Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:83737
• Symbol:ITCH
• Description:itchy E3 ubiquitin protein ligase

DataSource: http://genomecrispr.dkfz.de/#!/results/ITCH

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
34457389	34457412	20	+	26472758	Jiyoye	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-1.1777871192152827	[35]	[11]	-7	hSpCas9	negative selection	79535
34445290	34445313	20	+	26472758	Jiyoye	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	-0.1912703485789049	[214]	[141]	-1	hSpCas9	negative selection	79536
34424479	34424502	20	+	26472758	Jiyoye	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.14678569692764326	[108]	[90]	1	hSpCas9	negative selection	79537
34438607	34438630	20	-	26472758	Jiyoye	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.46743590632334775	[210]	[219]	3	hSpCas9	negative selection	79538
34449468	34449491	20	-	26472758	Jiyoye	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.7731702578481983	[186]	[240]	5	hSpCas9	negative selection	79539
34481142	34481165	20	+	26472758	Jiyoye	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	-0.4168758294240442	[238]	[134]	-3	hSpCas9	negative selection	79540
34489262	34489285	20	+	26472758	Jiyoye	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.12208405479888229	[144]	[118]	0	hSpCas9	negative selection	79541
34438517	34438540	20	+	26472758	Jiyoye	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.30529576748665965	[43]	[40]	2	hSpCas9	negative selection	79542
34438595	34438618	20	-	26472758	Jiyoye	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-4.334291604895274	[213]	[7]	-9	hSpCas9	negative selection	79543
34440175	34440198	20	+	26472758	Jiyoye	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	1.2001750105864075	[100]	[174]	7	hSpCas9	negative selection	79544
34457389	34457412	20	+	26472758	KBM7	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.4251261995209279	[105,85]	[15,48]	-4	hSpCas9	negative selection	270653
34445290	34445313	20	+	26472758	KBM7	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	-0.38890449652280384	[751,555]	[243,221]	-4	hSpCas9	negative selection	270654
34424479	34424502	20	+	26472758	KBM7	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.23023071750990065	[344,284]	[103,144]	-2	hSpCas9	negative selection	270655
34438607	34438630	20	-	26472758	KBM7	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.8258202390861915	[527,469]	[614,236]	8	hSpCas9	negative selection	270656
34449468	34449491	20	-	26472758	KBM7	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	-0.15627033793791334	[953,573]	[339,293]	-1	hSpCas9	negative selection	270657
34481142	34481165	20	+	26472758	KBM7	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	-0.5828113774876994	[588,451]	[180,144]	-5	hSpCas9	negative selection	270658
34489262	34489285	20	+	26472758	KBM7	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.1133796145223327	[531,757]	[381,293]	1	hSpCas9	negative selection	270659
34438517	34438540	20	+	26472758	KBM7	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	-0.6089720530403728	[265,188]	[35,98]	-5	hSpCas9	negative selection	270660
34438595	34438618	20	-	26472758	KBM7	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-1.8753405309476339	[1165,1160]	[162,137]	-8	hSpCas9	negative selection	270661
34440175	34440198	20	+	26472758	KBM7	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.23179827578954287	[554,390]	[270,245]	2	hSpCas9	negative selection	270662
34457389	34457412	20	+	26472758	Raji	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	0.06007782059524258	[61]	[14]	0	hSpCas9	negative selection	461771
34445290	34445313	20	+	26472758	Raji	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.13130937461908004	[298]	[75]	1	hSpCas9	negative selection	461772
34424479	34424502	20	+	26472758	Raji	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.25211862835461035	[198]	[54]	2	hSpCas9	negative selection	461773
34438607	34438630	20	-	26472758	Raji	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.5449636033035317	[253]	[85]	5	hSpCas9	negative selection	461774
34449468	34449491	20	-	26472758	Raji	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.7088341588833249	[318]	[120]	6	hSpCas9	negative selection	461775
34481142	34481165	20	+	26472758	Raji	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	1.0264635399900321	[219]	[103]	8	hSpCas9	negative selection	461776
34489262	34489285	20	+	26472758	Raji	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.38155849881259374	[343]	[103]	3	hSpCas9	negative selection	461777
34438517	34438540	20	+	26472758	Raji	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.8213324768148337	[138]	[56]	7	hSpCas9	negative selection	461778
34438595	34438618	20	-	26472758	Raji	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-2.983106998574308	[476]	[13]	-9	hSpCas9	negative selection	461779
34440175	34440198	20	+	26472758	Raji	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.7739598016484078	[251]	[99]	7	hSpCas9	negative selection	461780
34457389	34457412	20	+	26472758	K562	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-1.9599397708397392	[105]	[22]	-7	hSpCas9	negative selection	652889
34445290	34445313	20	+	26472758	K562	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	1.6554071222921458	[445]	[1185]	9	hSpCas9	negative selection	652890
34424479	34424502	20	+	26472758	K562	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	1.8575126636704846	[236]	[724]	9	hSpCas9	negative selection	652891
34438607	34438630	20	-	26472758	K562	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.11709009452019381	[437]	[400]	0	hSpCas9	negative selection	652892
34449468	34449491	20	-	26472758	K562	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.5421805114230569	[601]	[739]	4	hSpCas9	negative selection	652893
34481142	34481165	20	+	26472758	K562	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	0.5980556822811474	[305]	[390]	5	hSpCas9	negative selection	652894
34489262	34489285	20	+	26472758	K562	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.6987453580593476	[488]	[669]	6	hSpCas9	negative selection	652895
34438517	34438540	20	+	26472758	K562	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	1.6497875787072576	[130]	[346]	9	hSpCas9	negative selection	652896
34438595	34438618	20	-	26472758	K562	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-3.617505136930581	[915]	[62]	-9	hSpCas9	negative selection	652897
34440175	34440198	20	+	26472758	K562	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	-0.04149014441993373	[444]	[364]	0	hSpCas9	negative selection	652898
34393803	34393826	20	+	26627737	DLD1	viability	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.7157380183033157	[598]	[146,64,125]	-6	hSpCas9	negative selection	814101
34424504	34424527	20	+	26627737	DLD1	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.5591513579882812	[1338]	[549,440,819]	5	hSpCas9	negative selection	814102
34440332	34440355	20	-	26627737	DLD1	viability	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.1816543134760304	[563]	[113,237,122]	-2	hSpCas9	negative selection	814103
34445376	34445399	20	-	26627737	DLD1	viability	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.2640180299735342	[828]	[258,365,310]	2	hSpCas9	negative selection	814104
34470105	34470128	20	-	26627737	DLD1	viability	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.00583568852277927	[821]	[179,306,284]	0	hSpCas9	negative selection	814105
34479723	34479746	20	-	26627737	DLD1	viability	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.6289060722137428	[214]	[66,127,115]	6	hSpCas9	negative selection	814106
34393803	34393826	20	+	26627737	GBM cells	viability after 5 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.16281511486602052	[190]	[69,112]	-3	hSpCas9	negative selection	896416
34424504	34424527	20	+	26627737	GBM cells	viability after 5 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.03085620223284491	[861]	[432,471]	0	hSpCas9	negative selection	896417
34440332	34440355	20	-	26627737	GBM cells	viability after 5 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.32973437140545714	[249]	[174,161]	5	hSpCas9	negative selection	896418
34445376	34445399	20	-	26627737	GBM cells	viability after 5 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.11966185436945453	[468]	[195,266]	-2	hSpCas9	negative selection	896419
34470105	34470128	20	-	26627737	GBM cells	viability after 5 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.11857355184315566	[497]	[233,257]	-2	hSpCas9	negative selection	896420
34479723	34479746	20	-	26627737	GBM cells	viability after 5 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.13292537948896677	[158]	[97,88]	2	hSpCas9	negative selection	896421
34393803	34393826	20	+	26627737	GBM cells	viability after 13 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	0.1901912403586503	[190]	[104,128]	2	hSpCas9	negative selection	978731
34424504	34424527	20	+	26627737	GBM cells	viability after 13 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.05720389443891105	[861]	[479,491]	0	hSpCas9	negative selection	978732
34440332	34440355	20	-	26627737	GBM cells	viability after 13 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.03623643619513438	[249]	[139,125]	0	hSpCas9	negative selection	978733
34445376	34445399	20	-	26627737	GBM cells	viability after 13 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.019598422415019523	[468]	[295,226]	0	hSpCas9	negative selection	978734
34470105	34470128	20	-	26627737	GBM cells	viability after 13 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.09125248174576295	[497]	[326,255]	1	hSpCas9	negative selection	978735
34479723	34479746	20	-	26627737	GBM cells	viability after 13 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.3907128043332149	[158]	[111,113]	5	hSpCas9	negative selection	978736
34393803	34393826	20	+	26627737	GBM cells	viability after 21 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	0.664553339202873	[190]	[164,163]	6	hSpCas9	negative selection	1061046
34424504	34424527	20	+	26627737	GBM cells	viability after 21 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.03350781436226846	[861]	[518,442]	0	hSpCas9	negative selection	1061047
34440332	34440355	20	-	26627737	GBM cells	viability after 21 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.3387552964980818	[249]	[188,155]	3	hSpCas9	negative selection	1061048
34445376	34445399	20	-	26627737	GBM cells	viability after 21 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.12555726443526272	[468]	[313,244]	1	hSpCas9	negative selection	1061049
34470105	34470128	20	-	26627737	GBM cells	viability after 21 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.012961861755589332	[497]	[264,270]	0	hSpCas9	negative selection	1061050
34479723	34479746	20	-	26627737	GBM cells	viability after 21 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.7952069173918004	[158]	[163,136]	7	hSpCas9	negative selection	1061051
34393803	34393826	20	+	26627737	RPE1	viability after 9 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	0.12959710059024984	[737]	[257,245]	0	hSpCas9	negative selection	1143361
34424504	34424527	20	+	26627737	RPE1	viability after 9 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.6782100860028144	[1784]	[812,998]	4	hSpCas9	negative selection	1143362
34440332	34440355	20	-	26627737	RPE1	viability after 9 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.07131775785373295	[583]	[118,244]	0	hSpCas9	negative selection	1143363
34445376	34445399	20	-	26627737	RPE1	viability after 9 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.6568095704148221	[1239]	[632,584]	4	hSpCas9	negative selection	1143364
34470105	34470128	20	-	26627737	RPE1	viability after 9 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.2291943003505107	[1396]	[530,488]	1	hSpCas9	negative selection	1143365
34479723	34479746	20	-	26627737	RPE1	viability after 9 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	1.2409478144653088	[314]	[181,298]	7	hSpCas9	negative selection	1143366
34393803	34393826	20	+	26627737	RPE1	viability after 12 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.0022171704319567664	[737]	[179,216]	0	hSpCas9	negative selection	1225676
34424504	34424527	20	+	26627737	RPE1	viability after 12 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.5579274260278564	[1784]	[705,705]	3	hSpCas9	negative selection	1225677
34440332	34440355	20	-	26627737	RPE1	viability after 12 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.3102308822665297	[583]	[93,160]	-2	hSpCas9	negative selection	1225678
34445376	34445399	20	-	26627737	RPE1	viability after 12 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.2909972476773519	[1239]	[376,439]	2	hSpCas9	negative selection	1225679
34470105	34470128	20	-	26627737	RPE1	viability after 12 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.4868357286779389	[1396]	[592,454]	3	hSpCas9	negative selection	1225680
34479723	34479746	20	-	26627737	RPE1	viability after 12 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.41926936224551203	[314]	[67,160]	3	hSpCas9	negative selection	1225681
34393803	34393826	20	+	26627737	RPE1	viability after 15 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.3699336216108559	[737]	[158,163]	-2	hSpCas9	negative selection	1307991
34424504	34424527	20	+	26627737	RPE1	viability after 15 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.5952503280773938	[1784]	[856,671]	4	hSpCas9	negative selection	1307992
34440332	34440355	20	-	26627737	RPE1	viability after 15 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.4234398029077419	[583]	[112,132]	-3	hSpCas9	negative selection	1307993
34445376	34445399	20	-	26627737	RPE1	viability after 15 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.49351589471179	[1239]	[502,484]	3	hSpCas9	negative selection	1307994
34470105	34470128	20	-	26627737	RPE1	viability after 15 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.48680450466063213	[1396]	[309,254]	-3	hSpCas9	negative selection	1307995
34479723	34479746	20	-	26627737	RPE1	viability after 15 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.7657148389575664	[314]	[38,259]	5	hSpCas9	negative selection	1307996
34393803	34393826	20	+	26627737	RPE1	viability after 18 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.12457697133348405	[737]	[260,98]	-1	hSpCas9	negative selection	1390306
34424504	34424527	20	+	26627737	RPE1	viability after 18 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.7386118372194874	[1784]	[738,872]	4	hSpCas9	negative selection	1390307
34440332	34440355	20	-	26627737	RPE1	viability after 18 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.5560079596407377	[583]	[112,100]	-3	hSpCas9	negative selection	1390308
34445376	34445399	20	-	26627737	RPE1	viability after 18 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.5188524306119019	[1239]	[434,526]	3	hSpCas9	negative selection	1390309
34470105	34470128	20	-	26627737	RPE1	viability after 18 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.10676815817534424	[1396]	[367,330]	0	hSpCas9	negative selection	1390310
34479723	34479746	20	-	26627737	RPE1	viability after 18 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.8872568703625135	[314]	[134,180]	5	hSpCas9	negative selection	1390311
34393803	34393826	20	+	26627737	HeLa	viability after 8 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.30827488553507676	[598]	[242,219,177]	-3	hSpCas9	negative selection	1472621
34424504	34424527	20	+	26627737	HeLa	viability after 8 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.156630621945397	[1035]	[345,369,478]	-1	hSpCas9	negative selection	1472622
34440332	34440355	20	-	26627737	HeLa	viability after 8 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.477695999613919	[352]	[152,360,120]	4	hSpCas9	negative selection	1472623
34445376	34445399	20	-	26627737	HeLa	viability after 8 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.11161893971803472	[721]	[405,376,255]	1	hSpCas9	negative selection	1472624
34470105	34470128	20	-	26627737	HeLa	viability after 8 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.8836136009944904	[407]	[412,268,319]	7	hSpCas9	negative selection	1472625
34479723	34479746	20	-	26627737	HeLa	viability after 8 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.2978632815329716	[312]	[108,156,68]	-3	hSpCas9	negative selection	1472626
34393803	34393826	20	+	26627737	HeLa	viability after 12 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-1.039514834237252	[598]	[131,97,133]	-7	hSpCas9	negative selection	1554936
34424504	34424527	20	+	26627737	HeLa	viability after 12 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.3676159053880661	[1035]	[314,265,420]	-3	hSpCas9	negative selection	1554937
34440332	34440355	20	-	26627737	HeLa	viability after 12 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.4229550186109519	[352]	[143,178,263]	3	hSpCas9	negative selection	1554938
34445376	34445399	20	-	26627737	HeLa	viability after 12 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.21758047842301875	[721]	[178,327,252]	-2	hSpCas9	negative selection	1554939
