114096151 |
114096174 |
9 |
+ |
26472758 |
Jiyoye |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.7250338120841889 |
[141] |
[176] |
5 |
hSpCas9 |
negative selection |
83008 |
114092393 |
114092416 |
9 |
- |
26472758 |
Jiyoye |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
0.7620180988659708 |
[103] |
[132] |
5 |
hSpCas9 |
negative selection |
83009 |
114097670 |
114097693 |
9 |
+ |
26472758 |
Jiyoye |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
-0.08522100047921011 |
[82] |
[58] |
0 |
hSpCas9 |
negative selection |
83010 |
114096101 |
114096124 |
9 |
- |
26472758 |
Jiyoye |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
0.6609319737516565 |
[77] |
[92] |
5 |
hSpCas9 |
negative selection |
83011 |
114095082 |
114095105 |
9 |
+ |
26472758 |
Jiyoye |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.5006022454741423 |
[283] |
[302] |
4 |
hSpCas9 |
negative selection |
83012 |
114094398 |
114094421 |
9 |
- |
26472758 |
Jiyoye |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.3617324107447064 |
[128] |
[124] |
2 |
hSpCas9 |
negative selection |
83013 |
114094371 |
114094394 |
9 |
+ |
26472758 |
Jiyoye |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
4.314065977114391 |
[0] |
[14] |
9 |
hSpCas9 |
negative selection |
83014 |
114093426 |
114093449 |
9 |
+ |
26472758 |
Jiyoye |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
-0.23749336533955054 |
[110] |
[70] |
-2 |
hSpCas9 |
negative selection |
83015 |
114093305 |
114093328 |
9 |
+ |
26472758 |
Jiyoye |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-2.5928246184941264 |
[159] |
[19] |
-9 |
hSpCas9 |
negative selection |
83016 |
114093292 |
114093315 |
9 |
+ |
26472758 |
Jiyoye |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
1.8852226783105175 |
[27] |
[77] |
8 |
hSpCas9 |
negative selection |
83017 |
114096151 |
114096174 |
9 |
+ |
26472758 |
KBM7 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.06329107654110967 |
[465,533] |
[294,206] |
0 |
hSpCas9 |
negative selection |
274126 |
114092393 |
114092416 |
9 |
- |
26472758 |
KBM7 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
0.5897764410290547 |
[585,505] |
[170,576] |
6 |
hSpCas9 |
negative selection |
274127 |
114097670 |
114097693 |
9 |
+ |
26472758 |
KBM7 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.6109434538514245 |
[295,265] |
[207,195] |
6 |
hSpCas9 |
negative selection |
274128 |
114096101 |
114096124 |
9 |
- |
26472758 |
KBM7 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
0.9128695414429234 |
[239,210] |
[259,144] |
8 |
hSpCas9 |
negative selection |
274129 |
114095082 |
114095105 |
9 |
+ |
26472758 |
KBM7 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.3260198092479849 |
[1204,1278] |
[910,582] |
3 |
hSpCas9 |
negative selection |
274130 |
114094398 |
114094421 |
9 |
- |
26472758 |
KBM7 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.28577056406375273 |
[641,398] |
[279,303] |
3 |
hSpCas9 |
negative selection |
274131 |
114094371 |
114094394 |
9 |
+ |
26472758 |
KBM7 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-0.7005877987820952 |
[45,69] |
[31,3] |
-5 |
hSpCas9 |
negative selection |
274132 |
114093426 |
114093449 |
9 |
+ |
26472758 |
KBM7 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.7259454598999326 |
[282,347] |
[255,242] |
7 |
hSpCas9 |
negative selection |
274133 |
114093305 |
114093328 |
9 |
+ |
26472758 |
KBM7 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.244819410030153 |
[473,269] |
[41,98] |
-7 |
hSpCas9 |
negative selection |
274134 |
114093292 |
114093315 |
9 |
+ |
26472758 |
KBM7 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-0.12229921455136838 |
[456,308] |
[219,111] |
-1 |
hSpCas9 |
negative selection |
274135 |
114096151 |
114096174 |
9 |
+ |
26472758 |
Raji |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.43644781154259055 |
[241] |
[75] |
4 |
hSpCas9 |
negative selection |
465244 |
114092393 |
114092416 |
9 |
- |
26472758 |
Raji |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
-0.29116584111667526 |
[289] |
[54] |
-2 |
hSpCas9 |
negative selection |
465245 |
114097670 |
114097693 |
9 |
+ |
26472758 |
Raji |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.0663562671135447 |
[106] |
[25] |
0 |
hSpCas9 |
negative selection |
465246 |
114096101 |
114096124 |
9 |
- |
26472758 |
Raji |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.2350086620734786 |
[70] |
[13] |
-2 |
hSpCas9 |
negative selection |
465247 |
114095082 |
114095105 |
9 |
+ |
26472758 |
Raji |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.46917901337546375 |
[413] |
[132] |
4 |
hSpCas9 |
negative selection |
465248 |
114094398 |
114094421 |
9 |
- |
26472758 |
Raji |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
-0.3429744996382359 |
[316] |
[57] |
-3 |
hSpCas9 |
negative selection |
465249 |
114094371 |
114094394 |
9 |
+ |
26472758 |
Raji |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
3.3297759567100473 |
[2] |
[6] |
9 |
hSpCas9 |
negative selection |
465250 |
114093426 |
114093449 |
9 |
+ |
26472758 |
Raji |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.8887432488982592 |
[127] |
[54] |
7 |
hSpCas9 |
negative selection |
465251 |
114093305 |
114093328 |
9 |
+ |
26472758 |
Raji |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.7422821915419688 |
[172] |
[11] |
-8 |
hSpCas9 |
negative selection |
465252 |
114093292 |
114093315 |
9 |
+ |
26472758 |
Raji |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
0.09455949501601568 |
[112] |
[27] |
0 |
hSpCas9 |
negative selection |
465253 |
114096151 |
114096174 |
9 |
+ |
26472758 |
K562 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.734166621461634 |
[380] |
[534] |
6 |
hSpCas9 |
negative selection |
656362 |
114092393 |
114092416 |
9 |
- |
26472758 |
K562 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
0.29388740393074664 |
[515] |
[533] |
2 |
hSpCas9 |
negative selection |
656363 |
114097670 |
114097693 |
9 |
+ |
26472758 |
K562 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.2923134177707583 |
[236] |
[244] |
2 |
hSpCas9 |
negative selection |
656364 |
114096101 |
114096124 |
9 |
- |
26472758 |
K562 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.2620417993759918 |
[151] |
[106] |
-2 |
hSpCas9 |
negative selection |
656365 |
114095082 |
114095105 |
9 |
+ |
26472758 |
K562 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.2000246083079935 |
[824] |
[799] |
1 |
hSpCas9 |
negative selection |
656366 |
114094398 |
114094421 |
9 |
- |
26472758 |
K562 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
-0.5457888877767387 |
[459] |
[265] |
-3 |
hSpCas9 |
negative selection |
656367 |
114094371 |
114094394 |
9 |
+ |
26472758 |
K562 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
1.765250890967887 |
[22] |
[65] |
9 |
hSpCas9 |
negative selection |
656368 |
114093426 |
114093449 |
9 |
+ |
26472758 |
K562 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.13957636180894883 |
[213] |
[198] |
1 |
hSpCas9 |
negative selection |
656369 |
114093305 |
114093328 |
9 |
+ |
26472758 |
K562 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-4.409891819745444 |
[276] |
[10] |
-9 |
hSpCas9 |
negative selection |
656370 |
114093292 |
114093315 |
9 |
+ |
26472758 |
K562 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
1.2016690802071097 |
[273] |
[531] |
8 |
hSpCas9 |
negative selection |
656371 |
114095049 |
114095072 |
9 |
- |
26627737 |
DLD1 |
viability |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.5864220147733998 |
[207] |
[53,52,25] |
-5 |
hSpCas9 |
negative selection |
840925 |
114095225 |
114095248 |
9 |
- |
26627737 |
DLD1 |
viability |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.33914937511972365 |
[362] |
[83,110,76] |
-4 |
hSpCas9 |
negative selection |
840926 |
114096151 |
114096174 |
9 |
+ |
26627737 |
DLD1 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.2877008415872253 |
[1599] |
[769,407,639] |
3 |
hSpCas9 |
negative selection |
840927 |
114096419 |
114096442 |
9 |
+ |
26627737 |
DLD1 |
viability |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.14536039418675406 |
[185] |
[79,40,69] |
1 |
hSpCas9 |
negative selection |
840928 |
114097375 |
114097398 |
9 |
+ |
26627737 |
DLD1 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.9198355622707008 |
[1226] |
[512,861,796] |
8 |
hSpCas9 |
negative selection |
840929 |
114097622 |
114097645 |
9 |
+ |
26627737 |
DLD1 |
viability |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.6064908284328767 |
[745] |
[394,299,365] |
6 |
hSpCas9 |
negative selection |
840930 |
114095049 |
114095072 |
9 |
- |
26627737 |
GBM cells |
viability after 5 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-1.3669801850873493 |
[100] |
[30,10] |
-9 |
hSpCas9 |
negative selection |
923240 |
114095225 |
114095248 |
9 |
- |
26627737 |
GBM cells |
viability after 5 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.49300738735897043 |
[209] |
[158,157] |
7 |
hSpCas9 |
negative selection |
923241 |
114096151 |
114096174 |
9 |
+ |
26627737 |
GBM cells |
viability after 5 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.09534169508787893 |
[856] |
[435,545] |
1 |
hSpCas9 |
negative selection |
923242 |
114096419 |
114096442 |
9 |
+ |
26627737 |
GBM cells |
viability after 5 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.6765214535492377 |
[111] |
[78,112] |
8 |
hSpCas9 |
negative selection |
923243 |
114097375 |
114097398 |
9 |
+ |
26627737 |
GBM cells |
viability after 5 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.14551793622206888 |
[573] |
[322,357] |
2 |
hSpCas9 |
negative selection |
923244 |
114097622 |
114097645 |
9 |
+ |
26627737 |
GBM cells |
viability after 5 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.17770546639504992 |
[515] |
[283,341] |
3 |
hSpCas9 |
negative selection |
923245 |
114095049 |
114095072 |
9 |
- |
26627737 |
GBM cells |
viability after 13 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-1.016905518523949 |
[100] |
[52,5] |
-8 |
hSpCas9 |
negative selection |
1005555 |
114095225 |
114095248 |
9 |
- |
26627737 |
GBM cells |
viability after 13 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.47183975873493816 |
[209] |
[205,118] |
6 |
hSpCas9 |
negative selection |
1005556 |
114096151 |
114096174 |
9 |
+ |
26627737 |
GBM cells |
viability after 13 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.018895292527379315 |
[856] |
[576,384] |
0 |
hSpCas9 |
negative selection |
1005557 |
114096419 |
114096442 |
9 |
+ |
26627737 |
GBM cells |
viability after 13 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.829144506566466 |
[111] |
[102,111] |
8 |
hSpCas9 |
negative selection |
1005558 |
114097375 |
114097398 |
9 |
+ |
26627737 |
GBM cells |
viability after 13 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.3229208095893896 |
[573] |
[495,302] |
4 |
hSpCas9 |
negative selection |
1005559 |
114097622 |
114097645 |
9 |
+ |
26627737 |
GBM cells |
viability after 13 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.02811402978118349 |
[515] |
[305,248] |
0 |
hSpCas9 |
negative selection |
1005560 |
114095049 |
114095072 |
9 |
- |
26627737 |
GBM cells |
viability after 21 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.846190084389955 |
[100] |
[29,30] |
-6 |
hSpCas9 |
negative selection |
1087870 |
114095225 |
114095248 |
9 |
- |
26627737 |
GBM cells |
viability after 21 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.7360121166757277 |
[209] |
[212,168] |
7 |
hSpCas9 |
negative selection |
1087871 |
114096151 |
114096174 |
9 |
+ |
26627737 |
GBM cells |
viability after 21 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.13933435723453735 |
[856] |
[540,486] |
1 |
hSpCas9 |
negative selection |
1087872 |
114096419 |
114096442 |
9 |
+ |
26627737 |
GBM cells |
viability after 21 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.28557740269065834 |
[111] |
[81,66] |
3 |
hSpCas9 |
negative selection |
1087873 |
114097375 |
114097398 |
9 |
+ |
26627737 |
GBM cells |
viability after 21 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.12759040702186586 |
[573] |
[359,322] |
1 |
hSpCas9 |
negative selection |
1087874 |
114097622 |
114097645 |
9 |
+ |
26627737 |
GBM cells |
viability after 21 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.2640878905720103 |
[515] |
[344,328] |
2 |
hSpCas9 |
negative selection |
1087875 |
114095049 |
114095072 |
9 |
- |
26627737 |
RPE1 |
viability after 9 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.8517352772901181 |
[384] |
[23,121] |
-6 |
hSpCas9 |
negative selection |
1170185 |
114095225 |
114095248 |
9 |
- |
26627737 |
RPE1 |
viability after 9 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.9208564373891124 |
[1233] |
[200,207] |
-6 |
hSpCas9 |
negative selection |
1170186 |
114096151 |
114096174 |
9 |
+ |
26627737 |
RPE1 |
viability after 9 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.3055059265077482 |
[2198] |
[708,360] |
-2 |
hSpCas9 |
negative selection |
1170187 |
114096419 |
114096442 |
9 |
+ |
26627737 |
RPE1 |
viability after 9 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
1.5401723257370459 |
[295] |
[210,344] |
8 |
hSpCas9 |
negative selection |
1170188 |
114097375 |
114097398 |
9 |
+ |
26627737 |
RPE1 |
viability after 9 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.7273997878073151 |
[1885] |
[581,1487] |
5 |
hSpCas9 |
negative selection |
1170189 |
114097622 |
114097645 |
9 |
+ |
26627737 |
RPE1 |
viability after 9 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.6970132580648483 |
[1268] |
[454,887] |
4 |
hSpCas9 |
negative selection |
1170190 |
114095049 |
114095072 |
9 |
- |
26627737 |
RPE1 |
viability after 12 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
0.003867592029020539 |
[384] |
[110,95] |
0 |
hSpCas9 |
negative selection |
1252500 |
114095225 |
114095248 |
9 |
- |
26627737 |
RPE1 |
viability after 12 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-1.0552150582115942 |
[1233] |
[177,139] |
-6 |
hSpCas9 |
negative selection |
1252501 |
114096151 |
114096174 |
9 |
+ |
26627737 |
RPE1 |
viability after 12 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.10323266876980819 |
[2198] |
[685,405] |
0 |
hSpCas9 |
negative selection |
1252502 |
114096419 |
114096442 |
9 |
+ |
26627737 |
RPE1 |
viability after 12 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
1.2275886658377857 |
[295] |
[176,195] |
7 |
hSpCas9 |
negative selection |
1252503 |
114097375 |
114097398 |
9 |
+ |
26627737 |
RPE1 |
viability after 12 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.7175164801513256 |
[1885] |
[873,789] |
4 |
hSpCas9 |
negative selection |
1252504 |
114097622 |
114097645 |
9 |
+ |
26627737 |
RPE1 |
viability after 12 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.7607760660099343 |
[1268] |
[498,660] |
5 |
hSpCas9 |
negative selection |
1252505 |
114095049 |
114095072 |
9 |
- |
26627737 |
RPE1 |
viability after 15 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-1.4294548506184859 |
[384] |
[15,63] |
-7 |
hSpCas9 |
negative selection |
1334815 |
114095225 |
114095248 |
9 |
- |
26627737 |
RPE1 |
viability after 15 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-1.0458611575153276 |
[1233] |
[192,145] |
-6 |
hSpCas9 |
negative selection |
1334816 |
114096151 |
114096174 |
9 |
+ |
26627737 |
RPE1 |
viability after 15 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.3890120971613791 |
[2198] |
[1344,302] |
2 |
hSpCas9 |
negative selection |
1334817 |
114096419 |
114096442 |
9 |
+ |
26627737 |
RPE1 |
viability after 15 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
1.6108540313213793 |
[295] |
[241,268] |
8 |
hSpCas9 |
negative selection |
1334818 |
114097375 |
114097398 |
9 |
+ |
26627737 |
RPE1 |
viability after 15 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.8387882623765126 |
[1885] |
[773,1127] |
5 |
hSpCas9 |
negative selection |
1334819 |
114097622 |
114097645 |
9 |
+ |
26627737 |
RPE1 |
viability after 15 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.7183365937620096 |
[1268] |
[499,677] |
4 |
hSpCas9 |
negative selection |
1334820 |
114095049 |
114095072 |
9 |
- |
26627737 |
RPE1 |
viability after 18 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.1516035638885831 |
[384] |
[79,107] |
-1 |
hSpCas9 |
negative selection |
1417130 |
114095225 |
114095248 |
9 |
- |
26627737 |
RPE1 |
viability after 18 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-1.377696723466325 |
[1233] |
[88,169] |
-7 |
hSpCas9 |
negative selection |
1417131 |
114096151 |
114096174 |
9 |
+ |
26627737 |
RPE1 |
viability after 18 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.5825605821120232 |
[2198] |
[1301,446] |
3 |
hSpCas9 |
negative selection |
1417132 |
114096419 |
114096442 |
9 |
+ |
26627737 |
RPE1 |
viability after 18 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.8319348483263077 |
[295] |
[74,213] |
5 |
hSpCas9 |
negative selection |
1417133 |
114097375 |
114097398 |
9 |
+ |
26627737 |
RPE1 |
viability after 18 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.5756633314703907 |
