| 105143493 | 105143516 | 14 | - | 26472758 | Jiyoye | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | -0.978715772113454 | [195] | [74] | -6 | hSpCas9 | negative selection | 80141 | 105151305 | 105151328 | 14 | - | 26472758 | Jiyoye | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.5739538276313219 | [203] | [228] | 4 | hSpCas9 | negative selection | 80142 | 105150634 | 105150657 | 14 | + | 26472758 | Jiyoye | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | 1.2816444994220146 | [23] | [43] | 7 | hSpCas9 | negative selection | 80143 | 105150609 | 105150632 | 14 | + | 26472758 | Jiyoye | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | 2.294700652247461 | [9] | [36] | 9 | hSpCas9 | negative selection | 80144 | 105150593 | 105150616 | 14 | + | 26472758 | Jiyoye | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 0.6333102045281382 | [164] | [192] | 4 | hSpCas9 | negative selection | 80145 | 105148773 | 105148796 | 14 | + | 26472758 | Jiyoye | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | 0.17271012786885054 | [39] | [33] | 1 | hSpCas9 | negative selection | 80146 | 105147488 | 105147511 | 14 | + | 26472758 | Jiyoye | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | -0.8784968280076523 | [333] | [136] | -6 | hSpCas9 | negative selection | 80147 | 105145035 | 105145058 | 14 | + | 26472758 | Jiyoye | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.9921378822270295 | [75] | [113] | 6 | hSpCas9 | negative selection | 80148 | 105143493 | 105143516 | 14 | - | 26472758 | KBM7 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | -0.5658205322916963 | [554,444] | [151,162] | -5 | hSpCas9 | negative selection | 271259 | 105151305 | 105151328 | 14 | - | 26472758 | KBM7 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.30315320227433085 | [628,573] | [461,247] | 3 | hSpCas9 | negative selection | 271260 | 105150634 | 105150657 | 14 | + | 26472758 | KBM7 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -0.353140906930585 | [538,333] | [117,192] | -3 | hSpCas9 | negative selection | 271261 | 105150609 | 105150632 | 14 | + | 26472758 | KBM7 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -1.161859709194204 | [206,86] | [24,33] | -7 | hSpCas9 | negative selection | 271262 | 105150593 | 105150616 | 14 | + | 26472758 | KBM7 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.2474148351489096 | [921,1041] | [387,397] | -2 | hSpCas9 | negative selection | 271263 | 105148773 | 105148796 | 14 | + | 26472758 | KBM7 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -2.1655198854872615 | [260,106] | [26,10] | -8 | hSpCas9 | negative selection | 271264 | 105147488 | 105147511 | 14 | + | 26472758 | KBM7 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.06984769915849898 | [672,756] | [352,359] | 0 | hSpCas9 | negative selection | 271265 | 105145035 | 105145058 | 14 | + | 26472758 | KBM7 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.5320319193654299 | [287,284] | [230,163] | 6 | hSpCas9 | negative selection | 271266 | 105143493 | 105143516 | 14 | - | 26472758 | Raji | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | -0.14787351986847524 | [295] | [61] | -1 | hSpCas9 | negative selection | 462377 | 105151305 | 105151328 | 14 | - | 26472758 | Raji | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | -0.11832924425445973 | [289] | [61] | -1 | hSpCas9 | negative selection | 462378 | 105150634 | 105150657 | 14 | + | 26472758 | Raji | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -2.7703607145754026 | [146] | [4] | -9 | hSpCas9 | negative selection | 462379 | 105150609 | 105150632 | 14 | + | 26472758 | Raji | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -1.2571888969222567 | [102] | [9] | -7 | hSpCas9 | negative selection | 462380 | 105150593 | 105150616 | 14 | + | 26472758 | Raji | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.029539543773498877 | [496] | [112] | 0 | hSpCas9 | negative selection | 462381 | 105148773 | 105148796 | 14 | + | 26472758 | Raji | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -2.395116805155584 | [135] | [5] | -9 | hSpCas9 | negative selection | 462382 | 105147488 | 105147511 | 14 | + | 26472758 | Raji | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | -0.4775789653475567 | [269] | [44] | -4 | hSpCas9 | negative selection | 462383 | 105145035 | 105145058 | 14 | + | 26472758 | Raji | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.14961177076289683 | [201] | [51] | 1 | hSpCas9 | negative selection | 462384 | 105143493 | 105143516 | 14 | - | 26472758 | K562 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.40649017111436736 | [613] | [686] | 3 | hSpCas9 | negative selection | 653495 | 105151305 | 105151328 | 14 | - | 26472758 | K562 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.7907310915639536 | [516] | [754] | 6 | hSpCas9 | negative selection | 653496 | 105150634 | 105150657 | 14 | + | 26472758 | K562 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -2.2087539004991683 | [229] | [41] | -7 | hSpCas9 | negative selection | 653497 | 105150609 | 105150632 | 14 | + | 26472758 | K562 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.9108594978114641 | [97] | [43] | -5 | hSpCas9 | negative selection | 653498 | 105150593 | 105150616 | 14 | + | 26472758 | K562 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.5745157132860403 | [687] | [389] | -4 | hSpCas9 | negative selection | 653499 | 105148773 | 105148796 | 14 | + | 26472758 | K562 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -0.05588655552112032 | [148] | [120] | 0 | hSpCas9 | negative selection | 653500 | 105147488 | 105147511 | 14 | + | 26472758 | K562 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | -0.5588434397572741 | [615] | [352] | -4 | hSpCas9 | negative selection | 653501 | 105145035 | 105145058 | 14 | + | 26472758 | K562 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.4819180413931031 | [284] | [335] | 4 | hSpCas9 | negative selection | 653502 | 105151322 | 105151345 | 14 | + | 26627737 | DLD1 | viability | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.2835146806392149 | [514] | [234,111,59] | -3 | hSpCas9 | negative selection | 787744 | 105151643 | 105151666 | 14 | - | 26627737 | DLD1 | viability | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 0.26161729218182567 | [273] | [87,171,57] | 2 | hSpCas9 | negative selection | 787745 | 105151937 | 105151960 | 14 | - | 26627737 | DLD1 | viability | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.3039893387281407 | [937] | [428,414,259] | 3 | hSpCas9 | negative selection | 787746 | 105151322 | 105151345 | 14 | + | 26627737 | GBM cells | viability after 5 