Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3643
• Symbol:INSR
• Description:insulin receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/INSR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
7291214	7291237	19	+	26472758	Jiyoye	viability	GGCTCGGACTCAAAAGAACAAAG	INSR	ENSG00000171105	-0.685934022885608	[159]	[74]	-5	hSpCas9	negative selection	46621
7184321	7184344	19	+	26472758	Jiyoye	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	1.2696718577559385	[54]	[99]	7	hSpCas9	negative selection	78567
7170658	7170681	19	+	26472758	Jiyoye	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	1.6727654922434239	[46]	[112]	8	hSpCas9	negative selection	78568
7166306	7166329	19	+	26472758	Jiyoye	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.07786775625291353	[48]	[38]	0	hSpCas9	negative selection	78569
7293792	7293815	19	-	26472758	Jiyoye	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.4496106478262699	[66]	[68]	3	hSpCas9	negative selection	78570
7267636	7267659	19	-	26472758	Jiyoye	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	1.3858017307133066	[33]	[66]	8	hSpCas9	negative selection	78571
7267572	7267595	19	-	26472758	Jiyoye	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.9193815397917154	[121]	[173]	6	hSpCas9	negative selection	78572
7267382	7267405	19	+	26472758	Jiyoye	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	-0.07642640425604202	[157]	[112]	0	hSpCas9	negative selection	78573
7184606	7184629	19	+	26472758	Jiyoye	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.3351641365904854	[266]	[253]	2	hSpCas9	negative selection	78574
7184396	7184419	19	-	26472758	Jiyoye	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-1.8981698291858846	[172]	[34]	-8	hSpCas9	negative selection	78575
7172337	7172360	19	+	26472758	Jiyoye	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	0.6282022608180919	[150]	[175]	4	hSpCas9	negative selection	78576
7291214	7291237	19	+	26472758	KBM7	viability	GGCTCGGACTCAAAAGAACAAAG	INSR	ENSG00000171105	-0.3028351998080857	[473,583]	[180,225]	-3	hSpCas9	negative selection	237739
7184321	7184344	19	+	26472758	KBM7	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.41326419046170726	[447,177]	[229,150]	4	hSpCas9	negative selection	269685
7170658	7170681	19	+	26472758	KBM7	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	0.21347769539548236	[597,479]	[329,257]	2	hSpCas9	negative selection	269686
7166306	7166329	19	+	26472758	KBM7	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.1692609718973963	[194,81]	[69,70]	1	hSpCas9	negative selection	269687
7293792	7293815	19	-	26472758	KBM7	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.5240511273922203	[534,302]	[320,236]	6	hSpCas9	negative selection	269688
7267636	7267659	19	-	26472758	KBM7	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.39094223761320307	[392,291]	[274,149]	4	hSpCas9	negative selection	269689
7267572	7267595	19	-	26472758	KBM7	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.7658512985546178	[701,445]	[588,326]	8	hSpCas9	negative selection	269690
7267382	7267405	19	+	26472758	KBM7	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.8074618521682216	[929,768]	[616,765]	8	hSpCas9	negative selection	269691
7184606	7184629	19	+	26472758	KBM7	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.2485937574027195	[877,1023]	[575,503]	2	hSpCas9	negative selection	269692
7184396	7184419	19	-	26472758	KBM7	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.2576407586244478	[205,166]	[99,107]	2	hSpCas9	negative selection	269693
7172337	7172360	19	+	26472758	KBM7	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	0.2456895634723817	[944,1026]	[418,675]	2	hSpCas9	negative selection	269694
7291214	7291237	19	+	26472758	Raji	viability	GGCTCGGACTCAAAAGAACAAAG	INSR	ENSG00000171105	0.8986660509342281	[244]	[105]	7	hSpCas9	negative selection	428857
7184321	7184344	19	+	26472758	Raji	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.05814001635375032	[148]	[35]	0	hSpCas9	negative selection	460803
7170658	7170681	19	+	26472758	Raji	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-1.6811123594326887	[455]	[32]	-8	hSpCas9	negative selection	460804
7166306	7166329	19	+	26472758	Raji	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.4369369808502108	[69]	[11]	-4	hSpCas9	negative selection	460805
7293792	7293815	19	-	26472758	Raji	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.5593206174639724	[192]	[65]	5	hSpCas9	negative selection	460806
7267636	7267659	19	-	26472758	Raji	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.9417974696556245	[165]	[73]	8	hSpCas9	negative selection	460807
7267572	7267595	19	-	26472758	Raji	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.4811983719259304	[212]	[68]	4	hSpCas9	negative selection	460808
7267382	7267405	19	+	26472758	Raji	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.07668673815068316	[379]	[92]	0	hSpCas9	negative selection	460809
7184606	7184629	19	+	26472758	Raji	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.31202614641558846	[478]	[137]	3	hSpCas9	negative selection	460810
7184396	7184419	19	-	26472758	Raji	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.1902970132670856	[117]	[23]	-2	hSpCas9	negative selection	460811
7172337	7172360	19	+	26472758	Raji	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-0.8071202443447943	[474]	[62]	-6	hSpCas9	negative selection	460812
7291214	7291237	19	+	26472758	K562	viability	GGCTCGGACTCAAAAGAACAAAG	INSR	ENSG00000171105	0.8319100546983419	[379]	[570]	7	hSpCas9	negative selection	619975
7184321	7184344	19	+	26472758	K562	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.8573956045571998	[203]	[311]	7	hSpCas9	negative selection	651921
7170658	7170681	19	+	26472758	K562	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	0.6487457468632899	[506]	[670]	5	hSpCas9	negative selection	651922
7166306	7166329	19	+	26472758	K562	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.25481389902882534	[146]	[103]	-2	hSpCas9	negative selection	651923
7293792	7293815	19	-	26472758	K562	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.3536970689514397	[304]	[328]	2	hSpCas9	negative selection	651924
7267636	7267659	19	-	26472758	K562	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.9334042929308314	[213]	[344]	7	hSpCas9	negative selection	651925
7267572	7267595	19	-	26472758	K562	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.17226894191061162	[368]	[350]	1	hSpCas9	negative selection	651926
7267382	7267405	19	+	26472758	K562	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.5301349376590374	[588]	[717]	4	hSpCas9	negative selection	651927
7184606	7184629	19	+	26472758	K562	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.2157786796225456	[813]	[797]	1	hSpCas9	negative selection	651928
7184396	7184419	19	-	26472758	K562	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.4421827762338562	[210]	[241]	3	hSpCas9	negative selection	651929
7172337	7172360	19	+	26472758	K562	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	0.3900085369800411	[743]	[822]	3	hSpCas9	negative selection	651930
7166200	7166223	19	+	26627737	DLD1	viability	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.11654093739173671	[649]	[180,210,261]	1	hSpCas9	negative selection	807553
7167995	7168018	19	+	26627737	DLD1	viability	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-0.9655858229951062	[171]	[40,1,36]	-7	hSpCas9	negative selection	807554
7172316	7172339	19	+	26627737	DLD1	viability	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.6008384921968021	[610]	[281,318,271]	6	hSpCas9	negative selection	807555
7174611	7174634	19	-	26627737	DLD1	viability	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	1.2742382130984988	[100]	[95,48,81]	9	hSpCas9	negative selection	807556
7184396	7184419	19	-	26627737	DLD1	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.09723452710547065	[596]	[127,313,166]	1	hSpCas9	negative selection	807557
7267572	7267595	19	-	26627737	DLD1	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.21359525471941576	[1915]	[561,518,474]	-2	hSpCas9	negative selection	807559
7166200	7166223	19	+	26627737	GBM cells	viability after 5 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.42189670667953066	[324]	[232,233]	6	hSpCas9	negative selection	889868
7167995	7168018	19	+	26627737	GBM cells	viability after 5 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-0.4162883568133635	[106]	[45,39]	-6	hSpCas9	negative selection	889869
7172316	7172339	19	+	26627737	GBM cells	viability after 5 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.15115622396869344	[491]	[282,302]	2	hSpCas9	negative selection	889870
7174611	7174634	19	-	26627737	GBM cells	viability after 5 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.2360157052004228	[111]	[42,58]	-4	hSpCas9	negative selection	889871
7184396	7184419	19	-	26627737	GBM cells	viability after 5 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.3049737780452719	[402]	[311,221]	5	hSpCas9	negative selection	889872
7267572	7267595	19	-	26627737	GBM cells	viability after 5 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.31429643355361514	[756]	[373,278]	-5	hSpCas9	negative selection	889874
7166200	7166223	19	+	26627737	GBM cells	viability after 13 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.5077015643103433	[324]	[301,208]	6	hSpCas9	negative selection	972183
7167995	7168018	19	+	26627737	GBM cells	viability after 13 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	0.11909425187449818	[106]	[99,32]	1	hSpCas9	negative selection	972184
7172316	7172339	19	+	26627737	GBM cells	viability after 13 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.14875525127437061	[491]	[392,216]	2	hSpCas9	negative selection	972185
7174611	7174634	19	-	26627737	GBM cells	viability after 13 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.1456289931126591	[111]	[60,49]	-2	hSpCas9	negative selection	972186
7184396	7184419	19	-	26627737	GBM cells	viability after 13 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.06718035025330693	[402]	[329,146]	0	hSpCas9	negative selection	972187
7267572	7267595	19	-	26627737	GBM cells	viability after 13 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.4384873235352533	[756]	[328,281]	-5	hSpCas9	negative selection	972189
7166200	7166223	19	+	26627737	GBM cells	viability after 21 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.40773997931516365	[324]	[263,206]	4	hSpCas9	negative selection	1054498
7167995	7168018	19	+	26627737	GBM cells	viability after 21 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-1.4865805708889612	[106]	[14,25]	-8	hSpCas9	negative selection	1054499
7172316	7172339	19	+	26627737	GBM cells	viability after 21 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.18188137477251876	[491]	[255,216]	-2	hSpCas9	negative selection	1054500
7174611	7174634	19	-	26627737	GBM cells	viability after 21 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.361998382593401	[111]	[50,43]	-3	hSpCas9	negative selection	1054501
7184396	7184419	19	-	26627737	GBM cells	viability after 21 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.643860765756813	[402]	[148,131]	-5	hSpCas9	negative selection	1054502
7267572	7267595	19	-	26627737	GBM cells	viability after 21 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.32031677695570115	[756]	[343,315]	-3	hSpCas9	negative selection	1054504
7166200	7166223	19	+	26627737	RPE1	viability after 9 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.6779196073922692	[1058]	[453,628]	4	hSpCas9	negative selection	1136813
7167995	7168018	19	+	26627737	RPE1	viability after 9 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-4.623494149048088	[569]	[1,13]	-9	hSpCas9	negative selection	1136814
7172316	7172339	19	+	26627737	RPE1	viability after 9 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	1.0208396068644912	[1548]	[983,983]	6	hSpCas9	negative selection	1136815
7174611	7174634	19	-	26627737	RPE1	viability after 9 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.8343123739748116	[492]	[86,85]	-5	hSpCas9	negative selection	1136816
7184396	7184419	19	-	26627737	RPE1	viability after 9 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.3452120186419674	[1271]	[240,406]	-2	hSpCas9	negative selection	1136817
7267572	7267595	19	-	26627737	RPE1	viability after 9 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.8869171684984374	[2083]	[261,469]	-6	hSpCas9	negative selection	1136819
7166200	7166223	19	+	26627737	RPE1	viability after 12 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.46925782071390887	[1058]	[355,433]	3	hSpCas9	negative selection	1219128
7167995	7168018	19	+	26627737	RPE1	viability after 12 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-2.65497439263797	[569]	[0,48]	-9	hSpCas9	negative selection	1219129
7172316	7172339	19	+	26627737	RPE1	viability after 12 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.861123355739014	[1548]	[923,577]	5	hSpCas9	negative selection	1219130
7174611	7174634	19	-	26627737	RPE1	viability after 12 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.4859999399551601	[492]	[164,19]	-3	hSpCas9	negative selection	1219131
7184396	7184419	19	-	26627737	RPE1	viability after 12 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.522473451933155	[1271]	[166,312]	-4	hSpCas9	negative selection	1219132
7267572	7267595	19	-	26627737	RPE1	viability after 12 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.8086466290741451	[2083]	[392,241]	-5	hSpCas9	negative selection	1219134
7166200	7166223	19	+	26627737	RPE1	viability after 15 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.4861313117936342	[1058]	[413,424]	3	hSpCas9	negative selection	1301443
7167995	7168018	19	+	26627737	RPE1	viability after 15 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-1.784186318367886	[569]	[0,90]	-8	hSpCas9	negative selection	1301444
7172316	7172339	19	+	26627737	RPE1	viability after 15 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.9304865366952931	[1548]	[1108,570]	5	hSpCas9	negative selection	1301445
7174611	7174634	19	-	26627737	RPE1	viability after 15 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.46545116312677204	[492]	[128,73]	-3	hSpCas9	negative selection	1301446
7184396	7184419	19	-	26627737	RPE1	viability after 15 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.6380574367559068	[1271]	[162,296]	-4	hSpCas9	negative selection	1301447
7267572	7267595	19	-	26627737	RPE1	viability after 15 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-1.1875152782442482	[2083]	[211,303]	-6	hSpCas9	negative selection	1301449
7166200	7166223	19	+	26627737	RPE1	viability after 18 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.4533423909254942	[1058]	[341,443]	3	hSpCas9	negative selection	1383758
7167995	7168018	19	+	26627737	RPE1	viability after 18 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-2.919150851910161	[569]	[0,40]	-9	hSpCas9	negative selection	1383759
7172316	7172339	19	+	26627737	RPE1	viability after 18 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.5097063226773008	[1548]	[570,620]	3	hSpCas9	negative selection	1383760
7174611	7174634	19	-	26627737	RPE1	viability after 18 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.2745401847863568	[492]	[167,47]	-2	hSpCas9	negative selection	1383761
7184396	7184419	19	-	26627737	RPE1	viability after 18 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.610254227440434	[1271]	[89,368]	-4	hSpCas9	negative selection	1383762
7267572	7267595	19	-	26627737	RPE1	viability after 18 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-1.0128211525021547	[2083]	[284,271]	-6	hSpCas9	negative selection	1383764
7166200	7166223	19	+	26627737	HeLa	viability after 8 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.38613401727104346	[448]	[190,381,183]	3	hSpCas9	negative selection	1466073
7167995	7168018	19	+	26627737	HeLa	viability after 8 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-0.7682089205070706	[69]	[22,31,0]	-6	hSpCas9	negative selection	1466074
7172316	7172339	19	+	26627737	HeLa	viability after 8 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.8377511315178833	[415]	[445,323,233]	7	hSpCas9	negative selection	1466075
7174611	7174634	19	-	26627737	HeLa	viability after 8 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-1.2937911535702236	[154]	[2,14,56]	-8	hSpCas9	negative selection	1466076
7184396	7184419	19	-	26627737	HeLa	viability after 8 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	1.101658749960029	[450]	[439,382,442]	8	hSpCas9	negative selection	1466077
7267572	7267595	19	-	26627737	HeLa	viability after 8 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.48908594469052025	[1124]	[363,400,288]	-5	hSpCas9	negative selection	1466079
7166200	7166223	19	+	26627737	HeLa	viability after 12 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.4634677254150871	[448]	[228,300,231]	4	hSpCas9	negative selection	1548388
