Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3554
• Symbol:IL1R1
• Description:interleukin 1 receptor type 1

DataSource: http://genomecrispr.dkfz.de/#!/results/IL1R1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
102168629	102168652	2	+	26472758	Jiyoye	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.3850364042366249	[196]	[193]	3	hSpCas9	negative selection	77489
102166179	102166202	2	+	26472758	Jiyoye	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	-0.0498102997709412	[220]	[160]	0	hSpCas9	negative selection	77490
102168595	102168618	2	+	26472758	Jiyoye	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.6757908196029669	[214]	[258]	5	hSpCas9	negative selection	77491
102164924	102164947	2	-	26472758	Jiyoye	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.9877192109600247	[108]	[162]	6	hSpCas9	negative selection	77492
102164958	102164981	2	+	26472758	Jiyoye	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.46480219908792897	[318]	[331]	3	hSpCas9	negative selection	77493
102165209	102165232	2	+	26472758	Jiyoye	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	-0.524293236823311	[184]	[96]	-4	hSpCas9	negative selection	77494
102168642	102168665	2	+	26472758	Jiyoye	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	-0.608421473545145	[92]	[45]	-4	hSpCas9	negative selection	77495
102171893	102171916	2	-	26472758	Jiyoye	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	0.3439815550186795	[69]	[66]	2	hSpCas9	negative selection	77496
102168629	102168652	2	+	26472758	KBM7	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.31680182513192456	[824,808]	[511,451]	3	hSpCas9	negative selection	268607
102166179	102166202	2	+	26472758	KBM7	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.5855528682367738	[779,461]	[639,239]	6	hSpCas9	negative selection	268608
102168595	102168618	2	+	26472758	KBM7	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.6895929944529957	[847,430]	[628,329]	7	hSpCas9	negative selection	268609
102164924	102164947	2	-	26472758	KBM7	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	-0.2132068518895349	[681,437]	[200,242]	-2	hSpCas9	negative selection	268610
102164958	102164981	2	+	26472758	KBM7	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.3140487587044891	[1681,2044]	[1323,909]	3	hSpCas9	negative selection	268611
102165209	102165232	2	+	26472758	KBM7	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	-0.11141005017314999	[600,505]	[183,289]	-1	hSpCas9	negative selection	268612
102168642	102168665	2	+	26472758	KBM7	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	-0.610215653926435	[316,352]	[89,116]	-5	hSpCas9	negative selection	268613
102171893	102171916	2	-	26472758	KBM7	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-0.13276785797432766	[194,166]	[88,66]	-1	hSpCas9	negative selection	268614
102168629	102168652	2	+	26472758	Raji	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.0036477770151442934	[431]	[99]	0	hSpCas9	negative selection	459725
102166179	102166202	2	+	26472758	Raji	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	1.1431335603228012	[278]	[142]	8	hSpCas9	negative selection	459726
102168595	102168618	2	+	26472758	Raji	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.9049457204127966	[358]	[155]	8	hSpCas9	negative selection	459727
102164924	102164947	2	-	26472758	Raji	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	-0.10516110000650128	[291]	[62]	-1	hSpCas9	negative selection	459728
102164958	102164981	2	+	26472758	Raji	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.08708397376306909	[1001]	[246]	0	hSpCas9	negative selection	459729
102165209	102165232	2	+	26472758	Raji	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	-0.02898890635768639	[254]	[57]	0	hSpCas9	negative selection	459730
102168642	102168665	2	+	26472758	Raji	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	-0.433184845989103	[127]	[21]	-4	hSpCas9	negative selection	459731
102171893	102171916	2	-	26472758	Raji	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-1.021899481571367	[104]	[11]	-6	hSpCas9	negative selection	459732
102168629	102168652	2	+	26472758	K562	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.9985417039563196	[768]	[1296]	8	hSpCas9	negative selection	650843
102166179	102166202	2	+	26472758	K562	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	-0.7145053293306375	[553]	[284]	-4	hSpCas9	negative selection	650844
102168595	102168618	2	+	26472758	K562	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.5683217647388669	[583]	[730]	4	hSpCas9	negative selection	650845
102164924	102164947	2	-	26472758	K562	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.30946225957232687	[411]	[430]	2	hSpCas9	negative selection	650846
102164958	102164981	2	+	26472758	K562	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.5997772004550168	[1492]	[1909]	5	hSpCas9	negative selection	650847
102165209	102165232	2	+	26472758	K562	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.4734772477765262	[400]	[469]	4	hSpCas9	negative selection	650848
102168642	102168665	2	+	26472758	K562	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.5663468225538093	[211]	[264]	4	hSpCas9	negative selection	650849
102171893	102171916	2	-	26472758	K562	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-0.6703339857150421	[114]	[60]	-4	hSpCas9	negative selection	650850
102164955	102164978	2	+	26627737	DLD1	viability	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.03478173904045595	[635]	[194,163,243]	0	hSpCas9	negative selection	808021
102165215	102165238	2	-	26627737	DLD1	viability	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.36872799889835617	[187]	[67,54,99]	4	hSpCas9	negative selection	808022
102165216	102165239	2	-	26627737	DLD1	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	1.1533205419182706	[195]	[92,228,96]	9	hSpCas9	negative selection	808023
102168629	102168652	2	+	26627737	DLD1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.41679938299643116	[408]	[170,210,136]	4	hSpCas9	negative selection	808024
102164955	102164978	2	+	26627737	GBM cells	viability after 5 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.19645781114608885	[357]	[238,200]	3	hSpCas9	negative selection	890336
102165215	102165238	2	-	26627737	GBM cells	viability after 5 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.47282118709784593	[130]	[92,101]	7	hSpCas9	negative selection	890337
102165216	102165239	2	-	26627737	GBM cells	viability after 5 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-1.1941955295057958	[127]	[33,25]	-9	hSpCas9	negative selection	890338
102168629	102168652	2	+	26627737	GBM cells	viability after 5 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.39002807489145497	[216]	[161,142]	6	hSpCas9	negative selection	890339
102164955	102164978	2	+	26627737	GBM cells	viability after 13 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.21977998235331375	[357]	[223,227]	3	hSpCas9	negative selection	972651
102165215	102165238	2	-	26627737	GBM cells	viability after 13 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	1.2514414165502101	[130]	[198,144]	9	hSpCas9	negative selection	972652
102165216	102165239	2	-	26627737	GBM cells	viability after 13 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.37464646072001695	[127]	[84,27]	-4	hSpCas9	negative selection	972653
102168629	102168652	2	+	26627737	GBM cells	viability after 13 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.8716528545017339	[216]	[258,179]	8	hSpCas9	negative selection	972654
102164955	102164978	2	+	26627737	GBM cells	viability after 21 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.7709257432804428	[357]	[369,296]	7	hSpCas9	negative selection	1054966
102165215	102165238	2	-	26627737	GBM cells	viability after 21 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	1.8591554884980366	[130]	[276,240]	9	hSpCas9	negative selection	1054967
102165216	102165239	2	-	26627737	GBM cells	viability after 21 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.9330196576145576	[127]	[49,23]	-7	hSpCas9	negative selection	1054968
102168629	102168652	2	+	26627737	GBM cells	viability after 21 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.2644727237510685	[216]	[277,287]	9	hSpCas9	negative selection	1054969
102164955	102164978	2	+	26627737	RPE1	viability after 9 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.2355137296027458	[1249]	[372,279]	-2	hSpCas9	negative selection	1137281
102165215	102165238	2	-	26627737	RPE1	viability after 9 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.8083224995557479	[452]	[236,262]	5	hSpCas9	negative selection	1137282
102165216	102165239	2	-	26627737	RPE1	viability after 9 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.9612908190566996	[250]	[183,112]	6	hSpCas9	negative selection	1137283
102168629	102168652	2	+	26627737	RPE1	viability after 9 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.3664595826309693	[1223]	[260,343]	-3	hSpCas9	negative selection	1137284
102164955	102164978	2	+	26627737	RPE1	viability after 12 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.06017213268006627	[1249]	[376,263]	0	hSpCas9	negative selection	1219596
102165215	102165238	2	-	26627737	RPE1	viability after 12 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.8086144476199991	[452]	[218,206]	5	hSpCas9	negative selection	1219597
102165216	102165239	2	-	26627737	RPE1	viability after 12 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.7610691254394865	[250]	[106,121]	5	hSpCas9	negative selection	1219598
102168629	102168652	2	+	26627737	RPE1	viability after 12 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.22934599659843202	[1223]	[297,261]	-1	hSpCas9	negative selection	1219599
102164955	102164978	2	+	26627737	RPE1	viability after 15 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.3778225745479984	[1249]	[489,429]	2	hSpCas9	negative selection	1301911
102165215	102165238	2	-	26627737	RPE1	viability after 15 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.6769220276502819	[452]	[127,278]	4	hSpCas9	negative selection	1301912
102165216	102165239	2	-	26627737	RPE1	viability after 15 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.7690146055104061	[250]	[64,174]	5	hSpCas9	negative selection	1301913
102168629	102168652	2	+	26627737	RPE1	viability after 15 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.20029614036300847	[1223]	[252,347]	-1	hSpCas9	negative selection	1301914
102164955	102164978	2	+	26627737	RPE1	viability after 18 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.03655763148982094	[1249]	[354,300]	0	hSpCas9	negative selection	1384226
102165215	102165238	2	-	26627737	RPE1	viability after 18 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.9200909626283688	[452]	[167,298]	5	hSpCas9	negative selection	1384227
102165216	102165239	2	-	26627737	RPE1	viability after 18 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	1.6857443630483278	[250]	[127,313]	8	hSpCas9	negative selection	1384228
102168629	102168652	2	+	26627737	RPE1	viability after 18 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.0034222033477875335	[1223]	[304,358]	0	hSpCas9	negative selection	1384229
102164955	102164978	2	+	26627737	HeLa	viability after 8 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.08759341969487094	[482]	[174,255,227]	0	hSpCas9	negative selection	1466541
102165215	102165238	2	-	26627737	HeLa	viability after 8 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	-0.4784107829000799	[191]	[100,28,58]	-5	hSpCas9	negative selection	1466542
102165216	102165239	2	-	26627737	HeLa	viability after 8 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	1.1558975209122337	[123]	[120,106,131]	8	hSpCas9	negative selection	1466543
102168629	102168652	2	+	26627737	HeLa	viability after 8 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.3861906642937458	[202]	[103,229,323]	8	hSpCas9	negative selection	1466544
102164955	102164978	2	+	26627737	HeLa	viability after 12 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.32733132190396175	[482]	[226,199,328]	3	hSpCas9	negative selection	1548856
102165215	102165238	2	-	26627737	HeLa	viability after 12 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	1.067527837104208	[191]	[235,174,88]	7	hSpCas9	negative selection	1548857
102165216	102165239	2	-	26627737	HeLa	viability after 12 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.2565804517319261	[123]	[51,32,44]	-2	hSpCas9	negative selection	1548858
102168629	102168652	2	+	26627737	HeLa	viability after 12 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.2341226105105925	[202]	[199,273,109]	8	hSpCas9	negative selection	1548859
