Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:11275
• Symbol:KLHL2
• Description:kelch like family member 2

DataSource: http://genomecrispr.dkfz.de/#!/results/KLHL2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
165305693	165305716	4	+	26472758	Jiyoye	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	-0.4589688717593359	[431]	[236]	-3	hSpCas9	negative selection	85302
165311515	165311538	4	+	26472758	Jiyoye	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-1.7786911638054606	[90]	[19]	-8	hSpCas9	negative selection	85303
165313334	165313357	4	+	26472758	Jiyoye	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.8700543017616396	[303]	[418]	6	hSpCas9	negative selection	85304
165314104	165314127	4	+	26472758	Jiyoye	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	1.1847829601694255	[48]	[83]	7	hSpCas9	negative selection	85305
165297659	165297682	4	+	26472758	Jiyoye	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.34828169245230467	[324]	[311]	2	hSpCas9	negative selection	85306
165297696	165297719	4	-	26472758	Jiyoye	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.28162293019982265	[107]	[66]	-2	hSpCas9	negative selection	85307
165299506	165299529	4	+	26472758	Jiyoye	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.2954387078695556	[82]	[50]	-2	hSpCas9	negative selection	85308
165299613	165299636	4	+	26472758	Jiyoye	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.32856554680950695	[131]	[124]	2	hSpCas9	negative selection	85309
165299647	165299670	4	-	26472758	Jiyoye	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.2578714376617788	[355]	[320]	2	hSpCas9	negative selection	85310
165310631	165310654	4	+	26472758	Jiyoye	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.061678815480106675	[215]	[169]	0	hSpCas9	negative selection	85311
165305693	165305716	4	+	26472758	KBM7	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.40589046410346874	[1088,657]	[427,626]	4	hSpCas9	negative selection	276420
165311515	165311538	4	+	26472758	KBM7	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.0897430937851662	[202,214]	[97,111]	0	hSpCas9	negative selection	276421
165313334	165313357	4	+	26472758	KBM7	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.12231661617061085	[1366,896]	[647,499]	1	hSpCas9	negative selection	276422
165314104	165314127	4	+	26472758	KBM7	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.15358550268863283	[577,485]	[302,253]	1	hSpCas9	negative selection	276423
165297659	165297682	4	+	26472758	KBM7	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.5133812039405764	[993,730]	[786,380]	5	hSpCas9	negative selection	276424
165297696	165297719	4	-	26472758	KBM7	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.4427036210529812	[350,270]	[102,109]	-4	hSpCas9	negative selection	276425
165299506	165299529	4	+	26472758	KBM7	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.23847008824496793	[401,452]	[176,167]	-2	hSpCas9	negative selection	276426
165299613	165299636	4	+	26472758	KBM7	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.21322060500698373	[544,528]	[327,262]	2	hSpCas9	negative selection	276427
165299647	165299670	4	-	26472758	KBM7	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.1692642711501744	[1309,1447]	[766,708]	1	hSpCas9	negative selection	276428
165310631	165310654	4	+	26472758	KBM7	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.4531206105770721	[752,857]	[543,506]	5	hSpCas9	negative selection	276429
165305693	165305716	4	+	26472758	Raji	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.41867310981461436	[489]	[151]	4	hSpCas9	negative selection	467538
165311515	165311538	4	+	26472758	Raji	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.6100292613712062	[170]	[25]	-5	hSpCas9	negative selection	467539
165313334	165313357	4	+	26472758	Raji	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.7344314374617704	[517]	[199]	7	hSpCas9	negative selection	467540
165314104	165314127	4	+	26472758	Raji	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	-0.3951168051555838	[203]	[35]	-3	hSpCas9	negative selection	467541
165297659	165297682	4	+	26472758	Raji	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.7653977881449838	[506]	[199]	7	hSpCas9	negative selection	467542
165297696	165297719	4	-	26472758	Raji	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.5518648125449251	[96]	[32]	5	hSpCas9	negative selection	467543
165299506	165299529	4	+	26472758	Raji	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.15180880416580017	[224]	[46]	-1	hSpCas9	negative selection	467544
165299613	165299636	4	+	26472758	Raji	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.007119411900170458	[282]	[65]	0	hSpCas9	negative selection	467545
165299647	165299670	4	-	26472758	Raji	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.7438077431277461	[614]	[238]	7	hSpCas9	negative selection	467546
165310631	165310654	4	+	26472758	Raji	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.4695691523867085	[416]	[133]	4	hSpCas9	negative selection	467547
165305693	165305716	4	+	26472758	K562	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.4553931767173107	[742]	[859]	3	hSpCas9	negative selection	658656
165311515	165311538	4	+	26472758	K562	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.32262186505744705	[159]	[107]	-2	hSpCas9	negative selection	658657
165313334	165313357	4	+	26472758	K562	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.7475294743993157	[1111]	[1575]	6	hSpCas9	negative selection	658658
165314104	165314127	4	+	26472758	K562	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.24858235260798323	[345]	[346]	2	hSpCas9	negative selection	658659
165297659	165297682	4	+	26472758	K562	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.7469190681956301	[791]	[1121]	6	hSpCas9	negative selection	658660
165297696	165297719	4	-	26472758	K562	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.1706187716123968	[207]	[155]	-1	hSpCas9	negative selection	658661
165299506	165299529	4	+	26472758	K562	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.1476819603352379	[415]	[316]	-1	hSpCas9	negative selection	658662
165299613	165299636	4	+	26472758	K562	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	1.161956567474474	[503]	[951]	8	hSpCas9	negative selection	658663
165299647	165299670	4	-	26472758	K562	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	1.1532708396082514	[979]	[1839]	8	hSpCas9	negative selection	658664
165310631	165310654	4	+	26472758	K562	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.5382760569671408	[601]	[737]	4	hSpCas9	negative selection	658665
165207858	165207881	4	+	26627737	DLD1	viability	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.16259701383769837	[645]	[134,301,241]	1	hSpCas9	negative selection	824356
165299497	165299520	4	+	26627737	DLD1	viability	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.1271975147632416	[733]	[253,226,157]	-1	hSpCas9	negative selection	824357
165310658	165310681	4	+	26627737	DLD1	viability	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.48445259363183535	[435]	[188,185,195]	5	hSpCas9	negative selection	824358
165311515	165311538	4	+	26627737	DLD1	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	1.1548764462239627	[233]	[151,190,148]	9	hSpCas9	negative selection	824359
165313339	165313362	4	+	26627737	DLD1	viability	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.5061826135304454	[424]	[130,89,63]	-5	hSpCas9	negative selection	824360
165314111	165314134	4	+	26627737	DLD1	viability	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.39617313676313504	[652]	[308,301,205]	4	hSpCas9	negative selection	824361
165207858	165207881	4	+	26627737	GBM cells	viability after 5 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	-0.4319388430521772	[526]	[246,171]	-6	hSpCas9	negative selection	906671
165299497	165299520	4	+	26627737	GBM cells	viability after 5 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.1480617414949631	[436]	[235,186]	-2	hSpCas9	negative selection	906672
165310658	165310681	4	+	26627737	GBM cells	viability after 5 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.3210061316984798	[305]	[216,192]	5	hSpCas9	negative selection	906673
165311515	165311538	4	+	26627737	GBM cells	viability after 5 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.0048708098550115375	[289]	[141,167]	0	hSpCas9	negative selection	906674
165313339	165313362	4	+	26627737	GBM cells	viability after 5 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.019402327520606444	[205]	[93,123]	0	hSpCas9	negative selection	906675
165314111	165314134	4	+	26627737	GBM cells	viability after 5 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.15394244470441532	[511]	[286,323]	2	hSpCas9	negative selection	906676
165207858	165207881	4	+	26627737	GBM cells	viability after 13 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.1527597186313392	[526]	[420,233]	2	hSpCas9	negative selection	988986
165299497	165299520	4	+	26627737	GBM cells	viability after 13 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.08967617990253185	[436]	[272,181]	-1	hSpCas9	negative selection	988987
165310658	165310681	4	+	26627737	GBM cells	viability after 13 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.3653393253752091	[305]	[241,190]	5	hSpCas9	negative selection	988988
165311515	165311538	4	+	26627737	GBM cells	viability after 13 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.17601913747800257	[289]	[190,166]	2	hSpCas9	negative selection	988989
165313339	165313362	4	+	26627737	GBM cells	viability after 13 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.026223620798958847	[205]	[106,111]	0	hSpCas9	negative selection	988990
165314111	165314134	4	+	26627737	GBM cells	viability after 13 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.5348690281893722	[511]	[316,471]	6	hSpCas9	negative selection	988991
165207858	165207881	4	+	26627737	GBM cells	viability after 21 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.2835429961411482	[526]	[383,315]	3	hSpCas9	negative selection	1071301
165299497	165299520	4	+	26627737	GBM cells	viability after 21 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.2695298682640803	[436]	[197,195]	-2	hSpCas9	negative selection	1071302
165310658	165310681	4	+	26627737	GBM cells	viability after 21 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.7070633023364419	[305]	[320,225]	7	hSpCas9	negative selection	1071303
165311515	165311538	4	+	26627737	GBM cells	viability after 21 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.5745883846880683	[289]	[254,215]	6	hSpCas9	negative selection	1071304
165313339	165313362	4	+	26627737	GBM cells	viability after 21 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.27220977713356287	[205]	[154,116]	3	hSpCas9	negative selection	1071305
165314111	165314134	4	+	26627737	GBM cells	viability after 21 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.43196292009875714	[511]	[380,369]	4	hSpCas9	negative selection	1071306
165207858	165207881	4	+	26627737	RPE1	viability after 9 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	1.3514148699890816	[869]	[563,863]	7	hSpCas9	negative selection	1153616
165299497	165299520	4	+	26627737	RPE1	viability after 9 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.3052376702595413	[1580]	[283,550]	-2	hSpCas9	negative selection	1153617
165310658	165310681	4	+	26627737	RPE1	viability after 9 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	2.116886532071922	[370]	[374,669]	9	hSpCas9	negative selection	1153618
165311515	165311538	4	+	26627737	RPE1	viability after 9 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.8019471545727039	[980]	[355,766]	5	hSpCas9	negative selection	1153619
165313339	165313362	4	+	26627737	RPE1	viability after 9 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-1.1896198466981582	[1435]	[59,373]	-7	hSpCas9	negative selection	1153620
165314111	165314134	4	+	26627737	RPE1	viability after 9 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.4122131038877632	[1551]	[746,516]	3	hSpCas9	negative selection	1153621
165207858	165207881	4	+	26627737	RPE1	viability after 12 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	1.1013046143952736	[869]	[636,357]	6	hSpCas9	negative selection	1235931
165299497	165299520	4	+	26627737	RPE1	viability after 12 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.48720022448945377	[1580]	[269,337]	-3	hSpCas9	negative selection	1235932
165310658	165310681	4	+	26627737	RPE1	viability after 12 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	1.9177252247792003	[370]	[413,336]	8	hSpCas9	negative selection	1235933
165311515	165311538	4	+	26627737	RPE1	viability after 12 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.8491782102084435	[980]	[348,607]	5	hSpCas9	negative selection	1235934
165313339	165313362	4	+	26627737	RPE1	viability after 12 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.9118464337229992	[1435]	[70,346]	-6	hSpCas9	negative selection	1235935
165314111	165314134	4	+	26627737	RPE1	viability after 12 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.6907837547604261	[1551]	[759,580]	4	hSpCas9	negative selection	1235936
165207858	165207881	4	+	26627737	RPE1	viability after 15 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.7717599203525296	[869]	[465,375]	5	hSpCas9	negative selection	1318246
165299497	165299520	4	+	26627737	RPE1	viability after 15 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.06902962632262444	[1580]	[294,552]	0	hSpCas9	negative selection	1318247
165310658	165310681	4	+	26627737	RPE1	viability after 15 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	1.704326012136989	[370]	[341,341]	8	hSpCas9	negative selection	1318248
165311515	165311538	4	+	26627737	RPE1	viability after 15 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.8374409633625035	[980]	[390,596]	5	hSpCas9	negative selection	1318249
165313339	165313362	4	+	26627737	RPE1	viability after 15 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-1.0558512756068414	[1435]	[116,270]	-6	hSpCas9	negative selection	1318250
165314111	165314134	4	+	26627737	RPE1	viability after 15 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.40984859497352244	[1551]	[736,434]	2	hSpCas9	negative selection	1318251
165207858	165207881	4	+	26627737	RPE1	viability after 18 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.9076474122607396	[869]	[511,363]	5	hSpCas9	negative selection	1400561
165299497	165299520	4	+	26627737	RPE1	viability after 18 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.3889804878907047	[1580]	[247,408]	-2	hSpCas9	negative selection	1400562
165310658	165310681	4	+	26627737	RPE1	viability after 18 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	1.779703264360537	[370]	[307,381]	8	hSpCas9	negative selection	1400563
165311515	165311538	4	+	26627737	RPE1	viability after 18 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.9682088171056265	[980]	[355,690]	6	hSpCas9	negative selection	1400564