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.21568026465726917 | [223] | [145,132] | 3 | hSpCas9 | negative selection | 870059 | 105151643 | 105151666 | 14 | - | 26627737 | GBM cells | viability after 5 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 0.6672436399612268 | [90] | [87,66] | 8 | hSpCas9 | negative selection | 870060 | 105151937 | 105151960 | 14 | - | 26627737 | GBM cells | viability after 5 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.3886731228519603 | [474] | [321,344] | 6 | hSpCas9 | negative selection | 870061 | 105151322 | 105151345 | 14 | + | 26627737 | GBM cells | viability after 13 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.06668680671804579 | [223] | [150,107] | 0 | hSpCas9 | negative selection | 952374 | 105151643 | 105151666 | 14 | - | 26627737 | GBM cells | viability after 13 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 0.5543638839308782 | [90] | [50,89] | 7 | hSpCas9 | negative selection | 952375 | 105151937 | 105151960 | 14 | - | 26627737 | GBM cells | viability after 13 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.33249215638298446 | [474] | [334,315] | 4 | hSpCas9 | negative selection | 952376 | 105151322 | 105151345 | 14 | + | 26627737 | GBM cells | viability after 21 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.17546652783760086 | [223] | [138,135] | 1 | hSpCas9 | negative selection | 1034689 | 105151643 | 105151666 | 14 | - | 26627737 | GBM cells | viability after 21 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 1.36200661601916 | [90] | [136,117] | 9 | hSpCas9 | negative selection | 1034690 | 105151937 | 105151960 | 14 | - | 26627737 | GBM cells | viability after 21 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.5782463677676791 | [474] | [448,326] | 6 | hSpCas9 | negative selection | 1034691 | 105151322 | 105151345 | 14 | + | 26627737 | RPE1 | viability after 9 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.18840039754548302 | [816] | [175,286] | -1 | hSpCas9 | negative selection | 1117004 | 105151643 | 105151666 | 14 | - | 26627737 | RPE1 | viability after 9 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 4.872877827259076 | [19] | [134,245] | 9 | hSpCas9 | negative selection | 1117005 | 105151937 | 105151960 | 14 | - | 26627737 | RPE1 | viability after 9 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.7169295234645078 | [1306] | [486,911] | 5 | hSpCas9 | negative selection | 1117006 | 105151322 | 105151345 | 14 | + | 26627737 | RPE1 | viability after 12 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.406770927523678 | [816] | [184,144] | -3 | hSpCas9 | negative selection | 1199319 | 105151643 | 105151666 | 14 | - | 26627737 | RPE1 | viability after 12 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 4.000927292565486 | [19] | [69,102] | 9 | hSpCas9 | negative selection | 1199320 | 105151937 | 105151960 | 14 | - | 26627737 | RPE1 | viability after 12 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.9918006625065329 | [1306] | [555,848] | 6 | hSpCas9 | negative selection | 1199321 | 105151322 | 105151345 | 14 | + | 26627737 | RPE1 | viability after 15 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.27085875631195555 | [816] | [343,215] | 1 | hSpCas9 | negative selection | 1281634 | 105151643 | 105151666 | 14 | - | 26627737 | RPE1 | viability after 15 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 4.737360619125475 | [19] | [155,145] | 9 | hSpCas9 | negative selection | 1281635 | 105151937 | 105151960 | 14 | - | 26627737 | RPE1 | viability after 15 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.8736765902389566 | [1306] | [623,728] | 5 | hSpCas9 | negative selection | 1281636 | 105151322 | 105151345 | 14 | + | 26627737 | RPE1 | viability after 18 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.4204179315198506 | [816] | [136,463] | 2 | hSpCas9 | negative selection | 1363949 | 105151643 | 105151666 | 14 | - | 26627737 | RPE1 | viability after 18 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 4.694628099126053 | [19] | [132,146] | 9 | hSpCas9 | negative selection | 1363950 | 105151937 | 105151960 | 14 | - | 26627737 | RPE1 | viability after 18 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.8427789033036682 | [1306] | [518,753] | 5 | hSpCas9 | negative selection | 1363951 | 105151322 | 105151345 | 14 | + | 26627737 | HeLa | viability after 8 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.06695578607754044 | [490] | [223,142,298] | 0 | hSpCas9 | negative selection | 1446264 | 105151643 | 105151666 | 14 | - | 26627737 | HeLa | viability after 8 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 2.8871699435299214 | [38] | [173,97,115] | 9 | hSpCas9 | negative selection | 1446265 | 105151937 | 105151960 | 14 | - | 26627737 | HeLa | viability after 8 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.7038459016077324 | [739] | [484,706,382] | 6 | hSpCas9 | negative selection | 1446266 | 105151322 | 105151345 | 14 | + | 26627737 | HeLa | viability after 12 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.7062646653225566 | [490] | [63,221,74] | -6 | hSpCas9 | negative selection | 1528579 | 105151643 | 105151666 | 14 | - | 26627737 | HeLa | viability after 12 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 2.7455035384408 | [38] | [142,138,39] | 9 | hSpCas9 | negative selection | 1528580 | 105151937 | 105151960 | 14 | - | 26627737 | HeLa | viability after 12 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.5194851057105304 | [739] | [490,434,390] | 4 | hSpCas9 | negative selection | 1528581 | 105151322 | 105151345 | 14 | + | 26627737 | HeLa | viability after 15 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.016860815459376066 | [490] | [140,259,191] | 0 | hSpCas9 | negative selection | 1610894 | 105151643 | 105151666 | 14 | - | 26627737 | HeLa | viability after 15 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 2.44386368838902 | [38] | [162,34,57] | 9 | hSpCas9 | negative selection | 1610895 | 105151937 | 105151960 | 14 | - | 26627737 | HeLa | viability after 15 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.8211672786727592 | [739] | [655,481,450] | 6 | hSpCas9 | negative selection | 1610896 | 105151322 | 105151345 | 14 | + | 26627737 | HeLa | viability after 18 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.04504925254444597 | [490] | [88,212,191] | 0 | hSpCas9 | negative selection | 1693209 | 105151643 | 105151666 | 14 | - | 26627737 | HeLa | viability after 18 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 2.3502937445594743 | [38] | [97,29,57] | 9 | hSpCas9 | negative selection | 1693210 | 105151937 | 105151960 | 14 | - | 26627737 | HeLa | viability after 18 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.8263950935753986 | [739] | [439,403,450] | 6 | hSpCas9 | negative selection | 1693211 | 105151322 | 105151345 | 14 | + | 26627737 | HCT116 | viability after 6 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -1.2670393941942515 | [1012] | [109,41] | -6 | hSpCas9 | negative selection | 1775524 | 105151643 | 105151666 | 14 | - | 26627737 | HCT116 | viability after 6 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -0.18407393435337316 | [450] | [151,12] | -1 | hSpCas9 | negative selection | 1775525 | 105151937 | 105151960 | 14 | - | 26627737 | HCT116 | viability after 6 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.44718684479727977 | [1292] | [416,199] | 2 | hSpCas9 | negative selection | 1775526 | 105151322 | 105151345 | 14 | + | 26627737 | HCT116 | viability after 8 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.2211803320836402 | [344] | [161,218,281] | 2 | hSpCas9 | negative selection | 1857839 | 105151643 | 105151666 | 14 | - | 26627737 | HCT116 | viability after 8 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -0.27197547042365067 | [181] | [108,87,52] | -3 | hSpCas9 | negative selection | 1857840 | 105151937 | 105151960 | 14 | - | 26627737 | HCT116 | viability after 8 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.11824809278994586 | [715] | [465,524,295] | 1 | hSpCas9 | negative selection | 1857841 | 105151322 | 105151345 | 14 | + | 26627737 | HCT116 | viability after 9 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.38738655240350217 | [1012] | [265,159] | -3 | hSpCas9 | negative selection | 1940154 | 105151643 | 105151666 | 14 | - | 26627737 | HCT116 | viability after 9 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -0.77216594871341 | [450] | [98,47] | -5 | hSpCas9 | negative selection | 1940155 | 105151937 | 105151960 | 14 | - | 26627737 | HCT116 | viability after 9 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | -0.06558844412219234 | [1292] | [387,283] | 0 | hSpCas9 | negative selection | 1940156 | 105151322 | 105151345 | 14 | + | 26627737 | HCT116 | viability after 12 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.29533034407667946 | [344] | [171,225,273] | 3 | hSpCas9 | negative selection | 2022469 | 105151643 | 105151666 | 14 | - | 26627737 | HCT116 | viability after 12 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -0.12611731685455108 | [181] | [34,188,45] | -1 | hSpCas9 | negative selection | 2022470 | 105151937 | 105151960 | 14 | - | 26627737 | HCT116 | viability after 12 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.28826296219239134 | [715] | [376,593,417] | 3 | hSpCas9 | negative selection | 2022471 | 105151322 | 105151345 | 14 | + | 26627737 | HCT116 | viability after 15 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.2341295606402218 | [344] | [181,284,225] | 2 | hSpCas9 | negative selection | 2104784 | 105151643 | 105151666 | 14 | - | 26627737 | HCT116 | viability after 15 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -0.012987526686263129 | [181] | [85,150,71] | 0 | hSpCas9 | negative selection | 2104785 | 105151937 | 105151960 | 14 | - | 26627737 | HCT116 | viability after 15 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.3336135792954691 | [715] | [480,633,435] | 3 | hSpCas9 | negative selection | 2104786 | 105151322 | 105151345 | 14 | + | 26627737 | HCT116 | viability after 18 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.9401807531319191 | [344] | [227,469,248] | 7 | hSpCas9 | negative selection | 2187099 | 105151643 | 105151666 | 14 | - | 26627737 | HCT116 | viability after 18 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -0.392259398264988 | [181] | [66,50,84] | -4 | hSpCas9 | negative selection | 2187100 | 105151937 | 105151960 | 14 | - | 26627737 | HCT116 | viability after 18 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.2992816965141225 | [715] | [300,612,347] | 2 | hSpCas9 | negative selection | 2187101 | 105149256 | 105149279 | 14 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCTCGCTGCTATAACCTGGAGGG | JAG2 | ENSG00000184916 | -0.23048840822332675 | [5,4] | [5,1] | -3 | hSpCas9 | positive selection | 2996340 | 105149256 | 105149279 | 14 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCTCGCTGCTATAACCTGGAGGG | JAG2 | ENSG00000184916 | -0.03210573973517139 | [5,5] | [4,2] | 0 | hSpCas9 | positive selection | 3064198 | 105149256 | 105149279 | 14 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCTCGCTGCTATAACCTGGAGGG | JAG2 | ENSG00000184916 | -0.0236901117664832 | [] | [] | 0 | hSpCas9 | negative selection | 3433738 | 105149256 | 105149279 | 14 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTCGCTGCTATAACCTGGAGGG | JAG2 | ENSG00000184916 | 0.388879653273339 | [] | [] | 0 | hSpCas9 | negative selection | 3520493 | 105150593 | 105150616 | 14 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 1.12684080175552 | [] | [] | 1 | hSpCas9 | negative selection | 3520494 | 105149256 | 105149279 | 14 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCTCGCTGCTATAACCTGGAGGG | JAG2 | ENSG00000184916 | 4.51405134678064 | [] | [] | 4 | hSpCas9 | negative selection | 3629152 | 105150593 | 105150616 | 14 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 1.66804908184241 | [] | [] | 2 | hSpCas9 | negative selection | 3629153 | 105149256 | 105149279 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTCGCTGCTATAACCTGGAGGG | JAG2 | ENSG00000184916 | -0.04316493729318388 | [5] | [5,5] | 0 | hSpCas9 | positive selection | 3737811 | 105150593 | 105150616 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 0.15877150855919595 | [3] | [3,4] | 4 | hSpCas9 | positive selection | 3737812 | 105149256 | 105149279 | 14 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTCGCTGCTATAACCTGGAGGG | JAG2 | ENSG00000184916 | 0.04413025145198057 | [6] | [5,6] | 0 | hSpCas9 | positive selection | 3846418 | 105150593 | 105150616 | 14 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.06089269113737181 | [4] | [3,4] | -1 | hSpCas9 | positive selection | 3846419 | 105149074 | 105149096 | 14 | + | 27760321 | OCIAML3 | viability | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.23932064146939946 | [523,379] | [430,389] | 3 | hSpCas9 | negative selection | 4410781 | 105149271 | 105149293 | 14 | + | 27760321 | OCIAML3 | viability | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.09827054266429062 | [437,321] | [276,364] | 1 | hSpCas9 | negative selection | 4410782 | 105151662 | 105151684 | 14 | + | 27760321 | OCIAML3 | viability | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.40001823701940514 | [584,553] | [494,709] | 5 | hSpCas9 | negative selection | 4410783 | 105149074 | 105149096 | 14 | + | 27760321 | OCIAML2 | viability | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | -0.3130944429787177 | [523,379] | [227,374] | -4 | hSpCas9 | negative selection | 4494244 | 105149271 | 105149293 | 14 | + | 27760321 | OCIAML2 | viability | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.4903202337429152 | [437,321] | [388,478] | 6 | hSpCas9 | negative selection | 4494245 | 105151662 | 105151684 | 14 | + | 27760321 | OCIAML2 | viability | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.4380796429805099 | [584,553] | [588,671] | 6 | hSpCas9 | negative selection | 4494246 | 105149074 | 105149096 | 14 | + | 27760321 | MV411 | viability | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 1.3452015782888902 | [523,379] | [984,397] | 8 | hSpCas9 | negative selection | 4577707 | 105149271 | 105149293 | 14 | + | 27760321 | MV411 | viability | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 1.3287515053397567 | [437,321] | [448,886] | 8 | hSpCas9 | negative selection | 4577708 | 105151662 | 105151684 | 14 | + | 27760321 | MV411 | viability | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.7132972495373995 | [584,553] | [629,596] | 5 | hSpCas9 | negative selection | 4577709 | 105149074 | 105149096 | 14 | + | 27760321 | HL60 | viability | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | -0.33025357574759107 | [523,379] | [300,279] | -4 | hSpCas9 | negative selection | 4661170 | 105149271 | 105149293 | 14 | + | 27760321 | HL60 | viability | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 1.570312826892937 | [437,321] | [1370,427] | 9 | hSpCas9 | negative selection | 4661171 | 105151662 | 105151684 | 14 | + | 27760321 | HL60 | viability | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | -0.21689835260501683 | [584,553] | [373,428] | -2 | hSpCas9 | negative selection | 4661172 | 105149074 | 105149096 | 14 | + | 27760321 | HT1080 | viability | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 1.3732147417720943 | [379,296] | [145,571] | 7 | hSpCas9 | negative selection | 4744633 | 105149271 | 105149293 | 14 | + | 27760321 | HT1080 | viability | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.7778583751768877 | [321,250] | [230,156] | 4 | hSpCas9 | negative selection | 4744634 | 105151662 | 105151684 | 14 | + | 27760321 | HT1080 | viability | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.2151706217393361 | [553,432] | [306,141] | 1 | hSpCas9 | negative selection | 4744635 | 105149074 | 105149096 | 14 | + | 27760321 | HT29 | viability after 7 days | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.4809552430169533 | [379,296] | [520,769,520] | 7 | hSpCas9 | negative selection | 4828096 | 105149271 | 105149293 | 14 | + | 27760321 | HT29 | viability after 7 days | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.27538473780376377 | [321,250] | [388,409,526] | 4 | hSpCas9 | negative selection | 4828097 | 105151662 | 105151684 | 14 | + | 27760321 | HT29 | viability after 7 days | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.01125163412501623 | [553,432] | [659,475,779] | 0 | hSpCas9 | negative selection | 4828098 | 105149074 | 105149096 | 14 | + | 27760321 | HT29 | viability after 25 days | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.6667909631550611 | [379,296] | [513,589,758] | 7 | hSpCas9 | negative selection | 4911559 | 105149271 | 105149293 | 14 | + | 27760321 | HT29 | viability after 25 days | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.6541193613306338 | [321,250] | [411,402,761] | 7 | hSpCas9 | negative selection | 4911560 | 105151662 | 105151684 | 14 | + | 27760321 | HT29 | viability after 25 days | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.18496001367900072 | [553,432] | [491,565,900] | 1 | hSpCas9 | negative selection | 4911561 | 105149074 | 105149096 | 14 | + | 27760321 | HT29 | viability after 22 days | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.7126893339535066 | [379,296] | [413,587,930] | 7 | hSpCas9 | negative selection | 4995022 | 105149271 | 105149293 | 14 | + | 27760321 | HT29 | viability after 22 days | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.7273964944159135 | [321,250] | [585,292,766] | 7 | hSpCas9 | negative selection | 4995023 | 105151662 | 105151684 | 14 | + | 27760321 | HT29 | viability after 22 days | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.28459712155612693 | [553,432] | [675,759,648] | 3 | hSpCas9 | negative selection | 4995024 | 105149074 | 105149096 | 14 | + | 27760321 | HT29 | viability after 19 days | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 1.1922195193666365 | [379,296] | [536,1192,886] | 9 | hSpCas9 | negative selection | 5078485 | 105149271 | 105149293 | 14 | + | 27760321 | HT29 | viability after 19 days | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.5744182721636899 | [321,250] | [582,582,313] | 6 | hSpCas9 | negative selection | 5078486 | 105151662 | 105151684 | 14 | + | 27760321 | HT29 | viability after 19 days | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.03985604781884333 | [553,432] | [562,632,543] | 0 | hSpCas9 | negative selection | 5078487 | 105149074 | 105149096 | 14 | + | 27760321 | HT29 | viability after 16 days | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.8904784730949165 | [379,296] | [866,503,755] | 9 | hSpCas9 | negative selection | 5161948 | 105149271 | 105149293 | 14 | + | 27760321 | HT29 | viability after 16 days | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.35960983999375085 | [321,250] | [381,215,637] | 4 | hSpCas9 | negative selection | 5161949 | 105151662 | 105151684 | 14 | + | 27760321 | HT29 | viability after 16 days | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.3711841686205709 | [553,432] | [780,705,661] | 4 | hSpCas9 | negative selection | 5161950 | 105149074 | 105149096 | 14 | + | 27760321 | HT29 | viability after 13 days | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.5205717439041899 | [379,296] | [394,434,842] | 6 | hSpCas9 | negative selection | 5245411 | 105149271 | 105149293 | 14 | + | 27760321 | HT29 | viability after 13 days | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.16556401470106602 | [321,250] | [299,370,442] | 2 | hSpCas9 | negative selection | 5245412 | 105151662 | 105151684 | 14 | + | 27760321 | HT29 | viability after 13 days | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.4635368824066992 | [553,432] | [838,785,745] | 6 | hSpCas9 | negative selection | 5245413 | 105149074 | 105149096 | 14 | + | 