| 30752030 | 30752053 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CAAGGAAAGGCATACTTGGGAGG | INMT | ENSG00000241644 | 1.4506627442676023 | [24,28] | [16,14] | 5 | dCas9-VP64 | positive selection | 2410302 | 30752001 | 30752024 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCCTTCTAGGGGGATGCAGAAGG | INMT | ENSG00000241644 | -2.5717120091178494 | [85,26] | [0,1] | -9 | dCas9-VP64 | positive selection | 2410303 | 30751940 | 30751963 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | TCTGGGGTTGGGGAAACCTCAGG | INMT | ENSG00000241644 | 1.6185794565904517 | [168,113] | [156,28] | 6 | dCas9-VP64 | positive selection | 2410304 | 30700280 | 30700303 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | CCCCTTCTCTGCAGGCTGGATGG | INMT | ENSG00000241644 | -0.3200630642246347 | [57,373] | [30,45] | -1 | dCas9-VP64 | positive selection | 2411244 | 30700259 | 30700282 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGAGAGCATAGCCCCTTGGCTGG | INMT | ENSG00000241644 | 0.6091247750629185 | [13,48] | [1,18] | 2 | dCas9-VP64 | positive selection | 2411245 | 30700216 | 30700239 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGGACCAGCTATAAATAACCTGG | INMT | ENSG00000241644 | 0.6937830326372744 | [99,67] | [18,40] | 3 | dCas9-VP64 | positive selection | 2411246 | 30732369 | 30732392 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (puromycin) | GGAGTGCGGTGGCACAATCTCAG | INMT | ENSG00000241644 | 0.34388664028494687 | [9,101] | [1,29] | 1 | dCas9-VP64 | positive selection | 2425826 | 30752030 | 30752053 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CAAGGAAAGGCATACTTGGGAGG | INMT | ENSG00000241644 | -0.48888022568365735 | [185,208] | [33,55] | -5 | dCas9-VP64 | positive selection | 2505557 | 30752001 | 30752024 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCCTTCTAGGGGGATGCAGAAGG | INMT | ENSG00000241644 | -0.05644651874555828 | [65,20] | [8,16] | 0 | dCas9-VP64 | positive selection | 2505558 | 30751940 | 30751963 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | TCTGGGGTTGGGGAAACCTCAGG | INMT | ENSG00000241644 | 0.2871159562873408 | [102,126] | [18,69] | 2 | dCas9-VP64 | positive selection | 2505559 | 30700280 | 30700303 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | CCCCTTCTCTGCAGGCTGGATGG | INMT | ENSG00000241644 | -0.10627300911572557 | [158,202] | [77,31] | -1 | dCas9-VP64 | positive selection | 2506499 | 30700259 | 30700282 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGAGAGCATAGCCCCTTGGCTGG | INMT | ENSG00000241644 | -0.7094808416338036 | [22,157] | [13,19] | -6 | dCas9-VP64 | positive selection | 2506500 | 30700216 | 30700239 | 7 | - | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGGACCAGCTATAAATAACCTGG | INMT | ENSG00000241644 | 0.40302334183173416 | [46,31] | [25,7] | 3 | dCas9-VP64 | positive selection | 2506501 | 30732369 | 30732392 | 7 | + | 25494202 | A375 | resistance to PLX-4720 (zeocin) | GGAGTGCGGTGGCACAATCTCAG | INMT | ENSG00000241644 | -0.06548600402502203 | [51,72] | [16,20] | 0 | dCas9-VP64 | positive selection | 2521081 | 30699933 | 30699956 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.3831098718782717 | [2] | [1,0] | -7 | hSpCas9 | positive selection | 4129653 | 30699933 | 30699956 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.3355463407396587 | [1] | [0,2,0,0] | 2 | hSpCas9 | positive selection | 4193675 | 30699933 | 30699956 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.3754384505243788 | [3] | [2,3] | 7 | hSpCas9 | positive selection | 4264840 | 30699985 | 30700008 | 7 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.3628918518378901 | [0] | [0,0] | 7 | hSpCas9 | positive selection | 4329110 | 30699933 | 30699956 | 7 | + | 27260156 | BXPC3 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.19067610429511847 | [468] | [413,413,310,597] | -4 | hSpCas9 | negative selection | 5537300 | 30699985 | 30700008 | 7 | + | 27260156 | BXPC3 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.06171780769732926 | [0] | [0,0,0,0] | -1 | hSpCas9 | negative selection | 5601570 | 30699933 | 30699956 | 7 | + | 27260156 | A673 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.017165190373536858 | [468] | [666,569,488,563] | 0 | hSpCas9 | negative selection | 5658551 | 30699985 | 30700008 | 7 | + | 27260156 | A673 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.2631622979798074 | [0] | [0,0,0,0] | -6 | hSpCas9 | negative selection | 5722821 | 30699933 | 30699956 | 7 | + | 27260156 | A375 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.2853686664814651 | [468] | [495,588,263,464] | -4 | hSpCas9 | negative selection | 5779802 | 30699985 | 30700008 | 7 | + | 27260156 | A375 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.22260698094002684 | [0] | [0,0,0,0] | -3 | hSpCas9 | negative selection | 5844072 | 30699933 | 30699956 | 7 | + | 27260156 | COLO741 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.26522748052872774 | [468] | [674,428,411] | -5 | hSpCas9 | negative selection | 5901053 | 30699985 | 30700008 | 7 | + | 27260156 | COLO741 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.3524737808476335 | [0] | [0,0,0] | -6 | hSpCas9 | negative selection | 5965323 | 30699933 | 30699956 | 7 | + | 27260156 | CAL120 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.05123955412963822 | [468] | [630,632,437] | 0 | hSpCas9 | negative selection | 6022304 | 30699985 | 30700008 | 7 | + | 27260156 | CAL120 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.31522623407729533 | [0] | [0,0,0] | -4 | hSpCas9 | negative selection | 6086574 | 30699933 | 30699956 | 7 | + | 27260156 | CADOES1 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.39670157141784784 | [468] | [345,414,321,238] | -6 | hSpCas9 | negative selection | 6143555 | 30699985 | 30700008 | 7 | + | 27260156 | CADOES1 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.1046074123573355 | [0] | [0,0,0,0] | 1 | hSpCas9 | negative selection | 6207825 | 30699933 | 30699956 | 7 | + | 27260156 | EWS502 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.1335412442285717 | [468] | [461,596,534,594] | 2 | hSpCas9 | negative selection | 6264806 | 30699985 | 30700008 | 7 | + | 27260156 | EWS502 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.08156866895534698 | [0] | [0,0,0,0] | -1 | hSpCas9 | negative selection | 6329076 | 30699933 | 30699956 | 7 | + | 27260156 | EW8 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.055299074110845094 | [468] | [521,296,288,383] | -1 | hSpCas9 | negative selection | 6386057 | 30699985 | 30700008 | 7 | + | 27260156 | EW8 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.30430985650646214 | [0] | [0,0,0,0] | 5 | hSpCas9 | negative selection | 6450327 | 30699933 | 30699956 | 7 | + | 27260156 | CORL105 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.045665245221421936 | [468] | [488,514,711,438] | -1 | hSpCas9 | negative selection | 6507308 | 30699985 | 30700008 | 7 | + | 27260156 | CORL105 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.22721281181091513 | [0] | [0,0,0,0] | -4 | hSpCas9 | negative selection | 6571578 | 30699933 | 30699956 | 7 | + | 27260156 | HS294T | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.47510850737831545 | [468] | [182,289,301,234] | 6 | hSpCas9 | negative selection | 6628559 | 30699985 | 30700008 | 7 | + | 27260156 | HS294T | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 1.3721219085074186 | [0] | [0,0,0,0] | 9 | hSpCas9 | negative selection | 6692829 | 30699933 | 30699956 | 7 | + | 27260156 | HCC44 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.19989760590506897 | [468] | [769,318,682,724] | 3 | hSpCas9 | negative selection | 6749810 | 30699985 | 30700008 | 7 | + | 27260156 | HCC44 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.17453351620550883 | [0] | [0,0,0,0] | -3 | hSpCas9 | negative selection | 6814080 | 30699933 | 30699956 | 7 | + | 27260156 | G402 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.588606918870347 | [468] | [330,427,517,245] | -6 | hSpCas9 | negative selection | 6871061 | 30699985 | 30700008 | 7 | + | 27260156 | G402 