Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:23308
• Symbol:ICOSLG
• Description:inducible T cell costimulator ligand

DataSource: http://genomecrispr.dkfz.de/#!/results/ICOSLG

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
5026287	5026310	21	+	26472758	Jiyoye	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-1.3033180012991417	[71]	[21]	-7	hSpCas9	negative selection	75679
44237188	44237211	21	-	26472758	Jiyoye	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-1.3033180012991417	[71]	[21]	-7	hSpCas9	negative selection	75680
5032144	5032167	21	+	26472758	Jiyoye	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	-1.4803498892357139	[73]	[19]	-7	hSpCas9	negative selection	75681
44231331	44231354	21	-	26472758	Jiyoye	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	-1.4803498892357139	[73]	[19]	-7	hSpCas9	negative selection	75682
44236960	44236983	21	+	26472758	Jiyoye	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	1.1914466904504364	[17]	[30]	7	hSpCas9	negative selection	75683
5026515	5026538	21	-	26472758	Jiyoye	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	1.1914466904504364	[17]	[30]	7	hSpCas9	negative selection	75684
44235321	44235344	21	+	26472758	Jiyoye	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	1.5621500414822145	[96]	[215]	8	hSpCas9	negative selection	75685
5028154	5028177	21	-	26472758	Jiyoye	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	1.5621500414822145	[96]	[215]	8	hSpCas9	negative selection	75686
5026389	5026412	21	+	26472758	Jiyoye	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	1.2651563766334455	[95]	[173]	7	hSpCas9	negative selection	75687
44237086	44237109	21	-	26472758	Jiyoye	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	1.2651563766334455	[95]	[173]	7	hSpCas9	negative selection	75688
44235502	44235525	21	+	26472758	Jiyoye	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	2.393754865743552	[26]	[106]	9	hSpCas9	negative selection	75689
5027973	5027996	21	-	26472758	Jiyoye	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	2.393754865743552	[26]	[106]	9	hSpCas9	negative selection	75690
44235428	44235451	21	-	26472758	Jiyoye	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.06117952665668114	[135]	[106]	0	hSpCas9	negative selection	75691
5028047	5028070	21	+	26472758	Jiyoye	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.06117952665668114	[135]	[106]	0	hSpCas9	negative selection	75692
5028104	5028127	21	+	26472758	Jiyoye	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.05040781273905537	[194]	[141]	0	hSpCas9	negative selection	75693
44235371	44235394	21	-	26472758	Jiyoye	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.05040781273905537	[194]	[141]	0	hSpCas9	negative selection	75694
44236985	44237008	21	+	26472758	Jiyoye	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	5.86660700014317	[0]	[43]	9	hSpCas9	negative selection	75695
5026490	5026513	21	-	26472758	Jiyoye	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	5.86660700014317	[0]	[43]	9	hSpCas9	negative selection	75696
5026575	5026598	21	+	26472758	Jiyoye	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	-0.25029961899965064	[152]	[96]	-2	hSpCas9	negative selection	75697
44236900	44236923	21	-	26472758	Jiyoye	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	-0.25029961899965064	[152]	[96]	-2	hSpCas9	negative selection	75698
5026287	5026310	21	+	26472758	KBM7	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	0.22464511573624324	[269,122]	[125,84]	2	hSpCas9	negative selection	266797
44237188	44237211	21	-	26472758	KBM7	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	0.22464511573624324	[269,122]	[125,84]	2	hSpCas9	negative selection	266798
5032144	5032167	21	+	26472758	KBM7	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	-0.04043564575319902	[306,291]	[75,191]	0	hSpCas9	negative selection	266799
44231331	44231354	21	-	26472758	KBM7	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	-0.04043564575319902	[306,291]	[75,191]	0	hSpCas9	negative selection	266800
44236960	44236983	21	+	26472758	KBM7	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.7275720168018558	[192,360]	[196,246]	7	hSpCas9	negative selection	266801
5026515	5026538	21	-	26472758	KBM7	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.7275720168018558	[192,360]	[196,246]	7	hSpCas9	negative selection	266802
44235321	44235344	21	+	26472758	KBM7	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.796652538852956	[478,368]	[420,273]	8	hSpCas9	negative selection	266803
5028154	5028177	21	-	26472758	KBM7	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.796652538852956	[478,368]	[420,273]	8	hSpCas9	negative selection	266804
5026389	5026412	21	+	26472758	KBM7	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.40941888300687157	[662,380]	[392,251]	4	hSpCas9	negative selection	266805
44237086	44237109	21	-	26472758	KBM7	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.40941888300687157	[662,380]	[392,251]	4	hSpCas9	negative selection	266806
44235502	44235525	21	+	26472758	KBM7	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	-0.32199273683960605	[195,113]	[37,73]	-3	hSpCas9	negative selection	266807
5027973	5027996	21	-	26472758	KBM7	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	-0.32199273683960605	[195,113]	[37,73]	-3	hSpCas9	negative selection	266808
44235428	44235451	21	-	26472758	KBM7	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.2718039118318584	[536,478]	[342,238]	3	hSpCas9	negative selection	266809
5028047	5028070	21	+	26472758	KBM7	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.2718039118318584	[536,478]	[342,238]	3	hSpCas9	negative selection	266810
5028104	5028127	21	+	26472758	KBM7	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.09624357749304302	[835,659]	[405,343]	0	hSpCas9	negative selection	266811
44235371	44235394	21	-	26472758	KBM7	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.09624357749304302	[835,659]	[405,343]	0	hSpCas9	negative selection	266812
44236985	44237008	21	+	26472758	KBM7	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	-0.29269871637391653	[271,308]	[116,108]	-3	hSpCas9	negative selection	266813
5026490	5026513	21	-	26472758	KBM7	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	-0.29269871637391653	[271,308]	[116,108]	-3	hSpCas9	negative selection	266814
5026575	5026598	21	+	26472758	KBM7	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.5212552840720033	[371,285]	[179,255]	5	hSpCas9	negative selection	266815
44236900	44236923	21	-	26472758	KBM7	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.5212552840720033	[371,285]	[179,255]	5	hSpCas9	negative selection	266816
5026287	5026310	21	+	26472758	Raji	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	1.3483916348773943	[43]	[25]	9	hSpCas9	negative selection	457915
44237188	44237211	21	-	26472758	Raji	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	1.3483916348773943	[43]	[25]	9	hSpCas9	negative selection	457916
5032144	5032167	21	+	26472758	Raji	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.37747269874134387	[135]	[40]	3	hSpCas9	negative selection	457917
44231331	44231354	21	-	26472758	Raji	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.37747269874134387	[135]	[40]	3	hSpCas9	negative selection	457918
44236960	44236983	21	+	26472758	Raji	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	1.7262933680180934	[55]	[42]	9	hSpCas9	negative selection	457919
5026515	5026538	21	-	26472758	Raji	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	1.7262933680180934	[55]	[42]	9	hSpCas9	negative selection	457920
44235321	44235344	21	+	26472758	Raji	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	-0.31810075134036	[230]	[42]	-3	hSpCas9	negative selection	457921
5028154	5028177	21	-	26472758	Raji	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	-0.31810075134036	[230]	[42]	-3	hSpCas9	negative selection	457922
5026389	5026412	21	+	26472758	Raji	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.7994850003902951	[306]	[123]	7	hSpCas9	negative selection	457923
44237086	44237109	21	-	26472758	Raji	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.7994850003902951	[306]	[123]	7	hSpCas9	negative selection	457924
44235502	44235525	21	+	26472758	Raji	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	0.48289267046580564	[36]	[11]	4	hSpCas9	negative selection	457925
5027973	5027996	21	-	26472758	Raji	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	0.48289267046580564	[36]	[11]	4	hSpCas9	negative selection	457926
44235428	44235451	21	-	26472758	Raji	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.21686201217209244	[240]	[64]	2	hSpCas9	negative selection	457927
5028047	5028070	21	+	26472758	Raji	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.21686201217209244	[240]	[64]	2	hSpCas9	negative selection	457928
5028104	5028127	21	+	26472758	Raji	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.744451057383598	[526]	[72]	-5	hSpCas9	negative selection	457929
44235371	44235394	21	-	26472758	Raji	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.744451057383598	[526]	[72]	-5	hSpCas9	negative selection	457930
44236985	44237008	21	+	26472758	Raji	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	0.43495819340210384	[101]	[31]	4	hSpCas9	negative selection	457931
5026490	5026513	21	-	26472758	Raji	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	0.43495819340210384	[101]	[31]	4	hSpCas9	negative selection	457932
5026575	5026598	21	+	26472758	Raji	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.8062140006530344	[137]	[55]	7	hSpCas9	negative selection	457933
44236900	44236923	21	-	26472758	Raji	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.8062140006530344	[137]	[55]	7	hSpCas9	negative selection	457934
5026287	5026310	21	+	26472758	K562	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-1.1627566538394265	[121]	[45]	-6	hSpCas9	negative selection	649033
44237188	44237211	21	-	26472758	K562	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-1.1627566538394265	[121]	[45]	-6	hSpCas9	negative selection	649034
5032144	5032167	21	+	26472758	K562	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.740376222328858	[155]	[219]	6	hSpCas9	negative selection	649035
44231331	44231354	21	-	26472758	K562	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.740376222328858	[155]	[219]	6	hSpCas9	negative selection	649036
44236960	44236983	21	+	26472758	K562	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.823229001406008	[234]	[350]	6	hSpCas9	negative selection	649037
5026515	5026538	21	-	26472758	K562	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.823229001406008	[234]	[350]	6	hSpCas9	negative selection	649038
44235321	44235344	21	+	26472758	K562	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.5918024032364789	[381]	[485]	5	hSpCas9	negative selection	649039
5028154	5028177	21	-	26472758	K562	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.5918024032364789	[381]	[485]	5	hSpCas9	negative selection	649040
5026389	5026412	21	+	26472758	K562	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.33733462457445285	[465]	[496]	2	hSpCas9	negative selection	649041
44237086	44237109	21	-	26472758	K562	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.33733462457445285	[465]	[496]	2	hSpCas9	negative selection	649042
44235502	44235525	21	+	26472758	K562	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	-7.22318682241655	[176]	[0]	-9	hSpCas9	negative selection	649043
5027973	5027996	21	-	26472758	K562	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	-7.22318682241655	[176]	[0]	-9	hSpCas9	negative selection	649044
44235428	44235451	21	-	26472758	K562	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.7669587278537879	[306]	[440]	6	hSpCas9	negative selection	649045
5028047	5028070	21	+	26472758	K562	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.7669587278537879	[306]	[440]	6	hSpCas9	negative selection	649046
5028104	5028127	21	+	26472758	K562	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-1.1769105174801209	[765]	[285]	-6	hSpCas9	negative selection	649047
44235371	44235394	21	-	26472758	K562	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-1.1769105174801209	[765]	[285]	-6	hSpCas9	negative selection	649048
44236985	44237008	21	+	26472758	K562	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	0.15695588641610736	[186]	[175]	1	hSpCas9	negative selection	649049
5026490	5026513	21	-	26472758	K562	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	0.15695588641610736	[186]	[175]	1	hSpCas9	negative selection	649050
5026575	5026598	21	+	26472758	K562	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.5867530332156463	[350]	[444]	5	hSpCas9	negative selection	649051
44236900	44236923	21	-	26472758	K562	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.5867530332156463	[350]	[444]	5	hSpCas9	negative selection	649052
44229021	44229044	21	+	26627737	DLD1	viability	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	-0.09419473676429879	[1684]	[578,378,513]	-1	hSpCas9	negative selection	816437
5034583	5034606	21	-	26627737	DLD1	viability	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	-0.09419473676429879	[1684]	[578,378,513]	-1	hSpCas9	negative selection	816438
44229834	44229857	21	+	26627737	DLD1	viability	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.3521094309371413	[243]	[101,104,86]	3	hSpCas9	negative selection	816439
5033641	5033664	21	-	26627737	DLD1	viability	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.3521094309371413	[243]	[101,104,86]	3	hSpCas9	negative selection	816440
44231317	44231340	21	-	26627737	DLD1	viability	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	0.5287146561926988	[41]	[13,17,23]	5	hSpCas9	negative selection	816441
5032158	5032181	21	+	26627737	DLD1	viability	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	0.5287146561926988	[41]	[13,17,23]	5	hSpCas9	negative selection	816442
44235453	44235476	21	+	26627737	DLD1	viability	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.12459463023200867	[287]	[69,58,112]	-1	hSpCas9	negative selection	816443
5028022	5028045	21	-	26627737	DLD1	viability	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.12459463023200867	[287]	[69,58,112]	-1	hSpCas9	negative selection	816444
44236960	44236983	21	+	26627737	DLD1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.653649771158546	[314]	[66,106,21]	-6	hSpCas9	negative selection	816445
5026515	5026538	21	-	26627737	DLD1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.653649771158546	[314]	[66,106,21]	-6	hSpCas9	negative selection	816446
44237004	44237027	21	-	26627737	DLD1	viability	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.2159582717660558	[573]	[146,312,174]	2	hSpCas9	negative selection	816447
5026471	5026494	21	+	26627737	DLD1	viability	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.2159582717660558	[573]	[146,312,174]	2	hSpCas9	negative selection	816448
44229021	44229044	21	+	26627737	GBM cells	viability after 5 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.1421034693226082	[609]	[335,385]	2	hSpCas9	negative selection	898752
5034583	5034606	21	-	26627737	GBM cells	viability after 5 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.1421034693226082	[609]	[335,385]	2	hSpCas9	negative selection	898753
44229834	44229857	21	+	26627737	GBM cells	viability after 5 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-0.22661700719817368	[71]	[24,40]	-4	hSpCas9	negative selection	898754
5033641	5033664	21	-	26627737	GBM cells	viability after 5 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-0.22661700719817368	[71]	[24,40]	-4	hSpCas9	negative selection	898755
44231317	44231340	21	-	26627737	GBM cells	viability after 5 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.36412053094810837	[5]	[2,1]	-5	hSpCas9	negative selection	898756
5032158	5032181	21	+	26627737	GBM cells	viability after 5 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.36412053094810837	[5]	[2,1]	-5	hSpCas9	negative selection	898757
44235453	44235476	21	+	26627737	GBM cells	viability after 5 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.1226192866639556	[134]	[60,71]	-2	hSpCas9	negative selection	898758
5028022	5028045	21	-	26627737	GBM cells	viability after 5 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.1226192866639556	[134]	[60,71]	-2	hSpCas9	negative selection	898759
44236960	44236983	21	+	26627737	GBM cells	viability after 5 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.7494329762104637	[126]	[119,108]	8	hSpCas9	negative selection	898760
5026515	5026538	21	-	26627737	GBM cells	viability after 5 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.7494329762104637	[126]	[119,108]	8	hSpCas9	negative selection	898761
44237004	44237027	21	-	26627737	GBM cells	viability after 5 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	-0.10508805567181073	[360]	[195,163]	-2	hSpCas9	negative selection	898762
5026471	5026494	21	+	26627737	GBM cells	viability after 5 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	-0.10508805567181073	[360]	[195,163]	-2	hSpCas9	negative selection	898763
44229021	44229044	21	+	26627737	GBM cells	viability after 13 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.1365618865819822	[609]	[370,357]	1	hSpCas9	negative selection	981067
5034583	5034606	21	-	26627737	GBM cells	viability after 13 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.1365618865819822	[609]	[370,357]	1	hSpCas9	negative selection	981068
44229834	44229857	21	+	26627737	GBM cells	viability after 13 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-0.45084332677500694	[71]	[16,37]	-5	hSpCas9	negative selection	981069
5033641	5033664	21	-	26627737	GBM cells	viability after 13 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-0.45084332677500694	[71]	[16,37]	-5	hSpCas9	negative selection	981070
44231317	44231340	21	-	26627737	GBM cells	viability after 13 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.3515303658147877	[5]	[1,2]	-4	hSpCas9	negative selection	981071
5032158	5032181	21	+	26627737	GBM cells	viability after 13 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.3515303658147877	[5]	[1,2]	-4	hSpCas9	negative selection	981072
44235453	44235476	21	+	26627737	GBM cells	viability after 13 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	0.26748904341888036	[134]	[80,93]	3	hSpCas9	negative selection	981073
5028022	5028045	21	-	26627737	GBM cells	viability after 13 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	0.26748904341888036	[134]	[80,93]	3	hSpCas9	negative selection	981074
44236960	44236983	21	+	26627737	GBM cells	viability after 13 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.925383106623217	[126]	[142,120]	9	hSpCas9	negative selection	981075
5026515	5026538	21	-	26627737	GBM cells	viability after 13 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.925383106623217	[126]	[142,120]	9	hSpCas9	negative selection	981076
44237004	44237027	21	-	26627737	GBM cells	viability after 13 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	-0.29840251718162336	[360]	[150,165]	-4	hSpCas9	negative selection	981077
5026471	5026494	21	+	26627737	GBM cells	viability after 13 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	-0.29840251718162336	[360]	[150,165]	-4	hSpCas9	negative selection	981078
44229021	44229044	21	+	26627737	GBM cells	viability after 21 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	-0.016738452311750862	[609]	[360,296]	0	hSpCas9	negative selection	1063382
5034583	5034606	21	-	26627737	GBM cells	viability after 21 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	-0.016738452311750862	[609]	[360,296]	0	hSpCas9	negative selection	1063383
44229834	44229857	21	+	26627737	GBM cells	viability after 21 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-1.0026463221479527	[71]	[18,19]	-7	hSpCas9	negative selection	1063384
5033641	5033664	21	-	26627737	GBM cells	viability after 21 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-1.0026463221479527	[71]	[18,19]	-7	hSpCas9	negative selection	1063385
44231317	44231340	21	-	26627737	GBM cells	viability after 21 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.704729201105498	[5]	[1,1]	-6	hSpCas9	negative selection	1063386
5032158	5032181	21	+	26627737	GBM cells	viability after 21 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.704729201105498	[5]	[1,1]	-6	hSpCas9	negative selection	1063387
44235453	44235476	21	+	26627737	GBM cells	viability after 21 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.7018822440081881	[134]	[42,46]	-6	hSpCas9	negative selection	1063388
5028022	5028045	21	-	26627737	GBM cells	viability after 21 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.7018822440081881	[134]	[42,46]	-6	hSpCas9	negative selection	1063389
44236960	44236983	21	+	26627737	GBM cells	viability after 21 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	1.2141778474180833	[126]	[169,150]	9	hSpCas9	negative selection	1063390
5026515	5026538	21	-	26627737	GBM cells	viability after 21 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	1.2141778474180833	[126]	[169,150]	9	hSpCas9	negative selection	1063391
44237004	44237027	21	-	26627737	GBM cells	viability after 21 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	-0.9775478900907939	[360]	[108,90]	-7	hSpCas9	negative selection	1063392
5026471	5026494	21	+	26627737	GBM cells	viability after 21 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	-0.9775478900907939	[360]	[108,90]	-7	hSpCas9	negative selection	1063393
44229021	44229044	21	+	26627737	RPE1	viability after 9 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.023719527124682616	[2157]	[650,732]	0	hSpCas9	negative selection	1145697
5034583	5034606	21	-	26627737	RPE1	viability after 9 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.023719527124682616	[2157]	[650,732]	0	hSpCas9	negative selection	1145698
44229834	44229857	21	+	26627737	RPE1	viability after 9 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-0.94098871898424	[871]	[146,135]	-6	hSpCas9	negative selection	1145699
5033641	5033664	21	-	26627737	RPE1	viability after 9 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-0.94098871898424	[871]	[146,135]	-6	hSpCas9	negative selection	1145700
44231317	44231340	21	-	26627737	RPE1	viability after 9 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.8489238200227978	[87]	[6,25]	-6	hSpCas9	negative selection	1145701
5032158	5032181	21	+	26627737	RPE1	viability after 9 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.8489238200227978	[87]	[6,25]	-6	hSpCas9	negative selection	1145702
44235453	44235476	21	+	26627737	RPE1	viability after 9 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.9385639191867474	[235]	[0,86]	-6	hSpCas9	negative selection	1145703
5028022	5028045	21	-	26627737	RPE1	viability after 9 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.9385639191867474	[235]	[0,86]	-6	hSpCas9	negative selection	1145704
44236960	44236983	21	+	26627737	RPE1	viability after 9 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-1.0104965015566088	[598]	[103,78]	-6	hSpCas9	negative selection	1145705
5026515	5026538	21	-	26627737	RPE1	viability after 9 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-1.0104965015566088	[598]	[103,78]	-6	hSpCas9	negative selection	1145706
44237004	44237027	21	-	26627737	RPE1	viability after 9 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	1.1705815030721785	[730]	[529,495]	7	hSpCas9	negative selection	1145707
5026471	5026494	21	+	26627737	RPE1	viability after 9 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	1.1705815030721785	[730]	[529,495]	7	hSpCas9	negative selection	1145708
44229021	44229044	21	+	26627737	RPE1	viability after 12 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.4945217823496524	[2157]	[861,768]	3	hSpCas9	negative selection	1228012
