Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:10300
• Symbol:KATNB1
• Description:katanin regulatory subunit B1

DataSource: http://genomecrispr.dkfz.de/#!/results/KATNB1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
57753457	57753480	16	-	26472758	Jiyoye	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.779237742725008	[131]	[57]	-5	hSpCas9	negative selection	80698
57756446	57756469	16	+	26472758	Jiyoye	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	0.8926022086761152	[14]	[20]	6	hSpCas9	negative selection	80699
57744399	57744422	16	+	26472758	Jiyoye	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	0.515090720672761	[205]	[221]	4	hSpCas9	negative selection	80700
57744461	57744484	16	-	26472758	Jiyoye	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	0.05925207808556654	[55]	[43]	0	hSpCas9	negative selection	80701
57752545	57752568	16	+	26472758	Jiyoye	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.7602029378260924	[282]	[62]	-8	hSpCas9	negative selection	80702
57753178	57753201	16	-	26472758	Jiyoye	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	0.08067455682868696	[236]	[188]	0	hSpCas9	negative selection	80703
57753217	57753240	16	-	26472758	Jiyoye	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-0.4997152141026451	[14]	[7]	-4	hSpCas9	negative selection	80704
57754964	57754987	16	-	26472758	Jiyoye	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-2.1535395729686053	[58]	[9]	-8	hSpCas9	negative selection	80705
57755410	57755433	16	-	26472758	Jiyoye	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	0.579128064295168	[78]	[88]	4	hSpCas9	negative selection	80706
57756376	57756399	16	-	26472758	Jiyoye	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-0.2990934154374164	[61]	[37]	-2	hSpCas9	negative selection	80707
57753457	57753480	16	-	26472758	KBM7	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-1.1836513586677473	[517,178]	[117,24]	-7	hSpCas9	negative selection	271816
57756446	57756469	16	+	26472758	KBM7	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-0.04646775644196932	[100,96]	[31,56]	0	hSpCas9	negative selection	271817
57744399	57744422	16	+	26472758	KBM7	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-0.6512665104173262	[1239,789]	[185,398]	-5	hSpCas9	negative selection	271818
57744461	57744484	16	-	26472758	KBM7	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.04044110492324626	[227,231]	[81,126]	0	hSpCas9	negative selection	271819
57752545	57752568	16	+	26472758	KBM7	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.9410121949841603	[867,434]	[49,101]	-8	hSpCas9	negative selection	271820
57753178	57753201	16	-	26472758	KBM7	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	0.08621357964533183	[1233,773]	[494,488]	0	hSpCas9	negative selection	271821
57753217	57753240	16	-	26472758	KBM7	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-1.4346121618624545	[55,95]	[10,15]	-7	hSpCas9	negative selection	271822
57754964	57754987	16	-	26472758	KBM7	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-0.322714402092219	[98,38]	[35,14]	-3	hSpCas9	negative selection	271823
57755410	57755433	16	-	26472758	KBM7	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.12511142932203148	[366,483]	[263,117]	-1	hSpCas9	negative selection	271824
57756376	57756399	16	-	26472758	KBM7	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-0.4181506666335677	[205,116]	[45,63]	-4	hSpCas9	negative selection	271825
57753457	57753480	16	-	26472758	Raji	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.21454455951376294	[159]	[31]	-2	hSpCas9	negative selection	462934
57756446	57756469	16	+	26472758	Raji	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-0.07848300993773427	[90]	[19]	0	hSpCas9	negative selection	462935
57744399	57744422	16	+	26472758	Raji	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	0.4307323049605891	[405]	[126]	4	hSpCas9	negative selection	462936
57744461	57744484	16	-	26472758	Raji	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	0.3444227326744488	[111]	[32]	3	hSpCas9	negative selection	462937
57752545	57752568	16	+	26472758	Raji	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.1418754918155305	[541]	[56]	-7	hSpCas9	negative selection	462938
57753178	57753201	16	-	26472758	Raji	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.2527408830747129	[420]	[81]	-2	hSpCas9	negative selection	462939
57753217	57753240	16	-	26472758	Raji	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	0.10738353537359946	[147]	[36]	1	hSpCas9	negative selection	462940
57754964	57754987	16	-	26472758	Raji	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	0.6923460360947558	[55]	[20]	6	hSpCas9	negative selection	462941
57755410	57755433	16	-	26472758	Raji	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	0.0020305352273708444	[141]	[32]	0	hSpCas9	negative selection	462942
57756376	57756399	16	-	26472758	Raji	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	0.007847861822684932	[59]	[13]	0	hSpCas9	negative selection	462943
57753457	57753480	16	-	26472758	K562	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-1.8915589418525276	[188]	[42]	-7	hSpCas9	negative selection	654052
57756446	57756469	16	+	26472758	K562	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-0.6101508328119896	[131]	[72]	-4	hSpCas9	negative selection	654053
57744399	57744422	16	+	26472758	K562	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	0.23850199330001454	[732]	[729]	1	hSpCas9	negative selection	654054
57744461	57744484	16	-	26472758	K562	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	0.4057817156053354	[168]	[188]	3	hSpCas9	negative selection	654055
57752545	57752568	16	+	26472758	K562	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.6102419091695137	[433]	[119]	-7	hSpCas9	negative selection	654056
57753178	57753201	16	-	26472758	K562	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.28248667146493633	[620]	[430]	-2	hSpCas9	negative selection	654057
57753217	57753240	16	-	26472758	K562	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	0.6174621382806635	[60]	[78]	5	hSpCas9	negative selection	654058
57754964	57754987	16	-	26472758	K562	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	0.829381228387603	[55]	[83]	7	hSpCas9	negative selection	654059
57755410	57755433	16	-	26472758	K562	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	0.6706834823685446	[319]	[429]	5	hSpCas9	negative selection	654060
57756376	57756399	16	-	26472758	K562	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	1.410227620636527	[155]	[349]	9	hSpCas9	negative selection	654061
57737252	57737275	16	-	26627737	DLD1	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.1679701650103442	[514]	[115,25,70]	-8	hSpCas9	negative selection	794596
57741784	57741807	16	-	26627737	DLD1	viability	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-2.4837350242322285	[248]	[16,12,11]	-9	hSpCas9	negative selection	794597
57744415	57744438	16	-	26627737	DLD1	viability	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-1.4924422826306196	[396]	[54,27,47]	-8	hSpCas9	negative selection	794598
57750876	57750899	16	-	26627737	DLD1	viability	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-1.5024888212430232	[1439]	[145,205,130]	-8	hSpCas9	negative selection	794599
57751654	57751677	16	-	26627737	DLD1	viability	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-1.8482494034533004	[155]	[39,0,0]	-8	hSpCas9	negative selection	794600
57752563	57752586	16	+	26627737	DLD1	viability	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-1.2067043174143506	[266]	[17,29,56]	-8	hSpCas9	negative selection	794601
57737252	57737275	16	-	26627737	GBM cells	viability after 5 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.05272310355291519	[263]	[138,133]	-1	hSpCas9	negative selection	876911
57741784	57741807	16	-	26627737	GBM cells	viability after 5 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-0.41303013142905476	[71]	[33,23]	-6	hSpCas9	negative selection	876912
57744415	57744438	16	-	26627737	GBM cells	viability after 5 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.11516131032603716	[102]	[44,56]	-2	hSpCas9	negative selection	876913
57750876	57750899	16	-	26627737	GBM cells	viability after 5 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	0.09396678933841673	[448]	[276,236]	1	hSpCas9	negative selection	876914
57751654	57751677	16	-	26627737	GBM cells	viability after 5 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.19014517255013152	[75]	[53,38]	3	hSpCas9	negative selection	876915
57752563	57752586	16	+	26627737	GBM cells	viability after 5 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.9130137769617428	[157]	[29,59]	-8	hSpCas9	negative selection	876916
57737252	57737275	16	-	26627737	GBM cells	viability after 13 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.5813120089773474	[263]	[119,75]	-6	hSpCas9	negative selection	959226
57741784	57741807	16	-	26627737	GBM cells	viability after 13 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-0.33670861634541494	[71]	[36,25]	-4	hSpCas9	negative selection	959227
57744415	57744438	16	-	26627737	GBM cells	viability after 13 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.4143549274854019	[102]	[47,36]	-5	hSpCas9	negative selection	959228
57750876	57750899	16	-	26627737	GBM cells	viability after 13 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	0.06480291476872413	[448]	[288,226]	0	hSpCas9	negative selection	959229
57751654	57751677	16	-	26627737	GBM cells	viability after 13 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.05846542265190213	[75]	[64,24]	0	hSpCas9	negative selection	959230
57752563	57752586	16	+	26627737	GBM cells	viability after 13 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.29892574338096567	[157]	[56,79]	-4	hSpCas9	negative selection	959231
57737252	57737275	16	-	26627737	GBM cells	viability after 21 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.2826049558437738	[263]	[59,57]	-8	hSpCas9	negative selection	1041541
57741784	57741807	16	-	26627737	GBM cells	viability after 21 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-0.02207267695349513	[71]	[37,38]	0	hSpCas9	negative selection	1041542
57744415	57744438	16	-	26627737	GBM cells	viability after 21 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	0.05585349792093619	[102]	[65,50]	0	hSpCas9	negative selection	1041543
57750876	57750899	16	-	26627737	GBM cells	viability after 21 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	0.018483114884972007	[448]	[256,237]	0	hSpCas9	negative selection	1041544
57751654	57751677	16	-	26627737	GBM cells	viability after 21 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.5711665756343374	[75]	[64,57]	6	hSpCas9	negative selection	1041545
57752563	57752586	16	+	26627737	GBM cells	viability after 21 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.3370278535303146	[157]	[68,66]	-3	hSpCas9	negative selection	1041546
57737252	57737275	16	-	26627737	RPE1	viability after 9 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.11167164663725083	[850]	[222,276]	-1	hSpCas9	negative selection	1123856
57741784	57741807	16	-	26627737	RPE1	viability after 9 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-1.1712907352646198	[544]	[80,68]	-7	hSpCas9	negative selection	1123857
57744415	57744438	16	-	26627737	RPE1	viability after 9 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.08882144933426461	[573]	[185,146]	0	hSpCas9	negative selection	1123858
57750876	57750899	16	-	26627737	RPE1	viability after 9 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.4803349161506274	[2290]	[390,672]	-3	hSpCas9	negative selection	1123859
57751654	57751677	16	-	26627737	RPE1	viability after 9 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.9941233699703291	[228]	[106,188]	6	hSpCas9	negative selection	1123860
57752563	57752586	16	+	26627737	RPE1	viability after 9 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-2.1785564261061547	[555]	[44,29]	-9	hSpCas9	negative selection	1123861
57737252	57737275	16	-	26627737	RPE1	viability after 12 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.1548122334478495	[850]	[217,191]	-1	hSpCas9	negative selection	1206171
57741784	57741807	16	-	26627737	RPE1	viability after 12 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-1.412641294466491	[544]	[37,72]	-7	hSpCas9	negative selection	1206172
57744415	57744438	16	-	26627737	RPE1	viability after 12 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.9723381076313058	[573]	[64,92]	-6	hSpCas9	negative selection	1206173
57750876	57750899	16	-	26627737	RPE1	viability after 12 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.4049180486431252	[2290]	[443,486]	-3	hSpCas9	negative selection	1206174
57751654	57751677	16	-	26627737	RPE1	viability after 12 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.4114881230662064	[228]	[37,54]	-3	hSpCas9	negative selection	1206175
57752563	57752586	16	+	26627737	RPE1	viability after 12 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-1.1530538543423148	[555]	[72,60]	-7	hSpCas9	negative selection	1206176
57737252	57737275	16	-	26627737	RPE1	viability after 15 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.11893988756995244	[850]	[295,149]	0	hSpCas9	negative selection	1288486
57741784	57741807	16	-	26627737	RPE1	viability after 15 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-2.0854412038212087	[544]	[17,53]	-8	hSpCas9	negative selection	1288487
57744415	57744438	16	-	26627737	RPE1	viability after 15 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-1.0443023839214747	[573]	[121,36]	-6	hSpCas9	negative selection	1288488
57750876	57750899	16	-	26627737	RPE1	viability after 15 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.5781006849923673	[2290]	[427,439]	-4	hSpCas9	negative selection	1288489
57751654	57751677	16	-	26627737	RPE1	viability after 15 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.4104030147697697	[228]	[136,36]	2	hSpCas9	negative selection	1288490
57752563	57752586	16	+	26627737	RPE1	viability after 15 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.9111834372072072	[555]	[47,117]	-5	hSpCas9	negative selection	1288491
57737252	57737275	16	-	26627737	RPE1	viability after 18 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	0.08225307752562515	[850]	[348,129]	0	hSpCas9	negative selection	1370801
57741784	57741807	16	-	26627737	RPE1	viability after 18 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-1.8213738171408247	[544]	[44,37]	-8	hSpCas9	negative selection	1370802
57744415	57744438	16	-	26627737	RPE1	viability after 18 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.21959641188224355	[573]	[133,131]	-1	hSpCas9	negative selection	1370803
57750876	57750899	16	-	26627737	RPE1	viability after 18 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.9950430154547537	[2290]	[315,303]	-6	hSpCas9	negative selection	1370804
57751654	57751677	16	-	26627737	RPE1	viability after 18 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.3472984274232158	[228]	[79,14]	-2	hSpCas9	negative selection	1370805
57752563	57752586	16	+	26627737	RPE1	viability after 18 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-1.8278675170160454	[555]	[49,33]	-8	hSpCas9	negative selection	1370806
57737252	57737275	16	-	26627737	HeLa	viability after 8 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.46557828980762117	[402]	[108,125,140]	-4	hSpCas9	negative selection	1453116
57741784	57741807	16	-	26627737	HeLa	viability after 8 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	2.2574722908651816	[36]	[49,171,7]	9	hSpCas9	negative selection	1453117
57744415	57744438	16	-	26627737	HeLa	viability after 8 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.00996170942237895	[173]	[69,57,94]	0	hSpCas9	negative selection	1453118
57750876	57750899	16	-	26627737	HeLa	viability after 8 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	0.5148774846717491	[518]	[347,337,289]	4	hSpCas9	negative selection	1453119
57751654	57751677	16	-	26627737	HeLa	viability after 8 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.029273189897380147	[119]	[131,3,41]	0	hSpCas9	negative selection	1453120
57752563	57752586	16	+	26627737	HeLa	viability after 8 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.09111011372053218	[309]	[117,73,181]	-1	hSpCas9	negative selection	1453121
57737252	57737275	16	-	26627737	HeLa	viability after 12 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.8105584802492749	[402]	[31,151,92]	-6	hSpCas9	negative selection	1535431
57741784	57741807	16	-	26627737	HeLa	viability after 12 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	0.5657184630140102	[36]	[1,15,49]	5	hSpCas9	negative selection	1535432
57744415	57744438	16	-	26627737	HeLa	viability after 12 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	0.4502587435970661	[173]	[82,34,182]	4	hSpCas9	negative selection	1535433
