Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3551
• Symbol:IKBKB
• Description:inhibitor of nuclear factor kappa B kinase subunit beta

DataSource: http://genomecrispr.dkfz.de/#!/results/IKBKB

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
42290162	42290185	8	-	26472758	Jiyoye	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-0.9851420412728871	[20]	[7]	-6	hSpCas9	negative selection	77075
42316790	42316813	8	+	26472758	Jiyoye	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.5771003829481856	[175]	[197]	4	hSpCas9	negative selection	77076
42308999	42309022	8	-	26472758	Jiyoye	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	1.5893787127266226	[51]	[117]	8	hSpCas9	negative selection	77077
42314331	42314354	8	+	26472758	Jiyoye	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.27478344569092383	[222]	[138]	-2	hSpCas9	negative selection	77078
42316805	42316828	8	+	26472758	Jiyoye	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-5.8966053666712295	[78]	[0]	-9	hSpCas9	negative selection	77079
42319610	42319633	8	+	26472758	Jiyoye	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.744068198870364	[210]	[94]	-5	hSpCas9	negative selection	77080
42326055	42326078	8	-	26472758	Jiyoye	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	0.20786657328246683	[61]	[53]	1	hSpCas9	negative selection	77081
42290178	42290201	8	+	26472758	Jiyoye	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.15924786806228775	[398]	[335]	1	hSpCas9	negative selection	77082
42293449	42293472	8	+	26472758	Jiyoye	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	1.3588123599444744	[90]	[175]	7	hSpCas9	negative selection	77083
42305187	42305210	8	-	26472758	Jiyoye	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.8099227401610614	[271]	[116]	-5	hSpCas9	negative selection	77084
42290162	42290185	8	-	26472758	KBM7	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.2324133951139637	[162,169]	[41,25]	-7	hSpCas9	negative selection	268193
42316790	42316813	8	+	26472758	KBM7	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.6636119924220379	[816,687]	[656,469]	7	hSpCas9	negative selection	268194
42308999	42309022	8	-	26472758	KBM7	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-0.4730981534157306	[380,290]	[106,117]	-4	hSpCas9	negative selection	268195
42314331	42314354	8	+	26472758	KBM7	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.8094071684057308	[511,429]	[137,114]	-6	hSpCas9	negative selection	268196
42316805	42316828	8	+	26472758	KBM7	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-0.9945339399156383	[104,79]	[37,6]	-6	hSpCas9	negative selection	268197
42319610	42319633	8	+	26472758	KBM7	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-1.7314610747411567	[963,797]	[92,151]	-8	hSpCas9	negative selection	268198
42326055	42326078	8	-	26472758	KBM7	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	-0.3314119928723409	[327,223]	[145,61]	-3	hSpCas9	negative selection	268199
42290178	42290201	8	+	26472758	KBM7	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	-0.013966359321856192	[1788,1635]	[784,808]	0	hSpCas9	negative selection	268200
42293449	42293472	8	+	26472758	KBM7	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.30720167450667824	[652,640]	[417,341]	3	hSpCas9	negative selection	268201
42305187	42305210	8	-	26472758	KBM7	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.8569656928828625	[346,402]	[363,286]	8	hSpCas9	negative selection	268202
42290162	42290185	8	-	26472758	Raji	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-2.8622428155828823	[93]	[2]	-9	hSpCas9	negative selection	459311
42316790	42316813	8	+	26472758	Raji	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	-1.7255064787911423	[455]	[31]	-8	hSpCas9	negative selection	459312
42308999	42309022	8	-	26472758	Raji	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-2.140543978069986	[189]	[9]	-8	hSpCas9	negative selection	459313
42314331	42314354	8	+	26472758	Raji	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-4.102069830255351	[221]	[2]	-9	hSpCas9	negative selection	459314
42316805	42316828	8	+	26472758	Raji	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	0.10738353537359924	[3]	[0]	1	hSpCas9	negative selection	459315
42319610	42319633	8	+	26472758	Raji	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-3.226517201179839	[362]	[8]	-9	hSpCas9	negative selection	459316
42326055	42326078	8	-	26472758	Raji	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	-0.7699339448515721	[168]	[22]	-5	hSpCas9	negative selection	459317
42290178	42290201	8	+	26472758	Raji	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	-2.3619928447352017	[1018]	[45]	-9	hSpCas9	negative selection	459318
42293449	42293472	8	+	26472758	Raji	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	-3.9694320616772316	[404]	[5]	-9	hSpCas9	negative selection	459319
42305187	42305210	8	-	26472758	Raji	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-2.559373056511204	[253]	[9]	-9	hSpCas9	negative selection	459320
42290162	42290185	8	-	26472758	K562	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-6.777949085362007	[129]	[0]	-9	hSpCas9	negative selection	650429
42316790	42316813	8	+	26472758	K562	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.9310653685170942	[670]	[1079]	7	hSpCas9	negative selection	650430
42308999	42309022	8	-	26472758	K562	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-1.4205970246207444	[351]	[110]	-6	hSpCas9	negative selection	650431
42314331	42314354	8	+	26472758	K562	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.589160511236619	[457]	[256]	-4	hSpCas9	negative selection	650432
42316805	42316828	8	+	26472758	K562	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-6.164972208471254	[84]	[0]	-9	hSpCas9	negative selection	650433
42319610	42319633	8	+	26472758	K562	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-1.49103539958216	[635]	[190]	-6	hSpCas9	negative selection	650434
42326055	42326078	8	-	26472758	K562	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	1.1871614100572465	[256]	[493]	8	hSpCas9	negative selection	650435
42290178	42290201	8	+	26472758	K562	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.4727900014923163	[1375]	[1611]	4	hSpCas9	negative selection	650436
42293449	42293472	8	+	26472758	K562	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.24965537603259402	[549]	[551]	2	hSpCas9	negative selection	650437
42305187	42305210	8	-	26472758	K562	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.03175947839618028	[418]	[345]	0	hSpCas9	negative selection	650438
42271452	42271475	8	-	26627737	DLD1	viability	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.3986106100883553	[777]	[453,328,197]	4	hSpCas9	negative selection	839602
42272152	42272175	8	+	26627737	DLD1	viability	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.793281517921904	[249]	[150,173,89]	7	hSpCas9	negative selection	839603
42288681	42288704	8	-	26627737	DLD1	viability	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.0648675601864559	[211]	[52,70,65]	0	hSpCas9	negative selection	839604
42290252	42290275	8	+	26627737	DLD1	viability	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.3322819960122977	[442]	[161,206,157]	3	hSpCas9	negative selection	839605
42293461	42293484	8	+	26627737	DLD1	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.3071288040824625	[379]	[267,76,99]	3	hSpCas9	negative selection	839606
42305253	42305276	8	+	26627737	DLD1	viability	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.6920964680058082	[1039]	[201,190,208]	-6	hSpCas9	negative selection	839607
42271452	42271475	8	-	26627737	GBM cells	viability after 5 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.03230129016338845	[350]	[212,171]	0	hSpCas9	negative selection	921917
42272152	42272175	8	+	26627737	GBM cells	viability after 5 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.4629739178743938	[301]	[147,86]	-6	hSpCas9	negative selection	921918
42288681	42288704	8	-	26627737	GBM cells	viability after 5 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	0.739435660878489	[85]	[97,55]	8	hSpCas9	negative selection	921919
42290252	42290275	8	+	26627737	GBM cells	viability after 5 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.2083972034064029	[162]	[78,122]	3	hSpCas9	negative selection	921920
42293461	42293484	8	+	26627737	GBM cells	viability after 5 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.4802560599281451	[132]	[88,109]	7	hSpCas9	negative selection	921921
42305253	42305276	8	+	26627737	GBM cells	viability after 5 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.3049584584799644	[515]	[235,211]	-5	hSpCas9	negative selection	921922
42271452	42271475	8	-	26627737	GBM cells	viability after 13 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.17408036342895927	[350]	[226,204]	2	hSpCas9	negative selection	1004232
42272152	42272175	8	+	26627737	GBM cells	viability after 13 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.23149607576096703	[301]	[170,113]	-3	hSpCas9	negative selection	1004233
42288681	42288704	8	-	26627737	GBM cells	viability after 13 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.043612619158902355	[85]	[36,51]	0	hSpCas9	negative selection	1004234
42290252	42290275	8	+	26627737	GBM cells	viability after 13 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.26059472205559975	[162]	[68,135]	3	hSpCas9	negative selection	1004235
42293461	42293484	8	+	26627737	GBM cells	viability after 13 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.5606335745908797	[132]	[149,70]	7	hSpCas9	negative selection	1004236
42305253	42305276	8	+	26627737	GBM cells	viability after 13 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.23684919197629428	[515]	[300,185]	-3	hSpCas9	negative selection	1004237
42271452	42271475	8	-	26627737	GBM cells	viability after 21 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.27293737199760537	[350]	[161,153]	-3	hSpCas9	negative selection	1086547
42272152	42272175	8	+	26627737	GBM cells	viability after 21 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.3939268510748937	[301]	[127,121]	-4	hSpCas9	negative selection	1086548
42288681	42288704	8	-	26627737	GBM cells	viability after 21 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-1.3976396151937684	[85]	[23,11]	-8	hSpCas9	negative selection	1086549
42290252	42290275	8	+	26627737	GBM cells	viability after 21 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.4483798295657217	[162]	[112,127]	4	hSpCas9	negative selection	1086550
42293461	42293484	8	+	26627737	GBM cells	viability after 21 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.752004499042694	[132]	[128,114]	7	hSpCas9	negative selection	1086551
42305253	42305276	8	+	26627737	GBM cells	viability after 21 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.15575101823152315	[515]	[259,243]	-1	hSpCas9	negative selection	1086552
42271452	42271475	8	-	26627737	RPE1	viability after 9 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.37889333575832024	[1288]	[353,253]	-3	hSpCas9	negative selection	1168862
42272152	42272175	8	+	26627737	RPE1	viability after 9 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-1.0885168948861328	[1095]	[149,175]	-7	hSpCas9	negative selection	1168863
42288681	42288704	8	-	26627737	RPE1	viability after 9 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.40977396141169053	[454]	[94,122]	-3	hSpCas9	negative selection	1168864
42290252	42290275	8	+	26627737	RPE1	viability after 9 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.42605457036871003	[943]	[493,271]	3	hSpCas9	negative selection	1168865
42293461	42293484	8	+	26627737	RPE1	viability after 9 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.915040193054739	[334]	[264,110]	6	hSpCas9	negative selection	1168866
42305253	42305276	8	+	26627737	RPE1	viability after 9 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.8023136124024014	[1215]	[607,735]	5	hSpCas9	negative selection	1168867
42271452	42271475	8	-	26627737	RPE1	viability after 12 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.17128147799306226	[1288]	[376,233]	-1	hSpCas9	negative selection	1251177
42272152	42272175	8	+	26627737	RPE1	viability after 12 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.46334582425952564	[1095]	[232,192]	-3	hSpCas9	negative selection	1251178
42288681	42288704	8	-	26627737	RPE1	viability after 12 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.9118778014656393	[454]	[97,29]	-6	hSpCas9	negative selection	1251179
42290252	42290275	8	+	26627737	RPE1	viability after 12 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.45510834290031027	[943]	[404,286]	3	hSpCas9	negative selection	1251180
42293461	42293484	8	+	26627737	RPE1	viability after 12 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.33917511826087055	[334]	[108,118]	2	hSpCas9	negative selection	1251181
42305253	42305276	8	+	26627737	RPE1	viability after 12 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.5962173271656125	[1215]	[506,479]	4	hSpCas9	negative selection	1251182
42271452	42271475	8	-	26627737	RPE1	viability after 15 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-1.1958454036331057	[1288]	[261,59]	-6	hSpCas9	negative selection	1333492
42272152	42272175	8	+	26627737	RPE1	viability after 15 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-1.0274755388324661	[1095]	[174,129]	-6	hSpCas9	negative selection	1333493
42288681	42288704	8	-	26627737	RPE1	viability after 15 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-3.3992716394237377	[454]	[0,22]	-9	hSpCas9	negative selection	1333494
42290252	42290275	8	+	26627737	RPE1	viability after 15 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.15386758562757924	[943]	[294,186]	-1	hSpCas9	negative selection	1333495
42293461	42293484	8	+	26627737	RPE1	viability after 15 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	1.0424505328538105	[334]	[268,123]	6	hSpCas9	negative selection	1333496
42305253	42305276	8	+	26627737	RPE1	viability after 15 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	1.0930128559044023	[1215]	[858,612]	6	hSpCas9	negative selection	1333497
42271452	42271475	8	-	26627737	RPE1	viability after 18 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.4963004818136332	[1288]	[409,71]	-3	hSpCas9	negative selection	1415807
42272152	42272175	8	+	26627737	RPE1	viability after 18 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.1166589759624338	[1095]	[164,387]	0	hSpCas9	negative selection	1415808
42288681	42288704	8	-	26627737	RPE1	viability after 18 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-1.7536996253738768	[454]	[62,7]	-8	hSpCas9	negative selection	1415809
42290252	42290275	8	+	26627737	RPE1	viability after 18 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.33615731125572007	[943]	[411,224]	2	hSpCas9	negative selection	1415810
42293461	42293484	8	+	26627737	RPE1	viability after 18 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.42930257246359094	[334]	[84,160]	2	hSpCas9	negative selection	1415811
42305253	42305276	8	+	26627737	RPE1	viability after 18 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.5643427623937948	[1215]	[550,414]	3	hSpCas9	negative selection	1415812
42271452	42271475	8	-	26627737	HeLa	viability after 8 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	1.0563227994813236	[476]	[833,243,313]	7	hSpCas9	negative selection	1498122
42272152	42272175	8	+	26627737	HeLa	viability after 8 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.17452497719759696	[254]	[136,111,128]	1	hSpCas9	negative selection	1498123
42288681	42288704	8	-	26627737	HeLa	viability after 8 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	2.2540205268296756	[32]	[21,100,71]	9	hSpCas9	negative selection	1498124
42290252	42290275	8	+	26627737	HeLa	viability after 8 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.5283761077823951	[358]	[126,107,94]	-5	hSpCas9	negative selection	1498125
42293461	42293484	8	+	26627737	HeLa	viability after 8 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.08067437308438774	[155]	[63,97,52]	0	hSpCas9	negative selection	1498126
42305253	42305276	8	+	26627737	HeLa	viability after 8 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.3193321079995236	[807]	[347,275,238]	-3	hSpCas9	negative selection	1498127
42271452	42271475	8	-	26627737	HeLa	viability after 12 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.7519838572001407	[476]	[532,263,211]	6	hSpCas9	negative selection	1580437
42272152	42272175	8	+	26627737	HeLa	viability after 12 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.4884265238459228	[254]	[73,96,51]	-4	hSpCas9	negative selection	1580438
42288681	42288704	8	-	26627737	HeLa	viability after 12 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	3.014595360363471	[32]	[21,91,215]	9	hSpCas9	negative selection	1580439
42290252	42290275	8	+	26627737	HeLa	viability after 12 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.6992504332854595	[358]	[161,26,93]	-6	hSpCas9	negative selection	1580440
42293461	42293484	8	+	26627737	HeLa	viability after 12 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.9549744236379136	[155]	[172,61,147]	7	hSpCas9	negative selection	1580441