5034583	5034606	21	-	26627737	RPE1	viability after 12 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.4945217823496524	[2157]	[861,768]	3	hSpCas9	negative selection	1228013
44229834	44229857	21	+	26627737	RPE1	viability after 12 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-1.426289465470099	[871]	[160,8]	-7	hSpCas9	negative selection	1228014
5033641	5033664	21	-	26627737	RPE1	viability after 12 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-1.426289465470099	[871]	[160,8]	-7	hSpCas9	negative selection	1228015
44231317	44231340	21	-	26627737	RPE1	viability after 12 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.6702354108806712	[87]	[9,19]	-4	hSpCas9	negative selection	1228016
5032158	5032181	21	+	26627737	RPE1	viability after 12 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.6702354108806712	[87]	[9,19]	-4	hSpCas9	negative selection	1228017
44235453	44235476	21	+	26627737	RPE1	viability after 12 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-5.415374936492578	[235]	[0,1]	-9	hSpCas9	negative selection	1228018
5028022	5028045	21	-	26627737	RPE1	viability after 12 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-5.415374936492578	[235]	[0,1]	-9	hSpCas9	negative selection	1228019
44236960	44236983	21	+	26627737	RPE1	viability after 12 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.07277212722823334	[598]	[228,105]	0	hSpCas9	negative selection	1228020
5026515	5026538	21	-	26627737	RPE1	viability after 12 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.07277212722823334	[598]	[228,105]	0	hSpCas9	negative selection	1228021
44237004	44237027	21	-	26627737	RPE1	viability after 12 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.7743331570990997	[730]	[349,320]	5	hSpCas9	negative selection	1228022
5026471	5026494	21	+	26627737	RPE1	viability after 12 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.7743331570990997	[730]	[349,320]	5	hSpCas9	negative selection	1228023
44229021	44229044	21	+	26627737	RPE1	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.18096398551372816	[2157]	[858,530]	1	hSpCas9	negative selection	1310327
5034583	5034606	21	-	26627737	RPE1	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.18096398551372816	[2157]	[858,530]	1	hSpCas9	negative selection	1310328
44229834	44229857	21	+	26627737	RPE1	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-0.6064847103051526	[871]	[301,26]	-4	hSpCas9	negative selection	1310329
5033641	5033664	21	-	26627737	RPE1	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-0.6064847103051526	[871]	[301,26]	-4	hSpCas9	negative selection	1310330
44231317	44231340	21	-	26627737	RPE1	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.2528452871074678	[87]	[26,14]	-1	hSpCas9	negative selection	1310331
5032158	5032181	21	+	26627737	RPE1	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.2528452871074678	[87]	[26,14]	-1	hSpCas9	negative selection	1310332
44235453	44235476	21	+	26627737	RPE1	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-3.2313292695871825	[235]	[0,12]	-9	hSpCas9	negative selection	1310333
5028022	5028045	21	-	26627737	RPE1	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-3.2313292695871825	[235]	[0,12]	-9	hSpCas9	negative selection	1310334
44236960	44236983	21	+	26627737	RPE1	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.6039390718021065	[598]	[55,164]	-4	hSpCas9	negative selection	1310335
5026515	5026538	21	-	26627737	RPE1	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.6039390718021065	[598]	[55,164]	-4	hSpCas9	negative selection	1310336
44237004	44237027	21	-	26627737	RPE1	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.9031310587795979	[730]	[402,370]	5	hSpCas9	negative selection	1310337
5026471	5026494	21	+	26627737	RPE1	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.9031310587795979	[730]	[402,370]	5	hSpCas9	negative selection	1310338
44229021	44229044	21	+	26627737	RPE1	viability after 18 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.6139771186055851	[2157]	[1118,647]	4	hSpCas9	negative selection	1392642
5034583	5034606	21	-	26627737	RPE1	viability after 18 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.6139771186055851	[2157]	[1118,647]	4	hSpCas9	negative selection	1392643
44229834	44229857	21	+	26627737	RPE1	viability after 18 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-1.7542232149422339	[871]	[120,14]	-8	hSpCas9	negative selection	1392644
5033641	5033664	21	-	26627737	RPE1	viability after 18 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-1.7542232149422339	[871]	[120,14]	-8	hSpCas9	negative selection	1392645
44231317	44231340	21	-	26627737	RPE1	viability after 18 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-1.027593346871078	[87]	[15,6]	-6	hSpCas9	negative selection	1392646
5032158	5032181	21	+	26627737	RPE1	viability after 18 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-1.027593346871078	[87]	[15,6]	-6	hSpCas9	negative selection	1392647
44235453	44235476	21	+	26627737	RPE1	viability after 18 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-5.9929747892610985	[235]	[0,0]	-9	hSpCas9	negative selection	1392648
5028022	5028045	21	-	26627737	RPE1	viability after 18 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-5.9929747892610985	[235]	[0,0]	-9	hSpCas9	negative selection	1392649
44236960	44236983	21	+	26627737	RPE1	viability after 18 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.06543580604673033	[598]	[153,154]	0	hSpCas9	negative selection	1392650
5026515	5026538	21	-	26627737	RPE1	viability after 18 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.06543580604673033	[598]	[153,154]	0	hSpCas9	negative selection	1392651
44237004	44237027	21	-	26627737	RPE1	viability after 18 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.7758690218847746	[730]	[272,406]	5	hSpCas9	negative selection	1392652
5026471	5026494	21	+	26627737	RPE1	viability after 18 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.7758690218847746	[730]	[272,406]	5	hSpCas9	negative selection	1392653
44229021	44229044	21	+	26627737	HeLa	viability after 8 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	-1.0605380575349432	[1952]	[348,445,413]	-8	hSpCas9	negative selection	1474957
5034583	5034606	21	-	26627737	HeLa	viability after 8 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	-1.0605380575349432	[1952]	[348,445,413]	-8	hSpCas9	negative selection	1474958
44229834	44229857	21	+	26627737	HeLa	viability after 8 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-0.47913613541464906	[181]	[90,0,83]	-5	hSpCas9	negative selection	1474959
5033641	5033664	21	-	26627737	HeLa	viability after 8 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-0.47913613541464906	[181]	[90,0,83]	-5	hSpCas9	negative selection	1474960
44231317	44231340	21	-	26627737	HeLa	viability after 8 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	0.7395152381372633	[246]	[245,186,123]	6	hSpCas9	negative selection	1474961
5032158	5032181	21	+	26627737	HeLa	viability after 8 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	0.7395152381372633	[246]	[245,186,123]	6	hSpCas9	negative selection	1474962
44235453	44235476	21	+	26627737	HeLa	viability after 8 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	0.4563826710495385	[246]	[129,211,99]	4	hSpCas9	negative selection	1474963
5028022	5028045	21	-	26627737	HeLa	viability after 8 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	0.4563826710495385	[246]	[129,211,99]	4	hSpCas9	negative selection	1474964
44236960	44236983	21	+	26627737	HeLa	viability after 8 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-1.772459364201948	[387]	[69,80,4]	-9	hSpCas9	negative selection	1474965
5026515	5026538	21	-	26627737	HeLa	viability after 8 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-1.772459364201948	[387]	[69,80,4]	-9	hSpCas9	negative selection	1474966
44237004	44237027	21	-	26627737	HeLa	viability after 8 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	-0.22262500356008696	[863]	[342,347,282]	-2	hSpCas9	negative selection	1474967
5026471	5026494	21	+	26627737	HeLa	viability after 8 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	-0.22262500356008696	[863]	[342,347,282]	-2	hSpCas9	negative selection	1474968
44229021	44229044	21	+	26627737	HeLa	viability after 12 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	-1.2094533066009459	[1952]	[345,310,393]	-8	hSpCas9	negative selection	1557272
5034583	5034606	21	-	26627737	HeLa	viability after 12 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	-1.2094533066009459	[1952]	[345,310,393]	-8	hSpCas9	negative selection	1557273
44229834	44229857	21	+	26627737	HeLa	viability after 12 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-1.0931287238022027	[181]	[21,19,64]	-7	hSpCas9	negative selection	1557274
5033641	5033664	21	-	26627737	HeLa	viability after 12 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-1.0931287238022027	[181]	[21,19,64]	-7	hSpCas9	negative selection	1557275
44231317	44231340	21	-	26627737	HeLa	viability after 12 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	1.027653346690463	[246]	[324,110,201]	7	hSpCas9	negative selection	1557276
5032158	5032181	21	+	26627737	HeLa	viability after 12 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	1.027653346690463	[246]	[324,110,201]	7	hSpCas9	negative selection	1557277
44235453	44235476	21	+	26627737	HeLa	viability after 12 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	0.5081147786515567	[246]	[41,83,312]	4	hSpCas9	negative selection	1557278
5028022	5028045	21	-	26627737	HeLa	viability after 12 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	0.5081147786515567	[246]	[41,83,312]	4	hSpCas9	negative selection	1557279
44236960	44236983	21	+	26627737	HeLa	viability after 12 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.06770309738550992	[387]	[77,103,279]	0	hSpCas9	negative selection	1557280
5026515	5026538	21	-	26627737	HeLa	viability after 12 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.06770309738550992	[387]	[77,103,279]	0	hSpCas9	negative selection	1557281
44237004	44237027	21	-	26627737	HeLa	viability after 12 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.3344256495187823	[863]	[437,499,406]	3	hSpCas9	negative selection	1557282
5026471	5026494	21	+	26627737	HeLa	viability after 12 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.3344256495187823	[863]	[437,499,406]	3	hSpCas9	negative selection	1557283
44229021	44229044	21	+	26627737	HeLa	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	-0.7089559698465941	[1952]	[669,261,527]	-6	hSpCas9	negative selection	1639587
5034583	5034606	21	-	26627737	HeLa	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	-0.7089559698465941	[1952]	[669,261,527]	-6	hSpCas9	negative selection	1639588
44229834	44229857	21	+	26627737	HeLa	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.030407416418098077	[181]	[110,106,2]	0	hSpCas9	negative selection	1639589
5033641	5033664	21	-	26627737	HeLa	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.030407416418098077	[181]	[110,106,2]	0	hSpCas9	negative selection	1639590
44231317	44231340	21	-	26627737	HeLa	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	1.3795649253633324	[246]	[285,243,253]	8	hSpCas9	negative selection	1639591
5032158	5032181	21	+	26627737	HeLa	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	1.3795649253633324	[246]	[285,243,253]	8	hSpCas9	negative selection	1639592
44235453	44235476	21	+	26627737	HeLa	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	0.629955797590775	[246]	[177,223,56]	5	hSpCas9	negative selection	1639593
5028022	5028045	21	-	26627737	HeLa	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	0.629955797590775	[246]	[177,223,56]	5	hSpCas9	negative selection	1639594
44236960	44236983	21	+	26627737	HeLa	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.12525141864109546	[387]	[251,0,182]	-1	hSpCas9	negative selection	1639595
5026515	5026538	21	-	26627737	HeLa	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.12525141864109546	[387]	[251,0,182]	-1	hSpCas9	negative selection	1639596
44237004	44237027	21	-	26627737	HeLa	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.5513574850018157	[863]	[425,539,586]	4	hSpCas9	negative selection	1639597
5026471	5026494	21	+	26627737	HeLa	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.5513574850018157	[863]	[425,539,586]	4	hSpCas9	negative selection	1639598
44229021	44229044	21	+	26627737	HeLa	viability after 18 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	-0.7247520776364016	[1952]	[443,210,527]	-6	hSpCas9	negative selection	1721902
5034583	5034606	21	-	26627737	HeLa	viability after 18 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	-0.7247520776364016	[1952]	[443,210,527]	-6	hSpCas9	negative selection	1721903
44229834	44229857	21	+	26627737	HeLa	viability after 18 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.03474880762292121	[181]	[72,90,2]	0	hSpCas9	negative selection	1721904
5033641	5033664	21	-	26627737	HeLa	viability after 18 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.03474880762292121	[181]	[72,90,2]	0	hSpCas9	negative selection	1721905
44231317	44231340	21	-	26627737	HeLa	viability after 18 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	1.383733633422911	[246]	[194,199,253]	8	hSpCas9	negative selection	1721906
5032158	5032181	21	+	26627737	HeLa	viability after 18 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	1.383733633422911	[246]	[194,199,253]	8	hSpCas9	negative selection	1721907
44235453	44235476	21	+	26627737	HeLa	viability after 18 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	0.6336952589117846	[246]	[122,181,56]	5	hSpCas9	negative selection	1721908
5028022	5028045	21	-	26627737	HeLa	viability after 18 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	0.6336952589117846	[246]	[122,181,56]	5	hSpCas9	negative selection	1721909
44236960	44236983	21	+	26627737	HeLa	viability after 18 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.1665325868381113	[387]	[160,0,182]	-1	hSpCas9	negative selection	1721910
5026515	5026538	21	-	26627737	HeLa	viability after 18 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.1665325868381113	[387]	[160,0,182]	-1	hSpCas9	negative selection	1721911
44237004	44237027	21	-	26627737	HeLa	viability after 18 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.5708810652596294	[863]	[285,463,586]	4	hSpCas9	negative selection	1721912
5026471	5026494	21	+	26627737	HeLa	viability after 18 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.5708810652596294	[863]	[285,463,586]	4	hSpCas9	negative selection	1721913
44229021	44229044	21	+	26627737	HCT116	viability after 6 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.5392962350232708	[2890]	[1072,432]	3	hSpCas9	negative selection	1804217
5034583	5034606	21	-	26627737	HCT116	viability after 6 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.5392962350232708	[2890]	[1072,432]	3	hSpCas9	negative selection	1804218
44229834	44229857	21	+	26627737	HCT116	viability after 6 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.17877904410737377	[202]	[97,1]	1	hSpCas9	negative selection	1804219
5033641	5033664	21	-	26627737	HCT116	viability after 6 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.17877904410737377	[202]	[97,1]	1	hSpCas9	negative selection	1804220
44231317	44231340	21	-	26627737	HCT116	viability after 6 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-1.7246389381267964	[518]	[34,18]	-7	hSpCas9	negative selection	1804221
5032158	5032181	21	+	26627737	HCT116	viability after 6 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-1.7246389381267964	[518]	[34,18]	-7	hSpCas9	negative selection	1804222
44235453	44235476	21	+	26627737	HCT116	viability after 6 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-2.5469355290936724	[246]	[5,6]	-8	hSpCas9	negative selection	1804223
5028022	5028045	21	-	26627737	HCT116	viability after 6 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-2.5469355290936724	[246]	[5,6]	-8	hSpCas9	negative selection	1804224
44236960	44236983	21	+	26627737	HCT116	viability after 6 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-1.2214097432858977	[349]	[40,13]	-6	hSpCas9	negative selection	1804225
5026515	5026538	21	-	26627737	HCT116	viability after 6 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-1.2214097432858977	[349]	[40,13]	-6	hSpCas9	negative selection	1804226
44237004	44237027	21	-	26627737	HCT116	viability after 6 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	2.630891740129316	[704]	[224,940]	9	hSpCas9	negative selection	1804227
5026471	5026494	21	+	26627737	HCT116	viability after 6 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	2.630891740129316	[704]	[224,940]	9	hSpCas9	negative selection	1804228
44229021	44229044	21	+	26627737	HCT116	viability after 8 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.8921984800603697	[604]	[648,526,679]	7	hSpCas9	negative selection	1886532
5034583	5034606	21	-	26627737	HCT116	viability after 8 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.8921984800603697	[604]	[648,526,679]	7	hSpCas9	negative selection	1886533
44229834	44229857	21	+	26627737	HCT116	viability after 8 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	1.1621873642863298	[38]	[34,56,51]	8	hSpCas9	negative selection	1886534
5033641	5033664	21	-	26627737	HCT116	viability after 8 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	1.1621873642863298	[38]	[34,56,51]	8	hSpCas9	negative selection	1886535
44231317	44231340	21	-	26627737	HCT116	viability after 8 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.7641319732981047	[418]	[97,77,229]	-7	hSpCas9	negative selection	1886536
5032158	5032181	21	+	26627737	HCT116	viability after 8 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.7641319732981047	[418]	[97,77,229]	-7	hSpCas9	negative selection	1886537
44235453	44235476	21	+	26627737	HCT116	viability after 8 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.3612292055528482	[156]	[81,109,10]	-4	hSpCas9	negative selection	1886538
5028022	5028045	21	-	26627737	HCT116	viability after 8 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.3612292055528482	[156]	[81,109,10]	-4	hSpCas9	negative selection	1886539
44236960	44236983	21	+	26627737	HCT116	viability after 8 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.4317403736729213	[187]	[143,112,161]	4	hSpCas9	negative selection	1886540
5026515	5026538	21	-	26627737	HCT116	viability after 8 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.4317403736729213	[187]	[143,112,161]	4	hSpCas9	negative selection	1886541
44237004	44237027	21	-	26627737	HCT116	viability after 8 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	-0.00995815549478457	[405]	[196,239,228]	0	hSpCas9	negative selection	1886542
5026471	5026494	21	+	26627737	HCT116	viability after 8 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	-0.00995815549478457	[405]	[196,239,228]	0	hSpCas9	negative selection	1886543
44229021	44229044	21	+	26627737	HCT116	viability after 9 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	-0.07338215295317996	[2890]	[650,798]	0	hSpCas9	negative selection	1968847
5034583	5034606	21	-	26627737	HCT116	viability after 9 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	-0.07338215295317996	[2890]	[650,798]	0	hSpCas9	negative selection	1968848
44229834	44229857	21	+	26627737	HCT116	viability after 9 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.19154239551949148	[202]	[38,79]	1	hSpCas9	negative selection	1968849
5033641	5033664	21	-	26627737	HCT116	viability after 9 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.19154239551949148	[202]	[38,79]	1	hSpCas9	negative selection	1968850
44231317	44231340	21	-	26627737	HCT116	viability after 9 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-1.7047513272176753	[518]	[70,19]	-8	hSpCas9	negative selection	1968851
5032158	5032181	21	+	26627737	HCT116	viability after 9 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-1.7047513272176753	[518]	[70,19]	-8	hSpCas9	negative selection	1968852
44235453	44235476	21	+	26627737	HCT116	viability after 9 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	0.36540175079994885	[246]	[70,95]	2	hSpCas9	negative selection	1968853
5028022	5028045	21	-	26627737	HCT116	viability after 9 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	0.36540175079994885	[246]	[70,95]	2	hSpCas9	negative selection	1968854
44236960	44236983	21	+	26627737	HCT116	viability after 9 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.25516470764768306	[349]	[41,106]	-2	hSpCas9	negative selection	1968855
5026515	5026538	21	-	26627737	HCT116	viability after 9 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.25516470764768306	[349]	[41,106]	-2	hSpCas9	negative selection	1968856
44237004	44237027	21	-	26627737	HCT116	viability after 9 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	1.0564286584016902	[704]	[233,515]	7	hSpCas9	negative selection	1968857
5026471	5026494	21	+	26627737	HCT116	viability after 9 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	1.0564286584016902	[704]	[233,515]	7	hSpCas9	negative selection	1968858
44229021	44229044	21	+	26627737	HCT116	viability after 12 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	1.0154990964560255	[604]	[612,688,629]	8	hSpCas9	negative selection	2051162
5034583	5034606	21	-	26627737	HCT116	viability after 12 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	1.0154990964560255	[604]	[612,688,629]	8	hSpCas9	negative selection	2051163
44229834	44229857	21	+	26627737	HCT116	viability after 12 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	2.3858151469869293	[38]	[111,68,138]	9	hSpCas9	negative selection	2051164
5033641	5033664	21	-	26627737	HCT116	viability after 12 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	2.3858151469869293	[38]	[111,68,138]	9	hSpCas9	negative selection	2051165
44231317	44231340	21	-	26627737	HCT116	viability after 12 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.7348381253076814	[418]	[78,147,174]	-7	hSpCas9	negative selection	2051166
5032158	5032181	21	+	26627737	HCT116	viability after 12 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.7348381253076814	[418]	[78,147,174]	-7	hSpCas9	negative selection	2051167
44235453	44235476	21	+	26627737	HCT116	viability after 12 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-1.0089572688086634	[156]	[6,82,36]	-8	hSpCas9	negative selection	2051168
5028022	5028045	21	-	26627737	HCT116	viability after 12 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-1.0089572688086634	[156]	[6,82,36]	-8	hSpCas9	negative selection	2051169
44236960	44236983	21	+	26627737	HCT116	viability after 12 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.4334099151081498	[187]	[143,160,94]	4	hSpCas9	negative selection	2051170
5026515	5026538	21	-	26627737	HCT116	viability after 12 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.4334099151081498	[187]	[143,160,94]	4	hSpCas9	negative selection	2051171
44237004	44237027	21	-	26627737	HCT116	viability after 12 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	-0.10940718080535689	[405]	[338,158,81]	-1	hSpCas9	negative selection	2051172
5026471	5026494	21	+	26627737	HCT116	viability after 12 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	-0.10940718080535689	[405]	[338,158,81]	-1	hSpCas9	negative selection	2051173
44229021	44229044	21	+	26627737	HCT116	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.846335011429463	[604]	[756,660,473]	7	hSpCas9	negative selection	2133477
5034583	5034606	21	-	26627737	HCT116	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.846335011429463	[604]	[756,660,473]	7	hSpCas9	negative selection	2133478
44229834	44229857	21	+	26627737	HCT116	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	2.336962133455114	[38]	[162,106,75]	9	hSpCas9	negative selection	2133479
5033641	5033664	21	-	26627737	HCT116	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	2.336962133455114	[38]	[162,106,75]	9	hSpCas9	negative selection	2133480
