Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:11141
• Symbol:IL1RAPL1
• Description:interleukin 1 receptor accessory protein like 1

DataSource: http://genomecrispr.dkfz.de/#!/results/IL1RAPL1

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
29368930	29368953	X	-	26472758	Jiyoye	viability	GCAGCAGCAGCAACAGAAGATAG	IL1RAPL1	ENSG00000169306	-2.199482190314602	[133]	[21]	-8	hSpCas9	negative selection	21938
29941773	29941796	X	+	26472758	Jiyoye	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.18620503523862342	[168]	[144]	1	hSpCas9	negative selection	77517
29954571	29954594	X	+	26472758	Jiyoye	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.7157759447462433	[347]	[430]	5	hSpCas9	negative selection	77518
29954555	29954578	X	+	26472758	Jiyoye	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.6511009643919625	[227]	[269]	5	hSpCas9	negative selection	77519
29283049	29283072	X	-	26472758	Jiyoye	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	3.1885350950305327	[7]	[54]	9	hSpCas9	negative selection	77520
29396295	29396318	X	+	26472758	Jiyoye	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.4206586108694955	[212]	[214]	3	hSpCas9	negative selection	77521
29668430	29668453	X	-	26472758	Jiyoye	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.34006118564733623	[241]	[230]	2	hSpCas9	negative selection	77522
29941659	29941682	X	+	26472758	Jiyoye	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	-1.149217967018512	[99]	[33]	-7	hSpCas9	negative selection	77523
29941682	29941705	X	-	26472758	Jiyoye	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.19567127631216147	[131]	[113]	1	hSpCas9	negative selection	77524
29396279	29396302	X	+	26472758	Jiyoye	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	77525
29917487	29917510	X	+	26472758	Jiyoye	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.09266475818099407	[290]	[233]	0	hSpCas9	negative selection	77526
29368930	29368953	X	-	26472758	KBM7	viability	GCAGCAGCAGCAACAGAAGATAG	IL1RAPL1	ENSG00000169306	0.2609260381689241	[170,243]	[136,103]	2	hSpCas9	negative selection	213056
29941773	29941796	X	+	26472758	KBM7	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.4983827445135012	[625,480]	[373,355]	5	hSpCas9	negative selection	268635
29954571	29954594	X	+	26472758	KBM7	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.24967344316362694	[1746,1580]	[1033,836]	2	hSpCas9	negative selection	268636
29954555	29954578	X	+	26472758	KBM7	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.49516079054761025	[857,421]	[544,291]	5	hSpCas9	negative selection	268637
29283049	29283072	X	-	26472758	KBM7	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.26094519423688056	[261,298]	[133,182]	2	hSpCas9	negative selection	268638
29396295	29396318	X	+	26472758	KBM7	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.49825979106480134	[940,673]	[683,391]	5	hSpCas9	negative selection	268639
29668430	29668453	X	-	26472758	KBM7	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.017596317115854826	[673,463]	[275,258]	0	hSpCas9	negative selection	268640
29941659	29941682	X	+	26472758	KBM7	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	2.2009971309763317	[139,90]	[490,25]	9	hSpCas9	negative selection	268641
29941682	29941705	X	-	26472758	KBM7	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.763074000368843	[552,478]	[396,422]	8	hSpCas9	negative selection	268642
29396279	29396302	X	+	26472758	KBM7	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	1.0816969781589814	[0,0]	[0,0]	9	hSpCas9	negative selection	268643
29917487	29917510	X	+	26472758	KBM7	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.7387974973755502	[1192,870]	[993,627]	7	hSpCas9	negative selection	268644
29368930	29368953	X	-	26472758	Raji	viability	GCAGCAGCAGCAACAGAAGATAG	IL1RAPL1	ENSG00000169306	0.4444185226511701	[75]	[23]	4	hSpCas9	negative selection	404174
29941773	29941796	X	+	26472758	Raji	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	-0.24831529616900688	[388]	[75]	-2	hSpCas9	negative selection	459753
29954571	29954594	X	+	26472758	Raji	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.33813687862446407	[933]	[273]	3	hSpCas9	negative selection	459754
29954555	29954578	X	+	26472758	Raji	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.30703200105375794	[410]	[117]	3	hSpCas9	negative selection	459755
29283049	29283072	X	-	26472758	Raji	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.5104483929863675	[120]	[39]	5	hSpCas9	negative selection	459756
29396295	29396318	X	+	26472758	Raji	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.6364256633552747	[376]	[135]	6	hSpCas9	negative selection	459757
29668430	29668453	X	-	26472758	Raji	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.9666585103798618	[268]	[121]	8	hSpCas9	negative selection	459758
29941659	29941682	X	+	26472758	Raji	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	0.9665209995337498	[85]	[38]	8	hSpCas9	negative selection	459759
29941682	29941705	X	-	26472758	Raji	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.1590163037889219	[246]	[63]	1	hSpCas9	negative selection	459760
29396279	29396302	X	+	26472758	Raji	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	459761
29917487	29917510	X	+	26472758	Raji	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.5350763354584724	[680]	[228]	5	hSpCas9	negative selection	459762
29368930	29368953	X	-	26472758	K562	viability	GCAGCAGCAGCAACAGAAGATAG	IL1RAPL1	ENSG00000169306	-0.9041037970436414	[183]	[82]	-5	hSpCas9	negative selection	595292
29941773	29941796	X	+	26472758	K562	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.45505317812672286	[527]	[610]	3	hSpCas9	negative selection	650871
29954571	29954594	X	+	26472758	K562	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.7450319586513647	[1349]	[1909]	6	hSpCas9	negative selection	650872
29954555	29954578	X	+	26472758	K562	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.6996807045547889	[503]	[690]	6	hSpCas9	negative selection	650873
29283049	29283072	X	-	26472758	K562	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	1.9092345360768177	[204]	[649]	9	hSpCas9	negative selection	650874
29396295	29396318	X	+	26472758	K562	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.7253253577993063	[684]	[955]	6	hSpCas9	negative selection	650875
29668430	29668453	X	-	26472758	K562	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.5701634783270996	[603]	[756]	4	hSpCas9	negative selection	650876
29941659	29941682	X	+	26472758	K562	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	1.2362908467830467	[88]	[176]	9	hSpCas9	negative selection	650877
29941682	29941705	X	-	26472758	K562	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.050183318817956755	[388]	[339]	0	hSpCas9	negative selection	650878
29396279	29396302	X	+	26472758	K562	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	1.2444187276664467	[0]	[1]	9	hSpCas9	negative selection	650879
29917487	29917510	X	+	26472758	K562	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.9749099876721037	[803]	[1333]	7	hSpCas9	negative selection	650880
29283160	29283183	X	-	26627737	DLD1	viability	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.5467173692031868	[608]	[156,387,291]	5	hSpCas9	negative selection	845464
29396279	29396302	X	+	26627737	DLD1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.332033727856862	[423]	[221,32,63]	-3	hSpCas9	negative selection	845468
29668431	29668454	X	-	26627737	DLD1	viability	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.5077850610105201	[342]	[231,111,116]	5	hSpCas9	negative selection	845472
29917487	29917510	X	+	26627737	DLD1	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.5463906139920476	[349]	[188,233,72]	5	hSpCas9	negative selection	845473
29920071	29920094	X	-	26627737	DLD1	viability	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.63269745821792	[282]	[165,175,79]	6	hSpCas9	negative selection	845474
29941682	29941705	X	-	26627737	DLD1	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.5623690268881345	[1120]	[429,588,533]	5	hSpCas9	negative selection	845476
29283160	29283183	X	-	26627737	GBM cells	viability after 5 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.1984741567445933	[285]	[170,180]	3	hSpCas9	negative selection	927779
29396279	29396302	X	+	26627737	GBM cells	viability after 5 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.17535919997903976	[231]	[137,142]	2	hSpCas9	negative selection	927783
29668431	29668454	X	-	26627737	GBM cells	viability after 5 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.3979031524969888	[120]	[87,82]	6	hSpCas9	negative selection	927787
29917487	29917510	X	+	26627737	GBM cells	viability after 5 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.022488560004218172	[368]	[197,203]	0	hSpCas9	negative selection	927788
29920071	29920094	X	-	26627737	GBM cells	viability after 5 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.21015782426178403	[205]	[81,108]	-3	hSpCas9	negative selection	927789
29941682	29941705	X	-	26627737	GBM cells	viability after 5 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.006458572685018482	[490]	[269,258]	0	hSpCas9	negative selection	927791
29283160	29283183	X	-	26627737	GBM cells	viability after 13 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.6277072817155325	[285]	[252,228]	7	hSpCas9	negative selection	1010094
29396279	29396302	X	+	26627737	GBM cells	viability after 13 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.030003752415513993	[231]	[146,103]	0	hSpCas9	negative selection	1010098
29668431	29668454	X	-	26627737	GBM cells	viability after 13 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.15262843197119602	[120]	[99,50]	2	hSpCas9	negative selection	1010102
29917487	29917510	X	+	26627737	GBM cells	viability after 13 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.20683430888257215	[368]	[315,161]	2	hSpCas9	negative selection	1010103
29920071	29920094	X	-	26627737	GBM cells	viability after 13 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.3281401270492974	[205]	[152,129]	4	hSpCas9	negative selection	1010104
29941682	29941705	X	-	26627737	GBM cells	viability after 13 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.06541248127530941	[490]	[199,298]	-1	hSpCas9	negative selection	1010106
29283160	29283183	X	-	26627737	GBM cells	viability after 21 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.8093562651003645	[285]	[288,256]	7	hSpCas9	negative selection	1092409
29396279	29396302	X	+	26627737	GBM cells	viability after 21 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.21020915449093705	[231]	[161,130]	2	hSpCas9	negative selection	1092413
29668431	29668454	X	-	26627737	GBM cells	viability after 21 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-0.26311110272333704	[120]	[59,49]	-2	hSpCas9	negative selection	1092417
29917487	29917510	X	+	26627737	GBM cells	viability after 21 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.14818270332850625	[368]	[241,203]	1	hSpCas9	negative selection	1092418
29920071	29920094	X	-	26627737	GBM cells	viability after 21 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.7472127444308336	[205]	[202,173]	7	hSpCas9	negative selection	1092419
29941682	29941705	X	-	26627737	GBM cells	viability after 21 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.6026696441945302	[490]	[426,384]	6	hSpCas9	negative selection	1092421
29283160	29283183	X	-	26627737	RPE1	viability after 9 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.9810266311146983	[663]	[415,402]	6	hSpCas9	negative selection	1174724
29396279	29396302	X	+	26627737	RPE1	viability after 9 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.2186555312127491	[941]	[252,253]	-1	hSpCas9	negative selection	1174728
29668431	29668454	X	-	26627737	RPE1	viability after 9 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	1.8242695688823662	[157]	[103,266]	8	hSpCas9	negative selection	1174732
29917487	29917510	X	+	26627737	RPE1	viability after 9 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.6139883013477966	[872]	[316,548]	4	hSpCas9	negative selection	1174733
29920071	29920094	X	-	26627737	RPE1	viability after 9 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.25952226170143144	[898]	[197,282]	-2	hSpCas9	negative selection	1174734
29941682	29941705	X	-	26627737	RPE1	viability after 9 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.1416394564056505	[932]	[278,377]	1	hSpCas9	negative selection	1174736
29283160	29283183	X	-	26627737	RPE1	viability after 12 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.190868172410253	[663]	[398,415]	7	hSpCas9	negative selection	1257039
29396279	29396302	X	+	26627737	RPE1	viability after 12 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.3043939394518276	[941]	[185,224]	-2	hSpCas9	negative selection	1257043
29668431	29668454	X	-	26627737	RPE1	viability after 12 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	1.0224247370777517	[157]	[59,113]	6	hSpCas9	negative selection	1257047
29917487	29917510	X	+	26627737	RPE1	viability after 12 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.5781911330236885	[872]	[287,415]	4	hSpCas9	negative selection	1257048
29920071	29920094	X	-	26627737	RPE1	viability after 12 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.8051538568063512	[898]	[128,147]	-5	hSpCas9	negative selection	1257049
29941682	29941705	X	-	26627737	RPE1	viability after 12 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	1.1156419247914187	[932]	[616,464]	6	hSpCas9	negative selection	1257051
29283160	29283183	X	-	26627737	RPE1	viability after 15 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.0195511099127608	[663]	[448,314]	6	hSpCas9	negative selection	1339354
29396279	29396302	X	+	26627737	RPE1	viability after 15 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.7557279233482959	[941]	[139,174]	-5	hSpCas9	negative selection	1339358
29668431	29668454	X	-	26627737	RPE1	viability after 15 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.8349509303974345	[157]	[66,91]	5	hSpCas9	negative selection	1339362
29917487	29917510	X	+	26627737	RPE1	viability after 15 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.7449090909332886	[872]	[477,351]	4	hSpCas9	negative selection	1339363
29920071	29920094	X	-	26627737	RPE1	viability after 15 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.084871258562087	[898]	[195,281]	0	hSpCas9	negative selection	1339364
29941682	29941705	X	-	26627737	RPE1	viability after 15 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.6609441985432123	[932]	[484,351]	4	hSpCas9	negative selection	1339366
29283160	29283183	X	-	26627737	RPE1	viability after 18 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.4852731592179074	[663]	[681,308]	7	hSpCas9	negative selection	1421669
29396279	29396302	X	+	26627737	RPE1	viability after 18 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.9923742812649082	[941]	[135,118]	-6	hSpCas9	negative selection	1421673
29668431	29668454	X	-	26627737	RPE1	viability after 18 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	1.1731273533558617	[157]	[85,106]	6	hSpCas9	negative selection	1421677
29917487	29917510	X	+	26627737	RPE1	viability after 18 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.7224545296534489	[872]	[409,365]	4	hSpCas9	negative selection	1421678
29920071	29920094	X	-	26627737	RPE1	viability after 18 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.18302435421916344	[898]	[175,253]	-1	hSpCas9	negative selection	1421679
29941682	29941705	X	-	26627737	RPE1	viability after 18 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.4798270137967849	[932]	[427,268]	3	hSpCas9	negative selection	1421681
29283160	29283183	X	-	26627737	HeLa	viability after 8 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.8252488928222033	[270]	[180,131,300]	6	hSpCas9	negative selection	1503984