7167995	7168018	19	+	26627737	HeLa	viability after 12 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	1.037460858638003	[69]	[37,101,32]	7	hSpCas9	negative selection	1548389
7172316	7172339	19	+	26627737	HeLa	viability after 12 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	1.3894705557399882	[415]	[551,413,391]	8	hSpCas9	negative selection	1548390
7174611	7174634	19	-	26627737	HeLa	viability after 12 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.5154007163886495	[154]	[34,157,72]	4	hSpCas9	negative selection	1548391
7184396	7184419	19	-	26627737	HeLa	viability after 12 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	1.0873623237612557	[450]	[637,302,263]	7	hSpCas9	negative selection	1548392
7267572	7267595	19	-	26627737	HeLa	viability after 12 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.022422018910218444	[1124]	[550,230,617]	0	hSpCas9	negative selection	1548394
7166200	7166223	19	+	26627737	HeLa	viability after 15 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.8852789222486718	[448]	[334,411,259]	6	hSpCas9	negative selection	1630703
7167995	7168018	19	+	26627737	HeLa	viability after 15 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	0.6652885041276484	[69]	[119,0,10]	5	hSpCas9	negative selection	1630704
7172316	7172339	19	+	26627737	HeLa	viability after 15 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	1.2727516281041114	[415]	[554,402,255]	8	hSpCas9	negative selection	1630705
7174611	7174634	19	-	26627737	HeLa	viability after 15 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.6244321128292029	[154]	[9,160,123]	5	hSpCas9	negative selection	1630706
7184396	7184419	19	-	26627737	HeLa	viability after 15 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.5034683467629973	[450]	[288,260,227]	4	hSpCas9	negative selection	1630707
7267572	7267595	19	-	26627737	HeLa	viability after 15 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.03401725631199204	[1124]	[666,318,413]	0	hSpCas9	negative selection	1630709
7166200	7166223	19	+	26627737	HeLa	viability after 18 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.9047170840952513	[448]	[232,341,259]	6	hSpCas9	negative selection	1713018
7167995	7168018	19	+	26627737	HeLa	viability after 18 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	0.7547147925705395	[69]	[85,0,10]	6	hSpCas9	negative selection	1713019
7172316	7172339	19	+	26627737	HeLa	viability after 18 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	1.2579170336784495	[415]	[367,328,255]	8	hSpCas9	negative selection	1713020
7174611	7174634	19	-	26627737	HeLa	viability after 18 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.6444265006707361	[154]	[7,134,123]	5	hSpCas9	negative selection	1713021
7184396	7184419	19	-	26627737	HeLa	viability after 18 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.5538661534546372	[450]	[199,230,227]	4	hSpCas9	negative selection	1713022
7267572	7267595	19	-	26627737	HeLa	viability after 18 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.031408917520997504	[1124]	[441,268,413]	0	hSpCas9	negative selection	1713024
7166200	7166223	19	+	26627737	HCT116	viability after 6 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.16178093114467454	[795]	[136,97]	-1	hSpCas9	negative selection	1795333
7167995	7168018	19	+	26627737	HCT116	viability after 6 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-0.03672952775570315	[186]	[76,1]	0	hSpCas9	negative selection	1795334
7172316	7172339	19	+	26627737	HCT116	viability after 6 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.27548289105691515	[1434]	[604,89]	1	hSpCas9	negative selection	1795335
7174611	7174634	19	-	26627737	HCT116	viability after 6 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.194378953024971	[572]	[128,50]	-1	hSpCas9	negative selection	1795336
7184396	7184419	19	-	26627737	HCT116	viability after 6 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.6136316021208476	[995]	[247,21]	-4	hSpCas9	negative selection	1795337
7267572	7267595	19	-	26627737	HCT116	viability after 6 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.676186667753367	[1587]	[230,114]	-4	hSpCas9	negative selection	1795339
7166200	7166223	19	+	26627737	HCT116	viability after 8 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.30871956312387194	[536]	[241,173,299]	-4	hSpCas9	negative selection	1877648
7167995	7168018	19	+	26627737	HCT116	viability after 8 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	1.9467222365677728	[18]	[34,46,38]	9	hSpCas9	negative selection	1877649
7172316	7172339	19	+	26627737	HCT116	viability after 8 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.033775557573927806	[760]	[413,325,487]	0	hSpCas9	negative selection	1877650
7174611	7174634	19	-	26627737	HCT116	viability after 8 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	1.233213616032617	[56]	[40,111,67]	8	hSpCas9	negative selection	1877651
7184396	7184419	19	-	26627737	HCT116	viability after 8 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.388017857218758	[361]	[297,245,239]	4	hSpCas9	negative selection	1877652
7267572	7267595	19	-	26627737	HCT116	viability after 8 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.2152737513948968	[506]	[289,244,435]	2	hSpCas9	negative selection	1877654
7166200	7166223	19	+	26627737	HCT116	viability after 9 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.07271572881190408	[795]	[286,134]	0	hSpCas9	negative selection	1959963
7167995	7168018	19	+	26627737	HCT116	viability after 9 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-1.5644152772250874	[186]	[17,15]	-8	hSpCas9	negative selection	1959964
7172316	7172339	19	+	26627737	HCT116	viability after 9 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.44570852222355284	[1434]	[301,264]	-3	hSpCas9	negative selection	1959965
7174611	7174634	19	-	26627737	HCT116	viability after 9 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.8561375982575611	[572]	[131,46]	-6	hSpCas9	negative selection	1959966
7184396	7184419	19	-	26627737	HCT116	viability after 9 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.21319989027982222	[995]	[420,77]	-1	hSpCas9	negative selection	1959967
7267572	7267595	19	-	26627737	HCT116	viability after 9 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.9167681210841678	[1587]	[256,198]	-6	hSpCas9	negative selection	1959969
7166200	7166223	19	+	26627737	HCT116	viability after 12 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.5125937200484691	[536]	[230,216,142]	-5	hSpCas9	negative selection	2042278
7167995	7168018	19	+	26627737	HCT116	viability after 12 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	0.9872458881969468	[18]	[21,11,24]	8	hSpCas9	negative selection	2042279
7172316	7172339	19	+	26627737	HCT116	viability after 12 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.5616028215792965	[760]	[285,287,237]	-6	hSpCas9	negative selection	2042280
7174611	7174634	19	-	26627737	HCT116	viability after 12 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.6194351370223221	[56]	[24,49,64]	6	hSpCas9	negative selection	2042281
7184396	7184419	19	-	26627737	HCT116	viability after 12 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.11637494324962955	[361]	[258,168,90]	-1	hSpCas9	negative selection	2042282
7267572	7267595	19	-	26627737	HCT116	viability after 12 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.3523592914520477	[506]	[193,191,240]	-4	hSpCas9	negative selection	2042284
7166200	7166223	19	+	26627737	HCT116	viability after 15 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.7972778871575282	[536]	[196,179,157]	-7	hSpCas9	negative selection	2124593
7167995	7168018	19	+	26627737	HCT116	viability after 15 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-0.1986381995533515	[18]	[28,0,0]	-2	hSpCas9	negative selection	2124594
7172316	7172339	19	+	26627737	HCT116	viability after 15 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.22059973300306557	[760]	[402,299,424]	-2	hSpCas9	negative selection	2124595
7174611	7174634	19	-	26627737	HCT116	viability after 15 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.9215932352072274	[56]	[86,34,66]	7	hSpCas9	negative selection	2124596
7184396	7184419	19	-	26627737	HCT116	viability after 15 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.10095542174836097	[361]	[287,264,124]	1	hSpCas9	negative selection	2124597
7267572	7267595	19	-	26627737	HCT116	viability after 15 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.0956313682376656	[506]	[353,224,358]	1	hSpCas9	negative selection	2124599
7166200	7166223	19	+	26627737	HCT116	viability after 18 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.6987676640681642	[536]	[165,138,176]	-6	hSpCas9	negative selection	2206908
7167995	7168018	19	+	26627737	HCT116	viability after 18 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	1.0872543526547984	[18]	[25,12,19]	8	hSpCas9	negative selection	2206909
7172316	7172339	19	+	26627737	HCT116	viability after 18 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.19189740943923517	[760]	[297,239,438]	-2	hSpCas9	negative selection	2206910
7174611	7174634	19	-	26627737	HCT116	viability after 18 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	1.044396428596743	[56]	[135,2,33]	7	hSpCas9	negative selection	2206911
7184396	7184419	19	-	26627737	HCT116	viability after 18 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.6229827884320489	[361]	[271,281,252]	5	hSpCas9	negative selection	2206912
7267572	7267595	19	-	26627737	HCT116	viability after 18 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.22244621821107957	[506]	[312,179,375]	2	hSpCas9	negative selection	2206914
7267846	7267869	19	-	24336569	HL60	viability	CCTCACTAGGTTGCATGAGCTGG	INSR	ENSG00000171105	0.6415377721642876	[570]	[1884]	5	hSpCas9	negative selection	2271765
7267855	7267878	19	+	24336569	HL60	viability	GCAACCTAGTGAGGTTGTTCCGG	INSR	ENSG00000171105	0.4786105950852898	[954]	[2815]	4	hSpCas9	negative selection	2271766
7267868	7267891	19	+	24336569	HL60	viability	GTTGTTCCGGATATCCATGCCGG	INSR	ENSG00000171105	-0.933757942723359	[806]	[893]	-7	hSpCas9	negative selection	2271767
7267874	7267897	19	-	24336569	HL60	viability	TGTGTCCCGGCATGGATATCCGG	INSR	ENSG00000171105	0.3965423202590759	[904]	[2520]	3	hSpCas9	negative selection	2271768
7267882	7267905	19	-	24336569	HL60	viability	TCTTGTAGTGTGTCCCGGCATGG	INSR	ENSG00000171105	1.453008629638567	[188]	[1094]	8	hSpCas9	negative selection	2271769
7293812	7293835	19	-	24336569	HL60	viability	GCGCTGCTACTGGGCGCCGCGGG	INSR	ENSG00000171105	0.5108653695004728	[585]	[1766]	4	hSpCas9	negative selection	2271770
7293821	7293844	19	-	24336569	HL60	viability	GCGGTGGCCGCGCTGCTACTGGG	INSR	ENSG00000171105	-1.1790355872992966	[366]	[342]	-8	hSpCas9	negative selection	2271771
7293833	7293856	19	+	24336569	HL60	viability	GCGGCCACCGCCACCAGCAGCGG	INSR	ENSG00000171105	0.21144510078692846	[461]	[1131]	2	hSpCas9	negative selection	2271772
7293838	7293861	19	+	24336569	HL60	viability	CACCGCCACCAGCAGCGGCGCGG	INSR	ENSG00000171105	-0.0997216847250113	[993]	[1962]	-1	hSpCas9	negative selection	2271773
7293880	7293903	19	-	24336569	HL60	viability	CTCCCGCAGCCATGGCCACCGGG	INSR	ENSG00000171105	0.4011936373209968	[744]	[2081]	3	hSpCas9	negative selection	2271774
7267846	7267869	19	-	24336569	KBM7	viability	CCTCACTAGGTTGCATGAGCTGG	INSR	ENSG00000171105	0.9989928189024349	[460]	[2512]	8	hSpCas9	negative selection	2338942
7267855	7267878	19	+	24336569	KBM7	viability	GCAACCTAGTGAGGTTGTTCCGG	INSR	ENSG00000171105	0.48164772903773656	[845]	[3221]	4	hSpCas9	negative selection	2338943
7267868	7267891	19	+	24336569	KBM7	viability	GTTGTTCCGGATATCCATGCCGG	INSR	ENSG00000171105	-0.0902174081669357	[369]	[947]	-1	hSpCas9	negative selection	2338944
7267874	7267897	19	-	24336569	KBM7	viability	TGTGTCCCGGCATGGATATCCGG	INSR	ENSG00000171105	0.49630071711921675	[746]	[2873]	4	hSpCas9	negative selection	2338945
7267882	7267905	19	-	24336569	KBM7	viability	TCTTGTAGTGTGTCCCGGCATGG	INSR	ENSG00000171105	0.9002214235054855	[209]	[1068]	7	hSpCas9	negative selection	2338946
7293812	7293835	19	-	24336569	KBM7	viability	GCGCTGCTACTGGGCGCCGCGGG	INSR	ENSG00000171105	0.5747453501225718	[512]	[2083]	5	hSpCas9	negative selection	2338947
7293821	7293844	19	-	24336569	KBM7	viability	GCGGTGGCCGCGCTGCTACTGGG	INSR	ENSG00000171105	-1.8089156759944802	[166]	[129]	-8	hSpCas9	negative selection	2338948
7293833	7293856	19	+	24336569	KBM7	viability	GCGGCCACCGCCACCAGCAGCGG	INSR	ENSG00000171105	0.020279220758237543	[418]	[1158]	0	hSpCas9	negative selection	2338949
7293838	7293861	19	+	24336569	KBM7	viability	CACCGCCACCAGCAGCGGCGCGG	INSR	ENSG00000171105	0.5571016257664174	[1076]	[4321]	5	hSpCas9	negative selection	2338950
7293880	7293903	19	-	24336569	KBM7	viability	CTCCCGCAGCCATGGCCACCGGG	INSR	ENSG00000171105	0.2769729777090173	[711]	[2352]	2	hSpCas9	negative selection	2338951
7259187	7259210	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	AAAAAGAAAGGAAGGAAGGAGGG	INSR	ENSG00000171105	0.7713380779136665	[50,170]	[43,39]	3	dCas9-VP64	positive selection	2385764
7132665	7132688	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCTGCCTCCCGGG	INSR	ENSG00000171105	-0.8346021834980462	[246,704]	[74,41]	-5	dCas9-VP64	positive selection	2386303
7208907	7208930	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACAGGG	INSR	ENSG00000171105	6.121120684117956	[31,90]	[7,1976]	9	dCas9-VP64	positive selection	2387406
7138036	7138059	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAAGCTCCACCTCCTGG	INSR	ENSG00000171105	-1.3954490623194618	[659,580]	[75,24]	-7	dCas9-VP64	positive selection	2391151
7213226	7213249	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTTGGCAGGCTGAGG	INSR	ENSG00000171105	2.180224224283918	[67,41]	[97,7]	7	dCas9-VP64	positive selection	2393007
7249897	7249920	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGAATCACTTGAGCCCAAG	INSR	ENSG00000171105	1.6338811116880798	[2,7]	[1,4]	6	dCas9-VP64	positive selection	2394836
7138159	7138182	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCGTGTTAGCCAGGATGG	INSR	ENSG00000171105	0.2955844688889684	[184,570]	[130,72]	1	dCas9-VP64	positive selection	2398562
7277829	7277852	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGCACTTCAG	INSR	ENSG00000171105	-0.9680503266497309	[486,330]	[14,78]	-5	dCas9-VP64	positive selection	2398760
7245009	7245032	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAAGCTCCGCCTCCCAAG	INSR	ENSG00000171105	0.20407356943453547	[198,395]	[107,39]	1	dCas9-VP64	positive selection	2401822
7123805	7123828	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCAGGAGGCCGCGG	INSR	ENSG00000171105	1.2848086487689858	[4,11]	[0,7]	5	dCas9-VP64	positive selection	2402917
7176473	7176496	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCTACTGGG	INSR	ENSG00000171105	-0.8190110364213175	[438,580]	[39,87]	-4	dCas9-VP64	positive selection	2406386
7253952	7253975	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCTCCCAG	INSR	ENSG00000171105	-2.007733074360467	[162,472]	[3,30]	-9	dCas9-VP64	positive selection	2423934
7237239	7237262	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCGCGTCTGG	INSR	ENSG00000171105	-0.7423063429264437	[17,121]	[9,7]	-4	dCas9-VP64	positive selection	2425733
7257132	7257155	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACTATGTTGGCCCAG	INSR	ENSG00000171105	-1.5948665931662949	[72,13]	[3,0]	-8	dCas9-VP64	positive selection	2426167
7197580	7197603	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGTGTGTGTGTGTGTGTGTCAG	INSR	ENSG00000171105	4.847110262494055	[32,12]	[264,23]	9	dCas9-VP64	positive selection	2428731
7149592	7149615	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGGCGGATCGCCTGAGGTCGGG	INSR	ENSG00000171105	6.867551394174825	[8,20]	[680,118]	9	dCas9-VP64	positive selection	2432017
7248900	7248923	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGCGCCACCACGCCCAG	INSR	ENSG00000171105	0.7395023947734947	[14,26]	[11,2]	3	dCas9-VP64	positive selection	2436148
7186746	7186769	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGCCACTGCACCCCAGCCTGG	INSR	ENSG00000171105	0.36632392651586576	[208,84]	[58,21]	1	dCas9-VP64	positive selection	2442368
7202572	7202595	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTGCAACCTCTGCCCCCGGG	INSR	ENSG00000171105	-1.2513288674205318	[297,436]	[21,46]	-7	dCas9-VP64	positive selection	2446523
7240523	7240546	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCATTGCACTCCAGCCAGG	INSR	ENSG00000171105	3.359380449218091	[189,5]	[417,3]	8	dCas9-VP64	positive selection	2446650
7185563	7185586	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGTGAGCCACCACACCGAG	INSR	ENSG00000171105	0.08350517940301261	[638,11]	[141,1]	0	dCas9-VP64	positive selection	2447509
7236790	7236813	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGCGGATCATGAGG	INSR	ENSG00000171105	2.380764290213614	[15,14]	[27,6]	7	dCas9-VP64	positive selection	2449510
7277586	7277609	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGGCTGGTCTTGAACTCCCGG	INSR	ENSG00000171105	1.1112377139242877	[89,193]	[7,132]	4	dCas9-VP64	positive selection	2451682
