Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3875
• Symbol:KRT18
• Description:keratin 18

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT18

Export (tab separated) Export to Excel

Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52949359	52949382	12	+	26472758	Jiyoye	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	2.3791610053362766	[38]	[152]	9	hSpCas9	negative selection	86252
52950324	52950347	12	+	26472758	Jiyoye	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	0.24797678665661937	[66]	[59]	2	hSpCas9	negative selection	86253
52950744	52950767	12	+	26472758	Jiyoye	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.22034758144332833	[257]	[166]	-1	hSpCas9	negative selection	86254
52949321	52949344	12	+	26472758	Jiyoye	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.27089652360676425	[167]	[104]	-2	hSpCas9	negative selection	86255
52951843	52951866	12	-	26472758	Jiyoye	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.3240078600663267	[165]	[99]	-2	hSpCas9	negative selection	86256
52952109	52952132	12	+	26472758	Jiyoye	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	2.159737830723098	[91]	[309]	9	hSpCas9	negative selection	86257
52950825	52950848	12	+	26472758	Jiyoye	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.43102212346024105	[59]	[60]	3	hSpCas9	negative selection	86258
52952716	52952739	12	+	26472758	Jiyoye	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.6350900872533642	[297]	[348]	4	hSpCas9	negative selection	86259
52952196	52952219	12	+	26472758	Jiyoye	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	86260
52949359	52949382	12	+	26472758	KBM7	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.3618723137632717	[388,305]	[256,164]	4	hSpCas9	negative selection	277370
52950324	52950347	12	+	26472758	KBM7	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-0.12667133436156042	[382,381]	[221,114]	-1	hSpCas9	negative selection	277371
52950744	52950767	12	+	26472758	KBM7	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.19371318502083285	[693,599]	[487,220]	2	hSpCas9	negative selection	277372
52949321	52949344	12	+	26472758	KBM7	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.00928315346234583	[505,521]	[294,193]	0	hSpCas9	negative selection	277373
52951843	52951866	12	-	26472758	KBM7	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.2243306668275451	[433,453]	[236,128]	-2	hSpCas9	negative selection	277374
52952109	52952132	12	+	26472758	KBM7	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.7185471545056901	[693,578]	[408,562]	7	hSpCas9	negative selection	277375
52950825	52950848	12	+	26472758	KBM7	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.5963397625664826	[290,226]	[216,151]	6	hSpCas9	negative selection	277376
52952716	52952739	12	+	26472758	KBM7	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.5655826237311563	[1618,1580]	[1410,854]	6	hSpCas9	negative selection	277377
52952196	52952219	12	+	26472758	KBM7	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-1.9159999289955985	[179,147]	[32,8]	-8	hSpCas9	negative selection	277378
52949359	52949382	12	+	26472758	Raji	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.9667231284364818	[182]	[82]	8	hSpCas9	negative selection	468488
52950324	52950347	12	+	26472758	Raji	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-0.13293079396011082	[188]	[39]	-1	hSpCas9	negative selection	468489
52950744	52950767	12	+	26472758	Raji	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.7854554404862372	[214]	[85]	7	hSpCas9	negative selection	468490
52949321	52949344	12	+	26472758	Raji	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.49112549718550436	[320]	[52]	-4	hSpCas9	negative selection	468491
52951843	52951866	12	-	26472758	Raji	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	1.095606367597246	[245]	[121]	8	hSpCas9	negative selection	468492
52952109	52952132	12	+	26472758	Raji	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.09424813318446557	[330]	[81]	0	hSpCas9	negative selection	468493
52950825	52950848	12	+	26472758	Raji	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	1.1639670637399668	[99]	[51]	8	hSpCas9	negative selection	468494
52952716	52952739	12	+	26472758	Raji	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.18698501045525928	[616]	[162]	1	hSpCas9	negative selection	468495
52952196	52952219	12	+	26472758	Raji	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-4.335559960475129	[86]	[0]	-9	hSpCas9	negative selection	468496
52949359	52949382	12	+	26472758	K562	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.9269365378102766	[242]	[389]	7	hSpCas9	negative selection	659606
52950324	52950347	12	+	26472758	K562	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.8584995852791197	[304]	[70]	-7	hSpCas9	negative selection	659607
52950744	52950767	12	+	26472758	K562	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.3974980576708362	[401]	[446]	3	hSpCas9	negative selection	659608
52949321	52949344	12	+	26472758	K562	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-1.05056630238267	[556]	[226]	-5	hSpCas9	negative selection	659609
52951843	52951866	12	-	26472758	K562	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.37153064556978604	[379]	[414]	3	hSpCas9	negative selection	659610
52952109	52952132	12	+	26472758	K562	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.9070238314333141	[421]	[667]	7	hSpCas9	negative selection	659611
52950825	52950848	12	+	26472758	K562	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.3727428246419864	[128]	[140]	3	hSpCas9	negative selection	659612
52952716	52952739	12	+	26472758	K562	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.31829897923477213	[1198]	[1261]	2	hSpCas9	negative selection	659613
52952196	52952219	12	+	26472758	K562	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-0.937188078823501	[92]	[40]	-5	hSpCas9	negative selection	659614
52950744	52950767	12	+	26627737	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.9226499929137908	[331]	[156,179,244]	8	hSpCas9	negative selection	784312
52950744	52950767	12	+	26627737	GBM cells	viability after 5 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.12339628683940318	[390]	[192,191]	-2	hSpCas9	negative selection	866627
52950744	52950767	12	+	26627737	GBM cells	viability after 13 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0018980684727334385	[390]	[239,189]	0	hSpCas9	negative selection	948942
52950744	52950767	12	+	26627737	GBM cells	viability after 21 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.13153590282629224	[390]	[227,236]	1	hSpCas9	negative selection	1031257
52950744	52950767	12	+	26627737	RPE1	viability after 9 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.8953247176497124	[623]	[327,408]	6	hSpCas9	negative selection	1113572
52950744	52950767	12	+	26627737	RPE1	viability after 12 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.33707334189318894	[623]	[220,201]	2	hSpCas9	negative selection	1195887
52950744	52950767	12	+	26627737	RPE1	viability after 15 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.8813755248964917	[623]	[343,306]	5	hSpCas9	negative selection	1278202
52950744	52950767	12	+	26627737	RPE1	viability after 18 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.915707688889465	[623]	[220,420]	5	hSpCas9	negative selection	1360517
52950744	52950767	12	+	26627737	HeLa	viability after 8 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-1.2110990451782113	[653]	[172,175,36]	-8	hSpCas9	negative selection	1442832
52950744	52950767	12	+	26627737	HeLa	viability after 12 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.42572150406058934	[653]	[138,208,252]	-4	hSpCas9	negative selection	1525147
52950744	52950767	12	+	26627737	HeLa	viability after 15 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.08904876454758004	[653]	[229,248,273]	0	hSpCas9	negative selection	1607462
52950744	52950767	12	+	26627737	HeLa	viability after 18 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.09995033017815713	[653]	[145,211,273]	-1	hSpCas9	negative selection	1689777
52950744	52950767	12	+	26627737	HCT116	viability after 6 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.4946090040050438	[986]	[278,16]	-3	hSpCas9	negative selection	1772092
52950744	52950767	12	+	26627737	HCT116	viability after 8 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	1.0108295452446892	[263]	[263,248,364]	8	hSpCas9	negative selection	1854407
52950744	52950767	12	+	26627737	HCT116	viability after 9 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.5570581279909513	[986]	[475,317]	4	hSpCas9	negative selection	1936722
52950744	52950767	12	+	26627737	HCT116	viability after 12 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.7144700842847169	[263]	[211,254,217]	6	hSpCas9	negative selection	2019037
52950744	52950767	12	+	26627737	HCT116	viability after 15 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.7893731862063358	[263]	[305,267,217]	7	hSpCas9	negative selection	2101352
52950744	52950767	12	+	26627737	HCT116	viability after 18 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	1.1374418148716772	[263]	[244,323,269]	8	hSpCas9	negative selection	2183667
52949357	52949380	12	+	24336569	HL60	viability	GGCCTGGCCACCGGGATAGCCGG	KRT18	ENSG00000111057	0.4458415519520562	[501]	[1446]	4	hSpCas9	negative selection	2274277
52949569	52949592	12	+	24336569	HL60	viability	CATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.48355955303892906	[509]	[1508]	4	hSpCas9	negative selection	2274278
52950324	52950347	12	-	24336569	HL60	viability	CCACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.6424287443813128	[938]	[1272]	-5	hSpCas9	negative selection	2274279
52950744	52950767	12	+	24336569	HL60	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.10041603415076938	[907]	[2059]	1	hSpCas9	negative selection	2274280
52950824	52950847	12	-	24336569	HL60	viability	CAGCTGCAGTCGTGTGATATTGG	KRT18	ENSG00000111057	0.32876132605991687	[487]	[1296]	3	hSpCas9	negative selection	2274281
52951624	52951647	12	+	24336569	HL60	viability	AGACAAGTACTGGTCTCAGCAGG	KRT18	ENSG00000111057	0.5702835765930541	[597]	[1878]	5	hSpCas9	negative selection	2274282
52951835	52951858	12	+	24336569	HL60	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.4287917770860833	[250]	[714]	4	hSpCas9	negative selection	2274283
52951843	52951866	12	-	24336569	HL60	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-2.9045863385448167	[367]	[103]	-9	hSpCas9	negative selection	2274284
52952202	52952225	12	-	24336569	HL60	viability	TCTGTGCCAGCTCTGACTCAAGG	KRT18	ENSG00000111057	-0.29651454662417615	[342]	[590]	-3	hSpCas9	negative selection	2274285
52949357	52949380	12	+	24336569	KBM7	viability	GGCCTGGCCACCGGGATAGCCGG	KRT18	ENSG00000111057	0.7773871684513918	[399]	[1869]	7	hSpCas9	negative selection	2341454
52949569	52949592	12	+	24336569	KBM7	viability	CATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.5431429898631068	[350]	[1394]	5	hSpCas9	negative selection	2341455
52950324	52950347	12	-	24336569	KBM7	viability	CCACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	0.06768964215028506	[621]	[1777]	0	hSpCas9	negative selection	2341456
52950744	52950767	12	+	24336569	KBM7	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.3642177687089633	[890]	[1887]	-3	hSpCas9	negative selection	2341457
52950824	52950847	12	-	24336569	KBM7	viability	CAGCTGCAGTCGTGTGATATTGG	KRT18	ENSG00000111057	0.24687245175261202	[519]	[1682]	2	hSpCas9	negative selection	2341458
52951624	52951647	12	+	24336569	KBM7	viability	AGACAAGTACTGGTCTCAGCAGG	KRT18	ENSG00000111057	0.829182582290345	[583]	[2829]	7	hSpCas9	negative selection	2341459
52951835	52951858	12	+	24336569	KBM7	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.47128404072571206	[383]	[1451]	4	hSpCas9	negative selection	2341460
52951843	52951866	12	-	24336569	KBM7	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	1.4813377053896346	[38]	[296]	9	hSpCas9	negative selection	2341461
52952202	52952225	12	-	24336569	KBM7	viability	TCTGTGCCAGCTCTGACTCAAGG	KRT18	ENSG00000111057	0.1546237542611053	[304]	[925]	1	hSpCas9	negative selection	2341462
52948912	52948935	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGAAACGGGGTGGCCAACCGGG	KRT18	ENSG00000111057	-0.8105733122669183	[2,34]	[0,2]	-4	dCas9-VP64	positive selection	2383492
52948894	52948917	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTGCTGTCCGTGTCCATGCCCGG	KRT18	ENSG00000111057	0.5914925126328131	[29,30]	[4,14]	2	dCas9-VP64	positive selection	2383493
52948864	52948887	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCCCTCGAGGCTGCTTTCAGG	KRT18	ENSG00000111057	-0.43362038669303393	[433,566]	[125,32]	-2	dCas9-VP64	positive selection	2383494
52950008	52950031	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	CATTTTTTCCCTAGTGCACCTGG	KRT18	ENSG00000111057	-0.23071616703423903	[232,558]	[103,42]	-1	dCas9-VP64	positive selection	2415907
52949961	52949984	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GATTGGCTCCTCCCAAAGGAAGG	KRT18	ENSG00000111057	0.7532571344893788	[52,63]	[31,9]	3	dCas9-VP64	positive selection	2415908
52949938	52949961	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCATCTAGGAGTAAACAAGAGG	KRT18	ENSG00000111057	-0.42404272739291565	[121,176]	[8,40]	-2	dCas9-VP64	positive selection	2415909
52948912	52948935	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGAAACGGGGTGGCCAACCGGG	KRT18	ENSG00000111057	-0.7824306083897727	[83,32]	[17,3]	-7	dCas9-VP64	positive selection	2478747
52948894	52948917	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTGCTGTCCGTGTCCATGCCCGG	KRT18	ENSG00000111057	-0.9367281194198496	[207,115]	[33,21]	-8	dCas9-VP64	positive selection	2478748
52948864	52948887	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCCCTCGAGGCTGCTTTCAGG	KRT18	ENSG00000111057	2.092161444839282	[137,90]	[249,75]	8	dCas9-VP64	positive selection	2478749