29396279	29396302	X	+	26627737	HeLa	viability after 8 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.04050579580773789	[330]	[144,154,143]	0	hSpCas9	negative selection	1503988
29668431	29668454	X	-	26627737	HeLa	viability after 8 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-0.27393975303104406	[280]	[259,60,22]	-3	hSpCas9	negative selection	1503992
29917487	29917510	X	+	26627737	HeLa	viability after 8 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.04409173821932444	[392]	[212,102,217]	0	hSpCas9	negative selection	1503993
29920071	29920094	X	-	26627737	HeLa	viability after 8 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.6435667407324511	[401]	[165,42,136]	-6	hSpCas9	negative selection	1503994
29941682	29941705	X	-	26627737	HeLa	viability after 8 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.3679405251374259	[1247]	[321,339,567]	-4	hSpCas9	negative selection	1503996
29283160	29283183	X	-	26627737	HeLa	viability after 12 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.5771905427988682	[270]	[205,151,145]	5	hSpCas9	negative selection	1586299
29396279	29396302	X	+	26627737	HeLa	viability after 12 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.20356961733851042	[330]	[123,151,76]	-2	hSpCas9	negative selection	1586303
29668431	29668454	X	-	26627737	HeLa	viability after 12 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.7282788251607026	[280]	[223,126,233]	6	hSpCas9	negative selection	1586307
29917487	29917510	X	+	26627737	HeLa	viability after 12 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.8243481223322922	[392]	[387,161,328]	6	hSpCas9	negative selection	1586308
29920071	29920094	X	-	26627737	HeLa	viability after 12 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.6596624160664393	[401]	[80,140,88]	-5	hSpCas9	negative selection	1586309
29941682	29941705	X	-	26627737	HeLa	viability after 12 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.13715702722808598	[1247]	[218,531,641]	-1	hSpCas9	negative selection	1586311
29283160	29283183	X	-	26627737	HeLa	viability after 15 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.5728498700529082	[270]	[183,204,97]	4	hSpCas9	negative selection	1668614
29396279	29396302	X	+	26627737	HeLa	viability after 15 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.9937335762045962	[330]	[81,50,69]	-7	hSpCas9	negative selection	1668618
29668431	29668454	X	-	26627737	HeLa	viability after 15 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.6361779313649621	[280]	[165,159,209]	5	hSpCas9	negative selection	1668622
29917487	29917510	X	+	26627737	HeLa	viability after 15 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.18331771388072585	[392]	[139,157,252]	1	hSpCas9	negative selection	1668623
29920071	29920094	X	-	26627737	HeLa	viability after 15 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.008081749674164484	[401]	[58,177,259]	0	hSpCas9	negative selection	1668624
29941682	29941705	X	-	26627737	HeLa	viability after 15 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.20725176921711386	[1247]	[249,495,587]	-2	hSpCas9	negative selection	1668626
29283160	29283183	X	-	26627737	HeLa	viability after 18 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.6065569711156019	[270]	[133,165,97]	5	hSpCas9	negative selection	1750929
29396279	29396302	X	+	26627737	HeLa	viability after 18 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.965544017999044	[330]	[56,42,69]	-7	hSpCas9	negative selection	1750933
29668431	29668454	X	-	26627737	HeLa	viability after 18 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.5957020698191771	[280]	[102,130,209]	5	hSpCas9	negative selection	1750937
29917487	29917510	X	+	26627737	HeLa	viability after 18 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.18984368768339413	[392]	[88,138,252]	1	hSpCas9	negative selection	1750938
29920071	29920094	X	-	26627737	HeLa	viability after 18 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.04252882123145857	[401]	[47,150,259]	0	hSpCas9	negative selection	1750939
29941682	29941705	X	-	26627737	HeLa	viability after 18 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.2084361222604234	[1247]	[169,406,587]	-2	hSpCas9	negative selection	1750941
29283160	29283183	X	-	26627737	HCT116	viability after 6 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.37743675306330876	[571]	[65,70]	-2	hSpCas9	negative selection	1833244
29396279	29396302	X	+	26627737	HCT116	viability after 6 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.3336120559610634	[345]	[132,32]	1	hSpCas9	negative selection	1833248
29668431	29668454	X	-	26627737	HCT116	viability after 6 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-1.5855389588438462	[380]	[8,25]	-7	hSpCas9	negative selection	1833252
29917487	29917510	X	+	26627737	HCT116	viability after 6 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.16996165227459736	[565]	[141,76]	0	hSpCas9	negative selection	1833253
29920071	29920094	X	-	26627737	HCT116	viability after 6 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.45765712559730654	[595]	[89,149]	2	hSpCas9	negative selection	1833254
29941682	29941705	X	-	26627737	HCT116	viability after 6 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.09573616239335969	[1188]	[269,160]	0	hSpCas9	negative selection	1833256
29283160	29283183	X	-	26627737	HCT116	viability after 8 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.5081337904469658	[398]	[142,201,118]	-6	hSpCas9	negative selection	1915559
29396279	29396302	X	+	26627737	HCT116	viability after 8 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.20673865356628482	[305]	[234,195,153]	2	hSpCas9	negative selection	1915563
29668431	29668454	X	-	26627737	HCT116	viability after 8 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-0.411026173591741	[315]	[118,170,102]	-5	hSpCas9	negative selection	1915567
29917487	29917510	X	+	26627737	HCT116	viability after 8 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	-0.060198377567784456	[405]	[326,208,110]	0	hSpCas9	negative selection	1915568
29920071	29920094	X	-	26627737	HCT116	viability after 8 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.38118619754603095	[276]	[241,143,210]	4	hSpCas9	negative selection	1915569
29941682	29941705	X	-	26627737	HCT116	viability after 8 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.378300523921267	[570]	[496,365,365]	4	hSpCas9	negative selection	1915571
29283160	29283183	X	-	26627737	HCT116	viability after 9 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.6260532467270508	[571]	[266,210]	4	hSpCas9	negative selection	1997874
29396279	29396302	X	+	26627737	HCT116	viability after 9 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	1.0081921071929951	[345]	[320,78]	7	hSpCas9	negative selection	1997878
29668431	29668454	X	-	26627737	HCT116	viability after 9 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.542200414073978	[380]	[79,201]	4	hSpCas9	negative selection	1997882
29917487	29917510	X	+	26627737	HCT116	viability after 9 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.8415210840239263	[565]	[138,374]	6	hSpCas9	negative selection	1997883
29920071	29920094	X	-	26627737	HCT116	viability after 9 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.153217105857944	[595]	[122,158]	-1	hSpCas9	negative selection	1997884
29941682	29941705	X	-	26627737	HCT116	viability after 9 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.5597937590166002	[1188]	[758,237]	4	hSpCas9	negative selection	1997886
29283160	29283183	X	-	26627737	HCT116	viability after 12 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.2041368696387501	[398]	[113,221,216]	-2	hSpCas9	negative selection	2080189
29396279	29396302	X	+	26627737	HCT116	viability after 12 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.2563083626023249	[305]	[176,126,95]	-3	hSpCas9	negative selection	2080193
29668431	29668454	X	-	26627737	HCT116	viability after 12 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-0.9783532477113311	[315]	[40,97,117]	-8	hSpCas9	negative selection	2080197
29917487	29917510	X	+	26627737	HCT116	viability after 12 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	-0.23323474941056793	[405]	[141,180,224]	-2	hSpCas9	negative selection	2080198
29920071	29920094	X	-	26627737	HCT116	viability after 12 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.0948134935755801	[276]	[140,155,111]	-1	hSpCas9	negative selection	2080199
29941682	29941705	X	-	26627737	HCT116	viability after 12 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.45993580212778584	[570]	[464,426,341]	4	hSpCas9	negative selection	2080201
29283160	29283183	X	-	26627737	HCT116	viability after 15 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.26680693421155854	[398]	[174,163,229]	-3	hSpCas9	negative selection	2162504
29396279	29396302	X	+	26627737	HCT116	viability after 15 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.3752133279510475	[305]	[230,126,60]	-4	hSpCas9	negative selection	2162508
29668431	29668454	X	-	26627737	HCT116	viability after 15 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-0.7118649019406015	[315]	[108,97,124]	-6	hSpCas9	negative selection	2162512
29917487	29917510	X	+	26627737	HCT116	viability after 15 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	-0.03584339702987721	[405]	[169,249,254]	0	hSpCas9	negative selection	2162513
29920071	29920094	X	-	26627737	HCT116	viability after 15 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.3364734621919223	[276]	[289,168,154]	3	hSpCas9	negative selection	2162514
29941682	29941705	X	-	26627737	HCT116	viability after 15 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.593960617457392	[570]	[623,415,460]	5	hSpCas9	negative selection	2162516
29283160	29283183	X	-	26627737	HCT116	viability after 18 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.4283781523455614	[398]	[93,120,219]	-4	hSpCas9	negative selection	2244819
29396279	29396302	X	+	26627737	HCT116	viability after 18 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.3449125385485917	[305]	[209,175,177]	3	hSpCas9	negative selection	2244823
29668431	29668454	X	-	26627737	HCT116	viability after 18 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-0.7941427627404626	[315]	[69,80,114]	-6	hSpCas9	negative selection	2244827
29917487	29917510	X	+	26627737	HCT116	viability after 18 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	-0.46938934687983114	[405]	[107,123,196]	-4	hSpCas9	negative selection	2244828
29920071	29920094	X	-	26627737	HCT116	viability after 18 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.16706230655870669	[276]	[163,93,198]	1	hSpCas9	negative selection	2244829
29941682	29941705	X	-	26627737	HCT116	viability after 18 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.6245948238326821	[570]	[455,385,437]	5	hSpCas9	negative selection	2244831
29240307	29240330	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGTCTCCCAG	IL1RAPL1	ENSG00000169306	-0.17877550951857135	[78,119]	[17,20]	0	dCas9-VP64	positive selection	2386105
29368420	29368443	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCACTGCACTCCAGCCTGGTGG	IL1RAPL1	ENSG00000169306	1.049956001898007	[3,11]	[2,3]	4	dCas9-VP64	positive selection	2389144
29706211	29706234	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGAGCTACAAGATGAGATTTGG	IL1RAPL1	ENSG00000169306	0.9275899236952089	[95,36]	[24,29]	4	dCas9-VP64	positive selection	2389502
29939911	29939934	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGTAGTGGCGCGATCTCAG	IL1RAPL1	ENSG00000169306	3.1722237697093507	[103,9]	[210,6]	8	dCas9-VP64	positive selection	2392255
28829749	28829772	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTTTCACCATGTTGGCCGGG	IL1RAPL1	ENSG00000169306	0.051094447397205506	[27,110]	[6,24]	0	dCas9-VP64	positive selection	2397840
29320529	29320552	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATTTGGGAGGCTGAGGCAGGTAG	IL1RAPL1	ENSG00000169306	1.0311422578945828	[46,428]	[158,53]	4	dCas9-VP64	positive selection	2400089
28895624	28895647	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTAAGTTGGCACCAGAGTTGGGG	IL1RAPL1	ENSG00000169306	-0.9245438828404792	[27,124]	[11,4]	-5	dCas9-VP64	positive selection	2406904
28930751	28930774	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTACTCGGGAGACTGAGGCAGG	IL1RAPL1	ENSG00000169306	-0.7498462491276636	[113,13]	[10,3]	-4	dCas9-VP64	positive selection	2408592
29575567	29575590	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATCCACCCTCAATGTGGGTGGG	IL1RAPL1	ENSG00000169306	0.8900610346402346	[116,84]	[39,41]	3	dCas9-VP64	positive selection	2415541
29596110	29596133	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCATGCTGTTTTGGTGACTATGG	IL1RAPL1	ENSG00000169306	1.0480995924872216	[118,451]	[10,260]	4	dCas9-VP64	positive selection	2417745
29240101	29240124	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TATTCACAGGTTCTGGGGATTAG	IL1RAPL1	ENSG00000169306	-1.6123727665609728	[211,22]	[8,6]	-8	dCas9-VP64	positive selection	2418194
29703370	29703393	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCTCACTCTGTCTCCCAGGCCAG	IL1RAPL1	ENSG00000169306	-0.22926698104333687	[120,197]	[15,43]	-1	dCas9-VP64	positive selection	2418645
29088426	29088449	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCCAAGGAGG	IL1RAPL1	ENSG00000169306	0.21234444010885142	[57,122]	[21,23]	1	dCas9-VP64	positive selection	2422539
29373914	29373937	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGTTTGAGACCAGCCTCAG	IL1RAPL1	ENSG00000169306	-1.6026008362934678	[306,558]	[26,34]	-8	dCas9-VP64	positive selection	2428458
28736154	28736177	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCACGCCCAG	IL1RAPL1	ENSG00000169306	1.2080578617800355	[188,10]	[73,23]	5	dCas9-VP64	positive selection	2430197
29265783	29265806	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATGAGTTCATGTCCTTTGTGGG	IL1RAPL1	ENSG00000169306	0.027217556958692324	[823,313]	[189,57]	0	dCas9-VP64	positive selection	2432648
29415560	29415583	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCGTGCCACCACGCCCGG	IL1RAPL1	ENSG00000169306	2.643483847646077	[13,290]	[2,439]	8	dCas9-VP64	positive selection	2433879
28658255	28658278	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCCCAGGCTGGAGTGCAGAGG	IL1RAPL1	ENSG00000169306	0.9977856233970179	[9,4]	[4,0]	4	dCas9-VP64	positive selection	2435958
28587410	28587433	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACACAACCCCTGCTGTTTGG	IL1RAPL1	ENSG00000169306	-2.448375491314687	[486,863]	[26,26]	-9	dCas9-VP64	positive selection	2443702
28587377	28587400	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGAGGAGAGCTAGGACCCAGG	IL1RAPL1	ENSG00000169306	-3.4897223099280064	[68,533]	[6,2]	-9	dCas9-VP64	positive selection	2443703
28587434	28587457	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACATAGCAGTACTGTACAAGG	IL1RAPL1	ENSG00000169306	-0.2481697448828707	[142,73]	[26,10]	-1	dCas9-VP64	positive selection	2443704
29262568	29262591	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCTCTTGAACCCAAG	IL1RAPL1	ENSG00000169306	0.7055876385115556	[3,484]	[1,182]	3	dCas9-VP64	positive selection	2452071
28656931	28656954	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATGGCATGAACCCCGG	IL1RAPL1	ENSG00000169306	-0.6383309141464126	[28,8]	[1,1]	-3	dCas9-VP64	positive selection	2452449
29507478	29507501	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCACCCTTGACCTCCCGGG	IL1RAPL1	ENSG00000169306	1.9771960985489354	[459,700]	[75,968]	7	dCas9-VP64	positive selection	2453493
29597202	29597225	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAATGGCGCGATATCGG	IL1RAPL1	ENSG00000169306	-1.2298112070102956	[12,28]	[1,1]	-7	dCas9-VP64	positive selection	2456294
29197782	29197805	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCGCAACCTCCGCCTCCCTGG	IL1RAPL1	ENSG00000169306	-0.34420875558774866	[84,317]	[37,31]	-2	dCas9-VP64	positive selection	2460553
