	HPAFII	viability after 15 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.7085174067547928	[149]	[118,85,NaN]	-6	hSpCas9	negative selection	9672989
148520939	148520962	5	-	27869803	HPAFII	viability after 15 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	0.22563435624107786	[46]	[26,78,NaN]	2	hSpCas9	negative selection	9672990
148523277	148523300	5	+	27869803	HPAFII	viability after 15 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.1582739014468519	[246]	[524,153,NaN]	1	hSpCas9	negative selection	9672991
148548775	148548798	5	+	27869803	HPAFII	viability after 15 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.47520438544494326	[382]	[586,562,NaN]	5	hSpCas9	negative selection	9672992
148550228	148550251	5	-	27869803	HPAFII	viability after 15 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.5372031486755156	[240]	[521,284,NaN]	6	hSpCas9	negative selection	9672993
148665482	148665505	5	+	27869803	HPAFII	viability after 15 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.27414123346603336	[300]	[487,330,NaN]	3	hSpCas9	negative selection	9672995
148509619	148509642	5	+	27869803	ASPC1	viability after 36 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.07056987424553551	[377]	[165,199,36]	0	hSpCas9	negative selection	9755438
148520939	148520962	5	-	27869803	ASPC1	viability after 36 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	-0.027588417732969273	[128]	[83,24,30]	0	hSpCas9	negative selection	9755439
148523277	148523300	5	+	27869803	ASPC1	viability after 36 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.241841869863807	[781]	[406,263,306]	2	hSpCas9	negative selection	9755440
148548775	148548798	5	+	27869803	ASPC1	viability after 36 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.7610450342802573	[827]	[278,904,302]	7	hSpCas9	negative selection	9755441
148550228	148550251	5	-	27869803	ASPC1	viability after 36 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.2209433960431389	[648]	[189,175,209]	-2	hSpCas9	negative selection	9755442
148665482	148665505	5	+	27869803	ASPC1	viability after 36 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.6185072404561003	[779]	[406,420,418]	6	hSpCas9	negative selection	9755444
148509619	148509642	5	+	27869803	PATU8988S	viability after 35 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.45794861414136134	[314]	[69,278,NaN]	5	hSpCas9	negative selection	9837887
148520939	148520962	5	-	27869803	PATU8988S	viability after 35 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	1.1889802674333545	[103]	[93,96,NaN]	9	hSpCas9	negative selection	9837888
148523277	148523300	5	+	27869803	PATU8988S	viability after 35 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.8765479625257345	[520]	[274,495,NaN]	8	hSpCas9	negative selection	9837889
148548775	148548798	5	+	27869803	PATU8988S	viability after 35 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.5234414339505664	[645]	[361,385,NaN]	6	hSpCas9	negative selection	9837890
148550228	148550251	5	-	27869803	PATU8988S	viability after 35 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.2945085123276584	[586]	[269,309,NaN]	3	hSpCas9	negative selection	9837891
148665482	148665505	5	+	27869803	PATU8988S	viability after 35 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.43708062573017487	[769]	[575,262,NaN]	5	hSpCas9	negative selection	9837893
148509619	148509642	5	+	27869803	PATU8988S	viability after 31 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	0.23664622465425256	[314]	[114,189,NaN]	3	hSpCas9	negative selection	9920336
148520939	148520962	5	-	27869803	PATU8988S	viability after 31 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	-0.27797158434010827	[103]	[42,22,NaN]	-3	hSpCas9	negative selection	9920337
148523277	148523300	5	+	27869803	PATU8988S	viability after 31 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.4150225537638129	[520]	[232,332,NaN]	5	hSpCas9	negative selection	9920338
148548775	148548798	5	+	27869803	PATU8988S	viability after 31 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.3973469315450826	[645]	[267,429,NaN]	5	hSpCas9	negative selection	9920339
