Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:342574
• Symbol:KRT27
• Description:keratin 27

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT27

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
40782172	40782195	17	-	26472758	Jiyoye	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-0.36252699907233255	[207]	[121]	-3	hSpCas9	negative selection	86362
40780347	40780370	17	-	26472758	Jiyoye	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.4091126653217384	[80]	[45]	-3	hSpCas9	negative selection	86363
40779780	40779803	17	+	26472758	Jiyoye	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.39459850828843085	[128]	[73]	-3	hSpCas9	negative selection	86364
40782363	40782386	17	-	26472758	Jiyoye	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	0.8728389538546852	[20]	[28]	6	hSpCas9	negative selection	86365
40782312	40782335	17	-	26472758	Jiyoye	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	-0.5841074013930176	[164]	[82]	-4	hSpCas9	negative selection	86366
40782137	40782160	17	-	26472758	Jiyoye	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	0.6901093447773721	[119]	[145]	5	hSpCas9	negative selection	86367
40780419	40780442	17	-	26472758	Jiyoye	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.05003157201691005	[161]	[117]	0	hSpCas9	negative selection	86368
40779727	40779750	17	+	26472758	Jiyoye	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-1.182233024246475	[324]	[107]	-7	hSpCas9	negative selection	86369
40782302	40782325	17	-	26472758	Jiyoye	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.39157852645485497	[92]	[91]	3	hSpCas9	negative selection	86370
40782260	40782283	17	+	26472758	Jiyoye	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.46176086274144	[346]	[189]	-3	hSpCas9	negative selection	86371
40782172	40782195	17	-	26472758	KBM7	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-0.06248503175454978	[868,606]	[452,215]	0	hSpCas9	negative selection	277480
40780347	40780370	17	-	26472758	KBM7	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	0.36894650446213906	[529,441]	[221,357]	4	hSpCas9	negative selection	277481
40779780	40779803	17	+	26472758	KBM7	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	1.3026034769928185	[401,256]	[678,103]	9	hSpCas9	negative selection	277482
40782363	40782386	17	-	26472758	KBM7	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-0.14655774792144172	[213,166]	[121,42]	-1	hSpCas9	negative selection	277483
40782312	40782335	17	-	26472758	KBM7	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.4139768039653084	[414,303]	[302,150]	4	hSpCas9	negative selection	277484
40782137	40782160	17	-	26472758	KBM7	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.2516308768614144	[852,377]	[306,169]	-2	hSpCas9	negative selection	277485
40780419	40780442	17	-	26472758	KBM7	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	0.6782286661436303	[730,454]	[546,339]	7	hSpCas9	negative selection	277486
40779727	40779750	17	+	26472758	KBM7	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	0.07712583292628816	[894,957]	[323,587]	0	hSpCas9	negative selection	277487
40782302	40782325	17	-	26472758	KBM7	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	-0.03128269470836498	[523,273]	[157,196]	0	hSpCas9	negative selection	277488
40782260	40782283	17	+	26472758	KBM7	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.8203277783148941	[1566,1722]	[455,429]	-6	hSpCas9	negative selection	277489
40782172	40782195	17	-	26472758	Raji	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.323641170537946	[302]	[87]	3	hSpCas9	negative selection	468598
40780347	40780370	17	-	26472758	Raji	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.28372812465976377	[298]	[56]	-2	hSpCas9	negative selection	468599
40779780	40779803	17	+	26472758	Raji	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.787434227934344	[118]	[15]	-6	hSpCas9	negative selection	468600
40782363	40782386	17	-	26472758	Raji	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-1.1150088859628486	[83]	[8]	-7	hSpCas9	negative selection	468601
40782312	40782335	17	-	26472758	Raji	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	-0.030119988376335338	[197]	[44]	0	hSpCas9	negative selection	468602
40782137	40782160	17	-	26472758	Raji	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-1.1538817776071388	[325]	[33]	-7	hSpCas9	negative selection	468603
40780419	40780442	17	-	26472758	Raji	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	0.5630630191497893	[244]	[83]	5	hSpCas9	negative selection	468604
40779727	40779750	17	+	26472758	Raji	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.8296270486112546	[604]	[78]	-6	hSpCas9	negative selection	468605
40782302	40782325	17	-	26472758	Raji	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.2368347868288014	[244]	[66]	2	hSpCas9	negative selection	468606