34470105	34470128	20	-	26627737	HeLa	viability after 12 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.46673429606514744	[407]	[333,147,228]	4	hSpCas9	negative selection	1554940
34479723	34479746	20	-	26627737	HeLa	viability after 12 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.9448002989351542	[312]	[37,111,45]	-7	hSpCas9	negative selection	1554941
34393803	34393826	20	+	26627737	HeLa	viability after 15 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-1.1392291393911882	[598]	[87,162,78]	-7	hSpCas9	negative selection	1637251
34424504	34424527	20	+	26627737	HeLa	viability after 15 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.4688849244671518	[1035]	[291,333,286]	-4	hSpCas9	negative selection	1637252
34440332	34440355	20	-	26627737	HeLa	viability after 15 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.07996010061133703	[352]	[139,149,166]	0	hSpCas9	negative selection	1637253
34445376	34445399	20	-	26627737	HeLa	viability after 15 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.671142967850209	[721]	[149,185,220]	-5	hSpCas9	negative selection	1637254
34470105	34470128	20	-	26627737	HeLa	viability after 15 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	1.1185701694922507	[407]	[278,370,438]	7	hSpCas9	negative selection	1637255
34479723	34479746	20	-	26627737	HeLa	viability after 15 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.566276006325081	[312]	[96,26,137]	-5	hSpCas9	negative selection	1637256
34393803	34393826	20	+	26627737	HeLa	viability after 18 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-1.101015475931244	[598]	[59,140,78]	-7	hSpCas9	negative selection	1719566
34424504	34424527	20	+	26627737	HeLa	viability after 18 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.4538031661440409	[1035]	[196,282,286]	-4	hSpCas9	negative selection	1719567
34440332	34440355	20	-	26627737	HeLa	viability after 18 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.0686928448755751	[352]	[94,119,166]	0	hSpCas9	negative selection	1719568
34445376	34445399	20	-	26627737	HeLa	viability after 18 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.7212453379585704	[721]	[85,156,220]	-6	hSpCas9	negative selection	1719569
34470105	34470128	20	-	26627737	HeLa	viability after 18 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	1.148774708246607	[407]	[194,315,438]	7	hSpCas9	negative selection	1719570
34479723	34479746	20	-	26627737	HeLa	viability after 18 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.5036136870502336	[312]	[71,22,137]	-4	hSpCas9	negative selection	1719571
34393803	34393826	20	+	26627737	HCT116	viability after 6 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.28294545436536067	[876]	[73,134]	-1	hSpCas9	negative selection	1801881
34424504	34424527	20	+	26627737	HCT116	viability after 6 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.009793277340879203	[1199]	[323,115]	0	hSpCas9	negative selection	1801882
34440332	34440355	20	-	26627737	HCT116	viability after 6 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	1.805864974535132	[807]	[233,559]	8	hSpCas9	negative selection	1801883
34445376	34445399	20	-	26627737	HCT116	viability after 6 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.2270703225239541	[1346]	[401,58]	-1	hSpCas9	negative selection	1801884
34470105	34470128	20	-	26627737	HCT116	viability after 6 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.31907644533640944	[649]	[189,92]	1	hSpCas9	negative selection	1801885
34479723	34479746	20	-	26627737	HCT116	viability after 6 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.5335474704437495	[309]	[23,38]	-3	hSpCas9	negative selection	1801886
34393803	34393826	20	+	26627737	HCT116	viability after 8 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.14374855774210024	[283]	[123,188,111]	-2	hSpCas9	negative selection	1884196
34424504	34424527	20	+	26627737	HCT116	viability after 8 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.23207527456732358	[887]	[425,408,414]	-3	hSpCas9	negative selection	1884197
34440332	34440355	20	-	26627737	HCT116	viability after 8 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.5981432439139579	[214]	[228,138,170]	6	hSpCas9	negative selection	1884198
34445376	34445399	20	-	26627737	HCT116	viability after 8 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-1.033195953458719	[682]	[270,160,121]	-8	hSpCas9	negative selection	1884199
34470105	34470128	20	-	26627737	HCT116	viability after 8 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.1758414734795956	[383]	[199,246,268]	2	hSpCas9	negative selection	1884200
34479723	34479746	20	-	26627737	HCT116	viability after 8 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.19281422242916604	[296]	[156,246,156]	2	hSpCas9	negative selection	1884201
34393803	34393826	20	+	26627737	HCT116	viability after 9 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.7083035535794684	[876]	[144,141]	-5	hSpCas9	negative selection	1966511
34424504	34424527	20	+	26627737	HCT116	viability after 9 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.1426012993875021	[1199]	[179,490]	1	hSpCas9	negative selection	1966512
34440332	34440355	20	-	26627737	HCT116	viability after 9 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.6181017144310755	[807]	[34,223]	-4	hSpCas9	negative selection	1966513
34445376	34445399	20	-	26627737	HCT116	viability after 9 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.5366624976558234	[1346]	[257,239]	-4	hSpCas9	negative selection	1966514
34470105	34470128	20	-	26627737	HCT116	viability after 9 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.9665253211738932	[649]	[556,166]	6	hSpCas9	negative selection	1966515
34479723	34479746	20	-	26627737	HCT116	viability after 9 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.10047097127101279	[309]	[141,25]	0	hSpCas9	negative selection	1966516
34393803	34393826	20	+	26627737	HCT116	viability after 12 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.1309841181367222	[283]	[53,213,149]	-1	hSpCas9	negative selection	2048826
34424504	34424527	20	+	26627737	HCT116	viability after 12 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.20736068863432822	[887]	[391,418,402]	-2	hSpCas9	negative selection	2048827
34440332	34440355	20	-	26627737	HCT116	viability after 12 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.5078937602323903	[214]	[130,176,176]	5	hSpCas9	negative selection	2048828
34445376	34445399	20	-	26627737	HCT116	viability after 12 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.7581360382606619	[682]	[140,173,326]	-7	hSpCas9	negative selection	2048829
34470105	34470128	20	-	26627737	HCT116	viability after 12 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.04969211550868741	[383]	[158,249,222]	0	hSpCas9	negative selection	2048830
34479723	34479746	20	-	26627737	HCT116	viability after 12 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.11248741481001136	[296]	[82,137,291]	1	hSpCas9	negative selection	2048831
34393803	34393826	20	+	26627737	HCT116	viability after 15 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.2414732811387642	[283]	[100,220,87]	-3	hSpCas9	negative selection	2131141
34424504	34424527	20	+	26627737	HCT116	viability after 15 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.20288338874475498	[887]	[581,393,370]	-2	hSpCas9	negative selection	2131142
34440332	34440355	20	-	26627737	HCT116	viability after 15 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.6962234442012443	[214]	[242,211,150]	6	hSpCas9	negative selection	2131143
34445376	34445399	20	-	26627737	HCT116	viability after 15 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-1.036544181703031	[682]	[154,202,210]	-8	hSpCas9	negative selection	2131144
34470105	34470128	20	-	26627737	HCT116	viability after 15 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.08129555654120174	[383]	[241,226,160]	-1	hSpCas9	negative selection	2131145
34479723	34479746	20	-	26627737	HCT116	viability after 15 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.5677342449854466	[296]	[119,124,100]	-5	hSpCas9	negative selection	2131146
34393803	34393826	20	+	26627737	HCT116	viability after 18 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	0.5437658183413134	[283]	[110,214,276]	4	hSpCas9	negative selection	2213456
34424504	34424527	20	+	26627737	HCT116	viability after 18 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.012223947665844559	[887]	[601,387,282]	0	hSpCas9	negative selection	2213457
34440332	34440355	20	-	26627737	HCT116	viability after 18 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.38658508832923333	[214]	[127,118,162]	3	hSpCas9	negative selection	2213458
34445376	34445399	20	-	26627737	HCT116	viability after 18 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.6624090408937235	[682]	[247,199,176]	-6	hSpCas9	negative selection	2213459
34470105	34470128	20	-	26627737	HCT116	viability after 18 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.6536690933012397	[383]	[318,307,245]	5	hSpCas9	negative selection	2213460
34479723	34479746	20	-	26627737	HCT116	viability after 18 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	0.016258314917538638	[296]	[148,131,155]	0	hSpCas9	negative selection	2213461
34413738	34413761	20	-	24336569	HL60	viability	GTCACAACTACTTCTTCAACTGG	ITCH	ENSG00000078747	-0.5643015851222	[667]	[955]	-5	hSpCas9	negative selection	2272351
34413750	34413773	20	+	24336569	HL60	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	-1.315136446831347	[106]	[90]	-8	hSpCas9	negative selection	2272352
34413780	34413803	20	+	24336569	HL60	viability	AAAGAGCCAACAGAGACAATAGG	ITCH	ENSG00000078747	1.1938033342810817	[640]	[3102]	8	hSpCas9	negative selection	2272353
34413786	34413809	20	-	24336569	HL60	viability	AAGTCTCCTATTGTCTCTGTTGG	ITCH	ENSG00000078747	0.7715926797348633	[252]	[913]	6	hSpCas9	negative selection	2272354
34413804	34413827	20	+	24336569	HL60	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	-0.643872285181155	[713]	[966]	-5	hSpCas9	negative selection	2272355
34413837	34413860	20	+	24336569	HL60	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	-0.4364097301735399	[336]	[526]	-4	hSpCas9	negative selection	2272356
34413853	34413876	20	-	24336569	HL60	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.651826633459269	[466]	[628]	-5	hSpCas9	negative selection	2272357
34424479	34424502	20	+	24336569	HL60	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.03181808234757072	[456]	[945]	0	hSpCas9	negative selection	2272358
34424493	34424516	20	+	24336569	HL60	viability	TGATGATGGCTCCAGATCCAAGG	ITCH	ENSG00000078747	1.307479202498803	[264]	[1387]	8	hSpCas9	negative selection	2272359
34424504	34424527	20	+	24336569	HL60	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.38631868215731713	[1049]	[1699]	-3	hSpCas9	negative selection	2272360
34413738	34413761	20	-	24336569	KBM7	viability	GTCACAACTACTTCTTCAACTGG	ITCH	ENSG00000078747	0.08449266551519169	[462]	[1338]	0	hSpCas9	negative selection	2339528
34413750	34413773	20	+	24336569	KBM7	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	-0.7086653305931547	[147]	[246]	-5	hSpCas9	negative selection	2339529
34413780	34413803	20	+	24336569	KBM7	viability	AAAGAGCCAACAGAGACAATAGG	ITCH	ENSG00000078747	0.24458236348387508	[846]	[2736]	2	hSpCas9	negative selection	2339530
34413786	34413809	20	-	24336569	KBM7	viability	AAGTCTCCTATTGTCTCTGTTGG	ITCH	ENSG00000078747	0.5932064182976176	[278]	[1147]	5	hSpCas9	negative selection	2339531
34413804	34413827	20	+	24336569	KBM7	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.5300391097462734	[405]	[1598]	5	hSpCas9	negative selection	2339532
34413837	34413860	20	+	24336569	KBM7	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.33203073502581737	[359]	[1235]	3	hSpCas9	negative selection	2339533
34413853	34413876	20	-	24336569	KBM7	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	0.0006251666651606591	[257]	[703]	0	hSpCas9	negative selection	2339534
34424479	34424502	20	+	24336569	KBM7	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.37529311585045155	[250]	[887]	3	hSpCas9	negative selection	2339535
34424493	34424516	20	+	24336569	KBM7	viability	TGATGATGGCTCCAGATCCAAGG	ITCH	ENSG00000078747	-0.1800321344211776	[664]	[1600]	-1	hSpCas9	negative selection	2339536
34424504	34424527	20	+	24336569	KBM7	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.9083113093054691	[444]	[2277]	7	hSpCas9	negative selection	2339537
34456587	34456610	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACGCCACTGCACTCCAGCCAGG	ITCH	ENSG00000078747	-0.23120917697478569	[21,115]	[6,17]	-1	dCas9-VP64	positive selection	2389374
34487207	34487230	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTTCACCGTGTTAGCCAGGAAAG	ITCH	ENSG00000078747	0.2955844688889684	[184,570]	[130,72]	1	dCas9-VP64	positive selection	2398453
34435427	34435450	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCCCAGCACTTAAG	ITCH	ENSG00000078747	-0.9680503266497309	[486,330]	[14,78]	-5	dCas9-VP64	positive selection	2398723
34378225	34378248	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTTTGGGAGGCCAAGGCGGGAGG	ITCH	ENSG00000078747	0.09588317305989913	[114,12]	[10,18]	0	dCas9-VP64	positive selection	2411190
34388446	34388469	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGCTGCAGTGAGCTGTGATAAG	ITCH	ENSG00000078747	-0.2191175493670201	[259,121]	[39,30]	-1	dCas9-VP64	positive selection	2411996
34375083	34375106	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGCGCCATTGCACTCCAGCTGGG	ITCH	ENSG00000078747	0.14794526525316742	[282,182]	[37,75]	0	dCas9-VP64	positive selection	2421128
34387437	34387460	20	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGGTCTCACTATATTGCCCGGG	ITCH	ENSG00000078747	2.346297348584061	[172,220]	[56,398]	7	dCas9-VP64	positive selection	2428385
34397193	34397216	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TTGCATTTTTAATAGAGACGAGG	ITCH	ENSG00000078747	-0.26285040717771335	[141,96]	[27,13]	-1	dCas9-VP64	positive selection	2431610
34417472	34417495	20	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCACTACAACCTCTGCCTCCCGG	ITCH	ENSG00000078747	0.3736894149735144	[619,564]	[67,277]	1	dCas9-VP64	positive selection	2444028
34456587	34456610	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACGCCACTGCACTCCAGCCAGG	ITCH	ENSG00000078747	-0.7543799798568478	[117,158]	[37,14]	-7	dCas9-VP64	positive selection	2484629
34487207	34487230	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTTCACCGTGTTAGCCAGGAAAG	ITCH	ENSG00000078747	1.071805523628855	[383,191]	[227,172]	7	dCas9-VP64	positive selection	2493708
34435427	34435450	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCCCAGCACTTAAG	ITCH	ENSG00000078747	0.18483027177666878	[252,653]	[84,243]	1	dCas9-VP64	positive selection	2493978
34378225	34378248	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTTTGGGAGGCCAAGGCGGGAGG	ITCH	ENSG00000078747	3.077269363618506	[19,18]	[13,93]	9	dCas9-VP64	positive selection	2506445
34388446	34388469	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGCTGCAGTGAGCTGTGATAAG	ITCH	ENSG00000078747	-0.13774130468097318	[186,55]	[21,49]	-1	dCas9-VP64	positive selection	2507251
34375083	34375106	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGCGCCATTGCACTCCAGCTGGG	ITCH	ENSG00000078747	-0.3408601233544918	[134,323]	[46,68]	-3	dCas9-VP64	positive selection	2516383
34387437	34387460	20	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGGTCTCACTATATTGCCCGGG	ITCH	ENSG00000078747	-0.41126224133599143	[350,385]	[99,80]	-4	dCas9-VP64	positive selection	2523640
34397193	34397216	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TTGCATTTTTAATAGAGACGAGG	ITCH	ENSG00000078747	1.0123186104573552	[17,472]	[10,297]	6	dCas9-VP64	positive selection	2526865
34417472	34417495	20	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCACTACAACCTCTGCCTCCCGG	ITCH	ENSG00000078747	2.2699980135687987	[309,268]	[879,61]	8	dCas9-VP64	positive selection	2539283
34445361	34445384	20	+	27260157	DLD1	viability	GGCCAACACTGGAATCCGTCCGG	ITCH	ENSG00000078747	0.956990071663517	[]	[]	9	hSpCas9	negative selection	2573626
34413837	34413860	20	+	27260157	DLD1	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	-0.245855818644336	[]	[]	-2	hSpCas9	negative selection	2578095
34438617	34438640	20	-	27260157	DLD1	viability	ATACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.267330540298844	[]	[]	4	hSpCas9	negative selection	2579958
34413780	34413803	20	+	27260157	DLD1	viability	AAAGAGCCAACAGAGACAATAGG	ITCH	ENSG00000078747	0.234877787683895	[]	[]	4	hSpCas9	negative selection	2580497
34408691	34408714	20	+	27260157	DLD1	viability	TGGACCAAGTCCTTACGTAGAGG	ITCH	ENSG00000078747	-0.433798039021456	[]	[]	-4	hSpCas9	negative selection	2583096
34424479	34424502	20	+	27260157	DLD1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.303995558963701	[]	[]	-2	hSpCas9	negative selection	2583111
34424504	34424527	20	-	27260157	DLD1	viability	CCTTGTTTCATCCTTGGATCTGG	ITCH	ENSG00000078747	-0.780189898670241	[]	[]	-6	hSpCas9	negative selection	2583295
34408704	34408727	20	+	27260157	DLD1	viability	TACGTAGAGGTCACAGTAGATGG	ITCH	ENSG00000078747	-0.169971295630228	[]	[]	-1	hSpCas9	negative selection	2604285