[1885] |
[628,896] |
3 |
hSpCas9 |
negative selection |
1417134 |
114097622 |
114097645 |
9 |
+ |
26627737 |
RPE1 |
viability after 18 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.1294062966296865 |
[1268] |
[260,495] |
0 |
hSpCas9 |
negative selection |
1417135 |
114095049 |
114095072 |
9 |
- |
26627737 |
HeLa |
viability after 8 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.28656097807817016 |
[279] |
[104,98,96] |
-3 |
hSpCas9 |
negative selection |
1499445 |
114095225 |
114095248 |
9 |
- |
26627737 |
HeLa |
viability after 8 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.6325666712715183 |
[361] |
[357,204,197] |
5 |
hSpCas9 |
negative selection |
1499446 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HeLa |
viability after 8 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.5084211152074252 |
[1214] |
[862,656,759] |
4 |
hSpCas9 |
negative selection |
1499447 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HeLa |
viability after 8 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.40713511276173214 |
[214] |
[124,13,225] |
4 |
hSpCas9 |
negative selection |
1499448 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HeLa |
viability after 8 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.13037673376287162 |
[1133] |
[683,664,318] |
1 |
hSpCas9 |
negative selection |
1499449 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HeLa |
viability after 8 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.4225709789260619 |
[647] |
[565,213,393] |
4 |
hSpCas9 |
negative selection |
1499450 |
114095049 |
114095072 |
9 |
- |
26627737 |
HeLa |
viability after 12 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.06087909796585378 |
[279] |
[82,157,85] |
0 |
hSpCas9 |
negative selection |
1581760 |
114095225 |
114095248 |
9 |
- |
26627737 |
HeLa |
viability after 12 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.09880382685306886 |
[361] |
[84,68,270] |
-1 |
hSpCas9 |
negative selection |
1581761 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HeLa |
viability after 12 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.0074002379229753945 |
[1214] |
[426,598,459] |
0 |
hSpCas9 |
negative selection |
1581762 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HeLa |
viability after 12 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.6575068724464419 |
[214] |
[92,206,111] |
5 |
hSpCas9 |
negative selection |
1581763 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HeLa |
viability after 12 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.23918337991945182 |
[1133] |
[482,641,522] |
2 |
hSpCas9 |
negative selection |
1581764 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HeLa |
viability after 12 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.18499094514138803 |
[647] |
[261,389,250] |
1 |
hSpCas9 |
negative selection |
1581765 |
114095049 |
114095072 |
9 |
- |
26627737 |
HeLa |
viability after 15 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.5411684825869943 |
[279] |
[119,77,32] |
-5 |
hSpCas9 |
negative selection |
1664075 |
114095225 |
114095248 |
9 |
- |
26627737 |
HeLa |
viability after 15 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.5113584188483435 |
[361] |
[188,248,190] |
4 |
hSpCas9 |
negative selection |
1664076 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HeLa |
viability after 15 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.011501380543282425 |
[1214] |
[504,426,543] |
0 |
hSpCas9 |
negative selection |
1664077 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HeLa |
viability after 15 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.8482545652161494 |
[214] |
[48,244,181] |
6 |
hSpCas9 |
negative selection |
1664078 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HeLa |
viability after 15 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.262021584010808 |
[1133] |
[517,797,327] |
2 |
hSpCas9 |
negative selection |
1664079 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HeLa |
viability after 15 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.8365877699510265 |
[647] |
[534,520,346] |
6 |
hSpCas9 |
negative selection |
1664080 |
114095049 |
114095072 |
9 |
- |
26627737 |
HeLa |
viability after 18 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.6088666943855382 |
[279] |
[81,53,32] |
-5 |
hSpCas9 |
negative selection |
1746390 |
114095225 |
114095248 |
9 |
- |
26627737 |
HeLa |
viability after 18 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.47069644133290506 |
[361] |
[117,202,190] |
4 |
hSpCas9 |
negative selection |
1746391 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HeLa |
viability after 18 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.00892240243868292 |
[1214] |
[336,357,543] |
0 |
hSpCas9 |
negative selection |
1746392 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HeLa |
viability after 18 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.8474522388207657 |
[214] |
[34,199,181] |
6 |
hSpCas9 |
negative selection |
1746393 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HeLa |
viability after 18 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2719381439902884 |
[1133] |
[353,661,327] |
2 |
hSpCas9 |
negative selection |
1746394 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HeLa |
viability after 18 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.7647892662032103 |
[647] |
[317,426,346] |
6 |
hSpCas9 |
negative selection |
1746395 |
114095049 |
114095072 |
9 |
- |
26627737 |
HCT116 |
viability after 6 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
1.3255356668170761 |
[237] |
[261,0] |
7 |
hSpCas9 |
negative selection |
1828705 |
114095225 |
114095248 |
9 |
- |
26627737 |
HCT116 |
viability after 6 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.11110497753420091 |
[655] |
[73,131] |
0 |
hSpCas9 |
negative selection |
1828706 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HCT116 |
viability after 6 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
1.6632559797776867 |
[1697] |
[528,1019] |
8 |
hSpCas9 |
negative selection |
1828707 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HCT116 |
viability after 6 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
-1.3571225789387493 |
[407] |
[64,2] |
-6 |
hSpCas9 |
negative selection |
1828708 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HCT116 |
viability after 6 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.2257286460558405 |
[1978] |
[1609,240] |
6 |
hSpCas9 |
negative selection |
1828709 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HCT116 |
viability after 6 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.1192133772283942 |
[1088] |
[165,152] |
0 |
hSpCas9 |
negative selection |
1828710 |
114095049 |
114095072 |
9 |
- |
26627737 |
HCT116 |
viability after 8 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
0.8096167506130987 |
[120] |
[72,175,100] |
7 |
hSpCas9 |
negative selection |
1911020 |
114095225 |
114095248 |
9 |
- |
26627737 |
HCT116 |
viability after 8 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.43051535071732455 |
[404] |
[120,211,162] |
-5 |
hSpCas9 |
negative selection |
1911021 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HCT116 |
viability after 8 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.06265531310560046 |
[1078] |
[500,582,621] |
0 |
hSpCas9 |
negative selection |
1911022 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HCT116 |
viability after 8 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
-0.12242636891957326 |
[106] |
[70,54,36] |
-1 |
hSpCas9 |
negative selection |
1911023 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HCT116 |
viability after 8 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.5861707364601522 |
[573] |
[637,445,344] |
6 |
hSpCas9 |
negative selection |
1911024 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HCT116 |
viability after 8 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.14470344066936003 |
[508] |
[245,262,251] |
-2 |
hSpCas9 |
negative selection |
1911025 |
114095049 |
114095072 |
9 |
- |
26627737 |
HCT116 |
viability after 9 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-1.2296549666269434 |
[237] |
[49,8] |
-7 |
hSpCas9 |
negative selection |
1993335 |
114095225 |
114095248 |
9 |
- |
26627737 |
HCT116 |
viability after 9 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.40821721807359607 |
[655] |
[313,167] |
3 |
hSpCas9 |
negative selection |
1993336 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HCT116 |
viability after 9 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.8512466532452627 |
[1697] |
[970,696] |
6 |
hSpCas9 |
negative selection |
1993337 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HCT116 |
viability after 9 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.4461394478146433 |
[407] |
[48,226] |
3 |
hSpCas9 |
negative selection |
1993338 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HCT116 |
viability after 9 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.11054708002840807 |
[1978] |
[322,620] |
0 |
hSpCas9 |
negative selection |
1993339 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HCT116 |
viability after 9 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.4657005177585497 |
[1088] |
[295,484] |
3 |
hSpCas9 |
negative selection |
1993340 |
114095049 |
114095072 |
9 |
- |
26627737 |
HCT116 |
viability after 12 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
0.44349317538656674 |
[120] |
[84,104,69] |
4 |
hSpCas9 |
negative selection |
2075650 |
114095225 |
114095248 |
9 |
- |
26627737 |
HCT116 |
viability after 12 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.015297508407301985 |
[404] |
[225,192,210] |
0 |
hSpCas9 |
negative selection |
2075651 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HCT116 |
viability after 12 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.0611925532410591 |
[1078] |
[712,501,546] |
0 |
hSpCas9 |
negative selection |
2075652 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HCT116 |
viability after 12 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.2800913409331178 |
[106] |
[54,67,82] |
3 |
hSpCas9 |
negative selection |
2075653 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HCT116 |
viability after 12 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.021657846776495 |
[573] |
[678,552,597] |
8 |
hSpCas9 |
negative selection |
2075654 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HCT116 |
viability after 12 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.27448614056342424 |
[508] |
[352,320,293] |
3 |
hSpCas9 |
negative selection |
2075655 |
114095049 |
114095072 |
9 |
- |
26627737 |
HCT116 |
viability after 15 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
0.18741276495915704 |
[120] |
[108,50,80] |
2 |
hSpCas9 |
negative selection |
2157965 |
114095225 |
114095248 |
9 |
- |
26627737 |
HCT116 |
viability after 15 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.28556046033621507 |
[404] |
[224,274,77] |
-3 |
hSpCas9 |
negative selection |
2157966 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HCT116 |
viability after 15 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.19505810544299274 |
[1078] |
[638,472,523] |
-2 |
hSpCas9 |
negative selection |
2157967 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HCT116 |
viability after 15 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.6281853921940355 |
[106] |
[174,51,67] |
6 |
hSpCas9 |
negative selection |
2157968 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HCT116 |
viability after 15 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.8966364210499315 |
[573] |
[546,671,613] |
7 |
hSpCas9 |
negative selection |
2157969 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HCT116 |
viability after 15 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.26341939395774583 |
[508] |
[485,309,273] |
2 |
hSpCas9 |
negative selection |
2157970 |
114095049 |
114095072 |
9 |
- |
26627737 |
HCT116 |
viability after 18 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
0.6697568537055629 |
[120] |
[98,74,106] |
5 |
hSpCas9 |
negative selection |
2240280 |
114095225 |
114095248 |
9 |
- |
26627737 |
HCT116 |
viability after 18 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.36790383575184843 |
[404] |
[123,78,261] |
-3 |
hSpCas9 |
negative selection |
2240281 |
114096151 |
114096174 |
9 |
+ |
26627737 |
HCT116 |
viability after 18 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.19926271046542388 |
[1078] |
[362,517,478] |
-2 |
hSpCas9 |
negative selection |
2240282 |
114096419 |
114096442 |
9 |
+ |
26627737 |
HCT116 |
viability after 18 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.24763575012337147 |
[106] |
[82,28,74] |
2 |
hSpCas9 |
negative selection |
2240283 |
114097375 |
114097398 |
9 |
+ |
26627737 |
HCT116 |
viability after 18 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.289096137799223 |
[573] |
[721,680,628] |
8 |
hSpCas9 |
negative selection |
2240284 |
114097622 |
114097645 |
9 |
+ |
26627737 |
HCT116 |
viability after 18 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.19620529590893965 |
[508] |
[202,320,320] |
1 |
hSpCas9 |
negative selection |
2240285 |
114099223 |
114099246 |
9 |
- |
25494202 |
A375 |
resistance to PLX-4720 (puromycin) |
CAGATCTTCAGACAGGTTCGAGG |
KIF12 |
ENSG00000136883 |
-1.3914763123349132 |
[289,700] |
[10,74] |
-7 |
dCas9-VP64 |
positive selection |
2463947 |
114099188 |
114099211 |
9 |
+ |
25494202 |
A375 |
resistance to PLX-4720 (puromycin) |
CTTATCATACCTGCACCTAGCGG |
KIF12 |
ENSG00000136883 |
0.876979629620545 |
[397,1955] |
[39,956] |
3 |
dCas9-VP64 |
positive selection |
2463948 |
114099129 |
114099152 |
9 |
- |
25494202 |
A375 |
resistance to PLX-4720 (puromycin) |
GGAGCAAGGGCCAGAGGGGCCGG |
KIF12 |
ENSG00000136883 |
-0.17768844463929723 |
[4,18] |
[0,2] |
0 |
dCas9-VP64 |
positive selection |
2463949 |
114099223 |
114099246 |
9 |
- |
25494202 |
A375 |
resistance to PLX-4720 (zeocin) |
CAGATCTTCAGACAGGTTCGAGG |
KIF12 |
ENSG00000136883 |
1.0081806804788176 |
[34,140] |
[20,90] |
6 |
dCas9-VP64 |
positive selection |
2559202 |
114099188 |
114099211 |
9 |
+ |
25494202 |
A375 |
resistance to PLX-4720 (zeocin) |
CTTATCATACCTGCACCTAGCGG |
KIF12 |
ENSG00000136883 |
-0.7441287611418039 |
[60,360] |
[37,41] |
-7 |
dCas9-VP64 |
positive selection |
2559203 |
114099129 |
114099152 |
9 |
- |
25494202 |
A375 |
resistance to PLX-4720 (zeocin) |
GGAGCAAGGGCCAGAGGGGCCGG |
KIF12 |
ENSG00000136883 |
0.17494490314220124 |
[57,40] |
[31,4] |
1 |
dCas9-VP64 |
positive selection |
2559204 |
114095057 |
114095080 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS1-dependent cytotoxicity |
AGCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
-0.28965997949126526 |
[4,4] |
[3,2] |
-4 |
hSpCas9 |
positive selection |
2997425 |
114094416 |
114094439 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS1-dependent cytotoxicity |
ATCTCTGTCTCCAAACGCTGGGG |
KIF12 |
ENSG00000136883 |
0.027059733022217425 |
[4,4] |
[4,3] |
0 |
hSpCas9 |
positive selection |
2997426 |
114096085 |
114096108 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS1-dependent cytotoxicity |
CCTCAAGCATCAGCTCCCCACGG |
KIF12 |
ENSG00000136883 |
0.06528896779414373 |
[3,3] |
[2,2] |
1 |
hSpCas9 |
positive selection |
2997427 |
114096397 |
114096420 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS1-dependent cytotoxicity |
GCTGATGTAAAGGGTGAGCAGGG |
KIF12 |
ENSG00000136883 |
0.5068254071276568 |
[3,3] |
[4,5] |
8 |
hSpCas9 |
positive selection |
2997428 |
114095057 |
114095080 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS2-dependent cytotoxicity |
AGCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
-0.19786331550095732 |
[4,4] |
[4,1] |
-3 |
hSpCas9 |
positive selection |
3065283 |
114094416 |
114094439 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS2-dependent cytotoxicity |
ATCTCTGTCTCCAAACGCTGGGG |
KIF12 |
ENSG00000136883 |
-0.2405456370354843 |
[4,4] |
[4,0] |
-4 |
hSpCas9 |
positive selection |
3065284 |
114096085 |
114096108 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS2-dependent cytotoxicity |
CCTCAAGCATCAGCTCCCCACGG |
KIF12 |
ENSG00000136883 |
0.615358690680558 |
[3,3] |
[2,3] |
8 |
hSpCas9 |
positive selection |
3065285 |
114096397 |
114096420 |
9 |
+ |
27453484 |
HT29 |
resistance to T3SS2-dependent cytotoxicity |
GCTGATGTAAAGGGTGAGCAGGG |
KIF12 |
ENSG00000136883 |
0.16267275299384698 |
[3,3] |
[3,2] |
3 |
hSpCas9 |
positive selection |
3065286 |
114095249 |
114095272 |
|
- |
24336571 |
A375 |
resistance to PLX after 7 days |
CAGCAAGCTCACCAAGTTGCTGG |
KIF12 |
ENSG00000136883 |
0.07471416976992501 |
[14,17] |
[18,15] |
2 |
hSpCas9 |
positive selection |
3123043 |
114094371 |
114094394 |
|
- |
24336571 |
A375 |
resistance to PLX after 7 days |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.11345293315519156 |
[8,10] |
[11,8] |
4 |
hSpCas9 |
positive selection |
3123044 |
114094413 |
114094436 |
|
+ |
24336571 |
A375 |
