Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3750
• Symbol:KCND1
• Description:potassium voltage-gated channel subfamily D member 1

DataSource: http://genomecrispr.dkfz.de/#!/results/KCND1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
48969371	48969394	X	+	26472758	Jiyoye	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.8739564558787154	[88]	[122]	6	hSpCas9	negative selection	81009
48970097	48970120	X	-	26472758	Jiyoye	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	1.6649731389735203	[22]	[54]	8	hSpCas9	negative selection	81010
48966968	48966991	X	-	26472758	Jiyoye	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.5313547927266034	[88]	[96]	4	hSpCas9	negative selection	81011
48969966	48969989	X	-	26472758	Jiyoye	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	1.480424363536512	[47]	[100]	8	hSpCas9	negative selection	81012
48969848	48969871	X	-	26472758	Jiyoye	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.8268893679941904	[76]	[102]	6	hSpCas9	negative selection	81013
48969815	48969838	X	-	26472758	Jiyoye	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-0.6372187378525801	[98]	[47]	-4	hSpCas9	negative selection	81014
48969796	48969819	X	-	26472758	Jiyoye	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-4.365414122391054	[81]	[2]	-9	hSpCas9	negative selection	81015
48969637	48969660	X	-	26472758	Jiyoye	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	-0.12925722528762396	[189]	[130]	-1	hSpCas9	negative selection	81016
48970188	48970211	X	+	26472758	Jiyoye	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	2.2906613727794487	[28]	[106]	9	hSpCas9	negative selection	81017
48970151	48970174	X	-	26472758	Jiyoye	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.29653131782188097	[148]	[137]	2	hSpCas9	negative selection	81018
48969371	48969394	X	+	26472758	KBM7	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.5040560836718153	[567,385]	[248,370]	5	hSpCas9	negative selection	272127
48970097	48970120	X	-	26472758	KBM7	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	0.6307464844653514	[236,299]	[221,177]	7	hSpCas9	negative selection	272128
48966968	48966991	X	-	26472758	KBM7	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.16040383066392405	[482,361]	[269,174]	1	hSpCas9	negative selection	272129
48969966	48969989	X	-	26472758	KBM7	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.16679240747669222	[557,264]	[184,232]	1	hSpCas9	negative selection	272130
48969848	48969871	X	-	26472758	KBM7	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	-0.02823365395141808	[777,594]	[308,317]	0	hSpCas9	negative selection	272131
48969815	48969838	X	-	26472758	KBM7	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.5606506403512238	[142,231]	[174,96]	6	hSpCas9	negative selection	272132
48969796	48969819	X	-	26472758	KBM7	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-0.9705748596275845	[248,171]	[43,54]	-6	hSpCas9	negative selection	272133
48969637	48969660	X	-	26472758	KBM7	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.4095975387547677	[576,460]	[434,220]	4	hSpCas9	negative selection	272134
48970188	48970211	X	+	26472758	KBM7	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	0.10042013362623448	[479,297]	[147,231]	1	hSpCas9	negative selection	272135
48970151	48970174	X	-	26472758	KBM7	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.4909640671027262	[772,869]	[524,569]	5	hSpCas9	negative selection	272136
48969371	48969394	X	+	26472758	Raji	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.737015085428484	[105]	[40]	7	hSpCas9	negative selection	463245
48970097	48970120	X	-	26472758	Raji	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	-2.2917875584462233	[210]	[9]	-9	hSpCas9	negative selection	463246
48966968	48966991	X	-	26472758	Raji	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.0940867127601417	[217]	[53]	0	hSpCas9	negative selection	463247
48969966	48969989	X	-	26472758	Raji	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.3789294410629108	[168]	[50]	3	hSpCas9	negative selection	463248
48969848	48969871	X	-	26472758	Raji	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	1.730016454060811	[251]	[193]	9	hSpCas9	negative selection	463249
48969815	48969838	X	-	26472758	Raji	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-0.13547298852256429	[70]	[14]	-1	hSpCas9	negative selection	463250
48969796	48969819	X	-	26472758	Raji	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-0.390867332154226	[112]	[19]	-3	hSpCas9	negative selection	463251
48969637	48969660	X	-	26472758	Raji	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	-0.8158352301389193	[310]	[40]	-6	hSpCas9	negative selection	463252
48970188	48970211	X	+	26472758	Raji	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-1.352048083263698	[252]	[22]	-7	hSpCas9	negative selection	463253
48970151	48970174	X	-	26472758	Raji	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	-0.16493411129453078	[342]	[70]	-1	hSpCas9	negative selection	463254
48969371	48969394	X	+	26472758	K562	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.7912814384527103	[242]	[354]	6	hSpCas9	negative selection	654363
48970097	48970120	X	-	26472758	K562	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	0.6241674769421515	[268]	[349]	5	hSpCas9	negative selection	654364
48966968	48966991	X	-	26472758	K562	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.24020647637953257	[342]	[341]	1	hSpCas9	negative selection	654365
48969966	48969989	X	-	26472758	K562	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.3357415125839138	[504]	[537]	2	hSpCas9	negative selection	654366
48969848	48969871	X	-	26472758	K562	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	1.0357241560595591	[593]	[1027]	8	hSpCas9	negative selection	654367
48969815	48969838	X	-	26472758	K562	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-0.7903466904942297	[251]	[122]	-5	hSpCas9	negative selection	654368
48969796	48969819	X	-	26472758	K562	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-0.8050499485978531	[266]	[128]	-5	hSpCas9	negative selection	654369
48969637	48969660	X	-	26472758	K562	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	-0.22439002805337765	[327]	[236]	-1	hSpCas9	negative selection	654370
48970188	48970211	X	+	26472758	K562	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.9857010556946119	[311]	[132]	-5	hSpCas9	negative selection	654371
48970151	48970174	X	-	26472758	K562	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.2989427338545201	[700]	[727]	2	hSpCas9	negative selection	654372
48962749	48962772	X	-	26627737	DLD1	viability	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	-0.1983543684804041	[492]	[110,82,196]	-2	hSpCas9	negative selection	845875
48966095	48966118	X	-	26627737	DLD1	viability	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.44399809206578095	[581]	[193,419,150]	4	hSpCas9	negative selection	845876
48966586	48966609	X	+	26627737	DLD1	viability	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.35349132457543425	[586]	[224,175,290]	3	hSpCas9	negative selection	845877
48967093	48967116	X	-	26627737	DLD1	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.2715928442572805	[760]	[161,270,408]	3	hSpCas9	negative selection	845878
48969138	48969161	X	+	26627737	DLD1	viability	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.40073763906548243	[1348]	[521,646,511]	4	hSpCas9	negative selection	845879
48969917	48969940	X	+	26627737	DLD1	viability	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.13478579207372476	[854]	[212,340,188]	-1	hSpCas9	negative selection	845880
48962749	48962772	X	-	26627737	GBM cells	viability after 5 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	-0.2504637491525411	[182]	[86,77]	-4	hSpCas9	negative selection	928190
48966095	48966118	X	-	26627737	GBM cells	viability after 5 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.7232146889972793	[265]	[214,255]	8	hSpCas9	negative selection	928191
48966586	48966609	X	+	26627737	GBM cells	viability after 5 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	-0.04997080938746018	[304]	[135,179]	-1	hSpCas9	negative selection	928192
48967093	48967116	X	-	26627737	GBM cells	viability after 5 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.1408566538069152	[330]	[149,171]	-2	hSpCas9	negative selection	928193
48969138	48969161	X	+	26627737	GBM cells	viability after 5 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.2676285738864135	[806]	[533,507]	4	hSpCas9	negative selection	928194
48969917	48969940	X	+	26627737	GBM cells	viability after 5 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	1.1057448590713927	[252]	[311,271]	9	hSpCas9	negative selection	928195
48962749	48962772	X	-	26627737	GBM cells	viability after 13 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.45737188072495505	[182]	[180,99]	6	hSpCas9	negative selection	1010505
48966095	48966118	X	-	26627737	GBM cells	viability after 13 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.7853307574437103	[265]	[213,276]	8	hSpCas9	negative selection	1010506
48966586	48966609	X	+	26627737	GBM cells	viability after 13 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.17053430647772283	[304]	[204,170]	2	hSpCas9	negative selection	1010507
48967093	48967116	X	-	26627737	GBM cells	viability after 13 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.007259695652185816	[330]	[181,175]	0	hSpCas9	negative selection	1010508
48969138	48969161	X	+	26627737	GBM cells	viability after 13 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.2106202199533429	[806]	[643,394]	2	hSpCas9	negative selection	1010509
48969917	48969940	X	+	26627737	GBM cells	viability after 13 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.9950494776469327	[252]	[309,243]	9	hSpCas9	negative selection	1010510
48962749	48962772	X	-	26627737	GBM cells	viability after 21 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.38233167618001457	[182]	[150,109]	4	hSpCas9	negative selection	1092820
48966095	48966118	X	-	26627737	GBM cells	viability after 21 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.4339653937321395	[265]	[414,367]	9	hSpCas9	negative selection	1092821
48966586	48966609	X	+	26627737	GBM cells	viability after 21 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	-0.0016478716054711406	[304]	[176,154]	0	hSpCas9	negative selection	1092822
48967093	48967116	X	-	26627737	GBM cells	viability after 21 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.14488109752197076	[330]	[202,194]	1	hSpCas9	negative selection	1092823
48969138	48969161	X	+	26627737	GBM cells	viability after 21 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.19653299672677993	[806]	[527,478]	2	hSpCas9	negative selection	1092824
48969917	48969940	X	+	26627737	GBM cells	viability after 21 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	1.2465578178402164	[252]	[322,328]	9	hSpCas9	negative selection	1092825
48962749	48962772	X	-	26627737	RPE1	viability after 9 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	1.89587991516989	[300]	[289,428]	8	hSpCas9	negative selection	1175135
48966095	48966118	X	-	26627737	RPE1	viability after 9 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.3206005701089993	[481]	[420,319]	7	hSpCas9	negative selection	1175136
48966586	48966609	X	+	26627737	RPE1	viability after 9 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	-0.32359077444000345	[843]	[218,200]	-2	hSpCas9	negative selection	1175137
48967093	48967116	X	-	26627737	RPE1	viability after 9 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.8921069854931931	[716]	[368,477]	6	hSpCas9	negative selection	1175138
48969138	48969161	X	+	26627737	RPE1	viability after 9 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.8139685604663862	[2113]	[1142,1189]	5	hSpCas9	negative selection	1175139
48969917	48969940	X	+	26627737	RPE1	viability after 9 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.5278872716347323	[452]	[162,257]	3	hSpCas9	negative selection	1175140
48962749	48962772	X	-	26627737	RPE1	viability after 12 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	2.0023417377980604	[300]	[408,233]	8	hSpCas9	negative selection	1257450
48966095	48966118	X	-	26627737	RPE1	viability after 12 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.3446646088221592	[481]	[290,368]	7	hSpCas9	negative selection	1257451
48966586	48966609	X	+	26627737	RPE1	viability after 12 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	-0.023163960949672102	[843]	[210,235]	0	hSpCas9	negative selection	1257452
48967093	48967116	X	-	26627737	RPE1	viability after 12 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.44102805132607914	[716]	[278,242]	3	hSpCas9	negative selection	1257453
48969138	48969161	X	+	26627737	RPE1	viability after 12 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.6901853987077677	[2113]	[946,883]	4	hSpCas9	negative selection	1257454
48969917	48969940	X	+	26627737	RPE1	viability after 12 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.3051308341747103	[452]	[60,244]	2	hSpCas9	negative selection	1257455
48962749	48962772	X	-	26627737	RPE1	viability after 15 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	1.871657575060576	[300]	[474,153]	8	hSpCas9	negative selection	1339765
48966095	48966118	X	-	26627737	RPE1	viability after 15 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.8925496116140555	[481]	[414,96]	5	hSpCas9	negative selection	1339766
48966586	48966609	X	+	26627737	RPE1	viability after 15 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.5390746420411949	[843]	[379,314]	3	hSpCas9	negative selection	1339767
48967093	48967116	X	-	26627737	RPE1	viability after 15 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.8040321472639118	[716]	[543,170]	5	hSpCas9	negative selection	1339768
48969138	48969161	X	+	26627737	RPE1	viability after 15 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.7142316219045899	[2113]	[975,985]	4	hSpCas9	negative selection	1339769
48969917	48969940	X	+	26627737	RPE1	viability after 15 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	1.1728215851377743	[452]	[209,364]	6	hSpCas9	negative selection	1339770
48962749	48962772	X	-	26627737	RPE1	viability after 18 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	2.106047986835499	[300]	[413,280]	8	hSpCas9	negative selection	1422080
48966095	48966118	X	-	26627737	RPE1	viability after 18 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.71483915776225	[481]	[484,364]	8	hSpCas9	negative selection	1422081