52950008	52950031	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	CATTTTTTCCCTAGTGCACCTGG	KRT18	ENSG00000111057	-0.3078468545541715	[258,219]	[96,30]	-3	dCas9-VP64	positive selection	2511162
52949961	52949984	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GATTGGCTCCTCCCAAAGGAAGG	KRT18	ENSG00000111057	-0.1747245818285592	[24,63]	[6,16]	-2	dCas9-VP64	positive selection	2511163
52949938	52949961	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCATCTAGGAGTAAACAAGAGG	KRT18	ENSG00000111057	-0.84579848499384	[101,209]	[40,14]	-7	dCas9-VP64	positive selection	2511164
52950824	52950847	12	-	27260157	DLD1	viability	CAGCTGCAGTCGTGTGATATTGG	KRT18	ENSG00000111057	-0.225252478561027	[]	[]	-2	hSpCas9	negative selection	2575593
52949357	52949380	12	+	27260157	DLD1	viability	GGCCTGGCCACCGGGATAGCCGG	KRT18	ENSG00000111057	-0.299994906637561	[]	[]	-2	hSpCas9	negative selection	2576570
52952109	52952132	12	+	27260157	DLD1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.420307673612074	[]	[]	7	hSpCas9	negative selection	2577717
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579326
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579327
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579328
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579329
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579330
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579331
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579332
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579333
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579334
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579335
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579336
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579337
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579338
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579339
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579340
52950744	52950767	12	+	27260157	DLD1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.49765571047297	[]	[]	-4	hSpCas9	negative selection	2579341
52950324	52950347	12	-	27260157	DLD1	viability	CCACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.884692448382512	[]	[]	-6	hSpCas9	negative selection	2604512
52951624	52951647	12	+	27260157	DLD1	viability	AGACAAGTACTGGTCTCAGCAGG	KRT18	ENSG00000111057	-0.999994931421342	[]	[]	-7	hSpCas9	negative selection	2608042
52951843	52951866	12	-	27260157	DLD1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.74576525163109	[]	[]	8	hSpCas9	negative selection	2610334
52950398	52950421	12	+	27260157	DLD1	viability	ACTTTAGAGTCAAGTAAGTTTGG	KRT18	ENSG00000111057	0.737065641072413	[]	[]	8	hSpCas9	negative selection	2611653
52950735	52950758	12	-	27260157	DLD1	viability	TCTCATACCTATAGGAGTGGAGG	KRT18	ENSG00000111057	-0.899503737321989	[]	[]	-6	hSpCas9	negative selection	2613274
52951835	52951858	12	+	27260157	DLD1	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.659449581272543	[]	[]	8	hSpCas9	negative selection	2614792
52952202	52952225	12	-	27260157	DLD1	viability	TCTGTGCCAGCTCTGACTCAAGG	KRT18	ENSG00000111057	-0.777893506466804	[]	[]	-6	hSpCas9	negative selection	2615564
52950825	52950848	12	+	27260157	DLD1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.277285150140334	[]	[]	-2	hSpCas9	negative selection	2620808
52952330	52952353	12	+	27260157	DLD1	viability	GCGAGGACTTTAAGTGAGTGGGG	KRT18	ENSG00000111057	0.885841480321928	[]	[]	9	hSpCas9	negative selection	2621218
52952100	52952123	12	+	27260157	DLD1	viability	CCTCTCTGTGCCCCTGCAGAAGG	KRT18	ENSG00000111057	-0.772827187271563	[]	[]	-6	hSpCas9	negative selection	2622734
52952329	52952352	12	+	27260157	DLD1	viability	GGCGAGGACTTTAAGTGAGTGGG	KRT18	ENSG00000111057	-1.13563591753072	[]	[]	-7	hSpCas9	negative selection	2644864
52950728	52950751	12	+	27260157	DLD1	viability	CTGATCACCTCCACTCCTATAGG	KRT18	ENSG00000111057	-0.965244866661276	[]	[]	-7	hSpCas9	negative selection	2648849
52949569	52949592	12	+	27260157	DLD1	viability	CATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.611231007148568	[]	[]	8	hSpCas9	negative selection	2649216
52950824	52950847	12	-	27260157	HT1080	viability	CAGCTGCAGTCGTGTGATATTGG	KRT18	ENSG00000111057	0.538354203465767	[]	[]	5	hSpCas9	negative selection	2651723
52949357	52949380	12	+	27260157	HT1080	viability	GGCCTGGCCACCGGGATAGCCGG	KRT18	ENSG00000111057	0.369549877610441	[]	[]	3	hSpCas9	negative selection	2652700
52952109	52952132	12	+	27260157	HT1080	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	-0.121399714535413	[]	[]	0	hSpCas9	negative selection	2653847
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655456
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655457
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655458
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655459
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655460
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655461
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655462
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655463
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655464
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655465
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655466
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655467
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655468
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655469
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655470
52950744	52950767	12	+	27260157	HT1080	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43729458080439	[]	[]	4	hSpCas9	negative selection	2655471
52950324	52950347	12	-	27260157	HT1080	viability	CCACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.422987817715157	[]	[]	-7	hSpCas9	negative selection	2680642
52951624	52951647	12	+	27260157	HT1080	viability	AGACAAGTACTGGTCTCAGCAGG	KRT18	ENSG00000111057	0.201880887976119	[]	[]	2	hSpCas9	negative selection	2684172
52951843	52951866	12	-	27260157	HT1080	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.125703099238313	[]	[]	0	hSpCas9	negative selection	2686464
52950398	52950421	12	+	27260157	HT1080	viability	ACTTTAGAGTCAAGTAAGTTTGG	KRT18	ENSG00000111057	0.100343144691906	[]	[]	1	hSpCas9	negative selection	2687783
52950735	52950758	12	-	27260157	HT1080	viability	TCTCATACCTATAGGAGTGGAGG	KRT18	ENSG00000111057	0.266603204525997	[]	[]	2	hSpCas9	negative selection	2689404
52951835	52951858	12	+	27260157	HT1080	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.840472681061736	[]	[]	7	hSpCas9	negative selection	2690922
52952202	52952225	12	-	27260157	HT1080	viability	TCTGTGCCAGCTCTGACTCAAGG	KRT18	ENSG00000111057	-0.221439650495101	[]	[]	0	hSpCas9	negative selection	2691694
52950825	52950848	12	+	27260157	HT1080	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.273446063277315	[]	[]	2	hSpCas9	negative selection	2696938
52952330	52952353	12	+	27260157	HT1080	viability	GCGAGGACTTTAAGTGAGTGGGG	KRT18	ENSG00000111057	0.945382022448618	[]	[]	7	hSpCas9	negative selection	2697348
52952100	52952123	12	+	27260157	HT1080	viability	CCTCTCTGTGCCCCTGCAGAAGG	KRT18	ENSG00000111057	-0.525642075823862	[]	[]	-7	hSpCas9	negative selection	2698864
52952329	52952352	12	+	27260157	HT1080	viability	GGCGAGGACTTTAAGTGAGTGGG	KRT18	ENSG00000111057	0.66908005302185	[]	[]	6	hSpCas9	negative selection	2720994
52950728	52950751	12	+	27260157	HT1080	viability	CTGATCACCTCCACTCCTATAGG	KRT18	ENSG00000111057	0.740043189119744	[]	[]	6	hSpCas9	negative selection	2724979
52949569	52949592	12	+	27260157	HT1080	viability	CATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.610057915598287	[]	[]	5	hSpCas9	negative selection	2725346
52950824	52950847	12	-	27260157	MKN45	viability	CAGCTGCAGTCGTGTGATATTGG	KRT18	ENSG00000111057	1.24096401522448	[]	[]	9	hSpCas9	negative selection	2727853
52949357	52949380	12	+	27260157	MKN45	viability	GGCCTGGCCACCGGGATAGCCGG	KRT18	ENSG00000111057	-0.471253491729369	[]	[]	-6	hSpCas9	negative selection	2728830
52952109	52952132	12	+	27260157	MKN45	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.190172325281556	[]	[]	5	hSpCas9	negative selection	2729977
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731586
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731587
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731588
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731589
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731590
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731591
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731592
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731593
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731594
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731595
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731596
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731597
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731598
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731599
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731600
52950744	52950767	12	+	27260157	MKN45	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.720470705536763	[]	[]	-7	hSpCas9	negative selection	2731601
52950324	52950347	12	-	27260157	MKN45	viability	CCACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-1.06720987441576	[]	[]	-8	hSpCas9	negative selection	2756772
52951624	52951647	12	+	27260157	MKN45	viability	AGACAAGTACTGGTCTCAGCAGG	KRT18	ENSG00000111057	-1.3604653674472	[]	[]	-8	hSpCas9	negative selection	2760302
52951843	52951866	12	-	27260157	MKN45	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-1.01735637623485	[]	[]	-8	hSpCas9	negative selection	2762594
52950398	52950421	12	+	27260157	MKN45	viability	ACTTTAGAGTCAAGTAAGTTTGG	KRT18	ENSG00000111057	0.249154959669125	[]	[]	5	hSpCas9	negative selection	2763913
52950735	52950758	12	-	27260157	MKN45	viability	TCTCATACCTATAGGAGTGGAGG	KRT18	ENSG00000111057	-1.11610093469594	[]	[]	-8	hSpCas9	negative selection	2765534
52951835	52951858	12	+	27260157	MKN45	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-1.28826802846723	[]	[]	-8	hSpCas9	negative selection	2767052
52952202	52952225	12	-	27260157	MKN45	viability	TCTGTGCCAGCTCTGACTCAAGG	KRT18	ENSG00000111057	-2.95141013547077	[]	[]	-9	hSpCas9	negative selection	2767824
52950825	52950848	12	+	27260157	MKN45	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.733097242895181	[]	[]	7	hSpCas9	negative selection	2773068
52952330	52952353	12	+	27260157	MKN45	viability	GCGAGGACTTTAAGTGAGTGGGG	KRT18	ENSG00000111057	0.36631429704562	[]	[]	6	hSpCas9	negative selection	2773478
52952100	52952123	12	+	27260157	MKN45	viability	CCTCTCTGTGCCCCTGCAGAAGG	KRT18	ENSG00000111057	-1.00118734274685	[]	[]	-8	hSpCas9	negative selection	2774994
52952329	52952352	12	+	27260157	MKN45	viability	GGCGAGGACTTTAAGTGAGTGGG	KRT18	ENSG00000111057	-1.24670637684872	[]	[]	-8	hSpCas9	negative selection	2797124
52950728	52950751	12	+	27260157	MKN45	viability	CTGATCACCTCCACTCCTATAGG	KRT18	ENSG00000111057	-0.840706037682106	[]	[]	-7	hSpCas9	negative selection	2801109
52949569	52949592	12	+	27260157	MKN45	viability	CATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.979341991477214	[]	[]	8	hSpCas9	negative selection	2801476
52950824	52950847	12	-	27260157	RKO	viability	CAGCTGCAGTCGTGTGATATTGG	KRT18	ENSG00000111057	0.875869388137188	[]	[]	8	hSpCas9	negative selection	2803983
52949357	52949380	12	+	27260157	RKO	viability	GGCCTGGCCACCGGGATAGCCGG	KRT18	ENSG00000111057	0.216214232388135	[]	[]	1	hSpCas9	negative selection	2804960
52952109	52952132	12	+	27260157	RKO	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.450256047917544	[]	[]	2	hSpCas9	negative selection	2806107
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807716
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807717
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807718
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807719
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807720
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807721
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807722
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807723
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807724
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807725
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807726
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807727
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807728
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807729
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807730
52950744	52950767	12	+	27260157	RKO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0689455997908606	[]	[]	0	hSpCas9	negative selection	2807731
52950324	52950347	12	-	27260157	RKO	viability	CCACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-1.30572919415985	[]	[]	-8	hSpCas9	negative selection	2832902
52951624	52951647	12	+	27260157	RKO	viability	AGACAAGTACTGGTCTCAGCAGG	KRT18	ENSG00000111057	-0.131405060092782	[]	[]	0	hSpCas9	negative selection	2836432
52951843	52951866	12	-	27260157	RKO	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.848780322483561	[]	[]	-7	hSpCas9	negative selection	2838724
52950398	52950421	12	+	27260157	RKO	viability	ACTTTAGAGTCAAGTAAGTTTGG	KRT18	ENSG00000111057	0.616097741815973	[]	[]	3	hSpCas9	negative selection	2840043
52950735	52950758	12	-	27260157	RKO	viability	TCTCATACCTATAGGAGTGGAGG	KRT18	ENSG00000111057	-1.43274638182071	[]	[]	-8	hSpCas9	negative selection	2841664
52951835	52951858	12	+	27260157	RKO	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.484777707421904	[]	[]	2	hSpCas9	negative selection	2843182
52952202	52952225	12	-	27260157	RKO	viability	TCTGTGCCAGCTCTGACTCAAGG	KRT18	ENSG00000111057	-0.265146822042262	[]	[]	-1	hSpCas9	negative selection	2843954
