Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:26249
• Symbol:KLHL3
• Description:kelch like family member 3

DataSource: http://genomecrispr.dkfz.de/#!/results/KLHL3

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
137639908	137639931	5	-	26472758	Jiyoye	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.39742892953569603	[130]	[74]	-3	hSpCas9	negative selection	85402
137639023	137639046	5	+	26472758	Jiyoye	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	-0.20425933057647372	[54]	[35]	-1	hSpCas9	negative selection	85403
137658181	137658204	5	+	26472758	Jiyoye	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-1.0252093613368671	[250]	[92]	-6	hSpCas9	negative selection	85404
137639050	137639073	5	-	26472758	Jiyoye	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.4071753815058736	[297]	[297]	3	hSpCas9	negative selection	85405
137637352	137637375	5	-	26472758	Jiyoye	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	-0.36726491807899553	[454]	[265]	-3	hSpCas9	negative selection	85406
137637322	137637345	5	-	26472758	Jiyoye	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	1.8718436485093175	[24]	[68]	8	hSpCas9	negative selection	85407
137634042	137634065	5	-	26472758	Jiyoye	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	0.40717538150587274	[0]	[0]	3	hSpCas9	negative selection	85408
137628398	137628421	5	-	26472758	Jiyoye	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	1.0611795266566812	[67]	[106]	7	hSpCas9	negative selection	85409
137639115	137639138	5	-	26472758	Jiyoye	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	-0.03595442480232339	[120]	[88]	0	hSpCas9	negative selection	85410
137639098	137639121	5	+	26472758	Jiyoye	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	-0.19816861921330364	[498]	[327]	-1	hSpCas9	negative selection	85411
137639908	137639931	5	-	26472758	KBM7	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-1.1712376989438753	[621,398]	[109,99]	-7	hSpCas9	negative selection	276520
137639023	137639046	5	+	26472758	KBM7	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	-0.1794301769774212	[395,378]	[145,174]	-2	hSpCas9	negative selection	276521
137658181	137658204	5	+	26472758	KBM7	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.2770577198090826	[776,492]	[387,325]	3	hSpCas9	negative selection	276522
137639050	137639073	5	-	26472758	KBM7	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.39763839567164316	[1409,1284]	[782,880]	4	hSpCas9	negative selection	276523
137637352	137637375	5	-	26472758	KBM7	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.5459246438166401	[1075,942]	[829,567]	6	hSpCas9	negative selection	276524
137637322	137637345	5	-	26472758	KBM7	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.3909011047878471	[264,166]	[201,66]	4	hSpCas9	negative selection	276525
137634042	137634065	5	-	26472758	KBM7	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	0.4485988279227717	[0,1]	[0,0]	5	hSpCas9	negative selection	276526
137628398	137628421	5	-	26472758	KBM7	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.042211251100876895	[614,494]	[178,316]	0	hSpCas9	negative selection	276527
137639115	137639138	5	-	26472758	KBM7	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	-0.060727808503795215	[406,498]	[219,195]	0	hSpCas9	negative selection	276528
137639098	137639121	5	+	26472758	KBM7	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.03965711495736368	[1638,1410]	[593,860]	0	hSpCas9	negative selection	276529
137639908	137639931	5	-	26472758	Raji	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	0.6939863944760112	[292]	[109]	6	hSpCas9	negative selection	467638
137639023	137639046	5	+	26472758	Raji	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	1.272807144580971	[106]	[59]	9	hSpCas9	negative selection	467639
137658181	137658204	5	+	26472758	Raji	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-0.21454455951376272	[409]	[81]	-2	hSpCas9	negative selection	467640
137639050	137639073	5	-	26472758	Raji	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.533518743535774	[517]	[173]	5	hSpCas9	negative selection	467641
137637352	137637375	5	-	26472758	Raji	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.21317819939619642	[367]	[98]	2	hSpCas9	negative selection	467642
137637322	137637345	5	-	26472758	Raji	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.44687000164526636	[97]	[30]	4	hSpCas9	negative selection	467643
137634042	137634065	5	-	26472758	Raji	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	2.1073835353735992	[0]	[0]	9	hSpCas9	negative selection	467644
137628398	137628421	5	-	26472758	Raji	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.2574531509830537	[272]	[52]	-2	hSpCas9	negative selection	467645
137639115	137639138	5	-	26472758	Raji	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.3000286133159953	[202]	[57]	3	hSpCas9	negative selection	467646
137639098	137639121	5	+	26472758	Raji	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.24441463810499608	[832]	[228]	2	hSpCas9	negative selection	467647
137639908	137639931	5	-	26472758	K562	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-1.7404743799433446	[569]	[143]	-7	hSpCas9	negative selection	658756
137639023	137639046	5	+	26472758	K562	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	-0.7234008665844034	[265]	[135]	-4	hSpCas9	negative selection	658757
137658181	137658204	5	+	26472758	K562	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.3539251345322325	[595]	[642]	2	hSpCas9	negative selection	658758
137639050	137639073	5	-	26472758	K562	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.823357440759833	[959]	[1433]	7	hSpCas9	negative selection	658759
137637352	137637375	5	-	26472758	K562	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.37868214569014613	[850]	[933]	3	hSpCas9	negative selection	658760
137637322	137637345	5	-	26472758	K562	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	-0.562936194391157	[223]	[127]	-4	hSpCas9	negative selection	658761
137634042	137634065	5	-	26472758	K562	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	0.24441872766644757	[0]	[0]	2	hSpCas9	negative selection	658762
137628398	137628421	5	-	26472758	K562	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	0.24760700529749444	[451]	[452]	2	hSpCas9	negative selection	658763
137639115	137639138	5	-	26472758	K562	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	-0.028159450838217914	[272]	[225]	0	hSpCas9	negative selection	658764
137639098	137639121	5	+	26472758	K562	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	-0.09999686862359014	[1082]	[852]	0	hSpCas9	negative selection	658765
137658130	137658153	5	-	26627737	DLD1	viability	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.0955824112300927	[200]	[21,20,121]	-1	hSpCas9	negative selection	826975
137661922	137661945	5	+	26627737	DLD1	viability	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.09365885604759164	[447]	[91,261,105]	1	hSpCas9	negative selection	826976
137677595	137677618	5	-	26627737	DLD1	viability	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-0.7423147980549595	[486]	[64,52,144]	-6	hSpCas9	negative selection	826977
137692284	137692307	5	-	26627737	DLD1	viability	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.7666352421725723	[704]	[156,127,106]	-6	hSpCas9	negative selection	826978
137709780	137709803	5	+	26627737	DLD1	viability	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.7157939803737764	[1493]	[224,364,268]	-6	hSpCas9	negative selection	826979
137720464	137720487	5	-	26627737	DLD1	viability	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.28488279259019167	[294]	[127,99,108]	3	hSpCas9	negative selection	826980
137658130	137658153	5	-	26627737	GBM cells	viability after 5 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.3115059047846863	[139]	[82,37]	-5	hSpCas9	negative selection	909290
137661922	137661945	5	+	26627737	GBM cells	viability after 5 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.05818039482927567	[316]	[165,187]	0	hSpCas9	negative selection	909291
137677595	137677618	5	-	26627737	GBM cells	viability after 5 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-0.3189911554584485	[213]	[113,69]	-5	hSpCas9	negative selection	909292
137692284	137692307	5	-	26627737	GBM cells	viability after 5 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.027295864399955683	[342]	[204,155]	0	hSpCas9	negative selection	909293
137709780	137709803	5	+	26627737	GBM cells	viability after 5 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.3558273241486227	[450]	[196,180]	-5	hSpCas9	negative selection	909294
137720464	137720487	5	-	26627737	GBM cells	viability after 5 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	-0.514193597294759	[248]	[112,73]	-7	hSpCas9	negative selection	909295
137658130	137658153	5	-	26627737	GBM cells	viability after 13 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.32376501160982396	[139]	[63,57]	-4	hSpCas9	negative selection	991605
137661922	137661945	5	+	26627737	GBM cells	viability after 13 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.039870552548932625	[316]	[226,135]	0	hSpCas9	negative selection	991606
137677595	137677618	5	-	26627737	GBM cells	viability after 13 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-0.09166622800784541	[213]	[103,112]	-1	hSpCas9	negative selection	991607
137692284	137692307	5	-	26627737	GBM cells	viability after 13 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.19351309094277508	[342]	[202,129]	-2	hSpCas9	negative selection	991608
137709780	137709803	5	+	26627737	GBM cells	viability after 13 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.5348172982345638	[450]	[185,154]	-6	hSpCas9	negative selection	991609
137720464	137720487	5	-	26627737	GBM cells	viability after 13 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	-0.32881811618570195	[248]	[138,81]	-4	hSpCas9	negative selection	991610
137658130	137658153	5	-	26627737	GBM cells	viability after 21 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.9460808403277606	[139]	[39,38]	-7	hSpCas9	negative selection	1073920
137661922	137661945	5	+	26627737	GBM cells	viability after 21 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.059259794241435904	[316]	[181,149]	0	hSpCas9	negative selection	1073921
137677595	137677618	5	-	26627737	GBM cells	viability after 21 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.09786668159782937	[213]	[137,111]	1	hSpCas9	negative selection	1073922
137692284	137692307	5	-	26627737	GBM cells	viability after 21 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.6238958796416434	[342]	[110,129]	-5	hSpCas9	negative selection	1073923
137709780	137709803	5	+	26627737	GBM cells	viability after 21 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	0.0657521835634477	[450]	[245,265]	0	hSpCas9	negative selection	1073924
137720464	137720487	5	-	26627737	GBM cells	viability after 21 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	-0.5435430060772101	[248]	[108,77]	-5	hSpCas9	negative selection	1073925
137658130	137658153	5	-	26627737	RPE1	viability after 9 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.536057574878892	[439]	[63,134]	-4	hSpCas9	negative selection	1156235
137661922	137661945	5	+	26627737	RPE1	viability after 9 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.42474149771989683	[810]	[249,457]	3	hSpCas9	negative selection	1156236
137677595	137677618	5	-	26627737	RPE1	viability after 9 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	2.573322585165282	[141]	[216,325]	9	hSpCas9	negative selection	1156237
137692284	137692307	5	-	26627737	RPE1	viability after 9 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.18422213597622733	[825]	[202,410]	1	hSpCas9	negative selection	1156238
137709780	137709803	5	+	26627737	RPE1	viability after 9 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	1.53045760173584	[349]	[240,413]	8	hSpCas9	negative selection	1156239
137720464	137720487	5	-	26627737	RPE1	viability after 9 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.005669515623890231	[595]	[192,179]	0	hSpCas9	negative selection	1156240
137658130	137658153	5	-	26627737	RPE1	viability after 12 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.34919540161131213	[439]	[85,99]	-2	hSpCas9	negative selection	1238550
137661922	137661945	5	+	26627737	RPE1	viability after 12 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.7326269105905081	[810]	[244,485]	5	hSpCas9	negative selection	1238551
137677595	137677618	5	-	26627737	RPE1	viability after 12 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	2.0522306135904196	[141]	[182,131]	9	hSpCas9	negative selection	1238552
137692284	137692307	5	-	26627737	RPE1	viability after 12 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.3042959528104024	[825]	[240,308]	2	hSpCas9	negative selection	1238553
137709780	137709803	5	+	26627737	RPE1	viability after 12 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	1.1455381767681325	[349]	[157,260]	7	hSpCas9	negative selection	1238554
137720464	137720487	5	-	26627737	RPE1	viability after 12 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.005040753338544979	[595]	[200,117]	0	hSpCas9	negative selection	1238555
137658130	137658153	5	-	26627737	RPE1	viability after 15 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-1.67153293662791	[439]	[34,42]	-7	hSpCas9	negative selection	1320865
137661922	137661945	5	+	26627737	RPE1	viability after 15 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.2643954380187633	[810]	[187,359]	1	hSpCas9	negative selection	1320866
137677595	137677618	5	-	26627737	RPE1	viability after 15 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	2.416196342249626	[141]	[275,154]	9	hSpCas9	negative selection	1320867
137692284	137692307	5	-	26627737	RPE1	viability after 15 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.19804712384132073	[825]	[293,242]	1	hSpCas9	negative selection	1320868
137709780	137709803	5	+	26627737	RPE1	viability after 15 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	1.1795674341194629	[349]	[293,156]	6	hSpCas9	negative selection	1320869
137720464	137720487	5	-	26627737	RPE1	viability after 15 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.1630428777899943	[595]	[229,148]	1	hSpCas9	negative selection	1320870
137658130	137658153	5	-	26627737	RPE1	viability after 18 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.867011291736399	[439]	[38,92]	-5	hSpCas9	negative selection	1403180
137661922	137661945	5	+	26627737	RPE1	viability after 18 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.5477818248364147	[810]	[259,383]	3	hSpCas9	negative selection	1403181
137677595	137677618	5	-	26627737	RPE1	viability after 18 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	2.548435515617828	[141]	[243,202]	9	hSpCas9	negative selection	1403182
137692284	137692307	5	-	26627737	RPE1	viability after 18 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.40990881962327724	[825]	[329,259]	2	hSpCas9	negative selection	1403183
137709780	137709803	5	+	26627737	RPE1	viability after 18 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	0.9289421126407555	[349]	[203,153]	5	hSpCas9	negative selection	1403184
137720464	137720487	5	-	26627737	RPE1	viability after 18 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.0007369628027770747	[595]	[216,100]	0	hSpCas9	negative selection	1403185
137658130	137658153	5	-	26627737	HeLa	viability after 8 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	1.1409043333061928	[111]	[142,105,82]	8	hSpCas9	negative selection	1485495