42305253	42305276	8	+	26627737	HeLa	viability after 12 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.38944806463587944	[807]	[369,170,235]	-3	hSpCas9	negative selection	1580442
42271452	42271475	8	-	26627737	HeLa	viability after 15 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	1.2429078363154535	[476]	[526,498,342]	8	hSpCas9	negative selection	1662752
42272152	42272175	8	+	26627737	HeLa	viability after 15 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.01622210643772337	[254]	[167,73,61]	0	hSpCas9	negative selection	1662753
42288681	42288704	8	-	26627737	HeLa	viability after 15 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	3.072449952818187	[32]	[56,202,76]	9	hSpCas9	negative selection	1662754
42290252	42290275	8	+	26627737	HeLa	viability after 15 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.8346510883933536	[358]	[22,148,73]	-6	hSpCas9	negative selection	1662755
42293461	42293484	8	+	26627737	HeLa	viability after 15 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.5621459003903264	[155]	[46,139,94]	4	hSpCas9	negative selection	1662756
42305253	42305276	8	+	26627737	HeLa	viability after 15 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.11430931864934601	[807]	[398,283,386]	1	hSpCas9	negative selection	1662757
42271452	42271475	8	-	26627737	HeLa	viability after 18 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	1.2182531440722313	[476]	[336,414,342]	8	hSpCas9	negative selection	1745067
42272152	42272175	8	+	26627737	HeLa	viability after 18 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.16321292666625142	[254]	[95,57,61]	-1	hSpCas9	negative selection	1745068
42288681	42288704	8	-	26627737	HeLa	viability after 18 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	3.137155050215032	[32]	[41,175,76]	9	hSpCas9	negative selection	1745069
42290252	42290275	8	+	26627737	HeLa	viability after 18 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.8196411639407284	[358]	[18,120,73]	-6	hSpCas9	negative selection	1745070
42293461	42293484	8	+	26627737	HeLa	viability after 18 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.6609258749252884	[155]	[33,128,94]	5	hSpCas9	negative selection	1745071
42305253	42305276	8	+	26627737	HeLa	viability after 18 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.1661835921162329	[807]	[289,238,386]	1	hSpCas9	negative selection	1745072
42271452	42271475	8	-	26627737	HCT116	viability after 6 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	1.849583397049736	[1118]	[147,901]	8	hSpCas9	negative selection	1827382
42272152	42272175	8	+	26627737	HCT116	viability after 6 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	1.0805123448568146	[670]	[137,269]	6	hSpCas9	negative selection	1827383
42288681	42288704	8	-	26627737	HCT116	viability after 6 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	1.9476544152562496	[177]	[47,140]	8	hSpCas9	negative selection	1827384
42290252	42290275	8	+	26627737	HCT116	viability after 6 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.39470089337283587	[349]	[52,82]	2	hSpCas9	negative selection	1827385
42293461	42293484	8	+	26627737	HCT116	viability after 6 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-1.6086447470608376	[462]	[19,25]	-7	hSpCas9	negative selection	1827386
42305253	42305276	8	+	26627737	HCT116	viability after 6 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-1.721514300860966	[907]	[70,27]	-7	hSpCas9	negative selection	1827387
42271452	42271475	8	-	26627737	HCT116	viability after 8 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.5995337613028571	[666]	[159,223,340]	-6	hSpCas9	negative selection	1909697
42272152	42272175	8	+	26627737	HCT116	viability after 8 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.8037959371336802	[193]	[274,147,138]	7	hSpCas9	negative selection	1909698
42288681	42288704	8	-	26627737	HCT116	viability after 8 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.649085446913662	[122]	[23,35,68]	-7	hSpCas9	negative selection	1909699
42290252	42290275	8	+	26627737	HCT116	viability after 8 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.10681489226672303	[195]	[148,72,79]	-1	hSpCas9	negative selection	1909700
42293461	42293484	8	+	26627737	HCT116	viability after 8 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.38293120194773045	[135]	[13,124,151]	4	hSpCas9	negative selection	1909701
42305253	42305276	8	+	26627737	HCT116	viability after 8 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.6344586707316591	[385]	[383,235,370]	6	hSpCas9	negative selection	1909702
42271452	42271475	8	-	26627737	HCT116	viability after 9 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.5227379404780665	[1118]	[378,468]	4	hSpCas9	negative selection	1992012
42272152	42272175	8	+	26627737	HCT116	viability after 9 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.08053618754379971	[670]	[231,119]	0	hSpCas9	negative selection	1992013
42288681	42288704	8	-	26627737	HCT116	viability after 9 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	2.022992372866726	[177]	[243,152]	9	hSpCas9	negative selection	1992014
42290252	42290275	8	+	26627737	HCT116	viability after 9 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.11789761191565862	[349]	[106,96]	0	hSpCas9	negative selection	1992015
42293461	42293484	8	+	26627737	HCT116	viability after 9 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.15544010410063763	[462]	[111,157]	1	hSpCas9	negative selection	1992016
42305253	42305276	8	+	26627737	HCT116	viability after 9 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.004002446312725061	[907]	[198,277]	0	hSpCas9	negative selection	1992017
42271452	42271475	8	-	26627737	HCT116	viability after 12 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.5570849714637771	[666]	[152,187,379]	-5	hSpCas9	negative selection	2074327
42272152	42272175	8	+	26627737	HCT116	viability after 12 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.7488869886890492	[193]	[117,60,336]	6	hSpCas9	negative selection	2074328
42288681	42288704	8	-	26627737	HCT116	viability after 12 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	0.5222948979556182	[122]	[72,40,164]	5	hSpCas9	negative selection	2074329
42290252	42290275	8	+	26627737	HCT116	viability after 12 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.4727925074906377	[195]	[54,100,68]	-5	hSpCas9	negative selection	2074330
42293461	42293484	8	+	26627737	HCT116	viability after 12 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.4969264971790953	[135]	[67,163,74]	5	hSpCas9	negative selection	2074331
42305253	42305276	8	+	26627737	HCT116	viability after 12 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.8740797942111245	[385]	[380,388,344]	7	hSpCas9	negative selection	2074332
42271452	42271475	8	-	26627737	HCT116	viability after 15 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.7550148385985366	[666]	[327,202,162]	-6	hSpCas9	negative selection	2156642
42272152	42272175	8	+	26627737	HCT116	viability after 15 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.4912628523842847	[193]	[143,59,262]	4	hSpCas9	negative selection	2156643
42288681	42288704	8	-	26627737	HCT116	viability after 15 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	0.8377485729049119	[122]	[124,77,174]	7	hSpCas9	negative selection	2156644
42290252	42290275	8	+	26627737	HCT116	viability after 15 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.2620610289145745	[195]	[180,131,97]	2	hSpCas9	negative selection	2156645
42293461	42293484	8	+	26627737	HCT116	viability after 15 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.2666922841092735	[135]	[102,86,92]	2	hSpCas9	negative selection	2156646
42305253	42305276	8	+	26627737	HCT116	viability after 15 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.9159008866649261	[385]	[616,248,412]	7	hSpCas9	negative selection	2156647
42271452	42271475	8	-	26627737	HCT116	viability after 18 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.805486702243605	[666]	[187,195,167]	-6	hSpCas9	negative selection	2238957
42272152	42272175	8	+	26627737	HCT116	viability after 18 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.6587937070470314	[193]	[135,34,286]	5	hSpCas9	negative selection	2238958
42288681	42288704	8	-	26627737	HCT116	viability after 18 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.38846520153253694	[122]	[57,16,63]	-4	hSpCas9	negative selection	2238959
42290252	42290275	8	+	26627737	HCT116	viability after 18 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.2758803705652666	[195]	[113,18,106]	-3	hSpCas9	negative selection	2238960
42293461	42293484	8	+	26627737	HCT116	viability after 18 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.10825060503950579	[135]	[17,114,76]	1	hSpCas9	negative selection	2238961
42305253	42305276	8	+	26627737	HCT116	viability after 18 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.8196863300745474	[385]	[342,341,300]	6	hSpCas9	negative selection	2238962
42290166	42290189	8	-	24336569	HL60	viability	TCTCGGGCAGCCACCACATTGGG	IKBKB	ENSG00000104365	-0.6623004023019423	[610]	[816]	-6	hSpCas9	negative selection	2271382
42290177	42290200	8	+	24336569	HL60	viability	GGCTGCCCGAGATGTCCCTGAGG	IKBKB	ENSG00000104365	0.47562371166879186	[539]	[1588]	4	hSpCas9	negative selection	2271383
42290230	42290253	8	-	24336569	HL60	viability	GCAGTACTCCATGGCCAGCAGGG	IKBKB	ENSG00000104365	0.16086022302942382	[1221]	[2890]	1	hSpCas9	negative selection	2271384
42290235	42290258	8	+	24336569	HL60	viability	CTGGCCATGGAGTACTGCCAAGG	IKBKB	ENSG00000104365	-0.1699150408647052	[1277]	[2403]	-1	hSpCas9	negative selection	2271385
42290248	42290271	8	+	24336569	HL60	viability	ACTGCCAAGGAGGAGATCTCCGG	IKBKB	ENSG00000104365	0.9318183195902348	[918]	[3709]	7	hSpCas9	negative selection	2271386
42293445	42293468	8	-	24336569	HL60	viability	AGCAGTTCTCAAACTGGTTCAGG	IKBKB	ENSG00000104365	0.20534220110903512	[947]	[2312]	2	hSpCas9	negative selection	2271387
42293451	42293474	8	-	24336569	HL60	viability	GACCACAGCAGTTCTCAAACTGG	IKBKB	ENSG00000104365	0.7140492087841914	[366]	[1273]	6	hSpCas9	negative selection	2271388
42293456	42293479	8	+	24336569	HL60	viability	TTGAGAACTGCTGTGGTCTGCGG	IKBKB	ENSG00000104365	-0.2988481252794444	[646]	[1112]	-3	hSpCas9	negative selection	2271389
42293461	42293484	8	+	24336569	HL60	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	1.5601989875719122	[157]	[985]	9	hSpCas9	negative selection	2271390
42293486	42293509	8	-	24336569	HL60	viability	GTCACTCAGCAAGGTGAGGATGG	IKBKB	ENSG00000104365	0.3040258565775491	[1522]	[3978]	3	hSpCas9	negative selection	2271391
42290166	42290189	8	-	24336569	KBM7	viability	TCTCGGGCAGCCACCACATTGGG	IKBKB	ENSG00000104365	0.9120909923300311	[331]	[1703]	7	hSpCas9	negative selection	2338559
42290177	42290200	8	+	24336569	KBM7	viability	GGCTGCCCGAGATGTCCCTGAGG	IKBKB	ENSG00000104365	-0.7073103495580385	[697]	[1165]	-5	hSpCas9	negative selection	2338560
42290230	42290253	8	-	24336569	KBM7	viability	GCAGTACTCCATGGCCAGCAGGG	IKBKB	ENSG00000104365	0.33367600793586116	[1003]	[3450]	3	hSpCas9	negative selection	2338561
42290235	42290258	8	+	24336569	KBM7	viability	CTGGCCATGGAGTACTGCCAAGG	IKBKB	ENSG00000104365	0.3082794904650543	[659]	[2228]	3	hSpCas9	negative selection	2338562
42290248	42290271	8	+	24336569	KBM7	viability	ACTGCCAAGGAGGAGATCTCCGG	IKBKB	ENSG00000104365	0.09323472067241956	[917]	[2670]	0	hSpCas9	negative selection	2338563
42293445	42293468	8	-	24336569	KBM7	viability	AGCAGTTCTCAAACTGGTTCAGG	IKBKB	ENSG00000104365	0.5864555052482676	[575]	[2358]	5	hSpCas9	negative selection	2338564
42293451	42293474	8	-	24336569	KBM7	viability	GACCACAGCAGTTCTCAAACTGG	IKBKB	ENSG00000104365	0.9612263490184467	[347]	[1847]	8	hSpCas9	negative selection	2338565
42293456	42293479	8	+	24336569	KBM7	viability	TTGAGAACTGCTGTGGTCTGCGG	IKBKB	ENSG00000104365	0.20251211560297622	[627]	[1970]	2	hSpCas9	negative selection	2338566
42293461	42293484	8	+	24336569	KBM7	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.4442434839856263	[215]	[432]	-4	hSpCas9	negative selection	2338567
42293486	42293509	8	-	24336569	KBM7	viability	GTCACTCAGCAAGGTGAGGATGG	IKBKB	ENSG00000104365	0.007477543792215657	[1230]	[3374]	0	hSpCas9	negative selection	2338568
42330430	42330453	8	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCACTTTGGGAGGCAGAGGCGAG	IKBKB	ENSG00000104365	1.3055372672802243	[104,28]	[48,21]	5	dCas9-VP64	positive selection	2470055
42330430	42330453	8	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCACTTTGGGAGGCAGAGGCGAG	IKBKB	ENSG00000104365	4.207282944889167	[182,227]	[2502,59]	9	dCas9-VP64	positive selection	2565310
42293445	42293468	8	-	27260157	DLD1	viability	AGCAGTTCTCAAACTGGTTCAGG	IKBKB	ENSG00000104365	0.681164952533713	[]	[]	8	hSpCas9	negative selection	2576069
42293461	42293484	8	+	27260157	DLD1	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.294470636851967	[]	[]	-2	hSpCas9	negative selection	2577967
42272143	42272166	8	+	27260157	DLD1	viability	TGGGAAATGAAAGAGCGCCTTGG	IKBKB	ENSG00000104365	0.453265188461603	[]	[]	7	hSpCas9	negative selection	2578135
42272141	42272164	8	-	27260157	DLD1	viability	AAGGCGCTCTTTCATTTCCCAGG	IKBKB	ENSG00000104365	0.452326494947838	[]	[]	7	hSpCas9	negative selection	2579305
42290252	42290275	8	-	27260157	DLD1	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	1.2199144020417	[]	[]	9	hSpCas9	negative selection	2583077
42290235	42290258	8	+	27260157	DLD1	viability	CTGGCCATGGAGTACTGCCAAGG	IKBKB	ENSG00000104365	0.730121680477613	[]	[]	8	hSpCas9	negative selection	2584930
42293451	42293474	8	-	27260157	DLD1	viability	GACCACAGCAGTTCTCAAACTGG	IKBKB	ENSG00000104365	0.197035923763821	[]	[]	3	hSpCas9	negative selection	2604189
42288647	42288670	8	+	27260157	DLD1	viability	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	0.0205432285490834	[]	[]	0	hSpCas9	negative selection	2604268
42272087	42272110	8	+	27260157	DLD1	viability	AGCACGACATCAGTATGAGCTGG	IKBKB	ENSG00000104365	0.824602614590263	[]	[]	9	hSpCas9	negative selection	2604490
42272116	42272139	8	+	27260157	DLD1	viability	TCCCTGACAACGCAGACATGTGG	IKBKB	ENSG00000104365	0.281253937215718	[]	[]	4	hSpCas9	negative selection	2607430
42290248	42290271	8	+	27260157	DLD1	viability	ACTGCCAAGGAGGAGATCTCCGG	IKBKB	ENSG00000104365	0.457805923626182	[]	[]	7	hSpCas9	negative selection	2608511
42293486	42293509	8	-	27260157	DLD1	viability	GTCACTCAGCAAGGTGAGGATGG	IKBKB	ENSG00000104365	0.125151656603661	[]	[]	3	hSpCas9	negative selection	2608580
42271450	42271473	8	-	27260157	DLD1	viability	CACCTGTCGGCAGGGACGCGGGG	IKBKB	ENSG00000104365	0.531892641600782	[]	[]	8	hSpCas9	negative selection	2612913
42290177	42290200	8	+	27260157	DLD1	viability	GGCTGCCCGAGATGTCCCTGAGG	IKBKB	ENSG00000104365	0.111912798824086	[]	[]	3	hSpCas9	negative selection	2616208
42288681	42288704	8	-	27260157	DLD1	viability	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	1.03876695952859	[]	[]	9	hSpCas9	negative selection	2616726
42290230	42290253	8	-	27260157	DLD1	viability	GCAGTACTCCATGGCCAGCAGGG	IKBKB	ENSG00000104365	1.07636803233848	[]	[]	9	hSpCas9	negative selection	2618269
42290166	42290189	8	-	27260157	DLD1	viability	TCTCGGGCAGCCACCACATTGGG	IKBKB	ENSG00000104365	1.01983049536158	[]	[]	9	hSpCas9	negative selection	2622071
42288687	42288710	8	+	27260157	DLD1	viability	GAACCGAGAGCGGTGGTGCCTGG	IKBKB	ENSG00000104365	0.679233452382295	[]	[]	8	hSpCas9	negative selection	2642313
42293456	42293479	8	+	27260157	DLD1	viability	TTGAGAACTGCTGTGGTCTGCGG	IKBKB	ENSG00000104365	-0.250319607404587	[]	[]	-2	hSpCas9	negative selection	2647894
42288653	42288676	8	-	27260157	DLD1	viability	CTCCTGCCGGCACTGCTTGATGG	IKBKB	ENSG00000104365	0.721268993930313	[]	[]	8	hSpCas9	negative selection	2648853
42293445	42293468	8	-	27260157	HT1080	viability	AGCAGTTCTCAAACTGGTTCAGG	IKBKB	ENSG00000104365	0.123984290932998	[]	[]	1	hSpCas9	negative selection	2652199
42293461	42293484	8	+	27260157	HT1080	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.0511681933410952	[]	[]	0	hSpCas9	negative selection	2654097
42272143	42272166	8	+	27260157	HT1080	viability	TGGGAAATGAAAGAGCGCCTTGG	IKBKB	ENSG00000104365	1.27855146608023	[]	[]	9	hSpCas9	negative selection	2654265
42272141	42272164	8	-	27260157	HT1080	viability	AAGGCGCTCTTTCATTTCCCAGG	IKBKB	ENSG00000104365	-0.428728635950437	[]	[]	-7	hSpCas9	negative selection	2655435
42290252	42290275	8	-	27260157	HT1080	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.735299816229232	[]	[]	6	hSpCas9	negative selection	2659207
42290235	42290258	8	+	27260157	HT1080	viability	CTGGCCATGGAGTACTGCCAAGG	IKBKB	ENSG00000104365	-0.822082551736035	[]	[]	-8	hSpCas9	negative selection	2661060
42293451	42293474	8	-	27260157	HT1080	viability	GACCACAGCAGTTCTCAAACTGG	IKBKB	ENSG00000104365	0.918555532326922	[]	[]	7	hSpCas9	negative selection	2680319
42288647	42288670	8	+	27260157	HT1080	viability	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	-0.176495783574985	[]	[]	0	hSpCas9	negative selection	2680398
42272087	42272110	8	+	27260157	HT1080	viability	AGCACGACATCAGTATGAGCTGG	IKBKB	ENSG00000104365	0.581362457779136	[]	[]	5	hSpCas9	negative selection	2680620