52950825	52950848	12	+	27260157	RKO	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.903307388439808	[]	[]	8	hSpCas9	negative selection	2849198
52952330	52952353	12	+	27260157	RKO	viability	GCGAGGACTTTAAGTGAGTGGGG	KRT18	ENSG00000111057	0.0781787018904585	[]	[]	0	hSpCas9	negative selection	2849608
52952100	52952123	12	+	27260157	RKO	viability	CCTCTCTGTGCCCCTGCAGAAGG	KRT18	ENSG00000111057	-1.07414308024195	[]	[]	-8	hSpCas9	negative selection	2851124
52952329	52952352	12	+	27260157	RKO	viability	GGCGAGGACTTTAAGTGAGTGGG	KRT18	ENSG00000111057	-1.77962288826416	[]	[]	-9	hSpCas9	negative selection	2873254
52950728	52950751	12	+	27260157	RKO	viability	CTGATCACCTCCACTCCTATAGG	KRT18	ENSG00000111057	0.275866306220264	[]	[]	1	hSpCas9	negative selection	2877239
52949569	52949592	12	+	27260157	RKO	viability	CATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	1.00410870230622	[]	[]	9	hSpCas9	negative selection	2877606
52950824	52950847	12	-	27260157	SF268	viability	CAGCTGCAGTCGTGTGATATTGG	KRT18	ENSG00000111057	0.828146437758277	[]	[]	8	hSpCas9	negative selection	2880113
52949357	52949380	12	+	27260157	SF268	viability	GGCCTGGCCACCGGGATAGCCGG	KRT18	ENSG00000111057	-0.501386303069256	[]	[]	-4	hSpCas9	negative selection	2881090
52952109	52952132	12	+	27260157	SF268	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.383566421433173	[]	[]	4	hSpCas9	negative selection	2882237
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883846
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883847
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883848
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883849
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883850
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883851
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883852
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883853
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883854
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883855
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883856
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883857
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883858
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883859
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883860
52950744	52950767	12	+	27260157	SF268	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.610640741713438	[]	[]	-5	hSpCas9	negative selection	2883861
52950324	52950347	12	-	27260157	SF268	viability	CCACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-1.66892208601558	[]	[]	-8	hSpCas9	negative selection	2909032
52951624	52951647	12	+	27260157	SF268	viability	AGACAAGTACTGGTCTCAGCAGG	KRT18	ENSG00000111057	-0.16585272705132	[]	[]	-1	hSpCas9	negative selection	2912562
52951843	52951866	12	-	27260157	SF268	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.160566120979931	[]	[]	0	hSpCas9	negative selection	2914854
52950398	52950421	12	+	27260157	SF268	viability	ACTTTAGAGTCAAGTAAGTTTGG	KRT18	ENSG00000111057	-0.256003970270543	[]	[]	-2	hSpCas9	negative selection	2916173
52950735	52950758	12	-	27260157	SF268	viability	TCTCATACCTATAGGAGTGGAGG	KRT18	ENSG00000111057	-1.27399592977118	[]	[]	-7	hSpCas9	negative selection	2917794
52951835	52951858	12	+	27260157	SF268	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.0667381056734462	[]	[]	0	hSpCas9	negative selection	2919312
52952202	52952225	12	-	27260157	SF268	viability	TCTGTGCCAGCTCTGACTCAAGG	KRT18	ENSG00000111057	-0.216991943404817	[]	[]	-2	hSpCas9	negative selection	2920084
52950825	52950848	12	+	27260157	SF268	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.221306547289439	[]	[]	3	hSpCas9	negative selection	2925328
52952330	52952353	12	+	27260157	SF268	viability	GCGAGGACTTTAAGTGAGTGGGG	KRT18	ENSG00000111057	0.0239084610648185	[]	[]	0	hSpCas9	negative selection	2925738
52952100	52952123	12	+	27260157	SF268	viability	CCTCTCTGTGCCCCTGCAGAAGG	KRT18	ENSG00000111057	-0.677574209472096	[]	[]	-5	hSpCas9	negative selection	2927254
52952329	52952352	12	+	27260157	SF268	viability	GGCGAGGACTTTAAGTGAGTGGG	KRT18	ENSG00000111057	0.250833916019064	[]	[]	4	hSpCas9	negative selection	2949384
52950728	52950751	12	+	27260157	SF268	viability	CTGATCACCTCCACTCCTATAGG	KRT18	ENSG00000111057	-0.0587290962081909	[]	[]	0	hSpCas9	negative selection	2953369
52949569	52949592	12	+	27260157	SF268	viability	CATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	1.03761048763773	[]	[]	9	hSpCas9	negative selection	2953736
52949364	52949387	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGACCCCCGGCTATCCCGGTGG	KRT18	ENSG00000111057	-0.641009886339745	[3,2]	[1,1]	-7	hSpCas9	positive selection	2998133
52949426	52949449	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAAGCCTGAACGACCGCCTGG	KRT18	ENSG00000111057	-0.21872824622014278	[4,4]	[4,1]	-3	hSpCas9	positive selection	2998134
52950841	52950864	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCTGGAGACAGAGATCGAGG	KRT18	ENSG00000111057	0.42342760636749643	[0,1]	[1,2]	8	hSpCas9	positive selection	2998135
52949440	52949463	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTCCAGGTAAGAGGCCAGGCGG	KRT18	ENSG00000111057	-1.2269827032510827	[2,2]	[0,0]	-9	hSpCas9	positive selection	2998136
52949364	52949387	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGACCCCCGGCTATCCCGGTGG	KRT18	ENSG00000111057	-0.7851423584883139	[3,3]	[2,0]	-9	hSpCas9	positive selection	3065991
52949426	52949449	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAAGCCTGAACGACCGCCTGG	KRT18	ENSG00000111057	0.0525678407182365	[4,4]	[4,2]	0	hSpCas9	positive selection	3065992
52950841	52950864	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCTGGAGACAGAGATCGAGG	KRT18	ENSG00000111057	0.26376227028339205	[0,0]	[0,1]	4	hSpCas9	positive selection	3065993
52949440	52949463	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTCCAGGTAAGAGGCCAGGCGG	KRT18	ENSG00000111057	-0.48956337812088824	[2,2]	[1,0]	-7	hSpCas9	positive selection	3065994
52950324	52950347		+	24336571	A375	resistance to PLX after 7 days	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-0.04926782026522081	[6,7]	[6,7]	-1	hSpCas9	positive selection	3123730
52951835	52951858		+	24336571	A375	resistance to PLX after 7 days	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.07514984632217869	[9,10]	[9,11]	2	hSpCas9	positive selection	3123731
52951843	52951866		-	24336571	A375	resistance to PLX after 7 days	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.016527178123984854	[4,5]	[3,5]	0	hSpCas9	positive selection	3123732
52950324	52950347		+	24336571	A375	resistance to PLX after 14 days	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	0.5977449999082929	[5,4]	[4,1]	5	hSpCas9	positive selection	3181523
52951835	52951858		+	24336571	A375	resistance to PLX after 14 days	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	2.0185953293455503	[5,6]	[10,13]	9	hSpCas9	positive selection	3181524
52951843	52951866		-	24336571	A375	resistance to PLX after 14 days	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	1.200917607934496	[4,2]	[2,4]	8	hSpCas9	positive selection	3181525
52950324	52950347		+	24336571	A375	viability after 7 days	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.5260535666434585	[23]	[6,7]	-9	hSpCas9	negative selection	3239316
52951835	52951858		+	24336571	A375	viability after 7 days	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.08136884765395347	[10]	[9,10]	1	hSpCas9	negative selection	3239317
52951843	52951866		-	24336571	A375	viability after 7 days	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-1.310342788506176	[13]	[4,5]	-9	hSpCas9	negative selection	3239318
52950324	52950347		+	24336571	A375	viability after 14 days	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-2.051304039642885	[23]	[5,4]	-9	hSpCas9	negative selection	3297109
52951835	52951858		+	24336571	A375	viability after 14 days	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.5919157559743002	[10]	[5,6]	-6	hSpCas9	negative selection	3297110
52951843	52951866		-	24336571	A375	viability after 14 days	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-1.6729740119648053	[13]	[4,2]	-9	hSpCas9	negative selection	3297111
52951835	52951858	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.7815927804794374	[88,88]	[0,0]	4	hSpCas9	positive selection	3376255
52952109	52952132	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.5849008694743394	[101,101]	[0,0]	3	hSpCas9	positive selection	3376256
52952166	52952189	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.10022579317224871	[163,163]	[0,0]	0	hSpCas9	positive selection	3376257
52949364	52949387	12	-	26780180	HT29	viability (Avana library 4 designs)	CAGACCCCCGGCTATCCCGGTGG	KRT18	ENSG00000111057	1.0851016524842	[]	[]	4	hSpCas9	negative selection	3435585
52949425	52949448	12	+	26780180	HT29	viability (Avana library 4 designs)	GCAAAGCCTGAACGACCGCCTGG	KRT18	ENSG00000111057	-0.693164396736518	[]	[]	-8	hSpCas9	negative selection	3435586
52950840	52950863	12	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCTGGAGACAGAGATCGAGG	KRT18	ENSG00000111057	4.59337189049537	[]	[]	9	hSpCas9	negative selection	3435587
52949440	52949463	12	-	26780180	HT29	viability (Avana library 4 designs)	TGTCCAGGTAAGAGGCCAGGCGG	KRT18	ENSG00000111057	4.27341582090522	[]	[]	9	hSpCas9	negative selection	3435588
52949440	52949463	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGTCCAGGTAAGAGGCCAGGCGG	KRT18	ENSG00000111057	-10.0415898039367	[]	[]	-7	hSpCas9	negative selection	3523225
52950840	52950863	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGGAGACAGAGATCGAGG	KRT18	ENSG00000111057	-16.2195285047104	[]	[]	-9	hSpCas9	negative selection	3523226
52949425	52949448	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAAGCCTGAACGACCGCCTGG	KRT18	ENSG00000111057	5.89296753705837	[]	[]	9	hSpCas9	negative selection	3523227
52949364	52949387	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGACCCCCGGCTATCCCGGTGG	KRT18	ENSG00000111057	2.29109005233211	[]	[]	3	hSpCas9	negative selection	3523228
52949472	52949495	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCTGGAGACCGAGAACCGGAGG	KRT18	ENSG00000111057	-8.82524767739137	[]	[]	-7	hSpCas9	negative selection	3523229
52949248	52949271	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CGCCCGGCCGGTCAGCAGCGCGG	KRT18	ENSG00000111057	6.8950722183951	[]	[]	9	hSpCas9	negative selection	3523230
52949440	52949463	12	-	26780180	A375	viability (Avana lentiGuide)	TGTCCAGGTAAGAGGCCAGGCGG	KRT18	ENSG00000111057	13.0900372950172	[]	[]	7	hSpCas9	negative selection	3631884
52950840	52950863	12	+	26780180	A375	viability (Avana lentiGuide)	GCAGCTGGAGACAGAGATCGAGG	KRT18	ENSG00000111057	31.7154121616269	[]	[]	9	hSpCas9	negative selection	3631885
52949425	52949448	12	+	26780180	A375	viability (Avana lentiGuide)	GCAAAGCCTGAACGACCGCCTGG	KRT18	ENSG00000111057	-0.894804885026802	[]	[]	-1	hSpCas9	negative selection	3631886
52949364	52949387	12	-	26780180	A375	viability (Avana lentiGuide)	CAGACCCCCGGCTATCCCGGTGG	KRT18	ENSG00000111057	-2.49767553946978	[]	[]	-4	hSpCas9	negative selection	3631887
52949472	52949495	12	+	26780180	A375	viability (Avana lentiGuide)	GCCTGGAGACCGAGAACCGGAGG	KRT18	ENSG00000111057	26.2194267259126	[]	[]	9	hSpCas9	negative selection	3631888
52949248	52949271	12	+	26780180	A375	viability (Avana lentiGuide)	CGCCCGGCCGGTCAGCAGCGCGG	KRT18	ENSG00000111057	-1.26815415178997	[]	[]	-2	hSpCas9	negative selection	3631889
52949440	52949463	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTCCAGGTAAGAGGCCAGGCGG	KRT18	ENSG00000111057	-0.6963177013905557	[4]	[1,2]	-7	hSpCas9	positive selection	3740543
52950840	52950863	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGGAGACAGAGATCGAGG	KRT18	ENSG00000111057	-1.1588449024780298	[4]	[2,0]	-9	hSpCas9	positive selection	3740544
52949425	52949448	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAAGCCTGAACGACCGCCTGG	KRT18	ENSG00000111057	0.32076716453253007	[4]	[6,5]	8	hSpCas9	positive selection	3740545
52949364	52949387	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGACCCCCGGCTATCCCGGTGG	KRT18	ENSG00000111057	0.2539090943583505	[4]	[5,5]	7	hSpCas9	positive selection	3740546
52949472	52949495	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCTGGAGACCGAGAACCGGAGG	KRT18	ENSG00000111057	-0.6867611055131507	[3]	[2,1]	-7	hSpCas9	positive selection	3740547
52949248	52949271	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CGCCCGGCCGGTCAGCAGCGCGG	KRT18	ENSG00000111057	0.08854752398324423	[3]	[3,3]	2	hSpCas9	positive selection	3740548
52949440	52949463	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTCCAGGTAAGAGGCCAGGCGG	KRT18	ENSG00000111057	-0.6467046973464096	[5]	[0,4]	-7	hSpCas9	positive selection	3849150
52950840	52950863	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGGAGACAGAGATCGAGG	KRT18	ENSG00000111057	-1.8487999145446494	[4]	[0,0]	-9	hSpCas9	positive selection	3849151
52949425	52949448	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAAGCCTGAACGACCGCCTGG	KRT18	ENSG00000111057	0.2407822520769966	[6]	[6,6]	6	hSpCas9	positive selection	3849152
52949364	52949387	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGACCCCCGGCTATCCCGGTGG	KRT18	ENSG00000111057	0.36801661049247664	[4]	[4,5]	9	hSpCas9	positive selection	3849153
52949472	52949495	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCTGGAGACCGAGAACCGGAGG	KRT18	ENSG00000111057	-1.34265681890423	[4]	[1,0]	-9	hSpCas9	positive selection	3849154
52949248	52949271	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CGCCCGGCCGGTCAGCAGCGCGG	KRT18	ENSG00000111057	-0.9147110132429748	[4]	[1,1]	-8	hSpCas9	positive selection	3849155
52950825	52950848	12	+	26780180	A375	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.871389560730744	[]	[]	3	hSpCas9	negative selection	3955234
52951835	52951858	12	+	26780180	A375	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.752220939992106	[]	[]	2	hSpCas9	negative selection	3955235