102164955	102164978	2	+	26627737	HeLa	viability after 15 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.30163576112351564	[482]	[156,197,383]	2	hSpCas9	negative selection	1631171
102165215	102165238	2	-	26627737	HeLa	viability after 15 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.23006405792778517	[191]	[101,79,92]	2	hSpCas9	negative selection	1631172
102165216	102165239	2	-	26627737	HeLa	viability after 15 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.25902489051362654	[123]	[75,56,46]	2	hSpCas9	negative selection	1631173
102168629	102168652	2	+	26627737	HeLa	viability after 15 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.37930635437330673	[202]	[124,116,77]	3	hSpCas9	negative selection	1631174
102164955	102164978	2	+	26627737	HeLa	viability after 18 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.3310161289688661	[482]	[110,168,383]	2	hSpCas9	negative selection	1713486
102165215	102165238	2	-	26627737	HeLa	viability after 18 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.23141982002950712	[191]	[67,66,92]	2	hSpCas9	negative selection	1713487
102165216	102165239	2	-	26627737	HeLa	viability after 18 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.23236426914906239	[123]	[48,46,46]	2	hSpCas9	negative selection	1713488
102168629	102168652	2	+	26627737	HeLa	viability after 18 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.4625915079013236	[202]	[92,100,77]	4	hSpCas9	negative selection	1713489
102164955	102164978	2	+	26627737	HCT116	viability after 6 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.37632955074011	[862]	[217,152]	2	hSpCas9	negative selection	1795801
102165215	102165238	2	-	26627737	HCT116	viability after 6 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	-0.4559097023447327	[414]	[131,0]	-3	hSpCas9	negative selection	1795802
102165216	102165239	2	-	26627737	HCT116	viability after 6 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.3412711542300748	[403]	[53,47]	-2	hSpCas9	negative selection	1795803
102168629	102168652	2	+	26627737	HCT116	viability after 6 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.4633682950905416	[598]	[144,25]	-3	hSpCas9	negative selection	1795804
102164955	102164978	2	+	26627737	HCT116	viability after 8 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.4278176258071763	[412]	[308,348,260]	4	hSpCas9	negative selection	1878116
102165215	102165238	2	-	26627737	HCT116	viability after 8 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.4176603357895783	[133]	[98,106,89]	4	hSpCas9	negative selection	1878117
102165216	102165239	2	-	26627737	HCT116	viability after 8 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.4514464404901447	[114]	[66,138,53]	5	hSpCas9	negative selection	1878118
102168629	102168652	2	+	26627737	HCT116	viability after 8 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.3331542804625891	[205]	[118,119,188]	3	hSpCas9	negative selection	1878119
102164955	102164978	2	+	26627737	HCT116	viability after 9 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.7367857587398905	[862]	[230,64]	-5	hSpCas9	negative selection	1960431
102165215	102165238	2	-	26627737	HCT116	viability after 9 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	-1.043845318895712	[414]	[17,81]	-6	hSpCas9	negative selection	1960432
102165216	102165239	2	-	26627737	HCT116	viability after 9 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-3.085135265151168	[403]	[24,2]	-9	hSpCas9	negative selection	1960433
102168629	102168652	2	+	26627737	HCT116	viability after 9 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.41150227660310346	[598]	[31,189]	-3	hSpCas9	negative selection	1960434
102164955	102164978	2	+	26627737	HCT116	viability after 12 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.3122050790500498	[412]	[272,263,270]	3	hSpCas9	negative selection	2042746
102165215	102165238	2	-	26627737	HCT116	viability after 12 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.08754351572530505	[133]	[68,33,120]	0	hSpCas9	negative selection	2042747
102165216	102165239	2	-	26627737	HCT116	viability after 12 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.14633444137765972	[114]	[70,38,51]	-1	hSpCas9	negative selection	2042748
102168629	102168652	2	+	26627737	HCT116	viability after 12 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.005337750424541099	[205]	[102,148,72]	0	hSpCas9	negative selection	2042749
102164955	102164978	2	+	26627737	HCT116	viability after 15 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.1502951948531308	[412]	[285,205,299]	1	hSpCas9	negative selection	2125061
102165215	102165238	2	-	26627737	HCT116	viability after 15 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	1.27490989375027	[133]	[189,89,277]	8	hSpCas9	negative selection	2125062
102165216	102165239	2	-	26627737	HCT116	viability after 15 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.19646442477657255	[114]	[69,51,103]	2	hSpCas9	negative selection	2125063
102168629	102168652	2	+	26627737	HCT116	viability after 15 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.7451961544740027	[205]	[184,185,221]	6	hSpCas9	negative selection	2125064
102164955	102164978	2	+	26627737	HCT116	viability after 18 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.15780986614515757	[412]	[168,113,261]	-1	hSpCas9	negative selection	2207376
102165215	102165238	2	-	26627737	HCT116	viability after 18 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.35123880401279417	[133]	[98,40,111]	3	hSpCas9	negative selection	2207377
102165216	102165239	2	-	26627737	HCT116	viability after 18 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.14465296080339485	[114]	[42,17,93]	-1	hSpCas9	negative selection	2207378
102168629	102168652	2	+	26627737	HCT116	viability after 18 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.9214796704279602	[205]	[236,184,141]	7	hSpCas9	negative selection	2207379
102142665	102142688	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCTCGGCTGGGCCAGTCCGCGG	IL1R1	ENSG00000115594	0.7734278570867521	[0,16]	[5,0]	3	dCas9-VP64	positive selection	2384897
102142626	102142649	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGTGGAGAGTTGGGACACCCGG	IL1R1	ENSG00000115594	4.914292410872348	[0,2]	[2,27]	9	dCas9-VP64	positive selection	2384898
102142605	102142628	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCCAGCCGCGCCTGCTCCTCCGG	IL1R1	ENSG00000115594	0.8794144710684257	[209,225]	[143,27]	3	dCas9-VP64	positive selection	2384899
102072168	102072191	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGAACTGCTTGAACCCGGGAGG	IL1R1	ENSG00000115594	-0.49490286023555685	[54,83]	[3,16]	-2	dCas9-VP64	positive selection	2421103
102070255	102070278	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTGGAGCTGCTGACCTCTTGGG	IL1R1	ENSG00000115594	-1.597917699427242	[172,212]	[18,7]	-8	dCas9-VP64	positive selection	2425388
102070201	102070224	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCAAACTGGAATGGAGTGGGG	IL1R1	ENSG00000115594	1.465657938437149	[352,178]	[255,57]	5	dCas9-VP64	positive selection	2425389
102070225	102070248	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGAAGGCAGCCCAGAAGCAAGG	IL1R1	ENSG00000115594	1.6021907880591084	[50,14]	[33,8]	6	dCas9-VP64	positive selection	2425390
102142665	102142688	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCTCGGCTGGGCCAGTCCGCGG	IL1R1	ENSG00000115594	1.0949999804328792	[25,8]	[21,1]	7	dCas9-VP64	positive selection	2480152
102142626	102142649	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGTGGAGAGTTGGGACACCCGG	IL1R1	ENSG00000115594	1.097742443928426	[8,106]	[46,32]	7	dCas9-VP64	positive selection	2480153
102142605	102142628	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCCAGCCGCGCCTGCTCCTCCGG	IL1R1	ENSG00000115594	-0.36479551739391325	[230,149]	[35,58]	-4	dCas9-VP64	positive selection	2480154
102072168	102072191	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGAACTGCTTGAACCCGGGAGG	IL1R1	ENSG00000115594	0.07163893759037979	[96,162]	[32,54]	0	dCas9-VP64	positive selection	2516358
102070255	102070278	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTGGAGCTGCTGACCTCTTGGG	IL1R1	ENSG00000115594	0.23540485914076698	[67,72]	[22,29]	1	dCas9-VP64	positive selection	2520643
102070201	102070224	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCAAACTGGAATGGAGTGGGG	IL1R1	ENSG00000115594	2.0599657226634505	[94,136]	[26,278]	8	dCas9-VP64	positive selection	2520644
102070225	102070248	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGAAGGCAGCCCAGAAGCAAGG	IL1R1	ENSG00000115594	-1.1022237715403107	[77,353]	[36,27]	-9	dCas9-VP64	positive selection	2520645
102164959	102164982	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.005226666884361238	[3,3]	[2,3]	0	hSpCas9	positive selection	2995310
102164924	102164947	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.09014454077308248	[5,5]	[4,4]	1	hSpCas9	positive selection	2995311
102164959	102164982	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	-0.9665215182047059	[3,3]	[1,0]	-9	hSpCas9	positive selection	3063168
102164924	102164947	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	-0.14317153409542133	[5,5]	[4,2]	-2	hSpCas9	positive selection	3063169
102165203	102165226		+	24336571	A375	resistance to PLX after 7 days	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-0.30697387073530247	[20,20]	[15,17]	-8	hSpCas9	positive selection	3120863
102164927	102164950		-	24336571	A375	resistance to PLX after 7 days	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.07845670617964284	[24,22]	[22,25]	2	hSpCas9	positive selection	3120865
102165170	102165193		-	24336571	A375	resistance to PLX after 7 days	TGTGCATTATAACATAAGTTAGG	IL1R1	ENSG00000115594	0.18825176923891487	[13,14]	[17,13]	6	hSpCas9	positive selection	3120866
102165203	102165226		+	24336571	A375	resistance to PLX after 14 days	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-1.1767197222378043	[30,20]	[4,3]	-9	hSpCas9	positive selection	3178656
102164927	102164950		-	24336571	A375	resistance to PLX after 14 days	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.035171412514894085	[26,29]	[12,12]	0	hSpCas9	positive selection	3178658
102165170	102165193		-	24336571	A375	resistance to PLX after 14 days	TGTGCATTATAACATAAGTTAGG	IL1R1	ENSG00000115594	0.7456026465858341	[10,12]	[7,10]	6	hSpCas9	positive selection	3178659
102165203	102165226		+	24336571	A375	viability after 7 days	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.21804798007944348	[18]	[20,20]	3	hSpCas9	negative selection	3236449
102164927	102164950		-	24336571	A375	viability after 7 days	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.32775602124837067	[19]	[24,22]	5	hSpCas9	negative selection	3236451
102165170	102165193		-	24336571	A375	viability after 7 days	TGTGCATTATAACATAAGTTAGG	IL1R1	ENSG00000115594	0.301055163367391	[11]	[13,14]	4	hSpCas9	negative selection	3236452
102165203	102165226		+	24336571	A375	viability after 14 days	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.5066301706274311	[18]	[30,20]	6	hSpCas9	negative selection	3294242
102164927	102164950		-	24336571	A375	viability after 14 days	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.5872343027296912	[19]	[26,29]	7	hSpCas9	negative selection	3294244
102165170	102165193		-	24336571	A375	viability after 14 days	TGTGCATTATAACATAAGTTAGG	IL1R1	ENSG00000115594	0.07837707032300208	[11]	[10,12]	1	hSpCas9	negative selection	3294245
102168633	102168656	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	-0.42215388805961096	[204,204]	[0,0]	-3	hSpCas9	positive selection	3374127
102168629	102168652	2	+	27383988	293T	resistance to West Nile virus (flavivirus)	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3374128
102164927	102164950	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.6574133692587072	[96,96]	[0,0]	3	hSpCas9	positive selection	3374129
102165276	102165299	2	+	26780180	HT29	viability (Avana library 4 designs)	ATGAGTTACCTAAATTACAGTGG	IL1R1	ENSG00000115594	1.3867971439306	[]	[]	5	hSpCas9	negative selection	3432675
102164848	102164871	2	+	26780180	HT29	viability (Avana library 4 designs)	CTTAACCCAAATGAACACAAAGG	IL1R1	ENSG00000115594	0.424110551192579	[]	[]	1	hSpCas9	negative selection	3432676
102164958	102164981	2	+	26780180	HT29	viability (Avana library 4 designs)	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.915998619683982	[]	[]	3	hSpCas9	negative selection	3432677
102164924	102164947	2	-	26780180	HT29	viability (Avana library 4 designs)	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	-0.00374901616846207	[]	[]	0	hSpCas9	negative selection	3432678
102164848	102164871	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTAACCCAAATGAACACAAAGG	IL1R1	ENSG00000115594	-7.45925992651498	[]	[]	-6	hSpCas9	negative selection	3518933