resistance to PLX after 7 days |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.03195347561775619 |
[4,4] |
[3,5] |
1 |
hSpCas9 |
positive selection |
3123045 |
114095261 |
114095284 |
|
+ |
24336571 |
A375 |
resistance to PLX after 7 days |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.01910632607081819 |
[5,4] |
[4,4] |
0 |
hSpCas9 |
positive selection |
3123046 |
114095249 |
114095272 |
|
- |
24336571 |
A375 |
resistance to PLX after 14 days |
CAGCAAGCTCACCAAGTTGCTGG |
KIF12 |
ENSG00000136883 |
-0.7213329810084195 |
[9,21] |
[4,3] |
-8 |
hSpCas9 |
positive selection |
3180836 |
114094371 |
114094394 |
|
- |
24336571 |
A375 |
resistance to PLX after 14 days |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.55775663501391 |
[9,12] |
[4,9] |
5 |
hSpCas9 |
positive selection |
3180837 |
114094413 |
114094436 |
|
+ |
24336571 |
A375 |
resistance to PLX after 14 days |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.08117982849789596 |
[3,4] |
[1,1] |
0 |
hSpCas9 |
positive selection |
3180838 |
114095261 |
114095284 |
|
+ |
24336571 |
A375 |
resistance to PLX after 14 days |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.5532449163416419 |
[4,5] |
[2,3] |
5 |
hSpCas9 |
positive selection |
3180839 |
114095249 |
114095272 |
|
- |
24336571 |
A375 |
viability after 7 days |
CAGCAAGCTCACCAAGTTGCTGG |
KIF12 |
ENSG00000136883 |
0.17644471233348952 |
[14] |
[14,17] |
2 |
hSpCas9 |
negative selection |
3238629 |
114094371 |
114094394 |
|
- |
24336571 |
A375 |
viability after 7 days |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.4881412052226894 |
[14] |
[8,10] |
-6 |
hSpCas9 |
negative selection |
3238630 |
114094413 |
114094436 |
|
+ |
24336571 |
A375 |
viability after 7 days |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
-1.313324611429809 |
[13] |
[4,4] |
-9 |
hSpCas9 |
negative selection |
3238631 |
114095261 |
114095284 |
|
+ |
24336571 |
A375 |
viability after 7 days |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.34673242586893405 |
[6] |
[5,4] |
-5 |
hSpCas9 |
negative selection |
3238632 |
114095249 |
114095272 |
|
- |
24336571 |
A375 |
viability after 14 days |
CAGCAAGCTCACCAAGTTGCTGG |
KIF12 |
ENSG00000136883 |
0.11402954584166136 |
[14] |
[9,21] |
1 |
hSpCas9 |
negative selection |
3296422 |
114094371 |
114094394 |
|
- |
24336571 |
A375 |
viability after 14 days |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.2735003580760116 |
[14] |
[9,12] |
-3 |
hSpCas9 |
negative selection |
3296423 |
114094413 |
114094436 |
|
+ |
24336571 |
A375 |
viability after 14 days |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
-1.414884546905313 |
[13] |
[3,4] |
-9 |
hSpCas9 |
negative selection |
3296424 |
114095261 |
114095284 |
|
+ |
24336571 |
A375 |
viability after 14 days |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.2783543831833101 |
[6] |
[4,5] |
-3 |
hSpCas9 |
negative selection |
3296425 |
114095261 |
114095284 |
9 |
+ |
27383988 |
293T |
resistance to West Nile virus (flavivirus) |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.5638392539465098 |
[206,206] |
[1,1] |
3 |
hSpCas9 |
positive selection |
3375725 |
114093427 |
114093450 |
9 |
- |
27383988 |
293T |
resistance to West Nile virus (flavivirus) |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
-0.9075807152298527 |
[286,286] |
[0,0] |
-6 |
hSpCas9 |
positive selection |
3375726 |
114094371 |
114094394 |
9 |
- |
27383988 |
293T |
resistance to West Nile virus (flavivirus) |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
1.9719239925835867 |
[38,38] |
[0,0] |
7 |
hSpCas9 |
positive selection |
3375727 |
114095056 |
114095079 |
9 |
+ |
26780180 |
HT29 |
viability (Avana library 4 designs) |
AGCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.668023212474685 |
[] |
[] |
2 |
hSpCas9 |
negative selection |
3434851 |
114094415 |
114094438 |
9 |
+ |
26780180 |
HT29 |
viability (Avana library 4 designs) |
ATCTCTGTCTCCAAACGCTGGGG |
KIF12 |
ENSG00000136883 |
0.57064033549603 |
[] |
[] |
2 |
hSpCas9 |
negative selection |
3434852 |
114096084 |
114096107 |
9 |
+ |
26780180 |
HT29 |
viability (Avana library 4 designs) |
CCTCAAGCATCAGCTCCCCACGG |
KIF12 |
ENSG00000136883 |
1.05129994195646 |
[] |
[] |
4 |
hSpCas9 |
negative selection |
3434853 |
114096396 |
114096419 |
9 |
+ |
26780180 |
HT29 |
viability (Avana library 4 designs) |
GCTGATGTAAAGGGTGAGCAGGG |
KIF12 |
ENSG00000136883 |
-0.266140346535273 |
[] |
[] |
-4 |
hSpCas9 |
negative selection |
3434854 |
114096396 |
114096419 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiCRISPRv2) |
GCTGATGTAAAGGGTGAGCAGGG |
KIF12 |
ENSG00000136883 |
2.06254087874819 |
[] |
[] |
3 |
hSpCas9 |
negative selection |
3522145 |
114095056 |
114095079 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiCRISPRv2) |
AGCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
3.44878299004089 |
[] |
[] |
5 |
hSpCas9 |
negative selection |
3522146 |
114094415 |
114094438 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiCRISPRv2) |
ATCTCTGTCTCCAAACGCTGGGG |
KIF12 |
ENSG00000136883 |
-5.56224808565759 |
[] |
[] |
-6 |
hSpCas9 |
negative selection |
3522147 |
114096084 |
114096107 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiCRISPRv2) |
CCTCAAGCATCAGCTCCCCACGG |
KIF12 |
ENSG00000136883 |
-7.15400626356114 |
[] |
[] |
-6 |
hSpCas9 |
negative selection |
3522148 |
114096177 |
114096200 |
9 |
- |
26780180 |
A375 |
viability (Avana lentiCRISPRv2) |
GATGCCTTCTGTGGACCCTGGGG |
KIF12 |
ENSG00000136883 |
-0.59249333903627 |
[] |
[] |
0 |
hSpCas9 |
negative selection |
3522149 |
114095298 |
114095321 |
9 |
- |
26780180 |
A375 |
viability (Avana lentiCRISPRv2) |
CCCTGCTGCTGGACCCACAGCGG |
KIF12 |
ENSG00000136883 |
4.18324181847772 |
[] |
[] |
7 |
hSpCas9 |
negative selection |
3522150 |
114096396 |
114096419 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiGuide) |
GCTGATGTAAAGGGTGAGCAGGG |
KIF12 |
ENSG00000136883 |
-2.8307377101805 |
[] |
[] |
-5 |
hSpCas9 |
negative selection |
3630804 |
114095056 |
114095079 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiGuide) |
AGCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
-0.671134631676295 |
[] |
[] |
-1 |
hSpCas9 |
negative selection |
3630805 |
114094415 |
114094438 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiGuide) |
ATCTCTGTCTCCAAACGCTGGGG |
KIF12 |
ENSG00000136883 |
7.59010656641824 |
[] |
[] |
6 |
hSpCas9 |
negative selection |
3630806 |
114096084 |
114096107 |
9 |
+ |
26780180 |
A375 |
viability (Avana lentiGuide) |
CCTCAAGCATCAGCTCCCCACGG |
KIF12 |
ENSG00000136883 |
5.35014812162625 |
[] |
[] |
5 |
hSpCas9 |
negative selection |
3630807 |
114096177 |
114096200 |
9 |
- |
26780180 |
A375 |
viability (Avana lentiGuide) |
GATGCCTTCTGTGGACCCTGGGG |
KIF12 |
ENSG00000136883 |
12.734353807815 |
[] |
[] |
7 |
hSpCas9 |
negative selection |
3630808 |
114095298 |
114095321 |
9 |
- |
26780180 |
A375 |
viability (Avana lentiGuide) |
CCCTGCTGCTGGACCCACAGCGG |
KIF12 |
ENSG00000136883 |
-2.80639521169186 |
[] |
[] |
-5 |
hSpCas9 |
negative selection |
3630809 |
114096396 |
114096419 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiCRISPRv2) |
GCTGATGTAAAGGGTGAGCAGGG |
KIF12 |
ENSG00000136883 |
0.18085933368521792 |
[4] |
[5,4] |
5 |
hSpCas9 |
positive selection |
3739463 |
114095056 |
114095079 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiCRISPRv2) |
AGCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.18161128818000996 |
[6] |
[6,6] |
5 |
hSpCas9 |
positive selection |
3739464 |
114094415 |
114094438 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiCRISPRv2) |
ATCTCTGTCTCCAAACGCTGGGG |
KIF12 |
ENSG00000136883 |
-0.38003206044749593 |
[6] |
[4,3] |
-5 |
hSpCas9 |
positive selection |
3739465 |
114096084 |
114096107 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiCRISPRv2) |
CCTCAAGCATCAGCTCCCCACGG |
KIF12 |
ENSG00000136883 |
-0.159309874073143 |
[4] |
[4,3] |
-3 |
hSpCas9 |
positive selection |
3739466 |
114096177 |
114096200 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiCRISPRv2) |
GATGCCTTCTGTGGACCCTGGGG |
KIF12 |
ENSG00000136883 |
0.187451459613378 |
[4] |
[5,5] |
5 |
hSpCas9 |
positive selection |
3739467 |
114095298 |
114095321 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiCRISPRv2) |
CCCTGCTGCTGGACCCACAGCGG |
KIF12 |
ENSG00000136883 |
0.29015550422841285 |
[4] |
[6,4] |
8 |
hSpCas9 |
positive selection |
3739468 |
114096396 |
114096419 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiGuide) |
GCTGATGTAAAGGGTGAGCAGGG |
KIF12 |
ENSG00000136883 |
0.3850504381804032 |
[5] |
[6,5] |
9 |
hSpCas9 |
positive selection |
3848070 |
114095056 |
114095079 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiGuide) |
AGCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
-0.12928405185238181 |
[6] |
[5,3] |
-2 |
hSpCas9 |
positive selection |
3848071 |
114094415 |
114094438 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiGuide) |
ATCTCTGTCTCCAAACGCTGGGG |
KIF12 |
ENSG00000136883 |
0.13158757779539898 |
[6] |
[6,5] |
3 |
hSpCas9 |
positive selection |
3848072 |
114096084 |
114096107 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiGuide) |
CCTCAAGCATCAGCTCCCCACGG |
KIF12 |
ENSG00000136883 |
0.15466608216718136 |
[5] |
[4,5] |
3 |
hSpCas9 |
positive selection |
3848073 |
114096177 |
114096200 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiGuide) |
GATGCCTTCTGTGGACCCTGGGG |
KIF12 |
ENSG00000136883 |
-0.3702616206800431 |
[6] |
[2,4] |
-5 |
hSpCas9 |
positive selection |
3848074 |
114095298 |
114095321 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (Avana lentiGuide) |
CCCTGCTGCTGGACCCACAGCGG |
KIF12 |
ENSG00000136883 |
0.26243568087509167 |
[5] |
[4,5] |
7 |
hSpCas9 |
positive selection |
3848075 |
114093427 |
114093450 |
9 |
- |
26780180 |
A375 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
-0.188639030813226 |
[] |
[] |
-5 |
hSpCas9 |
negative selection |
3954101 |
114094371 |
114094394 |
9 |
- |
26780180 |
A375 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.996488198857957 |
[] |
[] |
4 |
hSpCas9 |
negative selection |
3954102 |
114097301 |
114097324 |
9 |
+ |
26780180 |
A375 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.544866674145239 |
[] |
[] |
1 |
hSpCas9 |
negative selection |
3954103 |
114097375 |
114097398 |
9 |
+ |
26780180 |
A375 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.1678521792885 |
[] |
[] |
6 |
hSpCas9 |
negative selection |
3954104 |
114094413 |
114094436 |
9 |
+ |
26780180 |
A375 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
1.94285207217513 |
[] |
[] |
9 |
hSpCas9 |
negative selection |
3954105 |
114095261 |
114095284 |
9 |
+ |
26780180 |
A375 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
1.55769959888398 |
[] |
[] |
8 |
hSpCas9 |
negative selection |
3954106 |
114093427 |
114093450 |
9 |
- |
26780180 |
HT29 |
viability (GeCKOv2 library) |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.323588436790133 |
[] |
[] |
0 |
hSpCas9 |
negative selection |
4062067 |
114094371 |
114094394 |
9 |
- |
26780180 |
HT29 |
viability (GeCKOv2 library) |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.971265204801677 |
[] |
[] |
4 |
hSpCas9 |
negative selection |
4062068 |
114097301 |
114097324 |
9 |
+ |
26780180 |
HT29 |
viability (GeCKOv2 library) |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.671803584538382 |
[] |
[] |
2 |
hSpCas9 |
negative selection |
4062069 |
114097375 |
114097398 |
9 |
+ |
26780180 |
HT29 |
viability (GeCKOv2 library) |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.07997976343934 |
[] |
[] |
5 |
hSpCas9 |
negative selection |
4062070 |
114094413 |
114094436 |
9 |
+ |
26780180 |
HT29 |
viability (GeCKOv2 library) |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
1.0180093497059 |
[] |
[] |
4 |
hSpCas9 |
negative selection |
4062071 |
114095261 |
114095284 |
9 |
+ |
26780180 |
HT29 |
viability (GeCKOv2 library) |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.950423519835029 |
[] |
[] |
4 |
hSpCas9 |
negative selection |
4062072 |
114095249 |
114095272 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) |
CAGCAAGCTCACCAAGTTGCTGG |
KIF12 |
ENSG00000136883 |
-0.09075626396981527 |
[3] |
[2,1] |
-2 |
hSpCas9 |
positive selection |
4146956 |
114094371 |
114094394 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.0028619580621646323 |
[3] |
[1,2] |
0 |
hSpCas9 |
positive selection |
4146957 |
114094413 |
114094436 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
-0.19839825619890356 |
[2] |
[1,0] |
-5 |
hSpCas9 |
positive selection |
4146958 |
114095261 |
114095284 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.24088565769932468 |
[3] |
[1,1] |
-5 |
hSpCas9 |
positive selection |
4146959 |
114095249 |
114095272 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiGuide) |
CAGCAAGCTCACCAAGTTGCTGG |
KIF12 |
ENSG00000136883 |
-0.3102366501710774 |
[4] |
[0,0,4,0] |
-4 |
hSpCas9 |
positive selection |
4210978 |
114094371 |
114094394 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiGuide) |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.6551862756403913 |
[2] |
[5,0,4,0] |
4 |
hSpCas9 |
positive selection |
4210979 |
114094413 |
114094436 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiGuide) |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.11012236812168005 |
[3] |
[2,4,1,0] |
0 |
hSpCas9 |
positive selection |
4210980 |
114095261 |
114095284 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv1 lentiGuide) |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.3761060397775715 |
[2] |
[1,0,0,0] |
-5 |
hSpCas9 |
positive selection |
4210981 |
114097375 |
114097398 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv2 lentiGuide) |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.24650711627399377 |
[2] |
[3,2] |
5 |
hSpCas9 |
positive selection |
4278530 |
114097301 |
114097324 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv2 lentiGuide) |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.12596402287927144 |
[1] |
[1,0] |
2 |
hSpCas9 |
positive selection |
4278531 |
114094413 |
114094436 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv2 lentiGuide) |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.25283182648764163 |
[3] |
[1,3] |
5 |
hSpCas9 |
positive selection |
4278532 |
114095261 |
114095284 |
9 |
+ |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv2 lentiGuide) |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.03167700332776566 |
[2] |
[2,1] |
0 |
hSpCas9 |
positive selection |
4342786 |
114093427 |
114093450 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv2 lentiGuide) |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.31763613953672054 |
[3] |
[4,2] |
6 |
hSpCas9 |
positive selection |
4342787 |
114094371 |
114094394 |
9 |
- |
26780180 |
A375 |
resistance to vemurafenib (GeCKOv2 lentiGuide) |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.1344131595840411 |
[1] |
[1,0] |
-3 |
hSpCas9 |
positive selection |
4342788 |
114096462 |
114096484 |
9 |
- |
27760321 |
OCIAML3 |
viability |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.4057738523188987 |
[667,514] |
[590,630] |
5 |
hSpCas9 |
negative selection |
4412162 |
114097376 |
114097398 |
9 |
+ |
27760321 |
OCIAML3 |
viability |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2745907003695723 |
[461,378] |
[358,443] |
3 |
hSpCas9 |
negative selection |
4412163 |
114095031 |
114095053 |
9 |
- |
27760321 |
OCIAML3 |
viability |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.39084853116064344 |
[805,627] |
[559,951] |
5 |
hSpCas9 |
negative selection |
4412164 |
114095057 |
114095079 |
9 |
+ |
27760321 |
OCIAML3 |
viability |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.7322868947181327 |
[791,693] |
[872,1080] |
8 |
hSpCas9 |
negative selection |
4412165 |
114095200 |
114095222 |
9 |
+ |
27760321 |
OCIAML3 |
viability |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.8783095366497957 |
[435,386] |
[584,597] |
8 |
hSpCas9 |
negative selection |
4412166 |
114096462 |
114096484 |
9 |
- |
27760321 |
OCIAML2 |
viability |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.3340901893148433 |
[667,514] |
[486,745] |
4 |
hSpCas9 |
negative selection |
4495625 |
114097376 |
114097398 |
9 |
+ |
27760321 |
OCIAML2 |
viability |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2260647861944674 |
[461,378] |
[297,524] |
3 |
hSpCas9 |
negative selection |
4495626 |
114095031 |
114095053 |
9 |
- |
27760321 |
OCIAML2 |
viability |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.495099975386171 |
[805,627] |
[728,920] |
6 |
hSpCas9 |
negative selection |
4495627 |
114095057 |
114095079 |
9 |
+ |
27760321 |
OCIAML2 |
viability |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.12447409426609635 |
[791,693] |
[491,866] |
1 |
hSpCas9 |
negative selection |
4495628 |
114095200 |
114095222 |
9 |
+ |
27760321 |
OCIAML2 |
viability |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.19326079418057568 |
[435,386] |
[338,433] |
2 |
hSpCas9 |
negative selection |
4495629 |
114096462 |
114096484 |
9 |
- |
27760321 |
MV411 |
viability |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
1.1945174790810118 |
[667,514] |
[1120,534] |