34424504	34424527	20	+	27260157	DLD1	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.718744317096383	[]	[]	8	hSpCas9	negative selection	2607966
34393796	34393819	20	-	27260157	DLD1	viability	CAGACATACCACCAATAGGTTGG	ITCH	ENSG00000078747	-0.434648845796773	[]	[]	-4	hSpCas9	negative selection	2612106
34413750	34413773	20	+	27260157	DLD1	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.818769354595387	[]	[]	9	hSpCas9	negative selection	2613699
34442226	34442249	20	-	27260157	DLD1	viability	CATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-1.12447544074532	[]	[]	-7	hSpCas9	negative selection	2616055
34424493	34424516	20	+	27260157	DLD1	viability	TGATGATGGCTCCAGATCCAAGG	ITCH	ENSG00000078747	1.11892516580055	[]	[]	9	hSpCas9	negative selection	2616391
34445363	34445386	20	-	27260157	DLD1	viability	TTCCGGACGGATTCCAGTGTTGG	ITCH	ENSG00000078747	0.133287167960991	[]	[]	3	hSpCas9	negative selection	2616668
34445376	34445399	20	+	27260157	DLD1	viability	CCGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	-0.207591116553864	[]	[]	-1	hSpCas9	negative selection	2617008
34413853	34413876	20	-	27260157	DLD1	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.806711960898547	[]	[]	-6	hSpCas9	negative selection	2620662
34408695	34408718	20	-	27260157	DLD1	viability	GTGACCTCTACGTAAGGACTTGG	ITCH	ENSG00000078747	0.68935109466658	[]	[]	8	hSpCas9	negative selection	2621050
34413786	34413809	20	-	27260157	DLD1	viability	AAGTCTCCTATTGTCTCTGTTGG	ITCH	ENSG00000078747	-0.0633254976333644	[]	[]	0	hSpCas9	negative selection	2642108
34413738	34413761	20	-	27260157	DLD1	viability	GTCACAACTACTTCTTCAACTGG	ITCH	ENSG00000078747	-0.364620017808316	[]	[]	-3	hSpCas9	negative selection	2644659
34413804	34413827	20	+	27260157	DLD1	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	-0.0688334120033397	[]	[]	0	hSpCas9	negative selection	2649432
34445361	34445384	20	+	27260157	HT1080	viability	GGCCAACACTGGAATCCGTCCGG	ITCH	ENSG00000078747	-0.20819210890659	[]	[]	0	hSpCas9	negative selection	2649756
34413837	34413860	20	+	27260157	HT1080	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.334002397316259	[]	[]	3	hSpCas9	negative selection	2654225
34438617	34438640	20	-	27260157	HT1080	viability	ATACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.459083908881877	[]	[]	4	hSpCas9	negative selection	2656088
34413780	34413803	20	+	27260157	HT1080	viability	AAAGAGCCAACAGAGACAATAGG	ITCH	ENSG00000078747	0.761394694560112	[]	[]	6	hSpCas9	negative selection	2656627
34408691	34408714	20	+	27260157	HT1080	viability	TGGACCAAGTCCTTACGTAGAGG	ITCH	ENSG00000078747	-0.246986655229564	[]	[]	0	hSpCas9	negative selection	2659226
34424479	34424502	20	+	27260157	HT1080	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.313507048911444	[]	[]	-7	hSpCas9	negative selection	2659241
34424504	34424527	20	-	27260157	HT1080	viability	CCTTGTTTCATCCTTGGATCTGG	ITCH	ENSG00000078747	-1.91393048255048	[]	[]	-9	hSpCas9	negative selection	2659425
34408704	34408727	20	+	27260157	HT1080	viability	TACGTAGAGGTCACAGTAGATGG	ITCH	ENSG00000078747	0.776412887697053	[]	[]	6	hSpCas9	negative selection	2680415
34424504	34424527	20	+	27260157	HT1080	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	1.55437959402329	[]	[]	9	hSpCas9	negative selection	2684096
34393796	34393819	20	-	27260157	HT1080	viability	CAGACATACCACCAATAGGTTGG	ITCH	ENSG00000078747	-0.311532412452659	[]	[]	-7	hSpCas9	negative selection	2688236
34413750	34413773	20	+	27260157	HT1080	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.697309884012385	[]	[]	6	hSpCas9	negative selection	2689829
34442226	34442249	20	-	27260157	HT1080	viability	CATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.938768677653093	[]	[]	-8	hSpCas9	negative selection	2692185
34424493	34424516	20	+	27260157	HT1080	viability	TGATGATGGCTCCAGATCCAAGG	ITCH	ENSG00000078747	1.49721321613586	[]	[]	9	hSpCas9	negative selection	2692521
34445363	34445386	20	-	27260157	HT1080	viability	TTCCGGACGGATTCCAGTGTTGG	ITCH	ENSG00000078747	0.979729277218579	[]	[]	8	hSpCas9	negative selection	2692798
34445376	34445399	20	+	27260157	HT1080	viability	CCGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	-0.0394871160223326	[]	[]	0	hSpCas9	negative selection	2693138
34413853	34413876	20	-	27260157	HT1080	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.781059014062916	[]	[]	-8	hSpCas9	negative selection	2696792
34408695	34408718	20	-	27260157	HT1080	viability	GTGACCTCTACGTAAGGACTTGG	ITCH	ENSG00000078747	0.619392493811715	[]	[]	5	hSpCas9	negative selection	2697180
34413786	34413809	20	-	27260157	HT1080	viability	AAGTCTCCTATTGTCTCTGTTGG	ITCH	ENSG00000078747	0.00723899821337369	[]	[]	0	hSpCas9	negative selection	2718238
34413738	34413761	20	-	27260157	HT1080	viability	GTCACAACTACTTCTTCAACTGG	ITCH	ENSG00000078747	0.276510168767031	[]	[]	2	hSpCas9	negative selection	2720789
34413804	34413827	20	+	27260157	HT1080	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.185199606114082	[]	[]	1	hSpCas9	negative selection	2725562
34445361	34445384	20	+	27260157	MKN45	viability	GGCCAACACTGGAATCCGTCCGG	ITCH	ENSG00000078747	0.51914423356232	[]	[]	6	hSpCas9	negative selection	2725886
34413837	34413860	20	+	27260157	MKN45	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.572911197001311	[]	[]	7	hSpCas9	negative selection	2730355
34438617	34438640	20	-	27260157	MKN45	viability	ATACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	-0.752986995965514	[]	[]	-7	hSpCas9	negative selection	2732218
34413780	34413803	20	+	27260157	MKN45	viability	AAAGAGCCAACAGAGACAATAGG	ITCH	ENSG00000078747	0.489759259365694	[]	[]	6	hSpCas9	negative selection	2732757
34408691	34408714	20	+	27260157	MKN45	viability	TGGACCAAGTCCTTACGTAGAGG	ITCH	ENSG00000078747	-1.2213270105876	[]	[]	-8	hSpCas9	negative selection	2735356
34424479	34424502	20	+	27260157	MKN45	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.826427112491183	[]	[]	-7	hSpCas9	negative selection	2735371
34424504	34424527	20	-	27260157	MKN45	viability	CCTTGTTTCATCCTTGGATCTGG	ITCH	ENSG00000078747	-0.690398634044605	[]	[]	-7	hSpCas9	negative selection	2735555
34408704	34408727	20	+	27260157	MKN45	viability	TACGTAGAGGTCACAGTAGATGG	ITCH	ENSG00000078747	0.271713666056135	[]	[]	5	hSpCas9	negative selection	2756545
34424504	34424527	20	+	27260157	MKN45	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.969032158016318	[]	[]	8	hSpCas9	negative selection	2760226
34393796	34393819	20	-	27260157	MKN45	viability	CAGACATACCACCAATAGGTTGG	ITCH	ENSG00000078747	-0.530891383560787	[]	[]	-6	hSpCas9	negative selection	2764366
34413750	34413773	20	+	27260157	MKN45	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	-0.0892053524623183	[]	[]	0	hSpCas9	negative selection	2765959
34442226	34442249	20	-	27260157	MKN45	viability	CATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-1.25129742455873	[]	[]	-8	hSpCas9	negative selection	2768315
34424493	34424516	20	+	27260157	MKN45	viability	TGATGATGGCTCCAGATCCAAGG	ITCH	ENSG00000078747	0.887357065076862	[]	[]	8	hSpCas9	negative selection	2768651
34445363	34445386	20	-	27260157	MKN45	viability	TTCCGGACGGATTCCAGTGTTGG	ITCH	ENSG00000078747	0.100358043954453	[]	[]	0	hSpCas9	negative selection	2768928
34445376	34445399	20	+	27260157	MKN45	viability	CCGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	-0.408263490097501	[]	[]	-6	hSpCas9	negative selection	2769268
34413853	34413876	20	-	27260157	MKN45	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-1.03487032249393	[]	[]	-8	hSpCas9	negative selection	2772922
34408695	34408718	20	-	27260157	MKN45	viability	GTGACCTCTACGTAAGGACTTGG	ITCH	ENSG00000078747	1.2821592176905	[]	[]	9	hSpCas9	negative selection	2773310
34413786	34413809	20	-	27260157	MKN45	viability	AAGTCTCCTATTGTCTCTGTTGG	ITCH	ENSG00000078747	-0.281908125916161	[]	[]	-1	hSpCas9	negative selection	2794368
34413738	34413761	20	-	27260157	MKN45	viability	GTCACAACTACTTCTTCAACTGG	ITCH	ENSG00000078747	0.19147574406189	[]	[]	5	hSpCas9	negative selection	2796919
34413804	34413827	20	+	27260157	MKN45	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	1.11259040735902	[]	[]	8	hSpCas9	negative selection	2801692
34445361	34445384	20	+	27260157	RKO	viability	GGCCAACACTGGAATCCGTCCGG	ITCH	ENSG00000078747	-0.073212203442641	[]	[]	0	hSpCas9	negative selection	2802016
34413837	34413860	20	+	27260157	RKO	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.0282353556588824	[]	[]	0	hSpCas9	negative selection	2806485
34438617	34438640	20	-	27260157	RKO	viability	ATACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	-0.992776535340087	[]	[]	-8	hSpCas9	negative selection	2808348
34413780	34413803	20	+	27260157	RKO	viability	AAAGAGCCAACAGAGACAATAGG	ITCH	ENSG00000078747	-0.25530101991191	[]	[]	-1	hSpCas9	negative selection	2808887
34408691	34408714	20	+	27260157	RKO	viability	TGGACCAAGTCCTTACGTAGAGG	ITCH	ENSG00000078747	-0.35102592774329	[]	[]	-6	hSpCas9	negative selection	2811486
34424479	34424502	20	+	27260157	RKO	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.662113082840486	[]	[]	-7	hSpCas9	negative selection	2811501
34424504	34424527	20	-	27260157	RKO	viability	CCTTGTTTCATCCTTGGATCTGG	ITCH	ENSG00000078747	-1.61540251682446	[]	[]	-9	hSpCas9	negative selection	2811685
34408704	34408727	20	+	27260157	RKO	viability	TACGTAGAGGTCACAGTAGATGG	ITCH	ENSG00000078747	-0.203448244593939	[]	[]	-1	hSpCas9	negative selection	2832675
34424504	34424527	20	+	27260157	RKO	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.699763428465216	[]	[]	8	hSpCas9	negative selection	2836356
34393796	34393819	20	-	27260157	RKO	viability	CAGACATACCACCAATAGGTTGG	ITCH	ENSG00000078747	-0.42608709525256	[]	[]	-6	hSpCas9	negative selection	2840496
34413750	34413773	20	+	27260157	RKO	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	-1.31772252960527	[]	[]	-8	hSpCas9	negative selection	2842089
34442226	34442249	20	-	27260157	RKO	viability	CATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-1.25051216505854	[]	[]	-8	hSpCas9	negative selection	2844445
34424493	34424516	20	+	27260157	RKO	viability	TGATGATGGCTCCAGATCCAAGG	ITCH	ENSG00000078747	1.47781502761295	[]	[]	9	hSpCas9	negative selection	2844781
34445363	34445386	20	-	27260157	RKO	viability	TTCCGGACGGATTCCAGTGTTGG	ITCH	ENSG00000078747	0.207249580432714	[]	[]	1	hSpCas9	negative selection	2845058
34445376	34445399	20	+	27260157	RKO	viability	CCGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	-0.0727552370367997	[]	[]	0	hSpCas9	negative selection	2845398
34413853	34413876	20	-	27260157	RKO	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.162751140192492	[]	[]	-1	hSpCas9	negative selection	2849052
34408695	34408718	20	-	27260157	RKO	viability	GTGACCTCTACGTAAGGACTTGG	ITCH	ENSG00000078747	0.607835053625028	[]	[]	3	hSpCas9	negative selection	2849440
34413786	34413809	20	-	27260157	RKO	viability	AAGTCTCCTATTGTCTCTGTTGG	ITCH	ENSG00000078747	-0.595634596329189	[]	[]	-7	hSpCas9	negative selection	2870498
34413738	34413761	20	-	27260157	RKO	viability	GTCACAACTACTTCTTCAACTGG	ITCH	ENSG00000078747	0.0101759358959064	[]	[]	0	hSpCas9	negative selection	2873049
34413804	34413827	20	+	27260157	RKO	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	1.04909859506563	[]	[]	9	hSpCas9	negative selection	2877822
34445361	34445384	20	+	27260157	SF268	viability	GGCCAACACTGGAATCCGTCCGG	ITCH	ENSG00000078747	1.01967314997793	[]	[]	9	hSpCas9	negative selection	2878146
34413837	34413860	20	+	27260157	SF268	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	1.0600129199968	[]	[]	9	hSpCas9	negative selection	2882615
34438617	34438640	20	-	27260157	SF268	viability	ATACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	-0.534624021652091	[]	[]	-4	hSpCas9	negative selection	2884478
34413780	34413803	20	+	27260157	SF268	viability	AAAGAGCCAACAGAGACAATAGG	ITCH	ENSG00000078747	0.453561657529134	[]	[]	7	hSpCas9	negative selection	2885017
34408691	34408714	20	+	27260157	SF268	viability	TGGACCAAGTCCTTACGTAGAGG	ITCH	ENSG00000078747	-0.601169073131879	[]	[]	-5	hSpCas9	negative selection	2887616
34424479	34424502	20	+	27260157	SF268	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.907081321811598	[]	[]	-6	hSpCas9	negative selection	2887631
34424504	34424527	20	-	27260157	SF268	viability	CCTTGTTTCATCCTTGGATCTGG	ITCH	ENSG00000078747	-1.01036356843253	[]	[]	-7	hSpCas9	negative selection	2887815
34408704	34408727	20	+	27260157	SF268	viability	TACGTAGAGGTCACAGTAGATGG	ITCH	ENSG00000078747	0.290295389634456	[]	[]	4	hSpCas9	negative selection	2908805
34424504	34424527	20	+	27260157	SF268	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.979165198035518	[]	[]	9	hSpCas9	negative selection	2912486
34393796	34393819	20	-	27260157	SF268	viability	CAGACATACCACCAATAGGTTGG	ITCH	ENSG00000078747	-0.231877890879528	[]	[]	-2	hSpCas9	negative selection	2916626
34413750	34413773	20	+	27260157	SF268	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.406619236142478	[]	[]	4	hSpCas9	negative selection	2918219
34442226	34442249	20	-	27260157	SF268	viability	CATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-1.30568129408849	[]	[]	-7	hSpCas9	negative selection	2920575
34424493	34424516	20	+	27260157	SF268	viability	TGATGATGGCTCCAGATCCAAGG	ITCH	ENSG00000078747	1.3980325239761	[]	[]	9	hSpCas9	negative selection	2920911
34445363	34445386	20	-	27260157	SF268	viability	TTCCGGACGGATTCCAGTGTTGG	ITCH	ENSG00000078747	0.491749296837145	[]	[]	7	hSpCas9	negative selection	2921188
34445376	34445399	20	+	27260157	SF268	viability	CCGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.682046135276114	[]	[]	8	hSpCas9	negative selection	2921528
34413853	34413876	20	-	27260157	SF268	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	0.0592372832456972	[]	[]	0	hSpCas9	negative selection	2925182
34408695	34408718	20	-	27260157	SF268	viability	GTGACCTCTACGTAAGGACTTGG	ITCH	ENSG00000078747	0.849073196058416	[]	[]	9	hSpCas9	negative selection	2925570
34413786	34413809	20	-	27260157	SF268	viability	AAGTCTCCTATTGTCTCTGTTGG	ITCH	ENSG00000078747	0.039327188682339	[]	[]	0	hSpCas9	negative selection	2946628
34413738	34413761	20	-	27260157	SF268	viability	GTCACAACTACTTCTTCAACTGG	ITCH	ENSG00000078747	1.87071667813696e-05	[]	[]	0	hSpCas9	negative selection	2949179
34413804	34413827	20	+	27260157	SF268	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	1.19419740067497	[]	[]	9	hSpCas9	negative selection	2953952
34445335	34445358	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATTTCACAAGAACAACAACGTGG	ITCH	ENSG00000078747	0.3291904254126684	[4,4]	[5,5]	7	hSpCas9	positive selection	2996089
34445376	34445399	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.30384168853403326	[5,5]	[6,5]	6	hSpCas9	positive selection	2996090
34440274	34440297	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCCTCCAGATATAGTAAGAGG	ITCH	ENSG00000078747	0.523965803246718	[4,3]	[3,5]	9	hSpCas9	positive selection	2996091
34449468	34449491	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.09837139355834049	[3,3]	[4,2]	2	hSpCas9	positive selection	2996092
34445335	34445358	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATTTCACAAGAACAACAACGTGG	ITCH	ENSG00000078747	0.6731473160725951	[4,4]	[5,5]	9	hSpCas9	positive selection	3063947
34445376	34445399	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.4133484414210832	[5,5]	[5,4]	7	hSpCas9	positive selection	3063948
34440274	34440297	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCCTCCAGATATAGTAAGAGG	ITCH	ENSG00000078747	0.3942801983434989	[4,4]	[3,3]	7	hSpCas9	positive selection	3063949
34449468	34449491	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.5728700364202197	[3,3]	[4,3]	8	hSpCas9	positive selection	3063950
34412525	34412548		-	24336571	A375	resistance to PLX after 7 days	CGAAAATGTAATTTACTCACAGG	ITCH	ENSG00000078747	0.05031196394386017	[19,17]	[18,19]	1	hSpCas9	positive selection	3121698
34412532	34412555		+	24336571	A375	resistance to PLX after 7 days	GTAAATTACATTTTCGTGTGTGG	ITCH	ENSG00000078747	0.0818087585419677	[14,15]	[15,15]	3	hSpCas9	positive selection	3121699
34413750	34413773		+	24336571	A375	resistance to PLX after 7 days	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	-0.07791909566078203	[23,26]	[24,23]	-2	hSpCas9	positive selection	3121700
34412525	34412548		-	24336571	A375	resistance to PLX after 14 days	CGAAAATGTAATTTACTCACAGG	ITCH	ENSG00000078747	-0.89068666674927	[20,23]	[4,4]	-9	hSpCas9	positive selection	3179491
34412532	34412555		+	24336571	A375	resistance to PLX after 14 days	GTAAATTACATTTTCGTGTGTGG	ITCH	ENSG00000078747	-0.0038409068627913157	[17,14]	[7,6]	0	hSpCas9	positive selection	3179492
34413750	34413773		+	24336571	A375	resistance to PLX after 14 days	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	-0.11520451805376886	[35,26]	[11,13]	-1	hSpCas9	positive selection	3179493
34412525	34412548		-	24336571	A375	viability after 7 days	CGAAAATGTAATTTACTCACAGG	ITCH	ENSG00000078747	-0.6602209088955151	[31]	[19,17]	-7	hSpCas9	negative selection	3237284
34412532	34412555		+	24336571	A375	viability after 7 days	GTAAATTACATTTTCGTGTGTGG	ITCH	ENSG00000078747	0.07586712265480569	[14]	[14,15]	1	hSpCas9	negative selection	3237285
34413750	34413773		+	24336571	A375	viability after 7 days	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.3289171182246773	[20]	[23,26]	5	hSpCas9	negative selection	3237286