48966586	48966609	X	+	26627737	RPE1	viability after 18 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	-0.04976045685960355	[843]	[133,311]	0	hSpCas9	negative selection	1422082
48967093	48967116	X	-	26627737	RPE1	viability after 18 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.22247413114061376	[716]	[276,170]	1	hSpCas9	negative selection	1422083
48969138	48969161	X	+	26627737	RPE1	viability after 18 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.7798137712403603	[2113]	[964,994]	5	hSpCas9	negative selection	1422084
48969917	48969940	X	+	26627737	RPE1	viability after 18 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.5696557846778914	[452]	[135,229]	3	hSpCas9	negative selection	1422085
48962749	48962772	X	-	26627737	HeLa	viability after 8 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.9993072491839636	[148]	[222,65,120]	7	hSpCas9	negative selection	1504395
48966095	48966118	X	-	26627737	HeLa	viability after 8 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	-0.25651391355127173	[748]	[401,291,160]	-2	hSpCas9	negative selection	1504396
48966586	48966609	X	+	26627737	HeLa	viability after 8 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.24758381757907444	[468]	[177,281,251]	2	hSpCas9	negative selection	1504397
48967093	48967116	X	-	26627737	HeLa	viability after 8 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.22647231235437804	[482]	[256,190,288]	2	hSpCas9	negative selection	1504398
48969138	48969161	X	+	26627737	HeLa	viability after 8 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.2291774783928444	[1011]	[482,375,670]	2	hSpCas9	negative selection	1504399
48969917	48969940	X	+	26627737	HeLa	viability after 8 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.9269600105706232	[206]	[205,152,162]	7	hSpCas9	negative selection	1504400
48962749	48962772	X	-	26627737	HeLa	viability after 12 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.9399871048357591	[148]	[89,151,107]	7	hSpCas9	negative selection	1586710
48966095	48966118	X	-	26627737	HeLa	viability after 12 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	-0.14887477367844637	[748]	[486,114,258]	-1	hSpCas9	negative selection	1586711
48966586	48966609	X	+	26627737	HeLa	viability after 12 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.031761585801779846	[468]	[217,197,178]	0	hSpCas9	negative selection	1586712
48967093	48967116	X	-	26627737	HeLa	viability after 12 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.2077244539864458	[482]	[97,340,236]	1	hSpCas9	negative selection	1586713
48969138	48969161	X	+	26627737	HeLa	viability after 12 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.740757846056149	[1011]	[920,425,784]	6	hSpCas9	negative selection	1586714
48969917	48969940	X	+	26627737	HeLa	viability after 12 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	1.4666820359609263	[206]	[402,218,93]	8	hSpCas9	negative selection	1586715
48962749	48962772	X	-	26627737	HeLa	viability after 15 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	1.7577893901526718	[148]	[230,215,164]	9	hSpCas9	negative selection	1669025
48966095	48966118	X	-	26627737	HeLa	viability after 15 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	-0.8762949414629794	[748]	[159,140,199]	-6	hSpCas9	negative selection	1669026
48966586	48966609	X	+	26627737	HeLa	viability after 15 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.17389245671686787	[468]	[340,130,168]	1	hSpCas9	negative selection	1669027
48967093	48967116	X	-	26627737	HeLa	viability after 15 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.5292586927842221	[482]	[189,348,315]	4	hSpCas9	negative selection	1669028
48969138	48969161	X	+	26627737	HeLa	viability after 15 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.9206047263367245	[1011]	[895,493,961]	7	hSpCas9	negative selection	1669029
48969917	48969940	X	+	26627737	HeLa	viability after 15 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	1.8677765945443907	[206]	[333,453,119]	9	hSpCas9	negative selection	1669030
48962749	48962772	X	-	26627737	HeLa	viability after 18 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	1.7911123238637328	[148]	[168,172,164]	9	hSpCas9	negative selection	1751340
48966095	48966118	X	-	26627737	HeLa	viability after 18 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	-0.8469305906774147	[748]	[112,117,199]	-6	hSpCas9	negative selection	1751341
48966586	48966609	X	+	26627737	HeLa	viability after 18 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.1440510512786704	[468]	[222,104,168]	1	hSpCas9	negative selection	1751342
48967093	48967116	X	-	26627737	HeLa	viability after 18 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.5529296975791784	[482]	[134,290,315]	4	hSpCas9	negative selection	1751343
48969138	48969161	X	+	26627737	HeLa	viability after 18 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.9226739132892625	[1011]	[608,401,961]	7	hSpCas9	negative selection	1751344
48969917	48969940	X	+	26627737	HeLa	viability after 18 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	1.8594520154229066	[206]	[218,377,119]	9	hSpCas9	negative selection	1751345
48962749	48962772	X	-	26627737	HCT116	viability after 6 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.799280587841253	[515]	[77,175]	4	hSpCas9	negative selection	1833655
48966095	48966118	X	-	26627737	HCT116	viability after 6 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	-1.3797287446149784	[1166]	[123,40]	-7	hSpCas9	negative selection	1833656
48966586	48966609	X	+	26627737	HCT116	viability after 6 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	-0.3441699089766075	[979]	[199,77]	-2	hSpCas9	negative selection	1833657
48967093	48967116	X	-	26627737	HCT116	viability after 6 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.8661224663214064	[1057]	[618,128]	5	hSpCas9	negative selection	1833658
48969138	48969161	X	+	26627737	HCT116	viability after 6 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.8618173298734335	[1786]	[467,533]	5	hSpCas9	negative selection	1833659
48969917	48969940	X	+	26627737	HCT116	viability after 6 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.7851126941011223	[1088]	[479,192]	4	hSpCas9	negative selection	1833660
48962749	48962772	X	-	26627737	HCT116	viability after 8 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	-0.22296215261470825	[343]	[128,142,213]	-3	hSpCas9	negative selection	1915970
48966095	48966118	X	-	26627737	HCT116	viability after 8 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.8014722294778214	[252]	[190,211,323]	7	hSpCas9	negative selection	1915971
48966586	48966609	X	+	26627737	HCT116	viability after 8 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.24592761676849717	[302]	[240,176,176]	2	hSpCas9	negative selection	1915972
48967093	48967116	X	-	26627737	HCT116	viability after 8 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.18987140850904083	[436]	[249,251,320]	2	hSpCas9	negative selection	1915973
48969138	48969161	X	+	26627737	HCT116	viability after 8 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	-0.08136393022589394	[1143]	[669,543,574]	-1	hSpCas9	negative selection	1915974
48969917	48969940	X	+	26627737	HCT116	viability after 8 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.09126534997731234	[427]	[203,251,207]	-1	hSpCas9	negative selection	1915975
48962749	48962772	X	-	26627737	HCT116	viability after 9 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.06495062609009014	[515]	[161,129]	0	hSpCas9	negative selection	1998285
48966095	48966118	X	-	26627737	HCT116	viability after 9 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	-0.739348147949378	[1166]	[270,119]	-5	hSpCas9	negative selection	1998286
48966586	48966609	X	+	26627737	HCT116	viability after 9 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.5865389296242	[979]	[216,531]	4	hSpCas9	negative selection	1998287
48967093	48967116	X	-	26627737	HCT116	viability after 9 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.07483298919449732	[1057]	[184,333]	0	hSpCas9	negative selection	1998288
48969138	48969161	X	+	26627737	HCT116	viability after 9 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.8221181532810735	[1786]	[417,1179]	6	hSpCas9	negative selection	1998289
48969917	48969940	X	+	26627737	HCT116	viability after 9 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.3506804092407523	[1088]	[427,69]	-2	hSpCas9	negative selection	1998290
48962749	48962772	X	-	26627737	HCT116	viability after 12 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	-0.08738599249472781	[343]	[195,161,149]	-1	hSpCas9	negative selection	2080600
48966095	48966118	X	-	26627737	HCT116	viability after 12 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.0524492444178286	[252]	[203,333,296]	8	hSpCas9	negative selection	2080601
48966586	48966609	X	+	26627737	HCT116	viability after 12 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.630998533869178	[302]	[329,144,254]	6	hSpCas9	negative selection	2080602
48967093	48967116	X	-	26627737	HCT116	viability after 12 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.5589246040074749	[436]	[445,234,321]	5	hSpCas9	negative selection	2080603
48969138	48969161	X	+	26627737	HCT116	viability after 12 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	-0.05790363917925134	[1143]	[704,599,416]	0	hSpCas9	negative selection	2080604
48969917	48969940	X	+	26627737	HCT116	viability after 12 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.24287873377420893	[427]	[146,230,196]	-3	hSpCas9	negative selection	2080605
48962749	48962772	X	-	26627737	HCT116	viability after 15 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	-0.08492224903481545	[343]	[213,147,199]	-1	hSpCas9	negative selection	2162915
48966095	48966118	X	-	26627737	HCT116	viability after 15 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.4816804050944345	[252]	[298,388,514]	9	hSpCas9	negative selection	2162916
48966586	48966609	X	+	26627737	HCT116	viability after 15 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.5049256957490946	[302]	[274,287,181]	5	hSpCas9	negative selection	2162917
48967093	48967116	X	-	26627737	HCT116	viability after 15 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.5596977652460342	[436]	[505,224,394]	5	hSpCas9	negative selection	2162918
48969138	48969161	X	+	26627737	HCT116	viability after 15 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	-0.22201287209772635	[1143]	[826,501,394]	-2	hSpCas9	negative selection	2162919
48969917	48969940	X	+	26627737	HCT116	viability after 15 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.14943720302360824	[427]	[224,280,159]	-1	hSpCas9	negative selection	2162920
48962749	48962772	X	-	26627737	HCT116	viability after 18 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.7041845092384271	[343]	[452,194,164]	6	hSpCas9	negative selection	2245230
48966095	48966118	X	-	26627737	HCT116	viability after 18 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.1670424211089743	[252]	[230,180,424]	8	hSpCas9	negative selection	2245231
48966586	48966609	X	+	26627737	HCT116	viability after 18 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.364975718782284	[302]	[223,130,215]	3	hSpCas9	negative selection	2245232
48967093	48967116	X	-	26627737	HCT116	viability after 18 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.39207932601824236	[436]	[234,180,428]	3	hSpCas9	negative selection	2245233
48969138	48969161	X	+	26627737	HCT116	viability after 18 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.14239290992417697	[1143]	[885,482,463]	1	hSpCas9	negative selection	2245234
48969917	48969940	X	+	26627737	HCT116	viability after 18 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.06827128878652133	[427]	[204,228,215]	0	hSpCas9	negative selection	2245235
48969621	48969644	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGACCTGCGTGCAGAGCCGCGG	KCND1	ENSG00000102057	-0.35794526045083064	[3,4]	[3,1]	-5	hSpCas9	positive selection	2996667
48969978	48970001	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTAGAAGTTCAGCACATGGCGG	KCND1	ENSG00000102057	-0.31008945802696897	[2,2]	[2,1]	-4	hSpCas9	positive selection	2996668
48969697	48969720	X	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCACATAGTAGAAAACGAGGG	KCND1	ENSG00000102057	0.6161052836235978	[3,2]	[5,3]	9	hSpCas9	positive selection	2996669
48969966	48969989	X	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.9202910119083388	[2,2]	[1,0]	-9	hSpCas9	positive selection	2996670
48969621	48969644	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGACCTGCGTGCAGAGCCGCGG	KCND1	ENSG00000102057	0.7678989582505458	[3,3]	[5,4]	9	hSpCas9	positive selection	3064525
48969978	48970001	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTAGAAGTTCAGCACATGGCGG	KCND1	ENSG00000102057	-0.07591478042032204	[2,2]	[2,1]	-1	hSpCas9	positive selection	3064526
48969697	48969720	X	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCACATAGTAGAAAACGAGGG	KCND1	ENSG00000102057	-0.6288043915273612	[3,3]	[2,0]	-8	hSpCas9	positive selection	3064527
48969966	48969989	X	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.28173961890639243	[2,2]	[2,0]	-4	hSpCas9	positive selection	3064528
48969406	48969429		-	24336571	A375	resistance to PLX after 7 days	CCCAAGAACGACGATGTCTCTGG	KCND1	ENSG00000102057	-0.31039756822987946	[18,14]	[12,13]	-8	hSpCas9	positive selection	3122295
48969659	48969682		-	24336571	A375	resistance to PLX after 7 days	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.21238764941179372	[9,9]	[12,9]	6	hSpCas9	positive selection	3122296
48966958	48966981		+	24336571	A375	resistance to PLX after 7 days	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	-0.08809288010878219	[9,10]	[8,10]	-3	hSpCas9	positive selection	3122297
48966943	48966966		-	24336571	A375	resistance to PLX after 7 days	TGACAAGCGCCGAGCACAGCAGG	KCND1	ENSG00000102057	-0.28356321020855974	[9,11]	[8,7]	-8	hSpCas9	positive selection	3122298
48969406	48969429		-	24336571	A375	resistance to PLX after 14 days	CCCAAGAACGACGATGTCTCTGG	KCND1	ENSG00000102057	-0.11698232430485095	[17,18]	[5,9]	-1	hSpCas9	positive selection	3180088
48969659	48969682		-	24336571	A375	resistance to PLX after 14 days	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.3313667206339216	[6,11]	[5,4]	3	hSpCas9	positive selection	3180089
48966958	48966981		+	24336571	A375	resistance to PLX after 14 days	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.34954479746512607	[10,6]	[5,3]	3	hSpCas9	positive selection	3180090