102165276	102165299	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAGTTACCTAAATTACAGTGG	IL1R1	ENSG00000115594	-9.43636101958345	[]	[]	-7	hSpCas9	negative selection	3518934
102164924	102164947	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	2.5455649303549	[]	[]	4	hSpCas9	negative selection	3518935
102164958	102164981	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	2.96928104175231	[]	[]	4	hSpCas9	negative selection	3518936
102164848	102164871	2	+	26780180	A375	viability (Avana lentiGuide)	CTTAACCCAAATGAACACAAAGG	IL1R1	ENSG00000115594	-3.72147647525217	[]	[]	-6	hSpCas9	negative selection	3627592
102165276	102165299	2	+	26780180	A375	viability (Avana lentiGuide)	ATGAGTTACCTAAATTACAGTGG	IL1R1	ENSG00000115594	-0.714135168440839	[]	[]	-1	hSpCas9	negative selection	3627593
102164924	102164947	2	-	26780180	A375	viability (Avana lentiGuide)	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.221514378313139	[]	[]	0	hSpCas9	negative selection	3627594
102164958	102164981	2	+	26780180	A375	viability (Avana lentiGuide)	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	2.76101305828914	[]	[]	3	hSpCas9	negative selection	3627595
102164848	102164871	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTAACCCAAATGAACACAAAGG	IL1R1	ENSG00000115594	-0.7681453433891315	[5]	[2,2]	-8	hSpCas9	positive selection	3736251
102165276	102165299	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAGTTACCTAAATTACAGTGG	IL1R1	ENSG00000115594	-0.918018946277787	[7]	[4,2]	-8	hSpCas9	positive selection	3736252
102164924	102164947	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.12217791697345523	[6]	[7,5]	3	hSpCas9	positive selection	3736253
102164958	102164981	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.14156372991194593	[4]	[5,4]	4	hSpCas9	positive selection	3736254
102164848	102164871	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTAACCCAAATGAACACAAAGG	IL1R1	ENSG00000115594	0.45212216370546815	[4]	[6,4]	9	hSpCas9	positive selection	3844858
102165276	102165299	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAGTTACCTAAATTACAGTGG	IL1R1	ENSG00000115594	-0.011619521005962766	[4]	[3,4]	0	hSpCas9	positive selection	3844859
102164924	102164947	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.21134270013751205	[7]	[7,6]	5	hSpCas9	positive selection	3844860
102164958	102164981	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	-0.053081262335608365	[4]	[2,5]	0	hSpCas9	positive selection	3844861
102165203	102165226	2	+	26780180	A375	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	1.84072719480638	[]	[]	9	hSpCas9	negative selection	3950821
102165216	102165239	2	-	26780180	A375	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	1.18403836048442	[]	[]	6	hSpCas9	negative selection	3950822
102168633	102168656	2	-	26780180	A375	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.765200902759167	[]	[]	3	hSpCas9	negative selection	3950823
102164927	102164950	2	-	26780180	A375	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.992694176135587	[]	[]	4	hSpCas9	negative selection	3950824
102168629	102168652	2	+	26780180	A375	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.03394563408533	[]	[]	5	hSpCas9	negative selection	3950825
102166237	102166260	2	+	26780180	A375	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	1.078605559564	[]	[]	5	hSpCas9	negative selection	3950826
102165203	102165226	2	+	26780180	HT29	viability (GeCKOv2 library)	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	2.07800016381917	[]	[]	9	hSpCas9	negative selection	4058787
102165216	102165239	2	-	26780180	HT29	viability (GeCKOv2 library)	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.82229040424006	[]	[]	3	hSpCas9	negative selection	4058788
102168633	102168656	2	-	26780180	HT29	viability (GeCKOv2 library)	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	1.11150379166392	[]	[]	5	hSpCas9	negative selection	4058789
102164927	102164950	2	-	26780180	HT29	viability (GeCKOv2 library)	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	1.01162922968981	[]	[]	4	hSpCas9	negative selection	4058790
102168629	102168652	2	+	26780180	HT29	viability (GeCKOv2 library)	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.82290264723546	[]	[]	3	hSpCas9	negative selection	4058791
102166237	102166260	2	+	26780180	HT29	viability (GeCKOv2 library)	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	1.4403646214028	[]	[]	7	hSpCas9	negative selection	4058792
102165203	102165226	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.03170870240614568	[3]	[2,2]	0	hSpCas9	positive selection	4144501
102164927	102164950	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.16834355632334067	[4]	[2,3]	4	hSpCas9	positive selection	4144503
102165170	102165193	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGCATTATAACATAAGTTAGG	IL1R1	ENSG00000115594	0.2961015475875921	[3]	[1,3]	7	hSpCas9	positive selection	4144504
102165203	102165226	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.889719406450366	[3]	[1,1,0,4]	6	hSpCas9	positive selection	4208523
102164927	102164950	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.936597108640473	[4]	[3,0,2,4]	6	hSpCas9	positive selection	4208525
102165170	102165193	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGCATTATAACATAAGTTAGG	IL1R1	ENSG00000115594	1.148084593565666	[3]	[2,3,3,3]	8	hSpCas9	positive selection	4208526
102165203	102165226	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-0.5198869046553534	[3]	[2,0]	-8	hSpCas9	positive selection	4276725
102165216	102165239	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.9591627972247689	[2]	[2,4]	9	hSpCas9	positive selection	4276726
102166237	102166260	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.059660201329944096	[2]	[1,1]	-1	hSpCas9	positive selection	4276727
102168633	102168656	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	-0.2578695806663547	[2]	[2,0]	-5	hSpCas9	positive selection	4340983
102168629	102168652	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.3749528598624796	[3]	[3,2]	7	hSpCas9	positive selection	4340984
102164927	102164950	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	-0.13052652465945097	[2]	[2,0]	-3	hSpCas9	positive selection	4340985
102164956	102164978	2	+	27760321	OCIAML3	viability	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	1.0077046055046353	[394,358]	[644,523]	9	hSpCas9	negative selection	4409419
102166164	102166186	2	+	27760321	OCIAML3	viability	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.09239878074241384	[451,304]	[308,314]	1	hSpCas9	negative selection	4409420
102166239	102166261	2	+	27760321	OCIAML3	viability	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	1.1733915440888403	[99,96]	[154,198]	9	hSpCas9	negative selection	4409421
102168630	102168652	2	+	27760321	OCIAML3	viability	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.8224902460351172	[339,210]	[354,400]	8	hSpCas9	negative selection	4409422
102171835	102171857	2	-	27760321	OCIAML3	viability	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.3032485629882538	[314,255]	[244,311]	3	hSpCas9	negative selection	4409423
102164956	102164978	2	+	27760321	OCIAML2	viability	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.8590424620618323	[394,358]	[535,574]	9	hSpCas9	negative selection	4492882
102166164	102166186	2	+	27760321	OCIAML2	viability	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.05235466076935119	[451,304]	[262,379]	0	hSpCas9	negative selection	4492883
102166239	102166261	2	+	27760321	OCIAML2	viability	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	0.3358787501446525	[99,96]	[70,139]	4	hSpCas9	negative selection	4492884
102168630	102168652	2	+	27760321	OCIAML2	viability	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.6355530471157301	[339,210]	[360,313]	8	hSpCas9	negative selection	4492885
102171835	102171857	2	-	27760321	OCIAML2	viability	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.228934259679548	[314,255]	[229,320]	3	hSpCas9	negative selection	4492886
102164956	102164978	2	+	27760321	MV411	viability	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.38428246983562897	[394,358]	[212,491]	2	hSpCas9	negative selection	4576345
102166164	102166186	2	+	27760321	MV411	viability	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.13041012151850653	[451,304]	[199,374]	0	hSpCas9	negative selection	4576346
102166239	102166261	2	+	27760321	MV411	viability	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	2.3599317622986877	[99,96]	[520,53]	9	hSpCas9	negative selection	4576347
102168630	102168652	2	+	27760321	MV411	viability	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.0759223662319508	[339,210]	[311,474]	7	hSpCas9	negative selection	4576348
102171835	102171857	2	-	27760321	MV411	viability	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.19864369428657885	[314,255]	[81,414]	1	hSpCas9	negative selection	4576349
102164956	102164978	2	+	27760321	HL60	viability	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.35222909827247284	[394,358]	[338,449]	4	hSpCas9	negative selection	4659808
102166164	102166186	2	+	27760321	HL60	viability	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	1.262088929535184	[451,304]	[704,760]	9	hSpCas9	negative selection	4659809
102166239	102166261	2	+	27760321	HL60	viability	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	0.22571015962150254	[99,96]	[86,101]	2	hSpCas9	negative selection	4659810
102168630	102168652	2	+	27760321	HL60	viability	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.7198331614751436	[339,210]	[372,355]	8	hSpCas9	negative selection	4659811
102171835	102171857	2	-	27760321	HL60	viability	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.19914463315915987	[314,255]	[310,218]	2	hSpCas9	negative selection	4659812
102164956	102164978	2	+	27760321	HT1080	viability	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.431309287674848	[358,279]	[110,237]	2	hSpCas9	negative selection	4743271
102166164	102166186	2	+	27760321	HT1080	viability	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	1.5220158917263487	[304,237]	[291,330]	8	hSpCas9	negative selection	4743272
102166239	102166261	2	+	27760321	HT1080	viability	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-1.2625867223635785	[96,75]	[0,28]	-5	hSpCas9	negative selection	4743273
102168630	102168652	2	+	27760321	HT1080	viability	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.9382583059503522	[210,164]	[101,188]	5	hSpCas9	negative selection	4743274
102171835	102171857	2	-	27760321	HT1080	viability	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.05997567656814706	[255,199]	[45,147]	0	hSpCas9	negative selection	4743275
102164956	102164978	2	+	27760321	HT29	viability after 7 days	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.42946572825306223	[358,279]	[383,177,361]	-6	hSpCas9	negative selection	4826734
102166164	102166186	2	+	27760321	HT29	viability after 7 days	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	-0.31577647015960275	[304,237]	[413,356,94]	-4	hSpCas9	negative selection	4826735
102166239	102166261	2	+	27760321	HT29	viability after 7 days	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	0.8318523209734516	[96,75]	[109,330,141]	9	hSpCas9	negative selection	4826736
102168630	102168652	2	+	27760321	HT29	viability after 7 days	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.619756538712951	[210,164]	[265,466,365]	8	hSpCas9	negative selection	4826737
102171835	102171857	2	-	27760321	HT29	viability after 7 days	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.24386490286042295	[255,199]	[344,359,335]	4	hSpCas9	negative selection	4826738
102164956	102164978	2	+	27760321	HT29	viability after 25 days	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.1740359777041655	[358,279]	[258,412,299]	-2	hSpCas9	negative selection	4910197
102166164	102166186	2	+	27760321	HT29	viability after 25 days	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.2517290584757119	[304,237]	[352,340,419]	2	hSpCas9	negative selection	4910198
102166239	102166261	2	+	27760321	HT29	viability after 25 days	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-0.9977864660003268	[96,75]	[71,25,48]	-6	hSpCas9	negative selection	4910199
102168630	102168652	2	+	27760321	HT29	viability after 25 days	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.417563902487746	[210,164]	[630,482,606]	9	hSpCas9	negative selection	4910200
102171835	102171857	2	-	27760321	HT29	viability after 25 days	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.7149743955944137	[255,199]	[329,536,420]	7	hSpCas9	negative selection	4910201
102164956	102164978	2	+	27760321	HT29	viability after 22 days	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.18674432560659598	[358,279]	[262,402,308]	-2	hSpCas9	negative selection	4993660