52952166	52952189	12	-	26780180	A375	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	1.74888832314412	[]	[]	9	hSpCas9	negative selection	3955236
52950744	52950767	12	+	26780180	A375	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.546833547034198	[]	[]	1	hSpCas9	negative selection	3955237
52952109	52952132	12	+	26780180	A375	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.281362399523304	[]	[]	0	hSpCas9	negative selection	3955238
52951843	52951866	12	-	26780180	A375	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	1.29896132032574	[]	[]	7	hSpCas9	negative selection	3955239
52950825	52950848	12	+	26780180	HT29	viability (GeCKOv2 library)	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.943715784675794	[]	[]	4	hSpCas9	negative selection	4063200
52951835	52951858	12	+	26780180	HT29	viability (GeCKOv2 library)	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	1.79847877556319	[]	[]	8	hSpCas9	negative selection	4063201
52952166	52952189	12	-	26780180	HT29	viability (GeCKOv2 library)	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	1.73839027473465	[]	[]	8	hSpCas9	negative selection	4063202
52950744	52950767	12	+	26780180	HT29	viability (GeCKOv2 library)	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	2.15797388356718	[]	[]	9	hSpCas9	negative selection	4063203
52952109	52952132	12	+	26780180	HT29	viability (GeCKOv2 library)	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.335102924946883	[]	[]	0	hSpCas9	negative selection	4063204
52951843	52951866	12	-	26780180	HT29	viability (GeCKOv2 library)	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.868737548734197	[]	[]	3	hSpCas9	negative selection	4063205
52950324	52950347	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	0.11700130061162971	[2]	[2,1]	3	hSpCas9	positive selection	4147694
52951835	52951858	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.19799462830819228	[3]	[1,3]	5	hSpCas9	positive selection	4147695
52951843	52951866	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.17832361234663302	[2]	[1,1]	-4	hSpCas9	positive selection	4147696
52950324	52950347	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-0.14779060137185307	[2]	[0,2,0,0]	-2	hSpCas9	positive selection	4211716
52951835	52951858	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.5865693656001286	[3]	[0,1,1,3]	4	hSpCas9	positive selection	4211717
52951843	52951866	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.49847114736014264	[2]	[2,2,2,0]	3	hSpCas9	positive selection	4211718
52951843	52951866	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.050591919988075884	[2]	[2,0]	1	hSpCas9	positive selection	4279113
52950744	52950767	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.43604120120997103	[2]	[0,1]	-7	hSpCas9	positive selection	4279114
52950825	52950848	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.09971622125102475	[1]	[1,0]	-2	hSpCas9	positive selection	4279115
52951835	52951858	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.1072683756597218	[2]	[2,1]	2	hSpCas9	positive selection	4343368
52952109	52952132	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.0928539122159126	[2]	[2,1]	2	hSpCas9	positive selection	4343369
52952166	52952189	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.01589014291463834	[3]	[2,2]	0	hSpCas9	positive selection	4343370
52949359	52949381	12	-	27760321	OCIAML3	viability	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	0.7215630475689425	[1011,786]	[1022,1319]	8	hSpCas9	negative selection	4413069
52949570	52949592	12	+	27760321	OCIAML3	viability	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.2703532649833389	[819,621]	[520,874]	3	hSpCas9	negative selection	4413070
52950324	52950346	12	-	27760321	OCIAML3	viability	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.37604955323357564	[380,288]	[122,300]	-4	hSpCas9	negative selection	4413071
52950826	52950848	12	+	27760321	OCIAML3	viability	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.3710324815062592	[619,478]	[513,600]	4	hSpCas9	negative selection	4413072
52949359	52949381	12	-	27760321	OCIAML2	viability	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	0.6835846307120612	[1011,786]	[1037,1321]	8	hSpCas9	negative selection	4496532
52949570	52949592	12	+	27760321	OCIAML2	viability	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.22735859883335485	[819,621]	[644,719]	3	hSpCas9	negative selection	4496533
52950324	52950346	12	-	27760321	OCIAML2	viability	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.14634689657361138	[380,288]	[235,251]	-2	hSpCas9	negative selection	4496534
52950826	52950848	12	+	27760321	OCIAML2	viability	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.6327156596941197	[619,478]	[691,673]	8	hSpCas9	negative selection	4496535
52949359	52949381	12	-	27760321	MV411	viability	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	0.8782220009887332	[1011,786]	[899,1358]	6	hSpCas9	negative selection	4579995
52949570	52949592	12	+	27760321	MV411	viability	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.3270035633456987	[819,621]	[428,836]	2	hSpCas9	negative selection	4579996
52950324	52950346	12	-	27760321	MV411	viability	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-2.050022468096157	[380,288]	[0,130]	-8	hSpCas9	negative selection	4579997
52950826	52950848	12	+	27760321	MV411	viability	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.7577567052686166	[619,478]	[714,448]	5	hSpCas9	negative selection	4579998
52949359	52949381	12	-	27760321	HL60	viability	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	0.7455710571503675	[1011,786]	[1284,1157]	8	hSpCas9	negative selection	4663458
52949570	52949592	12	+	27760321	HL60	viability	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	-0.09825119895848877	[819,621]	[505,587]	-1	hSpCas9	negative selection	4663459
52950324	52950346	12	-	27760321	HL60	viability	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.8124923148511953	[380,288]	[156,151]	-7	hSpCas9	negative selection	4663460
52950826	52950848	12	+	27760321	HL60	viability	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.6877633261135646	[619,478]	[793,636]	7	hSpCas9	negative selection	4663461
52949359	52949381	12	-	27760321	HT1080	viability	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	1.0164694390454525	[786,613]	[627,494]	5	hSpCas9	negative selection	4746921
52949570	52949592	12	+	27760321	HT1080	viability	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.07067552157788781	[621,485]	[237,224]	0	hSpCas9	negative selection	4746922
52950324	52950346	12	-	27760321	HT1080	viability	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.48828036913197936	[288,225]	[75,69]	-2	hSpCas9	negative selection	4746923
52950826	52950848	12	+	27760321	HT1080	viability	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.7049199303533528	[478,373]	[96,473]	4	hSpCas9	negative selection	4746924
52949359	52949381	12	-	27760321	HT29	viability after 7 days	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	0.6501308141940725	[786,613]	[1518,1222,1507]	8	hSpCas9	negative selection	4830384
52949570	52949592	12	+	27760321	HT29	viability after 7 days	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.16276224836395126	[621,485]	[606,834,917]	2	hSpCas9	negative selection	4830385
52950324	52950346	12	-	27760321	HT29	viability after 7 days	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.45744816503076313	[288,225]	[368,216,157]	-6	hSpCas9	negative selection	4830386
52950826	52950848	12	+	27760321	HT29	viability after 7 days	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.5110230264409952	[478,373]	[462,316,384]	-6	hSpCas9	negative selection	4830387
52949359	52949381	12	-	27760321	HT29	viability after 25 days	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	1.2888471486567707	[786,613]	[1372,1905,2699]	9	hSpCas9	negative selection	4913847
52949570	52949592	12	+	27760321	HT29	viability after 25 days	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.5944216129118478	[621,485]	[537,1035,1360]	6	hSpCas9	negative selection	4913848
52950324	52950346	12	-	27760321	HT29	viability after 25 days	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.5466794584473563	[288,225]	[331,147,105]	-5	hSpCas9	negative selection	4913849
52950826	52950848	12	+	27760321	HT29	viability after 25 days	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.16902686356977797	[478,373]	[738,234,291]	-2	hSpCas9	negative selection	4913850
52949359	52949381	12	-	27760321	HT29	viability after 22 days	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	1.2827384976805798	[786,613]	[1662,1963,2294]	9	hSpCas9	negative selection	4997310
52949570	52949592	12	+	27760321	HT29	viability after 22 days	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.4638487117807526	[621,485]	[736,1040,875]	5	hSpCas9	negative selection	4997311
52950324	52950346	12	-	27760321	HT29	viability after 22 days	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.7852074585786165	[288,225]	[186,249,79]	-6	hSpCas9	negative selection	4997312
52950826	52950848	12	+	27760321	HT29	viability after 22 days	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.2679306256955681	[478,373]	[376,479,371]	-3	hSpCas9	negative selection	4997313
52949359	52949381	12	-	27760321	HT29	viability after 19 days	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	0.9107151719035018	[786,613]	[1577,1311,1629]	8	hSpCas9	negative selection	5080773
52949570	52949592	12	+	27760321	HT29	viability after 19 days	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.5548033222690216	[621,485]	[604,694,1437]	5	hSpCas9	negative selection	5080774
52950324	52950346	12	-	27760321	HT29	viability after 19 days	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-0.8768662643487518	[288,225]	[291,46,155]	-6	hSpCas9	negative selection	5080775
52950826	52950848	12	+	27760321	HT29	viability after 19 days	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.11453867477064256	[478,373]	[519,371,684]	1	hSpCas9	negative selection	5080776
52949359	52949381	12	-	27760321	HT29	viability after 16 days	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	1.4257112990470378	[786,613]	[1923,2247,2122]	9	hSpCas9	negative selection	5164236
52949570	52949592	12	+	27760321	HT29	viability after 16 days	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.4238552234802486	[621,485]	[802,632,1060]	5	hSpCas9	negative selection	5164237
52950324	52950346	12	-	27760321	HT29	viability after 16 days	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	0.27254416119641933	[288,225]	[182,480,360]	3	hSpCas9	negative selection	5164238
52950826	52950848	12	+	27760321	HT29	viability after 16 days	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.03341340580474822	[478,373]	[509,229,668]	0	hSpCas9	negative selection	5164239
52949359	52949381	12	-	27760321	HT29	viability after 13 days	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	1.2560191040577255	[786,613]	[1854,2325,1658]	9	hSpCas9	negative selection	5247699
52949570	52949592	12	+	27760321	HT29	viability after 13 days	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.3970939125344122	[621,485]	[1030,667,839]	5	hSpCas9	negative selection	5247700
52950324	52950346	12	-	27760321	HT29	viability after 13 days	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	-1.5858144162375325	[288,225]	[86,152,60]	-8	hSpCas9	negative selection	5247701
52950826	52950848	12	+	27760321	HT29	viability after 13 days	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.02787923303636669	[478,373]	[417,548,543]	0	hSpCas9	negative selection	5247702
52949359	52949381	12	-	27760321	HT29	viability after 10 days	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	0.7420313964070369	[786,613]	[1566,1393,1425]	8	hSpCas9	negative selection	5331162
52949570	52949592	12	+	27760321	HT29	viability after 10 days	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	0.496185969892728	[621,485]	[567,1379,989]	6	hSpCas9	negative selection	5331163
52950324	52950346	12	-	27760321	HT29	viability after 10 days	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	0.22476718509531024	[288,225]	[293,628,214]	3	hSpCas9	negative selection	5331164
52950826	52950848	12	+	27760321	HT29	viability after 10 days	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.04270312752407707	[478,373]	[341,817,401]	0	hSpCas9	negative selection	5331165
52949359	52949381	12	-	27760321	MOLM13	viability	CCCGGCTATCCCGGTGGCCAGG	KRT18	ENSG00000111057	1.4978006618483233	[1011,786]	[1648,1230]	9	hSpCas9	negative selection	5414625
52949570	52949592	12	+	27760321	MOLM13	viability	ATCGAGGACCTGAGGGCTCAGG	KRT18	ENSG00000111057	-0.2843236246477998	[819,621]	[487,197]	-2	hSpCas9	negative selection	5414626
52950324	52950346	12	-	27760321	MOLM13	viability	CACAGTATTTGCGAAGATCTGG	KRT18	ENSG00000111057	1.5328154483633167	[380,288]	[1086,78]	9	hSpCas9	negative selection	5414627
52950826	52950848	12	+	27760321	MOLM13	viability	AATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.50335483663365	[619,478]	[445,427]	3	hSpCas9	negative selection	5414628
52949017	52949040	12	+	27661255	K562	viability	GGCTCCGAGCCGTCCACCTGTGG	KRT18	ENSG00000111057	0.1803240117613289	[929,1062]	[915,885]	6	dCas9-KRAB	negative selection	5489241
52949576	52949599	12	+	27661255	K562	viability	GACCTGAGGGCTCAGGTAAGGGG	KRT18	ENSG00000111057	-0.21852874348633805	[586,531]	[434,341]	-6	dCas9-KRAB	negative selection	5489242
52948875	52948898	12	-	27661255	K562	viability	GCAGGTGTTGTTGGCCCTCGAGG	KRT18	ENSG00000111057	-0.05311381496454349	[797,805]	[625,609]	-2	dCas9-KRAB	negative selection	5489243
52949119	52949142	12	-	27661255	K562	viability	GGCTTTGCGGACGACGGTGGCGG	KRT18	ENSG00000111057	0.16196682153516262	[782,905]	[816,697]	5	dCas9-KRAB	negative selection	5489244
52949826	52949849	12	+	27661255	K562	viability	GAGGAAGTGGACAGCATGGAGGG	KRT18	ENSG00000111057	0.12985270288628592	[1742,1706]	[1666,1372]	4	dCas9-KRAB	negative selection	5489377