48966943	48966966		-	24336571	A375	resistance to PLX after 14 days	TGACAAGCGCCGAGCACAGCAGG	KCND1	ENSG00000102057	0.28971212532775364	[6,12]	[5,4]	3	hSpCas9	positive selection	3180091
48969406	48969429		-	24336571	A375	viability after 7 days	CCCAAGAACGACGATGTCTCTGG	KCND1	ENSG00000102057	0.8619536633728155	[9]	[18,14]	9	hSpCas9	negative selection	3237881
48969659	48969682		-	24336571	A375	viability after 7 days	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.44607965488860235	[7]	[9,9]	6	hSpCas9	negative selection	3237882
48966958	48966981		+	24336571	A375	viability after 7 days	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.314443661677213	[8]	[9,10]	5	hSpCas9	negative selection	3237883
48966943	48966966		-	24336571	A375	viability after 7 days	TGACAAGCGCCGAGCACAGCAGG	KCND1	ENSG00000102057	0.32963941235959476	[8]	[9,11]	5	hSpCas9	negative selection	3237884
48969406	48969429		-	24336571	A375	viability after 14 days	CCCAAGAACGACGATGTCTCTGG	KCND1	ENSG00000102057	0.9965443350775816	[9]	[17,18]	9	hSpCas9	negative selection	3295674
48969659	48969682		-	24336571	A375	viability after 14 days	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.41119045691556927	[7]	[6,11]	5	hSpCas9	negative selection	3295675
48966958	48966981		+	24336571	A375	viability after 14 days	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.14935542618823078	[8]	[10,6]	2	hSpCas9	negative selection	3295676
48966943	48966966		-	24336571	A375	viability after 14 days	TGACAAGCGCCGAGCACAGCAGG	KCND1	ENSG00000102057	0.20368584787286176	[8]	[6,12]	2	hSpCas9	negative selection	3295677
48966802	48966825	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	-1.5305763479455965	[441,441]	[0,0]	-8	hSpCas9	positive selection	3375149
48967093	48967116	X	-	27383988	293T	resistance to West Nile virus (flavivirus)	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.009460329249066228	[153,153]	[0,0]	0	hSpCas9	positive selection	3375150
48966769	48966792	X	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	-0.8301366298045043	[271,271]	[0,0]	-5	hSpCas9	positive selection	3375151
48969620	48969643	X	+	26780180	HT29	viability (Avana library 4 designs)	AGGACCTGCGTGCAGAGCCGCGG	KCND1	ENSG00000102057	1.53680337882536	[]	[]	6	hSpCas9	negative selection	3434069
48969977	48970000	X	+	26780180	HT29	viability (Avana library 4 designs)	GGTAGAAGTTCAGCACATGGCGG	KCND1	ENSG00000102057	2.09915586090464	[]	[]	7	hSpCas9	negative selection	3434070
48969696	48969719	X	+	26780180	HT29	viability (Avana library 4 designs)	GGTCACATAGTAGAAAACGAGGG	KCND1	ENSG00000102057	2.06369268337747	[]	[]	7	hSpCas9	negative selection	3434071
48969966	48969989	X	-	26780180	HT29	viability (Avana library 4 designs)	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	2.43752188402929	[]	[]	8	hSpCas9	negative selection	3434072
48969696	48969719	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCACATAGTAGAAAACGAGGG	KCND1	ENSG00000102057	-6.66583004526774	[]	[]	-6	hSpCas9	negative selection	3520998
48969620	48969643	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGGACCTGCGTGCAGAGCCGCGG	KCND1	ENSG00000102057	5.3673184055838	[]	[]	8	hSpCas9	negative selection	3520999
48969966	48969989	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-4.36103335249915	[]	[]	-5	hSpCas9	negative selection	3521000
48969977	48970000	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTAGAAGTTCAGCACATGGCGG	KCND1	ENSG00000102057	3.11524260302671	[]	[]	5	hSpCas9	negative selection	3521001
48969989	48970012	X	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCACATGGCGGAACATGTCAGGG	KCND1	ENSG00000102057	-3.25380394661206	[]	[]	-4	hSpCas9	negative selection	3521002
48969971	48969994	X	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGCTGAACTTCTACCGAACGG	KCND1	ENSG00000102057	-1.29196795707104	[]	[]	-1	hSpCas9	negative selection	3521003
48969696	48969719	X	+	26780180	A375	viability (Avana lentiGuide)	GGTCACATAGTAGAAAACGAGGG	KCND1	ENSG00000102057	-2.40340069968433	[]	[]	-4	hSpCas9	negative selection	3629657
48969620	48969643	X	+	26780180	A375	viability (Avana lentiGuide)	AGGACCTGCGTGCAGAGCCGCGG	KCND1	ENSG00000102057	-0.808057545651654	[]	[]	-1	hSpCas9	negative selection	3629658
48969966	48969989	X	-	26780180	A375	viability (Avana lentiGuide)	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	1.23621834128671	[]	[]	1	hSpCas9	negative selection	3629659
48969977	48970000	X	+	26780180	A375	viability (Avana lentiGuide)	GGTAGAAGTTCAGCACATGGCGG	KCND1	ENSG00000102057	-4.17542353472018	[]	[]	-7	hSpCas9	negative selection	3629660
48969989	48970012	X	+	26780180	A375	viability (Avana lentiGuide)	GCACATGGCGGAACATGTCAGGG	KCND1	ENSG00000102057	6.2689090659621	[]	[]	5	hSpCas9	negative selection	3629661
48969971	48969994	X	-	26780180	A375	viability (Avana lentiGuide)	TGTGCTGAACTTCTACCGAACGG	KCND1	ENSG00000102057	-2.70477775038264	[]	[]	-5	hSpCas9	negative selection	3629662
48969696	48969719	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCACATAGTAGAAAACGAGGG	KCND1	ENSG00000102057	-0.4287978103680887	[5]	[4,2]	-6	hSpCas9	positive selection	3738316
48969620	48969643	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGACCTGCGTGCAGAGCCGCGG	KCND1	ENSG00000102057	0.2686476587006439	[5]	[7,6]	7	hSpCas9	positive selection	3738317
48969966	48969989	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.16963505503235932	[3]	[4,2]	-3	hSpCas9	positive selection	3738318
48969977	48970000	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTAGAAGTTCAGCACATGGCGG	KCND1	ENSG00000102057	-0.3956726797538256	[4]	[4,1]	-5	hSpCas9	positive selection	3738319
48969989	48970012	X	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCACATGGCGGAACATGTCAGGG	KCND1	ENSG00000102057	-0.07252295842229256	[4]	[4,3]	-1	hSpCas9	positive selection	3738320
48969971	48969994	X	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGCTGAACTTCTACCGAACGG	KCND1	ENSG00000102057	0.007744183067205368	[6]	[6,5]	0	hSpCas9	positive selection	3738321
48969696	48969719	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCACATAGTAGAAAACGAGGG	KCND1	ENSG00000102057	-0.10003512040380208	[4]	[2,4]	-1	hSpCas9	positive selection	3846923
48969620	48969643	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGACCTGCGTGCAGAGCCGCGG	KCND1	ENSG00000102057	-0.3081530600747456	[5]	[4,2]	-4	hSpCas9	positive selection	3846924
48969966	48969989	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.4569323831190445	[4]	[3,0]	-5	hSpCas9	positive selection	3846925
48969977	48970000	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTAGAAGTTCAGCACATGGCGG	KCND1	ENSG00000102057	0.22796757376947108	[4]	[4,4]	6	hSpCas9	positive selection	3846926
48969989	48970012	X	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCACATGGCGGAACATGTCAGGG	KCND1	ENSG00000102057	0.11889080449059922	[4]	[4,4]	2	hSpCas9	positive selection	3846927
48969971	48969994	X	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGCTGAACTTCTACCGAACGG	KCND1	ENSG00000102057	0.19446393530019299	[6]	[6,6]	5	hSpCas9	positive selection	3846928
48969660	48969683	X	+	26780180	A375	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.07974468973722	[]	[]	-3	hSpCas9	negative selection	3952934
48966769	48966792	X	+	26780180	A375	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.300731889566246	[]	[]	0	hSpCas9	negative selection	3952935
48969659	48969682	X	-	26780180	A375	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.781965240040801	[]	[]	3	hSpCas9	negative selection	3952936
48966958	48966981	X	+	26780180	A375	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	-0.22735453528751	[]	[]	-6	hSpCas9	negative selection	3952937
48967093	48967116	X	-	26780180	A375	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.651639551813169	[]	[]	2	hSpCas9	negative selection	3952938
48966802	48966825	X	+	26780180	A375	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.206146614153755	[]	[]	0	hSpCas9	negative selection	3952939
48969660	48969683	X	+	26780180	HT29	viability (GeCKOv2 library)	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	1.00729532632465	[]	[]	4	hSpCas9	negative selection	4060900
48966769	48966792	X	+	26780180	HT29	viability (GeCKOv2 library)	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	1.40610904704476	[]	[]	7	hSpCas9	negative selection	4060901
48969659	48969682	X	-	26780180	HT29	viability (GeCKOv2 library)	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.850318549211431	[]	[]	3	hSpCas9	negative selection	4060902
48966958	48966981	X	+	26780180	HT29	viability (GeCKOv2 library)	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	-0.175171680448672	[]	[]	-5	hSpCas9	negative selection	4060903
48967093	48967116	X	-	26780180	HT29	viability (GeCKOv2 library)	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.798666617218219	[]	[]	3	hSpCas9	negative selection	4060904
48966802	48966825	X	+	26780180	HT29	viability (GeCKOv2 library)	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	1.05333695244914	[]	[]	5	hSpCas9	negative selection	4060905
48969406	48969429	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCAAGAACGACGATGTCTCTGG	KCND1	ENSG00000102057	0.03348896227534495	[3]	[1,2]	0	hSpCas9	positive selection	4146061
48969659	48969682	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.06512878198807409	[2]	[1,2]	1	hSpCas9	positive selection	4146062
48966958	48966981	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.21089367826573202	[2]	[2,2]	5	hSpCas9	positive selection	4146063
48966943	48966966	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGACAAGCGCCGAGCACAGCAGG	KCND1	ENSG00000102057	0.14650802820700254	[3]	[2,2]	4	hSpCas9	positive selection	4146064
48969406	48969429	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCAAGAACGACGATGTCTCTGG	KCND1	ENSG00000102057	0.7435833059844049	[3]	[2,0,0,3]	5	hSpCas9	positive selection	4210083
48969659	48969682	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.8812041861717566	[3]	[0,0,1,4]	6	hSpCas9	positive selection	4210084
48966958	48966981	X	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.8118584447679889	[2]	[4,0,4,0]	5	hSpCas9	positive selection	4210085
48966943	48966966	X	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGACAAGCGCCGAGCACAGCAGG	KCND1	ENSG00000102057	0.8924610623647163	[3]	[2,0,4,3]	6	hSpCas9	positive selection	4210086
48969660	48969683	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.010682625320293238	[3]	[3,2]	0	hSpCas9	positive selection	4277852
48969659	48969682	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.0905711470984999	[3]	[3,2]	1	hSpCas9	positive selection	4277853
48966958	48966981	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.12286916284771077	[3]	[3,2]	2	hSpCas9	positive selection	4277854
48966802	48966825	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.028904246263383115	[3]	[3,2]	0	hSpCas9	positive selection	4342108
48967093	48967116	X	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.21890626793919105	[3]	[3,2]	4	hSpCas9	positive selection	4342109
48966769	48966792	X	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.31410006164991877	[3]	[3,3]	6	hSpCas9	positive selection	4342110
48969474	48969496	X	+	27760321	OCIAML3	viability	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	0.4277151738685947	[652,538]	[479,811]	5	hSpCas9	negative selection	4411197
48969586	48969608	X	+	27760321	OCIAML3	viability	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	0.04456683184379717	[608,641]	[416,624]	0	hSpCas9	negative selection	4411198
48969878	48969900	X	+	27760321	OCIAML3	viability	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	-0.34995730848771045	[366,292]	[87,348]	-4	hSpCas9	negative selection	4411199
48969966	48969988	X	-	27760321	OCIAML3	viability	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.18647984315278376	[695,579]	[518,625]	2	hSpCas9	negative selection	4411200
48970110	48970132	X	-	27760321	OCIAML3	viability	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.35753874976644257	[597,587]	[491,730]	4	hSpCas9	negative selection	4411201
48969474	48969496	X	+	27760321	OCIAML2	viability	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	0.514516172056532	[652,538]	[597,800]	7	hSpCas9	negative selection	4494660
48969586	48969608	X	+	27760321	OCIAML2	viability	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	0.3495800033835519	[608,641]	[526,807]	5	hSpCas9	negative selection	4494661
48969878	48969900	X	+	27760321	OCIAML2	viability	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.4946563636594533	[366,292]	[344,411]	6	hSpCas9	negative selection	4494662
48969966	48969988	X	-	27760321	OCIAML2	viability	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.5096673827193844	[695,579]	[644,845]	7	hSpCas9	negative selection	4494663
48970110	48970132	X	-	27760321	OCIAML2	viability	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.4871119715778673	[597,587]	[592,780]	6	hSpCas9	negative selection	4494664
48969474	48969496	X	+	27760321	MV411	viability	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	1.1445212918436312	[652,538]	[998,664]	8	hSpCas9	negative selection	4578123
48969586	48969608	X	+	27760321	MV411	viability	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	1.0617118057813766	[608,641]	[998,666]	7	hSpCas9	negative selection	4578124
48969878	48969900	X	+	27760321	MV411	viability	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	-0.13840852524410086	[366,292]	[45,422]	-1	hSpCas9	negative selection	4578125
48969966	48969988	X	-	27760321	MV411	viability	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.8542377182701516	[695,579]	[920,512]	6	hSpCas9	negative selection	4578126
48970110	48970132	X	-	27760321	MV411	viability	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.7603306192861992	[597,587]	[626,720]	5	hSpCas9	negative selection	4578127
48969474	48969496	X	+	27760321	HL60	viability	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	1.1962558551239089	[652,538]	[994,1232]	9	hSpCas9	negative selection	4661586
48969586	48969608	X	+	27760321	HL60	viability	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	-0.21079497277878945	[608,641]	[390,499]	-2	hSpCas9	negative selection	4661587
48969878	48969900	X	+	27760321	HL60	viability	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.2737155265057915	[366,292]	[305,342]	3	hSpCas9	negative selection	4661588
48969966	48969988	X	-	27760321	HL60	viability	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.09317600815685478	[695,579]	[573,531]	1	hSpCas9	negative selection	4661589
48970110	48970132	X	-	27760321	HL60	viability	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	-0.05587653612442922	[597,587]	[407,529]	0	hSpCas9	negative selection	4661590