28792693	28792716	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATGGCGTGAACCCGGG	IL1RAPL1	ENSG00000169306	1.2888057383448681	[173,387]	[82,225]	5	dCas9-VP64	positive selection	2465693
28786275	28786298	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGATGGGGTTTCACTATGTTGGG	IL1RAPL1	ENSG00000169306	-1.0998643350942743	[293,186]	[24,23]	-6	dCas9-VP64	positive selection	2468189
29208584	29208607	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCTGTAGTCCCAGCTACTCTGG	IL1RAPL1	ENSG00000169306	0.4848717924049799	[259,492]	[140,88]	2	dCas9-VP64	positive selection	2468773
28765061	28765084	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTGAGAACATGTGGTGTTCGG	IL1RAPL1	ENSG00000169306	-1.1334071955764224	[258,107]	[23,10]	-6	dCas9-VP64	positive selection	2468912
29415694	29415717	X	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAACCACCGCGCCCAG	IL1RAPL1	ENSG00000169306	0.09960352240682058	[3,22]	[3,0]	0	dCas9-VP64	positive selection	2472523
29795561	29795584	X	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGAGG	IL1RAPL1	ENSG00000169306	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473447
29240307	29240330	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGTCTCCCAG	IL1RAPL1	ENSG00000169306	1.3499530185057784	[84,70]	[54,73]	7	dCas9-VP64	positive selection	2481360
29368420	29368443	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCACTGCACTCCAGCCTGGTGG	IL1RAPL1	ENSG00000169306	0.3100958641524221	[17,26]	[5,11]	2	dCas9-VP64	positive selection	2484399
29706211	29706234	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGAGCTACAAGATGAGATTTGG	IL1RAPL1	ENSG00000169306	0.0345862241759054	[177,72]	[58,25]	0	dCas9-VP64	positive selection	2484757
29939911	29939934	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGTAGTGGCGCGATCTCAG	IL1RAPL1	ENSG00000169306	0.8627698723325049	[50,145]	[36,76]	6	dCas9-VP64	positive selection	2487510
28829749	28829772	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTTTCACCATGTTGGCCGGG	IL1RAPL1	ENSG00000169306	-0.16706931973118405	[70,280]	[30,67]	-2	dCas9-VP64	positive selection	2493095
29320529	29320552	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATTTGGGAGGCTGAGGCAGGTAG	IL1RAPL1	ENSG00000169306	0.6350691816100226	[174,241]	[44,161]	5	dCas9-VP64	positive selection	2495344
28895624	28895647	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTAAGTTGGCACCAGAGTTGGGG	IL1RAPL1	ENSG00000169306	1.4514715903805788	[109,48]	[33,106]	7	dCas9-VP64	positive selection	2502159
28930751	28930774	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTACTCGGGAGACTGAGGCAGG	IL1RAPL1	ENSG00000169306	-1.0734520873599889	[20,56]	[6,3]	-8	dCas9-VP64	positive selection	2503847
29575567	29575590	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATCCACCCTCAATGTGGGTGGG	IL1RAPL1	ENSG00000169306	-0.7792138181914499	[21,44]	[6,4]	-7	dCas9-VP64	positive selection	2510796
29596110	29596133	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCATGCTGTTTTGGTGACTATGG	IL1RAPL1	ENSG00000169306	0.32664799356599117	[40,68]	[18,24]	2	dCas9-VP64	positive selection	2513000
29240101	29240124	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TATTCACAGGTTCTGGGGATTAG	IL1RAPL1	ENSG00000169306	-0.08120075685248235	[80,101]	[38,16]	0	dCas9-VP64	positive selection	2513449
29703370	29703393	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCTCACTCTGTCTCCCAGGCCAG	IL1RAPL1	ENSG00000169306	-0.22012594312438807	[153,72]	[52,11]	-2	dCas9-VP64	positive selection	2513900
29088426	29088449	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCCAAGGAGG	IL1RAPL1	ENSG00000169306	-0.9329704115466368	[100,219]	[26,25]	-8	dCas9-VP64	positive selection	2517794
29373914	29373937	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGTTTGAGACCAGCCTCAG	IL1RAPL1	ENSG00000169306	0.9241793657004961	[25,55]	[22,26]	6	dCas9-VP64	positive selection	2523713
28736154	28736177	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCACGCCCAG	IL1RAPL1	ENSG00000169306	1.0270683763310697	[166,152]	[69,140]	6	dCas9-VP64	positive selection	2525452
29265783	29265806	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATGAGTTCATGTCCTTTGTGGG	IL1RAPL1	ENSG00000169306	1.4038075420975922	[289,245]	[108,347]	7	dCas9-VP64	positive selection	2527903
29415560	29415583	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCGTGCCACCACGCCCGG	IL1RAPL1	ENSG00000169306	0.7224579133223353	[33,61]	[16,32]	5	dCas9-VP64	positive selection	2529134
28658255	28658278	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCCCAGGCTGGAGTGCAGAGG	IL1RAPL1	ENSG00000169306	-0.1814090993543942	[50,40]	[18,6]	-2	dCas9-VP64	positive selection	2531213
28587410	28587433	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACACAACCCCTGCTGTTTGG	IL1RAPL1	ENSG00000169306	-0.0135108073852801	[393,427]	[170,96]	0	dCas9-VP64	positive selection	2538957
28587377	28587400	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGAGGAGAGCTAGGACCCAGG	IL1RAPL1	ENSG00000169306	-0.3739752354287307	[364,64]	[84,25]	-4	dCas9-VP64	positive selection	2538958
28587434	28587457	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACATAGCAGTACTGTACAAGG	IL1RAPL1	ENSG00000169306	1.632603826319237	[245,281]	[42,477]	8	dCas9-VP64	positive selection	2538959
29262568	29262591	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCTCTTGAACCCAAG	IL1RAPL1	ENSG00000169306	-0.4319067453035411	[83,67]	[14,20]	-4	dCas9-VP64	positive selection	2547326
28656931	28656954	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATGGCATGAACCCCGG	IL1RAPL1	ENSG00000169306	4.9253728466972815	[108,193]	[3088,18]	9	dCas9-VP64	positive selection	2547704
29507478	29507501	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCACCCTTGACCTCCCGGG	IL1RAPL1	ENSG00000169306	-0.13896238492127178	[332,394]	[87,125]	-1	dCas9-VP64	positive selection	2548748
29597202	29597225	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAATGGCGCGATATCGG	IL1RAPL1	ENSG00000169306	0.49065487898162874	[21,35]	[18,6]	4	dCas9-VP64	positive selection	2551549
29197782	29197805	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCGCAACCTCCGCCTCCCTGG	IL1RAPL1	ENSG00000169306	-0.7693251235982987	[139,201]	[37,26]	-7	dCas9-VP64	positive selection	2555808
28792693	28792716	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATGGCGTGAACCCGGG	IL1RAPL1	ENSG00000169306	0.12656923196241077	[264,270]	[122,69]	1	dCas9-VP64	positive selection	2560948
28786275	28786298	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGATGGGGTTTCACTATGTTGGG	IL1RAPL1	ENSG00000169306	-0.2266176027776325	[165,194]	[50,48]	-2	dCas9-VP64	positive selection	2563444
29208584	29208607	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCTGTAGTCCCAGCTACTCTGG	IL1RAPL1	ENSG00000169306	0.2857588864060996	[349,998]	[76,442]	2	dCas9-VP64	positive selection	2564028
28765061	28765084	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTGAGAACATGTGGTGTTCGG	IL1RAPL1	ENSG00000169306	-0.007859909983208867	[140,86]	[47,26]	0	dCas9-VP64	positive selection	2564167
29415694	29415717	X	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAACCACCGCGCCCAG	IL1RAPL1	ENSG00000169306	-0.3804364072538059	[231,140]	[55,37]	-4	dCas9-VP64	positive selection	2567778
29795561	29795584	X	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGAGG	IL1RAPL1	ENSG00000169306	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568702
29396296	29396319	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.5400262573582819	[3,3]	[3,5]	9	hSpCas9	positive selection	2995320
29917488	29917511	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.038209410088124826	[3,3]	[2,3]	0	hSpCas9	positive selection	2995321
29396281	29396304	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTATCCATCTCACTGACAGTGGG	IL1RAPL1	ENSG00000169306	-0.5548732838793256	[3,3]	[3,0]	-7	hSpCas9	positive selection	2995322
29283170	29283193	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCCTGTAGCAATGTTGGCCGG	IL1RAPL1	ENSG00000169306	0.029925406667574678	[4,4]	[5,2]	0	hSpCas9	positive selection	2995323
29396296	29396319	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.3290421506076908	[3,3]	[3,2]	6	hSpCas9	positive selection	3063178
29917488	29917511	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	1.0710310192927894	[3,3]	[3,7]	9	hSpCas9	positive selection	3063179
29396281	29396304	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTATCCATCTCACTGACAGTGGG	IL1RAPL1	ENSG00000169306	-0.4422790996712819	[3,3]	[3,0]	-6	hSpCas9	positive selection	3063180
29283170	29283193	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCCTGTAGCAATGTTGGCCGG	IL1RAPL1	ENSG00000169306	0.25690157610413694	[4,4]	[4,3]	4	hSpCas9	positive selection	3063181
28789411	28789434		-	24336571	A375	resistance to PLX after 7 days	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	-0.42672737377269865	[6,9]	[5,5]	-9	hSpCas9	positive selection	3120876
29283124	29283147		-	24336571	A375	resistance to PLX after 7 days	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.047767075959844085	[33,34]	[33,32]	-1	hSpCas9	positive selection	3120877
29282935	29282958		+	24336571	A375	resistance to PLX after 7 days	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.2403028919969501	[21,24]	[18,19]	-7	hSpCas9	positive selection	3120878
28789411	28789434		-	24336571	A375	resistance to PLX after 14 days	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.19439870535889736	[7,6]	[2,3]	2	hSpCas9	positive selection	3178669
29283124	29283147		-	24336571	A375	resistance to PLX after 14 days	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	1.3204891610340508	[21,29]	[27,32]	8	hSpCas9	positive selection	3178670
29282935	29282958		+	24336571	A375	resistance to PLX after 14 days	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-1.1610490496310584	[30,25]	[5,4]	-9	hSpCas9	positive selection	3178671
28789411	28789434		-	24336571	A375	viability after 7 days	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	-0.1479930424764263	[9]	[6,9]	-2	hSpCas9	negative selection	3236462
29283124	29283147		-	24336571	A375	viability after 7 days	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.20462807061933574	[31]	[33,34]	3	hSpCas9	negative selection	3236463
29282935	29282958		+	24336571	A375	viability after 7 days	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.2620916973071321	[19]	[21,24]	4	hSpCas9	negative selection	3236464
28789411	28789434		-	24336571	A375	viability after 14 days	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	-0.29716518745391096	[9]	[7,6]	-4	hSpCas9	negative selection	3294255
29283124	29283147		-	24336571	A375	viability after 14 days	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.20143275204914923	[31]	[21,29]	-2	hSpCas9	negative selection	3294256
29282935	29282958		+	24336571	A375	viability after 14 days	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.5478712486763958	[19]	[30,25]	7	hSpCas9	negative selection	3294257
29282935	29282958	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.600654783681737	[231,231]	[0,0]	-4	hSpCas9	positive selection	3374136
29396279	29396302	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-1.5174608481553384	[437,437]	[0,0]	-8	hSpCas9	positive selection	3374137
28789359	28789382	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.9353981165584727	[79,79]	[0,0]	4	hSpCas9	positive selection	3374138
29396295	29396318	X	+	26780180	HT29	viability (Avana library 4 designs)	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.982732077328305	[]	[]	4	hSpCas9	negative selection	3432687
29917487	29917510	X	+	26780180	HT29	viability (Avana library 4 designs)	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	1.02281526688225	[]	[]	4	hSpCas9	negative selection	3432688
29396280	29396303	X	+	26780180	HT29	viability (Avana library 4 designs)	GTATCCATCTCACTGACAGTGGG	IL1RAPL1	ENSG00000169306	0.883350548253055	[]	[]	3	hSpCas9	negative selection	3432689
29283170	29283193	X	-	26780180	HT29	viability (Avana library 4 designs)	TGTCCTGTAGCAATGTTGGCCGG	IL1RAPL1	ENSG00000169306	0.391306201578544	[]	[]	1	hSpCas9	negative selection	3432690
29396280	29396303	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTATCCATCTCACTGACAGTGGG	IL1RAPL1	ENSG00000169306	0.465662851343356	[]	[]	0	hSpCas9	negative selection	3518949
29917487	29917510	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	3.69809165806342	[]	[]	6	hSpCas9	negative selection	3518950
29396295	29396318	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	5.57870807637441	[]	[]	8	hSpCas9	negative selection	3518951
29283170	29283193	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCTGTAGCAATGTTGGCCGG	IL1RAPL1	ENSG00000169306	4.33493366345425	[]	[]	7	hSpCas9	negative selection	3518952
29283174	29283197	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCAACATTGCTACAGGACAGTGG	IL1RAPL1	ENSG00000169306	4.55029257015772	[]	[]	7	hSpCas9	negative selection	3518953
29283049	29283072	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	4.97358221323961	[]	[]	8	hSpCas9	negative selection	3518954
29396280	29396303	X	+	26780180	A375	viability (Avana lentiGuide)	GTATCCATCTCACTGACAGTGGG	IL1RAPL1	ENSG00000169306	-0.608346531034481	[]	[]	-1	hSpCas9	negative selection	3627608
29917487	29917510	X	+	26780180	A375	viability (Avana lentiGuide)	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	-4.98900305956852	[]	[]	-8	hSpCas9	negative selection	3627609
29396295	29396318	X	+	26780180	A375	viability (Avana lentiGuide)	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	-2.45926150550132	[]	[]	-4	hSpCas9	negative selection	3627610
29283170	29283193	X	-	26780180	A375	viability (Avana lentiGuide)	TGTCCTGTAGCAATGTTGGCCGG	IL1RAPL1	ENSG00000169306	2.97975305390534	[]	[]	3	hSpCas9	negative selection	3627611
29283174	29283197	X	+	26780180	A375	viability (Avana lentiGuide)	CCAACATTGCTACAGGACAGTGG	IL1RAPL1	ENSG00000169306	-5.96913269180204	[]	[]	-8	hSpCas9	negative selection	3627612
29283049	29283072	X	-	26780180	A375	viability (Avana lentiGuide)	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	2.59151696380301	[]	[]	2	hSpCas9	negative selection	3627613
29396280	29396303	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTATCCATCTCACTGACAGTGGG	IL1RAPL1	ENSG00000169306	-0.15870929600596698	[5]	[4,4]	-3	hSpCas9	positive selection	3736267
29917487	29917510	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	-0.01106012969955214	[5]	[5,5]	0	hSpCas9	positive selection	3736268
29396295	29396318	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.06736356448621784	[4]	[5,3]	1	hSpCas9	positive selection	3736269
29283170	29283193	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCTGTAGCAATGTTGGCCGG	IL1RAPL1	ENSG00000169306	0.29318988616988056	[5]	[7,6]	8	hSpCas9	positive selection	3736270
29283174	29283197	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAACATTGCTACAGGACAGTGG	IL1RAPL1	ENSG00000169306	0.20917651074654078	[4]	[5,4]	6	hSpCas9	positive selection	3736271
29283049	29283072	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.3786422168757602	[4]	[5,6]	9	hSpCas9	positive selection	3736272
29396280	29396303	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTATCCATCTCACTGACAGTGGG	IL1RAPL1	ENSG00000169306	0.14858118741853557	[5]	[5,4]	3	hSpCas9	positive selection	3844874
29917487	29917510	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.10146877687916793	[5]	[4,4]	2	hSpCas9	positive selection	3844875
29396295	29396318	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.11926516908939044	[5]	[5,3]	2	hSpCas9	positive selection	3844876
29283170	29283193	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCTGTAGCAATGTTGGCCGG	IL1RAPL1	ENSG00000169306	0.18632738853149003	[6]	[5,5]	4	hSpCas9	positive selection	3844877
29283174	29283197	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAACATTGCTACAGGACAGTGG	IL1RAPL1	ENSG00000169306	0.36115771155230375	[5]	[5,5]	9	hSpCas9	positive selection	3844878