52949851	52949874	12	+	27661255	K562	viability	GTAAGGAAAGGCCTGTAAAGAGG	KRT18	ENSG00000111057	0.02423995589739303	[1067,1251]	[971,911]	0	dCas9-KRAB	negative selection	5489378
52949648	52949671	12	-	27661255	K562	viability	GGAATGACGGAAAGAGGCAAAGG	KRT18	ENSG00000111057	0.030818959772532628	[711,698]	[637,522]	1	dCas9-KRAB	negative selection	5489380
52951843	52951866	12	-	27260156	BXPC3	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.04978268126252883	[216]	[152,199,215,399]	1	hSpCas9	negative selection	5551573
52950744	52950767	12	+	27260156	BXPC3	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.18394469773108924	[284]	[233,179,385,256]	-4	hSpCas9	negative selection	5551574
52950825	52950848	12	+	27260156	BXPC3	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.018437090745602847	[143]	[123,143,172,156]	0	hSpCas9	negative selection	5551575
52951835	52951858	12	+	27260156	BXPC3	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.09314815843094265	[348]	[307,366,332,578]	2	hSpCas9	negative selection	5615828
52952109	52952132	12	+	27260156	BXPC3	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.4443228290721946	[266]	[403,382,298,432]	8	hSpCas9	negative selection	5615829
52952166	52952189	12	-	27260156	BXPC3	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.23088553186500305	[476]	[316,425,499,472]	-5	hSpCas9	negative selection	5615830
52951843	52951866	12	-	27260156	A673	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.3155367682643203	[216]	[275,184,343,498]	7	hSpCas9	negative selection	5672824
52950744	52950767	12	+	27260156	A673	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.20449240860624307	[284]	[269,278,269,369]	-5	hSpCas9	negative selection	5672825
52950825	52950848	12	+	27260156	A673	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.01998883587358513	[143]	[214,148,126,217]	0	hSpCas9	negative selection	5672826
52951835	52951858	12	+	27260156	A673	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.008280807302620041	[348]	[493,384,392,402]	0	hSpCas9	negative selection	5737079
52952109	52952132	12	+	27260156	A673	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.35435132982318696	[266]	[483,357,434,368]	7	hSpCas9	negative selection	5737080
52952166	52952189	12	-	27260156	A673	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.35440187143078966	[476]	[421,423,527,411]	-7	hSpCas9	negative selection	5737081
52951843	52951866	12	-	27260156	A375	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.004628514301474818	[216]	[316,205,194,281]	0	hSpCas9	negative selection	5794075
52950744	52950767	12	+	27260156	A375	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.8614438634330156	[284]	[196,158,199,173]	-8	hSpCas9	negative selection	5794076
52950825	52950848	12	+	27260156	A375	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.3409949630372673	[143]	[153,159,357,175]	5	hSpCas9	negative selection	5794077
52951835	52951858	12	+	27260156	A375	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.06711559489070879	[348]	[562,296,333,487]	1	hSpCas9	negative selection	5858330
52952109	52952132	12	+	27260156	A375	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.2345458650587564	[266]	[192,304,569,385]	3	hSpCas9	negative selection	5858331
52952166	52952189	12	-	27260156	A375	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-1.1492291975461701	[476]	[250,393,176,206]	-8	hSpCas9	negative selection	5858332
52951843	52951866	12	-	27260156	COLO741	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.2845224575508388	[216]	[340,338,332]	6	hSpCas9	negative selection	5915326
52950744	52950767	12	+	27260156	COLO741	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.37443527976121393	[284]	[290,299,253]	-7	hSpCas9	negative selection	5915327
52950825	52950848	12	+	27260156	COLO741	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.20605817354902056	[143]	[123,146,200]	-4	hSpCas9	negative selection	5915328
52951835	52951858	12	+	27260156	COLO741	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.2680669657313122	[348]	[578,410,616]	5	hSpCas9	negative selection	5979581
52952109	52952132	12	+	27260156	COLO741	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.241301703887415	[266]	[376,374,450]	5	hSpCas9	negative selection	5979582
52952166	52952189	12	-	27260156	COLO741	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.7127781831988718	[476]	[317,276,504]	-9	hSpCas9	negative selection	5979583
52951843	52951866	12	-	27260156	CAL120	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.30448226922384203	[216]	[293,142,229]	-4	hSpCas9	negative selection	6036577
52950744	52950767	12	+	27260156	CAL120	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.28638824728213275	[284]	[380,222,281]	-4	hSpCas9	negative selection	6036578
52950825	52950848	12	+	27260156	CAL120	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.3642535220273737	[143]	[128,145,140]	-5	hSpCas9	negative selection	6036579
52951835	52951858	12	+	27260156	CAL120	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.04167144574486048	[348]	[523,467,361]	0	hSpCas9	negative selection	6100832
52952109	52952132	12	+	27260156	CAL120	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.24102173331747756	[266]	[267,661,231]	3	hSpCas9	negative selection	6100833
52952166	52952189	12	-	27260156	CAL120	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-1.0420334886562106	[476]	[272,335,253]	-8	hSpCas9	negative selection	6100834
52951843	52951866	12	-	27260156	CADOES1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.003175684708114801	[216]	[163,282,202,153]	0	hSpCas9	negative selection	6157828
52950744	52950767	12	+	27260156	CADOES1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-1.0855870170450386	[284]	[106,164,95,131]	-9	hSpCas9	negative selection	6157829
52950825	52950848	12	+	27260156	CADOES1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.49680697709650556	[143]	[244,130,105,276]	7	hSpCas9	negative selection	6157830
52951835	52951858	12	+	27260156	CADOES1	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.26956766251417874	[348]	[403,393,275,494]	4	hSpCas9	negative selection	6222083
52952109	52952132	12	+	27260156	CADOES1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.11223656638889767	[266]	[233,279,259,300]	2	hSpCas9	negative selection	6222084
52952166	52952189	12	-	27260156	CADOES1	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.4306341512927999	[476]	[350,313,360,288]	-6	hSpCas9	negative selection	6222085
52951843	52951866	12	-	27260156	EWS502	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.29315280563310975	[216]	[376,171,245,325]	5	hSpCas9	negative selection	6279079
52950744	52950767	12	+	27260156	EWS502	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.14483429460231323	[284]	[325,251,184,324]	-3	hSpCas9	negative selection	6279080
52950825	52950848	12	+	27260156	EWS502	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.12329377953251286	[143]	[154,255,137,107]	2	hSpCas9	negative selection	6279081
52951835	52951858	12	+	27260156	EWS502	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.06267916231488085	[348]	[300,349,525,378]	1	hSpCas9	negative selection	6343334
52952109	52952132	12	+	27260156	EWS502	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.3780544827048827	[266]	[331,423,320,394]	6	hSpCas9	negative selection	6343335
52952166	52952189	12	-	27260156	EWS502	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.520600551895475	[476]	[210,350,476,389]	-7	hSpCas9	negative selection	6343336
52951843	52951866	12	-	27260156	EW8	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.1150388214282333	[216]	[215,181,178,188]	2	hSpCas9	negative selection	6400330
52950744	52950767	12	+	27260156	EW8	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.6304780950722105	[284]	[250,164,94,105]	-8	hSpCas9	negative selection	6400331
52950825	52950848	12	+	27260156	EW8	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.010773250015540414	[143]	[184,74,94,125]	0	hSpCas9	negative selection	6400332
52951835	52951858	12	+	27260156	EW8	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.32321757720803823	[348]	[374,426,223,412]	6	hSpCas9	negative selection	6464585
52952109	52952132	12	+	27260156	EW8	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.3662303830790993	[266]	[292,312,276,233]	6	hSpCas9	negative selection	6464586
52952166	52952189	12	-	27260156	EW8	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.285687806566702	[476]	[381,264,259,376]	-5	hSpCas9	negative selection	6464587
52951843	52951866	12	-	27260156	CORL105	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.5550829394797047	[216]	[402,390,374,324]	8	hSpCas9	negative selection	6521581
52950744	52950767	12	+	27260156	CORL105	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.35717143844494526	[284]	[227,174,329,319]	-6	hSpCas9	negative selection	6521582
52950825	52950848	12	+	27260156	CORL105	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.09036161947608168	[143]	[198,84,176,177]	-2	hSpCas9	negative selection	6521583
52951835	52951858	12	+	27260156	CORL105	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.043765169315135466	[348]	[339,448,577,338]	0	hSpCas9	negative selection	6585836
52952109	52952132	12	+	27260156	CORL105	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.23280742821341405	[266]	[313,346,464,356]	4	hSpCas9	negative selection	6585837
52952166	52952189	12	-	27260156	CORL105	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.40570837255569564	[476]	[304,322,608,475]	-6	hSpCas9	negative selection	6585838
52951843	52951866	12	-	27260156	HS294T	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.20753828394837015	[216]	[40,73,107,69]	-3	hSpCas9	negative selection	6642832
52950744	52950767	12	+	27260156	HS294T	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.32444842121921763	[284]	[220,61,79,191]	4	hSpCas9	negative selection	6642833
52950825	52950848	12	+	27260156	HS294T	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.26484988928936337	[143]	[65,36,80,87]	3	hSpCas9	negative selection	6642834
52951835	52951858	12	+	27260156	HS294T	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.09655119908470694	[348]	[168,134,113,158]	1	hSpCas9	negative selection	6707087
52952109	52952132	12	+	27260156	HS294T	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.01250940671333356	[266]	[143,87,65,116]	0	hSpCas9	negative selection	6707088
52952166	52952189	12	-	27260156	HS294T	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.06633771228315188	[476]	[128,143,278,153]	-1	hSpCas9	negative selection	6707089
52951843	52951866	12	-	27260156	HCC44	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.2946090749814144	[216]	[401,252,255,298]	5	hSpCas9	negative selection	6764083
52950744	52950767	12	+	27260156	HCC44	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.10339141317332412	[284]	[392,223,339,267]	-2	hSpCas9	negative selection	6764084
52950825	52950848	12	+	27260156	HCC44	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.08977831242660006	[143]	[191,152,194,83]	-1	hSpCas9	negative selection	6764085
52951835	52951858	12	+	27260156	HCC44	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.16392800780359557	[348]	[717,326,407,350]	2	hSpCas9	negative selection	6828338
52952109	52952132	12	+	27260156	HCC44	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.26273862482865296	[266]	[383,410,197,417]	4	hSpCas9	negative selection	6828339
52952166	52952189	12	-	27260156	HCC44	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.6561593559457166	[476]	[346,288,252,465]	-7	hSpCas9	negative selection	6828340
52951843	52951866	12	-	27260156	G402	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.25468144823329786	[216]	[820,319,141,64]	3	hSpCas9	negative selection	6885334
52950744	52950767	12	+	27260156	G402	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.6080915595357396	[284]	[525,669,404,524]	7	hSpCas9	negative selection	6885335
52950825	52950848	12	+	27260156	G402	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.5100272174710518	[143]	[192,344,374,91]	6	hSpCas9	negative selection	6885336
52951835	52951858	12	+	27260156	G402	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.02631906851017085	[348]	[451,283,469,459]	0	hSpCas9	negative selection	6949589
52952109	52952132	12	+	27260156	G402	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.7004784040333952	[266]	[787,478,436,449]	8	hSpCas9	negative selection	6949590
52952166	52952189	12	-	27260156	G402	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.23533188542239475	[476]	[321,314,925,382]	-3	hSpCas9	negative selection	6949591
52951843	52951866	12	-	27260156	L33	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.0933488557171418	[216]	[232,84,138,263]	2	hSpCas9	negative selection	7006585
52950744	52950767	12	+	27260156	L33	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.02282390354233521	[284]	[361,139,127,248]	0	hSpCas9	negative selection	7006586
52950825	52950848	12	+	27260156	L33	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.24018103752453923	[143]	[156,82,99,161]	5	hSpCas9	negative selection	7006587
52951835	52951858	12	+	27260156	L33	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.17351144749731862	[348]	[324,172,282,378]	4	hSpCas9	negative selection	7070840
52952109	52952132	12	+	27260156	L33	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	-0.16684584474110464	[266]	[307,83,139,213]	-4	hSpCas9	negative selection	7070841
52952166	52952189	12	-	27260156	L33	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.24595275666613942	[476]	[422,190,223,362]	-5	hSpCas9	negative selection	7070842
52951843	52951866	12	-	27260156	K562	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.4669946019400373	[216]	[162,110,217,72]	-5	hSpCas9	negative selection	7127836