34412525	34412548		-	24336571	A375	viability after 14 days	CGAAAATGTAATTTACTCACAGG	ITCH	ENSG00000078747	-0.40038148161348397	[31]	[20,23]	-5	hSpCas9	negative selection	3295077
34412532	34412555		+	24336571	A375	viability after 14 days	GTAAATTACATTTTCGTGTGTGG	ITCH	ENSG00000078747	0.1991196816103631	[14]	[17,14]	2	hSpCas9	negative selection	3295078
34413750	34413773		+	24336571	A375	viability after 14 days	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.6436244506445741	[20]	[35,26]	7	hSpCas9	negative selection	3295079
34424479	34424502	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3374725
34413853	34413876	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.753901043977419	[515,515]	[1,1]	-5	hSpCas9	positive selection	3374726
34413804	34413827	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	-0.5881638394985401	[229,229]	[0,0]	-4	hSpCas9	positive selection	3374727
34445334	34445357	20	+	26780180	HT29	viability (Avana library 4 designs)	ATTTCACAAGAACAACAACGTGG	ITCH	ENSG00000078747	-0.345506615749079	[]	[]	-5	hSpCas9	negative selection	3433481
34445376	34445399	20	-	26780180	HT29	viability (Avana library 4 designs)	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.601278750137896	[]	[]	-8	hSpCas9	negative selection	3433482
34440274	34440297	20	-	26780180	HT29	viability (Avana library 4 designs)	GAGCCTCCAGATATAGTAAGAGG	ITCH	ENSG00000078747	-0.0292919656667819	[]	[]	0	hSpCas9	negative selection	3433483
34449468	34449491	20	-	26780180	HT29	viability (Avana library 4 designs)	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.360049740612798	[]	[]	1	hSpCas9	negative selection	3433484
34445376	34445399	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-1.89621310227867	[]	[]	-2	hSpCas9	negative selection	3520113
34449468	34449491	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	-0.436506853481409	[]	[]	0	hSpCas9	negative selection	3520114
34445334	34445357	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATTTCACAAGAACAACAACGTGG	ITCH	ENSG00000078747	-9.10857265144167	[]	[]	-7	hSpCas9	negative selection	3520115
34440274	34440297	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCCTCCAGATATAGTAAGAGG	ITCH	ENSG00000078747	1.96512122242501	[]	[]	3	hSpCas9	negative selection	3520116
34462123	34462146	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTGGGAAATGAGATTCACAGTGG	ITCH	ENSG00000078747	-6.4498652711333	[]	[]	-6	hSpCas9	negative selection	3520117
34438586	34438609	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTGGTCGTGAAGGTCTTGGAGG	ITCH	ENSG00000078747	3.53455864612757	[]	[]	5	hSpCas9	negative selection	3520118
34445376	34445399	20	-	26780180	A375	viability (Avana lentiGuide)	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	5.67077935511545	[]	[]	5	hSpCas9	negative selection	3628772
34449468	34449491	20	-	26780180	A375	viability (Avana lentiGuide)	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	15.2490281093857	[]	[]	8	hSpCas9	negative selection	3628773
34445334	34445357	20	+	26780180	A375	viability (Avana lentiGuide)	ATTTCACAAGAACAACAACGTGG	ITCH	ENSG00000078747	5.99392947700901	[]	[]	5	hSpCas9	negative selection	3628774
34440274	34440297	20	-	26780180	A375	viability (Avana lentiGuide)	GAGCCTCCAGATATAGTAAGAGG	ITCH	ENSG00000078747	7.87139880601262	[]	[]	6	hSpCas9	negative selection	3628775
34462123	34462146	20	+	26780180	A375	viability (Avana lentiGuide)	TTGGGAAATGAGATTCACAGTGG	ITCH	ENSG00000078747	13.4243214403409	[]	[]	7	hSpCas9	negative selection	3628776
34438586	34438609	20	-	26780180	A375	viability (Avana lentiGuide)	GGTGGTCGTGAAGGTCTTGGAGG	ITCH	ENSG00000078747	3.26989897350482	[]	[]	3	hSpCas9	negative selection	3628777
34445376	34445399	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.16113248032368443	[6]	[4,5]	-3	hSpCas9	positive selection	3737431
34449468	34449491	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	-0.1377721683993142	[4]	[5,3]	-2	hSpCas9	positive selection	3737432
34445334	34445357	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATTTCACAAGAACAACAACGTGG	ITCH	ENSG00000078747	-0.7503749243989393	[6]	[4,2]	-8	hSpCas9	positive selection	3737433
34440274	34440297	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCCTCCAGATATAGTAAGAGG	ITCH	ENSG00000078747	0.15508797051644085	[5]	[5,5]	4	hSpCas9	positive selection	3737434
34462123	34462146	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGGGAAATGAGATTCACAGTGG	ITCH	ENSG00000078747	-0.5795795082868458	[5]	[3,2]	-7	hSpCas9	positive selection	3737435
34438586	34438609	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTGGTCGTGAAGGTCTTGGAGG	ITCH	ENSG00000078747	0.05257063185989414	[4]	[4,4]	1	hSpCas9	positive selection	3737436
34445376	34445399	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.08227818505391671	[7]	[5,6]	1	hSpCas9	positive selection	3846038
34449468	34449491	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	-1.351320194673926	[5]	[2,0]	-9	hSpCas9	positive selection	3846039
34445334	34445357	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATTTCACAAGAACAACAACGTGG	ITCH	ENSG00000078747	0.1461697748634569	[6]	[6,5]	3	hSpCas9	positive selection	3846040
34440274	34440297	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCCTCCAGATATAGTAAGAGG	ITCH	ENSG00000078747	0.014298783336636128	[5]	[3,5]	0	hSpCas9	positive selection	3846041
34462123	34462146	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGGGAAATGAGATTCACAGTGG	ITCH	ENSG00000078747	-0.1251146026158869	[5]	[2,5]	-2	hSpCas9	positive selection	3846042
34438586	34438609	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTGGTCGTGAAGGTCTTGGAGG	ITCH	ENSG00000078747	0.12462249200326196	[5]	[4,6]	3	hSpCas9	positive selection	3846043
34424504	34424527	20	+	26780180	A375	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	1.0401939143597	[]	[]	5	hSpCas9	negative selection	3952061
34413804	34413827	20	+	26780180	A375	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.57394639273371	[]	[]	1	hSpCas9	negative selection	3952062
34413837	34413860	20	+	26780180	A375	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	1.94112240647033	[]	[]	9	hSpCas9	negative selection	3952063
34424479	34424502	20	+	26780180	A375	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.737559288376144	[]	[]	2	hSpCas9	negative selection	3952064
34413750	34413773	20	+	26780180	A375	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	1.09156186125584	[]	[]	5	hSpCas9	negative selection	3952065
34413853	34413876	20	-	26780180	A375	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	1.63270378923659	[]	[]	8	hSpCas9	negative selection	3952066
34424504	34424527	20	+	26780180	HT29	viability (GeCKOv2 library)	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.265628864206499	[]	[]	0	hSpCas9	negative selection	4060027
34413804	34413827	20	+	26780180	HT29	viability (GeCKOv2 library)	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	1.10252123801609	[]	[]	5	hSpCas9	negative selection	4060028
34413837	34413860	20	+	26780180	HT29	viability (GeCKOv2 library)	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.496714435257186	[]	[]	1	hSpCas9	negative selection	4060029
34424479	34424502	20	+	26780180	HT29	viability (GeCKOv2 library)	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.519259977147773	[]	[]	1	hSpCas9	negative selection	4060030
34413750	34413773	20	+	26780180	HT29	viability (GeCKOv2 library)	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.445334999160066	[]	[]	1	hSpCas9	negative selection	4060031
34413853	34413876	20	-	26780180	HT29	viability (GeCKOv2 library)	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	0.201718770787607	[]	[]	0	hSpCas9	negative selection	4060032
34412525	34412548	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAAAATGTAATTTACTCACAGG	ITCH	ENSG00000078747	-0.021713910183134302	[4]	[2,2]	0	hSpCas9	positive selection	4145402
34412532	34412555	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAAATTACATTTTCGTGTGTGG	ITCH	ENSG00000078747	-0.11399947938430854	[4]	[1,2]	-3	hSpCas9	positive selection	4145403
34413750	34413773	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.1663266334187108	[4]	[3,3]	4	hSpCas9	positive selection	4145404
34412525	34412548	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAAAATGTAATTTACTCACAGG	ITCH	ENSG00000078747	-0.3816712269270787	[3]	[0,0,2,0]	-5	hSpCas9	positive selection	4209424
34412532	34412555	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAAATTACATTTTCGTGTGTGG	ITCH	ENSG00000078747	-0.46681495489261393	[3]	[0,0,1,0]	-6	hSpCas9	positive selection	4209425
34413750	34413773	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.2761998132850602	[4]	[0,5,4,0]	2	hSpCas9	positive selection	4209426
34413750	34413773	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.43462585305028145	[2]	[3,2]	8	hSpCas9	positive selection	4277382
34413837	34413860	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.014807305659565492	[3]	[2,2]	0	hSpCas9	positive selection	4277383
34424504	34424527	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.18043804011520753	[1]	[2,0]	-4	hSpCas9	positive selection	4277384
34424479	34424502	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.11063752885201827	[2]	[2,1]	2	hSpCas9	positive selection	4341638
34413853	34413876	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	0.014413332675140555	[4]	[3,2]	0	hSpCas9	positive selection	4341639
34413804	34413827	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.598229957116551	[2]	[3,3]	9	hSpCas9	positive selection	4341640
34438617	34438639	20	-	27760321	OCIAML3	viability	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.6436631324218997	[427,404]	[442,595]	7	hSpCas9	negative selection	4410459
34440301	34440323	20	-	27760321	OCIAML3	viability	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.7339744402336243	[217,175]	[243,268]	8	hSpCas9	negative selection	4410460
34442226	34442248	20	-	27760321	OCIAML3	viability	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	0.15355817689715162	[644,560]	[511,537]	1	hSpCas9	negative selection	4410461
34445292	34445314	20	+	27760321	OCIAML3	viability	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.13803177969843283	[29,446]	[224,214]	1	hSpCas9	negative selection	4410462
34445377	34445399	20	+	27760321	OCIAML3	viability	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	-0.1394749096635271	[372,287]	[258,198]	-1	hSpCas9	negative selection	4410463
34438617	34438639	20	-	27760321	OCIAML2	viability	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.19656257629780402	[427,404]	[291,510]	2	hSpCas9	negative selection	4493922
34440301	34440323	20	-	27760321	OCIAML2	viability	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.6791693715626446	[217,175]	[201,321]	8	hSpCas9	negative selection	4493923
34442226	34442248	20	-	27760321	OCIAML2	viability	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	0.09910389435917316	[644,560]	[509,535]	1	hSpCas9	negative selection	4493924
34445292	34445314	20	+	27760321	OCIAML2	viability	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.7044554784929566	[29,446]	[255,445]	8	hSpCas9	negative selection	4493925
34445377	34445399	20	+	27760321	OCIAML2	viability	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.54428377227374	[372,287]	[336,452]	7	hSpCas9	negative selection	4493926
34438617	34438639	20	-	27760321	MV411	viability	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	-0.4923675738127232	[427,404]	[167,236]	-3	hSpCas9	negative selection	4577385
34440301	34440323	20	-	27760321	MV411	viability	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	-1.1564430761969509	[217,175]	[59,54]	-6	hSpCas9	negative selection	4577386
34442226	34442248	20	-	27760321	MV411	viability	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	0.03914143337612197	[644,560]	[490,282]	0	hSpCas9	negative selection	4577387
34445292	34445314	20	+	27760321	MV411	viability	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	1.272327392359668	[29,446]	[285,592]	8	hSpCas9	negative selection	4577388
34445377	34445399	20	+	27760321	MV411	viability	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	1.1092004283966188	[372,287]	[552,337]	7	hSpCas9	negative selection	4577389
34438617	34438639	20	-	27760321	HL60	viability	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.4221832904556029	[427,404]	[434,478]	5	hSpCas9	negative selection	4660848
34440301	34440323	20	-	27760321	HL60	viability	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.16437754379510439	[217,175]	[240,113]	2	hSpCas9	negative selection	4660849
34442226	34442248	20	-	27760321	HL60	viability	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.5269565995909933	[644,560]	[374,304]	-5	hSpCas9	negative selection	4660850
34445292	34445314	20	+	27760321	HL60	viability	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.6133973075361946	[29,446]	[350,287]	7	hSpCas9	negative selection	4660851
34445377	34445399	20	+	27760321	HL60	viability	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	-0.05487130920869776	[372,287]	[158,362]	0	hSpCas9	negative selection	4660852
34438617	34438639	20	-	27760321	HT1080	viability	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.21877390296610696	[404,315]	[232,94]	1	hSpCas9	negative selection	4744311
34440301	34440323	20	-	27760321	HT1080	viability	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.21584259023537267	[175,137]	[75,68]	1	hSpCas9	negative selection	4744312
34442226	34442248	20	-	27760321	HT1080	viability	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.6763324472686174	[560,437]	[145,100]	-3	hSpCas9	negative selection	4744313
34445292	34445314	20	+	27760321	HT1080	viability	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	-1.351001353978391	[446,348]	[75,46]	-5	hSpCas9	negative selection	4744314
34445377	34445399	20	+	27760321	HT1080	viability	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.8662043755639027	[287,224]	[170,202]	5	hSpCas9	negative selection	4744315
34438617	34438639	20	-	27760321	HT29	viability after 7 days	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.36661709456056185	[404,315]	[826,443,554]	5	hSpCas9	negative selection	4827774
34440301	34440323	20	-	27760321	HT29	viability after 7 days	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.2140537318322474	[175,137]	[256,228,219]	3	hSpCas9	negative selection	4827775
34442226	34442248	20	-	27760321	HT29	viability after 7 days	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.5032421929066389	[560,437]	[535,556,282]	-6	hSpCas9	negative selection	4827776
34445292	34445314	20	+	27760321	HT29	viability after 7 days	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.3114801302098146	[446,348]	[713,519,679]	5	hSpCas9	negative selection	4827777
34445377	34445399	20	+	27760321	HT29	viability after 7 days	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.6126908126757508	[287,224]	[518,449,543]	8	hSpCas9	negative selection	4827778
34438617	34438639	20	-	27760321	HT29	viability after 25 days	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.7239394562485851	[404,315]	[785,581,663]	8	hSpCas9	negative selection	4911237
34440301	34440323	20	-	27760321	HT29	viability after 25 days	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.8655768271209144	[175,137]	[400,177,404]	8	hSpCas9	negative selection	4911238
34442226	34442248	20	-	27760321	HT29	viability after 25 days	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.4242305373253728	[560,437]	[421,538,301]	-4	hSpCas9	negative selection	4911239
34445292	34445314	20	+	27760321	HT29	viability after 25 days	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.6882685181490429	[446,348]	[707,725,768]	7	hSpCas9	negative selection	4911240
34445377	34445399	20	+	27760321	HT29	viability after 25 days	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.9676324133226657	[287,224]	[591,533,593]	9	hSpCas9	negative selection	4911241
34438617	34438639	20	-	27760321	HT29	viability after 22 days	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.7593327289517037	[404,315]	[845,505,760]	8	hSpCas9	negative selection	4994700
34440301	34440323	20	-	27760321	HT29	viability after 22 days	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.6997639936992228	[175,137]	[222,324,338]	7	hSpCas9	negative selection	4994701
34442226	34442248	20	-	27760321	HT29	viability after 22 days	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.45665555948600056	[560,437]	[460,403,395]	-4	hSpCas9	negative selection	4994702
34445292	34445314	20	+	27760321	HT29	viability after 22 days	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.9264271667770505	[446,348]	[873,710,1039]	9	hSpCas9	negative selection	4994703
34445377	34445399	20	+	27760321	HT29	viability after 22 days	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.8636237150583534	[287,224]	[619,413,582]	8	hSpCas9	negative selection	4994704
34438617	34438639	20	-	27760321	HT29	viability after 19 days	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	1.0180097187792645	[404,315]	[886,420,1187]	9	hSpCas9	negative selection	5078163
34440301	34440323	20	-	27760321	HT29	viability after 19 days	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.3427042621613594	[175,137]	[235,219,227]	3	hSpCas9	negative selection	5078164
34442226	34442248	20	-	27760321	HT29	viability after 19 days	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.6128146084391363	[560,437]	[463,481,190]	-5	hSpCas9	negative selection	5078165
34445292	34445314	20	+	27760321	HT29	viability after 19 days	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.40408194003627507	[446,348]	[781,483,560]	4	hSpCas9	negative selection	5078166
34445377	34445399	20	+	27760321	HT29	viability after 19 days	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.4397881031644199	[287,224]	[505,358,341]	4	hSpCas9	negative selection	5078167
34438617	34438639	20	-	27760321	HT29	viability after 16 days	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.40860765551739353	[404,315]	[582,478,549]	4	hSpCas9	negative selection	5161626
34440301	34440323	20	-	27760321	HT29	viability after 16 days	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.1576496874177653	[175,137]	[147,134,301]	1	hSpCas9	negative selection	5161627
34442226	34442248	20	-	27760321	HT29	viability after 16 days	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.27336753567328154	[560,437]	[523,573,291]	-3	hSpCas9	negative selection	5161628
34445292	34445314	20	+	27760321	HT29	viability after 16 days	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.43912018135402564	[446,348]	[888,565,383]	5	hSpCas9	negative selection	5161629
34445377	34445399	20	+	27760321	HT29	viability after 16 days	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	1.2789543946668347	[287,224]	[498,753,815]	9	hSpCas9	negative selection	5161630
34438617	34438639	20	-	27760321	HT29	viability after 13 days	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.13844621211676367	[404,315]	[587,372,421]	1	hSpCas9	negative selection	5245089
34440301	34440323	20	-	27760321	HT29	viability after 13 days	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	0.0818995617555014	[175,137]	[224,119,230]	1	hSpCas9	negative selection	5245090
34442226	34442248	20	-	27760321	HT29	viability after 13 days	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.5842329662918054	[560,437]	[283,544,333]	-6	hSpCas9	negative selection	5245091
34445292	34445314	20	+	27760321	HT29	viability after 13 days	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.36130755046505747	[446,348]	[458,716,602]	4	hSpCas9	negative selection	5245092
34445377	34445399	20	+	27760321	HT29	viability after 13 days	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.8837032329512304	[287,224]	[501,540,600]	9	hSpCas9	negative selection	5245093
34438617	34438639	20	-	27760321	HT29	viability after 10 days	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	0.04793709209668467	[404,315]	[551,489,356]	0	hSpCas9	negative selection	5328552
34440301	34440323	20	-	27760321	HT29	viability after 10 days	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	-0.037471599453671844	[175,137]	[225,212,135]	0	hSpCas9	negative selection	5328553
34442226	34442248	20	-	27760321	HT29	viability after 10 days	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.4643724079403176	[560,437]	[244,724,394]	-5	hSpCas9	negative selection	5328554
34445292	34445314	20	+	27760321	HT29	viability after 10 days	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.21162057849900476	[446,348]	[377,718,631]	3	hSpCas9	negative selection	5328555
34445377	34445399	20	+	27760321	HT29	viability after 10 days	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.7451860498561023	[287,224]	[456,623,531]	8	hSpCas9	negative selection	5328556
34438617	34438639	20	-	27760321	MOLM13	viability	TACAAACCTGGTCTACGTGGGG	ITCH	ENSG00000078747	1.2389978565232493	[427,404]	[975,196]	8	hSpCas9	negative selection	5412015
34440301	34440323	20	-	27760321	MOLM13	viability	TTACAGGATTTAATGGCCTAGG	ITCH	ENSG00000078747	-1.7607023172599847	[217,175]	[30,33]	-7	hSpCas9	negative selection	5412016
34442226	34442248	20	-	27760321	MOLM13	viability	ATAGTAAACTCGCCCGTGCTGG	ITCH	ENSG00000078747	-0.19285437309724884	[644,560]	[445,169]	-1	hSpCas9	negative selection	5412017
34445292	34445314	20	+	27760321	MOLM13	viability	AACGGCGGGTTGACAACATGGG	ITCH	ENSG00000078747	0.7030508580839161	[29,446]	[248,223]	5	hSpCas9	negative selection	5412018
34445377	34445399	20	+	27760321	MOLM13	viability	CGTCCGGAACTATGAACAATGG	ITCH	ENSG00000078747	0.00015717997764891356	[372,287]	[216,157]	0	hSpCas9	negative selection	5412019
34363342	34363365	20	+	27661255	K562	viability	GAGTCCCGGTAAACCCCCGTGGG	ITCH	ENSG00000078747	0.0019645775446252567	[942,913]	[788,703]	0	dCas9-KRAB	negative selection	5487321
34363743	34363766	20	+	27661255	K562	viability	GGGCGACGTGGCCCTGTGAGGGG	ITCH	ENSG00000078747	-0.2336334372295135	[668,715]	[511,433]	-6	dCas9-KRAB	negative selection	5487322
34413750	34413773	20	+	27260156	BXPC3	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.3163355600329646	[420]	[603,460,533,593]	7	hSpCas9	negative selection	5549842
34413837	34413860	20	+	27260156	BXPC3	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.2014886781619351	[567]	[585,568,689,929]	4	hSpCas9	negative selection	5549843
34424504	34424527	20	+	27260156	BXPC3	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.32240673190872515	[173]	[234,244,172,255]	7	hSpCas9	negative selection	5549844
34424479	34424502	20	+	27260156	BXPC3	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.26730034529307123	[234]	[314,203,275,401]	6	hSpCas9	negative selection	5614098
34413853	34413876	20	-	27260156	BXPC3	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.25559088416764264	[1272]	[958,987,1344,1198]	-5	hSpCas9	negative selection	5614099
34413804	34413827	20	+	27260156	BXPC3	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.23295401829560874	[436]	[434,583,659,466]	5	hSpCas9	negative selection	5614100
34413750	34413773	20	+	27260156	A673	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.12106414599067197	[420]	[557,547,542,549]	3	hSpCas9	negative selection	5671093
34413837	34413860	20	+	27260156	A673	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.09546901237580757	[567]	[810,615,671,832]	2	hSpCas9	negative selection	5671094
34424504	34424527	20	+	27260156	A673	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.24965764821405312	[173]	[243,207,237,306]	6	hSpCas9	negative selection	5671095
34424479	34424502	20	+	27260156	A673	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.30554093342152666	[234]	[414,356,299,328]	7	hSpCas9	negative selection	5735349
34413853	34413876	20	-	27260156	A673	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.18572499968216882	[1272]	[1288,1457,1173,1449]	-4	hSpCas9	negative selection	5735350
34413804	34413827	20	+	27260156	A673	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.005259565149414419	[436]	[515,494,489,608]	0	hSpCas9	negative selection	5735351
34413750	34413773	20	+	27260156	A375	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	-0.5022526720002647	[420]	[262,651,341,190]	-6	hSpCas9	negative selection	5792344
34413837	34413860	20	+	27260156	A375	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	-0.16219900361072603	[567]	[511,956,530,437]	-2	hSpCas9	negative selection	5792345
34424504	34424527	20	+	27260156	A375	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-1.0514901082043258	[173]	[34,211,50,107]	-8	hSpCas9	negative selection	5792346
34424479	34424502	20	+	27260156	A375	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-1.0976245904374125	[234]	[118,123,150,118]	-8	hSpCas9	negative selection	5856600
34413853	34413876	20	-	27260156	A375	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-1.1137556429939706	[1272]	[615,736,665,727]	-8	hSpCas9	negative selection	5856601
34413804	34413827	20	+	27260156	A375	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.4494417168110536	[436]	[654,833,821,514]	6	hSpCas9	negative selection	5856602
34413750	34413773	20	+	27260156	COLO741	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.2156738724272688	[420]	[616,714,545]	4	hSpCas9	negative selection	5913595
34413837	34413860	20	+	27260156	COLO741	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.24746408090325223	[567]	[1034,546,1003]	5	hSpCas9	negative selection	5913596
34424504	34424527	20	+	27260156	COLO741	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.31150921961110023	[173]	[288,246,290]	6	hSpCas9	negative selection	5913597
34424479	34424502	20	+	27260156	COLO741	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.18407969826119852	[234]	[334,196,265]	-4	hSpCas9	negative selection	5977851
34413853	34413876	20	-	27260156	COLO741	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.2266959044935164	[1272]	[1752,1263,1194]	-5	hSpCas9	negative selection	5977852
34413804	34413827	20	+	27260156	COLO741	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.2512125785197302	[436]	[781,695,533]	5	hSpCas9	negative selection	5977853
34413750	34413773	20	+	27260156	CAL120	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.5919340291250429	[420]	[1040,720,646]	8	hSpCas9	negative selection	6034846
34413837	34413860	20	+	27260156	CAL120	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.5055941004466888	[567]	[700,953,1303]	7	hSpCas9	negative selection	6034847
34424504	34424527	20	+	27260156	CAL120	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.48429381780449954	[173]	[485,252,198]	7	hSpCas9	negative selection	6034848
34424479	34424502	20	+	27260156	CAL120	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.7211350983476617	[234]	[534,438,479]	9	hSpCas9	negative selection	6099102
34413853	34413876	20	-	27260156	CAL120	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.308254844658187	[1272]	[1330,1497,1020]	-4	hSpCas9	negative selection	6099103
34413804	34413827	20	+	27260156	CAL120	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.9205185174624907	[436]	[984,965,1127]	9	hSpCas9	negative selection	6099104
34413750	34413773	20	+	27260156	CADOES1	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.5351684433570747	[420]	[606,481,595,584]	8	hSpCas9	negative selection	6156097
34413837	34413860	20	+	27260156	CADOES1	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.148956408740482	[567]	[410,724,663,541]	2	hSpCas9	negative selection	6156098
34424504	34424527	20	+	27260156	CADOES1	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.7679247456034669	[173]	[312,304,265,215]	9	hSpCas9	negative selection	6156099
34424479	34424502	20	+	27260156	CADOES1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.07134584485482098	[234]	[167,287,203,259]	1	hSpCas9	negative selection	6220353
34413853	34413876	20	-	27260156	CADOES1	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.23409807550970774	[1272]	[920,1204,923,975]	-4	hSpCas9	negative selection	6220354
34413804	34413827	20	+	27260156	CADOES1	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.5475911265335479	[436]	[521,563,475,822]	8	hSpCas9	negative selection	6220355
34413750	34413773	20	+	27260156	EWS502	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.390048568796192	[420]	[360,658,701,642]	6	hSpCas9	negative selection	6277348
34413837	34413860	20	+	27260156	EWS502	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.22998683657794217	[567]	[758,714,739,590]	4	hSpCas9	negative selection	6277349
34424504	34424527	20	+	27260156	EWS502	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.6308234403109185	[173]	[288,318,292,233]	9	hSpCas9	negative selection	6277350
34424479	34424502	20	+	27260156	EWS502	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.2686351080981608	[234]	[237,319,324,323]	5	hSpCas9	negative selection	6341604
34413853	34413876	20	-	27260156	EWS502	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.2115332941396404	[1272]	[898,1318,1250,1214]	-4	hSpCas9	negative selection	6341605
34413804	34413827	20	+	27260156	EWS502	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.47910530129954315	[436]	[712,506,622,738]	8	hSpCas9	negative selection	6341606
34413750	34413773	20	+	27260156	EW8	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.17331609548350432	[420]	[570,258,365,364]	3	hSpCas9	negative selection	6398599
34413837	34413860	20	+	27260156	EW8	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.39832123526238117	[567]	[680,610,662,468]	7	hSpCas9	negative selection	6398600
34424504	34424527	20	+	27260156	EW8	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.775673860687993	[173]	[454,246,157,142]	9	hSpCas9	negative selection	6398601
34424479	34424502	20	+	27260156	EW8	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.3337418863487661	[234]	[233,193,271,252]	6	hSpCas9	negative selection	6462855
34413853	34413876	20	-	27260156	EW8	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.2643966489564258	[1272]	[844,877,802,914]	-5	hSpCas9	negative selection	6462856
34413804	34413827	20	+	27260156	EW8	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.06260761352554887	[436]	[344,409,410,302]	1	hSpCas9	negative selection	6462857
34413750	34413773	20	+	27260156	CORL105	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.4515802439939858	[420]	[494,745,762,697]	8	hSpCas9	negative selection	6519850
34413837	34413860	20	+	27260156	CORL105	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.3055128913666737	[567]	[758,710,895,931]	5	hSpCas9	negative selection	6519851
34424504	34424527	20	+	27260156	CORL105	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	1.0185341224409186	[173]	[396,373,421,458]	9	hSpCas9	negative selection	6519852
34424479	34424502	20	+	27260156	CORL105	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.1258785479469342	[234]	[344,273,388,208]	2	hSpCas9	negative selection	6584106
34413853	34413876	20	-	27260156	CORL105	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.03640624746662113	[1272]	[1394,1464,1467,1483]	0	hSpCas9	negative selection	6584107
34413804	34413827	20	+	27260156	CORL105	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.1678577087567939	[436]	[711,551,572,466]	3	hSpCas9	negative selection	6584108
34413750	34413773	20	+	27260156	HS294T	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.2822940301798418	[420]	[227,127,234,199]	4	hSpCas9	negative selection	6641101
34413837	34413860	20	+	27260156	HS294T	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.49771755476980495	[567]	[221,181,389,487]	6	hSpCas9	negative selection	6641102
34424504	34424527	20	+	27260156	HS294T	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.6551499881840429	[173]	[94,110,58,169]	8	hSpCas9	negative selection	6641103
34424479	34424502	20	+	27260156	HS294T	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.44683940356231444	[234]	[51,63,84,66]	-6	hSpCas9	negative selection	6705357
34413853	34413876	20	-	27260156	HS294T	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.43637530202659214	[1272]	[271,335,439,425]	-6	hSpCas9	negative selection	6705358
34413804	34413827	20	+	27260156	HS294T	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.5945522239090995	[436]	[249,240,257,274]	7	hSpCas9	negative selection	6705359
34413750	34413773	20	+	27260156	HCC44	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.4460818028453625	[420]	[833,428,933,494]	7	hSpCas9	negative selection	6762352
34413837	34413860	20	+	27260156	HCC44	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	-0.07880871179620838	[567]	[686,347,797,669]	-1	hSpCas9	negative selection	6762353
34424504	34424527	20	+	27260156	HCC44	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.3850948273604813	[173]	[228,229,279,290]	6	hSpCas9	negative selection	6762354
34424479	34424502	20	+	27260156	HCC44	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.1500657140606929	[234]	[258,182,256,268]	-2	hSpCas9	negative selection	6826608
34413853	34413876	20	-	27260156	HCC44	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.6369235007335495	[1272]	[755,762,961,1218]	-7	hSpCas9	negative selection	6826609
34413804	34413827	20	+	27260156	HCC44	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.06019010231658498	[436]	[400,393,554,713]	0	hSpCas9	negative selection	6826610
34413750	34413773	20	+	27260156	G402	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	1.0677281099995237	[420]	[1004,935,1638,721]	9	hSpCas9	negative selection	6883603
34413837	34413860	20	+	27260156	G402	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.43063718857718525	[567]	[984,1083,766,913]	5	hSpCas9	negative selection	6883604
34424504	34424527	20	+	27260156	G402	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	1.7018504004362422	[173]	[287,651,1159,603]	9	hSpCas9	negative selection	6883605
34424479	34424502	20	+	27260156	G402	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.7826241635073468	[234]	[295,699,767,204]	8	hSpCas9	negative selection	6947859
34413853	34413876	20	-	27260156	G402	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.13625230188507897	[1272]	[1691,1375,1460,1168]	-2	hSpCas9	negative selection	6947860
34413804	34413827	20	+	27260156	G402	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.41785391731732235	[436]	[373,1306,515,638]	5	hSpCas9	negative selection	6947861
34413750	34413773	20	+	27260156	L33	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.5473466899266608	[420]	[691,234,395,563]	9	hSpCas9	negative selection	7004854