42272116	42272139	8	+	27260157	HT1080	viability	TCCCTGACAACGCAGACATGTGG	IKBKB	ENSG00000104365	0.756189451231258	[]	[]	6	hSpCas9	negative selection	2683560
42290248	42290271	8	+	27260157	HT1080	viability	ACTGCCAAGGAGGAGATCTCCGG	IKBKB	ENSG00000104365	0.257555707460985	[]	[]	2	hSpCas9	negative selection	2684641
42293486	42293509	8	-	27260157	HT1080	viability	GTCACTCAGCAAGGTGAGGATGG	IKBKB	ENSG00000104365	0.486870459756827	[]	[]	4	hSpCas9	negative selection	2684710
42271450	42271473	8	-	27260157	HT1080	viability	CACCTGTCGGCAGGGACGCGGGG	IKBKB	ENSG00000104365	1.02422355569203	[]	[]	8	hSpCas9	negative selection	2689043
42290177	42290200	8	+	27260157	HT1080	viability	GGCTGCCCGAGATGTCCCTGAGG	IKBKB	ENSG00000104365	0.34160024468784	[]	[]	3	hSpCas9	negative selection	2692338
42288681	42288704	8	-	27260157	HT1080	viability	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.0531916892123898	[]	[]	0	hSpCas9	negative selection	2692856
42290230	42290253	8	-	27260157	HT1080	viability	GCAGTACTCCATGGCCAGCAGGG	IKBKB	ENSG00000104365	0.730572417382498	[]	[]	6	hSpCas9	negative selection	2694399
42290166	42290189	8	-	27260157	HT1080	viability	TCTCGGGCAGCCACCACATTGGG	IKBKB	ENSG00000104365	0.353222964176653	[]	[]	3	hSpCas9	negative selection	2698201
42288687	42288710	8	+	27260157	HT1080	viability	GAACCGAGAGCGGTGGTGCCTGG	IKBKB	ENSG00000104365	1.5405478402625	[]	[]	9	hSpCas9	negative selection	2718443
42293456	42293479	8	+	27260157	HT1080	viability	TTGAGAACTGCTGTGGTCTGCGG	IKBKB	ENSG00000104365	0.690800831161332	[]	[]	6	hSpCas9	negative selection	2724024
42288653	42288676	8	-	27260157	HT1080	viability	CTCCTGCCGGCACTGCTTGATGG	IKBKB	ENSG00000104365	0.607919080879179	[]	[]	5	hSpCas9	negative selection	2724983
42293445	42293468	8	-	27260157	MKN45	viability	AGCAGTTCTCAAACTGGTTCAGG	IKBKB	ENSG00000104365	0.815622118432205	[]	[]	8	hSpCas9	negative selection	2728329
42293461	42293484	8	+	27260157	MKN45	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.395483064855067	[]	[]	6	hSpCas9	negative selection	2730227
42272143	42272166	8	+	27260157	MKN45	viability	TGGGAAATGAAAGAGCGCCTTGG	IKBKB	ENSG00000104365	0.539432973193573	[]	[]	7	hSpCas9	negative selection	2730395
42272141	42272164	8	-	27260157	MKN45	viability	AAGGCGCTCTTTCATTTCCCAGG	IKBKB	ENSG00000104365	0.410141567912085	[]	[]	6	hSpCas9	negative selection	2731565
42290252	42290275	8	-	27260157	MKN45	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.294978152282497	[]	[]	5	hSpCas9	negative selection	2735337
42290235	42290258	8	+	27260157	MKN45	viability	CTGGCCATGGAGTACTGCCAAGG	IKBKB	ENSG00000104365	-0.0312463926537726	[]	[]	0	hSpCas9	negative selection	2737190
42293451	42293474	8	-	27260157	MKN45	viability	GACCACAGCAGTTCTCAAACTGG	IKBKB	ENSG00000104365	0.586442991791118	[]	[]	7	hSpCas9	negative selection	2756449
42288647	42288670	8	+	27260157	MKN45	viability	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	-0.0802222347663585	[]	[]	0	hSpCas9	negative selection	2756528
42272087	42272110	8	+	27260157	MKN45	viability	AGCACGACATCAGTATGAGCTGG	IKBKB	ENSG00000104365	0.282977151342697	[]	[]	5	hSpCas9	negative selection	2756750
42272116	42272139	8	+	27260157	MKN45	viability	TCCCTGACAACGCAGACATGTGG	IKBKB	ENSG00000104365	0.792952390503189	[]	[]	7	hSpCas9	negative selection	2759690
42290248	42290271	8	+	27260157	MKN45	viability	ACTGCCAAGGAGGAGATCTCCGG	IKBKB	ENSG00000104365	0.126845786323065	[]	[]	4	hSpCas9	negative selection	2760771
42293486	42293509	8	-	27260157	MKN45	viability	GTCACTCAGCAAGGTGAGGATGG	IKBKB	ENSG00000104365	0.118450662411696	[]	[]	4	hSpCas9	negative selection	2760840
42271450	42271473	8	-	27260157	MKN45	viability	CACCTGTCGGCAGGGACGCGGGG	IKBKB	ENSG00000104365	1.16843181681143	[]	[]	8	hSpCas9	negative selection	2765173
42290177	42290200	8	+	27260157	MKN45	viability	GGCTGCCCGAGATGTCCCTGAGG	IKBKB	ENSG00000104365	-0.737810927886683	[]	[]	-7	hSpCas9	negative selection	2768468
42288681	42288704	8	-	27260157	MKN45	viability	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	0.144633717535969	[]	[]	5	hSpCas9	negative selection	2768986
42290230	42290253	8	-	27260157	MKN45	viability	GCAGTACTCCATGGCCAGCAGGG	IKBKB	ENSG00000104365	0.729731198856667	[]	[]	7	hSpCas9	negative selection	2770529
42290166	42290189	8	-	27260157	MKN45	viability	TCTCGGGCAGCCACCACATTGGG	IKBKB	ENSG00000104365	-0.44028871850388	[]	[]	-6	hSpCas9	negative selection	2774331
42288687	42288710	8	+	27260157	MKN45	viability	GAACCGAGAGCGGTGGTGCCTGG	IKBKB	ENSG00000104365	0.887450842089706	[]	[]	8	hSpCas9	negative selection	2794573
42293456	42293479	8	+	27260157	MKN45	viability	TTGAGAACTGCTGTGGTCTGCGG	IKBKB	ENSG00000104365	-0.141044587003654	[]	[]	0	hSpCas9	negative selection	2800154
42288653	42288676	8	-	27260157	MKN45	viability	CTCCTGCCGGCACTGCTTGATGG	IKBKB	ENSG00000104365	1.03321399937914	[]	[]	8	hSpCas9	negative selection	2801113
42293445	42293468	8	-	27260157	RKO	viability	AGCAGTTCTCAAACTGGTTCAGG	IKBKB	ENSG00000104365	0.721473948560939	[]	[]	8	hSpCas9	negative selection	2804459
42293461	42293484	8	+	27260157	RKO	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.416795790065317	[]	[]	2	hSpCas9	negative selection	2806357
42272143	42272166	8	+	27260157	RKO	viability	TGGGAAATGAAAGAGCGCCTTGG	IKBKB	ENSG00000104365	0.955027221124642	[]	[]	8	hSpCas9	negative selection	2806525
42272141	42272164	8	-	27260157	RKO	viability	AAGGCGCTCTTTCATTTCCCAGG	IKBKB	ENSG00000104365	0.115713378182904	[]	[]	0	hSpCas9	negative selection	2807695
42290252	42290275	8	-	27260157	RKO	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	-0.460366896007343	[]	[]	-6	hSpCas9	negative selection	2811467
42290235	42290258	8	+	27260157	RKO	viability	CTGGCCATGGAGTACTGCCAAGG	IKBKB	ENSG00000104365	-0.269133194820301	[]	[]	-1	hSpCas9	negative selection	2813320
42293451	42293474	8	-	27260157	RKO	viability	GACCACAGCAGTTCTCAAACTGG	IKBKB	ENSG00000104365	-0.0885846733715867	[]	[]	0	hSpCas9	negative selection	2832579
42288647	42288670	8	+	27260157	RKO	viability	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	0.276117234878873	[]	[]	1	hSpCas9	negative selection	2832658
42272087	42272110	8	+	27260157	RKO	viability	AGCACGACATCAGTATGAGCTGG	IKBKB	ENSG00000104365	-0.489967009564142	[]	[]	-6	hSpCas9	negative selection	2832880
42272116	42272139	8	+	27260157	RKO	viability	TCCCTGACAACGCAGACATGTGG	IKBKB	ENSG00000104365	-0.479289725495912	[]	[]	-6	hSpCas9	negative selection	2835820
42290248	42290271	8	+	27260157	RKO	viability	ACTGCCAAGGAGGAGATCTCCGG	IKBKB	ENSG00000104365	0.656283710430386	[]	[]	3	hSpCas9	negative selection	2836901
42293486	42293509	8	-	27260157	RKO	viability	GTCACTCAGCAAGGTGAGGATGG	IKBKB	ENSG00000104365	0.360369770131943	[]	[]	2	hSpCas9	negative selection	2836970
42271450	42271473	8	-	27260157	RKO	viability	CACCTGTCGGCAGGGACGCGGGG	IKBKB	ENSG00000104365	0.46539929352546	[]	[]	2	hSpCas9	negative selection	2841303
42290177	42290200	8	+	27260157	RKO	viability	GGCTGCCCGAGATGTCCCTGAGG	IKBKB	ENSG00000104365	1.15340943874597	[]	[]	9	hSpCas9	negative selection	2844598
42288681	42288704	8	-	27260157	RKO	viability	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	0.260034853794985	[]	[]	1	hSpCas9	negative selection	2845116
42290230	42290253	8	-	27260157	RKO	viability	GCAGTACTCCATGGCCAGCAGGG	IKBKB	ENSG00000104365	0.434967820574551	[]	[]	2	hSpCas9	negative selection	2846659
42290166	42290189	8	-	27260157	RKO	viability	TCTCGGGCAGCCACCACATTGGG	IKBKB	ENSG00000104365	-0.126438121622086	[]	[]	0	hSpCas9	negative selection	2850461
42288687	42288710	8	+	27260157	RKO	viability	GAACCGAGAGCGGTGGTGCCTGG	IKBKB	ENSG00000104365	1.29589362066727	[]	[]	9	hSpCas9	negative selection	2870703
42293456	42293479	8	+	27260157	RKO	viability	TTGAGAACTGCTGTGGTCTGCGG	IKBKB	ENSG00000104365	0.61086074792182	[]	[]	3	hSpCas9	negative selection	2876284
42288653	42288676	8	-	27260157	RKO	viability	CTCCTGCCGGCACTGCTTGATGG	IKBKB	ENSG00000104365	1.11741006396171	[]	[]	9	hSpCas9	negative selection	2877243
42293445	42293468	8	-	27260157	SF268	viability	AGCAGTTCTCAAACTGGTTCAGG	IKBKB	ENSG00000104365	-0.0284487445481976	[]	[]	0	hSpCas9	negative selection	2880589
42293461	42293484	8	+	27260157	SF268	viability	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.00779232710283357	[]	[]	0	hSpCas9	negative selection	2882487
42272143	42272166	8	+	27260157	SF268	viability	TGGGAAATGAAAGAGCGCCTTGG	IKBKB	ENSG00000104365	0.579622848706379	[]	[]	8	hSpCas9	negative selection	2882655
42272141	42272164	8	-	27260157	SF268	viability	AAGGCGCTCTTTCATTTCCCAGG	IKBKB	ENSG00000104365	-1.20757930156842	[]	[]	-7	hSpCas9	negative selection	2883825
42290252	42290275	8	-	27260157	SF268	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.811636580460217	[]	[]	8	hSpCas9	negative selection	2887597
42290235	42290258	8	+	27260157	SF268	viability	CTGGCCATGGAGTACTGCCAAGG	IKBKB	ENSG00000104365	0.355313883860159	[]	[]	4	hSpCas9	negative selection	2889450
42293451	42293474	8	-	27260157	SF268	viability	GACCACAGCAGTTCTCAAACTGG	IKBKB	ENSG00000104365	-0.00912604611846835	[]	[]	0	hSpCas9	negative selection	2908709
42288647	42288670	8	+	27260157	SF268	viability	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	0.254588782667285	[]	[]	4	hSpCas9	negative selection	2908788
42272087	42272110	8	+	27260157	SF268	viability	AGCACGACATCAGTATGAGCTGG	IKBKB	ENSG00000104365	0.0584642358179728	[]	[]	0	hSpCas9	negative selection	2909010
42272116	42272139	8	+	27260157	SF268	viability	TCCCTGACAACGCAGACATGTGG	IKBKB	ENSG00000104365	0.15321734207468	[]	[]	0	hSpCas9	negative selection	2911950
42290248	42290271	8	+	27260157	SF268	viability	ACTGCCAAGGAGGAGATCTCCGG	IKBKB	ENSG00000104365	0.410889776109702	[]	[]	4	hSpCas9	negative selection	2913031
42293486	42293509	8	-	27260157	SF268	viability	GTCACTCAGCAAGGTGAGGATGG	IKBKB	ENSG00000104365	1.22823869244383	[]	[]	9	hSpCas9	negative selection	2913100
42271450	42271473	8	-	27260157	SF268	viability	CACCTGTCGGCAGGGACGCGGGG	IKBKB	ENSG00000104365	1.05393440460916	[]	[]	9	hSpCas9	negative selection	2917433
42290177	42290200	8	+	27260157	SF268	viability	GGCTGCCCGAGATGTCCCTGAGG	IKBKB	ENSG00000104365	-0.618234205000018	[]	[]	-5	hSpCas9	negative selection	2920728
42288681	42288704	8	-	27260157	SF268	viability	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	0.699418731614078	[]	[]	8	hSpCas9	negative selection	2921246
42290230	42290253	8	-	27260157	SF268	viability	GCAGTACTCCATGGCCAGCAGGG	IKBKB	ENSG00000104365	0.785679191907405	[]	[]	8	hSpCas9	negative selection	2922789
42290166	42290189	8	-	27260157	SF268	viability	TCTCGGGCAGCCACCACATTGGG	IKBKB	ENSG00000104365	0.585288850476992	[]	[]	8	hSpCas9	negative selection	2926591
42288687	42288710	8	+	27260157	SF268	viability	GAACCGAGAGCGGTGGTGCCTGG	IKBKB	ENSG00000104365	1.43563188585523	[]	[]	9	hSpCas9	negative selection	2946833
42293456	42293479	8	+	27260157	SF268	viability	TTGAGAACTGCTGTGGTCTGCGG	IKBKB	ENSG00000104365	0.0560273024532932	[]	[]	0	hSpCas9	negative selection	2952414
42288653	42288676	8	-	27260157	SF268	viability	CTCCTGCCGGCACTGCTTGATGG	IKBKB	ENSG00000104365	0.971158916962289	[]	[]	9	hSpCas9	negative selection	2953373
42305187	42305210	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.5632136637088914	[2,2]	[1,0]	-7	hSpCas9	positive selection	2995144
42317722	42317745	8	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATGAGACTCAGATCTCCCCACGG	IKBKB	ENSG00000104365	-0.2687121789001298	[3,3]	[4,0]	-4	hSpCas9	positive selection	2995145
42308962	42308985	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CGTGATGCACTCAAAGGCCAGGG	IKBKB	ENSG00000104365	-0.21887811948100255	[2,2]	[2,0]	-3	hSpCas9	positive selection	2995146
42305224	42305247	8	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCTGGCTTTAGATCCCGATGG	IKBKB	ENSG00000104365	-0.09500151538052376	[5,4]	[4,2]	-1	hSpCas9	positive selection	2995147
42305187	42305210	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.7064507647435121	[2,2]	[1,0]	-8	hSpCas9	positive selection	3063002
42317722	42317745	8	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATGAGACTCAGATCTCCCCACGG	IKBKB	ENSG00000104365	0.3400942773699473	[3,3]	[4,2]	6	hSpCas9	positive selection	3063003
42308962	42308985	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CGTGATGCACTCAAAGGCCAGGG	IKBKB	ENSG00000104365	-0.3636959806135631	[2,2]	[2,0]	-5	hSpCas9	positive selection	3063004
42305224	42305247	8	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCTGGCTTTAGATCCCGATGG	IKBKB	ENSG00000104365	0.03500420238220364	[5,5]	[4,2]	0	hSpCas9	positive selection	3063005
42293449	42293472		+	24336571	A375	resistance to PLX after 7 days	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	-0.15449443931173512	[9,6]	[7,5]	-5	hSpCas9	positive selection	3120678
42288647	42288670		+	24336571	A375	resistance to PLX after 7 days	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	-0.05883314980945098	[32,35]	[30,33]	-2	hSpCas9	positive selection	3120679
42290167	42290190		-	24336571	A375	resistance to PLX after 7 days	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.24043694609160937	[79,83]	[73,63]	-7	hSpCas9	positive selection	3120680
42290252	42290275		-	24336571	A375	resistance to PLX after 7 days	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	-0.14169348209976285	[44,41]	[38,38]	-4	hSpCas9	positive selection	3120682
42293491	42293514		+	24336571	A375	resistance to PLX after 7 days	CTCACCTTGCTGAGTGACATTGG	IKBKB	ENSG00000104365	-0.09934332816007241	[20,13]	[15,16]	-3	hSpCas9	positive selection	3120683
42288677	42288700		+	24336571	A375	resistance to PLX after 7 days	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.10304963975512305	[8,8]	[8,6]	-3	hSpCas9	positive selection	3120684
42293449	42293472		+	24336571	A375	resistance to PLX after 14 days	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	1.25298245262878	[8,4]	[7,7]	8	hSpCas9	positive selection	3178471
42288647	42288670		+	24336571	A375	resistance to PLX after 14 days	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	-0.9464227574150679	[45,38]	[9,9]	-9	hSpCas9	positive selection	3178472
42290167	42290190		-	24336571	A375	resistance to PLX after 14 days	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.3482939302063546	[71,90]	[28,29]	-4	hSpCas9	positive selection	3178473
42290252	42290275		-	24336571	A375	resistance to PLX after 14 days	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.39157432052471863	[37,36]	[21,23]	4	hSpCas9	positive selection	3178475
42293491	42293514		+	24336571	A375	resistance to PLX after 14 days	CTCACCTTGCTGAGTGACATTGG	IKBKB	ENSG00000104365	-0.23686927910685598	[17,11]	[4,5]	-3	hSpCas9	positive selection	3178476
42288677	42288700		+	24336571	A375	resistance to PLX after 14 days	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.13619506730212333	[9,6]	[3,3]	1	hSpCas9	positive selection	3178477
42293449	42293472		+	24336571	A375	viability after 7 days	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	-0.04348914934276449	[8]	[9,6]	0	hSpCas9	negative selection	3236264
42288647	42288670		+	24336571	A375	viability after 7 days	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	-0.1326904707707306	[39]	[32,35]	-2	hSpCas9	negative selection	3236265
42290167	42290190		-	24336571	A375	viability after 7 days	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	1.0775199265421755	[40]	[79,83]	9	hSpCas9	negative selection	3236266
42290252	42290275		-	24336571	A375	viability after 7 days	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.28458304727824535	[36]	[44,41]	4	hSpCas9	negative selection	3236268
42293491	42293514		+	24336571	A375	viability after 7 days	CTCACCTTGCTGAGTGACATTGG	IKBKB	ENSG00000104365	0.5570220954198364	[12]	[20,13]	8	hSpCas9	negative selection	3236269
42288677	42288700		+	24336571	A375	viability after 7 days	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.004906325803446743	[8]	[8,8]	0	hSpCas9	negative selection	3236270
42293449	42293472		+	24336571	A375	viability after 14 days	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	-0.27424853323451115	[8]	[8,4]	-3	hSpCas9	negative selection	3294057
42288647	42288670		+	24336571	A375	viability after 14 days	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	0.17857039112906414	[39]	[45,38]	2	hSpCas9	negative selection	3294058
42290167	42290190		-	24336571	A375	viability after 14 days	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	1.079486608988144	[40]	[71,90]	9	hSpCas9	negative selection	3294059
42290252	42290275		-	24336571	A375	viability after 14 days	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.0989737754240847	[36]	[37,36]	1	hSpCas9	negative selection	3294061
42293491	42293514		+	24336571	A375	viability after 14 days	CTCACCTTGCTGAGTGACATTGG	IKBKB	ENSG00000104365	0.31771979627563257	[12]	[17,11]	4	hSpCas9	negative selection	3294062
42288677	42288700		+	24336571	A375	viability after 14 days	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.03587202015793434	[8]	[9,6]	0	hSpCas9	negative selection	3294063
42290167	42290190	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.10899600279998067	[164,164]	[0,0]	0	hSpCas9	positive selection	3374004
42272190	42272213	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.4569193062202874	[419,419]	[1,1]	-3	hSpCas9	positive selection	3374005
42288714	42288737	8	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	-0.7815927778464674	[262,262]	[0,0]	-5	hSpCas9	positive selection	3374006