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.28565990241013317 | [0] | [0,0,0,0] | -4 | hSpCas9 | negative selection | 6935331 | 30699933 | 30699956 | 7 | + | 27260156 | L33 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.2173251431361488 | [468] | [506,215,378,544] | 5 | hSpCas9 | negative selection | 6992312 | 30699985 | 30700008 | 7 | + | 27260156 | L33 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.5883332593072037 | [0] | [0,0,0,0] | 9 | hSpCas9 | negative selection | 7056582 | 30699933 | 30699956 | 7 | + | 27260156 | K562 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.6699055025083863 | [468] | [286,213,207,327] | -7 | hSpCas9 | negative selection | 7113563 | 30699985 | 30700008 | 7 | + | 27260156 | K562 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.1738498320762858 | [0] | [0,0,0,0] | 2 | hSpCas9 | negative selection | 7177833 | 30699933 | 30699956 | 7 | + | 27260156 | HT29 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.04929522053910724 | [468] | [619,467,585,663] | 0 | hSpCas9 | negative selection | 7234814 | 30699985 | 30700008 | 7 | + | 27260156 | HT29 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.27901894800515237 | [0] | [0,0,0,0] | -5 | hSpCas9 | negative selection | 7299084 | 30699933 | 30699956 | 7 | + | 27260156 | MHHES1 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.10231468183837561 | [468] | [684,536,485,317] | -2 | hSpCas9 | negative selection | 7356065 | 30699985 | 30700008 | 7 | + | 27260156 | MHHES1 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.1630968580950416 | [0] | [0,0,0,0] | -3 | hSpCas9 | negative selection | 7420335 | 30699933 | 30699956 | 7 | + | 27260156 | MEWO | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.06179963150203028 | [468] | [520,325,433] | -1 | hSpCas9 | negative selection | 7477316 | 30699985 | 30700008 | 7 | + | 27260156 | MEWO | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.09620936660807722 | [0] | [0,0,0] | 2 | hSpCas9 | negative selection | 7541586 | 30699933 | 30699956 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.2003590766569488 | [468] | [332,249,494,427] | -3 | hSpCas9 | negative selection | 7598567 | 30699985 | 30700008 | 7 | + | 27260156 | LNCAPCLONEFGC | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.14289828313858877 | [0] | [0,0,0,0] | 2 | hSpCas9 | negative selection | 7662837 | 30699933 | 30699956 | 7 | + | 27260156 | PANC0327 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.02568157803888694 | [468] | [356,385,574,317] | 0 | hSpCas9 | negative selection | 7719818 | 30699985 | 30700008 | 7 | + | 27260156 | PANC0327 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.17097580133514256 | [0] | [0,0,0,0] | 2 | hSpCas9 | negative selection | 7784088 | 30699933 | 30699956 | 7 | + | 27260156 | NCIH2009 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.16879938600305666 | [468] | [975,508,774] | 2 | hSpCas9 | negative selection | 7841069 | 30699985 | 30700008 | 7 | + | 27260156 | NCIH2009 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.4816251237464222 | [0] | [0,0,0] | -6 | hSpCas9 | negative selection | 7905339 | 30699933 | 30699956 | 7 | + | 27260156 | NCIH1373 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.2909109749890353 | [468] | [343,389,435,142] | -3 | hSpCas9 | negative selection | 7962320 | 30699985 | 30700008 | 7 | + | 27260156 | NCIH1373 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.5801096359471138 | [0] | [0,0,0,0] | 6 | hSpCas9 | negative selection | 8026590 | 30699933 | 30699956 | 7 | + | 27260156 | PATU8902 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.03432897685295412 | [468] | [561,646,316,1167] | 0 | hSpCas9 | negative selection | 8083571 | 30699985 | 30700008 | 7 | + | 27260156 | PATU8902 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.47507721586162077 | [0] | [0,0,0,0] | -5 | hSpCas9 | negative selection | 8147841 | 30699933 | 30699956 | 7 | + | 27260156 | PANC1 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.4438810006401078 | [468] | [191,366,342,294] | -6 | hSpCas9 | negative