102166164	102166186	2	+	27760321	HT29	viability after 22 days	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.4533771941892061	[304,237]	[443,400,443]	5	hSpCas9	negative selection	4993661
102166239	102166261	2	+	27760321	HT29	viability after 22 days	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-0.3039851259644597	[96,75]	[41,27,174]	-3	hSpCas9	negative selection	4993662
102168630	102168652	2	+	27760321	HT29	viability after 22 days	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.1656142576274733	[210,164]	[585,401,471]	9	hSpCas9	negative selection	4993663
102171835	102171857	2	-	27760321	HT29	viability after 22 days	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.8284183878349543	[255,199]	[622,415,359]	8	hSpCas9	negative selection	4993664
102164956	102164978	2	+	27760321	HT29	viability after 19 days	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.24022791266033638	[358,279]	[416,263,259]	-2	hSpCas9	negative selection	5077123
102166164	102166186	2	+	27760321	HT29	viability after 19 days	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	-0.06521400867519367	[304,237]	[224,343,312]	0	hSpCas9	negative selection	5077124
102166239	102166261	2	+	27760321	HT29	viability after 19 days	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-0.216706394074083	[96,75]	[57,40,150]	-2	hSpCas9	negative selection	5077125
102168630	102168652	2	+	27760321	HT29	viability after 19 days	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.7179015336488189	[210,164]	[419,192,450]	7	hSpCas9	negative selection	5077126
102171835	102171857	2	-	27760321	HT29	viability after 19 days	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.7889139281209101	[255,199]	[288,528,513]	7	hSpCas9	negative selection	5077127
102164956	102164978	2	+	27760321	HT29	viability after 16 days	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.48690047913423945	[358,279]	[313,319,134]	-5	hSpCas9	negative selection	5160586
102166164	102166186	2	+	27760321	HT29	viability after 16 days	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.7484281505357806	[304,237]	[517,491,521]	8	hSpCas9	negative selection	5160587
102166239	102166261	2	+	27760321	HT29	viability after 16 days	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-1.3191795837015792	[96,75]	[21,68,22]	-7	hSpCas9	negative selection	5160588
102168630	102168652	2	+	27760321	HT29	viability after 16 days	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.9449617363254846	[210,164]	[386,410,414]	9	hSpCas9	negative selection	5160589
102171835	102171857	2	-	27760321	HT29	viability after 16 days	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.5944014160579295	[255,199]	[298,319,529]	7	hSpCas9	negative selection	5160590
102164956	102164978	2	+	27760321	HT29	viability after 13 days	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.4121210741481524	[358,279]	[240,355,240]	-5	hSpCas9	negative selection	5244049
102166164	102166186	2	+	27760321	HT29	viability after 13 days	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	-0.11895953314187102	[304,237]	[316,211,337]	-1	hSpCas9	negative selection	5244050
102166239	102166261	2	+	27760321	HT29	viability after 13 days	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-0.4400539958890728	[96,75]	[20,159,42]	-5	hSpCas9	negative selection	5244051
102168630	102168652	2	+	27760321	HT29	viability after 13 days	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.5637044873327708	[210,164]	[260,429,278]	7	hSpCas9	negative selection	5244052
102171835	102171857	2	-	27760321	HT29	viability after 13 days	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	-0.043976150339087194	[255,199]	[199,196,365]	0	hSpCas9	negative selection	5244053
102164956	102164978	2	+	27760321	HT29	viability after 10 days	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.15693395936787397	[358,279]	[516,549,273]	2	hSpCas9	negative selection	5327512
102166164	102166186	2	+	27760321	HT29	viability after 10 days	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.07087231108138503	[304,237]	[260,436,371]	0	hSpCas9	negative selection	5327513
102166239	102166261	2	+	27760321	HT29	viability after 10 days	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-1.1299808530064102	[96,75]	[26,77,43]	-8	hSpCas9	negative selection	5327514
102168630	102168652	2	+	27760321	HT29	viability after 10 days	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.7688973643501822	[210,164]	[256,804,154]	9	hSpCas9	negative selection	5327515
102171835	102171857	2	-	27760321	HT29	viability after 10 days	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.424309278981082	[255,199]	[151,343,642]	6	hSpCas9	negative selection	5327516
102164956	102164978	2	+	27760321	MOLM13	viability	TGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.15772012864145962	[394,358]	[295,186]	1	hSpCas9	negative selection	5410975
102166164	102166186	2	+	27760321	MOLM13	viability	AGGCTCATCGTGATGAATGTGG	IL1R1	ENSG00000115594	0.19495293208539372	[451,304]	[202,273]	1	hSpCas9	negative selection	5410976
102166239	102166261	2	+	27760321	MOLM13	viability	AAGCAATATCCTATTACCCGGG	IL1R1	ENSG00000115594	-1.390470513338042	[99,96]	[17,23]	-7	hSpCas9	negative selection	5410977
102168630	102168652	2	+	27760321	MOLM13	viability	AGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	2.7152129254265	[339,210]	[1858,276]	9	hSpCas9	negative selection	5410978
102171835	102171857	2	-	27760321	MOLM13	viability	GTAAGCAATGTCACTCAACTGG	IL1R1	ENSG00000115594	0.06047825888220337	[314,255]	[232,110]	0	hSpCas9	negative selection	5410979
102142779	102142802	2	+	27661255	K562	viability	GCCGGCGGCCGGAGCCGACTCGG	IL1R1	ENSG00000115594	0.15562105983807928	[1120,1085]	[1023,946]	5	dCas9-KRAB	negative selection	5486635
102142820	102142843	2	+	27661255	K562	viability	GGAGGAGCCGGAGAGCGGCCGGG	IL1R1	ENSG00000115594	-0.08589326825753346	[806,929]	[685,622]	-3	dCas9-KRAB	negative selection	5486636
102142975	102142998	2	-	27661255	K562	viability	GATGGGATCCCAGCCCCGGGCGG	IL1R1	ENSG00000115594	-0.2793231385778723	[1572,1614]	[1147,963]	-6	dCas9-KRAB	negative selection	5486637
102142978	102143001	2	-	27661255	K562	viability	GGTGATGGGATCCCAGCCCCGGG	IL1R1	ENSG00000115594	-0.03009761887340523	[1172,1193]	[1113,764]	-1	dCas9-KRAB	negative selection	5486638
102142992	102143015	2	-	27661255	K562	viability	GGACGGCCGTGGAGGGTGATGGG	IL1R1	ENSG00000115594	-0.02878825396593479	[585,732]	[509,517]	-1	dCas9-KRAB	negative selection	5486639
102165203	102165226	2	+	27260156	BXPC3	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.28586216167354317	[485]	[490,580,597,847]	6	hSpCas9	negative selection	5549185
102165216	102165239	2	-	27260156	BXPC3	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.04990152154979177	[240]	[179,290,297,202]	-1	hSpCas9	negative selection	5549186
102166237	102166260	2	+	27260156	BXPC3	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.06476716972167385	[216]	[235,136,333,249]	1	hSpCas9	negative selection	5549187
102168633	102168656	2	-	27260156	BXPC3	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.10325021923894945	[341]	[355,404,329,451]	2	hSpCas9	negative selection	5613443
102168629	102168652	2	+	27260156	BXPC3	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.27158933762602655	[511]	[681,648,657,578]	6	hSpCas9	negative selection	5613444
102164927	102164950	2	-	27260156	BXPC3	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.1883667379305487	[220]	[251,222,209,383]	4	hSpCas9	negative selection	5613445
102165203	102165226	2	+	27260156	A673	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.021000419188932237	[485]	[591,466,533,788]	0	hSpCas9	negative selection	5670436
102165216	102165239	2	-	27260156	A673	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.05791757233707395	[240]	[408,207,332,266]	1	hSpCas9	negative selection	5670437
102166237	102166260	2	+	27260156	A673	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.32603154241493937	[216]	[218,214,164,234]	-7	hSpCas9	negative selection	5670438
102168633	102168656	2	-	27260156	A673	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.30716848018609805	[341]	[499,455,584,488]	7	hSpCas9	negative selection	5734694
102168629	102168652	2	+	27260156	A673	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.12292158229469856	[511]	[758,614,738,568]	3	hSpCas9	negative selection	5734695
102164927	102164950	2	-	27260156	A673	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.0428202132364508	[220]	[319,201,272,306]	1	hSpCas9	negative selection	5734696
102165203	102165226	2	+	27260156	A375	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.11938106417573768	[485]	[655,737,634,469]	1	hSpCas9	negative selection	5791687
102165216	102165239	2	-	27260156	A375	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.050371137571555646	[240]	[377,215,247,240]	0	hSpCas9	negative selection	5791688
102166237	102166260	2	+	27260156	A375	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.13588843313701582	[216]	[222,254,313,312]	2	hSpCas9	negative selection	5791689
102168633	102168656	2	-	27260156	A375	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.4573172003494929	[341]	[456,713,503,539]	6	hSpCas9	negative selection	5855945
102168629	102168652	2	+	27260156	A375	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.05743011002102018	[511]	[273,851,753,465]	-1	hSpCas9	negative selection	5855946
102164927	102164950	2	-	27260156	A375	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.6569631548451162	[220]	[225,449,454,489]	8	hSpCas9	negative selection	5855947
102165203	102165226	2	+	27260156	COLO741	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-0.2251179088738652	[485]	[628,514,461]	-5	hSpCas9	negative selection	5912938
102165216	102165239	2	-	27260156	COLO741	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.03260293498544564	[240]	[346,314,286]	0	hSpCas9	negative selection	5912939
102166237	102166260	2	+	27260156	COLO741	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.24060194759308406	[216]	[271,163,267]	-5	hSpCas9	negative selection	5912940
102168633	102168656	2	-	27260156	COLO741	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.32188497842499586	[341]	[456,570,597]	6	hSpCas9	negative selection	5977196
102168629	102168652	2	+	27260156	COLO741	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.2799876683811778	[511]	[718,482,435]	-5	hSpCas9	negative selection	5977197
102164927	102164950	2	-	27260156	COLO741	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.13026141842331762	[220]	[251,391,279]	2	hSpCas9	negative selection	5977198
102165203	102165226	2	+	27260156	CAL120	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-0.0024593590827902204	[485]	[841,410,593]	0	hSpCas9	negative selection	6034189
102165216	102165239	2	-	27260156	CAL120	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.029113569290590502	[240]	[368,179,342]	0	hSpCas9	negative selection	6034190
102166237	102166260	2	+	27260156	CAL120	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.006739015633209666	[216]	[246,234,319]	0	hSpCas9	negative selection	6034191
102168633	102168656	2	-	27260156	CAL120	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.3254396419766431	[341]	[543,679,379]	5	hSpCas9	negative selection	6098447
102168629	102168652	2	+	27260156	CAL120	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.18035223016261642	[511]	[530,597,552]	-3	hSpCas9	negative selection	6098448
102164927	102164950	2	-	27260156	CAL120	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.267128304312261	[220]	[369,208,417]	4	hSpCas9	negative selection	6098449
102165203	102165226	2	+	27260156	CADOES1	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.08227631621958334	[485]	[305,544,449,618]	1	hSpCas9	negative selection	6155440
102165216	102165239	2	-	27260156	CADOES1	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.15900431129579096	[240]	[209,277,267,244]	2	hSpCas9	negative selection	6155441
102166237	102166260	2	+	27260156	CADOES1	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.14132572316737457	[216]	[102,365,147,275]	2	hSpCas9	negative selection	6155442
102168633	102168656	2	-	27260156	CADOES1	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.3111176490378267	[341]	[438,466,292,378]	5	hSpCas9	negative selection	6219698
102168629	102168652	2	+	27260156	CADOES1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.4298798873375619	[511]	[297,343,368,404]	-6	hSpCas9	negative selection	6219699
102164927	102164950	2	-	27260156	CADOES1	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.37222828440782385	[220]	[254,192,248,370]	6	hSpCas9	negative selection	6219700
102165203	102165226	2	+	27260156	EWS502	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.29074261930821677	[485]	[581,607,768,560]	5	hSpCas9	negative selection	6276691