40782260	40782283	17	+	26472758	Raji	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.07553044806628173	[780]	[171]	0	hSpCas9	negative selection	468607
40782172	40782195	17	-	26472758	K562	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-0.13366101561372723	[667]	[513]	-1	hSpCas9	negative selection	659716
40780347	40780370	17	-	26472758	K562	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	0.5877204733463763	[200]	[254]	5	hSpCas9	negative selection	659717
40779780	40779803	17	+	26472758	K562	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-1.018615678167347	[239]	[99]	-5	hSpCas9	negative selection	659718
40782363	40782386	17	-	26472758	K562	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-0.10481671321665076	[199]	[156]	0	hSpCas9	negative selection	659719
40782312	40782335	17	-	26472758	K562	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.20177439025795318	[308]	[299]	1	hSpCas9	negative selection	659720
40782137	40782160	17	-	26472758	K562	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	0.15874738675917882	[502]	[473]	1	hSpCas9	negative selection	659721
40780419	40780442	17	-	26472758	K562	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	0.9308848398250125	[406]	[654]	7	hSpCas9	negative selection	659722
40779727	40779750	17	+	26472758	K562	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.15792369876403	[1055]	[798]	-1	hSpCas9	negative selection	659723
40782302	40782325	17	-	26472758	K562	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.5929410325655224	[343]	[437]	5	hSpCas9	negative selection	659724
40782260	40782283	17	+	26472758	K562	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.5363308378089875	[1181]	[687]	-3	hSpCas9	negative selection	659725
40779493	40779516	17	+	26627737	DLD1	viability	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.5995717606016682	[899]	[351,472,451]	6	hSpCas9	negative selection	797600
40779590	40779613	17	-	26627737	DLD1	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.09838021572928457	[848]	[252,175,302]	-1	hSpCas9	negative selection	797601
40780359	40780382	17	-	26627737	DLD1	viability	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	0.06473038635378436	[325]	[114,118,88]	0	hSpCas9	negative selection	797602
40780422	40780445	17	-	26627737	DLD1	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.025916618191722973	[278]	[41,107,104]	0	hSpCas9	negative selection	797603
40782261	40782284	17	-	26627737	DLD1	viability	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.45820923184321644	[603]	[261,238,273]	5	hSpCas9	negative selection	797604
40782444	40782467	17	-	26627737	DLD1	viability	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.7468405476984697	[267]	[31,70,47]	-6	hSpCas9	negative selection	797605
40779493	40779516	17	+	26627737	GBM cells	viability after 5 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.5483355752415777	[444]	[322,374]	7	hSpCas9	negative selection	879915
40779590	40779613	17	-	26627737	GBM cells	viability after 5 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.45227437822101324	[399]	[379,206]	6	hSpCas9	negative selection	879916
40780359	40780382	17	-	26627737	GBM cells	viability after 5 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	0.08863160307655849	[184]	[114,95]	1	hSpCas9	negative selection	879917
40780422	40780445	17	-	26627737	GBM cells	viability after 5 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.5639296271728768	[110]	[82,92]	7	hSpCas9	negative selection	879918
40782261	40782284	17	-	26627737	GBM cells	viability after 5 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.5916922788133486	[304]	[248,243]	8	hSpCas9	negative selection	879919
40782444	40782467	17	-	26627737	GBM cells	viability after 5 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.3497652379710381	[119]	[61,38]	-5	hSpCas9	negative selection	879920
40779493	40779516	17	+	26627737	GBM cells	viability after 13 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.6897304578424668	[444]	[464,327]	8	hSpCas9	negative selection	962230
40779590	40779613	17	-	26627737	GBM cells	viability after 13 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.24828131829680566	[399]	[318,207]	3	hSpCas9	negative selection	962231
40780359	40780382	17	-	26627737	GBM cells	viability after 13 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	0.200080766304175	[184]	[111,117]	2	hSpCas9	negative selection	962232
40780422	40780445	17	-	26627737	GBM cells	viability after 13 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.27066575682604743	[110]	[70,73]	3	hSpCas9	negative selection	962233
40782261	40782284	17	-	26627737	GBM cells	viability after 13 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.5994589686767567	[304]	[274,230]	7	hSpCas9	negative selection	962234
40782444	40782467	17	-	26627737	GBM cells	viability after 13 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.5672858804911736	[119]	[65,25]	-6	hSpCas9	negative selection	962235