148550228	148550251	5	-	27869803	PATU8988S	viability after 31 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	0.2259566900134513	[586]	[216,345,NaN]	3	hSpCas9	negative selection	9920340
148665482	148665505	5	+	27869803	PATU8988S	viability after 31 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.3128072257110018	[769]	[438,307,NaN]	4	hSpCas9	negative selection	9920342
148509619	148509642	5	+	27869803	HPAFII	viability after 35 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-1.0039137715699735	[149]	[3,75,NaN]	-5	hSpCas9	negative selection	10002785
148520939	148520962	5	-	27869803	HPAFII	viability after 35 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	-0.5107582473183632	[46]	[3,30,NaN]	-3	hSpCas9	negative selection	10002786
148523277	148523300	5	+	27869803	HPAFII	viability after 35 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.47443458896398166	[246]	[224,115,NaN]	3	hSpCas9	negative selection	10002787
148548775	148548798	5	+	27869803	HPAFII	viability after 35 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.7837554483111153	[382]	[179,506,NaN]	5	hSpCas9	negative selection	10002788
148550228	148550251	5	-	27869803	HPAFII	viability after 35 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.1557273325560584	[240]	[93,126,NaN]	-1	hSpCas9	negative selection	10002789
148665482	148665505	5	+	27869803	HPAFII	viability after 35 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.5113071622666189	[300]	[251,177,NaN]	3	hSpCas9	negative selection	10002791
148509619	148509642	5	+	27869803	HPAFII	viability after 31 days	AATTGATATAGCCGAGCCAGAGG	HTR4	ENSG00000164270	-0.6774773694447498	[149]	[10,97,NaN]	-4	hSpCas9	negative selection	10085234
148520939	148520962	5	-	27869803	HPAFII	viability after 31 days	AAGGAGTCTAAACCAAGGCCTGG	HTR4	ENSG00000164270	-0.1002124013556922	[46]	[26,21,NaN]	0	hSpCas9	negative selection	10085235
148523277	148523300	5	+	27869803	HPAFII	viability after 31 days	CATTAATGCGATGCGCAGAGGGG	HTR4	ENSG00000164270	0.3920057008547041	[246]	[268,86,NaN]	3	hSpCas9	negative selection	10085236
148548775	148548798	5	+	27869803	HPAFII	viability after 31 days	AACCAGCTCAATGGCACCAAAGG	HTR4	ENSG00000164270	0.29621338871860436	[382]	[94,447,NaN]	2	hSpCas9	negative selection	10085237
148550228	148550251	5	-	27869803	HPAFII	viability after 31 days	TTTCGGGTCAGTGGAGAAGGTGG	HTR4	ENSG00000164270	-0.15827224796911543	[240]	[147,91,NaN]	-1	hSpCas9	negative selection	10085238
148665482	148665505	5	+	27869803	HPAFII	viability after 31 days	TCACCTCCAGGCACGACAGCTGG	HTR4	ENSG00000164270	0.1922085601836362	[300]	[192,192,NaN]	1	hSpCas9	negative selection	10085240
148509932	148509955	5	+	28162770	P31FUJ	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	0.0419140064670505	[204]	[247]	0	hSpCas9	negative selection	10172054
148509703	148509726	5	+	28162770	P31FUJ	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	0.6409340229394488	[178]	[327]	7	hSpCas9	negative selection	10172055
148550162	148550185	5	-	28162770	P31FUJ	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.2977125122844011	[116]	[168]	3	hSpCas9	negative selection	10172056
148509643	148509666	5	+	28162770	P31FUJ	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	-0.00030919310896082575	[182]	[214]	0	hSpCas9	negative selection	10172057
148509545	148509568	5	+	28162770	P31FUJ	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.7444777190855378	[159]	[314]	8	hSpCas9	negative selection	10172058
148509532	148509555	5	+	28162770	P31FUJ	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.49482552517249134	[185]	[307]	5	hSpCas9	negative selection	10172059
148550252	148550275	5	-	28162770	P31FUJ	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.2735355306659726	[772]	[1097]	3	hSpCas9	negative selection	10172060
148550204	148550227	5	-	28162770	P31FUJ	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.35595686439485674	[505]	[760]	4	hSpCas9	negative selection	10172061
148548750	148548773	5	-	28162770	P31FUJ	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.2733831829226605	[68]	[97]	3	hSpCas9	negative selection	10172062
148509806	148509829	5	+	28162770	P31FUJ	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.29490912050428386	[316]	[456]	3	hSpCas9	negative selection	10172063