27760321 | HT29 | viability after 10 days | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.6341565247721254 | [379,296] | [513,901,560] | 8 | hSpCas9 | negative selection | 5328874 | 105149271 | 105149293 | 14 | + | 27760321 | HT29 | viability after 10 days | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.05674881218723882 | [321,250] | [646,147,315] | 0 | hSpCas9 | negative selection | 5328875 | 105151662 | 105151684 | 14 | + | 27760321 | HT29 | viability after 10 days | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | -0.015142159638874497 | [553,432] | [610,483,727] | 0 | hSpCas9 | negative selection | 5328876 | 105149074 | 105149096 | 14 | + | 27760321 | MOLM13 | viability | CCGCAGCCATCGATCACTATGG | JAG2 | ENSG00000184916 | 0.16658958401877308 | [523,379] | [391,190] | 1 | hSpCas9 | negative selection | 5412337 | 105149271 | 105149293 | 14 | + | 27760321 | MOLM13 | viability | CAGCGAGCGCCGTTCCGGCAGG | JAG2 | ENSG00000184916 | 0.9485900872110797 | [437,321] | [302,500] | 6 | hSpCas9 | negative selection | 5412338 | 105151662 | 105151684 | 14 | + | 27760321 | MOLM13 | viability | AGTGGCATTCGAAGCCGGACGG | JAG2 | ENSG00000184916 | 0.7337125756304694 | [584,553] | [502,561] | 5 | hSpCas9 | negative selection | 5412339 | 105151322 | 105151345 | 14 | + | 27869803 | HPAFII | viability after 27 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 1.1533505920975202 | [204] | [302,186,NaN] | 8 | hSpCas9 | negative selection | 9550750 | 105151643 | 105151666 | 14 | - | 27869803 | HPAFII | viability after 27 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 2.170294875829901 | [64] | [203,111,NaN] | 9 | hSpCas9 | negative selection | 9550751 | 105151937 | 105151960 | 14 | - | 27869803 | HPAFII | viability after 27 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.2327249453229312 | [796] | [511,475,NaN] | 1 | hSpCas9 | negative selection | 9550752 | 105151322 | 105151345 | 14 | + | 27869803 | HPAFII | viability after 15 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.7106555831187635 | [204] | [502,271,NaN] | 7 | hSpCas9 | negative selection | 9633199 | 105151643 | 105151666 | 14 | - | 27869803 | HPAFII | viability after 15 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 1.0670744239527057 | [64] | [117,163,NaN] | 9 | hSpCas9 | negative selection | 9633200 | 105151937 | 105151960 | 14 | - | 27869803 | HPAFII | viability after 15 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.08735455207854526 | [796] | [1361,628,NaN] | 1 | hSpCas9 | negative selection | 9633201 | 105151322 | 105151345 | 14 | + | 27869803 | ASPC1 | viability after 36 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | -0.11380071608196018 | [500] | [13,359,105] | -1 | hSpCas9 | negative selection | 9715648 | 105151643 | 105151666 | 14 | - | 27869803 | ASPC1 | viability after 36 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 2.1996439871965587 | [105] | [5,71,360] | 9 | hSpCas9 | negative selection | 9715649 | 105151937 | 105151960 | 14 | - | 27869803 | ASPC1 | viability after 36 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.16039830943174738 | [1530] | [749,518,545] | 1 | hSpCas9 | negative selection | 9715650 | 105151322 | 105151345 | 14 | + | 27869803 | PATU8988S | viability after 35 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.023696629636936584 | [668] | [230,316,NaN] | 0 | hSpCas9 | negative selection | 9798097 | 105151643 | 105151666 | 14 | - | 27869803 | PATU8988S | viability after 35 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -1.6742626267044378 | [245] | [49,11,NaN] | -8 | hSpCas9 | negative selection | 9798098 | 105151937 | 105151960 | 14 | - | 27869803 | PATU8988S | viability after 35 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.7193773454501191 | [1376] | [961,863,NaN] | 7 | hSpCas9 | negative selection | 9798099 | 105151322 | 105151345 | 14 | + | 27869803 | PATU8988S | viability after 31 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 0.24740533157462963 | [668] | [229,426,NaN] | 3 | hSpCas9 | negative selection | 9880546 | 105151643 | 105151666 | 14 | - | 27869803 | PATU8988S | viability after 31 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | -1.425371541390025 | [245] | [43,26,NaN] | -8 | hSpCas9 | negative selection | 9880547 | 105151937 | 105151960 | 14 | - | 27869803 | PATU8988S | viability after 31 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.44879715230016903 | [1376] | [682,833,NaN] | 5 | hSpCas9 | negative selection | 9880548 | 105151322 | 105151345 | 14 | + | 27869803 | HPAFII | viability after 35 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 1.4192914336565619 | [204] | [230,329,NaN] | 8 | hSpCas9 | negative selection | 9962995 | 105151643 | 105151666 | 14 | - | 27869803 | HPAFII | viability after 35 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 2.0263630376339576 | [64] | [118,150,NaN] | 9 | hSpCas9 | negative selection | 9962996 | 105151937 | 105151960 | 14 | - | 27869803 | HPAFII | viability after 35 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | -0.05361549238712171 | [796] | [376,401,NaN] | 0 | hSpCas9 | negative selection | 9962997 | 105151322 | 105151345 | 14 | + | 27869803 | HPAFII | viability after 31 days | TGCACTCAAAGCCGTCCACCTGG | JAG2 | ENSG00000184916 | 1.344209648111628 | [204] | [271,313,NaN] | 8 | hSpCas9 | negative selection | 10045444 | 105151643 | 105151666 | 14 | - | 27869803 | HPAFII | viability after 31 days | CACTGCCCATCGGGCTGGAGCGG | JAG2 | ENSG00000184916 | 1.8097952679097236 | [64] | [158,93,NaN] | 9 | hSpCas9 | negative selection | 10045445 | 105151937 | 105151960 | 14 | - | 27869803 | HPAFII | viability after 31 days | TCGGGCAGGAACTGTGAGAAGGG | JAG2 | ENSG00000184916 | 0.08493892889074206 | [796] | [438,512,NaN] | 0 | hSpCas9 | negative selection | 10045446 | 105143493 | 105143516 | 14 | - | 28162770 | P31FUJ | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.47231905934117563 | [283] | [462] | 5 | hSpCas9 | negative selection | 10176680 | 105151305 | 105151328 | 14 | - | 28162770 | P31FUJ | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.06711726953922387 | [250] | [308] | 0 | hSpCas9 | negative selection | 10176681 | 105150634 | 105150657 | 14 | + | 28162770 | P31FUJ | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -1.0190955109441528 | [118] | [68] | -6 | hSpCas9 | negative selection | 10176682 | 105150609 | 105150632 | 14 | + | 28162770 | P31FUJ | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -1.0292688103292469 | [65] | [37] | -6 | hSpCas9 | negative selection | 10176683 | 105150593 | 105150616 | 14 | + | 28162770 | P31FUJ | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.5418338569079139 | [528] | [426] | -4 | hSpCas9 | negative selection | 10176684 | 105148773 | 105148796 | 14 | + | 28162770 | P31FUJ | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -0.13882605620536492 | [103] | [110] | -1 | hSpCas9 | negative selection | 10176685 | 105147488 | 105147511 | 14 | + | 28162770 | P31FUJ | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.2221440163011016 | [409] | [561] | 2 | hSpCas9 | negative selection | 10176686 | 105145035 | 105145058 | 14 | + | 28162770 | P31FUJ | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.3833212277932382 | [228] | [350] | 4 | hSpCas9 | negative selection | 10176687 | 105143493 | 105143516 | 14 | - | 28162770 | TF1 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [310] | 1 | hSpCas9 | negative selection | 10346046 | 105151305 | 105151328 | 14 | - | 28162770 | TF1 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [302] | 1 | hSpCas9 | negative selection | 10346047 | 105150634 | 105150657 | 14 | + | 28162770 | TF1 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [11] | 1 | hSpCas9 | negative selection | 10346048 | 105150609 | 105150632 | 14 | + | 28162770 | TF1 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [68] | 1 | hSpCas9 | negative selection | 10346049 | 105150593 | 105150616 | 14 | + | 28162770 | TF1 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [280] | 1 | hSpCas9 | negative selection | 10346050 | 105148773 | 105148796 | 14 | + | 28162770 | TF1 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [25] | 1 | hSpCas9 | negative selection | 10346051 | 105147488 | 105147511 | 14 | + | 28162770 | TF1 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [153] | 1 | hSpCas9 | negative selection | 10346052 | 105145035 | 105145058 | 14 | + | 28162770 | TF1 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | NaN | [NaN] | [204] | 1 | hSpCas9 | negative selection | 10346053 | 105143493 | 105143516 | 14 | - | 28162770 | SKM1 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.7874138464236896 | [77] | [237] | 7 | hSpCas9 | negative selection | 10515412 | 105151305 | 105151328 | 14 | - | 28162770 | SKM1 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.34572574771606096 | [72] | [163] | 3 | hSpCas9 | negative selection | 10515413 | 105150634 | 105150657 | 14 | + | 28162770 | SKM1 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | 0.722318818201805 | [23] | [69] | 7 | hSpCas9 | negative selection | 10515414 | 105150609 | 105150632 | 14 | + | 28162770 | SKM1 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -1.143929792909368 | [24] | [19] | -7 | hSpCas9 | negative selection | 10515415 | 105150593 | 105150616 | 14 | + | 28162770 | SKM1 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.5962889183939463 | [123] | [144] | -5 | hSpCas9 | negative selection | 10515416 | 105148773 | 105148796 | 14 | + | 28162770 | SKM1 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -1.3580545982622154 | [28] | [19] | -7 | hSpCas9 | negative selection | 10515417 | 105147488 | 105147511 | 14 | + | 28162770 | SKM1 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.07346771850668754 | [92] | [172] | 0 | hSpCas9 | negative selection | 10515418 | 105145035 | 105145058 | 14 | + | 28162770 | SKM1 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | -0.07306346218972337 | [71] | [120] | 0 | hSpCas9 | negative selection | 10515419 | 105143493 | 105143516 | 14 | - | 28162770 | SKM1 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.7874138464236896 | [77] | [237] | 7 | hSpCas9 | negative selection | 10684778 | 105151305 | 105151328 | 14 | - | 28162770 | SKM1 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.34572574771606096 | [72] | [163] | 3 | hSpCas9 | negative selection | 10684779 | 105150634 | 105150657 | 14 | + | 28162770 | SKM1 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | 0.722318818201805 | [23] | [69] | 7 | hSpCas9 | negative selection | 10684780 | 105150609 | 105150632 | 14 | + | 28162770 | SKM1 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -1.143929792909368 | [24] | [19] | -7 | hSpCas9 | negative selection | 10684781 | 105150593 | 105150616 | 14 | + | 28162770 | SKM1 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.5962889183939463 | [123] | [144] | -5 | hSpCas9 | negative selection | 10684782 | 105148773 | 105148796 | 14 | + | 28162770 | SKM1 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -1.3580545982622154 | [28] | [19] | -7 | hSpCas9 | negative selection | 10684783 | 105147488 | 105147511 | 14 | + | 28162770 | SKM1 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.07346771850668754 | [92] | [172] | 0 | hSpCas9 | negative selection | 10684784 | 105145035 | 105145058 | 14 | + | 28162770 | SKM1 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | -0.07306346218972337 | [71] | [120] | 0 | hSpCas9 | negative selection | 10684785 | 105143493 | 105143516 | 14 | - | 28162770 | PL21 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | -0.5792612459972826 | [229] | [66] | -4 | hSpCas9 | negative selection | 10854144 | 105151305 | 105151328 | 14 | - | 28162770 | PL21 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 1.117282682085036 | [214] | [202] | 8 | hSpCas9 | negative selection | 10854145 | 105150634 | 105150657 | 14 | + | 28162770 | PL21 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | 0.6931796257694371 | [80] | [56] | 6 | hSpCas9 | negative selection | 10854146 | 105150609 | 105150632 | 14 | + | 28162770 | PL21 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | 0.7113924290274672 | [86] | [61] | 6 | hSpCas9 | negative selection | 10854147 | 105150593 | 105150616 | 14 | + | 28162770 | PL21 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 0.030214613047007788 | [350] | [155] | 0 | hSpCas9 | negative selection | 10854148 | 105148773 | 105148796 | 14 | + | 28162770 | PL21 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -1.969785386952992 | [62] | [6] | -8 | hSpCas9 | negative selection | 10854149 | 105147488 | 105147511 | 14 | + | 28162770 | PL21 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.3078957948452029 | [244] | [131] | 2 | hSpCas9 | negative selection | 10854150 | 105145035 | 105145058 | 14 | + | 28162770 | PL21 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.9354363882949078 | [172] | [143] | 7 | hSpCas9 | negative selection | 10854151 | 105143493 | 105143516 | 14 | - | 28162770 | P31FUJ | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.47231905934117563 | [283] | [462] | 5 | hSpCas9 | negative selection | 11023510 | 105151305 | 105151328 | 14 | - | 28162770 | P31FUJ | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.06711726953922387 | [250] | [308] | 0 | hSpCas9 | negative selection | 11023511 | 105150634 | 105150657 | 14 | + | 28162770 | P31FUJ | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -1.0190955109441528 | [118] | [68] | -6 | hSpCas9 | negative selection | 11023512 | 105150609 | 105150632 | 14 | + | 28162770 | P31FUJ | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -1.0292688103292469 | [65] | [37] | -6 | hSpCas9 | negative selection | 11023513 | 105150593 | 105150616 | 14 | + | 28162770 | P31FUJ | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.5418338569079139 | [528] | [426] | -4 | hSpCas9 | negative selection | 11023514 | 105148773 | 105148796 | 14 | + | 28162770 | P31FUJ | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -0.13882605620536492 | [103] | [110] | -1 | hSpCas9 | negative selection | 11023515 | 105147488 | 105147511 | 14 | + | 28162770 | P31FUJ | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.2221440163011016 | [409] | [561] | 2 | hSpCas9 | negative selection | 11023516 | 105145035 | 105145058 | 14 | + | 28162770 | P31FUJ | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.3833212277932382 | [228] | [350] | 4 | hSpCas9 | negative selection | 11023517 | 105143493 | 105143516 | 14 | - | 28162770 | OCIAML5 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | -0.09611787333021787 | [150] | [254] | 0 | hSpCas9 | negative selection | 11192876 | 105151305 | 105151328 | 14 | - | 28162770 | OCIAML5 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.7694218058822732 | [103] | [319] | 6 | hSpCas9 | negative selection | 11192877 | 105150634 | 105150657 | 14 | + | 28162770 | OCIAML5 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -1.4022636534244766 | [40] | [27] | -7 | hSpCas9 | negative selection | 11192878 | 105150609 | 105150632 | 14 | + | 28162770 | OCIAML5 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.30272797987356204 | [40] | [59] | -2 | hSpCas9 | negative selection | 11192879 | 105150593 | 105150616 | 14 | + | 28162770 | OCIAML5 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 0.021241424220140526 | [225] | [413] | 0 | hSpCas9 | negative selection | 11192880 | 105148773 | 105148796 | 14 | + | 28162770 | OCIAML5 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -2.6020883178556495 | [73] | [21] | -8 | hSpCas9 | negative selection | 11192881 | 105147488 | 105147511 | 14 | + | 28162770 | OCIAML5 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | -0.38258128756277665 | [194] | [269] | -3 | hSpCas9 | negative selection | 11192882 | 105145035 | 105145058 | 14 | + | 28162770 | OCIAML5 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.6759688617723236 | [111] | [322] | 6 | hSpCas9 | negative selection | 11192883 | 105143493 | 105143516 | 14 | - | 28162770 | EOL1 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 1.1642748039122595 | [259] | [306] | 8 | hSpCas9 | negative selection | 11362242 | 105151305 | 105151328 | 14 | - | 28162770 | EOL1 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.4858866677657916 | [430] | [317] | 4 | hSpCas9 | negative selection | 11362243 | 105150634 | 105150657 | 14 | + | 28162770 | EOL1 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -1.601175525775946 | [166] | [28] | -7 | hSpCas9 | negative selection | 11362244 | 105150609 | 105150632 | 14 | + | 28162770 | EOL1 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | 0.10897234270796186 | [175] | [99] | 1 | hSpCas9 | negative selection | 11362245 | 105150593 | 105150616 | 14 | + | 28162770 | EOL1 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.9566561803743345 | [500] | [135] | -6 | hSpCas9 | negative selection | 11362246 | 105148773 | 105148796 | 14 | + | 28162770 | EOL1 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | 1.216998665381063 | [88] | [108] | 8 | hSpCas9 | negative selection | 11362247 | 105147488 | 105147511 | 14 | + | 28162770 | EOL1 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.023862325488723912 | [434] | [232] | 0 | hSpCas9 | negative selection | 11362248 | 105145035 | 105145058 | 14 | + | 28162770 | EOL1 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.7491057651606564 | [261] | [231] | 6 | hSpCas9 | negative selection | 11362249 | 105143493 | 105143516 | 14 | - | 28162770 | MOLM13 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.08601874620093425 | [257] | [197] | 0 | hSpCas9 | negative selection | 11531608 | 105151305 | 105151328 | 14 | - | 28162770 | MOLM13 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 1.0591491207269446 | [380] | [573] | 7 | hSpCas9 | negative selection | 11531609 | 105150634 | 105150657 | 14 | + | 28162770 | MOLM13 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | 0.6416564492812854 | [124] | [140] | 5 | hSpCas9 | negative selection | 11531610 | 105150609 | 105150632 | 14 | + | 28162770 | MOLM13 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.7830721919886399 | [118] | [49] | -4 | hSpCas9 | negative selection | 11531611 | 105150593 | 105150616 | 14 | + | 28162770 | MOLM13 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.2042250682716592 | [579] | [363] | -1 | hSpCas9 | negative selection | 11531612 | 105148773 | 105148796 | 14 | + | 28162770 | MOLM13 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -1.1681473037708467 | [114] | [36] | -6 | hSpCas9 | negative selection | 11531613 | 105147488 | 105147511 | 14 | + | 28162770 | MOLM13 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.22552854397553473 | [387] | [327] | 1 | hSpCas9 | negative selection | 11531614 | 105145035 | 105145058 | 14 | + | 28162770 | MOLM13 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.5038462593209885 | [316] | [324] | 4 | hSpCas9 | negative selection | 11531615 | 105143493 | 105143516 | 14 | - | 28162770 | HEL | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | -0.14044977892649493 | [221] | [128] | -1 | hSpCas9 | negative selection | 11700974 | 105151305 | 105151328 | 14 | - | 28162770 | HEL | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 1.2822702752609367 | [293] | [457] | 9 | hSpCas9 | negative selection | 11700975 | 105150634 | 105150657 | 14 | + | 28162770 | HEL | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | 0.24364287659053452 | [119] | [90] | 2 | hSpCas9 | negative selection | 11700976 | 105150609 | 105150632 | 14 | + | 28162770 | HEL | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.21524216312721522 | [86] | [47] | -1 | hSpCas9 | negative selection | 11700977 | 105150593 | 105150616 | 14 | + | 28162770 | HEL | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 0.5494062556630536 | [430] | [403] | 4 | hSpCas9 | negative selection | 11700978 | 105148773 | 