Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3787
• Symbol:KCNS1
• Description:potassium voltage-gated channel modifier subfamily S member 1

DataSource: http://genomecrispr.dkfz.de/#!/results/KCNS1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
45099176	45099199	20	+	26472758	Jiyoye	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.1388075313690389	[270]	[224]	1	hSpCas9	negative selection	81683
45098480	45098503	20	-	26472758	Jiyoye	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.9538097635679301	[88]	[129]	6	hSpCas9	negative selection	81684
45098602	45098625	20	-	26472758	Jiyoye	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	0.3914080656475568	[91]	[90]	3	hSpCas9	negative selection	81685
45098429	45098452	20	+	26472758	Jiyoye	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-0.10378653777150602	[113]	[79]	0	hSpCas9	negative selection	81686
45098052	45098075	20	+	26472758	Jiyoye	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	1.3825133272716044	[58]	[115]	8	hSpCas9	negative selection	81687
45098021	45098044	20	-	26472758	Jiyoye	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.8173634811233215	[148]	[197]	6	hSpCas9	negative selection	81688
45097780	45097803	20	-	26472758	Jiyoye	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	0.6229040725613106	[30]	[35]	4	hSpCas9	negative selection	81689
45097650	45097673	20	+	26472758	Jiyoye	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-0.07825144566436837	[41]	[29]	0	hSpCas9	negative selection	81690
45099160	45099183	20	-	26472758	Jiyoye	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.7666540743923551	[184]	[81]	-5	hSpCas9	negative selection	81691
45098589	45098612	20	-	26472758	Jiyoye	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	0.4713057189255889	[21]	[22]	3	hSpCas9	negative selection	81692
45099176	45099199	20	+	26472758	KBM7	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.6986562411456293	[1024,678]	[812,484]	7	hSpCas9	negative selection	272801
45098480	45098503	20	-	26472758	KBM7	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.6353778371726373	[645,682]	[534,447]	7	hSpCas9	negative selection	272802
45098602	45098625	20	-	26472758	KBM7	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-0.048316629252804166	[465,316]	[176,173]	0	hSpCas9	negative selection	272803
45098429	45098452	20	+	26472758	KBM7	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	0.0983912523960587	[617,293]	[357,100]	1	hSpCas9	negative selection	272804
45098052	45098075	20	+	26472758	KBM7	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.1366970252228331	[360,248]	[174,137]	1	hSpCas9	negative selection	272805
45098021	45098044	20	-	26472758	KBM7	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.12061307315997677	[661,487]	[350,236]	1	hSpCas9	negative selection	272806
45097780	45097803	20	-	26472758	KBM7	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-0.14030451851999404	[246,223]	[72,124]	-1	hSpCas9	negative selection	272807
45097650	45097673	20	+	26472758	KBM7	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-0.6270675630368157	[247,135]	[75,39]	-5	hSpCas9	negative selection	272808
45099160	45099183	20	-	26472758	KBM7	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.3414292390830276	[480,562]	[286,339]	3	hSpCas9	negative selection	272809
45098589	45098612	20	-	26472758	KBM7	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	0.48679177909507176	[32,20]	[17,16]	5	hSpCas9	negative selection	272810
45099176	45099199	20	+	26472758	Raji	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.25442464614257343	[465]	[128]	2	hSpCas9	negative selection	463919
45098480	45098503	20	-	26472758	Raji	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.1287571861661665	[267]	[67]	1	hSpCas9	negative selection	463920
45098602	45098625	20	-	26472758	Raji	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-0.6768877735709633	[185]	[26]	-5	hSpCas9	negative selection	463921
45098429	45098452	20	+	26472758	Raji	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	0.4456638356684053	[192]	[60]	4	hSpCas9	negative selection	463922
45098052	45098075	20	+	26472758	Raji	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.619445489047308	[114]	[40]	6	hSpCas9	negative selection	463923
45098021	45098044	20	-	26472758	Raji	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.18159413771247618	[302]	[61]	-1	hSpCas9	negative selection	463924
45097780	45097803	20	-	26472758	Raji	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	0.05153030064008224	[78]	[18]	0	hSpCas9	negative selection	463925
45097650	45097673	20	+	26472758	Raji	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-0.24311371171053375	[50]	[9]	-2	hSpCas9	negative selection	463926
45099160	45099183	20	-	26472758	Raji	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.37342173405626466	[373]	[66]	-3	hSpCas9	negative selection	463927
45098589	45098612	20	-	26472758	Raji	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	463928
45099176	45099199	20	+	26472758	K562	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.31785417426945717	[765]	[805]	2	hSpCas9	negative selection	655037
45098480	45098503	20	-	26472758	K562	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.6574285455983082	[533]	[710]	5	hSpCas9	negative selection	655038
45098602	45098625	20	-	26472758	K562	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	0.36629073119546196	[328]	[357]	3	hSpCas9	negative selection	655039
45098429	45098452	20	+	26472758	K562	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-1.8226954681920904	[263]	[62]	-7	hSpCas9	negative selection	655040
45098052	45098075	20	+	26472758	K562	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	1.1080972564536669	[182]	[332]	8	hSpCas9	negative selection	655041
45098021	45098044	20	-	26472758	K562	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.427785992020832	[545]	[619]	3	hSpCas9	negative selection	655042
45097780	45097803	20	-	26472758	K562	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-0.8455626391712189	[214]	[100]	-5	hSpCas9	negative selection	655043
45097650	45097673	20	+	26472758	K562	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-0.252412862776044	[126]	[89]	-2	hSpCas9	negative selection	655044
45099160	45099183	20	-	26472758	K562	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.04350603374045049	[399]	[347]	0	hSpCas9	negative selection	655045
45098589	45098612	20	-	26472758	K562	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.3613023332215066	[34]	[22]	-2	hSpCas9	negative selection	655046
45095011	45095034	20	+	26627737	DLD1	viability	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.15058200181024017	[1295]	[495,552,323]	1	hSpCas9	negative selection	814729
45095046	45095069	20	+	26627737	DLD1	viability	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.5348920496496894	[334]	[118,181,154]	5	hSpCas9	negative selection	814730
45095046	45095069	20	-	26627737	DLD1	viability	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.4657469715890717	[247]	[131,138,58]	5	hSpCas9	negative selection	814731
45097844	45097867	20	+	26627737	DLD1	viability	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.8605978562594925	[1033]	[336,106,98]	-7	hSpCas9	negative selection	814732
45098410	45098433	20	-	26627737	DLD1	viability	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.801751230955495	[2361]	[408,558,323]	-6	hSpCas9	negative selection	814733
45098658	45098681	20	+	26627737	DLD1	viability	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.010371341861319161	[962]	[298,366,253]	0	hSpCas9	negative selection	814734
45095011	45095034	20	+	26627737	GBM cells	viability after 5 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.4901489726223718	[305]	[298,161]	7	hSpCas9	negative selection	897044
45095046	45095069	20	+	26627737	GBM cells	viability after 5 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.42616087775055445	[305]	[216,223]	6	hSpCas9	negative selection	897045
45095046	45095069	20	-	26627737	GBM cells	viability after 5 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.24286827610304676	[207]	[148,114]	4	hSpCas9	negative selection	897046
45097844	45097867	20	+	26627737	GBM cells	viability after 5 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.5049088368972316	[298]	[71,153]	-7	hSpCas9	negative selection	897047
45098410	45098433	20	-	26627737	GBM cells	viability after 5 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.1444595344499704	[573]	[294,261]	-2	hSpCas9	negative selection	897048
45098658	45098681	20	+	26627737	GBM cells	viability after 5 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.28903374196019993	[437]	[318,254]	4	hSpCas9	negative selection	897049
45095011	45095034	20	+	26627737	GBM cells	viability after 13 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.32632752814460897	[305]	[200,213]	4	hSpCas9	negative selection	979359
45095046	45095069	20	+	26627737	GBM cells	viability after 13 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.3330891805691051	[305]	[228,192]	4	hSpCas9	negative selection	979360
45095046	45095069	20	-	26627737	GBM cells	viability after 13 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.33789522850840276	[207]	[183,108]	4	hSpCas9	negative selection	979361
45097844	45097867	20	+	26627737	GBM cells	viability after 13 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.5341648193066567	[298]	[100,120]	-6	hSpCas9	negative selection	979362
45098410	45098433	20	-	26627737	GBM cells	viability after 13 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.653232894856689	[573]	[186,206]	-6	hSpCas9	negative selection	979363
45098658	45098681	20	+	26627737	GBM cells	viability after 13 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.011524979011067749	[437]	[232,237]	0	hSpCas9	negative selection	979364
45095011	45095034	20	+	26627737	GBM cells	viability after 21 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.8566248917295902	[305]	[311,290]	8	hSpCas9	negative selection	1061674
45095046	45095069	20	+	26627737	GBM cells	viability after 21 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.1658772771782443	[305]	[209,164]	1	hSpCas9	negative selection	1061675
45095046	45095069	20	-	26627737	GBM cells	viability after 21 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.7499022719991091	[207]	[200,179]	7	hSpCas9	negative selection	1061676
45097844	45097867	20	+	26627737	GBM cells	viability after 21 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.7100465619414351	[298]	[103,94]	-6	hSpCas9	negative selection	1061677
45098410	45098433	20	-	26627737	GBM cells	viability after 21 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.41109280507417345	[573]	[233,234]	-4	hSpCas9	negative selection	1061678
45098658	45098681	20	+	26627737	GBM cells	viability after 21 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.23964435791907202	[437]	[281,279]	2	hSpCas9	negative selection	1061679
45095011	45095034	20	+	26627737	RPE1	viability after 9 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	-0.06577067159461825	[2030]	[393,882]	0	hSpCas9	negative selection	1143989
45095046	45095069	20	+	26627737	RPE1	viability after 9 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.7432732908584253	[564]	[344,232]	5	hSpCas9	negative selection	1143990
45095046	45095069	20	-	26627737	RPE1	viability after 9 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.342706383368224	[547]	[124,336]	2	hSpCas9	negative selection	1143991
45097844	45097867	20	+	26627737	RPE1	viability after 9 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-1.1003550087963097	[1843]	[270,266]	-7	hSpCas9	negative selection	1143992
45098410	45098433	20	-	26627737	RPE1	viability after 9 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.03892271654894919	[1643]	[440,641]	0	hSpCas9	negative selection	1143993
45098658	45098681	20	+	26627737	RPE1	viability after 9 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.8866338137100152	[3419]	[355,866]	-6	hSpCas9	negative selection	1143994
45095011	45095034	20	+	26627737	RPE1	viability after 12 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.012099044933591596	[2030]	[422,684]	0	hSpCas9	negative selection	1226304
45095046	45095069	20	+	26627737	RPE1	viability after 12 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.7621928407775813	[564]	[221,294]	5	hSpCas9	negative selection	1226305
45095046	45095069	20	-	26627737	RPE1	viability after 12 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.898215999998061	[547]	[253,295]	5	hSpCas9	negative selection	1226306
45097844	45097867	20	+	26627737	RPE1	viability after 12 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-1.4249228200871857	[1843]	[167,201]	-7	hSpCas9	negative selection	1226307
45098410	45098433	20	-	26627737	RPE1	viability after 12 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.29102814512137387	[1643]	[326,396]	-2	hSpCas9	negative selection	1226308
45098658	45098681	20	+	26627737	RPE1	viability after 12 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-1.3956414133554516	[3419]	[322,376]	-7	hSpCas9	negative selection	1226309
45095011	45095034	20	+	26627737	RPE1	viability after 15 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.05459036656934435	[2030]	[473,714]	0	hSpCas9	negative selection	1308619
45095046	45095069	20	+	26627737	RPE1	viability after 15 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.9675630780159826	[564]	[309,314]	6	hSpCas9	negative selection	1308620
45095046	45095069	20	-	26627737	RPE1	viability after 15 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.20838934583228552	[547]	[144,211]	1	hSpCas9	negative selection	1308621
45097844	45097867	20	+	26627737	RPE1	viability after 15 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-1.392350442644627	[1843]	[214,182]	-7	hSpCas9	negative selection	1308622
45098410	45098433	20	-	26627737	RPE1	viability after 15 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.6803152411280262	[1643]	[1012,486]	4	hSpCas9	negative selection	1308623
45098658	45098681	20	+	26627737	RPE1	viability after 15 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.5588884063470796	[3419]	[615,695]	-4	hSpCas9	negative selection	1308624
45095011	45095034	20	+	26627737	RPE1	viability after 18 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.29276930742971197	[2030]	[639,704]	1	hSpCas9	negative selection	1390934
45095046	45095069	20	+	26627737	RPE1	viability after 18 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.6067205815907949	[564]	[193,272]	4	hSpCas9	negative selection	1390935