148509932	148509955	5	+	28162770	TF1	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	NaN	[NaN]	[510]	1	hSpCas9	negative selection	10341420
148509703	148509726	5	+	28162770	TF1	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	NaN	[NaN]	[163]	1	hSpCas9	negative selection	10341421
148550162	148550185	5	-	28162770	TF1	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	NaN	[NaN]	[338]	1	hSpCas9	negative selection	10341422
148509643	148509666	5	+	28162770	TF1	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10341423
148509545	148509568	5	+	28162770	TF1	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	NaN	[NaN]	[130]	1	hSpCas9	negative selection	10341424
148509532	148509555	5	+	28162770	TF1	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10341425
148550252	148550275	5	-	28162770	TF1	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	NaN	[NaN]	[971]	1	hSpCas9	negative selection	10341426
148550204	148550227	5	-	28162770	TF1	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	NaN	[NaN]	[596]	1	hSpCas9	negative selection	10341427
148548750	148548773	5	-	28162770	TF1	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10341428
148509806	148509829	5	+	28162770	TF1	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	NaN	[NaN]	[379]	1	hSpCas9	negative selection	10341429
148509932	148509955	5	+	28162770	SKM1	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	-0.385902583215332	[67]	[91]	-3	hSpCas9	negative selection	10510786
148509703	148509726	5	+	28162770	SKM1	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.27451390271951204	[38]	[56]	-2	hSpCas9	negative selection	10510787
148550162	148550185	5	-	28162770	SKM1	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.4999263968653567	[35]	[89]	5	hSpCas9	negative selection	10510788
148509643	148509666	5	+	28162770	SKM1	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.2849135058945063	[51]	[111]	2	hSpCas9	negative selection	10510789
148509545	148509568	5	+	28162770	SKM1	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.05869937360565011	[62]	[115]	0	hSpCas9	negative selection	10510790
148509532	148509555	5	+	28162770	SKM1	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	-0.5390677347505068	[59]	[72]	-4	hSpCas9	negative selection	10510791
148550252	148550275	5	-	28162770	SKM1	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	-0.14709707198805066	[170]	[272]	-1	hSpCas9	negative selection	10510792
148550204	148550227	5	-	28162770	SKM1	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.4266222648876221	[108]	[258]	4	hSpCas9	negative selection	10510793
148548750	148548773	5	-	28162770	SKM1	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-0.7675539139996292	[25]	[26]	-5	hSpCas9	negative selection	10510794
148509806	148509829	5	+	28162770	SKM1	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	-0.08828176335945337	[88]	[147]	0	hSpCas9	negative selection	10510795
148509932	148509955	5	+	28162770	SKM1	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	-0.385902583215332	[67]	[91]	-3	hSpCas9	negative selection	10680152
148509703	148509726	5	+	28162770	SKM1	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.27451390271951204	[38]	[56]	-2	hSpCas9	negative selection	10680153
148550162	148550185	5	-	28162770	SKM1	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.4999263968653567	[35]	[89]	5	hSpCas9	negative selection	10680154
148509643	148509666	5	+	28162770	SKM1	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.2849135058945063	[51]	[111]	2	hSpCas9	negative selection	10680155
148509545	148509568	5	+	28162770	SKM1	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.05869937360565011	[62]	[115]	0	hSpCas9	negative selection	10680156
148509532	148509555	5	+	28162770	SKM1	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	-0.5390677347505068	[59]	[72]	-4	hSpCas9	negative selection	10680157
148550252	148550275	5	-	28162770	SKM1	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	-0.14709707198805066	[170]	[272]	-1	hSpCas9	negative selection	10680158