165313339	165313362	4	+	26627737	RPE1	viability after 18 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.5754358390418224	[1435]	[159,366]	-4	hSpCas9	negative selection	1400565
165314111	165314134	4	+	26627737	RPE1	viability after 18 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.7931290244242097	[1551]	[893,545]	5	hSpCas9	negative selection	1400566
165207858	165207881	4	+	26627737	HeLa	viability after 8 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	-0.6526859837957955	[1281]	[349,425,291]	-6	hSpCas9	negative selection	1482876
165299497	165299520	4	+	26627737	HeLa	viability after 8 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.7705569033297653	[479]	[307,448,304]	6	hSpCas9	negative selection	1482877
165310658	165310681	4	+	26627737	HeLa	viability after 8 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.4071809449033313	[512]	[398,382,139]	4	hSpCas9	negative selection	1482878
165311515	165311538	4	+	26627737	HeLa	viability after 8 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.5183726812621502	[270]	[197,188,128]	4	hSpCas9	negative selection	1482879
165313339	165313362	4	+	26627737	HeLa	viability after 8 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.31612818141645294	[538]	[75,254,207]	-3	hSpCas9	negative selection	1482880
165314111	165314134	4	+	26627737	HeLa	viability after 8 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.23262012536433785	[627]	[510,216,279]	2	hSpCas9	negative selection	1482881
165207858	165207881	4	+	26627737	HeLa	viability after 12 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	-1.3594000291351496	[1281]	[289,129,209]	-8	hSpCas9	negative selection	1565191
165299497	165299520	4	+	26627737	HeLa	viability after 12 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.5493333491918179	[479]	[281,267,322]	4	hSpCas9	negative selection	1565192
165310658	165310681	4	+	26627737	HeLa	viability after 12 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.3060789689871615	[512]	[349,194,250]	2	hSpCas9	negative selection	1565193
165311515	165311538	4	+	26627737	HeLa	viability after 12 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.05929262455407813	[270]	[127,129,90]	0	hSpCas9	negative selection	1565194
165313339	165313362	4	+	26627737	HeLa	viability after 12 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.1916164360671851	[538]	[150,221,207]	-2	hSpCas9	negative selection	1565195
165314111	165314134	4	+	26627737	HeLa	viability after 12 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	-0.031508791290301486	[627]	[364,168,239]	0	hSpCas9	negative selection	1565196
165207858	165207881	4	+	26627737	HeLa	viability after 15 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	-1.711316255223005	[1281]	[137,173,166]	-9	hSpCas9	negative selection	1647506
165299497	165299520	4	+	26627737	HeLa	viability after 15 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.3175715108572963	[479]	[285,224,216]	2	hSpCas9	negative selection	1647507
165310658	165310681	4	+	26627737	HeLa	viability after 15 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.23136178065034835	[512]	[230,279,222]	2	hSpCas9	negative selection	1647508
165311515	165311538	4	+	26627737	HeLa	viability after 15 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.23004473653913327	[270]	[129,130,126]	2	hSpCas9	negative selection	1647509
165313339	165313362	4	+	26627737	HeLa	viability after 15 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.8700653101250377	[538]	[42,199,117]	-6	hSpCas9	negative selection	1647510
165314111	165314134	4	+	26627737	HeLa	viability after 15 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	-0.18595855297832592	[627]	[340,151,175]	-1	hSpCas9	negative selection	1647511
165207858	165207881	4	+	26627737	HeLa	viability after 18 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	-1.7369259897323375	[1281]	[87,142,166]	-9	hSpCas9	negative selection	1729821
165299497	165299520	4	+	26627737	HeLa	viability after 18 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.34430242477392836	[479]	[196,190,216]	3	hSpCas9	negative selection	1729822
165310658	165310681	4	+	26627737	HeLa	viability after 18 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.247392821673799	[512]	[152,240,222]	2	hSpCas9	negative selection	1729823
165311515	165311538	4	+	26627737	HeLa	viability after 18 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.20458467195209523	[270]	[83,106,126]	1	hSpCas9	negative selection	1729824
165313339	165313362	4	+	26627737	HeLa	viability after 18 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.8996228043548273	[538]	[26,161,117]	-7	hSpCas9	negative selection	1729825
165314111	165314134	4	+	26627737	HeLa	viability after 18 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	-0.11980537702878857	[627]	[241,134,175]	-1	hSpCas9	negative selection	1729826
165207858	165207881	4	+	26627737	HCT116	viability after 6 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	-0.05903262085823879	[1243]	[373,84]	0	hSpCas9	negative selection	1812136
165299497	165299520	4	+	26627737	HCT116	viability after 6 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.6507361906902769	[1184]	[166,91]	-4	hSpCas9	negative selection	1812137
165310658	165310681	4	+	26627737	HCT116	viability after 6 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	1.8565012639240668	[314]	[353,82]	8	hSpCas9	negative selection	1812138
165311515	165311538	4	+	26627737	HCT116	viability after 6 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-2.467387028942489	[941]	[29,24]	-8	hSpCas9	negative selection	1812139
165313339	165313362	4	+	26627737	HCT116	viability after 6 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-0.6459328978761921	[472]	[120,6]	-4	hSpCas9	negative selection	1812140
165314111	165314134	4	+	26627737	HCT116	viability after 6 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.23618837959888073	[1069]	[201,195]	1	hSpCas9	negative selection	1812141
165207858	165207881	4	+	26627737	HCT116	viability after 8 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.4351661344991685	[394]	[314,172,393]	4	hSpCas9	negative selection	1894451
165299497	165299520	4	+	26627737	HCT116	viability after 8 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.45421319593150544	[346]	[284,297,203]	5	hSpCas9	negative selection	1894452
165310658	165310681	4	+	26627737	HCT116	viability after 8 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	1.0596360212813702	[287]	[358,231,400]	8	hSpCas9	negative selection	1894453
165311515	165311538	4	+	26627737	HCT116	viability after 8 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.9449465944447499	[568]	[207,167,113]	-8	hSpCas9	negative selection	1894454
165313339	165313362	4	+	26627737	HCT116	viability after 8 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.6322743829902318	[198]	[178,238,92]	6	hSpCas9	negative selection	1894455
165314111	165314134	4	+	26627737	HCT116	viability after 8 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.030497663667070407	[449]	[281,200,276]	0	hSpCas9	negative selection	1894456
165207858	165207881	4	+	26627737	HCT116	viability after 9 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.03632155968396078	[1243]	[262,401]	0	hSpCas9	negative selection	1976766
165299497	165299520	4	+	26627737	HCT116	viability after 9 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-1.1436304860177668	[1184]	[164,125]	-7	hSpCas9	negative selection	1976767
165310658	165310681	4	+	26627737	HCT116	viability after 9 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.5251820068505826	[314]	[153,94]	4	hSpCas9	negative selection	1976768
165311515	165311538	4	+	26627737	HCT116	viability after 9 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-1.9827396769609544	[941]	[47,75]	-8	hSpCas9	negative selection	1976769
165313339	165313362	4	+	26627737	HCT116	viability after 9 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.5710449942969891	[472]	[276,116]	4	hSpCas9	negative selection	1976770
165314111	165314134	4	+	26627737	HCT116	viability after 9 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	1.1254130811012417	[1069]	[233,930]	7	hSpCas9	negative selection	1976771
165207858	165207881	4	+	26627737	HCT116	viability after 12 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.21383520391624544	[394]	[162,278,287]	2	hSpCas9	negative selection	2059081
165299497	165299520	4	+	26627737	HCT116	viability after 12 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.5964307400736676	[346]	[170,260,403]	5	hSpCas9	negative selection	2059082
165310658	165310681	4	+	26627737	HCT116	viability after 12 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.48791569032336435	[287]	[218,245,171]	5	hSpCas9	negative selection	2059083
165311515	165311538	4	+	26627737	HCT116	viability after 12 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.9908707424110016	[568]	[119,147,185]	-8	hSpCas9	negative selection	2059084
165313339	165313362	4	+	26627737	HCT116	viability after 12 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.7440868549979823	[198]	[113,345,74]	6	hSpCas9	negative selection	2059085
165314111	165314134	4	+	26627737	HCT116	viability after 12 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.019450203940335475	[449]	[285,279,149]	0	hSpCas9	negative selection	2059086
165207858	165207881	4	+	26627737	HCT116	viability after 15 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.13255005896315464	[394]	[255,248,241]	1	hSpCas9	negative selection	2141396
165299497	165299520	4	+	26627737	HCT116	viability after 15 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.49010698080305537	[346]	[328,263,252]	4	hSpCas9	negative selection	2141397
165310658	165310681	4	+	26627737	HCT116	viability after 15 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.7033175135195389	[287]	[394,223,204]	6	hSpCas9	negative selection	2141398
165311515	165311538	4	+	26627737	HCT116	viability after 15 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.5759950129436561	[568]	[226,164,265]	-5	hSpCas9	negative selection	2141399
165313339	165313362	4	+	26627737	HCT116	viability after 15 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.5715472383991245	[198]	[176,213,119]	5	hSpCas9	negative selection	2141400
165314111	165314134	4	+	26627737	HCT116	viability after 15 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.35112746273132567	[449]	[423,294,281]	3	hSpCas9	negative selection	2141401
165207858	165207881	4	+	26627737	HCT116	viability after 18 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.7933401293594995	[394]	[323,306,364]	6	hSpCas9	negative selection	2223711
165299497	165299520	4	+	26627737	HCT116	viability after 18 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.40774513323108086	[346]	[234,222,208]	3	hSpCas9	negative selection	2223712
165310658	165310681	4	+	26627737	HCT116	viability after 18 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.5706890233009663	[287]	[175,256,182]	5	hSpCas9	negative selection	2223713
165311515	165311538	4	+	26627737	HCT116	viability after 18 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-1.110897532557261	[568]	[106,127,147]	-7	hSpCas9	negative selection	2223714
165313339	165313362	4	+	26627737	HCT116	viability after 18 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.1915059752738586	[198]	[60,134,132]	1	hSpCas9	negative selection	2223715
165314111	165314134	4	+	26627737	HCT116	viability after 18 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.13625407692623925	[449]	[198,163,364]	1	hSpCas9	negative selection	2223716
165209916	165209939	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAATGGGAGTGGAGGCAAACAGG	KLHL2	ENSG00000109466	-0.36806330327567505	[289,287]	[15,84]	-2	dCas9-VP64	positive selection	2403716
165209828	165209851	4	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCTTGAATTAGGTTTAATCCTGG	KLHL2	ENSG00000109466	-0.895403929557621	[383,543]	[27,83]	-5	dCas9-VP64	positive selection	2403717
165209859	165209882	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGGTGTTATTTGCCATTCTGTGG	KLHL2	ENSG00000109466	1.7169258465191635	[121,447]	[27,402]	6	dCas9-VP64	positive selection	2403718
165231191	165231214	4	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATTCCAGCACTTTAG	KLHL2	ENSG00000109466	1.9829372138366936	[192,253]	[363,12]	7	dCas9-VP64	positive selection	2430044
165209916	165209939	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAATGGGAGTGGAGGCAAACAGG	KLHL2	ENSG00000109466	0.19691915878471006	[103,79]	[28,38]	1	dCas9-VP64	positive selection	2498971
165209828	165209851	4	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCTTGAATTAGGTTTAATCCTGG	KLHL2	ENSG00000109466	-0.4456860254431168	[177,132]	[55,19]	-5	dCas9-VP64	positive selection	2498972
165209859	165209882	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGGTGTTATTTGCCATTCTGTGG	KLHL2	ENSG00000109466	-0.4475499686772597	[176,394]	[77,57]	-5	dCas9-VP64	positive selection	2498973
165231191	165231214	4	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATTCCAGCACTTTAG	KLHL2	ENSG00000109466	2.0349420860207257	[143,154]	[35,352]	8	dCas9-VP64	positive selection	2525299
165297705	165297728	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCTGAACTAAATATTCCCGAGG	KLHL2	ENSG00000109466	0.13242255361860328	[3,4]	[3,3]	2	hSpCas9	positive selection	2997783
165305599	165305622	4	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCTTGTAGTTGATGGTGGTGG	KLHL2	ENSG00000109466	-0.14856642873464002	[3,3]	[3,1]	-2	hSpCas9	positive selection	2997784
165263277	165263300	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGATTCCTAAGCAGTTGACAGGG	KLHL2	ENSG00000109466	0.10945966869697468	[3,4]	[3,4]	2	hSpCas9	positive selection	2997785
165263327	165263350	4	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTGGCCTTGTTCAGAAGGTCGG	KLHL2	ENSG00000109466	-0.512976096910397	[2,1]	[1,0]	-6	hSpCas9	positive selection	2997786
165297705	165297728	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCTGAACTAAATATTCCCGAGG	KLHL2	ENSG00000109466	0.21465671628375968	[3,3]	[3,2]	4	hSpCas9	positive selection	3065641
165305599	165305622	4	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCTTGTAGTTGATGGTGGTGG	KLHL2	ENSG00000109466	0.3646888511294519	[3,3]	[4,2]	6	hSpCas9	positive selection	3065642
165263277	165263300	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGATTCCTAAGCAGTTGACAGGG	KLHL2	ENSG00000109466	0.21379267251081155	[3,3]	[3,2]	4	hSpCas9	positive selection	3065643
165263327	165263350	4	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTGGCCTTGTTCAGAAGGTCGG	KLHL2	ENSG00000109466	0.7619361692787092	[2,2]	[0,4]	9	hSpCas9	positive selection	3065644
165294385	165294408		+	24336571	A375	resistance to PLX after 7 days	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.14598304522251293	[21,21]	[17,20]	-5	hSpCas9	positive selection	3123411