29283049	29283072	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	-0.19799198910484445	[4]	[1,4]	-3	hSpCas9	positive selection	3844879
29396378	29396401	X	+	26780180	A375	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.170952271198303	[]	[]	0	hSpCas9	negative selection	3950839
29396279	29396302	X	+	26780180	A375	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.788296074810086	[]	[]	3	hSpCas9	negative selection	3950840
28789411	28789434	X	-	26780180	A375	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.219471472836507	[]	[]	0	hSpCas9	negative selection	3950841
28789359	28789382	X	-	26780180	A375	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.904762334726307	[]	[]	4	hSpCas9	negative selection	3950842
29283124	29283147	X	-	26780180	A375	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.283164716016379	[]	[]	0	hSpCas9	negative selection	3950843
29282935	29282958	X	+	26780180	A375	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	1.44401589661858	[]	[]	8	hSpCas9	negative selection	3950844
29396378	29396401	X	+	26780180	HT29	viability (GeCKOv2 library)	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.92062870798594	[]	[]	4	hSpCas9	negative selection	4058805
29396279	29396302	X	+	26780180	HT29	viability (GeCKOv2 library)	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.0182107761655314	[]	[]	0	hSpCas9	negative selection	4058806
28789411	28789434	X	-	26780180	HT29	viability (GeCKOv2 library)	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.544190794930889	[]	[]	1	hSpCas9	negative selection	4058807
28789359	28789382	X	-	26780180	HT29	viability (GeCKOv2 library)	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.420709854875911	[]	[]	1	hSpCas9	negative selection	4058808
29283124	29283147	X	-	26780180	HT29	viability (GeCKOv2 library)	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.897527409918567	[]	[]	4	hSpCas9	negative selection	4058809
29282935	29282958	X	+	26780180	HT29	viability (GeCKOv2 library)	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	1.28507239789301	[]	[]	6	hSpCas9	negative selection	4058810
28789411	28789434	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	-0.1843825979508987	[3]	[1,1]	-4	hSpCas9	positive selection	4144514
29283124	29283147	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.3692891211666659	[5]	[4,4]	8	hSpCas9	positive selection	4144515
29282935	29282958	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.0867771917560366	[4]	[3,2]	-2	hSpCas9	positive selection	4144516
28789411	28789434	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	-0.06086969340517363	[3]	[1,2,1,0]	-1	hSpCas9	positive selection	4208536
29283124	29283147	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.8622412841055971	[4]	[1,4,2,3]	5	hSpCas9	positive selection	4208537
29282935	29282958	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.02044546945122408	[4]	[3,1,2,0]	0	hSpCas9	positive selection	4208538
29283124	29283147	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.3179981722650966	[2]	[3,1]	6	hSpCas9	positive selection	4276734
29396378	29396401	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.09341449565304083	[1]	[2,0]	-2	hSpCas9	positive selection	4276735
28789411	28789434	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.6673498762745167	[2]	[4,3]	9	hSpCas9	positive selection	4276736
29282935	29282958	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.07781951791013136	[3]	[3,2]	1	hSpCas9	positive selection	4340992
29396279	29396302	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.301224554863773	[4]	[3,4]	6	hSpCas9	positive selection	4340993
28789359	28789382	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.28109617706486356	[2]	[2,0]	-5	hSpCas9	positive selection	4340994
29283124	29283146	X	-	27760321	OCIAML3	viability	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.26562567284132504	[389,360]	[196,305]	-3	hSpCas9	negative selection	4409434
29283160	29283182	X	-	27760321	OCIAML3	viability	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.06075830674413818	[294,287]	[144,359]	0	hSpCas9	negative selection	4409435
29396379	29396401	X	+	27760321	OCIAML3	viability	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.7408118968067996	[410,387]	[440,628]	8	hSpCas9	negative selection	4409436
29396432	29396454	X	-	27760321	OCIAML3	viability	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.7455643023645906	[161,131]	[186,197]	8	hSpCas9	negative selection	4409437
29920071	29920093	X	-	27760321	OCIAML3	viability	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.048585500872078025	[217,271]	[177,199]	0	hSpCas9	negative selection	4409438
29283124	29283146	X	-	27760321	OCIAML2	viability	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.17654090789865495	[389,360]	[254,286]	-2	hSpCas9	negative selection	4492897
29283160	29283182	X	-	27760321	OCIAML2	viability	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.7043248564462609	[294,287]	[347,433]	8	hSpCas9	negative selection	4492898
29396379	29396401	X	+	27760321	OCIAML2	viability	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.31810566527802664	[410,387]	[341,483]	4	hSpCas9	negative selection	4492899
29396432	29396454	X	-	27760321	OCIAML2	viability	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.9489559037110714	[161,131]	[211,249]	9	hSpCas9	negative selection	4492900
29920071	29920093	X	-	27760321	OCIAML2	viability	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.440934861208399	[217,271]	[239,314]	6	hSpCas9	negative selection	4492901
29283124	29283146	X	-	27760321	MV411	viability	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.42775261673458453	[389,360]	[276,417]	3	hSpCas9	negative selection	4576360
29283160	29283182	X	-	27760321	MV411	viability	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.1227870294742597	[294,287]	[494,306]	7	hSpCas9	negative selection	4576361
29396379	29396401	X	+	27760321	MV411	viability	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.1033085874825736	[410,387]	[291,175]	0	hSpCas9	negative selection	4576362
29396432	29396454	X	-	27760321	MV411	viability	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.4039281147745506	[161,131]	[0,317]	3	hSpCas9	negative selection	4576363
29920071	29920093	X	-	27760321	MV411	viability	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.6725696663839379	[217,271]	[349,126]	5	hSpCas9	negative selection	4576364
29283124	29283146	X	-	27760321	HL60	viability	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.20526654427839358	[389,360]	[268,262]	-2	hSpCas9	negative selection	4659823
29283160	29283182	X	-	27760321	HL60	viability	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.1264923346219002	[294,287]	[274,781]	9	hSpCas9	negative selection	4659824
29396379	29396401	X	+	27760321	HL60	viability	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.12864020316451164	[410,387]	[307,288]	-1	hSpCas9	negative selection	4659825
29396432	29396454	X	-	27760321	HL60	viability	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.7516037390880492	[161,131]	[205,195]	8	hSpCas9	negative selection	4659826
29920071	29920093	X	-	27760321	HL60	viability	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.15050894568612982	[217,271]	[166,198]	-2	hSpCas9	negative selection	4659827
29283124	29283146	X	-	27760321	HT1080	viability	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	1.4261449235533032	[360,281]	[263,431]	7	hSpCas9	negative selection	4743286
29283160	29283182	X	-	27760321	HT1080	viability	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.9448189123472432	[287,224]	[179,214]	5	hSpCas9	negative selection	4743287
29396379	29396401	X	+	27760321	HT1080	viability	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.6358196494181949	[387,302]	[168,262]	3	hSpCas9	negative selection	4743288
29396432	29396454	X	-	27760321	HT1080	viability	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.5010342334158844	[131,102]	[102,25]	2	hSpCas9	negative selection	4743289
29920071	29920093	X	-	27760321	HT1080	viability	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.5478767146641077	[271,211]	[170,107]	3	hSpCas9	negative selection	4743290
29283124	29283146	X	-	27760321	HT29	viability after 7 days	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.20897974146905895	[360,281]	[513,264,316]	-3	hSpCas9	negative selection	4826749
29283160	29283182	X	-	27760321	HT29	viability after 7 days	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.11422101987025096	[287,224]	[301,265,343]	-2	hSpCas9	negative selection	4826750
29396379	29396401	X	+	27760321	HT29	viability after 7 days	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.04533959386122168	[387,302]	[415,540,412]	0	hSpCas9	negative selection	4826751
29396432	29396454	X	-	27760321	HT29	viability after 7 days	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.40323778431199475	[131,102]	[161,114,312]	6	hSpCas9	negative selection	4826752
29920071	29920093	X	-	27760321	HT29	viability after 7 days	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.2982696675730111	[271,211]	[212,351,189]	-4	hSpCas9	negative selection	4826753
29283124	29283146	X	-	27760321	HT29	viability after 25 days	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.02454382407920344	[360,281]	[339,447,288]	0	hSpCas9	negative selection	4910212
29283160	29283182	X	-	27760321	HT29	viability after 25 days	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.04760375428711311	[287,224]	[296,308,238]	0	hSpCas9	negative selection	4910213
29396379	29396401	X	+	27760321	HT29	viability after 25 days	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.2548433503842806	[387,302]	[347,303,802]	2	hSpCas9	negative selection	4910214
29396432	29396454	X	-	27760321	HT29	viability after 25 days	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.6725633611038581	[131,102]	[234,177,228]	7	hSpCas9	negative selection	4910215
29920071	29920093	X	-	27760321	HT29	viability after 25 days	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.505503728347148	[271,211]	[234,216,121]	-5	hSpCas9	negative selection	4910216
29283124	29283146	X	-	27760321	HT29	viability after 22 days	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.24148222481427895	[360,281]	[301,382,257]	-3	hSpCas9	negative selection	4993675
29283160	29283182	X	-	27760321	HT29	viability after 22 days	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.07848803892700368	[287,224]	[224,340,277]	-1	hSpCas9	negative selection	4993676
29396379	29396401	X	+	27760321	HT29	viability after 22 days	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.3296296520660811	[387,302]	[198,399,918]	3	hSpCas9	negative selection	4993677
29396432	29396454	X	-	27760321	HT29	viability after 22 days	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.3415952866550427	[131,102]	[141,116,258]	3	hSpCas9	negative selection	4993678
29920071	29920093	X	-	27760321	HT29	viability after 22 days	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.23431285069240326	[271,211]	[161,362,189]	-2	hSpCas9	negative selection	4993679
29283124	29283146	X	-	27760321	HT29	viability after 19 days	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	-0.14840690211261648	[360,281]	[427,160,412]	-1	hSpCas9	negative selection	5077138
29283160	29283182	X	-	27760321	HT29	viability after 19 days	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.3788366535169016	[287,224]	[281,530,322]	3	hSpCas9	negative selection	5077139
29396379	29396401	X	+	27760321	HT29	viability after 19 days	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.032843013457703005	[387,302]	[475,307,383]	0	hSpCas9	negative selection	5077140
29396432	29396454	X	-	27760321	HT29	viability after 19 days	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.369373218704552	[131,102]	[310,102,122]	3	hSpCas9	negative selection	5077141
29920071	29920093	X	-	27760321	HT29	viability after 19 days	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.27989779797811987	[271,211]	[207,363,113]	-3	hSpCas9	negative selection	5077142
29283124	29283146	X	-	27760321	HT29	viability after 16 days	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.28747314727397977	[360,281]	[447,395,474]	3	hSpCas9	negative selection	5160601
29283160	29283182	X	-	27760321	HT29	viability after 16 days	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.36010988393505083	[287,224]	[341,426,331]	4	hSpCas9	negative selection	5160602
29396379	29396401	X	+	27760321	HT29	viability after 16 days	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.2741110182266378	[387,302]	[350,247,797]	3	hSpCas9	negative selection	5160603
29396432	29396454	X	-	27760321	HT29	viability after 16 days	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	-0.6933010590130366	[131,102]	[30,47,160]	-6	hSpCas9	negative selection	5160604
29920071	29920093	X	-	27760321	HT29	viability after 16 days	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.3291668463490768	[271,211]	[310,233,109]	-4	hSpCas9	negative selection	5160605
29283124	29283146	X	-	27760321	HT29	viability after 13 days	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.33635082257037163	[360,281]	[393,515,500]	4	hSpCas9	negative selection	5244064
29283160	29283182	X	-	27760321	HT29	viability after 13 days	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.1476728984957119	[287,224]	[348,244,214]	-2	hSpCas9	negative selection	5244065
29396379	29396401	X	+	27760321	HT29	viability after 13 days	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.6782755196589112	[387,302]	[250,225,272]	-6	hSpCas9	negative selection	5244066
29396432	29396454	X	-	27760321	HT29	viability after 13 days	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.4592468164987078	[131,102]	[271,102,186]	6	hSpCas9	negative selection	5244067
29920071	29920093	X	-	27760321	HT29	viability after 13 days	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-1.0202001553696085	[271,211]	[72,248,95]	-7	hSpCas9	negative selection	5244068
29283124	29283146	X	-	27760321	HT29	viability after 10 days	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.34476803749083806	[360,281]	[234,846,457]	4	hSpCas9	negative selection	5327527
29283160	29283182	X	-	27760321	HT29	viability after 10 days	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.03036481034697741	[287,224]	[208,264,461]	0	hSpCas9	negative selection	5327528
29396379	29396401	X	+	27760321	HT29	viability after 10 days	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.5229855731871397	[387,302]	[268,281,347]	-6	hSpCas9	negative selection	5327529
29396432	29396454	X	-	27760321	HT29	viability after 10 days	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	0.26975902623289527	[131,102]	[161,131,233]	3	hSpCas9	negative selection	5327530
29920071	29920093	X	-	27760321	HT29	viability after 10 days	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.5999280967985758	[271,211]	[142,264,191]	-6	hSpCas9	negative selection	5327531
29283124	29283146	X	-	27760321	MOLM13	viability	CTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	1.7278820488577664	[389,360]	[192,1134]	9	hSpCas9	negative selection	5410990
29283160	29283182	X	-	27760321	MOLM13	viability	AATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.6312979467411353	[294,287]	[418,115]	4	hSpCas9	negative selection	5410991
29396379	29396401	X	+	27760321	MOLM13	viability	ATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	1.6325026029847853	[410,387]	[349,996]	9	hSpCas9	negative selection	5410992
29396432	29396454	X	-	27760321	MOLM13	viability	AGTCCATACCTTGTACCAAAGG	IL1RAPL1	ENSG00000169306	1.2215257790555478	[161,131]	[132,242]	8	hSpCas9	negative selection	5410993
29920071	29920093	X	-	27760321	MOLM13	viability	CGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	1.463536593180534	[217,271]	[218,527]	8	hSpCas9	negative selection	5410994