137661922	137661945	5	+	26627737	HeLa	viability after 8 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	1.1414071655445632	[273]	[377,197,239]	8	hSpCas9	negative selection	1485496
137677595	137677618	5	-	26627737	HeLa	viability after 8 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	1.4011916091267655	[139]	[242,129,129]	8	hSpCas9	negative selection	1485497
137692284	137692307	5	-	26627737	HeLa	viability after 8 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.12032117637277352	[450]	[287,225,59]	-1	hSpCas9	negative selection	1485498
137709780	137709803	5	+	26627737	HeLa	viability after 8 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-1.4625842251033934	[933]	[207,59,184]	-9	hSpCas9	negative selection	1485499
137720464	137720487	5	-	26627737	HeLa	viability after 8 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.5873384122438643	[241]	[103,189,167]	5	hSpCas9	negative selection	1485500
137658130	137658153	5	-	26627737	HeLa	viability after 12 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-1.037214837169677	[111]	[0,3,63]	-7	hSpCas9	negative selection	1567810
137661922	137661945	5	+	26627737	HeLa	viability after 12 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.5058347368975812	[273]	[134,175,168]	4	hSpCas9	negative selection	1567811
137677595	137677618	5	-	26627737	HeLa	viability after 12 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.46213387189657973	[139]	[110,60,69]	4	hSpCas9	negative selection	1567812
137692284	137692307	5	-	26627737	HeLa	viability after 12 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.6221311619108814	[450]	[148,121,92]	-5	hSpCas9	negative selection	1567813
137709780	137709803	5	+	26627737	HeLa	viability after 12 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.505133801876499	[933]	[231,193,396]	-4	hSpCas9	negative selection	1567814
137720464	137720487	5	-	26627737	HeLa	viability after 12 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.4519938175409895	[241]	[94,100,216]	4	hSpCas9	negative selection	1567815
137658130	137658153	5	-	26627737	HeLa	viability after 15 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	0.09741228822885195	[111]	[9,61,76]	0	hSpCas9	negative selection	1650125
137661922	137661945	5	+	26627737	HeLa	viability after 15 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.9105869375562303	[273]	[179,232,216]	7	hSpCas9	negative selection	1650126
137677595	137677618	5	-	26627737	HeLa	viability after 15 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.9945651440737868	[139]	[157,93,85]	7	hSpCas9	negative selection	1650127
137692284	137692307	5	-	26627737	HeLa	viability after 15 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.5591523102213776	[450]	[231,261,321]	4	hSpCas9	negative selection	1650128
137709780	137709803	5	+	26627737	HeLa	viability after 15 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.6464695691885453	[933]	[226,221,282]	-5	hSpCas9	negative selection	1650129
137720464	137720487	5	-	26627737	HeLa	viability after 15 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	-0.5368085430832288	[241]	[136,7,56]	-5	hSpCas9	negative selection	1650130
137658130	137658153	5	-	26627737	HeLa	viability after 18 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	0.07936238881149404	[111]	[4,51,76]	0	hSpCas9	negative selection	1732440
137661922	137661945	5	+	26627737	HeLa	viability after 18 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.9277522028753642	[273]	[127,189,216]	7	hSpCas9	negative selection	1732441
137677595	137677618	5	-	26627737	HeLa	viability after 18 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	1.0186562685636638	[139]	[107,79,85]	7	hSpCas9	negative selection	1732442
137692284	137692307	5	-	26627737	HeLa	viability after 18 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.5541574860193885	[450]	[164,202,321]	4	hSpCas9	negative selection	1732443
137709780	137709803	5	+	26627737	HeLa	viability after 18 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.6173525069271315	[933]	[160,184,282]	-5	hSpCas9	negative selection	1732444
137720464	137720487	5	-	26627737	HeLa	viability after 18 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	-0.4897673879158715	[241]	[95,6,56]	-4	hSpCas9	negative selection	1732445
137658130	137658153	5	-	26627737	HCT116	viability after 6 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	0.7965118536474736	[183]	[66,40]	4	hSpCas9	negative selection	1814755
137661922	137661945	5	+	26627737	HCT116	viability after 6 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-2.3207640182154705	[1042]	[46,24]	-8	hSpCas9	negative selection	1814756
137677595	137677618	5	-	26627737	HCT116	viability after 6 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-0.5140596998051552	[719]	[115,58]	-3	hSpCas9	negative selection	1814757
137692284	137692307	5	-	26627737	HCT116	viability after 6 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.8131782475033773	[796]	[107,281]	4	hSpCas9	negative selection	1814758
137709780	137709803	5	+	26627737	HCT116	viability after 6 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.053059919626222696	[1846]	[217,313]	0	hSpCas9	negative selection	1814759
137720464	137720487	5	-	26627737	HCT116	viability after 6 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.028187320888939715	[388]	[169,2]	0	hSpCas9	negative selection	1814760
137658130	137658153	5	-	26627737	HCT116	viability after 8 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.6149626454208199	[153]	[32,91,40]	-6	hSpCas9	negative selection	1897070
137661922	137661945	5	+	26627737	HCT116	viability after 8 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.05378437247128656	[349]	[176,173,205]	0	hSpCas9	negative selection	1897071
137677595	137677618	5	-	26627737	HCT116	viability after 8 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.660512876729122	[193]	[169,173,162]	6	hSpCas9	negative selection	1897072
137692284	137692307	5	-	26627737	HCT116	viability after 8 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.7924365468041245	[178]	[177,111,221]	7	hSpCas9	negative selection	1897073
137709780	137709803	5	+	26627737	HCT116	viability after 8 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	0.2958785755587694	[510]	[265,457,311]	3	hSpCas9	negative selection	1897074
137720464	137720487	5	-	26627737	HCT116	viability after 8 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.8091758492095046	[151]	[190,97,151]	7	hSpCas9	negative selection	1897075
137658130	137658153	5	-	26627737	HCT116	viability after 9 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-2.4158085301160286	[183]	[11,6]	-9	hSpCas9	negative selection	1979385
137661922	137661945	5	+	26627737	HCT116	viability after 9 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.5068237870510889	[1042]	[257,146]	-4	hSpCas9	negative selection	1979386
137677595	137677618	5	-	26627737	HCT116	viability after 9 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.9856918565440168	[719]	[268,468]	6	hSpCas9	negative selection	1979387
137692284	137692307	5	-	26627737	HCT116	viability after 9 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.9300318683275905	[796]	[481,344]	6	hSpCas9	negative selection	1979388
137709780	137709803	5	+	26627737	HCT116	viability after 9 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	0.16616761306538352	[1846]	[501,593]	1	hSpCas9	negative selection	1979389
137720464	137720487	5	-	26627737	HCT116	viability after 9 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	-0.13179395951822526	[388]	[110,81]	-1	hSpCas9	negative selection	1979390
137658130	137658153	5	-	26627737	HCT116	viability after 12 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.6259806989007526	[153]	[15,71,72]	-6	hSpCas9	negative selection	2061700
137661922	137661945	5	+	26627737	HCT116	viability after 12 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.4535886484534816	[349]	[85,167,153]	-5	hSpCas9	negative selection	2061701
137677595	137677618	5	-	26627737	HCT116	viability after 12 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.9365832086301857	[193]	[284,173,117]	7	hSpCas9	negative selection	2061702
137692284	137692307	5	-	26627737	HCT116	viability after 12 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	1.3319384006490829	[178]	[429,93,165]	8	hSpCas9	negative selection	2061703
137709780	137709803	5	+	26627737	HCT116	viability after 12 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	0.6181925032211635	[510]	[486,451,291]	6	hSpCas9	negative selection	2061704
137720464	137720487	5	-	26627737	HCT116	viability after 12 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.6347646375285907	[151]	[142,147,79]	6	hSpCas9	negative selection	2061705
137658130	137658153	5	-	26627737	HCT116	viability after 15 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-1.9012170525719847	[153]	[0,20,45]	-9	hSpCas9	negative selection	2144015
137661922	137661945	5	+	26627737	HCT116	viability after 15 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.22477114442763782	[349]	[175,126,212]	-2	hSpCas9	negative selection	2144016
137677595	137677618	5	-	26627737	HCT116	viability after 15 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.2949337042846064	[193]	[245,93,83]	3	hSpCas9	negative selection	2144017
137692284	137692307	5	-	26627737	HCT116	viability after 15 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	1.46877392860406	[178]	[442,154,274]	9	hSpCas9	negative selection	2144018
137709780	137709803	5	+	26627737	HCT116	viability after 15 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	0.4234093841791098	[510]	[464,381,342]	4	hSpCas9	negative selection	2144019
137720464	137720487	5	-	26627737	HCT116	viability after 15 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.2178410776414773	[151]	[121,78,105]	2	hSpCas9	negative selection	2144020
137658130	137658153	5	-	26627737	HCT116	viability after 18 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.7165808604607731	[153]	[0,19,119]	-6	hSpCas9	negative selection	2226330
137661922	137661945	5	+	26627737	HCT116	viability after 18 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.45793852311347194	[349]	[65,82,227]	-4	hSpCas9	negative selection	2226331
137677595	137677618	5	-	26627737	HCT116	viability after 18 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.57958045889144	[193]	[63,166,189]	5	hSpCas9	negative selection	2226332
137692284	137692307	5	-	26627737	HCT116	viability after 18 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	1.216354099174188	[178]	[283,91,235]	8	hSpCas9	negative selection	2226333
137709780	137709803	5	+	26627737	HCT116	viability after 18 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	0.9938888360765588	[510]	[662,515,285]	7	hSpCas9	negative selection	2226334
137720464	137720487	5	-	26627737	HCT116	viability after 18 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.20217991456540285	[151]	[53,50,153]	1	hSpCas9	negative selection	2226335
137721424	137721447	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AACAAAGTAGGACAGAAAGCAGG	KLHL3	ENSG00000146021	1.5053333105302453	[63,101]	[18,86]	5	dCas9-VP64	positive selection	2416634
137721470	137721493	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATCACATTGGCTACACTCCAGG	KLHL3	ENSG00000146021	3.0721028852875514	[130,79]	[210,176]	8	dCas9-VP64	positive selection	2416635
137721488	137721511	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGTTGTTCGACTGCTTCCTGG	KLHL3	ENSG00000146021	-0.8514419270623298	[257,252]	[56,2]	-5	dCas9-VP64	positive selection	2416636
137706532	137706555	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AATCGAGTACTTCTTATTCTAGG	KLHL3	ENSG00000146021	-0.5725356963561796	[239,395]	[29,64]	-3	dCas9-VP64	positive selection	2416637
137706732	137706755	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAACTGCAATTTCATTGACATGG	KLHL3	ENSG00000146021	-1.409975064437579	[109,46]	[4,6]	-7	dCas9-VP64	positive selection	2416638
137706661	137706684	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAAAATTCATTTCCTTCGTTGG	KLHL3	ENSG00000146021	0.6456923592214849	[153,155]	[30,76]	2	dCas9-VP64	positive selection	2416639
137631088	137631111	5	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAAGAGAGAGAGAGAGAGAAAGG	KLHL3	ENSG00000146021	0.6316515901792452	[28,11]	[9,2]	2	dCas9-VP64	positive selection	2441191
137697362	137697385	5	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGAAACCAGCCTGGCCAACACAG	KLHL3	ENSG00000146021	0.4780801974693999	[28,77]	[7,24]	2	dCas9-VP64	positive selection	2472842
137721424	137721447	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AACAAAGTAGGACAGAAAGCAGG	KLHL3	ENSG00000146021	-0.5918202359480538	[240,200]	[63,31]	-6	dCas9-VP64	positive selection	2511889
137721470	137721493	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATCACATTGGCTACACTCCAGG	KLHL3	ENSG00000146021	-0.4706679336240672	[185,276]	[35,70]	-5	dCas9-VP64	positive selection	2511890
137721488	137721511	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGTTGTTCGACTGCTTCCTGG	KLHL3	ENSG00000146021	0.6595798230532947	[80,74]	[50,29]	5	dCas9-VP64	positive selection	2511891
137706532	137706555	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AATCGAGTACTTCTTATTCTAGG	KLHL3	ENSG00000146021	-0.2892417546371917	[315,363]	[113,68]	-3	dCas9-VP64	positive selection	2511892
137706732	137706755	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAACTGCAATTTCATTGACATGG	KLHL3	ENSG00000146021	-0.16391985310619664	[168,85]	[22,49]	-1	dCas9-VP64	positive selection	2511893
137706661	137706684	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAAAATTCATTTCCTTCGTTGG	KLHL3	ENSG00000146021	-0.5118817628899177	[65,373]	[26,69]	-5	dCas9-VP64	positive selection	2511894
137631088	137631111	5	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAAGAGAGAGAGAGAGAGAAAGG	KLHL3	ENSG00000146021	0.43533825533627796	[75,43]	[28,22]	3	dCas9-VP64	positive selection	2536446
137697362	137697385	5	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGAAACCAGCCTGGCCAACACAG	KLHL3	ENSG00000146021	0.26160550637758195	[116,79]	[45,30]	2	dCas9-VP64	positive selection	2568097
137658182	137658205	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-0.60858264291896	[3,2]	[2,0]	-7	hSpCas9	positive selection	2997821
137639908	137639931	5	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.3485373428466696	[3,2]	[3,0]	-5	hSpCas9	positive selection	2997822
137658179	137658202	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCAATAGTCTCTGATCCAGAGGG	KLHL3	ENSG00000146021	-0.25827785735529807	[3,3]	[3,1]	-4	hSpCas9	positive selection	2997823
137692325	137692348	5	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTGTACATCTGCAAATGCACGG	KLHL3	ENSG00000146021	0.09626982218918911	[4,4]	[3,3]	2	hSpCas9	positive selection	2997824
137658182	137658205	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-0.6616707118561713	[3,3]	[2,0]	-8	hSpCas9	positive selection	3065679
137639908	137639931	5	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.7630331822536454	[3,3]	[1,0]	-8	hSpCas9	positive selection	3065680
137658179	137658202	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCAATAGTCTCTGATCCAGAGGG	KLHL3	ENSG00000146021	-0.006015887902471279	[3,3]	[2,1]	0	hSpCas9	positive selection	3065681
137692325	137692348	5	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTGTACATCTGCAAATGCACGG	KLHL3	ENSG00000146021	0.03463467522784272	[4,4]	[3,2]	0	hSpCas9	positive selection	3065682
137661913	137661936		+	24336571	A375	resistance to PLX after 7 days	ACTTGGACTAGGTAGTCCCTAGG	KLHL3	ENSG00000146021	-0.12269341945708545	[22,22]	[21,19]	-4	hSpCas9	positive selection	3123459
137720484	137720507		-	24336571	A375	resistance to PLX after 7 days	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	-0.11339636127860242	[8,7]	[7,7]	-4	hSpCas9	positive selection	3123460
