Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3848
• Symbol:KRT1
• Description:keratin 1

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52680259	52680282	12	-	26472758	Jiyoye	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.9596069491657493	[48]	[18]	-6	hSpCas9	negative selection	86161
52680173	52680196	12	-	26472758	Jiyoye	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.26631284566602376	[171]	[155]	2	hSpCas9	negative selection	86162
52680235	52680258	12	+	26472758	Jiyoye	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	0.14808816018874238	[72]	[60]	1	hSpCas9	negative selection	86163
52678558	52678581	12	-	26472758	Jiyoye	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.06532659249525097	[236]	[186]	0	hSpCas9	negative selection	86164
52677718	52677741	12	-	26472758	Jiyoye	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.2890976479455549	[508]	[468]	2	hSpCas9	negative selection	86165
52677159	52677182	12	-	26472758	Jiyoye	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.02398178313624739	[119]	[88]	0	hSpCas9	negative selection	86166
52676330	52676353	12	-	26472758	Jiyoye	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	3.86660700014317	[0]	[10]	9	hSpCas9	negative selection	86167
52680305	52680328	12	-	26472758	Jiyoye	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.21109320583246116	[240]	[156]	-1	hSpCas9	negative selection	86168
52680200	52680223	12	-	26472758	Jiyoye	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	-0.026581315119559523	[180]	[133]	0	hSpCas9	negative selection	86169
52680095	52680118	12	-	26472758	Jiyoye	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.03469834445507525	[166]	[128]	0	hSpCas9	negative selection	86170
52680259	52680282	12	-	26472758	KBM7	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	1.329833553057018	[92,71]	[120,74]	9	hSpCas9	negative selection	277279
52680173	52680196	12	-	26472758	KBM7	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.5458424172650902	[777,921]	[801,402]	6	hSpCas9	negative selection	277280
52680235	52680258	12	+	26472758	KBM7	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.5298750211540628	[380,283]	[112,101]	-5	hSpCas9	negative selection	277281
52678558	52678581	12	-	26472758	KBM7	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.3534063606414406	[932,873]	[853,265]	4	hSpCas9	negative selection	277282
52677718	52677741	12	-	26472758	KBM7	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.5762662366941651	[2078,1532]	[1343,1170]	6	hSpCas9	negative selection	277283
52677159	52677182	12	-	26472758	KBM7	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.22928898886516236	[351,376]	[129,162]	-2	hSpCas9	negative selection	277284
52676330	52676353	12	-	26472758	KBM7	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	0.47699283321992936	[87,188]	[132,59]	5	hSpCas9	negative selection	277285
52680305	52680328	12	-	26472758	KBM7	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.23874510879708188	[761,779]	[555,317]	2	hSpCas9	negative selection	277286
52680200	52680223	12	-	26472758	KBM7	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.40322515039380974	[461,275]	[202,243]	4	hSpCas9	negative selection	277287
52680095	52680118	12	-	26472758	KBM7	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.05951017760439309	[662,417]	[297,225]	0	hSpCas9	negative selection	277288
52680259	52680282	12	-	26472758	Raji	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	2.370417941207393	[9]	[11]	9	hSpCas9	negative selection	468397
52680173	52680196	12	-	26472758	Raji	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.06990882995493652	[467]	[113]	0	hSpCas9	negative selection	468398
52680235	52680258	12	+	26472758	Raji	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.9307515935131716	[114]	[13]	-6	hSpCas9	negative selection	468399
52678558	52678581	12	-	26472758	Raji	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.19729050772673684	[450]	[119]	1	hSpCas9	negative selection	468400
52677718	52677741	12	-	26472758	Raji	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.4553068387939063	[835]	[265]	4	hSpCas9	negative selection	468401
52677159	52677182	12	-	26472758	Raji	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	0.21902889120250843	[173]	[46]	2	hSpCas9	negative selection	468402
52676330	52676353	12	-	26472758	Raji	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	0.6126188436240216	[61]	[21]	6	hSpCas9	negative selection	468403
52680305	52680328	12	-	26472758	Raji	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.2399671563936696	[457]	[89]	-2	hSpCas9	negative selection	468404
52680200	52680223	12	-	26472758	Raji	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.35844529954131743	[241]	[71]	3	hSpCas9	negative selection	468405
52680095	52680118	12	-	26472758	Raji	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	-0.7232036929217216	[312]	[43]	-5	hSpCas9	negative selection	468406
52680259	52680282	12	-	26472758	K562	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.1761569551538269	[86]	[64]	-1	hSpCas9	negative selection	659515
52680173	52680196	12	-	26472758	K562	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.5351621173682833	[635]	[777]	4	hSpCas9	negative selection	659516
52680235	52680258	12	+	26472758	K562	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.7330387036824649	[253]	[128]	-4	hSpCas9	negative selection	659517
52678558	52678581	12	-	26472758	K562	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	-0.26234224118267113	[762]	[536]	-2	hSpCas9	negative selection	659518
52677718	52677741	12	-	26472758	K562	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.4290386588736248	[1747]	[1095]	-3	hSpCas9	negative selection	659519
52677159	52677182	12	-	26472758	K562	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.16739487073811077	[297]	[223]	-1	hSpCas9	negative selection	659520
52676330	52676353	12	-	26472758	K562	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-4.299901788557364	[69]	[2]	-9	hSpCas9	negative selection	659521
52680305	52680328	12	-	26472758	K562	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.44570861603850775	[696]	[431]	-3	hSpCas9	negative selection	659522
52680200	52680223	12	-	26472758	K562	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	1.2269615305899004	[290]	[574]	9	hSpCas9	negative selection	659523
52680095	52680118	12	-	26472758	K562	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.40177505560570365	[537]	[599]	3	hSpCas9	negative selection	659524
52675572	52675595	12	-	26627737	DLD1	viability	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.4111433023169843	[732]	[132,208,175]	-4	hSpCas9	negative selection	784277
52677715	52677738	12	-	26627737	DLD1	viability	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.29683070646075127	[319]	[46,152,51]	-3	hSpCas9	negative selection	784278
52677718	52677741	12	-	26627737	DLD1	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.5611523538491217	[323]	[67,86,53]	-5	hSpCas9	negative selection	784279
52678621	52678644	12	-	26627737	DLD1	viability	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.5286226022507097	[144]	[88,51,55]	5	hSpCas9	negative selection	784280
52680224	52680247	12	-	26627737	DLD1	viability	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.11474496296386039	[288]	[166,45,41]	-1	hSpCas9	negative selection	784281
52680246	52680269	12	+	26627737	DLD1	viability	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	-0.41894606010355684	[857]	[242,255,117]	-4	hSpCas9	negative selection	784282
52675572	52675595	12	-	26627737	GBM cells	viability after 5 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.906848056427903	[271]	[283,262]	9	hSpCas9	negative selection	866592
52677715	52677738	12	-	26627737	GBM cells	viability after 5 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.24392090328576915	[243]	[122,97]	-4	hSpCas9	negative selection	866593
52677718	52677741	12	-	26627737	GBM cells	viability after 5 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.9848931076097917	[154]	[35,47]	-9	hSpCas9	negative selection	866594
52678621	52678644	12	-	26627737	GBM cells	viability after 5 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.5861264338547918	[117]	[85,103]	8	hSpCas9	negative selection	866595
52680224	52680247	12	-	26627737	GBM cells	viability after 5 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	0.6265416044725557	[92]	[76,76]	8	hSpCas9	negative selection	866596
52680246	52680269	12	+	26627737	GBM cells	viability after 5 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.17867251552910832	[242]	[153,140]	3	hSpCas9	negative selection	866597
52675572	52675595	12	-	26627737	GBM cells	viability after 13 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.618569428921228	[271]	[305,161]	7	hSpCas9	negative selection	948907
52677715	52677738	12	-	26627737	GBM cells	viability after 13 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.029207010142560646	[243]	[153,109]	0	hSpCas9	negative selection	948908
52677718	52677741	12	-	26627737	GBM cells	viability after 13 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.24576902818423396	[154]	[60,78]	-3	hSpCas9	negative selection	948909
52678621	52678644	12	-	26627737	GBM cells	viability after 13 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.26044877037339453	[117]	[79,73]	3	hSpCas9	negative selection	948910
52680224	52680247	12	-	26627737	GBM cells	viability after 13 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.7301492865447865	[92]	[41,20]	-7	hSpCas9	negative selection	948911
52680246	52680269	12	+	26627737	GBM cells	viability after 13 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.4835596999668964	[242]	[185,182]	6	hSpCas9	negative selection	948912
52675572	52675595	12	-	26627737	GBM cells	viability after 21 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.5029646401682022	[271]	[234,185]	5	hSpCas9	negative selection	1031222
52677715	52677738	12	-	26627737	GBM cells	viability after 21 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.3226027808656976	[243]	[170,160]	3	hSpCas9	negative selection	1031223
52677718	52677741	12	-	26627737	GBM cells	viability after 21 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.7520349158838543	[154]	[49,49]	-6	hSpCas9	negative selection	1031224
52678621	52678644	12	-	26627737	GBM cells	viability after 21 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	1.055521821872002	[117]	[150,116]	9	hSpCas9	negative selection	1031225
52680224	52680247	12	-	26627737	GBM cells	viability after 21 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.22856589003659966	[92]	[51,34]	-2	hSpCas9	negative selection	1031226
52680246	52680269	12	+	26627737	GBM cells	viability after 21 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.4603942277008615	[242]	[189,173]	5	hSpCas9	negative selection	1031227
52675572	52675595	12	-	26627737	RPE1	viability after 9 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.48809758666832975	[1181]	[241,291]	-3	hSpCas9	negative selection	1113537
52677715	52677738	12	-	26627737	RPE1	viability after 9 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	1.1434409359926605	[649]	[218,746]	7	hSpCas9	negative selection	1113538
52677718	52677741	12	-	26627737	RPE1	viability after 9 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.607628898211913	[564]	[95,141]	-4	hSpCas9	negative selection	1113539
52678621	52678644	12	-	26627737	RPE1	viability after 9 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.7198698529130299	[350]	[81,46]	-5	hSpCas9	negative selection	1113540
52680224	52680247	12	-	26627737	RPE1	viability after 9 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	3.4309058796058425	[24]	[38,142]	9	hSpCas9	negative selection	1113541
52680246	52680269	12	+	26627737	RPE1	viability after 9 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	1.99091628047156	[361]	[346,583]	8	hSpCas9	negative selection	1113542
52675572	52675595	12	-	26627737	RPE1	viability after 12 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.3613679754873824	[1181]	[168,329]	-2	hSpCas9	negative selection	1195852
52677715	52677738	12	-	26627737	RPE1	viability after 12 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	1.1283808303213005	[649]	[237,533]	6	hSpCas9	negative selection	1195853
52677718	52677741	12	-	26627737	RPE1	viability after 12 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.2392488131888274	[564]	[131,124]	-2	hSpCas9	negative selection	1195854
52678621	52678644	12	-	26627737	RPE1	viability after 12 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.8653704176196784	[350]	[181,160]	5	hSpCas9	negative selection	1195855
52680224	52680247	12	-	26627737	RPE1	viability after 12 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	4.197113667705952	[24]	[27,223]	9	hSpCas9	negative selection	1195856
52680246	52680269	12	+	26627737	RPE1	viability after 12 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	1.951511990063453	[361]	[330,423]	8	hSpCas9	negative selection	1195857
52675572	52675595	12	-	26627737	RPE1	viability after 15 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.5238697202450466	[1181]	[60,397]	-3	hSpCas9	negative selection	1278167
52677715	52677738	12	-	26627737	RPE1	viability after 15 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	1.241866771490726	[649]	[301,562]	7	hSpCas9	negative selection	1278168
52677718	52677741	12	-	26627737	RPE1	viability after 15 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.6246338782890611	[564]	[178,30]	-4	hSpCas9	negative selection	1278169
52678621	52678644	12	-	26627737	RPE1	viability after 15 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.6205631640802192	[350]	[171,133]	4	hSpCas9	negative selection	1278170
52680224	52680247	12	-	26627737	RPE1	viability after 15 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	3.9122344809948917	[24]	[107,104]	9	hSpCas9	negative selection	1278171
52680246	52680269	12	+	26627737	RPE1	viability after 15 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	2.0895706660886644	[361]	[303,562]	8	hSpCas9	negative selection	1278172
52675572	52675595	12	-	26627737	RPE1	viability after 18 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.9309829489577368	[1181]	[117,219]	-5	hSpCas9	negative selection	1360482
52677715	52677738	12	-	26627737	RPE1	viability after 18 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	1.3833066289030944	[649]	[270,656]	7	hSpCas9	negative selection	1360483