52950744	52950767	12	+	27260156	K562	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.06052842940988168	[284]	[228,122,256,340]	0	hSpCas9	negative selection	7127837
52950825	52950848	12	+	27260156	K562	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.1664028365336936	[143]	[261,127,67,125]	2	hSpCas9	negative selection	7127838
52951835	52951858	12	+	27260156	K562	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.21057794797328797	[348]	[435,477,269,270]	2	hSpCas9	negative selection	7192091
52952109	52952132	12	+	27260156	K562	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.42909359994891993	[266]	[287,257,309,402]	5	hSpCas9	negative selection	7192092
52952166	52952189	12	-	27260156	K562	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.6052527800266128	[476]	[430,144,221,314]	-6	hSpCas9	negative selection	7192093
52951843	52951866	12	-	27260156	HT29	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.917035546723328	[216]	[128,170,158,104]	-8	hSpCas9	negative selection	7249087
52950744	52950767	12	+	27260156	HT29	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-1.3925447184502815	[284]	[133,90,134,159]	-9	hSpCas9	negative selection	7249088
52950825	52950848	12	+	27260156	HT29	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.0453816903335611	[143]	[242,78,271,90]	-1	hSpCas9	negative selection	7249089
52951835	52951858	12	+	27260156	HT29	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.07811305216933867	[348]	[465,419,460,440]	1	hSpCas9	negative selection	7313342
52952109	52952132	12	+	27260156	HT29	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.3930964674312879	[266]	[503,392,516,305]	7	hSpCas9	negative selection	7313343
52952166	52952189	12	-	27260156	HT29	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.7172795497566165	[476]	[378,326,456,256]	-8	hSpCas9	negative selection	7313344
52951843	52951866	12	-	27260156	MHHES1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.3993126915865123	[216]	[268,431,226,350]	7	hSpCas9	negative selection	7370338
52950744	52950767	12	+	27260156	MHHES1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.11815444638032202	[284]	[177,410,341,252]	-2	hSpCas9	negative selection	7370339
52950825	52950848	12	+	27260156	MHHES1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.2666877230182829	[143]	[215,287,137,154]	5	hSpCas9	negative selection	7370340
52951835	52951858	12	+	27260156	MHHES1	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.11638384840114491	[348]	[483,423,308,267]	-2	hSpCas9	negative selection	7434593
52952109	52952132	12	+	27260156	MHHES1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.30170716779797646	[266]	[570,335,409,214]	5	hSpCas9	negative selection	7434594
52952166	52952189	12	-	27260156	MHHES1	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.028585354091031936	[476]	[807,536,555,285]	0	hSpCas9	negative selection	7434595
52951843	52951866	12	-	27260156	MEWO	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.5083294381804937	[216]	[303,329,234]	8	hSpCas9	negative selection	7491589
52950744	52950767	12	+	27260156	MEWO	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.16192145112140777	[284]	[314,193,220]	-4	hSpCas9	negative selection	7491590
52950825	52950848	12	+	27260156	MEWO	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.13244073862318406	[143]	[133,88,147]	-3	hSpCas9	negative selection	7491591
52951835	52951858	12	+	27260156	MEWO	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.14866592238736626	[348]	[420,405,269]	3	hSpCas9	negative selection	7555844
52952109	52952132	12	+	27260156	MEWO	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.16648876656807188	[266]	[372,267,217]	3	hSpCas9	negative selection	7555845
52952166	52952189	12	-	27260156	MEWO	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.5859377943062045	[476]	[450,221,248]	-8	hSpCas9	negative selection	7555846
52951843	52951866	12	-	27260156	LNCAPCLONEFGC	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.22382579475412379	[216]	[210,83,242,150]	-4	hSpCas9	negative selection	7612840
52950744	52950767	12	+	27260156	LNCAPCLONEFGC	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.11205922499953092	[284]	[158,386,244,156]	-2	hSpCas9	negative selection	7612841
52950825	52950848	12	+	27260156	LNCAPCLONEFGC	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.10880625812546518	[143]	[148,86,194,142]	1	hSpCas9	negative selection	7612842
52951835	52951858	12	+	27260156	LNCAPCLONEFGC	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.18568987448580326	[348]	[360,295,465,334]	3	hSpCas9	negative selection	7677095
52952109	52952132	12	+	27260156	LNCAPCLONEFGC	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.5005337141883774	[266]	[303,237,536,325]	7	hSpCas9	negative selection	7677096
52952166	52952189	12	-	27260156	LNCAPCLONEFGC	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-1.382034277761043	[476]	[109,148,197,212]	-9	hSpCas9	negative selection	7677097
52951843	52951866	12	-	27260156	PANC0327	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.18961853191439526	[216]	[285,99,162,350]	3	hSpCas9	negative selection	7734091
52950744	52950767	12	+	27260156	PANC0327	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.5700022144222122	[284]	[196,157,214,115]	-7	hSpCas9	negative selection	7734092
52950825	52950848	12	+	27260156	PANC0327	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.5564384212697981	[143]	[158,141,217,236]	7	hSpCas9	negative selection	7734093
52951835	52951858	12	+	27260156	PANC0327	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.4972903358180226	[348]	[190,195,169,321]	-6	hSpCas9	negative selection	7798346
52952109	52952132	12	+	27260156	PANC0327	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.16841862404883667	[266]	[222,331,219,278]	2	hSpCas9	negative selection	7798347
52952166	52952189	12	-	27260156	PANC0327	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.6869870019694145	[476]	[424,208,252,185]	-7	hSpCas9	negative selection	7798348
52951843	52951866	12	-	27260156	NCIH2009	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.0821120582482946	[216]	[360,257,254]	-1	hSpCas9	negative selection	7855342
52950744	52950767	12	+	27260156	NCIH2009	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.2814640752141865	[284]	[538,220,265]	-4	hSpCas9	negative selection	7855343
52950825	52950848	12	+	27260156	NCIH2009	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.19531441722512	[143]	[246,338,105]	2	hSpCas9	negative selection	7855344
52951835	52951858	12	+	27260156	NCIH2009	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.004299943247330573	[348]	[537,369,561]	0	hSpCas9	negative selection	7919597
52952109	52952132	12	+	27260156	NCIH2009	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.07495060931983544	[266]	[500,364,333]	1	hSpCas9	negative selection	7919598
52952166	52952189	12	-	27260156	NCIH2009	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-1.0723284375427784	[476]	[342,393,216]	-8	hSpCas9	negative selection	7919599
52951843	52951866	12	-	27260156	NCIH1373	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.029771021395782915	[216]	[491,298,64,32]	0	hSpCas9	negative selection	7976593
52950744	52950767	12	+	27260156	NCIH1373	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.9212101410094707	[284]	[132,140,161,62]	-7	hSpCas9	negative selection	7976594
52950825	52950848	12	+	27260156	NCIH1373	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-1.1859138347612663	[143]	[80,52,48,27]	-8	hSpCas9	negative selection	7976595
52951835	52951858	12	+	27260156	NCIH1373	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.2277746619603156	[348]	[399,357,264,83]	-2	hSpCas9	negative selection	8040848
52952109	52952132	12	+	27260156	NCIH1373	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	-0.22494547008187293	[266]	[468,85,197,85]	-2	hSpCas9	negative selection	8040849
52952166	52952189	12	-	27260156	NCIH1373	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.9269478828664577	[476]	[284,146,407,77]	-7	hSpCas9	negative selection	8040850
52951843	52951866	12	-	27260156	PATU8902	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.5750909321667881	[216]	[946,222,173,526]	6	hSpCas9	negative selection	8097844
52950744	52950767	12	+	27260156	PATU8902	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.27183625013777896	[284]	[799,347,456,285]	2	hSpCas9	negative selection	8097845
52950825	52950848	12	+	27260156	PATU8902	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.662666659331314	[143]	[128,29,91,281]	-6	hSpCas9	negative selection	8097846
52951835	52951858	12	+	27260156	PATU8902	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.05702125965429922	[348]	[384,531,490,630]	0	hSpCas9	negative selection	8162099
52952109	52952132	12	+	27260156	PATU8902	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	1.1709741700414993	[266]	[565,1564,310,1070]	9	hSpCas9	negative selection	8162100
52952166	52952189	12	-	27260156	PATU8902	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.8122853543113807	[476]	[470,475,326,230]	-6	hSpCas9	negative selection	8162101
52951843	52951866	12	-	27260156	PANC1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.820157719171944	[216]	[398,436,296,216]	9	hSpCas9	negative selection	8219095
52950744	52950767	12	+	27260156	PANC1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.0557811331746092	[284]	[406,271,182,165]	0	hSpCas9	negative selection	8219096
52950825	52950848	12	+	27260156	PANC1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.09662791519351188	[143]	[56,188,106,178]	1	hSpCas9	negative selection	8219097
52951835	52951858	12	+	27260156	PANC1	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.17985972231882755	[348]	[255,307,327,438]	3	hSpCas9	negative selection	8283350
52952109	52952132	12	+	27260156	PANC1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.4458921769914875	[266]	[266,496,236,285]	7	hSpCas9	negative selection	8283351
52952166	52952189	12	-	27260156	PANC1	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.10170853828947525	[476]	[250,308,493,444]	-2	hSpCas9	negative selection	8283352
52951843	52951866	12	-	27260156	PANC0813	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.09954918172774807	[216]	[297,255,176,357]	1	hSpCas9	negative selection	8340346
52950744	52950767	12	+	27260156	PANC0813	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.5557668624732127	[284]	[268,215,247,183]	-7	hSpCas9	negative selection	8340347
52950825	52950848	12	+	27260156	PANC0813	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.08720486175388364	[143]	[148,139,264,162]	1	hSpCas9	negative selection	8340348
52951835	52951858	12	+	27260156	PANC0813	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.30645949988133736	[348]	[416,362,327,230]	-5	hSpCas9	negative selection	8404601
52952109	52952132	12	+	27260156	PANC0813	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	-0.07692793269737053	[266]	[253,249,326,350]	-1	hSpCas9	negative selection	8404602
52952166	52952189	12	-	27260156	PANC0813	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.9354518475367902	[476]	[336,266,339,234]	-8	hSpCas9	negative selection	8404603
52951843	52951866	12	-	27260156	RDES	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.13149066170385626	[216]	[151,243,249,282]	-2	hSpCas9	negative selection	8461597
52950744	52950767	12	+	27260156	RDES	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-1.0677500011733376	[284]	[95,93,286,170]	-9	hSpCas9	negative selection	8461598
52950825	52950848	12	+	27260156	RDES	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.48342662507078527	[143]	[114,128,105,118]	-7	hSpCas9	negative selection	8461599
52951835	52951858	12	+	27260156	RDES	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.008357945055744775	[348]	[393,386,344,466]	0	hSpCas9	negative selection	8525852
52952109	52952132	12	+	27260156	RDES	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.45781262407834367	[266]	[362,438,431,455]	7	hSpCas9	negative selection	8525853
52952166	52952189	12	-	27260156	RDES	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.7986879682568224	[476]	[351,305,250,333]	-8	hSpCas9	negative selection	8525854
52951843	52951866	12	-	27260156	PC3	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.41625259633544076	[216]	[226,272,489,233]	8	hSpCas9	negative selection	8582848
52950744	52950767	12	+	27260156	PC3	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.13230219342281924	[284]	[107,235,542,312]	-3	hSpCas9	negative selection	8582849
52950825	52950848	12	+	27260156	PC3	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.36700731240739715	[143]	[117,80,103,120]	-7	hSpCas9	negative selection	8582850
52951835	52951858	12	+	27260156	PC3	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.1739359973370827	[348]	[306,452,451,365]	4	hSpCas9	negative selection	8647103
52952109	52952132	12	+	27260156	PC3	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.4108379041337236	[266]	[185,435,402,451]	8	hSpCas9	negative selection	8647104
52952166	52952189	12	-	27260156	PC3	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.3334581274846067	[476]	[192,248,986,376]	-6	hSpCas9	negative selection	8647105
52951843	52951866	12	-	27260156	PATU8988T	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.5536267351243317	[216]	[199,318,205,525]	8	hSpCas9	negative selection	8704099
52950744	52950767	12	+	27260156	PATU8988T	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.23094240773612196	[284]	[232,149,219,335]	-4	hSpCas9	negative selection	8704100
52950825	52950848	12	+	27260156	PATU8988T	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.2804062211190834	[143]	[137,149,62,110]	-5	hSpCas9	negative selection	8704101
52951835	52951858	12	+	27260156	PATU8988T	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.014973620673425614	[348]	[360,415,272,289]	0	hSpCas9	negative selection	8768354