7149591	7149614	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGCGGATCGCCTGAGGTCGG	INSR	ENSG00000171105	-0.18430104662994673	[168,33]	[5,32]	0	dCas9-VP64	positive selection	2452015
7280672	7280695	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	ATGCCATTGCACTCCAGCCTGGG	INSR	ENSG00000171105	2.033062228314259	[28,209]	[4,221]	7	dCas9-VP64	positive selection	2456484
7284566	7284589	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACCCAGGCTGGAGTGCAGAGG	INSR	ENSG00000171105	-0.014347572194705283	[459,63]	[82,26]	0	dCas9-VP64	positive selection	2457948
7180412	7180435	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCAGGAGGCTGTGG	INSR	ENSG00000171105	1.0101159834039155	[15,74]	[1,39]	4	dCas9-VP64	positive selection	2458866
7191703	7191726	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCCGAGTAGCTGGGACTATTGG	INSR	ENSG00000171105	-1.652200712598355	[99,148]	[10,4]	-8	dCas9-VP64	positive selection	2460278
7205017	7205040	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAGGTTGCGGTGAGCCGAGAAGG	INSR	ENSG00000171105	2.3233621518244867	[14,12]	[9,20]	7	dCas9-VP64	positive selection	2460588
7277898	7277921	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGGGTTTCACCATGTTGGCCTGG	INSR	ENSG00000171105	2.4187836580270234	[16,66]	[4,98]	7	dCas9-VP64	positive selection	2461484
7191044	7191067	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCGTGG	INSR	ENSG00000171105	-0.9342473761319348	[1,66]	[1,4]	-5	dCas9-VP64	positive selection	2466405
7289686	7289709	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTGAGCCACTGCACCCGGCCGAG	INSR	ENSG00000171105	1.1797326428655701	[26,26]	[14,10]	4	dCas9-VP64	positive selection	2469473
7275089	7275112	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACCAACTACTCGGGAGGCTGAGG	INSR	ENSG00000171105	-0.5304241382685226	[52,15]	[7,0]	-3	dCas9-VP64	positive selection	2474370
7259187	7259210	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	AAAAAGAAAGGAAGGAAGGAGGG	INSR	ENSG00000171105	0.04576036968693814	[57,135]	[23,38]	0	dCas9-VP64	positive selection	2481019
7132665	7132688	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCTGCCTCCCGGG	INSR	ENSG00000171105	0.6564409522361534	[325,125]	[135,99]	5	dCas9-VP64	positive selection	2481558
7208907	7208930	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACAGGG	INSR	ENSG00000171105	1.1434369151352513	[54,74]	[73,20]	7	dCas9-VP64	positive selection	2482661
7138036	7138059	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAAGCTCCACCTCCTGG	INSR	ENSG00000171105	0.22022123063307442	[237,267]	[67,121]	1	dCas9-VP64	positive selection	2486406
7213226	7213249	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTTGGCAGGCTGAGG	INSR	ENSG00000171105	0.5215654761973469	[134,134]	[72,52]	4	dCas9-VP64	positive selection	2488262
7249897	7249920	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGAATCACTTGAGCCCAAG	INSR	ENSG00000171105	0.9117627085384212	[38,78]	[28,41]	6	dCas9-VP64	positive selection	2490091
7138159	7138182	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCGTGTTAGCCAGGATGG	INSR	ENSG00000171105	1.071805523628855	[383,191]	[227,172]	7	dCas9-VP64	positive selection	2493817
7277829	7277852	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGCACTTCAG	INSR	ENSG00000171105	0.18483027177666878	[252,653]	[84,243]	1	dCas9-VP64	positive selection	2494015
7245009	7245032	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAAGCTCCGCCTCCCAAG	INSR	ENSG00000171105	4.4236004262517	[85,230]	[22,2123]	9	dCas9-VP64	positive selection	2497077
7123805	7123828	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCAGGAGGCCGCGG	INSR	ENSG00000171105	-0.42778639369274607	[66,93]	[18,18]	-4	dCas9-VP64	positive selection	2498172
7176473	7176496	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCTACTGGG	INSR	ENSG00000171105	0.2665454673496357	[718,321]	[136,269]	2	dCas9-VP64	positive selection	2501641
7253952	7253975	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCTCCCAG	INSR	ENSG00000171105	2.233334387673139	[58,128]	[217,75]	8	dCas9-VP64	positive selection	2519189
7237239	7237262	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCGCGTCTGG	INSR	ENSG00000171105	0.04080549521603816	[105,72]	[24,33]	0	dCas9-VP64	positive selection	2520988
7257132	7257155	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACTATGTTGGCCCAG	INSR	ENSG00000171105	-1.232765897461272	[137,17]	[14,5]	-9	dCas9-VP64	positive selection	2521422
7197580	7197603	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGTGTGTGTGTGTGTGTGTCAG	INSR	ENSG00000171105	0.8889753160498469	[90,141]	[86,53]	6	dCas9-VP64	positive selection	2523986
7149592	7149615	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGGCGGATCGCCTGAGGTCGGG	INSR	ENSG00000171105	2.8861339131047825	[53,23]	[20,163]	9	dCas9-VP64	positive selection	2527272
7248900	7248923	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGCGCCACCACGCCCAG	INSR	ENSG00000171105	0.19409034858978108	[82,214]	[36,71]	1	dCas9-VP64	positive selection	2531403
7186746	7186769	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGCCACTGCACCCCAGCCTGG	INSR	ENSG00000171105	-0.6605575882505516	[226,108]	[36,31]	-6	dCas9-VP64	positive selection	2537623
7202572	7202595	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTGCAACCTCTGCCCCCGGG	INSR	ENSG00000171105	0.4244343490827851	[184,278]	[65,133]	3	dCas9-VP64	positive selection	2541778
7240523	7240546	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCATTGCACTCCAGCCAGG	INSR	ENSG00000171105	0.626840615877442	[158,168]	[52,109]	4	dCas9-VP64	positive selection	2541905
7185563	7185586	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGTGAGCCACCACACCGAG	INSR	ENSG00000171105	-0.14914508695783546	[201,22]	[49,17]	-1	dCas9-VP64	positive selection	2542764
7236790	7236813	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGCGGATCATGAGG	INSR	ENSG00000171105	-0.5827611893698842	[46,84]	[8,17]	-6	dCas9-VP64	positive selection	2544765
7277586	7277609	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGGCTGGTCTTGAACTCCCGG	INSR	ENSG00000171105	-0.05379639634842043	[67,143]	[20,43]	0	dCas9-VP64	positive selection	2546937
7149591	7149614	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGCGGATCGCCTGAGGTCGG	INSR	ENSG00000171105	1.078969245028043	[31,25]	[25,14]	7	dCas9-VP64	positive selection	2547270
7280672	7280695	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	ATGCCATTGCACTCCAGCCTGGG	INSR	ENSG00000171105	0.2042793589460996	[254,297]	[44,158]	1	dCas9-VP64	positive selection	2551739
7284566	7284589	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACCCAGGCTGGAGTGCAGAGG	INSR	ENSG00000171105	-0.8839666549432982	[334,175]	[40,48]	-8	dCas9-VP64	positive selection	2553203
7180412	7180435	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCAGGAGGCTGTGG	INSR	ENSG00000171105	-0.13736370075198145	[6,190]	[3,51]	-1	dCas9-VP64	positive selection	2554121
7191703	7191726	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCCGAGTAGCTGGGACTATTGG	INSR	ENSG00000171105	-0.7864950913442017	[144,106]	[22,23]	-7	dCas9-VP64	positive selection	2555533
7205017	7205040	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAGGTTGCGGTGAGCCGAGAAGG	INSR	ENSG00000171105	1.0057399992234806	[75,12]	[21,35]	6	dCas9-VP64	positive selection	2555843
7277898	7277921	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGGGTTTCACCATGTTGGCCTGG	INSR	ENSG00000171105	0.6489514996892785	[92,108]	[43,57]	5	dCas9-VP64	positive selection	2556739
7191044	7191067	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCGTGG	INSR	ENSG00000171105	0.9976288697164769	[174,155]	[180,39]	6	dCas9-VP64	positive selection	2561660
7289686	7289709	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTGAGCCACTGCACCCGGCCGAG	INSR	ENSG00000171105	0.8568341606696415	[42,16]	[22,11]	6	dCas9-VP64	positive selection	2564728
7275089	7275112	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACCAACTACTCGGGAGGCTGAGG	INSR	ENSG00000171105	-0.09188539124364214	[49,15]	[10,8]	0	dCas9-VP64	positive selection	2569625
7167969	7167992	19	-	27013184	SW480	treatment with recombinant TRAIL	GTTCATGCTGTTCTACAAAGAGG	INSR	ENSG00000171105	-0.4187346414644446	[317,312]	[32,199]	-2	hSpCas9	positive selection	2964384
7122868	7122891	19	+	27013184	SW480	treatment with recombinant TRAIL	AAGCAGCTTACCTCAGCCTCTGG	INSR	ENSG00000171105	0.21827306224306162	[224,219]	[143,65]	1	hSpCas9	positive selection	2964385
7122862	7122885	19	-	27013184	SW480	treatment with recombinant TRAIL	GCTGAGGTAAGCTGCTTCGGGGG	INSR	ENSG00000171105	2.2134394355494207	[556,783]	[1024,1743]	8	hSpCas9	positive selection	2964386
7122863	7122886	19	-	27013184	SW480	treatment with recombinant TRAIL	GGCTGAGGTAAGCTGCTTCGGGG	INSR	ENSG00000171105	0.3240341847470074	[465,532]	[195,370]	1	hSpCas9	positive selection	2964387
7122864	7122887	19	-	27013184	SW480	treatment with recombinant TRAIL	AGGCTGAGGTAAGCTGCTTCGGG	INSR	ENSG00000171105	0.828029877930142	[161,121]	[72,162]	4	hSpCas9	positive selection	2964388
7122865	7122888	19	-	27013184	SW480	treatment with recombinant TRAIL	GAGGCTGAGGTAAGCTGCTTCGG	INSR	ENSG00000171105	-2.1390367073142844	[308,458]	[50,16]	-7	hSpCas9	positive selection	2964389
7122891	7122914	19	-	27013184	SW480	treatment with recombinant TRAIL	AGAGCTACCTCCGTTCTCTGCGG	INSR	ENSG00000171105	-0.2314003378033026	[88,137]	[49,27]	-1	hSpCas9	positive selection	2964390
7122896	7122919	19	+	27013184	SW480	treatment with recombinant TRAIL	GAGAACGGAGGTAGCTCTTCAGG	INSR	ENSG00000171105	1.5752718622492965	[202,242]	[203,398]	7	hSpCas9	positive selection	2964391
7122922	7122945	19	-	27013184	SW480	treatment with recombinant TRAIL	GTGATGGAGCTGATGGCTCACGG	INSR	ENSG00000171105	0.7297910548279847	[95,150]	[65,115]	3	hSpCas9	positive selection	2964392
7122938	7122961	19	-	27013184	SW480	treatment with recombinant TRAIL	CCAGCCCACGCTGGTGGTGATGG	INSR	ENSG00000171105	-0.19174013042191482	[196,210]	[42,124]	-1	hSpCas9	positive selection	2964393
7122961	7122984	19	-	27013184	SW480	treatment with recombinant TRAIL	CTCCTGGGAGTGGTGTCCAAGGG	INSR	ENSG00000171105	1.92926526437058	[67,22]	[23,154]	8	hSpCas9	positive selection	2964394
7122962	7122985	19	-	27013184	SW480	treatment with recombinant TRAIL	CCTCCTGGGAGTGGTGTCCAAGG	INSR	ENSG00000171105	2.9737176546098816	[420,661]	[1663,1991]	9	hSpCas9	positive selection	2964395
7122933	7122956	19	+	27013184	SW480	treatment with recombinant TRAIL	CAGCTCCATCACCACCAGCGTGG	INSR	ENSG00000171105	-0.46340326239698537	[218,286]	[102,42]	-2	hSpCas9	positive selection	2964396
7122934	7122957	19	+	27013184	SW480	treatment with recombinant TRAIL	AGCTCCATCACCACCAGCGTGGG	INSR	ENSG00000171105	1.545470279016563	[347,456]	[516,477]	7	hSpCas9	positive selection	2964397
7122938	7122961	19	+	27013184	SW480	treatment with recombinant TRAIL	CCATCACCACCAGCGTGGGCTGG	INSR	ENSG00000171105	0.052150800432225974	[135,49]	[58,20]	0	hSpCas9	positive selection	2964398
7122959	7122982	19	+	27013184	SW480	treatment with recombinant TRAIL	GGCCCTTGGACACCACTCCCAGG	INSR	ENSG00000171105	0.14041888017918214	[665,1013]	[281,548]	0	hSpCas9	positive selection	2964399
7122962	7122985	19	+	27013184	SW480	treatment with recombinant TRAIL	CCTTGGACACCACTCCCAGGAGG	INSR	ENSG00000171105	2.700807690255169	[295,288]	[667,1039]	9	hSpCas9	positive selection	2964400
7267855	7267878	19	+	27013184	SW480	treatment with recombinant TRAIL	GCAACCTAGTGAGGTTGTTCCGG	INSR	ENSG00000171105	0.7718552226924376	[535,804]	[483,486]	4	hSpCas9	positive selection	2964401
7267868	7267891	19	+	27013184	SW480	treatment with recombinant TRAIL	GTTGTTCCGGATATCCATGCCGG	INSR	ENSG00000171105	-0.13918109917325416	[86,152]	[75,2]	0	hSpCas9	positive selection	2964402
7293778	7293801	19	+	27013184	SW480	treatment with recombinant TRAIL	GCCCCCAGACTCACCCTCTCCGG	INSR	ENSG00000171105	0.6052213891466007	[524,701]	[430,349]	3	hSpCas9	positive selection	2964403
7293779	7293802	19	+	27013184	SW480	treatment with recombinant TRAIL	CCCCCAGACTCACCCTCTCCGGG	INSR	ENSG00000171105	-0.041256601814506855	[550,676]	[165,381]	0	hSpCas9	positive selection	2964404
7293780	7293803	19	+	27013184	SW480	treatment with recombinant TRAIL	CCCCAGACTCACCCTCTCCGGGG	INSR	ENSG00000171105	0.5662212717556282	[185,67]	[48,134]	3	hSpCas9	positive selection	2964405
7293786	7293809	19	+	27013184	SW480	treatment with recombinant TRAIL	ACTCACCCTCTCCGGGGTACAGG	INSR	ENSG00000171105	0.8744603342648407	[136,243]	[115,190]	4	hSpCas9	positive selection	2964406
7293789	7293812	19	+	27013184	SW480	treatment with recombinant TRAIL	CACCCTCTCCGGGGTACAGGTGG	INSR	ENSG00000171105	1.5311590834642055	[128,88]	[119,163]	7	hSpCas9	positive selection	2964407
7267336	7267359	19	-	27013184	SW480	treatment with recombinant TRAIL	TCACTGCCAGAAAGGTACGCCGG	INSR	ENSG00000171105	0.6470745186857687	[56,82]	[48,42]	3	hSpCas9	positive selection	2964408
7267367	7267390	19	-	27013184	SW480	treatment with recombinant TRAIL	GGCAGTTTGTCGAACGATGTTGG	INSR	ENSG00000171105	0.004750138314161267	[406,417]	[191,158]	0	hSpCas9	positive selection	2964409
7267572	7267595	19	-	27013184	SW480	treatment with recombinant TRAIL	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	1.4823433236171462	[464,818]	[419,1231]	6	hSpCas9	positive selection	2964410
7267492	7267515	19	+	27013184	SW480	treatment with recombinant TRAIL	CCTCCACGGAATCCAGGATACGG	INSR	ENSG00000171105	0.5041864193686038	[72,134]	[49,78]	2	hSpCas9	positive selection	2964412
7267824	7267847	19	-	27013184	SW480	treatment with recombinant TRAIL	GAGAATTGCTCTGTCATCGAAGG	INSR	ENSG00000171105	1.8846394324740792	[333,446]	[345,995]	8	hSpCas9	positive selection	2964413
7267508	7267531	19	+	27013184	SW480	treatment with recombinant TRAIL	GATACGGGACCAGTCGATAGTGG	INSR	ENSG00000171105	3.363705644104032	[16,39]	[171,50]	9	hSpCas9	positive selection	2964414
7184396	7184419	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.03228235270917343	[4,4]	[4,2]	0	hSpCas9	positive selection	2995724
7184323	7184346	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAATTCATCGTGTACCCGGAGGG	INSR	ENSG00000171105	0.08389822528950502	[1,2]	[2,1]	1	hSpCas9	positive selection	2995725
7172401	7172424	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGAGCTAGAAGCCAACCTCGG	INSR	ENSG00000171105	-0.6704965970638497	[2,3]	[0,1]	-7	hSpCas9	positive selection	2995726
7166343	7166366	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTGTGGTTCCAACAGTTGGACGG	INSR	ENSG00000171105	0.28092567629979814	[3,3]	[3,4]	6	hSpCas9	positive selection	2995727
7184396	7184419	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.5491071444785953	[4,4]	[3,0]	-7	hSpCas9	positive selection	3063582
7184323	7184346	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAATTCATCGTGTACCCGGAGGG	INSR	ENSG00000171105	0.3331725408203107	[1,1]	[2,0]	6	hSpCas9	positive selection	3063583
7172401	7172424	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGAGCTAGAAGCCAACCTCGG	INSR	ENSG00000171105	-0.24135275301317197	[2,2]	[1,1]	-4	hSpCas9	positive selection	3063584
7166343	7166366	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTGTGGTTCCAACAGTTGGACGG	INSR	ENSG00000171105	0.20612765812969736	[3,3]	[3,2]	3	hSpCas9	positive selection	3063585
7172348	7172371		-	24336571	A375	resistance to PLX after 7 days	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.2672415226555067	[9,10]	[7,9]	-7	hSpCas9	positive selection	3121325
7184530	7184553		-	24336571	A375	resistance to PLX after 7 days	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.02944937820385407	[29,29]	[27,29]	-1	hSpCas9	positive selection	3121326
7172309	7172332		+	24336571	A375	resistance to PLX after 7 days	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.20711229506714068	[32,29]	[28,25]	-6	hSpCas9	positive selection	3121327
7172348	7172371		-	24336571	A375	resistance to PLX after 14 days	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.4993119833445724	[10,13]	[4,2]	-6	hSpCas9	positive selection	3179118
7184530	7184553		-	24336571	A375	resistance to PLX after 14 days	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.5633501265424157	[29,32]	[7,10]	-6	hSpCas9	positive selection	3179119
7172309	7172332		+	24336571	A375	resistance to PLX after 14 days	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-1.0023194688410988	[28,41]	[7,7]	-9	hSpCas9	positive selection	3179120
7172348	7172371		-	24336571	A375	viability after 7 days	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.8893725829275146	[21]	[9,10]	-8	hSpCas9	negative selection	3236911
7184530	7184553		-	24336571	A375	viability after 7 days	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.07061789637279747	[32]	[29,29]	-1	hSpCas9	negative selection	3236912
7172309	7172332		+	24336571	A375	viability after 7 days	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.03807595577381129	[31]	[32,29]	0	hSpCas9	negative selection	3236913
7172348	7172371		-	24336571	A375	viability after 14 days	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.728343713172669	[21]	[10,13]	-7	hSpCas9	negative selection	3294704