52677718	52677741	12	-	26627737	RPE1	viability after 18 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.21151936607114175	[564]	[136,125]	-1	hSpCas9	negative selection	1360484
52678621	52678644	12	-	26627737	RPE1	viability after 18 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.38660614203010746	[350]	[118,128]	2	hSpCas9	negative selection	1360485
52680224	52680247	12	-	26627737	RPE1	viability after 18 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	3.9659712130249556	[24]	[117,91]	9	hSpCas9	negative selection	1360486
52680246	52680269	12	+	26627737	RPE1	viability after 18 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	1.7817938135594762	[361]	[216,462]	8	hSpCas9	negative selection	1360487
52675572	52675595	12	-	26627737	HeLa	viability after 8 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.5366399177057222	[483]	[555,159,258]	5	hSpCas9	negative selection	1442797
52677715	52677738	12	-	26627737	HeLa	viability after 8 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.8642934354793232	[467]	[98,80,149]	-7	hSpCas9	negative selection	1442798
52677718	52677741	12	-	26627737	HeLa	viability after 8 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	1.6660279516660559	[63]	[159,48,72]	9	hSpCas9	negative selection	1442799
52678621	52678644	12	-	26627737	HeLa	viability after 8 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.025928371626513125	[301]	[108,132,139]	0	hSpCas9	negative selection	1442800
52680224	52680247	12	-	26627737	HeLa	viability after 8 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	1.509155566065051	[25]	[42,23,31]	9	hSpCas9	negative selection	1442801
52680246	52680269	12	+	26627737	HeLa	viability after 8 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	1.4517619676072224	[419]	[707,625,230]	8	hSpCas9	negative selection	1442802
52675572	52675595	12	-	26627737	HeLa	viability after 12 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.7505477946713102	[483]	[553,174,303]	6	hSpCas9	negative selection	1525112
52677715	52677738	12	-	26627737	HeLa	viability after 12 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.4072401590104282	[467]	[143,121,173]	-4	hSpCas9	negative selection	1525113
52677718	52677741	12	-	26627737	HeLa	viability after 12 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.9691560351843742	[63]	[86,7,65]	7	hSpCas9	negative selection	1525114
52678621	52678644	12	-	26627737	HeLa	viability after 12 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-1.3860530393372563	[301]	[32,64,42]	-8	hSpCas9	negative selection	1525115
52680224	52680247	12	-	26627737	HeLa	viability after 12 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	2.18674472066479	[25]	[88,0,62]	9	hSpCas9	negative selection	1525116
52680246	52680269	12	+	26627737	HeLa	viability after 12 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.6927252224205398	[419]	[432,252,162]	5	hSpCas9	negative selection	1525117
52675572	52675595	12	-	26627737	HeLa	viability after 15 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.987472899180996	[483]	[518,276,372]	7	hSpCas9	negative selection	1607427
52677715	52677738	12	-	26627737	HeLa	viability after 15 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-1.0903768060841967	[467]	[23,134,111]	-7	hSpCas9	negative selection	1607428
52677718	52677741	12	-	26627737	HeLa	viability after 15 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.5613726704940207	[63]	[56,32,23]	4	hSpCas9	negative selection	1607429
52678621	52678644	12	-	26627737	HeLa	viability after 15 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.3176885085604947	[301]	[145,114,28]	-3	hSpCas9	negative selection	1607430
52680224	52680247	12	-	26627737	HeLa	viability after 15 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	1.4165932543810613	[25]	[6,1,79]	8	hSpCas9	negative selection	1607431
52680246	52680269	12	+	26627737	HeLa	viability after 15 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.6296989147941452	[419]	[402,158,226]	5	hSpCas9	negative selection	1607432
52675572	52675595	12	-	26627737	HeLa	viability after 18 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.9604085920713181	[483]	[335,226,372]	7	hSpCas9	negative selection	1689742
52677715	52677738	12	-	26627737	HeLa	viability after 18 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-1.0602719835813574	[467]	[17,113,111]	-7	hSpCas9	negative selection	1689743
52677718	52677741	12	-	26627737	HeLa	viability after 18 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.6779656506813747	[63]	[43,27,23]	5	hSpCas9	negative selection	1689744
52678621	52678644	12	-	26627737	HeLa	viability after 18 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.269914730677828	[301]	[102,96,28]	-2	hSpCas9	negative selection	1689745
52680224	52680247	12	-	26627737	HeLa	viability after 18 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	1.462534041077229	[25]	[6,0,79]	8	hSpCas9	negative selection	1689746
52680246	52680269	12	+	26627737	HeLa	viability after 18 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.6038874213264496	[419]	[264,126,226]	5	hSpCas9	negative selection	1689747
52675572	52675595	12	-	26627737	HCT116	viability after 6 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.905581084142038	[1375]	[70,139]	-5	hSpCas9	negative selection	1772057
52677715	52677738	12	-	26627737	HCT116	viability after 6 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.4230852678583408	[540]	[46,150]	2	hSpCas9	negative selection	1772058
52677718	52677741	12	-	26627737	HCT116	viability after 6 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-3.25467257610753	[405]	[16,0]	-9	hSpCas9	negative selection	1772059
52678621	52678644	12	-	26627737	HCT116	viability after 6 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.6676908116615636	[252]	[64,2]	-4	hSpCas9	negative selection	1772060
52680224	52680247	12	-	26627737	HCT116	viability after 6 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.06737067705016808	[285]	[49,38]	0	hSpCas9	negative selection	1772061
52680246	52680269	12	+	26627737	HCT116	viability after 6 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	-1.3379065100403986	[1579]	[134,77]	-6	hSpCas9	negative selection	1772062
52675572	52675595	12	-	26627737	HCT116	viability after 8 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.9307226798656065	[297]	[311,311,314]	8	hSpCas9	negative selection	1854372
52677715	52677738	12	-	26627737	HCT116	viability after 8 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.4486257215269625	[244]	[172,151,226]	5	hSpCas9	negative selection	1854373
52677718	52677741	12	-	26627737	HCT116	viability after 8 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.6652935490393919	[258]	[73,48,145]	-7	hSpCas9	negative selection	1854374
52678621	52678644	12	-	26627737	HCT116	viability after 8 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.11891963107179016	[118]	[63,38,77]	-1	hSpCas9	negative selection	1854375
52680224	52680247	12	-	26627737	HCT116	viability after 8 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.4585780826077346	[169]	[29,37,134]	-5	hSpCas9	negative selection	1854376
52680246	52680269	12	+	26627737	HCT116	viability after 8 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.2109907342661856	[388]	[275,235,232]	2	hSpCas9	negative selection	1854377
52675572	52675595	12	-	26627737	HCT116	viability after 9 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.3754689899656215	[1375]	[385,201]	-3	hSpCas9	negative selection	1936687
52677715	52677738	12	-	26627737	HCT116	viability after 9 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.807463991305445	[540]	[105,63]	-5	hSpCas9	negative selection	1936688
52677718	52677741	12	-	26627737	HCT116	viability after 9 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.14426817570460715	[405]	[154,91]	1	hSpCas9	negative selection	1936689
52678621	52678644	12	-	26627737	HCT116	viability after 9 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.1682998411779304	[252]	[120,11]	-1	hSpCas9	negative selection	1936690
52680224	52680247	12	-	26627737	HCT116	viability after 9 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.5499497588984279	[285]	[83,26]	-4	hSpCas9	negative selection	1936691
52680246	52680269	12	+	26627737	HCT116	viability after 9 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	-0.050780600854760216	[1579]	[103,646]	0	hSpCas9	negative selection	1936692
52675572	52675595	12	-	26627737	HCT116	viability after 12 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	1.568144321389428	[297]	[424,398,570]	9	hSpCas9	negative selection	2019002
52677715	52677738	12	-	26627737	HCT116	viability after 12 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.16836695840218313	[244]	[110,101,222]	1	hSpCas9	negative selection	2019003
52677718	52677741	12	-	26627737	HCT116	viability after 12 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.10399672569677289	[258]	[121,187,131]	1	hSpCas9	negative selection	2019004
52678621	52678644	12	-	26627737	HCT116	viability after 12 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.14400729032092263	[118]	[38,83,48]	-1	hSpCas9	negative selection	2019005
52680224	52680247	12	-	26627737	HCT116	viability after 12 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.7685001527421662	[169]	[6,38,114]	-7	hSpCas9	negative selection	2019006
52680246	52680269	12	+	26627737	HCT116	viability after 12 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.9708634469967521	[388]	[582,398,203]	8	hSpCas9	negative selection	2019007
52675572	52675595	12	-	26627737	HCT116	viability after 15 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.9192065566508321	[297]	[335,277,357]	7	hSpCas9	negative selection	2101317
52677715	52677738	12	-	26627737	HCT116	viability after 15 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.29011954297514514	[244]	[221,110,188]	3	hSpCas9	negative selection	2101318
52677718	52677741	12	-	26627737	HCT116	viability after 15 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.10815913709797872	[258]	[124,114,171]	-1	hSpCas9	negative selection	2101319
52678621	52678644	12	-	26627737	HCT116	viability after 15 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.33392020643368414	[118]	[63,57,41]	-3	hSpCas9	negative selection	2101320
52680224	52680247	12	-	26627737	HCT116	viability after 15 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-1.0305859966130764	[169]	[22,39,76]	-8	hSpCas9	negative selection	2101321
52680246	52680269	12	+	26627737	HCT116	viability after 15 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.24696144833555594	[388]	[275,366,154]	2	hSpCas9	negative selection	2101322
52675572	52675595	12	-	26627737	HCT116	viability after 18 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	1.1191378504074163	[297]	[233,223,494]	8	hSpCas9	negative selection	2183632
52677715	52677738	12	-	26627737	HCT116	viability after 18 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.29502643094164677	[244]	[140,103,195]	2	hSpCas9	negative selection	2183633
52677718	52677741	12	-	26627737	HCT116	viability after 18 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.38300541425880075	[258]	[143,169,175]	3	hSpCas9	negative selection	2183634
52678621	52678644	12	-	26627737	HCT116	viability after 18 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	-0.45615549913329834	[118]	[36,67,17]	-4	hSpCas9	negative selection	2183635
52680224	52680247	12	-	26627737	HCT116	viability after 18 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	-0.48366761110041545	[169]	[53,54,67]	-4	hSpCas9	negative selection	2183636
52680246	52680269	12	+	26627737	HCT116	viability after 18 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.20371322631655336	[388]	[390,159,96]	1	hSpCas9	negative selection	2183637
52679887	52679910	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCTTGTATGCCACCAGGAGGG	KRT1	ENSG00000167768	-0.455195641459007	[3,3]	[3,1]	-6	hSpCas9	positive selection	2998105
52679823	52679846	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GATTGACCCTGAGATCCAAAAGG	KRT1	ENSG00000167768	0.5030348072287844	[3,3]	[6,2]	8	hSpCas9	positive selection	2998106
52679838	52679861	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGTCAATCTCCACATTGAGGGG	KRT1	ENSG00000167768	0.23367975794523987	[4,5]	[4,5]	5	hSpCas9	positive selection	2998107
52680304	52680327	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTCTGGGTACCGAAGTGGAGGG	KRT1	ENSG00000167768	-0.510096485207693	[3,3]	[2,1]	-6	hSpCas9	positive selection	2998108
52679887	52679910	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCTTGTATGCCACCAGGAGGG	KRT1	ENSG00000167768	-0.2921659414952694	[3,3]	[3,1]	-4	hSpCas9	positive selection	3065963
52679823	52679846	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GATTGACCCTGAGATCCAAAAGG	KRT1	ENSG00000167768	-0.5060561728088999	[3,3]	[2,0]	-7	hSpCas9	positive selection	3065964
52679838	52679861	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGTCAATCTCCACATTGAGGGG	KRT1	ENSG00000167768	0.18525295407136777	[4,4]	[4,3]	3	hSpCas9	positive selection	3065965
52680304	52680327	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTCTGGGTACCGAAGTGGAGGG	KRT1	ENSG00000167768	-0.12859553882174227	[3,3]	[3,1]	-2	hSpCas9	positive selection	3065966
52678628	52678651		-	24336571	A375	resistance to PLX after 7 days	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.11761250816607954	[8,8]	[6,9]	-4	hSpCas9	positive selection	3123712
52678597	52678620		+	24336571	A375	resistance to PLX after 7 days	GAGATTGATCACTCTTCAGTTGG	KRT1	ENSG00000167768	0.16445881162828213	[6,5]	[9,4]	5	hSpCas9	positive selection	3123713
52678162	52678185		-	24336571	A375	resistance to PLX after 7 days	TGAATTTGTGACCATCAAGAAGG	KRT1	ENSG00000167768	0.4417141383986708	[3,4]	[5,7]	9	hSpCas9	positive selection	3123714
52678628	52678651		-	24336571	A375	resistance to PLX after 14 days	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.19847960976351342	[6,9]	[4,3]	2	hSpCas9	positive selection	3181505
52678597	52678620		+	24336571	A375	resistance to PLX after 14 days	GAGATTGATCACTCTTCAGTTGG	KRT1	ENSG00000167768	0.0036362817226261446	[9,7]	[3,3]	0	hSpCas9	positive selection	3181506
52678162	52678185		-	24336571	A375	resistance to PLX after 14 days	TGAATTTGTGACCATCAAGAAGG	KRT1	ENSG00000167768	1.0411360147533673	[2,2]	[3,1]	8	hSpCas9	positive selection	3181507
52678628	52678651		-	24336571	A375	viability after 7 days	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.6612416489216678	[14]	[8,8]	-7	hSpCas9	negative selection	3239298