57750876	57750899	16	-	26627737	HeLa	viability after 12 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.14443901442403506	[518]	[173,189,217]	-1	hSpCas9	negative selection	1535434
57751654	57751677	16	-	26627737	HeLa	viability after 12 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	1.3590826772736735	[119]	[230,123,29]	8	hSpCas9	negative selection	1535435
57752563	57752586	16	+	26627737	HeLa	viability after 12 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.7669143981047017	[309]	[141,63,22]	-6	hSpCas9	negative selection	1535436
57737252	57737275	16	-	26627737	HeLa	viability after 15 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.443322032205217	[402]	[50,58,71]	-8	hSpCas9	negative selection	1617746
57741784	57741807	16	-	26627737	HeLa	viability after 15 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	2.2856678356110756	[36]	[67,107,41]	9	hSpCas9	negative selection	1617747
57744415	57744438	16	-	26627737	HeLa	viability after 15 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.1698216926995335	[173]	[72,25,91]	-1	hSpCas9	negative selection	1617748
57750876	57750899	16	-	26627737	HeLa	viability after 15 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.2871204867260059	[518]	[112,224,182]	-2	hSpCas9	negative selection	1617749
57751654	57751677	16	-	26627737	HeLa	viability after 15 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.24224649522965347	[119]	[74,53,42]	2	hSpCas9	negative selection	1617750
57752563	57752586	16	+	26627737	HeLa	viability after 15 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.8587888842660241	[309]	[101,40,64]	-6	hSpCas9	negative selection	1617751
57737252	57737275	16	-	26627737	HeLa	viability after 18 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.4972067805757012	[402]	[32,44,71]	-8	hSpCas9	negative selection	1700061
57741784	57741807	16	-	26627737	HeLa	viability after 18 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	2.3626755270966804	[36]	[52,89,41]	9	hSpCas9	negative selection	1700062
57744415	57744438	16	-	26627737	HeLa	viability after 18 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.15579803491853594	[173]	[48,22,91]	-1	hSpCas9	negative selection	1700063
57750876	57750899	16	-	26627737	HeLa	viability after 18 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.2977131297713119	[518]	[75,182,182]	-3	hSpCas9	negative selection	1700064
57751654	57751677	16	-	26627737	HeLa	viability after 18 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.3427187663963658	[119]	[54,48,42]	3	hSpCas9	negative selection	1700065
57752563	57752586	16	+	26627737	HeLa	viability after 18 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.8481483227233144	[309]	[66,36,64]	-6	hSpCas9	negative selection	1700066
57737252	57737275	16	-	26627737	HCT116	viability after 6 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	0.872087177955988	[267]	[60,85]	5	hSpCas9	negative selection	1782376
57741784	57741807	16	-	26627737	HCT116	viability after 6 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-0.8228134178507229	[92]	[15,3]	-5	hSpCas9	negative selection	1782377
57744415	57744438	16	-	26627737	HCT116	viability after 6 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-4.0974357979597285	[224]	[3,0]	-9	hSpCas9	negative selection	1782378
57750876	57750899	16	-	26627737	HCT116	viability after 6 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	1.049300074553166	[1140]	[532,281]	5	hSpCas9	negative selection	1782379
57751654	57751677	16	-	26627737	HCT116	viability after 6 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.9856370084936392	[381]	[68,8]	-5	hSpCas9	negative selection	1782380
57752563	57752586	16	+	26627737	HCT116	viability after 6 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	0.9011452996393176	[652]	[27,281]	5	hSpCas9	negative selection	1782381
57737252	57737275	16	-	26627737	HCT116	viability after 8 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.31721387947700547	[360]	[178,196,103]	-4	hSpCas9	negative selection	1864691
57741784	57741807	16	-	26627737	HCT116	viability after 8 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-0.019201574402350374	[112]	[61,32,88]	0	hSpCas9	negative selection	1864692
57744415	57744438	16	-	26627737	HCT116	viability after 8 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.16973011907758884	[178]	[63,140,57]	-2	hSpCas9	negative selection	1864693
57750876	57750899	16	-	26627737	HCT116	viability after 8 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.14372088366951985	[720]	[239,334,499]	-2	hSpCas9	negative selection	1864694
57751654	57751677	16	-	26627737	HCT116	viability after 8 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.2519981993585916	[236]	[72,117,136]	-3	hSpCas9	negative selection	1864695
57752563	57752586	16	+	26627737	HCT116	viability after 8 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.2531990194204667	[237]	[107,188,33]	-3	hSpCas9	negative selection	1864696
57737252	57737275	16	-	26627737	HCT116	viability after 9 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	0.9817666101135877	[267]	[80,188]	6	hSpCas9	negative selection	1947006
57741784	57741807	16	-	26627737	HCT116	viability after 9 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	1.454631173947523	[92]	[14,109]	8	hSpCas9	negative selection	1947007
57744415	57744438	16	-	26627737	HCT116	viability after 9 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	0.6455209080174032	[224]	[117,74]	5	hSpCas9	negative selection	1947008
57750876	57750899	16	-	26627737	HCT116	viability after 9 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	0.5386312874984788	[1140]	[441,442]	4	hSpCas9	negative selection	1947009
57751654	57751677	16	-	26627737	HCT116	viability after 9 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.5124809896329975	[381]	[92,186]	4	hSpCas9	negative selection	1947010
57752563	57752586	16	+	26627737	HCT116	viability after 9 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-1.7256511824045813	[652]	[21,76]	-8	hSpCas9	negative selection	1947011
57737252	57737275	16	-	26627737	HCT116	viability after 12 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.2282249460270201	[360]	[139,128,217]	-2	hSpCas9	negative selection	2029321
57741784	57741807	16	-	26627737	HCT116	viability after 12 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	0.1592712446889828	[112]	[30,22,146]	1	hSpCas9	negative selection	2029322
57744415	57744438	16	-	26627737	HCT116	viability after 12 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.03752194424274313	[178]	[63,157,56]	0	hSpCas9	negative selection	2029323
57750876	57750899	16	-	26627737	HCT116	viability after 12 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.29344581730379515	[720]	[214,400,321]	-3	hSpCas9	negative selection	2029324
57751654	57751677	16	-	26627737	HCT116	viability after 12 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.8294783492674931	[236]	[56,52,100]	-7	hSpCas9	negative selection	2029325
57752563	57752586	16	+	26627737	HCT116	viability after 12 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.359943433089787	[237]	[91,185,16]	-4	hSpCas9	negative selection	2029326
57737252	57737275	16	-	26627737	HCT116	viability after 15 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.48776619993946546	[360]	[124,187,127]	-5	hSpCas9	negative selection	2111636
57741784	57741807	16	-	26627737	HCT116	viability after 15 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	0.05026984262641854	[112]	[92,66,44]	0	hSpCas9	negative selection	2111637
57744415	57744438	16	-	26627737	HCT116	viability after 15 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.3078908438390776	[178]	[92,128,28]	-3	hSpCas9	negative selection	2111638
57750876	57750899	16	-	26627737	HCT116	viability after 15 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.13540921971107833	[720]	[192,494,419]	-1	hSpCas9	negative selection	2111639
57751654	57751677	16	-	26627737	HCT116	viability after 15 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-1.6740903358931658	[236]	[58,32,37]	-9	hSpCas9	negative selection	2111640
57752563	57752586	16	+	26627737	HCT116	viability after 15 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.6000747771833188	[237]	[77,180,10]	-6	hSpCas9	negative selection	2111641
57737252	57737275	16	-	26627737	HCT116	viability after 18 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.024877193981472	[360]	[69,34,158]	-7	hSpCas9	negative selection	2193951
57741784	57741807	16	-	26627737	HCT116	viability after 18 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-1.0126080106445812	[112]	[27,2,52]	-7	hSpCas9	negative selection	2193952
57744415	57744438	16	-	26627737	HCT116	viability after 18 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.0958529667949205	[178]	[26,170,36]	-1	hSpCas9	negative selection	2193953
57750876	57750899	16	-	26627737	HCT116	viability after 18 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.0829725276388773	[720]	[98,519,356]	0	hSpCas9	negative selection	2193954
57751654	57751677	16	-	26627737	HCT116	viability after 18 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-2.690682276777115	[236]	[0,0,53]	-9	hSpCas9	negative selection	2193955
57752563	57752586	16	+	26627737	HCT116	viability after 18 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.6641456903502698	[237]	[27,157,23]	-6	hSpCas9	negative selection	2193956
57737252	57737275	16	-	24336569	HL60	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.10189600053370962	[319]	[630]	-1	hSpCas9	negative selection	2272738
57737263	57737286	16	-	24336569	HL60	viability	ACGCAACTTCCAGGCTGTCTTGG	KATNB1	ENSG00000140854	1.0580480486329569	[1304]	[5749]	7	hSpCas9	negative selection	2272739
57737272	57737295	16	-	24336569	HL60	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.4526573555506168	[798]	[2313]	4	hSpCas9	negative selection	2272740
57741703	57741726	16	+	24336569	HL60	viability	TGCCAGCAACGTGTCCTCACTGG	KATNB1	ENSG00000140854	0.6277160205558863	[518]	[1696]	5	hSpCas9	negative selection	2272741
57741709	57741732	16	+	24336569	HL60	viability	CAACGTGTCCTCACTGGTGCTGG	KATNB1	ENSG00000140854	0.5966078044837413	[179]	[575]	5	hSpCas9	negative selection	2272742
57741717	57741740	16	-	24336569	HL60	viability	GGCTTTGCCCAGCACCAGTGAGG	KATNB1	ENSG00000140854	-0.9485698301315509	[683]	[749]	-7	hSpCas9	negative selection	2272743
57741722	57741745	16	+	24336569	HL60	viability	CTGGTGCTGGGCAAAGCCTCCGG	KATNB1	ENSG00000140854	0.6967897020279417	[371]	[1275]	6	hSpCas9	negative selection	2272744
57741733	57741756	16	+	24336569	HL60	viability	CAAAGCCTCCGGGCGGCTGCTGG	KATNB1	ENSG00000140854	0.8703198308395238	[250]	[970]	7	hSpCas9	negative selection	2272745
57741738	57741761	16	-	24336569	HL60	viability	TGTAGCCAGCAGCCGCCCGGAGG	KATNB1	ENSG00000140854	-1.1205242202171857	[598]	[582]	-7	hSpCas9	negative selection	2272746
57741743	57741766	16	+	24336569	HL60	viability	GGGCGGCTGCTGGCTACAGGCGG	KATNB1	ENSG00000140854	-0.26203634627071715	[220]	[389]	-2	hSpCas9	negative selection	2272747
57737252	57737275	16	-	24336569	KBM7	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.4800006742412599	[269]	[527]	-4	hSpCas9	negative selection	2339915
57737263	57737286	16	-	24336569	KBM7	viability	ACGCAACTTCCAGGCTGTCTTGG	KATNB1	ENSG00000140854	-0.043433927998273836	[1046]	[2770]	0	hSpCas9	negative selection	2339916
57737272	57737295	16	-	24336569	KBM7	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6022454399704258	[682]	[2827]	5	hSpCas9	negative selection	2339917
57741703	57741726	16	+	24336569	KBM7	viability	TGCCAGCAACGTGTCCTCACTGG	KATNB1	ENSG00000140854	-0.012606659216986171	[556]	[1505]	0	hSpCas9	negative selection	2339918
57741709	57741732	16	+	24336569	KBM7	viability	CAACGTGTCCTCACTGGTGCTGG	KATNB1	ENSG00000140854	-1.1576727747120459	[327]	[400]	-7	hSpCas9	negative selection	2339919
57741717	57741740	16	-	24336569	KBM7	viability	GGCTTTGCCCAGCACCAGTGAGG	KATNB1	ENSG00000140854	0.4012792776882208	[278]	[1004]	4	hSpCas9	negative selection	2339920
57741722	57741745	16	+	24336569	KBM7	viability	CTGGTGCTGGGCAAAGCCTCCGG	KATNB1	ENSG00000140854	-0.44339948805059143	[516]	[1036]	-4	hSpCas9	negative selection	2339921
57741733	57741756	16	+	24336569	KBM7	viability	CAAAGCCTCCGGGCGGCTGCTGG	KATNB1	ENSG00000140854	-0.04079641183184968	[240]	[638]	0	hSpCas9	negative selection	2339922
57741738	57741761	16	-	24336569	KBM7	viability	TGTAGCCAGCAGCCGCCCGGAGG	KATNB1	ENSG00000140854	-1.245620367466857	[385]	[443]	-7	hSpCas9	negative selection	2339923
57741743	57741766	16	+	24336569	KBM7	viability	GGGCGGCTGCTGGCTACAGGCGG	KATNB1	ENSG00000140854	-0.1521233130227111	[208]	[512]	-1	hSpCas9	negative selection	2339924
57741717	57741740	16	-	27260157	DLD1	viability	GGCTTTGCCCAGCACCAGTGAGG	KATNB1	ENSG00000140854	-1.83279892898873	[]	[]	-8	hSpCas9	negative selection	2579807
57744413	57744436	16	-	27260157	DLD1	viability	GAGGCGGACGCTCTCCACTGGGG	KATNB1	ENSG00000140854	0.653968949201481	[]	[]	8	hSpCas9	negative selection	2580765
57741803	57741826	16	-	27260157	DLD1	viability	GGGCTCACCATGATGCAGTTGGG	KATNB1	ENSG00000140854	-0.146011581720191	[]	[]	-1	hSpCas9	negative selection	2583181
57744470	57744493	16	+	27260157	DLD1	viability	AGTCGGGCTCCATCCGTGTCTGG	KATNB1	ENSG00000140854	-0.989409881963342	[]	[]	-7	hSpCas9	negative selection	2584128
57750867	57750890	16	-	27260157	DLD1	viability	CGCCGTACGGGTGGAAATCCAGG	KATNB1	ENSG00000140854	-1.36814035744868	[]	[]	-8	hSpCas9	negative selection	2587325
57737263	57737286	16	-	27260157	DLD1	viability	ACGCAACTTCCAGGCTGTCTTGG	KATNB1	ENSG00000140854	-0.584324351787831	[]	[]	-5	hSpCas9	negative selection	2604543
57741733	57741756	16	+	27260157	DLD1	viability	CAAAGCCTCCGGGCGGCTGCTGG	KATNB1	ENSG00000140854	0.764492630834488	[]	[]	8	hSpCas9	negative selection	2604604
57751293	57751316	16	-	27260157	DLD1	viability	AGCGCATCCTTACCCTGTATCGG	KATNB1	ENSG00000140854	-2.18316266753482	[]	[]	-9	hSpCas9	negative selection	2606367
57741738	57741761	16	-	27260157	DLD1	viability	TGTAGCCAGCAGCCGCCCGGAGG	KATNB1	ENSG00000140854	-1.13122102049014	[]	[]	-7	hSpCas9	negative selection	2612083
57741768	57741791	16	+	27260157	DLD1	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.102671658012354	[]	[]	0	hSpCas9	negative selection	2612617
57741709	57741732	16	+	27260157	DLD1	viability	CAACGTGTCCTCACTGGTGCTGG	KATNB1	ENSG00000140854	0.155834707751702	[]	[]	3	hSpCas9	negative selection	2613057
57741792	57741815	16	-	27260157	DLD1	viability	GATGCAGTTGGGCTTGTTGATGG	KATNB1	ENSG00000140854	0.0662546791974983	[]	[]	3	hSpCas9	negative selection	2615585
57750883	57750906	16	+	27260157	DLD1	viability	TACGGCGAGTTTGTAGCCTCTGG	KATNB1	ENSG00000140854	-0.887800055347386	[]	[]	-6	hSpCas9	negative selection	2615627
57750822	57750845	16	+	27260157	DLD1	viability	GTTAGTTCTTCGCACACTCATGG	KATNB1	ENSG00000140854	-1.18552405549199	[]	[]	-7	hSpCas9	negative selection	2619125
57737272	57737295	16	-	27260157	DLD1	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	-0.482003344144686	[]	[]	-4	hSpCas9	negative selection	2621409
57741722	57741745	16	+	27260157	DLD1	viability	CTGGTGCTGGGCAAAGCCTCCGG	KATNB1	ENSG00000140854	-1.46157167284982	[]	[]	-8	hSpCas9	negative selection	2622575
57741703	57741726	16	+	27260157	DLD1	viability	TGCCAGCAACGTGTCCTCACTGG	KATNB1	ENSG00000140854	-0.333026634139929	[]	[]	-3	hSpCas9	negative selection	2646786
57737252	57737275	16	-	27260157	DLD1	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.33019198500706	[]	[]	-7	hSpCas9	negative selection	2647688
57750879	57750902	16	-	27260157	DLD1	viability	AGGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-1.11570584395496	[]	[]	-7	hSpCas9	negative selection	2647729
57741743	57741766	16	+	27260157	DLD1	viability	GGGCGGCTGCTGGCTACAGGCGG	KATNB1	ENSG00000140854	-0.667431592230005	[]	[]	-5	hSpCas9	negative selection	2648676
57741717	57741740	16	-	27260157	HT1080	viability	GGCTTTGCCCAGCACCAGTGAGG	KATNB1	ENSG00000140854	-1.23639839439616	[]	[]	-9	hSpCas9	negative selection	2655937
57744413	57744436	16	-	27260157	HT1080	viability	GAGGCGGACGCTCTCCACTGGGG	KATNB1	ENSG00000140854	-1.25003509941242	[]	[]	-9	hSpCas9	negative selection	2656895
57741803	57741826	16	-	27260157	HT1080	viability	GGGCTCACCATGATGCAGTTGGG	KATNB1	ENSG00000140854	0.0734576717125107	[]	[]	0	hSpCas9	negative selection	2659311
57744470	57744493	16	+	27260157	HT1080	viability	AGTCGGGCTCCATCCGTGTCTGG	KATNB1	ENSG00000140854	-0.222075836661409	[]	[]	0	hSpCas9	negative selection	2660258
57750867	57750890	16	-	27260157	HT1080	viability	CGCCGTACGGGTGGAAATCCAGG	KATNB1	ENSG00000140854	-1.16014270732138	[]	[]	-8	hSpCas9	negative selection	2663455
57737263	57737286	16	-	27260157	HT1080	viability	ACGCAACTTCCAGGCTGTCTTGG	KATNB1	ENSG00000140854	0.673661359549579	[]	[]	6	hSpCas9	negative selection	2680673
57741733	57741756	16	+	27260157	HT1080	viability	CAAAGCCTCCGGGCGGCTGCTGG	KATNB1	ENSG00000140854	0.701121858355138	[]	[]	6	hSpCas9	negative selection	2680734