7184530	7184553		-	24336571	A375	viability after 14 days	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.03162014568460614	[32]	[29,32]	0	hSpCas9	negative selection	3294705
7172309	7172332		+	24336571	A375	viability after 14 days	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.21254909638724007	[31]	[28,41]	2	hSpCas9	negative selection	3294706
7184519	7184542	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	6.780336221424234	[340,340]	[244,244]	9	hSpCas9	positive selection	3374446
7170564	7170587	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.7370272254130229	[254,254]	[0,0]	-5	hSpCas9	positive selection	3374447
7170669	7170692	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	-1.422153888059611	[409,409]	[0,0]	-8	hSpCas9	positive selection	3374448
7184396	7184419	19	-	26780180	HT29	viability (Avana library 4 designs)	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	2.13230547607432	[]	[]	7	hSpCas9	negative selection	3433105
7184322	7184345	19	+	26780180	HT29	viability (Avana library 4 designs)	GAATTCATCGTGTACCCGGAGGG	INSR	ENSG00000171105	2.28217597002693	[]	[]	7	hSpCas9	negative selection	3433106
7172401	7172424	19	-	26780180	HT29	viability (Avana library 4 designs)	GCTGAGCTAGAAGCCAACCTCGG	INSR	ENSG00000171105	2.67697383134668	[]	[]	8	hSpCas9	negative selection	3433107
7166343	7166366	19	-	26780180	HT29	viability (Avana library 4 designs)	GTGTGGTTCCAACAGTTGGACGG	INSR	ENSG00000171105	1.63647169768519	[]	[]	6	hSpCas9	negative selection	3433108
7184396	7184419	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-6.76841545070855	[]	[]	-6	hSpCas9	negative selection	3519560
7184322	7184345	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAATTCATCGTGTACCCGGAGGG	INSR	ENSG00000171105	3.19148079699186	[]	[]	5	hSpCas9	negative selection	3519561
7172401	7172424	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAGCTAGAAGCCAACCTCGG	INSR	ENSG00000171105	5.28833550554064	[]	[]	8	hSpCas9	negative selection	3519562
7166343	7166366	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTGTGGTTCCAACAGTTGGACGG	INSR	ENSG00000171105	2.63456567954607	[]	[]	4	hSpCas9	negative selection	3519563
7184610	7184633	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCGACCATCTGTAAGTCACACGG	INSR	ENSG00000171105	-2.48524085266554	[]	[]	-3	hSpCas9	negative selection	3519564
7184606	7184629	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-2.11660514055979	[]	[]	-3	hSpCas9	negative selection	3519565
7184396	7184419	19	-	26780180	A375	viability (Avana lentiGuide)	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	2.00229679079694	[]	[]	2	hSpCas9	negative selection	3628219
7184322	7184345	19	+	26780180	A375	viability (Avana lentiGuide)	GAATTCATCGTGTACCCGGAGGG	INSR	ENSG00000171105	2.8753915717976	[]	[]	3	hSpCas9	negative selection	3628220
7172401	7172424	19	-	26780180	A375	viability (Avana lentiGuide)	GCTGAGCTAGAAGCCAACCTCGG	INSR	ENSG00000171105	1.50463940604094	[]	[]	1	hSpCas9	negative selection	3628221
7166343	7166366	19	-	26780180	A375	viability (Avana lentiGuide)	GTGTGGTTCCAACAGTTGGACGG	INSR	ENSG00000171105	-3.42195663559244	[]	[]	-6	hSpCas9	negative selection	3628222
7184610	7184633	19	-	26780180	A375	viability (Avana lentiGuide)	CCGACCATCTGTAAGTCACACGG	INSR	ENSG00000171105	13.7331592669424	[]	[]	7	hSpCas9	negative selection	3628223
7184606	7184629	19	+	26780180	A375	viability (Avana lentiGuide)	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	5.38453905775253	[]	[]	5	hSpCas9	negative selection	3628224
7184396	7184419	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.5058654788562446	[6]	[3,3]	-6	hSpCas9	positive selection	3736878
7184322	7184345	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAATTCATCGTGTACCCGGAGGG	INSR	ENSG00000171105	-0.32920846764956135	[4]	[5,1]	-5	hSpCas9	positive selection	3736879
7172401	7172424	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAGCTAGAAGCCAACCTCGG	INSR	ENSG00000171105	0.09961356103049324	[4]	[3,4]	2	hSpCas9	positive selection	3736880
7166343	7166366	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTGTGGTTCCAACAGTTGGACGG	INSR	ENSG00000171105	0.13300575991674632	[5]	[6,6]	3	hSpCas9	positive selection	3736881
7184610	7184633	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCGACCATCTGTAAGTCACACGG	INSR	ENSG00000171105	-0.031549965417592515	[4]	[5,3]	0	hSpCas9	positive selection	3736882
7184606	7184629	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.2840844661649244	[4]	[3,3]	-4	hSpCas9	positive selection	3736883
7184396	7184419	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.2117135028766902	[6]	[6,5]	5	hSpCas9	positive selection	3845485
7184322	7184345	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAATTCATCGTGTACCCGGAGGG	INSR	ENSG00000171105	-1.0170076318477625	[4]	[2,0]	-8	hSpCas9	positive selection	3845486
7172401	7172424	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAGCTAGAAGCCAACCTCGG	INSR	ENSG00000171105	0.1310923832134117	[4]	[4,3]	3	hSpCas9	positive selection	3845487
7166343	7166366	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTGTGGTTCCAACAGTTGGACGG	INSR	ENSG00000171105	0.10973471911971683	[5]	[5,4]	2	hSpCas9	positive selection	3845488
7184610	7184633	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCGACCATCTGTAAGTCACACGG	INSR	ENSG00000171105	-0.49504735648522363	[5]	[4,1]	-6	hSpCas9	positive selection	3845489
7184606	7184629	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.08912050400005084	[5]	[4,3]	-1	hSpCas9	positive selection	3845490
7172348	7172371	19	-	26780180	A375	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	1.87678933944329	[]	[]	9	hSpCas9	negative selection	3951488
7170669	7170692	19	-	26780180	A375	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.78201546976585	[]	[]	3	hSpCas9	negative selection	3951489
7184530	7184553	19	-	26780180	A375	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.371724880733839	[]	[]	0	hSpCas9	negative selection	3951490
7172309	7172332	19	+	26780180	A375	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	1.67108688467626	[]	[]	9	hSpCas9	negative selection	3951491
7170564	7170587	19	+	26780180	A375	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	1.19155974078205	[]	[]	6	hSpCas9	negative selection	3951492
7184519	7184542	19	+	26780180	A375	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.737442303447197	[]	[]	2	hSpCas9	negative selection	3951493
7172348	7172371	19	-	26780180	HT29	viability (GeCKOv2 library)	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	1.56731441647752	[]	[]	8	hSpCas9	negative selection	4059454
7170669	7170692	19	-	26780180	HT29	viability (GeCKOv2 library)	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	1.36135834800206	[]	[]	7	hSpCas9	negative selection	4059455
7184530	7184553	19	-	26780180	HT29	viability (GeCKOv2 library)	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	1.06490440291195	[]	[]	5	hSpCas9	negative selection	4059456
7172309	7172332	19	+	26780180	HT29	viability (GeCKOv2 library)	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	2.08753375129257	[]	[]	9	hSpCas9	negative selection	4059457
7170564	7170587	19	+	26780180	HT29	viability (GeCKOv2 library)	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.794044297583263	[]	[]	3	hSpCas9	negative selection	4059458
7184519	7184542	19	+	26780180	HT29	viability (GeCKOv2 library)	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	1.37037807040428	[]	[]	7	hSpCas9	negative selection	4059459
7172348	7172371	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.519515795816904	[3]	[1,1]	-8	hSpCas9	positive selection	4145004
7184530	7184553	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.006769842221266309	[5]	[3,3]	0	hSpCas9	positive selection	4145005
7172309	7172332	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.11149796201919784	[4]	[2,2]	-3	hSpCas9	positive selection	4145006
7172348	7172371	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.10148168431813331	[4]	[1,4,2,0]	-1	hSpCas9	positive selection	4209026
7184530	7184553	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	1.0112795184666739	[5]	[4,3,4,4]	7	hSpCas9	positive selection	4209027
7172309	7172332	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.7171574178133133	[4]	[1,2,2,4]	4	hSpCas9	positive selection	4209028
7184530	7184553	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.27392020092028635	[2]	[2,2]	5	hSpCas9	positive selection	4277079
7172348	7172371	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.2543346128610164	[3]	[3,1]	-5	hSpCas9	positive selection	4277080
7172309	7172332	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.39949297832616515	[3]	[3,0]	-7	hSpCas9	positive selection	4277081
7184519	7184542	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.27951564328321354	[3]	[2,3]	5	hSpCas9	positive selection	4341336
7170564	7170587	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.324978792718999	[3]	[3,3]	6	hSpCas9	positive selection	4341337
7170669	7170692	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.21670198426985693	[4]	[3,3]	4	hSpCas9	positive selection	4341338
7166201	7166223	19	+	27760321	OCIAML3	viability	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.0806044866119	[342,240]	[263,205]	0	hSpCas9	negative selection	4409966
7172348	7172370	19	-	27760321	OCIAML3	viability	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.8090954540621805	[1216,917]	[594,312]	-6	hSpCas9	negative selection	4409967
7174645	7174667	19	+	27760321	OCIAML3	viability	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.7904387727075093	[812,588]	[776,1149]	8	hSpCas9	negative selection	4409968
7267423	7267445	19	-	27760321	OCIAML3	viability	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.05927979873128547	[689,565]	[370,596]	0	hSpCas9	negative selection	4409969
7267636	7267658	19	-	27760321	OCIAML3	viability	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.0434366833437871	[484,452]	[151,211]	-7	hSpCas9	negative selection	4409970
7166201	7166223	19	+	27760321	OCIAML2	viability	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.45703921942632375	[342,240]	[242,422]	6	hSpCas9	negative selection	4493429
7172348	7172370	19	-	27760321	OCIAML2	viability	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.84421061627831	[1216,917]	[445,517]	-7	hSpCas9	negative selection	4493430
7174645	7174667	19	+	27760321	OCIAML2	viability	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.04662276241235419	[812,588]	[503,679]	0	hSpCas9	negative selection	4493431
7267423	7267445	19	-	27760321	OCIAML2	viability	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.629033026226483	[689,565]	[297,364]	-6	hSpCas9	negative selection	4493432
7267636	7267658	19	-	27760321	OCIAML2	viability	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-0.7346095404676716	[484,452]	[209,251]	-6	hSpCas9	negative selection	4493433
7166201	7166223	19	+	27760321	MV411	viability	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.1690766983536332	[342,240]	[280,113]	1	hSpCas9	negative selection	4576892
7172348	7172370	19	-	27760321	MV411	viability	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.7065481162276532	[1216,917]	[340,558]	-5	hSpCas9	negative selection	4576893
7174645	7174667	19	+	27760321	MV411	viability	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	-0.21463550929672687	[812,588]	[303,530]	-1	hSpCas9	negative selection	4576894
7267423	7267445	19	-	27760321	MV411	viability	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	0.4901669313655581	[689,565]	[685,418]	3	hSpCas9	negative selection	4576895
7267636	7267658	19	-	27760321	MV411	viability	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-2.0002694198305586	[484,452]	[72,83]	-8	hSpCas9	negative selection	4576896
7166201	7166223	19	+	27760321	HL60	viability	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.40123315748370025	[342,240]	[328,292]	5	hSpCas9	negative selection	4660355
7172348	7172370	19	-	27760321	HL60	viability	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-1.0207985528679417	[1216,917]	[284,575]	-7	hSpCas9	negative selection	4660356
7174645	7174667	19	+	27760321	HL60	viability	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.20069523862515282	[812,588]	[572,734]	2	hSpCas9	negative selection	4660357
7267423	7267445	19	-	27760321	HL60	viability	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	0.3330586301968046	[689,565]	[662,621]	4	hSpCas9	negative selection	4660358
7267636	7267658	19	-	27760321	HL60	viability	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-0.21442048989579598	[484,452]	[358,299]	-2	hSpCas9	negative selection	4660359
7166201	7166223	19	+	27760321	HT1080	viability	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.1840274778304578	[240,187]	[66,129]	0	hSpCas9	negative selection	4743818
7172348	7172370	19	-	27760321	HT1080	viability	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.8235427647378382	[917,716]	[499,659]	4	hSpCas9	negative selection	4743819
7174645	7174667	19	+	27760321	HT1080	viability	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.8146478264448644	[588,459]	[367,366]	4	hSpCas9	negative selection	4743820
7267423	7267445	19	-	27760321	HT1080	viability	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	0.7163806987146191	[565,441]	[232,435]	4	hSpCas9	negative selection	4743821
7267636	7267658	19	-	27760321	HT1080	viability	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-0.021857868895382493	[452,353]	[38,288]	0	hSpCas9	negative selection	4743822
7166201	7166223	19	+	27760321	HT29	viability after 7 days	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.06689836567540386	[240,187]	[307,274,285]	1	hSpCas9	negative selection	4827281
7172348	7172370	19	-	27760321	HT29	viability after 7 days	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.16981955280907468	[917,716]	[910,841,1041]	-2	hSpCas9	negative selection	4827282
7174645	7174667	19	+	27760321	HT29	viability after 7 days	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	-0.01061468693148171	[588,459]	[960,420,666]	0	hSpCas9	negative selection	4827283
7267423	7267445	19	-	27760321	HT29	viability after 7 days	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.2563620435019821	[565,441]	[495,576,546]	-4	hSpCas9	negative selection	4827284
7267636	7267658	19	-	27760321	HT29	viability after 7 days	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-0.9091668774325483	[452,353]	[371,318,154]	-8	hSpCas9	negative selection	4827285
7166201	7166223	19	+	27760321	HT29	viability after 25 days	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.6459739584476807	[240,187]	[104,167,204]	-5	hSpCas9	negative selection	4910744
7172348	7172370	19	-	27760321	HT29	viability after 25 days	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.08795213673895197	[917,716]	[718,1020,908]	-1	hSpCas9	negative selection	4910745
7174645	7174667	19	+	27760321	HT29	viability after 25 days	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.02933438111699127	[588,459]	[704,437,693]	0	hSpCas9	negative selection	4910746
7267423	7267445	19	-	27760321	HT29	viability after 25 days	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.4487286394249655	[565,441]	[445,472,335]	-4	hSpCas9	negative selection	4910747
7267636	7267658	19	-	27760321	HT29	viability after 25 days	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.0872156253865422	[452,353]	[218,194,238]	-7	hSpCas9	negative selection	4910748
7166201	7166223	19	+	27760321	HT29	viability after 22 days	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.23456336998058802	[240,187]	[86,400,146]	-2	hSpCas9	negative selection	4994207
7172348	7172370	19	-	27760321	HT29	viability after 22 days	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.017019337340187013	[917,716]	[912,1124,762]	0	hSpCas9	negative selection	4994208
7174645	7174667	19	+	27760321	HT29	viability after 22 days	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	-0.47298898131290495	[588,459]	[517,291,498]	-4	hSpCas9	negative selection	4994209
7267423	7267445	19	-	27760321	HT29	viability after 22 days	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.3503190170721229	[565,441]	[397,489,484]	-3	hSpCas9	negative selection	4994210
7267636	7267658	19	-	27760321	HT29	viability after 22 days	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.1059094136715724	[452,353]	[335,197,111]	-7	hSpCas9	negative selection	4994211
7166201	7166223	19	+	27760321	HT29	viability after 19 days	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-0.050728047257687536	[240,187]	[268,295,151]	0	hSpCas9	negative selection	5077670
7172348	7172370	19	-	27760321	HT29	viability after 19 days	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.1531930094164351	[917,716]	[765,1233,1087]	1	hSpCas9	negative selection	5077671
7174645	7174667	19	+	27760321	HT29	viability after 19 days	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	-0.009518920211310289	[588,459]	[845,355,610]	0	hSpCas9	negative selection	5077672
