Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3868
• Symbol:KRT16
• Description:keratin 16

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT16

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41611332	41611355	17	+	26472758	Jiyoye	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	-0.013215352267177405	[359]	[268]	0	hSpCas9	negative selection	86231
41610189	41610212	17	-	26472758	Jiyoye	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	1.133313945187724	[106]	[176]	7	hSpCas9	negative selection	86232
41610955	41610978	17	-	26472758	Jiyoye	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	1.5115120413206093	[79]	[171]	8	hSpCas9	negative selection	86233
41610899	41610922	17	-	26472758	Jiyoye	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	0.6389910567289471	[108]	[127]	4	hSpCas9	negative selection	86234
41611185	41611208	17	-	26472758	Jiyoye	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	2.675664217431775	[10]	[52]	9	hSpCas9	negative selection	86235
41610888	41610911	17	-	26472758	Jiyoye	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.4955312559267203	[94]	[100]	4	hSpCas9	negative selection	86236
41611113	41611136	17	-	26472758	Jiyoye	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-0.2529746156095019	[127]	[80]	-2	hSpCas9	negative selection	86237
41612621	41612644	17	-	26472758	Jiyoye	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	1.0008550993281387	[54]	[82]	6	hSpCas9	negative selection	86238
41611441	41611464	17	+	26472758	Jiyoye	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	-0.25578963121655596	[132]	[83]	-2	hSpCas9	negative selection	86239
41611080	41611103	17	+	26472758	Jiyoye	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	1.4623169356983343	[76]	[159]	8	hSpCas9	negative selection	86240
41610383	41610406	17	+	26472758	Jiyoye	viability	GCCGCGTCTTCACATCCAGCAAG	KRT16	ENSG00000186832	-0.36475005101413277	[180]	[105]	-3	hSpCas9	negative selection	86245
41611332	41611355	17	+	26472758	KBM7	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.36597926222134003	[1271,862]	[649,625]	4	hSpCas9	negative selection	277349
41610189	41610212	17	-	26472758	KBM7	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.1844912947252192	[950,821]	[349,379]	-2	hSpCas9	negative selection	277350
41610955	41610978	17	-	26472758	KBM7	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.3196058568890397	[595,386]	[414,165]	3	hSpCas9	negative selection	277351
41610899	41610922	17	-	26472758	KBM7	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	0.45475104646042847	[593,407]	[359,280]	5	hSpCas9	negative selection	277352
41611185	41611208	17	-	26472758	KBM7	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.5191209373991063	[382,246]	[137,68]	-4	hSpCas9	negative selection	277353
41610888	41610911	17	-	26472758	KBM7	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.4755427463640965	[526,298]	[259,266]	5	hSpCas9	negative selection	277354
41611113	41611136	17	-	26472758	KBM7	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	0.43646428689240513	[507,547]	[151,505]	5	hSpCas9	negative selection	277355
41612621	41612644	17	-	26472758	KBM7	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.037298513749596945	[401,447]	[106,276]	0	hSpCas9	negative selection	277356
41611441	41611464	17	+	26472758	KBM7	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.5500374734445438	[386,390]	[311,230]	6	hSpCas9	negative selection	277357
41611080	41611103	17	+	26472758	KBM7	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.43843597261024536	[490,318]	[230,273]	5	hSpCas9	negative selection	277358
41610383	41610406	17	+	26472758	KBM7	viability	GCCGCGTCTTCACATCCAGCAAG	KRT16	ENSG00000186832	1.070971893521529	[677,462]	[641,477]	9	hSpCas9	negative selection	277363
41611332	41611355	17	+	26472758	Raji	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.48029555897976683	[416]	[134]	4	hSpCas9	negative selection	468467
41610189	41610212	17	-	26472758	Raji	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.5844306969278681	[591]	[205]	5	hSpCas9	negative selection	468468
41610955	41610978	17	-	26472758	Raji	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	1.5999820179460962	[171]	[120]	9	hSpCas9	negative selection	468469
41610899	41610922	17	-	26472758	Raji	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-1.1656349590328166	[289]	[29]	-7	hSpCas9	negative selection	468470
41611185	41611208	17	-	26472758	Raji	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.42457371125429866	[121]	[37]	4	hSpCas9	negative selection	468471
41610888	41610911	17	-	26472758	Raji	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.3544763973383719	[181]	[53]	3	hSpCas9	negative selection	468472
41611113	41611136	17	-	26472758	Raji	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-0.5240533951470575	[346]	[55]	-4	hSpCas9	negative selection	468473
41612621	41612644	17	-	26472758	Raji	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-1.2560211954899219	[246]	[23]	-7	hSpCas9	negative selection	468474
41611441	41611464	17	+	26472758	Raji	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	-0.5570134328419616	[335]	[52]	-4	hSpCas9	negative selection	468475
41611080	41611103	17	+	26472758	Raji	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.26892739602825566	[210]	[58]	2	hSpCas9	negative selection	468476
41610383	41610406	17	+	26472758	Raji	viability	GCCGCGTCTTCACATCCAGCAAG	KRT16	ENSG00000186832	1.29054756030511	[228]	[129]	9	hSpCas9	negative selection	468481
41611332	41611355	17	+	26472758	K562	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	-0.024070108259454992	[741]	[615]	0	hSpCas9	negative selection	659585
41610189	41610212	17	-	26472758	K562	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.3795150045675416	[862]	[559]	-3	hSpCas9	negative selection	659586
41610955	41610978	17	-	26472758	K562	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.5356004626587856	[312]	[382]	4	hSpCas9	negative selection	659587
41610899	41610922	17	-	26472758	K562	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-0.25633076915162406	[548]	[387]	-2	hSpCas9	negative selection	659588
41611185	41611208	17	-	26472758	K562	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.30154964143884566	[291]	[199]	-2	hSpCas9	negative selection	659589
41610888	41610911	17	-	26472758	K562	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.470769162571578	[311]	[364]	4	hSpCas9	negative selection	659590
41611113	41611136	17	-	26472758	K562	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	0.6763480063440637	[466]	[629]	5	hSpCas9	negative selection	659591
41612621	41612644	17	-	26472758	K562	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	0.4751989344956138	[293]	[344]	4	hSpCas9	negative selection	659592
41611441	41611464	17	+	26472758	K562	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.5138574586941569	[486]	[586]	4	hSpCas9	negative selection	659593
41611080	41611103	17	+	26472758	K562	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	1.0452960856528462	[286]	[499]	8	hSpCas9	negative selection	659594
41610383	41610406	17	+	26472758	K562	viability	GCCGCGTCTTCACATCCAGCAAG	KRT16	ENSG00000186832	0.8565741912781693	[472]	[722]	7	hSpCas9	negative selection	659599
41610189	41610212	17	-	26627737	DLD1	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.10470325379590084	[740]	[291,142,208]	-1	hSpCas9	negative selection	797722
41611081	41611104	17	-	26627737	DLD1	viability	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.6550083325092096	[1172]	[290,259,159]	-6	hSpCas9	negative selection	797723
41610189	41610212	17	-	26627737	GBM cells	viability after 5 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.1344447220607456	[349]	[189,151]	-2	hSpCas9	negative selection	880037
41611081	41611104	17	-	26627737	GBM cells	viability after 5 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.12064839149283224	[593]	[295,289]	-2	hSpCas9	negative selection	880038
41610189	41610212	17	-	26627737	GBM cells	viability after 13 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.24236115337661074	[349]	[265,190]	3	hSpCas9	negative selection	962352
41611081	41611104	17	-	26627737	GBM cells	viability after 13 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.5746298962395036	[593]	[195,232]	-6	hSpCas9	negative selection	962353
41610189	41610212	17	-	26627737	GBM cells	viability after 21 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.08739237413144402	[349]	[224,180]	0	hSpCas9	negative selection	1044667
41611081	41611104	17	-	26627737	GBM cells	viability after 21 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.8552937352481167	[593]	[192,164]	-6	hSpCas9	negative selection	1044668
41610189	41610212	17	-	26627737	RPE1	viability after 9 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-1.783091784432859	[2182]	[236,148]	-8	hSpCas9	negative selection	1126982
41611081	41611104	17	-	26627737	RPE1	viability after 9 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	1.2047406133233702	[865]	[675,558]	7	hSpCas9	negative selection	1126983
41610189	41610212	17	-	26627737	RPE1	viability after 12 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-2.176156029555732	[2182]	[121,137]	-8	hSpCas9	negative selection	1209297
41611081	41611104	17	-	26627737	RPE1	viability after 12 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	1.384527014421426	[865]	[622,590]	7	hSpCas9	negative selection	1209298
41610189	41610212	17	-	26627737	RPE1	viability after 15 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-1.5002330491261298	[2182]	[229,206]	-7	hSpCas9	negative selection	1291612
41611081	41611104	17	-	26627737	RPE1	viability after 15 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	1.0855921469298881	[865]	[525,513]	6	hSpCas9	negative selection	1291613
41610189	41610212	17	-	26627737	RPE1	viability after 18 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-2.0010358531386907	[2182]	[93,203]	-8	hSpCas9	negative selection	1373927
41611081	41611104	17	-	26627737	RPE1	viability after 18 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	1.0788984865355515	[865]	[469,518]	6	hSpCas9	negative selection	1373928
41610189	41610212	17	-	26627737	HeLa	viability after 8 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.23026560857806438	[303]	[140,189,132]	2	hSpCas9	negative selection	1456242
41611081	41611104	17	-	26627737	HeLa	viability after 8 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.3416132247976631	[938]	[476,344,188]	-3	hSpCas9	negative selection	1456243
41610189	41610212	17	-	26627737	HeLa	viability after 12 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.1785247274140533	[303]	[114,120,191]	1	hSpCas9	negative selection	1538557
41611081	41611104	17	-	26627737	HeLa	viability after 12 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.059856933276699165	[938]	[364,434,309]	0	hSpCas9	negative selection	1538558
41610189	41610212	17	-	26627737	HeLa	viability after 15 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.3227451648258305	[303]	[102,176,9]	-3	hSpCas9	negative selection	1620872
41611081	41611104	17	-	26627737	HeLa	viability after 15 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.3906611129344275	[938]	[370,207,294]	-3	hSpCas9	negative selection	1620873
41610189	41610212	17	-	26627737	HeLa	viability after 18 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.3774214530856056	[303]	[59,148,9]	-3	hSpCas9	negative selection	1703187
41611081	41611104	17	-	26627737	HeLa	viability after 18 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.4104132675889025	[938]	[238,174,294]	-4	hSpCas9	negative selection	1703188
41610189	41610212	17	-	26627737	HCT116	viability after 6 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.5465011627712382	[1859]	[448,62]	-3	hSpCas9	negative selection	1785502
41611081	41611104	17	-	26627737	HCT116	viability after 6 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.7158911858513723	[1361]	[237,70]	-4	hSpCas9	negative selection	1785503