137720547	137720570		+	24336571	A375	resistance to PLX after 7 days	CCCCAGCCTGTATCAGAGTCTGG	KLHL3	ENSG00000146021	-0.1606831195424917	[18,15]	[15,15]	-5	hSpCas9	positive selection	3123461
137735632	137735655		-	24336571	A375	resistance to PLX after 7 days	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	0.07459156960141211	[14,18]	[16,17]	2	hSpCas9	positive selection	3123462
137658220	137658243		-	24336571	A375	resistance to PLX after 7 days	CTGTAAAGACTTCCTCATTGAGG	KLHL3	ENSG00000146021	-0.17000135781496806	[8,11]	[8,8]	-5	hSpCas9	positive selection	3123463
137658126	137658149		+	24336571	A375	resistance to PLX after 7 days	CTTACCTTGGGAAGGCTGACTGG	KLHL3	ENSG00000146021	-0.06504785748003994	[16,13]	[14,14]	-2	hSpCas9	positive selection	3123464
137720511	137720534		+	24336571	A375	resistance to PLX after 7 days	GGTTGACAGTGATCGTCCTCTGG	KLHL3	ENSG00000146021	0.015215649380509177	[7,11]	[9,8]	0	hSpCas9	positive selection	3123465
137661930	137661953		-	24336571	A375	resistance to PLX after 7 days	TCCGACTTCCTCTCTTACCTAGG	KLHL3	ENSG00000146021	-0.2390642957008372	[21,23]	[17,19]	-7	hSpCas9	positive selection	3123466
137709751	137709774		+	24336571	A375	resistance to PLX after 7 days	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.03329371375045023	[10,11]	[9,12]	1	hSpCas9	positive selection	3123468
137661913	137661936		+	24336571	A375	resistance to PLX after 14 days	ACTTGGACTAGGTAGTCCCTAGG	KLHL3	ENSG00000146021	-0.5768208132483116	[19,23]	[5,6]	-6	hSpCas9	positive selection	3181252
137720484	137720507		-	24336571	A375	resistance to PLX after 14 days	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	-0.49112586856298945	[8,7]	[2,1]	-6	hSpCas9	positive selection	3181253
137720547	137720570		+	24336571	A375	resistance to PLX after 14 days	CCCCAGCCTGTATCAGAGTCTGG	KLHL3	ENSG00000146021	-0.6174814736135531	[19,21]	[5,5]	-7	hSpCas9	positive selection	3181254
137735632	137735655		-	24336571	A375	resistance to PLX after 14 days	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	0.01984816700797408	[12,13]	[6,5]	0	hSpCas9	positive selection	3181255
137658220	137658243		-	24336571	A375	resistance to PLX after 14 days	CTGTAAAGACTTCCTCATTGAGG	KLHL3	ENSG00000146021	-0.7400941533283378	[6,11]	[1,1]	-8	hSpCas9	positive selection	3181256
137658126	137658149		+	24336571	A375	resistance to PLX after 14 days	CTTACCTTGGGAAGGCTGACTGG	KLHL3	ENSG00000146021	-0.5148438475417617	[9,14]	[3,3]	-6	hSpCas9	positive selection	3181257
137720511	137720534		+	24336571	A375	resistance to PLX after 14 days	GGTTGACAGTGATCGTCCTCTGG	KLHL3	ENSG00000146021	-0.266736715043689	[7,6]	[2,1]	-3	hSpCas9	positive selection	3181258
137661930	137661953		-	24336571	A375	resistance to PLX after 14 days	TCCGACTTCCTCTCTTACCTAGG	KLHL3	ENSG00000146021	-1.032295368892823	[23,24]	[4,5]	-9	hSpCas9	positive selection	3181259
137709751	137709774		+	24336571	A375	resistance to PLX after 14 days	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.0435613460531936	[14,11]	[4,7]	0	hSpCas9	positive selection	3181261
137661913	137661936		+	24336571	A375	viability after 7 days	ACTTGGACTAGGTAGTCCCTAGG	KLHL3	ENSG00000146021	0.532671751121602	[16]	[22,22]	7	hSpCas9	negative selection	3239045
137720484	137720507		-	24336571	A375	viability after 7 days	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.4586353214310668	[6]	[8,7]	7	hSpCas9	negative selection	3239046
137720547	137720570		+	24336571	A375	viability after 7 days	CCCCAGCCTGTATCAGAGTCTGG	KLHL3	ENSG00000146021	0.28060779520546075	[14]	[18,15]	4	hSpCas9	negative selection	3239047
137735632	137735655		-	24336571	A375	viability after 7 days	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	0.3206180135514115	[13]	[14,18]	5	hSpCas9	negative selection	3239048
137658220	137658243		-	24336571	A375	viability after 7 days	CTGTAAAGACTTCCTCATTGAGG	KLHL3	ENSG00000146021	-0.24291690593323226	[12]	[8,11]	-3	hSpCas9	negative selection	3239049
137658126	137658149		+	24336571	A375	viability after 7 days	CTTACCTTGGGAAGGCTGACTGG	KLHL3	ENSG00000146021	0.07159946335760939	[15]	[16,13]	1	hSpCas9	negative selection	3239050
137720511	137720534		+	24336571	A375	viability after 7 days	GGTTGACAGTGATCGTCCTCTGG	KLHL3	ENSG00000146021	0.06225869383373278	[9]	[7,11]	0	hSpCas9	negative selection	3239051
137661930	137661953		-	24336571	A375	viability after 7 days	TCCGACTTCCTCTCTTACCTAGG	KLHL3	ENSG00000146021	0.18213879580871783	[20]	[21,23]	2	hSpCas9	negative selection	3239052
137709751	137709774		+	24336571	A375	viability after 7 days	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.6220397347987267	[7]	[10,11]	8	hSpCas9	negative selection	3239054
137661913	137661936		+	24336571	A375	viability after 14 days	ACTTGGACTAGGTAGTCCCTAGG	KLHL3	ENSG00000146021	0.491152977439973	[16]	[19,23]	6	hSpCas9	negative selection	3296838
137720484	137720507		-	24336571	A375	viability after 14 days	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.39447552146264486	[6]	[8,7]	5	hSpCas9	negative selection	3296839
137720547	137720570		+	24336571	A375	viability after 14 days	CCCCAGCCTGTATCAGAGTCTGG	KLHL3	ENSG00000146021	0.535908343489784	[14]	[19,21]	6	hSpCas9	negative selection	3296840
137735632	137735655		-	24336571	A375	viability after 14 days	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	0.04936874044795139	[13]	[12,13]	0	hSpCas9	negative selection	3296841
137658220	137658243		-	24336571	A375	viability after 14 days	CTGTAAAGACTTCCTCATTGAGG	KLHL3	ENSG00000146021	-0.35464543921178365	[12]	[6,11]	-4	hSpCas9	negative selection	3296842
137658126	137658149		+	24336571	A375	viability after 14 days	CTTACCTTGGGAAGGCTGACTGG	KLHL3	ENSG00000146021	-0.18408455524759945	[15]	[9,14]	-2	hSpCas9	negative selection	3296843
137720511	137720534		+	24336571	A375	viability after 14 days	GGTTGACAGTGATCGTCCTCTGG	KLHL3	ENSG00000146021	-0.2316995897360669	[9]	[7,6]	-3	hSpCas9	negative selection	3296844
137661930	137661953		-	24336571	A375	viability after 14 days	TCCGACTTCCTCTCTTACCTAGG	KLHL3	ENSG00000146021	0.2885258678111121	[20]	[23,24]	4	hSpCas9	negative selection	3296845
137709751	137709774		+	24336571	A375	viability after 14 days	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.8968515500394991	[7]	[14,11]	9	hSpCas9	negative selection	3296847
137735632	137735655	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	0.9353981165584727	[79,79]	[0,0]	4	hSpCas9	positive selection	3376031
137709749	137709772	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	1.1912370209880627	[66,66]	[0,0]	5	hSpCas9	positive selection	3376032
137709825	137709848	5	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.9025451253325543	[285,285]	[0,0]	-6	hSpCas9	positive selection	3376033
137658181	137658204	5	+	26780180	HT29	viability (Avana library 4 designs)	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	1.08238003936908	[]	[]	4	hSpCas9	negative selection	3435263
137639908	137639931	5	-	26780180	HT29	viability (Avana library 4 designs)	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	4.14548844150443	[]	[]	9	hSpCas9	negative selection	3435264
137658178	137658201	5	+	26780180	HT29	viability (Avana library 4 designs)	TCAATAGTCTCTGATCCAGAGGG	KLHL3	ENSG00000146021	0.645066460113624	[]	[]	2	hSpCas9	negative selection	3435265
137692324	137692347	5	+	26780180	HT29	viability (Avana library 4 designs)	TGTGTACATCTGCAAATGCACGG	KLHL3	ENSG00000146021	0.663794801073941	[]	[]	2	hSpCas9	negative selection	3435266
137639908	137639931	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-2.69568678415879	[]	[]	-3	hSpCas9	negative selection	3522752
137658181	137658204	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	1.00092143116048	[]	[]	1	hSpCas9	negative selection	3522753
137658178	137658201	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCAATAGTCTCTGATCCAGAGGG	KLHL3	ENSG00000146021	-11.2059869649315	[]	[]	-8	hSpCas9	negative selection	3522754
137692324	137692347	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTGTACATCTGCAAATGCACGG	KLHL3	ENSG00000146021	1.21381796864652	[]	[]	1	hSpCas9	negative selection	3522755
137639899	137639922	5	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGATTTCGAGGAGGACCGGTGGG	KLHL3	ENSG00000146021	2.47739292909163	[]	[]	3	hSpCas9	negative selection	3522756
137639917	137639940	5	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATCATAGCACTCCACACTGCGG	KLHL3	ENSG00000146021	-3.42025734683231	[]	[]	-4	hSpCas9	negative selection	3522757
137639908	137639931	5	-	26780180	A375	viability (Avana lentiGuide)	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	11.9176284773471	[]	[]	7	hSpCas9	negative selection	3631411
137658181	137658204	5	+	26780180	A375	viability (Avana lentiGuide)	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-4.62033497508877	[]	[]	-7	hSpCas9	negative selection	3631412
137658178	137658201	5	+	26780180	A375	viability (Avana lentiGuide)	TCAATAGTCTCTGATCCAGAGGG	KLHL3	ENSG00000146021	-2.21266968648991	[]	[]	-4	hSpCas9	negative selection	3631413
137692324	137692347	5	+	26780180	A375	viability (Avana lentiGuide)	TGTGTACATCTGCAAATGCACGG	KLHL3	ENSG00000146021	-2.28590448341825	[]	[]	-4	hSpCas9	negative selection	3631414
137639899	137639922	5	-	26780180	A375	viability (Avana lentiGuide)	TGATTTCGAGGAGGACCGGTGGG	KLHL3	ENSG00000146021	0.974331821920647	[]	[]	1	hSpCas9	negative selection	3631415
137639917	137639940	5	+	26780180	A375	viability (Avana lentiGuide)	AATCATAGCACTCCACACTGCGG	KLHL3	ENSG00000146021	-1.22206145739595	[]	[]	-2	hSpCas9	negative selection	3631416
137639908	137639931	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.5886304521997268	[5]	[3,2]	-7	hSpCas9	positive selection	3740070
137658181	137658204	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-0.04026499373225101	[5]	[6,4]	0	hSpCas9	positive selection	3740071
137658178	137658201	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCAATAGTCTCTGATCCAGAGGG	KLHL3	ENSG00000146021	-0.7515902325934842	[7]	[3,4]	-8	hSpCas9	positive selection	3740072
137692324	137692347	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTGTACATCTGCAAATGCACGG	KLHL3	ENSG00000146021	0.05819629974195317	[6]	[6,6]	1	hSpCas9	positive selection	3740073
137639899	137639922	5	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGATTTCGAGGAGGACCGGTGGG	KLHL3	ENSG00000146021	0.13230101099919125	[4]	[4,4]	3	hSpCas9	positive selection	3740074
137639917	137639940	5	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCATAGCACTCCACACTGCGG	KLHL3	ENSG00000146021	-0.30369934926045666	[6]	[5,4]	-4	hSpCas9	positive selection	3740075
137639908	137639931	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.29652500536798937	[5]	[3,3]	-4	hSpCas9	positive selection	3848677
137658181	137658204	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-0.4390565122666309	[5]	[4,1]	-5	hSpCas9	positive selection	3848678
137658178	137658201	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCAATAGTCTCTGATCCAGAGGG	KLHL3	ENSG00000146021	-0.08459494949029413	[4]	[4,3]	-1	hSpCas9	positive selection	3848679
137692324	137692347	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTGTACATCTGCAAATGCACGG	KLHL3	ENSG00000146021	0.40382127301252374	[5]	[6,6]	9	hSpCas9	positive selection	3848680
137639899	137639922	5	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGATTTCGAGGAGGACCGGTGGG	KLHL3	ENSG00000146021	0.24298692556997994	[5]	[6,5]	6	hSpCas9	positive selection	3848681
137639917	137639940	5	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCATAGCACTCCACACTGCGG	KLHL3	ENSG00000146021	0.19715083672511918	[7]	[7,6]	5	hSpCas9	positive selection	3848682
137720484	137720507	5	-	26780180	A375	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.747405925735562	[]	[]	2	hSpCas9	negative selection	3954729
137709792	137709815	5	-	26780180	A375	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.872371453431757	[]	[]	3	hSpCas9	negative selection	3954730
137735632	137735655	5	-	26780180	A375	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	1.52869071621788	[]	[]	8	hSpCas9	negative selection	3954731
137709825	137709848	5	-	26780180	A375	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.607539796184685	[]	[]	2	hSpCas9	negative selection	3954732
137709749	137709772	5	-	26780180	A375	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	1.07770537696726	[]	[]	5	hSpCas9	negative selection	3954733
137709751	137709774	5	+	26780180	A375	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.665667496504066	[]	[]	2	hSpCas9	negative selection	3954734
137720484	137720507	5	-	26780180	HT29	viability (GeCKOv2 library)	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	1.62207517211083	[]	[]	8	hSpCas9	negative selection	4062695
137709792	137709815	5	-	26780180	HT29	viability (GeCKOv2 library)	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.82705922239131	[]	[]	3	hSpCas9	negative selection	4062696
137735632	137735655	5	-	26780180	HT29	viability (GeCKOv2 library)	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	1.31943084475995	[]	[]	6	hSpCas9	negative selection	4062697
137709825	137709848	5	-	26780180	HT29	viability (GeCKOv2 library)	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	1.17162050576843	[]	[]	5	hSpCas9	negative selection	4062698
137709749	137709772	5	-	26780180	HT29	viability (GeCKOv2 library)	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	1.4773923506865	[]	[]	7	hSpCas9	negative selection	4062699
137709751	137709774	5	+	26780180	HT29	viability (GeCKOv2 library)	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.972987289322867	[]	[]	4	hSpCas9	negative selection	4062700
137661913	137661936	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTTGGACTAGGTAGTCCCTAGG	KLHL3	ENSG00000146021	-0.10103230118690262	[4]	[2,2]	-2	hSpCas9	positive selection	4147395
137720484	137720507	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	-0.1313829350197503	[3]	[2,0]	-3	hSpCas9	positive selection	4147396
137720547	137720570	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCCCAGCCTGTATCAGAGTCTGG	KLHL3	ENSG00000146021	0.1557507405811636	[3]	[3,2]	4	hSpCas9	positive selection	4147397
137735632	137735655	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.1360344068712543	[3]	[1,2]	-3	hSpCas9	positive selection	4147398
137658220	137658243	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTAAAGACTTCCTCATTGAGG	KLHL3	ENSG00000146021	-0.47864258350347744	[3]	[1,0]	-8	hSpCas9	positive selection	4147399
137658126	137658149	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTACCTTGGGAAGGCTGACTGG	KLHL3	ENSG00000146021	-0.42435722001034903	[4]	[1,1]	-8	hSpCas9	positive selection	4147400
137720511	137720534	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTGACAGTGATCGTCCTCTGG	KLHL3	ENSG00000146021	-0.5282179168862869	[3]	[1,1]	-8	hSpCas9	positive selection	4147401
137661930	137661953	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCCGACTTCCTCTCTTACCTAGG	KLHL3	ENSG00000146021	0.35043114950194754	[4]	[5,2]	8	hSpCas9	positive selection	4147402
137709751	137709774	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.11709104127458897	[2]	[1,2]	3	hSpCas9	positive selection	4147404
137661913	137661936	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTTGGACTAGGTAGTCCCTAGG	KLHL3	ENSG00000146021	0.7070985316558154	[3]	[0,2,1,3]	4	hSpCas9	positive selection	4211417
137720484	137720507	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	-0.29306573130829516	[1]	[0,0,0,0]	-4	hSpCas9	positive selection	4211418
137720547	137720570	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCCCAGCCTGTATCAGAGTCTGG	KLHL3	ENSG00000146021	1.1199219484842375	[3]	[5,0,1,4]	8	hSpCas9	positive selection	4211419
137735632	137735655	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	0.030941805807724015	[3]	[3,0,1,0]	0	hSpCas9	positive selection	4211420