42305187	42305210	8	-	26780180	HT29	viability (Avana library 4 designs)	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	1.61236633910131	[]	[]	6	hSpCas9	negative selection	3432507
42317721	42317744	8	+	26780180	HT29	viability (Avana library 4 designs)	ATGAGACTCAGATCTCCCCACGG	IKBKB	ENSG00000104365	1.31278600335599	[]	[]	5	hSpCas9	negative selection	3432508
42308962	42308985	8	-	26780180	HT29	viability (Avana library 4 designs)	CGTGATGCACTCAAAGGCCAGGG	IKBKB	ENSG00000104365	1.09898132046638	[]	[]	4	hSpCas9	negative selection	3432509
42305224	42305247	8	-	26780180	HT29	viability (Avana library 4 designs)	TTTCTGGCTTTAGATCCCGATGG	IKBKB	ENSG00000104365	0.095198141753196	[]	[]	0	hSpCas9	negative selection	3432510
42317721	42317744	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAGACTCAGATCTCCCCACGG	IKBKB	ENSG00000104365	0.444395685346537	[]	[]	0	hSpCas9	negative selection	3518683
42305224	42305247	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCTGGCTTTAGATCCCGATGG	IKBKB	ENSG00000104365	-1.21457878719085	[]	[]	-1	hSpCas9	negative selection	3518684
42305187	42305210	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-2.27473968004691	[]	[]	-3	hSpCas9	negative selection	3518685
42308962	42308985	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	CGTGATGCACTCAAAGGCCAGGG	IKBKB	ENSG00000104365	3.05513865222246	[]	[]	5	hSpCas9	negative selection	3518686
42306419	42306442	8	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCTTACCAGGTACTGCAGGG	IKBKB	ENSG00000104365	-0.912468495029268	[]	[]	-1	hSpCas9	negative selection	3518687
42305254	42305277	8	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGCAGCAAGGAGAACAGAGGG	IKBKB	ENSG00000104365	1.37344001359478	[]	[]	2	hSpCas9	negative selection	3518688
42317721	42317744	8	+	26780180	A375	viability (Avana lentiGuide)	ATGAGACTCAGATCTCCCCACGG	IKBKB	ENSG00000104365	2.32423019798068	[]	[]	2	hSpCas9	negative selection	3627342
42305224	42305247	8	-	26780180	A375	viability (Avana lentiGuide)	TTTCTGGCTTTAGATCCCGATGG	IKBKB	ENSG00000104365	-0.382787414153352	[]	[]	0	hSpCas9	negative selection	3627343
42305187	42305210	8	-	26780180	A375	viability (Avana lentiGuide)	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	6.46570721352562	[]	[]	5	hSpCas9	negative selection	3627344
42308962	42308985	8	-	26780180	A375	viability (Avana lentiGuide)	CGTGATGCACTCAAAGGCCAGGG	IKBKB	ENSG00000104365	4.82419457832462	[]	[]	4	hSpCas9	negative selection	3627345
42306419	42306442	8	-	26780180	A375	viability (Avana lentiGuide)	ACTTCTTACCAGGTACTGCAGGG	IKBKB	ENSG00000104365	-6.81673723236801	[]	[]	-9	hSpCas9	negative selection	3627346
42305254	42305277	8	+	26780180	A375	viability (Avana lentiGuide)	CCTGCAGCAAGGAGAACAGAGGG	IKBKB	ENSG00000104365	-5.3355540222882	[]	[]	-8	hSpCas9	negative selection	3627347
42317721	42317744	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAGACTCAGATCTCCCCACGG	IKBKB	ENSG00000104365	-0.005208187658497759	[5]	[4,5]	0	hSpCas9	positive selection	3736001
42305224	42305247	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCTGGCTTTAGATCCCGATGG	IKBKB	ENSG00000104365	-0.15232609419634097	[6]	[5,5]	-2	hSpCas9	positive selection	3736002
42305187	42305210	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.12015950716588138	[4]	[6,2]	-2	hSpCas9	positive selection	3736003
42308962	42308985	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGTGATGCACTCAAAGGCCAGGG	IKBKB	ENSG00000104365	0.3298050509878087	[4]	[6,4]	8	hSpCas9	positive selection	3736004
42306419	42306442	8	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCTTACCAGGTACTGCAGGG	IKBKB	ENSG00000104365	-0.20735218696663626	[5]	[5,3]	-3	hSpCas9	positive selection	3736005
42305254	42305277	8	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGCAGCAAGGAGAACAGAGGG	IKBKB	ENSG00000104365	0.01662479307045596	[5]	[5,5]	0	hSpCas9	positive selection	3736006
42317721	42317744	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAGACTCAGATCTCCCCACGG	IKBKB	ENSG00000104365	-0.23319297293511887	[5]	[2,4]	-3	hSpCas9	positive selection	3844608
42305224	42305247	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCTGGCTTTAGATCCCGATGG	IKBKB	ENSG00000104365	0.0985358047337897	[6]	[7,5]	2	hSpCas9	positive selection	3844609
42305187	42305210	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.11975385460668742	[4]	[4,3]	2	hSpCas9	positive selection	3844610
42308962	42308985	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGTGATGCACTCAAAGGCCAGGG	IKBKB	ENSG00000104365	0.10971679354793287	[4]	[2,4]	2	hSpCas9	positive selection	3844611
42306419	42306442	8	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCTTACCAGGTACTGCAGGG	IKBKB	ENSG00000104365	0.2315172024207494	[5]	[4,6]	6	hSpCas9	positive selection	3844612
42305254	42305277	8	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGCAGCAAGGAGAACAGAGGG	IKBKB	ENSG00000104365	0.2968085161309974	[5]	[6,6]	8	hSpCas9	positive selection	3844613
42290167	42290190	8	-	26780180	A375	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.513791461480376	[]	[]	1	hSpCas9	negative selection	3950576
42290252	42290275	8	-	26780180	A375	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.274923359373908	[]	[]	0	hSpCas9	negative selection	3950577
42272174	42272197	8	+	26780180	A375	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	1.05107984181148	[]	[]	5	hSpCas9	negative selection	3950578
42288714	42288737	8	-	26780180	A375	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	1.20291312418062	[]	[]	6	hSpCas9	negative selection	3950579
42272190	42272213	8	-	26780180	A375	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	1.11781699982305	[]	[]	5	hSpCas9	negative selection	3950580
42288677	42288700	8	+	26780180	A375	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.212285588013364	[]	[]	0	hSpCas9	negative selection	3950581
42290167	42290190	8	-	26780180	HT29	viability (GeCKOv2 library)	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	1.29023219107108	[]	[]	6	hSpCas9	negative selection	4058542
42290252	42290275	8	-	26780180	HT29	viability (GeCKOv2 library)	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	-0.268133239120608	[]	[]	-6	hSpCas9	negative selection	4058543
42272174	42272197	8	+	26780180	HT29	viability (GeCKOv2 library)	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.69600870377856	[]	[]	2	hSpCas9	negative selection	4058544
42288714	42288737	8	-	26780180	HT29	viability (GeCKOv2 library)	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	1.30391608654212	[]	[]	6	hSpCas9	negative selection	4058545
42272190	42272213	8	-	26780180	HT29	viability (GeCKOv2 library)	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.862728407605508	[]	[]	3	hSpCas9	negative selection	4058546
42288677	42288700	8	+	26780180	HT29	viability (GeCKOv2 library)	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	1.47046227414094	[]	[]	7	hSpCas9	negative selection	4058547
42293449	42293472	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.09505285024383026	[2]	[1,2]	2	hSpCas9	positive selection	4144310
42288647	42288670	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	0.12356916089359216	[4]	[3,3]	3	hSpCas9	positive selection	4144311
42290167	42290190	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.2700062188131802	[5]	[4,4]	6	hSpCas9	positive selection	4144312
42290252	42290275	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.2019352473944554	[5]	[3,4]	5	hSpCas9	positive selection	4144314
42293491	42293514	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACCTTGCTGAGTGACATTGG	IKBKB	ENSG00000104365	-0.10765765205022917	[3]	[1,2]	-3	hSpCas9	positive selection	4144315
42288677	42288700	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.18498683746343023	[3]	[2,1]	5	hSpCas9	positive selection	4144316
42293449	42293472	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	-0.15685031983771885	[3]	[0,3,1,0]	-2	hSpCas9	positive selection	4208332
42288647	42288670	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGATTGCCATCAAGCAGTGCCGG	IKBKB	ENSG00000104365	1.0488852286286052	[5]	[5,5,4,5]	7	hSpCas9	positive selection	4208333
42290167	42290190	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.9118005041146157	[5]	[5,4,5,3]	6	hSpCas9	positive selection	4208334
42290252	42290275	8	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.7372671497591581	[5]	[5,2,1,4]	5	hSpCas9	positive selection	4208336
42293491	42293514	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACCTTGCTGAGTGACATTGG	IKBKB	ENSG00000104365	0.6289243197445501	[3]	[2,3,3,0]	4	hSpCas9	positive selection	4208337
42288677	42288700	8	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	1.7218709814647901	[0]	[1,1,0,0]	9	hSpCas9	positive selection	4208338
42272174	42272197	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.16376270464113246	[1]	[1,1]	3	hSpCas9	positive selection	4276599
42288677	42288700	8	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.5608126513926379	[2]	[2,2]	9	hSpCas9	positive selection	4276600
42290252	42290275	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.3495674575922849	[4]	[4,4]	7	hSpCas9	positive selection	4276601
42290167	42290190	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.290501441628475	[3]	[2,3]	6	hSpCas9	positive selection	4340857
42272190	42272213	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.21375918083912526	[3]	[3,3]	4	hSpCas9	positive selection	4340858
42288714	42288737	8	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	-0.24432065312733028	[3]	[3,0]	-5	hSpCas9	positive selection	4340859
42290253	42290275	8	+	27760321	OCIAML3	viability	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.16382651326016529	[207,172]	[150,185]	2	hSpCas9	negative selection	4409205
42305187	42305209	8	-	27760321	OCIAML3	viability	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.9830890934682253	[348,306]	[99,167]	-7	hSpCas9	negative selection	4409206
42308930	42308952	8	+	27760321	OCIAML3	viability	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-0.31369310230091363	[312,238]	[134,220]	-3	hSpCas9	negative selection	4409207
42316272	42316294	8	+	27760321	OCIAML3	viability	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.7763456602254561	[402,334]	[466,524]	8	hSpCas9	negative selection	4409208
42316853	42316875	8	-	27760321	OCIAML3	viability	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.6328805595249841	[686,578]	[812,701]	7	hSpCas9	negative selection	4409209
42290253	42290275	8	+	27760321	OCIAML2	viability	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.5389126651834458	[207,172]	[209,239]	7	hSpCas9	negative selection	4492668
42305187	42305209	8	-	27760321	OCIAML2	viability	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.33688699608967704	[348,306]	[153,282]	-4	hSpCas9	negative selection	4492669
42308930	42308952	8	+	27760321	OCIAML2	viability	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-0.08926545198241798	[312,238]	[149,284]	-1	hSpCas9	negative selection	4492670
42316272	42316294	8	+	27760321	OCIAML2	viability	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	-0.7538961575845635	[402,334]	[117,252]	-7	hSpCas9	negative selection	4492671
42316853	42316875	8	-	27760321	OCIAML2	viability	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.09698177231032612	[686,578]	[555,531]	1	hSpCas9	negative selection	4492672
42290253	42290275	8	+	27760321	MV411	viability	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.20955153671807025	[207,172]	[77,244]	1	hSpCas9	negative selection	4576131
42305187	42305209	8	-	27760321	MV411	viability	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.3088293403367014	[348,306]	[249,293]	2	hSpCas9	negative selection	4576132
42308930	42308952	8	+	27760321	MV411	viability	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-3.630882802415859	[312,238]	[0,34]	-9	hSpCas9	negative selection	4576133
42316272	42316294	8	+	27760321	MV411	viability	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.2278074227858029	[402,334]	[205,400]	1	hSpCas9	negative selection	4576134
42316853	42316875	8	-	27760321	MV411	viability	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.2861355600819211	[686,578]	[335,764]	2	hSpCas9	negative selection	4576135
42290253	42290275	8	+	27760321	HL60	viability	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.47459507350809016	[207,172]	[111,110]	-5	hSpCas9	negative selection	4659594
42305187	42305209	8	-	27760321	HL60	viability	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.6626445095323971	[348,306]	[482,359]	7	hSpCas9	negative selection	4659595
42308930	42308952	8	+	27760321	HL60	viability	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	0.4804285146420372	[312,238]	[282,342]	6	hSpCas9	negative selection	4659596
42316272	42316294	8	+	27760321	HL60	viability	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	-0.4758239248703597	[402,334]	[275,151]	-5	hSpCas9	negative selection	4659597
42316853	42316875	8	-	27760321	HL60	viability	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	-0.05650875700407321	[686,578]	[573,411]	0	hSpCas9	negative selection	4659598
42290253	42290275	8	+	27760321	HT1080	viability	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.9556504058353696	[172,134]	[86,153]	5	hSpCas9	negative selection	4743057
42305187	42305209	8	-	27760321	HT1080	viability	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.2764336137948437	[306,239]	[162,9]	-1	hSpCas9	negative selection	4743058
42308930	42308952	8	+	27760321	HT1080	viability	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	0.4170157870134139	[238,186]	[24,209]	2	hSpCas9	negative selection	4743059
42316272	42316294	8	+	27760321	HT1080	viability	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.8052023547679312	[334,261]	[87,338]	4	hSpCas9	negative selection	4743060
42316853	42316875	8	-	27760321	HT1080	viability	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	1.4807962861958766	[578,451]	[618,522]	7	hSpCas9	negative selection	4743061
42290253	42290275	8	+	27760321	HT29	viability after 7 days	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.6673214589187668	[172,134]	[540,113,319]	8	hSpCas9	negative selection	4826520
42305187	42305209	8	-	27760321	HT29	viability after 7 days	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.26732638213812127	[306,239]	[256,380,234]	-4	hSpCas9	negative selection	4826521
42308930	42308952	8	+	27760321	HT29	viability after 7 days	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	0.2154334908992548	[238,186]	[274,403,269]	3	hSpCas9	negative selection	4826522
42316272	42316294	8	+	27760321	HT29	viability after 7 days	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.4550330874805797	[334,261]	[409,555,592]	7	hSpCas9	negative selection	4826523
42316853	42316875	8	-	27760321	HT29	viability after 7 days	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.5122103093256706	[578,451]	[1097,866,892]	7	hSpCas9	negative selection	4826524
42290253	42290275	8	+	27760321	HT29	viability after 25 days	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.8038264354507303	[172,134]	[222,176,551]	8	hSpCas9	negative selection	4909983
42305187	42305209	8	-	27760321	HT29	viability after 25 days	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.04397379665293627	[306,239]	[339,364,252]	0	hSpCas9	negative selection	4909984
42308930	42308952	8	+	27760321	HT29	viability after 25 days	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	0.6103452611815872	[238,186]	[197,515,415]	7	hSpCas9	negative selection	4909985
42316272	42316294	8	+	27760321	HT29	viability after 25 days	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.8137072905969605	[334,261]	[546,727,517]	8	hSpCas9	negative selection	4909986
42316853	42316875	8	-	27760321	HT29	viability after 25 days	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.3100275699941065	[578,451]	[828,725,616]	3	hSpCas9	negative selection	4909987
42290253	42290275	8	+	27760321	HT29	viability after 22 days	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	1.1501371886995968	[172,134]	[501,329,349]	9	hSpCas9	negative selection	4993446
42305187	42305209	8	-	27760321	HT29	viability after 22 days	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.5437027425129835	[306,239]	[116,367,167]	-5	hSpCas9	negative selection	4993447
42308930	42308952	8	+	27760321	HT29	viability after 22 days	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	0.42365839283576834	[238,186]	[279,314,397]	4	hSpCas9	negative selection	4993448
42316272	42316294	8	+	27760321	HT29	viability after 22 days	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.5478224635521467	[334,261]	[494,600,416]	6	hSpCas9	negative selection	4993449
42316853	42316875	8	-	27760321	HT29	viability after 22 days	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.4497543201620211	[578,451]	[983,768,682]	5	hSpCas9	negative selection	4993450
42290253	42290275	8	+	27760321	HT29	viability after 19 days	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	1.2260846887468932	[172,134]	[501,138,596]	9	hSpCas9	negative selection	5076909
42305187	42305209	8	-	27760321	HT29	viability after 19 days	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.3856566260818592	[306,239]	[255,333,133]	-4	hSpCas9	negative selection	5076910