44231317	44231340	21	-	26627737	HCT116	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.7459766842083999	[418]	[164,119,147]	-6	hSpCas9	negative selection	2133481
5032158	5032181	21	+	26627737	HCT116	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.7459766842083999	[418]	[164,119,147]	-6	hSpCas9	negative selection	2133482
44235453	44235476	21	+	26627737	HCT116	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.31185550196447276	[156]	[115,101,5]	-3	hSpCas9	negative selection	2133483
5028022	5028045	21	-	26627737	HCT116	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.31185550196447276	[156]	[115,101,5]	-3	hSpCas9	negative selection	2133484
44236960	44236983	21	+	26627737	HCT116	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.9347516739731501	[187]	[232,232,156]	7	hSpCas9	negative selection	2133485
5026515	5026538	21	-	26627737	HCT116	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.9347516739731501	[187]	[232,232,156]	7	hSpCas9	negative selection	2133486
44237004	44237027	21	-	26627737	HCT116	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.5619569315414729	[405]	[314,362,350]	5	hSpCas9	negative selection	2133487
5026471	5026494	21	+	26627737	HCT116	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.5619569315414729	[405]	[314,362,350]	5	hSpCas9	negative selection	2133488
44229021	44229044	21	+	26627737	HCT116	viability after 18 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	1.2037369392187962	[604]	[697,698,619]	8	hSpCas9	negative selection	2215792
5034583	5034606	21	-	26627737	HCT116	viability after 18 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	1.2037369392187962	[604]	[697,698,619]	8	hSpCas9	negative selection	2215793
44229834	44229857	21	+	26627737	HCT116	viability after 18 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	2.8362649814198395	[38]	[215,40,153]	9	hSpCas9	negative selection	2215794
5033641	5033664	21	-	26627737	HCT116	viability after 18 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	2.8362649814198395	[38]	[215,40,153]	9	hSpCas9	negative selection	2215795
44231317	44231340	21	-	26627737	HCT116	viability after 18 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.8123882318508551	[418]	[55,122,168]	-6	hSpCas9	negative selection	2215796
5032158	5032181	21	+	26627737	HCT116	viability after 18 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.8123882318508551	[418]	[55,122,168]	-6	hSpCas9	negative selection	2215797
44235453	44235476	21	+	26627737	HCT116	viability after 18 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.6910843695068497	[156]	[91,45,0]	-6	hSpCas9	negative selection	2215798
5028022	5028045	21	-	26627737	HCT116	viability after 18 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.6910843695068497	[156]	[91,45,0]	-6	hSpCas9	negative selection	2215799
44236960	44236983	21	+	26627737	HCT116	viability after 18 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	1.3286627907348527	[187]	[308,270,95]	8	hSpCas9	negative selection	2215800
5026515	5026538	21	-	26627737	HCT116	viability after 18 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	1.3286627907348527	[187]	[308,270,95]	8	hSpCas9	negative selection	2215801
44237004	44237027	21	-	26627737	HCT116	viability after 18 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.498472733896691	[405]	[190,362,271]	4	hSpCas9	negative selection	2215802
5026471	5026494	21	+	26627737	HCT116	viability after 18 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.498472733896691	[405]	[190,362,271]	4	hSpCas9	negative selection	2215803
44230908	44230931	21	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCAGGCTGGAGTGTAGTGG	ICOSLG	ENSG00000160223	1.1996159195397276	[69,17]	[36,4]	5	dCas9-VP64	positive selection	2463408
44230908	44230931	21	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCAGGCTGGAGTGTAGTGG	ICOSLG	ENSG00000160223	2.7040346189546693	[41,50]	[11,181]	9	dCas9-VP64	positive selection	2558663
44235385	44235408	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000160223	0.6192300531750153	[3,3]	[4,5]	9	hSpCas9	positive selection	2994678
5028091	5028114	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000277117	0.6192300531750153	[3,3]	[4,5]	9	hSpCas9	positive selection	2994679
44235443	44235466	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000160223	0.2837590070461275	[4,5]	[4,5]	6	hSpCas9	positive selection	2994680
5028033	5028056	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000277117	0.2837590070461275	[4,5]	[4,5]	6	hSpCas9	positive selection	2994681
44235385	44235408	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000160223	-0.6184359080779016	[3,3]	[2,0]	-7	hSpCas9	positive selection	2994682
5028091	5028114	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000277117	-0.6184359080779016	[3,3]	[2,0]	-7	hSpCas9	positive selection	2994683
5028128	5028151	21	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.03235531035654862	[4,3]	[4,2]	0	hSpCas9	positive selection	2994684
44235348	44235371	21	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.03235531035654862	[4,3]	[4,2]	0	hSpCas9	positive selection	2994685
44235385	44235408	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000160223	-0.2804461972138279	[3,3]	[3,0]	-4	hSpCas9	positive selection	3062536
5028091	5028114	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000277117	-0.2804461972138279	[3,3]	[3,0]	-4	hSpCas9	positive selection	3062537
44235443	44235466	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000160223	0.515927276856486	[4,4]	[4,4]	8	hSpCas9	positive selection	3062538
5028033	5028056	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000277117	0.515927276856486	[4,4]	[4,4]	8	hSpCas9	positive selection	3062539
44235385	44235408	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000160223	-0.42406954303256783	[3,3]	[1,1]	-6	hSpCas9	positive selection	3062540
5028091	5028114	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000277117	-0.42406954303256783	[3,3]	[1,1]	-6	hSpCas9	positive selection	3062541
5028128	5028151	21	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.37605271061929424	[4,4]	[3,3]	6	hSpCas9	positive selection	3062542
44235348	44235371	21	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.37605271061929424	[4,4]	[3,3]	6	hSpCas9	positive selection	3062543
5028147	5028170		+	24336571	A375	resistance to PLX after 7 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000277117	-0.3737285716770269	[6,4]	[4,3]	-9	hSpCas9	positive selection	3120262
44235328	44235351		-	24336571	A375	resistance to PLX after 7 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000160223	-0.3737285716770269	[6,4]	[4,3]	-9	hSpCas9	positive selection	3120263
5025024	5025047		-	24336571	A375	resistance to PLX after 7 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000277117	-0.7135033668930963	[3,3]	[1,1]	-9	hSpCas9	positive selection	3120264
44238451	44238474		+	24336571	A375	resistance to PLX after 7 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.7135033668930963	[3,3]	[1,1]	-9	hSpCas9	positive selection	3120265
44238447	44238470		-	24336571	A375	resistance to PLX after 7 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.6380884498347066	[6,4]	[2,3]	-9	hSpCas9	positive selection	3120266
5025028	5025051		+	24336571	A375	resistance to PLX after 7 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000277117	-0.6380884498347066	[6,4]	[2,3]	-9	hSpCas9	positive selection	3120267
5028047	5028070		+	24336571	A375	resistance to PLX after 7 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	-0.3288165182930006	[15,14]	[10,11]	-8	hSpCas9	positive selection	3120268
44235428	44235451		-	24336571	A375	resistance to PLX after 7 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	-0.3288165182930006	[15,14]	[10,11]	-8	hSpCas9	positive selection	3120269
5028147	5028170		+	24336571	A375	resistance to PLX after 14 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000277117	0.019214031159396794	[5,6]	[2,2]	0	hSpCas9	positive selection	3178055
44235328	44235351		-	24336571	A375	resistance to PLX after 14 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000160223	0.019214031159396794	[5,6]	[2,2]	0	hSpCas9	positive selection	3178056
5025024	5025047		-	24336571	A375	resistance to PLX after 14 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000277117	0.5319349911227053	[5,3]	[2,2]	5	hSpCas9	positive selection	3178057
44238451	44238474		+	24336571	A375	resistance to PLX after 14 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.5319349911227053	[5,3]	[2,2]	5	hSpCas9	positive selection	3178058
44238447	44238470		-	24336571	A375	resistance to PLX after 14 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	1.066464354381156	[6,4]	[5,5]	8	hSpCas9	positive selection	3178059
5025028	5025051		+	24336571	A375	resistance to PLX after 14 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000277117	1.066464354381156	[6,4]	[5,5]	8	hSpCas9	positive selection	3178060
5028047	5028070		+	24336571	A375	resistance to PLX after 14 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	-0.09056452372826901	[16,13]	[5,6]	-1	hSpCas9	positive selection	3178061
44235428	44235451		-	24336571	A375	resistance to PLX after 14 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	-0.09056452372826901	[16,13]	[5,6]	-1	hSpCas9	positive selection	3178062
5028147	5028170		+	24336571	A375	viability after 7 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000277117	-0.11907135514510814	[6]	[6,4]	-2	hSpCas9	negative selection	3235848
44235328	44235351		-	24336571	A375	viability after 7 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000160223	-0.11907135514510814	[6]	[6,4]	-2	hSpCas9	negative selection	3235849
5025024	5025047		-	24336571	A375	viability after 7 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000277117	1.0165166997303123	[1]	[3,3]	9	hSpCas9	negative selection	3235850
44238451	44238474		+	24336571	A375	viability after 7 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	1.0165166997303123	[1]	[3,3]	9	hSpCas9	negative selection	3235851
44238447	44238470		-	24336571	A375	viability after 7 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	1.5421697433177493	[1]	[6,4]	9	hSpCas9	negative selection	3235852
5025028	5025051		+	24336571	A375	viability after 7 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000277117	1.5421697433177493	[1]	[6,4]	9	hSpCas9	negative selection	3235853
5028047	5028070		+	24336571	A375	viability after 7 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.47601347808001326	[10]	[15,14]	7	hSpCas9	negative selection	3235854
44235428	44235451		-	24336571	A375	viability after 7 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.47601347808001326	[10]	[15,14]	7	hSpCas9	negative selection	3235855
5028147	5028170		+	24336571	A375	viability after 14 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000277117	0.04274794265967674	[6]	[5,6]	0	hSpCas9	negative selection	3293641
44235328	44235351		-	24336571	A375	viability after 14 days	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000160223	0.04274794265967674	[6]	[5,6]	0	hSpCas9	negative selection	3293642
5025024	5025047		-	24336571	A375	viability after 14 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000277117	1.2179300068222643	[1]	[5,3]	9	hSpCas9	negative selection	3293643
44238451	44238474		+	24336571	A375	viability after 14 days	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	1.2179300068222643	[1]	[5,3]	9	hSpCas9	negative selection	3293644
44238447	44238470		-	24336571	A375	viability after 14 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	1.6199724615972761	[1]	[6,4]	9	hSpCas9	negative selection	3293645
5025028	5025051		+	24336571	A375	viability after 14 days	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000277117	1.6199724615972761	[1]	[6,4]	9	hSpCas9	negative selection	3293646
5028047	5028070		+	24336571	A375	viability after 14 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.5479200575628775	[10]	[16,13]	7	hSpCas9	negative selection	3293647
44235428	44235451		-	24336571	A375	viability after 14 days	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.5479200575628775	[10]	[16,13]	7	hSpCas9	negative selection	3293648
44231279	44231302	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.7370272254130229	[254,254]	[0,0]	-5	hSpCas9	positive selection	3373655
5032196	5032219	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000277117	-0.7370272254130229	[254,254]	[0,0]	-5	hSpCas9	positive selection	3373656
44238447	44238470	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3373657
5025028	5025051	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000277117	1.2349583984173806	[64,64]	[0,0]	5	hSpCas9	positive selection	3373658
44238451	44238474	21	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	1.7654731151161607	[44,44]	[0,0]	7	hSpCas9	positive selection	3373659
5025024	5025047	21	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000277117	1.7654731151161607	[44,44]	[0,0]	7	hSpCas9	positive selection	3373660
5028090	5028113	21	+	26780180	HT29	viability (Avana library 4 designs)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000277117	1.45295390825747	[]	[]	5	hSpCas9	negative selection	3432018
44235385	44235408	21	-	26780180	HT29	viability (Avana library 4 designs)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000160223	1.45295390825747	[]	[]	5	hSpCas9	negative selection	3432019
5028032	5028055	21	+	26780180	HT29	viability (Avana library 4 designs)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000277117	0.364444633800667	[]	[]	1	hSpCas9	negative selection	3432020
44235443	44235466	21	-	26780180	HT29	viability (Avana library 4 designs)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000160223	0.364444633800667	[]	[]	1	hSpCas9	negative selection	3432021
44235384	44235407	21	+	26780180	HT29	viability (Avana library 4 designs)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000160223	0.490726259140632	[]	[]	1	hSpCas9	negative selection	3432022
5028091	5028114	21	-	26780180	HT29	viability (Avana library 4 designs)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000277117	0.490726259140632	[]	[]	1	hSpCas9	negative selection	3432023
44235348	44235371	21	-	26780180	HT29	viability (Avana library 4 designs)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.753635382708274	[]	[]	3	hSpCas9	negative selection	3432024
5028127	5028150	21	+	26780180	HT29	viability (Avana library 4 designs)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.753635382708274	[]	[]	3	hSpCas9	negative selection	3432025
44235348	44235371	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	5.09575632783386	[]	[]	8	hSpCas9	negative selection	3517961
5028127	5028150	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	5.09575632783386	[]	[]	8	hSpCas9	negative selection	3517962
5028032	5028055	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000277117	-7.29690038891831	[]	[]	-6	hSpCas9	negative selection	3517963
44235443	44235466	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000160223	-7.29690038891831	[]	[]	-6	hSpCas9	negative selection	3517964
5028090	5028113	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000277117	3.08647093542601	[]	[]	5	hSpCas9	negative selection	3517965
44235385	44235408	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000160223	3.08647093542601	[]	[]	5	hSpCas9	negative selection	3517966
44235384	44235407	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000160223	-0.512433229836318	[]	[]	0	hSpCas9	negative selection	3517967
5028091	5028114	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000277117	-0.512433229836318	[]	[]	0	hSpCas9	negative selection	3517968
5022678	5022701	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000277117	2.84202436201129	[]	[]	4	hSpCas9	negative selection	3517969
44240797	44240820	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000160223	2.84202436201129	[]	[]	4	hSpCas9	negative selection	3517970
44235498	44235521	21	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000160223	5.33445121870029	[]	[]	8	hSpCas9	negative selection	3517971
5027977	5028000	21	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000277117	5.33445121870029	[]	[]	8	hSpCas9	negative selection	3517972
44235348	44235371	21	-	26780180	A375	viability (Avana lentiGuide)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	-1.92283783207485	[]	[]	-3	hSpCas9	negative selection	3626620
5028127	5028150	21	+	26780180	A375	viability (Avana lentiGuide)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	-1.92283783207485	[]	[]	-3	hSpCas9	negative selection	3626621
5028032	5028055	21	+	26780180	A375	viability (Avana lentiGuide)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000277117	-5.29636037353129	[]	[]	-8	hSpCas9	negative selection	3626622
44235443	44235466	21	-	26780180	A375	viability (Avana lentiGuide)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000160223	-5.29636037353129	[]	[]	-8	hSpCas9	negative selection	3626623
5028090	5028113	21	+	26780180	A375	viability (Avana lentiGuide)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000277117	-0.298443290305413	[]	[]	0	hSpCas9	negative selection	3626624
44235385	44235408	21	-	26780180	A375	viability (Avana lentiGuide)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000160223	-0.298443290305413	[]	[]	0	hSpCas9	negative selection	3626625
44235384	44235407	21	+	26780180	A375	viability (Avana lentiGuide)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000160223	3.03672204426066	[]	[]	3	hSpCas9	negative selection	3626626
5028091	5028114	21	-	26780180	A375	viability (Avana lentiGuide)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000277117	3.03672204426066	[]	[]	3	hSpCas9	negative selection	3626627
5022678	5022701	21	-	26780180	A375	viability (Avana lentiGuide)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000277117	3.83817337926004	[]	[]	4	hSpCas9	negative selection	3626628
44240797	44240820	21	+	26780180	A375	viability (Avana lentiGuide)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000160223	3.83817337926004	[]	[]	4	hSpCas9	negative selection	3626629
44235498	44235521	21	+	26780180	A375	viability (Avana lentiGuide)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000160223	0.684465623650736	[]	[]	0	hSpCas9	negative selection	3626630
5027977	5028000	21	-	26780180	A375	viability (Avana lentiGuide)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000277117	0.684465623650736	[]	[]	0	hSpCas9	negative selection	3626631
44235348	44235371	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.24659068799402295	[5]	[6,5]	7	hSpCas9	positive selection	3735279
5028127	5028150	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.24659068799402295	[5]	[6,5]	7	hSpCas9	positive selection	3735280
5028032	5028055	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000277117	-0.39996467521596607	[7]	[5,4]	-5	hSpCas9	positive selection	3735281
44235443	44235466	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000160223	-0.39996467521596607	[7]	[5,4]	-5	hSpCas9	positive selection	3735282
5028090	5028113	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000277117	0.0678213989892422	[5]	[5,5]	1	hSpCas9	positive selection	3735283
44235385	44235408	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000160223	0.0678213989892422	[5]	[5,5]	1	hSpCas9	positive selection	3735284
44235384	44235407	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000160223	0.18804718070483822	[4]	[4,4]	5	hSpCas9	positive selection	3735285
5028091	5028114	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000277117	0.18804718070483822	[4]	[4,4]	5	hSpCas9	positive selection	3735286
5022678	5022701	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000277117	0.27432869588341224	[3]	[4,3]	7	hSpCas9	positive selection	3735287
44240797	44240820	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000160223	0.27432869588341224	[3]	[4,3]	7	hSpCas9	positive selection	3735288
44235498	44235521	21	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000160223	0.31111296656863885	[5]	[6,6]	8	hSpCas9	positive selection	3735289
5027977	5028000	21	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000277117	0.31111296656863885	[5]	[6,6]	8	hSpCas9	positive selection	3735290
44235348	44235371	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	-0.16154854852529182	[5]	[2,5]	-2	hSpCas9	positive selection	3843886
5028127	5028150	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	-0.16154854852529182	[5]	[2,5]	-2	hSpCas9	positive selection	3843887
5028032	5028055	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000277117	-0.10592179150047754	[6]	[4,5]	-1	hSpCas9	positive selection	3843888
44235443	44235466	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGTACTGGATCAATAAGACGG	ICOSLG	ENSG00000160223	-0.10592179150047754	[6]	[4,5]	-1	hSpCas9	positive selection	3843889
5028090	5028113	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000277117	0.17053859999790844	[5]	[5,4]	4	hSpCas9	positive selection	3843890
44235385	44235408	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCGTCTTCTTGAACATGCGGGG	ICOSLG	ENSG00000160223	0.17053859999790844	[5]	[5,4]	4	hSpCas9	positive selection	3843891
44235384	44235407	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000160223	-0.033753027195335	[5]	[4,3]	0	hSpCas9	positive selection	3843892
5028091	5028114	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCGCATGTTCAAGAAGACGG	ICOSLG	ENSG00000277117	-0.033753027195335	[5]	[4,3]	0	hSpCas9	positive selection	3843893
5022678	5022701	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000277117	0.013781898313037388	[4]	[3,4]	0	hSpCas9	positive selection	3843894
44240797	44240820	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGCTCACCTGCCCAGCCGCATGG	ICOSLG	ENSG00000160223	0.013781898313037388	[4]	[3,4]	0	hSpCas9	positive selection	3843895
44235498	44235521	21	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000160223	0.26292127277926725	[6]	[6,6]	7	hSpCas9	positive selection	3843896
5027977	5028000	21	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGAAGGTGAGCTCATCCTGGG	ICOSLG	ENSG00000277117	0.26292127277926725	[6]	[6,6]	7	hSpCas9	positive selection	3843897
44235357	44235380	21	-	26780180	A375	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	1.12048112810593	[]	[]	5	hSpCas9	negative selection	3949874
44231361	44231384	21	-	26780180	A375	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	1.40342234682698	[]	[]	7	hSpCas9	negative selection	3949875
44238451	44238474	21	+	26780180	A375	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	1.04102472212687	[]	[]	5	hSpCas9	negative selection	3949876
44238447	44238470	21	-	26780180	A375	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.95356872360506	[]	[]	4	hSpCas9	negative selection	3949877
44235447	44235470	21	+	26780180	A375	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	1.03689837131344	[]	[]	5	hSpCas9	negative selection	3949878
44231279	44231302	21	-	26780180	A375	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	1.09272707188599	[]	[]	5	hSpCas9	negative selection	3949879
44235357	44235380	21	-	26780180	HT29	viability (GeCKOv2 library)	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	1.09209057348108	[]	[]	5	hSpCas9	negative selection	4057840
44231361	44231384	21	-	26780180	HT29	viability (GeCKOv2 library)	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	1.01841542185111	[]	[]	4	hSpCas9	negative selection	4057841
44238451	44238474	21	+	26780180	HT29	viability (GeCKOv2 library)	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	1.27766480648818	[]	[]	6	hSpCas9	negative selection	4057842
44238447	44238470	21	-	26780180	HT29	viability (GeCKOv2 library)	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.699476204574425	[]	[]	2	hSpCas9	negative selection	4057843
44235447	44235470	21	+	26780180	HT29	viability (GeCKOv2 library)	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.760037638976057	[]	[]	3	hSpCas9	negative selection	4057844