8 |
hSpCas9 |
negative selection |
4579088 |
114097376 |
114097398 |
9 |
+ |
27760321 |
MV411 |
viability |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.1197374700076806 |
[461,378] |
[202,330] |
-1 |
hSpCas9 |
negative selection |
4579089 |
114095031 |
114095053 |
9 |
- |
27760321 |
MV411 |
viability |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.8861716095999058 |
[805,627] |
[706,1110] |
6 |
hSpCas9 |
negative selection |
4579090 |
114095057 |
114095079 |
9 |
+ |
27760321 |
MV411 |
viability |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
-0.4915070594551869 |
[791,693] |
[351,341] |
-3 |
hSpCas9 |
negative selection |
4579091 |
114095200 |
114095222 |
9 |
+ |
27760321 |
MV411 |
viability |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
-0.04430926235458807 |
[435,386] |
[158,418] |
0 |
hSpCas9 |
negative selection |
4579092 |
114096462 |
114096484 |
9 |
- |
27760321 |
HL60 |
viability |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.1496554996868517 |
[667,514] |
[467,599] |
1 |
hSpCas9 |
negative selection |
4662551 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HL60 |
viability |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.12786643446577112 |
[461,378] |
[307,442] |
1 |
hSpCas9 |
negative selection |
4662552 |
114095031 |
114095053 |
9 |
- |
27760321 |
HL60 |
viability |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.4419521361315256 |
[805,627] |
[794,784] |
5 |
hSpCas9 |
negative selection |
4662553 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HL60 |
viability |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.29541191849004544 |
[791,693] |
[685,803] |
3 |
hSpCas9 |
negative selection |
4662554 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HL60 |
viability |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
-0.3684896624450218 |
[435,386] |
[241,278] |
-4 |
hSpCas9 |
negative selection |
4662555 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT1080 |
viability |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
-0.2590734775452076 |
[514,401] |
[186,114] |
-1 |
hSpCas9 |
negative selection |
4746014 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT1080 |
viability |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.9891427124232621 |
[378,295] |
[560,503] |
9 |
hSpCas9 |
negative selection |
4746015 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT1080 |
viability |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.9909484083734111 |
[627,489] |
[475,405] |
5 |
hSpCas9 |
negative selection |
4746016 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT1080 |
viability |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
-0.08051164067129069 |
[693,541] |
[376,74] |
0 |
hSpCas9 |
negative selection |
4746017 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT1080 |
viability |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
1.4742367465010777 |
[386,301] |
[513,235] |
7 |
hSpCas9 |
negative selection |
4746018 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT29 |
viability after 7 days |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.01932057490577216 |
[514,401] |
[687,537,578] |
0 |
hSpCas9 |
negative selection |
4829477 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT29 |
viability after 7 days |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.011768723344510998 |
[378,295] |
[431,400,456] |
0 |
hSpCas9 |
negative selection |
4829478 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT29 |
viability after 7 days |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.34392577017608794 |
[627,489] |
[948,1086,710] |
5 |
hSpCas9 |
negative selection |
4829479 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT29 |
viability after 7 days |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.7059019636881756 |
[693,541] |
[1498,1360,1062] |
9 |
hSpCas9 |
negative selection |
4829480 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT29 |
viability after 7 days |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.5747441206429967 |
[386,301] |
[636,744,594] |
8 |
hSpCas9 |
negative selection |
4829481 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT29 |
viability after 25 days |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.9264732308085594 |
[514,401] |
[900,915,1195] |
9 |
hSpCas9 |
negative selection |
4912940 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT29 |
viability after 25 days |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.10195488945333839 |
[378,295] |
[560,213,461] |
1 |
hSpCas9 |
negative selection |
4912941 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT29 |
viability after 25 days |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.6300188189972883 |
[627,489] |
[722,1020,1265] |
7 |
hSpCas9 |
negative selection |
4912942 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT29 |
viability after 25 days |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.9645229096293626 |
[693,541] |
[1386,1290,1462] |
9 |
hSpCas9 |
negative selection |
4912943 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT29 |
viability after 25 days |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.826735095620928 |
[386,301] |
[623,926,529] |
8 |
hSpCas9 |
negative selection |
4912944 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT29 |
viability after 22 days |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.829361328993733 |
[514,401] |
[983,937,901] |
8 |
hSpCas9 |
negative selection |
4996403 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT29 |
viability after 22 days |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2373410901863891 |
[378,295] |
[521,413,441] |
2 |
hSpCas9 |
negative selection |
4996404 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT29 |
viability after 22 days |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.5958505388627374 |
[627,489] |
[880,1029,1021] |
6 |
hSpCas9 |
negative selection |
4996405 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT29 |
viability after 22 days |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.5912920208268457 |
[693,541] |
[993,891,1347] |
6 |
hSpCas9 |
negative selection |
4996406 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT29 |
viability after 22 days |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.8396573599094209 |
[386,301] |
[762,848,522] |
8 |
hSpCas9 |
negative selection |
4996407 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT29 |
viability after 19 days |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
1.013210723815499 |
[514,401] |
[1008,824,1324] |
9 |
hSpCas9 |
negative selection |
5079866 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT29 |
viability after 19 days |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.06626344001873896 |
[378,295] |
[458,624,143] |
0 |
hSpCas9 |
negative selection |
5079867 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT29 |
viability after 19 days |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.6683883149106501 |
[627,489] |
[714,991,1297] |
6 |
hSpCas9 |
negative selection |
5079868 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT29 |
viability after 19 days |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.6666129162816312 |
[693,541] |
[1362,841,1182] |
6 |
hSpCas9 |
negative selection |
5079869 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT29 |
viability after 19 days |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
1.0044530408262033 |
[386,301] |
[494,1005,836] |
9 |
hSpCas9 |
negative selection |
5079870 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT29 |
viability after 16 days |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.6027907019805135 |
[514,401] |
[629,774,917] |
7 |
hSpCas9 |
negative selection |
5163329 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT29 |
viability after 16 days |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.01573152308239817 |
[378,295] |
[562,393,204] |
0 |
hSpCas9 |
negative selection |
5163330 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT29 |
viability after 16 days |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.2317411723769527 |
[627,489] |
[860,656,698] |
2 |
hSpCas9 |
negative selection |
5163331 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT29 |
viability after 16 days |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.2820706009639733 |
[693,541] |
[1327,655,588] |
3 |
hSpCas9 |
negative selection |
5163332 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT29 |
viability after 16 days |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.6456089032401042 |
[386,301] |
[543,610,647] |
7 |
hSpCas9 |
negative selection |
5163333 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT29 |
viability after 13 days |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.491895292223119 |
[514,401] |
[748,713,778] |
6 |
hSpCas9 |
negative selection |
5246792 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT29 |
viability after 13 days |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.20017928864630724 |
[378,295] |
[296,375,348] |
-2 |
hSpCas9 |
negative selection |
5246793 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT29 |
viability after 13 days |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.5359044477830911 |
[627,489] |
[1133,830,859] |
7 |
hSpCas9 |
negative selection |
5246794 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT29 |
viability after 13 days |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.5591444941506576 |
[693,541] |
[1336,854,980] |
7 |
hSpCas9 |
negative selection |
5246795 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT29 |
viability after 13 days |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.36873342512475876 |
[386,301] |
[419,607,519] |
4 |
hSpCas9 |
negative selection |
5246796 |
114096462 |
114096484 |
9 |
- |
27760321 |
HT29 |
viability after 10 days |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
0.6052768686996118 |
[514,401] |
[774,943,894] |
8 |
hSpCas9 |
negative selection |
5330255 |
114097376 |
114097398 |
9 |
+ |
27760321 |
HT29 |
viability after 10 days |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.16419429303940963 |
[378,295] |
[698,279,432] |
2 |
hSpCas9 |
negative selection |
5330256 |
114095031 |
114095053 |
9 |
- |
27760321 |
HT29 |
viability after 10 days |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.3058167989043349 |
[627,489] |
[631,1285,685] |
4 |
hSpCas9 |
negative selection |
5330257 |
114095057 |
114095079 |
9 |
+ |
27760321 |
HT29 |
viability after 10 days |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.6435579002096516 |
[693,541] |
[1415,1088,1109] |
8 |
hSpCas9 |
negative selection |
5330258 |
114095200 |
114095222 |
9 |
+ |
27760321 |
HT29 |
viability after 10 days |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.7392108911003455 |
[386,301] |
[534,862,758] |
8 |
hSpCas9 |
negative selection |
5330259 |
114096462 |
114096484 |
9 |
- |
27760321 |
MOLM13 |
viability |
TCCAGGTCTCAGCCGTCGAAGG |
KIF12 |
ENSG00000136883 |
-0.2181921241389743 |
[667,514] |
[159,390] |
-1 |
hSpCas9 |
negative selection |
5413718 |
114097376 |
114097398 |
9 |
+ |
27760321 |
MOLM13 |
viability |
GAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.21116122518164476 |
[461,378] |
[291,128] |
-1 |
hSpCas9 |
negative selection |
5413719 |
114095031 |
114095053 |
9 |
- |
27760321 |
MOLM13 |
viability |
CGGGTCACCACCCGACCACAGG |
KIF12 |
ENSG00000136883 |
0.9230557256014372 |
[805,627] |
[966,586] |
6 |
hSpCas9 |
negative selection |
5413720 |
114095057 |
114095079 |
9 |
+ |
27760321 |
MOLM13 |
viability |
GCTCGGCTTGCATATCGCAGGG |
KIF12 |
ENSG00000136883 |
0.6404184091328662 |
[791,693] |
[637,663] |
4 |
hSpCas9 |
negative selection |
5413721 |
114095200 |
114095222 |
9 |
+ |
27760321 |
MOLM13 |
viability |
CCCCGCTTAAGTACCATGAGGG |
KIF12 |
ENSG00000136883 |
0.47048004190299364 |
[435,386] |
[365,282] |
3 |
hSpCas9 |
negative selection |
5413722 |
114099154 |
114099177 |
9 |
+ |
27661255 |
K562 |
viability |
GCTCCGCGCGAGATCCCTGTGGG |
KIF12 |
ENSG00000136883 |
-0.0909584256824135 |
[654,687] |
[608,412] |
-3 |
dCas9-KRAB |
negative selection |
5488589 |
114099063 |
114099086 |
9 |
- |
27661255 |
K562 |
viability |
GGAGGCACCTGGGCGAGACAAGG |
KIF12 |
ENSG00000136883 |
0.04249387002873689 |
[909,932] |
[848,679] |
1 |
dCas9-KRAB |
negative selection |
5488590 |
114097375 |
114097398 |
9 |
+ |
27260156 |
BXPC3 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.23670949737051475 |
[412] |
[509,449,509,572] |
5 |
hSpCas9 |
negative selection |
5550990 |
114097301 |
114097324 |
9 |
+ |
27260156 |
BXPC3 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.5415416088603595 |
[66] |
[81,94,149,80] |
9 |
hSpCas9 |
negative selection |
5550991 |
114094413 |
114094436 |
9 |
+ |
27260156 |
BXPC3 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
-0.14908888173072868 |
[557] |
[530,458,493,632] |
-3 |
hSpCas9 |
negative selection |
5550992 |
114095261 |
114095284 |
9 |
+ |
27260156 |
BXPC3 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.12972874055717262 |
[424] |
[448,369,318,489] |
-3 |
hSpCas9 |
negative selection |
5615246 |
114093427 |
114093450 |
9 |
- |
27260156 |
BXPC3 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.45955087421280605 |
[745] |
[920,978,1251,1167] |
8 |
hSpCas9 |
negative selection |
5615247 |
114094371 |
114094394 |
9 |
- |
27260156 |
BXPC3 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.1528114261867919 |
[127] |
[92,92,174,125] |
-4 |
hSpCas9 |
negative selection |
5615248 |
114097375 |
114097398 |
9 |
+ |
27260156 |
A673 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2822936786807162 |
[412] |
[684,615,516,602] |
6 |
hSpCas9 |
negative selection |
5672241 |
114097301 |
114097324 |
9 |
+ |
27260156 |
A673 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.8530512058631077 |
[66] |
[176,103,196,104] |
9 |
hSpCas9 |
negative selection |
5672242 |
114094413 |
114094436 |
9 |
+ |
27260156 |
A673 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.2308397697678463 |
[557] |
[718,595,911,919] |
5 |
hSpCas9 |
negative selection |
5672243 |
114095261 |
114095284 |
9 |
+ |
27260156 |
A673 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.03506618069307217 |
[424] |
[619,464,471,547] |
0 |
hSpCas9 |
negative selection |
5736497 |
114093427 |
114093450 |
9 |
- |
27260156 |
A673 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.3061198630932518 |
[745] |
[1160,1118,1062,1089] |
7 |
hSpCas9 |
negative selection |
5736498 |
114094371 |
114094394 |
9 |
- |
27260156 |
A673 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.15848206722936764 |
[127] |
[100,107,148,191] |
-4 |
hSpCas9 |
negative selection |
5736499 |
114097375 |
114097398 |
9 |
+ |
27260156 |
A375 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.12653114693585563 |
[412] |
[611,721,408,403] |
1 |
hSpCas9 |
negative selection |
5793492 |
114097301 |
114097324 |
9 |
+ |
27260156 |
A375 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.072467619454879 |
[66] |
[164,183,161,150] |
9 |
hSpCas9 |
negative selection |
5793493 |
114094413 |
114094436 |
9 |
+ |
27260156 |
A375 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.2748942996233221 |
[557] |
[835,879,685,764] |
4 |
hSpCas9 |
negative selection |
5793494 |
114095261 |
114095284 |
9 |
+ |
27260156 |
A375 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.09831095785822304 |
[424] |
[437,666,581,462] |
1 |
hSpCas9 |
negative selection |
5857748 |
114093427 |
114093450 |
9 |
- |
27260156 |
A375 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.5764709829057262 |
[745] |
[1325,1763,1098,1092] |
8 |
hSpCas9 |
negative selection |
5857749 |
114094371 |
114094394 |
9 |
- |
27260156 |
A375 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.49419399329192526 |
[127] |
[234,275,195,150] |
7 |
hSpCas9 |
negative selection |
5857750 |
114097375 |
114097398 |
9 |
+ |
27260156 |
COLO741 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.3539331103351265 |
[412] |
[743,685,602] |
7 |
hSpCas9 |
negative selection |
5914743 |
114097301 |
114097324 |
9 |
+ |
27260156 |
COLO741 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.27659308740994204 |
[66] |
[102,78,126] |
6 |
hSpCas9 |
negative selection |
5914744 |
114094413 |
114094436 |
9 |
+ |
27260156 |
COLO741 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.21167518752269596 |
[557] |
[918,838,731] |
4 |
hSpCas9 |
negative selection |
5914745 |
114095261 |
114095284 |
9 |
+ |
27260156 |
COLO741 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.027974551330613412 |
[424] |
[440,642,506] |
0 |
hSpCas9 |
negative selection |
5978999 |
114093427 |
114093450 |
9 |
- |
27260156 |
COLO741 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.5569996267334536 |
[745] |
[1581,1322,1319] |
9 |
hSpCas9 |
negative selection |
5979000 |
114094371 |
114094394 |
9 |
- |
27260156 |
COLO741 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.28909326600389074 |
[127] |
[294,154,159] |
6 |
hSpCas9 |
negative selection |