7267423	7267445	19	-	27760321	HT29	viability after 19 days	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.6053708208852536	[565,441]	[367,514,256]	-5	hSpCas9	negative selection	5077673
7267636	7267658	19	-	27760321	HT29	viability after 19 days	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.6246883479523806	[452,353]	[289,115,60]	-7	hSpCas9	negative selection	5077674
7166201	7166223	19	+	27760321	HT29	viability after 16 days	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-1.2051991992547828	[240,187]	[95,159,53]	-7	hSpCas9	negative selection	5161133
7172348	7172370	19	-	27760321	HT29	viability after 16 days	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.04366977992403176	[917,716]	[984,948,897]	0	hSpCas9	negative selection	5161134
7174645	7174667	19	+	27760321	HT29	viability after 16 days	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.08541660387474792	[588,459]	[642,381,850]	0	hSpCas9	negative selection	5161135
7267423	7267445	19	-	27760321	HT29	viability after 16 days	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.049209441309741586	[565,441]	[417,616,585]	0	hSpCas9	negative selection	5161136
7267636	7267658	19	-	27760321	HT29	viability after 16 days	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.0106181672720722	[452,353]	[253,301,116]	-7	hSpCas9	negative selection	5161137
7166201	7166223	19	+	27760321	HT29	viability after 13 days	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.004639980959803669	[240,187]	[133,277,331]	0	hSpCas9	negative selection	5244596
7172348	7172370	19	-	27760321	HT29	viability after 13 days	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.0558282809660573	[917,716]	[762,1019,951]	0	hSpCas9	negative selection	5244597
7174645	7174667	19	+	27760321	HT29	viability after 13 days	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.1332383956204204	[588,459]	[779,592,630]	1	hSpCas9	negative selection	5244598
7267423	7267445	19	-	27760321	HT29	viability after 13 days	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.417322126593335	[565,441]	[432,485,396]	-5	hSpCas9	negative selection	5244599
7267636	7267658	19	-	27760321	HT29	viability after 13 days	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.4736833158537057	[452,353]	[90,163,245]	-8	hSpCas9	negative selection	5244600
7166201	7166223	19	+	27760321	HT29	viability after 10 days	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.0055349977917606985	[240,187]	[169,423,217]	0	hSpCas9	negative selection	5328059
7172348	7172370	19	-	27760321	HT29	viability after 10 days	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.38095018274589054	[917,716]	[875,893,588]	-5	hSpCas9	negative selection	5328060
7174645	7174667	19	+	27760321	HT29	viability after 10 days	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	0.04103596149352551	[588,459]	[630,787,606]	0	hSpCas9	negative selection	5328061
7267423	7267445	19	-	27760321	HT29	viability after 10 days	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	-0.09802957337684276	[565,441]	[582,674,509]	-1	hSpCas9	negative selection	5328062
7267636	7267658	19	-	27760321	HT29	viability after 10 days	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.028192212146959	[452,353]	[276,231,231]	-8	hSpCas9	negative selection	5328063
7166201	7166223	19	+	27760321	MOLM13	viability	GTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	-1.5518646742982614	[342,240]	[94,21]	-7	hSpCas9	negative selection	5411522
7172348	7172370	19	-	27760321	MOLM13	viability	ATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.9993852839881315	[1216,917]	[388,221]	-5	hSpCas9	negative selection	5411523
7174645	7174667	19	+	27760321	MOLM13	viability	GCAGACGTCACCGAGTCGATGG	INSR	ENSG00000171105	-0.0060776913807908395	[812,588]	[571,234]	0	hSpCas9	negative selection	5411524
7267423	7267445	19	-	27760321	MOLM13	viability	ATCTGTCCGGGTACCGCGAAGG	INSR	ENSG00000171105	0.2933416701718654	[689,565]	[396,461]	2	hSpCas9	negative selection	5411525
7267636	7267658	19	-	27760321	MOLM13	viability	CTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-1.3291480343056747	[484,452]	[86,120]	-6	hSpCas9	negative selection	5411526
7293896	7293919	19	+	27661255	K562	viability	GCGGGAGCGCGGGGTCTCCTCGG	INSR	ENSG00000171105	-0.3817114726510935	[323,537]	[249,271]	-7	dCas9-KRAB	negative selection	5487014
7293913	7293936	19	-	27661255	K562	viability	GCGCCGCGCGCTCTGATCCGAGG	INSR	ENSG00000171105	0.28497418332734137	[215,226]	[189,236]	8	dCas9-KRAB	negative selection	5487015
7184530	7184553	19	-	27260156	BXPC3	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.02406618953909943	[453]	[425,498,469,544]	0	hSpCas9	negative selection	5549539
7172348	7172371	19	-	27260156	BXPC3	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.061948749133290515	[790]	[773,759,761,881]	-1	hSpCas9	negative selection	5549540
7172309	7172332	19	+	27260156	BXPC3	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.01328071605782044	[837]	[877,750,954,892]	0	hSpCas9	negative selection	5549541
7184519	7184542	19	+	27260156	BXPC3	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.3016996224461233	[495]	[541,725,617,675]	6	hSpCas9	negative selection	5613796
7170564	7170587	19	+	27260156	BXPC3	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.03296054456945091	[553]	[525,521,516,720]	0	hSpCas9	negative selection	5613797
7170669	7170692	19	-	27260156	BXPC3	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.24776250979409964	[1106]	[1234,1316,1252,1744]	5	hSpCas9	negative selection	5613798
7184530	7184553	19	-	27260156	A673	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.2753812984814722	[453]	[668,651,746,564]	6	hSpCas9	negative selection	5670790
7172348	7172371	19	-	27260156	A673	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.15232246894089563	[790]	[999,1128,1026,1055]	3	hSpCas9	negative selection	5670791
7172309	7172332	19	+	27260156	A673	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.01580292968415098	[837]	[1185,924,849,1045]	0	hSpCas9	negative selection	5670792
7184519	7184542	19	+	27260156	A673	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.3189962538671869	[495]	[771,787,554,865]	7	hSpCas9	negative selection	5735047
7170564	7170587	19	+	27260156	A673	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.004893052212718213	[553]	[725,647,664,634]	0	hSpCas9	negative selection	5735048
7170669	7170692	19	-	27260156	A673	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.292827731219242	[1106]	[1923,1376,1545,1708]	7	hSpCas9	negative selection	5735049
7184530	7184553	19	-	27260156	A375	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.3284709051879293	[453]	[318,499,607,286]	-5	hSpCas9	negative selection	5792041
7172348	7172371	19	-	27260156	A375	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.42053146160689353	[790]	[853,753,622,553]	-5	hSpCas9	negative selection	5792042
7172309	7172332	19	+	27260156	A375	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.008058587169905373	[837]	[1027,1224,865,823]	0	hSpCas9	negative selection	5792043
7184519	7184542	19	+	27260156	A375	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.4161394049857033	[495]	[615,1064,715,735]	6	hSpCas9	negative selection	5856298
7170564	7170587	19	+	27260156	A375	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.43533841268183937	[553]	[744,1208,786,808]	6	hSpCas9	negative selection	5856299
7170669	7170692	19	-	27260156	A375	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.08031829736427465	[1106]	[1293,1786,1021,1411]	1	hSpCas9	negative selection	5856300
7184530	7184553	19	-	27260156	COLO741	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.17514862934397654	[453]	[617,612,723]	4	hSpCas9	negative selection	5913292
7172348	7172371	19	-	27260156	COLO741	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.07432766780005695	[790]	[987,1108,1084]	1	hSpCas9	negative selection	5913293
7172309	7172332	19	+	27260156	COLO741	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.14497459428571136	[837]	[1068,870,970]	-3	hSpCas9	negative selection	5913294
7184519	7184542	19	+	27260156	COLO741	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	-0.04869597094789217	[495]	[666,599,576]	-1	hSpCas9	negative selection	5977549
7170564	7170587	19	+	27260156	COLO741	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.016525074925724498	[553]	[675,819,606]	0	hSpCas9	negative selection	5977550
7170669	7170692	19	-	27260156	COLO741	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.2033687915683986	[1106]	[1508,1816,1551]	4	hSpCas9	negative selection	5977551
7184530	7184553	19	-	27260156	CAL120	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.5656318440808026	[453]	[1246,826,501]	8	hSpCas9	negative selection	6034543
7172348	7172371	19	-	27260156	CAL120	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.19331312867758155	[790]	[1073,772,768]	-3	hSpCas9	negative selection	6034544
7172309	7172332	19	+	27260156	CAL120	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.2790604245971694	[837]	[1079,781,750]	-4	hSpCas9	negative selection	6034545
7184519	7184542	19	+	27260156	CAL120	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.17102915849238604	[495]	[625,582,861]	2	hSpCas9	negative selection	6098800
7170564	7170587	19	+	27260156	CAL120	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.7047428563612365	[553]	[2069,668,779]	9	hSpCas9	negative selection	6098801
7170669	7170692	19	-	27260156	CAL120	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.0018374388655699736	[1106]	[1596,1469,1107]	0	hSpCas9	negative selection	6098802
7184530	7184553	19	-	27260156	CADOES1	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.2758536685730081	[453]	[456,540,562,482]	4	hSpCas9	negative selection	6155794
7172348	7172371	19	-	27260156	CADOES1	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.07678817996741705	[790]	[844,719,896,635]	1	hSpCas9	negative selection	6155795
7172309	7172332	19	+	27260156	CADOES1	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.08468824351910054	[837]	[653,763,737,785]	-1	hSpCas9	negative selection	6155796
7184519	7184542	19	+	27260156	CADOES1	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	-0.2970701221059262	[495]	[441,321,401,333]	-5	hSpCas9	negative selection	6220051
7170564	7170587	19	+	27260156	CADOES1	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.6639156503392135	[553]	[757,546,1370,579]	9	hSpCas9	negative selection	6220052
7170669	7170692	19	-	27260156	CADOES1	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.221430461017754	[1106]	[1332,1122,1067,1279]	4	hSpCas9	negative selection	6220053
7184530	7184553	19	-	27260156	EWS502	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.3735261875690983	[453]	[579,440,1124,342]	6	hSpCas9	negative selection	6277045
7172348	7172371	19	-	27260156	EWS502	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.20531711678017428	[790]	[824,665,606,799]	-4	hSpCas9	negative selection	6277046
7172309	7172332	19	+	27260156	EWS502	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.17715050249369735	[837]	[819,1080,1160,966]	3	hSpCas9	negative selection	6277047
7184519	7184542	19	+	27260156	EWS502	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.0036409163298089103	[495]	[483,504,542,582]	0	hSpCas9	negative selection	6341302
7170564	7170587	19	+	27260156	EWS502	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.3781555287071964	[553]	[681,687,780,920]	6	hSpCas9	negative selection	6341303
7170669	7170692	19	-	27260156	EWS502	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.33311205967756785	[1106]	[1266,1405,1609,1662]	6	hSpCas9	negative selection	6341304
7184530	7184553	19	-	27260156	EW8	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.37021790869164745	[453]	[277,244,336,267]	-6	hSpCas9	negative selection	6398296
7172348	7172371	19	-	27260156	EW8	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.3289613697511603	[790]	[743,450,448,431]	-6	hSpCas9	negative selection	6398297
7172309	7172332	19	+	27260156	EW8	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.031661728901068886	[837]	[664,633,642,716]	0	hSpCas9	negative selection	6398298
7184519	7184542	19	+	27260156	EW8	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	-0.028692413188509187	[495]	[524,478,318,279]	0	hSpCas9	negative selection	6462553
7170564	7170587	19	+	27260156	EW8	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.3144098622111656	[553]	[527,448,625,612]	6	hSpCas9	negative selection	6462554
7170669	7170692	19	-	27260156	EW8	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.20264489208629466	[1106]	[1367,1101,720,1025]	4	hSpCas9	negative selection	6462555
7184530	7184553	19	-	27260156	CORL105	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.34257499947836995	[453]	[764,739,748,455]	6	hSpCas9	negative selection	6519547
7172348	7172371	19	-	27260156	CORL105	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.17916990000467492	[790]	[694,820,977,797]	-3	hSpCas9	negative selection	6519548
7172309	7172332	19	+	27260156	CORL105	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.0027413083827071416	[837]	[950,1030,1149,823]	0	hSpCas9	negative selection	6519549
7184519	7184542	19	+	27260156	CORL105	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.10053897164280352	[495]	[508,636,775,587]	2	hSpCas9	negative selection	6583804
7170564	7170587	19	+	27260156	CORL105	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.021162885753998523	[553]	[511,687,672,682]	0	hSpCas9	negative selection	6583805
7170669	7170692	19	-	27260156	CORL105	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.1645121981736397	[1106]	[1543,1314,1420,1529]	3	hSpCas9	negative selection	6583806
7184530	7184553	19	-	27260156	HS294T	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.48667420400047556	[453]	[296,189,301,179]	6	hSpCas9	negative selection	6640798
7172348	7172371	19	-	27260156	HS294T	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.11690809949154968	[790]	[249,203,321,371]	-2	hSpCas9	negative selection	6640799
7172309	7172332	19	+	27260156	HS294T	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.22379581009853433	[837]	[278,228,326,274]	-3	hSpCas9	negative selection	6640800
7184519	7184542	19	+	27260156	HS294T	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	-0.26455419979342865	[495]	[109,138,172,233]	-4	hSpCas9	negative selection	6705055
7170564	7170587	19	+	27260156	HS294T	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.08686996158678648	[553]	[159,211,244,190]	-1	hSpCas9	negative selection	6705056
7170669	7170692	19	-	27260156	HS294T	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.5442259730046155	[1106]	[466,633,586,860]	7	hSpCas9	negative selection	6705057
7184530	7184553	19	-	27260156	HCC44	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.24547986343477468	[453]	[786,421,792,505]	4	hSpCas9	negative selection	6762049
7172348	7172371	19	-	27260156	HCC44	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.13544734148406568	[790]	[1312,716,1138,852]	2	hSpCas9	negative selection	6762050
7172309	7172332	19	+	27260156	HCC44	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.027345122145050804	[837]	[681,925,1426,746]	0	hSpCas9	negative selection	6762051
7184519	7184542	19	+	27260156	HCC44	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.4635012269378106	[495]	[1014,652,909,578]	7	hSpCas9	negative selection	6826306
7170564	7170587	19	+	27260156	HCC44	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.26449714460544616	[553]	[719,827,934,545]	4	hSpCas9	negative selection	6826307
7170669	7170692	19	-	27260156	HCC44	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.24225456121638023	[1106]	[1528,1173,1660,1621]	4	hSpCas9	negative selection	6826308
7184530	7184553	19	-	27260156	G402	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.25991017112219716	[453]	[634,351,1114,532]	3	hSpCas9	negative selection	6883300
7172348	7172371	19	-	27260156	G402	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.1786882229146063	[790]	[1538,898,1189,804]	2	hSpCas9	negative selection	6883301
7172309	7172332	19	+	27260156	G402	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.08814873259318878	[837]	[1203,1139,1195,835]	1	hSpCas9	negative selection	6883302
7184519	7184542	19	+	27260156	G402	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.5254591331219505	[495]	[1152,615,1055,690]	6	hSpCas9	negative selection	6947557
7170564	7170587	19	+	27260156	G402	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.5876311129827677	[553]	[1054,925,1127,953]	7	hSpCas9	negative selection	6947558
7170669	7170692	19	-	27260156	G402	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.14160615879374916	[1106]	[1479,1515,1562,1399]	1	hSpCas9	negative selection	6947559
7184530	7184553	19	-	27260156	L33	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.2593678612234492	[453]	[457,179,465,537]	5	hSpCas9	negative selection	7004551
7172348	7172371	19	-	27260156	L33	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.06722756061541324	[790]	[831,311,597,770]	1	hSpCas9	negative selection	7004552