29283124	29283147	X	-	27260156	BXPC3	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.3912249418567795	[307]	[407,377,480,424]	8	hSpCas9	negative selection	5549194
29396378	29396401	X	+	27260156	BXPC3	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.03541253549189638	[188]	[186,183,189,256]	0	hSpCas9	negative selection	5549195
28789411	28789434	X	-	27260156	BXPC3	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.44020449644983445	[431]	[549,563,632,723]	8	hSpCas9	negative selection	5549196
29282935	29282958	X	+	27260156	BXPC3	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.21748048311784485	[824]	[567,772,728,932]	-5	hSpCas9	negative selection	5613452
29396279	29396302	X	+	27260156	BXPC3	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.007800272338698067	[1101]	[997,1228,1176,1188]	0	hSpCas9	negative selection	5613453
28789359	28789382	X	-	27260156	BXPC3	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.2115249115948994	[359]	[330,336,279,350]	-5	hSpCas9	negative selection	5613454
29283124	29283147	X	-	27260156	A673	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.49492756530930515	[307]	[539,608,479,450]	9	hSpCas9	negative selection	5670445
29396378	29396401	X	+	27260156	A673	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.07868481659811044	[188]	[273,249,157,282]	2	hSpCas9	negative selection	5670446
28789411	28789434	X	-	27260156	A673	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.27107626296192233	[431]	[630,515,658,703]	6	hSpCas9	negative selection	5670447
29282935	29282958	X	+	27260156	A673	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.3869925676423465	[824]	[923,778,818,510]	-7	hSpCas9	negative selection	5734703
29396279	29396302	X	+	27260156	A673	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.09291500788024654	[1101]	[1387,1205,1289,1084]	-2	hSpCas9	negative selection	5734704
28789359	28789382	X	-	27260156	A673	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.3910680453806401	[359]	[361,353,325,275]	-7	hSpCas9	negative selection	5734705
29283124	29283147	X	-	27260156	A375	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.1485149069747551	[307]	[387,450,504,271]	2	hSpCas9	negative selection	5791696
29396378	29396401	X	+	27260156	A375	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.20843971287131402	[188]	[325,346,200,168]	3	hSpCas9	negative selection	5791697
28789411	28789434	X	-	27260156	A375	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.488492215277766	[431]	[655,1044,758,446]	7	hSpCas9	negative selection	5791698
29282935	29282958	X	+	27260156	A375	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.1259092801046824	[824]	[717,964,889,956]	-2	hSpCas9	negative selection	5855954
29396279	29396302	X	+	27260156	A375	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.039661615532939676	[1101]	[1293,1284,1372,1077]	0	hSpCas9	negative selection	5855955
28789359	28789382	X	-	27260156	A375	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.05239605341512488	[359]	[468,517,422,353]	0	hSpCas9	negative selection	5855956
29283124	29283147	X	-	27260156	COLO741	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.4795423475416658	[307]	[663,421,566]	8	hSpCas9	negative selection	5912947
29396378	29396401	X	+	27260156	COLO741	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.027330940231146572	[188]	[177,311,216]	0	hSpCas9	negative selection	5912948
28789411	28789434	X	-	27260156	COLO741	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.2761463749887651	[431]	[873,495,651]	6	hSpCas9	negative selection	5912949
29282935	29282958	X	+	27260156	COLO741	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.23352584364962026	[824]	[988,971,745]	-5	hSpCas9	negative selection	5977205
29396279	29396302	X	+	27260156	COLO741	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.08808114134518519	[1101]	[1130,1555,1271]	-2	hSpCas9	negative selection	5977206
28789359	28789382	X	-	27260156	COLO741	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.17302858711664093	[359]	[384,453,383]	-4	hSpCas9	negative selection	5977207
29283124	29283147	X	-	27260156	CAL120	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.35346296421904	[307]	[541,405,527]	5	hSpCas9	negative selection	6034198
29396378	29396401	X	+	27260156	CAL120	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.09990414008017279	[188]	[114,332,194]	-1	hSpCas9	negative selection	6034199
28789411	28789434	X	-	27260156	CAL120	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.4361175587792839	[431]	[536,831,782]	6	hSpCas9	negative selection	6034200
29282935	29282958	X	+	27260156	CAL120	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.04275259363544115	[824]	[1075,1126,801]	0	hSpCas9	negative selection	6098456
29396279	29396302	X	+	27260156	CAL120	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.24220302530257976	[1101]	[1272,963,1255]	-4	hSpCas9	negative selection	6098457
28789359	28789382	X	-	27260156	CAL120	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.22954332928104146	[359]	[815,375,428]	3	hSpCas9	negative selection	6098458
29283124	29283147	X	-	27260156	CADOES1	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.726251944634761	[307]	[432,477,502,481]	9	hSpCas9	negative selection	6155449
29396378	29396401	X	+	27260156	CADOES1	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.040307303778654546	[188]	[212,106,179,183]	0	hSpCas9	negative selection	6155450
28789411	28789434	X	-	27260156	CADOES1	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.38938297610073036	[431]	[627,455,460,560]	6	hSpCas9	negative selection	6155451
29282935	29282958	X	+	27260156	CADOES1	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.10467651086456109	[824]	[715,769,667,699]	-2	hSpCas9	negative selection	6219707
29396279	29396302	X	+	27260156	CADOES1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.20958525992288424	[1101]	[888,1008,751,895]	-4	hSpCas9	negative selection	6219708
28789359	28789382	X	-	27260156	CADOES1	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.01993705829335285	[359]	[363,398,280,312]	0	hSpCas9	negative selection	6219709
29283124	29283147	X	-	27260156	EWS502	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.7638744505923782	[307]	[592,534,483,599]	9	hSpCas9	negative selection	6276700
29396378	29396401	X	+	27260156	EWS502	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.07894425082208234	[188]	[142,217,181,220]	-1	hSpCas9	negative selection	6276701
28789411	28789434	X	-	27260156	EWS502	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.3739067562352933	[431]	[503,751,616,493]	6	hSpCas9	negative selection	6276702
29282935	29282958	X	+	27260156	EWS502	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.008407695600625709	[824]	[921,674,992,885]	0	hSpCas9	negative selection	6340958
29396279	29396302	X	+	27260156	EWS502	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.10332551460790662	[1101]	[910,970,1216,1284]	-2	hSpCas9	negative selection	6340959
28789359	28789382	X	-	27260156	EWS502	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.14392229837192216	[359]	[202,339,298,569]	-3	hSpCas9	negative selection	6340960
29283124	29283147	X	-	27260156	EW8	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.5244550781485628	[307]	[239,511,321,354]	8	hSpCas9	negative selection	6397951
29396378	29396401	X	+	27260156	EW8	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.2510446197675196	[188]	[229,178,151,177]	4	hSpCas9	negative selection	6397952
28789411	28789434	X	-	27260156	EW8	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.5512740954904549	[431]	[771,315,526,460]	8	hSpCas9	negative selection	6397953
29282935	29282958	X	+	27260156	EW8	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.0873479265793854	[824]	[925,633,436,583]	-2	hSpCas9	negative selection	6462209
29396279	29396302	X	+	27260156	EW8	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.07456591031222093	[1101]	[808,1129,689,784]	-1	hSpCas9	negative selection	6462210
28789359	28789382	X	-	27260156	EW8	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.24760786625218412	[359]	[334,210,227,220]	-5	hSpCas9	negative selection	6462211
29283124	29283147	X	-	27260156	CORL105	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.6661625887535616	[307]	[546,483,722,558]	9	hSpCas9	negative selection	6519202
29396378	29396401	X	+	27260156	CORL105	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.5772776870451998	[188]	[256,331,382,353]	9	hSpCas9	negative selection	6519203
28789411	28789434	X	-	27260156	CORL105	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.4573979615101855	[431]	[640,733,739,666]	8	hSpCas9	negative selection	6519204
29282935	29282958	X	+	27260156	CORL105	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.00166826595924352	[824]	[928,940,1136,877]	0	hSpCas9	negative selection	6583460
29396279	29396302	X	+	27260156	CORL105	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.0006796879094965735	[1101]	[1233,1163,1614,1200]	0	hSpCas9	negative selection	6583461
28789359	28789382	X	-	27260156	CORL105	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.08410376342300674	[359]	[384,324,504,392]	-1	hSpCas9	negative selection	6583462
29283124	29283147	X	-	27260156	HS294T	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.828553423324156	[307]	[129,209,297,215]	9	hSpCas9	negative selection	6640453
29396378	29396401	X	+	27260156	HS294T	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.09480805772229384	[188]	[68,44,97,60]	-1	hSpCas9	negative selection	6640454
28789411	28789434	X	-	27260156	HS294T	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.42467083254430826	[431]	[234,174,245,243]	6	hSpCas9	negative selection	6640455
29282935	29282958	X	+	27260156	HS294T	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.11360097445594408	[824]	[315,237,555,261]	1	hSpCas9	negative selection	6704711
29396279	29396302	X	+	27260156	HS294T	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.1612119832277803	[1101]	[313,450,375,386]	-2	hSpCas9	negative selection	6704712
28789359	28789382	X	-	27260156	HS294T	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.0714355586386125	[359]	[105,120,94,225]	-1	hSpCas9	negative selection	6704713
29283124	29283147	X	-	27260156	HCC44	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.3329491192598031	[307]	[651,444,319,335]	5	hSpCas9	negative selection	6761704
29396378	29396401	X	+	27260156	HCC44	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.02003883654943328	[188]	[139,212,206,271]	0	hSpCas9	negative selection	6761705
28789411	28789434	X	-	27260156	HCC44	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.471507454490146	[431]	[715,662,824,535]	7	hSpCas9	negative selection	6761706
29282935	29282958	X	+	27260156	HCC44	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.15361222511621286	[824]	[645,741,1081,913]	-3	hSpCas9	negative selection	6825962
29396279	29396302	X	+	27260156	HCC44	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.16138195836586156	[1101]	[1137,814,1252,1304]	-3	hSpCas9	negative selection	6825963
28789359	28789382	X	-	27260156	HCC44	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.09168450974600639	[359]	[172,225,549,600]	-1	hSpCas9	negative selection	6825964
29283124	29283147	X	-	27260156	G402	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.9720953093693026	[307]	[537,543,914,900]	9	hSpCas9	negative selection	6882955
29396378	29396401	X	+	27260156	G402	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.39796357192827403	[188]	[524,154,219,335]	5	hSpCas9	negative selection	6882956
28789411	28789434	X	-	27260156	G402	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.505744294800755	[431]	[893,710,725,681]	6	hSpCas9	negative selection	6882957
29282935	29282958	X	+	27260156	G402	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.05206900744697629	[824]	[776,1279,945,871]	0	hSpCas9	negative selection	6947213
29396279	29396302	X	+	27260156	G402	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.024421614621951804	[1101]	[1364,1563,1126,1250]	0	hSpCas9	negative selection	6947214
28789359	28789382	X	-	27260156	G402	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.47631040381784306	[359]	[303,259,358,332]	-5	hSpCas9	negative selection	6947215
29283124	29283147	X	-	27260156	L33	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.45252041302991775	[307]	[418,170,248,452]	8	hSpCas9	negative selection	7004206
29396378	29396401	X	+	27260156	L33	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.4032112934798693	[188]	[214,57,57,120]	-7	hSpCas9	negative selection	7004207
28789411	28789434	X	-	27260156	L33	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.4974953699059407	[431]	[562,258,366,660]	8	hSpCas9	negative selection	7004208
29282935	29282958	X	+	27260156	L33	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.3210762085960908	[824]	[656,341,381,542]	-6	hSpCas9	negative selection	7068464
29396279	29396302	X	+	27260156	L33	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.11035305017621133	[1101]	[1083,423,557,1073]	-2	hSpCas9	negative selection	7068465
28789359	28789382	X	-	27260156	L33	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.3339607787521026	[359]	[230,119,209,285]	-7	hSpCas9	negative selection	7068466
29283124	29283147	X	-	27260156	K562	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.7990963711964354	[307]	[372,676,588,285]	8	hSpCas9	negative selection	7125457
29396378	29396401	X	+	27260156	K562	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.30275530533952444	[188]	[184,189,345,113]	4	hSpCas9	negative selection	7125458
28789411	28789434	X	-	27260156	K562	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	1.0130785765311816	[431]	[1040,1019,438,641]	9	hSpCas9	negative selection	7125459
29282935	29282958	X	+	27260156	K562	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.1098942440173577	[824]	[1038,743,623,372]	-1	hSpCas9	negative selection	7189715
29396279	29396302	X	+	27260156	K562	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.09387948380118338	[1101]	[1440,708,782,776]	-1	hSpCas9	negative selection	7189716
28789359	28789382	X	-	27260156	K562	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.45138739262131844	[359]	[209,261,263,200]	-5	hSpCas9	negative selection	7189717
29283124	29283147	X	-	27260156	HT29	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.31619907826330435	[307]	[427,596,319,517]	6	hSpCas9	negative selection	7246708
29396378	29396401	X	+	27260156	HT29	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.09405452578889784	[188]	[254,223,360,149]	1	hSpCas9	negative selection	7246709
28789411	28789434	X	-	27260156	HT29	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.5939617107725699	[431]	[754,891,735,787]	9	hSpCas9	negative selection	7246710
29282935	29282958	X	+	27260156	HT29	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.06676881835148585	[824]	[757,1076,836,1124]	-1	hSpCas9	negative selection	7310966
29396279	29396302	X	+	27260156	HT29	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.006687166711770276	[1101]	[1585,1085,1324,1325]	0	hSpCas9	negative selection	7310967
28789359	28789382	X	-	27260156	HT29	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.10405792473390835	[359]	[537,349,372,373]	-2	hSpCas9	negative selection	7310968
29283124	29283147	X	-	27260156	MHHES1	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.49924342860297055	[307]	[676,448,465,397]	8	hSpCas9	negative selection	7367959
29396378	29396401	X	+	27260156	MHHES1	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.11667179866774147	[188]	[281,204,242,198]	2	hSpCas9	negative selection	7367960
28789411	28789434	X	-	27260156	MHHES1	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.6131790522483461	[431]	[888,620,920,574]	9	hSpCas9	negative selection	7367961