40779493	40779516	17	+	26627737	GBM cells	viability after 21 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	1.0432495090535137	[444]	[527,470]	9	hSpCas9	negative selection	1044545
40779590	40779613	17	-	26627737	GBM cells	viability after 21 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.08766585721731746	[399]	[227,182]	-1	hSpCas9	negative selection	1044546
40780359	40780382	17	-	26627737	GBM cells	viability after 21 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.23367066422349314	[184]	[85,84]	-2	hSpCas9	negative selection	1044547
40780422	40780445	17	-	26627737	GBM cells	viability after 21 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.4894097408528866	[110]	[43,41]	-4	hSpCas9	negative selection	1044548
40782261	40782284	17	-	26627737	GBM cells	viability after 21 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	1.032047174745677	[304]	[365,313]	8	hSpCas9	negative selection	1044549
40782444	40782467	17	-	26627737	GBM cells	viability after 21 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.3323961527808923	[119]	[56,46]	-3	hSpCas9	negative selection	1044550
40779493	40779516	17	+	26627737	RPE1	viability after 9 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.4570720704130753	[2046]	[932,810]	3	hSpCas9	negative selection	1126860
40779590	40779613	17	-	26627737	RPE1	viability after 9 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.22554052091912158	[1549]	[304,556]	-1	hSpCas9	negative selection	1126861
40780359	40780382	17	-	26627737	RPE1	viability after 9 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.13938324065190225	[679]	[270,92]	-1	hSpCas9	negative selection	1126862
40780422	40780445	17	-	26627737	RPE1	viability after 9 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	7.439710739351392	[2]	[221,86]	9	hSpCas9	negative selection	1126863
40782261	40782284	17	-	26627737	RPE1	viability after 9 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.2661551362457281	[1026]	[373,402]	2	hSpCas9	negative selection	1126864
40782444	40782467	17	-	26627737	RPE1	viability after 9 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-1.1231605730860124	[307]	[21,72]	-7	hSpCas9	negative selection	1126865
40779493	40779516	17	+	26627737	RPE1	viability after 12 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.4465731940978215	[2046]	[918,569]	3	hSpCas9	negative selection	1209175
40779590	40779613	17	-	26627737	RPE1	viability after 12 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.11740802519893012	[1549]	[260,513]	-1	hSpCas9	negative selection	1209176
40780359	40780382	17	-	26627737	RPE1	viability after 12 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	0.5726670843383952	[679]	[346,191]	4	hSpCas9	negative selection	1209177
40780422	40780445	17	-	26627737	RPE1	viability after 12 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	6.7813138755357345	[2]	[42,136]	9	hSpCas9	negative selection	1209178
40782261	40782284	17	-	26627737	RPE1	viability after 12 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.224471020171439	[1026]	[300,344]	1	hSpCas9	negative selection	1209179
40782444	40782467	17	-	26627737	RPE1	viability after 12 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-1.454198484584047	[307]	[2,58]	-7	hSpCas9	negative selection	1209180
40779493	40779516	17	+	26627737	RPE1	viability after 15 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.21413933975291521	[2046]	[856,492]	1	hSpCas9	negative selection	1291490
40779590	40779613	17	-	26627737	RPE1	viability after 15 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-1.3075736276770518	[1549]	[84,265]	-7	hSpCas9	negative selection	1291491
40780359	40780382	17	-	26627737	RPE1	viability after 15 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	0.20054108659209072	[679]	[302,141]	1	hSpCas9	negative selection	1291492
40780422	40780445	17	-	26627737	RPE1	viability after 15 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	7.171798049195822	[2]	[101,141]	9	hSpCas9	negative selection	1291493
40782261	40782284	17	-	26627737	RPE1	viability after 15 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.30262916057203565	[1026]	[480,239]	2	hSpCas9	negative selection	1291494
40782444	40782467	17	-	26627737	RPE1	viability after 15 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.5766829720034614	[307]	[62,53]	-4	hSpCas9	negative selection	1291495
40779493	40779516	17	+	26627737	RPE1	viability after 18 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.40010098077611067	[2046]	[873,573]	2	hSpCas9	negative selection	1373805
40779590	40779613	17	-	26627737	RPE1	viability after 18 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.49392699623070035	[1549]	[224,373]	-3	hSpCas9	negative selection	1373806
40780359	40780382	17	-	26627737	RPE1	viability after 18 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	0.6850338777825665	[679]	[470,106]	4	hSpCas9	negative selection	1373807