45095046	45095069	20	-	26627737	RPE1	viability after 18 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.7432385553074148	[547]	[219,276]	4	hSpCas9	negative selection	1390936
45097844	45097867	20	+	26627737	RPE1	viability after 18 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.7443363096758377	[1843]	[327,263]	-5	hSpCas9	negative selection	1390937
45098410	45098433	20	-	26627737	RPE1	viability after 18 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.21514593342163324	[1643]	[285,484]	-1	hSpCas9	negative selection	1390938
45098658	45098681	20	+	26627737	RPE1	viability after 18 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.8580398540648981	[3419]	[339,689]	-5	hSpCas9	negative selection	1390939
45095011	45095034	20	+	26627737	HeLa	viability after 8 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	-0.0839643236588522	[599]	[291,254,204]	-1	hSpCas9	negative selection	1473249
45095046	45095069	20	+	26627737	HeLa	viability after 8 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.2677259083465988	[444]	[342,94,281]	2	hSpCas9	negative selection	1473250
45095046	45095069	20	-	26627737	HeLa	viability after 8 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.3046964522730006	[256]	[190,66,165]	3	hSpCas9	negative selection	1473251
45097844	45097867	20	+	26627737	HeLa	viability after 8 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.48391477619778767	[601]	[229,267,80]	-5	hSpCas9	negative selection	1473252
45098410	45098433	20	-	26627737	HeLa	viability after 8 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.4628505679177767	[677]	[384,436,393]	4	hSpCas9	negative selection	1473253
45098658	45098681	20	+	26627737	HeLa	viability after 8 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.18114432921400137	[942]	[383,320,383]	-2	hSpCas9	negative selection	1473254
45095011	45095034	20	+	26627737	HeLa	viability after 12 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.042021566991206405	[599]	[352,176,246]	0	hSpCas9	negative selection	1555564
45095046	45095069	20	+	26627737	HeLa	viability after 12 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	-0.594725456411028	[444]	[122,77,168]	-5	hSpCas9	negative selection	1555565
45095046	45095069	20	-	26627737	HeLa	viability after 12 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.8205172895866168	[256]	[428,33,122]	6	hSpCas9	negative selection	1555566
45097844	45097867	20	+	26627737	HeLa	viability after 12 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.4342220038641683	[601]	[178,223,144]	-4	hSpCas9	negative selection	1555567
45098410	45098433	20	-	26627737	HeLa	viability after 12 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.33881006960447824	[677]	[129,277,247]	-3	hSpCas9	negative selection	1555568
45098658	45098681	20	+	26627737	HeLa	viability after 12 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.41385448713683604	[942]	[246,341,281]	-4	hSpCas9	negative selection	1555569
45095011	45095034	20	+	26627737	HeLa	viability after 15 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.0532685569652549	[599]	[135,249,385]	0	hSpCas9	negative selection	1637879
45095046	45095069	20	+	26627737	HeLa	viability after 15 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	-0.3507767552520268	[444]	[186,139,94]	-3	hSpCas9	negative selection	1637880
45095046	45095069	20	-	26627737	HeLa	viability after 15 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	-0.3235009404706388	[256]	[93,8,152]	-3	hSpCas9	negative selection	1637881
45097844	45097867	20	+	26627737	HeLa	viability after 15 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.7891466944626799	[601]	[70,193,162]	-6	hSpCas9	negative selection	1637882
45098410	45098433	20	-	26627737	HeLa	viability after 15 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.5500798055071315	[677]	[489,368,347]	4	hSpCas9	negative selection	1637883
45098658	45098681	20	+	26627737	HeLa	viability after 15 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.31484612791694855	[942]	[351,316,251]	-3	hSpCas9	negative selection	1637884
45095011	45095034	20	+	26627737	HeLa	viability after 18 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.06301924547259741	[599]	[84,218,385]	0	hSpCas9	negative selection	1720194
45095046	45095069	20	+	26627737	HeLa	viability after 18 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	-0.3055983993435715	[444]	[126,124,94]	-3	hSpCas9	negative selection	1720195
45095046	45095069	20	-	26627737	HeLa	viability after 18 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	-0.31318340184610394	[256]	[62,8,152]	-3	hSpCas9	negative selection	1720196
45097844	45097867	20	+	26627737	HeLa	viability after 18 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.8004254355990886	[601]	[49,154,162]	-6	hSpCas9	negative selection	1720197
45098410	45098433	20	-	26627737	HeLa	viability after 18 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.5632201785355234	[677]	[333,307,347]	4	hSpCas9	negative selection	1720198
45098658	45098681	20	+	26627737	HeLa	viability after 18 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.3365600279098053	[942]	[225,263,251]	-3	hSpCas9	negative selection	1720199
45095011	45095034	20	+	26627737	HCT116	viability after 6 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.16363389251988858	[1350]	[195,260]	0	hSpCas9	negative selection	1802509
45095046	45095069	20	+	26627737	HCT116	viability after 6 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.478217672481161	[476]	[10,155]	2	hSpCas9	negative selection	1802510
45095046	45095069	20	-	26627737	HCT116	viability after 6 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	1.2499755826821422	[473]	[416,44]	6	hSpCas9	negative selection	1802511
45097844	45097867	20	+	26627737	HCT116	viability after 6 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	1.030429112331528	[670]	[199,223]	5	hSpCas9	negative selection	1802512
45098410	45098433	20	-	26627737	HCT116	viability after 6 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.20431085943674943	[1260]	[202,154]	-1	hSpCas9	negative selection	1802513
45098658	45098681	20	+	26627737	HCT116	viability after 6 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	1.8472535414827247	[656]	[836,114]	8	hSpCas9	negative selection	1802514
45095011	45095034	20	+	26627737	HCT116	viability after 8 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.509260224119983	[442]	[394,286,360]	5	hSpCas9	negative selection	1884824
45095046	45095069	20	+	26627737	HCT116	viability after 8 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	1.0082354012842742	[156]	[209,164,147]	8	hSpCas9	negative selection	1884825
45095046	45095069	20	-	26627737	HCT116	viability after 8 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.9437904931226966	[131]	[230,102,87]	8	hSpCas9	negative selection	1884826
45097844	45097867	20	+	26627737	HCT116	viability after 8 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	0.2079572678255411	[321]	[152,181,277]	2	hSpCas9	negative selection	1884827
45098410	45098433	20	-	26627737	HCT116	viability after 8 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.07733223832283853	[633]	[343,365,394]	0	hSpCas9	negative selection	1884828
45098658	45098681	20	+	26627737	HCT116	viability after 8 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.10925627097689672	[688]	[384,278,391]	-1	hSpCas9	negative selection	1884829
45095011	45095034	20	+	26627737	HCT116	viability after 9 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.11207485895903346	[1350]	[266,486]	0	hSpCas9	negative selection	1967139
45095046	45095069	20	+	26627737	HCT116	viability after 9 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.31945499103702396	[476]	[273,67]	2	hSpCas9	negative selection	1967140
45095046	45095069	20	-	26627737	HCT116	viability after 9 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.21432652849758366	[473]	[114,171]	1	hSpCas9	negative selection	1967141
45097844	45097867	20	+	26627737	HCT116	viability after 9 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.3547825075910399	[670]	[181,106]	-2	hSpCas9	negative selection	1967142
45098410	45098433	20	-	26627737	HCT116	viability after 9 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.5554755266323996	[1260]	[605,406]	4	hSpCas9	negative selection	1967143
45098658	45098681	20	+	26627737	HCT116	viability after 9 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.5373492797790544	[656]	[224,277]	4	hSpCas9	negative selection	1967144
45095011	45095034	20	+	26627737	HCT116	viability after 12 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	1.1241381028012767	[442]	[437,446,641]	8	hSpCas9	negative selection	2049454
45095046	45095069	20	+	26627737	HCT116	viability after 12 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.7650253057911502	[156]	[80,187,157]	6	hSpCas9	negative selection	2049455
45095046	45095069	20	-	26627737	HCT116	viability after 12 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.5353428581108626	[131]	[89,160,52]	5	hSpCas9	negative selection	2049456
45097844	45097867	20	+	26627737	HCT116	viability after 12 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	0.2703125316276912	[321]	[176,135,299]	2	hSpCas9	negative selection	2049457
45098410	45098433	20	-	26627737	HCT116	viability after 12 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.591489966453774	[633]	[698,302,481]	5	hSpCas9	negative selection	2049458
45098658	45098681	20	+	26627737	HCT116	viability after 12 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.0822094411602996	[688]	[274,218,534]	-1	hSpCas9	negative selection	2049459
45095011	45095034	20	+	26627737	HCT116	viability after 15 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.8952723500955057	[442]	[415,553,442]	7	hSpCas9	negative selection	2131769
45095046	45095069	20	+	26627737	HCT116	viability after 15 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	1.071260354700616	[156]	[229,127,214]	8	hSpCas9	negative selection	2131770
45095046	45095069	20	-	26627737	HCT116	viability after 15 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	1.256593724112818	[131]	[317,140,101]	8	hSpCas9	negative selection	2131771
45097844	45097867	20	+	26627737	HCT116	viability after 15 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	0.37117418316432904	[321]	[130,219,351]	3	hSpCas9	negative selection	2131772
45098410	45098433	20	-	26627737	HCT116	viability after 15 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.5524035654572121	[633]	[679,515,424]	5	hSpCas9	negative selection	2131773
45098658	45098681	20	+	26627737	HCT116	viability after 15 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.2637159530923663	[688]	[339,533,533]	2	hSpCas9	negative selection	2131774
45095011	45095034	20	+	26627737	HCT116	viability after 18 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	1.2448772381006696	[442]	[439,592,482]	8	hSpCas9	negative selection	2214084
45095046	45095069	20	+	26627737	HCT116	viability after 18 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.47280778824001246	[156]	[80,123,109]	4	hSpCas9	negative selection	2214085
45095046	45095069	20	-	26627737	HCT116	viability after 18 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.46943789113749246	[131]	[145,90,24]	4	hSpCas9	negative selection	2214086
45097844	45097867	20	+	26627737	HCT116	viability after 18 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	0.6319374695591542	[321]	[311,183,230]	5	hSpCas9	negative selection	2214087
45098410	45098433	20	-	26627737	HCT116	viability after 18 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.9805020950070313	[633]	[533,636,642]	7	hSpCas9	negative selection	2214088
45098658	45098681	20	+	26627737	HCT116	viability after 18 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.43242552951103974	[688]	[179,209,357]	-4	hSpCas9	negative selection	2214089
45099177	45099200	20	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.3993627106801056	[4,4]	[3,6]	8	hSpCas9	positive selection	2996929
45098024	45098047	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCGAGTACCAGGCCCGCGAGG	KCNS1	ENSG00000124134	0.4417687441536452	[3,2]	[3,3]	8	hSpCas9	positive selection	2996930
45098525	45098548	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGGCCGCCTGCAGGCCGCGG	KCNS1	ENSG00000124134	-0.347854665700084	[2,2]	[1,1]	-5	hSpCas9	positive selection	2996931
45098018	45098041	20	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACCAGGCCCGCGAGGCGGCGG	KCNS1	ENSG00000124134	0.22384584776409366	[0,0]	[0,0]	5	hSpCas9	positive selection	2996932
45099177	45099200	20	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.9855175133588296	[4,4]	[5,6]	9	hSpCas9	positive selection	3064787
45098024	45098047	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCGAGTACCAGGCCCGCGAGG	KCNS1	ENSG00000124134	0.557115581634043	[3,3]	[1,4]	8	hSpCas9	positive selection	3064788
45098525	45098548	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGGCCGCCTGCAGGCCGCGG	KCNS1	ENSG00000124134	0.5323594204464429	[2,2]	[1,2]	8	hSpCas9	positive selection	3064789
45098018	45098041	20	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACCAGGCCCGCGAGGCGGCGG	KCNS1	ENSG00000124134	0.4833744715089985	[0,0]	[0,0]	8	hSpCas9	positive selection	3064790
45099154	45099177		+	24336571	A375	resistance to PLX after 7 days	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.07486081402575337	[15,11]	[14,10]	-2	hSpCas9	positive selection	3122579
45098324	45098347		+	24336571	A375	resistance to PLX after 7 days	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	-0.020879738871711573	[5,5]	[6,4]	0	hSpCas9	positive selection	3122580
45099163	45099186		-	24336571	A375	resistance to PLX after 7 days	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	0.037565609014693704	[14,11]	[12,13]	1	hSpCas9	positive selection	3122581
45099154	45099177		+	24336571	A375	resistance to PLX after 14 days	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.10201135959431423	[19,9]	[5,5]	-1	hSpCas9	positive selection	3180372
45098324	45098347		+	24336571	A375	resistance to PLX after 14 days	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.33456626969948844	[3,6]	[2,2]	3	hSpCas9	positive selection	3180373
45099163	45099186		-	24336571	A375	resistance to PLX after 14 days	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.699924349607697	[24,10]	[4,3]	-7	hSpCas9	positive selection	3180374