selection | 8204822 | 30699985 | 30700008 | 7 | + | 27260156 | PANC1 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.22557163962344795 | [0] | [0,0,0,0] | 3 | hSpCas9 | negative selection | 8269092 | 30699933 | 30699956 | 7 | + | 27260156 | PANC0813 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.04816886431041728 | [468] | [688,546,548,506] | 0 | hSpCas9 | negative selection | 8326073 | 30699985 | 30700008 | 7 | + | 27260156 | PANC0813 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.23161252818376 | [0] | [0,0,0,0] | -4 | hSpCas9 | negative selection | 8390343 | 30699933 | 30699956 | 7 | + | 27260156 | RDES | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.4958645256960661 | [468] | [281,359,275,663] | -7 | hSpCas9 | negative selection | 8447324 | 30699985 | 30700008 | 7 | + | 27260156 | RDES | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.18942035355372333 | [0] | [0,0,0,0] | -3 | hSpCas9 | negative selection | 8511594 | 30699933 | 30699956 | 7 | + | 27260156 | PC3 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.02482934000761084 | [468] | [389,463,640,380] | 0 | hSpCas9 | negative selection | 8568575 | 30699985 | 30700008 | 7 | + | 27260156 | PC3 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.05753347684474441 | [0] | [0,0,0,0] | 1 | hSpCas9 | negative selection | 8632845 | 30699933 | 30699956 | 7 | + | 27260156 | PATU8988T | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.049485861795975576 | [468] | [532,691,474,172] | 0 | hSpCas9 | negative selection | 8689826 | 30699985 | 30700008 | 7 | + | 27260156 | PATU8988T | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.04952519822641044 | [0] | [0,0,0,0] | 0 | hSpCas9 | negative selection | 8754096 | 30699933 | 30699956 | 7 | + | 27260156 | T47D | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.5092586355284143 | [468] | [344,282,401,517] | -8 | hSpCas9 | negative selection | 8811077 | 30699985 | 30700008 | 7 | + | 27260156 | T47D | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.2201891943612022 | [0] | [0,0,0,0] | -5 | hSpCas9 | negative selection | 8875347 | 30699933 | 30699956 | 7 | + | 27260156 | SU8686 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.3518067080195897 | [468] | [477,516,699,720] | 6 | hSpCas9 | negative selection | 8932328 | 30699985 | 30700008 | 7 | + | 27260156 | SU8686 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.015103263740369854 | [0] | [0,0,0,0] | 0 | hSpCas9 | negative selection | 8996598 | 30699933 | 30699956 | 7 | + | 27260156 | SKES1 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.17817715637627754 | [468] | [575,427,435,252] | -4 | hSpCas9 | negative selection | 9053579 | 30699985 | 30700008 | 7 | + | 27260156 | SKES1 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.007546427030755254 | [0] | [0,0,0,0] | 0 | hSpCas9 | negative selection | 9117849 | 30699933 | 30699956 | 7 | + | 27260156 | TOV112D | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | -0.24925495338160047 | [468] | [444,515,400,255] | -5 | hSpCas9 | negative selection | 9174830 | 30699985 | 30700008 | 7 | + | 27260156 | TOV112D | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.0015868904355240687 | [0] | [0,0,0,0] | 0 | hSpCas9 | negative selection | 9239100 | 30699933 | 30699956 | 7 | + | 27260156 | TC71 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.18502082844936987 | [468] | [655,575,533,515] | 4 | hSpCas9 | negative selection | 9296081 | 30699985 | 30700008 | 7 | + | 27260156 | TC71 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | -0.10019163119465624 | [0] | [0,0,0,0] | -3 | hSpCas9 | negative selection | 9360351 | 30699933 | 30699956 | 7 | + | 27260156 | TC32 | viability | CCTGCACTTACGTATTGGAGCGG | INMT | ENSG00000241644 | 0.050833617506231304 | [468] | [345,363,744,442] | 0 | hSpCas9 | negative selection | 9417332 | 30699985 | 30700008 | 7 | + | 27260156 | TC32 | viability | GGAGGTGTGGGACGTAGAGGAGG | INMT | ENSG00000241644 | 0.11232540807230862 | [0] | [0,0,0,0] | 2 | hSpCas9 | negative selection | 9481602 |