48969474	48969496	X	+	27760321	HT1080	viability	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	1.8042521301888121	[538,420]	[706,624]	8	hSpCas9	negative selection	4745049
48969586	48969608	X	+	27760321	HT1080	viability	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	0.38646185933441757	[641,500]	[88,525]	2	hSpCas9	negative selection	4745050
48969878	48969900	X	+	27760321	HT1080	viability	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	1.2025640649579683	[292,228]	[382,81]	6	hSpCas9	negative selection	4745051
48969966	48969988	X	-	27760321	HT1080	viability	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	1.4092830819250763	[579,452]	[367,741]	7	hSpCas9	negative selection	4745052
48970110	48970132	X	-	27760321	HT1080	viability	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	-0.9496374775067697	[587,458]	[96,119]	-4	hSpCas9	negative selection	4745053
48969474	48969496	X	+	27760321	HT29	viability after 7 days	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	-0.20994956273223325	[538,420]	[607,608,397]	-3	hSpCas9	negative selection	4828512
48969586	48969608	X	+	27760321	HT29	viability after 7 days	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	-0.07669695675970611	[641,500]	[677,694,712]	-1	hSpCas9	negative selection	4828513
48969878	48969900	X	+	27760321	HT29	viability after 7 days	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.15541912099175403	[292,228]	[453,233,441]	2	hSpCas9	negative selection	4828514
48969966	48969988	X	-	27760321	HT29	viability after 7 days	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.15593511954860118	[579,452]	[594,526,662]	-2	hSpCas9	negative selection	4828515
48970110	48970132	X	-	27760321	HT29	viability after 7 days	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.2069896519339005	[587,458]	[820,549,958]	3	hSpCas9	negative selection	4828516
48969474	48969496	X	+	27760321	HT29	viability after 25 days	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	-0.12729694357597443	[538,420]	[476,541,486]	-1	hSpCas9	negative selection	4911975
48969586	48969608	X	+	27760321	HT29	viability after 25 days	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	-0.14651301442165954	[641,500]	[418,460,935]	-1	hSpCas9	negative selection	4911976
48969878	48969900	X	+	27760321	HT29	viability after 25 days	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.5093003243381089	[292,228]	[517,412,325]	5	hSpCas9	negative selection	4911977
48969966	48969988	X	-	27760321	HT29	viability after 25 days	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.8575711737730518	[579,452]	[410,229,330]	-6	hSpCas9	negative selection	4911978
48970110	48970132	X	-	27760321	HT29	viability after 25 days	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.30396242689680664	[587,458]	[597,649,1002]	3	hSpCas9	negative selection	4911979
48969474	48969496	X	+	27760321	HT29	viability after 22 days	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	-0.22572741525216689	[538,420]	[566,499,352]	-2	hSpCas9	negative selection	4995438
48969586	48969608	X	+	27760321	HT29	viability after 22 days	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	-0.4715691064803378	[641,500]	[248,451,736]	-4	hSpCas9	negative selection	4995439
48969878	48969900	X	+	27760321	HT29	viability after 22 days	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.4303904559098852	[292,228]	[374,310,535]	4	hSpCas9	negative selection	4995440
48969966	48969988	X	-	27760321	HT29	viability after 22 days	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.35134069368786647	[579,452]	[636,356,404]	-3	hSpCas9	negative selection	4995441
48970110	48970132	X	-	27760321	HT29	viability after 22 days	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	-0.11121094521165403	[587,458]	[653,499,523]	-1	hSpCas9	negative selection	4995442
48969474	48969496	X	+	27760321	HT29	viability after 19 days	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	0.38156146530726476	[538,420]	[723,571,844]	3	hSpCas9	negative selection	5078901
48969586	48969608	X	+	27760321	HT29	viability after 19 days	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	-0.18906722370133988	[641,500]	[461,727,519]	-2	hSpCas9	negative selection	5078902
48969878	48969900	X	+	27760321	HT29	viability after 19 days	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.6062544959921377	[292,228]	[465,356,537]	6	hSpCas9	negative selection	5078903
48969966	48969988	X	-	27760321	HT29	viability after 19 days	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.451990440411743	[579,452]	[480,644,183]	-4	hSpCas9	negative selection	5078904
48970110	48970132	X	-	27760321	HT29	viability after 19 days	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.053614571058651306	[587,458]	[425,653,757]	0	hSpCas9	negative selection	5078905
48969474	48969496	X	+	27760321	HT29	viability after 16 days	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	-0.2234921814649403	[538,420]	[519,288,580]	-3	hSpCas9	negative selection	5162364
48969586	48969608	X	+	27760321	HT29	viability after 16 days	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	0.09322838003335332	[641,500]	[461,502,1064]	1	hSpCas9	negative selection	5162365
48969878	48969900	X	+	27760321	HT29	viability after 16 days	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.18700677444362618	[292,228]	[491,384,133]	2	hSpCas9	negative selection	5162366
48969966	48969988	X	-	27760321	HT29	viability after 16 days	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.5176841423794325	[579,452]	[677,242,319]	-5	hSpCas9	negative selection	5162367
48970110	48970132	X	-	27760321	HT29	viability after 16 days	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.36224895882518426	[587,458]	[552,661,1026]	4	hSpCas9	negative selection	5162368
48969474	48969496	X	+	27760321	HT29	viability after 13 days	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	-0.16006206129593276	[538,420]	[439,637,421]	-2	hSpCas9	negative selection	5245827
48969586	48969608	X	+	27760321	HT29	viability after 13 days	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	-0.3047010903585046	[641,500]	[415,461,720]	-4	hSpCas9	negative selection	5245828
48969878	48969900	X	+	27760321	HT29	viability after 13 days	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.10807759522700033	[292,228]	[302,364,311]	1	hSpCas9	negative selection	5245829
48969966	48969988	X	-	27760321	HT29	viability after 13 days	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.6472886888015006	[579,452]	[424,414,311]	-6	hSpCas9	negative selection	5245830
48970110	48970132	X	-	27760321	HT29	viability after 13 days	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	-0.0223002955766759	[587,458]	[578,719,500]	0	hSpCas9	negative selection	5245831
48969474	48969496	X	+	27760321	HT29	viability after 10 days	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	0.051894868225106305	[538,420]	[846,444,567]	0	hSpCas9	negative selection	5329290
48969586	48969608	X	+	27760321	HT29	viability after 10 days	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	-0.12671002277241916	[641,500]	[595,868,504]	-2	hSpCas9	negative selection	5329291
48969878	48969900	X	+	27760321	HT29	viability after 10 days	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.5452502618380176	[292,228]	[282,768,384]	7	hSpCas9	negative selection	5329292
48969966	48969988	X	-	27760321	HT29	viability after 10 days	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.3095242479693612	[579,452]	[833,418,309]	-4	hSpCas9	negative selection	5329293
48970110	48970132	X	-	27760321	HT29	viability after 10 days	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	-0.023928176072085527	[587,458]	[690,630,606]	0	hSpCas9	negative selection	5329294
48969474	48969496	X	+	27760321	MOLM13	viability	GAGGCTCATGACACTCCGCAGG	KCND1	ENSG00000102057	0.4328875503357298	[652,538]	[399,495]	3	hSpCas9	negative selection	5412753
48969586	48969608	X	+	27760321	MOLM13	viability	TGTGGGAAGCGTTCGCCACAGG	KCND1	ENSG00000102057	0.6366293516148043	[608,641]	[394,684]	4	hSpCas9	negative selection	5412754
48969878	48969900	X	+	27760321	MOLM13	viability	AGCAGTCACCGACTAGCTCGGG	KCND1	ENSG00000102057	0.1842783479792215	[366,292]	[212,207]	1	hSpCas9	negative selection	5412755
48969966	48969988	X	-	27760321	MOLM13	viability	GAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	1.855513971015549	[695,579]	[2343,405]	9	hSpCas9	negative selection	5412756
48970110	48970132	X	-	27760321	MOLM13	viability	CGGACGGCGCTTTGAGACTTGG	KCND1	ENSG00000102057	0.22192998873236297	[597,587]	[542,261]	1	hSpCas9	negative selection	5412757
48971357	48971380	X	+	27661255	K562	viability	GGGAGTTGGGTGTGTCTCCAGGG	KCND1	ENSG00000102057	0.09520529884275471	[708,785]	[681,597]	3	dCas9-KRAB	negative selection	5487870
48971402	48971425	X	+	27661255	K562	viability	GGAAGCTGGCAGGAGACGCCGGG	KCND1	ENSG00000102057	-0.03617465914155127	[1102,1015]	[811,838]	-1	dCas9-KRAB	negative selection	5487871
48969660	48969683	X	+	27260156	BXPC3	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.2252011386078524	[891]	[1148,1096,1079,1009]	5	hSpCas9	negative selection	5550312
48969659	48969682	X	-	27260156	BXPC3	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.2902420952681665	[565]	[757,619,800,712]	6	hSpCas9	negative selection	5550313
48966958	48966981	X	+	27260156	BXPC3	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.539990262332412	[942]	[1191,1493,1436,1650]	9	hSpCas9	negative selection	5550314
48966802	48966825	X	+	27260156	BXPC3	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.04309860250092845	[781]	[600,874,986,939]	0	hSpCas9	negative selection	5614568
48967093	48967116	X	-	27260156	BXPC3	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.07285527013222137	[693]	[788,645,831,788]	1	hSpCas9	negative selection	5614569
48966769	48966792	X	+	27260156	BXPC3	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.20558691709437993	[678]	[810,783,639,1063]	4	hSpCas9	negative selection	5614570
48969660	48969683	X	+	27260156	A673	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.18490194496243118	[891]	[895,904,885,1083]	-4	hSpCas9	negative selection	5671563
48969659	48969682	X	-	27260156	A673	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.19235815187894745	[565]	[924,743,626,830]	4	hSpCas9	negative selection	5671564
48966958	48966981	X	+	27260156	A673	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.3830854815834013	[942]	[1611,1325,1433,1555]	8	hSpCas9	negative selection	5671565
48966802	48966825	X	+	27260156	A673	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.2642134743777802	[781]	[1259,1061,1016,1190]	6	hSpCas9	negative selection	5735819
48967093	48967116	X	-	27260156	A673	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.13314417846797533	[693]	[1016,808,886,957]	3	hSpCas9	negative selection	5735820
48966769	48966792	X	+	27260156	A673	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.1553895117195212	[678]	[905,897,905,920]	3	hSpCas9	negative selection	5735821
48969660	48969683	X	+	27260156	A375	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.3095930938373973	[891]	[1345,1279,1225,1304]	4	hSpCas9	negative selection	5792814
48969659	48969682	X	-	27260156	A375	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.250709186844081	[565]	[915,688,761,765]	3	hSpCas9	negative selection	5792815
48966958	48966981	X	+	27260156	A375	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.6569608943125795	[942]	[1597,2221,1769,1450]	8	hSpCas9	negative selection	5792816
48966802	48966825	X	+	27260156	A375	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.6195024032968119	[781]	[1493,1540,1296,1306]	8	hSpCas9	negative selection	5857070
48967093	48967116	X	-	27260156	A375	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.12581424527125895	[693]	[563,1369,914,764]	1	hSpCas9	negative selection	5857071
48966769	48966792	X	+	27260156	A375	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.19133256589651204	[678]	[805,883,1158,780]	2	hSpCas9	negative selection	5857072
48969660	48969683	X	+	27260156	COLO741	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.24006239237538773	[891]	[987,986,922]	-5	hSpCas9	negative selection	5914065
48969659	48969682	X	-	27260156	COLO741	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.23142035392895455	[565]	[921,777,850]	5	hSpCas9	negative selection	5914066
48966958	48966981	X	+	27260156	COLO741	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	-0.24593975705656967	[942]	[1147,993,921]	-5	hSpCas9	negative selection	5914067
48966802	48966825	X	+	27260156	COLO741	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.1754130558422322	[781]	[1238,1251,916]	4	hSpCas9	negative selection	5978321
48967093	48967116	X	-	27260156	COLO741	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.11472890487245702	[693]	[1077,919,894]	2	hSpCas9	negative selection	5978322
48966769	48966792	X	+	27260156	COLO741	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.19690393776382342	[678]	[915,1083,975]	4	hSpCas9	negative selection	5978323
48969660	48969683	X	+	27260156	CAL120	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.3931248928718736	[891]	[713,1033,768]	-5	hSpCas9	negative selection	6035316
48969659	48969682	X	-	27260156	CAL120	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.09720334579593765	[565]	[885,926,471]	1	hSpCas9	negative selection	6035317
48966958	48966981	X	+	27260156	CAL120	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.18541766165703644	[942]	[1733,1343,990]	2	hSpCas9	negative selection	6035318
48966802	48966825	X	+	27260156	CAL120	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.09011575406086436	[781]	[1285,950,909]	1	hSpCas9	negative selection	6099572
48967093	48967116	X	-	27260156	CAL120	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.28371126144136677	[693]	[537,563,994]	-4	hSpCas9	negative selection	6099573
48966769	48966792	X	+	27260156	CAL120	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.1657495766163808	[678]	[1095,858,910]	2	hSpCas9	negative selection	6099574
48969660	48969683	X	+	27260156	CADOES1	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.17338357827512452	[891]	[618,898,824,594]	-3	hSpCas9	negative selection	6156567
48969659	48969682	X	-	27260156	CADOES1	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.05771704558872087	[565]	[499,572,513,606]	1	hSpCas9	negative selection	6156568
48966958	48966981	X	+	27260156	CADOES1	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.15602559361077395	[942]	[862,1138,891,1016]	2	hSpCas9	negative selection	6156569