45099154	45099177		+	24336571	A375	viability after 7 days	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.3001971117306794	[11]	[15,11]	4	hSpCas9	negative selection	3238165
45098324	45098347		+	24336571	A375	viability after 7 days	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.042442955071599675	[5]	[5,5]	0	hSpCas9	negative selection	3238166
45099163	45099186		-	24336571	A375	viability after 7 days	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	0.43587359219117316	[9]	[14,11]	6	hSpCas9	negative selection	3238167
45099154	45099177		+	24336571	A375	viability after 14 days	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.43236447451674165	[11]	[19,9]	5	hSpCas9	negative selection	3295958
45098324	45098347		+	24336571	A375	viability after 14 days	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	-0.049533218557274106	[5]	[3,6]	0	hSpCas9	negative selection	3295959
45099163	45099186		-	24336571	A375	viability after 14 days	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	0.9006756248371869	[9]	[24,10]	9	hSpCas9	negative selection	3295960
45095184	45095207	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.0735906666687818	[160,160]	[0,0]	0	hSpCas9	positive selection	3375347
45099163	45099186	20	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	2.935398116558473	[19,19]	[0,0]	8	hSpCas9	positive selection	3375348
45099154	45099177	20	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.8141361511107891	[268,268]	[0,0]	-5	hSpCas9	positive selection	3375349
45099176	45099199	20	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	-0.512725886767564	[]	[]	-7	hSpCas9	negative selection	3434337
45098024	45098047	20	-	26780180	HT29	viability (Avana library 4 designs)	GCCCGAGTACCAGGCCCGCGAGG	KCNS1	ENSG00000124134	-0.096067498974194	[]	[]	-1	hSpCas9	negative selection	3434338
45098525	45098548	20	-	26780180	HT29	viability (Avana library 4 designs)	GCTGGGCCGCCTGCAGGCCGCGG	KCNS1	ENSG00000124134	2.58700886342786	[]	[]	8	hSpCas9	negative selection	3434339
45098018	45098041	20	-	26780180	HT29	viability (Avana library 4 designs)	GTACCAGGCCCGCGAGGCGGCGG	KCNS1	ENSG00000124134	0	[]	[]	0	hSpCas9	negative selection	3434340
45099176	45099199	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	4.75397929683376	[]	[]	7	hSpCas9	negative selection	3521394
45098024	45098047	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCGAGTACCAGGCCCGCGAGG	KCNS1	ENSG00000124134	6.08165143179012	[]	[]	9	hSpCas9	negative selection	3521395
45098525	45098548	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGGCCGCCTGCAGGCCGCGG	KCNS1	ENSG00000124134	5.58394689144037	[]	[]	8	hSpCas9	negative selection	3521396
45098018	45098041	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCAGGCCCGCGAGGCGGCGG	KCNS1	ENSG00000124134	0.757533880202146	[]	[]	1	hSpCas9	negative selection	3521397
45098508	45098531	20	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGCCTGCTCCTCCGACGCCGCGG	KCNS1	ENSG00000124134	4.78059117598183	[]	[]	7	hSpCas9	negative selection	3521398
45098480	45098503	20	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	-2.51632717801759	[]	[]	-3	hSpCas9	negative selection	3521399
45099176	45099199	20	+	26780180	A375	viability (Avana lentiGuide)	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.110820296583114	[]	[]	0	hSpCas9	negative selection	3630053
45098024	45098047	20	-	26780180	A375	viability (Avana lentiGuide)	GCCCGAGTACCAGGCCCGCGAGG	KCNS1	ENSG00000124134	7.12577822178328	[]	[]	5	hSpCas9	negative selection	3630054
45098525	45098548	20	-	26780180	A375	viability (Avana lentiGuide)	GCTGGGCCGCCTGCAGGCCGCGG	KCNS1	ENSG00000124134	4.55405668612877	[]	[]	4	hSpCas9	negative selection	3630055
45098018	45098041	20	-	26780180	A375	viability (Avana lentiGuide)	GTACCAGGCCCGCGAGGCGGCGG	KCNS1	ENSG00000124134	0	[]	[]	0	hSpCas9	negative selection	3630056
45098508	45098531	20	+	26780180	A375	viability (Avana lentiGuide)	CGCCTGCTCCTCCGACGCCGCGG	KCNS1	ENSG00000124134	-1.61574274710125	[]	[]	-3	hSpCas9	negative selection	3630057
45098480	45098503	20	-	26780180	A375	viability (Avana lentiGuide)	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0	[]	[]	0	hSpCas9	negative selection	3630058
45099176	45099199	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.19797187505715014	[5]	[6,5]	5	hSpCas9	positive selection	3738712
45098024	45098047	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCGAGTACCAGGCCCGCGAGG	KCNS1	ENSG00000124134	0.4322952702430761	[3]	[4,4]	9	hSpCas9	positive selection	3738713
45098525	45098548	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGGCCGCCTGCAGGCCGCGG	KCNS1	ENSG00000124134	0.37101362132670007	[4]	[5,5]	9	hSpCas9	positive selection	3738714
45098018	45098041	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCAGGCCCGCGAGGCGGCGG	KCNS1	ENSG00000124134	0.1296883034370081	[2]	[3,1]	3	hSpCas9	positive selection	3738715
45098508	45098531	20	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCCTGCTCCTCCGACGCCGCGG	KCNS1	ENSG00000124134	0.3395107988223267	[4]	[6,6]	8	hSpCas9	positive selection	3738716
45098480	45098503	20	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	-0.49846358782405153	[0]	[0,0]	-6	hSpCas9	positive selection	3738717
45099176	45099199	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.15254561390938026	[6]	[6,5]	3	hSpCas9	positive selection	3847319
45098024	45098047	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCGAGTACCAGGCCCGCGAGG	KCNS1	ENSG00000124134	-0.55435994070696	[4]	[1,3]	-6	hSpCas9	positive selection	3847320
45098525	45098548	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGGCCGCCTGCAGGCCGCGG	KCNS1	ENSG00000124134	-2.2481867277966927	[4]	[0,0]	-9	hSpCas9	positive selection	3847321
45098018	45098041	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCAGGCCCGCGAGGCGGCGG	KCNS1	ENSG00000124134	0.24644513604583196	[0]	[0,0]	6	hSpCas9	positive selection	3847322
45098508	45098531	20	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCCTGCTCCTCCGACGCCGCGG	KCNS1	ENSG00000124134	0.23916741429080032	[6]	[6,5]	6	hSpCas9	positive selection	3847323
45098480	45098503	20	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.24644513604583196	[0]	[0,0]	6	hSpCas9	positive selection	3847324
45098384	45098407	20	+	26780180	A375	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	1.58145765522144	[]	[]	8	hSpCas9	negative selection	3953329
45095184	45095207	20	-	26780180	A375	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	1.5012491356394	[]	[]	8	hSpCas9	negative selection	3953330
45099154	45099177	20	+	26780180	A375	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	1.43277537974925	[]	[]	8	hSpCas9	negative selection	3953331
45098324	45098347	20	+	26780180	A375	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.49799756065089	[]	[]	1	hSpCas9	negative selection	3953332
45094935	45094958	20	-	26780180	A375	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.97095164076951	[]	[]	4	hSpCas9	negative selection	3953333
45099163	45099186	20	-	26780180	A375	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	1.29261746370183	[]	[]	7	hSpCas9	negative selection	3953334
45098384	45098407	20	+	26780180	HT29	viability (GeCKOv2 library)	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	1.49969537559859	[]	[]	7	hSpCas9	negative selection	4061295
45095184	45095207	20	-	26780180	HT29	viability (GeCKOv2 library)	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	1.26401477597276	[]	[]	6	hSpCas9	negative selection	4061296
45099154	45099177	20	+	26780180	HT29	viability (GeCKOv2 library)	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	1.04050203546609	[]	[]	5	hSpCas9	negative selection	4061297
45098324	45098347	20	+	26780180	HT29	viability (GeCKOv2 library)	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.384958910770098	[]	[]	1	hSpCas9	negative selection	4061298
45094935	45094958	20	-	26780180	HT29	viability (GeCKOv2 library)	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.953129734742337	[]	[]	4	hSpCas9	negative selection	4061299
45099163	45099186	20	-	26780180	HT29	viability (GeCKOv2 library)	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	1.40381243386798	[]	[]	7	hSpCas9	negative selection	4061300
45099154	45099177	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.492521082966041	[3]	[4,2]	9	hSpCas9	positive selection	4146361
45098324	45098347	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	-0.020803273467209837	[2]	[1,1]	0	hSpCas9	positive selection	4146362
45099163	45099186	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	0.1157467143543898	[3]	[2,2]	3	hSpCas9	positive selection	4146363
45099154	45099177	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.09894635205712374	[2]	[2,2,0,0]	0	hSpCas9	positive selection	4210383
45098324	45098347	20	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	-0.8206079853548225	[4]	[0,0,1,0]	-9	hSpCas9	positive selection	4210384
45099163	45099186	20	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.1573780657482381	[3]	[0,0,3,0]	-2	hSpCas9	positive selection	4210385
45098324	45098347	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.53490776787439	[2]	[3,3]	9	hSpCas9	positive selection	4278062
45098384	45098407	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.31254604946673387	[3]	[2,1]	-6	hSpCas9	positive selection	4278063
45094935	45094958	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	-0.10125318083191942	[2]	[2,1]	-2	hSpCas9	positive selection	4278064
45095184	45095207	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.4231658134532758	[3]	[2,0]	-7	hSpCas9	positive selection	4342318
45099163	45099186	20	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.060863900408068106	[1]	[1,0]	-1	hSpCas9	positive selection	4342319
45099154	45099177	20	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.13870369885143555	[3]	[3,2]	2	hSpCas9	positive selection	4342320
45098188	45098210	20	-	27760321	OCIAML3	viability	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.3049434868895914	[492,455]	[296,668]	3	hSpCas9	negative selection	4411535
45098216	45098238	20	+	27760321	OCIAML3	viability	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	0.9881380148108191	[892,693]	[1214,1231]	9	hSpCas9	negative selection	4411536
45098292	45098314	20	-	27760321	OCIAML3	viability	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.07783133434494777	[592,462]	[342,549]	0	hSpCas9	negative selection	4411537
45098325	45098347	20	+	27760321	OCIAML3	viability	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	-0.17090096586748427	[564,457]	[316,400]	-2	hSpCas9	negative selection	4411538
45098634	45098656	20	-	27760321	OCIAML3	viability	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.3168811452758278	[1008,824]	[805,996]	3	hSpCas9	negative selection	4411539
45098188	45098210	20	-	27760321	OCIAML2	viability	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.426917450273158	[492,455]	[462,585]	6	hSpCas9	negative selection	4494998
45098216	45098238	20	+	27760321	OCIAML2	viability	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	0.6500892675248598	[892,693]	[960,1051]	8	hSpCas9	negative selection	4494999
45098292	45098314	20	-	27760321	OCIAML2	viability	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.09802892424169851	[592,462]	[384,544]	1	hSpCas9	negative selection	4495000
45098325	45098347	20	+	27760321	OCIAML2	viability	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.33673705566120704	[564,457]	[486,562]	4	hSpCas9	negative selection	4495001
45098634	45098656	20	-	27760321	OCIAML2	viability	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	-0.045259454368085095	[1008,824]	[726,699]	0	hSpCas9	negative selection	4495002
45098188	45098210	20	-	27760321	MV411	viability	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.6104558105181277	[492,455]	[595,300]	4	hSpCas9	negative selection	4578461
45098216	45098238	20	+	27760321	MV411	viability	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	1.2293773163306403	[892,693]	[894,1705]	8	hSpCas9	negative selection	4578462
45098292	45098314	20	-	27760321	MV411	viability	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	-0.06867070940206407	[592,462]	[287,392]	0	hSpCas9	negative selection	4578463
45098325	45098347	20	+	27760321	MV411	viability	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	1.4286160674083634	[564,457]	[1143,542]	9	hSpCas9	negative selection	4578464
45098634	45098656	20	-	27760321	MV411	viability	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.020264043376742702	[1008,824]	[188,1243]	0	hSpCas9	negative selection	4578465
45098188	45098210	20	-	27760321	HL60	viability	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.4202929977865232	[492,455]	[476,562]	5	hSpCas9	negative selection	4661924
45098216	45098238	20	+	27760321	HL60	viability	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	-0.09574875732649724	[892,693]	[529,678]	-1	hSpCas9	negative selection	4661925
45098292	45098314	20	-	27760321	HL60	viability	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.13362630271126247	[592,462]	[467,471]	1	hSpCas9	negative selection	4661926
45098325	45098347	20	+	27760321	HL60	viability	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	-0.09333108938919085	[564,457]	[325,456]	-1	hSpCas9	negative selection	4661927
45098634	45098656	20	-	27760321	HL60	viability	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.11470639450534215	[1008,824]	[758,857]	1	hSpCas9	negative selection	4661928
45098188	45098210	20	-	27760321	HT1080	viability	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	-3.355884365249668	[455,355]	[0,31]	-7	hSpCas9	negative selection	4745387
45098216	45098238	20	+	27760321	HT1080	viability	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	1.6139821462674906	[693,541]	[597,923]	8	hSpCas9	negative selection	4745388
45098292	45098314	20	-	27760321	HT1080	viability	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.844645607163578	[462,360]	[288,300]	4	hSpCas9	negative selection	4745389
45098325	45098347	20	+	27760321	HT1080	viability	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.3503438080731458	[457,357]	[190,224]	1	hSpCas9	negative selection	4745390
45098634	45098656	20	-	27760321	HT1080	viability	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.4111443566774631	[824,643]	[527,236]	2	hSpCas9	negative selection	4745391
45098188	45098210	20	-	27760321	HT29	viability after 7 days	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	-0.021882333960814987	[455,355]	[421,478,623]	0	hSpCas9	negative selection	4828850