102165216	102165239	2	-	27260156	EWS502	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.3225903346347927	[240]	[204,222,125,263]	-5	hSpCas9	negative selection	6276692
102166237	102166260	2	+	27260156	EWS502	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.07036758452355563	[216]	[225,192,246,306]	1	hSpCas9	negative selection	6276693
102168633	102168656	2	-	27260156	EWS502	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.3039100180102804	[341]	[249,464,650,446]	5	hSpCas9	negative selection	6340949
102168629	102168652	2	+	27260156	EWS502	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.028004072223503554	[511]	[495,410,569,667]	0	hSpCas9	negative selection	6340950
102164927	102164950	2	-	27260156	EWS502	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.7423267217331212	[220]	[417,305,480,358]	9	hSpCas9	negative selection	6340951
102165203	102165226	2	+	27260156	EW8	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.2533092739211483	[485]	[799,573,262,311]	4	hSpCas9	negative selection	6397942
102165216	102165239	2	-	27260156	EW8	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.20271338107078374	[240]	[291,203,181,234]	4	hSpCas9	negative selection	6397943
102166237	102166260	2	+	27260156	EW8	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.30241934889340727	[216]	[161,126,154,125]	-5	hSpCas9	negative selection	6397944
102168633	102168656	2	-	27260156	EW8	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.638963981200459	[341]	[390,454,327,563]	9	hSpCas9	negative selection	6462200
102168629	102168652	2	+	27260156	EW8	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.06323812651963208	[511]	[585,372,430,359]	1	hSpCas9	negative selection	6462201
102164927	102164950	2	-	27260156	EW8	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	-0.04945538674520722	[220]	[244,143,158,153]	-1	hSpCas9	negative selection	6462202
102165203	102165226	2	+	27260156	CORL105	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.10592704992243918	[485]	[674,426,716,651]	2	hSpCas9	negative selection	6519193
102165216	102165239	2	-	27260156	CORL105	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.21040011036328976	[240]	[168,290,226,281]	-4	hSpCas9	negative selection	6519194
102166237	102166260	2	+	27260156	CORL105	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.4054790077337319	[216]	[368,308,395,282]	7	hSpCas9	negative selection	6519195
102168633	102168656	2	-	27260156	CORL105	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.22382613790700162	[341]	[465,551,587,281]	4	hSpCas9	negative selection	6583451
102168629	102168652	2	+	27260156	CORL105	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.0947533739096952	[511]	[772,586,639,565]	1	hSpCas9	negative selection	6583452
102164927	102164950	2	-	27260156	CORL105	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.4133130654215236	[220]	[372,377,352,275]	7	hSpCas9	negative selection	6583453
102165203	102165226	2	+	27260156	HS294T	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-0.2103670855738039	[485]	[128,209,137,175]	-3	hSpCas9	negative selection	6640444
102165216	102165239	2	-	27260156	HS294T	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.30115982929935603	[240]	[56,93,73,78]	-4	hSpCas9	negative selection	6640445
102166237	102166260	2	+	27260156	HS294T	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.2550657348907641	[216]	[158,58,76,100]	3	hSpCas9	negative selection	6640446
102168633	102168656	2	-	27260156	HS294T	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.4773697953511598	[341]	[208,207,133,180]	6	hSpCas9	negative selection	6704702
102168629	102168652	2	+	27260156	HS294T	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.15534279152747016	[511]	[262,159,155,315]	2	hSpCas9	negative selection	6704703
102164927	102164950	2	-	27260156	HS294T	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	-0.10956307415423727	[220]	[72,62,80,104]	-1	hSpCas9	negative selection	6704704
102165203	102165226	2	+	27260156	HCC44	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.1935399082933044	[485]	[720,376,813,671]	3	hSpCas9	negative selection	6761695
102165216	102165239	2	-	27260156	HCC44	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.6843283946299734	[240]	[270,84,152,185]	-7	hSpCas9	negative selection	6761696
102166237	102166260	2	+	27260156	HCC44	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.9626728636255264	[216]	[68,144,166,120]	-8	hSpCas9	negative selection	6761697
102168633	102168656	2	-	27260156	HCC44	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.11214649265915311	[341]	[656,353,339,337]	1	hSpCas9	negative selection	6825953
102168629	102168652	2	+	27260156	HCC44	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.9221881165211157	[511]	[260,382,273,281]	-8	hSpCas9	negative selection	6825954
102164927	102164950	2	-	27260156	HCC44	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	-0.04677497885650861	[220]	[332,163,260,230]	-1	hSpCas9	negative selection	6825955
102165203	102165226	2	+	27260156	G402	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.40205949428972176	[485]	[701,1012,783,640]	5	hSpCas9	negative selection	6882946
102165216	102165239	2	-	27260156	G402	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.8050689099488961	[240]	[147,104,181,227]	-7	hSpCas9	negative selection	6882947
102166237	102166260	2	+	27260156	G402	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.0027226562237909757	[216]	[433,188,204,248]	0	hSpCas9	negative selection	6882948
102168633	102168656	2	-	27260156	G402	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.5410404265952993	[341]	[468,906,527,523]	6	hSpCas9	negative selection	6947204
102168629	102168652	2	+	27260156	G402	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.12419575090393516	[511]	[669,733,499,811]	1	hSpCas9	negative selection	6947205
102164927	102164950	2	-	27260156	G402	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.07144439802448099	[220]	[549,259,150,211]	0	hSpCas9	negative selection	6947206
102165203	102165226	2	+	27260156	L33	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.042595076732546144	[485]	[459,221,332,471]	1	hSpCas9	negative selection	7004197
102165216	102165239	2	-	27260156	L33	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.20674283623905432	[240]	[264,99,209,269]	4	hSpCas9	negative selection	7004198
102166237	102166260	2	+	27260156	L33	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.14617902821197903	[216]	[260,60,105,203]	-3	hSpCas9	negative selection	7004199
102168633	102168656	2	-	27260156	L33	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.44092560695425626	[341]	[450,167,314,494]	8	hSpCas9	negative selection	7068455
102168629	102168652	2	+	27260156	L33	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.319940736419253	[511]	[453,178,255,341]	-6	hSpCas9	negative selection	7068456
102164927	102164950	2	-	27260156	L33	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	-0.14558953149352694	[220]	[130,84,159,207]	-3	hSpCas9	negative selection	7068457
102165203	102165226	2	+	27260156	K562	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.3410864866982577	[485]	[592,704,613,310]	4	hSpCas9	negative selection	7125448
102165216	102165239	2	-	27260156	K562	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.3103702963698234	[240]	[305,176,88,132]	-4	hSpCas9	negative selection	7125449
102166237	102166260	2	+	27260156	K562	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.21277421182264988	[216]	[135,265,53,205]	-3	hSpCas9	negative selection	7125450
102168633	102168656	2	-	27260156	K562	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.14377023143414752	[341]	[313,327,174,500]	1	hSpCas9	negative selection	7189706
102168629	102168652	2	+	27260156	K562	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.11432791083443969	[511]	[456,324,338,539]	-1	hSpCas9	negative selection	7189707
102164927	102164950	2	-	27260156	K562	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.8904341133861721	[220]	[241,484,234,473]	9	hSpCas9	negative selection	7189708
102165203	102165226	2	+	27260156	HT29	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.25471513528291656	[485]	[748,704,759,614]	5	hSpCas9	negative selection	7246699
102165216	102165239	2	-	27260156	HT29	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.15083434442936583	[240]	[315,357,294,330]	3	hSpCas9	negative selection	7246700
102166237	102166260	2	+	27260156	HT29	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.3323774531833221	[216]	[150,164,300,210]	-6	hSpCas9	negative selection	7246701
102168633	102168656	2	-	27260156	HT29	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.4070598314032124	[341]	[606,537,631,440]	7	hSpCas9	negative selection	7310957
102168629	102168652	2	+	27260156	HT29	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.12087186991791025	[511]	[729,741,626,619]	2	hSpCas9	negative selection	7310958
102164927	102164950	2	-	27260156	HT29	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.3134832767210918	[220]	[298,299,399,328]	6	hSpCas9	negative selection	7310959
102165203	102165226	2	+	27260156	MHHES1	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.14209520562209307	[485]	[470,712,679,546]	2	hSpCas9	negative selection	7367950
102165216	102165239	2	-	27260156	MHHES1	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.014923359707316508	[240]	[266,257,333,219]	0	hSpCas9	negative selection	7367951
102166237	102166260	2	+	27260156	MHHES1	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.04828538712820718	[216]	[189,282,249,219]	-1	hSpCas9	negative selection	7367952
102168633	102168656	2	-	27260156	MHHES1	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.5519257318647882	[341]	[359,546,539,731]	8	hSpCas9	negative selection	7432208
102168629	102168652	2	+	27260156	MHHES1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.028872870263424263	[511]	[487,723,436,596]	0	hSpCas9	negative selection	7432209
102164927	102164950	2	-	27260156	MHHES1	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.21903349105122816	[220]	[367,143,364,273]	4	hSpCas9	negative selection	7432210
102165203	102165226	2	+	27260156	MEWO	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.19620125332065128	[485]	[609,500,468]	4	hSpCas9	negative selection	7489201
102165216	102165239	2	-	27260156	MEWO	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.11978009069948081	[240]	[306,229,209]	2	hSpCas9	negative selection	7489202
102166237	102166260	2	+	27260156	MEWO	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.37580745480624045	[216]	[225,118,137]	-7	hSpCas9	negative selection	7489203
102168633	102168656	2	-	27260156	MEWO	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.21877930372864765	[341]	[300,404,396]	5	hSpCas9	negative selection	7553459
102168629	102168652	2	+	27260156	MEWO	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.0382585407075159	[511]	[641,412,449]	0	hSpCas9	negative selection	7553460
102164927	102164950	2	-	27260156	MEWO	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.13009821475887373	[220]	[333,150,214]	3	hSpCas9	negative selection	7553461
102165203	102165226	2	+	27260156	LNCAPCLONEFGC	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.18328535777318392	[485]	[432,452,724,425]	3	hSpCas9	negative selection	7610452
102165216	102165239	2	-	27260156	LNCAPCLONEFGC	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.02291552997898283	[240]	[160,188,193,314]	0	hSpCas9	negative selection	7610453
102166237	102166260	2	+	27260156	LNCAPCLONEFGC	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.18938755169271326	[216]	[121,192,198,178]	-3	hSpCas9	negative selection	7610454
102168633	102168656	2	-	27260156	LNCAPCLONEFGC	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.29030313766997545	[341]	[421,376,422,298]	4	hSpCas9	negative selection	7674710
102168629	102168652	2	+	27260156	LNCAPCLONEFGC	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.016020066740491792	[511]	[417,467,558,444]	0	hSpCas9	negative selection	7674711
102164927	102164950	2	-	27260156	LNCAPCLONEFGC	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.4640898214413067	[220]	[173,244,346,352]	7	hSpCas9	negative selection	7674712
102165203	102165226	2	+	27260156	PANC0327	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.5876908417165018	[485]	[937,578,283,825]	8	hSpCas9	negative selection	7731703
102165216	102165239	2	-	27260156	PANC0327	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.30582492967279196	[240]	[142,104,190,259]	-4	hSpCas9	negative selection	7731704
102166237	102166260	2	+	27260156	PANC0327	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.7787529048164896	[216]	[367,281,294,386]	9	hSpCas9	negative selection	7731705