48966802	48966825	X	+	27260156	CADOES1	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.33057463370098605	[781]	[809,984,841,1025]	5	hSpCas9	negative selection	6220823
48967093	48967116	X	-	27260156	CADOES1	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.29562989520403365	[693]	[349,757,480,514]	-5	hSpCas9	negative selection	6220824
48966769	48966792	X	+	27260156	CADOES1	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.28462928964437306	[678]	[729,816,764,764]	5	hSpCas9	negative selection	6220825
48969660	48969683	X	+	27260156	EWS502	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.1753076785401153	[891]	[652,932,880,899]	-3	hSpCas9	negative selection	6277818
48969659	48969682	X	-	27260156	EWS502	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.11107880703349632	[565]	[359,729,614,933]	2	hSpCas9	negative selection	6277819
48966958	48966981	X	+	27260156	EWS502	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.19596300616376716	[942]	[1099,1093,1383,993]	3	hSpCas9	negative selection	6277820
48966802	48966825	X	+	27260156	EWS502	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.12191517513534733	[781]	[946,724,970,965]	2	hSpCas9	negative selection	6342074
48967093	48967116	X	-	27260156	EWS502	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.19133136582866306	[693]	[703,553,478,843]	-3	hSpCas9	negative selection	6342075
48966769	48966792	X	+	27260156	EWS502	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.19646602415718217	[678]	[548,1044,926,795]	3	hSpCas9	negative selection	6342076
48969660	48969683	X	+	27260156	EW8	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.14500087575100307	[891]	[700,918,482,545]	-3	hSpCas9	negative selection	6399069
48969659	48969682	X	-	27260156	EW8	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	-0.45133758253597356	[565]	[351,353,304,336]	-7	hSpCas9	negative selection	6399070
48966958	48966981	X	+	27260156	EW8	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.39327063370511417	[942]	[1126,1078,981,841]	7	hSpCas9	negative selection	6399071
48966802	48966825	X	+	27260156	EW8	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.4361861034881336	[781]	[1038,906,690,838]	7	hSpCas9	negative selection	6463325
48967093	48967116	X	-	27260156	EW8	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.15163915410294115	[693]	[586,557,477,414]	-3	hSpCas9	negative selection	6463326
48966769	48966792	X	+	27260156	EW8	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.3075338193946052	[678]	[747,794,497,719]	5	hSpCas9	negative selection	6463327
48969660	48969683	X	+	27260156	CORL105	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.01241750990083157	[891]	[1140,872,978,1213]	0	hSpCas9	negative selection	6520320
48969659	48969682	X	-	27260156	CORL105	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.4084141664083137	[565]	[796,767,1185,813]	7	hSpCas9	negative selection	6520321
48966958	48966981	X	+	27260156	CORL105	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.40706402628280536	[942]	[1497,1222,1839,1358]	7	hSpCas9	negative selection	6520322
48966802	48966825	X	+	27260156	CORL105	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.36180504946336467	[781]	[1296,1072,1360,1009]	6	hSpCas9	negative selection	6584576
48967093	48967116	X	-	27260156	CORL105	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.028940257649612056	[693]	[1100,691,947,605]	0	hSpCas9	negative selection	6584577
48966769	48966792	X	+	27260156	CORL105	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.06278563045668117	[678]	[783,801,927,820]	1	hSpCas9	negative selection	6584578
48969660	48969683	X	+	27260156	HS294T	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.6210006980975132	[891]	[435,763,430,481]	7	hSpCas9	negative selection	6641571
48969659	48969682	X	-	27260156	HS294T	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.2973280770223334	[565]	[287,238,192,370]	4	hSpCas9	negative selection	6641572
48966958	48966981	X	+	27260156	HS294T	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.8722279746663355	[942]	[748,441,524,1007]	9	hSpCas9	negative selection	6641573
48966802	48966825	X	+	27260156	HS294T	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.4295944802703664	[781]	[342,444,364,493]	6	hSpCas9	negative selection	6705827
48967093	48967116	X	-	27260156	HS294T	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.2723032172617801	[693]	[357,325,242,372]	3	hSpCas9	negative selection	6705828
48966769	48966792	X	+	27260156	HS294T	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.219654747206804	[678]	[235,295,275,443]	3	hSpCas9	negative selection	6705829
48969660	48969683	X	+	27260156	HCC44	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.02586132498840099	[891]	[1380,779,1051,960]	0	hSpCas9	negative selection	6762822
48969659	48969682	X	-	27260156	HCC44	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.24100877711861585	[565]	[797,715,844,687]	4	hSpCas9	negative selection	6762823
48966958	48966981	X	+	27260156	HCC44	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.47751808274218055	[942]	[1277,1248,2021,1485]	7	hSpCas9	negative selection	6762824
48966802	48966825	X	+	27260156	HCC44	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.39996417997983014	[781]	[1466,1022,1005,1181]	6	hSpCas9	negative selection	6827078
48967093	48967116	X	-	27260156	HCC44	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.009338941928240696	[693]	[680,729,895,860]	0	hSpCas9	negative selection	6827079
48966769	48966792	X	+	27260156	HCC44	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.46303868130540016	[678]	[1023,801,1405,1085]	7	hSpCas9	negative selection	6827080
48969660	48969683	X	+	27260156	G402	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.19354114361122288	[891]	[1096,797,1022,899]	-2	hSpCas9	negative selection	6884073
48969659	48969682	X	-	27260156	G402	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.3507619100610108	[565]	[627,951,1108,801]	4	hSpCas9	negative selection	6884074
48966958	48966981	X	+	27260156	G402	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.37814903470372396	[942]	[1387,1710,1906,991]	5	hSpCas9	negative selection	6884075
48966802	48966825	X	+	27260156	G402	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.804212077599467	[781]	[1500,1468,1561,2070]	8	hSpCas9	negative selection	6948329
48967093	48967116	X	-	27260156	G402	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.05153367030715672	[693]	[920,1000,752,846]	0	hSpCas9	negative selection	6948330
48966769	48966792	X	+	27260156	G402	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.238635803007052	[678]	[891,1200,941,876]	3	hSpCas9	negative selection	6948331
48969660	48969683	X	+	27260156	L33	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.27102397217646956	[891]	[668,293,491,788]	-6	hSpCas9	negative selection	7005324
48969659	48969682	X	-	27260156	L33	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.18474622824294	[565]	[525,312,388,666]	4	hSpCas9	negative selection	7005325
48966958	48966981	X	+	27260156	L33	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.22281743877617233	[942]	[935,498,722,1101]	5	hSpCas9	negative selection	7005326
48966802	48966825	X	+	27260156	L33	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.2633567216049494	[781]	[954,329,578,1070]	5	hSpCas9	negative selection	7069580
48967093	48967116	X	-	27260156	L33	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.024607283726655216	[693]	[747,239,425,809]	0	hSpCas9	negative selection	7069581
48966769	48966792	X	+	27260156	L33	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.038787756002150564	[678]	[619,313,445,695]	0	hSpCas9	negative selection	7069582
48969660	48969683	X	+	27260156	K562	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.5864961204742983	[891]	[1760,1332,1370,428]	7	hSpCas9	negative selection	7126575
48969659	48969682	X	-	27260156	K562	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	-0.022329393470761988	[565]	[462,719,501,320]	0	hSpCas9	negative selection	7126576
48966958	48966981	X	+	27260156	K562	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.6782851550873068	[942]	[1613,1790,1151,892]	8	hSpCas9	negative selection	7126577
48966802	48966825	X	+	27260156	K562	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.2399127362919492	[781]	[454,1330,1065,461]	3	hSpCas9	negative selection	7190831
48967093	48967116	X	-	27260156	K562	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.29472656175759615	[693]	[819,1181,351,698]	3	hSpCas9	negative selection	7190832
48966769	48966792	X	+	27260156	K562	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.2979847468013431	[678]	[1002,890,595,524]	4	hSpCas9	negative selection	7190833
48969660	48969683	X	+	27260156	HT29	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.08154590649515037	[891]	[1122,1303,859,856]	-2	hSpCas9	negative selection	7247826
48969659	48969682	X	-	27260156	HT29	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.0020488851357226	[565]	[598,805,622,721]	0	hSpCas9	negative selection	7247827
48966958	48966981	X	+	27260156	HT29	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.34533482090343903	[942]	[1760,1525,1377,1209]	6	hSpCas9	negative selection	7247828
48966802	48966825	X	+	27260156	HT29	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.16523073345583406	[781]	[1068,1042,1225,932]	3	hSpCas9	negative selection	7312082
48967093	48967116	X	-	27260156	HT29	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.2578901503746376	[693]	[839,685,659,646]	-5	hSpCas9	negative selection	7312083
48966769	48966792	X	+	27260156	HT29	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.28829171930133013	[678]	[1223,895,880,1027]	5	hSpCas9	negative selection	7312084
48969660	48969683	X	+	27260156	MHHES1	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.072721589598573	[891]	[1131,1469,987,737]	1	hSpCas9	negative selection	7369077
48969659	48969682	X	-	27260156	MHHES1	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.3017493171211963	[565]	[791,744,907,697]	5	hSpCas9	negative selection	7369078
48966958	48966981	X	+	27260156	MHHES1	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.14269678828352128	[942]	[1672,1550,1016,644]	2	hSpCas9	negative selection	7369079
48966802	48966825	X	+	27260156	MHHES1	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.38431942841172795	[781]	[1343,976,1464,861]	7	hSpCas9	negative selection	7433333
48967093	48967116	X	-	27260156	MHHES1	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.3828428536312345	[693]	[1138,1042,1136,802]	7	hSpCas9	negative selection	7433334
48966769	48966792	X	+	27260156	MHHES1	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.1991317634730606	[678]	[1078,721,808,886]	3	hSpCas9	negative selection	7433335
48969660	48969683	X	+	27260156	MEWO	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.1492655311177623	[891]	[847,715,711]	-3	hSpCas9	negative selection	7490328
48969659	48969682	X	-	27260156	MEWO	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.06680049983381559	[565]	[700,575,414]	1	hSpCas9	negative selection	7490329
48966958	48966981	X	+	27260156	MEWO	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.4919314211608399	[942]	[1537,922,1319]	8	hSpCas9	negative selection	7490330
48966802	48966825	X	+	27260156	MEWO	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.09009193513394131	[781]	[852,669,827]	2	hSpCas9	negative selection	7554584
48967093	48967116	X	-	27260156	MEWO	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.06024624711614246	[693]	[526,614,859]	1	hSpCas9	negative selection	7554585
48966769	48966792	X	+	27260156	MEWO	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.13728363847185765	[678]	[923,594,620]	3	hSpCas9	negative selection	7554586
48969660	48969683	X	+	27260156	LNCAPCLONEFGC	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.24331925760194528	[891]	[844,944,1123,938]	4	hSpCas9	negative selection	7611579
48969659	48969682	X	-	27260156	LNCAPCLONEFGC	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.4351388256511261	[565]	[682,672,767,660]	6	hSpCas9	negative selection	7611580
48966958	48966981	X	+	27260156	LNCAPCLONEFGC	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.3623176581481826	[942]	[992,1054,1498,908]	6	hSpCas9	negative selection	7611581
48966802	48966825	X	+	27260156	LNCAPCLONEFGC	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.5409423391254407	[781]	[990,840,1406,951]	8	hSpCas9	negative selection	7675835
48967093	48967116	X	-	27260156	LNCAPCLONEFGC	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.3295023811363186	[693]	[639,832,820,869]	5	hSpCas9	negative selection	7675836
48966769	48966792	X	+	27260156	LNCAPCLONEFGC	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.5717330162274962	[678]	[950,765,1006,954]	8	hSpCas9	negative selection	7675837
48969660	48969683	X	+	27260156	PANC0327	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.04798075246836009	[891]	[909,663,519,995]	0	hSpCas9	negative selection	7732830
48969659	48969682	X	-	27260156	PANC0327	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.25597298937780905	[565]	[767,647,546,445]	4	hSpCas9	negative selection	7732831
48966958	48966981	X	+	27260156	PANC0327	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.20278313115476232	[942]	[849,717,1284,1025]	3	hSpCas9	negative selection	7732832
48966802	48966825	X	+	27260156	PANC0327	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.030406810005667695	[781]	[741,315,800,1031]	0	hSpCas9	negative selection	7797086
48967093	48967116	X	-	27260156	PANC0327	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.2899473910943342	[693]	[655,802,657,882]	4	hSpCas9	negative selection	7797087
48966769	48966792	X	+	27260156	PANC0327	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.4973301770142856	[678]	[930,555,1308,654]	7	hSpCas9	negative selection	7797088
48969660	48969683	X	+	27260156	NCIH2009	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.10918373957720429	[891]	[1746,1236,1127]	1	hSpCas9	negative selection	7854081
48969659	48969682	X	-	27260156	NCIH2009	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.5858807957322729	[565]	[1394,1017,1189]	7	hSpCas9	negative selection	7854082
48966958	48966981	X	+	27260156	NCIH2009	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.15311633261097612	[942]	[1737,1331,1378]	2	hSpCas9	negative selection	7854083
48966802	48966825	X	+	27260156	NCIH2009	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.4320998015285995	[781]	[1495,1480,1446]	6	hSpCas9	negative selection	7918337