148550204	148550227	5	-	28162770	SKM1	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.4266222648876221	[108]	[258]	4	hSpCas9	negative selection	10680159
148548750	148548773	5	-	28162770	SKM1	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-0.7675539139996292	[25]	[26]	-5	hSpCas9	negative selection	10680160
148509806	148509829	5	+	28162770	SKM1	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	-0.08828176335945337	[88]	[147]	0	hSpCas9	negative selection	10680161
148509932	148509955	5	+	28162770	PL21	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	-0.5664968463532287	[261]	[76]	-4	hSpCas9	negative selection	10849518
148509703	148509726	5	+	28162770	PL21	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	1.806475766003043	[133]	[203]	9	hSpCas9	negative selection	10849519
148550162	148550185	5	-	28162770	PL21	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	1.120216070192371	[166]	[157]	8	hSpCas9	negative selection	10849520
148509643	148509666	5	+	28162770	PL21	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	-0.06856354143116583	[305]	[126]	0	hSpCas9	negative selection	10849521
148509545	148509568	5	+	28162770	PL21	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.8634481669302173	[220]	[174]	7	hSpCas9	negative selection	10849522
148509532	148509555	5	+	28162770	PL21	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	-0.47502069520341433	[197]	[61]	-3	hSpCas9	negative selection	10849523
148550252	148550275	5	-	28162770	PL21	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.311170926878064	[449]	[242]	2	hSpCas9	negative selection	10849524
148550204	148550227	5	-	28162770	PL21	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.782219606677355	[333]	[249]	6	hSpCas9	negative selection	10849525
148548750	148548773	5	-	28162770	PL21	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.6045298695686555	[67]	[44]	5	hSpCas9	negative selection	10849526
148509806	148509829	5	+	28162770	PL21	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	-0.32742057518691414	[270]	[93]	-2	hSpCas9	negative selection	10849527
148509932	148509955	5	+	28162770	P31FUJ	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	0.0419140064670505	[204]	[247]	0	hSpCas9	negative selection	11018884
148509703	148509726	5	+	28162770	P31FUJ	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	0.6409340229394488	[178]	[327]	7	hSpCas9	negative selection	11018885
148550162	148550185	5	-	28162770	P31FUJ	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.2977125122844011	[116]	[168]	3	hSpCas9	negative selection	11018886
148509643	148509666	5	+	28162770	P31FUJ	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	-0.00030919310896082575	[182]	[214]	0	hSpCas9	negative selection	11018887
148509545	148509568	5	+	28162770	P31FUJ	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.7444777190855378	[159]	[314]	8	hSpCas9	negative selection	11018888
148509532	148509555	5	+	28162770	P31FUJ	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.49482552517249134	[185]	[307]	5	hSpCas9	negative selection	11018889
148550252	148550275	5	-	28162770	P31FUJ	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.2735355306659726	[772]	[1097]	3	hSpCas9	negative selection	11018890
148550204	148550227	5	-	28162770	P31FUJ	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.35595686439485674	[505]	[760]	4	hSpCas9	negative selection	11018891
148548750	148548773	5	-	28162770	P31FUJ	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.2733831829226605	[68]	[97]	3	hSpCas9	negative selection	11018892
148509806	148509829	5	+	28162770	P31FUJ	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.29490912050428386	[316]	[456]	3	hSpCas9	negative selection	11018893
148509932	148509955	5	+	28162770	OCIAML5	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	0.28928927838154433	[135]	[299]	2	hSpCas9	negative selection	11188250
148509703	148509726	5	+	28162770	OCIAML5	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	1.2120637665557186	[54]	[229]	8	hSpCas9	negative selection	11188251
148550162	148550185	5	-	28162770	OCIAML5	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.5105035085207112	[55]	[143]	4	hSpCas9	negative selection	11188252