42308930	42308952	8	+	27760321	HT29	viability after 19 days	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-0.4560560247337393	[238,186]	[115,198,209]	-4	hSpCas9	negative selection	5076911
42316272	42316294	8	+	27760321	HT29	viability after 19 days	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.07069798906866259	[334,261]	[393,347,337]	0	hSpCas9	negative selection	5076912
42316853	42316875	8	-	27760321	HT29	viability after 19 days	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.32163994387502726	[578,451]	[942,697,595]	3	hSpCas9	negative selection	5076913
42290253	42290275	8	+	27760321	HT29	viability after 16 days	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.5937673493039823	[172,134]	[311,295,175]	7	hSpCas9	negative selection	5160372
42305187	42305209	8	-	27760321	HT29	viability after 16 days	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.22904736501162093	[306,239]	[397,346,334]	2	hSpCas9	negative selection	5160373
42308930	42308952	8	+	27760321	HT29	viability after 16 days	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-0.10391501911433731	[238,186]	[95,390,161]	-1	hSpCas9	negative selection	5160374
42316272	42316294	8	+	27760321	HT29	viability after 16 days	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.5390780381282634	[334,261]	[441,362,649]	6	hSpCas9	negative selection	5160375
42316853	42316875	8	-	27760321	HT29	viability after 16 days	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	0.6006451865584558	[578,451]	[1155,728,768]	7	hSpCas9	negative selection	5160376
42290253	42290275	8	+	27760321	HT29	viability after 13 days	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.5301673437020639	[172,134]	[175,354,243]	6	hSpCas9	negative selection	5243835
42305187	42305209	8	-	27760321	HT29	viability after 13 days	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.005036333248349345	[306,239]	[511,219,221]	0	hSpCas9	negative selection	5243836
42308930	42308952	8	+	27760321	HT29	viability after 13 days	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-0.30972812592091303	[238,186]	[87,218,285]	-4	hSpCas9	negative selection	5243837
42316272	42316294	8	+	27760321	HT29	viability after 13 days	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.6303959228722145	[334,261]	[437,710,463]	7	hSpCas9	negative selection	5243838
42316853	42316875	8	-	27760321	HT29	viability after 13 days	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	-0.30135469878659255	[578,451]	[491,600,369]	-4	hSpCas9	negative selection	5243839
42290253	42290275	8	+	27760321	HT29	viability after 10 days	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.7408222054945839	[172,134]	[207,353,400]	8	hSpCas9	negative selection	5327298
42305187	42305209	8	-	27760321	HT29	viability after 10 days	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.510053525191082	[306,239]	[277,274,168]	-6	hSpCas9	negative selection	5327299
42308930	42308952	8	+	27760321	HT29	viability after 10 days	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-0.7255028356828619	[238,186]	[101,215,165]	-7	hSpCas9	negative selection	5327300
42316272	42316294	8	+	27760321	HT29	viability after 10 days	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.5831114633530864	[334,261]	[576,467,625]	7	hSpCas9	negative selection	5327301
42316853	42316875	8	-	27760321	HT29	viability after 10 days	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	-0.043086662175660206	[578,451]	[532,805,541]	0	hSpCas9	negative selection	5327302
42290253	42290275	8	+	27760321	MOLM13	viability	CAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.39299376963830235	[207,172]	[141,29]	-3	hSpCas9	negative selection	5410761
42305187	42305209	8	-	27760321	MOLM13	viability	TGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.34218736558931573	[348,306]	[339,143]	2	hSpCas9	negative selection	5410762
42308930	42308952	8	+	27760321	MOLM13	viability	CACAGTGACCGTCGACTACTGG	IKBKB	ENSG00000104365	-2.672232535933399	[312,238]	[20,26]	-8	hSpCas9	negative selection	5410763
42316272	42316294	8	+	27760321	MOLM13	viability	GGGGCACGGATCCCACGTATGG	IKBKB	ENSG00000104365	0.5159333500531198	[402,334]	[236,346]	3	hSpCas9	negative selection	5410764
42316853	42316875	8	-	27760321	MOLM13	viability	CTTATCGGGGATCAACGCCAGG	IKBKB	ENSG00000104365	-1.0580309810959991	[686,578]	[205,140]	-6	hSpCas9	negative selection	5410765
42271465	42271488	8	+	27661255	K562	viability	GACAGGTGAGTCCCCCTCGTGGG	IKBKB	ENSG00000104365	0.42555745093885644	[55,151]	[126,94]	9	dCas9-KRAB	negative selection	5486466
42271782	42271805	8	+	27661255	K562	viability	GCCCCTGGTGGAGTCAGCTGGGG	IKBKB	ENSG00000104365	-0.014453146969359176	[207,249]	[193,168]	0	dCas9-KRAB	negative selection	5486467
42271395	42271418	8	-	27661255	K562	viability	GGGCTGGGGCGGCCAAACCCGGG	IKBKB	ENSG00000104365	0.24549889543186476	[349,341]	[431,238]	8	dCas9-KRAB	negative selection	5486468
42272174	42272197	8	+	27260156	BXPC3	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.5680551620104781	[152]	[255,221,235,230]	9	hSpCas9	negative selection	5549059
42288677	42288700	8	+	27260156	BXPC3	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.5336026252088213	[215]	[309,215,506,277]	9	hSpCas9	negative selection	5549060
42290252	42290275	8	-	27260156	BXPC3	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.40789012849973627	[1156]	[1298,1726,1637,1794]	8	hSpCas9	negative selection	5549061
42290167	42290190	8	-	27260156	BXPC3	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.0012104290953608432	[608]	[560,587,684,729]	0	hSpCas9	negative selection	5613317
42272190	42272213	8	-	27260156	BXPC3	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.07213648373658965	[946]	[931,879,1074,1326]	1	hSpCas9	negative selection	5613318
42288714	42288737	8	-	27260156	BXPC3	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.2756141606805387	[549]	[492,771,688,863]	6	hSpCas9	negative selection	5613319
42272174	42272197	8	+	27260156	A673	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.3903369134403947	[152]	[288,265,189,221]	8	hSpCas9	negative selection	5670310
42288677	42288700	8	+	27260156	A673	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.12049817979300648	[215]	[266,263,249,348]	3	hSpCas9	negative selection	5670311
42290252	42290275	8	-	27260156	A673	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.42086136094884097	[1156]	[2111,1820,1664,1869]	8	hSpCas9	negative selection	5670312
42290167	42290190	8	-	27260156	A673	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.025261993714438935	[608]	[803,682,687,812]	0	hSpCas9	negative selection	5734568
42272190	42272213	8	-	27260156	A673	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.03110680548788114	[946]	[1326,954,1196,1191]	0	hSpCas9	negative selection	5734569
42288714	42288737	8	-	27260156	A673	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.02873176873197167	[549]	[697,712,577,708]	0	hSpCas9	negative selection	5734570
42272174	42272197	8	+	27260156	A375	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.4063115296700279	[152]	[283,272,159,234]	6	hSpCas9	negative selection	5791561
42288677	42288700	8	+	27260156	A375	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.25609120690536	[215]	[211,273,137,226]	-4	hSpCas9	negative selection	5791562
42290252	42290275	8	-	27260156	A375	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.4017153550481085	[1156]	[1896,1937,1885,1472]	6	hSpCas9	negative selection	5791563
42290167	42290190	8	-	27260156	A375	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.0018409206680214951	[608]	[691,1143,505,579]	0	hSpCas9	negative selection	5855819
42272190	42272213	8	-	27260156	A375	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.13565150670650672	[946]	[1065,1232,1442,1125]	2	hSpCas9	negative selection	5855820
42288714	42288737	8	-	27260156	A375	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.44847722631895237	[549]	[627,1015,892,971]	6	hSpCas9	negative selection	5855821
42272174	42272197	8	+	27260156	COLO741	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.16779618073666214	[152]	[232,200,224]	3	hSpCas9	negative selection	5912812
42288677	42288700	8	+	27260156	COLO741	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.0033047036479303404	[215]	[230,234,349]	0	hSpCas9	negative selection	5912813
42290252	42290275	8	-	27260156	COLO741	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.528240890408354	[1156]	[2263,1921,2209]	9	hSpCas9	negative selection	5912814
42290167	42290190	8	-	27260156	COLO741	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.23354904266843263	[608]	[949,804,984]	5	hSpCas9	negative selection	5977070
42272190	42272213	8	-	27260156	COLO741	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.24025966017804556	[946]	[1634,1591,1099]	5	hSpCas9	negative selection	5977071
42288714	42288737	8	-	27260156	COLO741	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.08400738409607497	[549]	[791,729,716]	1	hSpCas9	negative selection	5977072
42272174	42272197	8	+	27260156	CAL120	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	-1.324206847726262	[152]	[97,35,96]	-9	hSpCas9	negative selection	6034063
42288677	42288700	8	+	27260156	CAL120	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.8565501261388391	[215]	[159,193,93]	-8	hSpCas9	negative selection	6034064
42290252	42290275	8	-	27260156	CAL120	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.3342717492915772	[1156]	[1812,1793,1836]	5	hSpCas9	negative selection	6034065
42290167	42290190	8	-	27260156	CAL120	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.31411616859090735	[608]	[994,1171,671]	5	hSpCas9	negative selection	6098321
42272190	42272213	8	-	27260156	CAL120	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.24959285627489003	[946]	[1200,822,980]	-4	hSpCas9	negative selection	6098322
42288714	42288737	8	-	27260156	CAL120	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	-0.055861823940762834	[549]	[534,683,735]	-1	hSpCas9	negative selection	6098323
42272174	42272197	8	+	27260156	CADOES1	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	-0.5002299678508779	[152]	[101,135,101,60]	-7	hSpCas9	negative selection	6155314
42288677	42288700	8	+	27260156	CADOES1	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.3978531621890067	[215]	[111,145,147,205]	-6	hSpCas9	negative selection	6155315
42290252	42290275	8	-	27260156	CADOES1	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.21384613321148005	[1156]	[1108,1093,1540,1247]	3	hSpCas9	negative selection	6155316
42290167	42290190	8	-	27260156	CADOES1	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.19286154568574762	[608]	[390,525,529,536]	-3	hSpCas9	negative selection	6219572
42272190	42272213	8	-	27260156	CADOES1	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.09780849351535803	[946]	[777,1041,642,829]	-2	hSpCas9	negative selection	6219573
42288714	42288737	8	-	27260156	CADOES1	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.13026741163448216	[549]	[476,600,544,618]	2	hSpCas9	negative selection	6219574
42272174	42272197	8	+	27260156	EWS502	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.7126132907876137	[152]	[300,330,134,286]	9	hSpCas9	negative selection	6276565
42288677	42288700	8	+	27260156	EWS502	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.17557183378117636	[215]	[184,355,256,237]	3	hSpCas9	negative selection	6276566
42290252	42290275	8	-	27260156	EWS502	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.6003277261032627	[1156]	[1705,1948,1894,1891]	9	hSpCas9	negative selection	6276567
42290167	42290190	8	-	27260156	EWS502	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.2974979745419244	[608]	[520,503,548,524]	-5	hSpCas9	negative selection	6340823
42272190	42272213	8	-	27260156	EWS502	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.02146607424656044	[946]	[828,1005,999,1143]	0	hSpCas9	negative selection	6340824
42288714	42288737	8	-	27260156	EWS502	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.1462651370355735	[549]	[623,592,430,951]	2	hSpCas9	negative selection	6340825
42272174	42272197	8	+	27260156	EW8	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.4834021806999871	[152]	[154,103,252,164]	8	hSpCas9	negative selection	6397816
42288677	42288700	8	+	27260156	EW8	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.5021234061807637	[215]	[180,282,137,399]	8	hSpCas9	negative selection	6397817
42290252	42290275	8	-	27260156	EW8	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5077495374974861	[1156]	[1394,1354,1134,1483]	8	hSpCas9	negative selection	6397818
42290167	42290190	8	-	27260156	EW8	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.1426974904542006	[608]	[824,531,420,451]	2	hSpCas9	negative selection	6462074
42272190	42272213	8	-	27260156	EW8	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.19004812696014972	[946]	[1196,950,709,705]	3	hSpCas9	negative selection	6462075
42288714	42288737	8	-	27260156	EW8	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.4481629249911925	[549]	[683,770,382,639]	7	hSpCas9	negative selection	6462076
42272174	42272197	8	+	27260156	CORL105	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.6604894625194487	[152]	[255,303,326,250]	9	hSpCas9	negative selection	6519067
42288677	42288700	8	+	27260156	CORL105	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.12151608993783292	[215]	[322,264,310,208]	2	hSpCas9	negative selection	6519068
42290252	42290275	8	-	27260156	CORL105	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.25701259635423956	[1156]	[1648,1472,1941,1464]	5	hSpCas9	negative selection	6519069
42290167	42290190	8	-	27260156	CORL105	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.11517450463219753	[608]	[665,566,842,587]	-2	hSpCas9	negative selection	6583325
42272190	42272213	8	-	27260156	CORL105	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.11289109706236844	[946]	[878,894,1188,1159]	-2	hSpCas9	negative selection	6583326
42288714	42288737	8	-	27260156	CORL105	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.14602270246187846	[549]	[699,736,807,618]	2	hSpCas9	negative selection	6583327
42272174	42272197	8	+	27260156	HS294T	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.07871759393682232	[152]	[53,79,57,56]	1	hSpCas9	negative selection	6640318
42288677	42288700	8	+	27260156	HS294T	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.6662942850435298	[215]	[253,96,70,89]	8	hSpCas9	negative selection	6640319
42290252	42290275	8	-	27260156	HS294T	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5480600384563978	[1156]	[521,552,733,854]	7	hSpCas9	negative selection	6640320
42290167	42290190	8	-	27260156	HS294T	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.63502524818483	[608]	[136,97,193,185]	-7	hSpCas9	negative selection	6704576
42272190	42272213	8	-	27260156	HS294T	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.10731057507996833	[946]	[378,350,351,517]	1	hSpCas9	negative selection	6704577
42288714	42288737	8	-	27260156	HS294T	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	-0.027075344275226843	[549]	[140,172,153,406]	0	hSpCas9	negative selection	6704578
42272174	42272197	8	+	27260156	HCC44	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	-2.2781450586216137	[152]	[19,44,32,40]	-9	hSpCas9	negative selection	6761569
42288677	42288700	8	+	27260156	HCC44	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-1.6398179816356784	[215]	[78,31,148,71]	-9	hSpCas9	negative selection	6761570
42290252	42290275	8	-	27260156	HCC44	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	-0.2108632259253025	[1156]	[1047,1047,1214,1217]	-3	hSpCas9	negative selection	6761571
42290167	42290190	8	-	27260156	HCC44	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.06863727257602459	[608]	[710,738,654,761]	1	hSpCas9	negative selection	6825827
42272190	42272213	8	-	27260156	HCC44	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.1806863610647511	[946]	[1082,690,1015,1039]	-3	hSpCas9	negative selection	6825828
42288714	42288737	8	-	27260156	HCC44	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.09018700251843279	[549]	[874,483,832,529]	1	hSpCas9	negative selection	6825829
42272174	42272197	8	+	27260156	G402	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.5188041005935768	[152]	[121,186,101,614]	6	hSpCas9	negative selection	6882820
42288677	42288700	8	+	27260156	G402	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.24060275549775356	[215]	[217,358,288,364]	3	hSpCas9	negative selection	6882821
42290252	42290275	8	-	27260156	G402	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.4046732886697426	[1156]	[2302,1806,2048,1391]	5	hSpCas9	negative selection	6882822
42290167	42290190	8	-	27260156	G402	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.037752906733811764	[608]	[685,694,693,948]	0	hSpCas9	negative selection	6947078
42272190	42272213	8	-	27260156	G402	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.2895387024616467	[946]	[1672,1719,1075,1238]	3	hSpCas9	negative selection	6947079
42288714	42288737	8	-	27260156	G402	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.32738639063612274	[549]	[1296,419,885,804]	4	hSpCas9	negative selection	6947080