165263241	165263264		+	24336571	A375	resistance to PLX after 7 days	GAAGACTTGTTGTGAATTTTTGG	KLHL2	ENSG00000109466	-0.23615692695320478	[7,12]	[9,7]	-7	hSpCas9	positive selection	3123413
165219925	165219948		+	24336571	A375	resistance to PLX after 7 days	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.16164855209128706	[11,14]	[15,13]	5	hSpCas9	positive selection	3123414
165219959	165219982		-	24336571	A375	resistance to PLX after 7 days	TTATCATCTTTTGAATCGAGAGG	KLHL2	ENSG00000109466	0.5721572550117041	[11,11]	[18,15]	9	hSpCas9	positive selection	3123415
165294385	165294408		+	24336571	A375	resistance to PLX after 14 days	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.9194968903733575	[34,23]	[5,7]	-9	hSpCas9	positive selection	3181204
165263241	165263264		+	24336571	A375	resistance to PLX after 14 days	GAAGACTTGTTGTGAATTTTTGG	KLHL2	ENSG00000109466	-0.21150976915404823	[8,11]	[2,4]	-2	hSpCas9	positive selection	3181206
165219925	165219948		+	24336571	A375	resistance to PLX after 14 days	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.18171300994995698	[16,9]	[7,5]	2	hSpCas9	positive selection	3181207
165219959	165219982		-	24336571	A375	resistance to PLX after 14 days	TTATCATCTTTTGAATCGAGAGG	KLHL2	ENSG00000109466	0.849245490918994	[14,18]	[10,16]	7	hSpCas9	positive selection	3181208
165294385	165294408		+	24336571	A375	viability after 7 days	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.28513402104846675	[27]	[21,21]	-4	hSpCas9	negative selection	3238997
165263241	165263264		+	24336571	A375	viability after 7 days	GAAGACTTGTTGTGAATTTTTGG	KLHL2	ENSG00000109466	0.02398345831508336	[10]	[7,12]	0	hSpCas9	negative selection	3238999
165219925	165219948		+	24336571	A375	viability after 7 days	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.05543543349297832	[14]	[11,14]	-1	hSpCas9	negative selection	3239000
165219959	165219982		-	24336571	A375	viability after 7 days	TTATCATCTTTTGAATCGAGAGG	KLHL2	ENSG00000109466	-0.5824160872169235	[18]	[11,11]	-7	hSpCas9	negative selection	3239001
165294385	165294408		+	24336571	A375	viability after 14 days	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.1463191576152183	[27]	[34,23]	2	hSpCas9	negative selection	3296790
165263241	165263264		+	24336571	A375	viability after 14 days	GAAGACTTGTTGTGAATTTTTGG	KLHL2	ENSG00000109466	0.059807572886808213	[10]	[8,11]	0	hSpCas9	negative selection	3296792
165219925	165219948		+	24336571	A375	viability after 14 days	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.01685637648533135	[14]	[16,9]	0	hSpCas9	negative selection	3296793
165219959	165219982		-	24336571	A375	viability after 14 days	TTATCATCTTTTGAATCGAGAGG	KLHL2	ENSG00000109466	-0.08297653377681785	[18]	[14,18]	-1	hSpCas9	negative selection	3296794
165294447	165294470	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	-0.3351308258222454	[192,192]	[0,0]	-2	hSpCas9	positive selection	3376002
165219925	165219948	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	1.3031299010589596	[61,61]	[0,0]	5	hSpCas9	positive selection	3376003
165294385	165294408	4	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	2.3187267561099785	[91,91]	[2,2]	8	hSpCas9	positive selection	3376004
165297705	165297728	4	-	26780180	HT29	viability (Avana library 4 designs)	ACCTGAACTAAATATTCCCGAGG	KLHL2	ENSG00000109466	1.83310938516563	[]	[]	7	hSpCas9	negative selection	3435223
165305598	165305621	4	+	26780180	HT29	viability (Avana library 4 designs)	GCCCTTGTAGTTGATGGTGGTGG	KLHL2	ENSG00000109466	0.144239844077987	[]	[]	0	hSpCas9	negative selection	3435224
165263277	165263300	4	-	26780180	HT29	viability (Avana library 4 designs)	GGATTCCTAAGCAGTTGACAGGG	KLHL2	ENSG00000109466	0.393538913662466	[]	[]	1	hSpCas9	negative selection	3435225
165263327	165263350	4	-	26780180	HT29	viability (Avana library 4 designs)	GTTGGCCTTGTTCAGAAGGTCGG	KLHL2	ENSG00000109466	1.95463811576351	[]	[]	7	hSpCas9	negative selection	3435226
165297705	165297728	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCTGAACTAAATATTCCCGAGG	KLHL2	ENSG00000109466	-1.37302172587401	[]	[]	-2	hSpCas9	negative selection	3522694
165263277	165263300	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATTCCTAAGCAGTTGACAGGG	KLHL2	ENSG00000109466	0.421132392124485	[]	[]	0	hSpCas9	negative selection	3522695
165305598	165305621	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCTTGTAGTTGATGGTGGTGG	KLHL2	ENSG00000109466	4.93196231052486	[]	[]	8	hSpCas9	negative selection	3522696
165263327	165263350	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTGGCCTTGTTCAGAAGGTCGG	KLHL2	ENSG00000109466	1.42785180545062	[]	[]	2	hSpCas9	negative selection	3522697
165238835	165238858	4	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAATCAATTAGCATCCTCAGGG	KLHL2	ENSG00000109466	-4.87728899816844	[]	[]	-5	hSpCas9	negative selection	3522698
165305663	165305686	4	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATGACTTTAAAGAAGAAAGGTGG	KLHL2	ENSG00000109466	-13.2792506530864	[]	[]	-8	hSpCas9	negative selection	3522699
165297705	165297728	4	-	26780180	A375	viability (Avana lentiGuide)	ACCTGAACTAAATATTCCCGAGG	KLHL2	ENSG00000109466	1.29702188897022	[]	[]	1	hSpCas9	negative selection	3631353
165263277	165263300	4	-	26780180	A375	viability (Avana lentiGuide)	GGATTCCTAAGCAGTTGACAGGG	KLHL2	ENSG00000109466	2.75991611921153	[]	[]	3	hSpCas9	negative selection	3631354
165305598	165305621	4	+	26780180	A375	viability (Avana lentiGuide)	GCCCTTGTAGTTGATGGTGGTGG	KLHL2	ENSG00000109466	1.73719731850358	[]	[]	2	hSpCas9	negative selection	3631355
165263327	165263350	4	-	26780180	A375	viability (Avana lentiGuide)	GTTGGCCTTGTTCAGAAGGTCGG	KLHL2	ENSG00000109466	1.17987974904367	[]	[]	1	hSpCas9	negative selection	3631356
165238835	165238858	4	-	26780180	A375	viability (Avana lentiGuide)	ATAATCAATTAGCATCCTCAGGG	KLHL2	ENSG00000109466	4.58083038486159	[]	[]	4	hSpCas9	negative selection	3631357
165305663	165305686	4	+	26780180	A375	viability (Avana lentiGuide)	ATGACTTTAAAGAAGAAAGGTGG	KLHL2	ENSG00000109466	-3.2759779893052	[]	[]	-6	hSpCas9	negative selection	3631358
165297705	165297728	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCTGAACTAAATATTCCCGAGG	KLHL2	ENSG00000109466	-0.2657249311210292	[6]	[5,4]	-4	hSpCas9	positive selection	3740012
165263277	165263300	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATTCCTAAGCAGTTGACAGGG	KLHL2	ENSG00000109466	-0.30718019349808595	[5]	[4,3]	-5	hSpCas9	positive selection	3740013
165305598	165305621	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCTTGTAGTTGATGGTGGTGG	KLHL2	ENSG00000109466	0.1455980791030992	[4]	[4,4]	4	hSpCas9	positive selection	3740014
165263327	165263350	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTGGCCTTGTTCAGAAGGTCGG	KLHL2	ENSG00000109466	-0.11584795186008479	[4]	[3,4]	-2	hSpCas9	positive selection	3740015
165238835	165238858	4	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAATCAATTAGCATCCTCAGGG	KLHL2	ENSG00000109466	-0.6331307179454073	[8]	[4,4]	-7	hSpCas9	positive selection	3740016
165305663	165305686	4	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGACTTTAAAGAAGAAAGGTGG	KLHL2	ENSG00000109466	-0.7126719098112556	[8]	[4,4]	-7	hSpCas9	positive selection	3740017
165297705	165297728	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCTGAACTAAATATTCCCGAGG	KLHL2	ENSG00000109466	0.1680820427175913	[6]	[6,5]	4	hSpCas9	positive selection	3848619
165263277	165263300	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATTCCTAAGCAGTTGACAGGG	KLHL2	ENSG00000109466	-0.34449258988303466	[6]	[4,3]	-4	hSpCas9	positive selection	3848620
165305598	165305621	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCTTGTAGTTGATGGTGGTGG	KLHL2	ENSG00000109466	0.12593010876253072	[5]	[5,4]	3	hSpCas9	positive selection	3848621
165263327	165263350	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTGGCCTTGTTCAGAAGGTCGG	KLHL2	ENSG00000109466	-0.7444429656424068	[4]	[1,2]	-7	hSpCas9	positive selection	3848622
165238835	165238858	4	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAATCAATTAGCATCCTCAGGG	KLHL2	ENSG00000109466	0.007673665961401524	[5]	[5,3]	0	hSpCas9	positive selection	3848623
165305663	165305686	4	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGACTTTAAAGAAGAAAGGTGG	KLHL2	ENSG00000109466	0.07977437928436246	[6]	[5,5]	1	hSpCas9	positive selection	3848624
165210133	165210156	4	+	26780180	A375	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	1.15995859958183	[]	[]	6	hSpCas9	negative selection	3954665
165210166	165210189	4	-	26780180	A375	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.731294983560757	[]	[]	2	hSpCas9	negative selection	3954666
165294385	165294408	4	+	26780180	A375	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.617007001803377	[]	[]	2	hSpCas9	negative selection	3954667
165228816	165228839	4	+	26780180	A375	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	1.43451673176066	[]	[]	8	hSpCas9	negative selection	3954668
165294447	165294470	4	+	26780180	A375	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.231463197862261	[]	[]	0	hSpCas9	negative selection	3954669
165219925	165219948	4	+	26780180	A375	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.944252034087624	[]	[]	4	hSpCas9	negative selection	3954670
165210133	165210156	4	+	26780180	HT29	viability (GeCKOv2 library)	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	0.414573970734086	[]	[]	1	hSpCas9	negative selection	4062631
165210166	165210189	4	-	26780180	HT29	viability (GeCKOv2 library)	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	1.23813064966433	[]	[]	6	hSpCas9	negative selection	4062632
165294385	165294408	4	+	26780180	HT29	viability (GeCKOv2 library)	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.80860360317478	[]	[]	3	hSpCas9	negative selection	4062633
165228816	165228839	4	+	26780180	HT29	viability (GeCKOv2 library)	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	0.330993224810154	[]	[]	0	hSpCas9	negative selection	4062634
165294447	165294470	4	+	26780180	HT29	viability (GeCKOv2 library)	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.795466595952553	[]	[]	3	hSpCas9	negative selection	4062635
165219925	165219948	4	+	26780180	HT29	viability (GeCKOv2 library)	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	1.65380092188856	[]	[]	8	hSpCas9	negative selection	4062636
165294385	165294408	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.054326807049538184	[4]	[3,2]	-1	hSpCas9	positive selection	4147347
165263241	165263264	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGACTTGTTGTGAATTTTTGG	KLHL2	ENSG00000109466	-0.13959421806042166	[3]	[1,1]	-3	hSpCas9	positive selection	4147349
165219925	165219948	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.045446787081656434	[3]	[1,2]	-1	hSpCas9	positive selection	4147350
165219959	165219982	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATCATCTTTTGAATCGAGAGG	KLHL2	ENSG00000109466	0.32856470439447555	[3]	[2,3]	7	hSpCas9	positive selection	4147351
165294385	165294408	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.9775490183444605	[4]	[4,2,5,3]	6	hSpCas9	positive selection	4211369
165263241	165263264	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGACTTGTTGTGAATTTTTGG	KLHL2	ENSG00000109466	0.5313344358159555	[3]	[3,3,3,0]	3	hSpCas9	positive selection	4211371
165219925	165219948	4	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.46215796124933084	[3]	[5,0,3,0]	3	hSpCas9	positive selection	4211372
165219959	165219982	4	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATCATCTTTTGAATCGAGAGG	KLHL2	ENSG00000109466	0.7335668211043714	[2]	[2,3,4,0]	5	hSpCas9	positive selection	4211373
165210133	165210156	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	0.2088600034591639	[4]	[3,4]	4	hSpCas9	positive selection	4278822
165228816	165228839	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.11180999457394558	[4]	[3,2]	-2	hSpCas9	positive selection	4278823
165210166	165210189	4	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.4700884253686636	[1]	[1,0]	-8	hSpCas9	positive selection	4278824
165294447	165294470	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.20088891703387657	[2]	[3,1]	4	hSpCas9	positive selection	4343078
165219925	165219948	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.1318375351619915	[2]	[1,1]	-3	hSpCas9	positive selection	4343079
165294385	165294408	4	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.22208835989951092	[2]	[3,2]	4	hSpCas9	positive selection	4343080
165263281	165263303	4	+	27760321	OCIAML3	viability	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.061944426140789016	[470,440]	[241,471]	0	hSpCas9	negative selection	4412626
165297611	165297633	4	+	27760321	OCIAML3	viability	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	0.42161460733265965	[55,60]	[62,59]	5	hSpCas9	negative selection	4412627
165297627	165297649	4	+	27760321	OCIAML3	viability	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.4193489541492521	[278,206]	[214,299]	5	hSpCas9	negative selection	4412628
165297660	165297682	4	+	27760321	OCIAML3	viability	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	-0.06432689774206907	[558,588]	[333,558]	0	hSpCas9	negative selection	4412629
165297696	165297718	4	-	27760321	OCIAML3	viability	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.5491546339839309	[168,146]	[139,232]	6	hSpCas9	negative selection	4412630
165263281	165263303	4	+	27760321	OCIAML2	viability	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	0.09279117583105136	[470,440]	[406,375]	1	hSpCas9	negative selection	4496089
165297611	165297633	4	+	27760321	OCIAML2	viability	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	0.5671000608573644	[55,60]	[67,73]	7	hSpCas9	negative selection	4496090
165297627	165297649	4	+	27760321	OCIAML2	viability	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.6646909335251143	[278,206]	[225,417]	8	hSpCas9	negative selection	4496091
165297660	165297682	4	+	27760321	OCIAML2	viability	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.41859607674241717	[558,588]	[557,710]	6	hSpCas9	negative selection	4496092
165297696	165297718	4	-	27760321	OCIAML2	viability	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.2230250957734876	[168,146]	[153,141]	3	hSpCas9	negative selection	4496093
165263281	165263303	4	+	27760321	MV411	viability	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.8583943772537944	[470,440]	[10,398]	-5	hSpCas9	negative selection	4579552
165297611	165297633	4	+	27760321	MV411	viability	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-1.3367123814483706	[55,60]	[0,36]	-7	hSpCas9	negative selection	4579553
165297627	165297649	4	+	27760321	MV411	viability	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.4705680314281614	[278,206]	[250,173]	3	hSpCas9	negative selection	4579554
165297660	165297682	4	+	27760321	MV411	viability	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.6217252527886781	[558,588]	[589,579]	4	hSpCas9	negative selection	4579555
165297696	165297718	4	-	27760321	MV411	viability	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.14051473983811125	[168,146]	[43,169]	-1	hSpCas9	negative selection	4579556