44231279	44231302	21	-	26780180	HT29	viability (GeCKOv2 library)	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	1.09396901558608	[]	[]	5	hSpCas9	negative selection	4057845
5028147	5028170	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000277117	0.04689829848637733	[2]	[2,1]	1	hSpCas9	positive selection	4143850
5025024	5025047	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000277117	-0.30631629102846053	[2]	[0,1]	-6	hSpCas9	positive selection	4143851
44238447	44238470	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.4732018419326631	[2]	[1,2]	8	hSpCas9	positive selection	4143852
5028047	5028070	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	-0.06967378557023528	[3]	[1,2]	-2	hSpCas9	positive selection	4143853
5028147	5028170	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGACCCCCAGCGTGAACATTGG	ICOSLG	ENSG00000277117	0.23708990843305738	[2]	[1,2,0,0]	1	hSpCas9	positive selection	4207872
5025024	5025047	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000277117	0.7979754288379652	[1]	[2,0,1,0]	5	hSpCas9	positive selection	4207873
44238447	44238470	21	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	1.053600414958836	[2]	[0,0,0,4]	7	hSpCas9	positive selection	4207874
5028047	5028070	21	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.3642512935194496	[3]	[2,3,3,0]	2	hSpCas9	positive selection	4207875
44235447	44235470	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.1735296405383875	[3]	[2,1]	-4	hSpCas9	positive selection	4276197
44235357	44235380	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.33419739792861974	[2]	[3,2]	6	hSpCas9	positive selection	4276198
44231361	44231384	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.20886158143102085	[2]	[2,2]	4	hSpCas9	positive selection	4276199
44231279	44231302	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.06838765341852104	[3]	[3,2]	1	hSpCas9	positive selection	4340455
44238447	44238470	21	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.45913193151836357	[2]	[1,0]	-7	hSpCas9	positive selection	4340456
44238451	44238474	21	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.6255313658220762	[1]	[0,0]	-8	hSpCas9	positive selection	4340457
44235323	44235345	21	+	27760321	OCIAML3	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.0987855159387881	[629,442]	[515,350]	1	hSpCas9	negative selection	4408643
5028153	5028175	21	-	27760321	OCIAML3	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.0987855159387881	[629,442]	[515,350]	1	hSpCas9	negative selection	4408644
5028128	5028150	21	+	27760321	OCIAML3	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.5646383685568448	[479,499]	[510,645]	6	hSpCas9	negative selection	4408645
44235348	44235370	21	-	27760321	OCIAML3	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.5646383685568448	[479,499]	[510,645]	6	hSpCas9	negative selection	4408646
5028105	5028127	21	+	27760321	OCIAML3	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.6690516525979506	[606,462]	[218,315]	-6	hSpCas9	negative selection	4408647
44235371	44235393	21	-	27760321	OCIAML3	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.6690516525979506	[606,462]	[218,315]	-6	hSpCas9	negative selection	4408648
44235448	44235470	21	+	27760321	OCIAML3	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.48079594715384233	[166,192]	[116,81]	-5	hSpCas9	negative selection	4408649
5028028	5028050	21	-	27760321	OCIAML3	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-0.48079594715384233	[166,192]	[116,81]	-5	hSpCas9	negative selection	4408650
5028005	5028027	21	+	27760321	OCIAML3	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.28807387480573465	[475,410]	[427,414]	3	hSpCas9	negative selection	4408651
44235471	44235493	21	-	27760321	OCIAML3	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.28807387480573465	[475,410]	[427,414]	3	hSpCas9	negative selection	4408652
44235323	44235345	21	+	27760321	OCIAML2	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	-0.43611856888524086	[629,442]	[280,364]	-5	hSpCas9	negative selection	4492106
5028153	5028175	21	-	27760321	OCIAML2	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	-0.43611856888524086	[629,442]	[280,364]	-5	hSpCas9	negative selection	4492107
5028128	5028150	21	+	27760321	OCIAML2	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.5990366810270171	[479,499]	[545,678]	7	hSpCas9	negative selection	4492108
44235348	44235370	21	-	27760321	OCIAML2	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.5990366810270171	[479,499]	[545,678]	7	hSpCas9	negative selection	4492109
5028105	5028127	21	+	27760321	OCIAML2	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.8994799938907734	[606,462]	[240,215]	-7	hSpCas9	negative selection	4492110
44235371	44235393	21	-	27760321	OCIAML2	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.8994799938907734	[606,462]	[240,215]	-7	hSpCas9	negative selection	4492111
44235448	44235470	21	+	27760321	OCIAML2	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.15992257309222868	[166,192]	[115,151]	-2	hSpCas9	negative selection	4492112
5028028	5028050	21	-	27760321	OCIAML2	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-0.15992257309222868	[166,192]	[115,151]	-2	hSpCas9	negative selection	4492113
5028005	5028027	21	+	27760321	OCIAML2	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.1769839614623624	[475,410]	[290,553]	2	hSpCas9	negative selection	4492114
44235471	44235493	21	-	27760321	OCIAML2	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.1769839614623624	[475,410]	[290,553]	2	hSpCas9	negative selection	4492115
44235323	44235345	21	+	27760321	MV411	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.7503169318572547	[629,442]	[568,618]	5	hSpCas9	negative selection	4575569
5028153	5028175	21	-	27760321	MV411	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.7503169318572547	[629,442]	[568,618]	5	hSpCas9	negative selection	4575570
5028128	5028150	21	+	27760321	MV411	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	1.5545212983816208	[479,499]	[1087,753]	9	hSpCas9	negative selection	4575571
44235348	44235370	21	-	27760321	MV411	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	1.5545212983816208	[479,499]	[1087,753]	9	hSpCas9	negative selection	4575572
5028105	5028127	21	+	27760321	MV411	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.2677866640568957	[606,462]	[244,359]	-2	hSpCas9	negative selection	4575573
44235371	44235393	21	-	27760321	MV411	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.2677866640568957	[606,462]	[244,359]	-2	hSpCas9	negative selection	4575574
44235448	44235470	21	+	27760321	MV411	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.9700939670830804	[166,192]	[275,172]	7	hSpCas9	negative selection	4575575
5028028	5028050	21	-	27760321	MV411	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	0.9700939670830804	[166,192]	[275,172]	7	hSpCas9	negative selection	4575576
5028005	5028027	21	+	27760321	MV411	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.2596097154119983	[475,410]	[360,331]	1	hSpCas9	negative selection	4575577
44235471	44235493	21	-	27760321	MV411	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.2596097154119983	[475,410]	[360,331]	1	hSpCas9	negative selection	4575578
44235323	44235345	21	+	27760321	HL60	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	-0.2468422593951785	[629,442]	[257,478]	-3	hSpCas9	negative selection	4659032
5028153	5028175	21	-	27760321	HL60	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	-0.2468422593951785	[629,442]	[257,478]	-3	hSpCas9	negative selection	4659033
5028128	5028150	21	+	27760321	HL60	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.6679606132681994	[479,499]	[675,599]	7	hSpCas9	negative selection	4659034
44235348	44235370	21	-	27760321	HL60	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.6679606132681994	[479,499]	[675,599]	7	hSpCas9	negative selection	4659035
5028105	5028127	21	+	27760321	HL60	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.4172921083652642	[606,462]	[331,316]	-5	hSpCas9	negative selection	4659036
44235371	44235393	21	-	27760321	HL60	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.4172921083652642	[606,462]	[331,316]	-5	hSpCas9	negative selection	4659037
44235448	44235470	21	+	27760321	HL60	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.22428152954739144	[166,192]	[184,160]	2	hSpCas9	negative selection	4659038
5028028	5028050	21	-	27760321	HL60	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	0.22428152954739144	[166,192]	[184,160]	2	hSpCas9	negative selection	4659039
5028005	5028027	21	+	27760321	HL60	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.11405058966941571	[475,410]	[374,407]	1	hSpCas9	negative selection	4659040
44235471	44235493	21	-	27760321	HL60	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.11405058966941571	[475,410]	[374,407]	1	hSpCas9	negative selection	4659041
44235323	44235345	21	+	27760321	HT1080	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	1.185212193968554	[442,345]	[354,359]	6	hSpCas9	negative selection	4742495
5028153	5028175	21	-	27760321	HT1080	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	1.185212193968554	[442,345]	[354,359]	6	hSpCas9	negative selection	4742496
5028128	5028150	21	+	27760321	HT1080	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	-0.8780899061858836	[499,389]	[126,62]	-4	hSpCas9	negative selection	4742497
44235348	44235370	21	-	27760321	HT1080	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	-0.8780899061858836	[499,389]	[126,62]	-4	hSpCas9	negative selection	4742498
5028105	5028127	21	+	27760321	HT1080	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.7309157590211388	[462,360]	[106,89]	-3	hSpCas9	negative selection	4742499
44235371	44235393	21	-	27760321	HT1080	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.7309157590211388	[462,360]	[106,89]	-3	hSpCas9	negative selection	4742500
44235448	44235470	21	+	27760321	HT1080	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.9508328611219243	[192,150]	[44,24]	-4	hSpCas9	negative selection	4742501
5028028	5028050	21	-	27760321	HT1080	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-0.9508328611219243	[192,150]	[44,24]	-4	hSpCas9	negative selection	4742502
5028005	5028027	21	+	27760321	HT1080	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	1.6552905085055816	[410,320]	[264,671]	8	hSpCas9	negative selection	4742503
44235471	44235493	21	-	27760321	HT1080	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	1.6552905085055816	[410,320]	[264,671]	8	hSpCas9	negative selection	4742504
44235323	44235345	21	+	27760321	HT29	viability after 7 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.670984038025815	[442,345]	[999,702,747]	8	hSpCas9	negative selection	4825958
5028153	5028175	21	-	27760321	HT29	viability after 7 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.670984038025815	[442,345]	[999,702,747]	8	hSpCas9	negative selection	4825959
5028128	5028150	21	+	27760321	HT29	viability after 7 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.3325181125988787	[499,389]	[1027,516,660]	5	hSpCas9	negative selection	4825960
44235348	44235370	21	-	27760321	HT29	viability after 7 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.3325181125988787	[499,389]	[1027,516,660]	5	hSpCas9	negative selection	4825961
5028105	5028127	21	+	27760321	HT29	viability after 7 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.3532290542745222	[462,360]	[994,488,592]	5	hSpCas9	negative selection	4825962
44235371	44235393	21	-	27760321	HT29	viability after 7 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.3532290542745222	[462,360]	[994,488,592]	5	hSpCas9	negative selection	4825963
44235448	44235470	21	+	27760321	HT29	viability after 7 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.7489954548873354	[192,150]	[91,197,99]	-8	hSpCas9	negative selection	4825964
5028028	5028050	21	-	27760321	HT29	viability after 7 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-0.7489954548873354	[192,150]	[91,197,99]	-8	hSpCas9	negative selection	4825965
5028005	5028027	21	+	27760321	HT29	viability after 7 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.45412659065544014	[410,320]	[943,583,453]	7	hSpCas9	negative selection	4825966
44235471	44235493	21	-	27760321	HT29	viability after 7 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.45412659065544014	[410,320]	[943,583,453]	7	hSpCas9	negative selection	4825967
44235323	44235345	21	+	27760321	HT29	viability after 25 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.9371754025362931	[442,345]	[703,898,1010]	9	hSpCas9	negative selection	4909421
5028153	5028175	21	-	27760321	HT29	viability after 25 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.9371754025362931	[442,345]	[703,898,1010]	9	hSpCas9	negative selection	4909422
5028128	5028150	21	+	27760321	HT29	viability after 25 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.5335150762754846	[499,389]	[754,610,851]	6	hSpCas9	negative selection	4909423
44235348	44235370	21	-	27760321	HT29	viability after 25 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.5335150762754846	[499,389]	[754,610,851]	6	hSpCas9	negative selection	4909424
5028105	5028127	21	+	27760321	HT29	viability after 25 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.10806516747385728	[462,360]	[355,607,573]	1	hSpCas9	negative selection	4909425
44235371	44235393	21	-	27760321	HT29	viability after 25 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.10806516747385728	[462,360]	[355,607,573]	1	hSpCas9	negative selection	4909426
44235448	44235470	21	+	27760321	HT29	viability after 25 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.6984457433762652	[192,150]	[111,68,189]	-5	hSpCas9	negative selection	4909427
5028028	5028050	21	-	27760321	HT29	viability after 25 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-0.6984457433762652	[192,150]	[111,68,189]	-5	hSpCas9	negative selection	4909428
5028005	5028027	21	+	27760321	HT29	viability after 25 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.26332806651300505	[410,320]	[444,423,655]	2	hSpCas9	negative selection	4909429
44235471	44235493	21	-	27760321	HT29	viability after 25 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.26332806651300505	[410,320]	[444,423,655]	2	hSpCas9	negative selection	4909430
44235323	44235345	21	+	27760321	HT29	viability after 22 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	1.2913715612867287	[442,345]	[1314,1174,850]	9	hSpCas9	negative selection	4992884
5028153	5028175	21	-	27760321	HT29	viability after 22 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	1.2913715612867287	[442,345]	[1314,1174,850]	9	hSpCas9	negative selection	4992885
5028128	5028150	21	+	27760321	HT29	viability after 22 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.5058257428952555	[499,389]	[467,728,1003]	5	hSpCas9	negative selection	4992886
44235348	44235370	21	-	27760321	HT29	viability after 22 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.5058257428952555	[499,389]	[467,728,1003]	5	hSpCas9	negative selection	4992887
5028105	5028127	21	+	27760321	HT29	viability after 22 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.02745901628847683	[462,360]	[533,401,463]	0	hSpCas9	negative selection	4992888
44235371	44235393	21	-	27760321	HT29	viability after 22 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.02745901628847683	[462,360]	[533,401,463]	0	hSpCas9	negative selection	4992889
44235448	44235470	21	+	27760321	HT29	viability after 22 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-1.0951612241067556	[192,150]	[148,113,13]	-7	hSpCas9	negative selection	4992890
5028028	5028050	21	-	27760321	HT29	viability after 22 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-1.0951612241067556	[192,150]	[148,113,13]	-7	hSpCas9	negative selection	4992891
5028005	5028027	21	+	27760321	HT29	viability after 22 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.23957574585697014	[410,320]	[412,486,601]	2	hSpCas9	negative selection	4992892
44235471	44235493	21	-	27760321	HT29	viability after 22 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.23957574585697014	[410,320]	[412,486,601]	2	hSpCas9	negative selection	4992893
44235323	44235345	21	+	27760321	HT29	viability after 19 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.9104980997747212	[442,345]	[1211,819,560]	8	hSpCas9	negative selection	5076347
5028153	5028175	21	-	27760321	HT29	viability after 19 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.9104980997747212	[442,345]	[1211,819,560]	8	hSpCas9	negative selection	5076348
5028128	5028150	21	+	27760321	HT29	viability after 19 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.7404401398436204	[499,389]	[441,694,1350]	7	hSpCas9	negative selection	5076349
44235348	44235370	21	-	27760321	HT29	viability after 19 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.7404401398436204	[499,389]	[441,694,1350]	7	hSpCas9	negative selection	5076350
5028105	5028127	21	+	27760321	HT29	viability after 19 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.6941174779914167	[462,360]	[341,304,233]	-5	hSpCas9	negative selection	5076351
44235371	44235393	21	-	27760321	HT29	viability after 19 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.6941174779914167	[462,360]	[341,304,233]	-5	hSpCas9	negative selection	5076352
44235448	44235470	21	+	27760321	HT29	viability after 19 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.7178605631958124	[192,150]	[188,109,68]	-5	hSpCas9	negative selection	5076353
5028028	5028050	21	-	27760321	HT29	viability after 19 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-0.7178605631958124	[192,150]	[188,109,68]	-5	hSpCas9	negative selection	5076354
5028005	5028027	21	+	27760321	HT29	viability after 19 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.6979042870959558	[410,320]	[707,419,902]	7	hSpCas9	negative selection	5076355
44235471	44235493	21	-	27760321	HT29	viability after 19 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.6979042870959558	[410,320]	[707,419,902]	7	hSpCas9	negative selection	5076356
44235323	44235345	21	+	27760321	HT29	viability after 16 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.9514993873853046	[442,345]	[865,654,1045]	9	hSpCas9	negative selection	5159810
5028153	5028175	21	-	27760321	HT29	viability after 16 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.9514993873853046	[442,345]	[865,654,1045]	9	hSpCas9	negative selection	5159811
5028128	5028150	21	+	27760321	HT29	viability after 16 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.3270586249474939	[499,389]	[640,472,764]	3	hSpCas9	negative selection	5159812
44235348	44235370	21	-	27760321	HT29	viability after 16 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.3270586249474939	[499,389]	[640,472,764]	3	hSpCas9	negative selection	5159813
5028105	5028127	21	+	27760321	HT29	viability after 16 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.09450765785895637	[462,360]	[270,654,347]	-1	hSpCas9	negative selection	5159814
44235371	44235393	21	-	27760321	HT29	viability after 16 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.09450765785895637	[462,360]	[270,654,347]	-1	hSpCas9	negative selection	5159815
44235448	44235470	21	+	27760321	HT29	viability after 16 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-1.9491801968496592	[192,150]	[52,80,14]	-8	hSpCas9	negative selection	5159816
5028028	5028050	21	-	27760321	HT29	viability after 16 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-1.9491801968496592	[192,150]	[52,80,14]	-8	hSpCas9	negative selection	5159817
5028005	5028027	21	+	27760321	HT29	viability after 16 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.45940239338559946	[410,320]	[640,387,671]	5	hSpCas9	negative selection	5159818
44235471	44235493	21	-	27760321	HT29	viability after 16 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.45940239338559946	[410,320]	[640,387,671]	5	hSpCas9	negative selection	5159819
44235323	44235345	21	+	27760321	HT29	viability after 13 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.6384420413452332	[442,345]	[781,760,600]	8	hSpCas9	negative selection	5243273
5028153	5028175	21	-	27760321	HT29	viability after 13 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.6384420413452332	[442,345]	[781,760,600]	8	hSpCas9	negative selection	5243274
5028128	5028150	21	+	27760321	HT29	viability after 13 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.42211076846183787	[499,389]	[787,565,718]	5	hSpCas9	negative selection	5243275
44235348	44235370	21	-	27760321	HT29	viability after 13 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.42211076846183787	[499,389]	[787,565,718]	5	hSpCas9	negative selection	5243276
5028105	5028127	21	+	27760321	HT29	viability after 13 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.14862847632445617	[462,360]	[513,573,502]	1	hSpCas9	negative selection	5243277
44235371	44235393	21	-	27760321	HT29	viability after 13 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.14862847632445617	[462,360]	[513,573,502]	1	hSpCas9	negative selection	5243278
44235448	44235470	21	+	27760321	HT29	viability after 13 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-1.0899729645801635	[192,150]	[106,93,80]	-7	hSpCas9	negative selection	5243279
5028028	5028050	21	-	27760321	HT29	viability after 13 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-1.0899729645801635	[192,150]	[106,93,80]	-7	hSpCas9	negative selection	5243280
5028005	5028027	21	+	27760321	HT29	viability after 13 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.7433153353973626	[410,320]	[879,763,500]	8	hSpCas9	negative selection	5243281
44235471	44235493	21	-	27760321	HT29	viability after 13 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.7433153353973626	[410,320]	[879,763,500]	8	hSpCas9	negative selection	5243282
44235323	44235345	21	+	27760321	HT29	viability after 10 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	1.0860266370538916	[442,345]	[1290,817,1021]	9	hSpCas9	negative selection	5326736
5028153	5028175	21	-	27760321	HT29	viability after 10 days	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	1.0860266370538916	[442,345]	[1290,817,1021]	9	hSpCas9	negative selection	5326737
5028128	5028150	21	+	27760321	HT29	viability after 10 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	0.604376267375252	[499,389]	[846,745,935]	8	hSpCas9	negative selection	5326738
44235348	44235370	21	-	27760321	HT29	viability after 10 days	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	0.604376267375252	[499,389]	[846,745,935]	8	hSpCas9	negative selection	5326739
5028105	5028127	21	+	27760321	HT29	viability after 10 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.18892742444286517	[462,360]	[745,375,629]	2	hSpCas9	negative selection	5326740
44235371	44235393	21	-	27760321	HT29	viability after 10 days	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.18892742444286517	[462,360]	[745,375,629]	2	hSpCas9	negative selection	5326741
44235448	44235470	21	+	27760321	HT29	viability after 10 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-1.3777178924621498	[192,150]	[83,62,99]	-8	hSpCas9	negative selection	5326742
5028028	5028050	21	-	27760321	HT29	viability after 10 days	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-1.3777178924621498	[192,150]	[83,62,99]	-8	hSpCas9	negative selection	5326743
5028005	5028027	21	+	27760321	HT29	viability after 10 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	0.4451235141973182	[410,320]	[599,443,812]	6	hSpCas9	negative selection	5326744
44235471	44235493	21	-	27760321	HT29	viability after 10 days	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	0.4451235141973182	[410,320]	[599,443,812]	6	hSpCas9	negative selection	5326745
44235323	44235345	21	+	27760321	MOLM13	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000160223	0.13344029841522487	[629,442]	[383,280]	0	hSpCas9	negative selection	5410199