40780422	40780445	17	-	26627737	RPE1	viability after 18 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	7.368343644399381	[2]	[97,171]	9	hSpCas9	negative selection	1373808
40782261	40782284	17	-	26627737	RPE1	viability after 18 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	-0.2018614808395912	[1026]	[239,241]	-1	hSpCas9	negative selection	1373809
40782444	40782467	17	-	26627737	RPE1	viability after 18 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.9818735080638756	[307]	[29,54]	-6	hSpCas9	negative selection	1373810
40779493	40779516	17	+	26627737	HeLa	viability after 8 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.1369253209196154	[731]	[338,503,214]	1	hSpCas9	negative selection	1456120
40779590	40779613	17	-	26627737	HeLa	viability after 8 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.33778575548105294	[664]	[643,335,190]	3	hSpCas9	negative selection	1456121
40780359	40780382	17	-	26627737	HeLa	viability after 8 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-1.9707232348619548	[288]	[62,21,18]	-9	hSpCas9	negative selection	1456122
40780422	40780445	17	-	26627737	HeLa	viability after 8 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-1.4872470476412123	[553]	[167,95,16]	-9	hSpCas9	negative selection	1456123
40782261	40782284	17	-	26627737	HeLa	viability after 8 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.3430076247303219	[398]	[96,263,268]	3	hSpCas9	negative selection	1456124
40782444	40782467	17	-	26627737	HeLa	viability after 8 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.4793655256212863	[218]	[53,80,66]	-5	hSpCas9	negative selection	1456125
40779493	40779516	17	+	26627737	HeLa	viability after 12 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.6795384383107624	[731]	[728,414,323]	5	hSpCas9	negative selection	1538435
40779590	40779613	17	-	26627737	HeLa	viability after 12 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.4048191576524345	[664]	[198,249,168]	-4	hSpCas9	negative selection	1538436
40780359	40780382	17	-	26627737	HeLa	viability after 12 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-1.2725383952811447	[288]	[9,50,85]	-8	hSpCas9	negative selection	1538437
40780422	40780445	17	-	26627737	HeLa	viability after 12 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.7904678626426829	[553]	[56,140,195]	-6	hSpCas9	negative selection	1538438
40782261	40782284	17	-	26627737	HeLa	viability after 12 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.4514908521598007	[398]	[225,210,240]	4	hSpCas9	negative selection	1538439
40782444	40782467	17	-	26627737	HeLa	viability after 12 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	0.05485196310164686	[218]	[37,78,164]	0	hSpCas9	negative selection	1538440
40779493	40779516	17	+	26627737	HeLa	viability after 15 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	-0.11364759190500684	[731]	[168,378,279]	-1	hSpCas9	negative selection	1620750
40779590	40779613	17	-	26627737	HeLa	viability after 15 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.7577263868730294	[664]	[603,337,426]	6	hSpCas9	negative selection	1620751
40780359	40780382	17	-	26627737	HeLa	viability after 15 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.9416796706442574	[288]	[124,7,48]	-7	hSpCas9	negative selection	1620752
40780422	40780445	17	-	26627737	HeLa	viability after 15 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-1.6202568205268983	[553]	[90,89,35]	-8	hSpCas9	negative selection	1620753
40782261	40782284	17	-	26627737	HeLa	viability after 15 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.24382475895469116	[398]	[73,330,171]	2	hSpCas9	negative selection	1620754
40782444	40782467	17	-	26627737	HeLa	viability after 15 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.1051275083560046	[218]	[67,47,136]	-1	hSpCas9	negative selection	1620755
40779493	40779516	17	+	26627737	HeLa	viability after 18 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	-0.06923494356785176	[731]	[113,333,279]	0	hSpCas9	negative selection	1703065
40779590	40779613	17	-	26627737	HeLa	viability after 18 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.7850713291086305	[664]	[422,278,426]	6	hSpCas9	negative selection	1703066
40780359	40780382	17	-	26627737	HeLa	viability after 18 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.9880708555558306	[288]	[78,7,48]	-7	hSpCas9	negative selection	1703067
40780422	40780445	17	-	26627737	HeLa	viability after 18 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-1.5557613394889231	[553]	[67,73,35]	-8	hSpCas9	negative selection	1703068
40782261	40782284	17	-	26627737	HeLa	viability after 18 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.2701409456118678	[398]	[50,280,171]	2	hSpCas9	negative selection	1703069
40782444	40782467	17	-	26627737	HeLa	viability after 18 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.10890831382265731	[218]	[44,39,136]	-1	hSpCas9	negative selection	1703070