41610189	41610212	17	-	26627737	HCT116	viability after 8 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.5539674960575841	[504]	[143,249,173]	-6	hSpCas9	negative selection	1867817
41611081	41611104	17	-	26627737	HCT116	viability after 8 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	0.04353783928281629	[698]	[289,419,477]	0	hSpCas9	negative selection	1867818
41610189	41610212	17	-	26627737	HCT116	viability after 9 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.8760118233885876	[1859]	[383,180]	-6	hSpCas9	negative selection	1950132
41611081	41611104	17	-	26627737	HCT116	viability after 9 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	0.508278415599706	[1361]	[733,345]	4	hSpCas9	negative selection	1950133
41610189	41610212	17	-	26627737	HCT116	viability after 12 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.8470023515400137	[504]	[76,154,216]	-7	hSpCas9	negative selection	2032447
41611081	41611104	17	-	26627737	HCT116	viability after 12 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.07587499842500112	[698]	[319,427,301]	0	hSpCas9	negative selection	2032448
41610189	41610212	17	-	26627737	HCT116	viability after 15 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.1983895646018099	[504]	[141,200,399]	-2	hSpCas9	negative selection	2114762
41611081	41611104	17	-	26627737	HCT116	viability after 15 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	0.6941999060823285	[698]	[756,586,617]	6	hSpCas9	negative selection	2114763
41610189	41610212	17	-	26627737	HCT116	viability after 18 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.7894227446959385	[504]	[101,103,223]	-6	hSpCas9	negative selection	2197077
41611081	41611104	17	-	26627737	HCT116	viability after 18 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	0.6755683277229598	[698]	[508,528,583]	5	hSpCas9	negative selection	2197078
41612960	41612983	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCATTTCTGTGTTTTTCTCTCGG	KRT16	ENSG00000186832	0.11559158390193591	[968,378]	[276,32]	0	dCas9-VP64	positive selection	2438273
41612922	41612945	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCTGGGTGGGAACTCTGAGCCGG	KRT16	ENSG00000186832	4.6323908561821465	[5,4]	[7,60]	9	dCas9-VP64	positive selection	2438276
41612985	41613008	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTTCGGTGGTGACTCAGGCTAGG	KRT16	ENSG00000186832	0.7857945552892892	[7,73]	[4,25]	3	dCas9-VP64	positive selection	2438277
41612960	41612983	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCATTTCTGTGTTTTTCTCTCGG	KRT16	ENSG00000186832	-0.47388105723949847	[498,604]	[128,129]	-5	dCas9-VP64	positive selection	2533528
41612922	41612945	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCTGGGTGGGAACTCTGAGCCGG	KRT16	ENSG00000186832	3.6410312692817572	[45,20]	[281,5]	9	dCas9-VP64	positive selection	2533531
41612985	41613008	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTTCGGTGGTGACTCAGGCTAGG	KRT16	ENSG00000186832	-1.1244788161987735	[128,143]	[32,7]	-9	dCas9-VP64	positive selection	2533532
41611687	41611710	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATGGGCTGCGCATTCTCAATGG	KRT16	ENSG00000186832	-0.9927252742159103	[2,2]	[0,1]	-9	hSpCas9	positive selection	2998125
41611712	41611735	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATCCCCACTCCAGATCATTGCGG	KRT16	ENSG00000186832	0.07994712196390302	[3,4]	[3,3]	1	hSpCas9	positive selection	2998126
41611423	41611446	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGGTCAGCTCATCCAACACCCGG	KRT16	ENSG00000186832	-0.05171274205235174	[3,3]	[4,1]	0	hSpCas9	positive selection	2998127
41611636	41611659	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCACTTGGTCCTGAAGTCATCGG	KRT16	ENSG00000186832	-0.4843306308928472	[4,3]	[3,0]	-6	hSpCas9	positive selection	2998128
41611687	41611710	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATGGGCTGCGCATTCTCAATGG	KRT16	ENSG00000186832	-0.3122590745093175	[2,2]	[2,0]	-5	hSpCas9	positive selection	3065983
41611712	41611735	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATCCCCACTCCAGATCATTGCGG	KRT16	ENSG00000186832	-0.14998816236355367	[3,3]	[2,1]	-2	hSpCas9	positive selection	3065984
41611423	41611446	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGGTCAGCTCATCCAACACCCGG	KRT16	ENSG00000186832	-0.3570245010822284	[3,3]	[3,0]	-5	hSpCas9	positive selection	3065985
41611636	41611659	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCACTTGGTCCTGAAGTCATCGG	KRT16	ENSG00000186832	-0.251123972562457	[4,4]	[2,1]	-4	hSpCas9	positive selection	3065986
41611451	41611474		-	24336571	A375	resistance to PLX after 7 days	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.05358053401437329	[12,8]	[10,10]	-1	hSpCas9	positive selection	3123726
41611485	41611508		-	24336571	A375	resistance to PLX after 7 days	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.2108377980383862	[14,17]	[16,20]	6	hSpCas9	positive selection	3123727
41611451	41611474		-	24336571	A375	resistance to PLX after 14 days	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.3280714028453552	[11,10]	[4,3]	-4	hSpCas9	positive selection	3181519
41611485	41611508		-	24336571	A375	resistance to PLX after 14 days	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.09861895129503484	[18,17]	[7,9]	1	hSpCas9	positive selection	3181520
41611451	41611474		-	24336571	A375	viability after 7 days	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.5523079893379061	[7]	[12,8]	8	hSpCas9	negative selection	3239312
41611485	41611508		-	24336571	A375	viability after 7 days	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.01869231019928469	[16]	[14,17]	0	hSpCas9	negative selection	3239313
41611451	41611474		-	24336571	A375	viability after 14 days	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.6316418289461447	[7]	[11,10]	7	hSpCas9	negative selection	3297105
41611485	41611508		-	24336571	A375	viability after 14 days	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.1826164639994861	[16]	[18,17]	2	hSpCas9	negative selection	3297106
41611451	41611474	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.7256673632484749	[252,252]	[0,0]	-5	hSpCas9	positive selection	3376249
41610929	41610952	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	1.7337642553888224	[45,45]	[0,0]	7	hSpCas9	positive selection	3376250
41610844	41610867	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	1.529405756882636	[52,52]	[0,0]	6	hSpCas9	positive selection	3376251
41611686	41611709	17	+	26780180	HT29	viability (Avana library 4 designs)	AATGGGCTGCGCATTCTCAATGG	KRT16	ENSG00000186832	3.28894915051605	[]	[]	8	hSpCas9	negative selection	3435577
41611712	41611735	17	-	26780180	HT29	viability (Avana library 4 designs)	ATCCCCACTCCAGATCATTGCGG	KRT16	ENSG00000186832	2.54996510245243	[]	[]	8	hSpCas9	negative selection	3435578
41611422	41611445	17	+	26780180	HT29	viability (Avana library 4 designs)	GGGTCAGCTCATCCAACACCCGG	KRT16	ENSG00000186832	1.03026213149191	[]	[]	4	hSpCas9	negative selection	3435579
41611635	41611658	17	+	26780180	HT29	viability (Avana library 4 designs)	TCACTTGGTCCTGAAGTCATCGG	KRT16	ENSG00000186832	2.60815330489918	[]	[]	8	hSpCas9	negative selection	3435580
41611635	41611658	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCACTTGGTCCTGAAGTCATCGG	KRT16	ENSG00000186832	-0.905402748280902	[]	[]	-1	hSpCas9	negative selection	3523213
41611686	41611709	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	AATGGGCTGCGCATTCTCAATGG	KRT16	ENSG00000186832	-4.49471457407288	[]	[]	-5	hSpCas9	negative selection	3523214
41611712	41611735	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATCCCCACTCCAGATCATTGCGG	KRT16	ENSG00000186832	-3.57334950290917	[]	[]	-4	hSpCas9	negative selection	3523215
41611422	41611445	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGGTCAGCTCATCCAACACCCGG	KRT16	ENSG00000186832	-1.33390722520353	[]	[]	-2	hSpCas9	negative selection	3523216
41612509	41612532	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCCCCCAGAGGAGAAGCGAGAGG	KRT16	ENSG00000186832	1.58270155117754	[]	[]	2	hSpCas9	negative selection	3523217
41611477	41611500	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATGAGCATGAACTGGCCCTGCGG	KRT16	ENSG00000186832	4.67409562442559	[]	[]	7	hSpCas9	negative selection	3523218
41611635	41611658	17	+	26780180	A375	viability (Avana lentiGuide)	TCACTTGGTCCTGAAGTCATCGG	KRT16	ENSG00000186832	5.78304713588383	[]	[]	5	hSpCas9	negative selection	3631872
41611686	41611709	17	+	26780180	A375	viability (Avana lentiGuide)	AATGGGCTGCGCATTCTCAATGG	KRT16	ENSG00000186832	10.276776623295	[]	[]	7	hSpCas9	negative selection	3631873
41611712	41611735	17	-	26780180	A375	viability (Avana lentiGuide)	ATCCCCACTCCAGATCATTGCGG	KRT16	ENSG00000186832	4.5765753146979	[]	[]	4	hSpCas9	negative selection	3631874
41611422	41611445	17	+	26780180	A375	viability (Avana lentiGuide)	GGGTCAGCTCATCCAACACCCGG	KRT16	ENSG00000186832	2.73916544456913	[]	[]	3	hSpCas9	negative selection	3631875
41612509	41612532	17	+	26780180	A375	viability (Avana lentiGuide)	TCCCCCAGAGGAGAAGCGAGAGG	KRT16	ENSG00000186832	6.5517157738392	[]	[]	5	hSpCas9	negative selection	3631876
41611477	41611500	17	-	26780180	A375	viability (Avana lentiGuide)	ATGAGCATGAACTGGCCCTGCGG	KRT16	ENSG00000186832	-2.18481092051477	[]	[]	-4	hSpCas9	negative selection	3631877
41611635	41611658	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCACTTGGTCCTGAAGTCATCGG	KRT16	ENSG00000186832	-0.21305366137212922	[5]	[5,3]	-3	hSpCas9	positive selection	3740531
41611686	41611709	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATGGGCTGCGCATTCTCAATGG	KRT16	ENSG00000186832	-0.6943428068117907	[5]	[4,1]	-7	hSpCas9	positive selection	3740532
41611712	41611735	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATCCCCACTCCAGATCATTGCGG	KRT16	ENSG00000186832	-0.3563642794008473	[7]	[6,4]	-5	hSpCas9	positive selection	3740533
41611422	41611445	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGGTCAGCTCATCCAACACCCGG	KRT16	ENSG00000186832	-0.3896871441602827	[4]	[4,1]	-5	hSpCas9	positive selection	3740534
41612509	41612532	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCCCCAGAGGAGAAGCGAGAGG	KRT16	ENSG00000186832	0.21653684138241072	[4]	[4,4]	6	hSpCas9	positive selection	3740535
41611477	41611500	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATGAGCATGAACTGGCCCTGCGG	KRT16	ENSG00000186832	0.3829330882928368	[5]	[6,7]	9	hSpCas9	positive selection	3740536
41611635	41611658	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCACTTGGTCCTGAAGTCATCGG	KRT16	ENSG00000186832	0.05960465534003401	[6]	[5,5]	1	hSpCas9	positive selection	3849138
41611686	41611709	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATGGGCTGCGCATTCTCAATGG	KRT16	ENSG00000186832	-0.7310823561592132	[5]	[1,2]	-7	hSpCas9	positive selection	3849139
41611712	41611735	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATCCCCACTCCAGATCATTGCGG	KRT16	ENSG00000186832	-0.01464194562648291	[6]	[6,4]	0	hSpCas9	positive selection	3849140
41611422	41611445	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGGTCAGCTCATCCAACACCCGG	KRT16	ENSG00000186832	0.04026443047937743	[5]	[4,4]	0	hSpCas9	positive selection	3849141
41612509	41612532	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCCCCAGAGGAGAAGCGAGAGG	KRT16	ENSG00000186832	-0.1895517566138162	[4]	[2,4]	-3	hSpCas9	positive selection	3849142
41611477	41611500	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATGAGCATGAACTGGCCCTGCGG	KRT16	ENSG00000186832	-0.040860836605945035	[5]	[5,3]	0	hSpCas9	positive selection	3849143
41611451	41611474	17	-	26780180	A375	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.449176211060111	[]	[]	1	hSpCas9	negative selection	3955223
41611183	41611206	17	+	26780180	A375	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	1.12694201213201	[]	[]	5	hSpCas9	negative selection	3955224
41611185	41611208	17	-	26780180	A375	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.165894012020726	[]	[]	0	hSpCas9	negative selection	3955225