52678597	52678620		+	24336571	A375	viability after 7 days	GAGATTGATCACTCTTCAGTTGG	KRT1	ENSG00000167768	0.11303148882149416	[5]	[6,5]	1	hSpCas9	negative selection	3239299
52678162	52678185		-	24336571	A375	viability after 7 days	TGAATTTGTGACCATCAAGAAGG	KRT1	ENSG00000167768	-1.0812551769166412	[10]	[3,4]	-9	hSpCas9	negative selection	3239300
52678628	52678651		-	24336571	A375	viability after 14 days	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.7340300755023774	[14]	[6,9]	-7	hSpCas9	negative selection	3297091
52678597	52678620		+	24336571	A375	viability after 14 days	GAGATTGATCACTCTTCAGTTGG	KRT1	ENSG00000167768	0.5608198422493769	[5]	[9,7]	7	hSpCas9	negative selection	3297092
52678162	52678185		-	24336571	A375	viability after 14 days	TGAATTTGTGACCATCAAGAAGG	KRT1	ENSG00000167768	-1.667818116636218	[10]	[2,2]	-9	hSpCas9	negative selection	3297093
52677649	52677672	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.18051061439500407	[134,134]	[0,0]	1	hSpCas9	positive selection	3376234
52677683	52677706	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	-1.032692635486783	[312,312]	[0,0]	-7	hSpCas9	positive selection	3376235
52677426	52677449	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	-0.1177132199010895	[165,165]	[0,0]	0	hSpCas9	positive selection	3376236
52679886	52679909	12	+	26780180	HT29	viability (Avana library 4 designs)	CTTCTTGTATGCCACCAGGAGGG	KRT1	ENSG00000167768	0.648372970627297	[]	[]	2	hSpCas9	negative selection	3435557
52679823	52679846	12	-	26780180	HT29	viability (Avana library 4 designs)	GATTGACCCTGAGATCCAAAAGG	KRT1	ENSG00000167768	0.205271735078696	[]	[]	0	hSpCas9	negative selection	3435558
52679837	52679860	12	+	26780180	HT29	viability (Avana library 4 designs)	GGGTCAATCTCCACATTGAGGGG	KRT1	ENSG00000167768	-0.176773287930555	[]	[]	-3	hSpCas9	negative selection	3435559
52680304	52680327	12	-	26780180	HT29	viability (Avana library 4 designs)	GGTCTGGGTACCGAAGTGGAGGG	KRT1	ENSG00000167768	0.473788379412627	[]	[]	1	hSpCas9	negative selection	3435560
52679886	52679909	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCTTGTATGCCACCAGGAGGG	KRT1	ENSG00000167768	1.45090064814609	[]	[]	2	hSpCas9	negative selection	3523183
52679837	52679860	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTCAATCTCCACATTGAGGGG	KRT1	ENSG00000167768	3.7554431589604	[]	[]	6	hSpCas9	negative selection	3523184
52679823	52679846	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GATTGACCCTGAGATCCAAAAGG	KRT1	ENSG00000167768	-1.274279595655	[]	[]	-1	hSpCas9	negative selection	3523185
52680304	52680327	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGTCTGGGTACCGAAGTGGAGGG	KRT1	ENSG00000167768	2.74993243405692	[]	[]	4	hSpCas9	negative selection	3523186
52677718	52677741	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	2.94597621029937	[]	[]	4	hSpCas9	negative selection	3523187
52679885	52679908	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTTCTTGTATGCCACCAGGAGG	KRT1	ENSG00000167768	0.195794673233981	[]	[]	0	hSpCas9	negative selection	3523188
52679886	52679909	12	+	26780180	A375	viability (Avana lentiGuide)	CTTCTTGTATGCCACCAGGAGGG	KRT1	ENSG00000167768	-2.97153616650809	[]	[]	-5	hSpCas9	negative selection	3631842
52679837	52679860	12	+	26780180	A375	viability (Avana lentiGuide)	GGGTCAATCTCCACATTGAGGGG	KRT1	ENSG00000167768	-1.41943859620345	[]	[]	-2	hSpCas9	negative selection	3631843
52679823	52679846	12	-	26780180	A375	viability (Avana lentiGuide)	GATTGACCCTGAGATCCAAAAGG	KRT1	ENSG00000167768	-5.91025543966651	[]	[]	-8	hSpCas9	negative selection	3631844
52680304	52680327	12	-	26780180	A375	viability (Avana lentiGuide)	GGTCTGGGTACCGAAGTGGAGGG	KRT1	ENSG00000167768	2.64524418658747	[]	[]	3	hSpCas9	negative selection	3631845
52677718	52677741	12	-	26780180	A375	viability (Avana lentiGuide)	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	11.739877188377	[]	[]	7	hSpCas9	negative selection	3631846
52679885	52679908	12	+	26780180	A375	viability (Avana lentiGuide)	ACTTCTTGTATGCCACCAGGAGG	KRT1	ENSG00000167768	-0.328563400573976	[]	[]	0	hSpCas9	negative selection	3631847
52679886	52679909	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCTTGTATGCCACCAGGAGGG	KRT1	ENSG00000167768	-0.15825385613561518	[5]	[4,3]	-3	hSpCas9	positive selection	3740501
52679837	52679860	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTCAATCTCCACATTGAGGGG	KRT1	ENSG00000167768	0.14976012921200177	[6]	[6,6]	4	hSpCas9	positive selection	3740502
52679823	52679846	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATTGACCCTGAGATCCAAAAGG	KRT1	ENSG00000167768	-0.0510052583593207	[5]	[5,4]	-1	hSpCas9	positive selection	3740503
52680304	52680327	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTCTGGGTACCGAAGTGGAGGG	KRT1	ENSG00000167768	0.3487379951222547	[4]	[5,6]	9	hSpCas9	positive selection	3740504
52677718	52677741	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.045975560536577226	[5]	[6,4]	1	hSpCas9	positive selection	3740505
52679885	52679908	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTTCTTGTATGCCACCAGGAGG	KRT1	ENSG00000167768	0.15299566853414312	[4]	[5,5]	4	hSpCas9	positive selection	3740506
52679886	52679909	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCTTGTATGCCACCAGGAGGG	KRT1	ENSG00000167768	-0.10837195607817438	[5]	[4,4]	-1	hSpCas9	positive selection	3849108
52679837	52679860	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTCAATCTCCACATTGAGGGG	KRT1	ENSG00000167768	-0.08791230123877417	[6]	[4,5]	-1	hSpCas9	positive selection	3849109
52679823	52679846	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATTGACCCTGAGATCCAAAAGG	KRT1	ENSG00000167768	0.1256373964133963	[4]	[5,3]	3	hSpCas9	positive selection	3849110
52680304	52680327	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTCTGGGTACCGAAGTGGAGGG	KRT1	ENSG00000167768	0.2202056278845664	[5]	[5,4]	5	hSpCas9	positive selection	3849111
52677718	52677741	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.08314286100510684	[5]	[3,4]	-1	hSpCas9	positive selection	3849112
52679885	52679908	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTTCTTGTATGCCACCAGGAGG	KRT1	ENSG00000167768	-0.4216990504006465	[4]	[4,0]	-5	hSpCas9	positive selection	3849113
52677426	52677449	12	-	26780180	A375	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	1.08722323211494	[]	[]	5	hSpCas9	negative selection	3955193
52677402	52677425	12	-	26780180	A375	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	1.77650291740393	[]	[]	9	hSpCas9	negative selection	3955194
52678628	52678651	12	-	26780180	A375	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	1.04405240563236	[]	[]	5	hSpCas9	negative selection	3955195
52678664	52678687	12	+	26780180	A375	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.659940328419777	[]	[]	2	hSpCas9	negative selection	3955196
52677683	52677706	12	+	26780180	A375	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.988411721028162	[]	[]	4	hSpCas9	negative selection	3955197
52677649	52677672	12	+	26780180	A375	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.494918894648545	[]	[]	1	hSpCas9	negative selection	3955198
52677426	52677449	12	-	26780180	HT29	viability (GeCKOv2 library)	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	1.00372038021019	[]	[]	4	hSpCas9	negative selection	4063159
52677402	52677425	12	-	26780180	HT29	viability (GeCKOv2 library)	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	1.29448547477655	[]	[]	6	hSpCas9	negative selection	4063160
52678628	52678651	12	-	26780180	HT29	viability (GeCKOv2 library)	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	1.04156729636864	[]	[]	5	hSpCas9	negative selection	4063161
52678664	52678687	12	+	26780180	HT29	viability (GeCKOv2 library)	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	-0.285321775374454	[]	[]	-7	hSpCas9	negative selection	4063162
52677683	52677706	12	+	26780180	HT29	viability (GeCKOv2 library)	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	1.01291651329571	[]	[]	4	hSpCas9	negative selection	4063163
52677649	52677672	12	+	26780180	HT29	viability (GeCKOv2 library)	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.528668536634468	[]	[]	1	hSpCas9	negative selection	4063164
52678628	52678651	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	1.0358356955099042	[2]	[6,1]	9	hSpCas9	positive selection	4147670
52678597	52678620	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGATTGATCACTCTTCAGTTGG	KRT1	ENSG00000167768	-0.01174216574369974	[2]	[1,1]	0	hSpCas9	positive selection	4147671
52678162	52678185	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAATTTGTGACCATCAAGAAGG	KRT1	ENSG00000167768	-0.11724581822528907	[2]	[1,1]	-3	hSpCas9	positive selection	4147672
52678628	52678651	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.9106626922022241	[4]	[1,3,3,3]	6	hSpCas9	positive selection	4211692
52678597	52678620	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGATTGATCACTCTTCAGTTGG	KRT1	ENSG00000167768	1.323099329518415	[2]	[3,0,1,3]	9	hSpCas9	positive selection	4211693
52678162	52678185	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAATTTGTGACCATCAAGAAGG	KRT1	ENSG00000167768	2.5442002339899625	[0]	[3,2,0,4]	9	hSpCas9	positive selection	4211694
52678628	52678651	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.41276367167135875	[2]	[2,1]	8	hSpCas9	positive selection	4279089
52678664	52678687	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.4129098863835615	[2]	[2,2]	8	hSpCas9	positive selection	4279090
52677402	52677425	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.48027838289382746	[3]	[2,0]	-8	hSpCas9	positive selection	4279091
52677649	52677672	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	-0.04693548349602892	[2]	[3,0]	-1	hSpCas9	positive selection	4343344
52677683	52677706	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.23501557388140082	[3]	[3,2]	5	hSpCas9	positive selection	4343345
52677426	52677449	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.012951499308315587	[3]	[3,1]	0	hSpCas9	positive selection	4343346
52677735	52677757	12	-	27760321	OCIAML3	viability	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	1.3606513654228622	[316,349]	[471,938]	9	hSpCas9	negative selection	4413039
52678642	52678664	12	+	27760321	OCIAML3	viability	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	-0.4685640365116446	[78,71]	[13,79]	-5	hSpCas9	negative selection	4413040
52679805	52679827	12	-	27760321	OCIAML3	viability	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	-0.03767078967596449	[65,49]	[22,70]	0	hSpCas9	negative selection	4413041
52680194	52680216	12	-	27760321	OCIAML3	viability	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	0.5309960756162109	[1062,948]	[1011,1295]	6	hSpCas9	negative selection	4413042
52680259	52680281	12	-	27760321	OCIAML3	viability	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.007027892994641793	[802,750]	[555,668]	0	hSpCas9	negative selection	4413043
52677735	52677757	12	-	27760321	OCIAML2	viability	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.2557819570691382	[316,349]	[273,390]	3	hSpCas9	negative selection	4496502
52678642	52678664	12	+	27760321	OCIAML2	viability	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	0.20720154298297544	[78,71]	[63,78]	2	hSpCas9	negative selection	4496503
52679805	52679827	12	-	27760321	OCIAML2	viability	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	-0.8162943434098842	[65,49]	[25,26]	-7	hSpCas9	negative selection	4496504
52680194	52680216	12	-	27760321	OCIAML2	viability	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	0.2522830256154953	[1062,948]	[904,1050]	3	hSpCas9	negative selection	4496505
52680259	52680281	12	-	27760321	OCIAML2	viability	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.09962066405544467	[802,750]	[568,811]	1	hSpCas9	negative selection	4496506
52677735	52677757	12	-	27760321	MV411	viability	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.5807130261133491	[316,349]	[285,399]	4	hSpCas9	negative selection	4579965
52678642	52678664	12	+	27760321	MV411	viability	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	1.138920162363319	[78,71]	[181,0]	8	hSpCas9	negative selection	4579966
52679805	52679827	12	-	27760321	MV411	viability	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	0.5335259907482799	[65,49]	[0,135]	4	hSpCas9	negative selection	4579967
52680194	52680216	12	-	27760321	MV411	viability	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	0.4572573371251165	[1062,948]	[653,1294]	3	hSpCas9	negative selection	4579968
52680259	52680281	12	-	27760321	MV411	viability	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.22062129140261233	[802,750]	[283,674]	-1	hSpCas9	negative selection	4579969
52677735	52677757	12	-	27760321	HL60	viability	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.37818489318449894	[316,349]	[345,367]	5	hSpCas9	negative selection	4663428
52678642	52678664	12	+	27760321	HL60	viability	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	1.1784720163479132	[78,71]	[106,173]	9	hSpCas9	negative selection	4663429
52679805	52679827	12	-	27760321	HL60	viability	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	-1.8508424708397029	[65,49]	[13,11]	-9	hSpCas9	negative selection	4663430
52680194	52680216	12	-	27760321	HL60	viability	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.0895915462812038	[1062,948]	[712,832]	-1	hSpCas9	negative selection	4663431
52680259	52680281	12	-	27760321	HL60	viability	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.12124548824539894	[802,750]	[714,664]	1	hSpCas9	negative selection	4663432
52677735	52677757	12	-	27760321	HT1080	viability	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.11947335382479014	[349,272]	[98,173]	0	hSpCas9	negative selection	4746891
52678642	52678664	12	+	27760321	HT1080	viability	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	1.584559573370038	[71,55]	[106,42]	8	hSpCas9	negative selection	4746892
52679805	52679827	12	-	27760321	HT1080	viability	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	-4.147863326691041	[49,38]	[0,0]	-8	hSpCas9	negative selection	4746893
52680194	52680216	12	-	27760321	HT1080	viability	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.0016522265651257584	[948,740]	[351,318]	0	hSpCas9	negative selection	4746894
52680259	52680281	12	-	27760321	HT1080	viability	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.06336274995172975	[750,585]	[251,257]	0	hSpCas9	negative selection	4746895