165263281	165263303	4	+	27760321	HL60	viability	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	0.021739400068307616	[470,440]	[340,417]	0	hSpCas9	negative selection	4663015
165297611	165297633	4	+	27760321	HL60	viability	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-0.5259314215005446	[55,60]	[13,53]	-5	hSpCas9	negative selection	4663016
165297627	165297649	4	+	27760321	HL60	viability	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.1407433554941825	[278,206]	[196,237]	1	hSpCas9	negative selection	4663017
165297660	165297682	4	+	27760321	HL60	viability	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.4266576853532189	[558,588]	[638,627]	5	hSpCas9	negative selection	4663018
165297696	165297718	4	-	27760321	HL60	viability	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.283311735427348	[168,146]	[162,149]	3	hSpCas9	negative selection	4663019
165263281	165263303	4	+	27760321	HT1080	viability	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.25710399163756104	[440,343]	[179,76]	-1	hSpCas9	negative selection	4746478
165297611	165297633	4	+	27760321	HT1080	viability	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-1.802682185233071	[60,47]	[10,0]	-6	hSpCas9	negative selection	4746479
165297627	165297649	4	+	27760321	HT1080	viability	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	1.0083930233563165	[206,161]	[39,265]	5	hSpCas9	negative selection	4746480
165297660	165297682	4	+	27760321	HT1080	viability	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	-0.11982918173577722	[588,459]	[166,219]	0	hSpCas9	negative selection	4746481
165297696	165297718	4	-	27760321	HT1080	viability	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-2.400573799413761	[146,114]	[17,0]	-7	hSpCas9	negative selection	4746482
165263281	165263303	4	+	27760321	HT29	viability after 7 days	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.34131905288940667	[440,343]	[347,307,526]	-5	hSpCas9	negative selection	4829941
165297611	165297633	4	+	27760321	HT29	viability after 7 days	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-0.9768174628175568	[60,47]	[24,66,13]	-8	hSpCas9	negative selection	4829942
165297627	165297649	4	+	27760321	HT29	viability after 7 days	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.5471510700846633	[206,161]	[318,287,425]	8	hSpCas9	negative selection	4829943
165297660	165297682	4	+	27760321	HT29	viability after 7 days	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.062220055096271154	[588,459]	[665,771,668]	0	hSpCas9	negative selection	4829944
165297696	165297718	4	-	27760321	HT29	viability after 7 days	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.002181194428619193	[146,114]	[136,165,195]	0	hSpCas9	negative selection	4829945
165263281	165263303	4	+	27760321	HT29	viability after 25 days	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.18411346241371898	[440,343]	[265,383,558]	-2	hSpCas9	negative selection	4913404
165297611	165297633	4	+	27760321	HT29	viability after 25 days	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-0.969846667413008	[60,47]	[16,58,18]	-6	hSpCas9	negative selection	4913405
165297627	165297649	4	+	27760321	HT29	viability after 25 days	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.46271580769478615	[206,161]	[192,424,255]	5	hSpCas9	negative selection	4913406
165297660	165297682	4	+	27760321	HT29	viability after 25 days	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.37950045989173653	[588,459]	[761,946,612]	4	hSpCas9	negative selection	4913407
165297696	165297718	4	-	27760321	HT29	viability after 25 days	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.6892862993571122	[146,114]	[403,151,147]	7	hSpCas9	negative selection	4913408
165263281	165263303	4	+	27760321	HT29	viability after 22 days	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	0.13405527279015467	[440,343]	[334,469,694]	1	hSpCas9	negative selection	4996867
165297611	165297633	4	+	27760321	HT29	viability after 22 days	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-0.8616221633924028	[60,47]	[27,67,7]	-6	hSpCas9	negative selection	4996868
165297627	165297649	4	+	27760321	HT29	viability after 22 days	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.1574413528391283	[206,161]	[124,334,256]	1	hSpCas9	negative selection	4996869
165297660	165297682	4	+	27760321	HT29	viability after 22 days	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.2807491429482344	[588,459]	[649,848,712]	3	hSpCas9	negative selection	4996870
165297696	165297718	4	-	27760321	HT29	viability after 22 days	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.09290542464497542	[146,114]	[237,139,103]	0	hSpCas9	negative selection	4996871
165263281	165263303	4	+	27760321	HT29	viability after 19 days	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.4114920289264539	[440,343]	[295,162,540]	-4	hSpCas9	negative selection	5080330
165297611	165297633	4	+	27760321	HT29	viability after 19 days	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-1.8258812715321446	[60,47]	[44,2,7]	-8	hSpCas9	negative selection	5080331
165297627	165297649	4	+	27760321	HT29	viability after 19 days	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.6140795981853653	[206,161]	[246,527,190]	6	hSpCas9	negative selection	5080332
165297660	165297682	4	+	27760321	HT29	viability after 19 days	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.31664290797760497	[588,459]	[552,1013,656]	3	hSpCas9	negative selection	5080333
165297696	165297718	4	-	27760321	HT29	viability after 19 days	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.255221166861731	[146,114]	[191,78,112]	-2	hSpCas9	negative selection	5080334
165263281	165263303	4	+	27760321	HT29	viability after 16 days	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.03835583470614776	[440,343]	[368,357,551]	0	hSpCas9	negative selection	5163793
165297611	165297633	4	+	27760321	HT29	viability after 16 days	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	0.40387214250649306	[60,47]	[163,3,83]	4	hSpCas9	negative selection	5163794
165297627	165297649	4	+	27760321	HT29	viability after 16 days	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.7798227123589644	[206,161]	[340,471,245]	8	hSpCas9	negative selection	5163795
165297660	165297682	4	+	27760321	HT29	viability after 16 days	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.1216490454853224	[588,459]	[802,593,534]	1	hSpCas9	negative selection	5163796
165297696	165297718	4	-	27760321	HT29	viability after 16 days	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.0009446669940018637	[146,114]	[167,202,68]	0	hSpCas9	negative selection	5163797
165263281	165263303	4	+	27760321	HT29	viability after 13 days	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	0.1224333980991684	[440,343]	[434,487,559]	1	hSpCas9	negative selection	5247256
165297611	165297633	4	+	27760321	HT29	viability after 13 days	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-1.0130935824574352	[60,47]	[24,19,47]	-7	hSpCas9	negative selection	5247257
165297627	165297649	4	+	27760321	HT29	viability after 13 days	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.7335256471087357	[206,161]	[456,398,219]	8	hSpCas9	negative selection	5247258
165297660	165297682	4	+	27760321	HT29	viability after 13 days	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.12567396841794787	[588,459]	[829,528,633]	1	hSpCas9	negative selection	5247259
165297696	165297718	4	-	27760321	HT29	viability after 13 days	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.4130566225759733	[146,114]	[99,315,191]	5	hSpCas9	negative selection	5247260
165263281	165263303	4	+	27760321	HT29	viability after 10 days	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.01522122885484288	[440,343]	[380,498,572]	0	hSpCas9	negative selection	5330719
165297611	165297633	4	+	27760321	HT29	viability after 10 days	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-0.3448042752811413	[60,47]	[51,37,69]	-4	hSpCas9	negative selection	5330720
165297627	165297649	4	+	27760321	HT29	viability after 10 days	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	0.8071485933247444	[206,161]	[324,370,509]	9	hSpCas9	negative selection	5330721
165297660	165297682	4	+	27760321	HT29	viability after 10 days	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.156800977996971	[588,459]	[598,745,842]	2	hSpCas9	negative selection	5330722
165297696	165297718	4	-	27760321	HT29	viability after 10 days	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.5743532677992271	[146,114]	[52,143,132]	-6	hSpCas9	negative selection	5330723
165263281	165263303	4	+	27760321	MOLM13	viability	GTCAACTGCTTAGGAATCCGGG	KLHL2	ENSG00000109466	-0.6803222345517181	[470,440]	[30,270]	-4	hSpCas9	negative selection	5414182
165297611	165297633	4	+	27760321	MOLM13	viability	ATTTGAAGCAGTAATAGCATGG	KLHL2	ENSG00000109466	-5.054394995531112	[55,60]	[0,0]	-9	hSpCas9	negative selection	5414183
165297627	165297649	4	+	27760321	MOLM13	viability	GCATGGGTGAACCATGACAAGG	KLHL2	ENSG00000109466	1.0018353787073806	[278,206]	[236,301]	7	hSpCas9	negative selection	5414184
165297660	165297682	4	+	27760321	MOLM13	viability	GAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	-0.21601446735289795	[558,588]	[322,243]	-1	hSpCas9	negative selection	5414185
165297696	165297718	4	-	27760321	MOLM13	viability	AATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.07760265004503486	[168,146]	[120,52]	0	hSpCas9	negative selection	5414186
165207622	165207645	4	-	27661255	K562	viability	GGCGGCGGCGACGGGACCGGCGG	KLHL2	ENSG00000109466	0.028966702956785273	[287,239]	[237,196]	1	dCas9-KRAB	negative selection	5488918
165207640	165207663	4	-	27661255	K562	viability	GCGCTCGCCCGAGTGCGGGGCGG	KLHL2	ENSG00000109466	-0.034545327631663625	[312,377]	[240,291]	-1	dCas9-KRAB	negative selection	5488919
165207668	165207691	4	-	27661255	K562	viability	GGCGCGCTCCGTCTACTGCGCGG	KLHL2	ENSG00000109466	0.2307859500521665	[276,423]	[358,297]	7	dCas9-KRAB	negative selection	5488920
165208107	165208130	4	-	27661255	K562	viability	GACCCTTCCCCAGAAATCCTGGG	KLHL2	ENSG00000109466	-0.02911574184198884	[373,438]	[373,268]	-1	dCas9-KRAB	negative selection	5488921
165210133	165210156	4	+	27260156	BXPC3	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.05378775715698625	[1461]	[1424,1342,1634,1495]	-1	hSpCas9	negative selection	5551282
165228816	165228839	4	+	27260156	BXPC3	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.12830957210033378	[1057]	[956,941,1180,968]	-3	hSpCas9	negative selection	5551283
165210166	165210189	4	-	27260156	BXPC3	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.19836777118652948	[179]	[228,178,275,174]	4	hSpCas9	negative selection	5551284
165294447	165294470	4	+	27260156	BXPC3	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.48533799935783906	[374]	[422,519,637,638]	8	hSpCas9	negative selection	5615538
165219925	165219948	4	+	27260156	BXPC3	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.09840767104041537	[282]	[280,296,273,245]	-2	hSpCas9	negative selection	5615539
165294385	165294408	4	+	27260156	BXPC3	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.1505807473129017	[422]	[383,251,407,579]	-3	hSpCas9	negative selection	5615540
165210133	165210156	4	+	27260156	A673	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.2096208978507983	[1461]	[1804,1467,1379,1447]	-5	hSpCas9	negative selection	5672533
165228816	165228839	4	+	27260156	A673	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.3116503545209076	[1057]	[1101,1049,1019,922]	-6	hSpCas9	negative selection	5672534
165210166	165210189	4	-	27260156	A673	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.047757395706635064	[179]	[259,190,168,281]	1	hSpCas9	negative selection	5672535
165294447	165294470	4	+	27260156	A673	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.6289839862281696	[374]	[789,668,654,680]	9	hSpCas9	negative selection	5736789
165219925	165219948	4	+	27260156	A673	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.03295998769269548	[282]	[503,268,268,369]	0	hSpCas9	negative selection	5736790
165294385	165294408	4	+	27260156	A673	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.0534162964399891	[422]	[479,554,464,605]	1	hSpCas9	negative selection	5736791
165210133	165210156	4	+	27260156	A375	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.11276786742458178	[1461]	[1853,1761,1446,1307]	-2	hSpCas9	negative selection	5793784
165228816	165228839	4	+	27260156	A375	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.7400635356260394	[1057]	[635,689,819,795]	-7	hSpCas9	negative selection	5793785
165210166	165210189	4	-	27260156	A375	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.30857685619292163	[179]	[323,249,144,313]	4	hSpCas9	negative selection	5793786
165294447	165294470	4	+	27260156	A375	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.900105689621682	[374]	[771,892,899,722]	9	hSpCas9	negative selection	5858040
165219925	165219948	4	+	27260156	A375	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.13172995189964054	[282]	[270,372,349,229]	-2	hSpCas9	negative selection	5858041
165294385	165294408	4	+	27260156	A375	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.22459683652976725	[422]	[592,563,393,734]	3	hSpCas9	negative selection	5858042
165210133	165210156	4	+	27260156	COLO741	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.13196380499942317	[1461]	[1928,1858,1366]	-3	hSpCas9	negative selection	5915035
165228816	165228839	4	+	27260156	COLO741	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.19246444746695868	[1057]	[1472,1188,927]	-4	hSpCas9	negative selection	5915036
165210166	165210189	4	-	27260156	COLO741	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.15543378227904836	[179]	[222,311,231]	3	hSpCas9	negative selection	5915037
165294447	165294470	4	+	27260156	COLO741	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.3744929999484846	[374]	[607,492,749]	7	hSpCas9	negative selection	5979291
165219925	165219948	4	+	27260156	COLO741	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.43670855176082324	[282]	[315,278,213]	-7	hSpCas9	negative selection	5979292
165294385	165294408	4	+	27260156	COLO741	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.14523281456822393	[422]	[592,535,354]	-3	hSpCas9	negative selection	5979293
165210133	165210156	4	+	27260156	CAL120	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	0.035856954708129773	[1461]	[1545,2221,1779]	0	hSpCas9	negative selection	6036286
165228816	165228839	4	+	27260156	CAL120	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.5199866745564293	[1057]	[1075,906,796]	-6	hSpCas9	negative selection	6036287
165210166	165210189	4	-	27260156	CAL120	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.2683949339207081	[179]	[394,269,164]	4	hSpCas9	negative selection	6036288
165294447	165294470	4	+	27260156	CAL120	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.49090378064591533	[374]	[842,481,669]	7	hSpCas9	negative selection	6100542