5028153	5028175	21	-	27760321	MOLM13	viability	AGCAGCCAATGTTCACGCTGGG	ICOSLG	ENSG00000277117	0.13344029841522487	[629,442]	[383,280]	0	hSpCas9	negative selection	5410200
5028128	5028150	21	+	27760321	MOLM13	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000277117	1.3573968099043259	[479,499]	[464,921]	8	hSpCas9	negative selection	5410201
44235348	44235370	21	-	27760321	MOLM13	viability	CAGCGTGCTGAGGATCGCACGG	ICOSLG	ENSG00000160223	1.3573968099043259	[479,499]	[464,921]	8	hSpCas9	negative selection	5410202
5028105	5028127	21	+	27760321	MOLM13	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.4307349734349536	[606,462]	[306,149]	-3	hSpCas9	negative selection	5410203
44235371	44235393	21	-	27760321	MOLM13	viability	ATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.4307349734349536	[606,462]	[306,149]	-3	hSpCas9	negative selection	5410204
44235448	44235470	21	+	27760321	MOLM13	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.13360010330824035	[166,192]	[6,166]	-1	hSpCas9	negative selection	5410205
5028028	5028050	21	-	27760321	MOLM13	viability	TTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000277117	-0.13360010330824035	[166,192]	[6,166]	-1	hSpCas9	negative selection	5410206
5028005	5028027	21	+	27760321	MOLM13	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000277117	1.3466230290837817	[475,410]	[659,612]	8	hSpCas9	negative selection	5410207
44235471	44235493	21	-	27760321	MOLM13	viability	ATCCATAAACGGCTACCCCAGG	ICOSLG	ENSG00000160223	1.3466230290837817	[475,410]	[659,612]	8	hSpCas9	negative selection	5410208
44240885	44240908	21	+	27661255	K562	viability	GGCCGCGGGAGACCTCGGAGAGG	ICOSLG	ENSG00000160223	-0.017559236139458784	[755,701]	[561,587]	0	dCas9-KRAB	negative selection	5486022
5022590	5022613	21	-	27661255	K562	viability	GGCCGCGGGAGACCTCGGAGAGG	ICOSLG	ENSG00000277117	-0.017559236139458784	[755,701]	[561,587]	0	dCas9-KRAB	negative selection	5486023
5022882	5022905	21	+	27661255	K562	viability	GGGCCTGGCACCGGGACCCATGG	ICOSLG	ENSG00000277117	0.13236676655695356	[1135,1159]	[1095,926]	4	dCas9-KRAB	negative selection	5486024
44240593	44240616	21	-	27661255	K562	viability	GGGCCTGGCACCGGGACCCATGG	ICOSLG	ENSG00000160223	0.13236676655695356	[1135,1159]	[1095,926]	4	dCas9-KRAB	negative selection	5486025
5022518	5022541	21	+	27661255	K562	viability	GCGCTGGGCGCTCAGAGCCTCGG	ICOSLG	ENSG00000277117	0.027126075947782373	[821,767]	[662,634]	0	dCas9-KRAB	negative selection	5486026
44240957	44240980	21	-	27661255	K562	viability	GCGCTGGGCGCTCAGAGCCTCGG	ICOSLG	ENSG00000160223	0.027126075947782373	[821,767]	[662,634]	0	dCas9-KRAB	negative selection	5486027
44235447	44235470	21	+	27260156	BXPC3	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.0980360583463441	[659]	[662,616,583,717]	-2	hSpCas9	negative selection	5548657
44235357	44235380	21	-	27260156	BXPC3	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.12280703580207142	[361]	[384,323,343,329]	-3	hSpCas9	negative selection	5548658
44231361	44231384	21	-	27260156	BXPC3	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.48754940925666057	[335]	[460,402,545,576]	8	hSpCas9	negative selection	5548659
44231279	44231302	21	-	27260156	BXPC3	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.3078064893279009	[551]	[533,646,938,766]	6	hSpCas9	negative selection	5612915
44238447	44238470	21	-	27260156	BXPC3	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.0719871686025646	[201]	[184,203,278,224]	1	hSpCas9	negative selection	5612916
44238451	44238474	21	+	27260156	BXPC3	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.3914717021432117	[99]	[126,184,96,135]	8	hSpCas9	negative selection	5612917
44235447	44235470	21	+	27260156	A673	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.2088635883954526	[659]	[944,868,925,926]	5	hSpCas9	negative selection	5669908
44235357	44235380	21	-	27260156	A673	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.19088161953195992	[361]	[477,242,445,368]	-5	hSpCas9	negative selection	5669909
44231361	44231384	21	-	27260156	A673	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.46959380151674057	[335]	[615,539,524,559]	9	hSpCas9	negative selection	5669910
44231279	44231302	21	-	27260156	A673	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.025118806175259606	[551]	[665,646,612,681]	0	hSpCas9	negative selection	5734166
44238447	44238470	21	-	27260156	A673	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.3117718033096899	[201]	[398,264,328,217]	7	hSpCas9	negative selection	5734167
44238451	44238474	21	+	27260156	A673	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.28637456074308343	[99]	[108,108,59,117]	-6	hSpCas9	negative selection	5734168
44235447	44235470	21	+	27260156	A375	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.21764685137591433	[659]	[779,1200,943,719]	3	hSpCas9	negative selection	5791159
44235357	44235380	21	-	27260156	A375	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.1568126389458956	[361]	[514,565,380,438]	2	hSpCas9	negative selection	5791160
44231361	44231384	21	-	27260156	A375	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.4821359716979223	[335]	[721,378,497,566]	7	hSpCas9	negative selection	5791161
44231279	44231302	21	-	27260156	A375	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.15592736324265644	[551]	[738,929,576,660]	2	hSpCas9	negative selection	5855417
44238447	44238470	21	-	27260156	A375	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.32328588735944064	[201]	[305,449,110,329]	5	hSpCas9	negative selection	5855418
44238451	44238474	21	+	27260156	A375	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.5889515160085221	[99]	[179,202,212,116]	8	hSpCas9	negative selection	5855419
44235447	44235470	21	+	27260156	COLO741	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.014915871874401854	[659]	[853,820,828]	0	hSpCas9	negative selection	5912410
44235357	44235380	21	-	27260156	COLO741	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.31233913779406586	[361]	[459,320,344]	-6	hSpCas9	negative selection	5912411
44231361	44231384	21	-	27260156	COLO741	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.7689575247135075	[335]	[722,774,696]	9	hSpCas9	negative selection	5912412
44231279	44231302	21	-	27260156	COLO741	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.19233849183306834	[551]	[1128,708,618]	4	hSpCas9	negative selection	5976668
44238447	44238470	21	-	27260156	COLO741	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.06848068562929122	[201]	[315,310,193]	1	hSpCas9	negative selection	5976669
44238451	44238474	21	+	27260156	COLO741	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.13154716439268732	[99]	[150,91,109]	-3	hSpCas9	negative selection	5976670
44235447	44235470	21	+	27260156	CAL120	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.18478698698204016	[659]	[672,712,772]	-3	hSpCas9	negative selection	6033661
44235357	44235380	21	-	27260156	CAL120	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.6665475554667751	[361]	[876,849,446]	8	hSpCas9	negative selection	6033662
44231361	44231384	21	-	27260156	CAL120	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5199301657797597	[335]	[516,673,594]	7	hSpCas9	negative selection	6033663
44231279	44231302	21	-	27260156	CAL120	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.3271282421703051	[551]	[647,781,1117]	5	hSpCas9	negative selection	6097919
44238447	44238470	21	-	27260156	CAL120	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.30415262280168653	[201]	[382,366,193]	4	hSpCas9	negative selection	6097920
44238451	44238474	21	+	27260156	CAL120	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.3356525688456393	[99]	[240,47,193]	5	hSpCas9	negative selection	6097921
44235447	44235470	21	+	27260156	CADOES1	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.1828852085625467	[659]	[553,581,411,617]	-3	hSpCas9	negative selection	6154912
44235357	44235380	21	-	27260156	CADOES1	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.445592842527879	[361]	[308,169,250,258]	-7	hSpCas9	negative selection	6154913
44231361	44231384	21	-	27260156	CADOES1	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.592510704580353	[335]	[468,328,449,642]	8	hSpCas9	negative selection	6154914
44231279	44231302	21	-	27260156	CADOES1	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.2521554388159949	[551]	[497,346,521,353]	-4	hSpCas9	negative selection	6219170
44238447	44238470	21	-	27260156	CADOES1	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.3516884177446583	[201]	[334,177,194,250]	6	hSpCas9	negative selection	6219171
44238451	44238474	21	+	27260156	CADOES1	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.5080057307809449	[99]	[135,160,127,102]	8	hSpCas9	negative selection	6219172
44235447	44235470	21	+	27260156	EWS502	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.009351720039844635	[659]	[495,806,628,874]	0	hSpCas9	negative selection	6276163
44235357	44235380	21	-	27260156	EWS502	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.0777665740885286	[361]	[176,462,391,625]	1	hSpCas9	negative selection	6276164
44231361	44231384	21	-	27260156	EWS502	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.483322074900001	[335]	[408,552,539,494]	8	hSpCas9	negative selection	6276165
44231279	44231302	21	-	27260156	EWS502	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.13468112138174848	[551]	[566,565,602,855]	2	hSpCas9	negative selection	6340421
44238447	44238470	21	-	27260156	EWS502	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.5558598270773023	[201]	[240,284,388,355]	8	hSpCas9	negative selection	6340422
44238451	44238474	21	+	27260156	EWS502	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.3365105185047268	[99]	[104,208,121,95]	6	hSpCas9	negative selection	6340423
44235447	44235470	21	+	27260156	EW8	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.14012151550242724	[659]	[809,549,520,510]	2	hSpCas9	negative selection	6397414
44235357	44235380	21	-	27260156	EW8	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.396397206893376	[361]	[244,194,217,235]	-6	hSpCas9	negative selection	6397415
44231361	44231384	21	-	27260156	EW8	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.9594602208023953	[335]	[316,389,369,1040]	9	hSpCas9	negative selection	6397416
44231279	44231302	21	-	27260156	EW8	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.051773648565248576	[551]	[583,447,312,546]	0	hSpCas9	negative selection	6461672
44238447	44238470	21	-	27260156	EW8	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.44728977581960483	[201]	[293,261,171,180]	7	hSpCas9	negative selection	6461673
44238451	44238474	21	+	27260156	EW8	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.1701097471683104	[99]	[32,121,127,68]	3	hSpCas9	negative selection	6461674
44235447	44235470	21	+	27260156	CORL105	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.106817314922657	[659]	[813,779,919,827]	2	hSpCas9	negative selection	6518665
44235357	44235380	21	-	27260156	CORL105	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.16853782443199652	[361]	[478,383,553,501]	3	hSpCas9	negative selection	6518666
44231361	44231384	21	-	27260156	CORL105	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5131988133827049	[335]	[488,519,584,652]	8	hSpCas9	negative selection	6518667
44231279	44231302	21	-	27260156	CORL105	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.06201000454583783	[551]	[760,566,754,632]	1	hSpCas9	negative selection	6582923
44238447	44238470	21	-	27260156	CORL105	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.27406560320262974	[201]	[320,206,352,275]	5	hSpCas9	negative selection	6582924
44238451	44238474	21	+	27260156	CORL105	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.8042888067910234	[99]	[35,77,105,52]	-8	hSpCas9	negative selection	6582925
44235447	44235470	21	+	27260156	HS294T	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.337443829609283	[659]	[361,241,358,324]	4	hSpCas9	negative selection	6639916
44235357	44235380	21	-	27260156	HS294T	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.405161840666088	[361]	[136,139,279,190]	5	hSpCas9	negative selection	6639917
44231361	44231384	21	-	27260156	HS294T	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.6440353484387629	[335]	[130,209,249,231]	8	hSpCas9	negative selection	6639918
44231279	44231302	21	-	27260156	HS294T	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.010904554125670152	[551]	[175,169,197,341]	0	hSpCas9	negative selection	6704174
44238447	44238470	21	-	27260156	HS294T	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.02124890936274504	[201]	[101,61,62,78]	0	hSpCas9	negative selection	6704175
44238451	44238474	21	+	27260156	HS294T	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.20769638149240288	[99]	[26,14,29,68]	-3	hSpCas9	negative selection	6704176
44235447	44235470	21	+	27260156	HCC44	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.2872527012851801	[659]	[1170,657,1113,791]	4	hSpCas9	negative selection	6761167
44235357	44235380	21	-	27260156	HCC44	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.27485386734684425	[361]	[476,328,671,549]	4	hSpCas9	negative selection	6761168
44231361	44231384	21	-	27260156	HCC44	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5417119176748251	[335]	[549,363,693,647]	8	hSpCas9	negative selection	6761169
44231279	44231302	21	-	27260156	HCC44	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.09610807773153601	[551]	[629,420,950,739]	1	hSpCas9	negative selection	6825425
44238447	44238470	21	-	27260156	HCC44	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.06404756210897933	[201]	[303,138,277,181]	-1	hSpCas9	negative selection	6825426
44238451	44238474	21	+	27260156	HCC44	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.03537487541593354	[99]	[182,94,170,34]	0	hSpCas9	negative selection	6825427
44235447	44235470	21	+	27260156	G402	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.19785842292942668	[659]	[738,525,1018,1336]	2	hSpCas9	negative selection	6882418
44235357	44235380	21	-	27260156	G402	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.16898510997300542	[361]	[309,507,231,508]	-2	hSpCas9	negative selection	6882419
44231361	44231384	21	-	27260156	G402	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.3680081947669982	[335]	[494,367,768,470]	4	hSpCas9	negative selection	6882420
44231279	44231302	21	-	27260156	G402	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.3614232153637871	[551]	[397,880,922,1173]	4	hSpCas9	negative selection	6946676
44238447	44238470	21	-	27260156	G402	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.8792301592668949	[201]	[371,297,498,613]	9	hSpCas9	negative selection	6946677
44238451	44238474	21	+	27260156	G402	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.9162367438336245	[99]	[69,90,62,37]	-8	hSpCas9	negative selection	6946678
44235447	44235470	21	+	27260156	L33	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.13943065742635674	[659]	[817,281,452,678]	3	hSpCas9	negative selection	7003669
44235357	44235380	21	-	27260156	L33	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.4989774344546357	[361]	[536,267,268,426]	8	hSpCas9	negative selection	7003670
44231361	44231384	21	-	27260156	L33	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.6181930486467082	[335]	[485,241,235,609]	9	hSpCas9	negative selection	7003671
44231279	44231302	21	-	27260156	L33	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.025931809868820405	[551]	[545,217,382,481]	0	hSpCas9	negative selection	7067927
44238447	44238470	21	-	27260156	L33	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.08516815054471372	[201]	[189,96,122,234]	2	hSpCas9	negative selection	7067928
44238451	44238474	21	+	27260156	L33	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.02866949353070991	[99]	[119,45,54,71]	0	hSpCas9	negative selection	7067929
44235447	44235470	21	+	27260156	K562	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.17363310847396207	[659]	[588,644,870,541]	2	hSpCas9	negative selection	7124920
44235357	44235380	21	-	27260156	K562	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.7788519754129963	[361]	[62,269,171,231]	-7	hSpCas9	negative selection	7124921
44231361	44231384	21	-	27260156	K562	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.9154491414511571	[335]	[352,857,475,558]	9	hSpCas9	negative selection	7124922
44231279	44231302	21	-	27260156	K562	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.007928627144557054	[551]	[532,473,467,475]	0	hSpCas9	negative selection	7189178
44238447	44238470	21	-	27260156	K562	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.09101441143322897	[201]	[74,165,191,224]	-1	hSpCas9	negative selection	7189179
44238451	44238474	21	+	27260156	K562	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.7859698858751456	[99]	[35,130,113,301]	8	hSpCas9	negative selection	7189180
44235447	44235470	21	+	27260156	HT29	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.03532808577507818	[659]	[723,990,817,763]	0	hSpCas9	negative selection	7246171
44235357	44235380	21	-	27260156	HT29	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.2769558759212092	[361]	[408,370,460,229]	-5	hSpCas9	negative selection	7246172
44231361	44231384	21	-	27260156	HT29	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.49845661173705863	[335]	[549,695,578,496]	8	hSpCas9	negative selection	7246173
44231279	44231302	21	-	27260156	HT29	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.08284855159928767	[551]	[910,628,622,685]	1	hSpCas9	negative selection	7310429
44238447	44238470	21	-	27260156	HT29	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.11354082478402794	[201]	[251,262,274,268]	2	hSpCas9	negative selection	7310430
44238451	44238474	21	+	27260156	HT29	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.042594633343943755	[99]	[154,117,169,65]	0	hSpCas9	negative selection	7310431
44235447	44235470	21	+	27260156	MHHES1	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.024426316668320958	[659]	[694,768,772,680]	0	hSpCas9	negative selection	7367422
44235357	44235380	21	-	27260156	MHHES1	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.1061296179056142	[361]	[328,386,404,379]	-2	hSpCas9	negative selection	7367423
44231361	44231384	21	-	27260156	MHHES1	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.6600997044807356	[335]	[647,606,690,469]	9	hSpCas9	negative selection	7367424
44231279	44231302	21	-	27260156	MHHES1	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.030693012136675857	[551]	[655,652,401,696]	0	hSpCas9	negative selection	7431680
44238447	44238470	21	-	27260156	MHHES1	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.5342245221038823	[201]	[433,539,239,167]	8	hSpCas9	negative selection	7431681
44238451	44238474	21	+	27260156	MHHES1	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.04523243800002419	[99]	[122,111,66,128]	-1	hSpCas9	negative selection	7431682
44235447	44235470	21	+	27260156	MEWO	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.05170707235919114	[659]	[827,493,634]	1	hSpCas9	negative selection	7488673
44235357	44235380	21	-	27260156	MEWO	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.20753792374879243	[361]	[564,354,286]	4	hSpCas9	negative selection	7488674
44231361	44231384	21	-	27260156	MEWO	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5369193414276004	[335]	[515,403,459]	9	hSpCas9	negative selection	7488675
44231279	44231302	21	-	27260156	MEWO	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.19594268680586785	[551]	[610,653,512]	4	hSpCas9	negative selection	7552931
44238447	44238470	21	-	27260156	MEWO	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.5629904123899561	[201]	[215,333,274]	9	hSpCas9	negative selection	7552932
44238451	44238474	21	+	27260156	MEWO	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.5852232687916261	[99]	[216,118,99]	9	hSpCas9	negative selection	7552933
44235447	44235470	21	+	27260156	LNCAPCLONEFGC	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.29333379657000846	[659]	[744,603,749,841]	4	hSpCas9	negative selection	7609924
44235357	44235380	21	-	27260156	LNCAPCLONEFGC	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.17019496387455166	[361]	[347,427,441,264]	2	hSpCas9	negative selection	7609925
44231361	44231384	21	-	27260156	LNCAPCLONEFGC	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.8380245797082199	[335]	[625,417,673,483]	9	hSpCas9	negative selection	7609926
44231279	44231302	21	-	27260156	LNCAPCLONEFGC	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.11608396725991005	[551]	[507,556,615,496]	1	hSpCas9	negative selection	7674182
44238447	44238470	21	-	27260156	LNCAPCLONEFGC	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.15279022510772955	[201]	[143,154,202,162]	-2	hSpCas9	negative selection	7674183
44238451	44238474	21	+	27260156	LNCAPCLONEFGC	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.22120401284960334	[99]	[119,74,84,140]	3	hSpCas9	negative selection	7674184
44235447	44235470	21	+	27260156	PANC0327	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.09711676810638381	[659]	[602,628,622,650]	1	hSpCas9	negative selection	7731175
44235357	44235380	21	-	27260156	PANC0327	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.06777083845170101	[361]	[333,255,259,507]	1	hSpCas9	negative selection	7731176
44231361	44231384	21	-	27260156	PANC0327	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.3484245866517348	[335]	[291,468,289,449]	5	hSpCas9	negative selection	7731177
44231279	44231302	21	-	27260156	PANC0327	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.05665676725767127	[551]	[709,250,699,428]	0	hSpCas9	negative selection	7795433
44238447	44238470	21	-	27260156	PANC0327	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.5095215371889898	[201]	[194,336,153,319]	7	hSpCas9	negative selection	7795434
44238451	44238474	21	+	27260156	PANC0327	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.31332287229361366	[99]	[134,56,52,47]	-4	hSpCas9	negative selection	7795435
44235447	44235470	21	+	27260156	NCIH2009	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.2773914494002826	[659]	[1396,1126,881]	4	hSpCas9	negative selection	7852426
44235357	44235380	21	-	27260156	NCIH2009	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.3265985292931498	[361]	[947,508,508]	4	hSpCas9	negative selection	7852427
44231361	44231384	21	-	27260156	NCIH2009	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.7777829620248999	[335]	[867,787,769]	9	hSpCas9	negative selection	7852428
44231279	44231302	21	-	27260156	NCIH2009	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.02052080594571043	[551]	[1100,699,608]	0	hSpCas9	negative selection	7916684
44238447	44238470	21	-	27260156	NCIH2009	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.06016699061986741	[201]	[369,229,231]	-1	hSpCas9	negative selection	7916685
44238451	44238474	21	+	27260156	NCIH2009	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.856900533517851	[99]	[278,243,240]	9	hSpCas9	negative selection	7916686
44235447	44235470	21	+	27260156	NCIH1373	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.06839592493906044	[659]	[1212,622,725,160]	0	hSpCas9	negative selection	7973677
44235357	44235380	21	-	27260156	NCIH1373	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.2385071959746875	[361]	[452,357,251,85]	-2	hSpCas9	negative selection	7973678
44231361	44231384	21	-	27260156	NCIH1373	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	1.1803289047119476	[335]	[1128,839,741,193]	9	hSpCas9	negative selection	7973679
44231279	44231302	21	-	27260156	NCIH1373	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.27903082868303486	[551]	[1178,577,647,177]	2	hSpCas9	negative selection	8037935
44238447	44238470	21	-	27260156	NCIH1373	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.22341055313496028	[201]	[644,169,125,47]	2	hSpCas9	negative selection	8037936