42272174	42272197	8	+	27260156	L33	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.014346717211235704	[152]	[168,62,71,179]	0	hSpCas9	negative selection	7004071
42288677	42288700	8	+	27260156	L33	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.23486392380563437	[215]	[156,89,227,279]	5	hSpCas9	negative selection	7004072
42290252	42290275	8	-	27260156	L33	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.4565288257943747	[1156]	[1384,691,1046,1615]	8	hSpCas9	negative selection	7004073
42290167	42290190	8	-	27260156	L33	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.11379025850945679	[608]	[535,248,318,599]	-3	hSpCas9	negative selection	7068329
42272190	42272213	8	-	27260156	L33	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.14443513898278615	[946]	[822,322,619,830]	-3	hSpCas9	negative selection	7068330
42288714	42288737	8	-	27260156	L33	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	-0.028310811093073485	[549]	[514,237,378,459]	0	hSpCas9	negative selection	7068331
42272174	42272197	8	+	27260156	K562	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	-0.10070646763984237	[152]	[89,140,63,199]	-1	hSpCas9	negative selection	7125322
42288677	42288700	8	+	27260156	K562	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.041778654028364004	[215]	[338,55,255,107]	0	hSpCas9	negative selection	7125323
42290252	42290275	8	-	27260156	K562	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.6087459783369691	[1156]	[1819,1119,1807,1511]	7	hSpCas9	negative selection	7125324
42290167	42290190	8	-	27260156	K562	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.2845713146301663	[608]	[489,864,581,686]	3	hSpCas9	negative selection	7189580
42272190	42272213	8	-	27260156	K562	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.42923902442895145	[946]	[1081,1016,1143,1253]	5	hSpCas9	negative selection	7189581
42288714	42288737	8	-	27260156	K562	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.5712034223175845	[549]	[734,878,656,644]	7	hSpCas9	negative selection	7189582
42272174	42272197	8	+	27260156	HT29	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.329613699674391	[152]	[271,188,189,275]	6	hSpCas9	negative selection	7246573
42288677	42288700	8	+	27260156	HT29	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.13623945458518305	[215]	[276,197,410,260]	2	hSpCas9	negative selection	7246574
42290252	42290275	8	-	27260156	HT29	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.44522315832414905	[1156]	[2012,1922,1910,1818]	8	hSpCas9	negative selection	7246575
42290167	42290190	8	-	27260156	HT29	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.21178371473052895	[608]	[617,725,636,583]	-4	hSpCas9	negative selection	7310831
42272190	42272213	8	-	27260156	HT29	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.18632279851637712	[946]	[1466,1445,1436,948]	3	hSpCas9	negative selection	7310832
42288714	42288737	8	-	27260156	HT29	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.2057838903526553	[549]	[811,715,722,819]	4	hSpCas9	negative selection	7310833
42272174	42272197	8	+	27260156	MHHES1	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.3896856645040534	[152]	[356,134,124,274]	7	hSpCas9	negative selection	7367824
42288677	42288700	8	+	27260156	MHHES1	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.10851134676005314	[215]	[335,354,130,242]	2	hSpCas9	negative selection	7367825
42290252	42290275	8	-	27260156	MHHES1	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.41007621893118484	[1156]	[1832,1811,2010,1343]	7	hSpCas9	negative selection	7367826
42290167	42290190	8	-	27260156	MHHES1	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.048556886120725395	[608]	[521,870,772,511]	-1	hSpCas9	negative selection	7432082
42272190	42272213	8	-	27260156	MHHES1	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.1499912169016836	[946]	[1073,983,1017,800]	-3	hSpCas9	negative selection	7432083
42288714	42288737	8	-	27260156	MHHES1	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.11092217933025869	[549]	[472,929,729,556]	2	hSpCas9	negative selection	7432084
42272174	42272197	8	+	27260156	MEWO	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.8240992958055453	[152]	[312,201,256]	9	hSpCas9	negative selection	7489075
42288677	42288700	8	+	27260156	MEWO	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.12248194766266385	[215]	[277,250,141]	2	hSpCas9	negative selection	7489076
42290252	42290275	8	-	27260156	MEWO	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5259993992177614	[1156]	[1529,1566,1572]	9	hSpCas9	negative selection	7489077
42290167	42290190	8	-	27260156	MEWO	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.027751267363730348	[608]	[645,573,534]	0	hSpCas9	negative selection	7553333
42272190	42272213	8	-	27260156	MEWO	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.19203176146849055	[946]	[1092,968,989]	4	hSpCas9	negative selection	7553334
42288714	42288737	8	-	27260156	MEWO	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.25943538511168607	[549]	[738,513,618]	5	hSpCas9	negative selection	7553335
42272174	42272197	8	+	27260156	LNCAPCLONEFGC	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.24211987319250006	[152]	[179,78,157,242]	4	hSpCas9	negative selection	7610326
42288677	42288700	8	+	27260156	LNCAPCLONEFGC	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.13160221050315024	[215]	[186,192,340,156]	2	hSpCas9	negative selection	7610327
42290252	42290275	8	-	27260156	LNCAPCLONEFGC	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.38598826912160966	[1156]	[1305,1127,1769,1349]	6	hSpCas9	negative selection	7610328
42290167	42290190	8	-	27260156	LNCAPCLONEFGC	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.16103091460715357	[608]	[623,436,523,393]	-3	hSpCas9	negative selection	7674584
42272190	42272213	8	-	27260156	LNCAPCLONEFGC	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.10375871489183908	[946]	[837,895,1285,723]	1	hSpCas9	negative selection	7674585
42288714	42288737	8	-	27260156	LNCAPCLONEFGC	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.3664551013184193	[549]	[562,600,904,542]	6	hSpCas9	negative selection	7674586
42272174	42272197	8	+	27260156	PANC0327	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.6169253548734435	[152]	[86,190,259,287]	8	hSpCas9	negative selection	7731577
42288677	42288700	8	+	27260156	PANC0327	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.5631403298172996	[215]	[288,242,481,125]	8	hSpCas9	negative selection	7731578
42290252	42290275	8	-	27260156	PANC0327	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5651035809557061	[1156]	[1733,1119,1556,1739]	8	hSpCas9	negative selection	7731579
42290167	42290190	8	-	27260156	PANC0327	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.6444094368873958	[608]	[957,865,916,647]	8	hSpCas9	negative selection	7795835
42272190	42272213	8	-	27260156	PANC0327	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.26884901642323333	[946]	[1001,835,1128,1108]	4	hSpCas9	negative selection	7795836
42288714	42288737	8	-	27260156	PANC0327	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.1423042271632282	[549]	[550,596,426,574]	2	hSpCas9	negative selection	7795837
42272174	42272197	8	+	27260156	NCIH2009	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.3601038827659133	[152]	[320,321,187]	5	hSpCas9	negative selection	7852828
42288677	42288700	8	+	27260156	NCIH2009	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.2959318590178792	[215]	[299,286,159]	-4	hSpCas9	negative selection	7852829
42290252	42290275	8	-	27260156	NCIH2009	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5520551949813359	[1156]	[2466,2280,2378]	7	hSpCas9	negative selection	7852830
42290167	42290190	8	-	27260156	NCIH2009	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.03415876050199096	[608]	[839,899,751]	0	hSpCas9	negative selection	7917086
42272190	42272213	8	-	27260156	NCIH2009	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.15895879382251987	[946]	[1616,1575,1261]	2	hSpCas9	negative selection	7917087
42288714	42288737	8	-	27260156	NCIH2009	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.0153518582769257	[549]	[732,832,752]	0	hSpCas9	negative selection	7917088
42272174	42272197	8	+	27260156	NCIH1373	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.6597758079377991	[152]	[576,81,155,89]	6	hSpCas9	negative selection	7974079
42288677	42288700	8	+	27260156	NCIH1373	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.4133052167448924	[215]	[272,217,564,58]	4	hSpCas9	negative selection	7974080
42290252	42290275	8	-	27260156	NCIH1373	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.9730195876393171	[1156]	[2658,2896,1912,709]	8	hSpCas9	negative selection	7974081
42290167	42290190	8	-	27260156	NCIH1373	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.2254406299504081	[608]	[556,809,761,271]	2	hSpCas9	negative selection	8038337
42272190	42272213	8	-	27260156	NCIH1373	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.21846970885924843	[946]	[1481,964,1322,322]	2	hSpCas9	negative selection	8038338
42288714	42288737	8	-	27260156	NCIH1373	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.8783004911555617	[549]	[1292,681,1270,358]	8	hSpCas9	negative selection	8038339
42272174	42272197	8	+	27260156	PATU8902	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.3940044714898552	[152]	[179,248,139,627]	4	hSpCas9	negative selection	8095330
42288677	42288700	8	+	27260156	PATU8902	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.9091819799563026	[215]	[653,557,360,756]	8	hSpCas9	negative selection	8095331
42290252	42290275	8	-	27260156	PATU8902	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.715295770758221	[1156]	[3108,2493,1302,4180]	7	hSpCas9	negative selection	8095332
42290167	42290190	8	-	27260156	PATU8902	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.22837364123452536	[608]	[1017,1106,767,1150]	2	hSpCas9	negative selection	8159588
42272190	42272213	8	-	27260156	PATU8902	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.29376362569510084	[946]	[1703,2307,1102,1453]	3	hSpCas9	negative selection	8159589
42288714	42288737	8	-	27260156	PATU8902	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.5932655055509922	[549]	[958,1206,1096,1396]	6	hSpCas9	negative selection	8159590
42272174	42272197	8	+	27260156	PANC1	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.9220495347995544	[152]	[253,259,284,202]	9	hSpCas9	negative selection	8216581
42288677	42288700	8	+	27260156	PANC1	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.5838750873750133	[215]	[280,388,210,252]	8	hSpCas9	negative selection	8216582
42290252	42290275	8	-	27260156	PANC1	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.6381972271734735	[1156]	[1361,2098,1632,1236]	9	hSpCas9	negative selection	8216583
42290167	42290190	8	-	27260156	PANC1	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.1735778130923274	[608]	[487,892,480,556]	2	hSpCas9	negative selection	8280839
42272190	42272213	8	-	27260156	PANC1	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.10229560688265482	[946]	[825,1168,768,788]	1	hSpCas9	negative selection	8280840
42288714	42288737	8	-	27260156	PANC1	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.5096041386457133	[549]	[650,619,659,727]	7	hSpCas9	negative selection	8280841
42272174	42272197	8	+	27260156	PANC0813	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.5579020207998684	[152]	[314,235,307,206]	8	hSpCas9	negative selection	8337832
42288677	42288700	8	+	27260156	PANC0813	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.1539679239304812	[215]	[241,425,218,239]	2	hSpCas9	negative selection	8337833
42290252	42290275	8	-	27260156	PANC0813	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.12292298200273688	[1156]	[1814,1470,1372,1298]	2	hSpCas9	negative selection	8337834
42290167	42290190	8	-	27260156	PANC0813	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.2486281294870665	[608]	[616,478,600,705]	-4	hSpCas9	negative selection	8402090
42272190	42272213	8	-	27260156	PANC0813	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.3071785737722612	[946]	[839,738,916,1082]	-5	hSpCas9	negative selection	8402091
42288714	42288737	8	-	27260156	PANC0813	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.02002642881009084	[549]	[711,653,615,642]	0	hSpCas9	negative selection	8402092
42272174	42272197	8	+	27260156	RDES	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.09811464549064408	[152]	[149,234,181,182]	1	hSpCas9	negative selection	8459083
42288677	42288700	8	+	27260156	RDES	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.13095714665519909	[215]	[201,134,258,336]	-2	hSpCas9	negative selection	8459084
42290252	42290275	8	-	27260156	RDES	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5091900157471267	[1156]	[1530,1689,2203,2258]	7	hSpCas9	negative selection	8459085
42290167	42290190	8	-	27260156	RDES	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.18251206289971128	[608]	[602,657,960,1031]	3	hSpCas9	negative selection	8523341
42272190	42272213	8	-	27260156	RDES	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.11506415911524237	[946]	[1106,1062,1208,1354]	1	hSpCas9	negative selection	8523342
42288714	42288737	8	-	27260156	RDES	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.25000855794608623	[549]	[576,686,865,932]	4	hSpCas9	negative selection	8523343
42272174	42272197	8	+	27260156	PC3	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.34817218652136694	[152]	[97,262,288,184]	7	hSpCas9	negative selection	8580334
42288677	42288700	8	+	27260156	PC3	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.3971667109871556	[215]	[180,195,629,284]	8	hSpCas9	negative selection	8580335
42290252	42290275	8	-	27260156	PC3	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5152113065958586	[1156]	[1014,1734,2892,1543]	9	hSpCas9	negative selection	8580336
42290167	42290190	8	-	27260156	PC3	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.14292382255398517	[608]	[324,464,1104,574]	-3	hSpCas9	negative selection	8644592
42272190	42272213	8	-	27260156	PC3	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.17114777280133675	[946]	[412,800,1781,848]	-4	hSpCas9	negative selection	8644593
42288714	42288737	8	-	27260156	PC3	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.18797212709306885	[549]	[446,587,1083,566]	4	hSpCas9	negative selection	8644594
42272174	42272197	8	+	27260156	PATU8988T	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	-0.8031916167521891	[152]	[49,79,92,117]	-8	hSpCas9	negative selection	8701585
42288677	42288700	8	+	27260156	PATU8988T	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.2982830708449744	[215]	[201,354,234,242]	5	hSpCas9	negative selection	8701586
42290252	42290275	8	-	27260156	PATU8988T	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.03008910322583258	[1156]	[1195,1173,1031,1170]	0	hSpCas9	negative selection	8701587
42290167	42290190	8	-	27260156	PATU8988T	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.06277088408690568	[608]	[437,650,658,507]	-1	hSpCas9	negative selection	8765843
42272190	42272213	8	-	27260156	PATU8988T	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.03850346506447211	[946]	[782,812,1125,825]	0	hSpCas9	negative selection	8765844
42288714	42288737	8	-	27260156	PATU8988T	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	-0.10135160339983446	[549]	[415,468,632,455]	-2	hSpCas9	negative selection	8765845
42272174	42272197	8	+	27260156	T47D	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.08988816360779772	[152]	[209,208,164,172]	2	hSpCas9	negative selection	8822836
42288677	42288700	8	+	27260156	T47D	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.09521887070320334	[215]	[284,227,208,220]	-2	hSpCas9	negative selection	8822837
42290252	42290275	8	-	27260156	T47D	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.32530030124041076	[1156]	[1730,1523,1661,1857]	7	hSpCas9	negative selection	8822838
42290167	42290190	8	-	27260156	T47D	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.10688758626733041	[608]	[642,667,624,699]	-2	hSpCas9	negative selection	8887094
42272190	42272213	8	-	27260156	T47D	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.09130755273006108	[946]	[1202,1068,1279,1155]	2	hSpCas9	negative selection	8887095
42288714	42288737	8	-	27260156	T47D	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.2564293379052688	[549]	[810,688,832,732]	5	hSpCas9	negative selection	8887096
42272174	42272197	8	+	27260156	SU8686	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.37290084620303365	[152]	[196,199,124,271]	6	hSpCas9	negative selection	8944087
42288677	42288700	8	+	27260156	SU8686	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.030885369988699285	[215]	[192,224,221,238]	0	hSpCas9	negative selection	8944088
42290252	42290275	8	-	27260156	SU8686	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5894433272761375	[1156]	[1488,1585,1786,2143]	8	hSpCas9	negative selection	8944089
42290167	42290190	8	-	27260156	SU8686	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.25270398768367197	[608]	[513,494,445,578]	-4	hSpCas9	negative selection	9008345