40779493	40779516	17	+	26627737	HCT116	viability after 6 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.18822436503361173	[1185]	[156,242]	1	hSpCas9	negative selection	1785380
40779590	40779613	17	-	26627737	HCT116	viability after 6 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	2.205766600476749	[692]	[606,444]	9	hSpCas9	negative selection	1785381
40780359	40780382	17	-	26627737	HCT116	viability after 6 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	0.5818640126201291	[153]	[81,10]	3	hSpCas9	negative selection	1785382
40780422	40780445	17	-	26627737	HCT116	viability after 6 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.6974427835806098	[412]	[79,17]	-4	hSpCas9	negative selection	1785383
40782261	40782284	17	-	26627737	HCT116	viability after 6 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	1.618913136016007	[701]	[162,435]	8	hSpCas9	negative selection	1785384
40782444	40782467	17	-	26627737	HCT116	viability after 6 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-1.7072671760881684	[353]	[27,10]	-7	hSpCas9	negative selection	1785385
40779493	40779516	17	+	26627737	HCT116	viability after 8 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.07057947691420563	[687]	[448,409,336]	0	hSpCas9	negative selection	1867695
40779590	40779613	17	-	26627737	HCT116	viability after 8 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.3445826760419331	[513]	[281,147,239]	-4	hSpCas9	negative selection	1867696
40780359	40780382	17	-	26627737	HCT116	viability after 8 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	1.8930306375243353	[51]	[165,102,51]	9	hSpCas9	negative selection	1867697
40780422	40780445	17	-	26627737	HCT116	viability after 8 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	1.3957136449075698	[140]	[108,249,251]	9	hSpCas9	negative selection	1867698
40782261	40782284	17	-	26627737	HCT116	viability after 8 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	-0.023930513898480277	[383]	[154,227,239]	0	hSpCas9	negative selection	1867699
40782444	40782467	17	-	26627737	HCT116	viability after 8 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-1.197941219177793	[122]	[42,26,18]	-9	hSpCas9	negative selection	1867700
40779493	40779516	17	+	26627737	HCT116	viability after 9 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.5044545119027801	[1185]	[465,435]	4	hSpCas9	negative selection	1950010
40779590	40779613	17	-	26627737	HCT116	viability after 9 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.5098141019908612	[692]	[339,202]	4	hSpCas9	negative selection	1950011
40780359	40780382	17	-	26627737	HCT116	viability after 9 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.5236717191446483	[153]	[60,2]	-4	hSpCas9	negative selection	1950012
40780422	40780445	17	-	26627737	HCT116	viability after 9 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	1.7420108755240196	[412]	[121,563]	9	hSpCas9	negative selection	1950013
40782261	40782284	17	-	26627737	HCT116	viability after 9 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	1.096861697388831	[701]	[682,177]	7	hSpCas9	negative selection	1950014
40782444	40782467	17	-	26627737	HCT116	viability after 9 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	0.6676752222483033	[353]	[286,41]	5	hSpCas9	negative selection	1950015
40779493	40779516	17	+	26627737	HCT116	viability after 12 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	-0.004814846213585522	[687]	[332,381,368]	0	hSpCas9	negative selection	2032325
40779590	40779613	17	-	26627737	HCT116	viability after 12 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.8335005125943884	[513]	[161,75,213]	-7	hSpCas9	negative selection	2032326
40780359	40780382	17	-	26627737	HCT116	viability after 12 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	1.967754176928668	[51]	[90,144,86]	9	hSpCas9	negative selection	2032327
40780422	40780445	17	-	26627737	HCT116	viability after 12 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.8345595369753396	[140]	[86,115,196]	7	hSpCas9	negative selection	2032328
40782261	40782284	17	-	26627737	HCT116	viability after 12 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.3132942000832237	[383]	[121,227,412]	3	hSpCas9	negative selection	2032329
40782444	40782467	17	-	26627737	HCT116	viability after 12 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	0.06687434247798252	[122]	[42,96,65]	0	hSpCas9	negative selection	2032330
40779493	40779516	17	+	26627737	HCT116	viability after 15 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	-0.16679173619484455	[687]	[421,335,306]	-2	hSpCas9	negative selection	2114640
40779590	40779613	17	-	26627737	HCT116	viability after 15 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.5263073954248487	[513]	[294,222,108]	-5	hSpCas9	negative selection	2114641
40780359	40780382	17	-	26627737	HCT116	viability after 15 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	1.4135161430743377	[51]	[113,61,66]	9	hSpCas9	negative selection	2114642