48967093	48967116	X	-	27260156	NCIH2009	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.32597481891624347	[693]	[1310,1167,1184]	4	hSpCas9	negative selection	7918338
48966769	48966792	X	+	27260156	NCIH2009	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.10582645210491215	[678]	[1432,1039,668]	1	hSpCas9	negative selection	7918339
48969660	48969683	X	+	27260156	NCIH1373	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.26549216154789457	[891]	[2155,890,1121,207]	2	hSpCas9	negative selection	7975332
48969659	48969682	X	-	27260156	NCIH1373	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	1.1165332129978236	[565]	[1597,1063,1576,345]	9	hSpCas9	negative selection	7975333
48966958	48966981	X	+	27260156	NCIH1373	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.47983217366956765	[942]	[1523,1266,1727,364]	5	hSpCas9	negative selection	7975334
48966802	48966825	X	+	27260156	NCIH1373	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.9971460880692016	[781]	[2253,1269,1881,448]	8	hSpCas9	negative selection	8039588
48967093	48967116	X	-	27260156	NCIH1373	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.13656451977546274	[693]	[423,917,691,190]	-1	hSpCas9	negative selection	8039589
48966769	48966792	X	+	27260156	NCIH1373	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.14288783491410084	[678]	[1120,637,787,230]	1	hSpCas9	negative selection	8039590
48969660	48969683	X	+	27260156	PATU8902	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.6022223980095679	[891]	[2788,1933,1058,1957]	6	hSpCas9	negative selection	8096583
48969659	48969682	X	-	27260156	PATU8902	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	1.136196669730948	[565]	[1239,2584,1245,2014]	9	hSpCas9	negative selection	8096584
48966958	48966981	X	+	27260156	PATU8902	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	1.2458003360576515	[942]	[3633,2670,2821,3408]	9	hSpCas9	negative selection	8096585
48966802	48966825	X	+	27260156	PATU8902	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.9579398408239079	[781]	[2242,1290,2497,2335]	9	hSpCas9	negative selection	8160839
48967093	48967116	X	-	27260156	PATU8902	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.4443014188822827	[693]	[947,1175,1593,1483]	4	hSpCas9	negative selection	8160840
48966769	48966792	X	+	27260156	PATU8902	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	1.0838958809653394	[678]	[2665,2093,1083,2440]	9	hSpCas9	negative selection	8160841
48969660	48969683	X	+	27260156	PANC1	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.09662400173006136	[891]	[668,995,668,597]	-1	hSpCas9	negative selection	8217834
48969659	48969682	X	-	27260156	PANC1	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.2582854396232683	[565]	[570,682,636,465]	4	hSpCas9	negative selection	8217835
48966958	48966981	X	+	27260156	PANC1	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.2054171439887127	[942]	[832,1490,981,588]	3	hSpCas9	negative selection	8217836
48966802	48966825	X	+	27260156	PANC1	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	-0.010764412751246955	[781]	[610,1035,459,629]	0	hSpCas9	negative selection	8282090
48967093	48967116	X	-	27260156	PANC1	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.27880628111933947	[693]	[513,1084,750,625]	4	hSpCas9	negative selection	8282091
48966769	48966792	X	+	27260156	PANC1	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.3266294132405395	[678]	[757,803,912,493]	5	hSpCas9	negative selection	8282092
48969660	48969683	X	+	27260156	PANC0813	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.05511478727120123	[891]	[1000,1237,1033,1071]	0	hSpCas9	negative selection	8339085
48969659	48969682	X	-	27260156	PANC0813	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.34494275958465465	[565]	[907,914,842,722]	5	hSpCas9	negative selection	8339086
48966958	48966981	X	+	27260156	PANC0813	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.4955981307003039	[942]	[1676,1351,1619,1603]	7	hSpCas9	negative selection	8339087
48966802	48966825	X	+	27260156	PANC0813	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.324562359871962	[781]	[1083,1013,1444,1056]	5	hSpCas9	negative selection	8403341
48967093	48967116	X	-	27260156	PANC0813	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.27647438371437727	[693]	[1157,957,994,859]	4	hSpCas9	negative selection	8403342
48966769	48966792	X	+	27260156	PANC0813	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.18417974816215776	[678]	[1094,762,933,851]	3	hSpCas9	negative selection	8403343
48969660	48969683	X	+	27260156	RDES	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.04309721682739365	[891]	[803,853,1229,1152]	0	hSpCas9	negative selection	8460336
48969659	48969682	X	-	27260156	RDES	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.14164358442166824	[565]	[554,781,707,854]	2	hSpCas9	negative selection	8460337
48966958	48966981	X	+	27260156	RDES	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.39522156148982357	[942]	[1096,1424,1599,1652]	6	hSpCas9	negative selection	8460338
48966802	48966825	X	+	27260156	RDES	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.47236880269062165	[781]	[1056,1172,1372,1429]	7	hSpCas9	negative selection	8524592
48967093	48967116	X	-	27260156	RDES	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.027056710658455607	[693]	[692,670,816,990]	0	hSpCas9	negative selection	8524593
48966769	48966792	X	+	27260156	RDES	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.3763523393948941	[678]	[744,1207,1092,1020]	6	hSpCas9	negative selection	8524594
48969660	48969683	X	+	27260156	PC3	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.16496143466528534	[891]	[744,1065,1429,901]	3	hSpCas9	negative selection	8581587
48969659	48969682	X	-	27260156	PC3	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.2530560282074317	[565]	[389,640,1303,664]	5	hSpCas9	negative selection	8581588
48966958	48966981	X	+	27260156	PC3	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.49409640736286	[942]	[642,1226,2348,1693]	8	hSpCas9	negative selection	8581589
48966802	48966825	X	+	27260156	PC3	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.2095572076638177	[781]	[504,897,1629,952]	4	hSpCas9	negative selection	8645843
48967093	48967116	X	-	27260156	PC3	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.17442708832901088	[693]	[377,792,1388,920]	4	hSpCas9	negative selection	8645844
48966769	48966792	X	+	27260156	PC3	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.03896667967723688	[678]	[410,706,1214,710]	0	hSpCas9	negative selection	8645845
48969660	48969683	X	+	27260156	PATU8988T	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.21368165056771726	[891]	[662,668,663,990]	-4	hSpCas9	negative selection	8702838
48969659	48969682	X	-	27260156	PATU8988T	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	-0.17723423437124936	[565]	[450,599,446,444]	-3	hSpCas9	negative selection	8702839
48966958	48966981	X	+	27260156	PATU8988T	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.6100071199566051	[942]	[1078,1627,1472,1404]	8	hSpCas9	negative selection	8702840
48966802	48966825	X	+	27260156	PATU8988T	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.005962543635412487	[781]	[915,767,527,832]	0	hSpCas9	negative selection	8767094
48967093	48967116	X	-	27260156	PATU8988T	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.2273977733351099	[693]	[688,1014,559,910]	4	hSpCas9	negative selection	8767095
48966769	48966792	X	+	27260156	PATU8988T	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.09668957379733889	[678]	[574,740,494,1027]	1	hSpCas9	negative selection	8767096
48969660	48969683	X	+	27260156	T47D	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.032709536268864636	[891]	[1156,973,1039,1089]	0	hSpCas9	negative selection	8824089
48969659	48969682	X	-	27260156	T47D	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.08215363764008365	[565]	[716,619,715,746]	1	hSpCas9	negative selection	8824090
48966958	48966981	X	+	27260156	T47D	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.4407593814441677	[942]	[1566,1374,1573,1455]	8	hSpCas9	negative selection	8824091
48966802	48966825	X	+	27260156	T47D	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.08520747148791608	[781]	[1150,837,924,963]	1	hSpCas9	negative selection	8888345
48967093	48967116	X	-	27260156	T47D	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.01452399941537097	[693]	[830,757,894,716]	0	hSpCas9	negative selection	8888346
48966769	48966792	X	+	27260156	T47D	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.24893792752035082	[678]	[979,761,907,1131]	5	hSpCas9	negative selection	8888347
48969660	48969683	X	+	27260156	SU8686	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	0.14959340401127597	[891]	[931,660,1212,1199]	2	hSpCas9	negative selection	8945340
48969659	48969682	X	-	27260156	SU8686	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.3910627548116547	[565]	[729,894,555,730]	6	hSpCas9	negative selection	8945341
48966958	48966981	X	+	27260156	SU8686	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.32003319725276547	[942]	[1190,929,1210,1393]	5	hSpCas9	negative selection	8945342
48966802	48966825	X	+	27260156	SU8686	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.2670478747636025	[781]	[843,771,1101,1063]	4	hSpCas9	negative selection	9009596
48967093	48967116	X	-	27260156	SU8686	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.136126873040481	[693]	[659,693,813,893]	2	hSpCas9	negative selection	9009597
48966769	48966792	X	+	27260156	SU8686	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.2794551043035287	[678]	[730,631,898,1078]	5	hSpCas9	negative selection	9009598
48969660	48969683	X	+	27260156	SKES1	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.06512772976352665	[891]	[969,766,915,756]	-1	hSpCas9	negative selection	9066591
48969659	48969682	X	-	27260156	SKES1	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	-0.04921041703686865	[565]	[656,671,456,435]	-1	hSpCas9	negative selection	9066592
48966958	48966981	X	+	27260156	SKES1	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.1512403073386388	[942]	[1184,1202,999,842]	3	hSpCas9	negative selection	9066593
48966802	48966825	X	+	27260156	SKES1	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.2869397011371482	[781]	[1029,1000,986,811]	6	hSpCas9	negative selection	9130847
48967093	48967116	X	-	27260156	SKES1	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.20389755551489763	[693]	[1063,792,871,520]	4	hSpCas9	negative selection	9130848
48966769	48966792	X	+	27260156	SKES1	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.0005913072609915471	[678]	[652,849,662,567]	0	hSpCas9	negative selection	9130849
48969660	48969683	X	+	27260156	TOV112D	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.19351108543795237	[891]	[685,819,794,822]	-4	hSpCas9	negative selection	9187842
48969659	48969682	X	-	27260156	TOV112D	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.1616435183233612	[565]	[865,578,379,713]	3	hSpCas9	negative selection	9187843
48966958	48966981	X	+	27260156	TOV112D	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.4569012588605026	[942]	[1083,1444,1195,1471]	8	hSpCas9	negative selection	9187844
48966802	48966825	X	+	27260156	TOV112D	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.17694744757116243	[781]	[888,1183,692,848]	3	hSpCas9	negative selection	9252098
48967093	48967116	X	-	27260156	TOV112D	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.44872204189867404	[693]	[523,421,559,509]	-7	hSpCas9	negative selection	9252099
48966769	48966792	X	+	27260156	TOV112D	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.410005010764771	[678]	[1016,1066,834,747]	7	hSpCas9	negative selection	9252100
48969660	48969683	X	+	27260156	TC71	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.2147184395042605	[891]	[872,721,823,878]	-5	hSpCas9	negative selection	9309093
48969659	48969682	X	-	27260156	TC71	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	-0.011638957393212357	[565]	[616,636,498,660]	0	hSpCas9	negative selection	9309094
48966958	48966981	X	+	27260156	TC71	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.32558557013804923	[942]	[1450,1251,1220,1131]	7	hSpCas9	negative selection	9309095
48966802	48966825	X	+	27260156	TC71	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.04842410878860126	[781]	[914,865,768,922]	1	hSpCas9	negative selection	9373349
48967093	48967116	X	-	27260156	TC71	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.16506098011589615	[693]	[624,732,621,676]	-4	hSpCas9	negative selection	9373350
48966769	48966792	X	+	27260156	TC71	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.08662365108674408	[678]	[803,759,658,877]	2	hSpCas9	negative selection	9373351
48969660	48969683	X	+	27260156	TC32	viability	CACATTGGCGATGACCGACACGG	KCND1	ENSG00000102057	-0.02221812926297939	[891]	[852,473,1155,966]	0	hSpCas9	negative selection	9430344
48969659	48969682	X	-	27260156	TC32	viability	CGTGTCGGTCATCGCCAATGTGG	KCND1	ENSG00000102057	0.06453742117165673	[565]	[524,491,658,559]	1	hSpCas9	negative selection	9430345
48966958	48966981	X	+	27260156	TC32	viability	GCTTGTCAGCCCGCTGGTTCTGG	KCND1	ENSG00000102057	0.39456379546268794	[942]	[1130,821,1475,1360]	7	hSpCas9	negative selection	9430346
48966802	48966825	X	+	27260156	TC32	viability	TGGTACCACTCTTTGCCAATCGG	KCND1	ENSG00000102057	0.4154280748146242	[781]	[912,664,1416,1077]	7	hSpCas9	negative selection	9494600
48967093	48967116	X	-	27260156	TC32	viability	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.10506030704960434	[693]	[708,616,761,714]	2	hSpCas9	negative selection	9494601
48966769	48966792	X	+	27260156	TC32	viability	CCCCATTCTGCTTGTACTGCAGG	KCND1	ENSG00000102057	0.3273500196989084	[678]	[714,693,925,895]	6	hSpCas9	negative selection	9494602
48962749	48962772	X	-	27869803	HPAFII	viability after 27 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.8741411954142428	[184]	[96,245,NaN]	7	hSpCas9	negative selection	9608986
48966095	48966118	X	-	27869803	HPAFII	viability after 27 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.4049076490270758	[340]	[747,246,NaN]	9	hSpCas9	negative selection	9608987
48966586	48966609	X	+	27869803	HPAFII	viability after 27 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.8099663271301257	[388]	[183,503,NaN]	6	hSpCas9	negative selection	9608988
48967093	48967116	X	-	27869803	HPAFII	viability after 27 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.8478461816622327	[420]	[621,211,NaN]	7	hSpCas9	negative selection	9608989