57751293	57751316	16	-	27260157	HT1080	viability	AGCGCATCCTTACCCTGTATCGG	KATNB1	ENSG00000140854	-1.04860128106945	[]	[]	-8	hSpCas9	negative selection	2682497
57741738	57741761	16	-	27260157	HT1080	viability	TGTAGCCAGCAGCCGCCCGGAGG	KATNB1	ENSG00000140854	-0.628310427499483	[]	[]	-8	hSpCas9	negative selection	2688213
57741768	57741791	16	+	27260157	HT1080	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.0365749517113742	[]	[]	0	hSpCas9	negative selection	2688747
57741709	57741732	16	+	27260157	HT1080	viability	CAACGTGTCCTCACTGGTGCTGG	KATNB1	ENSG00000140854	0.210149965201759	[]	[]	2	hSpCas9	negative selection	2689187
57741792	57741815	16	-	27260157	HT1080	viability	GATGCAGTTGGGCTTGTTGATGG	KATNB1	ENSG00000140854	-0.780013290768577	[]	[]	-8	hSpCas9	negative selection	2691715
57750883	57750906	16	+	27260157	HT1080	viability	TACGGCGAGTTTGTAGCCTCTGG	KATNB1	ENSG00000140854	-0.298269268452377	[]	[]	-7	hSpCas9	negative selection	2691757
57750822	57750845	16	+	27260157	HT1080	viability	GTTAGTTCTTCGCACACTCATGG	KATNB1	ENSG00000140854	-0.676331856959562	[]	[]	-8	hSpCas9	negative selection	2695255
57737272	57737295	16	-	27260157	HT1080	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.978061562178351	[]	[]	7	hSpCas9	negative selection	2697539
57741722	57741745	16	+	27260157	HT1080	viability	CTGGTGCTGGGCAAAGCCTCCGG	KATNB1	ENSG00000140854	-0.270342547531408	[]	[]	-4	hSpCas9	negative selection	2698705
57741703	57741726	16	+	27260157	HT1080	viability	TGCCAGCAACGTGTCCTCACTGG	KATNB1	ENSG00000140854	-0.249929531414081	[]	[]	0	hSpCas9	negative selection	2722916
57737252	57737275	16	-	27260157	HT1080	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.24110177621684	[]	[]	-9	hSpCas9	negative selection	2723818
57750879	57750902	16	-	27260157	HT1080	viability	AGGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-1.45908897612713	[]	[]	-9	hSpCas9	negative selection	2723859
57741743	57741766	16	+	27260157	HT1080	viability	GGGCGGCTGCTGGCTACAGGCGG	KATNB1	ENSG00000140854	-0.34053780440427	[]	[]	-7	hSpCas9	negative selection	2724806
57741717	57741740	16	-	27260157	MKN45	viability	GGCTTTGCCCAGCACCAGTGAGG	KATNB1	ENSG00000140854	-1.16420128906587	[]	[]	-8	hSpCas9	negative selection	2732067
57744413	57744436	16	-	27260157	MKN45	viability	GAGGCGGACGCTCTCCACTGGGG	KATNB1	ENSG00000140854	-2.12087412356049	[]	[]	-9	hSpCas9	negative selection	2733025
57741803	57741826	16	-	27260157	MKN45	viability	GGGCTCACCATGATGCAGTTGGG	KATNB1	ENSG00000140854	-0.30249652712422	[]	[]	-1	hSpCas9	negative selection	2735441
57744470	57744493	16	+	27260157	MKN45	viability	AGTCGGGCTCCATCCGTGTCTGG	KATNB1	ENSG00000140854	-0.756167465943689	[]	[]	-7	hSpCas9	negative selection	2736388
57750867	57750890	16	-	27260157	MKN45	viability	CGCCGTACGGGTGGAAATCCAGG	KATNB1	ENSG00000140854	-2.47179560358174	[]	[]	-9	hSpCas9	negative selection	2739585
57737263	57737286	16	-	27260157	MKN45	viability	ACGCAACTTCCAGGCTGTCTTGG	KATNB1	ENSG00000140854	0.200241324529067	[]	[]	5	hSpCas9	negative selection	2756803
57741733	57741756	16	+	27260157	MKN45	viability	CAAAGCCTCCGGGCGGCTGCTGG	KATNB1	ENSG00000140854	0.911576214842844	[]	[]	8	hSpCas9	negative selection	2756864
57751293	57751316	16	-	27260157	MKN45	viability	AGCGCATCCTTACCCTGTATCGG	KATNB1	ENSG00000140854	-0.419999934668063	[]	[]	-6	hSpCas9	negative selection	2758627
57741738	57741761	16	-	27260157	MKN45	viability	TGTAGCCAGCAGCCGCCCGGAGG	KATNB1	ENSG00000140854	-0.541261466452927	[]	[]	-6	hSpCas9	negative selection	2764343
57741768	57741791	16	+	27260157	MKN45	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.894873111651118	[]	[]	-7	hSpCas9	negative selection	2764877
57741709	57741732	16	+	27260157	MKN45	viability	CAACGTGTCCTCACTGGTGCTGG	KATNB1	ENSG00000140854	0.17321430310947	[]	[]	5	hSpCas9	negative selection	2765317
57741792	57741815	16	-	27260157	MKN45	viability	GATGCAGTTGGGCTTGTTGATGG	KATNB1	ENSG00000140854	-0.652524159318031	[]	[]	-7	hSpCas9	negative selection	2767845
57750883	57750906	16	+	27260157	MKN45	viability	TACGGCGAGTTTGTAGCCTCTGG	KATNB1	ENSG00000140854	-1.34940447207142	[]	[]	-8	hSpCas9	negative selection	2767887
57750822	57750845	16	+	27260157	MKN45	viability	GTTAGTTCTTCGCACACTCATGG	KATNB1	ENSG00000140854	-1.68945523029607	[]	[]	-9	hSpCas9	negative selection	2771385
57737272	57737295	16	-	27260157	MKN45	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	-0.523886186358457	[]	[]	-6	hSpCas9	negative selection	2773669
57741722	57741745	16	+	27260157	MKN45	viability	CTGGTGCTGGGCAAAGCCTCCGG	KATNB1	ENSG00000140854	0.39597928962309	[]	[]	6	hSpCas9	negative selection	2774835
57741703	57741726	16	+	27260157	MKN45	viability	TGCCAGCAACGTGTCCTCACTGG	KATNB1	ENSG00000140854	-0.816205044419769	[]	[]	-7	hSpCas9	negative selection	2799046
57737252	57737275	16	-	27260157	MKN45	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.43238207558516	[]	[]	-6	hSpCas9	negative selection	2799948
57750879	57750902	16	-	27260157	MKN45	viability	AGGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-2.97737488776817	[]	[]	-9	hSpCas9	negative selection	2799989
57741743	57741766	16	+	27260157	MKN45	viability	GGGCGGCTGCTGGCTACAGGCGG	KATNB1	ENSG00000140854	-0.336364155628284	[]	[]	-1	hSpCas9	negative selection	2800936
57741717	57741740	16	-	27260157	RKO	viability	GGCTTTGCCCAGCACCAGTGAGG	KATNB1	ENSG00000140854	-1.42953744125995	[]	[]	-8	hSpCas9	negative selection	2808197
57744413	57744436	16	-	27260157	RKO	viability	GAGGCGGACGCTCTCCACTGGGG	KATNB1	ENSG00000140854	-1.00934813709513	[]	[]	-8	hSpCas9	negative selection	2809155
57741803	57741826	16	-	27260157	RKO	viability	GGGCTCACCATGATGCAGTTGGG	KATNB1	ENSG00000140854	-0.0458452284693711	[]	[]	0	hSpCas9	negative selection	2811571
57744470	57744493	16	+	27260157	RKO	viability	AGTCGGGCTCCATCCGTGTCTGG	KATNB1	ENSG00000140854	-0.641460762318947	[]	[]	-7	hSpCas9	negative selection	2812518
57750867	57750890	16	-	27260157	RKO	viability	CGCCGTACGGGTGGAAATCCAGG	KATNB1	ENSG00000140854	-2.22301074824131	[]	[]	-9	hSpCas9	negative selection	2815715
57737263	57737286	16	-	27260157	RKO	viability	ACGCAACTTCCAGGCTGTCTTGG	KATNB1	ENSG00000140854	0.0256267085897842	[]	[]	0	hSpCas9	negative selection	2832933
57741733	57741756	16	+	27260157	RKO	viability	CAAAGCCTCCGGGCGGCTGCTGG	KATNB1	ENSG00000140854	0.627078542179511	[]	[]	3	hSpCas9	negative selection	2832994
57751293	57751316	16	-	27260157	RKO	viability	AGCGCATCCTTACCCTGTATCGG	KATNB1	ENSG00000140854	-2.18072756115941	[]	[]	-9	hSpCas9	negative selection	2834757
57741738	57741761	16	-	27260157	RKO	viability	TGTAGCCAGCAGCCGCCCGGAGG	KATNB1	ENSG00000140854	-0.766122130236672	[]	[]	-7	hSpCas9	negative selection	2840473
57741768	57741791	16	+	27260157	RKO	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.478879382611395	[]	[]	-6	hSpCas9	negative selection	2841007
57741709	57741732	16	+	27260157	RKO	viability	CAACGTGTCCTCACTGGTGCTGG	KATNB1	ENSG00000140854	0.407764219632499	[]	[]	2	hSpCas9	negative selection	2841447
57741792	57741815	16	-	27260157	RKO	viability	GATGCAGTTGGGCTTGTTGATGG	KATNB1	ENSG00000140854	-0.478908824595035	[]	[]	-6	hSpCas9	negative selection	2843975
57750883	57750906	16	+	27260157	RKO	viability	TACGGCGAGTTTGTAGCCTCTGG	KATNB1	ENSG00000140854	-0.438459117982181	[]	[]	-6	hSpCas9	negative selection	2844017
57750822	57750845	16	+	27260157	RKO	viability	GTTAGTTCTTCGCACACTCATGG	KATNB1	ENSG00000140854	-1.46969271217183	[]	[]	-8	hSpCas9	negative selection	2847515
57737272	57737295	16	-	27260157	RKO	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	-0.237571984910198	[]	[]	-1	hSpCas9	negative selection	2849799
57741722	57741745	16	+	27260157	RKO	viability	CTGGTGCTGGGCAAAGCCTCCGG	KATNB1	ENSG00000140854	-1.09046498466011	[]	[]	-8	hSpCas9	negative selection	2850965
57741703	57741726	16	+	27260157	RKO	viability	TGCCAGCAACGTGTCCTCACTGG	KATNB1	ENSG00000140854	-0.824810821531868	[]	[]	-7	hSpCas9	negative selection	2875176
57737252	57737275	16	-	27260157	RKO	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-1.04196358137899	[]	[]	-8	hSpCas9	negative selection	2876078
57750879	57750902	16	-	27260157	RKO	viability	AGGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-1.47552161238768	[]	[]	-8	hSpCas9	negative selection	2876119
57741743	57741766	16	+	27260157	RKO	viability	GGGCGGCTGCTGGCTACAGGCGG	KATNB1	ENSG00000140854	-1.21263124826783	[]	[]	-8	hSpCas9	negative selection	2877066
57741717	57741740	16	-	27260157	SF268	viability	GGCTTTGCCCAGCACCAGTGAGG	KATNB1	ENSG00000140854	-0.403013087207616	[]	[]	-3	hSpCas9	negative selection	2884327
57744413	57744436	16	-	27260157	SF268	viability	GAGGCGGACGCTCTCCACTGGGG	KATNB1	ENSG00000140854	-0.978963544389544	[]	[]	-7	hSpCas9	negative selection	2885285
57741803	57741826	16	-	27260157	SF268	viability	GGGCTCACCATGATGCAGTTGGG	KATNB1	ENSG00000140854	-0.0575153326750334	[]	[]	0	hSpCas9	negative selection	2887701
57744470	57744493	16	+	27260157	SF268	viability	AGTCGGGCTCCATCCGTGTCTGG	KATNB1	ENSG00000140854	-0.0981651295738591	[]	[]	-1	hSpCas9	negative selection	2888648
57750867	57750890	16	-	27260157	SF268	viability	CGCCGTACGGGTGGAAATCCAGG	KATNB1	ENSG00000140854	-3.40261900369442	[]	[]	-9	hSpCas9	negative selection	2891845
57737263	57737286	16	-	27260157	SF268	viability	ACGCAACTTCCAGGCTGTCTTGG	KATNB1	ENSG00000140854	0.732786777227643	[]	[]	8	hSpCas9	negative selection	2909063
57741733	57741756	16	+	27260157	SF268	viability	CAAAGCCTCCGGGCGGCTGCTGG	KATNB1	ENSG00000140854	0.0607835116115199	[]	[]	0	hSpCas9	negative selection	2909124
57751293	57751316	16	-	27260157	SF268	viability	AGCGCATCCTTACCCTGTATCGG	KATNB1	ENSG00000140854	-1.31747757062087	[]	[]	-7	hSpCas9	negative selection	2910887
57741738	57741761	16	-	27260157	SF268	viability	TGTAGCCAGCAGCCGCCCGGAGG	KATNB1	ENSG00000140854	-0.392518616347403	[]	[]	-3	hSpCas9	negative selection	2916603
57741768	57741791	16	+	27260157	SF268	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.271074182313938	[]	[]	4	hSpCas9	negative selection	2917137
57741709	57741732	16	+	27260157	SF268	viability	CAACGTGTCCTCACTGGTGCTGG	KATNB1	ENSG00000140854	0.414113773390358	[]	[]	4	hSpCas9	negative selection	2917577
57741792	57741815	16	-	27260157	SF268	viability	GATGCAGTTGGGCTTGTTGATGG	KATNB1	ENSG00000140854	-0.761845755009208	[]	[]	-6	hSpCas9	negative selection	2920105
57750883	57750906	16	+	27260157	SF268	viability	TACGGCGAGTTTGTAGCCTCTGG	KATNB1	ENSG00000140854	0.0811345031884687	[]	[]	0	hSpCas9	negative selection	2920147
57750822	57750845	16	+	27260157	SF268	viability	GTTAGTTCTTCGCACACTCATGG	KATNB1	ENSG00000140854	-0.690717664618933	[]	[]	-5	hSpCas9	negative selection	2923645
57737272	57737295	16	-	27260157	SF268	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.597760397952066	[]	[]	8	hSpCas9	negative selection	2925929
57741722	57741745	16	+	27260157	SF268	viability	CTGGTGCTGGGCAAAGCCTCCGG	KATNB1	ENSG00000140854	0.221024865029098	[]	[]	3	hSpCas9	negative selection	2927095
57741703	57741726	16	+	27260157	SF268	viability	TGCCAGCAACGTGTCCTCACTGG	KATNB1	ENSG00000140854	0.56420739700144	[]	[]	8	hSpCas9	negative selection	2951306
57737252	57737275	16	-	27260157	SF268	viability	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.0307786613107467	[]	[]	0	hSpCas9	negative selection	2952208
57750879	57750902	16	-	27260157	SF268	viability	AGGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-1.41321036127204	[]	[]	-8	hSpCas9	negative selection	2952249
57741743	57741766	16	+	27260157	SF268	viability	GGGCGGCTGCTGGCTACAGGCGG	KATNB1	ENSG00000140854	0.126622961045664	[]	[]	0	hSpCas9	negative selection	2953196
57752798	57752821	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GACGGCTGCTGCCTGTACAGCGG	KATNB1	ENSG00000140854	-0.15452759165390811	[3,3]	[0,3]	-2	hSpCas9	positive selection	2996550
57751654	57751677	16	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.31077707532344473	[2,2]	[1,1]	-4	hSpCas9	positive selection	2996551
57752546	57752569	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-0.8320162124330224	[2,2]	[1,0]	-8	hSpCas9	positive selection	2996552
57741727	57741750	16	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCTGGGCAAAGCCTCCGGGCGG	KATNB1	ENSG00000140854	0.04794411300850167	[2,3]	[1,3]	1	hSpCas9	positive selection	2996553
57752798	57752821	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GACGGCTGCTGCCTGTACAGCGG	KATNB1	ENSG00000140854	-1.0706863512073992	[3,3]	[1,0]	-9	hSpCas9	positive selection	3064408
57751654	57751677	16	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.6277337181644835	[2,2]	[1,0]	-8	hSpCas9	positive selection	3064409
57752546	57752569	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.0165723972550458	[2,2]	[0,0]	-9	hSpCas9	positive selection	3064410
57741727	57741750	16	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCTGGGCAAAGCCTCCGGGCGG	KATNB1	ENSG00000140854	-0.6020636317485246	[2,2]	[1,0]	-8	hSpCas9	positive selection	3064411
57737272	57737295		-	24336571	A375	resistance to PLX after 7 days	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	-0.20218095807339487	[8,7]	[6,7]	-6	hSpCas9	positive selection	3122170
57741768	57741791		+	24336571	A375	resistance to PLX after 7 days	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.00974112638961061	[9,10]	[9,10]	0	hSpCas9	positive selection	3122171
57741804	57741827		-	24336571	A375	resistance to PLX after 7 days	GGGGCTCACCATGATGCAGTTGG	KATNB1	ENSG00000140854	-0.5290973382964397	[21,18]	[14,12]	-9	hSpCas9	positive selection	3122173
57737272	57737295		-	24336571	A375	resistance to PLX after 14 days	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6013209380606584	[6,3]	[3,2]	5	hSpCas9	positive selection	3179963
57741768	57741791		+	24336571	A375	resistance to PLX after 14 days	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.9120061349531037	[4,5]	[3,4]	7	hSpCas9	positive selection	3179964
57741804	57741827		-	24336571	A375	resistance to PLX after 14 days	GGGGCTCACCATGATGCAGTTGG	KATNB1	ENSG00000140854	-0.9497010838002664	[25,17]	[4,4]	-9	hSpCas9	positive selection	3179966
57737272	57737295		-	24336571	A375	viability after 7 days	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	-0.5236764382753901	[12]	[8,7]	-6	hSpCas9	negative selection	3237756
57741768	57741791		+	24336571	A375	viability after 7 days	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.792251793511549	[19]	[9,10]	-8	hSpCas9	negative selection	3237757
57741804	57741827		-	24336571	A375	viability after 7 days	GGGGCTCACCATGATGCAGTTGG	KATNB1	ENSG00000140854	0.7849047603827194	[12]	[21,18]	9	hSpCas9	negative selection	3237759
57737272	57737295		-	24336571	A375	viability after 14 days	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	-1.1773892580574294	[12]	[6,3]	-9	hSpCas9	negative selection	3295549
57741768	57741791		+	24336571	A375	viability after 14 days	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-1.731040988561666	[19]	[4,5]	-9	hSpCas9	negative selection	3295550
57741804	57741827		-	24336571	A375	viability after 14 days	GGGGCTCACCATGATGCAGTTGG	KATNB1	ENSG00000140854	0.8750893000684544	[12]	[25,17]	9	hSpCas9	negative selection	3295552
57741775	57741798	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	0.07741712143090065	[144,144]	[0,0]	0	hSpCas9	positive selection	3375060
57744461	57744484	16	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	0.36250844813789157	[118,118]	[0,0]	2	hSpCas9	positive selection	3375061
57737237	57737260	16	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-1.7760967900916154	[523,523]	[0,0]	-9	hSpCas9	positive selection	3375062
57752797	57752820	16	+	26780180	HT29	viability (Avana library 4 designs)	GACGGCTGCTGCCTGTACAGCGG	KATNB1	ENSG00000140854	2.62730295594067	[]	[]	8	hSpCas9	negative selection	3433952
57751654	57751677	16	-	26780180	HT29	viability (Avana library 4 designs)	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	2.59659506045251	[]	[]	8	hSpCas9	negative selection	3433953
57752545	57752568	16	+	26780180	HT29	viability (Avana library 4 designs)	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	3.80924855277148	[]	[]	9	hSpCas9	negative selection	3433954
57741726	57741749	16	+	26780180	HT29	viability (Avana library 4 designs)	TGCTGGGCAAAGCCTCCGGGCGG	KATNB1	ENSG00000140854	1.72268492746585	[]	[]	6	hSpCas9	negative selection	3433955
57751654	57751677	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-3.35924730032307	[]	[]	-4	hSpCas9	negative selection	3520821
57752545	57752568	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-3.41505689427666	[]	[]	-4	hSpCas9	negative selection	3520822
57741726	57741749	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCTGGGCAAAGCCTCCGGGCGG	KATNB1	ENSG00000140854	-0.0233728120854237	[]	[]	0	hSpCas9	negative selection	3520823
57752797	57752820	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACGGCTGCTGCCTGTACAGCGG	KATNB1	ENSG00000140854	-6.06893784444638	[]	[]	-6	hSpCas9	negative selection	3520824