34413837	34413860	20	+	27260156	L33	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.32559683498723313	[567]	[834,268,425,674]	7	hSpCas9	negative selection	7004855
34424504	34424527	20	+	27260156	L33	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.5086974324378172	[173]	[274,91,153,244]	8	hSpCas9	negative selection	7004856
34424479	34424502	20	+	27260156	L33	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.08836960025865148	[234]	[272,65,153,318]	2	hSpCas9	negative selection	7069110
34413853	34413876	20	-	27260156	L33	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.4213592006453364	[1272]	[1034,377,600,886]	-7	hSpCas9	negative selection	7069111
34413804	34413827	20	+	27260156	L33	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.115993369706634	[436]	[451,186,362,409]	2	hSpCas9	negative selection	7069112
34413750	34413773	20	+	27260156	K562	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.29266684639298535	[420]	[569,360,578,336]	3	hSpCas9	negative selection	7126105
34413837	34413860	20	+	27260156	K562	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.28329155444823184	[567]	[874,511,502,580]	3	hSpCas9	negative selection	7126106
34424504	34424527	20	+	27260156	K562	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.28046028169076065	[173]	[190,97,173,56]	-3	hSpCas9	negative selection	7126107
34424479	34424502	20	+	27260156	K562	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.19481653294843837	[234]	[141,381,73,141]	-2	hSpCas9	negative selection	7190361
34413853	34413876	20	-	27260156	K562	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.44792035828016896	[1272]	[905,906,756,757]	-5	hSpCas9	negative selection	7190362
34413804	34413827	20	+	27260156	K562	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.6023885255777058	[436]	[543,649,850,336]	7	hSpCas9	negative selection	7190363
34413750	34413773	20	+	27260156	HT29	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.3317738511797891	[420]	[570,722,707,578]	6	hSpCas9	negative selection	7247356
34413837	34413860	20	+	27260156	HT29	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.18640054694304115	[567]	[788,867,823,676]	3	hSpCas9	negative selection	7247357
34424504	34424527	20	+	27260156	HT29	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.509374626411441	[173]	[357,381,311,176]	8	hSpCas9	negative selection	7247358
34424479	34424502	20	+	27260156	HT29	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.2911183712244879	[234]	[299,415,452,241]	6	hSpCas9	negative selection	7311612
34413853	34413876	20	-	27260156	HT29	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.22690428236737525	[1272]	[1627,1150,1543,1004]	-4	hSpCas9	negative selection	7311613
34413804	34413827	20	+	27260156	HT29	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.03795639956478403	[436]	[644,588,436,520]	0	hSpCas9	negative selection	7311614
34413750	34413773	20	+	27260156	MHHES1	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.34576532413630334	[420]	[754,586,562,525]	6	hSpCas9	negative selection	7368607
34413837	34413860	20	+	27260156	MHHES1	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.48418561061432175	[567]	[1032,829,1133,634]	8	hSpCas9	negative selection	7368608
34424504	34424527	20	+	27260156	MHHES1	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.5185286519976086	[173]	[187,436,201,290]	8	hSpCas9	negative selection	7368609
34424479	34424502	20	+	27260156	MHHES1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.04330311054065561	[234]	[246,291,143,323]	-1	hSpCas9	negative selection	7432863
34413853	34413876	20	-	27260156	MHHES1	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.22138309404673495	[1272]	[1490,1059,1001,1326]	-4	hSpCas9	negative selection	7432864
34413804	34413827	20	+	27260156	MHHES1	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.49519564073189515	[436]	[1141,670,614,441]	8	hSpCas9	negative selection	7432865
34413750	34413773	20	+	27260156	MEWO	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.34847827798966496	[420]	[729,421,396]	7	hSpCas9	negative selection	7489858
34413837	34413860	20	+	27260156	MEWO	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.37443249318076743	[567]	[842,547,705]	7	hSpCas9	negative selection	7489859
34424504	34424527	20	+	27260156	MEWO	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.34205323030256274	[173]	[185,214,213]	7	hSpCas9	negative selection	7489860
34424479	34424502	20	+	27260156	MEWO	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.5246665691841885	[234]	[395,363,203]	9	hSpCas9	negative selection	7554114
34413853	34413876	20	-	27260156	MEWO	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.18118992423945612	[1272]	[1328,836,1039]	-4	hSpCas9	negative selection	7554115
34413804	34413827	20	+	27260156	MEWO	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.015180517129369533	[436]	[459,305,482]	0	hSpCas9	negative selection	7554116
34413750	34413773	20	+	27260156	LNCAPCLONEFGC	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.060372196870085784	[420]	[370,359,421,443]	0	hSpCas9	negative selection	7611109
34413837	34413860	20	+	27260156	LNCAPCLONEFGC	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.31018635239709913	[567]	[560,579,747,683]	5	hSpCas9	negative selection	7611110
34424504	34424527	20	+	27260156	LNCAPCLONEFGC	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.8128831614509522	[173]	[270,223,404,229]	9	hSpCas9	negative selection	7611111
34424479	34424502	20	+	27260156	LNCAPCLONEFGC	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.11316350012638277	[234]	[181,247,232,257]	1	hSpCas9	negative selection	7675365
34413853	34413876	20	-	27260156	LNCAPCLONEFGC	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.5503938731080449	[1272]	[519,905,945,797]	-7	hSpCas9	negative selection	7675366
34413804	34413827	20	+	27260156	LNCAPCLONEFGC	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.27908940354345885	[436]	[413,476,644,410]	4	hSpCas9	negative selection	7675367
34413750	34413773	20	+	27260156	PANC0327	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.931036511817362	[420]	[764,543,1159,409]	9	hSpCas9	negative selection	7732360
34413837	34413860	20	+	27260156	PANC0327	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.4893868201861441	[567]	[763,481,822,797]	7	hSpCas9	negative selection	7732361
34424504	34424527	20	+	27260156	PANC0327	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.2837782683666663	[173]	[232,289,87,131]	4	hSpCas9	negative selection	7732362
34424479	34424502	20	+	27260156	PANC0327	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.7742382162086909	[234]	[206,294,117,802]	9	hSpCas9	negative selection	7796616
34413853	34413876	20	-	27260156	PANC0327	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.35629675819401085	[1272]	[1177,460,1007,964]	-5	hSpCas9	negative selection	7796617
34413804	34413827	20	+	27260156	PANC0327	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.3296459856334608	[436]	[649,202,415,731]	5	hSpCas9	negative selection	7796618
34413750	34413773	20	+	27260156	NCIH2009	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.31403342139318036	[420]	[904,886,431]	4	hSpCas9	negative selection	7853611
34413837	34413860	20	+	27260156	NCIH2009	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.3902000281211381	[567]	[1378,785,1024]	5	hSpCas9	negative selection	7853612
34424504	34424527	20	+	27260156	NCIH2009	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	1.0467184628691524	[173]	[462,393,642]	9	hSpCas9	negative selection	7853613
34424479	34424502	20	+	27260156	NCIH2009	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.6121329188044107	[234]	[311,173,177]	-6	hSpCas9	negative selection	7917867
34413853	34413876	20	-	27260156	NCIH2009	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.8379700512305323	[1272]	[856,1270,822]	-7	hSpCas9	negative selection	7917868
34413804	34413827	20	+	27260156	NCIH2009	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.4125746861347089	[436]	[994,631,848]	5	hSpCas9	negative selection	7917869
34413750	34413773	20	+	27260156	NCIH1373	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.1390769171501039	[420]	[544,530,432,150]	1	hSpCas9	negative selection	7974862
34413837	34413860	20	+	27260156	NCIH1373	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	-0.31848943498637766	[567]	[574,604,572,70]	-3	hSpCas9	negative selection	7974863
34424504	34424527	20	+	27260156	NCIH1373	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.9624222329295389	[173]	[869,289,318,28]	8	hSpCas9	negative selection	7974864
34424479	34424502	20	+	27260156	NCIH1373	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-1.2775702615552107	[234]	[116,99,129,22]	-8	hSpCas9	negative selection	8039118
34413853	34413876	20	-	27260156	NCIH1373	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.25550729343195866	[1272]	[1094,1204,1145,346]	-3	hSpCas9	negative selection	8039119
34413804	34413827	20	+	27260156	NCIH1373	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.7368037723587673	[436]	[1046,813,740,180]	7	hSpCas9	negative selection	8039120
34413750	34413773	20	+	27260156	PATU8902	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.779931166338613	[420]	[747,985,650,1827]	8	hSpCas9	negative selection	8096113
34413837	34413860	20	+	27260156	PATU8902	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.6631887603068217	[567]	[1385,1699,978,972]	7	hSpCas9	negative selection	8096114
34424504	34424527	20	+	27260156	PATU8902	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.8238335204462011	[173]	[795,337,334,239]	8	hSpCas9	negative selection	8096115
34424479	34424502	20	+	27260156	PATU8902	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.42226521432703945	[234]	[593,355,481,286]	4	hSpCas9	negative selection	8160369
34413853	34413876	20	-	27260156	PATU8902	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.13946320721444594	[1272]	[2138,1731,946,1794]	-1	hSpCas9	negative selection	8160370
34413804	34413827	20	+	27260156	PATU8902	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.753237266152944	[436]	[879,1218,750,1358]	7	hSpCas9	negative selection	8160371
34413750	34413773	20	+	27260156	PANC1	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.22423412435367765	[420]	[378,518,547,281]	3	hSpCas9	negative selection	8217364
34413837	34413860	20	+	27260156	PANC1	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.249387118727173	[567]	[841,625,474,399]	4	hSpCas9	negative selection	8217365
34424504	34424527	20	+	27260156	PANC1	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.644204108445252	[173]	[258,290,203,193]	9	hSpCas9	negative selection	8217366
34424479	34424502	20	+	27260156	PANC1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.36992065405671315	[234]	[203,481,245,168]	6	hSpCas9	negative selection	8281620
34413853	34413876	20	-	27260156	PANC1	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.04158801574737758	[1272]	[1023,1621,802,919]	0	hSpCas9	negative selection	8281621
34413804	34413827	20	+	27260156	PANC1	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.37733435940778437	[436]	[474,605,490,407]	6	hSpCas9	negative selection	8281622
34413750	34413773	20	+	27260156	PANC0813	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.1998019650554778	[420]	[635,531,486,618]	3	hSpCas9	negative selection	8338615
34413837	34413860	20	+	27260156	PANC0813	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.11818333185815	[567]	[1017,634,685,590]	2	hSpCas9	negative selection	8338616
34424504	34424527	20	+	27260156	PANC0813	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.672419043863242	[173]	[325,372,239,360]	9	hSpCas9	negative selection	8338617
34424479	34424502	20	+	27260156	PANC0813	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.34356171797625734	[234]	[256,184,222,208]	-5	hSpCas9	negative selection	8402871
34413853	34413876	20	-	27260156	PANC0813	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.5736312289751976	[1272]	[1223,1013,921,883]	-7	hSpCas9	negative selection	8402872
34413804	34413827	20	+	27260156	PANC0813	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.2885227733656004	[436]	[746,726,521,526]	4	hSpCas9	negative selection	8402873
34413750	34413773	20	+	27260156	RDES	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.2347575378348397	[420]	[578,372,698,641]	4	hSpCas9	negative selection	8459866
34413837	34413860	20	+	27260156	RDES	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.1542884998530265	[567]	[584,691,748,924]	2	hSpCas9	negative selection	8459867
34424504	34424527	20	+	27260156	RDES	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.3173259869303928	[173]	[186,256,267,298]	5	hSpCas9	negative selection	8459868
34424479	34424502	20	+	27260156	RDES	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.14221944355681282	[234]	[249,315,375,244]	2	hSpCas9	negative selection	8524122
34413853	34413876	20	-	27260156	RDES	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.5047499695641319	[1272]	[895,974,1064,1223]	-7	hSpCas9	negative selection	8524123
34413804	34413827	20	+	27260156	RDES	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.2826069051872394	[436]	[471,665,675,644]	4	hSpCas9	negative selection	8524124
34413750	34413773	20	+	27260156	PC3	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.06246835951866053	[420]	[267,357,733,550]	1	hSpCas9	negative selection	8581117
34413837	34413860	20	+	27260156	PC3	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	-0.2630662796817741	[567]	[282,354,917,554]	-5	hSpCas9	negative selection	8581118
34424504	34424527	20	+	27260156	PC3	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.4736801520047367	[173]	[106,134,684,258]	8	hSpCas9	negative selection	8581119
34424479	34424502	20	+	27260156	PC3	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.39295073274116976	[234]	[286,280,422,248]	8	hSpCas9	negative selection	8645373
34413853	34413876	20	-	27260156	PC3	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.7260528255568013	[1272]	[563,712,1084,838]	-9	hSpCas9	negative selection	8645374
34413804	34413827	20	+	27260156	PC3	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	-0.07920252865176249	[436]	[345,236,716,457]	-2	hSpCas9	negative selection	8645375
34413750	34413773	20	+	27260156	PATU8988T	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.3642812405642325	[420]	[475,619,514,489]	6	hSpCas9	negative selection	8702368
34413837	34413860	20	+	27260156	PATU8988T	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.2915406711203452	[567]	[693,781,501,725]	5	hSpCas9	negative selection	8702369
34424504	34424527	20	+	27260156	PATU8988T	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.7603781429800687	[173]	[313,288,193,348]	9	hSpCas9	negative selection	8702370
34424479	34424502	20	+	27260156	PATU8988T	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.5387555457851056	[234]	[476,318,148,379]	8	hSpCas9	negative selection	8766624
34413853	34413876	20	-	27260156	PATU8988T	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.24104818251935134	[1272]	[776,1253,1071,1082]	-4	hSpCas9	negative selection	8766625
34413804	34413827	20	+	27260156	PATU8988T	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.08666780107134993	[436]	[456,544,440,351]	1	hSpCas9	negative selection	8766626
34413750	34413773	20	+	27260156	T47D	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.10466502606246819	[420]	[564,447,566,535]	2	hSpCas9	negative selection	8823619
34413837	34413860	20	+	27260156	T47D	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.17315023859741557	[567]	[859,659,693,779]	3	hSpCas9	negative selection	8823620
34424504	34424527	20	+	27260156	T47D	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.37656809215637876	[173]	[300,267,199,284]	7	hSpCas9	negative selection	8823621
34424479	34424502	20	+	27260156	T47D	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.10509729104144372	[234]	[325,306,279,262]	2	hSpCas9	negative selection	8887875
34413853	34413876	20	-	27260156	T47D	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.5433700536840487	[1272]	[1014,982,1004,1071]	-8	hSpCas9	negative selection	8887876
34413804	34413827	20	+	27260156	T47D	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.4004211362961326	[436]	[637,629,787,631]	8	hSpCas9	negative selection	8887877
34413750	34413773	20	+	27260156	SU8686	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.5557501415640629	[420]	[536,438,557,1009]	8	hSpCas9	negative selection	8944870
34413837	34413860	20	+	27260156	SU8686	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.4453713290876665	[567]	[660,717,706,1035]	7	hSpCas9	negative selection	8944871
34424504	34424527	20	+	27260156	SU8686	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.8035611092014375	[173]	[291,281,290,347]	9	hSpCas9	negative selection	8944872
34424479	34424502	20	+	27260156	SU8686	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.1718304769428154	[234]	[138,207,215,282]	-3	hSpCas9	negative selection	9009126
34413853	34413876	20	-	27260156	SU8686	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.3589908277880154	[1272]	[1033,726,1032,1198]	-5	hSpCas9	negative selection	9009127