102168633	102168656	2	-	27260156	PANC0327	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	-0.018790363620088568	[341]	[501,220,210,291]	0	hSpCas9	negative selection	7795961
102168629	102168652	2	+	27260156	PANC0327	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.1665342482966116	[511]	[530,275,500,339]	-2	hSpCas9	negative selection	7795962
102164927	102164950	2	-	27260156	PANC0327	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.17306577082882224	[220]	[252,179,135,323]	2	hSpCas9	negative selection	7795963
102165203	102165226	2	+	27260156	NCIH2009	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.37734372702024904	[485]	[1066,721,894]	5	hSpCas9	negative selection	7852954
102165216	102165239	2	-	27260156	NCIH2009	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.08515598595667084	[240]	[386,403,284]	1	hSpCas9	negative selection	7852955
102166237	102166260	2	+	27260156	NCIH2009	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.0347021519370605	[216]	[216,285,368]	0	hSpCas9	negative selection	7852956
102168633	102168656	2	-	27260156	NCIH2009	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.2988904564509316	[341]	[838,428,546]	4	hSpCas9	negative selection	7917212
102168629	102168652	2	+	27260156	NCIH2009	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.43902319230527453	[511]	[484,618,467]	-5	hSpCas9	negative selection	7917213
102164927	102164950	2	-	27260156	NCIH2009	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.6801793980016099	[220]	[619,504,382]	8	hSpCas9	negative selection	7917214
102165203	102165226	2	+	27260156	NCIH1373	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.5068898037232483	[485]	[901,538,654,278]	5	hSpCas9	negative selection	7974205
102165216	102165239	2	-	27260156	NCIH1373	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.7657163492213277	[240]	[187,146,208,23]	-6	hSpCas9	negative selection	7974206
102166237	102166260	2	+	27260156	NCIH1373	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.24056493830953252	[216]	[286,187,223,34]	-2	hSpCas9	negative selection	7974207
102168633	102168656	2	-	27260156	NCIH1373	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.8555285299055895	[341]	[502,901,614,183]	8	hSpCas9	negative selection	8038463
102168629	102168652	2	+	27260156	NCIH1373	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.4111720937909663	[511]	[279,645,504,60]	-4	hSpCas9	negative selection	8038464
102164927	102164950	2	-	27260156	NCIH1373	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.5199069264966228	[220]	[504,370,237,85]	5	hSpCas9	negative selection	8038465
102165203	102165226	2	+	27260156	PATU8902	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.020569859849418573	[485]	[716,686,531,865]	0	hSpCas9	negative selection	8095456
102165216	102165239	2	-	27260156	PATU8902	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.8994416984599696	[240]	[185,148,270,75]	-7	hSpCas9	negative selection	8095457
102166237	102166260	2	+	27260156	PATU8902	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.5816499943453564	[216]	[162,132,159,382]	-5	hSpCas9	negative selection	8095458
102168633	102168656	2	-	27260156	PATU8902	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.03847572017798978	[341]	[478,547,400,555]	0	hSpCas9	negative selection	8159714
102168629	102168652	2	+	27260156	PATU8902	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.6617092935394862	[511]	[435,416,240,801]	-6	hSpCas9	negative selection	8159715
102164927	102164950	2	-	27260156	PATU8902	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.39068902077478473	[220]	[539,370,238,514]	4	hSpCas9	negative selection	8159716
102165203	102165226	2	+	27260156	PANC1	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-0.047097441536276534	[485]	[390,506,353,381]	-1	hSpCas9	negative selection	8216707
102165216	102165239	2	-	27260156	PANC1	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.2915669459108573	[240]	[223,319,243,237]	5	hSpCas9	negative selection	8216708
102166237	102166260	2	+	27260156	PANC1	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.04829266325783599	[216]	[186,135,159,218]	-1	hSpCas9	negative selection	8216709
102168633	102168656	2	-	27260156	PANC1	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.3332599024484617	[341]	[274,479,394,351]	5	hSpCas9	negative selection	8280965
102168629	102168652	2	+	27260156	PANC1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.10344230352626109	[511]	[396,468,435,350]	-2	hSpCas9	negative selection	8280966
102164927	102164950	2	-	27260156	PANC1	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.22621847529226413	[220]	[161,371,238,154]	3	hSpCas9	negative selection	8280967
102165203	102165226	2	+	27260156	PANC0813	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.26778176050513475	[485]	[860,582,684,637]	4	hSpCas9	negative selection	8337958
102165216	102165239	2	-	27260156	PANC0813	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.009853585073329785	[240]	[265,377,234,259]	0	hSpCas9	negative selection	8337959
102166237	102166260	2	+	27260156	PANC0813	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.09437213019492963	[216]	[314,255,232,286]	1	hSpCas9	negative selection	8337960
102168633	102168656	2	-	27260156	PANC0813	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.20830133147158691	[341]	[627,471,406,368]	3	hSpCas9	negative selection	8402216
102168629	102168652	2	+	27260156	PANC0813	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.033043613475683645	[511]	[575,531,696,546]	0	hSpCas9	negative selection	8402217
102164927	102164950	2	-	27260156	PANC0813	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.03530670361239663	[220]	[410,270,172,223]	0	hSpCas9	negative selection	8402218
102165203	102165226	2	+	27260156	RDES	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.21970443087562502	[485]	[479,675,686,799]	3	hSpCas9	negative selection	8459209
102165216	102165239	2	-	27260156	RDES	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.30155691988482025	[240]	[193,206,216,292]	-5	hSpCas9	negative selection	8459210
102166237	102166260	2	+	27260156	RDES	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.4157850344019227	[216]	[138,179,171,275]	-6	hSpCas9	negative selection	8459211
102168633	102168656	2	-	27260156	RDES	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.3099030625383953	[341]	[432,516,533,455]	5	hSpCas9	negative selection	8523467
102168629	102168652	2	+	27260156	RDES	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.09596317693985623	[511]	[484,548,579,593]	-2	hSpCas9	negative selection	8523468
102164927	102164950	2	-	27260156	RDES	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.16817301240606508	[220]	[263,218,253,427]	2	hSpCas9	negative selection	8523469
102165203	102165226	2	+	27260156	PC3	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.019764570189917535	[485]	[302,290,985,631]	0	hSpCas9	negative selection	8580460
102165216	102165239	2	-	27260156	PC3	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.022529851551651325	[240]	[188,239,497,138]	0	hSpCas9	negative selection	8580461
102166237	102166260	2	+	27260156	PC3	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.08864013464163634	[216]	[163,240,247,165]	-2	hSpCas9	negative selection	8580462
102168633	102168656	2	-	27260156	PC3	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.39187513589632494	[341]	[308,241,664,694]	7	hSpCas9	negative selection	8644718
102168629	102168652	2	+	27260156	PC3	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.0034439307247938616	[511]	[416,504,828,391]	0	hSpCas9	negative selection	8644719
102164927	102164950	2	-	27260156	PC3	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.22186257831409528	[220]	[119,342,467,211]	5	hSpCas9	negative selection	8644720
102165203	102165226	2	+	27260156	PATU8988T	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.2301841618708454	[485]	[433,491,654,620]	4	hSpCas9	negative selection	8701711
102165216	102165239	2	-	27260156	PATU8988T	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.23162293481702534	[240]	[89,354,139,225]	-4	hSpCas9	negative selection	8701712
102166237	102166260	2	+	27260156	PATU8988T	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.6084920625899299	[216]	[112,209,110,121]	-7	hSpCas9	negative selection	8701713
102168633	102168656	2	-	27260156	PATU8988T	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	-0.021350445263256634	[341]	[419,336,289,250]	0	hSpCas9	negative selection	8765969
102168629	102168652	2	+	27260156	PATU8988T	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.03900642018978402	[511]	[471,465,592,495]	0	hSpCas9	negative selection	8765970
102164927	102164950	2	-	27260156	PATU8988T	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.24372522103832073	[220]	[230,306,145,340]	4	hSpCas9	negative selection	8765971
102165203	102165226	2	+	27260156	T47D	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.1457150902834113	[485]	[649,541,664,655]	3	hSpCas9	negative selection	8822962
102165216	102165239	2	-	27260156	T47D	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.11325754259871001	[240]	[314,333,254,308]	2	hSpCas9	negative selection	8822963
102166237	102166260	2	+	27260156	T47D	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.19265789909253161	[216]	[191,232,202,256]	-4	hSpCas9	negative selection	8822964
102168633	102168656	2	-	27260156	T47D	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.4225770572187803	[341]	[447,559,475,653]	8	hSpCas9	negative selection	8887220
102168629	102168652	2	+	27260156	T47D	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.09383186904618405	[511]	[545,561,506,622]	-2	hSpCas9	negative selection	8887221
102164927	102164950	2	-	27260156	T47D	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.18334365612865344	[220]	[296,283,275,313]	4	hSpCas9	negative selection	8887222
102165203	102165226	2	+	27260156	SU8686	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	-0.029547977412028387	[485]	[386,460,490,573]	0	hSpCas9	negative selection	8944213
102165216	102165239	2	-	27260156	SU8686	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.19579260006229005	[240]	[257,293,181,370]	3	hSpCas9	negative selection	8944214
102166237	102166260	2	+	27260156	SU8686	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.12823462207452363	[216]	[219,124,271,173]	-2	hSpCas9	negative selection	8944215
102168633	102168656	2	-	27260156	SU8686	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.47624362112038243	[341]	[490,454,433,507]	7	hSpCas9	negative selection	9008471
102168629	102168652	2	+	27260156	SU8686	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.15244756936746287	[511]	[464,449,464,440]	-3	hSpCas9	negative selection	9008472
102164927	102164950	2	-	27260156	SU8686	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.1437130927230077	[220]	[228,129,251,396]	2	hSpCas9	negative selection	9008473
102165203	102165226	2	+	27260156	SKES1	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.44275406650407423	[485]	[789,713,619,543]	8	hSpCas9	negative selection	9065464
102165216	102165239	2	-	27260156	SKES1	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.09162304210758443	[240]	[278,256,279,213]	2	hSpCas9	negative selection	9065465
102166237	102166260	2	+	27260156	SKES1	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.527290588866183	[216]	[170,174,71,183]	-8	hSpCas9	negative selection	9065466
102168633	102168656	2	-	27260156	SKES1	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.20553955110577343	[341]	[509,470,355,272]	4	hSpCas9	negative selection	9129722
102168629	102168652	2	+	27260156	SKES1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.21597240107902077	[511]	[539,521,369,356]	-5	hSpCas9	negative selection	9129723
102164927	102164950	2	-	27260156	SKES1	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.04624851256669826	[220]	[304,312,136,180]	1	hSpCas9	negative selection	9129724
102165203	102165226	2	+	27260156	TOV112D	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.0676432813595333	[485]	[595,732,272,499]	1	hSpCas9	negative selection	9186715
102165216	102165239	2	-	27260156	TOV112D	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.06911519451686177	[240]	[316,310,154,165]	-1	hSpCas9	negative selection	9186716
102166237	102166260	2	+	27260156	TOV112D	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.23770290011233275	[216]	[310,308,157,263]	4	hSpCas9	negative selection	9186717
102168633	102168656	2	-	27260156	TOV112D	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.2771239424976958	[341]	[429,469,345,427]	5	hSpCas9	negative selection	9250973