42272190	42272213	8	-	27260156	SU8686	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.12214918635043981	[946]	[626,797,896,1215]	-2	hSpCas9	negative selection	9008346
42288714	42288737	8	-	27260156	SU8686	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.26562768774640855	[549]	[495,566,816,793]	4	hSpCas9	negative selection	9008347
42272174	42272197	8	+	27260156	SKES1	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.44296985805583633	[152]	[244,241,133,215]	8	hSpCas9	negative selection	9065338
42288677	42288700	8	+	27260156	SKES1	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.16611961242460427	[215]	[189,213,154,207]	-4	hSpCas9	negative selection	9065339
42290252	42290275	8	-	27260156	SKES1	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5217044983061419	[1156]	[1936,1923,1453,1399]	9	hSpCas9	negative selection	9065340
42290167	42290190	8	-	27260156	SKES1	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	0.06792226755999758	[608]	[747,703,601,523]	1	hSpCas9	negative selection	9129596
42272190	42272213	8	-	27260156	SKES1	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.006158509174549742	[946]	[1114,903,907,855]	0	hSpCas9	negative selection	9129597
42288714	42288737	8	-	27260156	SKES1	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.10969813062222636	[549]	[592,796,573,440]	2	hSpCas9	negative selection	9129598
42272174	42272197	8	+	27260156	TOV112D	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	-0.14906667148947883	[152]	[97,164,126,164]	-3	hSpCas9	negative selection	9186589
42288677	42288700	8	+	27260156	TOV112D	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	0.4152578698688766	[215]	[292,259,201,388]	7	hSpCas9	negative selection	9186590
42290252	42290275	8	-	27260156	TOV112D	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.5950204315802381	[1156]	[1230,2395,1784,1702]	9	hSpCas9	negative selection	9186591
42290167	42290190	8	-	27260156	TOV112D	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.036008374748491834	[608]	[594,618,481,685]	0	hSpCas9	negative selection	9250847
42272190	42272213	8	-	27260156	TOV112D	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.0073590368803448936	[946]	[887,1039,1035,865]	0	hSpCas9	negative selection	9250848
42288714	42288737	8	-	27260156	TOV112D	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.053964459863641207	[549]	[852,605,304,554]	1	hSpCas9	negative selection	9250849
42272174	42272197	8	+	27260156	TC71	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	0.4950796956145773	[152]	[289,220,230,177]	9	hSpCas9	negative selection	9307840
42288677	42288700	8	+	27260156	TC71	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.08320490132698533	[215]	[251,192,177,253]	-2	hSpCas9	negative selection	9307841
42290252	42290275	8	-	27260156	TC71	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.49193213445486417	[1156]	[1780,1851,1556,1794]	9	hSpCas9	negative selection	9307842
42290167	42290190	8	-	27260156	TC71	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.07325724038701537	[608]	[523,666,505,801]	-2	hSpCas9	negative selection	9372098
42272190	42272213	8	-	27260156	TC71	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	0.11985558910216065	[946]	[1251,960,1193,991]	3	hSpCas9	negative selection	9372099
42288714	42288737	8	-	27260156	TC71	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	-0.01340018952229402	[549]	[601,548,624,556]	0	hSpCas9	negative selection	9372100
42272174	42272197	8	+	27260156	TC32	viability	GATTTGGAAATGTCATCCGATGG	IKBKB	ENSG00000104365	-0.508296208829407	[152]	[49,91,130,142]	-7	hSpCas9	negative selection	9429091
42288677	42288700	8	+	27260156	TC32	viability	TCAGCCCCCGGAACCGAGAGCGG	IKBKB	ENSG00000104365	-0.22065717495845072	[215]	[174,98,286,173]	-4	hSpCas9	negative selection	9429092
42290252	42290275	8	-	27260156	TC32	viability	CCTTCCGGAGATCTCCTCCTTGG	IKBKB	ENSG00000104365	0.16869731934909526	[1156]	[1275,1008,1547,1101]	3	hSpCas9	negative selection	9429093
42290167	42290190	8	-	27260156	TC32	viability	ATCTCGGGCAGCCACCACATTGG	IKBKB	ENSG00000104365	-0.40838530395071637	[608]	[421,180,661,581]	-6	hSpCas9	negative selection	9493349
42272190	42272213	8	-	27260156	TC32	viability	GGCCTACCTGATTGTGCCATCGG	IKBKB	ENSG00000104365	-0.18612022264214823	[946]	[946,551,781,869]	-3	hSpCas9	negative selection	9493350
42288714	42288737	8	-	27260156	TC32	viability	GCCCTCACCTTCTCATGATCTGG	IKBKB	ENSG00000104365	0.07993098715125554	[549]	[387,450,730,678]	1	hSpCas9	negative selection	9493351
42271452	42271475	8	-	27869803	HPAFII	viability after 27 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.3103337419591096	[227]	[110,179,NaN]	2	hSpCas9	negative selection	9602706
42272152	42272175	8	+	27869803	HPAFII	viability after 27 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.1315051939239401	[193]	[138,88,NaN]	1	hSpCas9	negative selection	9602707
42288681	42288704	8	-	27869803	HPAFII	viability after 27 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-3.2524687643403163	[116]	[12,0,NaN]	-9	hSpCas9	negative selection	9602708
42290252	42290275	8	+	27869803	HPAFII	viability after 27 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.7555385119212898	[185]	[127,195,NaN]	6	hSpCas9	negative selection	9602709
42293461	42293484	8	+	27869803	HPAFII	viability after 27 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.605313326202615	[140]	[69,30,NaN]	-4	hSpCas9	negative selection	9602710
42305253	42305276	8	+	27869803	HPAFII	viability after 27 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.14872291293749407	[599]	[385,199,NaN]	-1	hSpCas9	negative selection	9602711
42271452	42271475	8	-	27869803	HPAFII	viability after 15 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.49463699776261183	[227]	[528,230,NaN]	5	hSpCas9	negative selection	9685155
42272152	42272175	8	+	27869803	HPAFII	viability after 15 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.2373419798484265	[193]	[394,152,NaN]	2	hSpCas9	negative selection	9685156
42288681	42288704	8	-	27869803	HPAFII	viability after 15 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.42417689129316694	[116]	[44,123,NaN]	-5	hSpCas9	negative selection	9685157
42290252	42290275	8	+	27869803	HPAFII	viability after 15 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.7651478796576286	[185]	[393,305,NaN]	8	hSpCas9	negative selection	9685158
42293461	42293484	8	+	27869803	HPAFII	viability after 15 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	0.2602720141735859	[140]	[318,95,NaN]	3	hSpCas9	negative selection	9685159
42305253	42305276	8	+	27869803	HPAFII	viability after 15 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.00843703944812968	[599]	[1033,408,NaN]	0	hSpCas9	negative selection	9685160
42271452	42271475	8	-	27869803	ASPC1	viability after 36 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.47477174003464706	[906]	[764,219,381]	5	hSpCas9	negative selection	9767604
42272152	42272175	8	+	27869803	ASPC1	viability after 36 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.6890386798515177	[402]	[684,62,32]	6	hSpCas9	negative selection	9767605
42288681	42288704	8	-	27869803	ASPC1	viability after 36 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-1.8779804107941915	[440]	[31,93,6]	-9	hSpCas9	negative selection	9767606
42290252	42290275	8	+	27869803	ASPC1	viability after 36 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-1.0467410533157868	[469]	[78,77,79]	-7	hSpCas9	negative selection	9767607
42293461	42293484	8	+	27869803	ASPC1	viability after 36 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	1.6441271420258832	[289]	[199,727,67]	9	hSpCas9	negative selection	9767608
42305253	42305276	8	+	27869803	ASPC1	viability after 36 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	0.5254462895279691	[1093]	[569,518,553]	5	hSpCas9	negative selection	9767609
42271452	42271475	8	-	27869803	PATU8988S	viability after 35 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.1790942412531248	[798]	[508,218,NaN]	2	hSpCas9	negative selection	9850053
42272152	42272175	8	+	27869803	PATU8988S	viability after 35 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.6805773188802955	[536]	[107,161,NaN]	-6	hSpCas9	negative selection	9850054
42288681	42288704	8	-	27869803	PATU8988S	viability after 35 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.5352475382149284	[238]	[31,100,NaN]	-5	hSpCas9	negative selection	9850055
42290252	42290275	8	+	27869803	PATU8988S	viability after 35 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	0.6269392052409588	[292]	[65,298,NaN]	7	hSpCas9	negative selection	9850056
42293461	42293484	8	+	27869803	PATU8988S	viability after 35 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.050169652813188415	[377]	[162,130,NaN]	0	hSpCas9	negative selection	9850057
42305253	42305276	8	+	27869803	PATU8988S	viability after 35 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.14011767674416875	[972]	[401,308,NaN]	-1	hSpCas9	negative selection	9850058
42271452	42271475	8	-	27869803	PATU8988S	viability after 31 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	0.11935570621500824	[798]	[320,377,NaN]	1	hSpCas9	negative selection	9932502
42272152	42272175	8	+	27869803	PATU8988S	viability after 31 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	-0.6805985556607649	[536]	[104,169,NaN]	-6	hSpCas9	negative selection	9932503
42288681	42288704	8	-	27869803	PATU8988S	viability after 31 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-0.3959126015850081	[238]	[16,142,NaN]	-4	hSpCas9	negative selection	9932504
42290252	42290275	8	+	27869803	PATU8988S	viability after 31 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	-0.07192993970755779	[292]	[60,174,NaN]	-1	hSpCas9	negative selection	9932505
42293461	42293484	8	+	27869803	PATU8988S	viability after 31 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.20805726094318933	[377]	[144,111,NaN]	-2	hSpCas9	negative selection	9932506
42305253	42305276	8	+	27869803	PATU8988S	viability after 31 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.26556312009815086	[972]	[265,394,NaN]	-3	hSpCas9	negative selection	9932507
42271452	42271475	8	-	27869803	HPAFII	viability after 35 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.5207703132668584	[227]	[39,125,NaN]	-3	hSpCas9	negative selection	10014951
42272152	42272175	8	+	27869803	HPAFII	viability after 35 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.03280179056228716	[193]	[99,100,NaN]	0	hSpCas9	negative selection	10014952
42288681	42288704	8	-	27869803	HPAFII	viability after 35 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-5.88827616658673	[116]	[0,0,NaN]	-9	hSpCas9	negative selection	10014953
42290252	42290275	8	+	27869803	HPAFII	viability after 35 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	1.3315526829871978	[185]	[196,281,NaN]	8	hSpCas9	negative selection	10014954
42293461	42293484	8	+	27869803	HPAFII	viability after 35 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.09623303840682107	[140]	[86,43,NaN]	0	hSpCas9	negative selection	10014955
42305253	42305276	8	+	27869803	HPAFII	viability after 35 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.18994786295983546	[599]	[349,171,NaN]	-1	hSpCas9	negative selection	10014956
42271452	42271475	8	-	27869803	HPAFII	viability after 31 days	CTCACCTGTCGGCAGGGACGCGG	IKBKB	ENSG00000104365	-0.2566079296783478	[227]	[75,140,NaN]	-2	hSpCas9	negative selection	10097400
42272152	42272175	8	+	27869803	HPAFII	viability after 31 days	AAAGAGCGCCTTGGGACAGGGGG	IKBKB	ENSG00000104365	0.011441589074228764	[193]	[103,115,NaN]	0	hSpCas9	negative selection	10097401
42288681	42288704	8	-	27869803	HPAFII	viability after 31 days	ACCACCGCTCTCGGTTCCGGGGG	IKBKB	ENSG00000104365	-2.7347789325950624	[116]	[17,0,NaN]	-8	hSpCas9	negative selection	10097402
42290252	42290275	8	+	27869803	HPAFII	viability after 31 days	CCAAGGAGGAGATCTCCGGAAGG	IKBKB	ENSG00000104365	1.0663619793517687	[185]	[164,276,NaN]	7	hSpCas9	negative selection	10097403
42293461	42293484	8	+	27869803	HPAFII	viability after 31 days	AACTGCTGTGGTCTGCGGGAAGG	IKBKB	ENSG00000104365	-0.5425409460379113	[140]	[83,21,NaN]	-4	hSpCas9	negative selection	10097404
42305253	42305276	8	+	27869803	HPAFII	viability after 31 days	TCCTGCAGCAAGGAGAACAGAGG	IKBKB	ENSG00000104365	-0.20947478563181665	[599]	[351,224,NaN]	-1	hSpCas9	negative selection	10097405
42290162	42290185	8	-	28162770	P31FUJ	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	0.17566264094097872	[54]	[72]	1	hSpCas9	negative selection	10173650
42316790	42316813	8	+	28162770	P31FUJ	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.4424157036431058	[505]	[807]	5	hSpCas9	negative selection	10173651
42308999	42309022	8	-	28162770	P31FUJ	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-0.34469508448527575	[133]	[123]	-3	hSpCas9	negative selection	10173652
42314331	42314354	8	+	28162770	P31FUJ	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.7397621931342615	[134]	[94]	-5	hSpCas9	negative selection	10173653
42316805	42316828	8	+	28162770	P31FUJ	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-3.6251196271931385	[20]	[1]	-9	hSpCas9	negative selection	10173654
42319610	42319633	8	+	28162770	P31FUJ	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-1.7717784998613548	[246]	[84]	-8	hSpCas9	negative selection	10173655
42326055	42326078	8	-	28162770	P31FUJ	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	0.4573886306468464	[162]	[262]	5	hSpCas9	negative selection	10173656
42290178	42290201	8	+	28162770	P31FUJ	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.717321888946052	[823]	[1591]	7	hSpCas9	negative selection	10173657
42293449	42293472	8	+	28162770	P31FUJ	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.7148957939156984	[322]	[622]	7	hSpCas9	negative selection	10173658
42305187	42305210	8	-	28162770	P31FUJ	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.019898971782058905	[396]	[472]	0	hSpCas9	negative selection	10173659
42290162	42290185	8	-	28162770	TF1	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	NaN	[NaN]	[9]	1	hSpCas9	negative selection	10343016
42316790	42316813	8	+	28162770	TF1	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	NaN	[NaN]	[713]	1	hSpCas9	negative selection	10343017
42308999	42309022	8	-	28162770	TF1	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10343018
42314331	42314354	8	+	28162770	TF1	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10343019
42316805	42316828	8	+	28162770	TF1	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10343020
42319610	42319633	8	+	28162770	TF1	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	NaN	[NaN]	[89]	1	hSpCas9	negative selection	10343021
42326055	42326078	8	-	28162770	TF1	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	NaN	[NaN]	[372]	1	hSpCas9	negative selection	10343022
42290178	42290201	8	+	28162770	TF1	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	NaN	[NaN]	[1122]	1	hSpCas9	negative selection	10343023
42293449	42293472	8	+	28162770	TF1	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	NaN	[NaN]	[543]	1	hSpCas9	negative selection	10343024
42305187	42305210	8	-	28162770	TF1	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	NaN	[NaN]	[497]	1	hSpCas9	negative selection	10343025
42290162	42290185	8	-	28162770	SKM1	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.5809935985182104	[21]	[12]	-8	hSpCas9	negative selection	10512382
42316790	42316813	8	+	28162770	SKM1	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.1653982651983612	[114]	[227]	1	hSpCas9	negative selection	10512383
42308999	42309022	8	-	28162770	SKM1	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	0.6024961305059044	[37]	[101]	6	hSpCas9	negative selection	10512384
42314331	42314354	8	+	28162770	SKM1	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.7170321384204629	[52]	[56]	-5	hSpCas9	negative selection	10512385
42316805	42316828	8	+	28162770	SKM1	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-2.991926699464318	[8]	[1]	-9	hSpCas9	negative selection	10512386
42319610	42319633	8	+	28162770	SKM1	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.08503610385579949	[68]	[114]	0	hSpCas9	negative selection	10512387
42326055	42326078	8	-	28162770	SKM1	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	1.2085866218114174	[34]	[142]	9	hSpCas9	negative selection	10512388
42290178	42290201	8	+	28162770	SKM1	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.469552747821838	[191]	[469]	4	hSpCas9	negative selection	10512389
42293449	42293472	8	+	28162770	SKM1	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.0933860742630529	[78]	[148]	0	hSpCas9	negative selection	10512390
42305187	42305210	8	-	28162770	SKM1	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.3631097072349829	[83]	[190]	3	hSpCas9	negative selection	10512391
42290162	42290185	8	-	28162770	SKM1	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.5809935985182104	[21]	[12]	-8	hSpCas9	negative selection	10681748
42316790	42316813	8	+	28162770	SKM1	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.1653982651983612	[114]	[227]	1	hSpCas9	negative selection	10681749
42308999	42309022	8	-	28162770	SKM1	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	0.6024961305059044	[37]	[101]	6	hSpCas9	negative selection	10681750