137658220	137658243	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTAAAGACTTCCTCATTGAGG	KLHL3	ENSG00000146021	-0.31174514097705797	[3]	[2,0,0,0]	-5	hSpCas9	positive selection	4211421
137658126	137658149	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTACCTTGGGAAGGCTGACTGG	KLHL3	ENSG00000146021	0.9076997162027601	[3]	[2,0,0,3]	6	hSpCas9	positive selection	4211422
137720511	137720534	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTGACAGTGATCGTCCTCTGG	KLHL3	ENSG00000146021	0.9566342529906783	[3]	[1,2,2,3]	6	hSpCas9	positive selection	4211423
137661930	137661953	5	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCCGACTTCCTCTCTTACCTAGG	KLHL3	ENSG00000146021	-0.07002848055637557	[4]	[3,0,2,0]	-1	hSpCas9	positive selection	4211424
137709751	137709774	5	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.37885598109169644	[3]	[2,0,0,0]	-5	hSpCas9	positive selection	4211426
137709792	137709815	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.3137320618599619	[2]	[2,0]	-6	hSpCas9	positive selection	4278852
137709751	137709774	5	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.4919926846538476	[1]	[0,1]	8	hSpCas9	positive selection	4278853
137720484	137720507	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	-0.31785034864300343	[3]	[3,0]	-6	hSpCas9	positive selection	4278854
137735632	137735655	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.18236254289730872	[2]	[2,0]	-4	hSpCas9	positive selection	4343108
137709749	137709772	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.4651683124077908	[2]	[1,0]	-7	hSpCas9	positive selection	4343109
137709825	137709848	5	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.2354483862575988	[3]	[2,3]	5	hSpCas9	positive selection	4343110
137639110	137639132	5	-	27760321	OCIAML3	viability	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	-0.07203679669930041	[717,603]	[462,524]	-1	hSpCas9	negative selection	4412676
137639900	137639922	5	-	27760321	OCIAML3	viability	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	-0.025131523362859565	[413,438]	[254,426]	0	hSpCas9	negative selection	4412677
137658178	137658200	5	+	27760321	OCIAML3	viability	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.9427340365696195	[255,221]	[317,410]	9	hSpCas9	negative selection	4412678
137661971	137661993	5	-	27760321	OCIAML3	viability	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.48083603874513337	[377,314]	[373,379]	6	hSpCas9	negative selection	4412679
137677601	137677623	5	-	27760321	OCIAML3	viability	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	0.3595252357049006	[679,699]	[681,712]	4	hSpCas9	negative selection	4412680
137639110	137639132	5	-	27760321	OCIAML2	viability	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	-0.35643949749957027	[717,603]	[403,431]	-4	hSpCas9	negative selection	4496139
137639900	137639922	5	-	27760321	OCIAML2	viability	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	0.016833230716241838	[413,438]	[300,416]	0	hSpCas9	negative selection	4496140
137658178	137658200	5	+	27760321	OCIAML2	viability	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	-0.29213264327187694	[255,221]	[84,252]	-4	hSpCas9	negative selection	4496141
137661971	137661993	5	-	27760321	OCIAML2	viability	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.07508022541838943	[377,314]	[328,247]	1	hSpCas9	negative selection	4496142
137677601	137677623	5	-	27760321	OCIAML2	viability	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.17827830782437876	[679,699]	[400,619]	-2	hSpCas9	negative selection	4496143
137639110	137639132	5	-	27760321	MV411	viability	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.9770670303529236	[717,603]	[1063,541]	7	hSpCas9	negative selection	4579602
137639900	137639922	5	-	27760321	MV411	viability	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	1.1555518989887605	[413,438]	[566,725]	8	hSpCas9	negative selection	4579603
137658178	137658200	5	+	27760321	MV411	viability	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.040061313373483065	[255,221]	[92,264]	0	hSpCas9	negative selection	4579604
137661971	137661993	5	-	27760321	MV411	viability	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.4612188247587937	[377,314]	[163,537]	3	hSpCas9	negative selection	4579605
137677601	137677623	5	-	27760321	MV411	viability	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	0.42464728611871183	[679,699]	[493,793]	3	hSpCas9	negative selection	4579606
137639110	137639132	5	-	27760321	HL60	viability	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.24794869725625035	[717,603]	[680,593]	3	hSpCas9	negative selection	4663065
137639900	137639922	5	-	27760321	HL60	viability	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	0.4848072347323104	[413,438]	[384,601]	6	hSpCas9	negative selection	4663066
137658178	137658200	5	+	27760321	HL60	viability	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.678292018412574	[255,221]	[265,359]	7	hSpCas9	negative selection	4663067
137661971	137661993	5	-	27760321	HL60	viability	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	-0.4581460146771781	[377,314]	[210,198]	-5	hSpCas9	negative selection	4663068
137677601	137677623	5	-	27760321	HL60	viability	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	0.2181802965131736	[679,699]	[661,654]	2	hSpCas9	negative selection	4663069
137639110	137639132	5	-	27760321	HT1080	viability	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.40088157903730914	[603,471]	[303,259]	2	hSpCas9	negative selection	4746528
137639900	137639922	5	-	27760321	HT1080	viability	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	0.2952805533426162	[438,342]	[225,152]	1	hSpCas9	negative selection	4746529
137658178	137658200	5	+	27760321	HT1080	viability	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	1.0087580732650023	[221,172]	[269,35]	5	hSpCas9	negative selection	4746530
137661971	137661993	5	-	27760321	HT1080	viability	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	-0.5583526544265831	[314,245]	[83,66]	-2	hSpCas9	negative selection	4746531
137677601	137677623	5	-	27760321	HT1080	viability	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	0.3465726737238122	[699,545]	[337,290]	1	hSpCas9	negative selection	4746532
137639110	137639132	5	-	27760321	HT29	viability after 7 days	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.13883837594240178	[603,471]	[734,940,608]	2	hSpCas9	negative selection	4829991
137639900	137639922	5	-	27760321	HT29	viability after 7 days	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	-0.2299984522944989	[438,342]	[412,500,370]	-3	hSpCas9	negative selection	4829992
137658178	137658200	5	+	27760321	HT29	viability after 7 days	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.44678833947412405	[221,172]	[388,313,340]	6	hSpCas9	negative selection	4829993
137661971	137661993	5	-	27760321	HT29	viability after 7 days	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.16757251092475092	[314,245]	[422,350,441]	2	hSpCas9	negative selection	4829994
137677601	137677623	5	-	27760321	HT29	viability after 7 days	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.6579393189570781	[699,545]	[357,639,502]	-7	hSpCas9	negative selection	4829995
137639110	137639132	5	-	27760321	HT29	viability after 25 days	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.42039649598320794	[603,471]	[888,684,896]	4	hSpCas9	negative selection	4913454
137639900	137639922	5	-	27760321	HT29	viability after 25 days	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	-0.18128479833481187	[438,342]	[331,464,387]	-2	hSpCas9	negative selection	4913455
137658178	137658200	5	+	27760321	HT29	viability after 25 days	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.5501772712729279	[221,172]	[405,224,357]	6	hSpCas9	negative selection	4913456
137661971	137661993	5	-	27760321	HT29	viability after 25 days	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.373105567940922	[314,245]	[587,282,356]	4	hSpCas9	negative selection	4913457
137677601	137677623	5	-	27760321	HT29	viability after 25 days	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.27896151990916107	[699,545]	[586,666,495]	-3	hSpCas9	negative selection	4913458
137639110	137639132	5	-	27760321	HT29	viability after 22 days	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.5182201278180983	[603,471]	[808,833,1032]	6	hSpCas9	negative selection	4996917
137639900	137639922	5	-	27760321	HT29	viability after 22 days	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	-0.07627921802163953	[438,342]	[272,430,587]	-1	hSpCas9	negative selection	4996918
137658178	137658200	5	+	27760321	HT29	viability after 22 days	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.3423558942641777	[221,172]	[284,234,348]	3	hSpCas9	negative selection	4996919
137661971	137661993	5	-	27760321	HT29	viability after 22 days	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.14931992346307255	[314,245]	[393,323,359]	1	hSpCas9	negative selection	4996920
137677601	137677623	5	-	27760321	HT29	viability after 22 days	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.37664922434610987	[699,545]	[835,422,395]	-4	hSpCas9	negative selection	4996921
137639110	137639132	5	-	27760321	HT29	viability after 19 days	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.2734820058185752	[603,471]	[1112,613,549]	2	hSpCas9	negative selection	5080380
137639900	137639922	5	-	27760321	HT29	viability after 19 days	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	0.27497101317630884	[438,342]	[446,380,775]	2	hSpCas9	negative selection	5080381
137658178	137658200	5	+	27760321	HT29	viability after 19 days	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.43064128979748606	[221,172]	[261,352,293]	4	hSpCas9	negative selection	5080382
137661971	137661993	5	-	27760321	HT29	viability after 19 days	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.11488487546650977	[314,245]	[517,171,368]	1	hSpCas9	negative selection	5080383
137677601	137677623	5	-	27760321	HT29	viability after 19 days	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.47422982967857963	[699,545]	[686,422,448]	-4	hSpCas9	negative selection	5080384
137639110	137639132	5	-	27760321	HT29	viability after 16 days	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.22271706189527252	[603,471]	[861,675,584]	2	hSpCas9	negative selection	5163843
137639900	137639922	5	-	27760321	HT29	viability after 16 days	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	-0.3242140676690681	[438,342]	[357,312,378]	-3	hSpCas9	negative selection	5163844
137658178	137658200	5	+	27760321	HT29	viability after 16 days	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.3678847113943774	[221,172]	[283,177,395]	4	hSpCas9	negative selection	5163845
137661971	137661993	5	-	27760321	HT29	viability after 16 days	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.0342390318068172	[314,245]	[219,301,432]	0	hSpCas9	negative selection	5163846
137677601	137677623	5	-	27760321	HT29	viability after 16 days	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.539195555806808	[699,545]	[542,510,389]	-5	hSpCas9	negative selection	5163847
137639110	137639132	5	-	27760321	HT29	viability after 13 days	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.2884480259219162	[603,471]	[657,864,763]	3	hSpCas9	negative selection	5247306
137639900	137639922	5	-	27760321	HT29	viability after 13 days	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	-0.0639994733087644	[438,342]	[513,411,378]	-1	hSpCas9	negative selection	5247307
137658178	137658200	5	+	27760321	HT29	viability after 13 days	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.16971287178968986	[221,172]	[323,175,271]	2	hSpCas9	negative selection	5247308
137661971	137661993	5	-	27760321	HT29	viability after 13 days	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	0.18942788195838545	[314,245]	[399,271,436]	2	hSpCas9	negative selection	5247309
137677601	137677623	5	-	27760321	HT29	viability after 13 days	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.20769031193263365	[699,545]	[366,868,640]	-2	hSpCas9	negative selection	5247310
137639110	137639132	5	-	27760321	HT29	viability after 10 days	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.3295679163611922	[603,471]	[1126,829,580]	4	hSpCas9	negative selection	5330769
137639900	137639922	5	-	27760321	HT29	viability after 10 days	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	-0.4856901527581486	[438,342]	[305,328,408]	-6	hSpCas9	negative selection	5330770
137658178	137658200	5	+	27760321	HT29	viability after 10 days	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.0004648021321471685	[221,172]	[214,322,204]	0	hSpCas9	negative selection	5330771
137661971	137661993	5	-	27760321	HT29	viability after 10 days	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	-0.14001231827304	[314,245]	[273,307,369]	-2	hSpCas9	negative selection	5330772
137677601	137677623	5	-	27760321	HT29	viability after 10 days	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	-0.45974293054191584	[699,545]	[726,380,582]	-5	hSpCas9	negative selection	5330773
137639110	137639132	5	-	27760321	MOLM13	viability	CCACGTGTATGCCGTGGGAGGG	KLHL3	ENSG00000146021	0.6771548001672147	[717,603]	[357,794]	5	hSpCas9	negative selection	5414232
137639900	137639922	5	-	27760321	MOLM13	viability	TGATTTCGAGGAGGACCGGTGG	KLHL3	ENSG00000146021	0.7606069098638363	[413,438]	[93,678]	5	hSpCas9	negative selection	5414233
137658178	137658200	5	+	27760321	MOLM13	viability	TCAATAGTCTCTGATCCAGAGG	KLHL3	ENSG00000146021	0.37798124340794215	[255,221]	[96,240]	2	hSpCas9	negative selection	5414234
137661971	137661993	5	-	27760321	MOLM13	viability	GAAACCCGTTTAGAGCACATGG	KLHL3	ENSG00000146021	-0.3113482700597403	[377,314]	[265,63]	-2	hSpCas9	negative selection	5414235
137677601	137677623	5	-	27760321	MOLM13	viability	GAATTTCTTAGCCTGAGTCTGG	KLHL3	ENSG00000146021	1.1330487547145258	[679,699]	[902,818]	7	hSpCas9	negative selection	5414236
137735640	137735663	5	-	27661255	K562	viability	GGCTGGGCCTCACACAATGGAGG	KLHL3	ENSG00000146021	0.3970418439222683	[603,928]	[879,731]	9	dCas9-KRAB	negative selection	5488957
137735802	137735825	5	-	27661255	K562	viability	GCTGCGAGTAAGTCAGAGGAAGG	KLHL3	ENSG00000146021	0.16643125193532238	[265,161]	[226,164]	6	dCas9-KRAB	negative selection	5488958
137709792	137709815	5	-	27260156	BXPC3	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.11237478033284554	[306]	[339,315,309,431]	2	hSpCas9	negative selection	5551312
137709751	137709774	5	+	27260156	BXPC3	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.8353427785856982	[80]	[127,163,164,147]	9	hSpCas9	negative selection	5551313
137720484	137720507	5	-	27260156	BXPC3	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.46538124433421496	[610]	[902,810,875,940]	8	hSpCas9	negative selection	5551314
137735632	137735655	5	-	27260156	BXPC3	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5315647212534762	[353]	[217,305,270,224]	-8	hSpCas9	negative selection	5615568
137709749	137709772	5	-	27260156	BXPC3	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.6291500902106106	[244]	[97,174,142,263]	-8	hSpCas9	negative selection	5615569
137709825	137709848	5	-	27260156	BXPC3	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.047082358875750074	[704]	[645,646,762,817]	-1	hSpCas9	negative selection	5615570
137709792	137709815	5	-	27260156	A673	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.17475395846432695	[306]	[394,415,432,416]	4	hSpCas9	negative selection	5672563
137709751	137709774	5	+	27260156	A673	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.39691164408799207	[80]	[133,126,148,100]	8	hSpCas9	negative selection	5672564