41610929	41610952	17	+	26780180	A375	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	1.51121412321068	[]	[]	8	hSpCas9	negative selection	3955226
41610844	41610867	17	+	26780180	A375	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.69682627051408	[]	[]	2	hSpCas9	negative selection	3955227
41611485	41611508	17	-	26780180	A375	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.0888047842604684	[]	[]	0	hSpCas9	negative selection	3955228
41611451	41611474	17	-	26780180	HT29	viability (GeCKOv2 library)	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.636422157304432	[]	[]	2	hSpCas9	negative selection	4063189
41611183	41611206	17	+	26780180	HT29	viability (GeCKOv2 library)	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	1.6153838331137	[]	[]	8	hSpCas9	negative selection	4063190
41611185	41611208	17	-	26780180	HT29	viability (GeCKOv2 library)	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.0991730894304185	[]	[]	0	hSpCas9	negative selection	4063191
41610929	41610952	17	+	26780180	HT29	viability (GeCKOv2 library)	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	1.97142779259511	[]	[]	9	hSpCas9	negative selection	4063192
41610844	41610867	17	+	26780180	HT29	viability (GeCKOv2 library)	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.776694391740427	[]	[]	3	hSpCas9	negative selection	4063193
41611485	41611508	17	-	26780180	HT29	viability (GeCKOv2 library)	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.142162107341979	[]	[]	0	hSpCas9	negative selection	4063194
41611451	41611474	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.14156721397867053	[3]	[1,1]	-3	hSpCas9	positive selection	4147689
41611485	41611508	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.432534515952186	[3]	[3,3]	8	hSpCas9	positive selection	4147690
41611451	41611474	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.5949739657862956	[3]	[1,0,0,3]	4	hSpCas9	positive selection	4211711
41611485	41611508	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.7825804361799815	[4]	[4,0,1,3]	5	hSpCas9	positive selection	4211712
41611183	41611206	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-1.1093325733190529	[2]	[0,0]	-9	hSpCas9	positive selection	4279107
41611185	41611208	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.4333315090595621	[2]	[2,2]	8	hSpCas9	positive selection	4279108
41611485	41611508	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.07138980700472897	[0]	[0,0]	1	hSpCas9	positive selection	4279109
41611451	41611474	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.14989945473300256	[3]	[3,2]	3	hSpCas9	positive selection	4343362
41610929	41610952	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.4113744692604246	[2]	[0,0]	-7	hSpCas9	positive selection	4343363
41610844	41610867	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.5789379405463102	[2]	[2,2]	9	hSpCas9	positive selection	4343364
41611333	41611355	17	+	27760321	OCIAML3	viability	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.04354371962057546	[1164,864]	[694,961]	0	hSpCas9	negative selection	4413064
41611442	41611464	17	+	27760321	OCIAML3	viability	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.6306673481637017	[656,602]	[753,773]	7	hSpCas9	negative selection	4413065
41611484	41611506	17	+	27760321	OCIAML3	viability	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.6429214874451308	[626,454]	[467,896]	7	hSpCas9	negative selection	4413066
41612534	41612556	17	+	27760321	OCIAML3	viability	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.17151220300088343	[986,791]	[522,732]	-2	hSpCas9	negative selection	4413067
41611333	41611355	17	+	27760321	OCIAML2	viability	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.10972675819022171	[1164,864]	[752,1042]	1	hSpCas9	negative selection	4496527
41611442	41611464	17	+	27760321	OCIAML2	viability	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.4205770578742697	[656,602]	[621,760]	6	hSpCas9	negative selection	4496528
41611484	41611506	17	+	27760321	OCIAML2	viability	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.2733899879433332	[626,454]	[386,703]	3	hSpCas9	negative selection	4496529
41612534	41612556	17	+	27760321	OCIAML2	viability	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.2638622223360283	[986,791]	[509,708]	-3	hSpCas9	negative selection	4496530
41611333	41611355	17	+	27760321	MV411	viability	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.08251032179002649	[1164,864]	[399,1157]	0	hSpCas9	negative selection	4579990
41611442	41611464	17	+	27760321	MV411	viability	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.31752870180057924	[656,602]	[479,574]	2	hSpCas9	negative selection	4579991
41611484	41611506	17	+	27760321	MV411	viability	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	1.5063589791124363	[626,454]	[1152,780]	9	hSpCas9	negative selection	4579992
41612534	41612556	17	+	27760321	MV411	viability	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.15968920332669112	[986,791]	[611,387]	-1	hSpCas9	negative selection	4579993
41611333	41611355	17	+	27760321	HL60	viability	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.13673555665445836	[1164,864]	[604,1219]	1	hSpCas9	negative selection	4663453
41611442	41611464	17	+	27760321	HL60	viability	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.31820112225631536	[656,602]	[557,729]	4	hSpCas9	negative selection	4663454
41611484	41611506	17	+	27760321	HL60	viability	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	-0.4801487081158024	[626,454]	[370,252]	-5	hSpCas9	negative selection	4663455
41612534	41612556	17	+	27760321	HL60	viability	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.08840589954988365	[986,791]	[646,713]	-1	hSpCas9	negative selection	4663456
41611333	41611355	17	+	27760321	HT1080	viability	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.5029932154667007	[864,674]	[459,406]	2	hSpCas9	negative selection	4746916
41611442	41611464	17	+	27760321	HT1080	viability	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	-0.26135169464126484	[602,470]	[114,247]	-1	hSpCas9	negative selection	4746917
41611484	41611506	17	+	27760321	HT1080	viability	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	1.576659964201867	[454,354]	[443,521]	8	hSpCas9	negative selection	4746918
41612534	41612556	17	+	27760321	HT1080	viability	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.9200528773585954	[791,617]	[188,103]	-4	hSpCas9	negative selection	4746919
41611333	41611355	17	+	27760321	HT29	viability after 7 days	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.41645925017129737	[864,674]	[1390,1453,1132]	6	hSpCas9	negative selection	4830379
41611442	41611464	17	+	27760321	HT29	viability after 7 days	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.08485242967730178	[602,470]	[738,732,724]	1	hSpCas9	negative selection	4830380
41611484	41611506	17	+	27760321	HT29	viability after 7 days	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.16471930686048006	[454,354]	[607,667,480]	2	hSpCas9	negative selection	4830381
41612534	41612556	17	+	27760321	HT29	viability after 7 days	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.04964487985959165	[791,617]	[949,696,985]	0	hSpCas9	negative selection	4830382
41611333	41611355	17	+	27760321	HT29	viability after 25 days	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.9385028869567353	[864,674]	[2220,979,1837]	9	hSpCas9	negative selection	4913842
41611442	41611464	17	+	27760321	HT29	viability after 25 days	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.0961956222210969	[602,470]	[567,676,735]	1	hSpCas9	negative selection	4913843
41611484	41611506	17	+	27760321	HT29	viability after 25 days	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.5863445042989601	[454,354]	[754,792,512]	6	hSpCas9	negative selection	4913844
41612534	41612556	17	+	27760321	HT29	viability after 25 days	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.12264905571328943	[791,617]	[612,700,932]	-1	hSpCas9	negative selection	4913845
41611333	41611355	17	+	27760321	HT29	viability after 22 days	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.45384564294087437	[864,674]	[1411,1064,1174]	5	hSpCas9	negative selection	4997305
41611442	41611464	17	+	27760321	HT29	viability after 22 days	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	-0.26783506897566184	[602,470]	[394,655,498]	-3	hSpCas9	negative selection	4997306
41611484	41611506	17	+	27760321	HT29	viability after 22 days	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.7913908746011862	[454,354]	[629,1182,620]	8	hSpCas9	negative selection	4997307
41612534	41612556	17	+	27760321	HT29	viability after 22 days	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.11036400252453571	[791,617]	[829,561,871]	-1	hSpCas9	negative selection	4997308
41611333	41611355	17	+	27760321	HT29	viability after 19 days	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.36294560713087454	[864,674]	[1658,769,1026]	3	hSpCas9	negative selection	5080768
41611442	41611464	17	+	27760321	HT29	viability after 19 days	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.2744001956349258	[602,470]	[773,598,853]	2	hSpCas9	negative selection	5080769
41611484	41611506	17	+	27760321	HT29	viability after 19 days	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.3240999531253751	[454,354]	[966,589,235]	3	hSpCas9	negative selection	5080770
41612534	41612556	17	+	27760321	HT29	viability after 19 days	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	0.10088733673984207	[791,617]	[876,698,1012]	0	hSpCas9	negative selection	5080771
41611333	41611355	17	+	27760321	HT29	viability after 16 days	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.4313559945549368	[864,674]	[1534,784,1209]	5	hSpCas9	negative selection	5164231
41611442	41611464	17	+	27760321	HT29	viability after 16 days	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.03783945339055017	[602,470]	[592,579,675]	0	hSpCas9	negative selection	5164232
41611484	41611506	17	+	27760321	HT29	viability after 16 days	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.6412004349531225	[454,354]	[800,546,784]	7	hSpCas9	negative selection	5164233
41612534	41612556	17	+	27760321	HT29	viability after 16 days	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.2302126087986256	[791,617]	[457,820,713]	-3	hSpCas9	negative selection	5164234
41611333	41611355	17	+	27760321	HT29	viability after 13 days	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.4333406849115078	[864,674]	[1261,1092,1259]	5	hSpCas9	negative selection	5247694
41611442	41611464	17	+	27760321	HT29	viability after 13 days	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	-0.028456483488339512	[602,470]	[583,765,489]	0	hSpCas9	negative selection	5247695
41611484	41611506	17	+	27760321	HT29	viability after 13 days	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.8122774297398276	[454,354]	[1042,701,734]	9	hSpCas9	negative selection	5247696
41612534	41612556	17	+	27760321	HT29	viability after 13 days	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	-0.007823180340132074	[791,617]	[686,897,852]	0	hSpCas9	negative selection	5247697
41611333	41611355	17	+	27760321	HT29	viability after 10 days	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.4461418502543111	[864,674]	[1727,1340,870]	6	hSpCas9	negative selection	5331157
41611442	41611464	17	+	27760321	HT29	viability after 10 days	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.06693981726517362	[602,470]	[480,982,651]	0	hSpCas9	negative selection	5331158
41611484	41611506	17	+	27760321	HT29	viability after 10 days	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	0.593156400798137	[454,354]	[767,834,688]	7	hSpCas9	negative selection	5331159
41612534	41612556	17	+	27760321	HT29	viability after 10 days	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	0.0419888938717915	[791,617]	[636,675,1387]	0	hSpCas9	negative selection	5331160
41611333	41611355	17	+	27760321	MOLM13	viability	CAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	-0.4827944679318521	[1164,864]	[329,470]	-3	hSpCas9	negative selection	5414620