7172309	7172332	19	+	27260156	L33	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.04199025992297323	[837]	[1047,316,501,825]	0	hSpCas9	negative selection	7004553
7184519	7184542	19	+	27260156	L33	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.1329603294814516	[495]	[536,286,268,509]	3	hSpCas9	negative selection	7068808
7170564	7170587	19	+	27260156	L33	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.1410555006491198	[553]	[470,245,334,406]	-3	hSpCas9	negative selection	7068809
7170669	7170692	19	-	27260156	L33	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.2184800873024857	[1106]	[1163,543,849,1310]	5	hSpCas9	negative selection	7068810
7184530	7184553	19	-	27260156	K562	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.12053776859127727	[453]	[264,438,676,123]	-1	hSpCas9	negative selection	7125802
7172348	7172371	19	-	27260156	K562	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.3957707056866138	[790]	[559,569,566,448]	-5	hSpCas9	negative selection	7125803
7172309	7172332	19	+	27260156	K562	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.28458895675598816	[837]	[1086,710,1032,804]	3	hSpCas9	negative selection	7125804
7184519	7184542	19	+	27260156	K562	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.6735024972884998	[495]	[521,1156,571,577]	8	hSpCas9	negative selection	7190059
7170564	7170587	19	+	27260156	K562	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.4155663222259466	[553]	[737,509,759,615]	5	hSpCas9	negative selection	7190060
7170669	7170692	19	-	27260156	K562	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.5029213984462988	[1106]	[1574,1429,1526,1083]	6	hSpCas9	negative selection	7190061
7184530	7184553	19	-	27260156	HT29	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.09435621732227359	[453]	[511,610,542,671]	1	hSpCas9	negative selection	7247053
7172348	7172371	19	-	27260156	HT29	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.16875400308341104	[790]	[915,1090,808,649]	-3	hSpCas9	negative selection	7247054
7172309	7172332	19	+	27260156	HT29	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.08485560315208607	[837]	[952,1170,1059,700]	-2	hSpCas9	negative selection	7247055
7184519	7184542	19	+	27260156	HT29	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.12763715856123847	[495]	[556,766,661,646]	2	hSpCas9	negative selection	7311310
7170564	7170587	19	+	27260156	HT29	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.01707434678021655	[553]	[723,714,695,601]	0	hSpCas9	negative selection	7311311
7170669	7170692	19	-	27260156	HT29	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.2197826381025776	[1106]	[1850,1524,1616,1313]	4	hSpCas9	negative selection	7311312
7184530	7184553	19	-	27260156	MHHES1	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.2709979085067232	[453]	[709,959,498,384]	5	hSpCas9	negative selection	7368304
7172348	7172371	19	-	27260156	MHHES1	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.04186359588693467	[790]	[955,914,1051,598]	0	hSpCas9	negative selection	7368305
7172309	7172332	19	+	27260156	MHHES1	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.09882524901486944	[837]	[1025,1204,1083,780]	1	hSpCas9	negative selection	7368306
7184519	7184542	19	+	27260156	MHHES1	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.14471685075202306	[495]	[651,851,516,491]	2	hSpCas9	negative selection	7432561
7170564	7170587	19	+	27260156	MHHES1	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.014876690200257975	[553]	[660,651,743,489]	0	hSpCas9	negative selection	7432562
7170669	7170692	19	-	27260156	MHHES1	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.23312843058439792	[1106]	[1870,1489,1331,1238]	4	hSpCas9	negative selection	7432563
7184530	7184553	19	-	27260156	MEWO	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.328183508848863	[453]	[363,312,342]	-6	hSpCas9	negative selection	7489555
7172348	7172371	19	-	27260156	MEWO	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.04716094566061879	[790]	[833,581,755]	-1	hSpCas9	negative selection	7489556
7172309	7172332	19	+	27260156	MEWO	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.06949904424934283	[837]	[912,902,668]	1	hSpCas9	negative selection	7489557
7184519	7184542	19	+	27260156	MEWO	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.14912419592935278	[495]	[465,552,514]	3	hSpCas9	negative selection	7553812
7170564	7170587	19	+	27260156	MEWO	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.2218053321463758	[553]	[611,531,670]	5	hSpCas9	negative selection	7553813
7170669	7170692	19	-	27260156	MEWO	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.14241487864088165	[1106]	[1294,1250,911]	3	hSpCas9	negative selection	7553814
7184530	7184553	19	-	27260156	LNCAPCLONEFGC	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.5422215944569815	[453]	[585,476,777,588]	8	hSpCas9	negative selection	7610806
7172348	7172371	19	-	27260156	LNCAPCLONEFGC	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.4339195653484544	[790]	[589,467,676,410]	-6	hSpCas9	negative selection	7610807
7172309	7172332	19	+	27260156	LNCAPCLONEFGC	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.3327252085969341	[837]	[674,605,622,507]	-5	hSpCas9	negative selection	7610808
7184519	7184542	19	+	27260156	LNCAPCLONEFGC	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.34095337665838976	[495]	[378,528,748,651]	5	hSpCas9	negative selection	7675063
7170564	7170587	19	+	27260156	LNCAPCLONEFGC	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.4593136788925326	[553]	[723,631,732,679]	7	hSpCas9	negative selection	7675064
7170669	7170692	19	-	27260156	LNCAPCLONEFGC	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.30685575813717314	[1106]	[1286,1184,1329,1174]	5	hSpCas9	negative selection	7675065
7184530	7184553	19	-	27260156	PANC0327	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.3182547216344197	[453]	[206,333,427,313]	-5	hSpCas9	negative selection	7732057
7172348	7172371	19	-	27260156	PANC0327	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.2042140965530097	[790]	[558,382,875,646]	-3	hSpCas9	negative selection	7732058
7172309	7172332	19	+	27260156	PANC0327	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.011775006183426084	[837]	[662,679,917,742]	0	hSpCas9	negative selection	7732059
7184519	7184542	19	+	27260156	PANC0327	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.4027616225474414	[495]	[706,449,550,648]	6	hSpCas9	negative selection	7796314
7170564	7170587	19	+	27260156	PANC0327	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.03196947055645796	[553]	[698,273,567,428]	0	hSpCas9	negative selection	7796315
7170669	7170692	19	-	27260156	PANC0327	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	-0.12749540353331712	[1106]	[868,658,966,1133]	-2	hSpCas9	negative selection	7796316
7184530	7184553	19	-	27260156	NCIH2009	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.3217778236472884	[453]	[1053,830,542]	4	hSpCas9	negative selection	7853308
7172348	7172371	19	-	27260156	NCIH2009	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.3479443887688686	[790]	[839,751,1007]	-5	hSpCas9	negative selection	7853309
7172309	7172332	19	+	27260156	NCIH2009	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.4086463379790127	[837]	[938,815,901]	-5	hSpCas9	negative selection	7853310
7184519	7184542	19	+	27260156	NCIH2009	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	-0.03769425467309201	[495]	[830,565,659]	0	hSpCas9	negative selection	7917565
7170564	7170587	19	+	27260156	NCIH2009	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.09151429306933845	[553]	[695,731,743]	-1	hSpCas9	negative selection	7917566
7170669	7170692	19	-	27260156	NCIH2009	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.4045596768652173	[1106]	[2723,1943,1605]	5	hSpCas9	negative selection	7917567
7184530	7184553	19	-	27260156	NCIH1373	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.3817376143625737	[453]	[769,684,561,169]	4	hSpCas9	negative selection	7974559
7172348	7172371	19	-	27260156	NCIH1373	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.3114630855756695	[790]	[1088,877,1320,295]	3	hSpCas9	negative selection	7974560
7172309	7172332	19	+	27260156	NCIH1373	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.09898172194978827	[837]	[1450,572,925,314]	1	hSpCas9	negative selection	7974561
7184519	7184542	19	+	27260156	NCIH1373	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.7475984022997294	[495]	[1169,607,1041,257]	7	hSpCas9	negative selection	8038816
7170564	7170587	19	+	27260156	NCIH1373	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.08787944208038787	[553]	[772,450,549,241]	0	hSpCas9	negative selection	8038817
7170669	7170692	19	-	27260156	NCIH1373	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.4711758992082944	[1106]	[2388,1199,1638,475]	4	hSpCas9	negative selection	8038818
7184530	7184553	19	-	27260156	PATU8902	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.6199358914646743	[453]	[1328,817,605,1248]	6	hSpCas9	negative selection	8095810
7172348	7172371	19	-	27260156	PATU8902	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.18754248184632005	[790]	[1005,919,827,1166]	-2	hSpCas9	negative selection	8095811
7172309	7172332	19	+	27260156	PATU8902	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.01355268613511218	[837]	[1578,992,761,1510]	0	hSpCas9	negative selection	8095812
7184519	7184542	19	+	27260156	PATU8902	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	-0.409312900017461	[495]	[471,693,299,688]	-4	hSpCas9	negative selection	8160067
7170564	7170587	19	+	27260156	PATU8902	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.5351999899941903	[553]	[816,1657,1020,981]	5	hSpCas9	negative selection	8160068
7170669	7170692	19	-	27260156	PATU8902	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.33578385473405614	[1106]	[1788,2282,1595,2226]	3	hSpCas9	negative selection	8160069
7184530	7184553	19	-	27260156	PANC1	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.1480773074735378	[453]	[485,480,454,325]	2	hSpCas9	negative selection	8217061
7172348	7172371	19	-	27260156	PANC1	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.02556991824713095	[790]	[499,885,791,549]	0	hSpCas9	negative selection	8217062
7172309	7172332	19	+	27260156	PANC1	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.06575525918169856	[837]	[629,875,916,627]	1	hSpCas9	negative selection	8217063
7184519	7184542	19	+	27260156	PANC1	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.16170146819719233	[495]	[385,639,454,455]	2	hSpCas9	negative selection	8281318
7170564	7170587	19	+	27260156	PANC1	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.12292896748025597	[553]	[479,665,592,379]	2	hSpCas9	negative selection	8281319
7170669	7170692	19	-	27260156	PANC1	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.2466869637267688	[1106]	[1183,1160,1268,920]	4	hSpCas9	negative selection	8281320
7184530	7184553	19	-	27260156	PANC0813	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.3538564742030653	[453]	[712,702,670,642]	6	hSpCas9	negative selection	8338312
7172348	7172371	19	-	27260156	PANC0813	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.055357347858676964	[790]	[1304,996,861,739]	0	hSpCas9	negative selection	8338313
7172309	7172332	19	+	27260156	PANC0813	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.041886206640536994	[837]	[1331,849,704,968]	0	hSpCas9	negative selection	8338314
7184519	7184542	19	+	27260156	PANC0813	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.5201029222009237	[495]	[797,617,1334,601]	8	hSpCas9	negative selection	8402569
7170564	7170587	19	+	27260156	PANC0813	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	-0.03912386690697264	[553]	[641,473,716,696]	0	hSpCas9	negative selection	8402570
7170669	7170692	19	-	27260156	PANC0813	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.4111680895545555	[1106]	[1996,1641,1883,1432]	6	hSpCas9	negative selection	8402571
7184530	7184553	19	-	27260156	RDES	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.2702788829662408	[453]	[517,587,651,795]	4	hSpCas9	negative selection	8459563
7172348	7172371	19	-	27260156	RDES	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.08338378067601881	[790]	[761,714,946,1050]	-1	hSpCas9	negative selection	8459564
7172309	7172332	19	+	27260156	RDES	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.1875509879640722	[837]	[708,838,872,990]	-3	hSpCas9	negative selection	8459565
7184519	7184542	19	+	27260156	RDES	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.24060219620057727	[495]	[516,721,665,821]	4	hSpCas9	negative selection	8523820
7170564	7170587	19	+	27260156	RDES	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.23064308041863654	[553]	[633,667,798,927]	4	hSpCas9	negative selection	8523821
7170669	7170692	19	-	27260156	RDES	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.23476858509976362	[1106]	[1284,1478,1443,1833]	4	hSpCas9	negative selection	8523822
7184530	7184553	19	-	27260156	PC3	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.08043793654342563	[453]	[386,510,813,303]	1	hSpCas9	negative selection	8580814
7172348	7172371	19	-	27260156	PC3	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.6015922803543656	[790]	[269,660,729,557]	-8	hSpCas9	negative selection	8580815
7172309	7172332	19	+	27260156	PC3	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.192406172360169	[837]	[757,691,1015,1380]	4	hSpCas9	negative selection	8580816
7184519	7184542	19	+	27260156	PC3	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.1994485856088083	[495]	[488,490,831,524]	4	hSpCas9	negative selection	8645071
7170564	7170587	19	+	27260156	PC3	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.2065589280078761	[553]	[363,685,1158,600]	4	hSpCas9	negative selection	8645072
7170669	7170692	19	-	27260156	PC3	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.12881202288174776	[1106]	[830,942,2494,1108]	3	hSpCas9	negative selection	8645073
7184530	7184553	19	-	27260156	PATU8988T	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.08862324376056357	[453]	[388,386,371,507]	-1	hSpCas9	negative selection	8702065
7172348	7172371	19	-	27260156	PATU8988T	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.4018198259724581	[790]	[475,695,457,706]	-6	hSpCas9	negative selection	8702066
7172309	7172332	19	+	27260156	PATU8988T	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.06796955411202732	[837]	[806,688,901,992]	1	hSpCas9	negative selection	8702067
7184519	7184542	19	+	27260156	PATU8988T	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.022292513662187083	[495]	[494,475,398,584]	0	hSpCas9	negative selection	8766322
7170564	7170587	19	+	27260156	PATU8988T	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.15747082825778067	[553]	[649,563,499,678]	2	hSpCas9	negative selection	8766323
7170669	7170692	19	-	27260156	PATU8988T	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.001915394272222315	[1106]	[1304,1457,772,763]	0	hSpCas9	negative selection	8766324
7184530	7184553	19	-	27260156	T47D	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.22825215112161676	[453]	[663,586,614,614]	5	hSpCas9	negative selection	8823316
7172348	7172371	19	-	27260156	T47D	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.2508373669534584	[790]	[913,633,789,771]	-5	hSpCas9	negative selection	8823317
7172309	7172332	19	+	27260156	T47D	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.009910906692814025	[837]	[983,909,905,1087]	0	hSpCas9	negative selection	8823318
7184519	7184542	19	+	27260156	T47D	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.2858682480369229	[495]	[706,756,664,683]	6	hSpCas9	negative selection	8887573
7170564	7170587	19	+	27260156	T47D	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.20648311794794097	[553]	[700,731,772,773]	4	hSpCas9	negative selection	8887574
7170669	7170692	19	-	27260156	T47D	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.16542348410801733	[1106]	[1398,1395,1594,1394]	3	hSpCas9	negative selection	8887575
7184530	7184553	19	-	27260156	SU8686	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.21802570932801105	[453]	[439,406,553,751]	3	hSpCas9	negative selection	8944567
7172348	7172371	19	-	27260156	SU8686	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.3045481768582255	[790]	[627,560,649,720]	-5	hSpCas9	negative selection	8944568
7172309	7172332	19	+	27260156	SU8686	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.3058024601089646	[837]	[604,642,577,903]	-5	hSpCas9	negative selection	8944569
7184519	7184542	19	+	27260156	SU8686	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.15482174618629796	[495]	[417,452,651,720]	2	hSpCas9	negative selection	9008824
7170564	7170587	19	+	27260156	SU8686	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.12237839577489343	[553]	[531,496,673,727]	2	hSpCas9	negative selection	9008825