44238451	44238474	21	+	27260156	NCIH1373	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.17687048398886063	[99]	[179,48,47,36]	-2	hSpCas9	negative selection	8037937
44235447	44235470	21	+	27260156	PATU8902	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.12202497833168124	[659]	[872,818,1320,883]	1	hSpCas9	negative selection	8094928
44235357	44235380	21	-	27260156	PATU8902	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.53632205815173	[361]	[842,970,397,800]	5	hSpCas9	negative selection	8094929
44231361	44231384	21	-	27260156	PATU8902	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.721208755157947	[335]	[914,721,730,712]	7	hSpCas9	negative selection	8094930
44231279	44231302	21	-	27260156	PATU8902	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.23354845672162672	[551]	[945,606,699,1474]	2	hSpCas9	negative selection	8159186
44238447	44238470	21	-	27260156	PATU8902	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.9199200979606155	[201]	[571,696,189,784]	8	hSpCas9	negative selection	8159187
44238451	44238474	21	+	27260156	PATU8902	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.3032592356460011	[99]	[91,132,114,109]	-3	hSpCas9	negative selection	8159188
44235447	44235470	21	+	27260156	PANC1	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.2880828390577195	[659]	[604,902,769,548]	4	hSpCas9	negative selection	8216179
44235357	44235380	21	-	27260156	PANC1	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.1629760140034069	[361]	[240,382,297,216]	-3	hSpCas9	negative selection	8216180
44231361	44231384	21	-	27260156	PANC1	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.743882783524923	[335]	[526,552,337,513]	9	hSpCas9	negative selection	8216181
44231279	44231302	21	-	27260156	PANC1	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.1177276275370881	[551]	[390,550,444,648]	1	hSpCas9	negative selection	8280437
44238447	44238470	21	-	27260156	PANC1	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.20769312961128183	[201]	[122,149,187,139]	-3	hSpCas9	negative selection	8280438
44238451	44238474	21	+	27260156	PANC1	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.6979837633177817	[99]	[109,331,90,72]	9	hSpCas9	negative selection	8280439
44235447	44235470	21	+	27260156	PANC0813	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.20462444228418086	[659]	[1008,795,732,1035]	3	hSpCas9	negative selection	8337430
44235357	44235380	21	-	27260156	PANC0813	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.1563863376446496	[361]	[521,381,511,482]	2	hSpCas9	negative selection	8337431
44231361	44231384	21	-	27260156	PANC0813	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5676957206794292	[335]	[514,732,516,567]	8	hSpCas9	negative selection	8337432
44231279	44231302	21	-	27260156	PANC0813	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.11517476857770814	[551]	[914,754,772,401]	2	hSpCas9	negative selection	8401688
44238447	44238470	21	-	27260156	PANC0813	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	-0.39194412307491144	[201]	[237,159,197,134]	-6	hSpCas9	negative selection	8401689
44238451	44238474	21	+	27260156	PANC0813	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.5303644365448856	[99]	[101,62,78,82]	-7	hSpCas9	negative selection	8401690
44235447	44235470	21	+	27260156	RDES	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.24005255149065602	[659]	[503,525,859,723]	-4	hSpCas9	negative selection	8458681
44235357	44235380	21	-	27260156	RDES	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.393628441116198	[361]	[305,196,286,509]	-6	hSpCas9	negative selection	8458682
44231361	44231384	21	-	27260156	RDES	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5527338552328157	[335]	[496,564,607,600]	8	hSpCas9	negative selection	8458683
44231279	44231302	21	-	27260156	RDES	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.03478388086011153	[551]	[498,606,720,671]	0	hSpCas9	negative selection	8522939
44238447	44238470	21	-	27260156	RDES	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.17480860451579172	[201]	[258,235,243,310]	3	hSpCas9	negative selection	8522940
44238451	44238474	21	+	27260156	RDES	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.15332255094571368	[99]	[114,150,158,75]	2	hSpCas9	negative selection	8522941
44235447	44235470	21	+	27260156	PC3	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.2868356445177659	[659]	[533,1077,1086,630]	6	hSpCas9	negative selection	8579932
44235357	44235380	21	-	27260156	PC3	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.03912824506611745	[361]	[228,453,367,371]	-1	hSpCas9	negative selection	8579933
44231361	44231384	21	-	27260156	PC3	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.676275362801338	[335]	[227,480,1243,566]	9	hSpCas9	negative selection	8579934
44231279	44231302	21	-	27260156	PC3	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.09408617846099765	[551]	[307,525,712,638]	-2	hSpCas9	negative selection	8644190
44238447	44238470	21	-	27260156	PC3	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.6636115421778978	[201]	[295,296,371,296]	9	hSpCas9	negative selection	8644191
44238451	44238474	21	+	27260156	PC3	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.5060251572607872	[99]	[30,62,116,101]	-8	hSpCas9	negative selection	8644192
44235447	44235470	21	+	27260156	PATU8988T	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.28424434533587606	[659]	[714,451,474,439]	-5	hSpCas9	negative selection	8701183
44235357	44235380	21	-	27260156	PATU8988T	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.10094347247010432	[361]	[399,286,194,428]	-2	hSpCas9	negative selection	8701184
44231361	44231384	21	-	27260156	PATU8988T	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.375695575843328	[335]	[536,537,240,378]	6	hSpCas9	negative selection	8701185
44231279	44231302	21	-	27260156	PATU8988T	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.03622857552459241	[551]	[724,523,496,430]	0	hSpCas9	negative selection	8765441
44238447	44238470	21	-	27260156	PATU8988T	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.2102817148070164	[201]	[96,240,212,364]	3	hSpCas9	negative selection	8765442
44238451	44238474	21	+	27260156	PATU8988T	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.08157584561414977	[99]	[78,135,51,103]	-1	hSpCas9	negative selection	8765443
44235447	44235470	21	+	27260156	T47D	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.09027109361620755	[659]	[830,833,850,753]	2	hSpCas9	negative selection	8822434
44235357	44235380	21	-	27260156	T47D	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.16870303092294237	[361]	[408,367,405,315]	-4	hSpCas9	negative selection	8822435
44231361	44231384	21	-	27260156	T47D	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5593282129438811	[335]	[600,555,574,576]	9	hSpCas9	negative selection	8822436
44231279	44231302	21	-	27260156	T47D	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.07306792391627315	[551]	[654,593,568,629]	-2	hSpCas9	negative selection	8886692
44238447	44238470	21	-	27260156	T47D	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.27601619117933285	[201]	[279,263,292,304]	6	hSpCas9	negative selection	8886693
44238451	44238474	21	+	27260156	T47D	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.1107918800066976	[99]	[168,106,109,118]	2	hSpCas9	negative selection	8886694
44235447	44235470	21	+	27260156	SU8686	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.1927884028671355	[659]	[681,827,788,672]	3	hSpCas9	negative selection	8943685
44235357	44235380	21	-	27260156	SU8686	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.34289602566502014	[361]	[452,336,546,506]	6	hSpCas9	negative selection	8943686
44231361	44231384	21	-	27260156	SU8686	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.5745217091915948	[335]	[499,416,596,475]	8	hSpCas9	negative selection	8943687
44231279	44231302	21	-	27260156	SU8686	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.30099808324648103	[551]	[420,758,667,897]	5	hSpCas9	negative selection	9007943
44238447	44238470	21	-	27260156	SU8686	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.44964683007000616	[201]	[244,227,297,341]	7	hSpCas9	negative selection	9007944
44238451	44238474	21	+	27260156	SU8686	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.15028821434204032	[99]	[92,109,64,83]	-3	hSpCas9	negative selection	9007945
44235447	44235470	21	+	27260156	SKES1	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.07647930704285566	[659]	[962,685,560,607]	1	hSpCas9	negative selection	9064936
44235357	44235380	21	-	27260156	SKES1	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.1314700802533223	[361]	[429,404,204,302]	-3	hSpCas9	negative selection	9064937
44231361	44231384	21	-	27260156	SKES1	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.525174584577279	[335]	[663,329,522,420]	9	hSpCas9	negative selection	9064938
44231279	44231302	21	-	27260156	SKES1	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	-0.12565357229250712	[551]	[416,464,544,561]	-3	hSpCas9	negative selection	9129194
44238447	44238470	21	-	27260156	SKES1	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.2053832869276062	[201]	[269,243,238,185]	4	hSpCas9	negative selection	9129195
44238451	44238474	21	+	27260156	SKES1	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.15871798106846668	[99]	[57,128,69,98]	-3	hSpCas9	negative selection	9129196
44235447	44235470	21	+	27260156	TOV112D	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	0.02082463964418757	[659]	[670,1184,569,389]	0	hSpCas9	negative selection	9186187
44235357	44235380	21	-	27260156	TOV112D	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	0.4999243734696247	[361]	[294,690,375,707]	8	hSpCas9	negative selection	9186188
44231361	44231384	21	-	27260156	TOV112D	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.642384982016642	[335]	[645,713,421,378]	9	hSpCas9	negative selection	9186189
44231279	44231302	21	-	27260156	TOV112D	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.09877081556517159	[551]	[600,760,437,608]	2	hSpCas9	negative selection	9250445
44238447	44238470	21	-	27260156	TOV112D	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.308741280735516	[201]	[249,233,269,243]	6	hSpCas9	negative selection	9250446
44238451	44238474	21	+	27260156	TOV112D	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	0.10045625395388447	[99]	[75,168,130,66]	2	hSpCas9	negative selection	9250447
44235447	44235470	21	+	27260156	TC71	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.002564305113044729	[659]	[664,827,621,713]	0	hSpCas9	negative selection	9307438
44235357	44235380	21	-	27260156	TC71	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.2031815290798108	[361]	[302,408,282,356]	-5	hSpCas9	negative selection	9307439
44231361	44231384	21	-	27260156	TC71	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.25973049747436405	[335]	[407,381,521,408]	6	hSpCas9	negative selection	9307440
44231279	44231302	21	-	27260156	TC71	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.09006326854483698	[551]	[629,486,605,807]	2	hSpCas9	negative selection	9371696
44238447	44238470	21	-	27260156	TC71	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.4876976944460434	[201]	[383,252,229,350]	9	hSpCas9	negative selection	9371697
44238451	44238474	21	+	27260156	TC71	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.3453821291040873	[99]	[114,71,69,79]	-7	hSpCas9	negative selection	9371698
44235447	44235470	21	+	27260156	TC32	viability	CTTATTGATCCAGTACACGTTGG	ICOSLG	ENSG00000160223	-0.005363867284126245	[659]	[501,468,900,687]	0	hSpCas9	negative selection	9428689
44235357	44235380	21	-	27260156	TC32	viability	ATGACGTGGTCAGCGTGCTGAGG	ICOSLG	ENSG00000160223	-0.5777931553049724	[361]	[241,188,327,164]	-8	hSpCas9	negative selection	9428690
44231361	44231384	21	-	27260156	TC32	viability	CGCGGCCACGTGGAGCATCCTGG	ICOSLG	ENSG00000160223	0.6377441141716255	[335]	[418,431,681,464]	9	hSpCas9	negative selection	9428691
44231279	44231302	21	-	27260156	TC32	viability	TGCCTCCAACACAGCTATGCAGG	ICOSLG	ENSG00000160223	0.12515629918762472	[551]	[677,254,870,584]	2	hSpCas9	negative selection	9492947
44238447	44238470	21	-	27260156	TC32	viability	CTCTTCAGCAGCCTTCGAGCTGG	ICOSLG	ENSG00000160223	0.47811273523234077	[201]	[231,242,311,274]	7	hSpCas9	negative selection	9492948
44238451	44238474	21	+	27260156	TC32	viability	CTCGAAGGCTGCTGAAGAGCAGG	ICOSLG	ENSG00000160223	-0.06617936201739028	[99]	[73,80,111,95]	-1	hSpCas9	negative selection	9492949
44229021	44229044	21	+	27869803	HPAFII	viability after 27 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.41983745611644285	[872]	[577,643,NaN]	3	hSpCas9	negative selection	9579497
5034583	5034606	21	-	27869803	HPAFII	viability after 27 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.41983745611644285	[872]	[577,643,NaN]	3	hSpCas9	negative selection	9579498
44229834	44229857	21	+	27869803	HPAFII	viability after 27 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-2.8722756027663454	[156]	[7,13,NaN]	-9	hSpCas9	negative selection	9579499
5033641	5033664	21	-	27869803	HPAFII	viability after 27 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-2.8722756027663454	[156]	[7,13,NaN]	-9	hSpCas9	negative selection	9579500
44231317	44231340	21	-	27869803	HPAFII	viability after 27 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	0.7922179575448944	[201]	[148,212,NaN]	6	hSpCas9	negative selection	9579501
5032158	5032181	21	+	27869803	HPAFII	viability after 27 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	0.7922179575448944	[201]	[148,212,NaN]	6	hSpCas9	negative selection	9579502
44235453	44235476	21	+	27869803	HPAFII	viability after 27 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.5838145858830444	[105]	[52,23,NaN]	-4	hSpCas9	negative selection	9579503
5028022	5028045	21	-	27869803	HPAFII	viability after 27 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.5838145858830444	[105]	[52,23,NaN]	-4	hSpCas9	negative selection	9579504
44236960	44236983	21	+	27869803	HPAFII	viability after 27 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.13884121048544637	[195]	[89,132,NaN]	1	hSpCas9	negative selection	9579505
5026515	5026538	21	-	27869803	HPAFII	viability after 27 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.13884121048544637	[195]	[89,132,NaN]	1	hSpCas9	negative selection	9579506
44237004	44237027	21	-	27869803	HPAFII	viability after 27 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.8250015778623632	[301]	[415,168,NaN]	6	hSpCas9	negative selection	9579507
5026471	5026494	21	+	27869803	HPAFII	viability after 27 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.8250015778623632	[301]	[415,168,NaN]	6	hSpCas9	negative selection	9579508
44229021	44229044	21	+	27869803	HPAFII	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.11514097500301079	[872]	[1075,978,NaN]	1	hSpCas9	negative selection	9661946
5034583	5034606	21	-	27869803	HPAFII	viability after 15 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.11514097500301079	[872]	[1075,978,NaN]	1	hSpCas9	negative selection	9661947
44229834	44229857	21	+	27869803	HPAFII	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-0.08159797847636208	[156]	[201,132,NaN]	-1	hSpCas9	negative selection	9661948
5033641	5033664	21	-	27869803	HPAFII	viability after 15 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-0.08159797847636208	[156]	[201,132,NaN]	-1	hSpCas9	negative selection	9661949
44231317	44231340	21	-	27869803	HPAFII	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	0.2813391372491745	[201]	[343,213,NaN]	3	hSpCas9	negative selection	9661950
5032158	5032181	21	+	27869803	HPAFII	viability after 15 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	0.2813391372491745	[201]	[343,213,NaN]	3	hSpCas9	negative selection	9661951
44235453	44235476	21	+	27869803	HPAFII	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.6275482631215066	[105]	[127,39,NaN]	-6	hSpCas9	negative selection	9661952
5028022	5028045	21	-	27869803	HPAFII	viability after 15 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.6275482631215066	[105]	[127,39,NaN]	-6	hSpCas9	negative selection	9661953
44236960	44236983	21	+	27869803	HPAFII	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.21906658854313796	[195]	[304,207,NaN]	2	hSpCas9	negative selection	9661954
5026515	5026538	21	-	27869803	HPAFII	viability after 15 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.21906658854313796	[195]	[304,207,NaN]	2	hSpCas9	negative selection	9661955
44237004	44237027	21	-	27869803	HPAFII	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.12087815702814264	[301]	[540,235,NaN]	1	hSpCas9	negative selection	9661956
5026471	5026494	21	+	27869803	HPAFII	viability after 15 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.12087815702814264	[301]	[540,235,NaN]	1	hSpCas9	negative selection	9661957
44229021	44229044	21	+	27869803	ASPC1	viability after 36 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.0037768889297178365	[1924]	[662,387,900]	0	hSpCas9	negative selection	9744395
5034583	5034606	21	-	27869803	ASPC1	viability after 36 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.0037768889297178365	[1924]	[662,387,900]	0	hSpCas9	negative selection	9744396
44229834	44229857	21	+	27869803	ASPC1	viability after 36 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.03895857141501491	[297]	[50,34,201]	0	hSpCas9	negative selection	9744397
5033641	5033664	21	-	27869803	ASPC1	viability after 36 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.03895857141501491	[297]	[50,34,201]	0	hSpCas9	negative selection	9744398
44231317	44231340	21	-	27869803	ASPC1	viability after 36 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.08048034996305142	[540]	[77,343,115]	-1	hSpCas9	negative selection	9744399
5032158	5032181	21	+	27869803	ASPC1	viability after 36 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.08048034996305142	[540]	[77,343,115]	-1	hSpCas9	negative selection	9744400
44235453	44235476	21	+	27869803	ASPC1	viability after 36 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-1.4708541717280963	[318]	[98,36,0]	-8	hSpCas9	negative selection	9744401
5028022	5028045	21	-	27869803	ASPC1	viability after 36 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-1.4708541717280963	[318]	[98,36,0]	-8	hSpCas9	negative selection	9744402
44236960	44236983	21	+	27869803	ASPC1	viability after 36 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.2592100539072611	[432]	[123,142,248]	2	hSpCas9	negative selection	9744403
5026515	5026538	21	-	27869803	ASPC1	viability after 36 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.2592100539072611	[432]	[123,142,248]	2	hSpCas9	negative selection	9744404
44237004	44237027	21	-	27869803	ASPC1	viability after 36 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.7282360017560532	[732]	[613,627,123]	7	hSpCas9	negative selection	9744405
5026471	5026494	21	+	27869803	ASPC1	viability after 36 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.7282360017560532	[732]	[613,627,123]	7	hSpCas9	negative selection	9744406
44229021	44229044	21	+	27869803	PATU8988S	viability after 35 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.5559382081324473	[1726]	[1041,1002,NaN]	6	hSpCas9	negative selection	9826844
5034583	5034606	21	-	27869803	PATU8988S	viability after 35 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.5559382081324473	[1726]	[1041,1002,NaN]	6	hSpCas9	negative selection	9826845
44229834	44229857	21	+	27869803	PATU8988S	viability after 35 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.1234375082262229	[187]	[73,90,NaN]	1	hSpCas9	negative selection	9826846
5033641	5033664	21	-	27869803	PATU8988S	viability after 35 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.1234375082262229	[187]	[73,90,NaN]	1	hSpCas9	negative selection	9826847
44231317	44231340	21	-	27869803	PATU8988S	viability after 35 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	-0.0869676324467007	[430]	[132,193,NaN]	-1	hSpCas9	negative selection	9826848
5032158	5032181	21	+	27869803	PATU8988S	viability after 35 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	-0.0869676324467007	[430]	[132,193,NaN]	-1	hSpCas9	negative selection	9826849
44235453	44235476	21	+	27869803	PATU8988S	viability after 35 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-1.1962167805242776	[246]	[5,80,NaN]	-8	hSpCas9	negative selection	9826850
5028022	5028045	21	-	27869803	PATU8988S	viability after 35 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-1.1962167805242776	[246]	[5,80,NaN]	-8	hSpCas9	negative selection	9826851
44236960	44236983	21	+	27869803	PATU8988S	viability after 35 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	1.0428247008829068	[401]	[362,303,NaN]	9	hSpCas9	negative selection	9826852
5026515	5026538	21	-	27869803	PATU8988S	viability after 35 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	1.0428247008829068	[401]	[362,303,NaN]	9	hSpCas9	negative selection	9826853
44237004	44237027	21	-	27869803	PATU8988S	viability after 35 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.3601563555969839	[834]	[281,581,NaN]	4	hSpCas9	negative selection	9826854
5026471	5026494	21	+	27869803	PATU8988S	viability after 35 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.3601563555969839	[834]	[281,581,NaN]	4	hSpCas9	negative selection	9826855
44229021	44229044	21	+	27869803	PATU8988S	viability after 31 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.6237347605883097	[1726]	[1068,1050,NaN]	7	hSpCas9	negative selection	9909293
5034583	5034606	21	-	27869803	PATU8988S	viability after 31 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.6237347605883097	[1726]	[1068,1050,NaN]	7	hSpCas9	negative selection	9909294
44229834	44229857	21	+	27869803	PATU8988S	viability after 31 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	0.3214469339583286	[187]	[61,133,NaN]	4	hSpCas9	negative selection	9909295
5033641	5033664	21	-	27869803	PATU8988S	viability after 31 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	0.3214469339583286	[187]	[61,133,NaN]	4	hSpCas9	negative selection	9909296
44231317	44231340	21	-	27869803	PATU8988S	viability after 31 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	0.16971742349937383	[430]	[158,236,NaN]	2	hSpCas9	negative selection	9909297
5032158	5032181	21	+	27869803	PATU8988S	viability after 31 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	0.16971742349937383	[430]	[158,236,NaN]	2	hSpCas9	negative selection	9909298
44235453	44235476	21	+	27869803	PATU8988S	viability after 31 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-1.1416525064526184	[246]	[41,47,NaN]	-8	hSpCas9	negative selection	9909299
5028022	5028045	21	-	27869803	PATU8988S	viability after 31 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-1.1416525064526184	[246]	[41,47,NaN]	-8	hSpCas9	negative selection	9909300
44236960	44236983	21	+	27869803	PATU8988S	viability after 31 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.7035345619288951	[401]	[253,269,NaN]	7	hSpCas9	negative selection	9909301
5026515	5026538	21	-	27869803	PATU8988S	viability after 31 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.7035345619288951	[401]	[253,269,NaN]	7	hSpCas9	negative selection	9909302
44237004	44237027	21	-	27869803	PATU8988S	viability after 31 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.28806303406747524	[834]	[274,573,NaN]	3	hSpCas9	negative selection	9909303
5026471	5026494	21	+	27869803	PATU8988S	viability after 31 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.28806303406747524	[834]	[274,573,NaN]	3	hSpCas9	negative selection	9909304
44229021	44229044	21	+	27869803	HPAFII	viability after 35 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.685571438707578	[872]	[683,740,NaN]	4	hSpCas9	negative selection	9991742
5034583	5034606	21	-	27869803	HPAFII	viability after 35 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.685571438707578	[872]	[683,740,NaN]	4	hSpCas9	negative selection	9991743