48969138	48969161	X	+	27869803	HPAFII	viability after 27 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	1.1757027058473162	[637]	[976,574,NaN]	8	hSpCas9	negative selection	9608990
48969917	48969940	X	+	27869803	HPAFII	viability after 27 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.9103875120700191	[352]	[212,461,NaN]	7	hSpCas9	negative selection	9608991
48962749	48962772	X	-	27869803	HPAFII	viability after 15 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.3333822747839478	[184]	[379,169,NaN]	4	hSpCas9	negative selection	9691435
48966095	48966118	X	-	27869803	HPAFII	viability after 15 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.8195783848005191	[340]	[1017,415,NaN]	8	hSpCas9	negative selection	9691436
48966586	48966609	X	+	27869803	HPAFII	viability after 15 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	-0.2173982012569679	[388]	[411,326,NaN]	-3	hSpCas9	negative selection	9691437
48967093	48967116	X	-	27869803	HPAFII	viability after 15 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.24823310829331668	[420]	[833,352,NaN]	3	hSpCas9	negative selection	9691438
48969138	48969161	X	+	27869803	HPAFII	viability after 15 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.448977822064367	[637]	[1284,718,NaN]	5	hSpCas9	negative selection	9691439
48969917	48969940	X	+	27869803	HPAFII	viability after 15 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.5007716439521486	[352]	[825,356,NaN]	6	hSpCas9	negative selection	9691440
48962749	48962772	X	-	27869803	ASPC1	viability after 36 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	1.0931938222204223	[374]	[123,426,267]	8	hSpCas9	negative selection	9773884
48966095	48966118	X	-	27869803	ASPC1	viability after 36 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.3395886219812255	[765]	[234,795,43]	3	hSpCas9	negative selection	9773885
48966586	48966609	X	+	27869803	ASPC1	viability after 36 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.05905917901630037	[870]	[179,291,428]	0	hSpCas9	negative selection	9773886
48967093	48967116	X	-	27869803	ASPC1	viability after 36 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.968735702902176	[774]	[582,510,500]	8	hSpCas9	negative selection	9773887
48969138	48969161	X	+	27869803	ASPC1	viability after 36 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.06182662844214093	[2106]	[790,1019,542]	0	hSpCas9	negative selection	9773888
48969917	48969940	X	+	27869803	ASPC1	viability after 36 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.03967689000628173	[684]	[183,101,367]	0	hSpCas9	negative selection	9773889
48962749	48962772	X	-	27869803	PATU8988S	viability after 35 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.30109072380752694	[349]	[250,95,NaN]	3	hSpCas9	negative selection	9856333
48966095	48966118	X	-	27869803	PATU8988S	viability after 35 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.9253656691967123	[617]	[560,383,NaN]	8	hSpCas9	negative selection	9856334
48966586	48966609	X	+	27869803	PATU8988S	viability after 35 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.47965760314071043	[683]	[223,544,NaN]	5	hSpCas9	negative selection	9856335
48967093	48967116	X	-	27869803	PATU8988S	viability after 35 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	-0.31456166697675975	[711]	[265,194,NaN]	-3	hSpCas9	negative selection	9856336
48969138	48969161	X	+	27869803	PATU8988S	viability after 35 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.3147429148497465	[1508]	[717,793,NaN]	3	hSpCas9	negative selection	9856337
48969917	48969940	X	+	27869803	PATU8988S	viability after 35 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.6836959343747575	[709]	[188,166,NaN]	-6	hSpCas9	negative selection	9856338
48962749	48962772	X	-	27869803	PATU8988S	viability after 31 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.3590901328406201	[349]	[189,164,NaN]	4	hSpCas9	negative selection	9938782
48966095	48966118	X	-	27869803	PATU8988S	viability after 31 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	0.7942298648456638	[617]	[502,330,NaN]	8	hSpCas9	negative selection	9938783
48966586	48966609	X	+	27869803	PATU8988S	viability after 31 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.00046080567098044645	[683]	[212,348,NaN]	0	hSpCas9	negative selection	9938784
48967093	48967116	X	-	27869803	PATU8988S	viability after 31 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	0.029198191503778392	[711]	[239,352,NaN]	0	hSpCas9	negative selection	9938785
48969138	48969161	X	+	27869803	PATU8988S	viability after 31 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	0.20376859806263137	[1508]	[615,790,NaN]	2	hSpCas9	negative selection	9938786
48969917	48969940	X	+	27869803	PATU8988S	viability after 31 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	-0.7806911740501283	[709]	[133,203,NaN]	-7	hSpCas9	negative selection	9938787
48962749	48962772	X	-	27869803	HPAFII	viability after 35 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.36238920197619034	[184]	[94,148,NaN]	2	hSpCas9	negative selection	10021231
48966095	48966118	X	-	27869803	HPAFII	viability after 35 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.4029379196736984	[340]	[519,384,NaN]	8	hSpCas9	negative selection	10021232
48966586	48966609	X	+	27869803	HPAFII	viability after 35 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.9117842448140917	[388]	[187,575,NaN]	6	hSpCas9	negative selection	10021233
48967093	48967116	X	-	27869803	HPAFII	viability after 35 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	1.4082742418225211	[420]	[766,338,NaN]	8	hSpCas9	negative selection	10021234
48969138	48969161	X	+	27869803	HPAFII	viability after 35 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	1.2448041400852834	[637]	[803,721,NaN]	8	hSpCas9	negative selection	10021235
48969917	48969940	X	+	27869803	HPAFII	viability after 35 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.3001312366021769	[352]	[164,281,NaN]	2	hSpCas9	negative selection	10021236
48962749	48962772	X	-	27869803	HPAFII	viability after 31 days	TTGACCTGAACTGCGACAGCCGG	KCND1	ENSG00000102057	0.6148726944433008	[184]	[158,158,NaN]	4	hSpCas9	negative selection	10103680
48966095	48966118	X	-	27869803	HPAFII	viability after 31 days	CCGTGGCAGCATGCAGGAGCTGG	KCND1	ENSG00000102057	1.6127757390939055	[340]	[725,431,NaN]	9	hSpCas9	negative selection	10103681
48966586	48966609	X	+	27869803	HPAFII	viability after 31 days	TCTCTAGACAGTGCAGCAAGTGG	KCND1	ENSG00000102057	0.9241027419105176	[388]	[229,614,NaN]	7	hSpCas9	negative selection	10103682
48967093	48967116	X	-	27869803	HPAFII	viability after 31 days	TCGCTCCAGCTACGGAGACATGG	KCND1	ENSG00000102057	1.1450214478783736	[420]	[801,217,NaN]	8	hSpCas9	negative selection	10103683
48969138	48969161	X	+	27869803	HPAFII	viability after 31 days	AGTCCACACTCACCCAAGCGTGG	KCND1	ENSG00000102057	1.2510310113791518	[637]	[923,773,NaN]	8	hSpCas9	negative selection	10103684
48969917	48969940	X	+	27869803	HPAFII	viability after 31 days	CCAGCTCTTCGTCGAAGGCCTGG	KCND1	ENSG00000102057	0.2581986944505744	[352]	[134,347,NaN]	1	hSpCas9	negative selection	10103685
48969371	48969394	X	+	28162770	P31FUJ	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.17600334115295047	[115]	[153]	1	hSpCas9	negative selection	10177503
48970097	48970120	X	-	28162770	P31FUJ	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	0.01587690844234535	[100]	[119]	0	hSpCas9	negative selection	10177504
48966968	48966991	X	-	28162770	P31FUJ	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.45027038175662554	[179]	[288]	5	hSpCas9	negative selection	10177505
48969966	48969989	X	-	28162770	P31FUJ	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.49881015525762085	[161]	[268]	5	hSpCas9	negative selection	10177506
48969848	48969871	X	-	28162770	P31FUJ	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.4501354558700752	[184]	[296]	5	hSpCas9	negative selection	10177507
48969815	48969838	X	-	28162770	P31FUJ	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-0.6113138276681085	[103]	[79]	-5	hSpCas9	negative selection	10177508
48969796	48969819	X	-	28162770	P31FUJ	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-1.3293754641094315	[138]	[64]	-7	hSpCas9	negative selection	10177509
48969637	48969660	X	-	28162770	P31FUJ	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.7498157173573851	[166]	[329]	8	hSpCas9	negative selection	10177510
48970188	48970211	X	+	28162770	P31FUJ	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	0.02419159926211556	[358]	[428]	0	hSpCas9	negative selection	10177511
48970151	48970174	X	-	28162770	P31FUJ	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.14046776362753832	[402]	[521]	1	hSpCas9	negative selection	10177512
48969371	48969394	X	+	28162770	TF1	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10346869
48970097	48970120	X	-	28162770	TF1	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	NaN	[NaN]	[152]	1	hSpCas9	negative selection	10346870
48966968	48966991	X	-	28162770	TF1	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	NaN	[NaN]	[162]	1	hSpCas9	negative selection	10346871
48969966	48969989	X	-	28162770	TF1	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10346872
48969848	48969871	X	-	28162770	TF1	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10346873
48969815	48969838	X	-	28162770	TF1	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10346874
48969796	48969819	X	-	28162770	TF1	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	NaN	[NaN]	[81]	1	hSpCas9	negative selection	10346875
48969637	48969660	X	-	28162770	TF1	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10346876
48970188	48970211	X	+	28162770	TF1	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10346877
48970151	48970174	X	-	28162770	TF1	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	NaN	[NaN]	[487]	1	hSpCas9	negative selection	10346878
48969371	48969394	X	+	28162770	SKM1	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.2127637201386712	[40]	[83]	2	hSpCas9	negative selection	10516235
48970097	48970120	X	-	28162770	SKM1	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	-0.11150831521699045	[21]	[35]	-1	hSpCas9	negative selection	10516236
48966968	48966991	X	-	28162770	SKM1	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	-1.0335058032157172	[65]	[56]	-6	hSpCas9	negative selection	10516237
48969966	48969989	X	-	28162770	SKM1	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-1.440131062678361	[65]	[42]	-7	hSpCas9	negative selection	10516238
48969848	48969871	X	-	28162770	SKM1	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.17799830197799443	[62]	[125]	1	hSpCas9	negative selection	10516239
48969815	48969838	X	-	28162770	SKM1	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.14147242595288034	[19]	[38]	1	hSpCas9	negative selection	10516240
48969796	48969819	X	-	28162770	SKM1	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	1.393011192948845	[13]	[64]	9	hSpCas9	negative selection	10516241
48969637	48969660	X	-	28162770	SKM1	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.34792330342030686	[43]	[98]	3	hSpCas9	negative selection	10516242
48970188	48970211	X	+	28162770	SKM1	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.6520766965796931	[79]	[89]	-5	hSpCas9	negative selection	10516243
48970151	48970174	X	-	28162770	SKM1	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.3664433913911047	[85]	[195]	3	hSpCas9	negative selection	10516244
48969371	48969394	X	+	28162770	SKM1	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.2127637201386712	[40]	[83]	2	hSpCas9	negative selection	10685601
48970097	48970120	X	-	28162770	SKM1	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	-0.11150831521699045	[21]	[35]	-1	hSpCas9	negative selection	10685602
48966968	48966991	X	-	28162770	SKM1	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	-1.0335058032157172	[65]	[56]	-6	hSpCas9	negative selection	10685603
48969966	48969989	X	-	28162770	SKM1	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-1.440131062678361	[65]	[42]	-7	hSpCas9	negative selection	10685604
48969848	48969871	X	-	28162770	SKM1	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.17799830197799443	[62]	[125]	1	hSpCas9	negative selection	10685605
48969815	48969838	X	-	28162770	SKM1	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.14147242595288034	[19]	[38]	1	hSpCas9	negative selection	10685606
48969796	48969819	X	-	28162770	SKM1	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	1.393011192948845	[13]	[64]	9	hSpCas9	negative selection	10685607
48969637	48969660	X	-	28162770	SKM1	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.34792330342030686	[43]	[98]	3	hSpCas9	negative selection	10685608
48970188	48970211	X	+	28162770	SKM1	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.6520766965796931	[79]	[89]	-5	hSpCas9	negative selection	10685609
48970151	48970174	X	-	28162770	SKM1	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.3664433913911047	[85]	[195]	3	hSpCas9	negative selection	10685610
48969371	48969394	X	+	28162770	PL21	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.08910830210057638	[161]	[74]	0	hSpCas9	negative selection	10854967
48970097	48970120	X	-	28162770	PL21	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	-0.23426320965645475	[99]	[36]	-2	hSpCas9	negative selection	10854968
48966968	48966991	X	-	28162770	PL21	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	1.0374101144512118	[149]	[133]	8	hSpCas9	negative selection	10854969
48969966	48969989	X	-	28162770	PL21	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	1.5480629179096272	[153]	[195]	9	hSpCas9	negative selection	10854970
48969848	48969871	X	-	28162770	PL21	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.20013961448932016	[279]	[139]	1	hSpCas9	negative selection	10854971
48969815	48969838	X	-	28162770	PL21	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.516167107936998	[97]	[60]	4	hSpCas9	negative selection	10854972
48969796	48969819	X	-	28162770	PL21	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-0.49017588637806453	[70]	[21]	-3	hSpCas9	negative selection	10854973
48969637	48969660	X	-	28162770	PL21	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	-0.184524235746005	[187]	[71]	-1	hSpCas9	negative selection	10854974
48970188	48970211	X	+	28162770	PL21	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.43570405523401995	[201]	[64]	-3	hSpCas9	negative selection	10854975