29282935	29282958	X	+	27260156	MHHES1	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.11108955753584071	[824]	[944,1169,771,629]	-2	hSpCas9	negative selection	7432217
29396279	29396302	X	+	27260156	MHHES1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.0043908023046503875	[1101]	[1148,1404,1310,1095]	0	hSpCas9	negative selection	7432218
28789359	28789382	X	-	27260156	MHHES1	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.22911386615508855	[359]	[746,593,346,289]	4	hSpCas9	negative selection	7432219
29283124	29283147	X	-	27260156	MEWO	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.5885084110322913	[307]	[475,444,386]	9	hSpCas9	negative selection	7489210
29396378	29396401	X	+	27260156	MEWO	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.1695487614797393	[188]	[184,155,135]	-4	hSpCas9	negative selection	7489211
28789411	28789434	X	-	27260156	MEWO	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.27009500867128045	[431]	[513,522,429]	6	hSpCas9	negative selection	7489212
29282935	29282958	X	+	27260156	MEWO	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.5154418116851666	[824]	[526,386,703]	-8	hSpCas9	negative selection	7553468
29396279	29396302	X	+	27260156	MEWO	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.050684735833175676	[1101]	[1197,972,1057]	1	hSpCas9	negative selection	7553469
28789359	28789382	X	-	27260156	MEWO	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.01283391046677701	[359]	[265,351,386]	0	hSpCas9	negative selection	7553470
29283124	29283147	X	-	27260156	LNCAPCLONEFGC	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.6400220089710075	[307]	[477,301,570,415]	8	hSpCas9	negative selection	7610461
29396378	29396401	X	+	27260156	LNCAPCLONEFGC	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.36682924222835167	[188]	[187,164,346,205]	6	hSpCas9	negative selection	7610462
28789411	28789434	X	-	27260156	LNCAPCLONEFGC	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.609647327877396	[431]	[428,475,661,841]	8	hSpCas9	negative selection	7610463
29282935	29282958	X	+	27260156	LNCAPCLONEFGC	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.10505395520821958	[824]	[538,767,801,683]	-2	hSpCas9	negative selection	7674719
29396279	29396302	X	+	27260156	LNCAPCLONEFGC	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.1790706463932934	[1101]	[1076,1045,1503,954]	3	hSpCas9	negative selection	7674720
28789359	28789382	X	-	27260156	LNCAPCLONEFGC	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.1530109994301284	[359]	[303,248,382,252]	-2	hSpCas9	negative selection	7674721
29283124	29283147	X	-	27260156	PANC0327	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.5497316965877104	[307]	[293,195,688,440]	7	hSpCas9	negative selection	7731712
29396378	29396401	X	+	27260156	PANC0327	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.4614781639029474	[188]	[254,183,374,118]	6	hSpCas9	negative selection	7731713
28789411	28789434	X	-	27260156	PANC0327	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.18486763862388456	[431]	[503,268,529,468]	2	hSpCas9	negative selection	7731714
29282935	29282958	X	+	27260156	PANC0327	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.4625267016577409	[824]	[679,370,492,615]	-6	hSpCas9	negative selection	7795970
29396279	29396302	X	+	27260156	PANC0327	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.0029166994736442575	[1101]	[606,982,1348,937]	0	hSpCas9	negative selection	7795971
28789359	28789382	X	-	27260156	PANC0327	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.005973673003097202	[359]	[368,177,448,310]	0	hSpCas9	negative selection	7795972
29283124	29283147	X	-	27260156	NCIH2009	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.500088997845112	[307]	[950,413,530]	7	hSpCas9	negative selection	7852963
29396378	29396401	X	+	27260156	NCIH2009	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.046534397901227376	[188]	[395,220,225]	0	hSpCas9	negative selection	7852964
28789411	28789434	X	-	27260156	NCIH2009	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	1.0626073287155795	[431]	[1321,1206,1263]	9	hSpCas9	negative selection	7852965
29282935	29282958	X	+	27260156	NCIH2009	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.13049831674745938	[824]	[1445,986,802]	-2	hSpCas9	negative selection	7917221
29396279	29396302	X	+	27260156	NCIH2009	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.017798098117719707	[1101]	[1637,1407,1538]	0	hSpCas9	negative selection	7917222
28789359	28789382	X	-	27260156	NCIH2009	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.01708154190795752	[359]	[527,300,670]	0	hSpCas9	negative selection	7917223
29283124	29283147	X	-	27260156	NCIH1373	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.8528322964549806	[307]	[681,585,289,255]	8	hSpCas9	negative selection	7974214
29396378	29396401	X	+	27260156	NCIH1373	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.18585837847333853	[188]	[432,195,277,20]	1	hSpCas9	negative selection	7974215
28789411	28789434	X	-	27260156	NCIH1373	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	1.4032292216878794	[431]	[1857,1164,1312,224]	9	hSpCas9	negative selection	7974216
29282935	29282958	X	+	27260156	NCIH1373	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.2549526484509096	[824]	[1660,1001,942,233]	2	hSpCas9	negative selection	8038472
29396279	29396302	X	+	27260156	NCIH1373	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.1446001037966187	[1101]	[1539,1296,1290,357]	1	hSpCas9	negative selection	8038473
28789359	28789382	X	-	27260156	NCIH1373	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.21602748592340273	[359]	[547,693,376,59]	2	hSpCas9	negative selection	8038474
29283124	29283147	X	-	27260156	PATU8902	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.7221464421549684	[307]	[487,582,715,1082]	7	hSpCas9	negative selection	8095465
29396378	29396401	X	+	27260156	PATU8902	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.8396076784432314	[188]	[537,401,391,580]	8	hSpCas9	negative selection	8095466
28789411	28789434	X	-	27260156	PATU8902	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.6394767139191794	[431]	[904,634,874,1396]	6	hSpCas9	negative selection	8095467
29282935	29282958	X	+	27260156	PATU8902	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.09193810670614688	[824]	[1544,1155,1244,892]	0	hSpCas9	negative selection	8159723
29396279	29396302	X	+	27260156	PATU8902	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.20106703751241306	[1101]	[2376,1587,1125,2155]	2	hSpCas9	negative selection	8159724
28789359	28789382	X	-	27260156	PATU8902	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.07675517321864256	[359]	[848,230,547,464]	0	hSpCas9	negative selection	8159725
29283124	29283147	X	-	27260156	PANC1	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.8246875777253316	[307]	[512,525,551,312]	9	hSpCas9	negative selection	8216716
29396378	29396401	X	+	27260156	PANC1	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.45021301387677626	[188]	[253,178,285,164]	7	hSpCas9	negative selection	8216717
28789411	28789434	X	-	27260156	PANC1	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.43397595750711476	[431]	[382,793,423,463]	7	hSpCas9	negative selection	8216718
29282935	29282958	X	+	27260156	PANC1	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.06793239610370805	[824]	[647,905,785,440]	-1	hSpCas9	negative selection	8280974
29396279	29396302	X	+	27260156	PANC1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.1564553298899649	[1101]	[983,1218,1192,872]	2	hSpCas9	negative selection	8280975
28789359	28789382	X	-	27260156	PANC1	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.11950141680832826	[359]	[250,299,283,299]	-2	hSpCas9	negative selection	8280976
29283124	29283147	X	-	27260156	PANC0813	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.27552738317446435	[307]	[495,358,574,332]	4	hSpCas9	negative selection	8337967
29396378	29396401	X	+	27260156	PANC0813	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.5892376161164969	[188]	[346,481,313,200]	8	hSpCas9	negative selection	8337968
28789411	28789434	X	-	27260156	PANC0813	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.8211071745835534	[431]	[666,1064,994,839]	9	hSpCas9	negative selection	8337969
29282935	29282958	X	+	27260156	PANC0813	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	0.04068213625765971	[824]	[990,839,1108,1042]	0	hSpCas9	negative selection	8402225
29396279	29396302	X	+	27260156	PANC0813	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.10583302695791152	[1101]	[1404,1363,1017,1048]	-2	hSpCas9	negative selection	8402226
28789359	28789382	X	-	27260156	PANC0813	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.10124173909729894	[359]	[367,570,489,380]	1	hSpCas9	negative selection	8402227
29283124	29283147	X	-	27260156	RDES	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.6439667608462873	[307]	[453,501,697,578]	9	hSpCas9	negative selection	8459218
29396378	29396401	X	+	27260156	RDES	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.5217193009285545	[188]	[248,272,350,397]	8	hSpCas9	negative selection	8459219
28789411	28789434	X	-	27260156	RDES	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.6365098295454849	[431]	[726,723,771,869]	8	hSpCas9	negative selection	8459220
29282935	29282958	X	+	27260156	RDES	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.004612955506945293	[824]	[837,881,945,1146]	0	hSpCas9	negative selection	8523476
29396279	29396302	X	+	27260156	RDES	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.0036019296423877023	[1101]	[1222,1035,1414,1397]	0	hSpCas9	negative selection	8523477
28789359	28789382	X	-	27260156	RDES	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.3495768440662703	[359]	[441,446,558,699]	5	hSpCas9	negative selection	8523478
29283124	29283147	X	-	27260156	PC3	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.34440941771360745	[307]	[196,369,644,505]	7	hSpCas9	negative selection	8580469
29396378	29396401	X	+	27260156	PC3	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.24078900313273666	[188]	[181,175,450,160]	5	hSpCas9	negative selection	8580470
28789411	28789434	X	-	27260156	PC3	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.36059458934821753	[431]	[418,473,1118,413]	7	hSpCas9	negative selection	8580471
29282935	29282958	X	+	27260156	PC3	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.1912752981079069	[824]	[542,657,1040,763]	-4	hSpCas9	negative selection	8644727
29396279	29396302	X	+	27260156	PC3	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.0019368777532915438	[1101]	[786,1219,1462,1064]	0	hSpCas9	negative selection	8644728
28789359	28789382	X	-	27260156	PC3	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.38561162087145073	[359]	[197,298,490,192]	-7	hSpCas9	negative selection	8644729
29283124	29283147	X	-	27260156	PATU8988T	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.24928646249731012	[307]	[418,228,367,389]	4	hSpCas9	negative selection	8701720
29396378	29396401	X	+	27260156	PATU8988T	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.17431461524466108	[188]	[239,205,228,143]	3	hSpCas9	negative selection	8701721
28789411	28789434	X	-	27260156	PATU8988T	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.4421177871143844	[431]	[612,410,597,636]	7	hSpCas9	negative selection	8701722
29282935	29282958	X	+	27260156	PATU8988T	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.23501424328471854	[824]	[849,601,805,421]	-4	hSpCas9	negative selection	8765978
29396279	29396302	X	+	27260156	PATU8988T	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.09876546957398702	[1101]	[936,1116,839,1105]	-2	hSpCas9	negative selection	8765979
28789359	28789382	X	-	27260156	PATU8988T	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.644154605789476	[359]	[187,215,175,317]	-7	hSpCas9	negative selection	8765980
29283124	29283147	X	-	27260156	T47D	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.5235625891025106	[307]	[436,522,563,537]	9	hSpCas9	negative selection	8822971
29396378	29396401	X	+	27260156	T47D	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.3485784183318027	[188]	[294,239,277,312]	7	hSpCas9	negative selection	8822972
28789411	28789434	X	-	27260156	T47D	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.31058534196805176	[431]	[548,600,693,653]	6	hSpCas9	negative selection	8822973
29282935	29282958	X	+	27260156	T47D	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.22963228134650726	[824]	[778,686,980,840]	-5	hSpCas9	negative selection	8887229
29396279	29396302	X	+	27260156	T47D	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.0812552754885505	[1101]	[1350,921,1284,1323]	-2	hSpCas9	negative selection	8887230
28789359	28789382	X	-	27260156	T47D	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.053939917157743045	[359]	[463,388,403,358]	-1	hSpCas9	negative selection	8887231
29283124	29283147	X	-	27260156	SU8686	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.5949333608339497	[307]	[389,395,405,703]	8	hSpCas9	negative selection	8944222
29396378	29396401	X	+	27260156	SU8686	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.2212072271279366	[188]	[151,197,223,325]	4	hSpCas9	negative selection	8944223
28789411	28789434	X	-	27260156	SU8686	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.5938931102988951	[431]	[673,602,689,611]	8	hSpCas9	negative selection	8944224
29282935	29282958	X	+	27260156	SU8686	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.13217392089409963	[824]	[564,630,913,941]	-2	hSpCas9	negative selection	9008480
29396279	29396302	X	+	27260156	SU8686	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.04318033178573555	[1101]	[1087,813,1159,1546]	0	hSpCas9	negative selection	9008481
28789359	28789382	X	-	27260156	SU8686	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.02223132258979088	[359]	[316,241,528,388]	0	hSpCas9	negative selection	9008482
29283124	29283147	X	-	27260156	SKES1	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.32866405840375135	[307]	[498,471,317,288]	7	hSpCas9	negative selection	9065473
29396378	29396401	X	+	27260156	SKES1	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.006220965110163235	[188]	[156,266,159,177]	0	hSpCas9	negative selection	9065474
28789411	28789434	X	-	27260156	SKES1	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.6455776758120406	[431]	[942,615,580,590]	9	hSpCas9	negative selection	9065475
29282935	29282958	X	+	27260156	SKES1	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.3815950044205173	[824]	[657,687,641,551]	-7	hSpCas9	negative selection	9129731
29396279	29396302	X	+	27260156	SKES1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.168016806578152	[1101]	[1008,1206,824,904]	-4	hSpCas9	negative selection	9129732
28789359	28789382	X	-	27260156	SKES1	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.14752348325163833	[359]	[326,349,355,269]	-3	hSpCas9	negative selection	9129733
29283124	29283147	X	-	27260156	TOV112D	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.5607790387647104	[307]	[410,470,461,474]	8	hSpCas9	negative selection	9186724
29396378	29396401	X	+	27260156	TOV112D	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.5196479176299369	[188]	[130,643,193,197]	8	hSpCas9	negative selection	9186725
28789411	28789434	X	-	27260156	TOV112D	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.7911618008253908	[431]	[622,1522,546,487]	9	hSpCas9	negative selection	9186726
29282935	29282958	X	+	27260156	TOV112D	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.4903742953152185	[824]	[754,595,438,577]	-7	hSpCas9	negative selection	9250982
29396279	29396302	X	+	27260156	TOV112D	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.1169298149619622	[1101]	[1141,1506,703,851]	-2	hSpCas9	negative selection	9250983