57741775	57741798	16	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-11.7412278648265	[]	[]	-8	hSpCas9	negative selection	3520825
57752779	57752802	16	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCGTCCTCTTCAACCCAGACGG	KATNB1	ENSG00000140854	1.01591999768685	[]	[]	1	hSpCas9	negative selection	3520826
57751654	57751677	16	-	26780180	A375	viability (Avana lentiGuide)	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	18.3453024009668	[]	[]	8	hSpCas9	negative selection	3629480
57752545	57752568	16	+	26780180	A375	viability (Avana lentiGuide)	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	23.6351806144877	[]	[]	9	hSpCas9	negative selection	3629481
57741726	57741749	16	+	26780180	A375	viability (Avana lentiGuide)	TGCTGGGCAAAGCCTCCGGGCGG	KATNB1	ENSG00000140854	14.5862771593039	[]	[]	8	hSpCas9	negative selection	3629482
57752797	57752820	16	+	26780180	A375	viability (Avana lentiGuide)	GACGGCTGCTGCCTGTACAGCGG	KATNB1	ENSG00000140854	22.0823994864577	[]	[]	9	hSpCas9	negative selection	3629483
57741775	57741798	16	-	26780180	A375	viability (Avana lentiGuide)	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	37.229575896121	[]	[]	9	hSpCas9	negative selection	3629484
57752779	57752802	16	+	26780180	A375	viability (Avana lentiGuide)	AGCGTCCTCTTCAACCCAGACGG	KATNB1	ENSG00000140854	19.616511202465	[]	[]	8	hSpCas9	negative selection	3629485
57751654	57751677	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.9005634790550852	[4]	[1,2]	-8	hSpCas9	positive selection	3738139
57752545	57752568	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-0.663415344061719	[4]	[2,1]	-7	hSpCas9	positive selection	3738140
57741726	57741749	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCTGGGCAAAGCCTCCGGGCGG	KATNB1	ENSG00000140854	0.10910865077010441	[4]	[4,4]	3	hSpCas9	positive selection	3738141
57752797	57752820	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACGGCTGCTGCCTGTACAGCGG	KATNB1	ENSG00000140854	0.08196323782171021	[4]	[5,4]	2	hSpCas9	positive selection	3738142
57741775	57741798	16	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.41616218898147295	[5]	[4,3]	-6	hSpCas9	positive selection	3738143
57752779	57752802	16	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCGTCCTCTTCAACCCAGACGG	KATNB1	ENSG00000140854	-0.015243739605262275	[5]	[5,4]	0	hSpCas9	positive selection	3738144
57751654	57751677	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-0.27392982133831767	[5]	[3,3]	-4	hSpCas9	positive selection	3846746
57752545	57752568	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-0.9714543065432897	[4]	[2,0]	-8	hSpCas9	positive selection	3846747
57741726	57741749	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCTGGGCAAAGCCTCCGGGCGG	KATNB1	ENSG00000140854	-0.6813755803970639	[5]	[3,0]	-7	hSpCas9	positive selection	3846748
57752797	57752820	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACGGCTGCTGCCTGTACAGCGG	KATNB1	ENSG00000140854	-0.7113545444401417	[4]	[2,1]	-7	hSpCas9	positive selection	3846749
57741775	57741798	16	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.0610721996366883	[6]	[2,1]	-8	hSpCas9	positive selection	3846750
57752779	57752802	16	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCGTCCTCTTCAACCCAGACGG	KATNB1	ENSG00000140854	-0.3714012948653809	[5]	[4,1]	-5	hSpCas9	positive selection	3846751
57737272	57737295	16	-	26780180	A375	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	1.00308401096915	[]	[]	4	hSpCas9	negative selection	3952757
57741768	57741791	16	+	26780180	A375	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	2.2661412625935	[]	[]	9	hSpCas9	negative selection	3952758
57744426	57744449	16	+	26780180	A375	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	2.38890736508091	[]	[]	9	hSpCas9	negative selection	3952759
57737237	57737260	16	+	26780180	A375	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	1.23491792809456	[]	[]	6	hSpCas9	negative selection	3952760
57744461	57744484	16	-	26780180	A375	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	1.29290624945153	[]	[]	7	hSpCas9	negative selection	3952761
57741775	57741798	16	-	26780180	A375	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	1.61522458491083	[]	[]	8	hSpCas9	negative selection	3952762
57737272	57737295	16	-	26780180	HT29	viability (GeCKOv2 library)	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.928160593531436	[]	[]	4	hSpCas9	negative selection	4060723
57741768	57741791	16	+	26780180	HT29	viability (GeCKOv2 library)	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.537372505466333	[]	[]	1	hSpCas9	negative selection	4060724
57744426	57744449	16	+	26780180	HT29	viability (GeCKOv2 library)	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	1.83337847413466	[]	[]	8	hSpCas9	negative selection	4060725
57737237	57737260	16	+	26780180	HT29	viability (GeCKOv2 library)	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.667975831031785	[]	[]	2	hSpCas9	negative selection	4060726
57744461	57744484	16	-	26780180	HT29	viability (GeCKOv2 library)	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	1.26138598666263	[]	[]	6	hSpCas9	negative selection	4060727
57741775	57741798	16	-	26780180	HT29	viability (GeCKOv2 library)	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	1.7299238059092	[]	[]	8	hSpCas9	negative selection	4060728
57737272	57737295	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.07338532134750686	[2]	[1,1]	1	hSpCas9	positive selection	4145923
57741768	57741791	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.18093120880774544	[3]	[2,1]	-4	hSpCas9	positive selection	4145924
57741804	57741827	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGGGCTCACCATGATGCAGTTGG	KATNB1	ENSG00000140854	0.06936702353674283	[3]	[2,2]	1	hSpCas9	positive selection	4145926
57737272	57737295	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.4693588326177212	[3]	[0,0,0,3]	3	hSpCas9	positive selection	4209945
57741768	57741791	16	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.8411456444903158	[4]	[1,0,0,0]	-9	hSpCas9	positive selection	4209946
57741804	57741827	16	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGGGCTCACCATGATGCAGTTGG	KATNB1	ENSG00000140854	-0.37486926492097855	[4]	[0,3,0,0]	-5	hSpCas9	positive selection	4209948
57741768	57741791	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.16475104370512952	[3]	[2,2]	-3	hSpCas9	positive selection	4277759
57737272	57737295	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	-0.15197174225993984	[2]	[2,1]	-3	hSpCas9	positive selection	4277760
57744426	57744449	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.6028883854694707	[3]	[1,0]	-8	hSpCas9	positive selection	4277761
57741775	57741798	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.25708607888131346	[2]	[2,0]	-5	hSpCas9	positive selection	4342015
57744461	57744484	16	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.43011179748208817	[2]	[1,0]	-7	hSpCas9	positive selection	4342016
57737237	57737260	16	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.45672952889172597	[3]	[3,4]	8	hSpCas9	positive selection	4342017
57750879	57750901	16	-	27760321	OCIAML3	viability	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-1.7251215492616758	[557,539]	[97,171]	-8	hSpCas9	negative selection	4411046
57751704	57751726	16	+	27760321	OCIAML3	viability	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	-1.7389747954285322	[716,551]	[91,219]	-8	hSpCas9	negative selection	4411047
57752830	57752852	16	+	27760321	OCIAML3	viability	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-1.5567723173966836	[775,660]	[126,272]	-8	hSpCas9	negative selection	4411048
57752868	57752890	16	+	27760321	OCIAML3	viability	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.3490633040956587	[433,374]	[192,318]	-4	hSpCas9	negative selection	4411049
57753111	57753133	16	-	27760321	OCIAML3	viability	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.6727038226892953	[647,549]	[324,250]	-6	hSpCas9	negative selection	4411050
57750879	57750901	16	-	27760321	OCIAML2	viability	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.746172446046998	[557,539]	[222,320]	-7	hSpCas9	negative selection	4494509
57751704	57751726	16	+	27760321	OCIAML2	viability	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	-0.46196100512076094	[716,551]	[343,403]	-5	hSpCas9	negative selection	4494510
57752830	57752852	16	+	27760321	OCIAML2	viability	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.5427311743188565	[775,660]	[379,420]	-6	hSpCas9	negative selection	4494511
57752868	57752890	16	+	27760321	OCIAML2	viability	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.3919671138117927	[433,374]	[208,300]	-4	hSpCas9	negative selection	4494512
57753111	57753133	16	-	27760321	OCIAML2	viability	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-1.5128436764116757	[647,549]	[157,183]	-8	hSpCas9	negative selection	4494513
57750879	57750901	16	-	27760321	MV411	viability	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.9643357079095076	[557,539]	[229,119]	-6	hSpCas9	negative selection	4577972
57751704	57751726	16	+	27760321	MV411	viability	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	-0.8949935532847588	[716,551]	[97,411]	-5	hSpCas9	negative selection	4577973
57752830	57752852	16	+	27760321	MV411	viability	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.6077769953528507	[775,660]	[443,108]	-4	hSpCas9	negative selection	4577974
57752868	57752890	16	+	27760321	MV411	viability	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	0.0804547701583179	[433,374]	[131,505]	0	hSpCas9	negative selection	4577975
57753111	57753133	16	-	27760321	MV411	viability	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-1.3329264525762867	[647,549]	[123,204]	-7	hSpCas9	negative selection	4577976
57750879	57750901	16	-	27760321	HL60	viability	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	0.4550801032059769	[557,539]	[697,528]	5	hSpCas9	negative selection	4661435
57751704	57751726	16	+	27760321	HL60	viability	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	0.5444305933259803	[716,551]	[744,755]	6	hSpCas9	negative selection	4661436
57752830	57752852	16	+	27760321	HL60	viability	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.32711828171701457	[775,660]	[393,542]	-4	hSpCas9	negative selection	4661437
57752868	57752890	16	+	27760321	HL60	viability	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	0.03711399784969158	[433,374]	[308,368]	0	hSpCas9	negative selection	4661438
57753111	57753133	16	-	27760321	HL60	viability	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.5554972314865014	[647,549]	[324,338]	-6	hSpCas9	negative selection	4661439
57750879	57750901	16	-	27760321	HT1080	viability	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.8951063689040721	[539,421]	[124,78]	-4	hSpCas9	negative selection	4744898
57751704	57751726	16	+	27760321	HT1080	viability	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	-1.0329740248385095	[551,430]	[46,148]	-4	hSpCas9	negative selection	4744899
57752830	57752852	16	+	27760321	HT1080	viability	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-2.2103677160466693	[660,515]	[53,46]	-6	hSpCas9	negative selection	4744900
57752868	57752890	16	+	27760321	HT1080	viability	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-2.085024052982879	[374,292]	[38,22]	-6	hSpCas9	negative selection	4744901
57753111	57753133	16	-	27760321	HT1080	viability	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-1.6702262010547955	[549,428]	[87,31]	-6	hSpCas9	negative selection	4744902
57750879	57750901	16	-	27760321	HT29	viability after 7 days	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.4826167709028036	[539,421]	[516,509,314]	-6	hSpCas9	negative selection	4828361
57751704	57751726	16	+	27760321	HT29	viability after 7 days	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	0.42559057893004737	[551,430]	[724,970,831]	6	hSpCas9	negative selection	4828362
57752830	57752852	16	+	27760321	HT29	viability after 7 days	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.29362062937045535	[660,515]	[458,1022,354]	-4	hSpCas9	negative selection	4828363
57752868	57752890	16	+	27760321	HT29	viability after 7 days	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.18114429949575545	[374,292]	[540,304,314]	-3	hSpCas9	negative selection	4828364
57753111	57753133	16	-	27760321	HT29	viability after 7 days	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.248857544036675	[549,428]	[557,626,410]	-4	hSpCas9	negative selection	4828365
57750879	57750901	16	-	27760321	HT29	viability after 25 days	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.8434186735781091	[539,421]	[155,492,275]	-6	hSpCas9	negative selection	4911824
57751704	57751726	16	+	27760321	HT29	viability after 25 days	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	-0.2511764286202879	[551,430]	[450,376,601]	-3	hSpCas9	negative selection	4911825
57752830	57752852	16	+	27760321	HT29	viability after 25 days	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-1.1558956785206917	[660,515]	[264,360,278]	-7	hSpCas9	negative selection	4911826
57752868	57752890	16	+	27760321	HT29	viability after 25 days	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.7969909767212454	[374,292]	[362,107,173]	-6	hSpCas9	negative selection	4911827
57753111	57753133	16	-	27760321	HT29	viability after 25 days	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-1.0278590828448726	[549,428]	[292,369,144]	-6	hSpCas9	negative selection	4911828
57750879	57750901	16	-	27760321	HT29	viability after 22 days	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.9475658715694457	[539,421]	[181,281,404]	-6	hSpCas9	negative selection	4995287
57751704	57751726	16	+	27760321	HT29	viability after 22 days	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	-0.2557916619855891	[551,430]	[409,380,639]	-3	hSpCas9	negative selection	4995288
57752830	57752852	16	+	27760321	HT29	viability after 22 days	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.6596198414255345	[660,515]	[692,365,223]	-5	hSpCas9	negative selection	4995289
57752868	57752890	16	+	27760321	HT29	viability after 22 days	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-1.0318216535653388	[374,292]	[204,186,173]	-6	hSpCas9	negative selection	4995290
57753111	57753133	16	-	27760321	HT29	viability after 22 days	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.28617231226015416	[549,428]	[644,512,226]	-3	hSpCas9	negative selection	4995291
57750879	57750901	16	-	27760321	HT29	viability after 19 days	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.05252980204295504	[539,421]	[198,628,720]	0	hSpCas9	negative selection	5078750
57751704	57751726	16	+	27760321	HT29	viability after 19 days	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	0.2968368821298848	[551,430]	[577,806,674]	3	hSpCas9	negative selection	5078751
57752830	57752852	16	+	27760321	HT29	viability after 19 days	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.8362995169325029	[660,515]	[319,462,342]	-6	hSpCas9	negative selection	5078752
57752868	57752890	16	+	27760321	HT29	viability after 19 days	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.6619230390372963	[374,292]	[310,139,278]	-5	hSpCas9	negative selection	5078753
57753111	57753133	16	-	27760321	HT29	viability after 19 days	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.22471504143193868	[549,428]	[547,387,506]	-2	hSpCas9	negative selection	5078754
57750879	57750901	16	-	27760321	HT29	viability after 16 days	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.8683007466281422	[539,421]	[259,298,321]	-6	hSpCas9	negative selection	5162213
57751704	57751726	16	+	27760321	HT29	viability after 16 days	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	0.02082526844968524	[551,430]	[451,657,550]	0	hSpCas9	negative selection	5162214
57752830	57752852	16	+	27760321	HT29	viability after 16 days	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.8023244456902733	[660,515]	[367,442,318]	-6	hSpCas9	negative selection	5162215
57752868	57752890	16	+	27760321	HT29	viability after 16 days	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.8147201773337394	[374,292]	[329,152,166]	-6	hSpCas9	negative selection	5162216
57753111	57753133	16	-	27760321	HT29	viability after 16 days	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.5094097146827858	[549,428]	[364,316,471]	-5	hSpCas9	negative selection	5162217
57750879	57750901	16	-	27760321	HT29	viability after 13 days	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.7353990588913043	[539,421]	[141,494,366]	-6	hSpCas9	negative selection	5245676
57751704	57751726	16	+	27760321	HT29	viability after 13 days	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	0.3419496364147291	[551,430]	[652,652,853]	4	hSpCas9	negative selection	5245677
57752830	57752852	16	+	27760321	HT29	viability after 13 days	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.5978870477860156	[660,515]	[373,606,376]	-6	hSpCas9	negative selection	5245678