44229834	44229857	21	+	27869803	HPAFII	viability after 35 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-6.312532195894953	[156]	[0,0,NaN]	-9	hSpCas9	negative selection	9991744
5033641	5033664	21	-	27869803	HPAFII	viability after 35 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-6.312532195894953	[156]	[0,0,NaN]	-9	hSpCas9	negative selection	9991745
44231317	44231340	21	-	27869803	HPAFII	viability after 35 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	1.6838262424721826	[201]	[122,559,NaN]	9	hSpCas9	negative selection	9991746
5032158	5032181	21	+	27869803	HPAFII	viability after 35 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	1.6838262424721826	[201]	[122,559,NaN]	9	hSpCas9	negative selection	9991747
44235453	44235476	21	+	27869803	HPAFII	viability after 35 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-1.3448512436529814	[105]	[38,0,NaN]	-6	hSpCas9	negative selection	9991748
5028022	5028045	21	-	27869803	HPAFII	viability after 35 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-1.3448512436529814	[105]	[38,0,NaN]	-6	hSpCas9	negative selection	9991749
44236960	44236983	21	+	27869803	HPAFII	viability after 35 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.43236719094508347	[195]	[73,72,NaN]	-3	hSpCas9	negative selection	9991750
5026515	5026538	21	-	27869803	HPAFII	viability after 35 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.43236719094508347	[195]	[73,72,NaN]	-3	hSpCas9	negative selection	9991751
44237004	44237027	21	-	27869803	HPAFII	viability after 35 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.6059107395136589	[301]	[425,14,NaN]	4	hSpCas9	negative selection	9991752
5026471	5026494	21	+	27869803	HPAFII	viability after 35 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.6059107395136589	[301]	[425,14,NaN]	4	hSpCas9	negative selection	9991753
44229021	44229044	21	+	27869803	HPAFII	viability after 31 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000160223	0.153853750829557	[872]	[423,676,NaN]	1	hSpCas9	negative selection	10074191
5034583	5034606	21	-	27869803	HPAFII	viability after 31 days	CGGTGAGCTCCGGTCAAACGTGG	ICOSLG	ENSG00000277117	0.153853750829557	[872]	[423,676,NaN]	1	hSpCas9	negative selection	10074192
44229834	44229857	21	+	27869803	HPAFII	viability after 31 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000160223	-4.89704560866201	[156]	[1,3,NaN]	-9	hSpCas9	negative selection	10074193
5033641	5033664	21	-	27869803	HPAFII	viability after 31 days	AGTGTGACAAAGTGCACACCAGG	ICOSLG	ENSG00000277117	-4.89704560866201	[156]	[1,3,NaN]	-9	hSpCas9	negative selection	10074194
44231317	44231340	21	-	27869803	HPAFII	viability after 31 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000160223	1.3346346544574603	[201]	[138,445,NaN]	8	hSpCas9	negative selection	10074195
5032158	5032181	21	+	27869803	HPAFII	viability after 31 days	TCGTGGCGGTGGCCATAGGCTGG	ICOSLG	ENSG00000277117	1.3346346544574603	[201]	[138,445,NaN]	8	hSpCas9	negative selection	10074196
44235453	44235476	21	+	27869803	HPAFII	viability after 31 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000160223	-0.9463489149734008	[105]	[27,33,NaN]	-5	hSpCas9	negative selection	10074197
5028022	5028045	21	-	27869803	HPAFII	viability after 31 days	GATCCAGTACACGTTGGGCCTGG	ICOSLG	ENSG00000277117	-0.9463489149734008	[105]	[27,33,NaN]	-5	hSpCas9	negative selection	10074198
44236960	44236983	21	+	27869803	HPAFII	viability after 31 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.041606245832825905	[195]	[103,109,NaN]	0	hSpCas9	negative selection	10074199
5026515	5026538	21	-	27869803	HPAFII	viability after 31 days	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.041606245832825905	[195]	[103,109,NaN]	0	hSpCas9	negative selection	10074200
44237004	44237027	21	-	27869803	HPAFII	viability after 31 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000160223	0.39466438400769444	[301]	[307,129,NaN]	3	hSpCas9	negative selection	10074201
5026471	5026494	21	+	27869803	HPAFII	viability after 31 days	CGAGCCCTGATGTCACCGGCCGG	ICOSLG	ENSG00000277117	0.39466438400769444	[301]	[307,129,NaN]	3	hSpCas9	negative selection	10074202
5026287	5026310	21	+	28162770	P31FUJ	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-1.3583330864982375	[71]	[32]	-7	hSpCas9	negative selection	10172446
44237188	44237211	21	-	28162770	P31FUJ	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-1.3583330864982375	[71]	[32]	-7	hSpCas9	negative selection	10172447
5032144	5032167	21	+	28162770	P31FUJ	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.04658019550689896	[116]	[141]	0	hSpCas9	negative selection	10172448
44231331	44231354	21	-	28162770	P31FUJ	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.04658019550689896	[116]	[141]	0	hSpCas9	negative selection	10172449
44236960	44236983	21	+	28162770	P31FUJ	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-1.022584497024033	[101]	[58]	-6	hSpCas9	negative selection	10172450
5026515	5026538	21	-	28162770	P31FUJ	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-1.022584497024033	[101]	[58]	-6	hSpCas9	negative selection	10172451
44235321	44235344	21	+	28162770	P31FUJ	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.39227050968093025	[200]	[309]	4	hSpCas9	negative selection	10172452
5028154	5028177	21	-	28162770	P31FUJ	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.39227050968093025	[200]	[309]	4	hSpCas9	negative selection	10172453
5026389	5026412	21	+	28162770	P31FUJ	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.33051530226679776	[290]	[429]	3	hSpCas9	negative selection	10172454
44237086	44237109	21	-	28162770	P31FUJ	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.33051530226679776	[290]	[429]	3	hSpCas9	negative selection	10172455
44235502	44235525	21	+	28162770	P31FUJ	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	0.6530267756663102	[45]	[84]	7	hSpCas9	negative selection	10172456
5027973	5027996	21	-	28162770	P31FUJ	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	0.6530267756663102	[45]	[84]	7	hSpCas9	negative selection	10172457
44235428	44235451	21	-	28162770	P31FUJ	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	1.2725930389884592	[204]	[581]	9	hSpCas9	negative selection	10172458
5028047	5028070	21	+	28162770	P31FUJ	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	1.2725930389884592	[204]	[581]	9	hSpCas9	negative selection	10172459
5028104	5028127	21	+	28162770	P31FUJ	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.1949463466140191	[564]	[759]	2	hSpCas9	negative selection	10172460
44235371	44235394	21	-	28162770	P31FUJ	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.1949463466140191	[564]	[759]	2	hSpCas9	negative selection	10172461
44236985	44237008	21	+	28162770	P31FUJ	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	-0.45836190482950967	[151]	[129]	-4	hSpCas9	negative selection	10172462
5026490	5026513	21	-	28162770	P31FUJ	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	-0.45836190482950967	[151]	[129]	-4	hSpCas9	negative selection	10172463
5026575	5026598	21	+	28162770	P31FUJ	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.04896876400100092	[203]	[247]	0	hSpCas9	negative selection	10172464
44236900	44236923	21	-	28162770	P31FUJ	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.04896876400100092	[203]	[247]	0	hSpCas9	negative selection	10172465
5026287	5026310	21	+	28162770	TF1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10341812
44237188	44237211	21	-	28162770	TF1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10341813
5032144	5032167	21	+	28162770	TF1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10341814
44231331	44231354	21	-	28162770	TF1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[30]	1	hSpCas9	negative selection	10341815
44236960	44236983	21	+	28162770	TF1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10341816
5026515	5026538	21	-	28162770	TF1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[79]	1	hSpCas9	negative selection	10341817
44235321	44235344	21	+	28162770	TF1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10341818
5028154	5028177	21	-	28162770	TF1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10341819
5026389	5026412	21	+	28162770	TF1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10341820
44237086	44237109	21	-	28162770	TF1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[230]	1	hSpCas9	negative selection	10341821
44235502	44235525	21	+	28162770	TF1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10341822
5027973	5027996	21	-	28162770	TF1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[37]	1	hSpCas9	negative selection	10341823
44235428	44235451	21	-	28162770	TF1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[408]	1	hSpCas9	negative selection	10341824
5028047	5028070	21	+	28162770	TF1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[408]	1	hSpCas9	negative selection	10341825
5028104	5028127	21	+	28162770	TF1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[463]	1	hSpCas9	negative selection	10341826
44235371	44235394	21	-	28162770	TF1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[463]	1	hSpCas9	negative selection	10341827
44236985	44237008	21	+	28162770	TF1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10341828
5026490	5026513	21	-	28162770	TF1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10341829
5026575	5026598	21	+	28162770	TF1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10341830
44236900	44236923	21	-	28162770	TF1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	NaN	[NaN]	[196]	1	hSpCas9	negative selection	10341831
5026287	5026310	21	+	28162770	SKM1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-3.1439297929093675	[19]	[3]	-9	hSpCas9	negative selection	10511178
44237188	44237211	21	-	28162770	SKM1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-3.1439297929093675	[19]	[3]	-9	hSpCas9	negative selection	10511179
5032144	5032167	21	+	28162770	SKM1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.43579605944564137	[22]	[54]	4	hSpCas9	negative selection	10511180
44231331	44231354	21	-	28162770	SKM1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.43579605944564137	[22]	[54]	4	hSpCas9	negative selection	10511181
44236960	44236983	21	+	28162770	SKM1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.4999263968653569	[13]	[34]	5	hSpCas9	negative selection	10511182
5026515	5026538	21	-	28162770	SKM1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.4999263968653569	[13]	[34]	5	hSpCas9	negative selection	10511183
44235321	44235344	21	+	28162770	SKM1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.6656636013442357	[45]	[128]	6	hSpCas9	negative selection	10511184
5028154	5028177	21	-	28162770	SKM1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.6656636013442357	[45]	[128]	6	hSpCas9	negative selection	10511185
5026389	5026412	21	+	28162770	SKM1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.1129032737561097	[67]	[129]	1	hSpCas9	negative selection	10511186
44237086	44237109	21	-	28162770	SKM1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.1129032737561097	[67]	[129]	1	hSpCas9	negative selection	10511187
44235502	44235525	21	+	28162770	SKM1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	-0.0850361038557994	[17]	[29]	0	hSpCas9	negative selection	10511188
5027973	5027996	21	-	28162770	SKM1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	-0.0850361038557994	[17]	[29]	0	hSpCas9	negative selection	10511189
44235428	44235451	21	-	28162770	SKM1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	1.3479233034203069	[47]	[215]	9	hSpCas9	negative selection	10511190
5028047	5028070	21	+	28162770	SKM1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	1.3479233034203069	[47]	[215]	9	hSpCas9	negative selection	10511191
5028104	5028127	21	+	28162770	SKM1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-1.1189834357791368	[128]	[104]	-7	hSpCas9	negative selection	10511192
44235371	44235394	21	-	28162770	SKM1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-1.1189834357791368	[128]	[104]	-7	hSpCas9	negative selection	10511193
44236985	44237008	21	+	28162770	SKM1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	1.076118687958781	[32]	[122]	8	hSpCas9	negative selection	10511194
5026490	5026513	21	-	28162770	SKM1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	1.076118687958781	[32]	[122]	8	hSpCas9	negative selection	10511195
5026575	5026598	21	+	28162770	SKM1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	1.039801008057975	[51]	[188]	8	hSpCas9	negative selection	10511196
44236900	44236923	21	-	28162770	SKM1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	1.039801008057975	[51]	[188]	8	hSpCas9	negative selection	10511197
5026287	5026310	21	+	28162770	SKM1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-3.1439297929093675	[19]	[3]	-9	hSpCas9	negative selection	10680544
44237188	44237211	21	-	28162770	SKM1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-3.1439297929093675	[19]	[3]	-9	hSpCas9	negative selection	10680545
5032144	5032167	21	+	28162770	SKM1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.43579605944564137	[22]	[54]	4	hSpCas9	negative selection	10680546
44231331	44231354	21	-	28162770	SKM1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.43579605944564137	[22]	[54]	4	hSpCas9	negative selection	10680547
44236960	44236983	21	+	28162770	SKM1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.4999263968653569	[13]	[34]	5	hSpCas9	negative selection	10680548
5026515	5026538	21	-	28162770	SKM1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.4999263968653569	[13]	[34]	5	hSpCas9	negative selection	10680549
44235321	44235344	21	+	28162770	SKM1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.6656636013442357	[45]	[128]	6	hSpCas9	negative selection	10680550
5028154	5028177	21	-	28162770	SKM1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.6656636013442357	[45]	[128]	6	hSpCas9	negative selection	10680551
5026389	5026412	21	+	28162770	SKM1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.1129032737561097	[67]	[129]	1	hSpCas9	negative selection	10680552
44237086	44237109	21	-	28162770	SKM1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.1129032737561097	[67]	[129]	1	hSpCas9	negative selection	10680553
44235502	44235525	21	+	28162770	SKM1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	-0.0850361038557994	[17]	[29]	0	hSpCas9	negative selection	10680554
5027973	5027996	21	-	28162770	SKM1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	-0.0850361038557994	[17]	[29]	0	hSpCas9	negative selection	10680555
44235428	44235451	21	-	28162770	SKM1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	1.3479233034203069	[47]	[215]	9	hSpCas9	negative selection	10680556
5028047	5028070	21	+	28162770	SKM1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	1.3479233034203069	[47]	[215]	9	hSpCas9	negative selection	10680557
5028104	5028127	21	+	28162770	SKM1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-1.1189834357791368	[128]	[104]	-7	hSpCas9	negative selection	10680558
44235371	44235394	21	-	28162770	SKM1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-1.1189834357791368	[128]	[104]	-7	hSpCas9	negative selection	10680559
44236985	44237008	21	+	28162770	SKM1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	1.076118687958781	[32]	[122]	8	hSpCas9	negative selection	10680560
5026490	5026513	21	-	28162770	SKM1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	1.076118687958781	[32]	[122]	8	hSpCas9	negative selection	10680561
5026575	5026598	21	+	28162770	SKM1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	1.039801008057975	[51]	[188]	8	hSpCas9	negative selection	10680562
44236900	44236923	21	-	28162770	SKM1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	1.039801008057975	[51]	[188]	8	hSpCas9	negative selection	10680563
5026287	5026310	21	+	28162770	PL21	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-1.4187702181551733	[42]	[6]	-7	hSpCas9	negative selection	10849910
44237188	44237211	21	-	28162770	PL21	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-1.4187702181551733	[42]	[6]	-7	hSpCas9	negative selection	10849911
5032144	5032167	21	+	28162770	PL21	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.8089488571648442	[79]	[60]	7	hSpCas9	negative selection	10849912
44231331	44231354	21	-	28162770	PL21	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.8089488571648442	[79]	[60]	7	hSpCas9	negative selection	10849913
44236960	44236983	21	+	28162770	PL21	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.3521427079343704	[62]	[34]	3	hSpCas9	negative selection	10849914
5026515	5026538	21	-	28162770	PL21	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.3521427079343704	[62]	[34]	3	hSpCas9	negative selection	10849915
44235321	44235344	21	+	28162770	PL21	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	1.6983904820171458	[159]	[225]	9	hSpCas9	negative selection	10849916
5028154	5028177	21	-	28162770	PL21	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	1.6983904820171458	[159]	[225]	9	hSpCas9	negative selection	10849917
5026389	5026412	21	+	28162770	PL21	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	-0.38482288623183586	[248]	[82]	-3	hSpCas9	negative selection	10849918
44237086	44237109	21	-	28162770	PL21	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	-0.38482288623183586	[248]	[82]	-3	hSpCas9	negative selection	10849919
44235502	44235525	21	+	28162770	PL21	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	0.030214613047007788	[53]	[23]	0	hSpCas9	negative selection	10849920
5027973	5027996	21	-	28162770	PL21	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	0.030214613047007788	[53]	[23]	0	hSpCas9	negative selection	10849921
44235428	44235451	21	-	28162770	PL21	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.17887099773566878	[204]	[100]	1	hSpCas9	negative selection	10849922
5028047	5028070	21	+	28162770	PL21	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.17887099773566878	[204]	[100]	1	hSpCas9	negative selection	10849923
5028104	5028127	21	+	28162770	PL21	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	1.1886133611082927	[376]	[373]	8	hSpCas9	negative selection	10849924
44235371	44235394	21	-	28162770	PL21	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	1.1886133611082927	[376]	[373]	8	hSpCas9	negative selection	10849925
44236985	44237008	21	+	28162770	PL21	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	1.9923347293759184	[81]	[141]	9	hSpCas9	negative selection	10849926
5026490	5026513	21	-	28162770	PL21	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	1.9923347293759184	[81]	[141]	9	hSpCas9	negative selection	10849927
5026575	5026598	21	+	28162770	PL21	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	1.401397822736424	[166]	[191]	9	hSpCas9	negative selection	10849928
44236900	44236923	21	-	28162770	PL21	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	1.401397822736424	[166]	[191]	9	hSpCas9	negative selection	10849929
5026287	5026310	21	+	28162770	P31FUJ	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-1.3583330864982375	[71]	[32]	-7	hSpCas9	negative selection	11019276
44237188	44237211	21	-	28162770	P31FUJ	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-1.3583330864982375	[71]	[32]	-7	hSpCas9	negative selection	11019277
5032144	5032167	21	+	28162770	P31FUJ	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.04658019550689896	[116]	[141]	0	hSpCas9	negative selection	11019278
44231331	44231354	21	-	28162770	P31FUJ	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.04658019550689896	[116]	[141]	0	hSpCas9	negative selection	11019279
44236960	44236983	21	+	28162770	P31FUJ	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-1.022584497024033	[101]	[58]	-6	hSpCas9	negative selection	11019280
5026515	5026538	21	-	28162770	P31FUJ	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-1.022584497024033	[101]	[58]	-6	hSpCas9	negative selection	11019281
44235321	44235344	21	+	28162770	P31FUJ	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.39227050968093025	[200]	[309]	4	hSpCas9	negative selection	11019282
5028154	5028177	21	-	28162770	P31FUJ	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.39227050968093025	[200]	[309]	4	hSpCas9	negative selection	11019283
5026389	5026412	21	+	28162770	P31FUJ	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.33051530226679776	[290]	[429]	3	hSpCas9	negative selection	11019284
44237086	44237109	21	-	28162770	P31FUJ	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.33051530226679776	[290]	[429]	3	hSpCas9	negative selection	11019285
44235502	44235525	21	+	28162770	P31FUJ	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	0.6530267756663102	[45]	[84]	7	hSpCas9	negative selection	11019286
5027973	5027996	21	-	28162770	P31FUJ	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	0.6530267756663102	[45]	[84]	7	hSpCas9	negative selection	11019287
44235428	44235451	21	-	28162770	P31FUJ	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	1.2725930389884592	[204]	[581]	9	hSpCas9	negative selection	11019288
5028047	5028070	21	+	28162770	P31FUJ	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	1.2725930389884592	[204]	[581]	9	hSpCas9	negative selection	11019289
5028104	5028127	21	+	28162770	P31FUJ	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.1949463466140191	[564]	[759]	2	hSpCas9	negative selection	11019290
44235371	44235394	21	-	28162770	P31FUJ	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.1949463466140191	[564]	[759]	2	hSpCas9	negative selection	11019291
44236985	44237008	21	+	28162770	P31FUJ	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	-0.45836190482950967	[151]	[129]	-4	hSpCas9	negative selection	11019292
5026490	5026513	21	-	28162770	P31FUJ	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	-0.45836190482950967	[151]	[129]	-4	hSpCas9	negative selection	11019293
5026575	5026598	21	+	28162770	P31FUJ	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.04896876400100092	[203]	[247]	0	hSpCas9	negative selection	11019294
44236900	44236923	21	-	28162770	P31FUJ	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.04896876400100092	[203]	[247]	0	hSpCas9	negative selection	11019295
5026287	5026310	21	+	28162770	OCIAML5	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-4.173994665751359	[39]	[3]	-9	hSpCas9	negative selection	11188642
44237188	44237211	21	-	28162770	OCIAML5	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-4.173994665751359	[39]	[3]	-9	hSpCas9	negative selection	11188643
5032144	5032167	21	+	28162770	OCIAML5	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	1.368131637059539	[46]	[218]	9	hSpCas9	negative selection	11188644
44231331	44231354	21	-	28162770	OCIAML5	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	1.368131637059539	[46]	[218]	9	hSpCas9	negative selection	11188645
44236960	44236983	21	+	28162770	OCIAML5	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	1.2288534245195706	[51]	[219]	9	hSpCas9	negative selection	11188646
5026515	5026538	21	-	28162770	OCIAML5	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	1.2288534245195706	[51]	[219]	9	hSpCas9	negative selection	11188647
44235321	44235344	21	+	28162770	OCIAML5	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.8572240648593609	[99]	[326]	7	hSpCas9	negative selection	11188648
5028154	5028177	21	-	28162770	OCIAML5	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.8572240648593609	[99]	[326]	7	hSpCas9	negative selection	11188649
5026389	5026412	21	+	28162770	OCIAML5	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	-0.2282150567492458	[121]	[187]	-2	hSpCas9	negative selection	11188650
44237086	44237109	21	-	28162770	OCIAML5	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	-0.2282150567492458	[121]	[187]	-2	hSpCas9	negative selection	11188651
44235502	44235525	21	+	28162770	OCIAML5	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	1.0786707666988893	[15]	[60]	8	hSpCas9	negative selection	11188652