28789359	28789382	X	-	27260156	TOV112D	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	-0.1780767734581391	[359]	[314,386,315,273]	-3	hSpCas9	negative selection	9250984
29283124	29283147	X	-	27260156	TC71	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.40345646087138864	[307]	[455,405,396,491]	8	hSpCas9	negative selection	9307975
29396378	29396401	X	+	27260156	TC71	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	0.2589227984544329	[188]	[308,249,184,224]	6	hSpCas9	negative selection	9307976
28789411	28789434	X	-	27260156	TC71	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.4513735566997087	[431]	[661,520,607,748]	9	hSpCas9	negative selection	9307977
29282935	29282958	X	+	27260156	TC71	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.21908874634935893	[824]	[858,722,674,783]	-5	hSpCas9	negative selection	9372233
29396279	29396302	X	+	27260156	TC71	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.018189468647679563	[1101]	[1197,1001,1034,1451]	0	hSpCas9	negative selection	9372234
28789359	28789382	X	-	27260156	TC71	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.011424028139484232	[359]	[331,399,380,447]	0	hSpCas9	negative selection	9372235
29283124	29283147	X	-	27260156	TC32	viability	GCTCATTCTACTTCCGTCAAAGG	IL1RAPL1	ENSG00000169306	0.6145071308080537	[307]	[351,359,709,411]	8	hSpCas9	negative selection	9429226
29396378	29396401	X	+	27260156	TC32	viability	AATTTCATGCCGTGACATAGAGG	IL1RAPL1	ENSG00000169306	-0.16240289485022674	[188]	[126,156,222,131]	-3	hSpCas9	negative selection	9429227
28789411	28789434	X	-	27260156	TC32	viability	CTGCTTACCGGAGCCTCTTTTGG	IL1RAPL1	ENSG00000169306	0.6322365997730487	[431]	[531,614,697,662]	9	hSpCas9	negative selection	9429228
29282935	29282958	X	+	27260156	TC32	viability	TAGCCGATGGATGCACTGACTGG	IL1RAPL1	ENSG00000169306	-0.1477976740898196	[824]	[506,567,931,875]	-3	hSpCas9	negative selection	9493484
29396279	29396302	X	+	27260156	TC32	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.06609093413309974	[1101]	[858,770,1275,1149]	-1	hSpCas9	negative selection	9493485
28789359	28789382	X	-	27260156	TC32	viability	GCGTATAAGAGAATCAAGTGTGG	IL1RAPL1	ENSG00000169306	0.05261636384445567	[359]	[408,170,405,474]	1	hSpCas9	negative selection	9493486
29283160	29283183	X	-	27869803	HPAFII	viability after 27 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.2777301394737934	[184]	[165,293,NaN]	9	hSpCas9	negative selection	9608575
29396279	29396302	X	+	27869803	HPAFII	viability after 27 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.12022553231809946	[195]	[171,61,NaN]	0	hSpCas9	negative selection	9608579
29668431	29668454	X	-	27869803	HPAFII	viability after 27 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.6129203599523805	[179]	[129,156,NaN]	5	hSpCas9	negative selection	9608583
29917487	29917510	X	+	27869803	HPAFII	viability after 27 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.5579034884967352	[258]	[242,164,NaN]	4	hSpCas9	negative selection	9608584
29920071	29920094	X	-	27869803	HPAFII	viability after 27 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.3719989770268738	[284]	[38,322,NaN]	3	hSpCas9	negative selection	9608585
29941682	29941705	X	-	27869803	HPAFII	viability after 27 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.42866306750270367	[587]	[456,381,NaN]	3	hSpCas9	negative selection	9608587
29283160	29283183	X	-	27869803	HPAFII	viability after 15 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.0559192132837578	[184]	[577,310,NaN]	9	hSpCas9	negative selection	9691024
29396279	29396302	X	+	27869803	HPAFII	viability after 15 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.10725787829308647	[195]	[274,196,NaN]	1	hSpCas9	negative selection	9691028
29668431	29668454	X	-	27869803	HPAFII	viability after 15 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	1.0802916785033616	[179]	[540,326,NaN]	9	hSpCas9	negative selection	9691032
29917487	29917510	X	+	27869803	HPAFII	viability after 15 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.8793667722647968	[258]	[717,383,NaN]	8	hSpCas9	negative selection	9691033
29920071	29920094	X	-	27869803	HPAFII	viability after 15 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	-0.00012232466059661218	[284]	[362,270,NaN]	0	hSpCas9	negative selection	9691034
29941682	29941705	X	-	27869803	HPAFII	viability after 15 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.03797630908810423	[587]	[789,560,NaN]	0	hSpCas9	negative selection	9691036
29283160	29283183	X	-	27869803	ASPC1	viability after 36 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	0.7257790467743059	[563]	[475,401,155]	7	hSpCas9	negative selection	9773473
29396279	29396302	X	+	27869803	ASPC1	viability after 36 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.5450237291105815	[583]	[446,176,284]	5	hSpCas9	negative selection	9773477
29668431	29668454	X	-	27869803	ASPC1	viability after 36 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	-0.191316900672727	[330]	[195,72,55]	-2	hSpCas9	negative selection	9773481
29917487	29917510	X	+	27869803	ASPC1	viability after 36 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.46849443106363886	[837]	[462,397,364]	5	hSpCas9	negative selection	9773482
29920071	29920094	X	-	27869803	ASPC1	viability after 36 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.23344089317046662	[597]	[209,147,344]	2	hSpCas9	negative selection	9773483
29941682	29941705	X	-	27869803	ASPC1	viability after 36 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.05904961801692865	[1056]	[418,551,222]	0	hSpCas9	negative selection	9773485
29283160	29283183	X	-	27869803	PATU8988S	viability after 35 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.03607519306768281	[550]	[187,244,NaN]	0	hSpCas9	negative selection	9855922
29396279	29396302	X	+	27869803	PATU8988S	viability after 35 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.13938584718753652	[561]	[163,334,NaN]	1	hSpCas9	negative selection	9855926
29668431	29668454	X	-	27869803	PATU8988S	viability after 35 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.5069409041514137	[316]	[148,213,NaN]	5	hSpCas9	negative selection	9855930
29917487	29917510	X	+	27869803	PATU8988S	viability after 35 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.3711266006753141	[644]	[327,343,NaN]	4	hSpCas9	negative selection	9855931
29920071	29920094	X	-	27869803	PATU8988S	viability after 35 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.9212941563268631	[393]	[307,292,NaN]	8	hSpCas9	negative selection	9855932
29941682	29941705	X	-	27869803	PATU8988S	viability after 35 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.8873722275383409	[1018]	[611,906,NaN]	8	hSpCas9	negative selection	9855934
29283160	29283183	X	-	27869803	PATU8988S	viability after 31 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	-0.3472355928443458	[550]	[122,235,NaN]	-4	hSpCas9	negative selection	9938371
29396279	29396302	X	+	27869803	PATU8988S	viability after 31 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.24181534895189877	[561]	[198,348,NaN]	3	hSpCas9	negative selection	9938375
29668431	29668454	X	-	27869803	PATU8988S	viability after 31 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.6853161551473635	[316]	[109,321,NaN]	7	hSpCas9	negative selection	9938379
29917487	29917510	X	+	27869803	PATU8988S	viability after 31 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.49750703075237146	[644]	[425,282,NaN]	6	hSpCas9	negative selection	9938380
29920071	29920094	X	-	27869803	PATU8988S	viability after 31 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.987214887192629	[393]	[299,325,NaN]	9	hSpCas9	negative selection	9938381
29941682	29941705	X	-	27869803	PATU8988S	viability after 31 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.8241273629592514	[1018]	[593,878,NaN]	8	hSpCas9	negative selection	9938383
29283160	29283183	X	-	27869803	HPAFII	viability after 35 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.5202391157810198	[184]	[135,417,NaN]	8	hSpCas9	negative selection	10020820
29396279	29396302	X	+	27869803	HPAFII	viability after 35 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.017550664675032634	[195]	[154,38,NaN]	0	hSpCas9	negative selection	10020824
29668431	29668454	X	-	27869803	HPAFII	viability after 35 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.869048615096013	[179]	[93,247,NaN]	6	hSpCas9	negative selection	10020828
29917487	29917510	X	+	27869803	HPAFII	viability after 35 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.29183409742749883	[258]	[128,195,NaN]	1	hSpCas9	negative selection	10020829
29920071	29920094	X	-	27869803	HPAFII	viability after 35 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.35343330175410914	[284]	[22,365,NaN]	2	hSpCas9	negative selection	10020830
29941682	29941705	X	-	27869803	HPAFII	viability after 35 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.11267949500634034	[587]	[303,242,NaN]	0	hSpCas9	negative selection	10020832
29283160	29283183	X	-	27869803	HPAFII	viability after 31 days	CAATGTTGGCCGGAACCAAATGG	IL1RAPL1	ENSG00000169306	1.3473983845934239	[184]	[178,356,NaN]	8	hSpCas9	negative selection	10103269
29396279	29396302	X	+	27869803	HPAFII	viability after 31 days	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.0830243986316796	[195]	[194,30,NaN]	0	hSpCas9	negative selection	10103273
29668431	29668454	X	-	27869803	HPAFII	viability after 31 days	TGGGTGGCTTATCAGTCAGAGGG	IL1RAPL1	ENSG00000169306	0.8463087219050693	[179]	[94,275,NaN]	6	hSpCas9	negative selection	10103277
29917487	29917510	X	+	27869803	HPAFII	viability after 31 days	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.5683460455734836	[258]	[193,238,NaN]	4	hSpCas9	negative selection	10103278
29920071	29920094	X	-	27869803	HPAFII	viability after 31 days	TCGTTTATGAAGGAGAACGCTGG	IL1RAPL1	ENSG00000169306	0.28841778366464066	[284]	[68,332,NaN]	2	hSpCas9	negative selection	10103279
29941682	29941705	X	-	27869803	HPAFII	viability after 31 days	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.3482997257393766	[587]	[196,326,NaN]	-2	hSpCas9	negative selection	10103281
29941773	29941796	X	+	28162770	P31FUJ	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.36137882633615637	[207]	[313]	4	hSpCas9	negative selection	10174092
29954571	29954594	X	+	28162770	P31FUJ	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.30163273769899357	[1045]	[1514]	3	hSpCas9	negative selection	10174093
29954555	29954578	X	+	28162770	P31FUJ	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.7287236477709856	[341]	[665]	8	hSpCas9	negative selection	10174094
29283049	29283072	X	-	28162770	P31FUJ	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.8417447489506751	[65]	[138]	8	hSpCas9	negative selection	10174095
29396295	29396318	X	+	28162770	P31FUJ	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.6237727921213649	[353]	[640]	7	hSpCas9	negative selection	10174096
29668430	29668453	X	-	28162770	P31FUJ	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.4143885964821185	[241]	[378]	4	hSpCas9	negative selection	10174097
29941659	29941682	X	+	28162770	P31FUJ	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	1.0727003425598727	[52]	[130]	9	hSpCas9	negative selection	10174098
29941682	29941705	X	-	28162770	P31FUJ	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.8345530633873859	[407]	[854]	8	hSpCas9	negative selection	10174099
29396279	29396302	X	+	28162770	P31FUJ	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	10174100
29917487	29917510	X	+	28162770	P31FUJ	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.584033770654111	[519]	[915]	6	hSpCas9	negative selection	10174101
29941773	29941796	X	+	28162770	TF1	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[170]	1	hSpCas9	negative selection	10343458
29954571	29954594	X	+	28162770	TF1	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[772]	1	hSpCas9	negative selection	10343459
29954555	29954578	X	+	28162770	TF1	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[392]	1	hSpCas9	negative selection	10343460
29283049	29283072	X	-	28162770	TF1	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[121]	1	hSpCas9	negative selection	10343461
29396295	29396318	X	+	28162770	TF1	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[304]	1	hSpCas9	negative selection	10343462
29668430	29668453	X	-	28162770	TF1	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10343463
29941659	29941682	X	+	28162770	TF1	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10343464
29941682	29941705	X	-	28162770	TF1	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[322]	1	hSpCas9	negative selection	10343465
29396279	29396302	X	+	28162770	TF1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10343466
29917487	29917510	X	+	28162770	TF1	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	NaN	[NaN]	[784]	1	hSpCas9	negative selection	10343467
29941773	29941796	X	+	28162770	SKM1	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.2672656400750819	[46]	[99]	2	hSpCas9	negative selection	10512824
29954571	29954594	X	+	28162770	SKM1	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.6208700094535642	[230]	[627]	6	hSpCas9	negative selection	10512825
29954555	29954578	X	+	28162770	SKM1	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.4332553572200689	[92]	[221]	4	hSpCas9	negative selection	10512826
29283049	29283072	X	-	28162770	SKM1	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.8278119470491185	[28]	[90]	7	hSpCas9	negative selection	10512827
29396295	29396318	X	+	28162770	SKM1	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	-0.14554084281535307	[111]	[178]	-1	hSpCas9	negative selection	10512828
29668430	29668453	X	-	28162770	SKM1	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.7060984657434741	[68]	[198]	6	hSpCas9	negative selection	10512829
29941659	29941682	X	+	28162770	SKM1	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	0.73439165050238	[16]	[49]	7	hSpCas9	negative selection	10512830
29941682	29941705	X	-	28162770	SKM1	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.031156913648723306	[92]	[167]	0	hSpCas9	negative selection	10512831
29396279	29396302	X	+	28162770	SKM1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10512832
29917487	29917510	X	+	28162770	SKM1	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.6576078025529222	[141]	[395]	6	hSpCas9	negative selection	10512833
29941773	29941796	X	+	28162770	SKM1	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.2672656400750819	[46]	[99]	2	hSpCas9	negative selection	10682190
29954571	29954594	X	+	28162770	SKM1	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.6208700094535642	[230]	[627]	6	hSpCas9	negative selection	10682191
29954555	29954578	X	+	28162770	SKM1	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.4332553572200689	[92]	[221]	4	hSpCas9	negative selection	10682192
29283049	29283072	X	-	28162770	SKM1	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.8278119470491185	[28]	[90]	7	hSpCas9	negative selection	10682193
29396295	29396318	X	+	28162770	SKM1	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	-0.14554084281535307	[111]	[178]	-1	hSpCas9	negative selection	10682194
29668430	29668453	X	-	28162770	SKM1	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.7060984657434741	[68]	[198]	6	hSpCas9	negative selection	10682195
29941659	29941682	X	+	28162770	SKM1	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	0.73439165050238	[16]	[49]	7	hSpCas9	negative selection	10682196
29941682	29941705	X	-	28162770	SKM1	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.031156913648723306	[92]	[167]	0	hSpCas9	negative selection	10682197
29396279	29396302	X	+	28162770	SKM1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10682198