57752868	57752890	16	+	27760321	HT29	viability after 13 days	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.41690787934059953	[374,292]	[270,347,253]	-5	hSpCas9	negative selection	5245679
57753111	57753133	16	-	27760321	HT29	viability after 13 days	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.23051243040359212	[549,428]	[624,383,444]	-3	hSpCas9	negative selection	5245680
57750879	57750901	16	-	27760321	HT29	viability after 10 days	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.349859218173595	[539,421]	[479,592,346]	-4	hSpCas9	negative selection	5329139
57751704	57751726	16	+	27760321	HT29	viability after 10 days	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	0.5185498416588292	[551,430]	[852,766,1010]	7	hSpCas9	negative selection	5329140
57752830	57752852	16	+	27760321	HT29	viability after 10 days	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.6976419476938537	[660,515]	[373,606,383]	-7	hSpCas9	negative selection	5329141
57752868	57752890	16	+	27760321	HT29	viability after 10 days	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	-0.3549697943931731	[374,292]	[323,262,387]	-4	hSpCas9	negative selection	5329142
57753111	57753133	16	-	27760321	HT29	viability after 10 days	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.0012055689396910374	[549,428]	[591,662,578]	0	hSpCas9	negative selection	5329143
57750879	57750901	16	-	27760321	MOLM13	viability	GGCTACAAACTCGCCGTACGGG	KATNB1	ENSG00000140854	-0.43665844299496287	[557,539]	[110,329]	-3	hSpCas9	negative selection	5412602
57751704	57751726	16	+	27760321	MOLM13	viability	GCAGATGACCACACCGTGAAGG	KATNB1	ENSG00000140854	0.5211704218221378	[716,551]	[745,308]	3	hSpCas9	negative selection	5412603
57752830	57752852	16	+	27760321	MOLM13	viability	TCACTGCGTGTCTACGGCTGGG	KATNB1	ENSG00000140854	-0.0033518064270127157	[775,660]	[320,472]	0	hSpCas9	negative selection	5412604
57752868	57752890	16	+	27760321	MOLM13	viability	TGATGTGGTCCTCGTCAACTGG	KATNB1	ENSG00000140854	0.10299071997562714	[433,374]	[103,363]	0	hSpCas9	negative selection	5412605
57753111	57753133	16	-	27760321	MOLM13	viability	CGCGTCAGATCCACCACGTAGG	KATNB1	ENSG00000140854	-0.9932457502532923	[647,549]	[280,73]	-5	hSpCas9	negative selection	5412606
57735756	57735779	16	+	27661255	K562	viability	GAGGGTCGGTTGTCAAGCAGCGG	KATNB1	ENSG00000140854	0.18523361756923407	[1287,1262]	[1268,1064]	6	dCas9-KRAB	negative selection	5487751
57735772	57735795	16	+	27661255	K562	viability	GCAGCGGCCAATCAAGGCAGGGG	KATNB1	ENSG00000140854	0.24639769922888088	[348,322]	[354,287]	8	dCas9-KRAB	negative selection	5487752
57735787	57735810	16	+	27661255	K562	viability	GGCAGGGGATGGAGGCAAGTGGG	KATNB1	ENSG00000140854	0.18519115820125798	[1296,1558]	[1263,1316]	6	dCas9-KRAB	negative selection	5487753
57735843	57735866	16	+	27661255	K562	viability	GCCGCAGCTGCAGGTGGAGTGGG	KATNB1	ENSG00000140854	0.17050663886818923	[668,549]	[652,461]	6	dCas9-KRAB	negative selection	5487754
57736157	57736180	16	+	27661255	K562	viability	GGGAGACCCCGCGAGCATATGGG	KATNB1	ENSG00000140854	0.1863215009349661	[561,656]	[620,493]	6	dCas9-KRAB	negative selection	5487755
57736210	57736233	16	+	27661255	K562	viability	GGGGCCACGTGAGGGATATCGGG	KATNB1	ENSG00000140854	0.1754563310874112	[1003,1148]	[1005,936]	6	dCas9-KRAB	negative selection	5487756
57736282	57736305	16	+	27661255	K562	viability	GTGTGAACGGAGGACTAGAGAGG	KATNB1	ENSG00000140854	0.2090535792777125	[952,1182]	[1065,910]	7	dCas9-KRAB	negative selection	5487757
57741768	57741791	16	+	27260156	BXPC3	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.09709688237669756	[874]	[868,887,933,1268]	2	hSpCas9	negative selection	5550219
57737272	57737295	16	-	27260156	BXPC3	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.49725041262950614	[434]	[437,588,801,779]	9	hSpCas9	negative selection	5550220
57744426	57744449	16	+	27260156	BXPC3	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.1655434411303216	[574]	[615,654,808,614]	3	hSpCas9	negative selection	5550221
57741775	57741798	16	-	27260156	BXPC3	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.5755555210385916	[313]	[159,218,259,251]	-8	hSpCas9	negative selection	5614475
57744461	57744484	16	-	27260156	BXPC3	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.5736272667107092	[269]	[169,226,169,189]	-8	hSpCas9	negative selection	5614476
57737237	57737260	16	+	27260156	BXPC3	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.000155729698219087	[959]	[907,972,1022,1132]	0	hSpCas9	negative selection	5614477
57741768	57741791	16	+	27260156	A673	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.34754238929247205	[874]	[889,841,734,842]	-7	hSpCas9	negative selection	5671470
57737272	57737295	16	-	27260156	A673	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.44889567894635823	[434]	[953,668,601,651]	8	hSpCas9	negative selection	5671471
57744426	57744449	16	+	27260156	A673	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.11087840156903955	[574]	[722,574,593,677]	-3	hSpCas9	negative selection	5671472
57741775	57741798	16	-	27260156	A673	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.146798911561975	[313]	[235,185,148,113]	-9	hSpCas9	negative selection	5735726
57744461	57744484	16	-	27260156	A673	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.5542899685598637	[269]	[226,215,270,165]	-8	hSpCas9	negative selection	5735727
57737237	57737260	16	+	27260156	A673	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.18724208313216018	[959]	[1040,1001,999,1007]	-5	hSpCas9	negative selection	5735728
57741768	57741791	16	+	27260156	A375	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-1.5069378036758925	[874]	[269,467,303,403]	-9	hSpCas9	negative selection	5792721
57737272	57737295	16	-	27260156	A375	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.4171497641212706	[434]	[561,873,683,623]	6	hSpCas9	negative selection	5792722
57744426	57744449	16	+	27260156	A375	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.9289908344251695	[574]	[180,455,555,242]	-8	hSpCas9	negative selection	5792723
57741775	57741798	16	-	27260156	A375	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.5099630066387477	[313]	[92,66,126,208]	-9	hSpCas9	negative selection	5856977
57744461	57744484	16	-	27260156	A375	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.4504577364852527	[269]	[78,227,30,135]	-9	hSpCas9	negative selection	5856978
57737237	57737260	16	+	27260156	A375	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.2517803346940227	[959]	[1016,1093,797,882]	-4	hSpCas9	negative selection	5856979
57741768	57741791	16	+	27260156	COLO741	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.15804284658701429	[874]	[1208,1219,1302]	3	hSpCas9	negative selection	5913972
57737272	57737295	16	-	27260156	COLO741	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.5268880807469425	[434]	[956,870,600]	9	hSpCas9	negative selection	5913973
57744426	57744449	16	+	27260156	COLO741	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.3446684122166922	[574]	[1143,873,805]	7	hSpCas9	negative selection	5913974
57741775	57741798	16	-	27260156	COLO741	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.6858045245768771	[313]	[263,278,208]	-8	hSpCas9	negative selection	5978228
57744461	57744484	16	-	27260156	COLO741	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.8148961855491048	[269]	[306,162,131]	-9	hSpCas9	negative selection	5978229
57737237	57737260	16	+	27260156	COLO741	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.18653524048243963	[959]	[1807,1144,1274]	4	hSpCas9	negative selection	5978230
57741768	57741791	16	+	27260156	CAL120	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.9162609700257659	[874]	[530,631,560]	-8	hSpCas9	negative selection	6035223
57737272	57737295	16	-	27260156	CAL120	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.8533386753656266	[434]	[1079,954,914]	9	hSpCas9	negative selection	6035224
57744426	57744449	16	+	27260156	CAL120	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-1.2003705077070839	[574]	[291,379,259]	-9	hSpCas9	negative selection	6035225
57741775	57741798	16	-	27260156	CAL120	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-2.213026881932969	[313]	[89,42,119]	-9	hSpCas9	negative selection	6099479
57744461	57744484	16	-	27260156	CAL120	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.8787175636236724	[269]	[133,84,61]	-9	hSpCas9	negative selection	6099480
57737237	57737260	16	+	27260156	CAL120	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.5233583459845556	[959]	[812,880,796]	-6	hSpCas9	negative selection	6099481
57741768	57741791	16	+	27260156	CADOES1	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.020268798585932446	[874]	[1085,642,543,940]	0	hSpCas9	negative selection	6156474
57737272	57737295	16	-	27260156	CADOES1	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.7645889295817415	[434]	[560,780,562,850]	9	hSpCas9	negative selection	6156475
57744426	57744449	16	+	27260156	CADOES1	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.015518332665840295	[574]	[481,579,511,542]	0	hSpCas9	negative selection	6156476
57741775	57741798	16	-	27260156	CADOES1	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.8112500242612251	[313]	[207,132,120,204]	-8	hSpCas9	negative selection	6220730
57744461	57744484	16	-	27260156	CADOES1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.792180868411541	[269]	[112,157,167,140]	-8	hSpCas9	negative selection	6220731
57737237	57737260	16	+	27260156	CADOES1	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.20441956056152	[959]	[1010,1134,745,1230]	3	hSpCas9	negative selection	6220732
57741768	57741791	16	+	27260156	EWS502	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.23628338982555086	[874]	[569,892,834,874]	-4	hSpCas9	negative selection	6277725
57737272	57737295	16	-	27260156	EWS502	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6241210975113523	[434]	[724,686,665,761]	9	hSpCas9	negative selection	6277726
57744426	57744449	16	+	27260156	EWS502	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.1632683156986739	[574]	[537,549,505,581]	-3	hSpCas9	negative selection	6277727
57741775	57741798	16	-	27260156	EWS502	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.7945221409974685	[313]	[170,169,257,169]	-8	hSpCas9	negative selection	6341981
57744461	57744484	16	-	27260156	EWS502	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.3272337066635875	[269]	[92,123,154,83]	-9	hSpCas9	negative selection	6341982
57737237	57737260	16	+	27260156	EWS502	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.20996607218318308	[959]	[1220,1051,1114,1320]	3	hSpCas9	negative selection	6341983
57741768	57741791	16	+	27260156	EW8	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.6355639678813705	[874]	[515,379,393,550]	-8	hSpCas9	negative selection	6398976
57737272	57737295	16	-	27260156	EW8	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.4881845318520951	[434]	[714,496,334,480]	8	hSpCas9	negative selection	6398977
57744426	57744449	16	+	27260156	EW8	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.46064473732464944	[574]	[304,409,303,336]	-7	hSpCas9	negative selection	6398978
57741775	57741798	16	-	27260156	EW8	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.5011151187693392	[313]	[89,111,56,105]	-9	hSpCas9	negative selection	6463232
57744461	57744484	16	-	27260156	EW8	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.500199371058862	[269]	[90,62,86,67]	-9	hSpCas9	negative selection	6463233
57737237	57737260	16	+	27260156	EW8	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.07553334193773664	[959]	[801,715,672,777]	-1	hSpCas9	negative selection	6463234
57741768	57741791	16	+	27260156	CORL105	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.18648784165078247	[874]	[1172,1132,1170,1186]	3	hSpCas9	negative selection	6520227
57737272	57737295	16	-	27260156	CORL105	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.7362783453940057	[434]	[892,780,886,840]	9	hSpCas9	negative selection	6520228
57744426	57744449	16	+	27260156	CORL105	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.2207355387732044	[574]	[724,758,930,743]	4	hSpCas9	negative selection	6520229
57741775	57741798	16	-	27260156	CORL105	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.33412466138908603	[313]	[283,194,300,388]	-6	hSpCas9	negative selection	6584483
57744461	57744484	16	-	27260156	CORL105	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.11397197073456766	[269]	[260,316,331,262]	-2	hSpCas9	negative selection	6584484
57737237	57737260	16	+	27260156	CORL105	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.08618878983492673	[959]	[1380,1042,1334,1044]	1	hSpCas9	negative selection	6584485
57741768	57741791	16	+	27260156	HS294T	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.2441560462589354	[874]	[297,197,263,402]	-3	hSpCas9	negative selection	6641478
57737272	57737295	16	-	27260156	HS294T	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6742902778312957	[434]	[312,276,249,219]	8	hSpCas9	negative selection	6641479
57744426	57744449	16	+	27260156	HS294T	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.35712428864944035	[574]	[108,141,226,232]	-5	hSpCas9	negative selection	6641480
57741775	57741798	16	-	27260156	HS294T	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.620407193737881	[313]	[34,29,36,59]	-9	hSpCas9	negative selection	6705734
57744461	57744484	16	-	27260156	HS294T	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.8496401586589104	[269]	[21,39,78,101]	-8	hSpCas9	negative selection	6705735
57737237	57737260	16	+	27260156	HS294T	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.6077332733361023	[959]	[220,183,237,352]	-7	hSpCas9	negative selection	6705736
57741768	57741791	16	+	27260156	HCC44	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.2980203804769215	[874]	[994,605,903,771]	-5	hSpCas9	negative selection	6762729
57737272	57737295	16	-	27260156	HCC44	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.7543550107888942	[434]	[858,414,1148,1000]	9	hSpCas9	negative selection	6762730
57744426	57744449	16	+	27260156	HCC44	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.14361437573251623	[574]	[803,445,1139,600]	2	hSpCas9	negative selection	6762731
57741775	57741798	16	-	27260156	HCC44	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.5529722202522451	[313]	[490,143,162,192]	-7	hSpCas9	negative selection	6826985
57744461	57744484	16	-	27260156	HCC44	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.8248288091540381	[269]	[189,168,183,149]	-8	hSpCas9	negative selection	6826986
57737237	57737260	16	+	27260156	HCC44	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.42939126443087927	[959]	[1372,1420,1805,1298]	7	hSpCas9	negative selection	6826987
57741768	57741791	16	+	27260156	G402	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.23221979844206486	[874]	[1101,725,1050,776]	-3	hSpCas9	negative selection	6883980
57737272	57737295	16	-	27260156	G402	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.338916381477919	[434]	[815,395,620,845]	4	hSpCas9	negative selection	6883981
57744426	57744449	16	+	27260156	G402	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.4433870106673026	[574]	[425,592,552,482]	-5	hSpCas9	negative selection	6883982
57741775	57741798	16	-	27260156	G402	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.3036682313838679	[313]	[358,600,197,115]	-4	hSpCas9	negative selection	6948236
57744461	57744484	16	-	27260156	G402	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.5970490467249787	[269]	[94,266,349,146]	-6	hSpCas9	negative selection	6948237
57737237	57737260	16	+	27260156	G402	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.09795032776455392	[959]	[905,1458,1297,1305]	1	hSpCas9	negative selection	6948238
57741768	57741791	16	+	27260156	L33	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.20338130810635713	[874]	[993,426,611,1019]	4	hSpCas9	negative selection	7005231
57737272	57737295	16	-	27260156	L33	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6338568869869484	[434]	[841,241,348,706]	9	hSpCas9	negative selection	7005232
57744426	57744449	16	+	27260156	L33	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.5166418124139194	[574]	[674,343,547,906]	9	hSpCas9	negative selection	7005233
57741775	57741798	16	-	27260156	L33	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.4632973681195534	[313]	[119,39,43,166]	-9	hSpCas9	negative selection	7069487
57744461	57744484	16	-	27260156	L33	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.29633818628565045	[269]	[243,60,100,323]	-6	hSpCas9	negative selection	7069488
57737237	57737260	16	+	27260156	L33	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.0749853872732027	[959]	[1025,403,685,941]	1	hSpCas9	negative selection	7069489