137720484	137720507	5	-	27260156	A673	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.3699128848877454	[610]	[1052,786,916,1055]	8	hSpCas9	negative selection	5672565
137735632	137735655	5	-	27260156	A673	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.4762085019225138	[353]	[261,403,236,311]	-8	hSpCas9	negative selection	5736819
137709749	137709772	5	-	27260156	A673	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.65381253181234	[244]	[126,290,138,180]	-9	hSpCas9	negative selection	5736820
137709825	137709848	5	-	27260156	A673	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.0034063349886048755	[704]	[1118,739,786,776]	0	hSpCas9	negative selection	5736821
137709792	137709815	5	-	27260156	A375	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.24614918004994185	[306]	[326,648,329,423]	3	hSpCas9	negative selection	5793814
137709751	137709774	5	+	27260156	A375	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.1497425587039194	[80]	[178,103,88,53]	2	hSpCas9	negative selection	5793815
137720484	137720507	5	-	27260156	A375	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.6598000920414611	[610]	[1189,1297,917,1123]	8	hSpCas9	negative selection	5793816
137735632	137735655	5	-	27260156	A375	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.021371229593245278	[353]	[259,419,599,354]	0	hSpCas9	negative selection	5858070
137709749	137709772	5	-	27260156	A375	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.6995704593564747	[244]	[174,211,181,143]	-7	hSpCas9	negative selection	5858071
137709825	137709848	5	-	27260156	A375	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.03188371598873929	[704]	[717,1097,769,686]	0	hSpCas9	negative selection	5858072
137709792	137709815	5	-	27260156	COLO741	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.18427865136360844	[306]	[310,388,332]	-4	hSpCas9	negative selection	5915065
137709751	137709774	5	+	27260156	COLO741	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.3804273269678933	[80]	[126,45,69]	-7	hSpCas9	negative selection	5915066
137720484	137720507	5	-	27260156	COLO741	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.2883211150107616	[610]	[1061,1032,784]	6	hSpCas9	negative selection	5915067
137735632	137735655	5	-	27260156	COLO741	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.27946011710443003	[353]	[432,467,231]	-5	hSpCas9	negative selection	5979321
137709749	137709772	5	-	27260156	COLO741	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.05753998821595929	[244]	[257,308,328]	-1	hSpCas9	negative selection	5979322
137709825	137709848	5	-	27260156	COLO741	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.04205042881169063	[704]	[1193,983,645]	0	hSpCas9	negative selection	5979323
137709792	137709815	5	-	27260156	CAL120	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.0918160741932822	[306]	[366,318,526]	1	hSpCas9	negative selection	6036316
137709751	137709774	5	+	27260156	CAL120	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.781374901314932	[80]	[268,143,121]	9	hSpCas9	negative selection	6036317
137720484	137720507	5	-	27260156	CAL120	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.528282313923006	[610]	[1243,1397,676]	7	hSpCas9	negative selection	6036318
137735632	137735655	5	-	27260156	CAL120	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5936073751821176	[353]	[298,413,165]	-7	hSpCas9	negative selection	6100572
137709749	137709772	5	-	27260156	CAL120	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.18928940826962481	[244]	[263,239,296]	-3	hSpCas9	negative selection	6100573
137709825	137709848	5	-	27260156	CAL120	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.04336954845601004	[704]	[677,770,1222]	0	hSpCas9	negative selection	6100574
137709792	137709815	5	-	27260156	CADOES1	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.2149830761778252	[306]	[514,270,234,302]	3	hSpCas9	negative selection	6157567
137709751	137709774	5	+	27260156	CADOES1	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.42275953988052306	[80]	[45,177,110,67]	7	hSpCas9	negative selection	6157568
137720484	137720507	5	-	27260156	CADOES1	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.39135898532776364	[610]	[640,613,938,788]	6	hSpCas9	negative selection	6157569
137735632	137735655	5	-	27260156	CADOES1	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.6572282539865824	[353]	[207,133,128,369]	-8	hSpCas9	negative selection	6221823
137709749	137709772	5	-	27260156	CADOES1	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.47103038727623825	[244]	[224,131,144,154]	-7	hSpCas9	negative selection	6221824
137709825	137709848	5	-	27260156	CADOES1	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.06807330550768198	[704]	[679,471,705,898]	1	hSpCas9	negative selection	6221825
137709792	137709815	5	-	27260156	EWS502	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.5117974863109209	[306]	[178,163,295,285]	-7	hSpCas9	negative selection	6278818
137709751	137709774	5	+	27260156	EWS502	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.2688397269368843	[80]	[47,115,183,69]	5	hSpCas9	negative selection	6278819
137720484	137720507	5	-	27260156	EWS502	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.49594261950091584	[610]	[758,908,818,1197]	8	hSpCas9	negative selection	6278820
137735632	137735655	5	-	27260156	EWS502	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.4146399437202782	[353]	[218,298,309,304]	-6	hSpCas9	negative selection	6343074
137709749	137709772	5	-	27260156	EWS502	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.43960316201369865	[244]	[233,141,233,148]	-6	hSpCas9	negative selection	6343075
137709825	137709848	5	-	27260156	EWS502	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.056277024696114064	[704]	[690,790,724,658]	-1	hSpCas9	negative selection	6343076
137709792	137709815	5	-	27260156	EW8	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.24507707911872811	[306]	[215,260,174,193]	-4	hSpCas9	negative selection	6400069
137709751	137709774	5	+	27260156	EW8	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.27260127432849623	[80]	[50,68,41,56]	-5	hSpCas9	negative selection	6400070
137720484	137720507	5	-	27260156	EW8	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.27152655618918947	[610]	[868,685,383,516]	5	hSpCas9	negative selection	6400071
137735632	137735655	5	-	27260156	EW8	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.2888889129770383	[353]	[245,210,214,270]	-5	hSpCas9	negative selection	6464325
137709749	137709772	5	-	27260156	EW8	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.3727061928146733	[244]	[148,151,185,119]	-6	hSpCas9	negative selection	6464326
137709825	137709848	5	-	27260156	EW8	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.12436634490991222	[704]	[456,606,386,659]	-2	hSpCas9	negative selection	6464327
137709792	137709815	5	-	27260156	CORL105	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.1772327523112846	[306]	[398,342,555,351]	3	hSpCas9	negative selection	6521320
137709751	137709774	5	+	27260156	CORL105	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.333751563118458	[80]	[177,131,87,76]	6	hSpCas9	negative selection	6521321
137720484	137720507	5	-	27260156	CORL105	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.404232498698243	[610]	[989,932,921,938]	7	hSpCas9	negative selection	6521322
137735632	137735655	5	-	27260156	CORL105	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.8581261520894123	[353]	[167,172,303,279]	-9	hSpCas9	negative selection	6585576
137709749	137709772	5	-	27260156	CORL105	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.4065371657710575	[244]	[240,266,174,175]	-6	hSpCas9	negative selection	6585577
137709825	137709848	5	-	27260156	CORL105	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.014516163981299623	[704]	[676,838,1077,709]	0	hSpCas9	negative selection	6585578
137709792	137709815	5	-	27260156	HS294T	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.08341209038201736	[306]	[100,147,135,117]	1	hSpCas9	negative selection	6642571
137709751	137709774	5	+	27260156	HS294T	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.08186928992037279	[80]	[21,14,29,73]	1	hSpCas9	negative selection	6642572
137720484	137720507	5	-	27260156	HS294T	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.29515968086452266	[610]	[388,208,261,291]	4	hSpCas9	negative selection	6642573
137735632	137735655	5	-	27260156	HS294T	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.18391600311119366	[353]	[125,171,86,88]	-3	hSpCas9	negative selection	6706827
137709749	137709772	5	-	27260156	HS294T	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.4989848861752777	[244]	[102,53,49,55]	-6	hSpCas9	negative selection	6706828
137709825	137709848	5	-	27260156	HS294T	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.09493690553233625	[704]	[246,220,248,314]	-1	hSpCas9	negative selection	6706829
137709792	137709815	5	-	27260156	HCC44	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.32129544696525625	[306]	[177,298,382,255]	-5	hSpCas9	negative selection	6763822
137709751	137709774	5	+	27260156	HCC44	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.0009726318756730912	[80]	[124,85,60,91]	0	hSpCas9	negative selection	6763823
137720484	137720507	5	-	27260156	HCC44	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.49813350643702875	[610]	[998,812,1024,1088]	7	hSpCas9	negative selection	6763824
137735632	137735655	5	-	27260156	HCC44	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.4814547318603876	[353]	[352,151,401,282]	-6	hSpCas9	negative selection	6828078
137709749	137709772	5	-	27260156	HCC44	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.05835834184077304	[244]	[138,268,287,354]	-1	hSpCas9	negative selection	6828079
137709825	137709848	5	-	27260156	HCC44	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.15840118775008116	[704]	[806,902,1235,663]	2	hSpCas9	negative selection	6828080
137709792	137709815	5	-	27260156	G402	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.0685453758566511	[306]	[297,540,410,187]	-1	hSpCas9	negative selection	6885073
137709751	137709774	5	+	27260156	G402	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.20465777451067568	[80]	[19,64,181,65]	-3	hSpCas9	negative selection	6885074
137720484	137720507	5	-	27260156	G402	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.3895822294113928	[610]	[1592,896,620,880]	5	hSpCas9	negative selection	6885075
137735632	137735655	5	-	27260156	G402	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.18263175566444162	[353]	[889,239,408,62]	-2	hSpCas9	negative selection	6949329
137709749	137709772	5	-	27260156	G402	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.34867900160349863	[244]	[261,387,235,72]	-4	hSpCas9	negative selection	6949330
137709825	137709848	5	-	27260156	G402	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.3525056234060042	[704]	[1289,921,809,1370]	4	hSpCas9	negative selection	6949331
137709792	137709815	5	-	27260156	L33	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.33336870438283045	[306]	[437,121,274,372]	7	hSpCas9	negative selection	7006324
137709751	137709774	5	+	27260156	L33	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.3870194612260027	[80]	[140,28,58,116]	7	hSpCas9	negative selection	7006325
137720484	137720507	5	-	27260156	L33	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.21994385727717763	[610]	[691,330,433,656]	5	hSpCas9	negative selection	7006326
137735632	137735655	5	-	27260156	L33	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.41451216474558333	[353]	[263,138,117,270]	-7	hSpCas9	negative selection	7070580
137709749	137709772	5	-	27260156	L33	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.6055934890449477	[244]	[174,71,108,119]	-8	hSpCas9	negative selection	7070581
137709825	137709848	5	-	27260156	L33	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.015810670711341124	[704]	[600,282,525,663]	0	hSpCas9	negative selection	7070582
137709792	137709815	5	-	27260156	K562	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.8460829177240587	[306]	[253,129,59,166]	-7	hSpCas9	negative selection	7127575
137709751	137709774	5	+	27260156	K562	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.8247367450890972	[80]	[45,10,62,40]	-7	hSpCas9	negative selection	7127576
137720484	137720507	5	-	27260156	K562	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.8604304339786693	[610]	[1441,751,819,948]	9	hSpCas9	negative selection	7127577
137735632	137735655	5	-	27260156	K562	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.3180114171617225	[353]	[426,354,108,147]	-4	hSpCas9	negative selection	7191831
137709749	137709772	5	-	27260156	K562	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	0.07195180919298516	[244]	[267,320,138,196]	0	hSpCas9	negative selection	7191832
137709825	137709848	5	-	27260156	K562	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.6721513605261581	[704]	[1053,1130,1028,803]	8	hSpCas9	negative selection	7191833
137709792	137709815	5	-	27260156	HT29	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.3295752318058179	[306]	[568,639,388,315]	6	hSpCas9	negative selection	7248826
137709751	137709774	5	+	27260156	HT29	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.21185511279112745	[80]	[73,93,91,79]	-4	hSpCas9	negative selection	7248827
137720484	137720507	5	-	27260156	HT29	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.47188165379798946	[610]	[1109,1082,903,1026]	8	hSpCas9	negative selection	7248828
137735632	137735655	5	-	27260156	HT29	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5855389270088593	[353]	[315,292,289,252]	-7	hSpCas9	negative selection	7313082
137709749	137709772	5	-	27260156	HT29	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.3697666292538515	[244]	[195,303,220,205]	-6	hSpCas9	negative selection	7313083
137709825	137709848	5	-	27260156	HT29	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.035455120878214896	[704]	[1001,775,926,662]	0	hSpCas9	negative selection	7313084
137709792	137709815	5	-	27260156	MHHES1	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.3643108943220327	[306]	[399,298,203,199]	-6	hSpCas9	negative selection	7370077
137709751	137709774	5	+	27260156	MHHES1	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.4590613339014147	[80]	[142,227,41,102]	7	hSpCas9	negative selection	7370078
137720484	137720507	5	-	27260156	MHHES1	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.3779810323052964	[610]	[1202,1310,595,594]	6	hSpCas9	negative selection	7370079
137735632	137735655	5	-	27260156	MHHES1	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.4622160889438662	[353]	[362,186,428,193]	-7	hSpCas9	negative selection	7434333
137709749	137709772	5	-	27260156	MHHES1	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.1996742319923872	[244]	[295,296,152,224]	-4	hSpCas9	negative selection	7434334
137709825	137709848	5	-	27260156	MHHES1	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.04947546641324341	[704]	[1069,893,653,711]	0	hSpCas9	negative selection	7434335
137709792	137709815	5	-	27260156	MEWO	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.15483616508228432	[306]	[322,284,351]	3	hSpCas9	negative selection	7491328
137709751	137709774	5	+	27260156	MEWO	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.4081794204021625	[80]	[44,48,74]	-7	hSpCas9	negative selection	7491329
137720484	137720507	5	-	27260156	MEWO	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.1337434738326551	[610]	[726,558,614]	3	hSpCas9	negative selection	7491330
137735632	137735655	5	-	27260156	MEWO	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.735335070707694	[353]	[234,148,219]	-9	hSpCas9	negative selection	7555584