102168629	102168652	2	+	27260156	TOV112D	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.20010047951034643	[511]	[433,572,364,442]	-4	hSpCas9	negative selection	9250974
102164927	102164950	2	-	27260156	TOV112D	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.14569366583824606	[220]	[137,490,242,160]	3	hSpCas9	negative selection	9250975
102165203	102165226	2	+	27260156	TC71	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.0069258602836227215	[485]	[572,450,524,544]	0	hSpCas9	negative selection	9307966
102165216	102165239	2	-	27260156	TC71	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.20033233698816	[240]	[369,270,270,272]	5	hSpCas9	negative selection	9307967
102166237	102166260	2	+	27260156	TC71	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	-0.018500949698833535	[216]	[181,283,271,176]	0	hSpCas9	negative selection	9307968
102168633	102168656	2	-	27260156	TC71	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.2491112905947689	[341]	[504,281,451,505]	6	hSpCas9	negative selection	9372224
102168629	102168652	2	+	27260156	TC71	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.13907207271519895	[511]	[453,453,601,479]	-4	hSpCas9	negative selection	9372225
102164927	102164950	2	-	27260156	TC71	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.19895918014622338	[220]	[257,155,326,349]	5	hSpCas9	negative selection	9372226
102165203	102165226	2	+	27260156	TC32	viability	AAGCAGAAACTACCCGTTGCAGG	IL1R1	ENSG00000115594	0.30169878677533457	[485]	[591,463,555,640]	5	hSpCas9	negative selection	9429217
102165216	102165239	2	-	27260156	TC32	viability	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.04113728749238155	[240]	[202,165,220,362]	0	hSpCas9	negative selection	9429218
102166237	102166260	2	+	27260156	TC32	viability	GCAAGCAATATCCTATTACCCGG	IL1R1	ENSG00000115594	0.08014654110844388	[216]	[229,110,255,302]	1	hSpCas9	negative selection	9429219
102168633	102168656	2	-	27260156	TC32	viability	ACTTCCATTGTCTCATTAGCTGG	IL1R1	ENSG00000115594	0.4872501430787814	[341]	[304,430,626,468]	8	hSpCas9	negative selection	9493475
102168629	102168652	2	+	27260156	TC32	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.09159077599683509	[511]	[548,398,559,559]	1	hSpCas9	negative selection	9493476
102164927	102164950	2	-	27260156	TC32	viability	CTCTTTGTGTTGATGAATCCTGG	IL1R1	ENSG00000115594	0.6110132538725402	[220]	[288,312,355,300]	8	hSpCas9	negative selection	9493477
102164955	102164978	2	+	27869803	HPAFII	viability after 27 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.12209470464848632	[324]	[180,136,NaN]	-1	hSpCas9	negative selection	9571060
102165215	102165238	2	-	27869803	HPAFII	viability after 27 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.07432782236925817	[134]	[83,66,NaN]	0	hSpCas9	negative selection	9571061
102165216	102165239	2	-	27869803	HPAFII	viability after 27 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-1.8565778925016294	[128]	[33,5,NaN]	-8	hSpCas9	negative selection	9571062
102168629	102168652	2	+	27869803	HPAFII	viability after 27 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.04685234598788	[307]	[279,379,NaN]	8	hSpCas9	negative selection	9571063
102164955	102164978	2	+	27869803	HPAFII	viability after 15 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.2297005377067434	[324]	[398,234,NaN]	-3	hSpCas9	negative selection	9653509
102165215	102165238	2	-	27869803	HPAFII	viability after 15 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.09024413697357181	[134]	[196,127,NaN]	1	hSpCas9	negative selection	9653510
102165216	102165239	2	-	27869803	HPAFII	viability after 15 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-1.3638112521121941	[128]	[80,36,NaN]	-8	hSpCas9	negative selection	9653511
102168629	102168652	2	+	27869803	HPAFII	viability after 15 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.33793313472755276	[307]	[455,394,NaN]	4	hSpCas9	negative selection	9653512
102164955	102164978	2	+	27869803	ASPC1	viability after 36 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.47526858771105474	[1007]	[456,863,208]	5	hSpCas9	negative selection	9735958
102165215	102165238	2	-	27869803	ASPC1	viability after 36 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.8287604952510477	[347]	[187,250,204]	7	hSpCas9	negative selection	9735959
102165216	102165239	2	-	27869803	ASPC1	viability after 36 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.30155782576446344	[393]	[160,138,53]	-3	hSpCas9	negative selection	9735960
102168629	102168652	2	+	27869803	ASPC1	viability after 36 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.5009182693524019	[673]	[231,133,143]	-5	hSpCas9	negative selection	9735961
102164955	102164978	2	+	27869803	PATU8988S	viability after 35 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.05226918575063172	[722]	[271,331,NaN]	0	hSpCas9	negative selection	9818407
102165215	102165238	2	-	27869803	PATU8988S	viability after 35 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	-0.48102655053500987	[330]	[100,89,NaN]	-5	hSpCas9	negative selection	9818408
102165216	102165239	2	-	27869803	PATU8988S	viability after 35 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-0.01905712593243558	[272]	[111,104,NaN]	0	hSpCas9	negative selection	9818409
102168629	102168652	2	+	27869803	PATU8988S	viability after 35 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.14783050958429556	[479]	[170,177,NaN]	-1	hSpCas9	negative selection	9818410
102164955	102164978	2	+	27869803	PATU8988S	viability after 31 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	0.3001523333673363	[722]	[383,317,NaN]	4	hSpCas9	negative selection	9900856
102165215	102165238	2	-	27869803	PATU8988S	viability after 31 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	-0.31414100677624746	[330]	[99,113,NaN]	-4	hSpCas9	negative selection	9900857
102165216	102165239	2	-	27869803	PATU8988S	viability after 31 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	0.3786341437723174	[272]	[170,103,NaN]	4	hSpCas9	negative selection	9900858
102168629	102168652	2	+	27869803	PATU8988S	viability after 31 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.20119240575453978	[479]	[180,147,NaN]	-2	hSpCas9	negative selection	9900859
102164955	102164978	2	+	27869803	HPAFII	viability after 35 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.28996086712176367	[324]	[103,168,NaN]	-2	hSpCas9	negative selection	9983305
102165215	102165238	2	-	27869803	HPAFII	viability after 35 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.7201435185852831	[134]	[105,119,NaN]	5	hSpCas9	negative selection	9983306
102165216	102165239	2	-	27869803	HPAFII	viability after 35 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-1.3445771700797573	[128]	[44,3,NaN]	-6	hSpCas9	negative selection	9983307
102168629	102168652	2	+	27869803	HPAFII	viability after 35 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.050339236973769	[307]	[281,368,NaN]	7	hSpCas9	negative selection	9983308
102164955	102164978	2	+	27869803	HPAFII	viability after 31 days	TTGGTTTGTTCCTGCTAAGGTGG	IL1R1	ENSG00000115594	-0.13712737343259687	[324]	[117,217,NaN]	-1	hSpCas9	negative selection	10065754
102165215	102165238	2	-	27869803	HPAFII	viability after 31 days	AGTCCTCCGTCTCCTGCAACGGG	IL1R1	ENSG00000115594	0.325651697886562	[134]	[104,83,NaN]	2	hSpCas9	negative selection	10065755
102165216	102165239	2	-	27869803	HPAFII	viability after 31 days	AAGTCCTCCGTCTCCTGCAACGG	IL1R1	ENSG00000115594	-1.166948369501127	[128]	[59,1,NaN]	-6	hSpCas9	negative selection	10065756
102168629	102168652	2	+	27869803	HPAFII	viability after 31 days	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.2098997366498856	[307]	[362,439,NaN]	8	hSpCas9	negative selection	10065757
102168629	102168652	2	+	28162770	P31FUJ	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.3206493235615601	[215]	[316]	3	hSpCas9	negative selection	10174064
102166179	102166202	2	+	28162770	P31FUJ	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.23943069644600812	[203]	[282]	2	hSpCas9	negative selection	10174065
102168595	102168618	2	+	28162770	P31FUJ	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.23606323138390628	[387]	[536]	2	hSpCas9	negative selection	10174066
102164924	102164947	2	-	28162770	P31FUJ	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.4060386650086204	[218]	[340]	4	hSpCas9	negative selection	10174067
102164958	102164981	2	+	28162770	P31FUJ	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.634303525088276	[749]	[1367]	7	hSpCas9	negative selection	10174068
102165209	102165232	2	+	28162770	P31FUJ	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.6383678152406688	[198]	[363]	7	hSpCas9	negative selection	10174069
102168642	102168665	2	+	28162770	P31FUJ	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	-0.4457959277485768	[152]	[131]	-4	hSpCas9	negative selection	10174070
102171893	102171916	2	-	28162770	P31FUJ	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-0.4789627916837762	[101]	[85]	-4	hSpCas9	negative selection	10174071
102168629	102168652	2	+	28162770	TF1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10343430
102166179	102166202	2	+	28162770	TF1	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10343431
102168595	102168618	2	+	28162770	TF1	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	NaN	[NaN]	[311]	1	hSpCas9	negative selection	10343432
102164924	102164947	2	-	28162770	TF1	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	NaN	[NaN]	[238]	1	hSpCas9	negative selection	10343433
102164958	102164981	2	+	28162770	TF1	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	NaN	[NaN]	[1202]	1	hSpCas9	negative selection	10343434
102165209	102165232	2	+	28162770	TF1	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	NaN	[NaN]	[327]	1	hSpCas9	negative selection	10343435
102168642	102168665	2	+	28162770	TF1	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10343436
102171893	102171916	2	-	28162770	TF1	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10343437
102168629	102168652	2	+	28162770	SKM1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.1419290472704728	[80]	[315]	9	hSpCas9	negative selection	10512796
102166179	102166202	2	+	28162770	SKM1	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.7803428809273871	[54]	[166]	7	hSpCas9	negative selection	10512797
102168595	102168618	2	+	28162770	SKM1	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	-0.028452575489431586	[119]	[207]	0	hSpCas9	negative selection	10512798
102164924	102164947	2	-	28162770	SKM1	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	1.4328122010068198	[43]	[209]	9	hSpCas9	negative selection	10512799
102164958	102164981	2	+	28162770	SKM1	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.18187131112520083	[185]	[372]	1	hSpCas9	negative selection	10512800
102165209	102165232	2	+	28162770	SKM1	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.04473177111453047	[67]	[123]	0	hSpCas9	negative selection	10512801
102168642	102168665	2	+	28162770	SKM1	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	1.1984624045377101	[34]	[141]	9	hSpCas9	negative selection	10512802
102171893	102171916	2	-	28162770	SKM1	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-1.2914869813232257	[17]	[12]	-7	hSpCas9	negative selection	10512803
102168629	102168652	2	+	28162770	SKM1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	1.1419290472704728	[80]	[315]	9	hSpCas9	negative selection	10682162
102166179	102166202	2	+	28162770	SKM1	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.7803428809273871	[54]	[166]	7	hSpCas9	negative selection	10682163
102168595	102168618	2	+	28162770	SKM1	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	-0.028452575489431586	[119]	[207]	0	hSpCas9	negative selection	10682164
102164924	102164947	2	-	28162770	SKM1	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	1.4328122010068198	[43]	[209]	9	hSpCas9	negative selection	10682165
102164958	102164981	2	+	28162770	SKM1	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.18187131112520083	[185]	[372]	1	hSpCas9	negative selection	10682166
102165209	102165232	2	+	28162770	SKM1	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.04473177111453047	[67]	[123]	0	hSpCas9	negative selection	10682167
102168642	102168665	2	+	28162770	SKM1	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	1.1984624045377101	[34]	[141]	9	hSpCas9	negative selection	10682168
102171893	102171916	2	-	28162770	SKM1	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-1.2914869813232257	[17]	[12]	-7	hSpCas9	negative selection	10682169
102168629	102168652	2	+	28162770	PL21	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.7790019156740583	[315]	[235]	6	hSpCas9	negative selection	10851528