7170669	7170692	19	-	27260156	SU8686	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.28590175514125526	[1106]	[1262,1470,1340,1242]	5	hSpCas9	negative selection	9008826
7184530	7184553	19	-	27260156	SKES1	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.26492745950599067	[453]	[644,626,442,487]	5	hSpCas9	negative selection	9065818
7172348	7172371	19	-	27260156	SKES1	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.08699684883321934	[790]	[997,560,769,657]	-2	hSpCas9	negative selection	9065819
7172309	7172332	19	+	27260156	SKES1	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	-0.1506082936098111	[837]	[965,763,681,637]	-3	hSpCas9	negative selection	9065820
7184519	7184542	19	+	27260156	SKES1	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.29360247738969447	[495]	[529,851,541,524]	6	hSpCas9	negative selection	9130075
7170564	7170587	19	+	27260156	SKES1	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.21484966708871858	[553]	[705,747,595,542]	4	hSpCas9	negative selection	9130076
7170669	7170692	19	-	27260156	SKES1	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.16406741727852614	[1106]	[1695,1160,1057,1094]	3	hSpCas9	negative selection	9130077
7184530	7184553	19	-	27260156	TOV112D	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	-0.22231423537537884	[453]	[406,750,217,275]	-4	hSpCas9	negative selection	9187069
7172348	7172371	19	-	27260156	TOV112D	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.21281605475294707	[790]	[705,749,669,626]	-4	hSpCas9	negative selection	9187070
7172309	7172332	19	+	27260156	TOV112D	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.19386973230546423	[837]	[1040,1076,720,1032]	4	hSpCas9	negative selection	9187071
7184519	7184542	19	+	27260156	TOV112D	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.27150209680831616	[495]	[542,872,587,459]	5	hSpCas9	negative selection	9251326
7170564	7170587	19	+	27260156	TOV112D	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.05441726131969374	[553]	[620,462,774,424]	1	hSpCas9	negative selection	9251327
7170669	7170692	19	-	27260156	TOV112D	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.2443782119783786	[1106]	[1450,1554,1026,1289]	5	hSpCas9	negative selection	9251328
7184530	7184553	19	-	27260156	TC71	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.14364515305575423	[453]	[471,550,441,699]	3	hSpCas9	negative selection	9308320
7172348	7172371	19	-	27260156	TC71	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	0.00955750099571162	[790]	[688,879,873,981]	0	hSpCas9	negative selection	9308321
7172309	7172332	19	+	27260156	TC71	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.022064296109218895	[837]	[946,781,850,1079]	0	hSpCas9	negative selection	9308322
7184519	7184542	19	+	27260156	TC71	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.09459122897292309	[495]	[507,472,749,532]	2	hSpCas9	negative selection	9372577
7170564	7170587	19	+	27260156	TC71	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.024133723891288622	[553]	[558,657,572,628]	0	hSpCas9	negative selection	9372578
7170669	7170692	19	-	27260156	TC71	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.10323191847300217	[1106]	[1343,1224,1170,1365]	2	hSpCas9	negative selection	9372579
7184530	7184553	19	-	27260156	TC32	viability	CGACGACCCCACCAAGTGCGTGG	INSR	ENSG00000171105	0.5076952131150857	[453]	[562,388,930,655]	8	hSpCas9	negative selection	9429571
7172348	7172371	19	-	27260156	TC32	viability	AATCCGCCGATCCTACGCTCTGG	INSR	ENSG00000171105	-0.07989973799646333	[790]	[746,494,818,808]	-1	hSpCas9	negative selection	9429572
7172309	7172332	19	+	27260156	TC32	viability	CTCGAATCAGACGTAACTTCCGG	INSR	ENSG00000171105	0.04925960937972684	[837]	[675,648,1123,900]	0	hSpCas9	negative selection	9429573
7184519	7184542	19	+	27260156	TC32	viability	GTTGCGGCAGGCCACGCACTTGG	INSR	ENSG00000171105	0.07507488424807908	[495]	[438,391,736,450]	1	hSpCas9	negative selection	9493828
7170564	7170587	19	+	27260156	TC32	viability	GGGCAATGTCGTTTCTCTCCTGG	INSR	ENSG00000171105	0.3477272103814345	[553]	[557,586,817,717]	6	hSpCas9	negative selection	9493829
7170669	7170692	19	-	27260156	TC32	viability	ACACAACCTCACCATCACTCAGG	INSR	ENSG00000171105	0.3324726959909643	[1106]	[1072,1136,1571,1530]	6	hSpCas9	negative selection	9493830
7166200	7166223	19	+	27869803	HPAFII	viability after 27 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	1.1231385648219494	[252]	[424,176,NaN]	8	hSpCas9	negative selection	9570588
7167995	7168018	19	+	27869803	HPAFII	viability after 27 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	1.26070675586793	[55]	[93,50,NaN]	8	hSpCas9	negative selection	9570589
7172316	7172339	19	+	27869803	HPAFII	viability after 27 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.45087084430657054	[419]	[489,144,NaN]	3	hSpCas9	negative selection	9570590
7174611	7174634	19	-	27869803	HPAFII	viability after 27 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.42719920755914176	[66]	[60,35,NaN]	3	hSpCas9	negative selection	9570591
7184396	7184419	19	-	27869803	HPAFII	viability after 27 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.24831189857854108	[456]	[150,244,NaN]	-2	hSpCas9	negative selection	9570592
7267572	7267595	19	-	27869803	HPAFII	viability after 27 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.1721530707653003	[652]	[376,394,NaN]	1	hSpCas9	negative selection	9570594
7166200	7166223	19	+	27869803	HPAFII	viability after 15 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.8333744750245482	[252]	[621,398,NaN]	8	hSpCas9	negative selection	9653037
7167995	7168018	19	+	27869803	HPAFII	viability after 15 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	1.0552093652592232	[55]	[285,24,NaN]	9	hSpCas9	negative selection	9653038
7172316	7172339	19	+	27869803	HPAFII	viability after 15 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.2816112258460406	[419]	[901,328,NaN]	3	hSpCas9	negative selection	9653039
7174611	7174634	19	-	27869803	HPAFII	viability after 15 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.17925878702660913	[66]	[83,79,NaN]	2	hSpCas9	negative selection	9653040
7184396	7184419	19	-	27869803	HPAFII	viability after 15 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.08801631384662278	[456]	[458,463,NaN]	-1	hSpCas9	negative selection	9653041
7267572	7267595	19	-	27869803	HPAFII	viability after 15 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.2025975222697618	[652]	[888,756,NaN]	2	hSpCas9	negative selection	9653043
7166200	7166223	19	+	27869803	ASPC1	viability after 36 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.32511310181614106	[836]	[469,519,166]	3	hSpCas9	negative selection	9735486
7167995	7168018	19	+	27869803	ASPC1	viability after 36 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-0.07581582799209241	[179]	[82,111,0]	-1	hSpCas9	negative selection	9735487
7172316	7172339	19	+	27869803	ASPC1	viability after 36 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.038549704291103604	[1142]	[263,440,482]	0	hSpCas9	negative selection	9735488
7174611	7174634	19	-	27869803	ASPC1	viability after 36 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	0.004346918665445232	[278]	[121,105,72]	0	hSpCas9	negative selection	9735489
7184396	7184419	19	-	27869803	ASPC1	viability after 36 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.30602989536912073	[1180]	[568,385,122]	-3	hSpCas9	negative selection	9735490
7267572	7267595	19	-	27869803	ASPC1	viability after 36 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.017913748715425504	[1429]	[512,260,657]	0	hSpCas9	negative selection	9735492
7166200	7166223	19	+	27869803	PATU8988S	viability after 35 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	1.0618576507756807	[762]	[431,851,NaN]	9	hSpCas9	negative selection	9817935
7167995	7168018	19	+	27869803	PATU8988S	viability after 35 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	-0.2228284148406683	[148]	[16,85,NaN]	-2	hSpCas9	negative selection	9817936
7172316	7172339	19	+	27869803	PATU8988S	viability after 35 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.7550951393175669	[1114]	[298,232,NaN]	-6	hSpCas9	negative selection	9817937
7174611	7174634	19	-	27869803	PATU8988S	viability after 35 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.1589345308320277	[326]	[100,134,NaN]	-2	hSpCas9	negative selection	9817938
7184396	7184419	19	-	27869803	PATU8988S	viability after 35 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.735428321142168	[880]	[265,159,NaN]	-6	hSpCas9	negative selection	9817939
7267572	7267595	19	-	27869803	PATU8988S	viability after 35 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.40768617663041296	[1229]	[344,401,NaN]	-4	hSpCas9	negative selection	9817941
7166200	7166223	19	+	27869803	PATU8988S	viability after 31 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	0.8336382085498802	[762]	[400,721,NaN]	8	hSpCas9	negative selection	9900384
7167995	7168018	19	+	27869803	PATU8988S	viability after 31 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	0.31679624428171715	[148]	[84,59,NaN]	4	hSpCas9	negative selection	9900385
7172316	7172339	19	+	27869803	PATU8988S	viability after 31 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	-0.6805415431855533	[1114]	[272,282,NaN]	-6	hSpCas9	negative selection	9900386
7174611	7174634	19	-	27869803	PATU8988S	viability after 31 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.35888017192245025	[326]	[69,141,NaN]	-4	hSpCas9	negative selection	9900387
7184396	7184419	19	-	27869803	PATU8988S	viability after 31 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.32581162890386167	[880]	[274,286,NaN]	-4	hSpCas9	negative selection	9900388
7267572	7267595	19	-	27869803	PATU8988S	viability after 31 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.33684051855574626	[1229]	[236,580,NaN]	-4	hSpCas9	negative selection	9900390
7166200	7166223	19	+	27869803	HPAFII	viability after 35 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	1.6485286776476316	[252]	[441,355,NaN]	9	hSpCas9	negative selection	9982833
7167995	7168018	19	+	27869803	HPAFII	viability after 35 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	1.1696460136190654	[55]	[83,40,NaN]	7	hSpCas9	negative selection	9982834
7172316	7172339	19	+	27869803	HPAFII	viability after 35 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.2865435266361769	[419]	[351,154,NaN]	1	hSpCas9	negative selection	9982835
7174611	7174634	19	-	27869803	HPAFII	viability after 35 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-1.3071060289335728	[66]	[16,9,NaN]	-6	hSpCas9	negative selection	9982836
7184396	7184419	19	-	27869803	HPAFII	viability after 35 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.06041742090895119	[456]	[149,343,NaN]	0	hSpCas9	negative selection	9982837
7267572	7267595	19	-	27869803	HPAFII	viability after 35 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.15163994719453355	[652]	[211,541,NaN]	0	hSpCas9	negative selection	9982839
7166200	7166223	19	+	27869803	HPAFII	viability after 31 days	GGTCCGGCGTTCATCCGAAAAGG	INSR	ENSG00000171105	1.5617250293689093	[252]	[444,390,NaN]	9	hSpCas9	negative selection	10065282
7167995	7168018	19	+	27869803	HPAFII	viability after 31 days	AAGAGGTCTCGGAAGTCGGGGGG	INSR	ENSG00000171105	0.9105793134040341	[55]	[71,44,NaN]	6	hSpCas9	negative selection	10065283
7172316	7172339	19	+	27869803	HPAFII	viability after 31 days	CAGACGTAACTTCCGGAAGAAGG	INSR	ENSG00000171105	0.5255433018327493	[419]	[412,258,NaN]	4	hSpCas9	negative selection	10065284
7174611	7174634	19	-	27869803	HPAFII	viability after 31 days	GAGGATGCACCGTCATCAACGGG	INSR	ENSG00000171105	-0.29692151872761907	[66]	[32,27,NaN]	-2	hSpCas9	negative selection	10065285
7184396	7184419	19	-	27869803	HPAFII	viability after 31 days	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.07969131742486046	[456]	[179,310,NaN]	0	hSpCas9	negative selection	10065286
7267572	7267595	19	-	27869803	HPAFII	viability after 31 days	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.21745607483636675	[652]	[349,508,NaN]	1	hSpCas9	negative selection	10065288
7184321	7184344	19	+	28162770	P31FUJ	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	-0.44322198408475044	[139]	[120]	-4	hSpCas9	negative selection	10175130
7170658	7170681	19	+	28162770	P31FUJ	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.01577296784502369	[307]	[357]	0	hSpCas9	negative selection	10175131
7166306	7166329	19	+	28162770	P31FUJ	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.015125309029206946	[79]	[94]	0	hSpCas9	negative selection	10175132
7293792	7293815	19	-	28162770	P31FUJ	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-0.2807366814780804	[152]	[147]	-3	hSpCas9	negative selection	10175133
7267636	7267659	19	-	28162770	P31FUJ	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.3173948781461011	[111]	[163]	3	hSpCas9	negative selection	10175134
7267572	7267595	19	-	28162770	P31FUJ	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.34412297724135904	[239]	[357]	4	hSpCas9	negative selection	10175135
7267382	7267405	19	+	28162770	P31FUJ	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	1.054666419729611	[321]	[785]	9	hSpCas9	negative selection	10175136
7184606	7184629	19	+	28162770	P31FUJ	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.09377225532934896	[495]	[621]	0	hSpCas9	negative selection	10175137
7184396	7184419	19	-	28162770	P31FUJ	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.43056625298178813	[241]	[210]	-4	hSpCas9	negative selection	10175138
7172337	7172360	19	+	28162770	P31FUJ	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	0.017977049512773124	[531]	[632]	0	hSpCas9	negative selection	10175139
7184321	7184344	19	+	28162770	TF1	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	NaN	[NaN]	[61]	1	hSpCas9	negative selection	10344496
7170658	7170681	19	+	28162770	TF1	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	NaN	[NaN]	[288]	1	hSpCas9	negative selection	10344497
7166306	7166329	19	+	28162770	TF1	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10344498
7293792	7293815	19	-	28162770	TF1	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10344499
7267636	7267659	19	-	28162770	TF1	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10344500
7267572	7267595	19	-	28162770	TF1	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	NaN	[NaN]	[120]	1	hSpCas9	negative selection	10344501
7267382	7267405	19	+	28162770	TF1	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	NaN	[NaN]	[431]	1	hSpCas9	negative selection	10344502
7184606	7184629	19	+	28162770	TF1	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	NaN	[NaN]	[252]	1	hSpCas9	negative selection	10344503
7184396	7184419	19	-	28162770	TF1	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	NaN	[NaN]	[111]	1	hSpCas9	negative selection	10344504
7172337	7172360	19	+	28162770	TF1	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	NaN	[NaN]	[305]	1	hSpCas9	negative selection	10344505
7184321	7184344	19	+	28162770	SKM1	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	-1.59067615191555	[45]	[26]	-8	hSpCas9	negative selection	10513862
7170658	7170681	19	+	28162770	SKM1	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.3674358345565242	[53]	[73]	-3	hSpCas9	negative selection	10513863
7166306	7166329	19	+	28162770	SKM1	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.9919266994643179	[17]	[15]	-6	hSpCas9	negative selection	10513864
7293792	7293815	19	-	28162770	SKM1	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-1.6134150762105879	[44]	[25]	-8	hSpCas9	negative selection	10513865
7267636	7267659	19	-	28162770	SKM1	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.7495402869368291	[35]	[106]	7	hSpCas9	negative selection	10513866
7267572	7267595	19	-	28162770	SKM1	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-1.1268562795504264	[62]	[50]	-7	hSpCas9	negative selection	10513867
7267382	7267405	19	+	28162770	SKM1	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.38835816781954513	[85]	[198]	4	hSpCas9	negative selection	10513868
7184606	7184629	19	+	28162770	SKM1	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-1.7606011533578623	[114]	[59]	-8	hSpCas9	negative selection	10513869
7184396	7184419	19	-	28162770	SKM1	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-2.5996092766855576	[47]	[13]	-9	hSpCas9	negative selection	10513870
7172337	7172360	19	+	28162770	SKM1	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-2.069929211465591	[113]	[47]	-8	hSpCas9	negative selection	10513871
7184321	7184344	19	+	28162770	SKM1	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	-1.59067615191555	[45]	[26]	-8	hSpCas9	negative selection	10683228
7170658	7170681	19	+	28162770	SKM1	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.3674358345565242	[53]	[73]	-3	hSpCas9	negative selection	10683229
7166306	7166329	19	+	28162770	SKM1	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.9919266994643179	[17]	[15]	-6	hSpCas9	negative selection	10683230