45098216	45098238	20	+	27760321	HT29	viability after 7 days	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	0.7222634241829273	[693,541]	[1309,1223,1393]	9	hSpCas9	negative selection	4828851
45098292	45098314	20	-	27760321	HT29	viability after 7 days	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.3583718978831564	[462,360]	[636,804,590]	5	hSpCas9	negative selection	4828852
45098325	45098347	20	+	27760321	HT29	viability after 7 days	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.46521443546577834	[457,357]	[927,619,654]	7	hSpCas9	negative selection	4828853
45098634	45098656	20	-	27760321	HT29	viability after 7 days	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.15600208690940343	[824,643]	[926,1181,1028]	2	hSpCas9	negative selection	4828854
45098188	45098210	20	-	27760321	HT29	viability after 25 days	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.6242865580086695	[455,355]	[952,526,641]	7	hSpCas9	negative selection	4912313
45098216	45098238	20	+	27760321	HT29	viability after 25 days	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	1.0310497035859567	[693,541]	[1057,1583,1740]	9	hSpCas9	negative selection	4912314
45098292	45098314	20	-	27760321	HT29	viability after 25 days	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.7725215345209413	[462,360]	[581,1009,836]	8	hSpCas9	negative selection	4912315
45098325	45098347	20	+	27760321	HT29	viability after 25 days	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	1.0015026422215527	[457,357]	[765,704,1385]	9	hSpCas9	negative selection	4912316
45098634	45098656	20	-	27760321	HT29	viability after 25 days	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.6552762767751465	[824,643]	[1246,1319,1410]	7	hSpCas9	negative selection	4912317
45098188	45098210	20	-	27760321	HT29	viability after 22 days	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.8755468038244169	[455,355]	[849,736,997]	8	hSpCas9	negative selection	4995776
45098216	45098238	20	+	27760321	HT29	viability after 22 days	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	1.2100448241681216	[693,541]	[1641,1755,1559]	9	hSpCas9	negative selection	4995777
45098292	45098314	20	-	27760321	HT29	viability after 22 days	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.811676211845064	[462,360]	[683,1091,734]	8	hSpCas9	negative selection	4995778
45098325	45098347	20	+	27760321	HT29	viability after 22 days	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.8918040039119801	[457,357]	[993,704,923]	8	hSpCas9	negative selection	4995779
45098634	45098656	20	-	27760321	HT29	viability after 22 days	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.7558337103321537	[824,643]	[1668,1517,1104]	8	hSpCas9	negative selection	4995780
45098188	45098210	20	-	27760321	HT29	viability after 19 days	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.5479276908935223	[455,355]	[755,764,528]	5	hSpCas9	negative selection	5079239
45098216	45098238	20	+	27760321	HT29	viability after 19 days	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	0.8554219241568055	[693,541]	[1435,1321,1100]	8	hSpCas9	negative selection	5079240
45098292	45098314	20	-	27760321	HT29	viability after 19 days	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.6847986086539493	[462,360]	[727,740,797]	7	hSpCas9	negative selection	5079241
45098325	45098347	20	+	27760321	HT29	viability after 19 days	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.9887124598504662	[457,357]	[849,736,1172]	8	hSpCas9	negative selection	5079242
45098634	45098656	20	-	27760321	HT29	viability after 19 days	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.5252393048486428	[824,643]	[1255,1353,1027]	5	hSpCas9	negative selection	5079243
45098188	45098210	20	-	27760321	HT29	viability after 16 days	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	-0.05307039625027861	[455,355]	[616,336,378]	0	hSpCas9	negative selection	5162702
45098216	45098238	20	+	27760321	HT29	viability after 16 days	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	0.9047690074615697	[693,541]	[1422,1432,1035]	9	hSpCas9	negative selection	5162703
45098292	45098314	20	-	27760321	HT29	viability after 16 days	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.8565887865121353	[462,360]	[846,1135,513]	8	hSpCas9	negative selection	5162704
45098325	45098347	20	+	27760321	HT29	viability after 16 days	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.8761011480304801	[457,357]	[821,647,1046]	9	hSpCas9	negative selection	5162705
45098634	45098656	20	-	27760321	HT29	viability after 16 days	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.7777345429792613	[824,643]	[1463,1546,1216]	8	hSpCas9	negative selection	5162706
45098188	45098210	20	-	27760321	HT29	viability after 13 days	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	-0.08006406610141507	[455,355]	[508,338,485]	-1	hSpCas9	negative selection	5246165
45098216	45098238	20	+	27760321	HT29	viability after 13 days	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	1.0073353178068802	[693,541]	[1279,1757,1294]	9	hSpCas9	negative selection	5246166
45098292	45098314	20	-	27760321	HT29	viability after 13 days	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.2736736025590112	[462,360]	[489,709,535]	3	hSpCas9	negative selection	5246167
45098325	45098347	20	+	27760321	HT29	viability after 13 days	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6973359116584538	[457,357]	[699,890,714]	8	hSpCas9	negative selection	5246168
45098634	45098656	20	-	27760321	HT29	viability after 13 days	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.4593903934814705	[824,643]	[1024,1335,1154]	6	hSpCas9	negative selection	5246169
45098188	45098210	20	-	27760321	HT29	viability after 10 days	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	-0.39766256111871434	[455,355]	[453,266,428]	-5	hSpCas9	negative selection	5329628
45098216	45098238	20	+	27760321	HT29	viability after 10 days	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	0.8854519772396952	[693,541]	[1699,1538,1048]	9	hSpCas9	negative selection	5329629
45098292	45098314	20	-	27760321	HT29	viability after 10 days	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	0.620819182963422	[462,360]	[1023,810,543]	8	hSpCas9	negative selection	5329630
45098325	45098347	20	+	27760321	HT29	viability after 10 days	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6422465213737735	[457,357]	[1140,854,399]	8	hSpCas9	negative selection	5329631
45098634	45098656	20	-	27760321	HT29	viability after 10 days	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	0.11165757396318554	[824,643]	[1031,1183,766]	1	hSpCas9	negative selection	5329632
45098188	45098210	20	-	27760321	MOLM13	viability	AGCGAGAACTGGCGCGCTATGG	KCNS1	ENSG00000124134	0.1795949498283069	[492,455]	[353,259]	1	hSpCas9	negative selection	5413091
45098216	45098238	20	+	27760321	MOLM13	viability	CGGAGATCTCGTCGGGGCACGG	KCNS1	ENSG00000124134	1.781299441046074	[892,693]	[1062,1923]	9	hSpCas9	negative selection	5413092
45098292	45098314	20	-	27760321	MOLM13	viability	CGCGCGCTACCTGGAGAGGCGG	KCNS1	ENSG00000124134	-0.19280350877505195	[592,462]	[354,176]	-1	hSpCas9	negative selection	5413093
45098325	45098347	20	+	27760321	MOLM13	viability	GGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5784387607840807	[564,457]	[224,601]	4	hSpCas9	negative selection	5413094
45098634	45098656	20	-	27760321	MOLM13	viability	CGACACCGGGATCCGCTGGCGG	KCNS1	ENSG00000124134	1.4487700473600604	[1008,824]	[1508,1316]	8	hSpCas9	negative selection	5413095
45100887	45100910	20	+	27661255	K562	viability	GGAGCCACGTCCCTCCCCAAAGG	KCNS1	ENSG00000124134	0.060040327268990556	[1017,1166]	[994,832]	2	dCas9-KRAB	negative selection	5488083
45100915	45100938	20	-	27661255	K562	viability	GGGAGGTGCCACCACAGGTAAGG	KCNS1	ENSG00000124134	-0.03877269494684832	[1570,1576]	[1353,1112]	-1	dCas9-KRAB	negative selection	5488084
45100980	45101003	20	-	27661255	K562	viability	GCGAGACCGAGTATAGCCAGCGG	KCNS1	ENSG00000124134	-0.05557048477547549	[538,556]	[522,333]	-2	dCas9-KRAB	negative selection	5488085
45101074	45101097	20	-	27661255	K562	viability	GCCTTCAGCCGCGGGGGACTAGG	KCNS1	ENSG00000124134	-0.076426958137786	[429,493]	[441,269]	-3	dCas9-KRAB	negative selection	5488086
45101080	45101103	20	-	27661255	K562	viability	GATGCGGCCTTCAGCCGCGGGGG	KCNS1	ENSG00000124134	0.07704631189871958	[349,491]	[391,318]	2	dCas9-KRAB	negative selection	5488087
45098324	45098347	20	+	27260156	BXPC3	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5106578833831494	[419]	[651,459,676,729]	9	hSpCas9	negative selection	5550522
45098384	45098407	20	+	27260156	BXPC3	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.33386563016573	[939]	[584,666,932,984]	-6	hSpCas9	negative selection	5550523
45094935	45094958	20	-	27260156	BXPC3	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.35201869847853945	[385]	[409,508,635,515]	7	hSpCas9	negative selection	5550524
45095184	45095207	20	-	27260156	BXPC3	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.037534187227943806	[469]	[540,347,413,626]	-1	hSpCas9	negative selection	5614778
45099163	45099186	20	-	27260156	BXPC3	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.46728041442096413	[140]	[134,106,81,96]	-7	hSpCas9	negative selection	5614779
45099154	45099177	20	+	27260156	BXPC3	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.08947223157290041	[634]	[555,588,693,668]	-2	hSpCas9	negative selection	5614780
45098324	45098347	20	+	27260156	A673	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6642469206716002	[419]	[900,714,781,811]	9	hSpCas9	negative selection	5671773
45098384	45098407	20	+	27260156	A673	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.04860026420108032	[939]	[1255,1060,987,1077]	-1	hSpCas9	negative selection	5671774
45094935	45094958	20	-	27260156	A673	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.29957473076119406	[385]	[670,595,434,591]	7	hSpCas9	negative selection	5671775
45095184	45095207	20	-	27260156	A673	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.2415263458625098	[469]	[493,445,464,507]	-5	hSpCas9	negative selection	5736029
45099163	45099186	20	-	27260156	A673	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.9248608081189411	[140]	[75,85,73,120]	-9	hSpCas9	negative selection	5736030
45099154	45099177	20	+	27260156	A673	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.20559268486246007	[634]	[762,573,797,512]	-5	hSpCas9	negative selection	5736031
45098324	45098347	20	+	27260156	A375	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6668855149301118	[419]	[715,827,909,676]	8	hSpCas9	negative selection	5793024
45098384	45098407	20	+	27260156	A375	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.12176910207255831	[939]	[1114,1140,1013,805]	-2	hSpCas9	negative selection	5793025
45094935	45094958	20	-	27260156	A375	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.31811492449919315	[385]	[653,812,449,385]	4	hSpCas9	negative selection	5793026
45095184	45095207	20	-	27260156	A375	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.03614404695163984	[469]	[547,579,595,433]	0	hSpCas9	negative selection	5857280
45099163	45099186	20	-	27260156	A375	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.4068486822624615	[140]	[137,115,76,159]	-5	hSpCas9	negative selection	5857281
45099154	45099177	20	+	27260156	A375	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.06127034831707784	[634]	[654,1069,628,554]	-1	hSpCas9	negative selection	5857282
45098324	45098347	20	+	27260156	COLO741	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7045991761789056	[419]	[991,800,840]	9	hSpCas9	negative selection	5914275
45098384	45098407	20	+	27260156	COLO741	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.1482225276287723	[939]	[1664,1374,1002]	3	hSpCas9	negative selection	5914276
45094935	45094958	20	-	27260156	COLO741	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.32522856725573923	[385]	[599,648,602]	6	hSpCas9	negative selection	5914277
45095184	45095207	20	-	27260156	COLO741	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.0409083989027662	[469]	[604,734,423]	-1	hSpCas9	negative selection	5978531
45099163	45099186	20	-	27260156	COLO741	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.18543746908202663	[140]	[126,56,278]	-4	hSpCas9	negative selection	5978532
45099154	45099177	20	+	27260156	COLO741	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.08650107778051402	[634]	[721,1182,679]	1	hSpCas9	negative selection	5978533
45098324	45098347	20	+	27260156	CAL120	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.4925669169065724	[419]	[878,707,641]	7	hSpCas9	negative selection	6035526
45098384	45098407	20	+	27260156	CAL120	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.1710462400282331	[939]	[1242,1031,1657]	2	hSpCas9	negative selection	6035527
45094935	45094958	20	-	27260156	CAL120	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.18823765691076194	[385]	[563,525,553]	3	hSpCas9	negative selection	6035528
45095184	45095207	20	-	27260156	CAL120	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.16664377512112383	[469]	[623,407,545]	-2	hSpCas9	negative selection	6099782
45099163	45099186	20	-	27260156	CAL120	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.130954019229424	[140]	[113,83,47]	-9	hSpCas9	negative selection	6099783
45099154	45099177	20	+	27260156	CAL120	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.06740050322720992	[634]	[602,920,715]	-1	hSpCas9	negative selection	6099784
45098324	45098347	20	+	27260156	CADOES1	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7081483255461956	[419]	[796,524,770,451]	9	hSpCas9	negative selection	6156777
45098384	45098407	20	+	27260156	CADOES1	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.0630901843619025	[939]	[736,792,840,981]	-1	hSpCas9	negative selection	6156778
45094935	45094958	20	-	27260156	CADOES1	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.2495760008942994	[385]	[390,459,438,416]	4	hSpCas9	negative selection	6156779
45095184	45095207	20	-	27260156	CADOES1	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	0.02520816496247505	[469]	[329,559,415,474]	0	hSpCas9	negative selection	6221033
45099163	45099186	20	-	27260156	CADOES1	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.3803821640354321	[140]	[94,66,137,102]	-6	hSpCas9	negative selection	6221034
45099154	45099177	20	+	27260156	CADOES1	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.07448941560683875	[634]	[502,641,608,486]	-1	hSpCas9	negative selection	6221035