137709749	137709772	5	-	27260156	MEWO	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.3112457595080831	[244]	[218,142,198]	-6	hSpCas9	negative selection	7555585
137709825	137709848	5	-	27260156	MEWO	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.22364611696300407	[704]	[769,831,707]	5	hSpCas9	negative selection	7555586
137709792	137709815	5	-	27260156	LNCAPCLONEFGC	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.2663687066777366	[306]	[326,306,376,334]	4	hSpCas9	negative selection	7612579
137709751	137709774	5	+	27260156	LNCAPCLONEFGC	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.010803698245837712	[80]	[72,94,80,41]	0	hSpCas9	negative selection	7612580
137720484	137720507	5	-	27260156	LNCAPCLONEFGC	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.5121307628397485	[610]	[795,861,789,703]	7	hSpCas9	negative selection	7612581
137735632	137735655	5	-	27260156	LNCAPCLONEFGC	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.31477725444814036	[353]	[350,170,277,237]	-5	hSpCas9	negative selection	7676835
137709749	137709772	5	-	27260156	LNCAPCLONEFGC	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.33236038596283723	[244]	[146,181,208,171]	-5	hSpCas9	negative selection	7676836
137709825	137709848	5	-	27260156	LNCAPCLONEFGC	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.08371830538948888	[704]	[754,524,843,615]	1	hSpCas9	negative selection	7676837
137709792	137709815	5	-	27260156	PANC0327	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.5171713063230869	[306]	[309,474,587,170]	7	hSpCas9	negative selection	7733830
137709751	137709774	5	+	27260156	PANC0327	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.5321442550620286	[80]	[61,19,323,17]	7	hSpCas9	negative selection	7733831
137720484	137720507	5	-	27260156	PANC0327	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.3820092629548392	[610]	[701,771,610,734]	5	hSpCas9	negative selection	7733832
137735632	137735655	5	-	27260156	PANC0327	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	0.07667870351967337	[353]	[368,196,427,352]	1	hSpCas9	negative selection	7798086
137709749	137709772	5	-	27260156	PANC0327	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	0.1073633489791449	[244]	[253,128,286,282]	1	hSpCas9	negative selection	7798087
137709825	137709848	5	-	27260156	PANC0327	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.5143049346808661	[704]	[520,332,409,509]	-6	hSpCas9	negative selection	7798088
137709792	137709815	5	-	27260156	NCIH2009	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.29421855311985134	[306]	[677,527,400]	4	hSpCas9	negative selection	7855081
137709751	137709774	5	+	27260156	NCIH2009	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.5569142787099071	[80]	[273,189,55]	7	hSpCas9	negative selection	7855082
137720484	137720507	5	-	27260156	NCIH2009	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.5397864676129989	[610]	[1408,1028,1319]	7	hSpCas9	negative selection	7855083
137735632	137735655	5	-	27260156	NCIH2009	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.3226918685544749	[353]	[465,321,412]	-4	hSpCas9	negative selection	7919337
137709749	137709772	5	-	27260156	NCIH2009	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.33319382763209604	[244]	[309,174,338]	-4	hSpCas9	negative selection	7919338
137709825	137709848	5	-	27260156	NCIH2009	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.1401470278582017	[704]	[1175,931,626]	-2	hSpCas9	negative selection	7919339
137709792	137709815	5	-	27260156	NCIH1373	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.40470475101755377	[306]	[591,302,287,181]	4	hSpCas9	negative selection	7976332
137709751	137709774	5	+	27260156	NCIH1373	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-1.0439554434274214	[80]	[58,60,28,6]	-8	hSpCas9	negative selection	7976333
137720484	137720507	5	-	27260156	NCIH1373	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.6137202088527651	[610]	[1547,989,535,319]	6	hSpCas9	negative selection	7976334
137735632	137735655	5	-	27260156	NCIH1373	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.16729770424481677	[353]	[642,259,212,92]	-2	hSpCas9	negative selection	8040588
137709749	137709772	5	-	27260156	NCIH1373	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.9478530520545585	[244]	[207,149,132,21]	-7	hSpCas9	negative selection	8040589
137709825	137709848	5	-	27260156	NCIH1373	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.7274241627624796	[704]	[679,354,451,121]	-6	hSpCas9	negative selection	8040590
137709792	137709815	5	-	27260156	PATU8902	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.2437848418626588	[306]	[442,721,446,414]	2	hSpCas9	negative selection	8097583
137709751	137709774	5	+	27260156	PATU8902	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-1.1459375109814882	[80]	[4,77,82,26]	-7	hSpCas9	negative selection	8097584
137720484	137720507	5	-	27260156	PATU8902	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.004340685194306748	[610]	[544,925,999,908]	0	hSpCas9	negative selection	8097585
137735632	137735655	5	-	27260156	PATU8902	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5404905135144167	[353]	[228,229,305,632]	-5	hSpCas9	negative selection	8161839
137709749	137709772	5	-	27260156	PATU8902	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-1.830957275792337	[244]	[280,23,40,41]	-9	hSpCas9	negative selection	8161840
137709825	137709848	5	-	27260156	PATU8902	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.05526324358209944	[704]	[1018,775,634,1485]	0	hSpCas9	negative selection	8161841
137709792	137709815	5	-	27260156	PANC1	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.42777120014959646	[306]	[303,577,375,223]	7	hSpCas9	negative selection	8218834
137709751	137709774	5	+	27260156	PANC1	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.07037112451080807	[80]	[44,122,68,65]	1	hSpCas9	negative selection	8218835
137720484	137720507	5	-	27260156	PANC1	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.3010389587584284	[610]	[642,743,648,571]	5	hSpCas9	negative selection	8218836
137735632	137735655	5	-	27260156	PANC1	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5610936843622711	[353]	[202,291,202,149]	-7	hSpCas9	negative selection	8283090
137709749	137709772	5	-	27260156	PANC1	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.17042955769174206	[244]	[184,180,278,111]	-3	hSpCas9	negative selection	8283091
137709825	137709848	5	-	27260156	PANC1	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.0951488343163428	[704]	[650,781,562,612]	1	hSpCas9	negative selection	8283092
137709792	137709815	5	-	27260156	PANC0813	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.3395626935582247	[306]	[464,362,596,403]	5	hSpCas9	negative selection	8340085
137709751	137709774	5	+	27260156	PANC0813	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.5258648501135479	[80]	[165,46,255,84]	8	hSpCas9	negative selection	8340086
137720484	137720507	5	-	27260156	PANC0813	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.4833962653524477	[610]	[972,955,949,1122]	7	hSpCas9	negative selection	8340087
137735632	137735655	5	-	27260156	PANC0813	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5455740440126222	[353]	[316,224,379,223]	-7	hSpCas9	negative selection	8404341
137709749	137709772	5	-	27260156	PANC0813	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.3796286287276196	[244]	[242,257,246,142]	-5	hSpCas9	negative selection	8404342
137709825	137709848	5	-	27260156	PANC0813	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.21557832016545608	[704]	[1046,1255,694,858]	3	hSpCas9	negative selection	8404343
137709792	137709815	5	-	27260156	RDES	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.18478380083355483	[306]	[276,232,388,358]	-3	hSpCas9	negative selection	8461336
137709751	137709774	5	+	27260156	RDES	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.0949926369720071	[80]	[55,119,148,75]	1	hSpCas9	negative selection	8461337
137720484	137720507	5	-	27260156	RDES	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.16889284607421134	[610]	[708,703,998,749]	2	hSpCas9	negative selection	8461338
137735632	137735655	5	-	27260156	RDES	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.4655094283097016	[353]	[195,276,223,530]	-7	hSpCas9	negative selection	8525592
137709749	137709772	5	-	27260156	RDES	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.4677366004081067	[244]	[143,207,158,327]	-7	hSpCas9	negative selection	8525593
137709825	137709848	5	-	27260156	RDES	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.01355591138796608	[704]	[649,801,867,995]	0	hSpCas9	negative selection	8525594
137709792	137709815	5	-	27260156	PC3	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.13833673621328968	[306]	[177,412,612,284]	3	hSpCas9	negative selection	8582587
137709751	137709774	5	+	27260156	PC3	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.29516545095731894	[80]	[70,80,74,23]	-6	hSpCas9	negative selection	8582588
137720484	137720507	5	-	27260156	PC3	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.2122263234289909	[610]	[615,706,1220,411]	5	hSpCas9	negative selection	8582589
137735632	137735655	5	-	27260156	PC3	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.1821711925303346	[353]	[325,239,428,240]	-4	hSpCas9	negative selection	8646843
137709749	137709772	5	-	27260156	PC3	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.010675817563572942	[244]	[147,240,338,299]	0	hSpCas9	negative selection	8646844
137709825	137709848	5	-	27260156	PC3	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.02246414921676887	[704]	[553,988,931,325]	0	hSpCas9	negative selection	8646845
137709792	137709815	5	-	27260156	PATU8988T	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.33067593383577554	[306]	[381,349,334,427]	5	hSpCas9	negative selection	8703838
137709751	137709774	5	+	27260156	PATU8988T	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.536746616109532	[80]	[85,130,101,138]	8	hSpCas9	negative selection	8703839
137720484	137720507	5	-	27260156	PATU8988T	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.7000525198204433	[610]	[871,919,865,1194]	9	hSpCas9	negative selection	8703840
137735632	137735655	5	-	27260156	PATU8988T	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.6288630427222055	[353]	[226,302,225,128]	-7	hSpCas9	negative selection	8768094
137709749	137709772	5	-	27260156	PATU8988T	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.8499157311113612	[244]	[158,143,122,97]	-8	hSpCas9	negative selection	8768095
137709825	137709848	5	-	27260156	PATU8988T	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.27007914238624287	[704]	[848,1041,719,685]	4	hSpCas9	negative selection	8768096
137709792	137709815	5	-	27260156	T47D	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.07260661994699436	[306]	[386,367,375,373]	1	hSpCas9	negative selection	8825089
137709751	137709774	5	+	27260156	T47D	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.2487149226066565	[80]	[109,96,98,144]	5	hSpCas9	negative selection	8825090
137720484	137720507	5	-	27260156	T47D	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.38869187453195436	[610]	[831,848,897,1162]	7	hSpCas9	negative selection	8825091
137735632	137735655	5	-	27260156	T47D	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.47525979409419966	[353]	[266,246,407,265]	-7	hSpCas9	negative selection	8889345
137709749	137709772	5	-	27260156	T47D	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.24492876720047274	[244]	[330,192,192,251]	-5	hSpCas9	negative selection	8889346
137709825	137709848	5	-	27260156	T47D	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.38185204365407277	[704]	[957,739,1682,912]	7	hSpCas9	negative selection	8889347
137709792	137709815	5	-	27260156	SU8686	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.46100965408100203	[306]	[384,312,545,455]	7	hSpCas9	negative selection	8946340
137709751	137709774	5	+	27260156	SU8686	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.34416051481695664	[80]	[36,78,153,157]	6	hSpCas9	negative selection	8946341
137720484	137720507	5	-	27260156	SU8686	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.3635246755221733	[610]	[647,640,743,1174]	6	hSpCas9	negative selection	8946342
137735632	137735655	5	-	27260156	SU8686	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.6729452080759943	[353]	[185,263,216,207]	-7	hSpCas9	negative selection	9010596
137709749	137709772	5	-	27260156	SU8686	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.9377314265426646	[244]	[127,136,139,94]	-8	hSpCas9	negative selection	9010597
137709825	137709848	5	-	27260156	SU8686	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.10291037701077099	[704]	[820,544,703,981]	1	hSpCas9	negative selection	9010598
137709792	137709815	5	-	27260156	SKES1	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.34292175120376245	[306]	[288,264,234,189]	-6	hSpCas9	negative selection	9067591
137709751	137709774	5	+	27260156	SKES1	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	0.010313605293894135	[80]	[90,77,109,49]	0	hSpCas9	negative selection	9067592
137720484	137720507	5	-	27260156	SKES1	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.21523293836288165	[610]	[741,898,647,577]	4	hSpCas9	negative selection	9067593
137735632	137735655	5	-	27260156	SKES1	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.38962559115388334	[353]	[462,233,239,172]	-7	hSpCas9	negative selection	9131847
137709749	137709772	5	-	27260156	SKES1	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.08126725143698188	[244]	[225,259,262,180]	-2	hSpCas9	negative selection	9131848
137709825	137709848	5	-	27260156	SKES1	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.05443114347409239	[704]	[821,768,564,588]	-1	hSpCas9	negative selection	9131849
137709792	137709815	5	-	27260156	TOV112D	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.3408670316265229	[306]	[233,248,191,294]	-6	hSpCas9	negative selection	9188842
137709751	137709774	5	+	27260156	TOV112D	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.08359252169771958	[80]	[137,40,63,59]	-2	hSpCas9	negative selection	9188843
137720484	137720507	5	-	27260156	TOV112D	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.34260043233781684	[610]	[786,849,898,590]	6	hSpCas9	negative selection	9188844
137735632	137735655	5	-	27260156	TOV112D	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.2610998125220804	[353]	[232,570,277,166]	-5	hSpCas9	negative selection	9253098
137709749	137709772	5	-	27260156	TOV112D	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.4724603708773216	[244]	[150,288,95,195]	-7	hSpCas9	negative selection	9253099
137709825	137709848	5	-	27260156	TOV112D	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.08054011149139684	[704]	[708,527,751,933]	1	hSpCas9	negative selection	9253100
137709792	137709815	5	-	27260156	TC71	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	0.015425487171041419	[306]	[276,367,293,397]	0	hSpCas9	negative selection	9310093
137709751	137709774	5	+	27260156	TC71	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.0485726623066598	[80]	[103,51,84,94]	-1	hSpCas9	negative selection	9310094
137720484	137720507	5	-	27260156	TC71	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.36033108814375353	[610]	[829,901,780,852]	8	hSpCas9	negative selection	9310095
137735632	137735655	5	-	27260156	TC71	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5670094192357795	[353]	[271,216,292,239]	-9	hSpCas9	negative selection	9374349
137709749	137709772	5	-	27260156	TC71	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	0.007406212380339783	[244]	[361,348,159,180]	0	hSpCas9	negative selection	9374350