52677735	52677757	12	-	27760321	HT29	viability after 7 days	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.15608584193175784	[349,272]	[547,561,248]	2	hSpCas9	negative selection	4830354
52678642	52678664	12	+	27760321	HT29	viability after 7 days	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	0.32423436375620796	[71,55]	[18,19,252]	5	hSpCas9	negative selection	4830355
52679805	52679827	12	-	27760321	HT29	viability after 7 days	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	-0.3176592379272867	[49,38]	[84,36,21]	-4	hSpCas9	negative selection	4830356
52680194	52680216	12	-	27760321	HT29	viability after 7 days	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.21648837140919253	[948,740]	[1088,839,897]	-3	hSpCas9	negative selection	4830357
52680259	52680281	12	-	27760321	HT29	viability after 7 days	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.1828893723524586	[750,585]	[800,539,929]	-3	hSpCas9	negative selection	4830358
52677735	52677757	12	-	27760321	HT29	viability after 25 days	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.16283911822229455	[349,272]	[322,328,564]	1	hSpCas9	negative selection	4913817
52678642	52678664	12	+	27760321	HT29	viability after 25 days	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	0.4591386368782824	[71,55]	[77,122,101]	5	hSpCas9	negative selection	4913818
52679805	52679827	12	-	27760321	HT29	viability after 25 days	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	0.47429796324354045	[49,38]	[81,93,30]	5	hSpCas9	negative selection	4913819
52680194	52680216	12	-	27760321	HT29	viability after 25 days	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.12948874336504113	[948,740]	[785,830,1053]	-1	hSpCas9	negative selection	4913820
52680259	52680281	12	-	27760321	HT29	viability after 25 days	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.21793627866098753	[750,585]	[674,594,1467]	2	hSpCas9	negative selection	4913821
52677735	52677757	12	-	27760321	HT29	viability after 22 days	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.04970582336399609	[349,272]	[396,293,426]	0	hSpCas9	negative selection	4997280
52678642	52678664	12	+	27760321	HT29	viability after 22 days	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	0.5774500243723688	[71,55]	[151,68,108]	6	hSpCas9	negative selection	4997281
52679805	52679827	12	-	27760321	HT29	viability after 22 days	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	0.3166774384376474	[49,38]	[162,17,7]	3	hSpCas9	negative selection	4997282
52680194	52680216	12	-	27760321	HT29	viability after 22 days	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.1275388841007996	[948,740]	[903,926,850]	-1	hSpCas9	negative selection	4997283
52680259	52680281	12	-	27760321	HT29	viability after 22 days	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.019646520735196793	[750,585]	[735,566,1050]	0	hSpCas9	negative selection	4997284
52677735	52677757	12	-	27760321	HT29	viability after 19 days	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	-0.21304870134783263	[349,272]	[289,215,409]	-2	hSpCas9	negative selection	5080743
52678642	52678664	12	+	27760321	HT29	viability after 19 days	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	-0.8484192931040013	[71,55]	[45,76,0]	-6	hSpCas9	negative selection	5080744
52679805	52679827	12	-	27760321	HT29	viability after 19 days	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	-1.3480633187575983	[49,38]	[41,19,0]	-7	hSpCas9	negative selection	5080745
52680194	52680216	12	-	27760321	HT29	viability after 19 days	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.2792756799117032	[948,740]	[948,565,885]	-3	hSpCas9	negative selection	5080746
52680259	52680281	12	-	27760321	HT29	viability after 19 days	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.032427035593635356	[750,585]	[1068,409,891]	0	hSpCas9	negative selection	5080747
52677735	52677757	12	-	27760321	HT29	viability after 16 days	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	0.35212352715052975	[349,272]	[564,397,383]	4	hSpCas9	negative selection	5164206
52678642	52678664	12	+	27760321	HT29	viability after 16 days	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	-0.1229088493191508	[71,55]	[64,32,99]	-1	hSpCas9	negative selection	5164207
52679805	52679827	12	-	27760321	HT29	viability after 16 days	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	0.6129199633767559	[49,38]	[69,145,9]	7	hSpCas9	negative selection	5164208
52680194	52680216	12	-	27760321	HT29	viability after 16 days	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	0.00755486813726014	[948,740]	[817,853,1168]	0	hSpCas9	negative selection	5164209
52680259	52680281	12	-	27760321	HT29	viability after 16 days	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.24237501162330255	[750,585]	[730,477,700]	-3	hSpCas9	negative selection	5164210
52677735	52677757	12	-	27760321	HT29	viability after 13 days	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	-0.16777583351953304	[349,272]	[262,343,355]	-2	hSpCas9	negative selection	5247669
52678642	52678664	12	+	27760321	HT29	viability after 13 days	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	-0.990376098870084	[71,55]	[30,24,54]	-7	hSpCas9	negative selection	5247670
52679805	52679827	12	-	27760321	HT29	viability after 13 days	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	1.7561763912155473	[49,38]	[226,223,77]	9	hSpCas9	negative selection	5247671
52680194	52680216	12	-	27760321	HT29	viability after 13 days	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.19520685411731353	[948,740]	[749,930,885]	-2	hSpCas9	negative selection	5247672
52680259	52680281	12	-	27760321	HT29	viability after 13 days	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.2471985607234839	[750,585]	[752,487,714]	-3	hSpCas9	negative selection	5247673
52677735	52677757	12	-	27760321	HT29	viability after 10 days	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	-0.029210795149875735	[349,272]	[419,337,383]	0	hSpCas9	negative selection	5331132
52678642	52678664	12	+	27760321	HT29	viability after 10 days	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	-0.5527589466596186	[71,55]	[80,34,46]	-6	hSpCas9	negative selection	5331133
52679805	52679827	12	-	27760321	HT29	viability after 10 days	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	0.7317645608654768	[49,38]	[53,193,32]	8	hSpCas9	negative selection	5331134
52680194	52680216	12	-	27760321	HT29	viability after 10 days	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	-0.1766760173971118	[948,740]	[822,1058,921]	-2	hSpCas9	negative selection	5331135
52680259	52680281	12	-	27760321	HT29	viability after 10 days	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.09982935576306295	[750,585]	[945,1107,640]	1	hSpCas9	negative selection	5331136
52677735	52677757	12	-	27760321	MOLM13	viability	TGTTCCTCTAGGATGTGGATGG	KRT1	ENSG00000167768	1.188052164172696	[316,349]	[500,372]	8	hSpCas9	negative selection	5414595
52678642	52678664	12	+	27760321	MOLM13	viability	TGATGAATGACTCAAAGTAGGG	KRT1	ENSG00000167768	-0.12221290478349056	[78,71]	[50,28]	-1	hSpCas9	negative selection	5414596
52679805	52679827	12	-	27760321	MOLM13	viability	AAGGTGAAGTCTCGAGAAAGGG	KRT1	ENSG00000167768	-0.0800200245110183	[65,49]	[0,55]	0	hSpCas9	negative selection	5414597
52680194	52680216	12	-	27760321	MOLM13	viability	GATTTTCAAGCTGTGGTGGTGG	KRT1	ENSG00000167768	1.2888537487725897	[1062,948]	[1002,1709]	8	hSpCas9	negative selection	5414598
52680259	52680281	12	-	27760321	MOLM13	viability	GATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.96166528926107	[802,750]	[1368,415]	6	hSpCas9	negative selection	5414599
52680365	52680388	12	+	27661255	K562	viability	GTAGGAGCAAGGTAGAGTAAGGG	KRT1	ENSG00000167768	0.03684867833045691	[1042,1055]	[922,805]	1	dCas9-KRAB	negative selection	5489215
52680369	52680392	12	+	27661255	K562	viability	GAGCAAGGTAGAGTAAGGGAAGG	KRT1	ENSG00000167768	0.05470650460682158	[444,417]	[379,339]	1	dCas9-KRAB	negative selection	5489216
52679975	52679998	12	-	27661255	K562	viability	GGCTTTGGTGGTTTTGGCAGTGG	KRT1	ENSG00000167768	0.17838841945296963	[641,839]	[732,609]	6	dCas9-KRAB	negative selection	5489217
52680319	52680342	12	-	27661255	K562	viability	GACAGTTTAGTTCCAGGTCTGGG	KRT1	ENSG00000167768	0.3728746916293959	[86,204]	[157,140]	9	dCas9-KRAB	negative selection	5489218
52678628	52678651	12	-	27260156	BXPC3	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.23219388423101284	[226]	[239,346,244,280]	5	hSpCas9	negative selection	5551549
52678664	52678687	12	+	27260156	BXPC3	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5451906993717639	[299]	[538,308,429,561]	9	hSpCas9	negative selection	5551550
52677402	52677425	12	-	27260156	BXPC3	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.07018936070711848	[536]	[450,505,487,723]	-2	hSpCas9	negative selection	5551551
52677649	52677672	12	+	27260156	BXPC3	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	-0.10799343332940595	[414]	[344,391,499,375]	-3	hSpCas9	negative selection	5615804
52677683	52677706	12	+	27260156	BXPC3	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.0671547536209107	[540]	[534,449,715,694]	1	hSpCas9	negative selection	5615805
52677426	52677449	12	-	27260156	BXPC3	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.07027425727454273	[563]	[468,518,698,835]	1	hSpCas9	negative selection	5615806
52678628	52678651	12	-	27260156	A673	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.26795486017864767	[226]	[324,311,346,327]	6	hSpCas9	negative selection	5672800
52678664	52678687	12	+	27260156	A673	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.6094178014992233	[299]	[593,535,506,566]	9	hSpCas9	negative selection	5672801
52677402	52677425	12	-	27260156	A673	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.047565512248515324	[536]	[577,582,635,696]	-1	hSpCas9	negative selection	5672802
52677649	52677672	12	+	27260156	A673	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	-0.11800500555394092	[414]	[424,376,453,584]	-3	hSpCas9	negative selection	5737055
52677683	52677706	12	+	27260156	A673	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.08024806503754875	[540]	[747,706,535,766]	2	hSpCas9	negative selection	5737056
52677426	52677449	12	-	27260156	A673	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.1644863226611743	[563]	[839,633,792,780]	4	hSpCas9	negative selection	5737057
52678628	52678651	12	-	27260156	A375	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.16539391883663934	[226]	[176,309,403,297]	2	hSpCas9	negative selection	5794051
52678664	52678687	12	+	27260156	A375	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.8662139857086197	[299]	[520,845,524,682]	9	hSpCas9	negative selection	5794052
52677402	52677425	12	-	27260156	A375	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.13718984636185505	[536]	[531,893,633,719]	2	hSpCas9	negative selection	5794053
52677649	52677672	12	+	27260156	A375	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.4871969596949607	[414]	[435,938,561,797]	7	hSpCas9	negative selection	5858306
52677683	52677706	12	+	27260156	A375	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.4066778456404717	[540]	[865,1046,721,751]	6	hSpCas9	negative selection	5858307
52677426	52677449	12	-	27260156	A375	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.2900719005732585	[563]	[1001,772,712,735]	4	hSpCas9	negative selection	5858308
52678628	52678651	12	-	27260156	COLO741	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.2761799487869362	[226]	[367,316,367]	6	hSpCas9	negative selection	5915302
52678664	52678687	12	+	27260156	COLO741	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.20158382688309706	[299]	[464,439,419]	4	hSpCas9	negative selection	5915303
52677402	52677425	12	-	27260156	COLO741	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.12963806819008689	[536]	[846,824,597]	2	hSpCas9	negative selection	5915304
52677649	52677672	12	+	27260156	COLO741	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.04121497019451184	[414]	[644,552,452]	0	hSpCas9	negative selection	5979557
52677683	52677706	12	+	27260156	COLO741	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.0076219490850759075	[540]	[686,651,739]	0	hSpCas9	negative selection	5979558
52677426	52677449	12	-	27260156	COLO741	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.0617795060944718	[563]	[638,931,679]	1	hSpCas9	negative selection	5979559
52678628	52678651	12	-	27260156	CAL120	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.05915785500992565	[226]	[346,335,143]	-1	hSpCas9	negative selection	6036553
52678664	52678687	12	+	27260156	CAL120	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5333226800915651	[299]	[675,421,542]	7	hSpCas9	negative selection	6036554
52677402	52677425	12	-	27260156	CAL120	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.09069472503822806	[536]	[973,713,489]	1	hSpCas9	negative selection	6036555
52677649	52677672	12	+	27260156	CAL120	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.022841038143842557	[414]	[526,403,640]	0	hSpCas9	negative selection	6100808
52677683	52677706	12	+	27260156	CAL120	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.11578574442875886	[540]	[929,654,634]	1	hSpCas9	negative selection	6100809
52677426	52677449	12	-	27260156	CAL120	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	-0.08451773208035271	[563]	[769,698,534]	-1	hSpCas9	negative selection	6100810
52678628	52678651	12	-	27260156	CADOES1	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.3378851467244881	[226]	[347,165,258,294]	5	hSpCas9	negative selection	6157804
52678664	52678687	12	+	27260156	CADOES1	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.8620339785999378	[299]	[491,550,470,514]	9	hSpCas9	negative selection	6157805
52677402	52677425	12	-	27260156	CADOES1	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.08690143446007037	[536]	[465,486,483,442]	-1	hSpCas9	negative selection	6157806
52677649	52677672	12	+	27260156	CADOES1	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.21330740089500783	[414]	[550,312,435,490]	3	hSpCas9	negative selection	6222059
52677683	52677706	12	+	27260156	CADOES1	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.3526724488489138	[540]	[748,565,753,494]	6	hSpCas9	negative selection	6222060
52677426	52677449	12	-	27260156	CADOES1	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.2431576464923274	[563]	[692,673,580,531]	4	hSpCas9	negative selection	6222061