45098324	45098347	20	+	27260156	EWS502	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7018133647044781	[419]	[667,602,794,846]	9	hSpCas9	negative selection	6278028
45098384	45098407	20	+	27260156	EWS502	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.07540621327208719	[939]	[709,983,1006,1114]	-1	hSpCas9	negative selection	6278029
45094935	45094958	20	-	27260156	EWS502	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.6063945752318716	[385]	[513,597,809,578]	9	hSpCas9	negative selection	6278030
45095184	45095207	20	-	27260156	EWS502	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.07692253731251449	[469]	[546,429,509,385]	-1	hSpCas9	negative selection	6342284
45099163	45099186	20	-	27260156	EWS502	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.09264516884629148	[140]	[88,97,241,139]	-2	hSpCas9	negative selection	6342285
45099154	45099177	20	+	27260156	EWS502	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.11524242852423133	[634]	[842,797,595,649]	2	hSpCas9	negative selection	6342286
45098324	45098347	20	+	27260156	EW8	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5290378664637291	[419]	[532,545,426,472]	8	hSpCas9	negative selection	6399279
45098384	45098407	20	+	27260156	EW8	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.2725262247062269	[939]	[680,466,589,793]	-5	hSpCas9	negative selection	6399280
45094935	45094958	20	-	27260156	EW8	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.04054863163691591	[385]	[304,268,253,466]	0	hSpCas9	negative selection	6399281
45095184	45095207	20	-	27260156	EW8	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.3604520959805165	[469]	[472,330,194,223]	-6	hSpCas9	negative selection	6463535
45099163	45099186	20	-	27260156	EW8	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.075824142502331	[140]	[13,74,73,45]	-9	hSpCas9	negative selection	6463536
45099154	45099177	20	+	27260156	EW8	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.21087436448347294	[634]	[509,437,351,499]	-4	hSpCas9	negative selection	6463537
45098324	45098347	20	+	27260156	CORL105	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5403375974411192	[419]	[564,881,735,671]	8	hSpCas9	negative selection	6520530
45098384	45098407	20	+	27260156	CORL105	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.026433597843475543	[939]	[1308,863,1195,1136]	0	hSpCas9	negative selection	6520531
45094935	45094958	20	-	27260156	CORL105	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.2400523071466249	[385]	[628,551,633,338]	4	hSpCas9	negative selection	6520532
45095184	45095207	20	-	27260156	CORL105	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	0.13450800334678154	[469]	[574,630,608,599]	2	hSpCas9	negative selection	6584786
45099163	45099186	20	-	27260156	CORL105	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.759545052743144	[140]	[38,94,148,112]	-8	hSpCas9	negative selection	6584787
45099154	45099177	20	+	27260156	CORL105	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.22302681030955462	[634]	[507,546,812,703]	-4	hSpCas9	negative selection	6584788
45098324	45098347	20	+	27260156	HS294T	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	1.1492517226263155	[419]	[246,317,586,287]	9	hSpCas9	negative selection	6641781
45098384	45098407	20	+	27260156	HS294T	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.13469219084703687	[939]	[309,439,352,518]	1	hSpCas9	negative selection	6641782
45094935	45094958	20	-	27260156	HS294T	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.15396217651874278	[385]	[120,152,210,186]	2	hSpCas9	negative selection	6641783
45095184	45095207	20	-	27260156	HS294T	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.5767857891182472	[469]	[134,78,121,156]	-7	hSpCas9	negative selection	6706037
45099163	45099186	20	-	27260156	HS294T	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	0.039354364680342035	[140]	[26,33,22,160]	0	hSpCas9	negative selection	6706038
45099154	45099177	20	+	27260156	HS294T	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.08686105380873721	[634]	[278,179,225,236]	-1	hSpCas9	negative selection	6706039
45098324	45098347	20	+	27260156	HCC44	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.29622858638003136	[419]	[610,591,658,483]	5	hSpCas9	negative selection	6763032
45098384	45098407	20	+	27260156	HCC44	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.037119585759771145	[939]	[1264,764,1208,987]	0	hSpCas9	negative selection	6763033
45094935	45094958	20	-	27260156	HCC44	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.4316624178525039	[385]	[715,499,586,571]	7	hSpCas9	negative selection	6763034
45095184	45095207	20	-	27260156	HCC44	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.1846424743517055	[469]	[740,285,435,449]	-3	hSpCas9	negative selection	6827288
45099163	45099186	20	-	27260156	HCC44	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.9046669480938239	[140]	[103,68,74,93]	-8	hSpCas9	negative selection	6827289
45099154	45099177	20	+	27260156	HCC44	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.22786864449700114	[634]	[664,469,675,670]	-4	hSpCas9	negative selection	6827290
45098324	45098347	20	+	27260156	G402	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.8052603528444631	[419]	[909,734,893,1025]	8	hSpCas9	negative selection	6884283
45098384	45098407	20	+	27260156	G402	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.049960513703174	[939]	[1360,1167,1413,842]	0	hSpCas9	negative selection	6884284
45094935	45094958	20	-	27260156	G402	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.30506974990681957	[385]	[428,446,594,812]	4	hSpCas9	negative selection	6884285
45095184	45095207	20	-	27260156	G402	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.08929227455813639	[469]	[613,448,434,655]	-1	hSpCas9	negative selection	6948539
45099163	45099186	20	-	27260156	G402	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.8714365312791343	[140]	[58,106,19,8]	-9	hSpCas9	negative selection	6948540
45099154	45099177	20	+	27260156	G402	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.15052299243748052	[634]	[764,1385,661,650]	2	hSpCas9	negative selection	6948541
45098324	45098347	20	+	27260156	L33	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6137747111454375	[419]	[689,270,382,608]	9	hSpCas9	negative selection	7005534
45098384	45098407	20	+	27260156	L33	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.25290119057671445	[939]	[859,449,757,1320]	5	hSpCas9	negative selection	7005535
45094935	45094958	20	-	27260156	L33	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.2156301703918106	[385]	[368,182,314,477]	5	hSpCas9	negative selection	7005536
45095184	45095207	20	-	27260156	L33	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.043338291559630204	[469]	[391,189,323,454]	-1	hSpCas9	negative selection	7069790
45099163	45099186	20	-	27260156	L33	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.434971098693106	[140]	[61,23,31,36]	-9	hSpCas9	negative selection	7069791
45099154	45099177	20	+	27260156	L33	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.030913634792871403	[634]	[631,299,417,566]	0	hSpCas9	negative selection	7069792
45098324	45098347	20	+	27260156	K562	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7547609941975713	[419]	[633,606,960,343]	8	hSpCas9	negative selection	7126785
45098384	45098407	20	+	27260156	K562	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.1840036175963915	[939]	[1146,889,1023,760]	2	hSpCas9	negative selection	7126786
45094935	45094958	20	-	27260156	K562	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.23566145715412548	[385]	[255,759,186,413]	3	hSpCas9	negative selection	7126787
45095184	45095207	20	-	27260156	K562	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.1410667233974322	[469]	[252,389,454,400]	-2	hSpCas9	negative selection	7191041
45099163	45099186	20	-	27260156	K562	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.7595360675341933	[140]	[94,5,179,18]	-7	hSpCas9	negative selection	7191042
45099154	45099177	20	+	27260156	K562	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.3367955433474609	[634]	[358,329,920,189]	-4	hSpCas9	negative selection	7191043
45098324	45098347	20	+	27260156	HT29	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7187714758407363	[419]	[829,780,1004,744]	9	hSpCas9	negative selection	7248036
45098384	45098407	20	+	27260156	HT29	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.03992152114403402	[939]	[1161,1230,1303,1016]	0	hSpCas9	negative selection	7248037
45094935	45094958	20	-	27260156	HT29	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.42946665691635927	[385]	[646,644,669,570]	8	hSpCas9	negative selection	7248038
45095184	45095207	20	-	27260156	HT29	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.1661625023581783	[469]	[652,514,487,401]	-3	hSpCas9	negative selection	7312292
45099163	45099186	20	-	27260156	HT29	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.8748646708832879	[140]	[199,32,83,62]	-8	hSpCas9	negative selection	7312293
45099154	45099177	20	+	27260156	HT29	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.06797573536641527	[634]	[1049,888,641,689]	1	hSpCas9	negative selection	7312294
45098324	45098347	20	+	27260156	MHHES1	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7815691783922294	[419]	[956,787,893,648]	9	hSpCas9	negative selection	7369287
45098384	45098407	20	+	27260156	MHHES1	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.12800458200069353	[939]	[819,953,1197,882]	-2	hSpCas9	negative selection	7369288
45094935	45094958	20	-	27260156	MHHES1	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.3772565492359771	[385]	[643,657,682,334]	6	hSpCas9	negative selection	7369289
45095184	45095207	20	-	27260156	MHHES1	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.24764712382965962	[469]	[579,523,418,306]	-5	hSpCas9	negative selection	7433543
45099163	45099186	20	-	27260156	MHHES1	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.5907515029955397	[140]	[156,109,59,99]	-8	hSpCas9	negative selection	7433544
45099154	45099177	20	+	27260156	MHHES1	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.2713473347996539	[634]	[543,685,619,525]	-5	hSpCas9	negative selection	7433545
45098324	45098347	20	+	27260156	MEWO	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.4228249778453478	[419]	[498,476,598]	8	hSpCas9	negative selection	7490538
45098384	45098407	20	+	27260156	MEWO	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.15688568134034964	[939]	[1125,845,997]	3	hSpCas9	negative selection	7490539
45094935	45094958	20	-	27260156	MEWO	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.22092473090068182	[385]	[509,385,383]	5	hSpCas9	negative selection	7490540
45095184	45095207	20	-	27260156	MEWO	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.22013928089307744	[469]	[571,389,207]	-5	hSpCas9	negative selection	7554794
45099163	45099186	20	-	27260156	MEWO	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.6615831299834951	[140]	[76,67,103]	-8	hSpCas9	negative selection	7554795
45099154	45099177	20	+	27260156	MEWO	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.018627540300310108	[634]	[585,644,570]	0	hSpCas9	negative selection	7554796
45098324	45098347	20	+	27260156	LNCAPCLONEFGC	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6225063816581186	[419]	[587,522,668,578]	8	hSpCas9	negative selection	7611789
45098384	45098407	20	+	27260156	LNCAPCLONEFGC	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.09718052771381558	[939]	[544,834,1072,773]	-1	hSpCas9	negative selection	7611790
45094935	45094958	20	-	27260156	LNCAPCLONEFGC	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.3105063262029506	[385]	[460,460,420,386]	5	hSpCas9	negative selection	7611791
45095184	45095207	20	-	27260156	LNCAPCLONEFGC	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.0028017302831583003	[469]	[372,394,556,396]	0	hSpCas9	negative selection	7676045
45099163	45099186	20	-	27260156	LNCAPCLONEFGC	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.620157915900178	[140]	[114,49,76,90]	-7	hSpCas9	negative selection	7676046
45099154	45099177	20	+	27260156	LNCAPCLONEFGC	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.3466370588219184	[634]	[500,435,490,386]	-5	hSpCas9	negative selection	7676047
45098324	45098347	20	+	27260156	PANC0327	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7619298099102281	[419]	[663,450,467,972]	9	hSpCas9	negative selection	7733040
45098384	45098407	20	+	27260156	PANC0327	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.10224389195529959	[939]	[645,905,798,732]	-1	hSpCas9	negative selection	7733041
45094935	45094958	20	-	27260156	PANC0327	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.11240281604701804	[385]	[408,343,303,431]	1	hSpCas9	negative selection	7733042
45095184	45095207	20	-	27260156	PANC0327	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.20426501180667544	[469]	[368,360,294,424]	-3	hSpCas9	negative selection	7797296
45099163	45099186	20	-	27260156	PANC0327	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.068134164808648	[140]	[59,105,53,12]	-8	hSpCas9	negative selection	7797297
45099154	45099177	20	+	27260156	PANC0327	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.10258295282626279	[634]	[661,583,677,505]	1	hSpCas9	negative selection	7797298
45098324	45098347	20	+	27260156	NCIH2009	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6876890171523856	[419]	[1206,815,864]	8	hSpCas9	negative selection	7854291
45098384	45098407	20	+	27260156	NCIH2009	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.09437507010636104	[939]	[1551,1323,1358]	1	hSpCas9	negative selection	7854292
45094935	45094958	20	-	27260156	NCIH2009	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.36210597812611817	[385]	[776,576,742]	5	hSpCas9	negative selection	7854293
45095184	45095207	20	-	27260156	NCIH2009	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	0.19105342926929075	[469]	[659,1021,542]	2	hSpCas9	negative selection	7918547
45099163	45099186	20	-	27260156	NCIH2009	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.6561514589031956	[140]	[145,67,165]	-7	hSpCas9	negative selection	7918548
45099154	45099177	20	+	27260156	NCIH2009	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.3061371910147632	[634]	[801,726,638]	-4	hSpCas9	negative selection	7918549
45098324	45098347	20	+	27260156	NCIH1373	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	1.1231227787778149	[419]	[565,984,1108,364]	9	hSpCas9	negative selection	7975542