148509643	148509666	5	+	28162770	OCIAML5	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.591922302110976	[110]	[301]	5	hSpCas9	negative selection	11188253
148509545	148509568	5	+	28162770	OCIAML5	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.46716237442241004	[106]	[266]	4	hSpCas9	negative selection	11188254
148509532	148509555	5	+	28162770	OCIAML5	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	1.013283902441221	[100]	[367]	8	hSpCas9	negative selection	11188255
148550252	148550275	5	-	28162770	OCIAML5	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.5386142152776563	[335]	[880]	5	hSpCas9	negative selection	11188256
148550204	148550227	5	-	28162770	OCIAML5	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	-0.26253134035301673	[314]	[473]	-2	hSpCas9	negative selection	11188257
148548750	148548773	5	-	28162770	OCIAML5	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-0.28728195208047125	[47]	[70]	-2	hSpCas9	negative selection	11188258
148509806	148509829	5	+	28162770	OCIAML5	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.551096828126555	[182]	[483]	5	hSpCas9	negative selection	11188259
148509932	148509955	5	+	28162770	EOL1	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	-0.15599565574001434	[441]	[208]	-1	hSpCas9	negative selection	11357616
148509703	148509726	5	+	28162770	EOL1	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	0.9483945135249022	[179]	[182]	7	hSpCas9	negative selection	11357617
148550162	148550185	5	-	28162770	EOL1	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	-0.14920056841077795	[300]	[142]	-1	hSpCas9	negative selection	11357618
148509643	148509666	5	+	28162770	EOL1	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.805376070592857	[390]	[359]	7	hSpCas9	negative selection	11357619
148509545	148509568	5	+	28162770	EOL1	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	-0.2978446497659134	[272]	[116]	-2	hSpCas9	negative selection	11357620
148509532	148509555	5	+	28162770	EOL1	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.14752392548257273	[352]	[205]	1	hSpCas9	negative selection	11357621
148550252	148550275	5	-	28162770	EOL1	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.5802683658370682	[682]	[537]	5	hSpCas9	negative selection	11357622
148550204	148550227	5	-	28162770	EOL1	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	1.0100439918521409	[474]	[503]	8	hSpCas9	negative selection	11357623
148548750	148548773	5	-	28162770	EOL1	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-0.3049340745522331	[67]	[28]	-2	hSpCas9	negative selection	11357624
148509806	148509829	5	+	28162770	EOL1	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	-0.4159960014841747	[389]	[153]	-3	hSpCas9	negative selection	11357625
148509932	148509955	5	+	28162770	MOLM13	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	1.480637874286567	[337]	[681]	9	hSpCas9	negative selection	11526982
148509703	148509726	5	+	28162770	MOLM13	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.3235239966440038	[179]	[103]	-2	hSpCas9	negative selection	11526983
148550162	148550185	5	-	28162770	MOLM13	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	1.5146835930235198	[181]	[375]	9	hSpCas9	negative selection	11526984
148509643	148509666	5	+	28162770	MOLM13	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.8733408319942247	[301]	[399]	6	hSpCas9	negative selection	11526985
148509545	148509568	5	+	28162770	MOLM13	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.24653300696065555	[231]	[198]	1	hSpCas9	negative selection	11526986
148509532	148509555	5	+	28162770	MOLM13	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.4816512827890632	[312]	[315]	3	hSpCas9	negative selection	11526987
148550252	148550275	5	-	28162770	MOLM13	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.2274157785115678	[735]	[622]	1	hSpCas9	negative selection	11526988
148550204	148550227	5	-	28162770	MOLM13	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.29066212938105584	[717]	[634]	2	hSpCas9	negative selection	11526989
148548750	148548773	5	-	28162770	MOLM13	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-0.4286060427015612	[120]	[64]	-3	hSpCas9	negative selection	11526990