7293792	7293815	19	-	28162770	SKM1	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-1.6134150762105879	[44]	[25]	-8	hSpCas9	negative selection	10683231
7267636	7267659	19	-	28162770	SKM1	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.7495402869368291	[35]	[106]	7	hSpCas9	negative selection	10683232
7267572	7267595	19	-	28162770	SKM1	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-1.1268562795504264	[62]	[50]	-7	hSpCas9	negative selection	10683233
7267382	7267405	19	+	28162770	SKM1	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.38835816781954513	[85]	[198]	4	hSpCas9	negative selection	10683234
7184606	7184629	19	+	28162770	SKM1	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-1.7606011533578623	[114]	[59]	-8	hSpCas9	negative selection	10683235
7184396	7184419	19	-	28162770	SKM1	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-2.5996092766855576	[47]	[13]	-9	hSpCas9	negative selection	10683236
7172337	7172360	19	+	28162770	SKM1	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-2.069929211465591	[113]	[47]	-8	hSpCas9	negative selection	10683237
7184321	7184344	19	+	28162770	PL21	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	-0.3043329683714684	[121]	[42]	-2	hSpCas9	negative selection	10852594
7170658	7170681	19	+	28162770	PL21	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.2901860120937607	[235]	[83]	-2	hSpCas9	negative selection	10852595
7166306	7166329	19	+	28162770	PL21	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.022252806847127937	[83]	[35]	0	hSpCas9	negative selection	10852596
7293792	7293815	19	-	28162770	PL21	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-0.819225710377611	[149]	[36]	-5	hSpCas9	negative selection	10852597
7267636	7267659	19	-	28162770	PL21	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-0.8557136202441973	[157]	[37]	-5	hSpCas9	negative selection	10852598
7267572	7267595	19	-	28162770	PL21	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-1.4262995222079955	[246]	[39]	-7	hSpCas9	negative selection	10852599
7267382	7267405	19	+	28162770	PL21	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	-0.23778177546286233	[232]	[85]	-2	hSpCas9	negative selection	10852600
7184606	7184629	19	+	28162770	PL21	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.14016700971289675	[394]	[155]	-1	hSpCas9	negative selection	10852601
7184396	7184419	19	-	28162770	PL21	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-1.6623568617607447	[159]	[21]	-8	hSpCas9	negative selection	10852602
7172337	7172360	19	+	28162770	PL21	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-0.6324659846836894	[316]	[88]	-4	hSpCas9	negative selection	10852603
7184321	7184344	19	+	28162770	P31FUJ	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	-0.44322198408475044	[139]	[120]	-4	hSpCas9	negative selection	11021960
7170658	7170681	19	+	28162770	P31FUJ	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.01577296784502369	[307]	[357]	0	hSpCas9	negative selection	11021961
7166306	7166329	19	+	28162770	P31FUJ	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.015125309029206946	[79]	[94]	0	hSpCas9	negative selection	11021962
7293792	7293815	19	-	28162770	P31FUJ	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-0.2807366814780804	[152]	[147]	-3	hSpCas9	negative selection	11021963
7267636	7267659	19	-	28162770	P31FUJ	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.3173948781461011	[111]	[163]	3	hSpCas9	negative selection	11021964
7267572	7267595	19	-	28162770	P31FUJ	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.34412297724135904	[239]	[357]	4	hSpCas9	negative selection	11021965
7267382	7267405	19	+	28162770	P31FUJ	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	1.054666419729611	[321]	[785]	9	hSpCas9	negative selection	11021966
7184606	7184629	19	+	28162770	P31FUJ	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.09377225532934896	[495]	[621]	0	hSpCas9	negative selection	11021967
7184396	7184419	19	-	28162770	P31FUJ	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.43056625298178813	[241]	[210]	-4	hSpCas9	negative selection	11021968
7172337	7172360	19	+	28162770	P31FUJ	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	0.017977049512773124	[531]	[632]	0	hSpCas9	negative selection	11021969
7184321	7184344	19	+	28162770	OCIAML5	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.5753546528706792	[57]	[155]	5	hSpCas9	negative selection	11191326
7170658	7170681	19	+	28162770	OCIAML5	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-1.7868205462485587	[280]	[146]	-7	hSpCas9	negative selection	11191327
7166306	7166329	19	+	28162770	OCIAML5	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.7671776732774835	[32]	[34]	-5	hSpCas9	negative selection	11191328
7293792	7293815	19	-	28162770	OCIAML5	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-0.17690626117126274	[61]	[98]	-1	hSpCas9	negative selection	11191329
7267636	7267659	19	-	28162770	OCIAML5	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-0.45245911215475926	[93]	[123]	-3	hSpCas9	negative selection	11191330
7267572	7267595	19	-	28162770	OCIAML5	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.15459715941701385	[107]	[216]	1	hSpCas9	negative selection	11191331
7267382	7267405	19	+	28162770	OCIAML5	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	1.018946988415925	[151]	[555]	8	hSpCas9	negative selection	11191332
7184606	7184629	19	+	28162770	OCIAML5	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.5138103060726344	[245]	[310]	-4	hSpCas9	negative selection	11191333
7184396	7184419	19	-	28162770	OCIAML5	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.8993722856423536	[92]	[89]	-5	hSpCas9	negative selection	11191334
7172337	7172360	19	+	28162770	OCIAML5	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-1.138370756020638	[249]	[204]	-6	hSpCas9	negative selection	11191335
7184321	7184344	19	+	28162770	EOL1	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.738396455713639	[189]	[166]	6	hSpCas9	negative selection	11360692
7170658	7170681	19	+	28162770	EOL1	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.3169304908968117	[278]	[117]	-2	hSpCas9	negative selection	11360693
7166306	7166329	19	+	28162770	EOL1	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.5018566997482554	[125]	[93]	4	hSpCas9	negative selection	11360694
7293792	7293815	19	-	28162770	EOL1	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.5172459210712959	[247]	[186]	5	hSpCas9	negative selection	11360695
7267636	7267659	19	-	28162770	EOL1	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.17812184815526208	[254]	[151]	1	hSpCas9	negative selection	11360696
7267572	7267595	19	-	28162770	EOL1	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.7736253395986126	[476]	[146]	-5	hSpCas9	negative selection	11360697
7267382	7267405	19	+	28162770	EOL1	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	-0.20403643449087844	[386]	[176]	-1	hSpCas9	negative selection	11360698
7184606	7184629	19	+	28162770	EOL1	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.028607364969797988	[605]	[312]	0	hSpCas9	negative selection	11360699
7184396	7184419	19	-	28162770	EOL1	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.9083422425942073	[170]	[47]	-6	hSpCas9	negative selection	11360700
7172337	7172360	19	+	28162770	EOL1	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	1.2114289193586962	[399]	[487]	8	hSpCas9	negative selection	11360701
7184321	7184344	19	+	28162770	MOLM13	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	-1.2063404572736647	[149]	[46]	-6	hSpCas9	negative selection	11530058
7170658	7170681	19	+	28162770	MOLM13	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-1.3819702690275608	[309]	[85]	-6	hSpCas9	negative selection	11530059
7166306	7166329	19	+	28162770	MOLM13	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.052851882265734895	[71]	[53]	0	hSpCas9	negative selection	11530060
7293792	7293815	19	-	28162770	MOLM13	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.22124941396145367	[209]	[176]	1	hSpCas9	negative selection	11530061
7267636	7267659	19	-	28162770	MOLM13	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.9890552316847658	[261]	[375]	7	hSpCas9	negative selection	11530062
7267572	7267595	19	-	28162770	MOLM13	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.008964125336020548	[301]	[216]	0	hSpCas9	negative selection	11530063
7267382	7267405	19	+	28162770	MOLM13	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.4769345211475859	[317]	[319]	3	hSpCas9	negative selection	11530064
7184606	7184629	19	+	28162770	MOLM13	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.28565495411195585	[670]	[397]	-2	hSpCas9	negative selection	11530065
7184396	7184419	19	-	28162770	MOLM13	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-3.210182523568059	[255]	[19]	-8	hSpCas9	negative selection	11530066
7172337	7172360	19	+	28162770	MOLM13	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-0.446380744429537	[489]	[259]	-3	hSpCas9	negative selection	11530067
7184321	7184344	19	+	28162770	HEL	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.5751755481877223	[152]	[145]	5	hSpCas9	negative selection	11699424
7170658	7170681	19	+	28162770	HEL	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.8301970509866878	[321]	[115]	-5	hSpCas9	negative selection	11699425
7166306	7166329	19	+	28162770	HEL	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.3376323612507106	[72]	[36]	-2	hSpCas9	negative selection	11699426
7293792	7293815	19	-	28162770	HEL	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.04039425305096439	[166]	[109]	0	hSpCas9	negative selection	11699427
7267636	7267659	19	-	28162770	HEL	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.309315098275165	[251]	[199]	2	hSpCas9	negative selection	11699428
7267572	7267595	19	-	28162770	HEL	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.45616259000788084	[304]	[267]	4	hSpCas9	negative selection	11699429
7267382	7267405	19	+	28162770	HEL	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.333534244733637	[253]	[204]	2	hSpCas9	negative selection	11699430
7184606	7184629	19	+	28162770	HEL	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.9252076917051978	[589]	[198]	-5	hSpCas9	negative selection	11699431
7184396	7184419	19	-	28162770	HEL	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-1.0025962867002811	[243]	[77]	-6	hSpCas9	negative selection	11699432
7172337	7172360	19	+	28162770	HEL	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-0.43818116338321056	[384]	[181]	-3	hSpCas9	negative selection	11699433
7184321	7184344	19	+	28162770	MV411	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	-1.0243670646787504	[98]	[40]	-6	hSpCas9	negative selection	11868790
7170658	7170681	19	+	28162770	MV411	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-1.0502429978579095	[235]	[95]	-6	hSpCas9	negative selection	11868791
7166306	7166329	19	+	28162770	MV411	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.193998291821315	[54]	[52]	1	hSpCas9	negative selection	11868792
7293792	7293815	19	-	28162770	MV411	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-0.7445251301518063	[178]	[89]	-5	hSpCas9	negative selection	11868793
7267636	7267659	19	-	28162770	MV411	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.3601376835321377	[159]	[172]	3	hSpCas9	negative selection	11868794
7267572	7267595	19	-	28162770	MV411	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.6727433855154463	[209]	[281]	6	hSpCas9	negative selection	11868795
7267382	7267405	19	+	28162770	MV411	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.7522840099115164	[252]	[358]	6	hSpCas9	negative selection	11868796
7184606	7184629	19	+	28162770	MV411	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-1.0224505260920809	[421]	[174]	-6	hSpCas9	negative selection	11868797
7184396	7184419	19	-	28162770	MV411	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	-0.16759994849606866	[187]	[140]	-1	hSpCas9	negative selection	11868798
7172337	7172360	19	+	28162770	MV411	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-1.5452705953104275	[342]	[98]	-7	hSpCas9	negative selection	11868799
7184321	7184344	19	+	28162770	MONOMAC1	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	1.5116610220838473	[66]	[218]	9	hSpCas9	negative selection	12038156
7170658	7170681	19	+	28162770	MONOMAC1	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.013004899421865723	[146]	[166]	0	hSpCas9	negative selection	12038157
7166306	7166329	19	+	28162770	MONOMAC1	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-0.016464601417732982	[29]	[33]	0	hSpCas9	negative selection	12038158
7293792	7293815	19	-	28162770	MONOMAC1	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	0.2707421142912634	[93]	[129]	2	hSpCas9	negative selection	12038159
7267636	7267659	19	-	28162770	MONOMAC1	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.21403175001634456	[90]	[120]	2	hSpCas9	negative selection	12038160
7267572	7267595	19	-	28162770	MONOMAC1	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	-0.04871410010245231	[156]	[173]	0	hSpCas9	negative selection	12038161
7267382	7267405	19	+	28162770	MONOMAC1	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.35273622519930237	[165]	[242]	3	hSpCas9	negative selection	12038162
7184606	7184629	19	+	28162770	MONOMAC1	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.40110104240933575	[217]	[329]	4	hSpCas9	negative selection	12038163
7184396	7184419	19	-	28162770	MONOMAC1	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.3216919552615157	[103]	[148]	3	hSpCas9	negative selection	12038164
7172337	7172360	19	+	28162770	MONOMAC1	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	0.12062081044958028	[202]	[252]	1	hSpCas9	negative selection	12038165
7184321	7184344	19	+	28162770	OCIAML2	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.0900851292323176	[19]	[117]	0	hSpCas9	negative selection	12207522
7170658	7170681	19	+	28162770	OCIAML2	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.32176643932767846	[45]	[203]	-3	hSpCas9	negative selection	12207523
7166306	7166329	19	+	28162770	OCIAML2	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	0.014797001928080533	[9]	[55]	0	hSpCas9	negative selection	12207524
7293792	7293815	19	-	28162770	OCIAML2	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-0.14870173035479894	[27]	[139]	-1	hSpCas9	negative selection	12207525
7267636	7267659	19	-	28162770	OCIAML2	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	0.7069083603100264	[20]	[189]	7	hSpCas9	negative selection	12207526
7267572	7267595	19	-	28162770	OCIAML2	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.2196856756252235	[43]	[283]	2	hSpCas9	negative selection	12207527
7267382	7267405	19	+	28162770	OCIAML2	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.260881338831937	[52]	[351]	2	hSpCas9	negative selection	12207528
7184606	7184629	19	+	28162770	OCIAML2	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	0.07172650410113501	[62]	[366]	0	hSpCas9	negative selection	12207529
7184396	7184419	19	-	28162770	OCIAML2	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.2383213927544483	[25]	[169]	2	hSpCas9	negative selection	12207530
7172337	7172360	19	+	28162770	OCIAML2	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-0.11009889113105154	[58]	[302]	-1	hSpCas9	negative selection	12207531
7184321	7184344	19	+	28162770	OCIAML3	viability	GGAATTCATCGTGTACCCGGAGG	INSR	ENSG00000171105	0.09565223906368636	[30]	[99]	0	hSpCas9	negative selection	12376888
7170658	7170681	19	+	28162770	OCIAML3	viability	GAAGAGTTTCCCCTGAGTGATGG	INSR	ENSG00000171105	-0.17685008917095002	[84]	[226]	-1	hSpCas9	negative selection	12376889
7166306	7166329	19	+	28162770	OCIAML3	viability	GGGTCGTTGGACCTCAGGGGTGG	INSR	ENSG00000171105	-1.5115454801321901	[16]	[17]	-8	hSpCas9	negative selection	12376890
7293792	7293815	19	-	28162770	OCIAML3	viability	GGGCCACCTGTACCCCGGAGAGG	INSR	ENSG00000171105	-1.65959598195174	[44]	[42]	-8	hSpCas9	negative selection	12376891
7267636	7267659	19	-	28162770	OCIAML3	viability	ACTGTTCTTTAACTACGCGCTGG	INSR	ENSG00000171105	-0.6611218361827003	[43]	[83]	-5	hSpCas9	negative selection	12376892
7267572	7267595	19	-	28162770	OCIAML3	viability	AACCTGATGAACATCACCCGGGG	INSR	ENSG00000171105	0.580766760779545	[65]	[297]	5	hSpCas9	negative selection	12376893
7267382	7267405	19	+	28162770	OCIAML3	viability	AAACTGCCCGTTGATGACGGTGG	INSR	ENSG00000171105	0.6758587989920561	[78]	[380]	6	hSpCas9	negative selection	12376894
7184606	7184629	19	+	28162770	OCIAML3	viability	GCAGCCGTGTGACTTACAGATGG	INSR	ENSG00000171105	-0.6564717272708167	[117]	[225]	-5	hSpCas9	negative selection	12376895
7184396	7184419	19	-	28162770	OCIAML3	viability	ACAAATGCAAGAACTCGCGGAGG	INSR	ENSG00000171105	0.09529152021172854	[39]	[128]	0	hSpCas9	negative selection	12376896
7172337	7172360	19	+	28162770	OCIAML3	viability	GGAAAGTGACACCAGAGCGTAGG	INSR	ENSG00000171105	-1.009045139603007	[123]	[185]	-6	hSpCas9	negative selection	12376897