57741768	57741791	16	+	27260156	K562	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.36903160987947103	[874]	[1122,1178,851,885]	4	hSpCas9	negative selection	7126482
57737272	57737295	16	-	27260156	K562	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.636746528033027	[434]	[414,580,784,600]	7	hSpCas9	negative selection	7126483
57744426	57744449	16	+	27260156	K562	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.36143644259321894	[574]	[700,495,594,804]	4	hSpCas9	negative selection	7126484
57741775	57741798	16	-	27260156	K562	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.3723033117685297	[313]	[87,302,206,251]	-4	hSpCas9	negative selection	7190738
57744461	57744484	16	-	27260156	K562	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.22176402766682446	[269]	[113,133,386,177]	-3	hSpCas9	negative selection	7190739
57737237	57737260	16	+	27260156	K562	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.4785419493793688	[959]	[1077,1202,2106,435]	6	hSpCas9	negative selection	7190740
57741768	57741791	16	+	27260156	HT29	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.03324887082105199	[874]	[965,1074,1178,939]	0	hSpCas9	negative selection	7247733
57737272	57737295	16	-	27260156	HT29	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6797134494823938	[434]	[937,1121,796,587]	9	hSpCas9	negative selection	7247734
57744426	57744449	16	+	27260156	HT29	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.2296663130545019	[574]	[693,631,1148,776]	4	hSpCas9	negative selection	7247735
57741775	57741798	16	-	27260156	HT29	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.05486298380707999	[313]	[396,333,407,331]	-1	hSpCas9	negative selection	7311989
57744461	57744484	16	-	27260156	HT29	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.6486829934864917	[269]	[195,208,203,223]	-8	hSpCas9	negative selection	7311990
57737237	57737260	16	+	27260156	HT29	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.011602206026402717	[959]	[1250,1265,1290,932]	0	hSpCas9	negative selection	7311991
57741768	57741791	16	+	27260156	MHHES1	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.16887069760352458	[874]	[1375,1047,1042,991]	3	hSpCas9	negative selection	7368984
57737272	57737295	16	-	27260156	MHHES1	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.40311419778401963	[434]	[673,615,758,550]	7	hSpCas9	negative selection	7368985
57744426	57744449	16	+	27260156	MHHES1	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.1365674236603241	[574]	[778,540,864,651]	2	hSpCas9	negative selection	7368986
57741775	57741798	16	-	27260156	MHHES1	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.6613499740818574	[313]	[256,172,258,203]	-8	hSpCas9	negative selection	7433240
57744461	57744484	16	-	27260156	MHHES1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.18120634262037472	[269]	[350,142,336,239]	-3	hSpCas9	negative selection	7433241
57737237	57737260	16	+	27260156	MHHES1	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.0681018878294346	[959]	[1043,1447,859,837]	-1	hSpCas9	negative selection	7433242
57741768	57741791	16	+	27260156	MEWO	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.279405562963019	[874]	[1154,933,922]	6	hSpCas9	negative selection	7490235
57737272	57737295	16	-	27260156	MEWO	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6928835499221706	[434]	[669,619,685]	9	hSpCas9	negative selection	7490236
57744426	57744449	16	+	27260156	MEWO	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.5320317879279602	[574]	[1077,682,630]	9	hSpCas9	negative selection	7490237
57741775	57741798	16	-	27260156	MEWO	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.35289898730696223	[313]	[275,213,208]	-6	hSpCas9	negative selection	7554491
57744461	57744484	16	-	27260156	MEWO	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.40305875133619185	[269]	[236,181,162]	-7	hSpCas9	negative selection	7554492
57737237	57737260	16	+	27260156	MEWO	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.40844893650408043	[959]	[1398,989,1227]	8	hSpCas9	negative selection	7554493
57741768	57741791	16	+	27260156	LNCAPCLONEFGC	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.8506967280284116	[874]	[256,562,498,442]	-8	hSpCas9	negative selection	7611486
57737272	57737295	16	-	27260156	LNCAPCLONEFGC	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.7217240263024275	[434]	[599,448,870,725]	9	hSpCas9	negative selection	7611487
57744426	57744449	16	+	27260156	LNCAPCLONEFGC	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-1.2805169529408933	[574]	[219,200,198,235]	-9	hSpCas9	negative selection	7611488
57741775	57741798	16	-	27260156	LNCAPCLONEFGC	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.6558931057516104	[313]	[75,104,94,84]	-9	hSpCas9	negative selection	7675742
57744461	57744484	16	-	27260156	LNCAPCLONEFGC	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.6469330256396015	[269]	[56,95,80,77]	-9	hSpCas9	negative selection	7675743
57737237	57737260	16	+	27260156	LNCAPCLONEFGC	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.21426952793678844	[959]	[938,682,785,595]	-3	hSpCas9	negative selection	7675744
57741768	57741791	16	+	27260156	PANC0327	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.5429038468508927	[874]	[488,660,603,359]	-6	hSpCas9	negative selection	7732737
57737272	57737295	16	-	27260156	PANC0327	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.5720919691463209	[434]	[594,530,576,601]	8	hSpCas9	negative selection	7732738
57744426	57744449	16	+	27260156	PANC0327	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-1.108425206394221	[574]	[271,302,262,103]	-8	hSpCas9	negative selection	7732739
57741775	57741798	16	-	27260156	PANC0327	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.2004831889344523	[313]	[197,86,42,167]	-9	hSpCas9	negative selection	7796993
57744461	57744484	16	-	27260156	PANC0327	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-2.5456831174338292	[269]	[44,14,54,52]	-9	hSpCas9	negative selection	7796994
57737237	57737260	16	+	27260156	PANC0327	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.4563108598650111	[959]	[505,453,1067,470]	-6	hSpCas9	negative selection	7796995
57741768	57741791	16	+	27260156	NCIH2009	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.49759202258403706	[874]	[788,810,981]	-6	hSpCas9	negative selection	7853988
57737272	57737295	16	-	27260156	NCIH2009	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.9410676085778042	[434]	[1253,993,1270]	9	hSpCas9	negative selection	7853989
57744426	57744449	16	+	27260156	NCIH2009	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.31916884918689775	[574]	[812,593,557]	-4	hSpCas9	negative selection	7853990
57741775	57741798	16	-	27260156	NCIH2009	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.4273986689659712	[313]	[194,182,116]	-9	hSpCas9	negative selection	7918244
57744461	57744484	16	-	27260156	NCIH2009	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.8046067611609169	[269]	[350,118,205]	-7	hSpCas9	negative selection	7918245
57737237	57737260	16	+	27260156	NCIH2009	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.36135539155219776	[959]	[910,1384,801]	-5	hSpCas9	negative selection	7918246
57741768	57741791	16	+	27260156	NCIH1373	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.5813658202623129	[874]	[893,338,578,234]	-5	hSpCas9	negative selection	7975239
57737272	57737295	16	-	27260156	NCIH1373	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.7857589465415493	[434]	[1280,647,939,146]	7	hSpCas9	negative selection	7975240
57744426	57744449	16	+	27260156	NCIH1373	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.3607640035396965	[574]	[372,353,695,151]	-4	hSpCas9	negative selection	7975241
57741775	57741798	16	-	27260156	NCIH1373	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.5084748932096796	[313]	[49,261,66,22]	-9	hSpCas9	negative selection	8039495
57744461	57744484	16	-	27260156	NCIH1373	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.6147150254977225	[269]	[153,87,207,92]	-6	hSpCas9	negative selection	8039496
57737237	57737260	16	+	27260156	NCIH1373	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.07927523556747718	[959]	[926,912,571,447]	-1	hSpCas9	negative selection	8039497
57741768	57741791	16	+	27260156	PATU8902	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-1.6572950959150734	[874]	[379,403,391,361]	-8	hSpCas9	negative selection	8096490
57737272	57737295	16	-	27260156	PATU8902	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6065084962670925	[434]	[627,793,633,1810]	6	hSpCas9	negative selection	8096491
57744426	57744449	16	+	27260156	PATU8902	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-1.2754613756390618	[574]	[404,491,169,289]	-8	hSpCas9	negative selection	8096492
57741775	57741798	16	-	27260156	PATU8902	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.880842889407642	[313]	[123,79,153,104]	-9	hSpCas9	negative selection	8160746
57744461	57744484	16	-	27260156	PATU8902	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-2.2592212872932276	[269]	[110,48,23,151]	-9	hSpCas9	negative selection	8160747
57737237	57737260	16	+	27260156	PATU8902	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.11737390813278714	[959]	[1161,1085,1150,1584]	-1	hSpCas9	negative selection	8160748
57741768	57741791	16	+	27260156	PANC1	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.14261681154190553	[874]	[848,1073,953,528]	2	hSpCas9	negative selection	8217741
57737272	57737295	16	-	27260156	PANC1	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.7284309584483231	[434]	[576,685,695,535]	9	hSpCas9	negative selection	8217742
57744426	57744449	16	+	27260156	PANC1	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.49365274490288963	[574]	[340,293,379,367]	-6	hSpCas9	negative selection	8217743
57741775	57741798	16	-	27260156	PANC1	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.9012120195099653	[313]	[136,125,251,69]	-8	hSpCas9	negative selection	8281997
57744461	57744484	16	-	27260156	PANC1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.6676038588580102	[269]	[128,132,194,125]	-7	hSpCas9	negative selection	8281998
57737237	57737260	16	+	27260156	PANC1	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.017588184063409118	[959]	[719,1097,818,688]	0	hSpCas9	negative selection	8281999
57741768	57741791	16	+	27260156	PANC0813	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.7972777060349397	[874]	[705,509,579,579]	-8	hSpCas9	negative selection	8338992
57737272	57737295	16	-	27260156	PANC0813	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.7034577596788245	[434]	[848,861,678,931]	9	hSpCas9	negative selection	8338993
57744426	57744449	16	+	27260156	PANC0813	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.45043789883194085	[574]	[643,478,430,438]	-6	hSpCas9	negative selection	8338994
57741775	57741798	16	-	27260156	PANC0813	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-2.187604076102926	[313]	[100,109,61,53]	-9	hSpCas9	negative selection	8403248
57744461	57744484	16	-	27260156	PANC0813	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.7917989844340323	[269]	[108,186,127,294]	-8	hSpCas9	negative selection	8403249
57737237	57737260	16	+	27260156	PANC0813	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.3187980568846165	[959]	[854,954,960,842]	-5	hSpCas9	negative selection	8403250
57741768	57741791	16	+	27260156	RDES	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.14627047047299468	[874]	[921,1032,1286,1255]	2	hSpCas9	negative selection	8460243
57737272	57737295	16	-	27260156	RDES	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.8675353146827771	[434]	[671,815,1139,1094]	9	hSpCas9	negative selection	8460244
57744426	57744449	16	+	27260156	RDES	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.03372477873593338	[574]	[539,576,766,876]	0	hSpCas9	negative selection	8460245
57741775	57741798	16	-	27260156	RDES	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.4872917747053116	[313]	[290,131,296,316]	-7	hSpCas9	negative selection	8524499
57744461	57744484	16	-	27260156	RDES	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.4498855298893447	[269]	[162,273,208,271]	-6	hSpCas9	negative selection	8524500
57737237	57737260	16	+	27260156	RDES	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.09582741737294076	[959]	[873,1104,1500,1310]	1	hSpCas9	negative selection	8524501
57741768	57741791	16	+	27260156	PC3	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.3442314105441717	[874]	[754,1281,1841,850]	7	hSpCas9	negative selection	8581494
57737272	57737295	16	-	27260156	PC3	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.5798080108039787	[434]	[408,788,1015,548]	9	hSpCas9	negative selection	8581495
57744426	57744449	16	+	27260156	PC3	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.1940343581908301	[574]	[466,541,1236,619]	4	hSpCas9	negative selection	8581496
57741775	57741798	16	-	27260156	PC3	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.5356124697386164	[313]	[106,388,205,174]	-8	hSpCas9	negative selection	8645750
57744461	57744484	16	-	27260156	PC3	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.1392792305805558	[269]	[89,219,334,429]	-3	hSpCas9	negative selection	8645751
57737237	57737260	16	+	27260156	PC3	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.07818322740437145	[959]	[609,1099,1262,1249]	1	hSpCas9	negative selection	8645752
57741768	57741791	16	+	27260156	PATU8988T	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.8645310081320491	[874]	[307,599,444,521]	-8	hSpCas9	negative selection	8702745
57737272	57737295	16	-	27260156	PATU8988T	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.5043877461146102	[434]	[578,701,595,510]	8	hSpCas9	negative selection	8702746
57744426	57744449	16	+	27260156	PATU8988T	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.015730778435766313	[574]	[668,550,436,592]	0	hSpCas9	negative selection	8702747
57741775	57741798	16	-	27260156	PATU8988T	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.0826516034522937	[313]	[58,141,302,59]	-9	hSpCas9	negative selection	8767001
57744461	57744484	16	-	27260156	PATU8988T	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.8326733349399602	[269]	[105,86,298,80]	-8	hSpCas9	negative selection	8767002
57737237	57737260	16	+	27260156	PATU8988T	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.46786062628708025	[959]	[427,800,834,624]	-6	hSpCas9	negative selection	8767003
57741768	57741791	16	+	27260156	T47D	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.03357614094450978	[874]	[1107,881,963,1240]	0	hSpCas9	negative selection	8823996
57737272	57737295	16	-	27260156	T47D	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.5513658383387016	[434]	[820,684,685,785]	9	hSpCas9	negative selection	8823997
57744426	57744449	16	+	27260156	T47D	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.10427862808387128	[574]	[705,657,721,801]	2	hSpCas9	negative selection	8823998
57741775	57741798	16	-	27260156	T47D	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.4291839196343248	[313]	[249,195,302,345]	-7	hSpCas9	negative selection	8888252
57744461	57744484	16	-	27260156	T47D	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.36805872405213536	[269]	[257,223,259,233]	-7	hSpCas9	negative selection	8888253
57737237	57737260	16	+	27260156	T47D	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.09428073879178611	[959]	[1048,1017,1103,1019]	-2	hSpCas9	negative selection	8888254
57741768	57741791	16	+	27260156	SU8686	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.4376098289141971	[874]	[711,771,457,573]	-6	hSpCas9	negative selection	8945247
57737272	57737295	16	-	27260156	SU8686	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6080208254469679	[434]	[608,568,677,810]	8	hSpCas9	negative selection	8945248
57744426	57744449	16	+	27260156	SU8686	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.24914101162326463	[574]	[560,538,327,462]	-4	hSpCas9	negative selection	8945249
57741775	57741798	16	-	27260156	SU8686	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-1.157426529579726	[313]	[159,130,140,120]	-9	hSpCas9	negative selection	9009503
57744461	57744484	16	-	27260156	SU8686	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.40431905049576433	[269]	[145,247,194,221]	-6	hSpCas9	negative selection	9009504
57737237	57737260	16	+	27260156	SU8686	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	-0.2076945599053278	[959]	[929,645,951,767]	-4	hSpCas9	negative selection	9009505
57741768	57741791	16	+	27260156	SKES1	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.29552872638437533	[874]	[979,1075,1094,1105]	6	hSpCas9	negative selection	9066498
57737272	57737295	16	-	27260156	SKES1	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.6743617988210628	[434]	[784,771,702,542]	9	hSpCas9	negative selection	9066499