165219925	165219948	4	+	27260156	CAL120	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.8514125937512615	[282]	[292,1238,327]	9	hSpCas9	negative selection	6100543
165294385	165294408	4	+	27260156	CAL120	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.5402116057335021	[422]	[536,698,1020]	7	hSpCas9	negative selection	6100544
165210133	165210156	4	+	27260156	CADOES1	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.25035269160025253	[1461]	[1273,1075,1079,1141]	-4	hSpCas9	negative selection	6157537
165228816	165228839	4	+	27260156	CADOES1	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.570995900457588	[1057]	[794,679,594,575]	-7	hSpCas9	negative selection	6157538
165210166	165210189	4	-	27260156	CADOES1	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.06898424078534271	[179]	[112,245,111,167]	-1	hSpCas9	negative selection	6157539
165294447	165294470	4	+	27260156	CADOES1	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7736263187603898	[374]	[530,604,605,644]	9	hSpCas9	negative selection	6221793
165219925	165219948	4	+	27260156	CADOES1	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.1735430866590414	[282]	[133,281,254,263]	-3	hSpCas9	negative selection	6221794
165294385	165294408	4	+	27260156	CADOES1	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.12220010105113274	[422]	[284,369,328,465]	-2	hSpCas9	negative selection	6221795
165210133	165210156	4	+	27260156	EWS502	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.061633651527699174	[1461]	[1500,1514,1522,1379]	-1	hSpCas9	negative selection	6278788
165228816	165228839	4	+	27260156	EWS502	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.6922553930339664	[1057]	[696,644,570,870]	-8	hSpCas9	negative selection	6278789
165210166	165210189	4	-	27260156	EWS502	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.0694376652335611	[179]	[215,181,146,175]	-1	hSpCas9	negative selection	6278790
165294447	165294470	4	+	27260156	EWS502	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.9053879910544865	[374]	[825,564,893,682]	9	hSpCas9	negative selection	6343044
165219925	165219948	4	+	27260156	EWS502	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.09322892447983822	[282]	[285,281,500,208]	1	hSpCas9	negative selection	6343045
165294385	165294408	4	+	27260156	EWS502	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.21229745925538027	[422]	[283,435,525,305]	-4	hSpCas9	negative selection	6343046
165210133	165210156	4	+	27260156	EW8	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.13537671945071206	[1461]	[1245,1142,1054,890]	-3	hSpCas9	negative selection	6400039
165228816	165228839	4	+	27260156	EW8	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.29690056906848716	[1057]	[793,669,681,656]	-5	hSpCas9	negative selection	6400040
165210166	165210189	4	-	27260156	EW8	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.12940678465433875	[179]	[217,111,87,131]	-2	hSpCas9	negative selection	6400041
165294447	165294470	4	+	27260156	EW8	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.625421388514395	[374]	[734,367,391,420]	9	hSpCas9	negative selection	6464295
165219925	165219948	4	+	27260156	EW8	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.07818634972347227	[282]	[331,170,120,272]	-1	hSpCas9	negative selection	6464296
165294385	165294408	4	+	27260156	EW8	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.357518742014027	[422]	[292,254,262,261]	-6	hSpCas9	negative selection	6464297
165210133	165210156	4	+	27260156	CORL105	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.17270641673012999	[1461]	[1725,1372,1496,1483]	-3	hSpCas9	negative selection	6521290
165228816	165228839	4	+	27260156	CORL105	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.22302095805290767	[1057]	[1060,1007,1203,994]	-4	hSpCas9	negative selection	6521291
165210166	165210189	4	-	27260156	CORL105	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.3236023168904436	[179]	[287,175,400,213]	6	hSpCas9	negative selection	6521292
165294447	165294470	4	+	27260156	CORL105	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.6162207098557448	[374]	[787,641,682,584]	9	hSpCas9	negative selection	6585546
165219925	165219948	4	+	27260156	CORL105	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.0774884307987268	[282]	[241,372,281,349]	-1	hSpCas9	negative selection	6585547
165294385	165294408	4	+	27260156	CORL105	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.2123742370991437	[422]	[419,405,373,500]	-4	hSpCas9	negative selection	6585548
165210133	165210156	4	+	27260156	HS294T	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.014108721218274	[1461]	[438,928,379,473]	0	hSpCas9	negative selection	6642541
165228816	165228839	4	+	27260156	HS294T	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.29549959159405037	[1057]	[219,394,307,434]	-4	hSpCas9	negative selection	6642542
165210166	165210189	4	-	27260156	HS294T	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.46573854119868563	[179]	[39,26,66,72]	-6	hSpCas9	negative selection	6642543
165294447	165294470	4	+	27260156	HS294T	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7141203902030522	[374]	[226,253,182,296]	8	hSpCas9	negative selection	6706797
165219925	165219948	4	+	27260156	HS294T	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.5136236775386661	[282]	[83,37,102,82]	-6	hSpCas9	negative selection	6706798
165294385	165294408	4	+	27260156	HS294T	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.10842263357775493	[422]	[320,79,100,194]	1	hSpCas9	negative selection	6706799
165210133	165210156	4	+	27260156	HCC44	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.09982874469549974	[1461]	[1839,1092,1808,1553]	-2	hSpCas9	negative selection	6763792
165228816	165228839	4	+	27260156	HCC44	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.367836117383349	[1057]	[1028,696,1105,941]	-5	hSpCas9	negative selection	6763793
165210166	165210189	4	-	27260156	HCC44	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.07515441956408275	[179]	[309,106,209,170]	-1	hSpCas9	negative selection	6763794
165294447	165294470	4	+	27260156	HCC44	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.6783820101511016	[374]	[753,609,588,754]	9	hSpCas9	negative selection	6828048
165219925	165219948	4	+	27260156	HCC44	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.35205431264439146	[282]	[301,162,202,338]	-5	hSpCas9	negative selection	6828049
165294385	165294408	4	+	27260156	HCC44	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.14611356122050817	[422]	[689,522,476,432]	2	hSpCas9	negative selection	6828050
165210133	165210156	4	+	27260156	G402	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.4179143271040262	[1461]	[1250,1214,1625,1229]	-5	hSpCas9	negative selection	6885043
165228816	165228839	4	+	27260156	G402	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-1.0071979123394381	[1057]	[514,601,767,659]	-8	hSpCas9	negative selection	6885044
165210166	165210189	4	-	27260156	G402	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.3937345598679678	[179]	[84,323,124,132]	-5	hSpCas9	negative selection	6885045
165294447	165294470	4	+	27260156	G402	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	1.0579500188910744	[374]	[901,1000,852,1041]	9	hSpCas9	negative selection	6949299
165219925	165219948	4	+	27260156	G402	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.11991161235871606	[282]	[264,183,531,485]	1	hSpCas9	negative selection	6949300
165294385	165294408	4	+	27260156	G402	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.013151429633185913	[422]	[453,530,536,548]	0	hSpCas9	negative selection	6949301
165210133	165210156	4	+	27260156	L33	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.329416679141433	[1461]	[1155,471,855,986]	-7	hSpCas9	negative selection	7006294
165228816	165228839	4	+	27260156	L33	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.1252103254629977	[1057]	[984,427,587,914]	-3	hSpCas9	negative selection	7006295
165210166	165210189	4	-	27260156	L33	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.008369684024361224	[179]	[169,101,79,177]	0	hSpCas9	negative selection	7006296
165294447	165294470	4	+	27260156	L33	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.5716491393915375	[374]	[482,237,333,634]	9	hSpCas9	negative selection	7070550
165219925	165219948	4	+	27260156	L33	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.15910607110028507	[282]	[223,78,207,266]	-4	hSpCas9	negative selection	7070551
165294385	165294408	4	+	27260156	L33	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.375574033745282	[422]	[272,132,236,330]	-7	hSpCas9	negative selection	7070552
165210133	165210156	4	+	27260156	K562	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.08340808810502032	[1461]	[1365,1052,1237,1236]	-1	hSpCas9	negative selection	7127545
165228816	165228839	4	+	27260156	K562	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.24269089500019148	[1057]	[1464,429,587,730]	-3	hSpCas9	negative selection	7127546
165210166	165210189	4	-	27260156	K562	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.2011480413244986	[179]	[175,200,172,183]	2	hSpCas9	negative selection	7127547
165294447	165294470	4	+	27260156	K562	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7127829303908706	[374]	[659,544,440,542]	8	hSpCas9	negative selection	7191801
165219925	165219948	4	+	27260156	K562	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.04548295417473569	[282]	[313,377,245,67]	0	hSpCas9	negative selection	7191802
165294385	165294408	4	+	27260156	K562	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.1457355408119183	[422]	[703,295,546,159]	1	hSpCas9	negative selection	7191803
165210133	165210156	4	+	27260156	HT29	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.066477476041098	[1461]	[1925,1692,1552,1629]	-1	hSpCas9	negative selection	7248796
165228816	165228839	4	+	27260156	HT29	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	0.0049263554617653416	[1057]	[1513,1009,1494,1144]	0	hSpCas9	negative selection	7248797
165210166	165210189	4	-	27260156	HT29	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.12287987410029566	[179]	[229,258,247,217]	2	hSpCas9	negative selection	7248798
165294447	165294470	4	+	27260156	HT29	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.8310239014884252	[374]	[820,840,927,668]	9	hSpCas9	negative selection	7313052
165219925	165219948	4	+	27260156	HT29	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.1045808194404878	[282]	[337,384,308,259]	-2	hSpCas9	negative selection	7313053
165294385	165294408	4	+	27260156	HT29	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.09422052447987042	[422]	[640,418,494,386]	-2	hSpCas9	negative selection	7313054
165210133	165210156	4	+	27260156	MHHES1	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.3538802188551107	[1461]	[1623,1644,1098,918]	-6	hSpCas9	negative selection	7370047
165228816	165228839	4	+	27260156	MHHES1	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.2854461670955277	[1057]	[1128,1106,1004,735]	-5	hSpCas9	negative selection	7370048
165210166	165210189	4	-	27260156	MHHES1	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.4878957129626267	[179]	[92,194,86,187]	-7	hSpCas9	negative selection	7370049
165294447	165294470	4	+	27260156	MHHES1	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7790611614298559	[374]	[976,778,636,562]	9	hSpCas9	negative selection	7434303
165219925	165219948	4	+	27260156	MHHES1	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.19899329841214353	[282]	[300,641,241,303]	3	hSpCas9	negative selection	7434304
165294385	165294408	4	+	27260156	MHHES1	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.16183356039581068	[422]	[470,396,240,554]	-3	hSpCas9	negative selection	7434305
165210133	165210156	4	+	27260156	MEWO	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.2803130472270885	[1461]	[1341,985,1092]	-6	hSpCas9	negative selection	7491298
165228816	165228839	4	+	27260156	MEWO	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.32571703075790204	[1057]	[957,740,702]	-6	hSpCas9	negative selection	7491299
165210166	165210189	4	-	27260156	MEWO	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.2712591722808204	[179]	[280,147,195]	6	hSpCas9	negative selection	7491300
165294447	165294470	4	+	27260156	MEWO	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.2597899933683772	[374]	[552,385,346]	5	hSpCas9	negative selection	7555554
165219925	165219948	4	+	27260156	MEWO	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.0761452234888853	[282]	[279,248,229]	-2	hSpCas9	negative selection	7555555
165294385	165294408	4	+	27260156	MEWO	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.13052878176418883	[422]	[522,422,370]	3	hSpCas9	negative selection	7555556
165210133	165210156	4	+	27260156	LNCAPCLONEFGC	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.18637994192810248	[1461]	[1060,1208,963,1389]	-3	hSpCas9	negative selection	7612549
165228816	165228839	4	+	27260156	LNCAPCLONEFGC	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.4251272440873668	[1057]	[712,804,695,631]	-6	hSpCas9	negative selection	7612550
165210166	165210189	4	-	27260156	LNCAPCLONEFGC	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.19178506535871165	[179]	[89,219,163,95]	-3	hSpCas9	negative selection	7612551
165294447	165294470	4	+	27260156	LNCAPCLONEFGC	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7419919521476774	[374]	[723,491,620,444]	9	hSpCas9	negative selection	7676805
165219925	165219948	4	+	27260156	LNCAPCLONEFGC	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.016654730756429648	[282]	[307,245,253,204]	0	hSpCas9	negative selection	7676806
165294385	165294408	4	+	27260156	LNCAPCLONEFGC	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.29187745571782076	[422]	[472,478,513,415]	4	hSpCas9	negative selection	7676807
165210133	165210156	4	+	27260156	PANC0327	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	0.0322834878017888	[1461]	[1428,1108,1143,1665]	0	hSpCas9	negative selection	7733800
165228816	165228839	4	+	27260156	PANC0327	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.3466852719700303	[1057]	[742,617,769,840]	-5	hSpCas9	negative selection	7733801
165210166	165210189	4	-	27260156	PANC0327	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.47003796397110853	[179]	[177,177,290,240]	7	hSpCas9	negative selection	7733802
165294447	165294470	4	+	27260156	PANC0327	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7029350900301499	[374]	[519,431,479,748]	8	hSpCas9	negative selection	7798056
165219925	165219948	4	+	27260156	PANC0327	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.6912933869776655	[282]	[240,91,189,114]	-7	hSpCas9	negative selection	7798057
165294385	165294408	4	+	27260156	PANC0327	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.13125524353098963	[422]	[267,172,413,532]	-2	hSpCas9	negative selection	7798058