40780422	40780445	17	-	26627737	HCT116	viability after 15 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	1.220050472544565	[140]	[86,232,232]	8	hSpCas9	negative selection	2114643
40782261	40782284	17	-	26627737	HCT116	viability after 15 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.1697186204595918	[383]	[161,264,305]	1	hSpCas9	negative selection	2114644
40782444	40782467	17	-	26627737	HCT116	viability after 15 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	0.3806972694884546	[122]	[74,119,78]	3	hSpCas9	negative selection	2114645
40779493	40779516	17	+	26627737	HCT116	viability after 18 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	-0.09507936974831832	[687]	[254,361,313]	-1	hSpCas9	negative selection	2196955
40779590	40779613	17	-	26627737	HCT116	viability after 18 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.31576889939553743	[513]	[304,172,118]	-3	hSpCas9	negative selection	2196956
40780359	40780382	17	-	26627737	HCT116	viability after 18 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	2.195803237506331	[51]	[174,77,93]	9	hSpCas9	negative selection	2196957
40780422	40780445	17	-	26627737	HCT116	viability after 18 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.6708067155985435	[140]	[79,124,119]	5	hSpCas9	negative selection	2196958
40782261	40782284	17	-	26627737	HCT116	viability after 18 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.4293431634614879	[383]	[69,357,317]	3	hSpCas9	negative selection	2196959
40782444	40782467	17	-	26627737	HCT116	viability after 18 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	0.0711672656293334	[122]	[90,79,12]	0	hSpCas9	negative selection	2196960
40780333	40780356	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCACTGAGAGTTTCCAGCTGG	KRT27	ENSG00000171446	-0.03927432734232615	[3,3]	[3,2]	0	hSpCas9	positive selection	2998169
40782450	40782473	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGAGCCAAGTCTCCTGGAGG	KRT27	ENSG00000171446	0.06620747601969804	[3,3]	[2,3]	1	hSpCas9	positive selection	2998170
40782194	40782217	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCCAGGTAGGAGGCCAAGCGG	KRT27	ENSG00000171446	-0.42755489780985156	[0,0]	[0,0]	-6	hSpCas9	positive selection	2998171
40782089	40782112	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGTAATCATGATCAAGGCCACGG	KRT27	ENSG00000171446	0.0996716700750637	[3,3]	[4,2]	2	hSpCas9	positive selection	2998172
40780333	40780356	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCACTGAGAGTTTCCAGCTGG	KRT27	ENSG00000171446	-0.056818429516390836	[3,3]	[5,0]	-1	hSpCas9	positive selection	3066027
40782450	40782473	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGAGCCAAGTCTCCTGGAGG	KRT27	ENSG00000171446	-0.42333733898992854	[3,3]	[4,0]	-6	hSpCas9	positive selection	3066028
40782194	40782217	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCCAGGTAGGAGGCCAAGCGG	KRT27	ENSG00000171446	-0.04909672171899926	[0,0]	[0,0]	0	hSpCas9	positive selection	3066029
40782089	40782112	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGTAATCATGATCAAGGCCACGG	KRT27	ENSG00000171446	0.7269638393472884	[3,3]	[3,4]	9	hSpCas9	positive selection	3066030
40780389	40780412		-	24336571	A375	resistance to PLX after 7 days	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.32268945741561583	[4,3]	[5,5]	8	hSpCas9	positive selection	3123756
40780422	40780445		-	24336571	A375	resistance to PLX after 7 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.1540725528095039	[10,11]	[8,10]	-5	hSpCas9	positive selection	3123757
40781213	40781236		+	24336571	A375	resistance to PLX after 7 days	GTCTTGCATTATCATTTTGCAGG	KRT27	ENSG00000171446	-0.3669695450093872	[14,12]	[8,11]	-9	hSpCas9	positive selection	3123758
40780389	40780412		-	24336571	A375	resistance to PLX after 14 days	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.026319129557749843	[4,6]	[2,1]	0	hSpCas9	positive selection	3181549
40780422	40780445		-	24336571	A375	resistance to PLX after 14 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.3884785987046314	[8,11]	[3,2]	-4	hSpCas9	positive selection	3181550
40781213	40781236		+	24336571	A375	resistance to PLX after 14 days	GTCTTGCATTATCATTTTGCAGG	KRT27	ENSG00000171446	-0.5190397836593708	[11,17]	[5,2]	-6	hSpCas9	positive selection	3181551
40780389	40780412		-	24336571	A375	viability after 7 days	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.06135286031976017	[4]	[4,3]	0	hSpCas9	negative selection	3239342
40780422	40780445		-	24336571	A375	viability after 7 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.11638331773374272	[12]	[10,11]	-2	hSpCas9	negative selection	3239343
40781213	40781236		+	24336571	A375	viability after 7 days	GTCTTGCATTATCATTTTGCAGG	KRT27	ENSG00000171446	-0.022161084273522036	[14]	[14,12]	0	hSpCas9	negative selection	3239344
40780389	40780412		-	24336571	A375	viability after 14 days	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.34913108940515913	[4]	[4,6]	4	hSpCas9	negative selection	3297135