57744426	57744449	16	+	27260156	SKES1	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.4398069495328156	[574]	[732,745,992,635]	8	hSpCas9	negative selection	9066500
57741775	57741798	16	-	27260156	SKES1	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.3547412321225504	[313]	[285,247,279,176]	-7	hSpCas9	negative selection	9130754
57744461	57744484	16	-	27260156	SKES1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.5488567386044667	[269]	[316,174,136,129]	-8	hSpCas9	negative selection	9130755
57737237	57737260	16	+	27260156	SKES1	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.1416193276823885	[959]	[1343,1189,795,955]	3	hSpCas9	negative selection	9130756
57741768	57741791	16	+	27260156	TOV112D	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	-0.03336513018155707	[874]	[726,1457,662,716]	0	hSpCas9	negative selection	9187749
57737272	57737295	16	-	27260156	TOV112D	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.44275261564668	[434]	[697,717,523,470]	7	hSpCas9	negative selection	9187750
57744426	57744449	16	+	27260156	TOV112D	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.23398947198566122	[574]	[597,715,577,814]	4	hSpCas9	negative selection	9187751
57741775	57741798	16	-	27260156	TOV112D	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.7543503736733868	[313]	[177,277,115,194]	-9	hSpCas9	negative selection	9252005
57744461	57744484	16	-	27260156	TOV112D	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.7033285086755556	[269]	[122,140,142,244]	-8	hSpCas9	negative selection	9252006
57737237	57737260	16	+	27260156	TOV112D	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.3070317289668707	[959]	[1279,1279,1109,1117]	6	hSpCas9	negative selection	9252007
57741768	57741791	16	+	27260156	TC71	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.4171041481928319	[874]	[1083,1041,1314,1590]	8	hSpCas9	negative selection	9309000
57737272	57737295	16	-	27260156	TC71	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.4413780205028647	[434]	[618,553,703,654]	8	hSpCas9	negative selection	9309001
57744426	57744449	16	+	27260156	TC71	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	0.39609394439872003	[574]	[814,801,617,1028]	8	hSpCas9	negative selection	9309002
57741775	57741798	16	-	27260156	TC71	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.15390763283061004	[313]	[387,281,220,320]	-4	hSpCas9	negative selection	9373256
57744461	57744484	16	-	27260156	TC71	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.19255875851843518	[269]	[254,213,197,353]	-5	hSpCas9	negative selection	9373257
57737237	57737260	16	+	27260156	TC71	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.2760819170178621	[959]	[1138,1309,1162,1385]	6	hSpCas9	negative selection	9373258
57741768	57741791	16	+	27260156	TC32	viability	ATGACTGCCGCGTCAACCTGTGG	KATNB1	ENSG00000140854	0.04321605047253718	[874]	[717,511,1371,982]	0	hSpCas9	negative selection	9430251
57737272	57737295	16	-	27260156	TC32	viability	AAACCACTCACGCAACTTCCAGG	KATNB1	ENSG00000140854	0.532381767304939	[434]	[555,390,767,734]	8	hSpCas9	negative selection	9430252
57744426	57744449	16	+	27260156	TC32	viability	CGTCCGCCTCAACACCCCCGAGG	KATNB1	ENSG00000140854	-0.048609561395566936	[574]	[479,491,503,597]	-1	hSpCas9	negative selection	9430253
57741775	57741798	16	-	27260156	TC32	viability	TGATGGACCACAGGTTGACGCGG	KATNB1	ENSG00000140854	-0.831056550494554	[313]	[186,45,207,269]	-9	hSpCas9	negative selection	9494507
57744461	57744484	16	-	27260156	TC32	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.3967237437284552	[269]	[132,227,196,194]	-6	hSpCas9	negative selection	9494508
57737237	57737260	16	+	27260156	TC32	viability	CTGAAGGATGGCCACCCCTGTGG	KATNB1	ENSG00000140854	0.3544150648501807	[959]	[951,1094,1329,1246]	6	hSpCas9	negative selection	9494509
57737252	57737275	16	-	27869803	HPAFII	viability after 27 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	0.016585460434448307	[139]	[80,68,NaN]	0	hSpCas9	negative selection	9557614
57741784	57741807	16	-	27869803	HPAFII	viability after 27 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	0.32687214888641436	[66]	[95,0,NaN]	2	hSpCas9	negative selection	9557615
57744415	57744438	16	-	27869803	HPAFII	viability after 27 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.6175810382874778	[129]	[55,34,NaN]	-4	hSpCas9	negative selection	9557616
57750876	57750899	16	-	27869803	HPAFII	viability after 27 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.9837478409510907	[369]	[81,111,NaN]	-6	hSpCas9	negative selection	9557617
57751654	57751677	16	-	27869803	HPAFII	viability after 27 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-5.786665063290419	[104]	[0,0,NaN]	-9	hSpCas9	negative selection	9557618
57752563	57752586	16	+	27869803	HPAFII	viability after 27 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-4.712423409903415	[203]	[2,4,NaN]	-9	hSpCas9	negative selection	9557619
57737252	57737275	16	-	27869803	HPAFII	viability after 15 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.08678082567942047	[139]	[264,64,NaN]	-1	hSpCas9	negative selection	9640063
57741784	57741807	16	-	27869803	HPAFII	viability after 15 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-0.9892757100478591	[66]	[92,0,NaN]	-7	hSpCas9	negative selection	9640064
57744415	57744438	16	-	27869803	HPAFII	viability after 15 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	0.42595360697152573	[129]	[376,69,NaN]	5	hSpCas9	negative selection	9640065
57750876	57750899	16	-	27869803	HPAFII	viability after 15 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-0.21770447482803862	[369]	[365,326,NaN]	-3	hSpCas9	negative selection	9640066
57751654	57751677	16	-	27869803	HPAFII	viability after 15 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-2.5512346563830928	[104]	[46,1,NaN]	-9	hSpCas9	negative selection	9640067
57752563	57752586	16	+	27869803	HPAFII	viability after 15 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-3.3738018158594056	[203]	[22,19,NaN]	-9	hSpCas9	negative selection	9640068
57737252	57737275	16	-	27869803	ASPC1	viability after 36 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	0.11044976725965283	[688]	[337,508,3]	1	hSpCas9	negative selection	9722512
57741784	57741807	16	-	27869803	ASPC1	viability after 36 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	0.2741714228938865	[228]	[228,6,73]	2	hSpCas9	negative selection	9722513
57744415	57744438	16	-	27869803	ASPC1	viability after 36 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.4543840612072657	[351]	[116,39,108]	-4	hSpCas9	negative selection	9722514
57750876	57750899	16	-	27869803	ASPC1	viability after 36 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	1.009353240933689	[1016]	[826,714,627]	8	hSpCas9	negative selection	9722515
57751654	57751677	16	-	27869803	ASPC1	viability after 36 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	0.01135662614773203	[224]	[173,25,53]	0	hSpCas9	negative selection	9722516
57752563	57752586	16	+	27869803	ASPC1	viability after 36 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-0.744988510443202	[467]	[110,138,53]	-6	hSpCas9	negative selection	9722517
57737252	57737275	16	-	27869803	PATU8988S	viability after 35 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.8351656845401708	[471]	[129,82,NaN]	-7	hSpCas9	negative selection	9804961
57741784	57741807	16	-	27869803	PATU8988S	viability after 35 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-2.436812869392028	[167]	[10,13,NaN]	-9	hSpCas9	negative selection	9804962
57744415	57744438	16	-	27869803	PATU8988S	viability after 35 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.9020397606068971	[282]	[57,63,NaN]	-7	hSpCas9	negative selection	9804963
57750876	57750899	16	-	27869803	PATU8988S	viability after 35 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	0.20471203191402165	[922]	[389,466,NaN]	2	hSpCas9	negative selection	9804964
57751654	57751677	16	-	27869803	PATU8988S	viability after 35 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-3.485251490913665	[221]	[0,14,NaN]	-9	hSpCas9	negative selection	9804965
57752563	57752586	16	+	27869803	PATU8988S	viability after 35 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-4.452465980863612	[462]	[15,0,NaN]	-9	hSpCas9	negative selection	9804966
57737252	57737275	16	-	27869803	PATU8988S	viability after 31 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.38866099515764896	[471]	[141,145,NaN]	-4	hSpCas9	negative selection	9887410
57741784	57741807	16	-	27869803	PATU8988S	viability after 31 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	-1.2877656498369578	[167]	[15,41,NaN]	-8	hSpCas9	negative selection	9887411
57744415	57744438	16	-	27869803	PATU8988S	viability after 31 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-0.2225339498644856	[282]	[68,131,NaN]	-3	hSpCas9	negative selection	9887412
57750876	57750899	16	-	27869803	PATU8988S	viability after 31 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	0.2724487528429683	[922]	[345,569,NaN]	3	hSpCas9	negative selection	9887413
57751654	57751677	16	-	27869803	PATU8988S	viability after 31 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-3.2229511924134853	[221]	[12,4,NaN]	-9	hSpCas9	negative selection	9887414
57752563	57752586	16	+	27869803	PATU8988S	viability after 31 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-2.7820201709001653	[462]	[32,18,NaN]	-9	hSpCas9	negative selection	9887415
57737252	57737275	16	-	27869803	HPAFII	viability after 35 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	-0.4987835899141331	[139]	[12,91,NaN]	-3	hSpCas9	negative selection	9969859
57741784	57741807	16	-	27869803	HPAFII	viability after 35 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	0.582374250456791	[66]	[94,0,NaN]	4	hSpCas9	negative selection	9969860
57744415	57744438	16	-	27869803	HPAFII	viability after 35 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-1.8840412640067363	[129]	[30,2,NaN]	-7	hSpCas9	negative selection	9969861
57750876	57750899	16	-	27869803	HPAFII	viability after 35 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-1.1460871685981404	[369]	[62,108,NaN]	-6	hSpCas9	negative selection	9969862
57751654	57751677	16	-	27869803	HPAFII	viability after 35 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-5.732156964669448	[104]	[0,0,NaN]	-9	hSpCas9	negative selection	9969863
57752563	57752586	16	+	27869803	HPAFII	viability after 35 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-6.690336788974821	[203]	[0,0,NaN]	-9	hSpCas9	negative selection	9969864
57737252	57737275	16	-	27869803	HPAFII	viability after 31 days	AGGCTGTCTTGGTGACCACAGGG	KATNB1	ENSG00000140854	0.3118412023255539	[139]	[86,108,NaN]	2	hSpCas9	negative selection	10052308
57741784	57741807	16	-	27869803	HPAFII	viability after 31 days	TGGGCTTGTTGATGGACCACAGG	KATNB1	ENSG00000140854	0.6341193553055644	[66]	[110,0,NaN]	4	hSpCas9	negative selection	10052309
57744415	57744438	16	-	27869803	HPAFII	viability after 31 days	TTGAGGCGGACGCTCTCCACTGG	KATNB1	ENSG00000140854	-1.7323781806073923	[129]	[20,22,NaN]	-7	hSpCas9	negative selection	10052310
57750876	57750899	16	-	27869803	HPAFII	viability after 31 days	CTACAAACTCGCCGTACGGGTGG	KATNB1	ENSG00000140854	-1.2298226268119365	[369]	[66,111,NaN]	-6	hSpCas9	negative selection	10052311
57751654	57751677	16	-	27869803	HPAFII	viability after 31 days	GCTGAACCGGAGACACCGCACGG	KATNB1	ENSG00000140854	-5.880874317990865	[104]	[0,0,NaN]	-9	hSpCas9	negative selection	10052312
57752563	57752586	16	+	27869803	HPAFII	viability after 31 days	GGTGGTGAGCTGCATCGAAGGGG	KATNB1	ENSG00000140854	-6.839054142296238	[203]	[0,0,NaN]	-9	hSpCas9	negative selection	10052313
57753457	57753480	16	-	28162770	P31FUJ	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.7182290315846205	[153]	[109]	-5	hSpCas9	negative selection	10177202
57756446	57756469	16	+	28162770	P31FUJ	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-1.1572511714072014	[92]	[48]	-7	hSpCas9	negative selection	10177203
57744399	57744422	16	+	28162770	P31FUJ	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.8304757568850891	[341]	[112]	-8	hSpCas9	negative selection	10177204
57744461	57744484	16	-	28162770	P31FUJ	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.3397174083308905	[83]	[77]	-3	hSpCas9	negative selection	10177205
57752545	57752568	16	+	28162770	P31FUJ	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-2.3857541272529774	[337]	[75]	-8	hSpCas9	negative selection	10177206
57753178	57753201	16	-	28162770	P31FUJ	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	0.4028575380145467	[232]	[361]	4	hSpCas9	negative selection	10177207
57753217	57753240	16	-	28162770	P31FUJ	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-0.39692158417548495	[92]	[82]	-4	hSpCas9	negative selection	10177208
57754964	57754987	16	-	28162770	P31FUJ	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-1.1803347845202432	[53]	[27]	-7	hSpCas9	negative selection	10177209
57755410	57755433	16	-	28162770	P31FUJ	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.3591186541957791	[166]	[152]	-3	hSpCas9	negative selection	10177210
57756376	57756399	16	-	28162770	P31FUJ	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-2.2456262447719624	[112]	[27]	-8	hSpCas9	negative selection	10177211
57753457	57753480	16	-	28162770	TF1	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10346568
57756446	57756469	16	+	28162770	TF1	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	NaN	[NaN]	[77]	1	hSpCas9	negative selection	10346569
57744399	57744422	16	+	28162770	TF1	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	NaN	[NaN]	[272]	1	hSpCas9	negative selection	10346570
57744461	57744484	16	-	28162770	TF1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10346571
57752545	57752568	16	+	28162770	TF1	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	NaN	[NaN]	[68]	1	hSpCas9	negative selection	10346572
57753178	57753201	16	-	28162770	TF1	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10346573
57753217	57753240	16	-	28162770	TF1	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	NaN	[NaN]	[72]	1	hSpCas9	negative selection	10346574
57754964	57754987	16	-	28162770	TF1	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	NaN	[NaN]	[52]	1	hSpCas9	negative selection	10346575
57755410	57755433	16	-	28162770	TF1	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10346576
57756376	57756399	16	-	28162770	TF1	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	NaN	[NaN]	[78]	1	hSpCas9	negative selection	10346577
57753457	57753480	16	-	28162770	SKM1	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-2.4409115306664995	[42]	[13]	-9	hSpCas9	negative selection	10515934
57756446	57756469	16	+	28162770	SKM1	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-2.237039197300849	[23]	[8]	-8	hSpCas9	negative selection	10515935
57744399	57744422	16	+	28162770	SKM1	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.1215619798809133	[111]	[90]	-7	hSpCas9	negative selection	10515936
57744461	57744484	16	-	28162770	SKM1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.4542699135215185	[30]	[19]	-7	hSpCas9	negative selection	10515937
57752545	57752568	16	+	28162770	SKM1	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-2.5064998722940763	[89]	[27]	-9	hSpCas9	negative selection	10515938
57753178	57753201	16	-	28162770	SKM1	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	0.06696698958925063	[80]	[149]	0	hSpCas9	negative selection	10515939
57753217	57753240	16	-	28162770	SKM1	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	1.3479233034203066	[9]	[44]	9	hSpCas9	negative selection	10515940
57754964	57754987	16	-	28162770	SKM1	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-0.08503610385579918	[11]	[19]	0	hSpCas9	negative selection	10515941
57755410	57755433	16	-	28162770	SKM1	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.3455636540790182	[45]	[63]	-3	hSpCas9	negative selection	10515942
57756376	57756399	16	-	28162770	SKM1	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-1.4542699135215185	[30]	[19]	-7	hSpCas9	negative selection	10515943
57753457	57753480	16	-	28162770	SKM1	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-2.4409115306664995	[42]	[13]	-9	hSpCas9	negative selection	10685300
57756446	57756469	16	+	28162770	SKM1	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-2.237039197300849	[23]	[8]	-8	hSpCas9	negative selection	10685301
57744399	57744422	16	+	28162770	SKM1	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.1215619798809133	[111]	[90]	-7	hSpCas9	negative selection	10685302
57744461	57744484	16	-	28162770	SKM1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.4542699135215185	[30]	[19]	-7	hSpCas9	negative selection	10685303
57752545	57752568	16	+	28162770	SKM1	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-2.5064998722940763	[89]	[27]	-9	hSpCas9	negative selection	10685304