41611442	41611464	17	+	27760321	MOLM13	viability	CGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	1.3103727893617854	[656,602]	[1515,340]	8	hSpCas9	negative selection	5414621
41611484	41611506	17	+	27760321	MOLM13	viability	GCCAGTTCATGCTCATACCTGG	KRT16	ENSG00000186832	1.0843667041391123	[626,454]	[769,530]	7	hSpCas9	negative selection	5414622
41612534	41612556	17	+	27760321	MOLM13	viability	ACAGACAGGCCGCCCCCGTAGG	KRT16	ENSG00000186832	0.6113725051995529	[986,791]	[885,656]	4	hSpCas9	negative selection	5414623
41612713	41612736	17	+	27661255	K562	viability	GTGAGCAGTTGGCTGAAAGAAGG	KRT16	ENSG00000186832	-0.07078377271156322	[1234,1404]	[1121,898]	-3	dCas9-KRAB	negative selection	5489235
41612747	41612770	17	+	27661255	K562	viability	GGAAGGCTGAGAGCGTGCTGTGG	KRT16	ENSG00000186832	0.07785214537721097	[1272,1301]	[1104,1067]	2	dCas9-KRAB	negative selection	5489236
41612513	41612536	17	-	27661255	K562	viability	GTCTCCTCTCGCTTCTCCTCTGG	KRT16	ENSG00000186832	0.014550002908210513	[1020,1273]	[979,872]	0	dCas9-KRAB	negative selection	5489237
41612621	41612644	17	-	27661255	K562	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.15877557088712835	[869,1000]	[691,646]	-5	dCas9-KRAB	negative selection	5489238
41611183	41611206	17	+	27260156	BXPC3	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.06583153389094532	[232]	[216,332,185,283]	1	hSpCas9	negative selection	5551567
41611185	41611208	17	-	27260156	BXPC3	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.44239251643913635	[305]	[413,482,441,390]	8	hSpCas9	negative selection	5551568
41611485	41611508	17	-	27260156	BXPC3	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.4326095560293437	[11]	[1,7,0,7]	-9	hSpCas9	negative selection	5551569
41611451	41611474	17	-	27260156	BXPC3	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.16096699530521774	[691]	[760,801,836,839]	3	hSpCas9	negative selection	5615822
41610929	41610952	17	+	27260156	BXPC3	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.31500654405222295	[225]	[181,232,175,161]	-6	hSpCas9	negative selection	5615823
41610844	41610867	17	+	27260156	BXPC3	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.4618575890111176	[233]	[259,319,388,393]	8	hSpCas9	negative selection	5615824
41611183	41611206	17	+	27260156	A673	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.11455039170359327	[232]	[322,224,288,200]	-3	hSpCas9	negative selection	5672818
41611185	41611208	17	-	27260156	A673	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.5683951202558724	[305]	[586,462,558,577]	9	hSpCas9	negative selection	5672819
41611485	41611508	17	-	27260156	A673	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.1409735126298397	[11]	[7,12,11,18]	-4	hSpCas9	negative selection	5672820
41611451	41611474	17	-	27260156	A673	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.11250573974436118	[691]	[1005,885,812,899]	2	hSpCas9	negative selection	5737073
41610929	41610952	17	+	27260156	A673	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.16027357058439362	[225]	[167,247,251,296]	-4	hSpCas9	negative selection	5737074
41610844	41610867	17	+	27260156	A673	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.4385218139760384	[233]	[453,273,397,408]	8	hSpCas9	negative selection	5737075
41611183	41611206	17	+	27260156	A375	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.20314554789145145	[232]	[340,366,204,342]	3	hSpCas9	negative selection	5794069
41611185	41611208	17	-	27260156	A375	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.8048097699982395	[305]	[496,1068,532,474]	9	hSpCas9	negative selection	5794070
41611485	41611508	17	-	27260156	A375	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-2.4496532202749233	[11]	[4,0,0,2]	-9	hSpCas9	negative selection	5794071
41611451	41611474	17	-	27260156	A375	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.17574775186531177	[691]	[779,925,1176,781]	2	hSpCas9	negative selection	5858324
41610929	41610952	17	+	27260156	A375	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.5975885007037811	[225]	[207,189,260,54]	-7	hSpCas9	negative selection	5858325
41610844	41610867	17	+	27260156	A375	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.4969098603293266	[233]	[300,362,353,504]	7	hSpCas9	negative selection	5858326
41611183	41611206	17	+	27260156	COLO741	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.1377787644049665	[232]	[408,340,244]	3	hSpCas9	negative selection	5915320
41611185	41611208	17	-	27260156	COLO741	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.5826103013456236	[305]	[441,696,602]	9	hSpCas9	negative selection	5915321
41611485	41611508	17	-	27260156	COLO741	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.505734940362629	[11]	[12,0,2]	-9	hSpCas9	negative selection	5915322
41611451	41611474	17	-	27260156	COLO741	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.06919753117404648	[691]	[1076,967,760]	1	hSpCas9	negative selection	5979575
41610929	41610952	17	+	27260156	COLO741	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.19093368053137683	[225]	[253,175,322]	-4	hSpCas9	negative selection	5979576
41610844	41610867	17	+	27260156	COLO741	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.38022524434163063	[233]	[410,418,341]	7	hSpCas9	negative selection	5979577
41611183	41611206	17	+	27260156	CAL120	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.29346215846377566	[232]	[286,490,278]	4	hSpCas9	negative selection	6036571
41611185	41611208	17	-	27260156	CAL120	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.6695820963575585	[305]	[699,470,658]	8	hSpCas9	negative selection	6036572
41611485	41611508	17	-	27260156	CAL120	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-3.468614620979423	[11]	[0,1,0]	-9	hSpCas9	negative selection	6036573
41611451	41611474	17	-	27260156	CAL120	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.13032147974001512	[691]	[629,1069,638]	-2	hSpCas9	negative selection	6100826
41610929	41610952	17	+	27260156	CAL120	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.15971322870425864	[225]	[435,156,190]	-2	hSpCas9	negative selection	6100827
41610844	41610867	17	+	27260156	CAL120	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.05904537935379339	[233]	[344,256,313]	0	hSpCas9	negative selection	6100828
41611183	41611206	17	+	27260156	CADOES1	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.16167637966463821	[232]	[299,199,261,205]	2	hSpCas9	negative selection	6157822
41611185	41611208	17	-	27260156	CADOES1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.5545497973896669	[305]	[460,518,403,282]	8	hSpCas9	negative selection	6157823
41611485	41611508	17	-	27260156	CADOES1	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.15430434909796453	[11]	[14,14,2,6]	-3	hSpCas9	negative selection	6157824
41611451	41611474	17	-	27260156	CADOES1	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.06628732733404752	[691]	[570,667,697,761]	1	hSpCas9	negative selection	6222077
41610929	41610952	17	+	27260156	CADOES1	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-1.1122815567237045	[225]	[62,130,124,68]	-9	hSpCas9	negative selection	6222078
41610844	41610867	17	+	27260156	CADOES1	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.5379362809490091	[233]	[331,307,329,292]	8	hSpCas9	negative selection	6222079
41611183	41611206	17	+	27260156	EWS502	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.01847740077013893	[232]	[289,131,250,303]	0	hSpCas9	negative selection	6279073
41611185	41611208	17	-	27260156	EWS502	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.574175448201761	[305]	[462,503,411,554]	8	hSpCas9	negative selection	6279074
41611485	41611508	17	-	27260156	EWS502	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.7216948888213972	[11]	[53,21,0,0]	9	hSpCas9	negative selection	6279075
41611451	41611474	17	-	27260156	EWS502	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.23499288383820693	[691]	[913,934,707,879]	4	hSpCas9	negative selection	6343328
41610929	41610952	17	+	27260156	EWS502	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.5388322251995041	[225]	[189,139,182,141]	-7	hSpCas9	negative selection	6343329
41610844	41610867	17	+	27260156	EWS502	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.5936062569054538	[233]	[403,221,335,546]	8	hSpCas9	negative selection	6343330
41611183	41611206	17	+	27260156	EW8	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.24896828466882992	[232]	[116,66,114,337]	-5	hSpCas9	negative selection	6400324
41611185	41611208	17	-	27260156	EW8	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.5031564301430264	[305]	[453,304,351,304]	8	hSpCas9	negative selection	6400325
41611485	41611508	17	-	27260156	EW8	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	1.5868412545304862	[11]	[10,18,44,36]	9	hSpCas9	negative selection	6400326
41611451	41611474	17	-	27260156	EW8	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.14544144986797758	[691]	[702,653,625,504]	2	hSpCas9	negative selection	6464579
41610929	41610952	17	+	27260156	EW8	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.6102624641318228	[225]	[85,154,65,177]	-8	hSpCas9	negative selection	6464580
41610844	41610867	17	+	27260156	EW8	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.4772560950742175	[233]	[466,140,192,287]	8	hSpCas9	negative selection	6464581
41611183	41611206	17	+	27260156	CORL105	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.3567575501610196	[232]	[228,195,238,192]	-6	hSpCas9	negative selection	6521575
41611185	41611208	17	-	27260156	CORL105	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.6833404258380524	[305]	[745,474,512,564]	9	hSpCas9	negative selection	6521576
41611485	41611508	17	-	27260156	CORL105	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.66151104014864	[11]	[1,11,0,1]	-9	hSpCas9	negative selection	6521577
41611451	41611474	17	-	27260156	CORL105	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.339046929349783	[691]	[457,664,826,633]	-6	hSpCas9	negative selection	6585830
41610929	41610952	17	+	27260156	CORL105	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.7677469550116081	[225]	[245,60,189,134]	-8	hSpCas9	negative selection	6585831
41610844	41610867	17	+	27260156	CORL105	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.35825455486537783	[233]	[316,226,437,436]	6	hSpCas9	negative selection	6585832
41611183	41611206	17	+	27260156	HS294T	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.09307196757373126	[232]	[96,50,118,122]	1	hSpCas9	negative selection	6642826
41611185	41611208	17	-	27260156	HS294T	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	1.2921852242556469	[305]	[273,350,184,358]	9	hSpCas9	negative selection	6642827
41611485	41611508	17	-	27260156	HS294T	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.0686947675172291	[11]	[1,1,1,2]	-9	hSpCas9	negative selection	6642828
41611451	41611474	17	-	27260156	HS294T	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.048951997777806455	[691]	[248,242,376,233]	0	hSpCas9	negative selection	6707081
41610929	41610952	17	+	27260156	HS294T	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.4037247521719658	[225]	[63,80,55,61]	-5	hSpCas9	negative selection	6707082
41610844	41610867	17	+	27260156	HS294T	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.22959392662795353	[233]	[74,134,84,135]	3	hSpCas9	negative selection	6707083
41611183	41611206	17	+	27260156	HCC44	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.6376380154228178	[232]	[126,113,214,229]	-7	hSpCas9	negative selection	6764077
41611185	41611208	17	-	27260156	HCC44	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.29055809485305367	[305]	[489,345,392,470]	5	hSpCas9	negative selection	6764078
41611485	41611508	17	-	27260156	HCC44	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.3736157244485359	[11]	[0,0,0,16]	-9	hSpCas9	negative selection	6764079