40780422	40780445		-	24336571	A375	viability after 14 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.16938426598425346	[12]	[8,11]	-2	hSpCas9	negative selection	3297136
40781213	40781236		+	24336571	A375	viability after 14 days	GTCTTGCATTATCATTTTGCAGG	KRT27	ENSG00000171446	0.1130058774644137	[14]	[11,17]	1	hSpCas9	negative selection	3297137
40780389	40780412	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.02850752094995433	[149,149]	[0,0]	0	hSpCas9	positive selection	3376282
40779837	40779860	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	-1.1605263034400628	[341,341]	[0,0]	-7	hSpCas9	positive selection	3376283
40779768	40779791	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	0.6279695913662254	[98,98]	[0,0]	3	hSpCas9	positive selection	3376284
40780332	40780355	17	+	26780180	HT29	viability (Avana library 4 designs)	CCTCACTGAGAGTTTCCAGCTGG	KRT27	ENSG00000171446	1.00375848017108	[]	[]	4	hSpCas9	negative selection	3435621
40782449	40782472	17	+	26780180	HT29	viability (Avana library 4 designs)	GCAAGAGCCAAGTCTCCTGGAGG	KRT27	ENSG00000171446	1.10344599313566	[]	[]	4	hSpCas9	negative selection	3435622
40782193	40782216	17	+	26780180	HT29	viability (Avana library 4 designs)	TCTCCAGGTAGGAGGCCAAGCGG	KRT27	ENSG00000171446	0.533571884713724	[]	[]	2	hSpCas9	negative selection	3435623
40782088	40782111	17	+	26780180	HT29	viability (Avana library 4 designs)	TGTAATCATGATCAAGGCCACGG	KRT27	ENSG00000171446	0.369664773439343	[]	[]	1	hSpCas9	negative selection	3435624
40782449	40782472	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGAGCCAAGTCTCCTGGAGG	KRT27	ENSG00000171446	4.45236492149803	[]	[]	7	hSpCas9	negative selection	3523279
40782193	40782216	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCCAGGTAGGAGGCCAAGCGG	KRT27	ENSG00000171446	0.540331694487205	[]	[]	0	hSpCas9	negative selection	3523280
40782088	40782111	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTAATCATGATCAAGGCCACGG	KRT27	ENSG00000171446	-1.0792417203846	[]	[]	-1	hSpCas9	negative selection	3523281
40780332	40780355	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCACTGAGAGTTTCCAGCTGG	KRT27	ENSG00000171446	-1.50861942322534	[]	[]	-2	hSpCas9	negative selection	3523282
40782178	40782201	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTAGGGCTCGAACATTCTCCAGG	KRT27	ENSG00000171446	-1.73790886610392	[]	[]	-2	hSpCas9	negative selection	3523283
40780422	40780445	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	4.64890680622719	[]	[]	7	hSpCas9	negative selection	3523284
40782449	40782472	17	+	26780180	A375	viability (Avana lentiGuide)	GCAAGAGCCAAGTCTCCTGGAGG	KRT27	ENSG00000171446	0.800221057239332	[]	[]	1	hSpCas9	negative selection	3631938
40782193	40782216	17	+	26780180	A375	viability (Avana lentiGuide)	TCTCCAGGTAGGAGGCCAAGCGG	KRT27	ENSG00000171446	5.06466328299132	[]	[]	4	hSpCas9	negative selection	3631939
40782088	40782111	17	+	26780180	A375	viability (Avana lentiGuide)	TGTAATCATGATCAAGGCCACGG	KRT27	ENSG00000171446	-1.68182365529657	[]	[]	-3	hSpCas9	negative selection	3631940
40780332	40780355	17	+	26780180	A375	viability (Avana lentiGuide)	CCTCACTGAGAGTTTCCAGCTGG	KRT27	ENSG00000171446	0.905398536035999	[]	[]	1	hSpCas9	negative selection	3631941
40782178	40782201	17	+	26780180	A375	viability (Avana lentiGuide)	CTAGGGCTCGAACATTCTCCAGG	KRT27	ENSG00000171446	2.43733501262264	[]	[]	2	hSpCas9	negative selection	3631942
40780422	40780445	17	-	26780180	A375	viability (Avana lentiGuide)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	2.63410924209236	[]	[]	3	hSpCas9	negative selection	3631943
40782449	40782472	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGAGCCAAGTCTCCTGGAGG	KRT27	ENSG00000171446	-0.07742672413340593	[4]	[5,3]	-1	hSpCas9	positive selection	3740597
40782193	40782216	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCCAGGTAGGAGGCCAAGCGG	KRT27	ENSG00000171446	0.3551794928224261	[0]	[0,0]	9	hSpCas9	positive selection	3740598
40782088	40782111	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTAATCATGATCAAGGCCACGG	KRT27	ENSG00000171446	-0.23093043641168665	[6]	[5,4]	-4	hSpCas9	positive selection	3740599
40780332	40780355	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCACTGAGAGTTTCCAGCTGG	KRT27	ENSG00000171446	0.1334478111913409	[5]	[5,5]	3	hSpCas9	positive selection	3740600
40782178	40782201	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTAGGGCTCGAACATTCTCCAGG	KRT27	ENSG00000171446	0.07258654186625262	[4]	[5,4]	1	hSpCas9	positive selection	3740601
40780422	40780445	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.36237814843899885	[4]	[5,5]	9	hSpCas9	positive selection	3740602
40782449	40782472	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGAGCCAAGTCTCCTGGAGG	KRT27	ENSG00000171446	-0.14161087648168963	[5]	[2,5]	-2	hSpCas9	positive selection	3849204
40782193	40782216	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCCAGGTAGGAGGCCAAGCGG	KRT27	ENSG00000171446	-0.5909638011777112	[0]	[0,0]	-6	hSpCas9	positive selection	3849205