52678628	52678651	12	-	27260156	EWS502	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.40868995000602837	[226]	[279,269,486,241]	7	hSpCas9	negative selection	6279055
52678664	52678687	12	+	27260156	EWS502	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.7244751199676812	[299]	[741,338,529,463]	9	hSpCas9	negative selection	6279056
52677402	52677425	12	-	27260156	EWS502	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.029959628829404422	[536]	[496,457,693,592]	0	hSpCas9	negative selection	6279057
52677649	52677672	12	+	27260156	EWS502	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.12556318209467515	[414]	[350,594,444,539]	2	hSpCas9	negative selection	6343310
52677683	52677706	12	+	27260156	EWS502	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.31768930538219	[540]	[588,673,867,743]	5	hSpCas9	negative selection	6343311
52677426	52677449	12	-	27260156	EWS502	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.2107922221548425	[563]	[637,811,530,787]	3	hSpCas9	negative selection	6343312
52678628	52678651	12	-	27260156	EW8	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.5836089544438516	[226]	[367,234,257,253]	8	hSpCas9	negative selection	6400306
52678664	52678687	12	+	27260156	EW8	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.48215474083779475	[299]	[311,351,305,389]	8	hSpCas9	negative selection	6400307
52677402	52677425	12	-	27260156	EW8	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.24897476316593278	[536]	[361,343,372,382]	-5	hSpCas9	negative selection	6400308
52677649	52677672	12	+	27260156	EW8	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.04353090436651644	[414]	[461,309,329,298]	0	hSpCas9	negative selection	6464561
52677683	52677706	12	+	27260156	EW8	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.3566439152328025	[540]	[581,606,408,673]	6	hSpCas9	negative selection	6464562
52677426	52677449	12	-	27260156	EW8	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.12817509467791632	[563]	[624,547,458,385]	2	hSpCas9	negative selection	6464563
52678628	52678651	12	-	27260156	CORL105	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.1384695617750883	[226]	[241,349,297,277]	2	hSpCas9	negative selection	6521557
52678664	52678687	12	+	27260156	CORL105	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5258724319224036	[299]	[421,370,590,650]	8	hSpCas9	negative selection	6521558
52677402	52677425	12	-	27260156	CORL105	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.18369726332889078	[536]	[455,498,697,580]	-3	hSpCas9	negative selection	6521559
52677649	52677672	12	+	27260156	CORL105	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.003806711085590525	[414]	[518,402,681,377]	0	hSpCas9	negative selection	6585812
52677683	52677706	12	+	27260156	CORL105	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.3205612249467862	[540]	[691,667,818,986]	6	hSpCas9	negative selection	6585813
52677426	52677449	12	-	27260156	CORL105	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.07182971637265101	[563]	[615,654,854,672]	1	hSpCas9	negative selection	6585814
52678628	52678651	12	-	27260156	HS294T	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.035131462890120035	[226]	[77,92,101,86]	0	hSpCas9	negative selection	6642808
52678664	52678687	12	+	27260156	HS294T	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.4795299889158856	[299]	[135,125,101,310]	6	hSpCas9	negative selection	6642809
52677402	52677425	12	-	27260156	HS294T	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.37663755107749797	[536]	[318,393,161,177]	5	hSpCas9	negative selection	6642810
52677649	52677672	12	+	27260156	HS294T	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.45106087744511236	[414]	[206,141,194,359]	6	hSpCas9	negative selection	6707063
52677683	52677706	12	+	27260156	HS294T	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.48896815389171333	[540]	[345,261,193,381]	6	hSpCas9	negative selection	6707064
52677426	52677449	12	-	27260156	HS294T	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.46496931172007505	[563]	[205,264,328,435]	6	hSpCas9	negative selection	6707065
52678628	52678651	12	-	27260156	HCC44	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.656733559046359	[226]	[288,309,751,329]	9	hSpCas9	negative selection	6764059
52678664	52678687	12	+	27260156	HCC44	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.2009847935132928	[299]	[295,390,507,373]	3	hSpCas9	negative selection	6764060
52677402	52677425	12	-	27260156	HCC44	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.2598367936426231	[536]	[499,382,691,498]	-4	hSpCas9	negative selection	6764061
52677649	52677672	12	+	27260156	HCC44	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.46457946382477444	[414]	[861,574,611,562]	7	hSpCas9	negative selection	6828314
52677683	52677706	12	+	27260156	HCC44	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.4443847464747892	[540]	[995,652,1301,504]	7	hSpCas9	negative selection	6828315
52677426	52677449	12	-	27260156	HCC44	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.18008270751124184	[563]	[736,660,826,688]	3	hSpCas9	negative selection	6828316
52678628	52678651	12	-	27260156	G402	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.24145488510668767	[226]	[384,346,343,245]	3	hSpCas9	negative selection	6885310
52678664	52678687	12	+	27260156	G402	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	1.1276393872438883	[299]	[1247,394,1017,586]	9	hSpCas9	negative selection	6885311
52677402	52677425	12	-	27260156	G402	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.2915741451852546	[536]	[1490,575,691,544]	3	hSpCas9	negative selection	6885312
52677649	52677672	12	+	27260156	G402	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.03755093863607317	[414]	[720,384,574,421]	0	hSpCas9	negative selection	6949565
52677683	52677706	12	+	27260156	G402	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.835090724096008	[540]	[1337,728,1858,795]	9	hSpCas9	negative selection	6949566
52677426	52677449	12	-	27260156	G402	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.10631192636504305	[563]	[1088,869,504,562]	1	hSpCas9	negative selection	6949567
52678628	52678651	12	-	27260156	L33	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.6576063680650734	[226]	[384,135,213,373]	9	hSpCas9	negative selection	7006561
52678664	52678687	12	+	27260156	L33	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.4502810220715102	[299]	[408,138,252,487]	8	hSpCas9	negative selection	7006562
52677402	52677425	12	-	27260156	L33	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.22252920754630842	[536]	[515,176,332,362]	-5	hSpCas9	negative selection	7006563
52677649	52677672	12	+	27260156	L33	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.016783517826613775	[414]	[355,170,277,464]	0	hSpCas9	negative selection	7070816
52677683	52677706	12	+	27260156	L33	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.15260164835182002	[540]	[650,226,359,625]	3	hSpCas9	negative selection	7070817
52677426	52677449	12	-	27260156	L33	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.042691160977616105	[563]	[636,207,288,715]	1	hSpCas9	negative selection	7070818
52678628	52678651	12	-	27260156	K562	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.4328939710955704	[226]	[129,390,304,256]	5	hSpCas9	negative selection	7127812
52678664	52678687	12	+	27260156	K562	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.751903926083868	[299]	[385,410,431,543]	8	hSpCas9	negative selection	7127813
52677402	52677425	12	-	27260156	K562	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.33811668601322475	[536]	[438,254,301,494]	-4	hSpCas9	negative selection	7127814
52677649	52677672	12	+	27260156	K562	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.13507716963472982	[414]	[571,523,163,378]	1	hSpCas9	negative selection	7192067
52677683	52677706	12	+	27260156	K562	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.5809464805153556	[540]	[670,835,817,564]	7	hSpCas9	negative selection	7192068
52677426	52677449	12	-	27260156	K562	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.5757843014981514	[563]	[950,839,667,564]	7	hSpCas9	negative selection	7192069
52678628	52678651	12	-	27260156	HT29	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.3354469162977708	[226]	[325,333,340,381]	6	hSpCas9	negative selection	7249063
52678664	52678687	12	+	27260156	HT29	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.8318883824020871	[299]	[711,694,601,597]	9	hSpCas9	negative selection	7249064
52677402	52677425	12	-	27260156	HT29	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.06865568815650948	[536]	[632,612,524,703]	-1	hSpCas9	negative selection	7249065
52677649	52677672	12	+	27260156	HT29	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.25809496993326697	[414]	[587,627,493,688]	5	hSpCas9	negative selection	7313318
52677683	52677706	12	+	27260156	HT29	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.15793112978153942	[540]	[899,733,741,584]	3	hSpCas9	negative selection	7313319
52677426	52677449	12	-	27260156	HT29	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.06497410298588008	[563]	[803,972,647,494]	1	hSpCas9	negative selection	7313320
52678628	52678651	12	-	27260156	MHHES1	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.5199917989247507	[226]	[516,233,372,343]	8	hSpCas9	negative selection	7370314
52678664	52678687	12	+	27260156	MHHES1	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.8588326480565585	[299]	[689,596,614,555]	9	hSpCas9	negative selection	7370315
52677402	52677425	12	-	27260156	MHHES1	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.01934304928580452	[536]	[626,914,607,323]	0	hSpCas9	negative selection	7370316
52677649	52677672	12	+	27260156	MHHES1	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.19291147313706086	[414]	[587,640,701,273]	3	hSpCas9	negative selection	7434569
52677683	52677706	12	+	27260156	MHHES1	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	-0.0422954362399629	[540]	[898,746,503,319]	0	hSpCas9	negative selection	7434570
52677426	52677449	12	-	27260156	MHHES1	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.29255542498354437	[563]	[1046,720,738,644]	5	hSpCas9	negative selection	7434571
52678628	52678651	12	-	27260156	MEWO	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.3356185189970199	[226]	[309,281,219]	7	hSpCas9	negative selection	7491565
52678664	52678687	12	+	27260156	MEWO	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5840473165107474	[299]	[496,397,381]	9	hSpCas9	negative selection	7491566
52677402	52677425	12	-	27260156	MEWO	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.03548345749077467	[536]	[495,502,541]	0	hSpCas9	negative selection	7491567
52677649	52677672	12	+	27260156	MEWO	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	-0.22641731580135951	[414]	[357,246,395]	-5	hSpCas9	negative selection	7555820
52677683	52677706	12	+	27260156	MEWO	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.13249445705467786	[540]	[680,511,495]	3	hSpCas9	negative selection	7555821
52677426	52677449	12	-	27260156	MEWO	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.12012140520827741	[563]	[697,452,593]	2	hSpCas9	negative selection	7555822
52678628	52678651	12	-	27260156	LNCAPCLONEFGC	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.07358382580013523	[226]	[132,164,199,369]	1	hSpCas9	negative selection	7612816
52678664	52678687	12	+	27260156	LNCAPCLONEFGC	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5129385465605558	[299]	[389,387,415,360]	7	hSpCas9	negative selection	7612817
52677402	52677425	12	-	27260156	LNCAPCLONEFGC	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.15119377607433263	[536]	[369,415,473,499]	-2	hSpCas9	negative selection	7612818
52677649	52677672	12	+	27260156	LNCAPCLONEFGC	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.7835467209835943	[414]	[789,563,675,564]	9	hSpCas9	negative selection	7677071
52677683	52677706	12	+	27260156	LNCAPCLONEFGC	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.47466252359185523	[540]	[744,470,625,885]	7	hSpCas9	negative selection	7677072
52677426	52677449	12	-	27260156	LNCAPCLONEFGC	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.061261015780142314	[563]	[544,482,539,567]	0	hSpCas9	negative selection	7677073
52678628	52678651	12	-	27260156	PANC0327	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.09579288282635168	[226]	[296,145,130,194]	-1	hSpCas9	negative selection	7734067
52678664	52678687	12	+	27260156	PANC0327	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.3550903389136496	[299]	[358,268,313,431]	5	hSpCas9	negative selection	7734068
52677402	52677425	12	-	27260156	PANC0327	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.051638654810830936	[536]	[426,398,471,547]	-1	hSpCas9	negative selection	7734069
52677649	52677672	12	+	27260156	PANC0327	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.1459601223441588	[414]	[460,459,338,368]	2	hSpCas9	negative selection	7798322
52677683	52677706	12	+	27260156	PANC0327	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.3322215171998937	[540]	[713,532,544,645]	5	hSpCas9	negative selection	7798323
52677426	52677449	12	-	27260156	PANC0327	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	-0.1387472689725246	[563]	[266,404,445,692]	-2	hSpCas9	negative selection	7798324
52678628	52678651	12	-	27260156	NCIH2009	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.41361731335026186	[226]	[471,446,356]	6	hSpCas9	negative selection	7855318
52678664	52678687	12	+	27260156	NCIH2009	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.2301873087975192	[299]	[486,447,538]	3	hSpCas9	negative selection	7855319
52677402	52677425	12	-	27260156	NCIH2009	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.10323867744097712	[536]	[621,757,697]	-1	hSpCas9	negative selection	7855320
52677649	52677672	12	+	27260156	NCIH2009	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.47157969713375014	[414]	[925,623,887]	6	hSpCas9	negative selection	7919573
52677683	52677706	12	+	27260156	NCIH2009	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.267730820918167	[540]	[865,674,1182]	3	hSpCas9	negative selection	7919574
52677426	52677449	12	-	27260156	NCIH2009	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.1602074184164461	[563]	[1237,758,715]	2	hSpCas9	negative selection	7919575
52678628	52678651	12	-	27260156	NCIH1373	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.37174910168384	[226]	[221,329,325,111]	3	hSpCas9	negative selection	7976569