5979001 |
114097375 |
114097398 |
9 |
+ |
27260156 |
CAL120 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.24359374623925928 |
[412] |
[632,540,653] |
3 |
hSpCas9 |
negative selection |
6035994 |
114097301 |
114097324 |
9 |
+ |
27260156 |
CAL120 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.5160811136062295 |
[66] |
[156,68,136] |
7 |
hSpCas9 |
negative selection |
6035995 |
114094413 |
114094436 |
9 |
+ |
27260156 |
CAL120 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.2260581190949054 |
[557] |
[788,906,737] |
3 |
hSpCas9 |
negative selection |
6035996 |
114095261 |
114095284 |
9 |
+ |
27260156 |
CAL120 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.09280788660044731 |
[424] |
[503,460,714] |
1 |
hSpCas9 |
negative selection |
6100250 |
114093427 |
114093450 |
9 |
- |
27260156 |
CAL120 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.673268551629369 |
[745] |
[2013,1374,1137] |
8 |
hSpCas9 |
negative selection |
6100251 |
114094371 |
114094394 |
9 |
- |
27260156 |
CAL120 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.3900425894414359 |
[127] |
[247,174,208] |
6 |
hSpCas9 |
negative selection |
6100252 |
114097375 |
114097398 |
9 |
+ |
27260156 |
CADOES1 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.05105728493842318 |
[412] |
[367,389,279,447] |
-1 |
hSpCas9 |
negative selection |
6157245 |
114097301 |
114097324 |
9 |
+ |
27260156 |
CADOES1 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.9284441343862821 |
[66] |
[109,114,140,107] |
9 |
hSpCas9 |
negative selection |
6157246 |
114094413 |
114094436 |
9 |
+ |
27260156 |
CADOES1 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.04537821306024012 |
[557] |
[524,459,495,665] |
0 |
hSpCas9 |
negative selection |
6157247 |
114095261 |
114095284 |
9 |
+ |
27260156 |
CADOES1 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.21977321100680833 |
[424] |
[488,499,373,478] |
4 |
hSpCas9 |
negative selection |
6221501 |
114093427 |
114093450 |
9 |
- |
27260156 |
CADOES1 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.46215571369807407 |
[745] |
[780,1237,856,947] |
7 |
hSpCas9 |
negative selection |
6221502 |
114094371 |
114094394 |
9 |
- |
27260156 |
CADOES1 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.3292269064004796 |
[127] |
[104,107,165,221] |
5 |
hSpCas9 |
negative selection |
6221503 |
114097375 |
114097398 |
9 |
+ |
27260156 |
EWS502 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.19893813539746258 |
[412] |
[351,525,448,710] |
3 |
hSpCas9 |
negative selection |
6278496 |
114097301 |
114097324 |
9 |
+ |
27260156 |
EWS502 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.7534612408225883 |
[66] |
[55,133,79,221] |
9 |
hSpCas9 |
negative selection |
6278497 |
114094413 |
114094436 |
9 |
+ |
27260156 |
EWS502 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.3945383616901731 |
[557] |
[466,883,838,961] |
7 |
hSpCas9 |
negative selection |
6278498 |
114095261 |
114095284 |
9 |
+ |
27260156 |
EWS502 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.43338067834888694 |
[424] |
[572,747,611,485] |
7 |
hSpCas9 |
negative selection |
6342752 |
114093427 |
114093450 |
9 |
- |
27260156 |
EWS502 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.6025644275013178 |
[745] |
[893,1289,1162,1501] |
9 |
hSpCas9 |
negative selection |
6342753 |
114094371 |
114094394 |
9 |
- |
27260156 |
EWS502 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.03466158861131374 |
[127] |
[163,111,185,87] |
0 |
hSpCas9 |
negative selection |
6342754 |
114097375 |
114097398 |
9 |
+ |
27260156 |
EW8 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.19454048452810394 |
[412] |
[415,380,218,545] |
3 |
hSpCas9 |
negative selection |
6399747 |
114097301 |
114097324 |
9 |
+ |
27260156 |
EW8 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.7966679835841743 |
[66] |
[125,76,36,149] |
9 |
hSpCas9 |
negative selection |
6399748 |
114094413 |
114094436 |
9 |
+ |
27260156 |
EW8 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.228431883387857 |
[557] |
[545,496,500,579] |
4 |
hSpCas9 |
negative selection |
6399749 |
114095261 |
114095284 |
9 |
+ |
27260156 |
EW8 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.1285433705281421 |
[424] |
[434,352,396,322] |
2 |
hSpCas9 |
negative selection |
6464003 |
114093427 |
114093450 |
9 |
- |
27260156 |
EW8 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.45086383745205416 |
[745] |
[785,735,680,1118] |
7 |
hSpCas9 |
negative selection |
6464004 |
114094371 |
114094394 |
9 |
- |
27260156 |
EW8 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.35414524275884696 |
[127] |
[95,137,197,82] |
6 |
hSpCas9 |
negative selection |
6464005 |
114097375 |
114097398 |
9 |
+ |
27260156 |
CORL105 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.1465569214701135 |
[412] |
[432,405,440,467] |
-3 |
hSpCas9 |
negative selection |
6520998 |
114097301 |
114097324 |
9 |
+ |
27260156 |
CORL105 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.1262049642552099 |
[66] |
[100,184,271,139] |
9 |
hSpCas9 |
negative selection |
6520999 |
114094413 |
114094436 |
9 |
+ |
27260156 |
CORL105 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.24408140926598051 |
[557] |
[787,527,1012,807] |
4 |
hSpCas9 |
negative selection |
6521000 |
114095261 |
114095284 |
9 |
+ |
27260156 |
CORL105 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.28392746883789266 |
[424] |
[661,422,781,588] |
5 |
hSpCas9 |
negative selection |
6585254 |
114093427 |
114093450 |
9 |
- |
27260156 |
CORL105 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.4002074546329313 |
[745] |
[1204,1141,1196,1074] |
7 |
hSpCas9 |
negative selection |
6585255 |
114094371 |
114094394 |
9 |
- |
27260156 |
CORL105 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.3589962848986503 |
[127] |
[94,83,116,170] |
-6 |
hSpCas9 |
negative selection |
6585256 |
114097375 |
114097398 |
9 |
+ |
27260156 |
HS294T |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.26130007399909294 |
[412] |
[119,168,117,123] |
-4 |
hSpCas9 |
negative selection |
6642249 |
114097301 |
114097324 |
9 |
+ |
27260156 |
HS294T |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.6207033598403067 |
[66] |
[59,27,27,41] |
7 |
hSpCas9 |
negative selection |
6642250 |
114094413 |
114094436 |
9 |
+ |
27260156 |
HS294T |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.5636298808745308 |
[557] |
[314,400,221,336] |
7 |
hSpCas9 |
negative selection |
6642251 |
114095261 |
114095284 |
9 |
+ |
27260156 |
HS294T |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.3878427015549024 |
[424] |
[153,275,183,255] |
5 |
hSpCas9 |
negative selection |
6706505 |
114093427 |
114093450 |
9 |
- |
27260156 |
HS294T |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.9549533433045982 |
[745] |
[510,521,321,950] |
9 |
hSpCas9 |
negative selection |
6706506 |
114094371 |
114094394 |
9 |
- |
27260156 |
HS294T |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.5567428006530557 |
[127] |
[33,18,42,39] |
-7 |
hSpCas9 |
negative selection |
6706507 |
114097375 |
114097398 |
9 |
+ |
27260156 |
HCC44 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2975337249531594 |
[412] |
[625,425,660,617] |
5 |
hSpCas9 |
negative selection |
6763500 |
114097301 |
114097324 |
9 |
+ |
27260156 |
HCC44 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.8565196408274127 |
[66] |
[243,28,181,125] |
9 |
hSpCas9 |
negative selection |
6763501 |
114094413 |
114094436 |
9 |
+ |
27260156 |
HCC44 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.12112190150403915 |
[557] |
[905,360,1047,557] |
2 |
hSpCas9 |
negative selection |
6763502 |
114095261 |
114095284 |
9 |
+ |
27260156 |
HCC44 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.03205947735740522 |
[424] |
[727,375,405,394] |
0 |
hSpCas9 |
negative selection |
6827756 |
114093427 |
114093450 |
9 |
- |
27260156 |
HCC44 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.48880606297621143 |
[745] |
[1170,1073,1331,1188] |
7 |
hSpCas9 |
negative selection |
6827757 |
114094371 |
114094394 |
9 |
- |
27260156 |
HCC44 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.25819702143963985 |
[127] |
[131,68,160,135] |
-4 |
hSpCas9 |
negative selection |
6827758 |
114097375 |
114097398 |
9 |
+ |
27260156 |
G402 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.5338906724601156 |
[412] |
[599,1489,584,287] |
6 |
hSpCas9 |
negative selection |
6884751 |
114097301 |
114097324 |
9 |
+ |
27260156 |
G402 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.5442677193873762 |
[66] |
[160,245,421,118] |
9 |
hSpCas9 |
negative selection |
6884752 |
114094413 |
114094436 |
9 |
+ |
27260156 |
G402 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.24612939359238736 |
[557] |
[583,936,974,710] |
3 |
hSpCas9 |
negative selection |
6884753 |
114095261 |
114095284 |
9 |
+ |
27260156 |
G402 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.16770328460701409 |
[424] |
[576,546,396,350] |
-2 |
hSpCas9 |
negative selection |
6949007 |
114093427 |
114093450 |
9 |
- |
27260156 |
G402 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.731857986399197 |
[745] |
[1649,1461,1217,1717] |
8 |
hSpCas9 |
negative selection |
6949008 |
114094371 |
114094394 |
9 |
- |
27260156 |
G402 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.9297931586797943 |
[127] |
[132,63,55,80] |
-8 |
hSpCas9 |
negative selection |
6949009 |
114097375 |
114097398 |
9 |
+ |
27260156 |
L33 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.13976042344924672 |
[412] |
[287,155,324,316] |
-3 |
hSpCas9 |
negative selection |
7006002 |
114097301 |
114097324 |
9 |
+ |
27260156 |
L33 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.9219049738072211 |
[66] |
[93,40,52,228] |
9 |
hSpCas9 |
negative selection |
7006003 |
114094413 |
114094436 |
9 |
+ |
27260156 |
L33 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.27391842570458114 |
[557] |
[541,256,399,893] |
6 |
hSpCas9 |
negative selection |
7006004 |
114095261 |
114095284 |
9 |
+ |
27260156 |
L33 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.22152261977065124 |
[424] |
[421,190,375,497] |
5 |
hSpCas9 |
negative selection |
7070258 |
114093427 |
114093450 |
9 |
- |
27260156 |
L33 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.2558505986319677 |
[745] |
[874,359,544,941] |
5 |
hSpCas9 |
negative selection |
7070259 |
114094371 |
114094394 |
9 |
- |
27260156 |
L33 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.0784643107769396 |
[127] |
[112,63,87,131] |
1 |
hSpCas9 |
negative selection |
7070260 |
114097375 |
114097398 |
9 |
+ |
27260156 |
K562 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.32740836555254826 |
[412] |
[389,402,369,643] |
4 |
hSpCas9 |
negative selection |
7127253 |
114097301 |
114097324 |
9 |
+ |
27260156 |
K562 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.3724410149214608 |
[66] |
[117,187,12,279] |
9 |
hSpCas9 |
negative selection |
7127254 |
114094413 |
114094436 |
9 |
+ |
27260156 |
K562 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.18568395419462183 |
[557] |
[485,499,259,948] |
2 |
hSpCas9 |
negative selection |
7127255 |
114095261 |
114095284 |
9 |
+ |
27260156 |
K562 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.34154440119478036 |
[424] |
[340,798,549,251] |
4 |
hSpCas9 |
negative selection |
7191509 |
114093427 |
114093450 |
9 |
- |
27260156 |
K562 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.6758284564121921 |
[745] |
[1284,649,899,1352] |
8 |
hSpCas9 |
negative selection |
7191510 |
114094371 |
114094394 |
9 |
- |
27260156 |
K562 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.08114343836035776 |
[127] |
[118,77,81,144] |
-1 |
hSpCas9 |
negative selection |
7191511 |
114097375 |
114097398 |
9 |
+ |
27260156 |
HT29 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.36972925398909595 |
[412] |
[605,592,805,584] |
7 |
hSpCas9 |
negative selection |
7248504 |
114097301 |
114097324 |
9 |
+ |
27260156 |
HT29 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.9077233126547533 |
[66] |
[294,101,78,141] |
9 |
hSpCas9 |
negative selection |
7248505 |
114094413 |
114094436 |
9 |
+ |
27260156 |
HT29 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.2715763811308257 |
[557] |
[1099,697,766,726] |
5 |
hSpCas9 |
negative selection |
7248506 |
114095261 |
114095284 |
9 |
+ |
27260156 |
HT29 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.18407888762450722 |
[424] |
[565,638,640,509] |
3 |
hSpCas9 |
negative selection |
7312760 |
114093427 |
114093450 |
9 |
- |
27260156 |
HT29 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.4536893458711022 |
[745] |
[1485,1377,1069,1075] |
8 |
hSpCas9 |
negative selection |
7312761 |
114094371 |
114094394 |
9 |
- |
27260156 |
HT29 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.6628761478295337 |
[127] |
[91,166,113,32] |
-8 |
hSpCas9 |
negative selection |
7312762 |
114097375 |
114097398 |
9 |
+ |
27260156 |
MHHES1 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.14595142778368342 |
[412] |
[505,455,479,277] |
-3 |
hSpCas9 |
negative selection |
7369755 |
114097301 |
114097324 |
9 |
+ |
27260156 |
MHHES1 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.7660397751645376 |
[66] |
[261,98,99,74] |
9 |
hSpCas9 |
negative selection |
7369756 |
114094413 |
114094436 |
9 |
+ |
27260156 |
MHHES1 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.23676196132065905 |
[557] |
[708,727,676,808] |
4 |
hSpCas9 |
negative selection |
7369757 |
114095261 |
114095284 |
9 |
+ |
27260156 |
MHHES1 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.09410721152778775 |
[424] |
[692,407,452,291] |
-2 |
hSpCas9 |
negative selection |
7434011 |
114093427 |
114093450 |
9 |
- |
27260156 |
MHHES1 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.30535236741526495 |
[745] |
[1144,1109,1098,841] |
5 |
hSpCas9 |
negative selection |
7434012 |
114094371 |
114094394 |
9 |
- |
27260156 |
MHHES1 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.687802460810141 |
[127] |
[290,340,199,132] |
9 |
hSpCas9 |
negative selection |
7434013 |
114097375 |
114097398 |
9 |
+ |
27260156 |
MEWO |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.1825852851602333 |
[412] |
[475,379,466] |
4 |
hSpCas9 |
negative selection |
7491006 |
114097301 |
114097324 |
9 |
+ |
27260156 |
MEWO |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.5113729210809383 |
[66] |
[150,82,45] |
9 |
hSpCas9 |
negative selection |
7491007 |
114094413 |
114094436 |
9 |
+ |
27260156 |
MEWO |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.051097872688089435 |
[557] |
[640,514,485] |
1 |
hSpCas9 |
negative selection |
7491008 |
114095261 |
114095284 |
9 |
+ |
27260156 |
MEWO |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.27592546187855094 |
[424] |
[415,346,238] |
-6 |
hSpCas9 |
negative selection |
7555262 |
114093427 |
114093450 |
9 |
- |
27260156 |
MEWO |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.18567563875525106 |
[745] |
[826,716,843] |
4 |
hSpCas9 |
negative selection |
7555263 |
114094371 |
114094394 |
9 |
- |
27260156 |
MEWO |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.011726573570762344 |
[127] |
[147,114,98] |
0 |
hSpCas9 |
negative selection |
7555264 |
114097375 |
114097398 |
9 |
+ |
27260156 |
LNCAPCLONEFGC |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.29554068381042775 |
[412] |
[436,457,432,504] |
4 |
hSpCas9 |
negative selection |
7612257 |
114097301 |
114097324 |
9 |
+ |
27260156 |
LNCAPCLONEFGC |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.0462148792698855 |
[66] |
[68,162,132,135] |
9 |
hSpCas9 |
negative selection |
7612258 |
114094413 |
114094436 |
9 |
+ |
27260156 |
LNCAPCLONEFGC |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.23177388320454964 |
[557] |
[627,539,635,578] |
3 |
hSpCas9 |
negative selection |
7612259 |
114095261 |
114095284 |
9 |
+ |
27260156 |
LNCAPCLONEFGC |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.052066398072013756 |
[424] |
[280,354,442,528] |
0 |
hSpCas9 |
negative selection |
7676513 |
114093427 |
114093450 |
9 |
- |
27260156 |
LNCAPCLONEFGC |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.6606187492277078 |
[745] |
[987,945,1001,1335] |
9 |
hSpCas9 |
negative selection |
7676514 |
114094371 |
114094394 |
9 |
- |
27260156 |
LNCAPCLONEFGC |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.22907695807915895 |
[127] |
[113,161,93,165] |
3 |
hSpCas9 |
negative selection |
7676515 |
114097375 |
114097398 |
9 |
+ |
27260156 |
PANC0327 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.10907112419392509 |
[412] |
[286,410,535,337] |
1 |
hSpCas9 |
negative selection |
7733508 |
114097301 |
114097324 |
9 |
+ |
27260156 |
PANC0327 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.7051301716964793 |
[66] |
[134,106,119,27] |
8 |
hSpCas9 |
negative selection |
7733509 |
114094413 |
114094436 |
9 |
+ |
27260156 |
PANC0327 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.11748068736847159 |
[557] |
[718,643,500,287] |
1 |
hSpCas9 |
negative selection |
7733510 |
114095261 |
114095284 |
9 |
+ |
27260156 |