102166179	102166202	2	+	28162770	PL21	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	1.482539345190045	[221]	[269]	9	hSpCas9	negative selection	10851529
102168595	102168618	2	+	28162770	PL21	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.3406518881115934	[478]	[263]	3	hSpCas9	negative selection	10851530
102164924	102164947	2	-	28162770	PL21	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	-0.3731881857484328	[246]	[82]	-3	hSpCas9	negative selection	10851531
102164958	102164981	2	+	28162770	PL21	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.4574957080805988	[593]	[354]	4	hSpCas9	negative selection	10851532
102165209	102165232	2	+	28162770	PL21	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.09544223582262704	[199]	[92]	0	hSpCas9	negative selection	10851533
102168642	102168665	2	+	28162770	PL21	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	-0.23157662593615425	[115]	[42]	-2	hSpCas9	negative selection	10851534
102171893	102171916	2	-	28162770	PL21	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	0.2507656875592883	[55]	[28]	2	hSpCas9	negative selection	10851535
102168629	102168652	2	+	28162770	P31FUJ	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.3206493235615601	[215]	[316]	3	hSpCas9	negative selection	11020894
102166179	102166202	2	+	28162770	P31FUJ	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.23943069644600812	[203]	[282]	2	hSpCas9	negative selection	11020895
102168595	102168618	2	+	28162770	P31FUJ	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.23606323138390628	[387]	[536]	2	hSpCas9	negative selection	11020896
102164924	102164947	2	-	28162770	P31FUJ	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.4060386650086204	[218]	[340]	4	hSpCas9	negative selection	11020897
102164958	102164981	2	+	28162770	P31FUJ	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.634303525088276	[749]	[1367]	7	hSpCas9	negative selection	11020898
102165209	102165232	2	+	28162770	P31FUJ	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.6383678152406688	[198]	[363]	7	hSpCas9	negative selection	11020899
102168642	102168665	2	+	28162770	P31FUJ	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	-0.4457959277485768	[152]	[131]	-4	hSpCas9	negative selection	11020900
102171893	102171916	2	-	28162770	P31FUJ	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-0.4789627916837762	[101]	[85]	-4	hSpCas9	negative selection	11020901
102168629	102168652	2	+	28162770	OCIAML5	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.9361372508486954	[129]	[448]	7	hSpCas9	negative selection	11190260
102166179	102166202	2	+	28162770	OCIAML5	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.3385121017966579	[130]	[298]	3	hSpCas9	negative selection	11190261
102168595	102168618	2	+	28162770	OCIAML5	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.6829274705830746	[234]	[680]	6	hSpCas9	negative selection	11190262
102164924	102164947	2	-	28162770	OCIAML5	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.2755214840208552	[145]	[318]	2	hSpCas9	negative selection	11190263
102164958	102164981	2	+	28162770	OCIAML5	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.5150119341924579	[496]	[1281]	4	hSpCas9	negative selection	11190264
102165209	102165232	2	+	28162770	OCIAML5	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.2617023040935774	[194]	[421]	2	hSpCas9	negative selection	11190265
102168642	102168665	2	+	28162770	OCIAML5	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.6362199104454853	[71]	[201]	5	hSpCas9	negative selection	11190266
102171893	102171916	2	-	28162770	OCIAML5	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	0.9666931144658563	[35]	[126]	8	hSpCas9	negative selection	11190267
102168629	102168652	2	+	28162770	EOL1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.47737765135088195	[453]	[332]	4	hSpCas9	negative selection	11359626
102166179	102166202	2	+	28162770	EOL1	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.47363323596309426	[379]	[277]	4	hSpCas9	negative selection	11359627
102168595	102168618	2	+	28162770	EOL1	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	-0.07743804435330892	[726]	[362]	0	hSpCas9	negative selection	11359628
102164924	102164947	2	-	28162770	EOL1	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.24922124319671435	[419]	[262]	2	hSpCas9	negative selection	11359629
102164958	102164981	2	+	28162770	EOL1	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	1.4030539554431682	[805]	[1122]	9	hSpCas9	negative selection	11359630
102165209	102165232	2	+	28162770	EOL1	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.7091587379718491	[273]	[235]	6	hSpCas9	negative selection	11359631
102168642	102168665	2	+	28162770	EOL1	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.7773218183873567	[133]	[120]	6	hSpCas9	negative selection	11359632
102171893	102171916	2	-	28162770	EOL1	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	0.1937344043859235	[77]	[46]	1	hSpCas9	negative selection	11359633
102168629	102168652	2	+	28162770	MOLM13	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.6831950568981466	[378]	[439]	5	hSpCas9	negative selection	11528992
102166179	102166202	2	+	28162770	MOLM13	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.6109240112677425	[354]	[391]	4	hSpCas9	negative selection	11528993
102168595	102168618	2	+	28162770	MOLM13	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.6406149919048056	[628]	[708]	5	hSpCas9	negative selection	11528994
102164924	102164947	2	-	28162770	MOLM13	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	1.4383083909948606	[270]	[530]	9	hSpCas9	negative selection	11528995
102164958	102164981	2	+	28162770	MOLM13	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.7026378590232776	[763]	[898]	5	hSpCas9	negative selection	11528996
102165209	102165232	2	+	28162770	MOLM13	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.6177131769303817	[264]	[293]	4	hSpCas9	negative selection	11528997
102168642	102168665	2	+	28162770	MOLM13	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.3866932986965982	[200]	[189]	3	hSpCas9	negative selection	11528998
102171893	102171916	2	-	28162770	MOLM13	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	1.0330886274443052	[97]	[144]	7	hSpCas9	negative selection	11528999
102168629	102168652	2	+	28162770	HEL	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.5488386931188752	[364]	[341]	4	hSpCas9	negative selection	11698358
102166179	102166202	2	+	28162770	HEL	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.8450470072934724	[278]	[320]	7	hSpCas9	negative selection	11698359
102168595	102168618	2	+	28162770	HEL	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.7997951531716925	[512]	[571]	7	hSpCas9	negative selection	11698360
102164924	102164947	2	-	28162770	HEL	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.11166933927440292	[288]	[199]	0	hSpCas9	negative selection	11698361
102164958	102164981	2	+	28162770	HEL	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.6644933846408783	[723]	[734]	6	hSpCas9	negative selection	11698362
102165209	102165232	2	+	28162770	HEL	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.06403532175088299	[229]	[153]	0	hSpCas9	negative selection	11698363
102168642	102168665	2	+	28162770	HEL	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.2216011331850951	[157]	[117]	1	hSpCas9	negative selection	11698364
102171893	102171916	2	-	28162770	HEL	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	0.5655709714778969	[95]	[90]	5	hSpCas9	negative selection	11698365
102168629	102168652	2	+	28162770	MV411	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.05768225641803315	[319]	[258]	0	hSpCas9	negative selection	11867724
102166179	102166202	2	+	28162770	MV411	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	-0.6779236483244688	[225]	[118]	-5	hSpCas9	negative selection	11867725
102168595	102168618	2	+	28162770	MV411	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.1420348701998646	[439]	[408]	1	hSpCas9	negative selection	11867726
102164924	102164947	2	-	28162770	MV411	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	1.0096865090697493	[180]	[306]	8	hSpCas9	negative selection	11867727
102164958	102164981	2	+	28162770	MV411	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	1.1046973786666934	[551]	[999]	8	hSpCas9	negative selection	11867728
102165209	102165232	2	+	28162770	MV411	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.6996448426521601	[181]	[248]	6	hSpCas9	negative selection	11867729
102168642	102168665	2	+	28162770	MV411	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	1.0129722971457522	[69]	[118]	8	hSpCas9	negative selection	11867730
102171893	102171916	2	-	28162770	MV411	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	0.8478300920735375	[61]	[93]	7	hSpCas9	negative selection	11867731
102168629	102168652	2	+	28162770	MONOMAC1	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.24213755810080023	[162]	[220]	2	hSpCas9	negative selection	12037090
102166179	102166202	2	+	28162770	MONOMAC1	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	0.12295344358631599	[148]	[185]	1	hSpCas9	negative selection	12037091
102168595	102168618	2	+	28162770	MONOMAC1	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.6654596291905114	[230]	[419]	6	hSpCas9	negative selection	12037092
102164924	102164947	2	-	28162770	MONOMAC1	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.7803853049652367	[160]	[316]	7	hSpCas9	negative selection	12037093
102164958	102164981	2	+	28162770	MONOMAC1	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.05957128961480729	[374]	[447]	0	hSpCas9	negative selection	12037094
102165209	102165232	2	+	28162770	MONOMAC1	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.7335417519829666	[148]	[283]	7	hSpCas9	negative selection	12037095
102168642	102168665	2	+	28162770	MONOMAC1	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.3382948859370019	[68]	[99]	3	hSpCas9	negative selection	12037096
102171893	102171916	2	-	28162770	MONOMAC1	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	0.49327865380783087	[43]	[70]	5	hSpCas9	negative selection	12037097
102168629	102168652	2	+	28162770	OCIAML2	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	0.6313911116983477	[57]	[497]	6	hSpCas9	negative selection	12206456
102166179	102166202	2	+	28162770	OCIAML2	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	1.0586232428927074	[43]	[507]	8	hSpCas9	negative selection	12206457
102168595	102168618	2	+	28162770	OCIAML2	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.2363231998576052	[67]	[443]	2	hSpCas9	negative selection	12206458
102164924	102164947	2	-	28162770	OCIAML2	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.8176151433889124	[38]	[380]	7	hSpCas9	negative selection	12206459
102164958	102164981	2	+	28162770	OCIAML2	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.2605534163300387	[99]	[663]	2	hSpCas9	negative selection	12206460
102165209	102165232	2	+	28162770	OCIAML2	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.5396385102116659	[34]	[281]	5	hSpCas9	negative selection	12206461
102168642	102168665	2	+	28162770	OCIAML2	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.7086938742024007	[16]	[153]	7	hSpCas9	negative selection	12206462
102171893	102171916	2	-	28162770	OCIAML2	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	-0.43500591551143986	[9]	[40]	-3	hSpCas9	negative selection	12206463
102168629	102168652	2	+	28162770	OCIAML3	viability	GAGCCCAGCTAATGAGACAATGG	IL1R1	ENSG00000115594	-0.5793608643597616	[97]	[197]	-4	hSpCas9	negative selection	12375822
102166179	102166202	2	+	28162770	OCIAML3	viability	AATGTGGCTGAAAAGCATAGAGG	IL1R1	ENSG00000115594	1.092492886859055	[47]	[308]	8	hSpCas9	negative selection	12375823
102168595	102168618	2	+	28162770	OCIAML3	viability	CAGAGGAAAACAAACCCACAAGG	IL1R1	ENSG00000115594	0.5646241915867904	[113]	[508]	5	hSpCas9	negative selection	12375824
102164924	102164947	2	-	28162770	OCIAML3	viability	TTTGTGTTGATGAATCCTGGAGG	IL1R1	ENSG00000115594	0.04248516103707521	[54]	[170]	0	hSpCas9	negative selection	12375825
102164958	102164981	2	+	28162770	OCIAML3	viability	GTTTGTTCCTGCTAAGGTGGAGG	IL1R1	ENSG00000115594	0.6553887634966689	[154]	[736]	6	hSpCas9	negative selection	12375826
102165209	102165232	2	+	28162770	OCIAML3	viability	AAACTACCCGTTGCAGGAGACGG	IL1R1	ENSG00000115594	0.4775456207008709	[58]	[247]	4	hSpCas9	negative selection	12375827
102168642	102168665	2	+	28162770	OCIAML3	viability	GAGACAATGGAAGTAGACTTGGG	IL1R1	ENSG00000115594	0.005905201862964393	[31]	[96]	0	hSpCas9	negative selection	12375828
102171893	102171916	2	-	28162770	OCIAML3	viability	TAATAGTCTTCCCCTAGCACTGG	IL1R1	ENSG00000115594	1.81316774118171	[22]	[243]	9	hSpCas9	negative selection	12375829