45098384	45098407	20	+	27260156	NCIH1373	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.20716146651485778	[939]	[1603,606,1381,367]	2	hSpCas9	negative selection	7975543
45094935	45094958	20	-	27260156	NCIH1373	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.27531512225437876	[385]	[604,329,553,168]	2	hSpCas9	negative selection	7975544
45095184	45095207	20	-	27260156	NCIH1373	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.6165931039130959	[469]	[310,166,445,122]	-6	hSpCas9	negative selection	8039798
45099163	45099186	20	-	27260156	NCIH1373	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.5925203694662595	[140]	[159,166,27,16]	-5	hSpCas9	negative selection	8039799
45099154	45099177	20	+	27260156	NCIH1373	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.1367968120976722	[634]	[698,571,357,262]	-1	hSpCas9	negative selection	8039800
45098324	45098347	20	+	27260156	PATU8902	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	1.2968774972185733	[419]	[1648,1566,827,1904]	9	hSpCas9	negative selection	8096793
45098384	45098407	20	+	27260156	PATU8902	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.06661616172659102	[939]	[1884,913,1176,1561]	0	hSpCas9	negative selection	8096794
45094935	45094958	20	-	27260156	PATU8902	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.6196207732389478	[385]	[519,1178,377,1411]	6	hSpCas9	negative selection	8096795
45095184	45095207	20	-	27260156	PATU8902	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	0.30452723998564685	[469]	[900,833,647,894]	3	hSpCas9	negative selection	8161049
45099163	45099186	20	-	27260156	PATU8902	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.1885950965474426	[140]	[73,103,7,190]	-8	hSpCas9	negative selection	8161050
45099154	45099177	20	+	27260156	PATU8902	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.17348577985135144	[634]	[945,669,944,1492]	1	hSpCas9	negative selection	8161051
45098324	45098347	20	+	27260156	PANC1	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5701766314787717	[419]	[449,841,581,354]	8	hSpCas9	negative selection	8218044
45098384	45098407	20	+	27260156	PANC1	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.35122594095856563	[939]	[703,829,556,491]	-5	hSpCas9	negative selection	8218045
45094935	45094958	20	-	27260156	PANC1	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.2582936373358241	[385]	[285,667,300,383]	4	hSpCas9	negative selection	8218046
45095184	45095207	20	-	27260156	PANC1	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.28452201296152896	[469]	[206,422,379,331]	-4	hSpCas9	negative selection	8282300
45099163	45099186	20	-	27260156	PANC1	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.7942788887803685	[140]	[59,12,32,28]	-9	hSpCas9	negative selection	8282301
45099154	45099177	20	+	27260156	PANC1	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.18268099994028203	[634]	[672,714,475,618]	3	hSpCas9	negative selection	8282302
45098324	45098347	20	+	27260156	PANC0813	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.8886355732163876	[419]	[871,917,1023,838]	9	hSpCas9	negative selection	8339295
45098384	45098407	20	+	27260156	PANC0813	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.21499344928558362	[939]	[1034,1271,1417,1371]	3	hSpCas9	negative selection	8339296
45094935	45094958	20	-	27260156	PANC0813	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.09966109585927244	[385]	[489,450,462,535]	1	hSpCas9	negative selection	8339297
45095184	45095207	20	-	27260156	PANC0813	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.13285412479840078	[469]	[659,485,461,423]	-2	hSpCas9	negative selection	8403551
45099163	45099186	20	-	27260156	PANC0813	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.3592921164169602	[140]	[60,73,10,108]	-9	hSpCas9	negative selection	8403552
45099154	45099177	20	+	27260156	PANC0813	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.13415445071565918	[634]	[782,967,784,737]	2	hSpCas9	negative selection	8403553
45098324	45098347	20	+	27260156	RDES	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.6955643247974602	[419]	[733,720,741,945]	9	hSpCas9	negative selection	8460546
45098384	45098407	20	+	27260156	RDES	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.11424131241046853	[939]	[728,927,1063,1369]	-2	hSpCas9	negative selection	8460547
45094935	45094958	20	-	27260156	RDES	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.07071523791571202	[385]	[297,561,563,456]	1	hSpCas9	negative selection	8460548
45095184	45095207	20	-	27260156	RDES	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.026661346379682666	[469]	[546,400,502,684]	0	hSpCas9	negative selection	8524802
45099163	45099186	20	-	27260156	RDES	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.6315347415865171	[140]	[99,84,151,78]	-8	hSpCas9	negative selection	8524803
45099154	45099177	20	+	27260156	RDES	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.2595576210948036	[634]	[619,568,643,584]	-4	hSpCas9	negative selection	8524804
45098324	45098347	20	+	27260156	PC3	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5888135628283034	[419]	[336,689,1345,489]	9	hSpCas9	negative selection	8581797
45098384	45098407	20	+	27260156	PC3	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.016389062831363654	[939]	[598,1013,1349,952]	0	hSpCas9	negative selection	8581798
45094935	45094958	20	-	27260156	PC3	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.36380071445477313	[385]	[269,638,810,426]	7	hSpCas9	negative selection	8581799
45095184	45095207	20	-	27260156	PC3	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.327354912733303	[469]	[250,363,735,295]	-6	hSpCas9	negative selection	8646053
45099163	45099186	20	-	27260156	PC3	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	0.02224004503030752	[140]	[47,63,359,225]	0	hSpCas9	negative selection	8646054
45099154	45099177	20	+	27260156	PC3	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.21043256335009647	[634]	[396,416,818,679]	-5	hSpCas9	negative selection	8646055
45098324	45098347	20	+	27260156	PATU8988T	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.7966820329741564	[419]	[549,792,847,628]	9	hSpCas9	negative selection	8703048
45098384	45098407	20	+	27260156	PATU8988T	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.13443491353553694	[939]	[1004,982,967,1033]	2	hSpCas9	negative selection	8703049
45094935	45094958	20	-	27260156	PATU8988T	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.3022674821447274	[385]	[448,382,395,617]	5	hSpCas9	negative selection	8703050
45095184	45095207	20	-	27260156	PATU8988T	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.14311428698258682	[469]	[371,343,571,342]	-2	hSpCas9	negative selection	8767304
45099163	45099186	20	-	27260156	PATU8988T	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.9704097406891121	[140]	[31,23,45,35]	-9	hSpCas9	negative selection	8767305
45099154	45099177	20	+	27260156	PATU8988T	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.16486407319424723	[634]	[532,463,598,587]	-3	hSpCas9	negative selection	8767306
45098324	45098347	20	+	27260156	T47D	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5789701439920355	[419]	[916,600,750,663]	9	hSpCas9	negative selection	8824299
45098384	45098407	20	+	27260156	T47D	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.03625823748588941	[939]	[1117,888,1104,1177]	-1	hSpCas9	negative selection	8824300
45094935	45094958	20	-	27260156	T47D	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	-0.03072995414094476	[385]	[452,383,464,463]	0	hSpCas9	negative selection	8824301
45095184	45095207	20	-	27260156	T47D	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.23201740038998564	[469]	[466,435,472,491]	-5	hSpCas9	negative selection	8888555
45099163	45099186	20	-	27260156	T47D	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.8054354761451179	[140]	[136,72,58,109]	-9	hSpCas9	negative selection	8888556
45099154	45099177	20	+	27260156	T47D	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.208418815994603	[634]	[554,553,758,699]	-4	hSpCas9	negative selection	8888557
45098324	45098347	20	+	27260156	SU8686	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.9962451182834525	[419]	[710,760,1004,873]	9	hSpCas9	negative selection	8945550
45098384	45098407	20	+	27260156	SU8686	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.10476463285548765	[939]	[837,1063,965,1169]	1	hSpCas9	negative selection	8945551
45094935	45094958	20	-	27260156	SU8686	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	-0.055259835749319475	[385]	[350,310,235,618]	-1	hSpCas9	negative selection	8945552
45095184	45095207	20	-	27260156	SU8686	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.10742211966701609	[469]	[456,331,527,420]	-2	hSpCas9	negative selection	9009806
45099163	45099186	20	-	27260156	SU8686	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-1.0758428686316204	[140]	[49,63,77,76]	-8	hSpCas9	negative selection	9009807
45099154	45099177	20	+	27260156	SU8686	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.312254331608117	[634]	[487,438,529,592]	-5	hSpCas9	negative selection	9009808
45098324	45098347	20	+	27260156	SKES1	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.5122688489145454	[419]	[607,842,525,455]	8	hSpCas9	negative selection	9066801
45098384	45098407	20	+	27260156	SKES1	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.10669120073619476	[939]	[1052,1012,808,666]	-2	hSpCas9	negative selection	9066802
45094935	45094958	20	-	27260156	SKES1	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.14315098033246126	[385]	[531,341,428,400]	3	hSpCas9	negative selection	9066803
45095184	45095207	20	-	27260156	SKES1	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.059539073639968035	[469]	[447,741,420,243]	-1	hSpCas9	negative selection	9131057
45099163	45099186	20	-	27260156	SKES1	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.7355866573452665	[140]	[122,101,44,75]	-9	hSpCas9	negative selection	9131058
45099154	45099177	20	+	27260156	SKES1	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.019469044517558542	[634]	[729,747,627,438]	0	hSpCas9	negative selection	9131059
45098324	45098347	20	+	27260156	TOV112D	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.42429459523370916	[419]	[612,697,529,455]	7	hSpCas9	negative selection	9188052
45098384	45098407	20	+	27260156	TOV112D	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.12502150132866363	[939]	[1048,964,815,667]	-2	hSpCas9	negative selection	9188053
45094935	45094958	20	-	27260156	TOV112D	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.48943766419415446	[385]	[475,576,399,714]	8	hSpCas9	negative selection	9188054
45095184	45095207	20	-	27260156	TOV112D	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.02022013303311848	[469]	[661,612,306,330]	0	hSpCas9	negative selection	9252308
45099163	45099186	20	-	27260156	TOV112D	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.7779332689607317	[140]	[72,71,99,80]	-9	hSpCas9	negative selection	9252309
45099154	45099177	20	+	27260156	TOV112D	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.07552451527042897	[634]	[524,972,377,620]	-1	hSpCas9	negative selection	9252310
45098324	45098347	20	+	27260156	TC71	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.618351385651909	[419]	[658,639,707,761]	9	hSpCas9	negative selection	9309303
45098384	45098407	20	+	27260156	TC71	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	-0.07524053423584054	[939]	[1023,889,865,1052]	-2	hSpCas9	negative selection	9309304
45094935	45094958	20	-	27260156	TC71	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.27131176929905954	[385]	[457,579,368,601]	6	hSpCas9	negative selection	9309305
45095184	45095207	20	-	27260156	TC71	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	-0.038377535474972274	[469]	[500,521,433,507]	-1	hSpCas9	negative selection	9373559
45099163	45099186	20	-	27260156	TC71	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.9946132768779161	[140]	[67,110,63,59]	-9	hSpCas9	negative selection	9373560
45099154	45099177	20	+	27260156	TC71	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	0.04781349187497319	[634]	[689,662,626,845]	1	hSpCas9	negative selection	9373561
45098324	45098347	20	+	27260156	TC32	viability	CGGCAAGCGCGTTCTCGCCTAGG	KCNS1	ENSG00000124134	0.777034050073947	[419]	[683,428,937,757]	9	hSpCas9	negative selection	9430554
45098384	45098407	20	+	27260156	TC32	viability	ACAGCTCGTCGAGCACGTGCAGG	KCNS1	ENSG00000124134	0.02114341969036726	[939]	[818,671,1164,1024]	0	hSpCas9	negative selection	9430555
45094935	45094958	20	-	27260156	TC32	viability	GACATCCCGAGAAACCTCTCAGG	KCNS1	ENSG00000124134	0.35753065562086256	[385]	[443,253,687,574]	6	hSpCas9	negative selection	9430556
45095184	45095207	20	-	27260156	TC32	viability	CACAGTGAGCATGACCACCGTGG	KCNS1	ENSG00000124134	0.009994798220067646	[469]	[421,321,500,573]	0	hSpCas9	negative selection	9494810
45099163	45099186	20	-	27260156	TC32	viability	GTGGTGCTGCCAACACCCCTAGG	KCNS1	ENSG00000124134	-0.6594767668026991	[140]	[52,62,105,126]	-8	hSpCas9	negative selection	9494811
45099154	45099177	20	+	27260156	TC32	viability	CACTTACCTCCTAGGGGTGTTGG	KCNS1	ENSG00000124134	-0.014365345353173076	[634]	[477,445,842,679]	0	hSpCas9	negative selection	9494812
45095011	45095034	20	+	27869803	HPAFII	viability after 27 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.7371964417503526	[413]	[436,300,NaN]	6	hSpCas9	negative selection	9577789
45095046	45095069	20	+	27869803	HPAFII	viability after 27 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	-0.15333954100786396	[264]	[121,127,NaN]	-1	hSpCas9	negative selection	9577790
45095046	45095069	20	-	27869803	HPAFII	viability after 27 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	-0.05891528127454898	[202]	[162,51,NaN]	0	hSpCas9	negative selection	9577791
45097844	45097867	20	+	27869803	HPAFII	viability after 27 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.9844679613425797	[362]	[138,60,NaN]	-6	hSpCas9	negative selection	9577792
45098410	45098433	20	-	27869803	HPAFII	viability after 27 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.15764608333063235	[620]	[313,405,NaN]	1	hSpCas9	negative selection	9577793
45098658	45098681	20	+	27869803	HPAFII	viability after 27 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.5351830573714236	[409]	[439,205,NaN]	4	hSpCas9	negative selection	9577794