48970151	48970174	X	-	28162770	PL21	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.7708882559907755	[271]	[201]	6	hSpCas9	negative selection	10854976
48969371	48969394	X	+	28162770	P31FUJ	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.17600334115295047	[115]	[153]	1	hSpCas9	negative selection	11024333
48970097	48970120	X	-	28162770	P31FUJ	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	0.01587690844234535	[100]	[119]	0	hSpCas9	negative selection	11024334
48966968	48966991	X	-	28162770	P31FUJ	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.45027038175662554	[179]	[288]	5	hSpCas9	negative selection	11024335
48969966	48969989	X	-	28162770	P31FUJ	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.49881015525762085	[161]	[268]	5	hSpCas9	negative selection	11024336
48969848	48969871	X	-	28162770	P31FUJ	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.4501354558700752	[184]	[296]	5	hSpCas9	negative selection	11024337
48969815	48969838	X	-	28162770	P31FUJ	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-0.6113138276681085	[103]	[79]	-5	hSpCas9	negative selection	11024338
48969796	48969819	X	-	28162770	P31FUJ	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-1.3293754641094315	[138]	[64]	-7	hSpCas9	negative selection	11024339
48969637	48969660	X	-	28162770	P31FUJ	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.7498157173573851	[166]	[329]	8	hSpCas9	negative selection	11024340
48970188	48970211	X	+	28162770	P31FUJ	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	0.02419159926211556	[358]	[428]	0	hSpCas9	negative selection	11024341
48970151	48970174	X	-	28162770	P31FUJ	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.14046776362753832	[402]	[521]	1	hSpCas9	negative selection	11024342
48969371	48969394	X	+	28162770	OCIAML5	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.9339935728303788	[77]	[268]	7	hSpCas9	negative selection	11193699
48970097	48970120	X	-	28162770	OCIAML5	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	-0.07628172780726261	[65]	[112]	0	hSpCas9	negative selection	11193700
48966968	48966991	X	-	28162770	OCIAML5	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	1.437030131555993	[79]	[390]	9	hSpCas9	negative selection	11193701
48969966	48969989	X	-	28162770	OCIAML5	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.935629825423139	[94]	[327]	7	hSpCas9	negative selection	11193702
48969848	48969871	X	-	28162770	OCIAML5	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.6279263702556167	[94]	[264]	5	hSpCas9	negative selection	11193703
48969815	48969838	X	-	28162770	OCIAML5	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.13105961057160687	[42]	[84]	1	hSpCas9	negative selection	11193704
48969796	48969819	X	-	28162770	OCIAML5	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-0.3995543661664902	[56]	[77]	-3	hSpCas9	negative selection	11193705
48969637	48969660	X	-	28162770	OCIAML5	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.2695628735375341	[107]	[234]	2	hSpCas9	negative selection	11193706
48970188	48970211	X	+	28162770	OCIAML5	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	0.2761591392979271	[155]	[340]	2	hSpCas9	negative selection	11193707
48970151	48970174	X	-	28162770	OCIAML5	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.41096783496979694	[179]	[431]	3	hSpCas9	negative selection	11193708
48969371	48969394	X	+	28162770	EOL1	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	1.6280547240594427	[252]	[411]	9	hSpCas9	negative selection	11363065
48970097	48970120	X	-	28162770	EOL1	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	0.8176325676540225	[111]	[103]	7	hSpCas9	negative selection	11363066
48966968	48966991	X	-	28162770	EOL1	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.08088980073992194	[331]	[184]	0	hSpCas9	negative selection	11363067
48969966	48969989	X	-	28162770	EOL1	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.11244643591166702	[315]	[153]	-1	hSpCas9	negative selection	11363068
48969848	48969871	X	-	28162770	EOL1	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.07161615935600352	[409]	[226]	0	hSpCas9	negative selection	11363069
48969815	48969838	X	-	28162770	EOL1	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.24073188392309308	[150]	[93]	2	hSpCas9	negative selection	11363070
48969796	48969819	X	-	28162770	EOL1	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-0.6170221336372408	[130]	[44]	-4	hSpCas9	negative selection	11363071
48969637	48969660	X	-	28162770	EOL1	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.251712514824044	[219]	[137]	2	hSpCas9	negative selection	11363072
48970188	48970211	X	+	28162770	EOL1	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.2296528775787614	[364]	[163]	-2	hSpCas9	negative selection	11363073
48970151	48970174	X	-	28162770	EOL1	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.014745580542112724	[371]	[197]	0	hSpCas9	negative selection	11363074
48969371	48969394	X	+	28162770	MOLM13	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.14008472032054708	[245]	[195]	1	hSpCas9	negative selection	11532431
48970097	48970120	X	-	28162770	MOLM13	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	-1.1960614153234062	[243]	[76]	-6	hSpCas9	negative selection	11532432
48966968	48966991	X	-	28162770	MOLM13	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.9178867191772228	[264]	[361]	7	hSpCas9	negative selection	11532433
48969966	48969989	X	-	28162770	MOLM13	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.8651240583036696	[264]	[348]	6	hSpCas9	negative selection	11532434
48969848	48969871	X	-	28162770	MOLM13	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.4213467956075486	[314]	[304]	3	hSpCas9	negative selection	11532435
48969815	48969838	X	-	28162770	MOLM13	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-0.13697267661428225	[72]	[47]	-1	hSpCas9	negative selection	11532436
48969796	48969819	X	-	28162770	MOLM13	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-1.7227941800645308	[104]	[22]	-7	hSpCas9	negative selection	11532437
48969637	48969660	X	-	28162770	MOLM13	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	-1.1395279700042733	[258]	[84]	-5	hSpCas9	negative selection	11532438
48970188	48970211	X	+	28162770	MOLM13	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	0.012617957463059312	[302]	[220]	0	hSpCas9	negative selection	11532439
48970151	48970174	X	-	28162770	MOLM13	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.5139017793014147	[431]	[445]	4	hSpCas9	negative selection	11532440
48969371	48969394	X	+	28162770	HEL	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.2162603921847989	[210]	[156]	1	hSpCas9	negative selection	11701797
48970097	48970120	X	-	28162770	HEL	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	0.45870688436266904	[166]	[146]	4	hSpCas9	negative selection	11701798
48966968	48966991	X	-	28162770	HEL	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	1.2744077142332477	[232]	[360]	9	hSpCas9	negative selection	11701799
48969966	48969989	X	-	28162770	HEL	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.3305697035753233	[220]	[177]	2	hSpCas9	negative selection	11701800
48969848	48969871	X	-	28162770	HEL	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.9164996444272092	[267]	[323]	7	hSpCas9	negative selection	11701801
48969815	48969838	X	-	28162770	HEL	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	2.003141074702355	[73]	[189]	9	hSpCas9	negative selection	11701802
48969796	48969819	X	-	28162770	HEL	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-1.0117646019738762	[84]	[26]	-6	hSpCas9	negative selection	11701803
48969637	48969660	X	-	28162770	HEL	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	-0.4384572508476238	[200]	[94]	-3	hSpCas9	negative selection	11701804
48970188	48970211	X	+	28162770	HEL	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	0.16042237982049848	[277]	[198]	1	hSpCas9	negative selection	11701805
48970151	48970174	X	-	28162770	HEL	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.6381073832687111	[311]	[310]	5	hSpCas9	negative selection	11701806
48969371	48969394	X	+	28162770	MV411	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.9909459908157534	[131]	[220]	8	hSpCas9	negative selection	11871163
48970097	48970120	X	-	28162770	MV411	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	1.0045810268866118	[70]	[119]	8	hSpCas9	negative selection	11871164
48966968	48966991	X	-	28162770	MV411	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.8383248854610368	[161]	[243]	7	hSpCas9	negative selection	11871165
48969966	48969989	X	-	28162770	MV411	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	1.4535740813613036	[152]	[352]	9	hSpCas9	negative selection	11871166
48969848	48969871	X	-	28162770	MV411	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.21600504294611816	[231]	[226]	1	hSpCas9	negative selection	11871167
48969815	48969838	X	-	28162770	MV411	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.7155863865211817	[59]	[82]	6	hSpCas9	negative selection	11871168
48969796	48969819	X	-	28162770	MV411	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-2.0354964124887234	[72]	[14]	-8	hSpCas9	negative selection	11871169
48969637	48969660	X	-	28162770	MV411	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	1.392635466322711	[169]	[375]	9	hSpCas9	negative selection	11871170
48970188	48970211	X	+	28162770	MV411	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.8456718536087062	[255]	[119]	-5	hSpCas9	negative selection	11871171
48970151	48970174	X	-	28162770	MV411	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	1.1436017397982352	[179]	[334]	8	hSpCas9	negative selection	11871172
48969371	48969394	X	+	28162770	MONOMAC1	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	0.8964750388635907	[111]	[238]	8	hSpCas9	negative selection	12040529
48970097	48970120	X	-	28162770	MONOMAC1	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	1.0974105114057016	[52]	[129]	8	hSpCas9	negative selection	12040530
48966968	48966991	X	-	28162770	MONOMAC1	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	1.289278065728691	[115]	[324]	9	hSpCas9	negative selection	12040531
48969966	48969989	X	-	28162770	MONOMAC1	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.7249606409391731	[113]	[215]	7	hSpCas9	negative selection	12040532
48969848	48969871	X	-	28162770	MONOMAC1	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.7806644858316718	[162]	[320]	7	hSpCas9	negative selection	12040533
48969815	48969838	X	-	28162770	MONOMAC1	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-0.22303205559249806	[55]	[54]	-2	hSpCas9	negative selection	12040534
48969796	48969819	X	-	28162770	MONOMAC1	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-1.2811011118480282	[52]	[24]	-7	hSpCas9	negative selection	12040535
48969637	48969660	X	-	28162770	MONOMAC1	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.4600754394174379	[77]	[122]	4	hSpCas9	negative selection	12040536
48970188	48970211	X	+	28162770	MONOMAC1	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.06928129986118114	[161]	[176]	0	hSpCas9	negative selection	12040537
48970151	48970174	X	-	28162770	MONOMAC1	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.06367250582799644	[206]	[247]	0	hSpCas9	negative selection	12040538
48969371	48969394	X	+	28162770	OCIAML2	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	-1.243858963395139	[46]	[109]	-7	hSpCas9	negative selection	12209895
48970097	48970120	X	-	28162770	OCIAML2	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	1.5935005121775543	[10]	[183]	9	hSpCas9	negative selection	12209896
48966968	48966991	X	-	28162770	OCIAML2	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.951902210583607	[35]	[385]	8	hSpCas9	negative selection	12209897
48969966	48969989	X	-	28162770	OCIAML2	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	-0.28620525410473374	[32]	[149]	-2	hSpCas9	negative selection	12209898
48969848	48969871	X	-	28162770	OCIAML2	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.7220152527002345	[55]	[511]	7	hSpCas9	negative selection	12209899
48969815	48969838	X	-	28162770	OCIAML2	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	0.7144815800148273	[20]	[190]	7	hSpCas9	negative selection	12209900
48969796	48969819	X	-	28162770	OCIAML2	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-0.41618204121978497	[12]	[53]	-3	hSpCas9	negative selection	12209901
48969637	48969660	X	-	28162770	OCIAML2	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	0.13670048850744948	[31]	[194]	1	hSpCas9	negative selection	12209902
48970188	48970211	X	+	28162770	OCIAML2	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.08235923552610294	[33]	[177]	0	hSpCas9	negative selection	12209903
48970151	48970174	X	-	28162770	OCIAML2	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.8776324174586637	[37]	[386]	8	hSpCas9	negative selection	12209904
48969371	48969394	X	+	28162770	OCIAML3	viability	GAAACACCCGGAACACACGCAGG	KCND1	ENSG00000102057	-0.29361270698644204	[53]	[132]	-2	hSpCas9	negative selection	12379261
48970097	48970120	X	-	28162770	OCIAML3	viability	TGAGACTTGGAAGAATACGCTGG	KCND1	ENSG00000102057	0.21334728173344097	[13]	[48]	2	hSpCas9	negative selection	12379262
48966968	48966991	X	-	28162770	OCIAML3	viability	GCATCTACCACCAGAACCAGCGG	KCND1	ENSG00000102057	0.4934552009261761	[47]	[203]	4	hSpCas9	negative selection	12379263
48969966	48969989	X	-	28162770	OCIAML3	viability	TGAACTTCTACCGAACGGGGCGG	KCND1	ENSG00000102057	0.296204214137725	[57]	[214]	2	hSpCas9	negative selection	12379264
48969848	48969871	X	-	28162770	OCIAML3	viability	AGAGTATCGGGACCGAAAGAAGG	KCND1	ENSG00000102057	0.4706453180180904	[59]	[250]	4	hSpCas9	negative selection	12379265
48969815	48969838	X	-	28162770	OCIAML3	viability	GCGCCTGGCAGAGGATGAGGAGG	KCND1	ENSG00000102057	-1.5467019255458065	[29]	[30]	-8	hSpCas9	negative selection	12379266
48969796	48969819	X	-	28162770	OCIAML3	viability	GAGGCAGAGCAGGCCGGGGACGG	KCND1	ENSG00000102057	-2.382503535130451	[18]	[10]	-9	hSpCas9	negative selection	12379267
48969637	48969660	X	-	28162770	OCIAML3	viability	GTGGAGACCATCCCATGCCGCGG	KCND1	ENSG00000102057	-1.0251648049662838	[59]	[88]	-6	hSpCas9	negative selection	12379268
48970188	48970211	X	+	28162770	OCIAML3	viability	GGGCAGGGGTTGCTGGGCCAGGG	KCND1	ENSG00000102057	-0.4261659533823397	[76]	[172]	-3	hSpCas9	negative selection	12379269
48970151	48970174	X	-	28162770	OCIAML3	viability	GAAGGCATCTCGAGGAGATGAGG	KCND1	ENSG00000102057	0.722195466729569	[100]	[502]	6	hSpCas9	negative selection	12379270