137709825	137709848	5	-	27260156	TC71	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	0.10565339653515926	[704]	[776,840,801,834]	2	hSpCas9	negative selection	9374351
137709792	137709815	5	-	27260156	TC32	viability	CGAGATAGAAGCCCACCGTGTGG	KLHL3	ENSG00000146021	-0.14416415537869343	[306]	[314,133,289,340]	-3	hSpCas9	negative selection	9431344
137709751	137709774	5	+	27260156	TC32	viability	TGTGAACATCGCACAGAAGTAGG	KLHL3	ENSG00000146021	-0.14422130443550962	[80]	[69,41,72,98]	-3	hSpCas9	negative selection	9431345
137720484	137720507	5	-	27260156	TC32	viability	CCACATGGGGAAAGCATTCAAGG	KLHL3	ENSG00000146021	0.308160716065118	[610]	[574,552,1018,789]	5	hSpCas9	negative selection	9431346
137735632	137735655	5	-	27260156	TC32	viability	CTCACACAATGGAGGGTGAAAGG	KLHL3	ENSG00000146021	-0.5192990004402116	[353]	[233,166,309,241]	-7	hSpCas9	negative selection	9495600
137709749	137709772	5	-	27260156	TC32	viability	TACTTCTGTGCGATGTTCACAGG	KLHL3	ENSG00000146021	-0.4057197260056806	[244]	[163,129,227,190]	-6	hSpCas9	negative selection	9495601
137709825	137709848	5	-	27260156	TC32	viability	GTTGTGTGACGTGATGATTGTGG	KLHL3	ENSG00000146021	-0.2251251842629196	[704]	[520,373,842,626]	-4	hSpCas9	negative selection	9495602
137658130	137658153	5	-	27869803	HPAFII	viability after 27 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.4965756895140634	[100]	[5,63,NaN]	-4	hSpCas9	negative selection	9590074
137661922	137661945	5	+	27869803	HPAFII	viability after 27 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.28562797506971793	[283]	[151,206,NaN]	2	hSpCas9	negative selection	9590075
137677595	137677618	5	-	27869803	HPAFII	viability after 27 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.3049275181359105	[207]	[241,45,NaN]	2	hSpCas9	negative selection	9590076
137692284	137692307	5	-	27869803	HPAFII	viability after 27 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.1563102241010615	[235]	[170,110,NaN]	1	hSpCas9	negative selection	9590077
137709780	137709803	5	+	27869803	HPAFII	viability after 27 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.3325999544029373	[605]	[234,267,NaN]	-2	hSpCas9	negative selection	9590078
137720464	137720487	5	-	27869803	HPAFII	viability after 27 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.06541823191117549	[213]	[132,104,NaN]	0	hSpCas9	negative selection	9590079
137658130	137658153	5	-	27869803	HPAFII	viability after 15 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.6436114930931089	[100]	[58,75,NaN]	-6	hSpCas9	negative selection	9672523
137661922	137661945	5	+	27869803	HPAFII	viability after 15 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.5523812682131621	[283]	[565,373,NaN]	6	hSpCas9	negative selection	9672524
137677595	137677618	5	-	27869803	HPAFII	viability after 15 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-0.6923844085800599	[207]	[162,122,NaN]	-6	hSpCas9	negative selection	9672525
137692284	137692307	5	-	27869803	HPAFII	viability after 15 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.5426048542352894	[235]	[302,93,NaN]	-5	hSpCas9	negative selection	9672526
137709780	137709803	5	+	27869803	HPAFII	viability after 15 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.39337341427338046	[605]	[374,570,NaN]	-4	hSpCas9	negative selection	9672527
137720464	137720487	5	-	27869803	HPAFII	viability after 15 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.1806079883608788	[213]	[235,275,NaN]	2	hSpCas9	negative selection	9672528
137658130	137658153	5	-	27869803	ASPC1	viability after 36 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.7432763325976746	[318]	[0,195,8]	-6	hSpCas9	negative selection	9754972
137661922	137661945	5	+	27869803	ASPC1	viability after 36 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.4177233433420411	[873]	[83,292,275]	-4	hSpCas9	negative selection	9754973
137677595	137677618	5	-	27869803	ASPC1	viability after 36 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-2.209885663554082	[655]	[45,44,54]	-9	hSpCas9	negative selection	9754974
137692284	137692307	5	-	27869803	ASPC1	viability after 36 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.08322924824597303	[710]	[191,185,370]	0	hSpCas9	negative selection	9754975
137709780	137709803	5	+	27869803	ASPC1	viability after 36 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.008852977345140456	[1266]	[609,497,268]	0	hSpCas9	negative selection	9754976
137720464	137720487	5	-	27869803	ASPC1	viability after 36 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	-0.2755051033934714	[497]	[125,181,123]	-3	hSpCas9	negative selection	9754977
137658130	137658153	5	-	27869803	PATU8988S	viability after 35 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.1309088381803596	[252]	[117,67,NaN]	-1	hSpCas9	negative selection	9837421
137661922	137661945	5	+	27869803	PATU8988S	viability after 35 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.13520973918528006	[776]	[258,310,NaN]	-1	hSpCas9	negative selection	9837422
137677595	137677618	5	-	27869803	PATU8988S	viability after 35 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-0.5660301434382655	[398]	[128,87,NaN]	-5	hSpCas9	negative selection	9837423
137692284	137692307	5	-	27869803	PATU8988S	viability after 35 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.38551909746047197	[478]	[257,245,NaN]	4	hSpCas9	negative selection	9837424
137709780	137709803	5	+	27869803	PATU8988S	viability after 35 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.03408758650732624	[1378]	[508,575,NaN]	0	hSpCas9	negative selection	9837425
137720464	137720487	5	-	27869803	PATU8988S	viability after 35 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.9506662206011374	[380]	[330,261,NaN]	8	hSpCas9	negative selection	9837426
137658130	137658153	5	-	27869803	PATU8988S	viability after 31 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.3498498190791086	[252]	[72,86,NaN]	-4	hSpCas9	negative selection	9919870
137661922	137661945	5	+	27869803	PATU8988S	viability after 31 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	-0.3295744521905536	[776]	[191,315,NaN]	-4	hSpCas9	negative selection	9919871
137677595	137677618	5	-	27869803	PATU8988S	viability after 31 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	-0.8815909623259266	[398]	[55,124,NaN]	-7	hSpCas9	negative selection	9919872
137692284	137692307	5	-	27869803	PATU8988S	viability after 31 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.7101773320823886	[478]	[282,349,NaN]	8	hSpCas9	negative selection	9919873
137709780	137709803	5	+	27869803	PATU8988S	viability after 31 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.09903447392838127	[1378]	[453,588,NaN]	-1	hSpCas9	negative selection	9919874
137720464	137720487	5	-	27869803	PATU8988S	viability after 31 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	1.0990573236197592	[380]	[313,339,NaN]	9	hSpCas9	negative selection	9919875
137658130	137658153	5	-	27869803	HPAFII	viability after 35 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-1.2367888804748717	[100]	[0,44,NaN]	-6	hSpCas9	negative selection	10002319
137661922	137661945	5	+	27869803	HPAFII	viability after 35 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.08704331768781912	[283]	[171,130,NaN]	0	hSpCas9	negative selection	10002320
137677595	137677618	5	-	27869803	HPAFII	viability after 35 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.101323076078634	[207]	[151,68,NaN]	0	hSpCas9	negative selection	10002321
137692284	137692307	5	-	27869803	HPAFII	viability after 35 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	0.3611502331025494	[235]	[128,180,NaN]	2	hSpCas9	negative selection	10002322
137709780	137709803	5	+	27869803	HPAFII	viability after 35 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.15185868101632782	[605]	[190,371,NaN]	-1	hSpCas9	negative selection	10002323
137720464	137720487	5	-	27869803	HPAFII	viability after 35 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.11929651251480511	[213]	[175,51,NaN]	0	hSpCas9	negative selection	10002324
137658130	137658153	5	-	27869803	HPAFII	viability after 31 days	GACTCCAGTCAGCCTTCCCAAGG	KLHL3	ENSG00000146021	-0.25737306349933564	[100]	[0,97,NaN]	-2	hSpCas9	negative selection	10084768
137661922	137661945	5	+	27869803	HPAFII	viability after 31 days	AGGTAGTCCCTAGGTAAGAGAGG	KLHL3	ENSG00000146021	0.3479951707318444	[283]	[210,193,NaN]	2	hSpCas9	negative selection	10084769
137677595	137677618	5	-	27869803	HPAFII	viability after 31 days	TCTTAGCCTGAGTCTGGACCAGG	KLHL3	ENSG00000146021	0.5603939905938855	[207]	[286,46,NaN]	4	hSpCas9	negative selection	10084770
137692284	137692307	5	-	27869803	HPAFII	viability after 31 days	CAGCAGGCCAATGCCTACGCAGG	KLHL3	ENSG00000146021	-0.19209059929742422	[235]	[80,153,NaN]	-1	hSpCas9	negative selection	10084771
137709780	137709803	5	+	27869803	HPAFII	viability after 31 days	AGGCTGCCAGGACCACACGGTGG	KLHL3	ENSG00000146021	-0.43317729217150225	[605]	[159,351,NaN]	-3	hSpCas9	negative selection	10084772
137720464	137720487	5	-	27869803	HPAFII	viability after 31 days	AGGTTATGAATGAACTGCGGAGG	KLHL3	ENSG00000146021	0.8286926799886349	[213]	[208,217,NaN]	6	hSpCas9	negative selection	10084773
137639908	137639931	5	-	28162770	P31FUJ	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	0.35415434643886523	[240]	[361]	4	hSpCas9	negative selection	10180508
137639023	137639046	5	+	28162770	P31FUJ	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.005984655172737829	[149]	[176]	0	hSpCas9	negative selection	10180509
137658181	137658204	5	+	28162770	P31FUJ	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.1452204525439101	[226]	[294]	1	hSpCas9	negative selection	10180510
137639050	137639073	5	-	28162770	P31FUJ	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.1585192258906576	[551]	[723]	1	hSpCas9	negative selection	10180511
137637352	137637375	5	-	28162770	P31FUJ	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.4529777958335224	[349]	[562]	5	hSpCas9	negative selection	10180512
137637322	137637345	5	-	28162770	P31FUJ	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	-0.33859686843697556	[98]	[91]	-3	hSpCas9	negative selection	10180513
137634042	137634065	5	-	28162770	P31FUJ	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	-1.2328022044143783	[1]	[0]	-7	hSpCas9	negative selection	10180514
137628398	137628421	5	-	28162770	P31FUJ	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.0216739478722362	[348]	[403]	0	hSpCas9	negative selection	10180515
137639115	137639138	5	-	28162770	P31FUJ	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.6911435553738701	[184]	[350]	7	hSpCas9	negative selection	10180516
137639098	137639121	5	+	28162770	P31FUJ	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.08079003130491991	[971]	[1207]	0	hSpCas9	negative selection	10180517
137639908	137639931	5	-	28162770	TF1	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	NaN	[NaN]	[49]	1	hSpCas9	negative selection	10349874
137639023	137639046	5	+	28162770	TF1	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10349875
137658181	137658204	5	+	28162770	TF1	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10349876
137639050	137639073	5	-	28162770	TF1	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	NaN	[NaN]	[447]	1	hSpCas9	negative selection	10349877
137637352	137637375	5	-	28162770	TF1	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	NaN	[NaN]	[376]	1	hSpCas9	negative selection	10349878
137637322	137637345	5	-	28162770	TF1	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10349879
137634042	137634065	5	-	28162770	TF1	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10349880
137628398	137628421	5	-	28162770	TF1	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	NaN	[NaN]	[133]	1	hSpCas9	negative selection	10349881
137639115	137639138	5	-	28162770	TF1	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10349882
137639098	137639121	5	+	28162770	TF1	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	NaN	[NaN]	[746]	1	hSpCas9	negative selection	10349883
137639908	137639931	5	-	28162770	SKM1	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.518932630385959	[76]	[94]	-4	hSpCas9	negative selection	10519240
137639023	137639046	5	+	28162770	SKM1	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	1.3593280666925562	[27]	[126]	9	hSpCas9	negative selection	10519241
137658181	137658204	5	+	28162770	SKM1	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	1.043980954006307	[61]	[225]	8	hSpCas9	negative selection	10519242
137639050	137639073	5	-	28162770	SKM1	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	-0.08679656172023642	[163]	[272]	0	hSpCas9	negative selection	10519243
137637352	137637375	5	-	28162770	SKM1	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	-0.06711419585853695	[111]	[188]	0	hSpCas9	negative selection	10519244
137637322	137637345	5	-	28162770	SKM1	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	-0.6699986045769555	[26]	[29]	-5	hSpCas9	negative selection	10519245
137634042	137634065	5	-	28162770	SKM1	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10519246
137628398	137628421	5	-	28162770	SKM1	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.3625700793847083	[63]	[87]	-3	hSpCas9	negative selection	10519247
137639115	137639138	5	-	28162770	SKM1	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.6109577092541005	[39]	[107]	6	hSpCas9	negative selection	10519248
137639098	137639121	5	+	28162770	SKM1	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.25014808773382935	[194]	[409]	2	hSpCas9	negative selection	10519249
137639908	137639931	5	-	28162770	SKM1	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.518932630385959	[76]	[94]	-4	hSpCas9	negative selection	10688606
137639023	137639046	5	+	28162770	SKM1	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	1.3593280666925562	[27]	[126]	9	hSpCas9	negative selection	10688607
137658181	137658204	5	+	28162770	SKM1	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	1.043980954006307	[61]	[225]	8	hSpCas9	negative selection	10688608
137639050	137639073	5	-	28162770	SKM1	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	-0.08679656172023642	[163]	[272]	0	hSpCas9	negative selection	10688609
137637352	137637375	5	-	28162770	SKM1	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	-0.06711419585853695	[111]	[188]	0	hSpCas9	negative selection	10688610
137637322	137637345	5	-	28162770	SKM1	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	-0.6699986045769555	[26]	[29]	-5	hSpCas9	negative selection	10688611
137634042	137634065	5	-	28162770	SKM1	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	-0.8220016980220048	[0]	[0]	-6	hSpCas9	negative selection	10688612
137628398	137628421	5	-	28162770	SKM1	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.3625700793847083	[63]	[87]	-3	hSpCas9	negative selection	10688613
137639115	137639138	5	-	28162770	SKM1	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.6109577092541005	[39]	[107]	6	hSpCas9	negative selection	10688614
137639098	137639121	5	+	28162770	SKM1	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.25014808773382935	[194]	[409]	2	hSpCas9	negative selection	10688615
137639908	137639931	5	-	28162770	PL21	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.8792948530050847	[223]	[52]	-6	hSpCas9	negative selection	10857972
137639023	137639046	5	+	28162770	PL21	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	1.6025107019320035	[142]	[188]	9	hSpCas9	negative selection	10857973
137658181	137658204	5	+	28162770	PL21	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-0.8614994513030657	[262]	[62]	-5	hSpCas9	negative selection	10857974