42314331	42314354	8	+	28162770	SKM1	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.7170321384204629	[52]	[56]	-5	hSpCas9	negative selection	10681751
42316805	42316828	8	+	28162770	SKM1	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-2.991926699464318	[8]	[1]	-9	hSpCas9	negative selection	10681752
42319610	42319633	8	+	28162770	SKM1	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.08503610385579949	[68]	[114]	0	hSpCas9	negative selection	10681753
42326055	42326078	8	-	28162770	SKM1	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	1.2085866218114174	[34]	[142]	9	hSpCas9	negative selection	10681754
42290178	42290201	8	+	28162770	SKM1	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.469552747821838	[191]	[469]	4	hSpCas9	negative selection	10681755
42293449	42293472	8	+	28162770	SKM1	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.0933860742630529	[78]	[148]	0	hSpCas9	negative selection	10681756
42305187	42305210	8	-	28162770	SKM1	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.3631097072349829	[83]	[190]	3	hSpCas9	negative selection	10681757
42290162	42290185	8	-	28162770	PL21	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.3848228862318361	[59]	[9]	-7	hSpCas9	negative selection	10851114
42316790	42316813	8	+	28162770	PL21	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	-0.02621082041581113	[364]	[155]	0	hSpCas9	negative selection	10851115
42308999	42309022	8	-	28162770	PL21	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	0.31216623222343165	[160]	[86]	2	hSpCas9	negative selection	10851116
42314331	42314354	8	+	28162770	PL21	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-1.4354489593018043	[173]	[27]	-7	hSpCas9	negative selection	10851117
42316805	42316828	8	+	28162770	PL21	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	0.5900861328053337	[28]	[18]	5	hSpCas9	negative selection	10851118
42319610	42319633	8	+	28162770	PL21	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.4726184907268498	[270]	[84]	-3	hSpCas9	negative selection	10851119
42326055	42326078	8	-	28162770	PL21	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	0.5114984676664952	[136]	[84]	4	hSpCas9	negative selection	10851120
42290178	42290201	8	+	28162770	PL21	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.6132393095266717	[744]	[495]	5	hSpCas9	negative selection	10851121
42293449	42293472	8	+	28162770	PL21	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.7147127873190783	[244]	[174]	6	hSpCas9	negative selection	10851122
42305187	42305210	8	-	28162770	PL21	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.4306234481793158	[253]	[148]	4	hSpCas9	negative selection	10851123
42290162	42290185	8	-	28162770	P31FUJ	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	0.17566264094097872	[54]	[72]	1	hSpCas9	negative selection	11020480
42316790	42316813	8	+	28162770	P31FUJ	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.4424157036431058	[505]	[807]	5	hSpCas9	negative selection	11020481
42308999	42309022	8	-	28162770	P31FUJ	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-0.34469508448527575	[133]	[123]	-3	hSpCas9	negative selection	11020482
42314331	42314354	8	+	28162770	P31FUJ	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.7397621931342615	[134]	[94]	-5	hSpCas9	negative selection	11020483
42316805	42316828	8	+	28162770	P31FUJ	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-3.6251196271931385	[20]	[1]	-9	hSpCas9	negative selection	11020484
42319610	42319633	8	+	28162770	P31FUJ	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-1.7717784998613548	[246]	[84]	-8	hSpCas9	negative selection	11020485
42326055	42326078	8	-	28162770	P31FUJ	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	0.4573886306468464	[162]	[262]	5	hSpCas9	negative selection	11020486
42290178	42290201	8	+	28162770	P31FUJ	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.717321888946052	[823]	[1591]	7	hSpCas9	negative selection	11020487
42293449	42293472	8	+	28162770	P31FUJ	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.7148957939156984	[322]	[622]	7	hSpCas9	negative selection	11020488
42305187	42305210	8	-	28162770	P31FUJ	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.019898971782058905	[396]	[472]	0	hSpCas9	negative selection	11020489
42290162	42290185	8	-	28162770	OCIAML5	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-4.2096185754820805	[40]	[3]	-9	hSpCas9	negative selection	11189846
42316790	42316813	8	+	28162770	OCIAML5	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	-0.49627967196059863	[378]	[484]	-3	hSpCas9	negative selection	11189847
42308999	42309022	8	-	28162770	OCIAML5	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	0.9427430978744936	[65]	[228]	7	hSpCas9	negative selection	11189848
42314331	42314354	8	+	28162770	OCIAML5	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-1.44930740136359	[58]	[38]	-7	hSpCas9	negative selection	11189849
42316805	42316828	8	+	28162770	OCIAML5	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-5.173994665751359	[19]	[0]	-9	hSpCas9	negative selection	11189850
42319610	42319633	8	+	28162770	OCIAML5	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-1.1665771941888763	[96]	[77]	-6	hSpCas9	negative selection	11189851
42326055	42326078	8	-	28162770	OCIAML5	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	0.3747042909830253	[93]	[219]	3	hSpCas9	negative selection	11189852
42290178	42290201	8	+	28162770	OCIAML5	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.14793342913600283	[454]	[909]	1	hSpCas9	negative selection	11189853
42293449	42293472	8	+	28162770	OCIAML5	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	1.2323979422391238	[169]	[720]	9	hSpCas9	negative selection	11189854
42305187	42305210	8	-	28162770	OCIAML5	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.3023795448903712	[206]	[302]	-2	hSpCas9	negative selection	11189855
42290162	42290185	8	-	28162770	EOL1	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-0.7510172779315281	[114]	[35]	-5	hSpCas9	negative selection	11359212
42316790	42316813	8	+	28162770	EOL1	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.7857837016146829	[457]	[415]	7	hSpCas9	negative selection	11359213
42308999	42309022	8	-	28162770	EOL1	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-1.263079231605237	[245]	[53]	-7	hSpCas9	negative selection	11359214
42314331	42314354	8	+	28162770	EOL1	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-1.042285364494266	[300]	[76]	-6	hSpCas9	negative selection	11359215
42316805	42316828	8	+	28162770	EOL1	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-3.7758919465705576	[51]	[1]	-9	hSpCas9	negative selection	11359216
42319610	42319633	8	+	28162770	EOL1	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-1.5348838470667627	[516]	[93]	-7	hSpCas9	negative selection	11359217
42326055	42326078	8	-	28162770	EOL1	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	0.16270750876529894	[194]	[114]	1	hSpCas9	negative selection	11359218
42290178	42290201	8	+	28162770	EOL1	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.6147386066317595	[977]	[788]	5	hSpCas9	negative selection	11359219
42293449	42293472	8	+	28162770	EOL1	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	-0.23381782409805488	[403]	[180]	-2	hSpCas9	negative selection	11359220
42305187	42305210	8	-	28162770	EOL1	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.054058504566938836	[361]	[197]	0	hSpCas9	negative selection	11359221
42290162	42290185	8	-	28162770	MOLM13	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.4390012140639399	[74]	[19]	-6	hSpCas9	negative selection	11528578
42316790	42316813	8	+	28162770	MOLM13	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	1.0536967988584873	[568]	[853]	7	hSpCas9	negative selection	11528579
42308999	42309022	8	-	28162770	MOLM13	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-0.5551942315684624	[188]	[92]	-3	hSpCas9	negative selection	11528580
42314331	42314354	8	+	28162770	MOLM13	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-1.684113711900471	[199]	[44]	-7	hSpCas9	negative selection	11528581
42316805	42316828	8	+	28162770	MOLM13	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-5.260031073018621	[52]	[0]	-9	hSpCas9	negative selection	11528582
42319610	42319633	8	+	28162770	MOLM13	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-3.9312817122752444	[421]	[19]	-9	hSpCas9	negative selection	11528583
42326055	42326078	8	-	28162770	MOLM13	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	0.6649262286041324	[163]	[187]	5	hSpCas9	negative selection	11528584
42290178	42290201	8	+	28162770	MOLM13	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	-0.7876113516038077	[1145]	[479]	-4	hSpCas9	negative selection	11528585
42293449	42293472	8	+	28162770	MOLM13	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.12119704666387543	[425]	[334]	0	hSpCas9	negative selection	11528586
42305187	42305210	8	-	28162770	MOLM13	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.4638082047327617	[353]	[352]	3	hSpCas9	negative selection	11528587
42290162	42290185	8	-	28162770	HEL	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.2052580745545929	[89]	[24]	-6	hSpCas9	negative selection	11697944
42316790	42316813	8	+	28162770	HEL	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.5323927226835715	[420]	[389]	4	hSpCas9	negative selection	11697945
42308999	42309022	8	-	28162770	HEL	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	0.7076942738411268	[151]	[158]	6	hSpCas9	negative selection	11697946
42314331	42314354	8	+	28162770	HEL	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.735772791253373	[181]	[69]	-5	hSpCas9	negative selection	11697947
42316805	42316828	8	+	28162770	HEL	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-3.9422236687207994	[23]	[0]	-9	hSpCas9	negative selection	11697948
42319610	42319633	8	+	28162770	HEL	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.6133236132257273	[288]	[120]	-4	hSpCas9	negative selection	11697949
42326055	42326078	8	-	28162770	HEL	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	-0.12664823985822682	[149]	[87]	-1	hSpCas9	negative selection	11697950
42290178	42290201	8	+	28162770	HEL	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.386247272033335	[791]	[662]	3	hSpCas9	negative selection	11697951
42293449	42293472	8	+	28162770	HEL	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.8870946848093757	[297]	[352]	7	hSpCas9	negative selection	11697952
42305187	42305210	8	-	28162770	HEL	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.4171791315852258	[379]	[324]	3	hSpCas9	negative selection	11697953
42290162	42290185	8	-	28162770	MV411	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.3051034722460038	[87]	[29]	-7	hSpCas9	negative selection	11867310
42316790	42316813	8	+	28162770	MV411	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.26513955251623433	[323]	[327]	2	hSpCas9	negative selection	11867311
42308999	42309022	8	-	28162770	MV411	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-1.1899677615245228	[129]	[47]	-7	hSpCas9	negative selection	11867312
42314331	42314354	8	+	28162770	MV411	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-1.7628307846710518	[140]	[34]	-8	hSpCas9	negative selection	11867313
42316805	42316828	8	+	28162770	MV411	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-0.33752494993838056	[32]	[21]	-3	hSpCas9	negative selection	11867314
42319610	42319633	8	+	28162770	MV411	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.7044681610161796	[235]	[121]	-5	hSpCas9	negative selection	11867315
42326055	42326078	8	-	28162770	MV411	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	1.7749977404590092	[93]	[270]	9	hSpCas9	negative selection	11867316
42290178	42290201	8	+	28162770	MV411	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	-0.1613318935636352	[688]	[518]	-1	hSpCas9	negative selection	11867317
42293449	42293472	8	+	28162770	MV411	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.8791538202036733	[252]	[391]	7	hSpCas9	negative selection	11867318
42305187	42305210	8	-	28162770	MV411	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.15998676438619341	[251]	[189]	-1	hSpCas9	negative selection	11867319
42290162	42290185	8	-	28162770	MONOMAC1	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.5380737648946208	[37]	[14]	-8	hSpCas9	negative selection	12036676
42316790	42316813	8	+	28162770	MONOMAC1	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.6040043010658481	[228]	[398]	6	hSpCas9	negative selection	12036677
42308999	42309022	8	-	28162770	MONOMAC1	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-0.07674261334184174	[91]	[99]	0	hSpCas9	negative selection	12036678
42314331	42314354	8	+	28162770	MONOMAC1	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-0.07674261334184192	[114]	[124]	0	hSpCas9	negative selection	12036679
42316805	42316828	8	+	28162770	MONOMAC1	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-4.589354269838314	[20]	[0]	-9	hSpCas9	negative selection	12036680
42319610	42319633	8	+	28162770	MONOMAC1	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.5608490229832244	[165]	[128]	-5	hSpCas9	negative selection	12036681
42326055	42326078	8	-	28162770	MONOMAC1	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	2.0393398037125956	[65]	[310]	9	hSpCas9	negative selection	12036682
42290178	42290201	8	+	28162770	MONOMAC1	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	1.1096244911744981	[398]	[986]	8	hSpCas9	negative selection	12036683
42293449	42293472	8	+	28162770	MONOMAC1	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	0.7293820205593391	[180]	[343]	7	hSpCas9	negative selection	12036684
42305187	42305210	8	-	28162770	MONOMAC1	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	0.18596682457957692	[147]	[192]	2	hSpCas9	negative selection	12036685
42290162	42290185	8	-	28162770	OCIAML2	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-2.6930222465786096	[6]	[5]	-9	hSpCas9	negative selection	12206042
42316790	42316813	8	+	28162770	OCIAML2	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.7220152527002347	[48]	[447]	7	hSpCas9	negative selection	12206043
42308999	42309022	8	-	28162770	OCIAML2	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-0.23541336354812958	[23]	[112]	-2	hSpCas9	negative selection	12206044
42314331	42314354	8	+	28162770	OCIAML2	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	-1.4489347541428423	[32]	[66]	-7	hSpCas9	negative selection	12206045
42316805	42316828	8	+	28162770	OCIAML2	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-6.171069543383254	[12]	[0]	-9	hSpCas9	negative selection	12206046
42319610	42319633	8	+	28162770	OCIAML2	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-1.252206306108659	[51]	[120]	-7	hSpCas9	negative selection	12206047
42326055	42326078	8	-	28162770	OCIAML2	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	-0.004311821019624129	[18]	[104]	0	hSpCas9	negative selection	12206048
42290178	42290201	8	+	28162770	OCIAML2	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	-0.36391748922177025	[126]	[546]	-3	hSpCas9	negative selection	12206049
42293449	42293472	8	+	28162770	OCIAML2	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	1.031870515287022	[32]	[373]	8	hSpCas9	negative selection	12206050
42305187	42305210	8	-	28162770	OCIAML2	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.22465058358809742	[38]	[184]	-2	hSpCas9	negative selection	12206051
42290162	42290185	8	-	28162770	OCIAML3	viability	GGGCAGCCACCACATTGGGGTGG	IKBKB	ENSG00000104365	-1.4013625623817674	[20]	[23]	-7	hSpCas9	negative selection	12375408
42316790	42316813	8	+	28162770	OCIAML3	viability	GGCCAGAATCCAACAGGACACGG	IKBKB	ENSG00000104365	0.8037953215383268	[99]	[526]	7	hSpCas9	negative selection	12375409
42308999	42309022	8	-	28162770	OCIAML3	viability	GCACGGGCTGCCAGTTGGGGAGG	IKBKB	ENSG00000104365	-1.4988504072838231	[43]	[46]	-7	hSpCas9	negative selection	12375410
42314331	42314354	8	+	28162770	OCIAML3	viability	AGTGCGGCAGAAGAGTGAGGTGG	IKBKB	ENSG00000104365	0.7279204545631992	[28]	[144]	6	hSpCas9	negative selection	12375411
42316805	42316828	8	+	28162770	OCIAML3	viability	GGACACGGGCATCCCAGAGGAGG	IKBKB	ENSG00000104365	-0.12007645199175077	[8]	[24]	-1	hSpCas9	negative selection	12375412
42319610	42319633	8	+	28162770	OCIAML3	viability	GAGGGAAATGGAGCAGGCTGTGG	IKBKB	ENSG00000104365	-0.33850690717577686	[79]	[190]	-3	hSpCas9	negative selection	12375413
42326055	42326078	8	-	28162770	OCIAML3	viability	TAAGCTGTTGGAGGCCGTGGAGG	IKBKB	ENSG00000104365	-1.5284192986965865	[42]	[44]	-8	hSpCas9	negative selection	12375414
42290178	42290201	8	+	28162770	OCIAML3	viability	GCTGCCCGAGATGTCCCTGAGGG	IKBKB	ENSG00000104365	0.5686125604949157	[175]	[787]	5	hSpCas9	negative selection	12375415
42293449	42293472	8	+	28162770	OCIAML3	viability	AACCAGTTTGAGAACTGCTGTGG	IKBKB	ENSG00000104365	-0.19947579647996072	[61]	[162]	-1	hSpCas9	negative selection	12375416
42305187	42305210	8	-	28162770	OCIAML3	viability	ATGAAGGTATCTAAGCGCAGAGG	IKBKB	ENSG00000104365	-0.15472259479864206	[58]	[159]	-1	hSpCas9	negative selection	12375417