165210133	165210156	4	+	27260156	NCIH2009	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.22669863365101106	[1461]	[1774,1673,1791]	-3	hSpCas9	negative selection	7855051
165228816	165228839	4	+	27260156	NCIH2009	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.5300410382614832	[1057]	[1363,1002,769]	-6	hSpCas9	negative selection	7855052
165210166	165210189	4	-	27260156	NCIH2009	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.10496739600720195	[179]	[318,244,256]	1	hSpCas9	negative selection	7855053
165294447	165294470	4	+	27260156	NCIH2009	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	1.1740806126892358	[374]	[1421,748,1428]	9	hSpCas9	negative selection	7919307
165219925	165219948	4	+	27260156	NCIH2009	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.1754798918293058	[282]	[262,433,333]	-2	hSpCas9	negative selection	7919308
165294385	165294408	4	+	27260156	NCIH2009	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.0032833011731505657	[422]	[546,728,480]	0	hSpCas9	negative selection	7919309
165210133	165210156	4	+	27260156	NCIH1373	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.26087053901308455	[1461]	[1822,724,1539,399]	-3	hSpCas9	negative selection	7976302
165228816	165228839	4	+	27260156	NCIH1373	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.8004311421123171	[1057]	[677,701,561,205]	-7	hSpCas9	negative selection	7976303
165210166	165210189	4	-	27260156	NCIH1373	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.7265844490907187	[179]	[650,332,181,55]	7	hSpCas9	negative selection	7976304
165294447	165294470	4	+	27260156	NCIH1373	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	1.1176027152427142	[374]	[848,791,755,334]	9	hSpCas9	negative selection	8040558
165219925	165219948	4	+	27260156	NCIH1373	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.07253034403466618	[282]	[283,374,203,122]	0	hSpCas9	negative selection	8040559
165294385	165294408	4	+	27260156	NCIH1373	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.08774357376230776	[422]	[779,247,320,134]	-1	hSpCas9	negative selection	8040560
165210133	165210156	4	+	27260156	PATU8902	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	0.31636796467934825	[1461]	[2702,2852,1908,2855]	3	hSpCas9	negative selection	8097553
165228816	165228839	4	+	27260156	PATU8902	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.6095608495074774	[1057]	[908,1027,1035,850]	-5	hSpCas9	negative selection	8097554
165210166	165210189	4	-	27260156	PATU8902	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.21403591142457556	[179]	[106,98,309,337]	-2	hSpCas9	negative selection	8097555
165294447	165294470	4	+	27260156	PATU8902	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.9980117998841461	[374]	[597,1709,733,1232]	9	hSpCas9	negative selection	8161809
165219925	165219948	4	+	27260156	PATU8902	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.04909506099941119	[282]	[348,507,325,348]	0	hSpCas9	negative selection	8161810
165294385	165294408	4	+	27260156	PATU8902	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.25316913707139166	[422]	[870,900,370,749]	2	hSpCas9	negative selection	8161811
165210133	165210156	4	+	27260156	PANC1	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.04965455164275623	[1461]	[1238,1538,909,1208]	-1	hSpCas9	negative selection	8218804
165228816	165228839	4	+	27260156	PANC1	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.5171757239060957	[1057]	[667,779,725,420]	-7	hSpCas9	negative selection	8218805
165210166	165210189	4	-	27260156	PANC1	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.9850027822232755	[179]	[265,438,370,190]	9	hSpCas9	negative selection	8218806
165294447	165294470	4	+	27260156	PANC1	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.8072848197481561	[374]	[453,780,482,571]	9	hSpCas9	negative selection	8283060
165219925	165219948	4	+	27260156	PANC1	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.08749397283359728	[282]	[128,232,303,245]	-1	hSpCas9	negative selection	8283061
165294385	165294408	4	+	27260156	PANC1	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	0.07450264582609382	[422]	[347,392,436,353]	1	hSpCas9	negative selection	8283062
165210133	165210156	4	+	27260156	PANC0813	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.2818199701727384	[1461]	[1292,1210,1368,1744]	-4	hSpCas9	negative selection	8340055
165228816	165228839	4	+	27260156	PANC0813	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.6189690015311857	[1057]	[705,888,1010,630]	-7	hSpCas9	negative selection	8340056
165210166	165210189	4	-	27260156	PANC0813	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.2137098791246792	[179]	[146,274,208,334]	3	hSpCas9	negative selection	8340057
165294447	165294470	4	+	27260156	PANC0813	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.2913789804769074	[374]	[564,459,591,540]	5	hSpCas9	negative selection	8404311
165219925	165219948	4	+	27260156	PANC0813	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.008979199979514352	[282]	[222,344,586,181]	0	hSpCas9	negative selection	8404312
165294385	165294408	4	+	27260156	PANC0813	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.2079974806404937	[422]	[498,420,460,349]	-3	hSpCas9	negative selection	8404313
165210133	165210156	4	+	27260156	RDES	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.16753487139983947	[1461]	[1294,1548,1421,1747]	-3	hSpCas9	negative selection	8461306
165228816	165228839	4	+	27260156	RDES	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.4386645032889884	[1057]	[662,945,1034,984]	-6	hSpCas9	negative selection	8461307
165210166	165210189	4	-	27260156	RDES	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.06947319787257378	[179]	[211,177,130,267]	-1	hSpCas9	negative selection	8461308
165294447	165294470	4	+	27260156	RDES	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7593896654801056	[374]	[585,634,893,847]	9	hSpCas9	negative selection	8525562
165219925	165219948	4	+	27260156	RDES	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.12629488425687974	[282]	[217,200,363,454]	-2	hSpCas9	negative selection	8525563
165294385	165294408	4	+	27260156	RDES	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.054163065555308365	[422]	[424,479,573,377]	-1	hSpCas9	negative selection	8525564
165210133	165210156	4	+	27260156	PC3	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.23978860590914652	[1461]	[789,1447,1825,1156]	-5	hSpCas9	negative selection	8582557
165228816	165228839	4	+	27260156	PC3	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.18513966053661046	[1057]	[525,957,1602,979]	-4	hSpCas9	negative selection	8582558
165210166	165210189	4	-	27260156	PC3	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.15837431092186516	[179]	[130,119,268,160]	-4	hSpCas9	negative selection	8582559
165294447	165294470	4	+	27260156	PC3	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.5144620527190908	[374]	[305,483,1016,573]	9	hSpCas9	negative selection	8646813
165219925	165219948	4	+	27260156	PC3	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.06164451996929898	[282]	[211,207,600,284]	1	hSpCas9	negative selection	8646814
165294385	165294408	4	+	27260156	PC3	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.40046350715437673	[422]	[224,240,523,381]	-7	hSpCas9	negative selection	8646815
165210133	165210156	4	+	27260156	PATU8988T	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.336913800769467	[1461]	[1210,1127,1087,1041]	-5	hSpCas9	negative selection	8703808
165228816	165228839	4	+	27260156	PATU8988T	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.23241920314160258	[1057]	[874,869,843,893]	-4	hSpCas9	negative selection	8703809
165210166	165210189	4	-	27260156	PATU8988T	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.7536118107474171	[179]	[139,333,350,355]	9	hSpCas9	negative selection	8703810
165294447	165294470	4	+	27260156	PATU8988T	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7144208339412541	[374]	[488,734,627,533]	9	hSpCas9	negative selection	8768064
165219925	165219948	4	+	27260156	PATU8988T	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.3787329421052924	[282]	[218,286,186,150]	-6	hSpCas9	negative selection	8768065
165294385	165294408	4	+	27260156	PATU8988T	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.4211873235004856	[422]	[323,245,299,348]	-6	hSpCas9	negative selection	8768066
165210133	165210156	4	+	27260156	T47D	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.13753492028106185	[1461]	[1602,1712,1425,1434]	-3	hSpCas9	negative selection	8825059
165228816	165228839	4	+	27260156	T47D	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.26969746605058864	[1057]	[1030,1103,1020,922]	-5	hSpCas9	negative selection	8825060
165210166	165210189	4	-	27260156	T47D	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	0.011088862020012913	[179]	[184,225,213,218]	0	hSpCas9	negative selection	8825061
165294447	165294470	4	+	27260156	T47D	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7263954010411631	[374]	[710,617,766,805]	9	hSpCas9	negative selection	8889315
165219925	165219948	4	+	27260156	T47D	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.03919600839782911	[282]	[317,368,248,344]	-1	hSpCas9	negative selection	8889316
165294385	165294408	4	+	27260156	T47D	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.07412756064613163	[422]	[432,433,436,574]	-2	hSpCas9	negative selection	8889317
165210133	165210156	4	+	27260156	SU8686	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.1521992932431968	[1461]	[1346,1084,1125,1738]	-3	hSpCas9	negative selection	8946310
165228816	165228839	4	+	27260156	SU8686	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.10448099641289788	[1057]	[842,966,911,1228]	-2	hSpCas9	negative selection	8946311
165210166	165210189	4	-	27260156	SU8686	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.12777359800419896	[179]	[123,151,180,208]	-2	hSpCas9	negative selection	8946312
165294447	165294470	4	+	27260156	SU8686	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.8118148175069726	[374]	[565,637,636,799]	9	hSpCas9	negative selection	9010566
165219925	165219948	4	+	27260156	SU8686	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.38499225526533143	[282]	[269,138,250,199]	-6	hSpCas9	negative selection	9010567
165294385	165294408	4	+	27260156	SU8686	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.15188688058352376	[422]	[281,318,442,503]	-3	hSpCas9	negative selection	9010568
165210133	165210156	4	+	27260156	SKES1	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.11993427037460491	[1461]	[1537,1205,1408,1224]	-3	hSpCas9	negative selection	9067561
165228816	165228839	4	+	27260156	SKES1	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.31951158066945706	[1057]	[788,857,862,855]	-6	hSpCas9	negative selection	9067562
165210166	165210189	4	-	27260156	SKES1	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.3047416047742273	[179]	[184,177,110,118]	-6	hSpCas9	negative selection	9067563
165294447	165294470	4	+	27260156	SKES1	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.452947290696849	[374]	[454,447,581,537]	8	hSpCas9	negative selection	9131817
165219925	165219948	4	+	27260156	SKES1	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.12392328350893123	[282]	[269,253,266,244]	-3	hSpCas9	negative selection	9131818
165294385	165294408	4	+	27260156	SKES1	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.32428236967229096	[422]	[322,351,369,302]	-6	hSpCas9	negative selection	9131819
165210133	165210156	4	+	27260156	TOV112D	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.2523706421357985	[1461]	[1175,1859,1097,939]	-5	hSpCas9	negative selection	9188812
165228816	165228839	4	+	27260156	TOV112D	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.44154789112831994	[1057]	[1069,903,579,624]	-7	hSpCas9	negative selection	9188813
165210166	165210189	4	-	27260156	TOV112D	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.10515700735705336	[179]	[216,261,103,115]	-2	hSpCas9	negative selection	9188814
165294447	165294470	4	+	27260156	TOV112D	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.4512961089605787	[374]	[759,455,408,436]	8	hSpCas9	negative selection	9253068
165219925	165219948	4	+	27260156	TOV112D	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	0.3042629297562219	[282]	[538,273,284,299]	6	hSpCas9	negative selection	9253069
165294385	165294408	4	+	27260156	TOV112D	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.20805940272517512	[422]	[186,367,471,422]	-4	hSpCas9	negative selection	9253070
165210133	165210156	4	+	27260156	TC71	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.1866235355461674	[1461]	[1368,1185,1338,1630]	-5	hSpCas9	negative selection	9310063
165228816	165228839	4	+	27260156	TC71	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.09099845355967218	[1057]	[1253,842,991,1174]	-2	hSpCas9	negative selection	9310064
165210166	165210189	4	-	27260156	TC71	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.11600582245316216	[179]	[217,197,130,164]	-3	hSpCas9	negative selection	9310065
165294447	165294470	4	+	27260156	TC71	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.5944496416894416	[374]	[656,590,579,598]	9	hSpCas9	negative selection	9374319
165219925	165219948	4	+	27260156	TC71	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.4123913432525862	[282]	[240,257,193,218]	-8	hSpCas9	negative selection	9374320
165294385	165294408	4	+	27260156	TC71	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.06072311425946278	[422]	[440,370,469,456]	-1	hSpCas9	negative selection	9374321
165210133	165210156	4	+	27260156	TC32	viability	AAAGTGCCTTATGGTATGGTTGG	KLHL2	ENSG00000109466	-0.503224511245733	[1461]	[850,656,1293,1223]	-7	hSpCas9	negative selection	9431314
165228816	165228839	4	+	27260156	TC32	viability	GCTGTGCGATGTCACAATTGTGG	KLHL2	ENSG00000109466	-0.543986920159844	[1057]	[616,510,792,868]	-8	hSpCas9	negative selection	9431315
165210166	165210189	4	-	27260156	TC32	viability	ACACTTACACAAAGAGAATCTGG	KLHL2	ENSG00000109466	-0.4052114014739727	[179]	[135,54,218,136]	-6	hSpCas9	negative selection	9431316
165294447	165294470	4	+	27260156	TC32	viability	TACCATTTCTTCAGAAGAGAAGG	KLHL2	ENSG00000109466	0.7316880043382079	[374]	[426,459,910,635]	9	hSpCas9	negative selection	9495570
165219925	165219948	4	+	27260156	TC32	viability	TATGTACAGATGCACAAAGCAGG	KLHL2	ENSG00000109466	-0.12914825109413686	[282]	[226,153,312,316]	-2	hSpCas9	negative selection	9495571
165294385	165294408	4	+	27260156	TC32	viability	AGTGAAGAATTTCTCAATCTTGG	KLHL2	ENSG00000109466	-0.16018997867367454	[422]	[342,279,393,424]	-3	hSpCas9	negative selection	9495572
165207858	165207881	4	+	27869803	HPAFII	viability after 27 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.5363766134191317	[492]	[256,474,NaN]	4	hSpCas9	negative selection	9587433
165299497	165299520	4	+	27869803	HPAFII	viability after 27 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.8259694236283981	[392]	[344,383,NaN]	6	hSpCas9	negative selection	9587434