52678664	52678687	12	+	27260156	NCIH1373	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5775278338134139	[299]	[623,309,570,141]	6	hSpCas9	negative selection	7976570
52677402	52677425	12	-	27260156	NCIH1373	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.7154699592498344	[536]	[442,321,322,103]	-6	hSpCas9	negative selection	7976571
52677649	52677672	12	+	27260156	NCIH1373	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.749358807021532	[414]	[578,1049,662,202]	7	hSpCas9	negative selection	8040824
52677683	52677706	12	+	27260156	NCIH1373	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.6801283518531961	[540]	[1070,588,1384,230]	6	hSpCas9	negative selection	8040825
52677426	52677449	12	-	27260156	NCIH1373	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.7421960440450731	[563]	[1049,1079,1060,269]	7	hSpCas9	negative selection	8040826
52678628	52678651	12	-	27260156	PATU8902	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.9000577243867878	[226]	[724,407,267,1095]	8	hSpCas9	negative selection	8097820
52678664	52678687	12	+	27260156	PATU8902	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	1.5534162469186432	[299]	[1337,974,1013,1674]	9	hSpCas9	negative selection	8097821
52677402	52677425	12	-	27260156	PATU8902	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.08213840697855279	[536]	[977,940,551,743]	0	hSpCas9	negative selection	8097822
52677649	52677672	12	+	27260156	PATU8902	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.11535412719379715	[414]	[714,403,740,604]	1	hSpCas9	negative selection	8162075
52677683	52677706	12	+	27260156	PATU8902	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.2238306906830642	[540]	[677,827,932,1086]	2	hSpCas9	negative selection	8162076
52677426	52677449	12	-	27260156	PATU8902	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.5284886578373172	[563]	[821,1227,958,1621]	5	hSpCas9	negative selection	8162077
52678628	52678651	12	-	27260156	PANC1	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.6706085310056589	[226]	[187,431,458,203]	9	hSpCas9	negative selection	8219071
52678664	52678687	12	+	27260156	PANC1	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.7443601320117357	[299]	[577,455,447,266]	9	hSpCas9	negative selection	8219072
52677402	52677425	12	-	27260156	PANC1	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.30778470253699874	[536]	[331,973,461,589]	5	hSpCas9	negative selection	8219073
52677649	52677672	12	+	27260156	PANC1	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	-0.24105966395298364	[414]	[145,479,270,337]	-4	hSpCas9	negative selection	8283326
52677683	52677706	12	+	27260156	PANC1	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.3784118225569777	[540]	[559,754,549,576]	6	hSpCas9	negative selection	8283327
52677426	52677449	12	-	27260156	PANC1	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.23064090335744625	[563]	[508,821,494,501]	3	hSpCas9	negative selection	8283328
52678628	52678651	12	-	27260156	PANC0813	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.3250438253992759	[226]	[233,355,494,246]	5	hSpCas9	negative selection	8340322
52678664	52678687	12	+	27260156	PANC0813	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5154210501802802	[299]	[523,561,571,365]	7	hSpCas9	negative selection	8340323
52677402	52677425	12	-	27260156	PANC0813	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.06989390487780739	[536]	[616,977,391,654]	1	hSpCas9	negative selection	8340324
52677649	52677672	12	+	27260156	PANC0813	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.3814235428050656	[414]	[811,578,548,615]	6	hSpCas9	negative selection	8404577
52677683	52677706	12	+	27260156	PANC0813	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.139052174645276	[540]	[866,712,676,563]	2	hSpCas9	negative selection	8404578
52677426	52677449	12	-	27260156	PANC0813	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.06902502743984712	[563]	[486,672,913,686]	1	hSpCas9	negative selection	8404579
52678628	52678651	12	-	27260156	RDES	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.04432436013309382	[226]	[218,192,305,310]	0	hSpCas9	negative selection	8461573
52678664	52678687	12	+	27260156	RDES	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.5237141292140584	[299]	[417,428,531,635]	8	hSpCas9	negative selection	8461574
52677402	52677425	12	-	27260156	RDES	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.0874981710053496	[536]	[459,538,681,674]	-1	hSpCas9	negative selection	8461575
52677649	52677672	12	+	27260156	RDES	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.2247388672647805	[414]	[490,471,620,671]	3	hSpCas9	negative selection	8525828
52677683	52677706	12	+	27260156	RDES	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.3471922256804555	[540]	[761,705,714,999]	5	hSpCas9	negative selection	8525829
52677426	52677449	12	-	27260156	RDES	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.10754924518222869	[563]	[538,678,854,751]	1	hSpCas9	negative selection	8525830
52678628	52678651	12	-	27260156	PC3	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.5871168163720577	[226]	[247,282,652,301]	9	hSpCas9	negative selection	8582824
52678664	52678687	12	+	27260156	PC3	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.4004977401503029	[299]	[216,364,673,480]	8	hSpCas9	negative selection	8582825
52677402	52677425	12	-	27260156	PC3	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.008190634925720586	[536]	[298,570,718,670]	0	hSpCas9	negative selection	8582826
52677649	52677672	12	+	27260156	PC3	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.41889275267155235	[414]	[386,438,1279,403]	8	hSpCas9	negative selection	8647079
52677683	52677706	12	+	27260156	PC3	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	-0.07562211477883074	[540]	[417,379,753,577]	-2	hSpCas9	negative selection	8647080
52677426	52677449	12	-	27260156	PC3	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.2579862976434486	[563]	[327,672,1302,731]	5	hSpCas9	negative selection	8647081
52678628	52678651	12	-	27260156	PATU8988T	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.3840821593212802	[226]	[136,205,192,136]	-6	hSpCas9	negative selection	8704075
52678664	52678687	12	+	27260156	PATU8988T	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.16221363743715916	[299]	[482,402,214,194]	3	hSpCas9	negative selection	8704076
52677402	52677425	12	-	27260156	PATU8988T	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.06027924334265644	[536]	[625,546,606,369]	1	hSpCas9	negative selection	8704077
52677649	52677672	12	+	27260156	PATU8988T	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.2231109671554306	[414]	[467,297,631,454]	4	hSpCas9	negative selection	8768330
52677683	52677706	12	+	27260156	PATU8988T	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	-0.2297265140345032	[540]	[377,676,371,372]	-4	hSpCas9	negative selection	8768331
52677426	52677449	12	-	27260156	PATU8988T	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.3620700217739661	[563]	[784,716,627,671]	6	hSpCas9	negative selection	8768332
52678628	52678651	12	-	27260156	T47D	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.443902734079033	[226]	[379,324,409,324]	8	hSpCas9	negative selection	8825326
52678664	52678687	12	+	27260156	T47D	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.6128323590682869	[299]	[579,484,543,532]	9	hSpCas9	negative selection	8825327
52677402	52677425	12	-	27260156	T47D	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.428010107355664	[536]	[420,364,411,677]	-7	hSpCas9	negative selection	8825328
52677649	52677672	12	+	27260156	T47D	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.03187055687345203	[414]	[511,442,548,475]	0	hSpCas9	negative selection	8889581
52677683	52677706	12	+	27260156	T47D	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	-0.011293105459645597	[540]	[670,541,606,690]	0	hSpCas9	negative selection	8889582
52677426	52677449	12	-	27260156	T47D	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.17519839733970438	[563]	[783,678,778,729]	4	hSpCas9	negative selection	8889583
52678628	52678651	12	-	27260156	SU8686	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.21438680102810015	[226]	[275,251,225,291]	3	hSpCas9	negative selection	8946577
52678664	52678687	12	+	27260156	SU8686	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.8204176801531339	[299]	[441,458,555,684]	9	hSpCas9	negative selection	8946578
52677402	52677425	12	-	27260156	SU8686	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.32601414259091877	[536]	[435,352,420,506]	-5	hSpCas9	negative selection	8946579
52677649	52677672	12	+	27260156	SU8686	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.1776810388232919	[414]	[474,315,529,574]	3	hSpCas9	negative selection	9010832
52677683	52677706	12	+	27260156	SU8686	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.15458555837333257	[540]	[484,536,682,721]	2	hSpCas9	negative selection	9010833
52677426	52677449	12	-	27260156	SU8686	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.027964236404846854	[563]	[499,490,701,611]	0	hSpCas9	negative selection	9010834
52678628	52678651	12	-	27260156	SKES1	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	-0.15725130540573762	[226]	[209,300,98,212]	-3	hSpCas9	negative selection	9067828
52678664	52678687	12	+	27260156	SKES1	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.11272186863996159	[299]	[354,328,305,307]	2	hSpCas9	negative selection	9067829
52677402	52677425	12	-	27260156	SKES1	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.14773914960673207	[536]	[408,568,538,418]	-3	hSpCas9	negative selection	9067830
52677649	52677672	12	+	27260156	SKES1	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.2785838437331165	[414]	[499,438,608,451]	6	hSpCas9	negative selection	9132083
52677683	52677706	12	+	27260156	SKES1	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.2715861010900483	[540]	[829,748,619,459]	6	hSpCas9	negative selection	9132084
52677426	52677449	12	-	27260156	SKES1	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	-0.0633214962486778	[563]	[649,510,479,521]	-1	hSpCas9	negative selection	9132085
52678628	52678651	12	-	27260156	TOV112D	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.523250481679977	[226]	[368,325,221,390]	8	hSpCas9	negative selection	9189079
52678664	52678687	12	+	27260156	TOV112D	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.09249716453170165	[299]	[329,324,384,244]	1	hSpCas9	negative selection	9189080
52677402	52677425	12	-	27260156	TOV112D	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.13193696962736656	[536]	[450,633,440,468]	-3	hSpCas9	negative selection	9189081
52677649	52677672	12	+	27260156	TOV112D	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	-0.10136246211963887	[414]	[400,621,233,351]	-2	hSpCas9	negative selection	9253334
52677683	52677706	12	+	27260156	TOV112D	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	-0.07959225052222173	[540]	[481,530,414,620]	-1	hSpCas9	negative selection	9253335
52677426	52677449	12	-	27260156	TOV112D	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.432441227207218	[563]	[715,1562,521,448]	7	hSpCas9	negative selection	9253336
52678628	52678651	12	-	27260156	TC71	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.2273283192640455	[226]	[313,181,339,301]	5	hSpCas9	negative selection	9310330
52678664	52678687	12	+	27260156	TC71	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.6467639589137388	[299]	[455,463,470,632]	9	hSpCas9	negative selection	9310331
52677402	52677425	12	-	27260156	TC71	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	-0.48055811316853725	[536]	[411,412,344,486]	-8	hSpCas9	negative selection	9310332
52677649	52677672	12	+	27260156	TC71	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.02115847434610235	[414]	[416,380,464,548]	0	hSpCas9	negative selection	9374585
52677683	52677706	12	+	27260156	TC71	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.04910188215018321	[540]	[546,549,678,623]	1	hSpCas9	negative selection	9374586
52677426	52677449	12	-	27260156	TC71	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.03314231300510534	[563]	[562,623,648,639]	0	hSpCas9	negative selection	9374587
52678628	52678651	12	-	27260156	TC32	viability	CATTCATCAACAATCTCCGAAGG	KRT1	ENSG00000167768	0.5449910970020267	[226]	[272,238,382,379]	8	hSpCas9	negative selection	9431581
52678664	52678687	12	+	27260156	TC32	viability	CTCTAAATTATGGGTTCTAGTGG	KRT1	ENSG00000167768	0.6000592909892742	[299]	[352,286,587,554]	8	hSpCas9	negative selection	9431582
52677402	52677425	12	-	27260156	TC32	viability	CAACAACCGCAGTCTCGACCTGG	KRT1	ENSG00000167768	0.05902115468341107	[536]	[363,535,691,522]	1	hSpCas9	negative selection	9431583
52677649	52677672	12	+	27260156	TC32	viability	CTGCTTGGTAGAGTGCTGTAAGG	KRT1	ENSG00000167768	0.27495527396193586	[414]	[337,474,540,534]	5	hSpCas9	negative selection	9495836
52677683	52677706	12	+	27260156	TC32	viability	CTGCTGCAAGTTGTCAAGTTTGG	KRT1	ENSG00000167768	0.4611563347882133	[540]	[598,564,830,857]	7	hSpCas9	negative selection	9495837
52677426	52677449	12	-	27260156	TC32	viability	AACTAATGTCATCCTCTCTATGG	KRT1	ENSG00000167768	0.043857408506165596	[563]	[513,443,751,518]	0	hSpCas9	negative selection	9495838
52675572	52675595	12	-	27869803	HPAFII	viability after 27 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.8627992644730771	[360]	[165,52,NaN]	-6	hSpCas9	negative selection	9547277
52677715	52677738	12	-	27869803	HPAFII	viability after 27 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-1.246006875519714	[250]	[83,31,NaN]	-7	hSpCas9	negative selection	9547278
52677718	52677741	12	-	27869803	HPAFII	viability after 27 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.61635835602501	[118]	[120,74,NaN]	5	hSpCas9	negative selection	9547279
52678621	52678644	12	-	27869803	HPAFII	viability after 27 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.6985696308307886	[95]	[130,40,NaN]	5	hSpCas9	negative selection	9547280
52680224	52680247	12	-	27869803	HPAFII	viability after 27 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	1.9832717113909282	[81]	[194,149,NaN]	9	hSpCas9	negative selection	9547281
52680246	52680269	12	+	27869803	HPAFII	viability after 27 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.39729611733981723	[252]	[250,111,NaN]	3	hSpCas9	negative selection	9547282