34413804	34413827	20	+	27260156	SU8686	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.27813940636584744	[436]	[462,442,582,647]	5	hSpCas9	negative selection	9009128
34413750	34413773	20	+	27260156	SKES1	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.2563987888527566	[420]	[597,653,345,443]	5	hSpCas9	negative selection	9066121
34413837	34413860	20	+	27260156	SKES1	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.39979614846134737	[567]	[902,772,741,605]	7	hSpCas9	negative selection	9066122
34424504	34424527	20	+	27260156	SKES1	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.41426157416893616	[173]	[233,331,206,169]	8	hSpCas9	negative selection	9066123
34424479	34424502	20	+	27260156	SKES1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.3750203029105348	[234]	[316,405,260,249]	7	hSpCas9	negative selection	9130377
34413853	34413876	20	-	27260156	SKES1	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.28060464568104093	[1272]	[1341,1223,889,807]	-6	hSpCas9	negative selection	9130378
34413804	34413827	20	+	27260156	SKES1	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.2553867719751769	[436]	[644,427,567,448]	5	hSpCas9	negative selection	9130379
34413750	34413773	20	+	27260156	TOV112D	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.2968436319067985	[420]	[543,842,311,455]	5	hSpCas9	negative selection	9187372
34413837	34413860	20	+	27260156	TOV112D	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.20856441435292583	[567]	[628,729,777,510]	4	hSpCas9	negative selection	9187373
34424504	34424527	20	+	27260156	TOV112D	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.4776476909193996	[173]	[240,289,288,163]	8	hSpCas9	negative selection	9187374
34424479	34424502	20	+	27260156	TOV112D	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.5393921639922119	[234]	[211,579,269,352]	8	hSpCas9	negative selection	9251628
34413853	34413876	20	-	27260156	TOV112D	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	0.15020728264358407	[1272]	[1346,1918,1293,1220]	3	hSpCas9	negative selection	9251629
34413804	34413827	20	+	27260156	TOV112D	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.24422893370795357	[436]	[532,691,527,367]	5	hSpCas9	negative selection	9251630
34413750	34413773	20	+	27260156	TC71	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.2846976575834873	[420]	[612,493,498,595]	7	hSpCas9	negative selection	9308623
34413837	34413860	20	+	27260156	TC71	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.07019153934444639	[567]	[499,608,740,710]	1	hSpCas9	negative selection	9308624
34424504	34424527	20	+	27260156	TC71	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.23930527241342237	[173]	[188,243,218,229]	6	hSpCas9	negative selection	9308625
34424479	34424502	20	+	27260156	TC71	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.19129892188418196	[234]	[307,284,255,302]	5	hSpCas9	negative selection	9372879
34413853	34413876	20	-	27260156	TC71	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.1690944563825525	[1272]	[1352,1274,1044,1181]	-4	hSpCas9	negative selection	9372880
34413804	34413827	20	+	27260156	TC71	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.09258237604590257	[436]	[393,563,400,653]	2	hSpCas9	negative selection	9372881
34413750	34413773	20	+	27260156	TC32	viability	GTAGTTGTGACTTTGCAGCTTGG	ITCH	ENSG00000078747	0.18105239300480397	[420]	[428,410,539,415]	3	hSpCas9	negative selection	9429874
34413837	34413860	20	+	27260156	TC32	viability	GAGTCTGAAGTTGTTACCAATGG	ITCH	ENSG00000078747	0.14634381253660328	[567]	[632,380,746,672]	2	hSpCas9	negative selection	9429875
34424504	34424527	20	+	27260156	TC32	viability	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.7925304004408226	[173]	[157,271,479,258]	9	hSpCas9	negative selection	9429876
34424479	34424502	20	+	27260156	TC32	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.31509604442147165	[234]	[146,148,179,241]	-5	hSpCas9	negative selection	9494130
34413853	34413876	20	-	27260156	TC32	viability	TGAACATGTAGTTTCACCATTGG	ITCH	ENSG00000078747	-0.18612456194773008	[1272]	[905,920,1201,1214]	-3	hSpCas9	negative selection	9494131
34413804	34413827	20	+	27260156	TC32	viability	GACTTGTCAATTTGTCTTGATGG	ITCH	ENSG00000078747	0.3428311652753305	[436]	[528,287,815,561]	6	hSpCas9	negative selection	9494132
34393803	34393826	20	+	27869803	HPAFII	viability after 27 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	1.520763461901828	[174]	[143,363,NaN]	9	hSpCas9	negative selection	9577161
34424504	34424527	20	+	27869803	HPAFII	viability after 27 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.8791986265410812	[633]	[587,633,NaN]	7	hSpCas9	negative selection	9577162
34440332	34440355	20	-	27869803	HPAFII	viability after 27 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	1.7982508620714688	[263]	[365,579,NaN]	9	hSpCas9	negative selection	9577163
34445376	34445399	20	-	27869803	HPAFII	viability after 27 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	0.6183576915379206	[351]	[210,344,NaN]	5	hSpCas9	negative selection	9577164
34470105	34470128	20	-	27869803	HPAFII	viability after 27 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.15070267677697913	[461]	[267,270,NaN]	1	hSpCas9	negative selection	9577165
34479723	34479746	20	-	27869803	HPAFII	viability after 27 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	2.4990067989262514	[158]	[165,727,NaN]	9	hSpCas9	negative selection	9577166
34393803	34393826	20	+	27869803	HPAFII	viability after 15 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	0.018381508376426547	[174]	[253,150,NaN]	0	hSpCas9	negative selection	9659610
34424504	34424527	20	+	27869803	HPAFII	viability after 15 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.5096773979592895	[633]	[1151,856,NaN]	6	hSpCas9	negative selection	9659611
34440332	34440355	20	-	27869803	HPAFII	viability after 15 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.731377189669438	[263]	[676,342,NaN]	7	hSpCas9	negative selection	9659612
34445376	34445399	20	-	27869803	HPAFII	viability after 15 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	1.014893436567407	[351]	[880,691,NaN]	9	hSpCas9	negative selection	9659613
34470105	34470128	20	-	27869803	HPAFII	viability after 15 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.026736828147098213	[461]	[746,325,NaN]	0	hSpCas9	negative selection	9659614
34479723	34479746	20	-	27869803	HPAFII	viability after 15 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	1.2022998706042478	[158]	[325,434,NaN]	9	hSpCas9	negative selection	9659615
34393803	34393826	20	+	27869803	ASPC1	viability after 36 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.1750648862471779	[560]	[116,271,132]	-2	hSpCas9	negative selection	9742059
34424504	34424527	20	+	27869803	ASPC1	viability after 36 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	2.03856174922509	[1542]	[1428,2380,2605]	9	hSpCas9	negative selection	9742060
34440332	34440355	20	-	27869803	ASPC1	viability after 36 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	0.11067493383620416	[692]	[270,402,138]	1	hSpCas9	negative selection	9742061
34445376	34445399	20	-	27869803	ASPC1	viability after 36 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	1.783355458520938	[1156]	[1416,1442,1314]	9	hSpCas9	negative selection	9742062
34470105	34470128	20	-	27869803	ASPC1	viability after 36 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	1.3086606850567915	[1047]	[1159,843,767]	9	hSpCas9	negative selection	9742063
34479723	34479746	20	-	27869803	ASPC1	viability after 36 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	2.8746394439961196	[431]	[467,1406,1302]	9	hSpCas9	negative selection	9742064
34393803	34393826	20	+	27869803	PATU8988S	viability after 35 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	0.03486864383305227	[504]	[148,267,NaN]	0	hSpCas9	negative selection	9824508
34424504	34424527	20	+	27869803	PATU8988S	viability after 35 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	0.04662679847243756	[1269]	[437,618,NaN]	0	hSpCas9	negative selection	9824509
34440332	34440355	20	-	27869803	PATU8988S	viability after 35 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.8943684479864993	[611]	[177,86,NaN]	-7	hSpCas9	negative selection	9824510
34445376	34445399	20	-	27869803	PATU8988S	viability after 35 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.47652072214756	[958]	[317,236,NaN]	-5	hSpCas9	negative selection	9824511
34470105	34470128	20	-	27869803	PATU8988S	viability after 35 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.2983167517916484	[753]	[223,269,NaN]	-3	hSpCas9	negative selection	9824512
34479723	34479746	20	-	27869803	PATU8988S	viability after 35 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.6625657517314413	[384]	[79,115,NaN]	-6	hSpCas9	negative selection	9824513
34393803	34393826	20	+	27869803	PATU8988S	viability after 31 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	-0.043978523209439985	[504]	[193,196,NaN]	0	hSpCas9	negative selection	9906957
34424504	34424527	20	+	27869803	PATU8988S	viability after 31 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	-0.07059804838109196	[1269]	[384,605,NaN]	-1	hSpCas9	negative selection	9906958
34440332	34440355	20	-	27869803	PATU8988S	viability after 31 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	-0.6261050156842616	[611]	[125,198,NaN]	-6	hSpCas9	negative selection	9906959
34445376	34445399	20	-	27869803	PATU8988S	viability after 31 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	-0.9425911304698005	[958]	[194,203,NaN]	-7	hSpCas9	negative selection	9906960
34470105	34470128	20	-	27869803	PATU8988S	viability after 31 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	-0.43681576651634485	[753]	[178,276,NaN]	-5	hSpCas9	negative selection	9906961
34479723	34479746	20	-	27869803	PATU8988S	viability after 31 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	-0.34441196010786734	[384]	[90,158,NaN]	-4	hSpCas9	negative selection	9906962
34393803	34393826	20	+	27869803	HPAFII	viability after 35 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	1.6552644295159413	[174]	[144,429,NaN]	9	hSpCas9	negative selection	9989406
34424504	34424527	20	+	27869803	HPAFII	viability after 35 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	1.3907756499951158	[633]	[787,901,NaN]	8	hSpCas9	negative selection	9989407
34440332	34440355	20	-	27869803	HPAFII	viability after 35 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	1.9640702525916705	[263]	[353,709,NaN]	9	hSpCas9	negative selection	9989408
34445376	34445399	20	-	27869803	HPAFII	viability after 35 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	1.176542830801016	[351]	[216,611,NaN]	7	hSpCas9	negative selection	9989409
34470105	34470128	20	-	27869803	HPAFII	viability after 35 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.8476095340431257	[461]	[418,422,NaN]	5	hSpCas9	negative selection	9989410
34479723	34479746	20	-	27869803	HPAFII	viability after 35 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	3.565406356851581	[158]	[300,1686,NaN]	9	hSpCas9	negative selection	9989411
34393803	34393826	20	+	27869803	HPAFII	viability after 31 days	ATTGGTGGTATGTCTGACAGTGG	ITCH	ENSG00000078747	0.9973955996778858	[174]	[85,315,NaN]	7	hSpCas9	negative selection	10071855
34424504	34424527	20	+	27869803	HPAFII	viability after 31 days	CCAGATCCAAGGATGAAACAAGG	ITCH	ENSG00000078747	1.206822751444429	[633]	[872,764,NaN]	8	hSpCas9	negative selection	10071856
34440332	34440355	20	-	27869803	HPAFII	viability after 31 days	AGTTACTCACCCAGGTGGCAAGG	ITCH	ENSG00000078747	1.7796483642920706	[263]	[367,661,NaN]	9	hSpCas9	negative selection	10071857
34445376	34445399	20	-	27869803	HPAFII	viability after 31 days	CCATTGTTCATAGTTCCGGACGG	ITCH	ENSG00000078747	1.086736769788025	[351]	[264,587,NaN]	7	hSpCas9	negative selection	10071858
34470105	34470128	20	-	27869803	HPAFII	viability after 31 days	TACTAACCTGACACCAGAACCGG	ITCH	ENSG00000078747	0.3285790476380849	[461]	[338,310,NaN]	2	hSpCas9	negative selection	10071859
34479723	34479746	20	-	27869803	HPAFII	viability after 31 days	CTGGATTGATGTAAGAAGCGGGG	ITCH	ENSG00000078747	2.7787514067161068	[158]	[240,1016,NaN]	9	hSpCas9	negative selection	10071860
34457389	34457412	20	+	28162770	P31FUJ	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.6071977191958768	[34]	[26]	-5	hSpCas9	negative selection	10176065
34445290	34445313	20	+	28162770	P31FUJ	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.3064034725484456	[330]	[480]	3	hSpCas9	negative selection	10176066
34424479	34424502	20	+	28162770	P31FUJ	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.38949644757975044	[88]	[136]	4	hSpCas9	negative selection	10176067
34438607	34438630	20	-	28162770	P31FUJ	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.10519425910063751	[124]	[157]	1	hSpCas9	negative selection	10176068
34449468	34449491	20	-	28162770	P31FUJ	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.26783177745750564	[363]	[514]	3	hSpCas9	negative selection	10176069
34481142	34481165	20	+	28162770	P31FUJ	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	0.0834571403862916	[101]	[126]	0	hSpCas9	negative selection	10176070
34489262	34489285	20	+	28162770	P31FUJ	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.01662176990076214	[354]	[421]	0	hSpCas9	negative selection	10176071
34438517	34438540	20	+	28162770	P31FUJ	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	-0.3266691278786009	[126]	[118]	-3	hSpCas9	negative selection	10176072
34438595	34438618	20	-	28162770	P31FUJ	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-3.9817404402466607	[483]	[35]	-9	hSpCas9	negative selection	10176073
34440175	34440198	20	+	28162770	P31FUJ	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.33423838830951513	[323]	[479]	3	hSpCas9	negative selection	10176074
34457389	34457412	20	+	28162770	TF1	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10345431
34445290	34445313	20	+	28162770	TF1	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	NaN	[NaN]	[521]	1	hSpCas9	negative selection	10345432
34424479	34424502	20	+	28162770	TF1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	NaN	[NaN]	[161]	1	hSpCas9	negative selection	10345433
34438607	34438630	20	-	28162770	TF1	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	NaN	[NaN]	[195]	1	hSpCas9	negative selection	10345434
34449468	34449491	20	-	28162770	TF1	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	NaN	[NaN]	[181]	1	hSpCas9	negative selection	10345435
34481142	34481165	20	+	28162770	TF1	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	NaN	[NaN]	[221]	1	hSpCas9	negative selection	10345436
34489262	34489285	20	+	28162770	TF1	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	NaN	[NaN]	[441]	1	hSpCas9	negative selection	10345437
34438517	34438540	20	+	28162770	TF1	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	NaN	[NaN]	[85]	1	hSpCas9	negative selection	10345438
34438595	34438618	20	-	28162770	TF1	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10345439
34440175	34440198	20	+	28162770	TF1	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10345440
34457389	34457412	20	+	28162770	SKM1	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.014646775964401115	[11]	[20]	0	hSpCas9	negative selection	10514797
34445290	34445313	20	+	28162770	SKM1	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	-0.0005990014787686793	[72]	[128]	0	hSpCas9	negative selection	10514798
34424479	34424502	20	+	28162770	SKM1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.512982549690803	[43]	[110]	5	hSpCas9	negative selection	10514799
34438607	34438630	20	-	28162770	SKM1	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.4167851615651108	[49]	[117]	4	hSpCas9	negative selection	10514800
34449468	34449491	20	-	28162770	SKM1	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.7207913484552109	[80]	[235]	7	hSpCas9	negative selection	10514801
34481142	34481165	20	+	28162770	SKM1	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	0.8560702070906322	[29]	[95]	7	hSpCas9	negative selection	10514802
34489262	34489285	20	+	28162770	SKM1	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.13900417036213092	[74]	[145]	1	hSpCas9	negative selection	10514803
34438517	34438540	20	+	28162770	SKM1	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.5124173410485539	[22]	[57]	5	hSpCas9	negative selection	10514804
34438595	34438618	20	-	28162770	SKM1	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-1.2513944902779195	[100]	[74]	-7	hSpCas9	negative selection	10514805
34440175	34440198	20	+	28162770	SKM1	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.4224170296444413	[64]	[153]	4	hSpCas9	negative selection	10514806
34457389	34457412	20	+	28162770	SKM1	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.014646775964401115	[11]	[20]	0	hSpCas9	negative selection	10684163
34445290	34445313	20	+	28162770	SKM1	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	-0.0005990014787686793	[72]	[128]	0	hSpCas9	negative selection	10684164
34424479	34424502	20	+	28162770	SKM1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.512982549690803	[43]	[110]	5	hSpCas9	negative selection	10684165