41611451	41611474	17	-	27260156	HCC44	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.13253475706772433	[691]	[1017,702,1275,546]	2	hSpCas9	negative selection	6828332
41610929	41610952	17	+	27260156	HCC44	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.1985632617953661	[225]	[146,207,264,269]	-3	hSpCas9	negative selection	6828333
41610844	41610867	17	+	27260156	HCC44	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.24147641952437537	[233]	[214,266,362,406]	4	hSpCas9	negative selection	6828334
41611183	41611206	17	+	27260156	G402	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.31223481042767587	[232]	[455,159,332,459]	4	hSpCas9	negative selection	6885328
41611185	41611208	17	-	27260156	G402	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.20256895996152635	[305]	[624,266,270,565]	2	hSpCas9	negative selection	6885329
41611485	41611508	17	-	27260156	G402	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.3004215933004133	[11]	[0,0,19,0]	-9	hSpCas9	negative selection	6885330
41611451	41611474	17	-	27260156	G402	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.023171336424011924	[691]	[570,1507,596,654]	0	hSpCas9	negative selection	6949583
41610929	41610952	17	+	27260156	G402	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.15095607252164234	[225]	[563,325,60,98]	-2	hSpCas9	negative selection	6949584
41610844	41610867	17	+	27260156	G402	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.6097443269474745	[233]	[544,410,543,263]	7	hSpCas9	negative selection	6949585
41611183	41611206	17	+	27260156	L33	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.0315151842790633	[232]	[263,96,151,168]	0	hSpCas9	negative selection	7006579
41611185	41611208	17	-	27260156	L33	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.4533814987650618	[305]	[470,142,306,366]	8	hSpCas9	negative selection	7006580
41611485	41611508	17	-	27260156	L33	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.612362588565663	[11]	[5,0,11,3]	-8	hSpCas9	negative selection	7006581
41611451	41611474	17	-	27260156	L33	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.03832590368876976	[691]	[788,269,393,617]	-1	hSpCas9	negative selection	7070834
41610929	41610952	17	+	27260156	L33	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.6407111482662009	[225]	[155,53,111,113]	-9	hSpCas9	negative selection	7070835
41610844	41610867	17	+	27260156	L33	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.22184400747451738	[233]	[272,101,160,312]	5	hSpCas9	negative selection	7070836
41611183	41611206	17	+	27260156	K562	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.33977031650986445	[232]	[220,165,213,67]	-4	hSpCas9	negative selection	7127830
41611185	41611208	17	-	27260156	K562	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.2541128536928226	[305]	[503,352,201,258]	3	hSpCas9	negative selection	7127831
41611485	41611508	17	-	27260156	K562	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.8278673162685974	[11]	[0,2,0,62]	9	hSpCas9	negative selection	7127832
41611451	41611474	17	-	27260156	K562	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.1883250351769361	[691]	[675,951,731,473]	2	hSpCas9	negative selection	7192085
41610929	41610952	17	+	27260156	K562	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-1.0946806542471264	[225]	[59,13,178,112]	-8	hSpCas9	negative selection	7192086
41610844	41610867	17	+	27260156	K562	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.7896639442731388	[233]	[266,212,672,275]	8	hSpCas9	negative selection	7192087
41611183	41611206	17	+	27260156	HT29	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.2343276473921525	[232]	[292,118,293,247]	-5	hSpCas9	negative selection	7249081
41611185	41611208	17	-	27260156	HT29	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.3693778115117294	[305]	[314,786,464,377]	7	hSpCas9	negative selection	7249082
41611485	41611508	17	-	27260156	HT29	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.5134303579086552	[11]	[11,14,0,12]	-7	hSpCas9	negative selection	7249083
41611451	41611474	17	-	27260156	HT29	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.1399211181258549	[691]	[981,773,627,690]	-3	hSpCas9	negative selection	7313336
41610929	41610952	17	+	27260156	HT29	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.37735325018224763	[225]	[229,182,241,190]	-6	hSpCas9	negative selection	7313337
41610844	41610867	17	+	27260156	HT29	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.558009970178895	[233]	[463,701,277,273]	9	hSpCas9	negative selection	7313338
41611183	41611206	17	+	27260156	MHHES1	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.1468045630372884	[232]	[267,312,354,232]	2	hSpCas9	negative selection	7370332
41611185	41611208	17	-	27260156	MHHES1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.8299347765339559	[305]	[752,484,659,555]	9	hSpCas9	negative selection	7370333
41611485	41611508	17	-	27260156	MHHES1	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	1.4624666334542313	[11]	[33,62,14,37]	9	hSpCas9	negative selection	7370334
41611451	41611474	17	-	27260156	MHHES1	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.15087697752064166	[691]	[935,797,870,842]	2	hSpCas9	negative selection	7434587
41610929	41610952	17	+	27260156	MHHES1	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.4459201563905286	[225]	[99,175,258,194]	-7	hSpCas9	negative selection	7434588
41610844	41610867	17	+	27260156	MHHES1	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.5133280441415511	[233]	[318,698,241,282]	8	hSpCas9	negative selection	7434589
41611183	41611206	17	+	27260156	MEWO	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.20421174150409893	[232]	[255,94,229]	-4	hSpCas9	negative selection	7491583
41611185	41611208	17	-	27260156	MEWO	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.4033354888809259	[305]	[466,360,324]	8	hSpCas9	negative selection	7491584
41611485	41611508	17	-	27260156	MEWO	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.7086309321255193	[11]	[8,10,0]	-8	hSpCas9	negative selection	7491585
41611451	41611474	17	-	27260156	MEWO	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.140604975593007	[691]	[484,775,479]	-3	hSpCas9	negative selection	7555838
41610929	41610952	17	+	27260156	MEWO	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	0.10174375068833452	[225]	[294,186,211]	2	hSpCas9	negative selection	7555839
41610844	41610867	17	+	27260156	MEWO	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.38715728089788504	[233]	[418,197,267]	7	hSpCas9	negative selection	7555840
41611183	41611206	17	+	27260156	LNCAPCLONEFGC	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.48441001530511807	[232]	[146,168,155,130]	-6	hSpCas9	negative selection	7612834
41611185	41611208	17	-	27260156	LNCAPCLONEFGC	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.5842531601684825	[305]	[623,349,318,354]	8	hSpCas9	negative selection	7612835
41611485	41611508	17	-	27260156	LNCAPCLONEFGC	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-2.84002888357783	[11]	[2,0,0,0]	-9	hSpCas9	negative selection	7612836
41611451	41611474	17	-	27260156	LNCAPCLONEFGC	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.1534803431519018	[691]	[587,559,652,465]	-2	hSpCas9	negative selection	7677089
41610929	41610952	17	+	27260156	LNCAPCLONEFGC	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.6866077079412016	[225]	[160,49,78,215]	-8	hSpCas9	negative selection	7677090
41610844	41610867	17	+	27260156	LNCAPCLONEFGC	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.21111926975768014	[233]	[195,152,363,292]	3	hSpCas9	negative selection	7677091
41611183	41611206	17	+	27260156	PANC0327	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.07295311390634662	[232]	[159,149,343,220]	1	hSpCas9	negative selection	7734085
41611185	41611208	17	-	27260156	PANC0327	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.4607035594094583	[305]	[299,405,368,410]	6	hSpCas9	negative selection	7734086
41611485	41611508	17	-	27260156	PANC0327	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.18982121569004917	[11]	[47,0,1,1]	3	hSpCas9	negative selection	7734087
41611451	41611474	17	-	27260156	PANC0327	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.20755876959067632	[691]	[989,739,558,568]	3	hSpCas9	negative selection	7798340
41610929	41610952	17	+	27260156	PANC0327	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.9183593490752266	[225]	[66,39,55,266]	-8	hSpCas9	negative selection	7798341
41610844	41610867	17	+	27260156	PANC0327	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.3508290290107793	[233]	[463,298,116,191]	5	hSpCas9	negative selection	7798342
41611183	41611206	17	+	27260156	NCIH2009	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.42701941990504866	[232]	[453,519,339]	6	hSpCas9	negative selection	7855336
41611185	41611208	17	-	27260156	NCIH2009	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.6386174063580957	[305]	[741,596,672]	8	hSpCas9	negative selection	7855337
41611485	41611508	17	-	27260156	NCIH2009	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	1.237105019928694	[11]	[86,32,7]	9	hSpCas9	negative selection	7855338
41611451	41611474	17	-	27260156	NCIH2009	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.1792810759207844	[691]	[1312,790,547]	-2	hSpCas9	negative selection	7919591
41610929	41610952	17	+	27260156	NCIH2009	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.39825020838646163	[225]	[355,204,180]	-5	hSpCas9	negative selection	7919592
41610844	41610867	17	+	27260156	NCIH2009	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.3772851742491333	[233]	[399,499,366]	5	hSpCas9	negative selection	7919593
41611183	41611206	17	+	27260156	NCIH1373	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.5777077298746334	[232]	[450,312,337,125]	6	hSpCas9	negative selection	7976587
41611185	41611208	17	-	27260156	NCIH1373	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.4439265651389578	[305]	[552,162,482,190]	4	hSpCas9	negative selection	7976588
41611485	41611508	17	-	27260156	NCIH1373	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.283064529502501	[11]	[2,1,12,0]	-8	hSpCas9	negative selection	7976589
41611451	41611474	17	-	27260156	NCIH1373	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.11242428269236127	[691]	[621,856,1049,203]	1	hSpCas9	negative selection	8040842
41610929	41610952	17	+	27260156	NCIH1373	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.5557451185905435	[225]	[480,110,60,22]	-5	hSpCas9	negative selection	8040843
41610844	41610867	17	+	27260156	NCIH1373	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.6027737102671211	[233]	[500,316,324,125]	6	hSpCas9	negative selection	8040844
41611183	41611206	17	+	27260156	PATU8902	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.01499295188160632	[232]	[125,397,422,309]	0	hSpCas9	negative selection	8097838
41611185	41611208	17	-	27260156	PATU8902	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.2860391232683659	[305]	[324,339,785,560]	3	hSpCas9	negative selection	8097839
41611485	41611508	17	-	27260156	PATU8902	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-3.6775645184714474	[11]	[0,0,1,0]	-9	hSpCas9	negative selection	8097840
41611451	41611474	17	-	27260156	PATU8902	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.29307028081107556	[691]	[778,728,718,949]	-3	hSpCas9	negative selection	8162093
41610929	41610952	17	+	27260156	PATU8902	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.506144029537795	[225]	[337,206,190,145]	-5	hSpCas9	negative selection	8162094
41610844	41610867	17	+	27260156	PATU8902	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.5801759097263605	[233]	[404,511,295,822]	6	hSpCas9	negative selection	8162095
41611183	41611206	17	+	27260156	PANC1	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.4304754779061264	[232]	[182,247,121,70]	-6	hSpCas9	negative selection	8219089