165310658	165310681	4	+	27869803	HPAFII	viability after 27 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	-0.1994306955565892	[410]	[221,159,NaN]	-1	hSpCas9	negative selection	9587435
165311515	165311538	4	+	27869803	HPAFII	viability after 27 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.8402111134898999	[262]	[192,292,NaN]	6	hSpCas9	negative selection	9587436
165313339	165313362	4	+	27869803	HPAFII	viability after 27 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.5549043001464842	[239]	[264,118,NaN]	4	hSpCas9	negative selection	9587437
165314111	165314134	4	+	27869803	HPAFII	viability after 27 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.3488272118842366	[410]	[224,316,NaN]	3	hSpCas9	negative selection	9587438
165207858	165207881	4	+	27869803	HPAFII	viability after 15 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.4000659678847833	[492]	[655,725,NaN]	4	hSpCas9	negative selection	9669882
165299497	165299520	4	+	27869803	HPAFII	viability after 15 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.8460294419218961	[392]	[1225,468,NaN]	8	hSpCas9	negative selection	9669883
165310658	165310681	4	+	27869803	HPAFII	viability after 15 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	-0.0781713431813279	[410]	[595,307,NaN]	-1	hSpCas9	negative selection	9669884
165311515	165311538	4	+	27869803	HPAFII	viability after 15 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.9609922517492007	[262]	[667,476,NaN]	9	hSpCas9	negative selection	9669885
165313339	165313362	4	+	27869803	HPAFII	viability after 15 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.11592166764144057	[239]	[445,175,NaN]	1	hSpCas9	negative selection	9669886
165314111	165314134	4	+	27869803	HPAFII	viability after 15 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.3569416152596818	[410]	[635,521,NaN]	4	hSpCas9	negative selection	9669887
165207858	165207881	4	+	27869803	ASPC1	viability after 36 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	-0.22764095943776919	[1041]	[356,511,114]	-2	hSpCas9	negative selection	9752331
165299497	165299520	4	+	27869803	ASPC1	viability after 36 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.5232429845175769	[1164]	[350,605,724]	5	hSpCas9	negative selection	9752332
165310658	165310681	4	+	27869803	ASPC1	viability after 36 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	-0.03618739519714803	[885]	[350,415,172]	0	hSpCas9	negative selection	9752333
165311515	165311538	4	+	27869803	ASPC1	viability after 36 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.00672854259260644	[716]	[473,177,150]	0	hSpCas9	negative selection	9752334
165313339	165313362	4	+	27869803	ASPC1	viability after 36 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.14288185711488274	[630]	[325,127,273]	1	hSpCas9	negative selection	9752335
165314111	165314134	4	+	27869803	ASPC1	viability after 36 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.9364267671580287	[844]	[452,271,868]	8	hSpCas9	negative selection	9752336
165207858	165207881	4	+	27869803	PATU8988S	viability after 35 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.6590025555842945	[812]	[524,508,NaN]	7	hSpCas9	negative selection	9834780
165299497	165299520	4	+	27869803	PATU8988S	viability after 35 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.32419160172855344	[830]	[424,412,NaN]	3	hSpCas9	negative selection	9834781
165310658	165310681	4	+	27869803	PATU8988S	viability after 35 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	1.2398724658023141	[660]	[517,739,NaN]	9	hSpCas9	negative selection	9834782
165311515	165311538	4	+	27869803	PATU8988S	viability after 35 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.4170308305795435	[579]	[154,194,NaN]	-4	hSpCas9	negative selection	9834783
165313339	165313362	4	+	27869803	PATU8988S	viability after 35 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-1.7860213704625882	[646]	[101,48,NaN]	-8	hSpCas9	negative selection	9834784
165314111	165314134	4	+	27869803	PATU8988S	viability after 35 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.7648404461856417	[602]	[482,341,NaN]	7	hSpCas9	negative selection	9834785
165207858	165207881	4	+	27869803	PATU8988S	viability after 31 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.6691620552032528	[812]	[573,440,NaN]	7	hSpCas9	negative selection	9917229
165299497	165299520	4	+	27869803	PATU8988S	viability after 31 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	-0.0940883233733204	[830]	[287,338,NaN]	-1	hSpCas9	negative selection	9917230
165310658	165310681	4	+	27869803	PATU8988S	viability after 31 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.9203583972836644	[660]	[438,574,NaN]	8	hSpCas9	negative selection	9917231
165311515	165311538	4	+	27869803	PATU8988S	viability after 31 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-0.4913489797735876	[579]	[149,182,NaN]	-5	hSpCas9	negative selection	9917232
165313339	165313362	4	+	27869803	PATU8988S	viability after 31 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	-1.6210198827955924	[646]	[49,126,NaN]	-8	hSpCas9	negative selection	9917233
165314111	165314134	4	+	27869803	PATU8988S	viability after 31 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.7949134694059024	[602]	[421,410,NaN]	8	hSpCas9	negative selection	9917234
165207858	165207881	4	+	27869803	HPAFII	viability after 35 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.8176933592310405	[492]	[128,789,NaN]	5	hSpCas9	negative selection	9999678
165299497	165299520	4	+	27869803	HPAFII	viability after 35 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	0.8747212421279278	[392]	[345,385,NaN]	6	hSpCas9	negative selection	9999679
165310658	165310681	4	+	27869803	HPAFII	viability after 35 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	0.09692207111411577	[410]	[214,230,NaN]	0	hSpCas9	negative selection	9999680
165311515	165311538	4	+	27869803	HPAFII	viability after 35 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.5213147397631424	[262]	[144,242,NaN]	3	hSpCas9	negative selection	9999681
165313339	165313362	4	+	27869803	HPAFII	viability after 35 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.7332965178605504	[239]	[169,237,NaN]	5	hSpCas9	negative selection	9999682
165314111	165314134	4	+	27869803	HPAFII	viability after 35 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	1.0182866106010593	[410]	[364,484,NaN]	7	hSpCas9	negative selection	9999683
165207858	165207881	4	+	27869803	HPAFII	viability after 31 days	AAGCCCGAGAGGAGCCACAATGG	KLHL2	ENSG00000109466	0.5481779913227396	[492]	[260,560,NaN]	4	hSpCas9	negative selection	10082127
165299497	165299520	4	+	27869803	HPAFII	viability after 31 days	CTTGTTACAGAGGGTTGAAGAGG	KLHL2	ENSG00000109466	1.0309178769275835	[392]	[420,482,NaN]	7	hSpCas9	negative selection	10082128
165310658	165310681	4	+	27869803	HPAFII	viability after 31 days	GCGTTGCTAACATGAGAGACCGG	KLHL2	ENSG00000109466	-0.6434462581311555	[410]	[195,94,NaN]	-4	hSpCas9	negative selection	10082129
165311515	165311538	4	+	27869803	HPAFII	viability after 31 days	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	1.0157631252541748	[262]	[218,384,NaN]	7	hSpCas9	negative selection	10082130
165313339	165313362	4	+	27869803	HPAFII	viability after 31 days	GAAATGAGCACCAGGCGGAGTGG	KLHL2	ENSG00000109466	0.46763254702421186	[239]	[191,179,NaN]	3	hSpCas9	negative selection	10082131
165314111	165314134	4	+	27869803	HPAFII	viability after 31 days	CACCACTAACGCATGGAGACAGG	KLHL2	ENSG00000109466	0.25467582995688043	[410]	[178,379,NaN]	1	hSpCas9	negative selection	10082132
165305693	165305716	4	+	28162770	P31FUJ	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.5060177538128997	[310]	[518]	6	hSpCas9	negative selection	10180408
165311515	165311538	4	+	28162770	P31FUJ	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.1107847716027569	[118]	[150]	1	hSpCas9	negative selection	10180409
165313334	165313357	4	+	28162770	P31FUJ	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.7584594585079218	[413]	[822]	8	hSpCas9	negative selection	10180410
165314104	165314127	4	+	28162770	P31FUJ	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.45126844131970206	[149]	[240]	5	hSpCas9	negative selection	10180411
165297659	165297682	4	+	28162770	P31FUJ	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.31814335808034155	[328]	[481]	3	hSpCas9	negative selection	10180412
165297696	165297719	4	-	28162770	P31FUJ	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.3925180339229184	[93]	[144]	4	hSpCas9	negative selection	10180413
165299506	165299529	4	+	28162770	P31FUJ	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.06841538651349627	[173]	[194]	0	hSpCas9	negative selection	10180414
165299613	165299636	4	+	28162770	P31FUJ	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.09178687193605162	[324]	[406]	0	hSpCas9	negative selection	10180415
165299647	165299670	4	-	28162770	P31FUJ	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.39682934564050565	[582]	[901]	4	hSpCas9	negative selection	10180416
165310631	165310654	4	+	28162770	P31FUJ	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.45125672642580494	[510]	[820]	5	hSpCas9	negative selection	10180417
165305693	165305716	4	+	28162770	TF1	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	NaN	[NaN]	[282]	1	hSpCas9	negative selection	10349774
165311515	165311538	4	+	28162770	TF1	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	NaN	[NaN]	[129]	1	hSpCas9	negative selection	10349775
165313334	165313357	4	+	28162770	TF1	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	NaN	[NaN]	[508]	1	hSpCas9	negative selection	10349776
165314104	165314127	4	+	28162770	TF1	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	NaN	[NaN]	[276]	1	hSpCas9	negative selection	10349777
165297659	165297682	4	+	28162770	TF1	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10349778
165297696	165297719	4	-	28162770	TF1	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10349779
165299506	165299529	4	+	28162770	TF1	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10349780
165299613	165299636	4	+	28162770	TF1	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	NaN	[NaN]	[320]	1	hSpCas9	negative selection	10349781
165299647	165299670	4	-	28162770	TF1	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	NaN	[NaN]	[903]	1	hSpCas9	negative selection	10349782
165310631	165310654	4	+	28162770	TF1	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	NaN	[NaN]	[586]	1	hSpCas9	negative selection	10349783
165305693	165305716	4	+	28162770	SKM1	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.3698159092691491	[108]	[248]	3	hSpCas9	negative selection	10519140
165311515	165311538	4	+	28162770	SKM1	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	1.041936752401966	[24]	[90]	8	hSpCas9	negative selection	10519141
165313334	165313357	4	+	28162770	SKM1	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	-0.15953962936633603	[150]	[238]	-1	hSpCas9	negative selection	10519142
165314104	165314127	4	+	28162770	SKM1	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	-0.029443777892481968	[55]	[96]	0	hSpCas9	negative selection	10519143
165297659	165297682	4	+	28162770	SKM1	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.24563701885335765	[124]	[261]	2	hSpCas9	negative selection	10519144
165297696	165297719	4	-	28162770	SKM1	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.1990599175058244	[33]	[68]	2	hSpCas9	negative selection	10519145
165299506	165299529	4	+	28162770	SKM1	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.5548976278791649	[58]	[70]	-4	hSpCas9	negative selection	10519146
165299613	165299636	4	+	28162770	SKM1	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.30162965114637186	[94]	[206]	3	hSpCas9	negative selection	10519147
165299647	165299670	4	-	28162770	SKM1	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.6117549986034274	[133]	[361]	6	hSpCas9	negative selection	10519148
165310631	165310654	4	+	28162770	SKM1	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.005418847089704304	[101]	[180]	0	hSpCas9	negative selection	10519149
165305693	165305716	4	+	28162770	SKM1	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.3698159092691491	[108]	[248]	3	hSpCas9	negative selection	10688506
165311515	165311538	4	+	28162770	SKM1	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	1.041936752401966	[24]	[90]	8	hSpCas9	negative selection	10688507
165313334	165313357	4	+	28162770	SKM1	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	-0.15953962936633603	[150]	[238]	-1	hSpCas9	negative selection	10688508
165314104	165314127	4	+	28162770	SKM1	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	-0.029443777892481968	[55]	[96]	0	hSpCas9	negative selection	10688509
165297659	165297682	4	+	28162770	SKM1	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.24563701885335765	[124]	[261]	2	hSpCas9	negative selection	10688510
165297696	165297719	4	-	28162770	SKM1	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.1990599175058244	[33]	[68]	2	hSpCas9	negative selection	10688511
165299506	165299529	4	+	28162770	SKM1	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.5548976278791649	[58]	[70]	-4	hSpCas9	negative selection	10688512
165299613	165299636	4	+	28162770	SKM1	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.30162965114637186	[94]	[206]	3	hSpCas9	negative selection	10688513
165299647	165299670	4	-	28162770	SKM1	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.6117549986034274	[133]	[361]	6	hSpCas9	negative selection	10688514
165310631	165310654	4	+	28162770	SKM1	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.005418847089704304	[101]	[180]	0	hSpCas9	negative selection	10688515
165305693	165305716	4	+	28162770	PL21	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.2864644143136921	[372]	[197]	2	hSpCas9	negative selection	10857872
165311515	165311538	4	+	28162770	PL21	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.5537765691040207	[71]	[45]	5	hSpCas9	negative selection	10857873
165313334	165313357	4	+	28162770	PL21	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.2777081679850235	[524]	[276]	2	hSpCas9	negative selection	10857874
165314104	165314127	4	+	28162770	PL21	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.20013961448932005	[169]	[84]	1	hSpCas9	negative selection	10857875
165297659	165297682	4	+	28162770	PL21	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.9163466484887288	[335]	[275]	7	hSpCas9	negative selection	10857876
165297696	165297719	4	-	28162770	PL21	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-1.3733272473940066	[124]	[20]	-7	hSpCas9	negative selection	10857877
165299506	165299529	4	+	28162770	PL21	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.7305977230735664	[121]	[31]	-5	hSpCas9	negative selection	10857878
165299613	165299636	4	+	28162770	PL21	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	-0.44292584079540426	[227]	[72]	-3	hSpCas9	negative selection	10857879