PANC0327 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.45401070286057443 |
[424] |
[569,230,699,608] |
6 |
hSpCas9 |
negative selection |
7797764 |
114093427 |
114093450 |
9 |
- |
27260156 |
PANC0327 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.8071661834587103 |
[745] |
[955,1066,1222,1386] |
9 |
hSpCas9 |
negative selection |
7797765 |
114094371 |
114094394 |
9 |
- |
27260156 |
PANC0327 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.07343396616319375 |
[127] |
[185,104,166,27] |
1 |
hSpCas9 |
negative selection |
7797766 |
114097375 |
114097398 |
9 |
+ |
27260156 |
NCIH2009 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.47779935004972407 |
[412] |
[693,1172,513] |
6 |
hSpCas9 |
negative selection |
7854759 |
114097301 |
114097324 |
9 |
+ |
27260156 |
NCIH2009 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.2444869001224133 |
[66] |
[230,211,223] |
9 |
hSpCas9 |
negative selection |
7854760 |
114094413 |
114094436 |
9 |
+ |
27260156 |
NCIH2009 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.24979966267376277 |
[557] |
[1189,617,1028] |
3 |
hSpCas9 |
negative selection |
7854761 |
114095261 |
114095284 |
9 |
+ |
27260156 |
NCIH2009 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.3460489549081397 |
[424] |
[749,278,430] |
-5 |
hSpCas9 |
negative selection |
7919015 |
114093427 |
114093450 |
9 |
- |
27260156 |
NCIH2009 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.598779023695069 |
[745] |
[1697,1596,1460] |
8 |
hSpCas9 |
negative selection |
7919016 |
114094371 |
114094394 |
9 |
- |
27260156 |
NCIH2009 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.3550113715305858 |
[127] |
[320,230,151] |
5 |
hSpCas9 |
negative selection |
7919017 |
114097375 |
114097398 |
9 |
+ |
27260156 |
NCIH1373 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.44035726811268155 |
[412] |
[494,844,614,131] |
4 |
hSpCas9 |
negative selection |
7976010 |
114097301 |
114097324 |
9 |
+ |
27260156 |
NCIH1373 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.8322296567368552 |
[66] |
[314,522,89,29] |
9 |
hSpCas9 |
negative selection |
7976011 |
114094413 |
114094436 |
9 |
+ |
27260156 |
NCIH1373 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
-0.676317355203778 |
[557] |
[461,353,356,106] |
-6 |
hSpCas9 |
negative selection |
7976012 |
114095261 |
114095284 |
9 |
+ |
27260156 |
NCIH1373 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.5783675807924187 |
[424] |
[387,252,355,76] |
-5 |
hSpCas9 |
negative selection |
8040266 |
114093427 |
114093450 |
9 |
- |
27260156 |
NCIH1373 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.6478227216945851 |
[745] |
[1498,968,1332,396] |
6 |
hSpCas9 |
negative selection |
8040267 |
114094371 |
114094394 |
9 |
- |
27260156 |
NCIH1373 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.10320301831167611 |
[127] |
[67,81,202,68] |
1 |
hSpCas9 |
negative selection |
8040268 |
114097375 |
114097398 |
9 |
+ |
27260156 |
PATU8902 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.2791757263161333 |
[412] |
[286,663,354,639] |
-3 |
hSpCas9 |
negative selection |
8097261 |
114097301 |
114097324 |
9 |
+ |
27260156 |
PATU8902 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.777519794239963 |
[66] |
[108,200,216,88] |
7 |
hSpCas9 |
negative selection |
8097262 |
114094413 |
114094436 |
9 |
+ |
27260156 |
PATU8902 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.2539836031719508 |
[557] |
[1264,696,721,1081] |
2 |
hSpCas9 |
negative selection |
8097263 |
114095261 |
114095284 |
9 |
+ |
27260156 |
PATU8902 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.030214286558759337 |
[424] |
[706,598,442,717] |
0 |
hSpCas9 |
negative selection |
8161517 |
114093427 |
114093450 |
9 |
- |
27260156 |
PATU8902 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.6881496148605726 |
[745] |
[1744,1982,1114,2026] |
7 |
hSpCas9 |
negative selection |
8161518 |
114094371 |
114094394 |
9 |
- |
27260156 |
PATU8902 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.7535367423533881 |
[127] |
[147,87,151,9] |
-6 |
hSpCas9 |
negative selection |
8161519 |
114097375 |
114097398 |
9 |
+ |
27260156 |
PANC1 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2082266236744473 |
[412] |
[460,532,355,320] |
3 |
hSpCas9 |
negative selection |
8218512 |
114097301 |
114097324 |
9 |
+ |
27260156 |
PANC1 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.126090716884333 |
[66] |
[60,86,117,212] |
9 |
hSpCas9 |
negative selection |
8218513 |
114094413 |
114094436 |
9 |
+ |
27260156 |
PANC1 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.14821918712747081 |
[557] |
[472,434,710,486] |
2 |
hSpCas9 |
negative selection |
8218514 |
114095261 |
114095284 |
9 |
+ |
27260156 |
PANC1 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.08318355632291896 |
[424] |
[330,432,410,234] |
-1 |
hSpCas9 |
negative selection |
8282768 |
114093427 |
114093450 |
9 |
- |
27260156 |
PANC1 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.458267276925469 |
[745] |
[852,1102,824,786] |
7 |
hSpCas9 |
negative selection |
8282769 |
114094371 |
114094394 |
9 |
- |
27260156 |
PANC1 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.12571606329042861 |
[127] |
[108,94,154,49] |
-2 |
hSpCas9 |
negative selection |
8282770 |
114097375 |
114097398 |
9 |
+ |
27260156 |
PANC0813 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
-0.059666397177273456 |
[412] |
[408,598,374,471] |
-1 |
hSpCas9 |
negative selection |
8339763 |
114097301 |
114097324 |
9 |
+ |
27260156 |
PANC0813 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.1070778796219605 |
[66] |
[190,246,100,141] |
9 |
hSpCas9 |
negative selection |
8339764 |
114094413 |
114094436 |
9 |
+ |
27260156 |
PANC0813 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.5116025816809718 |
[557] |
[1112,906,676,1047] |
7 |
hSpCas9 |
negative selection |
8339765 |
114095261 |
114095284 |
9 |
+ |
27260156 |
PANC0813 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.02235250565550416 |
[424] |
[532,461,428,599] |
0 |
hSpCas9 |
negative selection |
8404019 |
114093427 |
114093450 |
9 |
- |
27260156 |
PANC0813 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.4698398960805368 |
[745] |
[1268,1242,1317,1037] |
7 |
hSpCas9 |
negative selection |
8404020 |
114094371 |
114094394 |
9 |
- |
27260156 |
PANC0813 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.4249095721727294 |
[127] |
[183,180,176,259] |
6 |
hSpCas9 |
negative selection |
8404021 |
114097375 |
114097398 |
9 |
+ |
27260156 |
RDES |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.21593249657410382 |
[412] |
[455,575,526,664] |
3 |
hSpCas9 |
negative selection |
8461014 |
114097301 |
114097324 |
9 |
+ |
27260156 |
RDES |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.8544730668720875 |
[66] |
[146,160,97,140] |
9 |
hSpCas9 |
negative selection |
8461015 |
114094413 |
114094436 |
9 |
+ |
27260156 |
RDES |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.22869480891455227 |
[557] |
[650,609,908,874] |
3 |
hSpCas9 |
negative selection |
8461016 |
114095261 |
114095284 |
9 |
+ |
27260156 |
RDES |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.18558537637126232 |
[424] |
[380,515,617,769] |
3 |
hSpCas9 |
negative selection |
8525270 |
114093427 |
114093450 |
9 |
- |
27260156 |
RDES |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.42290057398971315 |
[745] |
[1076,1071,1109,1356] |
6 |
hSpCas9 |
negative selection |
8525271 |
114094371 |
114094394 |
9 |
- |
27260156 |
RDES |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.40747591548916184 |
[127] |
[158,176,269,178] |
6 |
hSpCas9 |
negative selection |
8525272 |
114097375 |
114097398 |
9 |
+ |
27260156 |
PC3 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.0052121928081998725 |
[412] |
[293,300,691,491] |
0 |
hSpCas9 |
negative selection |
8582265 |
114097301 |
114097324 |
9 |
+ |
27260156 |
PC3 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.9643159328287427 |
[66] |
[104,132,152,133] |
9 |
hSpCas9 |
negative selection |
8582266 |
114094413 |
114094436 |
9 |
+ |
27260156 |
PC3 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.34440429698618147 |
[557] |
[468,636,1109,805] |
7 |
hSpCas9 |
negative selection |
8582267 |
114095261 |
114095284 |
9 |
+ |
27260156 |
PC3 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.057971012395227395 |
[424] |
[316,359,716,345] |
-1 |
hSpCas9 |
negative selection |
8646521 |
114093427 |
114093450 |
9 |
- |
27260156 |
PC3 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.40954348722462486 |
[745] |
[543,961,1957,974] |
8 |
hSpCas9 |
negative selection |
8646522 |
114094371 |
114094394 |
9 |
- |
27260156 |
PC3 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.13082590233329672 |
[127] |
[56,154,132,142] |
-3 |
hSpCas9 |
negative selection |
8646523 |
114097375 |
114097398 |
9 |
+ |
27260156 |
PATU8988T |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.26667979408073295 |
[412] |
[582,338,580,395] |
4 |
hSpCas9 |
negative selection |
8703516 |
114097301 |
114097324 |
9 |
+ |
27260156 |
PATU8988T |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.642001580296446 |
[66] |
[100,67,67,169] |
9 |
hSpCas9 |
negative selection |
8703517 |
114094413 |
114094436 |
9 |
+ |
27260156 |
PATU8988T |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.3117493307159358 |
[557] |
[574,664,698,742] |
5 |
hSpCas9 |
negative selection |
8703518 |
114095261 |
114095284 |
9 |
+ |
27260156 |
PATU8988T |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.21979296180761604 |
[424] |
[534,360,402,614] |
4 |
hSpCas9 |
negative selection |
8767772 |
114093427 |
114093450 |
9 |
- |
27260156 |
PATU8988T |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.6756452529551069 |
[745] |
[1028,1734,991,884] |
9 |
hSpCas9 |
negative selection |
8767773 |
114094371 |
114094394 |
9 |
- |
27260156 |
PATU8988T |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.6201889143989818 |
[127] |
[118,127,245,266] |
8 |
hSpCas9 |
negative selection |
8767774 |
114097375 |
114097398 |
9 |
+ |
27260156 |
T47D |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.2109603020570707 |
[412] |
[649,482,532,568] |
4 |
hSpCas9 |
negative selection |
8824767 |
114097301 |
114097324 |
9 |
+ |
27260156 |
T47D |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.9347454919432674 |
[66] |
[165,66,136,236] |
9 |
hSpCas9 |
negative selection |
8824768 |
114094413 |
114094436 |
9 |
+ |
27260156 |
T47D |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.010921378503593177 |
[557] |
[554,712,725,617] |
0 |
hSpCas9 |
negative selection |
8824769 |
114095261 |
114095284 |
9 |
+ |
27260156 |
T47D |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.0517340276022535 |
[424] |
[503,470,493,589] |
1 |
hSpCas9 |
negative selection |
8889023 |
114093427 |
114093450 |
9 |
- |
27260156 |
T47D |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.47658341940187654 |
[745] |
[1333,1121,1205,1181] |
8 |
hSpCas9 |
negative selection |
8889024 |
114094371 |
114094394 |
9 |
- |
27260156 |
T47D |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.008564231038839853 |
[127] |
[128,122,138,205] |
0 |
hSpCas9 |
negative selection |
8889025 |
114097375 |
114097398 |
9 |
+ |
27260156 |
SU8686 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.07249290637439697 |
[412] |
[339,375,395,660] |
1 |
hSpCas9 |
negative selection |
8946018 |
114097301 |
114097324 |
9 |
+ |
27260156 |
SU8686 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.9236740968800929 |
[66] |
[104,135,152,107] |
9 |
hSpCas9 |
negative selection |
8946019 |
114094413 |
114094436 |
9 |
+ |
27260156 |
SU8686 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
-0.03223809684741635 |
[557] |
[458,514,511,713] |
0 |
hSpCas9 |
negative selection |
8946020 |
114095261 |
114095284 |
9 |
+ |
27260156 |
SU8686 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.09758904903995044 |
[424] |
[472,442,442,436] |
1 |
hSpCas9 |
negative selection |
9010274 |
114093427 |
114093450 |
9 |
- |
27260156 |
SU8686 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.37159842607247917 |
[745] |
[930,887,792,1265] |
6 |
hSpCas9 |
negative selection |
9010275 |
114094371 |
114094394 |
9 |
- |
27260156 |
SU8686 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.44946772893001885 |
[127] |
[82,106,50,134] |
-6 |
hSpCas9 |
negative selection |
9010276 |
114097375 |
114097398 |
9 |
+ |
27260156 |
SKES1 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.06361474649912907 |
[412] |
[488,358,427,439] |
1 |
hSpCas9 |
negative selection |
9067269 |
114097301 |
114097324 |
9 |
+ |
27260156 |
SKES1 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.8862071480359732 |
[66] |
[92,86,133,164] |
9 |
hSpCas9 |
negative selection |
9067270 |
114094413 |
114094436 |
9 |
+ |
27260156 |
SKES1 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.33559806821269367 |
[557] |
[571,831,903,511] |
7 |
hSpCas9 |
negative selection |
9067271 |
114095261 |
114095284 |
9 |
+ |
27260156 |
SKES1 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.1762520518202247 |
[424] |
[448,534,502,431] |
4 |
hSpCas9 |
negative selection |
9131525 |
114093427 |
114093450 |
9 |
- |
27260156 |
SKES1 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.45058136140544947 |
[745] |
[1169,1168,970,811] |
8 |
hSpCas9 |
negative selection |
9131526 |
114094371 |
114094394 |
9 |
- |
27260156 |
SKES1 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.22919065455489385 |
[127] |
[215,143,134,114] |
5 |
hSpCas9 |
negative selection |
9131527 |
114097375 |
114097398 |
9 |
+ |
27260156 |
TOV112D |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.07863379856487718 |
[412] |
[329,499,555,368] |
1 |
hSpCas9 |
negative selection |
9188520 |
114097301 |
114097324 |
9 |
+ |
27260156 |
TOV112D |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.1344176109456023 |
[66] |
[194,205,150,57] |
9 |
hSpCas9 |
negative selection |
9188521 |
114094413 |
114094436 |
9 |
+ |
27260156 |
TOV112D |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.1566146135461247 |
[557] |
[800,696,439,586] |
3 |
hSpCas9 |
negative selection |
9188522 |
114095261 |
114095284 |
9 |
+ |
27260156 |
TOV112D |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.21156932193281125 |
[424] |
[379,808,500,352] |
4 |
hSpCas9 |
negative selection |
9252776 |
114093427 |
114093450 |
9 |
- |
27260156 |
TOV112D |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.49347828022403295 |
[745] |
[1016,1221,1037,969] |
8 |
hSpCas9 |
negative selection |
9252777 |
114094371 |
114094394 |
9 |
- |
27260156 |
TOV112D |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
0.20338488589412096 |
[127] |
[210,206,111,81] |
4 |
hSpCas9 |
negative selection |
9252778 |
114097375 |
114097398 |
9 |
+ |
27260156 |
TC71 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.14388407575855527 |
[412] |
[401,645,379,536] |
3 |
hSpCas9 |
negative selection |
9309771 |
114097301 |
114097324 |
9 |
+ |
27260156 |
TC71 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
0.5700229819919951 |
[66] |
[82,105,82,158] |
9 |
hSpCas9 |
negative selection |
9309772 |
114094413 |
114094436 |
9 |
+ |
27260156 |
TC71 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.26824517923663904 |
[557] |
[707,658,675,847] |
6 |
hSpCas9 |
negative selection |
9309773 |
114095261 |
114095284 |
9 |
+ |
27260156 |
TC71 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
0.25570683191494487 |
[424] |
[490,652,535,493] |
6 |
hSpCas9 |
negative selection |
9374027 |
114093427 |
114093450 |
9 |
- |
27260156 |
TC71 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.3347131764898239 |
[745] |
[952,1036,957,1093] |
7 |
hSpCas9 |
negative selection |
9374028 |
114094371 |
114094394 |
9 |
- |
27260156 |
TC71 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.31369074671816266 |
[127] |
[150,85,75,129] |
-7 |
hSpCas9 |
negative selection |
9374029 |
114097375 |
114097398 |
9 |
+ |
27260156 |
TC32 |
viability |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.21888135702866732 |
[412] |
[451,394,489,469] |
4 |
hSpCas9 |
negative selection |
9431022 |
114097301 |
114097324 |
9 |
+ |
27260156 |
TC32 |
viability |
CCGTTTGCAAAAGTTCCATCAGG |
KIF12 |
ENSG00000136883 |
1.093900888833202 |
[66] |
[131,121,185,100] |
9 |
hSpCas9 |
negative selection |
9431023 |
114094413 |
114094436 |
9 |
+ |
27260156 |
TC32 |
viability |
GCATCTCTGTCTCCAAACGCTGG |
KIF12 |
ENSG00000136883 |
0.38626111699424703 |
[557] |
[625,525,966,698] |
6 |
hSpCas9 |
negative selection |
9431024 |
114095261 |
114095284 |
9 |
+ |
27260156 |
TC32 |
viability |
TGAGCTTGCTGTCCCGGAAAGGG |
KIF12 |
ENSG00000136883 |
-0.037475685156796196 |
[424] |
[405,282,475,422] |
0 |
hSpCas9 |
negative selection |
9495278 |
114093427 |
114093450 |
9 |
- |
27260156 |
TC32 |
viability |
CCCACCGTGTCCCTGCTTGATGG |
KIF12 |
ENSG00000136883 |
0.5516261932039461 |
[745] |
[876,708,1443,1245] |
8 |
hSpCas9 |
negative selection |
9495279 |
114094371 |
114094394 |
9 |
- |
27260156 |
TC32 |
viability |
CCGTCGCCTGCAGTTCCAGCTGG |
KIF12 |
ENSG00000136883 |