137639050	137639073	5	-	28162770	PL21	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	-0.09239469540323286	[582]	[237]	0	hSpCas9	negative selection	10857975
137637352	137637375	5	-	28162770	PL21	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.9219328970312758	[324]	[267]	7	hSpCas9	negative selection	10857976
137637322	137637345	5	-	28162770	PL21	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	-1.1217884803980422	[144]	[28]	-6	hSpCas9	negative selection	10857977
137634042	137634065	5	-	28162770	PL21	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	1.20013961448932	[0]	[0]	8	hSpCas9	negative selection	10857978
137628398	137628421	5	-	28162770	PL21	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.004791836780905501	[218]	[94]	0	hSpCas9	negative selection	10857979
137639115	137639138	5	-	28162770	PL21	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.9471588733194494	[142]	[119]	7	hSpCas9	negative selection	10857980
137639098	137639121	5	+	28162770	PL21	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.9221838599657715	[621]	[512]	7	hSpCas9	negative selection	10857981
137639908	137639931	5	-	28162770	P31FUJ	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	0.35415434643886523	[240]	[361]	4	hSpCas9	negative selection	11027338
137639023	137639046	5	+	28162770	P31FUJ	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.005984655172737829	[149]	[176]	0	hSpCas9	negative selection	11027339
137658181	137658204	5	+	28162770	P31FUJ	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.1452204525439101	[226]	[294]	1	hSpCas9	negative selection	11027340
137639050	137639073	5	-	28162770	P31FUJ	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.1585192258906576	[551]	[723]	1	hSpCas9	negative selection	11027341
137637352	137637375	5	-	28162770	P31FUJ	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.4529777958335224	[349]	[562]	5	hSpCas9	negative selection	11027342
137637322	137637345	5	-	28162770	P31FUJ	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	-0.33859686843697556	[98]	[91]	-3	hSpCas9	negative selection	11027343
137634042	137634065	5	-	28162770	P31FUJ	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	-1.2328022044143783	[1]	[0]	-7	hSpCas9	negative selection	11027344
137628398	137628421	5	-	28162770	P31FUJ	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.0216739478722362	[348]	[403]	0	hSpCas9	negative selection	11027345
137639115	137639138	5	-	28162770	P31FUJ	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.6911435553738701	[184]	[350]	7	hSpCas9	negative selection	11027346
137639098	137639121	5	+	28162770	P31FUJ	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.08079003130491991	[971]	[1207]	0	hSpCas9	negative selection	11027347
137639908	137639931	5	-	28162770	OCIAML5	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.8782188587199655	[166]	[163]	-5	hSpCas9	negative selection	11196704
137639023	137639046	5	+	28162770	OCIAML5	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.4805087682228738	[53]	[135]	4	hSpCas9	negative selection	11196705
137658181	137658204	5	+	28162770	OCIAML5	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.7677663897042115	[108]	[334]	6	hSpCas9	negative selection	11196706
137639050	137639073	5	-	28162770	OCIAML5	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.4243173886288163	[250]	[607]	3	hSpCas9	negative selection	11196707
137637352	137637375	5	-	28162770	OCIAML5	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.20526660420195475	[221]	[461]	1	hSpCas9	negative selection	11196708
137637322	137637345	5	-	28162770	OCIAML5	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	1.7194754140948376	[17]	[106]	9	hSpCas9	negative selection	11196709
137634042	137634065	5	-	28162770	OCIAML5	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	1.3703258504724505	[2]	[13]	9	hSpCas9	negative selection	11196710
137628398	137628421	5	-	28162770	OCIAML5	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.8024358031393963	[199]	[206]	-5	hSpCas9	negative selection	11196711
137639115	137639138	5	-	28162770	OCIAML5	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	1.5241629084270774	[72]	[378]	9	hSpCas9	negative selection	11196712
137639098	137639121	5	+	28162770	OCIAML5	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.1967928305863107	[478]	[990]	1	hSpCas9	negative selection	11196713
137639908	137639931	5	-	28162770	EOL1	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.31385696775454447	[452]	[191]	-2	hSpCas9	negative selection	11366070
137639023	137639046	5	+	28162770	EOL1	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.898707766635275	[168]	[165]	7	hSpCas9	negative selection	11366071
137658181	137658204	5	+	28162770	EOL1	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.4774094291246665	[408]	[299]	4	hSpCas9	negative selection	11366072
137639050	137639073	5	-	28162770	EOL1	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	-0.27419750590827907	[947]	[412]	-2	hSpCas9	negative selection	11366073
137637352	137637375	5	-	28162770	EOL1	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.15682847727143057	[726]	[426]	1	hSpCas9	negative selection	11366074
137637322	137637345	5	-	28162770	EOL1	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.39021134391934637	[167]	[115]	3	hSpCas9	negative selection	11366075
137634042	137634065	5	-	28162770	EOL1	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	0.924547771570535	[0]	[0]	7	hSpCas9	negative selection	11366076
137628398	137628421	5	-	28162770	EOL1	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.681173289317419	[279]	[91]	-5	hSpCas9	negative selection	11366077
137639115	137639138	5	-	28162770	EOL1	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	-0.7304622266788782	[210]	[66]	-5	hSpCas9	negative selection	11366078
137639098	137639121	5	+	28162770	EOL1	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.42641262360275345	[934]	[661]	4	hSpCas9	negative selection	11366079
137639908	137639931	5	-	28162770	MOLM13	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.0012010214911710223	[280]	[202]	0	hSpCas9	negative selection	11535436
137639023	137639046	5	+	28162770	MOLM13	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	-1.140919861130945	[182]	[59]	-5	hSpCas9	negative selection	11535437
137658181	137658204	5	+	28162770	MOLM13	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.4855913832780376	[323]	[327]	3	hSpCas9	negative selection	11535438
137639050	137639073	5	-	28162770	MOLM13	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.9659162454944543	[683]	[965]	7	hSpCas9	negative selection	11535439
137637352	137637375	5	-	28162770	MOLM13	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.038115339008837346	[655]	[486]	0	hSpCas9	negative selection	11535440
137637322	137637345	5	-	28162770	MOLM13	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.8130248675932663	[147]	[187]	6	hSpCas9	negative selection	11535441
137634042	137634065	5	-	28162770	MOLM13	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	0.4678893815445786	[1]	[1]	3	hSpCas9	negative selection	11535442
137628398	137628421	5	-	28162770	MOLM13	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	0.20680324750030674	[295]	[246]	1	hSpCas9	negative selection	11535443
137639115	137639138	5	-	28162770	MOLM13	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	1.7601987097538858	[186]	[457]	9	hSpCas9	negative selection	11535444
137639098	137639121	5	+	28162770	MOLM13	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.41228167495512924	[1004]	[966]	3	hSpCas9	negative selection	11535445
137639908	137639931	5	-	28162770	HEL	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.24360438620407593	[243]	[131]	-2	hSpCas9	negative selection	11704802
137639023	137639046	5	+	28162770	HEL	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.12248202066701608	[108]	[75]	1	hSpCas9	negative selection	11704803
137658181	137658204	5	+	28162770	HEL	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.9891892460217885	[279]	[355]	8	hSpCas9	negative selection	11704804
137639050	137639073	5	-	28162770	HEL	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.8176335078053343	[643]	[726]	7	hSpCas9	negative selection	11704805
137637352	137637375	5	-	28162770	HEL	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	1.0577763312792008	[509]	[679]	8	hSpCas9	negative selection	11704806
137637322	137637345	5	-	28162770	HEL	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.1646915351957129	[116]	[83]	1	hSpCas9	negative selection	11704807
137634042	137634065	5	-	28162770	HEL	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	0.6427388320003571	[0]	[0]	5	hSpCas9	negative selection	11704808
137628398	137628421	5	-	28162770	HEL	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-1.4208772672956147	[254]	[60]	-7	hSpCas9	negative selection	11704809
137639115	137639138	5	-	28162770	HEL	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.4073607690694284	[185]	[157]	3	hSpCas9	negative selection	11704810
137639098	137639121	5	+	28162770	HEL	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.5017832310694617	[794]	[720]	4	hSpCas9	negative selection	11704811
137639908	137639931	5	-	28162770	MV411	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.6941457629919029	[241]	[125]	-5	hSpCas9	negative selection	11874168
137639023	137639046	5	+	28162770	MV411	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.5469978326416831	[142]	[175]	5	hSpCas9	negative selection	11874169
137658181	137658204	5	+	28162770	MV411	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.12190666869891637	[239]	[219]	1	hSpCas9	negative selection	11874170
137639050	137639073	5	-	28162770	MV411	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.6206548743669922	[524]	[679]	5	hSpCas9	negative selection	11874171
137637352	137637375	5	-	28162770	MV411	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.4148942966343381	[324]	[364]	3	hSpCas9	negative selection	11874172
137637322	137637345	5	-	28162770	MV411	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.33763535975435344	[92]	[98]	3	hSpCas9	negative selection	11874173
137634042	137634065	5	-	28162770	MV411	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	0.24743755078277552	[0]	[0]	2	hSpCas9	negative selection	11874174
137628398	137628421	5	-	28162770	MV411	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	0.5407964934733667	[203]	[249]	5	hSpCas9	negative selection	11874175
137639115	137639138	5	-	28162770	MV411	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.04749998027402334	[169]	[147]	0	hSpCas9	negative selection	11874176
137639098	137639121	5	+	28162770	MV411	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.4867758641732125	[664]	[784]	4	hSpCas9	negative selection	11874177
137639908	137639931	5	-	28162770	MONOMAC1	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	0.11963552237631342	[109]	[136]	1	hSpCas9	negative selection	12043534
137639023	137639046	5	+	28162770	MONOMAC1	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.07859759555387369	[94]	[114]	0	hSpCas9	negative selection	12043535
137658181	137658204	5	+	28162770	MONOMAC1	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	-0.19703684705955382	[167]	[167]	-2	hSpCas9	negative selection	12043536
137639050	137639073	5	-	28162770	MONOMAC1	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.5003263966618443	[324]	[526]	5	hSpCas9	negative selection	12043537
137637352	137637375	5	-	28162770	MONOMAC1	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.23710947516699477	[224]	[303]	2	hSpCas9	negative selection	12043538
137637322	137637345	5	-	28162770	MONOMAC1	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.0888720250268269	[72]	[88]	0	hSpCas9	negative selection	12043539
137634042	137634065	5	-	28162770	MONOMAC1	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	-0.19703684705955382	[0]	[0]	-2	hSpCas9	negative selection	12043540
137628398	137628421	5	-	28162770	MONOMAC1	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	0.46659996778951496	[112]	[178]	4	hSpCas9	negative selection	12043541
137639115	137639138	5	-	28162770	MONOMAC1	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.20092713886034874	[84]	[111]	2	hSpCas9	negative selection	12043542
137639098	137639121	5	+	28162770	MONOMAC1	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.4699046122410975	[552]	[877]	4	hSpCas9	negative selection	12043543
137639908	137639931	5	-	28162770	OCIAML2	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.011198206604863925	[31]	[175]	0	hSpCas9	negative selection	12212900
137639023	137639046	5	+	28162770	OCIAML2	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.2249767391629876	[22]	[148]	2	hSpCas9	negative selection	12212901
137658181	137658204	5	+	28162770	OCIAML2	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.3510329334993263	[42]	[303]	3	hSpCas9	negative selection	12212902
137639050	137639073	5	-	28162770	OCIAML2	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.2813187982499239	[90]	[612]	2	hSpCas9	negative selection	12212903
137637352	137637375	5	-	28162770	OCIAML2	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.9183049581419469	[60]	[638]	8	hSpCas9	negative selection	12212904
137637322	137637345	5	-	28162770	OCIAML2	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	0.6823220975964377	[18]	[168]	6	hSpCas9	negative selection	12212905
137634042	137634065	5	-	28162770	OCIAML2	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	-2.4706298252421615	[0]	[0]	-8	hSpCas9	negative selection	12212906
137628398	137628421	5	-	28162770	OCIAML2	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	0.5041034161474087	[35]	[282]	5	hSpCas9	negative selection	12212907
137639115	137639138	5	-	28162770	OCIAML2	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.06910342148599719	[26]	[156]	0	hSpCas9	negative selection	12212908
137639098	137639121	5	+	28162770	OCIAML2	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.4540820474536016	[117]	[895]	4	hSpCas9	negative selection	12212909
137639908	137639931	5	-	28162770	OCIAML3	viability	GGAGTGCTATGATTTCGAGGAGG	KLHL3	ENSG00000146021	-0.547911225734709	[76]	[158]	-4	hSpCas9	negative selection	12382266
137639023	137639046	5	+	28162770	OCIAML3	viability	GCGCTCCTGCATGCTGGCAATGG	KLHL3	ENSG00000146021	0.3401044240193797	[27]	[106]	3	hSpCas9	negative selection	12382267
137658181	137658204	5	+	28162770	OCIAML3	viability	ATAGTCTCTGATCCAGAGGGAGG	KLHL3	ENSG00000146021	0.1644376812524946	[59]	[202]	1	hSpCas9	negative selection	12382268
137639050	137639073	5	-	28162770	OCIAML3	viability	ATGACGGCGTGAAGGACCAGTGG	KLHL3	ENSG00000146021	0.41323603200246084	[148]	[598]	4	hSpCas9	negative selection	12382269
137637352	137637375	5	-	28162770	OCIAML3	viability	ACAGCTACAAGACCAACGAGTGG	KLHL3	ENSG00000146021	0.6064748280941188	[108]	[500]	5	hSpCas9	negative selection	12382270
137637322	137637345	5	-	28162770	OCIAML3	viability	TGGCCCCGATGAACACGCGGCGG	KLHL3	ENSG00000146021	-1.3387505850820884	[30]	[36]	-7	hSpCas9	negative selection	12382271
137634042	137634065	5	-	28162770	OCIAML3	viability	GACATGAGCACCCGCCGCAGTGG	KLHL3	ENSG00000146021	-1.594007640324163	[0]	[0]	-8	hSpCas9	negative selection	12382272
137628398	137628421	5	-	28162770	OCIAML3	viability	GGACAGCTGTACGCCACAGGTGG	KLHL3	ENSG00000146021	-0.4821147602532659	[61]	[133]	-4	hSpCas9	negative selection	12382273
137639115	137639138	5	-	28162770	OCIAML3	viability	GGCTGGCCACGTGTATGCCGTGG	KLHL3	ENSG00000146021	0.5592386199715189	[28]	[128]	5	hSpCas9	negative selection	12382274
137639098	137639121	5	+	28162770	OCIAML3	viability	TGAGCCATTAAACCCTCCCACGG	KLHL3	ENSG00000146021	0.05352733182866021	[187]	[588]	0	hSpCas9	negative selection	12382275