52952109	52952132	12	+	27260156	PATU8988T	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.7236506553912957	[266]	[462,252,595,368]	9	hSpCas9	negative selection	8768355
52952166	52952189	12	-	27260156	PATU8988T	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.1633024669915481	[476]	[641,378,242,378]	-3	hSpCas9	negative selection	8768356
52951843	52951866	12	-	27260156	T47D	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.0809310890582926	[216]	[236,260,224,230]	-2	hSpCas9	negative selection	8825350
52950744	52950767	12	+	27260156	T47D	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.1619192462166955	[284]	[287,282,274,343]	-4	hSpCas9	negative selection	8825351
52950825	52950848	12	+	27260156	T47D	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.12390222740783674	[143]	[154,158,155,144]	-3	hSpCas9	negative selection	8825352
52951835	52951858	12	+	27260156	T47D	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.07551084393363028	[348]	[396,468,518,319]	1	hSpCas9	negative selection	8889605
52952109	52952132	12	+	27260156	T47D	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.4502696202413055	[266]	[501,405,382,410]	8	hSpCas9	negative selection	8889606
52952166	52952189	12	-	27260156	T47D	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.5719851503090262	[476]	[397,381,361,351]	-8	hSpCas9	negative selection	8889607
52951843	52951866	12	-	27260156	SU8686	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.15137312809467085	[216]	[195,182,284,315]	2	hSpCas9	negative selection	8946601
52950744	52950767	12	+	27260156	SU8686	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.5456740580792966	[284]	[207,218,142,196]	-7	hSpCas9	negative selection	8946602
52950825	52950848	12	+	27260156	SU8686	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.060428439294003766	[143]	[112,134,172,185]	1	hSpCas9	negative selection	8946603
52951835	52951858	12	+	27260156	SU8686	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.41443636719192833	[348]	[288,193,292,267]	-6	hSpCas9	negative selection	9010856
52952109	52952132	12	+	27260156	SU8686	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	-0.21409202024481488	[266]	[178,289,236,197]	-4	hSpCas9	negative selection	9010857
52952166	52952189	12	-	27260156	SU8686	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.7237267698089233	[476]	[210,318,294,329]	-8	hSpCas9	negative selection	9010858
52951843	52951866	12	-	27260156	SKES1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.29288393055314377	[216]	[296,210,213,326]	6	hSpCas9	negative selection	9067852
52950744	52950767	12	+	27260156	SKES1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.3678944917039394	[284]	[379,232,158,140]	-7	hSpCas9	negative selection	9067853
52950825	52950848	12	+	27260156	SKES1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.17505196987421323	[143]	[133,226,155,136]	4	hSpCas9	negative selection	9067854
52951835	52951858	12	+	27260156	SKES1	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.4040954190792504	[348]	[531,479,397,442]	8	hSpCas9	negative selection	9132107
52952109	52952132	12	+	27260156	SKES1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.07895252103175765	[266]	[409,302,227,210]	1	hSpCas9	negative selection	9132108
52952166	52952189	12	-	27260156	SKES1	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.5923209007732929	[476]	[376,418,253,239]	-8	hSpCas9	negative selection	9132109
52951843	52951866	12	-	27260156	TOV112D	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.1897209081775617	[216]	[273,210,278,220]	3	hSpCas9	negative selection	9189103
52950744	52950767	12	+	27260156	TOV112D	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.2760045597151093	[284]	[170,392,218,193]	-5	hSpCas9	negative selection	9189104
52950825	52950848	12	+	27260156	TOV112D	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.5623787936736919	[143]	[215,244,305,95]	8	hSpCas9	negative selection	9189105
52951835	52951858	12	+	27260156	TOV112D	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.2725261567638885	[348]	[376,466,233,611]	5	hSpCas9	negative selection	9253358
52952109	52952132	12	+	27260156	TOV112D	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.33317680561514607	[266]	[267,387,405,292]	6	hSpCas9	negative selection	9253359
52952166	52952189	12	-	27260156	TOV112D	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.26258872986820664	[476]	[371,463,325,442]	-5	hSpCas9	negative selection	9253360
52951843	52951866	12	-	27260156	TC71	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.16921115282874466	[216]	[280,341,173,250]	4	hSpCas9	negative selection	9310354
52950744	52950767	12	+	27260156	TC71	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.06816763903494139	[284]	[258,382,315,201]	-2	hSpCas9	negative selection	9310355
52950825	52950848	12	+	27260156	TC71	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.09756867963413662	[143]	[119,156,157,141]	-3	hSpCas9	negative selection	9310356
52951835	52951858	12	+	27260156	TC71	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	-0.04249481247881842	[348]	[310,371,333,442]	-1	hSpCas9	negative selection	9374609
52952109	52952132	12	+	27260156	TC71	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.6512170188745748	[266]	[489,536,434,327]	9	hSpCas9	negative selection	9374610
52952166	52952189	12	-	27260156	TC71	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.3457356097612631	[476]	[277,429,458,445]	-7	hSpCas9	negative selection	9374611
52951843	52951866	12	-	27260156	TC32	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.3221644899549789	[216]	[272,154,361,269]	5	hSpCas9	negative selection	9431605
52950744	52950767	12	+	27260156	TC32	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.2422874403133084	[284]	[275,187,298,143]	-4	hSpCas9	negative selection	9431606
52950825	52950848	12	+	27260156	TC32	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.4086670879161296	[143]	[225,145,183,156]	7	hSpCas9	negative selection	9431607
52951835	52951858	12	+	27260156	TC32	viability	CCTGGACTCCATGAGAAATCTGG	KRT18	ENSG00000111057	0.18907316214263262	[348]	[333,206,519,515]	3	hSpCas9	negative selection	9495860
52952109	52952132	12	+	27260156	TC32	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.7306603183503935	[266]	[480,237,421,568]	9	hSpCas9	negative selection	9495861
52952166	52952189	12	-	27260156	TC32	viability	CGTTGAGCTGCTCCATCTGTAGG	KRT18	ENSG00000111057	-0.43659826775694655	[476]	[340,132,611,344]	-7	hSpCas9	negative selection	9495862
52950744	52950767	12	+	27869803	HPAFII	viability after 27 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.1561178545907299	[285]	[244,102,NaN]	1	hSpCas9	negative selection	9547312
52950744	52950767	12	+	27869803	HPAFII	viability after 15 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.5248343670222453	[285]	[241,195,NaN]	-5	hSpCas9	negative selection	9629761
52950744	52950767	12	+	27869803	ASPC1	viability after 36 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.6664650581369536	[697]	[234,64,164]	-6	hSpCas9	negative selection	9712210
52950744	52950767	12	+	27869803	PATU8988S	viability after 35 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.27063303382853293	[566]	[265,284,NaN]	3	hSpCas9	negative selection	9794659
52950744	52950767	12	+	27869803	PATU8988S	viability after 31 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.315561740958393	[566]	[305,249,NaN]	4	hSpCas9	negative selection	9877108
52950744	52950767	12	+	27869803	HPAFII	viability after 35 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.3781097400435218	[285]	[174,202,NaN]	2	hSpCas9	negative selection	9959557
52950744	52950767	12	+	27869803	HPAFII	viability after 31 days	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.2929338354348252	[285]	[210,180,NaN]	2	hSpCas9	negative selection	10042006
52949359	52949382	12	+	28162770	P31FUJ	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.2652671273405979	[210]	[297]	3	hSpCas9	negative selection	10181316
52950324	52950347	12	+	28162770	P31FUJ	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	0.0537205543417848	[131]	[160]	0	hSpCas9	negative selection	10181317
52950744	52950767	12	+	28162770	P31FUJ	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.7395855643777615	[210]	[413]	8	hSpCas9	negative selection	10181318
52949321	52949344	12	+	28162770	P31FUJ	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.13732189556015031	[189]	[202]	-1	hSpCas9	negative selection	10181319
52951843	52951866	12	-	28162770	P31FUJ	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	1.1606052788929226	[125]	[330]	9	hSpCas9	negative selection	10181320
52952109	52952132	12	+	28162770	P31FUJ	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.4413439974844588	[229]	[366]	5	hSpCas9	negative selection	10181321
52950825	52950848	12	+	28162770	P31FUJ	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.22020216763474498	[113]	[114]	-2	hSpCas9	negative selection	10181322
52952716	52952739	12	+	28162770	P31FUJ	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.2028223552612476	[660]	[893]	2	hSpCas9	negative selection	10181323
52952196	52952219	12	+	28162770	P31FUJ	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	0.07282407814388336	[88]	[109]	0	hSpCas9	negative selection	10181324
52949359	52949382	12	+	28162770	TF1	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	NaN	[NaN]	[180]	1	hSpCas9	negative selection	10350682
52950324	52950347	12	+	28162770	TF1	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10350683
52950744	52950767	12	+	28162770	TF1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	NaN	[NaN]	[290]	1	hSpCas9	negative selection	10350684
52949321	52949344	12	+	28162770	TF1	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	NaN	[NaN]	[146]	1	hSpCas9	negative selection	10350685
52951843	52951866	12	-	28162770	TF1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10350686
52952109	52952132	12	+	28162770	TF1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	NaN	[NaN]	[326]	1	hSpCas9	negative selection	10350687
52950825	52950848	12	+	28162770	TF1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10350688
52952716	52952739	12	+	28162770	TF1	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	NaN	[NaN]	[483]	1	hSpCas9	negative selection	10350689
52952196	52952219	12	+	28162770	TF1	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10350690
52949359	52949382	12	+	28162770	SKM1	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.7977262208598273	[40]	[125]	7	hSpCas9	negative selection	10520048
52950324	52950347	12	+	28162770	SKM1	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	0.3184795255278249	[43]	[96]	3	hSpCas9	negative selection	10520049
52950744	52950767	12	+	28162770	SKM1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.516800215429753	[50]	[128]	5	hSpCas9	negative selection	10520050
52949321	52949344	12	+	28162770	SKM1	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.28497367436455123	[50]	[73]	-2	hSpCas9	negative selection	10520051
52951843	52951866	12	-	28162770	SKM1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.2526360523518679	[61]	[91]	-2	hSpCas9	negative selection	10520052
52952109	52952132	12	+	28162770	SKM1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.017533629784748317	[75]	[135]	0	hSpCas9	negative selection	10520053
52950825	52950848	12	+	28162770	SKM1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.4068169924738754	[31]	[74]	4	hSpCas9	negative selection	10520054
52952716	52952739	12	+	28162770	SKM1	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.5250969726002626	[124]	[317]	5	hSpCas9	negative selection	10520055
52952196	52952219	12	+	28162770	SKM1	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-0.11150831521699045	[10]	[17]	-1	hSpCas9	negative selection	10520056
52949359	52949382	12	+	28162770	SKM1	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.7977262208598273	[40]	[125]	7	hSpCas9	negative selection	10689414
52950324	52950347	12	+	28162770	SKM1	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	0.3184795255278249	[43]	[96]	3	hSpCas9	negative selection	10689415
52950744	52950767	12	+	28162770	SKM1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.516800215429753	[50]	[128]	5	hSpCas9	negative selection	10689416
52949321	52949344	12	+	28162770	SKM1	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.28497367436455123	[50]	[73]	-2	hSpCas9	negative selection	10689417
52951843	52951866	12	-	28162770	SKM1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.2526360523518679	[61]	[91]	-2	hSpCas9	negative selection	10689418
52952109	52952132	12	+	28162770	SKM1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.017533629784748317	[75]	[135]	0	hSpCas9	negative selection	10689419
52950825	52950848	12	+	28162770	SKM1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.4068169924738754	[31]	[74]	4	hSpCas9	negative selection	10689420
52952716	52952739	12	+	28162770	SKM1	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.5250969726002626	[124]	[317]	5	hSpCas9	negative selection	10689421
52952196	52952219	12	+	28162770	SKM1	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-0.11150831521699045	[10]	[17]	-1	hSpCas9	negative selection	10689422
52949359	52949382	12	+	28162770	PL21	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	-0.4705527602577199	[155]	[48]	-3	hSpCas9	negative selection	10858780
52950324	52950347	12	+	28162770	PL21	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.481684425484425	[153]	[23]	-7	hSpCas9	negative selection	10858781
52950744	52950767	12	+	28162770	PL21	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.43529498774767705	[208]	[122]	4	hSpCas9	negative selection	10858782
52949321	52949344	12	+	28162770	PL21	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	0.052240919377006714	[194]	[87]	0	hSpCas9	negative selection	10858783