52675572	52675595	12	-	27869803	HPAFII	viability after 15 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.15926824818417146	[360]	[442,287,NaN]	-2	hSpCas9	negative selection	9629726
52677715	52677738	12	-	27869803	HPAFII	viability after 15 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.6835494179511364	[250]	[265,106,NaN]	-6	hSpCas9	negative selection	9629727
52677718	52677741	12	-	27869803	HPAFII	viability after 15 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.48201599109046167	[118]	[288,109,NaN]	5	hSpCas9	negative selection	9629728
52678621	52678644	12	-	27869803	HPAFII	viability after 15 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.8002374485479631	[95]	[347,74,NaN]	8	hSpCas9	negative selection	9629729
52680224	52680247	12	-	27869803	HPAFII	viability after 15 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	0.4906335516218252	[81]	[211,68,NaN]	5	hSpCas9	negative selection	9629730
52680246	52680269	12	+	27869803	HPAFII	viability after 15 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.4382969972696099	[252]	[381,359,NaN]	5	hSpCas9	negative selection	9629731
52675572	52675595	12	-	27869803	ASPC1	viability after 36 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.9700772598076466	[925]	[720,544,634]	8	hSpCas9	negative selection	9712175
52677715	52677738	12	-	27869803	ASPC1	viability after 36 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-0.36098859902537833	[562]	[230,66,164]	-4	hSpCas9	negative selection	9712176
52677718	52677741	12	-	27869803	ASPC1	viability after 36 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.7940450134771057	[410]	[167,73,28]	-7	hSpCas9	negative selection	9712177
52678621	52678644	12	-	27869803	ASPC1	viability after 36 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.6630632661947808	[306]	[80,286,136]	6	hSpCas9	negative selection	9712178
52680224	52680247	12	-	27869803	ASPC1	viability after 36 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	0.50376012023099	[337]	[94,217,175]	5	hSpCas9	negative selection	9712179
52680246	52680269	12	+	27869803	ASPC1	viability after 36 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.18855136247422588	[883]	[751,148,227]	1	hSpCas9	negative selection	9712180
52675572	52675595	12	-	27869803	PATU8988S	viability after 35 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.3732551991180284	[807]	[425,416,NaN]	4	hSpCas9	negative selection	9794624
52677715	52677738	12	-	27869803	PATU8988S	viability after 35 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.7032743921617896	[560]	[314,420,NaN]	7	hSpCas9	negative selection	9794625
52677718	52677741	12	-	27869803	PATU8988S	viability after 35 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.6257702934212082	[332]	[182,230,NaN]	7	hSpCas9	negative selection	9794626
52678621	52678644	12	-	27869803	PATU8988S	viability after 35 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.5418482153619205	[312]	[193,172,NaN]	6	hSpCas9	negative selection	9794627
52680224	52680247	12	-	27869803	PATU8988S	viability after 35 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	0.2795699486976422	[287]	[50,230,NaN]	3	hSpCas9	negative selection	9794628
52680246	52680269	12	+	27869803	PATU8988S	viability after 35 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	-0.2767538314332592	[544]	[261,99,NaN]	-3	hSpCas9	negative selection	9794629
52675572	52675595	12	-	27869803	PATU8988S	viability after 31 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.38401929971914683	[807]	[430,406,NaN]	5	hSpCas9	negative selection	9877073
52677715	52677738	12	-	27869803	PATU8988S	viability after 31 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	0.22870733645177288	[560]	[273,246,NaN]	3	hSpCas9	negative selection	9877074
52677718	52677741	12	-	27869803	PATU8988S	viability after 31 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.5333286568647524	[332]	[240,129,NaN]	6	hSpCas9	negative selection	9877075
52678621	52678644	12	-	27869803	PATU8988S	viability after 31 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.7478870616077349	[312]	[169,259,NaN]	8	hSpCas9	negative selection	9877076
52680224	52680247	12	-	27869803	PATU8988S	viability after 31 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	0.0395456047420325	[287]	[66,182,NaN]	0	hSpCas9	negative selection	9877077
52680246	52680269	12	+	27869803	PATU8988S	viability after 31 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	0.05682321111525143	[544]	[251,192,NaN]	0	hSpCas9	negative selection	9877078
52675572	52675595	12	-	27869803	HPAFII	viability after 35 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	0.12053521972405923	[360]	[264,123,NaN]	0	hSpCas9	negative selection	9959522
52677715	52677738	12	-	27869803	HPAFII	viability after 35 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-1.2969325315656288	[250]	[70,29,NaN]	-6	hSpCas9	negative selection	9959523
52677718	52677741	12	-	27869803	HPAFII	viability after 35 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	1.7234655206670597	[118]	[197,199,NaN]	9	hSpCas9	negative selection	9959524
52678621	52678644	12	-	27869803	HPAFII	viability after 35 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.635341959642515	[95]	[114,30,NaN]	4	hSpCas9	negative selection	9959525
52680224	52680247	12	-	27869803	HPAFII	viability after 35 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	1.2186767177483546	[81]	[145,40,NaN]	7	hSpCas9	negative selection	9959526
52680246	52680269	12	+	27869803	HPAFII	viability after 35 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	-0.3309416172534328	[252]	[106,95,NaN]	-2	hSpCas9	negative selection	9959527
52675572	52675595	12	-	27869803	HPAFII	viability after 31 days	ATCAGTGGAGGTGGCAGCCGAGG	KRT1	ENSG00000167768	-0.7711340824991728	[360]	[156,76,NaN]	-5	hSpCas9	negative selection	10041971
52677715	52677738	12	-	27869803	HPAFII	viability after 31 days	TGGTGCTTATATGACCAAGGTGG	KRT1	ENSG00000167768	-1.4186368509032423	[250]	[56,47,NaN]	-7	hSpCas9	negative selection	10041972
52677718	52677741	12	-	27869803	HPAFII	viability after 31 days	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	1.6526517327423362	[118]	[242,173,NaN]	9	hSpCas9	negative selection	10041973
52678621	52678644	12	-	27869803	HPAFII	viability after 31 days	CAACAATCTCCGAAGGAGAGTGG	KRT1	ENSG00000167768	0.7835729665571065	[95]	[153,25,NaN]	6	hSpCas9	negative selection	10041974
52680224	52680247	12	-	27869803	HPAFII	viability after 31 days	TCCACACGCCGCAGTGGAGGAGG	KRT1	ENSG00000167768	1.0017314558005248	[81]	[61,124,NaN]	7	hSpCas9	negative selection	10041975
52680246	52680269	12	+	27869803	HPAFII	viability after 31 days	AGCTGCTGGTGGTCCTGCGCTGG	KRT1	ENSG00000167768	-0.36667095443770736	[252]	[123,94,NaN]	-2	hSpCas9	negative selection	10041976
52680259	52680282	12	-	28162770	P31FUJ	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.35144670091299757	[37]	[34]	-3	hSpCas9	negative selection	10181244
52680173	52680196	12	-	28162770	P31FUJ	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.25565974668221725	[406]	[570]	2	hSpCas9	negative selection	10181245
52680235	52680258	12	+	28162770	P31FUJ	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.7547549076097343	[111]	[77]	-5	hSpCas9	negative selection	10181246
52678558	52678581	12	-	28162770	P31FUJ	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.7099729268926713	[269]	[518]	7	hSpCas9	negative selection	10181247
52677718	52677741	12	-	28162770	P31FUJ	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.22568555089786257	[555]	[763]	2	hSpCas9	negative selection	10181248
52677159	52677182	12	-	28162770	P31FUJ	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.26784915151357913	[124]	[121]	-3	hSpCas9	negative selection	10181249
52676330	52676353	12	-	28162770	P31FUJ	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-0.12970871145027507	[53]	[57]	-1	hSpCas9	negative selection	10181250
52680305	52680328	12	-	28162770	P31FUJ	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.31087208781614584	[318]	[464]	3	hSpCas9	negative selection	10181251
52680200	52680223	12	-	28162770	P31FUJ	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.10126645334519552	[283]	[357]	1	hSpCas9	negative selection	10181252
52680095	52680118	12	-	28162770	P31FUJ	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.501275110427001	[299]	[498]	5	hSpCas9	negative selection	10181253
52680259	52680282	12	-	28162770	TF1	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10350610
52680173	52680196	12	-	28162770	TF1	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	NaN	[NaN]	[339]	1	hSpCas9	negative selection	10350611
52680235	52680258	12	+	28162770	TF1	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	NaN	[NaN]	[23]	1	hSpCas9	negative selection	10350612
52678558	52678581	12	-	28162770	TF1	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	NaN	[NaN]	[135]	1	hSpCas9	negative selection	10350613
52677718	52677741	12	-	28162770	TF1	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	NaN	[NaN]	[615]	1	hSpCas9	negative selection	10350614
52677159	52677182	12	-	28162770	TF1	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10350615
52676330	52676353	12	-	28162770	TF1	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	NaN	[NaN]	[13]	1	hSpCas9	negative selection	10350616
52680305	52680328	12	-	28162770	TF1	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	NaN	[NaN]	[366]	1	hSpCas9	negative selection	10350617
52680200	52680223	12	-	28162770	TF1	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	NaN	[NaN]	[295]	1	hSpCas9	negative selection	10350618
52680095	52680118	12	-	28162770	TF1	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	NaN	[NaN]	[373]	1	hSpCas9	negative selection	10350619
52680259	52680282	12	-	28162770	SKM1	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.8220016980220057	[13]	[13]	-6	hSpCas9	negative selection	10519976
52680173	52680196	12	-	28162770	SKM1	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.13016977688737952	[91]	[177]	1	hSpCas9	negative selection	10519977
52680235	52680258	12	+	28162770	SKM1	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-1.7439991860207327	[35]	[18]	-8	hSpCas9	negative selection	10519978
52678558	52678581	12	-	28162770	SKM1	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	-0.1384753628172598	[98]	[158]	-1	hSpCas9	negative selection	10519979
52677718	52677741	12	-	28162770	SKM1	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.880557034023989	[156]	[510]	8	hSpCas9	negative selection	10519980
52677159	52677182	12	-	28162770	SKM1	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.6125483323930556	[31]	[36]	-5	hSpCas9	negative selection	10519981
52676330	52676353	12	-	28162770	SKM1	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	0.8060295245910367	[10]	[33]	7	hSpCas9	negative selection	10519982
52680305	52680328	12	-	28162770	SKM1	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.3923174227787603	[97]	[131]	-3	hSpCas9	negative selection	10519983
52680200	52680223	12	-	28162770	SKM1	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.873604866383143	[45]	[148]	8	hSpCas9	negative selection	10519984
52680095	52680118	12	-	28162770	SKM1	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.4464871379038963	[65]	[158]	4	hSpCas9	negative selection	10519985
52680259	52680282	12	-	28162770	SKM1	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.8220016980220057	[13]	[13]	-6	hSpCas9	negative selection	10689342
52680173	52680196	12	-	28162770	SKM1	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.13016977688737952	[91]	[177]	1	hSpCas9	negative selection	10689343
52680235	52680258	12	+	28162770	SKM1	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-1.7439991860207327	[35]	[18]	-8	hSpCas9	negative selection	10689344
52678558	52678581	12	-	28162770	SKM1	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	-0.1384753628172598	[98]	[158]	-1	hSpCas9	negative selection	10689345
52677718	52677741	12	-	28162770	SKM1	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.880557034023989	[156]	[510]	8	hSpCas9	negative selection	10689346
52677159	52677182	12	-	28162770	SKM1	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.6125483323930556	[31]	[36]	-5	hSpCas9	negative selection	10689347
52676330	52676353	12	-	28162770	SKM1	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	0.8060295245910367	[10]	[33]	7	hSpCas9	negative selection	10689348
52680305	52680328	12	-	28162770	SKM1	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.3923174227787603	[97]	[131]	-3	hSpCas9	negative selection	10689349
52680200	52680223	12	-	28162770	SKM1	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.873604866383143	[45]	[148]	8	hSpCas9	negative selection	10689350
52680095	52680118	12	-	28162770	SKM1	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.4464871379038963	[65]	[158]	4	hSpCas9	negative selection	10689351
52680259	52680282	12	-	28162770	PL21	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.8253954776178174	[56]	[13]	-5	hSpCas9	negative selection	10858708
52680173	52680196	12	-	28162770	PL21	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	-0.07465450480694746	[270]	[111]	0	hSpCas9	negative selection	10858709
52680235	52680258	12	+	28162770	PL21	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.9697853869529923	[107]	[23]	-6	hSpCas9	negative selection	10858710
52678558	52678581	12	-	28162770	PL21	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.11767745429734722	[323]	[152]	1	hSpCas9	negative selection	10858711
52677718	52677741	12	-	28162770	PL21	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.03263195262712704	[650]	[276]	0	hSpCas9	negative selection	10858712
52677159	52677182	12	-	28162770	PL21	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.4705527602577199	[155]	[48]	-3	hSpCas9	negative selection	10858713
52676330	52676353	12	-	28162770	PL21	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	1.6307739688191827	[45]	[61]	9	hSpCas9	negative selection	10858714
52680305	52680328	12	-	28162770	PL21	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.6389452797011135	[300]	[203]	5	hSpCas9	negative selection	10858715
52680200	52680223	12	-	28162770	PL21	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.4740010508074695	[176]	[106]	4	hSpCas9	negative selection	10858716
52680095	52680118	12	-	28162770	PL21	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.760965209328966	[220]	[162]	6	hSpCas9	negative selection	10858717