148509806	148509829	5	+	28162770	MOLM13	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.16122804331052687	[375]	[303]	1	hSpCas9	negative selection	11526991
148509932	148509955	5	+	28162770	HEL	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	1.00796043766147	[301]	[388]	8	hSpCas9	negative selection	11696348
148509703	148509726	5	+	28162770	HEL	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	1.2164740772982592	[128]	[191]	9	hSpCas9	negative selection	11696349
148550162	148550185	5	-	28162770	HEL	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.7502232586667623	[180]	[194]	6	hSpCas9	negative selection	11696350
148509643	148509666	5	+	28162770	HEL	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.8822047666957464	[215]	[254]	7	hSpCas9	negative selection	11696351
148509545	148509568	5	+	28162770	HEL	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.08392861913516936	[245]	[166]	0	hSpCas9	negative selection	11696352
148509532	148509555	5	+	28162770	HEL	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.8014365780194155	[300]	[335]	7	hSpCas9	negative selection	11696353
148550252	148550275	5	-	28162770	HEL	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.1954917200770072	[618]	[453]	1	hSpCas9	negative selection	11696354
148550204	148550227	5	-	28162770	HEL	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.5461444337615649	[524]	[490]	4	hSpCas9	negative selection	11696355
148548750	148548773	5	-	28162770	HEL	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.12190666869891653	[65]	[45]	1	hSpCas9	negative selection	11696356
148509806	148509829	5	+	28162770	HEL	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.5013190774131341	[331]	[300]	4	hSpCas9	negative selection	11696357
148509932	148509955	5	+	28162770	MV411	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	-0.3342938286753678	[222]	[148]	-3	hSpCas9	negative selection	11865714
148509703	148509726	5	+	28162770	MV411	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.24476780901852846	[127]	[90]	-2	hSpCas9	negative selection	11865715
148550162	148550185	5	-	28162770	MV411	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	1.6690777848858662	[108]	[291]	9	hSpCas9	negative selection	11865716
148509643	148509666	5	+	28162770	MV411	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.5246161389368391	[202]	[245]	5	hSpCas9	negative selection	11865717
148509545	148509568	5	+	28162770	MV411	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	1.1636059599793047	[123]	[233]	9	hSpCas9	negative selection	11865718
148509532	148509555	5	+	28162770	MV411	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	-0.0705325305359037	[181]	[145]	0	hSpCas9	negative selection	11865719
148550252	148550275	5	-	28162770	MV411	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	-0.09732125248547252	[413]	[325]	0	hSpCas9	negative selection	11865720
148550204	148550227	5	-	28162770	MV411	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.06735593430429176	[391]	[345]	0	hSpCas9	negative selection	11865721
148548750	148548773	5	-	28162770	MV411	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-1.8166927866369402	[45]	[10]	-8	hSpCas9	negative selection	11865722
148509806	148509829	5	+	28162770	MV411	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	-0.7109147518587334	[238]	[122]	-5	hSpCas9	negative selection	11865723
148509932	148509955	5	+	28162770	MONOMAC1	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	0.7747294722115022	[128]	[252]	7	hSpCas9	negative selection	12035080
148509703	148509726	5	+	28162770	MONOMAC1	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.625880145863428	[104]	[77]	-5	hSpCas9	negative selection	12035081
148550162	148550185	5	-	28162770	MONOMAC1	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	0.14809863898913386	[110]	[140]	1	hSpCas9	negative selection	12035082
148509643	148509666	5	+	28162770	MONOMAC1	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.6076389748021692	[153]	[268]	6	hSpCas9	negative selection	12035083
148509545	148509568	5	+	28162770	MONOMAC1	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.05450191993641065	[104]	[124]	0	hSpCas9	negative selection	12035084