57753178	57753201	16	-	28162770	SKM1	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	0.06696698958925063	[80]	[149]	0	hSpCas9	negative selection	10685305
57753217	57753240	16	-	28162770	SKM1	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	1.3479233034203066	[9]	[44]	9	hSpCas9	negative selection	10685306
57754964	57754987	16	-	28162770	SKM1	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-0.08503610385579918	[11]	[19]	0	hSpCas9	negative selection	10685307
57755410	57755433	16	-	28162770	SKM1	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.3455636540790182	[45]	[63]	-3	hSpCas9	negative selection	10685308
57756376	57756399	16	-	28162770	SKM1	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-1.4542699135215185	[30]	[19]	-7	hSpCas9	negative selection	10685309
57753457	57753480	16	-	28162770	PL21	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.028679076006560777	[149]	[63]	0	hSpCas9	negative selection	10854666
57756446	57756469	16	+	28162770	PL21	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-1.4145702296258882	[48]	[7]	-7	hSpCas9	negative selection	10854667
57744399	57744422	16	+	28162770	PL21	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-0.7887768863816637	[388]	[97]	-5	hSpCas9	negative selection	10854668
57744461	57744484	16	-	28162770	PL21	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.137730024267064	[90]	[17]	-6	hSpCas9	negative selection	10854669
57752545	57752568	16	+	28162770	PL21	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.618022062524867	[267]	[37]	-8	hSpCas9	negative selection	10854670
57753178	57753201	16	-	28162770	PL21	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.42279073643085646	[307]	[99]	-3	hSpCas9	negative selection	10854671
57753217	57753240	16	-	28162770	PL21	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-1.6960245745261402	[66]	[8]	-8	hSpCas9	negative selection	10854672
57754964	57754987	16	-	28162770	PL21	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	0.20013961448932038	[37]	[18]	1	hSpCas9	negative selection	10854673
57755410	57755433	16	-	28162770	PL21	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	0.3438750919507695	[104]	[57]	3	hSpCas9	negative selection	10854674
57756376	57756399	16	-	28162770	PL21	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-1.4403179988235393	[105]	[16]	-7	hSpCas9	negative selection	10854675
57753457	57753480	16	-	28162770	P31FUJ	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.7182290315846205	[153]	[109]	-5	hSpCas9	negative selection	11024032
57756446	57756469	16	+	28162770	P31FUJ	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-1.1572511714072014	[92]	[48]	-7	hSpCas9	negative selection	11024033
57744399	57744422	16	+	28162770	P31FUJ	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.8304757568850891	[341]	[112]	-8	hSpCas9	negative selection	11024034
57744461	57744484	16	-	28162770	P31FUJ	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.3397174083308905	[83]	[77]	-3	hSpCas9	negative selection	11024035
57752545	57752568	16	+	28162770	P31FUJ	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-2.3857541272529774	[337]	[75]	-8	hSpCas9	negative selection	11024036
57753178	57753201	16	-	28162770	P31FUJ	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	0.4028575380145467	[232]	[361]	4	hSpCas9	negative selection	11024037
57753217	57753240	16	-	28162770	P31FUJ	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-0.39692158417548495	[92]	[82]	-4	hSpCas9	negative selection	11024038
57754964	57754987	16	-	28162770	P31FUJ	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-1.1803347845202432	[53]	[27]	-7	hSpCas9	negative selection	11024039
57755410	57755433	16	-	28162770	P31FUJ	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.3591186541957791	[166]	[152]	-3	hSpCas9	negative selection	11024040
57756376	57756399	16	-	28162770	P31FUJ	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-2.2456262447719624	[112]	[27]	-8	hSpCas9	negative selection	11024041
57753457	57753480	16	-	28162770	OCIAML5	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-1.2894718831712955	[64]	[47]	-6	hSpCas9	negative selection	11193398
57756446	57756469	16	+	28162770	OCIAML5	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-1.0107643168830553	[47]	[42]	-6	hSpCas9	negative selection	11193399
57744399	57744422	16	+	28162770	OCIAML5	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-0.7479581675232583	[146]	[157]	-5	hSpCas9	negative selection	11193400
57744461	57744484	16	-	28162770	OCIAML5	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	0.6997290659219598	[43]	[128]	6	hSpCas9	negative selection	11193401
57752545	57752568	16	+	28162770	OCIAML5	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-3.964276074450022	[146]	[16]	-9	hSpCas9	negative selection	11193402
57753178	57753201	16	-	28162770	OCIAML5	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.35005685949815124	[172]	[244]	-2	hSpCas9	negative selection	11193403
57753217	57753240	16	-	28162770	OCIAML5	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-1.1058231631097803	[61]	[51]	-6	hSpCas9	negative selection	11193404
57754964	57754987	16	-	28162770	OCIAML5	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	1.860651477055532	[8]	[58]	9	hSpCas9	negative selection	11193405
57755410	57755433	16	-	28162770	OCIAML5	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	1.278330066391678	[36]	[161]	9	hSpCas9	negative selection	11193406
57756376	57756399	16	-	28162770	OCIAML5	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	0.11476656520080375	[65]	[128]	0	hSpCas9	negative selection	11193407
57753457	57753480	16	-	28162770	EOL1	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	0.10399554713135352	[301]	[170]	0	hSpCas9	negative selection	11362764
57756446	57756469	16	+	28162770	EOL1	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	1.2724710749908412	[54]	[69]	9	hSpCas9	negative selection	11362765
57744399	57744422	16	+	28162770	EOL1	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.0163249234672187	[740]	[192]	-6	hSpCas9	negative selection	11362766
57744461	57744484	16	-	28162770	EOL1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.6604147291506217	[155]	[51]	-5	hSpCas9	negative selection	11362767
57752545	57752568	16	+	28162770	EOL1	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.830339730592934	[539]	[79]	-8	hSpCas9	negative selection	11362768
57753178	57753201	16	-	28162770	EOL1	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.16781624657812488	[515]	[241]	-1	hSpCas9	negative selection	11362769
57753217	57753240	16	-	28162770	EOL1	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	1.100119336153989	[84]	[95]	8	hSpCas9	negative selection	11362770
57754964	57754987	16	-	28162770	EOL1	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	0.32047644790167373	[37]	[24]	3	hSpCas9	negative selection	11362771
57755410	57755433	16	-	28162770	EOL1	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.17605616936787127	[192]	[89]	-1	hSpCas9	negative selection	11362772
57756376	57756399	16	-	28162770	EOL1	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-1.100987320536603	[113]	[27]	-6	hSpCas9	negative selection	11362773
57753457	57753480	16	-	28162770	MOLM13	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.5014138212325046	[185]	[94]	-3	hSpCas9	negative selection	11532130
57756446	57756469	16	+	28162770	MOLM13	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-0.07839265101251747	[91]	[62]	0	hSpCas9	negative selection	11532131
57744399	57744422	16	+	28162770	MOLM13	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.2266976103510756	[491]	[151]	-6	hSpCas9	negative selection	11532132
57744461	57744484	16	-	28162770	MOLM13	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.3127975900509454	[133]	[38]	-6	hSpCas9	negative selection	11532133
57752545	57752568	16	+	28162770	MOLM13	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-4.198867210340225	[380]	[14]	-9	hSpCas9	negative selection	11532134
57753178	57753201	16	-	28162770	MOLM13	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.016833863538619376	[409]	[292]	0	hSpCas9	negative selection	11532135
57753217	57753240	16	-	28162770	MOLM13	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-0.7337444796250718	[68]	[29]	-4	hSpCas9	negative selection	11532136
57754964	57754987	16	-	28162770	MOLM13	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-0.7545030397918693	[69]	[29]	-4	hSpCas9	negative selection	11532137
57755410	57755433	16	-	28162770	MOLM13	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.9795695954266423	[119]	[43]	-5	hSpCas9	negative selection	11532138
57756376	57756399	16	-	28162770	MOLM13	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-1.5559573604097892	[121]	[29]	-6	hSpCas9	negative selection	11532139
57753457	57753480	16	-	28162770	HEL	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.6832474794613588	[177]	[70]	-4	hSpCas9	negative selection	11701496
57756446	57756469	16	+	28162770	HEL	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-0.6791892628870051	[104]	[41]	-4	hSpCas9	negative selection	11701497
57744399	57744422	16	+	28162770	HEL	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	0.2126260122594147	[480]	[356]	1	hSpCas9	negative selection	11701498
57744461	57744484	16	-	28162770	HEL	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	0.45179604928896155	[120]	[105]	4	hSpCas9	negative selection	11701499
57752545	57752568	16	+	28162770	HEL	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.199196321767392	[379]	[105]	-6	hSpCas9	negative selection	11701500
57753178	57753201	16	-	28162770	HEL	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.029573803823595757	[399]	[250]	0	hSpCas9	negative selection	11701501
57753217	57753240	16	-	28162770	HEL	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	0.3410831321392558	[52]	[42]	3	hSpCas9	negative selection	11701502
57754964	57754987	16	-	28162770	HEL	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	1.498348922665182	[20]	[37]	9	hSpCas9	negative selection	11701503
57755410	57755433	16	-	28162770	HEL	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.5796535893360911	[125]	[53]	-4	hSpCas9	negative selection	11701504
57756376	57756399	16	-	28162770	HEL	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-0.219757644249708	[99]	[54]	-1	hSpCas9	negative selection	11701505
57753457	57753480	16	-	28162770	MV411	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.4391963678332864	[168]	[104]	-3	hSpCas9	negative selection	11870862
57756446	57756469	16	+	28162770	MV411	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-1.03267036840996	[50]	[20]	-6	hSpCas9	negative selection	11870863
57744399	57744422	16	+	28162770	MV411	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.7718243513778575	[376]	[92]	-8	hSpCas9	negative selection	11870864
57744461	57744484	16	-	28162770	MV411	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	0.05218125938384155	[78]	[68]	0	hSpCas9	negative selection	11870865
57752545	57752568	16	+	28162770	MV411	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.460008956463376	[257]	[78]	-7	hSpCas9	negative selection	11870866
57753178	57753201	16	-	28162770	MV411	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.38936388145799894	[254]	[163]	-3	hSpCas9	negative selection	11870867
57753217	57753240	16	-	28162770	MV411	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-1.2909823640013505	[60]	[20]	-7	hSpCas9	negative selection	11870868
57754964	57754987	16	-	28162770	MV411	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-0.03009642474613372	[39]	[32]	0	hSpCas9	negative selection	11870869
57755410	57755433	16	-	28162770	MV411	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	0.3139329625696821	[105]	[110]	2	hSpCas9	negative selection	11870870
57756376	57756399	16	-	28162770	MV411	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-0.3498032797168176	[58]	[38]	-3	hSpCas9	negative selection	11870871
57753457	57753480	16	-	28162770	MONOMAC1	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.6306900245057445	[103]	[76]	-5	hSpCas9	negative selection	12040228
57756446	57756469	16	+	28162770	MONOMAC1	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	0.3088540826704036	[49]	[70]	3	hSpCas9	negative selection	12040229
57744399	57744422	16	+	28162770	MONOMAC1	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-1.2641510429180909	[263]	[125]	-7	hSpCas9	negative selection	12040230
57744461	57744484	16	-	28162770	MONOMAC1	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.2750393590608269	[56]	[26]	-7	hSpCas9	negative selection	12040231
57752545	57752568	16	+	28162770	MONOMAC1	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-1.7656049095300412	[174]	[58]	-8	hSpCas9	negative selection	12040232
57753178	57753201	16	-	28162770	MONOMAC1	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	0.5755526568373738	[167]	[286]	5	hSpCas9	negative selection	12040233
57753217	57753240	16	-	28162770	MONOMAC1	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-0.6945365065303706	[47]	[33]	-5	hSpCas9	negative selection	12040234
57754964	57754987	16	-	28162770	MONOMAC1	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-2.2476629201295215	[28]	[6]	-9	hSpCas9	negative selection	12040235
57755410	57755433	16	-	28162770	MONOMAC1	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	0.6960479490239344	[83]	[155]	6	hSpCas9	negative selection	12040236
57756376	57756399	16	-	28162770	MONOMAC1	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-0.8805631822642996	[52]	[32]	-6	hSpCas9	negative selection	12040237
57753457	57753480	16	-	28162770	OCIAML2	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-0.5059628983544419	[30]	[120]	-4	hSpCas9	negative selection	12209594
57756446	57756469	16	+	28162770	OCIAML2	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-2.956056652412403	[13]	[9]	-9	hSpCas9	negative selection	12209595
57744399	57744422	16	+	28162770	OCIAML2	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-2.0507265707915012	[73]	[98]	-8	hSpCas9	negative selection	12209596
57744461	57744484	16	-	28162770	OCIAML2	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-0.9087509376340465	[20]	[61]	-6	hSpCas9	negative selection	12209597
57752545	57752568	16	+	28162770	OCIAML2	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-3.356973043446594	[60]	[32]	-9	hSpCas9	negative selection	12209598
57753178	57753201	16	-	28162770	OCIAML2	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.2876249967558592	[60]	[276]	-2	hSpCas9	negative selection	12209599
57753217	57753240	16	-	28162770	OCIAML2	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-1.264178947774735	[12]	[29]	-7	hSpCas9	negative selection	12209600
57754964	57754987	16	-	28162770	OCIAML2	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-0.14870173035479883	[3]	[19]	-1	hSpCas9	negative selection	12209601
57755410	57755433	16	-	28162770	OCIAML2	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-0.08106301347943562	[24]	[130]	0	hSpCas9	negative selection	12209602
57756376	57756399	16	-	28162770	OCIAML2	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-1.019968416232596	[14]	[40]	-6	hSpCas9	negative selection	12209603
57753457	57753480	16	-	28162770	OCIAML3	viability	GGCGTTCTGGATCTCCGCGCGGG	KATNB1	ENSG00000140854	-2.672010152325436	[37]	[17]	-9	hSpCas9	negative selection	12378960
57756446	57756469	16	+	28162770	OCIAML3	viability	GGGTGTGGATATCAGCAGGGAGG	KATNB1	ENSG00000140854	-1.8455464073201275	[24]	[20]	-8	hSpCas9	negative selection	12378961
57744399	57744422	16	+	28162770	OCIAML3	viability	GACGGGCCACACATCCCCAGTGG	KATNB1	ENSG00000140854	-2.8923489148939097	[90]	[36]	-9	hSpCas9	negative selection	12378962
57744461	57744484	16	-	28162770	OCIAML3	viability	GATGGAGCCCGACTGAGAGCCGG	KATNB1	ENSG00000140854	-1.5115454801321901	[16]	[17]	-8	hSpCas9	negative selection	12378963
57752545	57752568	16	+	28162770	OCIAML3	viability	GGACCTGGAGAAGTTCCAGGTGG	KATNB1	ENSG00000140854	-2.2016902175454027	[95]	[62]	-8	hSpCas9	negative selection	12378964
57753178	57753201	16	-	28162770	OCIAML3	viability	GCAGTGGCTGTGCCAGGGGCCGG	KATNB1	ENSG00000140854	-0.013546531837947962	[106]	[319]	0	hSpCas9	negative selection	12378965
57753217	57753240	16	-	28162770	OCIAML3	viability	GCCGCTCATAGATGCGCCGGAGG	KATNB1	ENSG00000140854	-1.2985517567979916	[21]	[26]	-7	hSpCas9	negative selection	12378966
57754964	57754987	16	-	28162770	OCIAML3	viability	GGAACTGCACATCCATGGCAGGG	KATNB1	ENSG00000140854	-1.5065447990738239	[15]	[16]	-8	hSpCas9	negative selection	12378967
57755410	57755433	16	-	28162770	OCIAML3	viability	GCACCACACACATGGTGTCGTGG	KATNB1	ENSG00000140854	-1.1707962095996192	[43]	[58]	-7	hSpCas9	negative selection	12378968
57756376	57756399	16	-	28162770	OCIAML3	viability	CTGCAGGATCAGCTTCAGGGAGG	KATNB1	ENSG00000140854	-2.700922844240675	[27]	[12]	-9	hSpCas9	negative selection	12378969