41611185	41611208	17	-	27260156	PANC1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.25645871716640684	[305]	[221,507,294,273]	4	hSpCas9	negative selection	8219090
41611485	41611508	17	-	27260156	PANC1	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.8284592995048587	[11]	[0,4,3,11]	-8	hSpCas9	negative selection	8219091
41611451	41611474	17	-	27260156	PANC1	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.26445996872170274	[691]	[595,485,395,488]	-4	hSpCas9	negative selection	8283344
41610929	41610952	17	+	27260156	PANC1	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.26865695637208886	[225]	[66,260,237,107]	-4	hSpCas9	negative selection	8283345
41610844	41610867	17	+	27260156	PANC1	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.4972005321649047	[233]	[339,345,186,269]	7	hSpCas9	negative selection	8283346
41611183	41611206	17	+	27260156	PANC0813	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.3649597022623451	[232]	[508,223,341,348]	6	hSpCas9	negative selection	8340340
41611185	41611208	17	-	27260156	PANC0813	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.66047568207899	[305]	[485,717,327,721]	9	hSpCas9	negative selection	8340341
41611485	41611508	17	-	27260156	PANC0813	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.1216291672063132	[11]	[4,3,13,2]	-8	hSpCas9	negative selection	8340342
41611451	41611474	17	-	27260156	PANC0813	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.04017515042152886	[691]	[936,890,843,517]	0	hSpCas9	negative selection	8404595
41610929	41610952	17	+	27260156	PANC0813	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-1.126661979605449	[225]	[162,137,89,99]	-8	hSpCas9	negative selection	8404596
41610844	41610867	17	+	27260156	PANC0813	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.07622648032018442	[233]	[356,259,279,268]	1	hSpCas9	negative selection	8404597
41611183	41611206	17	+	27260156	RDES	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.0500296507353748	[232]	[221,219,366,319]	0	hSpCas9	negative selection	8461591
41611185	41611208	17	-	27260156	RDES	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.4621551566901022	[305]	[449,500,471,508]	7	hSpCas9	negative selection	8461592
41611485	41611508	17	-	27260156	RDES	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.30822332172620026	[11]	[4,2,28,9]	-5	hSpCas9	negative selection	8461593
41611451	41611474	17	-	27260156	RDES	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.09532820736351194	[691]	[550,682,850,957]	-1	hSpCas9	negative selection	8525846
41610929	41610952	17	+	27260156	RDES	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.6201129973423238	[225]	[80,136,336,141]	-8	hSpCas9	negative selection	8525847
41610844	41610867	17	+	27260156	RDES	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.2382810791158455	[233]	[297,298,347,321]	4	hSpCas9	negative selection	8525848
41611183	41611206	17	+	27260156	PC3	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.06892254556424704	[232]	[170,206,377,185]	-1	hSpCas9	negative selection	8582842
41611185	41611208	17	-	27260156	PC3	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.571844309710686	[305]	[308,424,623,542]	9	hSpCas9	negative selection	8582843
41611485	41611508	17	-	27260156	PC3	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.6584119093485032	[11]	[1,5,7,0]	-9	hSpCas9	negative selection	8582844
41611451	41611474	17	-	27260156	PC3	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.0714666856280568	[691]	[422,718,1286,756]	1	hSpCas9	negative selection	8647097
41610929	41610952	17	+	27260156	PC3	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.05707098838129232	[225]	[81,197,445,278]	-1	hSpCas9	negative selection	8647098
41610844	41610867	17	+	27260156	PC3	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.2433410465459036	[233]	[105,296,572,300]	5	hSpCas9	negative selection	8647099
41611183	41611206	17	+	27260156	PATU8988T	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.37798193087029186	[232]	[241,188,106,155]	-6	hSpCas9	negative selection	8704093
41611185	41611208	17	-	27260156	PATU8988T	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.7277675394431026	[305]	[531,397,563,451]	9	hSpCas9	negative selection	8704094
41611485	41611508	17	-	27260156	PATU8988T	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-1.0612972439107953	[11]	[2,5,9,2]	-9	hSpCas9	negative selection	8704095
41611451	41611474	17	-	27260156	PATU8988T	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.06470578101853885	[691]	[778,643,596,779]	1	hSpCas9	negative selection	8768348
41610929	41610952	17	+	27260156	PATU8988T	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-1.0188184209070206	[225]	[99,130,98,102]	-9	hSpCas9	negative selection	8768349
41610844	41610867	17	+	27260156	PATU8988T	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.3951316747905488	[233]	[399,293,124,378]	6	hSpCas9	negative selection	8768350
41611183	41611206	17	+	27260156	T47D	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.05796940726131239	[232]	[326,198,191,333]	-1	hSpCas9	negative selection	8825344
41611185	41611208	17	-	27260156	T47D	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.38600523393615715	[305]	[495,401,469,501]	7	hSpCas9	negative selection	8825345
41611485	41611508	17	-	27260156	T47D	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.3810051569174622	[11]	[24,9,2,4]	-7	hSpCas9	negative selection	8825346
41611451	41611474	17	-	27260156	T47D	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	-0.10921524102119601	[691]	[823,645,799,726]	-2	hSpCas9	negative selection	8889599
41610929	41610952	17	+	27260156	T47D	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-1.1182842741604289	[225]	[104,184,94,93]	-9	hSpCas9	negative selection	8889600
41610844	41610867	17	+	27260156	T47D	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.5081698279171074	[233]	[318,332,456,446]	9	hSpCas9	negative selection	8889601
41611183	41611206	17	+	27260156	SU8686	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.14559659287119375	[232]	[224,223,329,249]	2	hSpCas9	negative selection	8946595
41611185	41611208	17	-	27260156	SU8686	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.7857772573794437	[305]	[608,395,562,528]	9	hSpCas9	negative selection	8946596
41611485	41611508	17	-	27260156	SU8686	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.6637823936900311	[11]	[6,10,6,3]	-7	hSpCas9	negative selection	8946597
41611451	41611474	17	-	27260156	SU8686	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.18688919346948385	[691]	[595,691,1011,871]	3	hSpCas9	negative selection	9010850
41610929	41610952	17	+	27260156	SU8686	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.7014120280020639	[225]	[108,168,109,164]	-8	hSpCas9	negative selection	9010851
41610844	41610867	17	+	27260156	SU8686	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.598403716119956	[233]	[317,365,342,381]	8	hSpCas9	negative selection	9010852
41611183	41611206	17	+	27260156	SKES1	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.30803065153481035	[232]	[216,134,191,200]	-6	hSpCas9	negative selection	9067846
41611185	41611208	17	-	27260156	SKES1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.5338319295765723	[305]	[392,738,356,318]	9	hSpCas9	negative selection	9067847
41611485	41611508	17	-	27260156	SKES1	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.2962404804373122	[11]	[2,34,0,19]	6	hSpCas9	negative selection	9067848
41611451	41611474	17	-	27260156	SKES1	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.22402639790758916	[691]	[1007,862,656,733]	5	hSpCas9	negative selection	9132101
41610929	41610952	17	+	27260156	SKES1	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.43588442611099354	[225]	[147,125,187,191]	-7	hSpCas9	negative selection	9132102
41610844	41610867	17	+	27260156	SKES1	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.3696410184596296	[233]	[407,377,294,162]	7	hSpCas9	negative selection	9132103
41611183	41611206	17	+	27260156	TOV112D	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.13725080431692716	[232]	[251,377,108,314]	2	hSpCas9	negative selection	9189097
41611185	41611208	17	-	27260156	TOV112D	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.48487480403521876	[305]	[411,530,308,484]	8	hSpCas9	negative selection	9189098
41611485	41611508	17	-	27260156	TOV112D	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-3.2325673118467595	[11]	[0,0,0,1]	-9	hSpCas9	negative selection	9189099
41611451	41611474	17	-	27260156	TOV112D	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.06853011479722848	[691]	[678,816,587,836]	1	hSpCas9	negative selection	9253352
41610929	41610952	17	+	27260156	TOV112D	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.11957555708876799	[225]	[237,250,219,138]	-2	hSpCas9	negative selection	9253353
41610844	41610867	17	+	27260156	TOV112D	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.684989744123756	[233]	[309,416,414,368]	9	hSpCas9	negative selection	9253354
41611183	41611206	17	+	27260156	TC71	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	-0.1031122641952873	[232]	[284,259,188,193]	-3	hSpCas9	negative selection	9310348
41611185	41611208	17	-	27260156	TC71	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.21448440446311973	[305]	[302,420,336,469]	5	hSpCas9	negative selection	9310349
41611485	41611508	17	-	27260156	TC71	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	-0.4670705064047169	[11]	[8,5,3,18]	-8	hSpCas9	negative selection	9310350
41611451	41611474	17	-	27260156	TC71	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.08289795134655042	[691]	[749,842,675,883]	2	hSpCas9	negative selection	9374603
41610929	41610952	17	+	27260156	TC71	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	0.06607004309392261	[225]	[267,352,209,179]	1	hSpCas9	negative selection	9374604
41610844	41610867	17	+	27260156	TC71	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.43371880218803494	[233]	[322,296,371,363]	8	hSpCas9	negative selection	9374605
41611183	41611206	17	+	27260156	TC32	viability	CTCCACGTTCACATCTCCGCCGG	KRT16	ENSG00000186832	0.15165125753805042	[232]	[224,233,259,246]	2	hSpCas9	negative selection	9431599
41611185	41611208	17	-	27260156	TC32	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.34321916741311015	[305]	[297,294,450,447]	6	hSpCas9	negative selection	9431600
41611485	41611508	17	-	27260156	TC32	viability	TGCCAGGTATGAGCATGAACTGG	KRT16	ENSG00000186832	0.4534980777721467	[11]	[13,24,4,10]	7	hSpCas9	negative selection	9431601
41611451	41611474	17	-	27260156	TC32	viability	ACTGTGGAGGCCGACGTCAATGG	KRT16	ENSG00000186832	0.11569088006802375	[691]	[775,477,993,651]	2	hSpCas9	negative selection	9495854
41610929	41610952	17	+	27260156	TC32	viability	GCTCTGTACCAGTTCGCTGTTGG	KRT16	ENSG00000186832	-0.7762796920690271	[225]	[183,50,89,180]	-9	hSpCas9	negative selection	9495855
41610844	41610867	17	+	27260156	TC32	viability	TCCTTCATACCATGCTGAGCTGG	KRT16	ENSG00000186832	0.5144565143196034	[233]	[217,314,347,376]	8	hSpCas9	negative selection	9495856
41610189	41610212	17	-	27869803	HPAFII	viability after 27 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.8364824356679235	[284]	[102,67,NaN]	-5	hSpCas9	negative selection	9560740
41611081	41611104	17	-	27869803	HPAFII	viability after 27 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.10631071467431075	[555]	[282,261,NaN]	-1	hSpCas9	negative selection	9560741
41610189	41610212	17	-	27869803	HPAFII	viability after 15 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.04856532700494476	[284]	[502,200,NaN]	0	hSpCas9	negative selection	9643189
41611081	41611104	17	-	27869803	HPAFII	viability after 15 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.358018311784693	[555]	[427,489,NaN]	-4	hSpCas9	negative selection	9643190
41610189	41610212	17	-	27869803	ASPC1	viability after 36 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.5985916279808507	[1129]	[174,205,360]	-5	hSpCas9	negative selection	9725638