165299647	165299670	4	-	28162770	PL21	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	1.1205883153925604	[465]	[440]	8	hSpCas9	negative selection	10857880
165310631	165310654	4	+	28162770	PL21	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	-0.39209088669587544	[397]	[131]	-3	hSpCas9	negative selection	10857881
165305693	165305716	4	+	28162770	P31FUJ	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.5060177538128997	[310]	[518]	6	hSpCas9	negative selection	11027238
165311515	165311538	4	+	28162770	P31FUJ	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.1107847716027569	[118]	[150]	1	hSpCas9	negative selection	11027239
165313334	165313357	4	+	28162770	P31FUJ	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.7584594585079218	[413]	[822]	8	hSpCas9	negative selection	11027240
165314104	165314127	4	+	28162770	P31FUJ	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.45126844131970206	[149]	[240]	5	hSpCas9	negative selection	11027241
165297659	165297682	4	+	28162770	P31FUJ	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.31814335808034155	[328]	[481]	3	hSpCas9	negative selection	11027242
165297696	165297719	4	-	28162770	P31FUJ	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.3925180339229184	[93]	[144]	4	hSpCas9	negative selection	11027243
165299506	165299529	4	+	28162770	P31FUJ	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.06841538651349627	[173]	[194]	0	hSpCas9	negative selection	11027244
165299613	165299636	4	+	28162770	P31FUJ	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.09178687193605162	[324]	[406]	0	hSpCas9	negative selection	11027245
165299647	165299670	4	-	28162770	P31FUJ	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.39682934564050565	[582]	[901]	4	hSpCas9	negative selection	11027246
165310631	165310654	4	+	28162770	P31FUJ	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.45125672642580494	[510]	[820]	5	hSpCas9	negative selection	11027247
165305693	165305716	4	+	28162770	OCIAML5	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.44455043549417783	[183]	[451]	4	hSpCas9	negative selection	11196604
165311515	165311538	4	+	28162770	OCIAML5	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.32302013569409416	[61]	[139]	2	hSpCas9	negative selection	11196605
165313334	165313357	4	+	28162770	OCIAML5	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.2992427524109684	[311]	[692]	2	hSpCas9	negative selection	11196606
165314104	165314127	4	+	28162770	OCIAML5	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.5238003311341689	[83]	[217]	4	hSpCas9	negative selection	11196607
165297659	165297682	4	+	28162770	OCIAML5	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.4048886666375848	[217]	[520]	3	hSpCas9	negative selection	11196608
165297696	165297719	4	-	28162770	OCIAML5	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.03680645072104671	[103]	[182]	0	hSpCas9	negative selection	11196609
165299506	165299529	4	+	28162770	OCIAML5	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-1.5171994202691366	[110]	[69]	-7	hSpCas9	negative selection	11196610
165299613	165299636	4	+	28162770	OCIAML5	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	1.001499616321743	[157]	[570]	8	hSpCas9	negative selection	11196611
165299647	165299670	4	-	28162770	OCIAML5	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.21649771561907438	[451]	[947]	1	hSpCas9	negative selection	11196612
165310631	165310654	4	+	28162770	OCIAML5	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.7150571240194709	[216]	[642]	6	hSpCas9	negative selection	11196613
165305693	165305716	4	+	28162770	EOL1	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	-0.010963501977751644	[699]	[365]	0	hSpCas9	negative selection	11365970
165311515	165311538	4	+	28162770	EOL1	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-1.9367459575978732	[108]	[14]	-8	hSpCas9	negative selection	11365971
165313334	165313357	4	+	28162770	EOL1	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.384723546123072	[880]	[605]	3	hSpCas9	negative selection	11365972
165314104	165314127	4	+	28162770	EOL1	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.9559607242019963	[317]	[324]	8	hSpCas9	negative selection	11365973
165297659	165297682	4	+	28162770	EOL1	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.966503088011913	[609]	[627]	8	hSpCas9	negative selection	11365974
165297696	165297719	4	-	28162770	EOL1	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	1.0262431686398854	[177]	[190]	8	hSpCas9	negative selection	11365975
165299506	165299529	4	+	28162770	EOL1	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	0.1661688708884762	[180]	[106]	1	hSpCas9	negative selection	11365976
165299613	165299636	4	+	28162770	EOL1	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.4224314840293476	[312]	[220]	4	hSpCas9	negative selection	11365977
165299647	165299670	4	-	28162770	EOL1	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.18911777631555338	[625]	[375]	1	hSpCas9	negative selection	11365978
165310631	165310654	4	+	28162770	EOL1	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.07774762579834538	[481]	[267]	0	hSpCas9	negative selection	11365979
165305693	165305716	4	+	28162770	MOLM13	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.4741348243754774	[460]	[462]	3	hSpCas9	negative selection	11535336
165311515	165311538	4	+	28162770	MOLM13	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-1.2524249720714633	[200]	[60]	-6	hSpCas9	negative selection	11535337
165313334	165313357	4	+	28162770	MOLM13	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.5841693896150715	[690]	[748]	4	hSpCas9	negative selection	11535338
165314104	165314127	4	+	28162770	MOLM13	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.2952499954052304	[265]	[235]	2	hSpCas9	negative selection	11535339
165297659	165297682	4	+	28162770	MOLM13	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.8635719481786202	[468]	[616]	6	hSpCas9	negative selection	11535340
165297696	165297719	4	-	28162770	MOLM13	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.7760116769069106	[167]	[207]	6	hSpCas9	negative selection	11535341
165299506	165299529	4	+	28162770	MOLM13	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-3.29966453245505	[285]	[20]	-8	hSpCas9	negative selection	11535342
165299613	165299636	4	+	28162770	MOLM13	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	-0.02515062973553825	[303]	[215]	0	hSpCas9	negative selection	11535343
165299647	165299670	4	-	28162770	MOLM13	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.6779585244308965	[822]	[951]	5	hSpCas9	negative selection	11535344
165310631	165310654	4	+	28162770	MOLM13	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	-0.06802869368353437	[534]	[368]	0	hSpCas9	negative selection	11535345
165305693	165305716	4	+	28162770	HEL	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.47597417145137255	[512]	[456]	4	hSpCas9	negative selection	11704702
165311515	165311538	4	+	28162770	HEL	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.3057038447227862	[95]	[75]	2	hSpCas9	negative selection	11704703
165313334	165313357	4	+	28162770	HEL	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.35493652101762097	[657]	[538]	3	hSpCas9	negative selection	11704704
165314104	165314127	4	+	28162770	HEL	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.49990405382890224	[243]	[220]	4	hSpCas9	negative selection	11704705
165297659	165297682	4	+	28162770	HEL	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.9572146231840201	[426]	[530]	8	hSpCas9	negative selection	11704706
165297696	165297719	4	-	28162770	HEL	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	1.3608264159608738	[199]	[328]	9	hSpCas9	negative selection	11704707
165299506	165299529	4	+	28162770	HEL	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-1.09750189419871	[146]	[43]	-6	hSpCas9	negative selection	11704708
165299613	165299636	4	+	28162770	HEL	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.38975809083048596	[285]	[239]	3	hSpCas9	negative selection	11704709
165299647	165299670	4	-	28162770	HEL	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.2585953406672967	[615]	[471]	2	hSpCas9	negative selection	11704710
165310631	165310654	4	+	28162770	HEL	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	-0.026580599103317226	[492]	[309]	0	hSpCas9	negative selection	11704711
165305693	165305716	4	+	28162770	MV411	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.6727433855154463	[384]	[516]	6	hSpCas9	negative selection	11874068
165311515	165311538	4	+	28162770	MV411	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.2254112444527765	[65]	[64]	2	hSpCas9	negative selection	11874069
165313334	165313357	4	+	28162770	MV411	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	-0.05622435109446866	[568]	[460]	0	hSpCas9	negative selection	11874070
165314104	165314127	4	+	28162770	MV411	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	-0.19930880822340666	[183]	[134]	-1	hSpCas9	negative selection	11874071
165297659	165297682	4	+	28162770	MV411	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.4621407065305754	[429]	[498]	4	hSpCas9	negative selection	11874072
165297696	165297719	4	-	28162770	MV411	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	-0.2650124501540131	[96]	[67]	-2	hSpCas9	negative selection	11874073
165299506	165299529	4	+	28162770	MV411	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	0.19158431604925774	[157]	[151]	1	hSpCas9	negative selection	11874074
165299613	165299636	4	+	28162770	MV411	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.05828145892025938	[235]	[206]	0	hSpCas9	negative selection	11874075
165299647	165299670	4	-	28162770	MV411	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.6913877419768579	[493]	[671]	6	hSpCas9	negative selection	11874076
165310631	165310654	4	+	28162770	MV411	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.6696705514658233	[299]	[401]	6	hSpCas9	negative selection	11874077
165305693	165305716	4	+	28162770	MONOMAC1	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.5439869636810059	[212]	[355]	5	hSpCas9	negative selection	12043434
165311515	165311538	4	+	28162770	MONOMAC1	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	1.2777427359111795	[67]	[188]	9	hSpCas9	negative selection	12043435
165313334	165313357	4	+	28162770	MONOMAC1	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.4542681484902984	[339]	[533]	4	hSpCas9	negative selection	12043436
165314104	165314127	4	+	28162770	MONOMAC1	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.783154671860266	[109]	[216]	7	hSpCas9	negative selection	12043437
165297659	165297682	4	+	28162770	MONOMAC1	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.08066724757112531	[211]	[256]	0	hSpCas9	negative selection	12043438
165297696	165297719	4	-	28162770	MONOMAC1	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.874221836110268	[78]	[165]	7	hSpCas9	negative selection	12043439
165299506	165299529	4	+	28162770	MONOMAC1	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	1.0100076099434583	[80]	[186]	8	hSpCas9	negative selection	12043440
165299613	165299636	4	+	28162770	MONOMAC1	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.057682290562236505	[144]	[172]	0	hSpCas9	negative selection	12043441
165299647	165299670	4	-	28162770	MONOMAC1	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.576242446494736	[305]	[522]	5	hSpCas9	negative selection	12043442
165310631	165310654	4	+	28162770	MONOMAC1	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.7415626082763029	[227]	[436]	7	hSpCas9	negative selection	12043443
165305693	165305716	4	+	28162770	OCIAML2	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.5846526102590285	[63]	[531]	5	hSpCas9	negative selection	12212800
165311515	165311538	4	+	28162770	OCIAML2	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	0.19233518748026834	[8]	[56]	1	hSpCas9	negative selection	12212801
165313334	165313357	4	+	28162770	OCIAML2	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	0.6710614954712071	[85]	[758]	6	hSpCas9	negative selection	12212802
165314104	165314127	4	+	28162770	OCIAML2	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	-0.4603614897883342	[34]	[140]	-4	hSpCas9	negative selection	12212803
165297659	165297682	4	+	28162770	OCIAML2	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	0.6838415237936384	[72]	[649]	6	hSpCas9	negative selection	12212804
165297696	165297719	4	-	28162770	OCIAML2	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	1.0795672573183182	[13]	[163]	8	hSpCas9	negative selection	12212805
165299506	165299529	4	+	28162770	OCIAML2	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-1.4132966501762096	[36]	[76]	-7	hSpCas9	negative selection	12212806
165299613	165299636	4	+	28162770	OCIAML2	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	0.3773670813127888	[44]	[323]	3	hSpCas9	negative selection	12212807
165299647	165299670	4	-	28162770	OCIAML2	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	0.38888895120800826	[96]	[703]	4	hSpCas9	negative selection	12212808
165310631	165310654	4	+	28162770	OCIAML2	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.297932613818384	[69]	[476]	3	hSpCas9	negative selection	12212809
165305693	165305716	4	+	28162770	OCIAML3	viability	TAGCAGAGTTGCCTTCCAGGAGG	KLHL2	ENSG00000109466	0.6677334484881101	[92]	[445]	6	hSpCas9	negative selection	12382166
165311515	165311538	4	+	28162770	OCIAML3	viability	TAGCTCCCATGAATACAAGGAGG	KLHL2	ENSG00000109466	-1.117569596381176	[22]	[31]	-7	hSpCas9	negative selection	12382167
165313334	165313357	4	+	28162770	OCIAML3	viability	TAGCAGAAATGAGCACCAGGCGG	KLHL2	ENSG00000109466	-0.3630532054842912	[143]	[337]	-3	hSpCas9	negative selection	12382168
165314104	165314127	4	+	28162770	OCIAML3	viability	ATGATCCCACCACTAACGCATGG	KLHL2	ENSG00000109466	0.7061160842448506	[39]	[196]	6	hSpCas9	negative selection	12382169
165297659	165297682	4	+	28162770	OCIAML3	viability	AGAGTTTATGGCCCGACTGATGG	KLHL2	ENSG00000109466	-0.5457985472815432	[102]	[212]	-4	hSpCas9	negative selection	12382170
165297696	165297719	4	-	28162770	OCIAML3	viability	AAATATTCCCGAGGAAGCAAAGG	KLHL2	ENSG00000109466	0.02657877012771437	[39]	[122]	0	hSpCas9	negative selection	12382171
165299506	165299529	4	+	28162770	OCIAML3	viability	GAGGGTTGAAGAGGAAGCATTGG	KLHL2	ENSG00000109466	-0.4420045468791133	[44]	[99]	-3	hSpCas9	negative selection	12382172
165299613	165299636	4	+	28162770	OCIAML3	viability	AGAGTGTCCGGACCCGGCTGAGG	KLHL2	ENSG00000109466	-0.28084975506453297	[65]	[163]	-2	hSpCas9	negative selection	12382173
165299647	165299670	4	-	28162770	OCIAML3	viability	AAACAGATCCTACTTTGGGAAGG	KLHL2	ENSG00000109466	1.0457788851415148	[141]	[884]	8	hSpCas9	negative selection	12382174
165310631	165310654	4	+	28162770	OCIAML3	viability	ACGACCCTGTGAAGGACCAGTGG	KLHL2	ENSG00000109466	0.2804614775919778	[110]	[406]	2	hSpCas9	negative selection	12382175