105148796 | 14 | + | 28162770 | HEL | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -0.6166477968182926 | [78] | [32] | -4 | hSpCas9 | negative selection | 11700979 | 105147488 | 105147511 | 14 | + | 28162770 | HEL | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.3806086537366772 | [318] | [265] | 3 | hSpCas9 | negative selection | 11700980 | 105145035 | 105145058 | 14 | + | 28162770 | HEL | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.4040813563011247 | [222] | [188] | 3 | hSpCas9 | negative selection | 11700981 | 105143493 | 105143516 | 14 | - | 28162770 | MV411 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.48963845319940347 | [185] | [219] | 4 | hSpCas9 | negative selection | 11870340 | 105151305 | 105151328 | 14 | - | 28162770 | MV411 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.00045555023434762365 | [285] | [240] | 0 | hSpCas9 | negative selection | 11870341 | 105150634 | 105150657 | 14 | + | 28162770 | MV411 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -1.0226516125849687 | [122] | [50] | -6 | hSpCas9 | negative selection | 11870342 | 105150609 | 105150632 | 14 | + | 28162770 | MV411 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.09263789081484652 | [99] | [78] | 0 | hSpCas9 | negative selection | 11870343 | 105150593 | 105150616 | 14 | + | 28162770 | MV411 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.3395356750595273 | [358] | [238] | -3 | hSpCas9 | negative selection | 11870344 | 105148773 | 105148796 | 14 | + | 28162770 | MV411 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -4.291721260325256 | [92] | [3] | -9 | hSpCas9 | negative selection | 11870345 | 105147488 | 105147511 | 14 | + | 28162770 | MV411 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | -0.492695322462114 | [303] | [181] | -4 | hSpCas9 | negative selection | 11870346 | 105145035 | 105145058 | 14 | + | 28162770 | MV411 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.009090023800451263 | [196] | [166] | 0 | hSpCas9 | negative selection | 11870347 | 105143493 | 105143516 | 14 | - | 28162770 | MONOMAC1 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.5105705675078538 | [138] | [226] | 5 | hSpCas9 | negative selection | 12039706 | 105151305 | 105151328 | 14 | - | 28162770 | MONOMAC1 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.20350108252417515 | [149] | [197] | 2 | hSpCas9 | negative selection | 12039707 | 105150634 | 105150657 | 14 | + | 28162770 | MONOMAC1 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -0.4302360233525844 | [66] | [56] | -4 | hSpCas9 | negative selection | 12039708 | 105150609 | 105150632 | 14 | + | 28162770 | MONOMAC1 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.28192574464606657 | [69] | [65] | -2 | hSpCas9 | negative selection | 12039709 | 105150593 | 105150616 | 14 | + | 28162770 | MONOMAC1 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | 0.9492368863181133 | [163] | [362] | 8 | hSpCas9 | negative selection | 12039710 | 105148773 | 105148796 | 14 | + | 28162770 | MONOMAC1 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | 1.2138962538865534 | [43] | [116] | 9 | hSpCas9 | negative selection | 12039711 | 105147488 | 105147511 | 14 | + | 28162770 | MONOMAC1 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.7329534316927038 | [189] | [361] | 7 | hSpCas9 | negative selection | 12039712 | 105145035 | 105145058 | 14 | + | 28162770 | MONOMAC1 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | -0.6454973478758477 | [130] | [95] | -5 | hSpCas9 | negative selection | 12039713 | 105143493 | 105143516 | 14 | - | 28162770 | OCIAML2 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | -0.025844982569265283 | [35] | [195] | 0 | hSpCas9 | negative selection | 12209072 | 105151305 | 105151328 | 14 | - | 28162770 | OCIAML2 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.6659090077056045 | [33] | [298] | 6 | hSpCas9 | negative selection | 12209073 | 105150634 | 105150657 | 14 | + | 28162770 | OCIAML2 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -1.129592907407094 | [14] | [37] | -6 | hSpCas9 | negative selection | 12209074 | 105150609 | 105150632 | 14 | + | 28162770 | OCIAML2 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.3881676650501882 | [16] | [71] | -3 | hSpCas9 | negative selection | 12209075 | 105150593 | 105150616 | 14 | + | 28162770 | OCIAML2 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.6088271191621808 | [51] | [188] | -4 | hSpCas9 | negative selection | 12209076 | 105148773 | 105148796 | 14 | + | 28162770 | OCIAML2 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -0.6632749031845573 | [9] | [34] | -5 | hSpCas9 | negative selection | 12209077 | 105147488 | 105147511 | 14 | + | 28162770 | OCIAML2 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | -0.41064772041392883 | [52] | [220] | -3 | hSpCas9 | negative selection | 12209078 | 105145035 | 105145058 | 14 | + | 28162770 | OCIAML2 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 0.19864896141247051 | [35] | [228] | 2 | hSpCas9 | negative selection | 12209079 | 105143493 | 105143516 | 14 | - | 28162770 | OCIAML3 | viability | GTGGAGACGGTTGTTACGGGCGG | JAG2 | ENSG00000184916 | 0.9644130729445013 | [63] | [376] | 8 | hSpCas9 | negative selection | 12378438 | 105151305 | 105151328 | 14 | - | 28162770 | OCIAML3 | viability | AGTGCATCTGCCCCGAGCAGTGG | JAG2 | ENSG00000184916 | 0.2403143293337102 | [52] | [188] | 2 | hSpCas9 | negative selection | 12378439 | 105150634 | 105150657 | 14 | + | 28162770 | OCIAML3 | viability | GCAGTGGCAGTGGAAGCCGTCGG | JAG2 | ENSG00000184916 | -0.41343539468234236 | [14] | [33] | -3 | hSpCas9 | negative selection | 12378440 | 105150609 | 105150632 | 14 | + | 28162770 | OCIAML3 | viability | AGAGAGGCCCGGAGAAGCCCTGG | JAG2 | ENSG00000184916 | -0.08704765160427996 | [18] | [53] | 0 | hSpCas9 | negative selection | 12378441 | 105150593 | 105150616 | 14 | + | 28162770 | OCIAML3 | viability | GCAGACCTCACCTCACAGAGAGG | JAG2 | ENSG00000184916 | -0.7308894467445499 | [115] | [210] | -5 | hSpCas9 | negative selection | 12378442 | 105148773 | 105148796 | 14 | + | 28162770 | OCIAML3 | viability | GCTGGGGCAGAAGCAGCGGAAGG | JAG2 | ENSG00000184916 | -1.3845542746952133 | [31] | [36] | -7 | hSpCas9 | negative selection | 12378443 | 105147488 | 105147511 | 14 | + | 28162770 | OCIAML3 | viability | GGTGCCACTCACCAAGGCAGAGG | JAG2 | ENSG00000184916 | 0.10643207781692887 | [79] | [259] | 1 | hSpCas9 | negative selection | 12378444 | 105145035 | 105145058 | 14 | + | 28162770 | OCIAML3 | viability | GGAGCAAATGGCGCCCACCGTGG | JAG2 | ENSG00000184916 | 1.0292248773247106 | [30] | [190] | 8 | hSpCas9 | negative selection | 12378445 |