-0.10345325708908337 |
[127] |
[102,39,64,262] |
-2 |
hSpCas9 |
negative selection |
9495280 |
114095049 |
114095072 |
9 |
- |
27869803 |
HPAFII |
viability after 27 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.12295466865225557 |
[102] |
[34,61,NaN] |
-1 |
hSpCas9 |
negative selection |
9604029 |
114095225 |
114095248 |
9 |
- |
27869803 |
HPAFII |
viability after 27 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.4265697319870066 |
[131] |
[155,40,NaN] |
3 |
hSpCas9 |
negative selection |
9604030 |
114096151 |
114096174 |
9 |
+ |
27869803 |
HPAFII |
viability after 27 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.3873661810223601 |
[706] |
[807,217,NaN] |
3 |
hSpCas9 |
negative selection |
9604031 |
114096419 |
114096442 |
9 |
+ |
27869803 |
HPAFII |
viability after 27 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.6993114667025864 |
[122] |
[50,149,NaN] |
5 |
hSpCas9 |
negative selection |
9604032 |
114097375 |
114097398 |
9 |
+ |
27869803 |
HPAFII |
viability after 27 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.267865942681495 |
[486] |
[843,426,NaN] |
9 |
hSpCas9 |
negative selection |
9604033 |
114097622 |
114097645 |
9 |
+ |
27869803 |
HPAFII |
viability after 27 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.9458787264737207 |
[475] |
[184,83,NaN] |
-6 |
hSpCas9 |
negative selection |
9604034 |
114095049 |
114095072 |
9 |
- |
27869803 |
HPAFII |
viability after 15 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
0.363001131266692 |
[102] |
[150,136,NaN] |
4 |
hSpCas9 |
negative selection |
9686478 |
114095225 |
114095248 |
9 |
- |
27869803 |
HPAFII |
viability after 15 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
0.5373028644853879 |
[131] |
[187,216,NaN] |
6 |
hSpCas9 |
negative selection |
9686479 |
114096151 |
114096174 |
9 |
+ |
27869803 |
HPAFII |
viability after 15 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.34456750825541294 |
[706] |
[976,362,NaN] |
-4 |
hSpCas9 |
negative selection |
9686480 |
114096419 |
114096442 |
9 |
+ |
27869803 |
HPAFII |
viability after 15 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
-0.16224814236627783 |
[122] |
[90,134,NaN] |
-2 |
hSpCas9 |
negative selection |
9686481 |
114097375 |
114097398 |
9 |
+ |
27869803 |
HPAFII |
viability after 15 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.259003404196719 |
[486] |
[1666,994,NaN] |
9 |
hSpCas9 |
negative selection |
9686482 |
114097622 |
114097645 |
9 |
+ |
27869803 |
HPAFII |
viability after 15 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.33685032348212474 |
[475] |
[536,322,NaN] |
-4 |
hSpCas9 |
negative selection |
9686483 |
114095049 |
114095072 |
9 |
- |
27869803 |
ASPC1 |
viability after 36 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
0.8571178080747168 |
[198] |
[53,0,273] |
8 |
hSpCas9 |
negative selection |
9768927 |
114095225 |
114095248 |
9 |
- |
27869803 |
ASPC1 |
viability after 36 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.39756671884144207 |
[623] |
[171,255,86] |
-4 |
hSpCas9 |
negative selection |
9768928 |
114096151 |
114096174 |
9 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.1795024924425428 |
[2043] |
[856,704,846] |
1 |
hSpCas9 |
negative selection |
9768929 |
114096419 |
114096442 |
9 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
-1.5168819038215537 |
[388] |
[78,50,21] |
-8 |
hSpCas9 |
negative selection |
9768930 |
114097375 |
114097398 |
9 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.06550825777886016 |
[1513] |
[579,623,471] |
0 |
hSpCas9 |
negative selection |
9768931 |
114097622 |
114097645 |
9 |
+ |
27869803 |
ASPC1 |
viability after 36 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
0.9165510116976043 |
[1154] |
[706,925,659] |
8 |
hSpCas9 |
negative selection |
9768932 |
114095049 |
114095072 |
9 |
- |
27869803 |
PATU8988S |
viability after 35 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-1.3792730415422605 |
[241] |
[22,51,NaN] |
-8 |
hSpCas9 |
negative selection |
9851376 |
114095225 |
114095248 |
9 |
- |
27869803 |
PATU8988S |
viability after 35 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.6528081516881237 |
[415] |
[134,77,NaN] |
-6 |
hSpCas9 |
negative selection |
9851377 |
114096151 |
114096174 |
9 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.40174743904513344 |
[1841] |
[1016,942,NaN] |
4 |
hSpCas9 |
negative selection |
9851378 |
114096419 |
114096442 |
9 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.8721426939062016 |
[252] |
[189,182,NaN] |
8 |
hSpCas9 |
negative selection |
9851379 |
114097375 |
114097398 |
9 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.524712243478483 |
[1268] |
[856,612,NaN] |
6 |
hSpCas9 |
negative selection |
9851380 |
114097622 |
114097645 |
9 |
+ |
27869803 |
PATU8988S |
viability after 35 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.4398236260056787 |
[1043] |
[301,317,NaN] |
-4 |
hSpCas9 |
negative selection |
9851381 |
114095049 |
114095072 |
9 |
- |
27869803 |
PATU8988S |
viability after 31 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.920997396092939 |
[241] |
[68,27,NaN] |
-7 |
hSpCas9 |
negative selection |
9933825 |
114095225 |
114095248 |
9 |
- |
27869803 |
PATU8988S |
viability after 31 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.3014768150681906 |
[415] |
[116,156,NaN] |
-3 |
hSpCas9 |
negative selection |
9933826 |
114096151 |
114096174 |
9 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.3049203291578122 |
[1841] |
[843,987,NaN] |
4 |
hSpCas9 |
negative selection |
9933827 |
114096419 |
114096442 |
9 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.3763221329465102 |
[252] |
[71,205,NaN] |
4 |
hSpCas9 |
negative selection |
9933828 |
114097375 |
114097398 |
9 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
0.36995257104907364 |
[1268] |
[634,677,NaN] |
4 |
hSpCas9 |
negative selection |
9933829 |
114097622 |
114097645 |
9 |
+ |
27869803 |
PATU8988S |
viability after 31 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.8969638504073913 |
[1043] |
[190,264,NaN] |
-7 |
hSpCas9 |
negative selection |
9933830 |
114095049 |
114095072 |
9 |
- |
27869803 |
HPAFII |
viability after 35 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-0.6889914122915932 |
[102] |
[13,52,NaN] |
-4 |
hSpCas9 |
negative selection |
10016274 |
114095225 |
114095248 |
9 |
- |
27869803 |
HPAFII |
viability after 35 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.6031331688267665 |
[131] |
[27,61,NaN] |
-4 |
hSpCas9 |
negative selection |
10016275 |
114096151 |
114096174 |
9 |
+ |
27869803 |
HPAFII |
viability after 35 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.6658274685640566 |
[706] |
[929,159,NaN] |
4 |
hSpCas9 |
negative selection |
10016276 |
114096419 |
114096442 |
9 |
+ |
27869803 |
HPAFII |
viability after 35 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
1.341332292066418 |
[122] |
[66,259,NaN] |
8 |
hSpCas9 |
negative selection |
10016277 |
114097375 |
114097398 |
9 |
+ |
27869803 |
HPAFII |
viability after 35 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.5805275843477062 |
[486] |
[861,596,NaN] |
9 |
hSpCas9 |
negative selection |
10016278 |
114097622 |
114097645 |
9 |
+ |
27869803 |
HPAFII |
viability after 35 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-0.6214538427236175 |
[475] |
[134,180,NaN] |
-4 |
hSpCas9 |
negative selection |
10016279 |
114095049 |
114095072 |
9 |
- |
27869803 |
HPAFII |
viability after 31 days |
ATATGCAAGCCGAGCTCAGCGGG |
KIF12 |
ENSG00000136883 |
-1.621016811287038 |
[102] |
[2,35,NaN] |
-7 |
hSpCas9 |
negative selection |
10098723 |
114095225 |
114095248 |
9 |
- |
27869803 |
HPAFII |
viability after 31 days |
AGACTCACTGGGAGGGCGCGGGG |
KIF12 |
ENSG00000136883 |
-0.5279280478612696 |
[131] |
[70,29,NaN] |
-4 |
hSpCas9 |
negative selection |
10098724 |
114096151 |
114096174 |
9 |
+ |
27869803 |
HPAFII |
viability after 31 days |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.37160376971466214 |
[706] |
[844,151,NaN] |
2 |
hSpCas9 |
negative selection |
10098725 |
114096419 |
114096442 |
9 |
+ |
27869803 |
HPAFII |
viability after 31 days |
CATGGCTTCGGCTGGAGGCCTGG |
KIF12 |
ENSG00000136883 |
0.9987089316219183 |
[122] |
[35,248,NaN] |
7 |
hSpCas9 |
negative selection |
10098726 |
114097375 |
114097398 |
9 |
+ |
27869803 |
HPAFII |
viability after 31 days |
CGAGTCTTGTTCCAGCGAACAGG |
KIF12 |
ENSG00000136883 |
1.4111070933223235 |
[486] |
[823,620,NaN] |
9 |
hSpCas9 |
negative selection |
10098727 |
114097622 |
114097645 |
9 |
+ |
27869803 |
HPAFII |
viability after 31 days |
CTCCAGATAAGAGGCGCGAAGGG |
KIF12 |
ENSG00000136883 |
-1.2408117013745863 |
[475] |
[124,99,NaN] |
-6 |
hSpCas9 |
negative selection |
10098728 |
114096151 |
114096174 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.25794495468912665 |
[231] |
[325] |
2 |
hSpCas9 |
negative selection |
10179470 |
114092393 |
114092416 |
9 |
- |
28162770 |
P31FUJ |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
-0.6886459200811081 |
[250] |
[182] |
-5 |
hSpCas9 |
negative selection |
10179471 |
114097670 |
114097693 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
-0.010409783077930612 |
[77] |
[90] |
0 |
hSpCas9 |
negative selection |
10179472 |
114096101 |
114096124 |
9 |
- |
28162770 |
P31FUJ |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.5165951704149698 |
[83] |
[68] |
-4 |
hSpCas9 |
negative selection |
10179473 |
114095082 |
114095105 |
9 |
+ |
28162770 |
P31FUJ |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.44108055261275825 |
[387] |
[618] |
5 |
hSpCas9 |
negative selection |
10179474 |
114094398 |
114094421 |
9 |
- |
28162770 |
P31FUJ |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
-0.7064035961878307 |
[242] |
[174] |
-5 |
hSpCas9 |
negative selection |
10179475 |
114094371 |
114094394 |
9 |
+ |
28162770 |
P31FUJ |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
0.29557676794041043 |
[51] |
[74] |
3 |
hSpCas9 |
negative selection |
10179476 |
114093426 |
114093449 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.45685767497347085 |
[216] |
[349] |
5 |
hSpCas9 |
negative selection |
10179477 |
114093305 |
114093328 |
9 |
+ |
28162770 |
P31FUJ |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.262964174924631 |
[144] |
[70] |
-7 |
hSpCas9 |
negative selection |
10179478 |
114093292 |
114093315 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-0.8326226638626479 |
[243] |
[160] |
-6 |
hSpCas9 |
negative selection |
10179479 |
114096151 |
114096174 |
9 |
+ |
28162770 |
TF1 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[112] |
1 |
hSpCas9 |
negative selection |
10348836 |
114092393 |
114092416 |
9 |
- |
28162770 |
TF1 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[189] |
1 |
hSpCas9 |
negative selection |
10348837 |
114097670 |
114097693 |
9 |
+ |
28162770 |
TF1 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[52] |
1 |
hSpCas9 |
negative selection |
10348838 |
114096101 |
114096124 |
9 |
- |
28162770 |
TF1 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[23] |
1 |
hSpCas9 |
negative selection |
10348839 |
114095082 |
114095105 |
9 |
+ |
28162770 |
TF1 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[262] |
1 |
hSpCas9 |
negative selection |
10348840 |
114094398 |
114094421 |
9 |
- |
28162770 |
TF1 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[97] |
1 |
hSpCas9 |
negative selection |
10348841 |
114094371 |
114094394 |
9 |
+ |
28162770 |
TF1 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[65] |
1 |
hSpCas9 |
negative selection |
10348842 |
114093426 |
114093449 |
9 |
+ |
28162770 |
TF1 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[266] |
1 |
hSpCas9 |
negative selection |
10348843 |
114093305 |
114093328 |
9 |
+ |
28162770 |
TF1 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[11] |
1 |
hSpCas9 |
negative selection |
10348844 |
114093292 |
114093315 |
9 |
+ |
28162770 |
TF1 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
NaN |
[NaN] |
[175] |
1 |
hSpCas9 |
negative selection |
10348845 |
114096151 |
114096174 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.00035538737484541727 |
[81] |
[144] |
0 |
hSpCas9 |
negative selection |
10518202 |
114092393 |
114092416 |
9 |
- |
28162770 |
SKM1 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
-0.9393586486601643 |
[63] |
[58] |
-6 |
hSpCas9 |
negative selection |
10518203 |
114097670 |
114097693 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
-0.0009718390673247868 |
[29] |
[52] |
0 |
hSpCas9 |
negative selection |
10518204 |
114096101 |
114096124 |
9 |
- |
28162770 |
SKM1 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.06992921146559095 |
[18] |
[31] |
0 |
hSpCas9 |
negative selection |
10518205 |
114095082 |
114095105 |
9 |
+ |
28162770 |
SKM1 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.28633092376606784 |
[108] |
[234] |
2 |
hSpCas9 |
negative selection |
10518206 |
114094398 |
114094421 |
9 |
- |
28162770 |
SKM1 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.4828528835064155 |
[67] |
[167] |
5 |
hSpCas9 |
negative selection |
10518207 |
114094371 |
114094394 |
9 |
+ |
28162770 |
SKM1 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-1.143929792909368 |
[9] |
[7] |
-7 |
hSpCas9 |
negative selection |
10518208 |
114093426 |
114093449 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
-0.1339457043367458 |
[53] |
[86] |
-1 |
hSpCas9 |
negative selection |
10518209 |
114093305 |
114093328 |
9 |
+ |
28162770 |
SKM1 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.121561979880913 |
[31] |
[25] |
-7 |
hSpCas9 |
negative selection |
10518210 |
114093292 |
114093315 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-1.1724989451061387 |
[50] |
[39] |
-7 |
hSpCas9 |
negative selection |
10518211 |
114096151 |
114096174 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.00035538737484541727 |
[81] |
[144] |
0 |
hSpCas9 |
negative selection |
10687568 |
114092393 |
114092416 |
9 |
- |
28162770 |
SKM1 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
-0.9393586486601643 |
[63] |
[58] |
-6 |
hSpCas9 |
negative selection |
10687569 |
114097670 |
114097693 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
-0.0009718390673247868 |
[29] |
[52] |
0 |
hSpCas9 |
negative selection |
10687570 |
114096101 |
114096124 |
9 |
- |
28162770 |
SKM1 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.06992921146559095 |
[18] |
[31] |
0 |
hSpCas9 |
negative selection |
10687571 |
114095082 |
114095105 |
9 |
+ |
28162770 |
SKM1 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.28633092376606784 |
[108] |
[234] |
2 |
hSpCas9 |
negative selection |
10687572 |
114094398 |
114094421 |
9 |
- |
28162770 |
SKM1 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.4828528835064155 |
[67] |
[167] |
5 |
hSpCas9 |
negative selection |
10687573 |
114094371 |
114094394 |
9 |
+ |
28162770 |
SKM1 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-1.143929792909368 |
[9] |
[7] |
-7 |
hSpCas9 |
negative selection |
10687574 |
114093426 |
114093449 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
-0.1339457043367458 |
[53] |
[86] |
-1 |
hSpCas9 |
negative selection |
10687575 |
114093305 |
114093328 |
9 |
+ |
28162770 |
SKM1 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.121561979880913 |
[31] |
[25] |
-7 |
hSpCas9 |
negative selection |
10687576 |
114093292 |
114093315 |
9 |
+ |
28162770 |
SKM1 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-1.1724989451061387 |
[50] |
[39] |
-7 |
hSpCas9 |
negative selection |
10687577 |
114096151 |
114096174 |
9 |
+ |
28162770 |
PL21 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.890058194482258 |
[263] |
[61] |
-6 |
hSpCas9 |
negative selection |
10856934 |
114092393 |
114092416 |
9 |
- |
28162770 |
PL21 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
1.1577043481689238 |
[137] |
[133] |
8 |
hSpCas9 |
negative selection |
10856935 |
114097670 |
114097693 |
9 |
+ |
28162770 |
PL21 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.42876398953728256 |
[98] |
[57] |
4 |
hSpCas9 |
negative selection |
10856936 |
114096101 |
114096124 |
9 |
- |
28162770 |
PL21 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
0.0463342784102847 |
[88] |
[39] |
0 |
hSpCas9 |
negative selection |
10856937 |
114095082 |
114095105 |
9 |
+ |
28162770 |
PL21 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
-0.3050956937611019 |
[439] |
[154] |
-2 |
hSpCas9 |
negative selection |
10856938 |
114094398 |
114094421 |
9 |
- |
28162770 |
PL21 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
-0.7347653572887949 |
[259] |
[67] |
-5 |
hSpCas9 |
negative selection |
10856939 |
114094371 |
114094394 |
9 |
+ |
28162770 |
PL21 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-1.0014942466803305 |
[22] |
[4] |
-6 |
hSpCas9 |
negative selection |
10856940 |
114093426 |
114093449 |
9 |
+ |
28162770 |
PL21 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.49526765003296724 |
[162] |
[99] |
4 |
hSpCas9 |
negative selection |
10856941 |
114093305 |
114093328 |
9 |
+ |
28162770 |