52951843	52951866	12	-	28162770	PL21	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.20013961448932005	[293]	[146]	1	hSpCas9	negative selection	10858784
52952109	52952132	12	+	28162770	PL21	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.8242111522495926	[278]	[214]	7	hSpCas9	negative selection	10858785
52950825	52950848	12	+	28162770	PL21	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.2958178801730913	[109]	[38]	-2	hSpCas9	negative selection	10858786
52952716	52952739	12	+	28162770	PL21	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.6793074511878798	[527]	[367]	6	hSpCas9	negative selection	10858787
52952196	52952219	12	+	28162770	PL21	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	0.35768089147580007	[51]	[28]	3	hSpCas9	negative selection	10858788
52949359	52949382	12	+	28162770	P31FUJ	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.2652671273405979	[210]	[297]	3	hSpCas9	negative selection	11028146
52950324	52950347	12	+	28162770	P31FUJ	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	0.0537205543417848	[131]	[160]	0	hSpCas9	negative selection	11028147
52950744	52950767	12	+	28162770	P31FUJ	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.7395855643777615	[210]	[413]	8	hSpCas9	negative selection	11028148
52949321	52949344	12	+	28162770	P31FUJ	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.13732189556015031	[189]	[202]	-1	hSpCas9	negative selection	11028149
52951843	52951866	12	-	28162770	P31FUJ	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	1.1606052788929226	[125]	[330]	9	hSpCas9	negative selection	11028150
52952109	52952132	12	+	28162770	P31FUJ	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.4413439974844588	[229]	[366]	5	hSpCas9	negative selection	11028151
52950825	52950848	12	+	28162770	P31FUJ	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.22020216763474498	[113]	[114]	-2	hSpCas9	negative selection	11028152
52952716	52952739	12	+	28162770	P31FUJ	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.2028223552612476	[660]	[893]	2	hSpCas9	negative selection	11028153
52952196	52952219	12	+	28162770	P31FUJ	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	0.07282407814388336	[88]	[109]	0	hSpCas9	negative selection	11028154
52949359	52949382	12	+	28162770	OCIAML5	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.23853597791690972	[107]	[229]	2	hSpCas9	negative selection	11197512
52950324	52950347	12	+	28162770	OCIAML5	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-0.010764316883055292	[95]	[171]	0	hSpCas9	negative selection	11197513
52950744	52950767	12	+	28162770	OCIAML5	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	1.1782361892995286	[105]	[432]	8	hSpCas9	negative selection	11197514
52949321	52949344	12	+	28162770	OCIAML5	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.24669785948100384	[116]	[177]	-2	hSpCas9	negative selection	11197515
52951843	52951866	12	-	28162770	OCIAML5	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.6862158309289416	[196]	[220]	-4	hSpCas9	negative selection	11197516
52952109	52952132	12	+	28162770	OCIAML5	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	1.0234348870181174	[126]	[465]	8	hSpCas9	negative selection	11197517
52950825	52950848	12	+	28162770	OCIAML5	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.8732172182545737	[61]	[204]	7	hSpCas9	negative selection	11197518
52952716	52952739	12	+	28162770	OCIAML5	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.4541574412759217	[350]	[867]	4	hSpCas9	negative selection	11197519
52952196	52952219	12	+	28162770	OCIAML5	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-1.044711648806393	[47]	[41]	-6	hSpCas9	negative selection	11197520
52949359	52949382	12	+	28162770	EOL1	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.02981981467059358	[250]	[134]	0	hSpCas9	negative selection	11366878
52950324	52950347	12	+	28162770	EOL1	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.5247596297930552	[141]	[25]	-7	hSpCas9	negative selection	11366879
52950744	52950767	12	+	28162770	EOL1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.18569754513497638	[366]	[169]	-1	hSpCas9	negative selection	11366880
52949321	52949344	12	+	28162770	EOL1	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.3147905418199027	[313]	[132]	-2	hSpCas9	negative selection	11366881
52951843	52951866	12	-	28162770	EOL1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.16856163282094688	[319]	[149]	-1	hSpCas9	negative selection	11366882
52952109	52952132	12	+	28162770	EOL1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	-0.8210696928485804	[445]	[132]	-5	hSpCas9	negative selection	11366883
52950825	52950848	12	+	28162770	EOL1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.550482053347997	[161]	[124]	5	hSpCas9	negative selection	11366884
52952716	52952739	12	+	28162770	EOL1	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.48378677730594555	[546]	[402]	4	hSpCas9	negative selection	11366885
52952196	52952219	12	+	28162770	EOL1	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	0.44455483045092103	[52]	[37]	4	hSpCas9	negative selection	11366886
52949359	52949382	12	+	28162770	MOLM13	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.55313666816309	[229]	[243]	4	hSpCas9	negative selection	11536244
52950324	52950347	12	+	28162770	MOLM13	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.121780121854105	[306]	[101]	-5	hSpCas9	negative selection	11536245
52950744	52950767	12	+	28162770	MOLM13	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	-0.4638046050645123	[329]	[172]	-3	hSpCas9	negative selection	11536246
52949321	52949344	12	+	28162770	MOLM13	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	0.7960315350307235	[277]	[348]	6	hSpCas9	negative selection	11536247
52951843	52951866	12	-	28162770	MOLM13	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.2139971147756422	[408]	[342]	1	hSpCas9	negative selection	11536248
52952109	52952132	12	+	28162770	MOLM13	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	1.293297681009834	[328]	[582]	8	hSpCas9	negative selection	11536249
52950825	52950848	12	+	28162770	MOLM13	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.16765635775653542	[164]	[133]	1	hSpCas9	negative selection	11536250
52952716	52952739	12	+	28162770	MOLM13	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.10389131526620066	[721]	[560]	0	hSpCas9	negative selection	11536251
52952196	52952219	12	+	28162770	MOLM13	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-1.3686118861725418	[74]	[20]	-6	hSpCas9	negative selection	11536252
52949359	52949382	12	+	28162770	HEL	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.814350210070556	[189]	[213]	7	hSpCas9	negative selection	11705610
52950324	52950347	12	+	28162770	HEL	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.9225948619718667	[218]	[36]	-7	hSpCas9	negative selection	11705611
52950744	52950767	12	+	28162770	HEL	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.8961871890049528	[301]	[359]	7	hSpCas9	negative selection	11705612
52949321	52949344	12	+	28162770	HEL	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	0.605649513265137	[196]	[191]	5	hSpCas9	negative selection	11705613
52951843	52951866	12	-	28162770	HEL	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-0.32046913663000715	[270]	[138]	-2	hSpCas9	negative selection	11705614
52952109	52952132	12	+	28162770	HEL	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.13254409968117306	[281]	[197]	1	hSpCas9	negative selection	11705615
52950825	52950848	12	+	28162770	HEL	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.31122468828379646	[150]	[119]	2	hSpCas9	negative selection	11705616
52952716	52952739	12	+	28162770	HEL	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.13728970139830166	[652]	[459]	1	hSpCas9	negative selection	11705617
52952196	52952219	12	+	28162770	HEL	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-1.0417593422717135	[134]	[41]	-6	hSpCas9	negative selection	11705618
52949359	52949382	12	+	28162770	MV411	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	1.9051563939392457	[115]	[365]	9	hSpCas9	negative selection	11874976
52950324	52950347	12	+	28162770	MV411	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-0.9909671885423035	[150]	[63]	-6	hSpCas9	negative selection	11874977
52950744	52950767	12	+	28162770	MV411	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.9844031449489813	[200]	[334]	8	hSpCas9	negative selection	11874978
52949321	52949344	12	+	28162770	MV411	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.769241190363855	[260]	[128]	-5	hSpCas9	negative selection	11874979
52951843	52951866	12	-	28162770	MV411	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.5772853089663759	[217]	[273]	5	hSpCas9	negative selection	11874980
52952109	52952132	12	+	28162770	MV411	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.5715013900141287	[269]	[337]	5	hSpCas9	negative selection	11874981
52950825	52950848	12	+	28162770	MV411	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.38145489875446303	[112]	[123]	3	hSpCas9	negative selection	11874982
52952716	52952739	12	+	28162770	MV411	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.4810097712492909	[403]	[474]	4	hSpCas9	negative selection	11874983
52952196	52952219	12	+	28162770	MV411	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	0.14790187723186077	[59]	[55]	1	hSpCas9	negative selection	11874984
52949359	52949382	12	+	28162770	MONOMAC1	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.35045094824293965	[90]	[132]	3	hSpCas9	negative selection	12044342
52950324	52950347	12	+	28162770	MONOMAC1	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.2294583247519313	[89]	[43]	-7	hSpCas9	negative selection	12044343
52950744	52950767	12	+	28162770	MONOMAC1	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.433440312913971	[103]	[160]	4	hSpCas9	negative selection	12044344
52949321	52949344	12	+	28162770	MONOMAC1	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	0.5501970825604796	[111]	[187]	5	hSpCas9	negative selection	12044345
52951843	52951866	12	-	28162770	MONOMAC1	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.6219998800456856	[122]	[216]	6	hSpCas9	negative selection	12044346
52952109	52952132	12	+	28162770	MONOMAC1	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.31658687194133994	[151]	[216]	3	hSpCas9	negative selection	12044347
52950825	52950848	12	+	28162770	MONOMAC1	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.38792565366160253	[69]	[104]	4	hSpCas9	negative selection	12044348
52952716	52952739	12	+	28162770	MONOMAC1	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.7358489570819093	[274]	[524]	7	hSpCas9	negative selection	12044349
52952196	52952219	12	+	28162770	MONOMAC1	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	1.4847871929141916	[23]	[76]	9	hSpCas9	negative selection	12044350
52949359	52949382	12	+	28162770	OCIAML2	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.9097939189553456	[28]	[301]	8	hSpCas9	negative selection	12213708
52950324	52950347	12	+	28162770	OCIAML2	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-0.6466601893336607	[36]	[130]	-5	hSpCas9	negative selection	12213709
52950744	52950767	12	+	28162770	OCIAML2	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.9723136706065671	[31]	[347]	8	hSpCas9	negative selection	12213710
52949321	52949344	12	+	28162770	OCIAML2	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	0.5899117166928896	[34]	[291]	6	hSpCas9	negative selection	12213711
52951843	52951866	12	-	28162770	OCIAML2	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	0.13771560291694585	[50]	[310]	1	hSpCas9	negative selection	12213712
52952109	52952132	12	+	28162770	OCIAML2	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	1.1318201022078362	[40]	[497]	9	hSpCas9	negative selection	12213713
52950825	52950848	12	+	28162770	OCIAML2	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	0.37874831171114925	[28]	[208]	3	hSpCas9	negative selection	12213714
52952716	52952739	12	+	28162770	OCIAML2	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	0.5355049609299405	[87]	[706]	5	hSpCas9	negative selection	12213715
52952196	52952219	12	+	28162770	OCIAML2	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-0.5530919854341341	[8]	[33]	-4	hSpCas9	negative selection	12213716
52949359	52949382	12	+	28162770	OCIAML3	viability	CCTGGCCACCGGGATAGCCGGGG	KRT18	ENSG00000111057	0.932538174171671	[41]	[241]	7	hSpCas9	negative selection	12383074
52950324	52950347	12	+	28162770	OCIAML3	viability	CCAGATCTTCGCAAATACTGTGG	KRT18	ENSG00000111057	-1.484383149149665	[37]	[40]	-7	hSpCas9	negative selection	12383075
52950744	52950767	12	+	28162770	OCIAML3	viability	CTATAGGTATGAGACAGAGCTGG	KRT18	ENSG00000111057	0.234720932526008	[66]	[237]	2	hSpCas9	negative selection	12383076
52949321	52949344	12	+	28162770	OCIAML3	viability	CGCTCCACCAGCTTCAGGGGCGG	KRT18	ENSG00000111057	-0.04319336201485266	[56]	[166]	0	hSpCas9	negative selection	12383077
52951843	52951866	12	-	28162770	OCIAML3	viability	GGCACTCACCAGATTTCTCATGG	KRT18	ENSG00000111057	-1.9509421850394386	[72]	[56]	-8	hSpCas9	negative selection	12383078
52952109	52952132	12	+	28162770	OCIAML3	viability	GCCCCTGCAGAAGGCCAGCTTGG	KRT18	ENSG00000111057	0.552213100526881	[74]	[331]	5	hSpCas9	negative selection	12383079
52950825	52950848	12	+	28162770	OCIAML3	viability	CAATATCACACGACTGCAGCTGG	KRT18	ENSG00000111057	-0.009045139603006902	[29]	[89]	0	hSpCas9	negative selection	12383080
52952716	52952739	12	+	28162770	OCIAML3	viability	TTACAGTCTTGGTGATGCCTTGG	KRT18	ENSG00000111057	-0.45314510448431355	[155]	[343]	-4	hSpCas9	negative selection	12383081
52952196	52952219	12	+	28162770	OCIAML3	viability	GCTGCACCTTGAGTCAGAGCTGG	KRT18	ENSG00000111057	-2.709484857744099	[25]	[11]	-9	hSpCas9	negative selection	12383082