148509532	148509555	5	+	28162770	MONOMAC1	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	-0.1400059020231747	[123]	[128]	-1	hSpCas9	negative selection	12035085
148550252	148550275	5	-	28162770	MONOMAC1	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.056719745186229575	[389]	[464]	0	hSpCas9	negative selection	12035086
148550204	148550227	5	-	28162770	MONOMAC1	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.3233536523655185	[197]	[283]	3	hSpCas9	negative selection	12035087
148548750	148548773	5	-	28162770	MONOMAC1	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	0.9404666766903811	[29]	[65]	8	hSpCas9	negative selection	12035088
148509806	148509829	5	+	28162770	MONOMAC1	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.4488546523039342	[169]	[265]	4	hSpCas9	negative selection	12035089
148509932	148509955	5	+	28162770	OCIAML2	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	1.6342851849675273	[28]	[498]	9	hSpCas9	negative selection	12204446
148509703	148509726	5	+	28162770	OCIAML2	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.26117645961321145	[31]	[147]	-2	hSpCas9	negative selection	12204447
148550162	148550185	5	-	28162770	OCIAML2	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	-0.18522760637991278	[31]	[155]	-1	hSpCas9	negative selection	12204448
148509643	148509666	5	+	28162770	OCIAML2	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	0.7115735059785878	[38]	[353]	7	hSpCas9	negative selection	12204449
148509545	148509568	5	+	28162770	OCIAML2	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.19525267086256237	[51]	[329]	1	hSpCas9	negative selection	12204450
148509532	148509555	5	+	28162770	OCIAML2	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	0.5935005121775545	[32]	[275]	6	hSpCas9	negative selection	12204451
148550252	148550275	5	-	28162770	OCIAML2	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	1.0742794259585557	[69]	[816]	8	hSpCas9	negative selection	12204452
148550204	148550227	5	-	28162770	OCIAML2	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	0.7884210666731348	[67]	[650]	7	hSpCas9	negative selection	12204453
148548750	148548773	5	-	28162770	OCIAML2	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-0.5637392296336425	[15]	[59]	-4	hSpCas9	negative selection	12204454
148509806	148509829	5	+	28162770	OCIAML2	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.4436403007319547	[38]	[293]	4	hSpCas9	negative selection	12204455
148509932	148509955	5	+	28162770	OCIAML3	viability	GGCCACCACAGAGCAGGTGATGG	HTR4	ENSG00000164270	-0.8702174349056901	[65]	[108]	-6	hSpCas9	negative selection	12373812
148509703	148509726	5	+	28162770	OCIAML3	viability	CAAAGAATGGTGCCCAGCAGAGG	HTR4	ENSG00000164270	-0.10572115901468071	[35]	[100]	-1	hSpCas9	negative selection	12373813
148550162	148550185	5	-	28162770	OCIAML3	viability	GGGGAACCTGCTGGTGATGGTGG	HTR4	ENSG00000164270	-0.3529995408203683	[43]	[103]	-3	hSpCas9	negative selection	12373814
148509643	148509666	5	+	28162770	OCIAML3	viability	AAGCAGTCCACACCTGCCCAGGG	HTR4	ENSG00000164270	-0.8808887881123247	[60]	[99]	-6	hSpCas9	negative selection	12373815
148509545	148509568	5	+	28162770	OCIAML3	viability	ACAGCAGAGGATGATGAGGAAGG	HTR4	ENSG00000164270	0.4808795713068287	[60]	[256]	4	hSpCas9	negative selection	12373816
148509532	148509555	5	+	28162770	OCIAML3	viability	AGCGCTCATCATCACAGCAGAGG	HTR4	ENSG00000164270	-0.1896173852448279	[50]	[134]	-1	hSpCas9	negative selection	12373817
148550252	148550275	5	-	28162770	OCIAML3	viability	TGTGTCTTTCAGTTCTGAGGAGG	HTR4	ENSG00000164270	0.37893334745141605	[147]	[580]	3	hSpCas9	negative selection	12373818
148550204	148550227	5	-	28162770	OCIAML3	viability	GCTGCTCACGTTTCTCTCGACGG	HTR4	ENSG00000164270	-0.2251785704677728	[114]	[296]	-2	hSpCas9	negative selection	12373819
148548750	148548773	5	-	28162770	OCIAML3	viability	AGACATCTGGATTTATGGGGAGG	HTR4	ENSG00000164270	-0.4944719667732489	[13]	[29]	-4	hSpCas9	negative selection	12373820
148509806	148509829	5	+	28162770	OCIAML3	viability	CGACTGAGGCCTGCTCTCGGAGG	HTR4	ENSG00000164270	0.5086780236504008	[60]	[261]	5	hSpCas9	negative selection	12373821