45095011	45095034	20	+	27869803	HPAFII	viability after 15 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.17417878296222433	[413]	[678,391,NaN]	2	hSpCas9	negative selection	9660238
45095046	45095069	20	+	27869803	HPAFII	viability after 15 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	-0.010741646208741573	[264]	[360,233,NaN]	0	hSpCas9	negative selection	9660239
45095046	45095069	20	-	27869803	HPAFII	viability after 15 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	-0.037187730670688035	[202]	[404,92,NaN]	0	hSpCas9	negative selection	9660240
45097844	45097867	20	+	27869803	HPAFII	viability after 15 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.4136000379099374	[362]	[504,160,NaN]	-4	hSpCas9	negative selection	9660241
45098410	45098433	20	-	27869803	HPAFII	viability after 15 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.105896497375783	[620]	[687,577,NaN]	-1	hSpCas9	negative selection	9660242
45098658	45098681	20	+	27869803	HPAFII	viability after 15 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.30194730618699817	[409]	[645,177,NaN]	-3	hSpCas9	negative selection	9660243
45095011	45095034	20	+	27869803	ASPC1	viability after 36 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.2994899791238357	[1067]	[572,498,341]	3	hSpCas9	negative selection	9742687
45095046	45095069	20	+	27869803	ASPC1	viability after 36 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.07518745069398294	[609]	[286,246,159]	0	hSpCas9	negative selection	9742688
45095046	45095069	20	-	27869803	ASPC1	viability after 36 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	-0.6235505335117814	[417]	[56,235,7]	-6	hSpCas9	negative selection	9742689
45097844	45097867	20	+	27869803	ASPC1	viability after 36 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	0.05267339034837615	[689]	[459,120,201]	0	hSpCas9	negative selection	9742690
45098410	45098433	20	-	27869803	ASPC1	viability after 36 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.6589951432679875	[1397]	[582,791,876]	6	hSpCas9	negative selection	9742691
45098658	45098681	20	+	27869803	ASPC1	viability after 36 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	-0.25071367622729857	[1440]	[351,389,493]	-3	hSpCas9	negative selection	9742692
45095011	45095034	20	+	27869803	PATU8988S	viability after 35 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.5043744658173611	[1053]	[669,533,NaN]	5	hSpCas9	negative selection	9825136
45095046	45095069	20	+	27869803	PATU8988S	viability after 35 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.8372423894000043	[452]	[309,341,NaN]	8	hSpCas9	negative selection	9825137
45095046	45095069	20	-	27869803	PATU8988S	viability after 35 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.6182377355182997	[440]	[331,212,NaN]	6	hSpCas9	negative selection	9825138
45097844	45097867	20	+	27869803	PATU8988S	viability after 35 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	0.06023874125097922	[730]	[290,322,NaN]	0	hSpCas9	negative selection	9825139
45098410	45098433	20	-	27869803	PATU8988S	viability after 35 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.3467338761234945	[1385]	[419,457,NaN]	-4	hSpCas9	negative selection	9825140
45098658	45098681	20	+	27869803	PATU8988S	viability after 35 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.46799874967122546	[1205]	[600,742,NaN]	5	hSpCas9	negative selection	9825141
45095011	45095034	20	+	27869803	PATU8988S	viability after 31 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.2931032581160281	[1053]	[477,561,NaN]	3	hSpCas9	negative selection	9907585
45095046	45095069	20	+	27869803	PATU8988S	viability after 31 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	0.8273876699603735	[452]	[338,296,NaN]	8	hSpCas9	negative selection	9907586
45095046	45095069	20	-	27869803	PATU8988S	viability after 31 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.2964320557920075	[440]	[200,234,NaN]	3	hSpCas9	negative selection	9907587
45097844	45097867	20	+	27869803	PATU8988S	viability after 31 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.14489996194070565	[730]	[205,336,NaN]	-2	hSpCas9	negative selection	9907588
45098410	45098433	20	-	27869803	PATU8988S	viability after 31 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	-0.17884349704908553	[1385]	[412,583,NaN]	-2	hSpCas9	negative selection	9907589
45098658	45098681	20	+	27869803	PATU8988S	viability after 31 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.2966644643750931	[1205]	[547,644,NaN]	3	hSpCas9	negative selection	9907590
45095011	45095034	20	+	27869803	HPAFII	viability after 35 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	1.012387305075149	[413]	[347,506,NaN]	6	hSpCas9	negative selection	9990034
45095046	45095069	20	+	27869803	HPAFII	viability after 35 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	-0.5693325182163238	[264]	[88,91,NaN]	-3	hSpCas9	negative selection	9990035
45095046	45095069	20	-	27869803	HPAFII	viability after 35 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.322354996694907	[202]	[183,65,NaN]	2	hSpCas9	negative selection	9990036
45097844	45097867	20	+	27869803	HPAFII	viability after 35 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.4898385176189564	[362]	[207,43,NaN]	-3	hSpCas9	negative selection	9990037
45098410	45098433	20	-	27869803	HPAFII	viability after 35 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.649834566712983	[620]	[298,711,NaN]	4	hSpCas9	negative selection	9990038
45098658	45098681	20	+	27869803	HPAFII	viability after 35 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.0026643084190707267	[409]	[214,199,NaN]	0	hSpCas9	negative selection	9990039
45095011	45095034	20	+	27869803	HPAFII	viability after 31 days	TTGGTGGTTGCTGTTGCGCACGG	KCNS1	ENSG00000124134	0.601743680661626	[413]	[309,398,NaN]	4	hSpCas9	negative selection	10072483
45095046	45095069	20	+	27869803	HPAFII	viability after 31 days	CCTTCTGGCGCCGGTAGAAGTGG	KCNS1	ENSG00000124134	-0.1719271030382129	[264]	[109,155,NaN]	-1	hSpCas9	negative selection	10072484
45095046	45095069	20	-	27869803	HPAFII	viability after 31 days	CCACTTCTACCGGCGCCAGAAGG	KCNS1	ENSG00000124134	0.3615254419996785	[202]	[243,39,NaN]	2	hSpCas9	negative selection	10072485
45097844	45097867	20	+	27869803	HPAFII	viability after 31 days	TGTCGATGAGGTTGAGCGGGTGG	KCNS1	ENSG00000124134	-0.7387883636736494	[362]	[134,107,NaN]	-5	hSpCas9	negative selection	10072486
45098410	45098433	20	-	27869803	HPAFII	viability after 31 days	CTGCTGCACTTCTACCGCACTGG	KCNS1	ENSG00000124134	0.0700865233546124	[620]	[306,429,NaN]	0	hSpCas9	negative selection	10072487
45098658	45098681	20	+	27869803	HPAFII	viability after 31 days	GCCCGGGAACTCGCTCACAAAGG	KCNS1	ENSG00000124134	0.48883473089643026	[409]	[342,300,NaN]	3	hSpCas9	negative selection	10072488
45099176	45099199	20	+	28162770	P31FUJ	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.13897757774850739	[346]	[448]	1	hSpCas9	negative selection	10178174
45098480	45098503	20	-	28162770	P31FUJ	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.6141861770796554	[317]	[571]	7	hSpCas9	negative selection	10178175
45098602	45098625	20	-	28162770	P31FUJ	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	0.161112003298711	[85]	[112]	1	hSpCas9	negative selection	10178176
45098429	45098452	20	+	28162770	P31FUJ	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-0.4738103039181734	[155]	[131]	-4	hSpCas9	negative selection	10178177
45098052	45098075	20	+	28162770	P31FUJ	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.679734954335282	[101]	[191]	7	hSpCas9	negative selection	10178178
45098021	45098044	20	-	28162770	P31FUJ	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.37379230513701056	[289]	[262]	-3	hSpCas9	negative selection	10178179
45097780	45097803	20	-	28162770	P31FUJ	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	0.3758392927762882	[140]	[214]	4	hSpCas9	negative selection	10178180
45097650	45097673	20	+	28162770	P31FUJ	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	0.5152185782608233	[77]	[130]	6	hSpCas9	negative selection	10178181
45099160	45099183	20	-	28162770	P31FUJ	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.18085012477965684	[299]	[310]	-2	hSpCas9	negative selection	10178182
45098589	45098612	20	-	28162770	P31FUJ	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	1.6251787907131936	[15]	[57]	9	hSpCas9	negative selection	10178183
45099176	45099199	20	+	28162770	TF1	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	NaN	[NaN]	[308]	1	hSpCas9	negative selection	10347540
45098480	45098503	20	-	28162770	TF1	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	NaN	[NaN]	[533]	1	hSpCas9	negative selection	10347541
45098602	45098625	20	-	28162770	TF1	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	NaN	[NaN]	[166]	1	hSpCas9	negative selection	10347542
45098429	45098452	20	+	28162770	TF1	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10347543
45098052	45098075	20	+	28162770	TF1	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	NaN	[NaN]	[38]	1	hSpCas9	negative selection	10347544
45098021	45098044	20	-	28162770	TF1	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	NaN	[NaN]	[332]	1	hSpCas9	negative selection	10347545
45097780	45097803	20	-	28162770	TF1	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	NaN	[NaN]	[115]	1	hSpCas9	negative selection	10347546
45097650	45097673	20	+	28162770	TF1	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	NaN	[NaN]	[76]	1	hSpCas9	negative selection	10347547
45099160	45099183	20	-	28162770	TF1	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	NaN	[NaN]	[435]	1	hSpCas9	negative selection	10347548
45098589	45098612	20	-	28162770	TF1	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	NaN	[NaN]	[21]	1	hSpCas9	negative selection	10347549
45099176	45099199	20	+	28162770	SKM1	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.42126945299035834	[97]	[231]	4	hSpCas9	negative selection	10516906
45098480	45098503	20	-	28162770	SKM1	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.37281447896201747	[82]	[189]	3	hSpCas9	negative selection	10516907
45098602	45098625	20	-	28162770	SKM1	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	1.4117954865866917	[26]	[126]	9	hSpCas9	negative selection	10516908
45098429	45098452	20	+	28162770	SKM1	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	0.03713576613814479	[42]	[77]	0	hSpCas9	negative selection	10516909
45098052	45098075	20	+	28162770	SKM1	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.14628944225065643	[22]	[44]	1	hSpCas9	negative selection	10516910
45098021	45098044	20	-	28162770	SKM1	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.43042317156715076	[92]	[121]	-4	hSpCas9	negative selection	10516911
45097780	45097803	20	-	28162770	SKM1	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10516912
45097650	45097673	20	+	28162770	SKM1	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-0.21793037435314488	[24]	[37]	-2	hSpCas9	negative selection	10516913
45099160	45099183	20	-	28162770	SKM1	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.33974937197460653	[58]	[131]	3	hSpCas9	negative selection	10516914
45098589	45098612	20	-	28162770	SKM1	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.4594316186372973	[6]	[8]	-4	hSpCas9	negative selection	10516915
45099176	45099199	20	+	28162770	SKM1	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.42126945299035834	[97]	[231]	4	hSpCas9	negative selection	10686272
45098480	45098503	20	-	28162770	SKM1	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.37281447896201747	[82]	[189]	3	hSpCas9	negative selection	10686273
45098602	45098625	20	-	28162770	SKM1	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	1.4117954865866917	[26]	[126]	9	hSpCas9	negative selection	10686274
45098429	45098452	20	+	28162770	SKM1	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	0.03713576613814479	[42]	[77]	0	hSpCas9	negative selection	10686275
45098052	45098075	20	+	28162770	SKM1	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.14628944225065643	[22]	[44]	1	hSpCas9	negative selection	10686276
45098021	45098044	20	-	28162770	SKM1	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.43042317156715076	[92]	[121]	-4	hSpCas9	negative selection	10686277
45097780	45097803	20	-	28162770	SKM1	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-1.0850361038557992	[29]	[24]	-7	hSpCas9	negative selection	10686278
45097650	45097673	20	+	28162770	SKM1	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-0.21793037435314488	[24]	[37]	-2	hSpCas9	negative selection	10686279
45099160	45099183	20	-	28162770	SKM1	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.33974937197460653	[58]	[131]	3	hSpCas9	negative selection	10686280
45098589	45098612	20	-	28162770	SKM1	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.4594316186372973	[6]	[8]	-4	hSpCas9	negative selection	10686281
45099176	45099199	20	+	28162770	PL21	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	-0.08674153329884149	[365]	[149]	0	hSpCas9	negative selection	10855638
45098480	45098503	20	-	28162770	PL21	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.7769281837647763	[235]	[175]	6	hSpCas9	negative selection	10855639
45098602	45098625	20	-	28162770	PL21	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-0.11633405030593413	[131]	[52]	-1	hSpCas9	negative selection	10855640
45098429	45098452	20	+	28162770	PL21	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-1.3657140632841314	[224]	[37]	-7	hSpCas9	negative selection	10855641
45098052	45098075	20	+	28162770	PL21	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.12613903304554341	[79]	[37]	1	hSpCas9	negative selection	10855642
45098021	45098044	20	-	28162770	PL21	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.6116711702666284	[205]	[136]	5	hSpCas9	negative selection	10855643
45097780	45097803	20	-	28162770	PL21	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-0.3463487384172005	[110]	[37]	-2	hSpCas9	negative selection	10855644
45097650	45097673	20	+	28162770	PL21	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	1.7285185868441089	[51]	[74]	9	hSpCas9	negative selection	10855645
45099160	45099183	20	-	28162770	PL21	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.13614377337511227	[201]	[79]	-1	hSpCas9	negative selection	10855646
45098589	45098612	20	-	28162770	PL21	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-3.3848228862318366	[23]	[0]	-9	hSpCas9	negative selection	10855647