29917487	29917510	X	+	28162770	SKM1	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.6576078025529222	[141]	[395]	6	hSpCas9	negative selection	10682199
29941773	29941796	X	+	28162770	PL21	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.2894069525864074	[187]	[99]	2	hSpCas9	negative selection	10851556
29954571	29954594	X	+	28162770	PL21	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.6323778545217722	[666]	[449]	5	hSpCas9	negative selection	10851557
29954555	29954578	X	+	28162770	PL21	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.44888336277272034	[371]	[220]	4	hSpCas9	negative selection	10851558
29283049	29283072	X	-	28162770	PL21	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.13364420270241317	[110]	[52]	1	hSpCas9	negative selection	10851559
29396295	29396318	X	+	28162770	PL21	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.4532096341047709	[338]	[201]	4	hSpCas9	negative selection	10851560
29668430	29668453	X	-	28162770	PL21	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.02214131251132581	[223]	[98]	0	hSpCas9	negative selection	10851561
29941659	29941682	X	+	28162770	PL21	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	0.0723840672909477	[58]	[26]	0	hSpCas9	negative selection	10851562
29941682	29941705	X	-	28162770	PL21	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.32985343670525946	[286]	[156]	3	hSpCas9	negative selection	10851563
29396279	29396302	X	+	28162770	PL21	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10851564
29917487	29917510	X	+	28162770	PL21	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.6815890290107358	[466]	[325]	6	hSpCas9	negative selection	10851565
29941773	29941796	X	+	28162770	P31FUJ	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.36137882633615637	[207]	[313]	4	hSpCas9	negative selection	11020922
29954571	29954594	X	+	28162770	P31FUJ	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.30163273769899357	[1045]	[1514]	3	hSpCas9	negative selection	11020923
29954555	29954578	X	+	28162770	P31FUJ	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.7287236477709856	[341]	[665]	8	hSpCas9	negative selection	11020924
29283049	29283072	X	-	28162770	P31FUJ	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.8417447489506751	[65]	[138]	8	hSpCas9	negative selection	11020925
29396295	29396318	X	+	28162770	P31FUJ	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.6237727921213649	[353]	[640]	7	hSpCas9	negative selection	11020926
29668430	29668453	X	-	28162770	P31FUJ	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.4143885964821185	[241]	[378]	4	hSpCas9	negative selection	11020927
29941659	29941682	X	+	28162770	P31FUJ	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	1.0727003425598727	[52]	[130]	9	hSpCas9	negative selection	11020928
29941682	29941705	X	-	28162770	P31FUJ	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.8345530633873859	[407]	[854]	8	hSpCas9	negative selection	11020929
29396279	29396302	X	+	28162770	P31FUJ	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.23280220441437827	[0]	[0]	-2	hSpCas9	negative selection	11020930
29917487	29917510	X	+	28162770	P31FUJ	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.584033770654111	[519]	[915]	6	hSpCas9	negative selection	11020931
29941773	29941796	X	+	28162770	OCIAML5	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.2838168572177761	[161]	[355]	2	hSpCas9	negative selection	11190288
29954571	29954594	X	+	28162770	OCIAML5	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.4659304724334503	[587]	[1465]	4	hSpCas9	negative selection	11190289
29954555	29954578	X	+	28162770	OCIAML5	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.7892467842385228	[158]	[495]	7	hSpCas9	negative selection	11190290
29283049	29283072	X	-	28162770	OCIAML5	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.975353974247713	[50]	[180]	8	hSpCas9	negative selection	11190291
29396295	29396318	X	+	28162770	OCIAML5	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.0175878273099066	[190]	[348]	0	hSpCas9	negative selection	11190292
29668430	29668453	X	-	28162770	OCIAML5	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.5334841639144661	[172]	[451]	4	hSpCas9	negative selection	11190293
29941659	29941682	X	+	28162770	OCIAML5	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	0.7328959298571593	[32]	[98]	6	hSpCas9	negative selection	11190294
29941682	29941705	X	-	28162770	OCIAML5	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.644871182059935	[213]	[603]	5	hSpCas9	negative selection	11190295
29396279	29396302	X	+	28162770	OCIAML5	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.8520665708639967	[0]	[0]	-5	hSpCas9	negative selection	11190296
29917487	29917510	X	+	28162770	OCIAML5	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.8894960374123064	[281]	[942]	7	hSpCas9	negative selection	11190297
29941773	29941796	X	+	28162770	EOL1	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.9023178241870691	[326]	[321]	7	hSpCas9	negative selection	11359654
29954571	29954594	X	+	28162770	EOL1	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.7334448584365445	[934]	[818]	6	hSpCas9	negative selection	11359655
29954555	29954578	X	+	28162770	EOL1	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	1.76072296966464	[530]	[947]	9	hSpCas9	negative selection	11359656
29283049	29283072	X	-	28162770	EOL1	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	-0.3936281884557201	[191]	[76]	-3	hSpCas9	negative selection	11359657
29396295	29396318	X	+	28162770	EOL1	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.09672874695321498	[567]	[319]	0	hSpCas9	negative selection	11359658
29668430	29668453	X	-	28162770	EOL1	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	1.0114459940513338	[450]	[478]	8	hSpCas9	negative selection	11359659
29941659	29941682	X	+	28162770	EOL1	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	-0.9499213463456062	[65]	[17]	-6	hSpCas9	negative selection	11359660
29941682	29941705	X	-	28162770	EOL1	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.5553139619048157	[309]	[239]	5	hSpCas9	negative selection	11359661
29396279	29396302	X	+	28162770	EOL1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.07545222842946586	[1]	[0]	0	hSpCas9	negative selection	11359662
29917487	29917510	X	+	28162770	EOL1	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.8250120980196203	[629]	[587]	7	hSpCas9	negative selection	11359663
29941773	29941796	X	+	28162770	MOLM13	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.9172783856141997	[248]	[339]	7	hSpCas9	negative selection	11529020
29954571	29954594	X	+	28162770	MOLM13	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.9094140469639596	[876]	[1190]	7	hSpCas9	negative selection	11529021
29954555	29954578	X	+	28162770	MOLM13	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	1.1904587546342813	[422]	[697]	8	hSpCas9	negative selection	11529022
29283049	29283072	X	-	28162770	MOLM13	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.837123191210298	[167]	[216]	6	hSpCas9	negative selection	11529023
29396295	29396318	X	+	28162770	MOLM13	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	1.4039669901757514	[472]	[904]	9	hSpCas9	negative selection	11529024
29668430	29668453	X	-	28162770	MOLM13	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.6050082379036498	[340]	[374]	4	hSpCas9	negative selection	11529025
29941659	29941682	X	+	28162770	MOLM13	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	-1.055672574512434	[91]	[31]	-5	hSpCas9	negative selection	11529026
29941682	29941705	X	-	28162770	MOLM13	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.023451485047462417	[439]	[312]	0	hSpCas9	negative selection	11529027
29396279	29396302	X	+	28162770	MOLM13	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.4678893815445777	[0]	[0]	3	hSpCas9	negative selection	11529028
29917487	29917510	X	+	28162770	MOLM13	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	1.1207729545663832	[649]	[1021]	8	hSpCas9	negative selection	11529029
29941773	29941796	X	+	28162770	HEL	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.8537264900645554	[253]	[293]	7	hSpCas9	negative selection	11698386
29954571	29954594	X	+	28162770	HEL	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	1.0667094560492085	[804]	[1079]	8	hSpCas9	negative selection	11698387
29954555	29954578	X	+	28162770	HEL	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.8770142448527267	[379]	[446]	7	hSpCas9	negative selection	11698388
29283049	29283072	X	-	28162770	HEL	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	1.5075792487187212	[122]	[223]	9	hSpCas9	negative selection	11698389
29396295	29396318	X	+	28162770	HEL	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.9026059587554676	[379]	[454]	7	hSpCas9	negative selection	11698390
29668430	29668453	X	-	28162770	HEL	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	1.3078716814054965	[279]	[443]	9	hSpCas9	negative selection	11698391
29941659	29941682	X	+	28162770	HEL	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	0.4968879655369023	[51]	[46]	4	hSpCas9	negative selection	11698392
29941682	29941705	X	-	28162770	HEL	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.44531734466483913	[303]	[142]	-3	hSpCas9	negative selection	11698393
29396279	29396302	X	+	28162770	HEL	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	2.642738832000357	[0]	[3]	9	hSpCas9	negative selection	11698394
29917487	29917510	X	+	28162770	HEL	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.3756773613301809	[573]	[476]	3	hSpCas9	negative selection	11698395
29941773	29941796	X	+	28162770	MV411	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.9673296315900402	[186]	[307]	8	hSpCas9	negative selection	11867752
29954571	29954594	X	+	28162770	MV411	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.4124967970532716	[692]	[776]	3	hSpCas9	negative selection	11867753
29954555	29954578	X	+	28162770	MV411	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	1.0592985515922906	[273]	[480]	8	hSpCas9	negative selection	11867754
29283049	29283072	X	-	28162770	MV411	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.16497539059080213	[89]	[84]	1	hSpCas9	negative selection	11867755
29396295	29396318	X	+	28162770	MV411	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	1.0541462488470934	[318]	[557]	8	hSpCas9	negative selection	11867756
29668430	29668453	X	-	28162770	MV411	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	1.0395446991414425	[230]	[399]	8	hSpCas9	negative selection	11867757
29941659	29941682	X	+	28162770	MV411	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	-0.35663377288608533	[37]	[24]	-3	hSpCas9	negative selection	11867758
29941682	29941705	X	-	28162770	MV411	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	-0.1709667995944672	[285]	[213]	-1	hSpCas9	negative selection	11867759
29396279	29396302	X	+	28162770	MV411	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11867760
29917487	29917510	X	+	28162770	MV411	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	-0.22972166040386588	[521]	[374]	-2	hSpCas9	negative selection	11867761
29941773	29941796	X	+	28162770	MONOMAC1	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.4487808590484571	[146]	[229]	4	hSpCas9	negative selection	12037118
29954571	29954594	X	+	28162770	MONOMAC1	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.3327570627089742	[461]	[666]	3	hSpCas9	negative selection	12037119
29954555	29954578	X	+	28162770	MONOMAC1	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	-0.21488484839247834	[243]	[240]	-2	hSpCas9	negative selection	12037120
29283049	29283072	X	-	28162770	MONOMAC1	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	-0.17278930081287647	[58]	[59]	-1	hSpCas9	negative selection	12037121
29396295	29396318	X	+	28162770	MONOMAC1	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.4455363768316978	[179]	[280]	4	hSpCas9	negative selection	12037122
29668430	29668453	X	-	28162770	MONOMAC1	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.2180006522192901	[167]	[223]	2	hSpCas9	negative selection	12037123
29941659	29941682	X	+	28162770	MONOMAC1	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	-0.602293325545812	[48]	[36]	-5	hSpCas9	negative selection	12037124
29941682	29941705	X	-	28162770	MONOMAC1	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.10929439277678998	[185]	[229]	1	hSpCas9	negative selection	12037125
29396279	29396302	X	+	28162770	MONOMAC1	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	12037126
29917487	29917510	X	+	28162770	MONOMAC1	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.2613616923779327	[253]	[348]	2	hSpCas9	negative selection	12037127
29941773	29941796	X	+	28162770	OCIAML2	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.6575958849197628	[38]	[340]	6	hSpCas9	negative selection	12206484
29954571	29954594	X	+	28162770	OCIAML2	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.8144506866188903	[114]	[1120]	7	hSpCas9	negative selection	12206485
29954555	29954578	X	+	28162770	OCIAML2	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	0.6803120728325782	[67]	[603]	6	hSpCas9	negative selection	12206486
29283049	29283072	X	-	28162770	OCIAML2	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	0.4815416496672236	[22]	[177]	5	hSpCas9	negative selection	12206487
29396295	29396318	X	+	28162770	OCIAML2	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	1.1273888283044413	[54]	[665]	9	hSpCas9	negative selection	12206488
29668430	29668453	X	-	28162770	OCIAML2	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.9920769254279971	[39]	[440]	8	hSpCas9	negative selection	12206489
29941659	29941682	X	+	28162770	OCIAML2	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	1.392868174852977	[8]	[130]	9	hSpCas9	negative selection	12206490
29941682	29941705	X	-	28162770	OCIAML2	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.6551557474665781	[58]	[514]	6	hSpCas9	negative selection	12206491
29396279	29396302	X	+	28162770	OCIAML2	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12206492
29917487	29917510	X	+	28162770	OCIAML2	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.48872819026049275	[80]	[629]	5	hSpCas9	negative selection	12206493
29941773	29941796	X	+	28162770	OCIAML3	viability	GGAGCTGAAGAGCTCGATGGAGG	IL1RAPL1	ENSG00000169306	0.7835940522523579	[60]	[316]	7	hSpCas9	negative selection	12375850
29954571	29954594	X	+	28162770	OCIAML3	viability	CCAGTGGAATCAAGAGACTGGGG	IL1RAPL1	ENSG00000169306	0.6242091050410914	[172]	[804]	5	hSpCas9	negative selection	12375851
29954555	29954578	X	+	28162770	OCIAML3	viability	CCAAAGTGGATCCTGACCAGTGG	IL1RAPL1	ENSG00000169306	1.3370450059583456	[74]	[571]	9	hSpCas9	negative selection	12375852
29283049	29283072	X	-	28162770	OCIAML3	viability	GAGTCCAGCACTTTGGGCAAGGG	IL1RAPL1	ENSG00000169306	-0.022101292428453267	[36]	[109]	0	hSpCas9	negative selection	12375853
29396295	29396318	X	+	28162770	OCIAML3	viability	ACAGTGGGTGAAAATGACACTGG	IL1RAPL1	ENSG00000169306	0.9172829485162937	[76]	[438]	7	hSpCas9	negative selection	12375854
29668430	29668453	X	-	28162770	OCIAML3	viability	GGGTGGCTTATCAGTCAGAGGGG	IL1RAPL1	ENSG00000169306	0.18261415419383323	[60]	[208]	1	hSpCas9	negative selection	12375855
29941659	29941682	X	+	28162770	OCIAML3	viability	TACACAGTGGAACTTGCTGGAGG	IL1RAPL1	ENSG00000169306	-0.30712649253600177	[24]	[60]	-2	hSpCas9	negative selection	12375856
29941682	29941705	X	-	28162770	OCIAML3	viability	GCAGCAAGAGTATAGCACCAAGG	IL1RAPL1	ENSG00000169306	0.49552358126740526	[81]	[348]	4	hSpCas9	negative selection	12375857
29396279	29396302	X	+	28162770	OCIAML3	viability	AGTATCCATCTCACTGACAGTGG	IL1RAPL1	ENSG00000169306	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12375858
29917487	29917510	X	+	28162770	OCIAML3	viability	AGAGCTTTCTTTGGGTACAGCGG	IL1RAPL1	ENSG00000169306	0.14578399792080643	[152]	[510]	1	hSpCas9	negative selection	12375859