41611081	41611104	17	-	27869803	ASPC1	viability after 36 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.5759362834113416	[1366]	[181,393,354]	-5	hSpCas9	negative selection	9725639
41610189	41610212	17	-	27869803	PATU8988S	viability after 35 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.12207486406056323	[810]	[342,367,NaN]	1	hSpCas9	negative selection	9808087
41611081	41611104	17	-	27869803	PATU8988S	viability after 35 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.15961264001715414	[1170]	[301,542,NaN]	-2	hSpCas9	negative selection	9808088
41610189	41610212	17	-	27869803	PATU8988S	viability after 31 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.0997047886784333	[810]	[237,382,NaN]	-1	hSpCas9	negative selection	9890536
41611081	41611104	17	-	27869803	PATU8988S	viability after 31 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	0.23302604415139294	[1170]	[451,671,NaN]	3	hSpCas9	negative selection	9890537
41610189	41610212	17	-	27869803	HPAFII	viability after 35 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.5448713011765403	[284]	[128,64,NaN]	-3	hSpCas9	negative selection	9972985
41611081	41611104	17	-	27869803	HPAFII	viability after 35 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	0.17757175741197417	[555]	[172,481,NaN]	1	hSpCas9	negative selection	9972986
41610189	41610212	17	-	27869803	HPAFII	viability after 31 days	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.3458855031032292	[284]	[88,165,NaN]	-2	hSpCas9	negative selection	10055434
41611081	41611104	17	-	27869803	HPAFII	viability after 31 days	ACCGCAGAGACGCTGAGACCTGG	KRT16	ENSG00000186832	-0.14207732670712914	[555]	[232,336,NaN]	-1	hSpCas9	negative selection	10055435
41611332	41611355	17	+	28162770	P31FUJ	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.7500953678949076	[296]	[586]	8	hSpCas9	negative selection	10181296
41610189	41610212	17	-	28162770	P31FUJ	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.18280586835060064	[631]	[842]	2	hSpCas9	negative selection	10181297
41610955	41610978	17	-	28162770	P31FUJ	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	1.153415018827964	[157]	[412]	9	hSpCas9	negative selection	10181298
41610899	41610922	17	-	28162770	P31FUJ	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-1.2532663069740941	[212]	[104]	-7	hSpCas9	negative selection	10181299
41611185	41611208	17	-	28162770	P31FUJ	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.12588700049786672	[90]	[97]	-1	hSpCas9	negative selection	10181300
41610888	41610911	17	-	28162770	P31FUJ	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	-0.5065630168412307	[161]	[133]	-4	hSpCas9	negative selection	10181301
41611113	41611136	17	-	28162770	P31FUJ	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-0.10839186222443492	[321]	[350]	-1	hSpCas9	negative selection	10181302
41612621	41612644	17	-	28162770	P31FUJ	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	0.4223355903663329	[213]	[336]	5	hSpCas9	negative selection	10181303
41611441	41611464	17	+	28162770	P31FUJ	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.044205143972019356	[273]	[331]	0	hSpCas9	negative selection	10181304
41611080	41611103	17	+	28162770	P31FUJ	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.7766996633527761	[226]	[456]	8	hSpCas9	negative selection	10181305
41611332	41611355	17	+	28162770	TF1	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	NaN	[NaN]	[491]	1	hSpCas9	negative selection	10350662
41610189	41610212	17	-	28162770	TF1	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	NaN	[NaN]	[540]	1	hSpCas9	negative selection	10350663
41610955	41610978	17	-	28162770	TF1	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	NaN	[NaN]	[193]	1	hSpCas9	negative selection	10350664
41610899	41610922	17	-	28162770	TF1	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10350665
41611185	41611208	17	-	28162770	TF1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	NaN	[NaN]	[32]	1	hSpCas9	negative selection	10350666
41610888	41610911	17	-	28162770	TF1	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	NaN	[NaN]	[184]	1	hSpCas9	negative selection	10350667
41611113	41611136	17	-	28162770	TF1	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	NaN	[NaN]	[417]	1	hSpCas9	negative selection	10350668
41612621	41612644	17	-	28162770	TF1	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10350669
41611441	41611464	17	+	28162770	TF1	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	NaN	[NaN]	[227]	1	hSpCas9	negative selection	10350670
41611080	41611103	17	+	28162770	TF1	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	NaN	[NaN]	[379]	1	hSpCas9	negative selection	10350671
41611332	41611355	17	+	28162770	SKM1	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.8794748114255758	[106]	[347]	8	hSpCas9	negative selection	10520028
41610189	41610212	17	-	28162770	SKM1	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.5335705151227302	[121]	[148]	-4	hSpCas9	negative selection	10520029
41610955	41610978	17	-	28162770	SKM1	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.251247284008633	[47]	[100]	2	hSpCas9	negative selection	10520030
41610899	41610922	17	-	28162770	SKM1	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-0.17733295117658168	[70]	[110]	-1	hSpCas9	negative selection	10520031
41611185	41611208	17	-	28162770	SKM1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.9094645392723446	[33]	[31]	-6	hSpCas9	negative selection	10520032
41610888	41610911	17	-	28162770	SKM1	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	-0.0514835441447728	[50]	[86]	0	hSpCas9	negative selection	10520033
41611113	41611136	17	-	28162770	SKM1	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-0.8053229568753753	[85]	[86]	-6	hSpCas9	negative selection	10520034
41612621	41612644	17	-	28162770	SKM1	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.3235481905555242	[62]	[88]	-3	hSpCas9	negative selection	10520035
41611441	41611464	17	+	28162770	SKM1	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	1.0625210845580586	[51]	[191]	8	hSpCas9	negative selection	10520036
41611080	41611103	17	+	28162770	SKM1	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.34792330342030686	[47]	[107]	3	hSpCas9	negative selection	10520037
41611332	41611355	17	+	28162770	SKM1	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.8794748114255758	[106]	[347]	8	hSpCas9	negative selection	10689394
41610189	41610212	17	-	28162770	SKM1	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.5335705151227302	[121]	[148]	-4	hSpCas9	negative selection	10689395
41610955	41610978	17	-	28162770	SKM1	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.251247284008633	[47]	[100]	2	hSpCas9	negative selection	10689396
41610899	41610922	17	-	28162770	SKM1	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-0.17733295117658168	[70]	[110]	-1	hSpCas9	negative selection	10689397
41611185	41611208	17	-	28162770	SKM1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.9094645392723446	[33]	[31]	-6	hSpCas9	negative selection	10689398
41610888	41610911	17	-	28162770	SKM1	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	-0.0514835441447728	[50]	[86]	0	hSpCas9	negative selection	10689399
41611113	41611136	17	-	28162770	SKM1	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-0.8053229568753753	[85]	[86]	-6	hSpCas9	negative selection	10689400
41612621	41612644	17	-	28162770	SKM1	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.3235481905555242	[62]	[88]	-3	hSpCas9	negative selection	10689401
41611441	41611464	17	+	28162770	SKM1	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	1.0625210845580586	[51]	[191]	8	hSpCas9	negative selection	10689402
41611080	41611103	17	+	28162770	SKM1	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.34792330342030686	[47]	[107]	3	hSpCas9	negative selection	10689403
41611332	41611355	17	+	28162770	PL21	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	-0.0999841100796941	[393]	[159]	0	hSpCas9	negative selection	10858760
41610189	41610212	17	-	28162770	PL21	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.771173276579074	[450]	[334]	6	hSpCas9	negative selection	10858761
41610955	41610978	17	-	28162770	PL21	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	1.529845059968402	[147]	[185]	9	hSpCas9	negative selection	10858762
41610899	41610922	17	-	28162770	PL21	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-1.0093137511396297	[184]	[39]	-6	hSpCas9	negative selection	10858763
41611185	41611208	17	-	28162770	PL21	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.6077975834025664	[97]	[64]	5	hSpCas9	negative selection	10858764
41610888	41610911	17	-	28162770	PL21	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	1.0263725467526137	[140]	[124]	8	hSpCas9	negative selection	10858765
41611113	41611136	17	-	28162770	PL21	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	0.1297502865979221	[188]	[89]	1	hSpCas9	negative selection	10858766
41612621	41612644	17	-	28162770	PL21	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.12178848039804213	[189]	[75]	-1	hSpCas9	negative selection	10858767
41611441	41611464	17	+	28162770	PL21	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.8099573038967519	[210]	[160]	7	hSpCas9	negative selection	10858768
41611080	41611103	17	+	28162770	PL21	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.7384088797624349	[156]	[113]	6	hSpCas9	negative selection	10858769
41611332	41611355	17	+	28162770	P31FUJ	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.7500953678949076	[296]	[586]	8	hSpCas9	negative selection	11028126
41610189	41610212	17	-	28162770	P31FUJ	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.18280586835060064	[631]	[842]	2	hSpCas9	negative selection	11028127
41610955	41610978	17	-	28162770	P31FUJ	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	1.153415018827964	[157]	[412]	9	hSpCas9	negative selection	11028128
41610899	41610922	17	-	28162770	P31FUJ	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-1.2532663069740941	[212]	[104]	-7	hSpCas9	negative selection	11028129
41611185	41611208	17	-	28162770	P31FUJ	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.12588700049786672	[90]	[97]	-1	hSpCas9	negative selection	11028130
41610888	41610911	17	-	28162770	P31FUJ	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	-0.5065630168412307	[161]	[133]	-4	hSpCas9	negative selection	11028131
41611113	41611136	17	-	28162770	P31FUJ	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-0.10839186222443492	[321]	[350]	-1	hSpCas9	negative selection	11028132
41612621	41612644	17	-	28162770	P31FUJ	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	0.4223355903663329	[213]	[336]	5	hSpCas9	negative selection	11028133
41611441	41611464	17	+	28162770	P31FUJ	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.044205143972019356	[273]	[331]	0	hSpCas9	negative selection	11028134
41611080	41611103	17	+	28162770	P31FUJ	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.7766996633527761	[226]	[456]	8	hSpCas9	negative selection	11028135
41611332	41611355	17	+	28162770	OCIAML5	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.6851427984087911	[214]	[623]	6	hSpCas9	negative selection	11197492
41610189	41610212	17	-	28162770	OCIAML5	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	0.014774872305511222	[430]	[785]	0	hSpCas9	negative selection	11197493
41610955	41610978	17	-	28162770	OCIAML5	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.2739869321423997	[114]	[250]	2	hSpCas9	negative selection	11197494
41610899	41610922	17	-	28162770	OCIAML5	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	0.5264450523897329	[94]	[246]	4	hSpCas9	negative selection	11197495
41611185	41611208	17	-	28162770	OCIAML5	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.8944850721314073	[44]	[150]	7	hSpCas9	negative selection	11197496
41610888	41610911	17	-	28162770	OCIAML5	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.8819517392518725	[97]	[325]	7	hSpCas9	negative selection	11197497