45099176	45099199	20	+	28162770	P31FUJ	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.13897757774850739	[346]	[448]	1	hSpCas9	negative selection	11025004
45098480	45098503	20	-	28162770	P31FUJ	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.6141861770796554	[317]	[571]	7	hSpCas9	negative selection	11025005
45098602	45098625	20	-	28162770	P31FUJ	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	0.161112003298711	[85]	[112]	1	hSpCas9	negative selection	11025006
45098429	45098452	20	+	28162770	P31FUJ	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-0.4738103039181734	[155]	[131]	-4	hSpCas9	negative selection	11025007
45098052	45098075	20	+	28162770	P31FUJ	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.679734954335282	[101]	[191]	7	hSpCas9	negative selection	11025008
45098021	45098044	20	-	28162770	P31FUJ	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.37379230513701056	[289]	[262]	-3	hSpCas9	negative selection	11025009
45097780	45097803	20	-	28162770	P31FUJ	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	0.3758392927762882	[140]	[214]	4	hSpCas9	negative selection	11025010
45097650	45097673	20	+	28162770	P31FUJ	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	0.5152185782608233	[77]	[130]	6	hSpCas9	negative selection	11025011
45099160	45099183	20	-	28162770	P31FUJ	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.18085012477965684	[299]	[310]	-2	hSpCas9	negative selection	11025012
45098589	45098612	20	-	28162770	P31FUJ	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	1.6251787907131936	[15]	[57]	9	hSpCas9	negative selection	11025013
45099176	45099199	20	+	28162770	OCIAML5	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.5441937213842186	[173]	[457]	5	hSpCas9	negative selection	11194370
45098480	45098503	20	-	28162770	OCIAML5	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.9221662810188985	[213]	[731]	7	hSpCas9	negative selection	11194371
45098602	45098625	20	-	28162770	OCIAML5	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-1.0897581285833273	[78]	[66]	-6	hSpCas9	negative selection	11194372
45098429	45098452	20	+	28162770	OCIAML5	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-1.5790480764575812	[95]	[57]	-7	hSpCas9	negative selection	11194373
45098052	45098075	20	+	28162770	OCIAML5	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	-0.40626681781446616	[57]	[78]	-3	hSpCas9	negative selection	11194374
45098021	45098044	20	-	28162770	OCIAML5	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.3922406269008917	[83]	[198]	3	hSpCas9	negative selection	11194375
45097780	45097803	20	-	28162770	OCIAML5	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-2.416851189647523	[70]	[23]	-8	hSpCas9	negative selection	11194376
45097650	45097673	20	+	28162770	OCIAML5	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	1.0865328844718596	[35]	[137]	8	hSpCas9	negative selection	11194377
45099160	45099183	20	-	28162770	OCIAML5	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.01699089124794273	[161]	[288]	0	hSpCas9	negative selection	11194378
45098589	45098612	20	-	28162770	OCIAML5	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	0.6073650477733001	[7]	[21]	5	hSpCas9	negative selection	11194379
45099176	45099199	20	+	28162770	EOL1	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.06644083737074347	[715]	[394]	0	hSpCas9	negative selection	11363736
45098480	45098503	20	-	28162770	EOL1	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.8929546468752179	[276]	[270]	7	hSpCas9	negative selection	11363737
45098602	45098625	20	-	28162770	EOL1	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-0.19963163965019526	[193]	[88]	-1	hSpCas9	negative selection	11363738
45098429	45098452	20	+	28162770	EOL1	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	0.08524182527962906	[330]	[184]	0	hSpCas9	negative selection	11363739
45098052	45098075	20	+	28162770	EOL1	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.7915223529397513	[192]	[175]	7	hSpCas9	negative selection	11363740
45098021	45098044	20	-	28162770	EOL1	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.7990168894866756	[455]	[417]	7	hSpCas9	negative selection	11363741
45097780	45097803	20	-	28162770	EOL1	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-2.229257564508501	[88]	[9]	-8	hSpCas9	negative selection	11363742
45097650	45097673	20	+	28162770	EOL1	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	0.5412191320190287	[59]	[45]	5	hSpCas9	negative selection	11363743
45099160	45099183	20	-	28162770	EOL1	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-1.3484707228358814	[231]	[47]	-7	hSpCas9	negative selection	11363744
45098589	45098612	20	-	28162770	EOL1	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	0.8505471901267581	[19]	[18]	7	hSpCas9	negative selection	11363745
45099176	45099199	20	+	28162770	MOLM13	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.6276251621743546	[520]	[581]	5	hSpCas9	negative selection	11533102
45098480	45098503	20	-	28162770	MOLM13	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	-0.24996738967392285	[374]	[227]	-1	hSpCas9	negative selection	11533103
45098602	45098625	20	-	28162770	MOLM13	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-0.838097169473762	[224]	[90]	-4	hSpCas9	negative selection	11533104
45098429	45098452	20	+	28162770	MOLM13	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-2.1232253461581725	[234]	[38]	-7	hSpCas9	negative selection	11533105
45098052	45098075	20	+	28162770	MOLM13	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	1.6902818028810267	[98]	[230]	9	hSpCas9	negative selection	11533106
45098021	45098044	20	-	28162770	MOLM13	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.3911832080624521	[308]	[292]	3	hSpCas9	negative selection	11533107
45097780	45097803	20	-	28162770	MOLM13	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-0.49430858574303693	[112]	[57]	-3	hSpCas9	negative selection	11533108
45097650	45097673	20	+	28162770	MOLM13	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	0.10531930215987062	[62]	[48]	0	hSpCas9	negative selection	11533109
45099160	45099183	20	-	28162770	MOLM13	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.5558007245005216	[306]	[150]	-3	hSpCas9	negative selection	11533110
45098589	45098612	20	-	28162770	MOLM13	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-3.532110618455422	[31]	[1]	-8	hSpCas9	negative selection	11533111
45099176	45099199	20	+	28162770	HEL	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.5289569085955785	[566]	[523]	4	hSpCas9	negative selection	11702468
45098480	45098503	20	-	28162770	HEL	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.32410581667457566	[327]	[262]	2	hSpCas9	negative selection	11702469
45098602	45098625	20	-	28162770	HEL	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-0.07269360061620778	[132]	[80]	0	hSpCas9	negative selection	11702470
45098429	45098452	20	+	28162770	HEL	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	0.06076637388501243	[240]	[160]	0	hSpCas9	negative selection	11702471
45098052	45098075	20	+	28162770	HEL	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	-0.8555120355274686	[112]	[39]	-5	hSpCas9	negative selection	11702472
45098021	45098044	20	-	28162770	HEL	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.8414228264240933	[297]	[341]	7	hSpCas9	negative selection	11702473
45097780	45097803	20	-	28162770	HEL	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-1.780472598724187	[117]	[21]	-7	hSpCas9	negative selection	11702474
45097650	45097673	20	+	28162770	HEL	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	0.689281417937387	[60]	[62]	6	hSpCas9	negative selection	11702475
45099160	45099183	20	-	28162770	HEL	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.03130411991800984	[219]	[143]	0	hSpCas9	negative selection	11702476
45098589	45098612	20	-	28162770	HEL	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.17668892235782208	[29]	[16]	-1	hSpCas9	negative selection	11702477
45099176	45099199	20	+	28162770	MV411	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.026937188787536037	[380]	[326]	0	hSpCas9	negative selection	11871834
45098480	45098503	20	-	28162770	MV411	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.6198831733371511	[274]	[355]	5	hSpCas9	negative selection	11871835
45098602	45098625	20	-	28162770	MV411	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	0.42660639646870757	[120]	[136]	4	hSpCas9	negative selection	11871836
45098429	45098452	20	+	28162770	MV411	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-0.9322684714521225	[221]	[97]	-6	hSpCas9	negative selection	11871837
45098052	45098075	20	+	28162770	MV411	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	-1.1757738799417685	[117]	[43]	-6	hSpCas9	negative selection	11871838
45098021	45098044	20	-	28162770	MV411	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	0.4767163577044631	[208]	[244]	4	hSpCas9	negative selection	11871839
45097780	45097803	20	-	28162770	MV411	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-0.2847834878664076	[93]	[64]	-2	hSpCas9	negative selection	11871840
45097650	45097673	20	+	28162770	MV411	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-1.6352054985790658	[58]	[15]	-7	hSpCas9	negative selection	11871841
45099160	45099183	20	-	28162770	MV411	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.3706693167770462	[156]	[170]	3	hSpCas9	negative selection	11871842
45098589	45098612	20	-	28162770	MV411	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.46305583202223977	[17]	[10]	-3	hSpCas9	negative selection	11871843
45099176	45099199	20	+	28162770	MONOMAC1	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	-0.3575015192527997	[227]	[203]	-3	hSpCas9	negative selection	12041200
45098480	45098503	20	-	28162770	MONOMAC1	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.784815806230187	[159]	[315]	7	hSpCas9	negative selection	12041201
45098602	45098625	20	-	28162770	MONOMAC1	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	-0.006705634955404216	[77]	[88]	0	hSpCas9	negative selection	12041202
45098429	45098452	20	+	28162770	MONOMAC1	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	0.6648322340769539	[114]	[208]	6	hSpCas9	negative selection	12041203
45098052	45098075	20	+	28162770	MONOMAC1	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	-1.426518693182321	[67]	[28]	-8	hSpCas9	negative selection	12041204
45098021	45098044	20	-	28162770	MONOMAC1	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.6311326821540822	[126]	[93]	-5	hSpCas9	negative selection	12041205
45097780	45097803	20	-	28162770	MONOMAC1	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-1.1356363023954106	[68]	[35]	-7	hSpCas9	negative selection	12041206
45097650	45097673	20	+	28162770	MONOMAC1	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	0.04397125244424105	[21]	[25]	0	hSpCas9	negative selection	12041207
45099160	45099183	20	-	28162770	MONOMAC1	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.014467258134158112	[132]	[153]	0	hSpCas9	negative selection	12041208
45098589	45098612	20	-	28162770	MONOMAC1	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.366961848501866	[8]	[7]	-3	hSpCas9	negative selection	12041209
45099176	45099199	20	+	28162770	OCIAML2	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.09595414616414022	[78]	[467]	0	hSpCas9	negative selection	12210566
45098480	45098503	20	-	28162770	OCIAML2	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.6274022577183656	[47]	[410]	6	hSpCas9	negative selection	12210567
45098602	45098625	20	-	28162770	OCIAML2	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	0.34433828092531793	[26]	[189]	3	hSpCas9	negative selection	12210568
45098429	45098452	20	+	28162770	OCIAML2	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-0.536863523642248	[38]	[148]	-4	hSpCas9	negative selection	12210569
45098052	45098075	20	+	28162770	OCIAML2	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	0.8023886691642549	[14]	[144]	7	hSpCas9	negative selection	12210570
45098021	45098044	20	-	28162770	OCIAML2	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.18732302438210624	[52]	[257]	-1	hSpCas9	negative selection	12210571
45097780	45097803	20	-	28162770	OCIAML2	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	-0.7643610282988716	[18]	[61]	-5	hSpCas9	negative selection	12210572
45097650	45097673	20	+	28162770	OCIAML2	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	0.6448473921777749	[8]	[77]	6	hSpCas9	negative selection	12210573
45099160	45099183	20	-	28162770	OCIAML2	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	-0.11514917064377225	[33]	[173]	-1	hSpCas9	negative selection	12210574
45098589	45098612	20	-	28162770	OCIAML2	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.33312630149222633	[4]	[21]	-3	hSpCas9	negative selection	12210575
45099176	45099199	20	+	28162770	OCIAML3	viability	GCAGCACCACTTTAGACCGGAGG	KCNS1	ENSG00000124134	0.8026513296398261	[78]	[415]	7	hSpCas9	negative selection	12379932
45098480	45098503	20	-	28162770	OCIAML3	viability	CCTGTGCGACGACTACGACGAGG	KCNS1	ENSG00000124134	0.13276218673615459	[70]	[234]	1	hSpCas9	negative selection	12379933
45098602	45098625	20	-	28162770	OCIAML3	viability	GAGGCGCTGCGCGTGAACGTGGG	KCNS1	ENSG00000124134	0.7868141436167676	[23]	[124]	7	hSpCas9	negative selection	12379934
45098429	45098452	20	+	28162770	OCIAML3	viability	GCAGGCTCAGGAAGAAGCCCGGG	KCNS1	ENSG00000124134	-0.5268934444656261	[62]	[131]	-4	hSpCas9	negative selection	12379935
45098052	45098075	20	+	28162770	OCIAML3	viability	GTGGATGCACATGGCGGCGATGG	KCNS1	ENSG00000124134	-0.20496534957826396	[20]	[54]	-2	hSpCas9	negative selection	12379936
45098021	45098044	20	-	28162770	OCIAML3	viability	CGAGTACCAGGCCCGCGAGGCGG	KCNS1	ENSG00000124134	-0.10215454399448837	[63]	[179]	-1	hSpCas9	negative selection	12379937
45097780	45097803	20	-	28162770	OCIAML3	viability	GTGGCACTGGGCGACCAGGGCGG	KCNS1	ENSG00000124134	0.02892271059601348	[24]	[76]	0	hSpCas9	negative selection	12379938
45097650	45097673	20	+	28162770	OCIAML3	viability	CAGAGGCCGTACCTTGAGCGTGG	KCNS1	ENSG00000124134	-0.5940076403241632	[25]	[51]	-4	hSpCas9	negative selection	12379939
45099160	45099183	20	-	28162770	OCIAML3	viability	GTGCTGCCAACACCCCTAGGAGG	KCNS1	ENSG00000124134	0.8978454560055116	[47]	[269]	7	hSpCas9	negative selection	12379940
45098589	45098612	20	-	28162770	OCIAML3	viability	TGAACGTGGGTGGCGTGCGGCGG	KCNS1	ENSG00000124134	-0.3716152189877153	[5]	[13]	-3	hSpCas9	negative selection	12379941