5027973	5027996	21	-	28162770	OCIAML5	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	1.0786707666988893	[15]	[60]	8	hSpCas9	negative selection	11188653
44235428	44235451	21	-	28162770	OCIAML5	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.7763538855409351	[108]	[336]	6	hSpCas9	negative selection	11188654
5028047	5028070	21	+	28162770	OCIAML5	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.7763538855409351	[108]	[336]	6	hSpCas9	negative selection	11188655
5028104	5028127	21	+	28162770	OCIAML5	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.1214071346258152	[246]	[484]	1	hSpCas9	negative selection	11188656
44235371	44235394	21	-	28162770	OCIAML5	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.1214071346258152	[246]	[484]	1	hSpCas9	negative selection	11188657
44236985	44237008	21	+	28162770	OCIAML5	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	-0.044711648806392834	[107]	[188]	0	hSpCas9	negative selection	11188658
5026490	5026513	21	-	28162770	OCIAML5	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	-0.044711648806392834	[107]	[188]	0	hSpCas9	negative selection	11188659
5026575	5026598	21	+	28162770	OCIAML5	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	-0.3884103663649744	[123]	[170]	-3	hSpCas9	negative selection	11188660
44236900	44236923	21	-	28162770	OCIAML5	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	-0.3884103663649744	[123]	[170]	-3	hSpCas9	negative selection	11188661
5026287	5026310	21	+	28162770	EOL1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-0.625649310989945	[81]	[27]	-4	hSpCas9	negative selection	11358008
44237188	44237211	21	-	28162770	EOL1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-0.625649310989945	[81]	[27]	-4	hSpCas9	negative selection	11358009
5032144	5032167	21	+	28162770	EOL1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.24382628804394768	[108]	[67]	2	hSpCas9	negative selection	11358010
44231331	44231354	21	-	28162770	EOL1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.24382628804394768	[108]	[67]	2	hSpCas9	negative selection	11358011
44236960	44236983	21	+	28162770	EOL1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.06617441484145448	[154]	[77]	0	hSpCas9	negative selection	11358012
5026515	5026538	21	-	28162770	EOL1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.06617441484145448	[154]	[77]	0	hSpCas9	negative selection	11358013
44235321	44235344	21	+	28162770	EOL1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	-0.12096688768183422	[321]	[155]	-1	hSpCas9	negative selection	11358014
5028154	5028177	21	-	28162770	EOL1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	-0.12096688768183422	[321]	[155]	-1	hSpCas9	negative selection	11358015
5026389	5026412	21	+	28162770	EOL1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.22803861820122062	[503]	[310]	2	hSpCas9	negative selection	11358016
44237086	44237109	21	-	28162770	EOL1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.22803861820122062	[503]	[310]	2	hSpCas9	negative selection	11358017
44235502	44235525	21	+	28162770	EOL1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	-0.258316285579276	[83]	[36]	-2	hSpCas9	negative selection	11358018
5027973	5027996	21	-	28162770	EOL1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	-0.258316285579276	[83]	[36]	-2	hSpCas9	negative selection	11358019
44235428	44235451	21	-	28162770	EOL1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.22773930387631108	[247]	[152]	2	hSpCas9	negative selection	11358020
5028047	5028070	21	+	28162770	EOL1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.22773930387631108	[247]	[152]	2	hSpCas9	negative selection	11358021
5028104	5028127	21	+	28162770	EOL1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.9882532662757526	[442]	[462]	8	hSpCas9	negative selection	11358022
44235371	44235394	21	-	28162770	EOL1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.9882532662757526	[442]	[462]	8	hSpCas9	negative selection	11358023
44236985	44237008	21	+	28162770	EOL1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	0.9633670204610625	[109]	[112]	8	hSpCas9	negative selection	11358024
5026490	5026513	21	-	28162770	EOL1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	0.9633670204610625	[109]	[112]	8	hSpCas9	negative selection	11358025
5026575	5026598	21	+	28162770	EOL1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.8159065115667105	[192]	[178]	7	hSpCas9	negative selection	11358026
44236900	44236923	21	-	28162770	EOL1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.8159065115667105	[192]	[178]	7	hSpCas9	negative selection	11358027
5026287	5026310	21	+	28162770	MOLM13	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-2.702035619897733	[53]	[5]	-8	hSpCas9	negative selection	11527374
44237188	44237211	21	-	28162770	MOLM13	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-2.702035619897733	[53]	[5]	-8	hSpCas9	negative selection	11527375
5032144	5032167	21	+	28162770	MOLM13	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	-0.8594725993934116	[132]	[52]	-5	hSpCas9	negative selection	11527376
44231331	44231354	21	-	28162770	MOLM13	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	-0.8594725993934116	[132]	[52]	-5	hSpCas9	negative selection	11527377
44236960	44236983	21	+	28162770	MOLM13	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.013450488102419667	[140]	[100]	0	hSpCas9	negative selection	11527378
5026515	5026538	21	-	28162770	MOLM13	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.013450488102419667	[140]	[100]	0	hSpCas9	negative selection	11527379
44235321	44235344	21	+	28162770	MOLM13	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	1.5544523194238815	[282]	[600]	9	hSpCas9	negative selection	11527380
5028154	5028177	21	-	28162770	MOLM13	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	1.5544523194238815	[282]	[600]	9	hSpCas9	negative selection	11527381
5026389	5026412	21	+	28162770	MOLM13	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.3018794301056498	[321]	[286]	2	hSpCas9	negative selection	11527382
44237086	44237109	21	-	28162770	MOLM13	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.3018794301056498	[321]	[286]	2	hSpCas9	negative selection	11527383
44235502	44235525	21	+	28162770	MOLM13	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	1.216827617376861	[71]	[120]	8	hSpCas9	negative selection	11527384
5027973	5027996	21	-	28162770	MOLM13	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	1.216827617376861	[71]	[120]	8	hSpCas9	negative selection	11527385
44235428	44235451	21	-	28162770	MOLM13	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.184582580684524	[257]	[211]	1	hSpCas9	negative selection	11527386
5028047	5028070	21	+	28162770	MOLM13	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.184582580684524	[257]	[211]	1	hSpCas9	negative selection	11527387
5028104	5028127	21	+	28162770	MOLM13	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	1.115526611195428	[502]	[787]	8	hSpCas9	negative selection	11527388
44235371	44235394	21	-	28162770	MOLM13	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	1.115526611195428	[502]	[787]	8	hSpCas9	negative selection	11527389
44236985	44237008	21	+	28162770	MOLM13	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	0.19597682436433217	[162]	[134]	1	hSpCas9	negative selection	11527390
5026490	5026513	21	-	28162770	MOLM13	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	0.19597682436433217	[162]	[134]	1	hSpCas9	negative selection	11527391
5026575	5026598	21	+	28162770	MOLM13	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	-0.10019930061218112	[254]	[171]	0	hSpCas9	negative selection	11527392
44236900	44236923	21	-	28162770	MOLM13	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	-0.10019930061218112	[254]	[171]	0	hSpCas9	negative selection	11527393
5026287	5026310	21	+	28162770	HEL	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-1.1180735041202168	[60]	[17]	-6	hSpCas9	negative selection	11696740
44237188	44237211	21	-	28162770	HEL	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-1.1180735041202168	[60]	[17]	-6	hSpCas9	negative selection	11696741
5032144	5032167	21	+	28162770	HEL	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	-0.22547129544410205	[114]	[62]	-2	hSpCas9	negative selection	11696742
44231331	44231354	21	-	28162770	HEL	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	-0.22547129544410205	[114]	[62]	-2	hSpCas9	negative selection	11696743
44236960	44236983	21	+	28162770	HEL	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.49073573855530706	[99]	[89]	4	hSpCas9	negative selection	11696744
5026515	5026538	21	-	28162770	HEL	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.49073573855530706	[99]	[89]	4	hSpCas9	negative selection	11696745
44235321	44235344	21	+	28162770	HEL	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.5253818813621981	[255]	[235]	4	hSpCas9	negative selection	11696746
5028154	5028177	21	-	28162770	HEL	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.5253818813621981	[255]	[235]	4	hSpCas9	negative selection	11696747
5026389	5026412	21	+	28162770	HEL	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	-0.4666723847202251	[355]	[164]	-3	hSpCas9	negative selection	11696748
44237086	44237109	21	-	28162770	HEL	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	-0.4666723847202251	[355]	[164]	-3	hSpCas9	negative selection	11696749
44235502	44235525	21	+	28162770	HEL	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	-0.5875587874214372	[60]	[25]	-4	hSpCas9	negative selection	11696750
5027973	5027996	21	-	28162770	HEL	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	-0.5875587874214372	[60]	[25]	-4	hSpCas9	negative selection	11696751
44235428	44235451	21	-	28162770	HEL	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.5260939131480864	[205]	[189]	4	hSpCas9	negative selection	11696752
5028047	5028070	21	+	28162770	HEL	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.5260939131480864	[205]	[189]	4	hSpCas9	negative selection	11696753
5028104	5028127	21	+	28162770	HEL	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.8892747887718403	[427]	[147]	-5	hSpCas9	negative selection	11696754
44235371	44235394	21	-	28162770	HEL	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.8892747887718403	[427]	[147]	-5	hSpCas9	negative selection	11696755
44236985	44237008	21	+	28162770	HEL	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	-0.29992799293369143	[147]	[76]	-2	hSpCas9	negative selection	11696756
5026490	5026513	21	-	28162770	HEL	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	-0.29992799293369143	[147]	[76]	-2	hSpCas9	negative selection	11696757
5026575	5026598	21	+	28162770	HEL	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	-0.5667145336285929	[221]	[95]	-4	hSpCas9	negative selection	11696758
44236900	44236923	21	-	28162770	HEL	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	-0.5667145336285929	[221]	[95]	-4	hSpCas9	negative selection	11696759
5026287	5026310	21	+	28162770	MV411	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-3.288615349457434	[57]	[4]	-9	hSpCas9	negative selection	11866106
44237188	44237211	21	-	28162770	MV411	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-3.288615349457434	[57]	[4]	-9	hSpCas9	negative selection	11866107
5032144	5032167	21	+	28162770	MV411	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	-1.0155968550510186	[107]	[44]	-6	hSpCas9	negative selection	11866108
44231331	44231354	21	-	28162770	MV411	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	-1.0155968550510186	[107]	[44]	-6	hSpCas9	negative selection	11866109
44236960	44236983	21	+	28162770	MV411	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-0.6370852317972886	[95]	[51]	-4	hSpCas9	negative selection	11866110
5026515	5026538	21	-	28162770	MV411	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-0.6370852317972886	[95]	[51]	-4	hSpCas9	negative selection	11866111
44235321	44235344	21	+	28162770	MV411	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.9844031449489815	[149]	[249]	8	hSpCas9	negative selection	11866112
5028154	5028177	21	-	28162770	MV411	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.9844031449489815	[149]	[249]	8	hSpCas9	negative selection	11866113
5026389	5026412	21	+	28162770	MV411	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	-0.21553442555977043	[305]	[221]	-2	hSpCas9	negative selection	11866114
44237086	44237109	21	-	28162770	MV411	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	-0.21553442555977043	[305]	[221]	-2	hSpCas9	negative selection	11866115
44235502	44235525	21	+	28162770	MV411	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	0.025045129446327863	[41]	[35]	0	hSpCas9	negative selection	11866116
5027973	5027996	21	-	28162770	MV411	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	0.025045129446327863	[41]	[35]	0	hSpCas9	negative selection	11866117
44235428	44235451	21	-	28162770	MV411	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.6055726588271421	[180]	[231]	5	hSpCas9	negative selection	11866118
5028047	5028070	21	+	28162770	MV411	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.6055726588271421	[180]	[231]	5	hSpCas9	negative selection	11866119
5028104	5028127	21	+	28162770	MV411	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.23317685765760576	[304]	[301]	2	hSpCas9	negative selection	11866120
44235371	44235394	21	-	28162770	MV411	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.23317685765760576	[304]	[301]	2	hSpCas9	negative selection	11866121
44236985	44237008	21	+	28162770	MV411	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	1.428503109830288	[85]	[194]	9	hSpCas9	negative selection	11866122
5026490	5026513	21	-	28162770	MV411	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	1.428503109830288	[85]	[194]	9	hSpCas9	negative selection	11866123
5026575	5026598	21	+	28162770	MV411	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.2046879033234382	[136]	[132]	1	hSpCas9	negative selection	11866124
44236900	44236923	21	-	28162770	MV411	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.2046879033234382	[136]	[132]	1	hSpCas9	negative selection	11866125
5026287	5026310	21	+	28162770	MONOMAC1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-0.27720719574353736	[36]	[34]	-2	hSpCas9	negative selection	12035472
44237188	44237211	21	-	28162770	MONOMAC1	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-0.27720719574353736	[36]	[34]	-2	hSpCas9	negative selection	12035473
5032144	5032167	21	+	28162770	MONOMAC1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	-0.06210726697344504	[50]	[55]	0	hSpCas9	negative selection	12035474
44231331	44231354	21	-	28162770	MONOMAC1	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	-0.06210726697344504	[50]	[55]	0	hSpCas9	negative selection	12035475
44236960	44236983	21	+	28162770	MONOMAC1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	-1.6418216897324494	[48]	[17]	-8	hSpCas9	negative selection	12035476
5026515	5026538	21	-	28162770	MONOMAC1	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	-1.6418216897324494	[48]	[17]	-8	hSpCas9	negative selection	12035477
44235321	44235344	21	+	28162770	MONOMAC1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.3062871846372451	[102]	[145]	3	hSpCas9	negative selection	12035478
5028154	5028177	21	-	28162770	MONOMAC1	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.3062871846372451	[102]	[145]	3	hSpCas9	negative selection	12035479
5026389	5026412	21	+	28162770	MONOMAC1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.43198083373953794	[171]	[265]	4	hSpCas9	negative selection	12035480
44237086	44237109	21	-	28162770	MONOMAC1	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.43198083373953794	[171]	[265]	4	hSpCas9	negative selection	12035481
44235502	44235525	21	+	28162770	MONOMAC1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	1.5352673697367898	[30]	[102]	9	hSpCas9	negative selection	12035482
5027973	5027996	21	-	28162770	MONOMAC1	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	1.5352673697367898	[30]	[102]	9	hSpCas9	negative selection	12035483
44235428	44235451	21	-	28162770	MONOMAC1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.23790020965699493	[107]	[145]	2	hSpCas9	negative selection	12035484
5028047	5028070	21	+	28162770	MONOMAC1	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.23790020965699493	[107]	[145]	2	hSpCas9	negative selection	12035485
5028104	5028127	21	+	28162770	MONOMAC1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.897476565200646	[246]	[151]	-6	hSpCas9	negative selection	12035486
44235371	44235394	21	-	28162770	MONOMAC1	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.897476565200646	[246]	[151]	-6	hSpCas9	negative selection	12035487
44236985	44237008	21	+	28162770	MONOMAC1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	0.3879256536616025	[61]	[92]	4	hSpCas9	negative selection	12035488
5026490	5026513	21	-	28162770	MONOMAC1	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	0.3879256536616025	[61]	[92]	4	hSpCas9	negative selection	12035489
5026575	5026598	21	+	28162770	MONOMAC1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	-0.21280416291787013	[91]	[90]	-2	hSpCas9	negative selection	12035490
44236900	44236923	21	-	28162770	MONOMAC1	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	-0.21280416291787013	[91]	[90]	-2	hSpCas9	negative selection	12035491
5026287	5026310	21	+	28162770	OCIAML2	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	-0.7098174891215872	[17]	[60]	-5	hSpCas9	negative selection	12204838
44237188	44237211	21	-	28162770	OCIAML2	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	-0.7098174891215872	[17]	[60]	-5	hSpCas9	negative selection	12204839
5032144	5032167	21	+	28162770	OCIAML2	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	0.14604153520633334	[14]	[91]	1	hSpCas9	negative selection	12204840
44231331	44231354	21	-	28162770	OCIAML2	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	0.14604153520633334	[14]	[91]	1	hSpCas9	negative selection	12204841
44236960	44236983	21	+	28162770	OCIAML2	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	0.15386103966563236	[17]	[110]	1	hSpCas9	negative selection	12204842
5026515	5026538	21	-	28162770	OCIAML2	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	0.15386103966563236	[17]	[110]	1	hSpCas9	negative selection	12204843
44235321	44235344	21	+	28162770	OCIAML2	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.5790009424824393	[24]	[206]	5	hSpCas9	negative selection	12204844
5028154	5028177	21	-	28162770	OCIAML2	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.5790009424824393	[24]	[206]	5	hSpCas9	negative selection	12204845
5026389	5026412	21	+	28162770	OCIAML2	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.17071514537651372	[45]	[286]	1	hSpCas9	negative selection	12204846
44237086	44237109	21	-	28162770	OCIAML2	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.17071514537651372	[45]	[286]	1	hSpCas9	negative selection	12204847
44235502	44235525	21	+	28162770	OCIAML2	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	-0.1013960155764424	[11]	[61]	-1	hSpCas9	negative selection	12204848
5027973	5027996	21	-	28162770	OCIAML2	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	-0.1013960155764424	[11]	[61]	-1	hSpCas9	negative selection	12204849
44235428	44235451	21	-	28162770	OCIAML2	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.9330923608088484	[23]	[253]	8	hSpCas9	negative selection	12204850
5028047	5028070	21	+	28162770	OCIAML2	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.9330923608088484	[23]	[253]	8	hSpCas9	negative selection	12204851
5028104	5028127	21	+	28162770	OCIAML2	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	0.1857173087157603	[68]	[434]	1	hSpCas9	negative selection	12204852
44235371	44235394	21	-	28162770	OCIAML2	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	0.1857173087157603	[68]	[434]	1	hSpCas9	negative selection	12204853
44236985	44237008	21	+	28162770	OCIAML2	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	0.02762104228566431	[19]	[112]	0	hSpCas9	negative selection	12204854
5026490	5026513	21	-	28162770	OCIAML2	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	0.02762104228566431	[19]	[112]	0	hSpCas9	negative selection	12204855
5026575	5026598	21	+	28162770	OCIAML2	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	-0.2877657680923507	[36]	[167]	-2	hSpCas9	negative selection	12204856
44236900	44236923	21	-	28162770	OCIAML2	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	-0.2877657680923507	[36]	[167]	-2	hSpCas9	negative selection	12204857
5026287	5026310	21	+	28162770	OCIAML3	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000277117	0.6539198731194225	[11]	[56]	6	hSpCas9	negative selection	12374204
44237188	44237211	21	-	28162770	OCIAML3	viability	GGAGAAGGAAGTCAGAGCGATGG	ICOSLG	ENSG00000160223	0.6539198731194225	[11]	[56]	6	hSpCas9	negative selection	12374205
5032144	5032167	21	+	28162770	OCIAML3	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000277117	-1.816400061660611	[27]	[23]	-8	hSpCas9	negative selection	12374206
44231331	44231354	21	-	28162770	OCIAML3	viability	GTGCCTGCTTGTGGTCGTGGCGG	ICOSLG	ENSG00000160223	-1.816400061660611	[27]	[23]	-8	hSpCas9	negative selection	12374207
44236960	44236983	21	+	28162770	OCIAML3	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000160223	1.1873520732004965	[15]	[109]	8	hSpCas9	negative selection	12374208
5026515	5026538	21	-	28162770	OCIAML3	viability	GGGTGACGTTGAACAAGCGCAGG	ICOSLG	ENSG00000277117	1.1873520732004965	[15]	[109]	8	hSpCas9	negative selection	12374209
44235321	44235344	21	+	28162770	OCIAML3	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000160223	0.13590319630809244	[40]	[135]	1	hSpCas9	negative selection	12374210
5028154	5028177	21	-	28162770	OCIAML3	viability	GCAGCAGCCAATGTTCACGCTGG	ICOSLG	ENSG00000277117	0.13590319630809244	[40]	[135]	1	hSpCas9	negative selection	12374211
5026389	5026412	21	+	28162770	OCIAML3	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000277117	0.806663569784478	[81]	[432]	7	hSpCas9	negative selection	12374212
44237086	44237109	21	-	28162770	OCIAML3	viability	AACCAGTGAGTCGAAAACCGTGG	ICOSLG	ENSG00000160223	0.806663569784478	[81]	[432]	7	hSpCas9	negative selection	12374213
44235502	44235525	21	+	28162770	OCIAML3	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000160223	0.8153832958135386	[15]	[84]	7	hSpCas9	negative selection	12374214
5027973	5027996	21	-	28162770	OCIAML3	viability	AAGGTGAGCTCATCCTGGGAGGG	ICOSLG	ENSG00000277117	0.8153832958135386	[15]	[84]	7	hSpCas9	negative selection	12374215
44235428	44235451	21	-	28162770	OCIAML3	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000160223	0.7582030214992421	[65]	[336]	6	hSpCas9	negative selection	12374216
5028047	5028070	21	+	28162770	OCIAML3	viability	TAAGACGGACAACAGCCTGCTGG	ICOSLG	ENSG00000277117	0.7582030214992421	[65]	[336]	6	hSpCas9	negative selection	12374217
5028104	5028127	21	+	28162770	OCIAML3	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000277117	-0.04926223967940846	[96]	[282]	0	hSpCas9	negative selection	12374218
44235371	44235394	21	-	28162770	OCIAML3	viability	CATGCGGGGCTTGTATGACGTGG	ICOSLG	ENSG00000160223	-0.04926223967940846	[96]	[282]	0	hSpCas9	negative selection	12374219
44236985	44237008	21	+	28162770	OCIAML3	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000160223	-0.6346496248215089	[35]	[69]	-5	hSpCas9	negative selection	12374220
5026490	5026513	21	-	28162770	OCIAML3	viability	GAAGTCGCCCCGCAGCATGCCGG	ICOSLG	ENSG00000277117	-0.6346496248215089	[35]	[69]	-5	hSpCas9	negative selection	12374221
5026575	5026598	21	+	28162770	OCIAML3	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000277117	0.7788016235653833	[38]	[201]	7	hSpCas9	negative selection	12374222
44236900	44236923	21	-	28162770	OCIAML3	viability	CCAATCCCTGGGATTCCAGGAGG	ICOSLG	ENSG00000160223	0.7788016235653833	[38]	[201]	7	hSpCas9	negative selection	12374223