52680259	52680282	12	-	28162770	P31FUJ	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.35144670091299757	[37]	[34]	-3	hSpCas9	negative selection	11028074
52680173	52680196	12	-	28162770	P31FUJ	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.25565974668221725	[406]	[570]	2	hSpCas9	negative selection	11028075
52680235	52680258	12	+	28162770	P31FUJ	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.7547549076097343	[111]	[77]	-5	hSpCas9	negative selection	11028076
52678558	52678581	12	-	28162770	P31FUJ	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.7099729268926713	[269]	[518]	7	hSpCas9	negative selection	11028077
52677718	52677741	12	-	28162770	P31FUJ	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.22568555089786257	[555]	[763]	2	hSpCas9	negative selection	11028078
52677159	52677182	12	-	28162770	P31FUJ	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	-0.26784915151357913	[124]	[121]	-3	hSpCas9	negative selection	11028079
52676330	52676353	12	-	28162770	P31FUJ	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-0.12970871145027507	[53]	[57]	-1	hSpCas9	negative selection	11028080
52680305	52680328	12	-	28162770	P31FUJ	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.31087208781614584	[318]	[464]	3	hSpCas9	negative selection	11028081
52680200	52680223	12	-	28162770	P31FUJ	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.10126645334519552	[283]	[357]	1	hSpCas9	negative selection	11028082
52680095	52680118	12	-	28162770	P31FUJ	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.501275110427001	[299]	[498]	5	hSpCas9	negative selection	11028083
52680259	52680282	12	-	28162770	OCIAML5	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	3.3958609425795885	[6]	[132]	9	hSpCas9	negative selection	11197440
52680173	52680196	12	-	28162770	OCIAML5	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.8887513487978157	[186]	[624]	7	hSpCas9	negative selection	11197441
52680235	52680258	12	+	28162770	OCIAML5	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	0.437440046330988	[26]	[65]	4	hSpCas9	negative selection	11197442
52678558	52678581	12	-	28162770	OCIAML5	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	-0.07865898072973049	[171]	[293]	0	hSpCas9	negative selection	11197443
52677718	52677741	12	-	28162770	OCIAML5	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.4011045120227392	[317]	[757]	3	hSpCas9	negative selection	11197444
52677159	52677182	12	-	28162770	OCIAML5	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	0.3346341433291422	[75]	[172]	3	hSpCas9	negative selection	11197445
52676330	52676353	12	-	28162770	OCIAML5	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-2.437029071585153	[14]	[4]	-8	hSpCas9	negative selection	11197446
52680305	52680328	12	-	28162770	OCIAML5	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	1.208287335966952	[157]	[658]	8	hSpCas9	negative selection	11197447
52680200	52680223	12	-	28162770	OCIAML5	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	1.2242843152661178	[114]	[484]	9	hSpCas9	negative selection	11197448
52680095	52680118	12	-	28162770	OCIAML5	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	1.191693814664416	[137]	[568]	8	hSpCas9	negative selection	11197449
52680259	52680282	12	-	28162770	EOL1	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	1.024083445121449	[55]	[59]	8	hSpCas9	negative selection	11366806
52680173	52680196	12	-	28162770	EOL1	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	1.4965324182934807	[334]	[497]	9	hSpCas9	negative selection	11366807
52680235	52680258	12	+	28162770	EOL1	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	0.650040581292792	[201]	[166]	6	hSpCas9	negative selection	11366808
52678558	52678581	12	-	28162770	EOL1	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	-0.7591486827359812	[513]	[159]	-5	hSpCas9	negative selection	11366809
52677718	52677741	12	-	28162770	EOL1	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.08081740769158507	[1346]	[670]	0	hSpCas9	negative selection	11366810
52677159	52677182	12	-	28162770	EOL1	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	0.8820231549239774	[240]	[233]	7	hSpCas9	negative selection	11366811
52676330	52676353	12	-	28162770	EOL1	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-0.09591633098918129	[70]	[34]	0	hSpCas9	negative selection	11366812
52680305	52680328	12	-	28162770	EOL1	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.7358409993228618	[372]	[117]	-5	hSpCas9	negative selection	11366813
52680200	52680223	12	-	28162770	EOL1	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.6051753815869286	[281]	[225]	5	hSpCas9	negative selection	11366814
52680095	52680118	12	-	28162770	EOL1	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	1.4248863081447047	[274]	[388]	9	hSpCas9	negative selection	11366815
52680259	52680282	12	-	28162770	MOLM13	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.18922290493241278	[81]	[51]	-1	hSpCas9	negative selection	11536172
52680173	52680196	12	-	28162770	MOLM13	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.8876492910658258	[304]	[407]	6	hSpCas9	negative selection	11536173
52680235	52680258	12	+	28162770	MOLM13	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.5440832601214973	[120]	[59]	-3	hSpCas9	negative selection	11536174
52678558	52678581	12	-	28162770	MOLM13	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.8357122424025906	[395]	[510]	6	hSpCas9	negative selection	11536175
52677718	52677741	12	-	28162770	MOLM13	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.5328652132496123	[889]	[930]	4	hSpCas9	negative selection	11536176
52677159	52677182	12	-	28162770	MOLM13	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	1.1829857957501941	[225]	[370]	8	hSpCas9	negative selection	11536177
52676330	52676353	12	-	28162770	MOLM13	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-0.7995909293204071	[64]	[26]	-4	hSpCas9	negative selection	11536178
52680305	52680328	12	-	28162770	MOLM13	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.12770587694994856	[337]	[266]	0	hSpCas9	negative selection	11536179
52680200	52680223	12	-	28162770	MOLM13	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	1.274545492718629	[294]	[515]	8	hSpCas9	negative selection	11536180
52680095	52680118	12	-	28162770	MOLM13	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.20935636794572576	[255]	[213]	1	hSpCas9	negative selection	11536181
52680259	52680282	12	-	28162770	HEL	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	1.0177782633472816	[63]	[82]	8	hSpCas9	negative selection	11705538
52680173	52680196	12	-	28162770	HEL	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.21562850042093795	[319]	[237]	1	hSpCas9	negative selection	11705539
52680235	52680258	12	+	28162770	HEL	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.3842282155999124	[107]	[52]	-3	hSpCas9	negative selection	11705540
52678558	52678581	12	-	28162770	HEL	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.346345829220132	[349]	[284]	3	hSpCas9	negative selection	11705541
52677718	52677741	12	-	28162770	HEL	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.5746567092079016	[780]	[744]	5	hSpCas9	negative selection	11705542
52677159	52677182	12	-	28162770	HEL	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	0.7175928266845704	[168]	[177]	6	hSpCas9	negative selection	11705543
52676330	52676353	12	-	28162770	HEL	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-1.8536869941191418	[78]	[13]	-7	hSpCas9	negative selection	11705544
52680305	52680328	12	-	28162770	HEL	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.07474940988291429	[337]	[227]	0	hSpCas9	negative selection	11705545
52680200	52680223	12	-	28162770	HEL	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.305343935767224	[210]	[166]	2	hSpCas9	negative selection	11705546
52680095	52680118	12	-	28162770	HEL	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.2601657279680246	[248]	[190]	2	hSpCas9	negative selection	11705547
52680259	52680282	12	-	28162770	MV411	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.9504558130256435	[42]	[69]	8	hSpCas9	negative selection	11874904
52680173	52680196	12	-	28162770	MV411	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	-0.020303857728546038	[306]	[254]	0	hSpCas9	negative selection	11874905
52680235	52680258	12	+	28162770	MV411	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-1.6433333794624663	[88]	[23]	-7	hSpCas9	negative selection	11874906
52678558	52678581	12	-	28162770	MV411	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.2474375507827753	[286]	[286]	2	hSpCas9	negative selection	11874907
52677718	52677741	12	-	28162770	MV411	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.36449199753865025	[728]	[476]	-3	hSpCas9	negative selection	11874908
52677159	52677182	12	-	28162770	MV411	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	0.25971588056121186	[116]	[117]	2	hSpCas9	negative selection	11874909
52676330	52676353	12	-	28162770	MV411	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	0.48559728797753965	[38]	[45]	4	hSpCas9	negative selection	11874910
52680305	52680328	12	-	28162770	MV411	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.8021537646358112	[240]	[353]	7	hSpCas9	negative selection	11874911
52680200	52680223	12	-	28162770	MV411	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	1.6415522766977986	[190]	[501]	9	hSpCas9	negative selection	11874912
52680095	52680118	12	-	28162770	MV411	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.34697322433368993	[167]	[179]	3	hSpCas9	negative selection	11874913
52680259	52680282	12	-	28162770	MONOMAC1	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	-0.5690056244465116	[21]	[16]	-5	hSpCas9	negative selection	12044270
52680173	52680196	12	-	28162770	MONOMAC1	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.206541536844226	[157]	[208]	2	hSpCas9	negative selection	12044271
52680235	52680258	12	+	28162770	MONOMAC1	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.23656521124619134	[73]	[71]	-2	hSpCas9	negative selection	12044272
52678558	52678581	12	-	28162770	MONOMAC1	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.14176506639220487	[203]	[257]	1	hSpCas9	negative selection	12044273
52677718	52677741	12	-	28162770	MONOMAC1	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	-0.15359758579465632	[457]	[471]	-1	hSpCas9	negative selection	12044274
52677159	52677182	12	-	28162770	MONOMAC1	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	0.6790914947782778	[78]	[144]	6	hSpCas9	negative selection	12044275
52676330	52676353	12	-	28162770	MONOMAC1	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-0.10082153180025077	[28]	[30]	-1	hSpCas9	negative selection	12044276
52680305	52680328	12	-	28162770	MONOMAC1	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.2981835705164535	[191]	[178]	-3	hSpCas9	negative selection	12044277
52680200	52680223	12	-	28162770	MONOMAC1	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.3344863947001421	[109]	[158]	3	hSpCas9	negative selection	12044278
52680095	52680118	12	-	28162770	MONOMAC1	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.30086891939237914	[147]	[208]	3	hSpCas9	negative selection	12044279
52680259	52680282	12	-	28162770	OCIAML2	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	1.3107298882824983	[3]	[54]	9	hSpCas9	negative selection	12213636
52680173	52680196	12	-	28162770	OCIAML2	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	0.6752210412212936	[46]	[415]	6	hSpCas9	negative selection	12213637
52680235	52680258	12	+	28162770	OCIAML2	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-1.5961607073260198	[17]	[32]	-7	hSpCas9	negative selection	12213638
52678558	52678581	12	-	28162770	OCIAML2	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	-0.0823592355261028	[50]	[266]	0	hSpCas9	negative selection	12213639
52677718	52677741	12	-	28162770	OCIAML2	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.21365741328263876	[151]	[976]	2	hSpCas9	negative selection	12213640
52677159	52677182	12	-	28162770	OCIAML2	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	1.120331416100438	[19]	[240]	9	hSpCas9	negative selection	12213641
52676330	52676353	12	-	28162770	OCIAML2	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	0.19233518748026812	[5]	[37]	1	hSpCas9	negative selection	12213642
52680305	52680328	12	-	28162770	OCIAML2	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	0.17108745377622858	[53]	[336]	1	hSpCas9	negative selection	12213643
52680200	52680223	12	-	28162770	OCIAML2	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	0.13741628859203625	[30]	[188]	1	hSpCas9	negative selection	12213644
52680095	52680118	12	-	28162770	OCIAML2	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	1.167630901639044	[30]	[385]	9	hSpCas9	negative selection	12213645
52680259	52680282	12	-	28162770	OCIAML3	viability	GGATCATCAACTACCAGCGCAGG	KRT1	ENSG00000167768	0.6189860830100351	[10]	[50]	5	hSpCas9	negative selection	12383002
52680173	52680196	12	-	28162770	OCIAML3	viability	GGTGGTGGTAGCTTTGGTGCTGG	KRT1	ENSG00000167768	-0.44572763292183054	[96]	[214]	-3	hSpCas9	negative selection	12383003
52680235	52680258	12	+	28162770	OCIAML3	viability	GCGGCGTGTGGAGCTGCTGGTGG	KRT1	ENSG00000167768	-0.28734630209011125	[18]	[46]	-2	hSpCas9	negative selection	12383004
52678558	52678581	12	-	28162770	OCIAML3	viability	GAAGAACATGCAGGACATGGTGG	KRT1	ENSG00000167768	0.6725584564798838	[84]	[408]	6	hSpCas9	negative selection	12383005
52677718	52677741	12	-	28162770	OCIAML3	viability	GGATGGTGCTTATATGACCAAGG	KRT1	ENSG00000167768	0.4192195188478225	[189]	[766]	4	hSpCas9	negative selection	12383006
52677159	52677182	12	-	28162770	OCIAML3	viability	GAAGAGCTGCAGATCACTGCTGG	KRT1	ENSG00000167768	0.34089733145395207	[33]	[129]	3	hSpCas9	negative selection	12383007
52676330	52676353	12	-	28162770	OCIAML3	viability	GGAGCTGATGAACACAAAGCTGG	KRT1	ENSG00000167768	-0.3183731977107358	[18]	[45]	-2	hSpCas9	negative selection	12383008
52680305	52680328	12	-	28162770	OCIAML3	viability	AGGTCTGGGTACCGAAGTGGAGG	KRT1	ENSG00000167768	-0.036630971274906665	[87]	[258]	0	hSpCas9	negative selection	12383009
52680200	52680223	12	-	28162770	OCIAML3	viability	GGTGGGAGATTTTCAAGCTGTGG	KRT1	ENSG00000167768	-0.009045139603006902	[64]	[194]	0	hSpCas9	negative selection	12383010
52680095	52680118	12	-	28162770	OCIAML3	viability	ATAAGTGTGGCTAGAGGAGGTGG	KRT1	ENSG00000167768	0.9592460006696548	[45]	[269]	8	hSpCas9	negative selection	12383011