34438607	34438630	20	-	28162770	SKM1	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.4167851615651108	[49]	[117]	4	hSpCas9	negative selection	10684166
34449468	34449491	20	-	28162770	SKM1	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.7207913484552109	[80]	[235]	7	hSpCas9	negative selection	10684167
34481142	34481165	20	+	28162770	SKM1	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	0.8560702070906322	[29]	[95]	7	hSpCas9	negative selection	10684168
34489262	34489285	20	+	28162770	SKM1	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.13900417036213092	[74]	[145]	1	hSpCas9	negative selection	10684169
34438517	34438540	20	+	28162770	SKM1	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.5124173410485539	[22]	[57]	5	hSpCas9	negative selection	10684170
34438595	34438618	20	-	28162770	SKM1	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-1.2513944902779195	[100]	[74]	-7	hSpCas9	negative selection	10684171
34440175	34440198	20	+	28162770	SKM1	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.4224170296444413	[64]	[153]	4	hSpCas9	negative selection	10684172
34457389	34457412	20	+	28162770	PL21	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	0.8897994938771696	[30]	[24]	7	hSpCas9	negative selection	10853529
34445290	34445313	20	+	28162770	PL21	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.8897994938771696	[216]	[174]	7	hSpCas9	negative selection	10853530
34424479	34424502	20	+	28162770	PL21	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-1.2723481569734236	[110]	[19]	-7	hSpCas9	negative selection	10853531
34438607	34438630	20	-	28162770	PL21	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	-0.10520559620243794	[172]	[69]	0	hSpCas9	negative selection	10853532
34449468	34449491	20	-	28162770	PL21	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	1.3354184731247414	[294]	[323]	9	hSpCas9	negative selection	10853533
34481142	34481165	20	+	28162770	PL21	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	0.44114771399311514	[131]	[77]	4	hSpCas9	negative selection	10853534
34489262	34489285	20	+	28162770	PL21	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	1.5518150527707346	[191]	[244]	9	hSpCas9	negative selection	10853535
34438517	34438540	20	+	28162770	PL21	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	1.2781421264905932	[71]	[75]	9	hSpCas9	negative selection	10853536
34438595	34438618	20	-	28162770	PL21	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-0.28131831047797606	[362]	[129]	-2	hSpCas9	negative selection	10853537
34440175	34440198	20	+	28162770	PL21	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	1.066873083625856	[169]	[154]	8	hSpCas9	negative selection	10853538
34457389	34457412	20	+	28162770	P31FUJ	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.6071977191958768	[34]	[26]	-5	hSpCas9	negative selection	11022895
34445290	34445313	20	+	28162770	P31FUJ	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.3064034725484456	[330]	[480]	3	hSpCas9	negative selection	11022896
34424479	34424502	20	+	28162770	P31FUJ	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.38949644757975044	[88]	[136]	4	hSpCas9	negative selection	11022897
34438607	34438630	20	-	28162770	P31FUJ	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.10519425910063751	[124]	[157]	1	hSpCas9	negative selection	11022898
34449468	34449491	20	-	28162770	P31FUJ	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.26783177745750564	[363]	[514]	3	hSpCas9	negative selection	11022899
34481142	34481165	20	+	28162770	P31FUJ	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	0.0834571403862916	[101]	[126]	0	hSpCas9	negative selection	11022900
34489262	34489285	20	+	28162770	P31FUJ	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.01662176990076214	[354]	[421]	0	hSpCas9	negative selection	11022901
34438517	34438540	20	+	28162770	P31FUJ	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	-0.3266691278786009	[126]	[118]	-3	hSpCas9	negative selection	11022902
34438595	34438618	20	-	28162770	P31FUJ	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-3.9817404402466607	[483]	[35]	-9	hSpCas9	negative selection	11022903
34440175	34440198	20	+	28162770	P31FUJ	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.33423838830951513	[323]	[479]	3	hSpCas9	negative selection	11022904
34457389	34457412	20	+	28162770	OCIAML5	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.5301384759766345	[19]	[24]	-4	hSpCas9	negative selection	11192261
34445290	34445313	20	+	28162770	OCIAML5	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	1.1078930689346522	[136]	[532]	8	hSpCas9	negative selection	11192262
34424479	34424502	20	+	28162770	OCIAML5	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	1.185801614726446	[46]	[192]	8	hSpCas9	negative selection	11192263
34438607	34438630	20	-	28162770	OCIAML5	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.8133457622771753	[92]	[294]	7	hSpCas9	negative selection	11192264
34449468	34449491	20	-	28162770	OCIAML5	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	1.222480382501057	[164]	[694]	9	hSpCas9	negative selection	11192265
34481142	34481165	20	+	28162770	OCIAML5	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	1.8865756011095929	[42]	[286]	9	hSpCas9	negative selection	11192266
34489262	34489285	20	+	28162770	OCIAML5	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	-0.07278241439306132	[214]	[368]	0	hSpCas9	negative selection	11192267
34438517	34438540	20	+	28162770	OCIAML5	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.3676114657754151	[75]	[176]	3	hSpCas9	negative selection	11192268
34438595	34438618	20	-	28162770	OCIAML5	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-2.5501431516366084	[304]	[93]	-8	hSpCas9	negative selection	11192269
34440175	34440198	20	+	28162770	OCIAML5	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.9955128288031053	[191]	[690]	8	hSpCas9	negative selection	11192270
34457389	34457412	20	+	28162770	EOL1	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-1.259876799566893	[99]	[21]	-7	hSpCas9	negative selection	11361627
34445290	34445313	20	+	28162770	EOL1	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.15636344679360822	[326]	[191]	1	hSpCas9	negative selection	11361628
34424479	34424502	20	+	28162770	EOL1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.12957657396876288	[202]	[116]	1	hSpCas9	negative selection	11361629
34438607	34438630	20	-	28162770	EOL1	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.04703177809552951	[315]	[171]	0	hSpCas9	negative selection	11361630
34449468	34449491	20	-	28162770	EOL1	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.01992581964779294	[555]	[296]	0	hSpCas9	negative selection	11361631
34481142	34481165	20	+	28162770	EOL1	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	0.46639005592187055	[282]	[205]	4	hSpCas9	negative selection	11361632
34489262	34489285	20	+	28162770	EOL1	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.5559031777761421	[305]	[236]	5	hSpCas9	negative selection	11361633
34438517	34438540	20	+	28162770	EOL1	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	-0.4539638516831952	[103]	[39]	-3	hSpCas9	negative selection	11361634
34438595	34438618	20	-	28162770	EOL1	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-2.4934922158698325	[480]	[44]	-8	hSpCas9	negative selection	11361635
34440175	34440198	20	+	28162770	EOL1	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	0.10300440663396379	[280]	[158]	0	hSpCas9	negative selection	11361636
34457389	34457412	20	+	28162770	MOLM13	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.5677345281861426	[81]	[39]	-3	hSpCas9	negative selection	11530993
34445290	34445313	20	+	28162770	MOLM13	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	-0.28653340969817376	[387]	[229]	-2	hSpCas9	negative selection	11530994
34424479	34424502	20	+	28162770	MOLM13	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.21836978218526654	[169]	[142]	1	hSpCas9	negative selection	11530995
34438607	34438630	20	-	28162770	MOLM13	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	1.5482085460563169	[261]	[553]	9	hSpCas9	negative selection	11530996
34449468	34449491	20	-	28162770	MOLM13	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	1.0159168719868115	[421]	[616]	7	hSpCas9	negative selection	11530997
34481142	34481165	20	+	28162770	MOLM13	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	1.1144215092671228	[236]	[370]	8	hSpCas9	negative selection	11530998
34489262	34489285	20	+	28162770	MOLM13	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.06476520380923578	[401]	[303]	0	hSpCas9	negative selection	11530999
34438517	34438540	20	+	28162770	MOLM13	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	-2.462847956018307	[121]	[15]	-8	hSpCas9	negative selection	11531000
34438595	34438618	20	-	28162770	MOLM13	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-1.8255322856537892	[450]	[91]	-7	hSpCas9	negative selection	11531001
34440175	34440198	20	+	28162770	MOLM13	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	-0.2799235948586197	[355]	[211]	-2	hSpCas9	negative selection	11531002
34457389	34457412	20	+	28162770	HEL	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.40032988989152907	[67]	[32]	-3	hSpCas9	negative selection	11700359
34445290	34445313	20	+	28162770	HEL	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	-0.22547129544410194	[344]	[188]	-2	hSpCas9	negative selection	11700360
34424479	34424502	20	+	28162770	HEL	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.4989223172232341	[138]	[62]	-3	hSpCas9	negative selection	11700361
34438607	34438630	20	-	28162770	HEL	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	1.1745899962619506	[165]	[239]	8	hSpCas9	negative selection	11700362
34449468	34449491	20	-	28162770	HEL	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	-0.40142875127521155	[397]	[192]	-3	hSpCas9	negative selection	11700363
34481142	34481165	20	+	28162770	HEL	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	-0.08595914618224881	[231]	[139]	0	hSpCas9	negative selection	11700364
34489262	34489285	20	+	28162770	HEL	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	-0.734862860576164	[316]	[121]	-5	hSpCas9	negative selection	11700365
34438517	34438540	20	+	28162770	HEL	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	-0.025639676908436826	[88]	[55]	0	hSpCas9	negative selection	11700366
34438595	34438618	20	-	28162770	HEL	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-3.9026118128219425	[466]	[19]	-9	hSpCas9	negative selection	11700367
34440175	34440198	20	+	28162770	HEL	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	-0.2583461419269557	[309]	[165]	-2	hSpCas9	negative selection	11700368
34457389	34457412	20	+	28162770	MV411	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	0.14310089096803935	[42]	[39]	1	hSpCas9	negative selection	11869725
34445290	34445313	20	+	28162770	MV411	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.7614168997552555	[242]	[346]	7	hSpCas9	negative selection	11869726
34424479	34424502	20	+	28162770	MV411	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.2979965857517437	[107]	[73]	-2	hSpCas9	negative selection	11869727
34438607	34438630	20	-	28162770	MV411	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.898103298554761	[185]	[291]	7	hSpCas9	negative selection	11869728
34449468	34449491	20	-	28162770	MV411	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.10810086917388595	[314]	[285]	0	hSpCas9	negative selection	11869729
34481142	34481165	20	+	28162770	MV411	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	-0.9749548705536726	[174]	[74]	-6	hSpCas9	negative selection	11869730
34489262	34489285	20	+	28162770	MV411	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.4437029444038681	[198]	[227]	4	hSpCas9	negative selection	11869731
34438517	34438540	20	+	28162770	MV411	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.42300911536622976	[84]	[95]	4	hSpCas9	negative selection	11869732
34438595	34438618	20	-	28162770	MV411	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-0.6599314713069603	[376]	[200]	-5	hSpCas9	negative selection	11869733
34440175	34440198	20	+	28162770	MV411	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	1.2568567031151692	[228]	[460]	9	hSpCas9	negative selection	11869734
34457389	34457412	20	+	28162770	MONOMAC1	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-2.518964941946916	[24]	[4]	-9	hSpCas9	negative selection	12039091
34445290	34445313	20	+	28162770	MONOMAC1	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	-0.40543599631650173	[170]	[147]	-4	hSpCas9	negative selection	12039092
34424479	34424502	20	+	28162770	MONOMAC1	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.587950261969596	[64]	[111]	6	hSpCas9	negative selection	12039093
34438607	34438630	20	-	28162770	MONOMAC1	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.45401484411937476	[127]	[200]	4	hSpCas9	negative selection	12039094
34449468	34449491	20	-	28162770	MONOMAC1	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.12333073384019166	[184]	[230]	1	hSpCas9	negative selection	12039095
34481142	34481165	20	+	28162770	MONOMAC1	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	-0.8930306601694538	[80]	[49]	-6	hSpCas9	negative selection	12039096
34489262	34489285	20	+	28162770	MONOMAC1	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.46221943600891663	[163]	[258]	4	hSpCas9	negative selection	12039097
34438517	34438540	20	+	28162770	MONOMAC1	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.10461885280154748	[42]	[52]	1	hSpCas9	negative selection	12039098
34438595	34438618	20	-	28162770	MONOMAC1	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-1.3438782353888246	[247]	[111]	-7	hSpCas9	negative selection	12039099
34440175	34440198	20	+	28162770	MONOMAC1	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	1.0883653718026949	[79]	[194]	8	hSpCas9	negative selection	12039100
34457389	34457412	20	+	28162770	OCIAML2	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-0.011198206604863703	[5]	[32]	0	hSpCas9	negative selection	12208457
34445290	34445313	20	+	28162770	OCIAML2	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.6481077213413615	[50]	[442]	6	hSpCas9	negative selection	12208458
34424479	34424502	20	+	28162770	OCIAML2	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	0.41689544549942625	[14]	[110]	4	hSpCas9	negative selection	12208459
34438607	34438630	20	-	28162770	OCIAML2	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.4541826783636197	[31]	[242]	4	hSpCas9	negative selection	12208460
34449468	34449491	20	-	28162770	OCIAML2	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	0.38481938501648805	[58]	[426]	3	hSpCas9	negative selection	12208461
34481142	34481165	20	+	28162770	OCIAML2	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	1.428545805238352	[24]	[372]	9	hSpCas9	negative selection	12208462
34489262	34489285	20	+	28162770	OCIAML2	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.5146736635511369	[36]	[292]	5	hSpCas9	negative selection	12208463
34438517	34438540	20	+	28162770	OCIAML2	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.3367250968154427	[12]	[90]	3	hSpCas9	negative selection	12208464
34438595	34438618	20	-	28162770	OCIAML2	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-2.011198206604864	[55]	[76]	-8	hSpCas9	negative selection	12208465
34440175	34440198	20	+	28162770	OCIAML2	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	1.5777331963192378	[21]	[363]	9	hSpCas9	negative selection	12208466
34457389	34457412	20	+	28162770	OCIAML3	viability	GAGAAGAGAACAGACAGCAATGG	ITCH	ENSG00000078747	-1.146548663352942	[10]	[14]	-7	hSpCas9	negative selection	12377823
34445290	34445313	20	+	28162770	OCIAML3	viability	GGAACGGCGGGTTGACAACATGG	ITCH	ENSG00000078747	0.6053011678992436	[80]	[371]	5	hSpCas9	negative selection	12377824
34424479	34424502	20	+	28162770	OCIAML3	viability	GGTGCTTCTCAGAATGATGATGG	ITCH	ENSG00000078747	-0.2720795454368008	[21]	[54]	-2	hSpCas9	negative selection	12377825
34438607	34438630	20	-	28162770	OCIAML3	viability	GGTCTACGTGGGGTGGGTGGTGG	ITCH	ENSG00000078747	0.5192029701238278	[48]	[211]	5	hSpCas9	negative selection	12377826
34449468	34449491	20	-	28162770	OCIAML3	viability	TGTGACTTACCCCATCCAGGTGG	ITCH	ENSG00000078747	1.7609922761688477	[68]	[705]	9	hSpCas9	negative selection	12377827
34481142	34481165	20	+	28162770	OCIAML3	viability	CATGATCTGAAACCTAATGGTGG	ITCH	ENSG00000078747	1.375618710632318	[35]	[281]	9	hSpCas9	negative selection	12377828
34489262	34489285	20	+	28162770	OCIAML3	viability	CCAGAATGGTAGCTGAGTGGAGG	ITCH	ENSG00000078747	0.20805298206392797	[77]	[271]	2	hSpCas9	negative selection	12377829
34438517	34438540	20	+	28162770	OCIAML3	viability	GGTGAAAATAGGAGAGTCAGTGG	ITCH	ENSG00000078747	0.011713420563790322	[22]	[69]	0	hSpCas9	negative selection	12377830
34438595	34438618	20	-	28162770	OCIAML3	viability	GTGGGTGGTGGTGGTCGTGAAGG	ITCH	ENSG00000078747	-1.4320401606607702	[100]	[112]	-7	hSpCas9	negative selection	12377831
34440175	34440198	20	+	28162770	OCIAML3	viability	TCTGCCACTTCTGAAAGTGATGG	ITCH	ENSG00000078747	-0.02265557112165989	[70]	[210]	0	hSpCas9	negative selection	12377832