PL21 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.0014942466803305 |
[91] |
[19] |
-6 |
hSpCas9 |
negative selection |
10856942 |
114093292 |
114093315 |
9 |
+ |
28162770 |
PL21 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-2.6852178195695573 |
[132] |
[8] |
-9 |
hSpCas9 |
negative selection |
10856943 |
114096151 |
114096174 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.25794495468912665 |
[231] |
[325] |
2 |
hSpCas9 |
negative selection |
11026300 |
114092393 |
114092416 |
9 |
- |
28162770 |
P31FUJ |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
-0.6886459200811081 |
[250] |
[182] |
-5 |
hSpCas9 |
negative selection |
11026301 |
114097670 |
114097693 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
-0.010409783077930612 |
[77] |
[90] |
0 |
hSpCas9 |
negative selection |
11026302 |
114096101 |
114096124 |
9 |
- |
28162770 |
P31FUJ |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.5165951704149698 |
[83] |
[68] |
-4 |
hSpCas9 |
negative selection |
11026303 |
114095082 |
114095105 |
9 |
+ |
28162770 |
P31FUJ |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.44108055261275825 |
[387] |
[618] |
5 |
hSpCas9 |
negative selection |
11026304 |
114094398 |
114094421 |
9 |
- |
28162770 |
P31FUJ |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
-0.7064035961878307 |
[242] |
[174] |
-5 |
hSpCas9 |
negative selection |
11026305 |
114094371 |
114094394 |
9 |
+ |
28162770 |
P31FUJ |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
0.29557676794041043 |
[51] |
[74] |
3 |
hSpCas9 |
negative selection |
11026306 |
114093426 |
114093449 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.45685767497347085 |
[216] |
[349] |
5 |
hSpCas9 |
negative selection |
11026307 |
114093305 |
114093328 |
9 |
+ |
28162770 |
P31FUJ |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.262964174924631 |
[144] |
[70] |
-7 |
hSpCas9 |
negative selection |
11026308 |
114093292 |
114093315 |
9 |
+ |
28162770 |
P31FUJ |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-0.8326226638626479 |
[243] |
[160] |
-6 |
hSpCas9 |
negative selection |
11026309 |
114096151 |
114096174 |
9 |
+ |
28162770 |
OCIAML5 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.7303212985116277 |
[158] |
[172] |
-5 |
hSpCas9 |
negative selection |
11195666 |
114092393 |
114092416 |
9 |
- |
28162770 |
OCIAML5 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
1.2620566389099637 |
[81] |
[354] |
9 |
hSpCas9 |
negative selection |
11195667 |
114097670 |
114097693 |
9 |
+ |
28162770 |
OCIAML5 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.011871879559974596 |
[49] |
[90] |
0 |
hSpCas9 |
negative selection |
11195668 |
114096101 |
114096124 |
9 |
- |
28162770 |
OCIAML5 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
0.3975473192074753 |
[44] |
[106] |
3 |
hSpCas9 |
negative selection |
11195669 |
114095082 |
114095105 |
9 |
+ |
28162770 |
OCIAML5 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.23977229620107965 |
[212] |
[453] |
2 |
hSpCas9 |
negative selection |
11195670 |
114094398 |
114094421 |
9 |
- |
28162770 |
OCIAML5 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
-0.014716908508555476 |
[135] |
[242] |
0 |
hSpCas9 |
negative selection |
11195671 |
114094371 |
114094394 |
9 |
+ |
28162770 |
OCIAML5 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-1.3215518541652167 |
[17] |
[12] |
-6 |
hSpCas9 |
negative selection |
11195672 |
114093426 |
114093449 |
9 |
+ |
28162770 |
OCIAML5 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
1.3644252490327669 |
[104] |
[487] |
9 |
hSpCas9 |
negative selection |
11195673 |
114093305 |
114093328 |
9 |
+ |
28162770 |
OCIAML5 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-0.5962276664344072 |
[66] |
[79] |
-4 |
hSpCas9 |
negative selection |
11195674 |
114093292 |
114093315 |
9 |
+ |
28162770 |
OCIAML5 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
1.024274961384915 |
[69] |
[256] |
8 |
hSpCas9 |
negative selection |
11195675 |
114096151 |
114096174 |
9 |
+ |
28162770 |
EOL1 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.6999875135513763 |
[443] |
[379] |
6 |
hSpCas9 |
negative selection |
11365032 |
114092393 |
114092416 |
9 |
- |
28162770 |
EOL1 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
-0.15477468109087122 |
[242] |
[114] |
-1 |
hSpCas9 |
negative selection |
11365033 |
114097670 |
114097693 |
9 |
+ |
28162770 |
EOL1 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
-0.9289035650765234 |
[158] |
[43] |
-6 |
hSpCas9 |
negative selection |
11365034 |
114096101 |
114096124 |
9 |
- |
28162770 |
EOL1 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.7353767868318438 |
[157] |
[49] |
-5 |
hSpCas9 |
negative selection |
11365035 |
114095082 |
114095105 |
9 |
+ |
28162770 |
EOL1 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
-0.3242942870959993 |
[788] |
[331] |
-2 |
hSpCas9 |
negative selection |
11365036 |
114094398 |
114094421 |
9 |
- |
28162770 |
EOL1 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.6177090128061122 |
[427] |
[345] |
5 |
hSpCas9 |
negative selection |
11365037 |
114094371 |
114094394 |
9 |
+ |
28162770 |
EOL1 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-0.3292088206752486 |
[30] |
[12] |
-2 |
hSpCas9 |
negative selection |
11365038 |
114093426 |
114093449 |
9 |
+ |
28162770 |
EOL1 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
-0.1497995698895468 |
[218] |
[103] |
-1 |
hSpCas9 |
negative selection |
11365039 |
114093305 |
114093328 |
9 |
+ |
28162770 |
EOL1 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.158868236617103 |
[177] |
[41] |
-6 |
hSpCas9 |
negative selection |
11365040 |
114093292 |
114093315 |
9 |
+ |
28162770 |
EOL1 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-1.033873124678066 |
[170] |
[43] |
-6 |
hSpCas9 |
negative selection |
11365041 |
114096151 |
114096174 |
9 |
+ |
28162770 |
MOLM13 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.2833668701720209 |
[371] |
[220] |
-2 |
hSpCas9 |
negative selection |
11534398 |
114092393 |
114092416 |
9 |
- |
28162770 |
MOLM13 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
0.6421739223656352 |
[256] |
[289] |
5 |
hSpCas9 |
negative selection |
11534399 |
114097670 |
114097693 |
9 |
+ |
28162770 |
MOLM13 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.3170227159179513 |
[140] |
[126] |
2 |
hSpCas9 |
negative selection |
11534400 |
114096101 |
114096124 |
9 |
- |
28162770 |
MOLM13 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
0.8654817463640133 |
[103] |
[136] |
6 |
hSpCas9 |
negative selection |
11534401 |
114095082 |
114095105 |
9 |
+ |
28162770 |
MOLM13 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.9525941391097126 |
[570] |
[798] |
7 |
hSpCas9 |
negative selection |
11534402 |
114094398 |
114094421 |
9 |
- |
28162770 |
MOLM13 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.20802225478946795 |
[363] |
[303] |
1 |
hSpCas9 |
negative selection |
11534403 |
114094371 |
114094394 |
9 |
+ |
28162770 |
MOLM13 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-3.9915422370927187 |
[21] |
[0] |
-9 |
hSpCas9 |
negative selection |
11534404 |
114093426 |
114093449 |
9 |
+ |
28162770 |
MOLM13 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.4483932059187816 |
[297] |
[293] |
3 |
hSpCas9 |
negative selection |
11534405 |
114093305 |
114093328 |
9 |
+ |
28162770 |
MOLM13 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.7261212384220466 |
[150] |
[32] |
-7 |
hSpCas9 |
negative selection |
11534406 |
114093292 |
114093315 |
9 |
+ |
28162770 |
MOLM13 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
0.5618655297535927 |
[207] |
[221] |
4 |
hSpCas9 |
negative selection |
11534407 |
114096151 |
114096174 |
9 |
+ |
28162770 |
HEL |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.19047886876531456 |
[300] |
[219] |
1 |
hSpCas9 |
negative selection |
11703764 |
114092393 |
114092416 |
9 |
- |
28162770 |
HEL |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
0.5165978018672729 |
[214] |
[196] |
4 |
hSpCas9 |
negative selection |
11703765 |
114097670 |
114097693 |
9 |
+ |
28162770 |
HEL |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.3334107738926281 |
[113] |
[91] |
2 |
hSpCas9 |
negative selection |
11703766 |
114096101 |
114096124 |
9 |
- |
28162770 |
HEL |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.09422676216584924 |
[109] |
[65] |
0 |
hSpCas9 |
negative selection |
11703767 |
114095082 |
114095105 |
9 |
+ |
28162770 |
HEL |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.09613680497796073 |
[500] |
[342] |
0 |
hSpCas9 |
negative selection |
11703768 |
114094398 |
114094421 |
9 |
- |
28162770 |
HEL |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.4649517127850742 |
[344] |
[304] |
4 |
hSpCas9 |
negative selection |
11703769 |
114094371 |
114094394 |
9 |
+ |
28162770 |
HEL |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-0.8597615085288264 |
[16] |
[5] |
-5 |
hSpCas9 |
negative selection |
11703770 |
114093426 |
114093449 |
9 |
+ |
28162770 |
HEL |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
-0.18141133260022532 |
[215] |
[121] |
-1 |
hSpCas9 |
negative selection |
11703771 |
114093305 |
114093328 |
9 |
+ |
28162770 |
HEL |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.5426162100115612 |
[140] |
[30] |
-7 |
hSpCas9 |
negative selection |
11703772 |
114093292 |
114093315 |
9 |
+ |
28162770 |
HEL |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
0.3337885911112045 |
[165] |
[133] |
2 |
hSpCas9 |
negative selection |
11703773 |
114096151 |
114096174 |
9 |
+ |
28162770 |
MV411 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.3082627434788189 |
[208] |
[217] |
2 |
hSpCas9 |
negative selection |
11873130 |
114092393 |
114092416 |
9 |
- |
28162770 |
MV411 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
1.1770482228913774 |
[104] |
[199] |
9 |
hSpCas9 |
negative selection |
11873131 |
114097670 |
114097693 |
9 |
+ |
28162770 |
MV411 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.9172889490904444 |
[65] |
[104] |
8 |
hSpCas9 |
negative selection |
11873132 |
114096101 |
114096124 |
9 |
- |
28162770 |
MV411 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.41695941743278575 |
[83] |
[52] |
-3 |
hSpCas9 |
negative selection |
11873133 |
114095082 |
114095105 |
9 |
+ |
28162770 |
MV411 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.3496491622815092 |
[394] |
[423] |
3 |
hSpCas9 |
negative selection |
11873134 |
114094398 |
114094421 |
9 |
- |
28162770 |
MV411 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.6967449521463653 |
[207] |
[283] |
6 |
hSpCas9 |
negative selection |
11873135 |
114094371 |
114094394 |
9 |
+ |
28162770 |
MV411 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
2.0839388184998957 |
[6] |
[24] |
9 |
hSpCas9 |
negative selection |
11873136 |
114093426 |
114093449 |
9 |
+ |
28162770 |
MV411 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.42904435727272305 |
[163] |
[185] |
4 |
hSpCas9 |
negative selection |
11873137 |
114093305 |
114093328 |
9 |
+ |
28162770 |
MV411 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
0.11704091352710022 |
[80] |
[73] |
1 |
hSpCas9 |
negative selection |
11873138 |
114093292 |
114093315 |
9 |
+ |
28162770 |
MV411 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
0.1706219537319444 |
[134] |
[127] |
1 |
hSpCas9 |
negative selection |
11873139 |
114096151 |
114096174 |
9 |
+ |
28162770 |
MONOMAC1 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.7404990659937929 |
[176] |
[338] |
7 |
hSpCas9 |
negative selection |
12042496 |
114092393 |
114092416 |
9 |
- |
28162770 |
MONOMAC1 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
0.13343635696081735 |
[100] |
[126] |
1 |
hSpCas9 |
negative selection |
12042497 |
114097670 |
114097693 |
9 |
+ |
28162770 |
MONOMAC1 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.2816167515152618 |
[60] |
[84] |
3 |
hSpCas9 |
negative selection |
12042498 |
114096101 |
114096124 |
9 |
- |
28162770 |
MONOMAC1 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
0.08984430072860805 |
[49] |
[60] |
0 |
hSpCas9 |
negative selection |
12042499 |
114095082 |
114095105 |
9 |
+ |
28162770 |
MONOMAC1 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.06501979185041007 |
[245] |
[294] |
0 |
hSpCas9 |
negative selection |
12042500 |
114094398 |
114094421 |
9 |
- |
28162770 |
MONOMAC1 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
-0.06504130124956337 |
[166] |
[182] |
0 |
hSpCas9 |
negative selection |
12042501 |
114094371 |
114094394 |
9 |
+ |
28162770 |
MONOMAC1 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-2.31251406447949 |
[12] |
[2] |
-9 |
hSpCas9 |
negative selection |
12042502 |
114093426 |
114093449 |
9 |
+ |
28162770 |
MONOMAC1 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.4452004590133517 |
[106] |
[166] |
4 |
hSpCas9 |
negative selection |
12042503 |
114093305 |
114093328 |
9 |
+ |
28162770 |
MONOMAC1 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-1.4398933709557173 |
[70] |
[29] |
-8 |
hSpCas9 |
negative selection |
12042504 |
114093292 |
114093315 |
9 |
+ |
28162770 |
MONOMAC1 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
-1.5256595945209241 |
[107] |
[42] |
-8 |
hSpCas9 |
negative selection |
12042505 |
114096151 |
114096174 |
9 |
+ |
28162770 |
OCIAML2 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
-0.04741839451761731 |
[43] |
[235] |
0 |
hSpCas9 |
negative selection |
12211862 |
114092393 |
114092416 |
9 |
- |
28162770 |
OCIAML2 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
-1.2583262215292974 |
[40] |
[94] |
-7 |
hSpCas9 |
negative selection |
12211863 |
114097670 |
114097693 |
9 |
+ |
28162770 |
OCIAML2 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
0.19233518748026812 |
[14] |
[94] |
1 |
hSpCas9 |
negative selection |
12211864 |
114096101 |
114096124 |
9 |
- |
28162770 |
OCIAML2 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
-0.985202998071919 |
[14] |
[41] |
-6 |
hSpCas9 |
negative selection |
12211865 |
114095082 |
114095105 |
9 |
+ |
28162770 |
OCIAML2 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
0.261174063808266 |
[69] |
[464] |
2 |
hSpCas9 |
negative selection |
12211866 |
114094398 |
114094421 |
9 |
- |
28162770 |
OCIAML2 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.45220231423537915 |
[35] |
[272] |
4 |
hSpCas9 |
negative selection |
12211867 |
114094371 |
114094394 |
9 |
+ |
28162770 |
OCIAML2 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
1.3367250968154432 |
[2] |
[41] |
9 |
hSpCas9 |
negative selection |
12211868 |
114093426 |
114093449 |
9 |
+ |
28162770 |
OCIAML2 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.9299081043415676 |
[24] |
[263] |
8 |
hSpCas9 |
negative selection |
12211869 |
114093305 |
114093328 |
9 |
+ |
28162770 |
OCIAML2 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-2.7925579201295236 |
[24] |
[19] |
-9 |
hSpCas9 |
negative selection |
12211870 |
114093292 |
114093315 |
9 |
+ |
28162770 |
OCIAML2 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
0.4589808468664408 |
[20] |
[159] |
4 |
hSpCas9 |
negative selection |
12211871 |
114096151 |
114096174 |
9 |
+ |
28162770 |
OCIAML3 |
viability |
GCACAGCTTCCCACCAACAGGGG |
KIF12 |
ENSG00000136883 |
0.023522722853423716 |
[72] |
[223] |
0 |
hSpCas9 |
negative selection |
12381228 |
114092393 |
114092416 |
9 |
- |
28162770 |
OCIAML3 |
viability |
AGAGATGTTGACGGAGGAGGAGG |
KIF12 |
ENSG00000136883 |
0.8754776429770571 |
[51] |
[287] |
7 |
hSpCas9 |
negative selection |
12381229 |
114097670 |
114097693 |
9 |
+ |
28162770 |
OCIAML3 |
viability |
GCGGTCCAACAGCCAGGCGAAGG |
KIF12 |
ENSG00000136883 |
-0.7557587103207752 |
[32] |
[58] |
-5 |
hSpCas9 |
negative selection |
12381230 |
114096101 |
114096124 |
9 |
- |
28162770 |
OCIAML3 |
viability |
GTAGCAGCCACGGGATCCCGTGG |
KIF12 |
ENSG00000136883 |
0.43246457103702785 |
[26] |
[109] |
4 |
hSpCas9 |
negative selection |
12381231 |
114095082 |
114095105 |
9 |
+ |
28162770 |
OCIAML3 |
viability |
TGAGAGTCTCAGGAAGGCACTGG |
KIF12 |
ENSG00000136883 |
-0.004428511532637014 |
[103] |
[312] |
0 |
hSpCas9 |
negative selection |
12381232 |
114094398 |
114094421 |
9 |
- |
28162770 |
OCIAML3 |
viability |
AGAGATGCTGCAGCTCCAGGAGG |
KIF12 |
ENSG00000136883 |
0.3973792293711286 |
[41] |
[166] |
3 |
hSpCas9 |
negative selection |
12381233 |
114094371 |
114094394 |
9 |
+ |
28162770 |
OCIAML3 |
viability |
CCAGCTGGAACTGCAGGCGACGG |
KIF12 |
ENSG00000136883 |
-3.915935735211526 |
[4] |
[0] |
-9 |
hSpCas9 |
negative selection |
12381234 |
114093426 |
114093449 |
9 |
+ |
28162770 |
OCIAML3 |
viability |
GCCATCAAGCAGGGACACGGTGG |
KIF12 |
ENSG00000136883 |
0.1687419796122758 |
[60] |
[206] |
1 |
hSpCas9 |
negative selection |
12381235 |
114093305 |
114093328 |
9 |
+ |
28162770 |
OCIAML3 |
viability |
CAGGGGCAGGAGTAGAGGGGTGG |
KIF12 |
ENSG00000136883 |
-0.10046816736660169 |
[37] |
[106] |
-1 |
hSpCas9 |
negative selection |
12381236 |
114093292 |
114093315 |
9 |
+ |
28162770 |
OCIAML3 |
viability |
GCAGATGTGGCAGCAGGGGCAGG |
KIF12 |
ENSG00000136883 |
1.0382605751753498 |
[54] |
[340] |
8 |
hSpCas9 |
negative selection |
12381237 |