41611113	41611136	17	-	28162770	OCIAML5	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	0.04586151987613296	[182]	[340]	0	hSpCas9	negative selection	11197498
41612621	41612644	17	-	28162770	OCIAML5	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.4796487055229416	[145]	[188]	-3	hSpCas9	negative selection	11197499
41611441	41611464	17	+	28162770	OCIAML5	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	1.3895194157057618	[95]	[453]	9	hSpCas9	negative selection	11197500
41611080	41611103	17	+	28162770	OCIAML5	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	1.2074753747904086	[88]	[370]	8	hSpCas9	negative selection	11197501
41611332	41611355	17	+	28162770	EOL1	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.9265529074609116	[718]	[719]	7	hSpCas9	negative selection	11366858
41610189	41610212	17	-	28162770	EOL1	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.012763480951723416	[652]	[340]	0	hSpCas9	negative selection	11366859
41610955	41610978	17	-	28162770	EOL1	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.5026238867064508	[279]	[208]	4	hSpCas9	negative selection	11366860
41610899	41610922	17	-	28162770	EOL1	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	0.37800548916319887	[351]	[240]	3	hSpCas9	negative selection	11366861
41611185	41611208	17	-	28162770	EOL1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.16923286752543648	[210]	[124]	1	hSpCas9	negative selection	11366862
41610888	41610911	17	-	28162770	EOL1	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.4720355668730279	[285]	[208]	4	hSpCas9	negative selection	11366863
41611113	41611136	17	-	28162770	EOL1	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	1.5361659042927438	[285]	[436]	9	hSpCas9	negative selection	11366864
41612621	41612644	17	-	28162770	EOL1	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	0.4025950683751787	[223]	[155]	3	hSpCas9	negative selection	11366865
41611441	41611464	17	+	28162770	EOL1	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	-0.9897223544035814	[244]	[64]	-6	hSpCas9	negative selection	11366866
41611080	41611103	17	+	28162770	EOL1	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.025633896684848972	[247]	[132]	0	hSpCas9	negative selection	11366867
41611332	41611355	17	+	28162770	MOLM13	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	1.825503444235191	[566]	[1452]	9	hSpCas9	negative selection	11536224
41610189	41610212	17	-	28162770	MOLM13	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.20316209589028644	[983]	[617]	-1	hSpCas9	negative selection	11536225
41610955	41610978	17	-	28162770	MOLM13	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	-0.2255577494549748	[282]	[174]	-1	hSpCas9	negative selection	11536226
41610899	41610922	17	-	28162770	MOLM13	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-0.2642591963238514	[298]	[179]	-2	hSpCas9	negative selection	11536227
41611185	41611208	17	-	28162770	MOLM13	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	1.549129229504756	[163]	[346]	9	hSpCas9	negative selection	11536228
41610888	41610911	17	-	28162770	MOLM13	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.5770528250323126	[228]	[246]	4	hSpCas9	negative selection	11536229
41611113	41611136	17	-	28162770	MOLM13	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-1.0726789998181239	[319]	[109]	-5	hSpCas9	negative selection	11536230
41612621	41612644	17	-	28162770	MOLM13	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-1.3029396644879112	[272]	[79]	-6	hSpCas9	negative selection	11536231
41611441	41611464	17	+	28162770	MOLM13	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	-0.04775205867267063	[192]	[134]	0	hSpCas9	negative selection	11536232
41611080	41611103	17	+	28162770	MOLM13	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	1.9990454385699412	[172]	[499]	9	hSpCas9	negative selection	11536233
41611332	41611355	17	+	28162770	HEL	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.23928930699672524	[495]	[374]	2	hSpCas9	negative selection	11705590
41610189	41610212	17	-	28162770	HEL	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.1760785161541365	[694]	[393]	-1	hSpCas9	negative selection	11705591
41610955	41610978	17	-	28162770	HEL	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.9524233311329722	[212]	[263]	8	hSpCas9	negative selection	11705592
41610899	41610922	17	-	28162770	HEL	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	0.5606377517854634	[234]	[221]	5	hSpCas9	negative selection	11705593
41611185	41611208	17	-	28162770	HEL	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.5932701557360571	[88]	[85]	5	hSpCas9	negative selection	11705594
41610888	41610911	17	-	28162770	HEL	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	1.082688901244688	[243]	[330]	8	hSpCas9	negative selection	11705595
41611113	41611136	17	-	28162770	HEL	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	0.5849181776120148	[279]	[268]	5	hSpCas9	negative selection	11705596
41612621	41612644	17	-	28162770	HEL	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	0.3641381687770953	[204]	[168]	3	hSpCas9	negative selection	11705597
41611441	41611464	17	+	28162770	HEL	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.5238614361484369	[176]	[162]	4	hSpCas9	negative selection	11705598
41611080	41611103	17	+	28162770	HEL	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	1.4450084648981782	[202]	[353]	9	hSpCas9	negative selection	11705599
41611332	41611355	17	+	28162770	MV411	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.14574215371342447	[381]	[355]	1	hSpCas9	negative selection	11874956
41610189	41610212	17	-	28162770	MV411	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.5164322270850914	[432]	[254]	-4	hSpCas9	negative selection	11874957
41610955	41610978	17	-	28162770	MV411	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	-0.08475887955841416	[140]	[111]	0	hSpCas9	negative selection	11874958
41610899	41610922	17	-	28162770	MV411	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	0.5410007544167761	[225]	[276]	5	hSpCas9	negative selection	11874959
41611185	41611208	17	-	28162770	MV411	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.8166927866369402	[91]	[43]	-5	hSpCas9	negative selection	11874960
41610888	41610911	17	-	28162770	MV411	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	0.5154987736914018	[190]	[229]	4	hSpCas9	negative selection	11874961
41611113	41611136	17	-	28162770	MV411	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-0.34375690364989553	[231]	[153]	-3	hSpCas9	negative selection	11874962
41612621	41612644	17	-	28162770	MV411	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	0.5346002275094611	[167]	[204]	5	hSpCas9	negative selection	11874963
41611441	41611464	17	+	28162770	MV411	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.739833932767859	[117]	[165]	6	hSpCas9	negative selection	11874964
41611080	41611103	17	+	28162770	MV411	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.6122018435803955	[145]	[187]	5	hSpCas9	negative selection	11874965
41611332	41611355	17	+	28162770	MONOMAC1	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	-0.27669629623720426	[241]	[228]	-2	hSpCas9	negative selection	12044322
41610189	41610212	17	-	28162770	MONOMAC1	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.15521667136492678	[305]	[314]	-1	hSpCas9	negative selection	12044323
41610955	41610978	17	-	28162770	MONOMAC1	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.29938897905994527	[111]	[157]	3	hSpCas9	negative selection	12044324
41610899	41610922	17	-	28162770	MONOMAC1	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-0.3135508557859789	[115]	[106]	-3	hSpCas9	negative selection	12044325
41611185	41611208	17	-	28162770	MONOMAC1	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.6697898441946849	[67]	[48]	-5	hSpCas9	negative selection	12044326
41610888	41610911	17	-	28162770	MONOMAC1	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	-0.5913157861716003	[137]	[104]	-5	hSpCas9	negative selection	12044327
41611113	41611136	17	-	28162770	MONOMAC1	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	-1.0874123558850557	[151]	[81]	-7	hSpCas9	negative selection	12044328
41612621	41612644	17	-	28162770	MONOMAC1	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.4649700523061867	[117]	[97]	-4	hSpCas9	negative selection	12044329
41611441	41611464	17	+	28162770	MONOMAC1	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.48648948814519194	[98]	[158]	5	hSpCas9	negative selection	12044330
41611080	41611103	17	+	28162770	MONOMAC1	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	-0.26060197583701983	[115]	[110]	-2	hSpCas9	negative selection	12044331
41611332	41611355	17	+	28162770	OCIAML2	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	-0.07208044875188624	[65]	[347]	0	hSpCas9	negative selection	12213688
41610189	41610212	17	-	28162770	OCIAML2	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.04800773073532616	[82]	[444]	0	hSpCas9	negative selection	12213689
41610955	41610978	17	-	28162770	OCIAML2	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.4341218596100224	[44]	[336]	4	hSpCas9	negative selection	12213690
41610899	41610922	17	-	28162770	OCIAML2	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-0.5961607073260201	[29]	[109]	-4	hSpCas9	negative selection	12213691
41611185	41611208	17	-	28162770	OCIAML2	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	-0.38721381705452373	[20]	[88]	-3	hSpCas9	negative selection	12213692
41610888	41610911	17	-	28162770	OCIAML2	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	-0.031208167336358117	[32]	[178]	0	hSpCas9	negative selection	12213693
41611113	41611136	17	-	28162770	OCIAML2	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	1.0625501333764487	[25]	[300]	8	hSpCas9	negative selection	12213694
41612621	41612644	17	-	28162770	OCIAML2	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	0.32036165060655586	[37]	[262]	3	hSpCas9	negative selection	12213695
41611441	41611464	17	+	28162770	OCIAML2	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.7793484277661863	[36]	[351]	7	hSpCas9	negative selection	12213696
41611080	41611103	17	+	28162770	OCIAML2	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	-0.2722162668401531	[38]	[178]	-2	hSpCas9	negative selection	12213697
41611332	41611355	17	+	28162770	OCIAML3	viability	GCAGCGACCGTACCTCCTCGTGG	KRT16	ENSG00000186832	0.951271158924511	[85]	[501]	8	hSpCas9	negative selection	12383054
41610189	41610212	17	-	28162770	OCIAML3	viability	CAATCCTATTCTTCCCGCGAGGG	KRT16	ENSG00000186832	-0.37653070940183175	[125]	[292]	-3	hSpCas9	negative selection	12383055
41610955	41610978	17	-	28162770	OCIAML3	viability	CGAGGAGCTGAACAAAGAAGTGG	KRT16	ENSG00000186832	0.16342205640175844	[41]	[141]	1	hSpCas9	negative selection	12383056
41610899	41610922	17	-	28162770	OCIAML3	viability	GTGAGGTGACGGAGCTCCGGAGG	KRT16	ENSG00000186832	-0.25469746720856434	[65]	[166]	-2	hSpCas9	negative selection	12383057
41611185	41611208	17	-	28162770	OCIAML3	viability	GACCGGCGGAGATGTGAACGTGG	KRT16	ENSG00000186832	0.6506147283957502	[22]	[108]	6	hSpCas9	negative selection	12383058
41610888	41610911	17	-	28162770	OCIAML3	viability	GAGCTCCGGAGGGTGCTCCAGGG	KRT16	ENSG00000186832	1.0093333897118477	[25]	[157]	8	hSpCas9	negative selection	12383059
41611113	41611136	17	-	28162770	OCIAML3	viability	GCGTGACCAGTACGAGCAGATGG	KRT16	ENSG00000186832	0.5149267312290008	[50]	[219]	5	hSpCas9	negative selection	12383060
41612621	41612644	17	-	28162770	OCIAML3	viability	GGCTCCTGCGGCATCGGAGGCGG	KRT16	ENSG00000186832	-0.009045139603006846	[65]	[197]	0	hSpCas9	negative selection	12383061
41611441	41611464	17	+	28162770	OCIAML3	viability	CCGGCGCAGGCCATTGACGTCGG	KRT16	ENSG00000186832	0.6713369261968317	[51]	[249]	6	hSpCas9	negative selection	12383062
41611080	41611103	17	+	28162770	OCIAML3	viability	ACCAGGTCTCAGCGTCTCTGCGG	KRT16	ENSG00000186832	0.4556231274004373	[49]	[206]	4	hSpCas9	negative selection	12383063