40782088	40782111	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTAATCATGATCAAGGCCACGG	KRT27	ENSG00000171446	-0.05398985477689677	[6]	[5,4]	-1	hSpCas9	positive selection	3849206
40780332	40780355	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCACTGAGAGTTTCCAGCTGG	KRT27	ENSG00000171446	0.2962732130013789	[5]	[6,5]	8	hSpCas9	positive selection	3849207
40782178	40782201	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTAGGGCTCGAACATTCTCCAGG	KRT27	ENSG00000171446	0.024750096213139672	[6]	[4,5]	0	hSpCas9	positive selection	3849208
40780422	40780445	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.32324469594583494	[4]	[2,2]	-4	hSpCas9	positive selection	3849209
40779837	40779860	17	-	26780180	A375	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.48971567822854	[]	[]	1	hSpCas9	negative selection	3955288
40780389	40780412	17	-	26780180	A375	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	1.32412714218165	[]	[]	7	hSpCas9	negative selection	3955289
40779590	40779613	17	-	26780180	A375	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	2.37921201236562	[]	[]	9	hSpCas9	negative selection	3955290
40780422	40780445	17	-	26780180	A375	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.768826505321558	[]	[]	3	hSpCas9	negative selection	3955291
40779768	40779791	17	+	26780180	A375	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	1.46505070946543	[]	[]	8	hSpCas9	negative selection	3955292
40779492	40779515	17	+	26780180	A375	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.563850835861531	[]	[]	1	hSpCas9	negative selection	3955293
40779837	40779860	17	-	26780180	HT29	viability (GeCKOv2 library)	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.213823549919288	[]	[]	0	hSpCas9	negative selection	4063254
40780389	40780412	17	-	26780180	HT29	viability (GeCKOv2 library)	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	1.51605994257279	[]	[]	7	hSpCas9	negative selection	4063255
40779590	40779613	17	-	26780180	HT29	viability (GeCKOv2 library)	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	2.40681641965656	[]	[]	9	hSpCas9	negative selection	4063256
40780422	40780445	17	-	26780180	HT29	viability (GeCKOv2 library)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.486774529407128	[]	[]	1	hSpCas9	negative selection	4063257
40779768	40779791	17	+	26780180	HT29	viability (GeCKOv2 library)	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	1.38135629673293	[]	[]	7	hSpCas9	negative selection	4063258
40779492	40779515	17	+	26780180	HT29	viability (GeCKOv2 library)	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.512714793815965	[]	[]	1	hSpCas9	negative selection	4063259
40780389	40780412	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.010380563269178245	[1]	[1,0]	0	hSpCas9	positive selection	4147721
40780422	40780445	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.2147353986180424	[4]	[2,1]	-5	hSpCas9	positive selection	4147722
40781213	40781236	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCTTGCATTATCATTTTGCAGG	KRT27	ENSG00000171446	0.07120421425501887	[3]	[2,1]	1	hSpCas9	positive selection	4147723
40780389	40780412	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.31906994347257817	[2]	[1,3,0,0]	2	hSpCas9	positive selection	4211743
40780422	40780445	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.41921280796080485	[2]	[3,1,0,0]	3	hSpCas9	positive selection	4211744
40781213	40781236	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCTTGCATTATCATTTTGCAGG	KRT27	ENSG00000171446	0.4672842921955097	[3]	[2,3,3,0]	3	hSpCas9	positive selection	4211745
40779590	40779613	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.7065294408461378	[3]	[1,1]	-9	hSpCas9	positive selection	4279140
40780422	40780445	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.03581304215845049	[1]	[0,1]	0	hSpCas9	positive selection	4279141
40779492	40779515	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.16018314733885025	[3]	[3,1]	3	hSpCas9	positive selection	4279142
40780389	40780412	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.16472238838679384	[2]	[2,1]	-3	hSpCas9	positive selection	4343395
40779837	40779860	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.31438129379003665	[3]	[3,3]	6	hSpCas9	positive selection	4343396
40779768	40779791	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.40066609807360754	[2]	[1,0]	-7	hSpCas9	positive selection	4343397
40779590	40779612	17	-	27760321	OCIAML3	viability	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-2.4493760804642624	[41,26]	[3,5]	-9	hSpCas9	negative selection	4413113
40780422	40780444	17	-	27760321	OCIAML3	viability	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.8999592763544717	[865,675]	[224,445]	-7	hSpCas9	negative selection	4413114
40782049	40782071	17	-	27760321	OCIAML3	viability	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-0.8091745757248057	[78,63]	[6,63]	-6	hSpCas9	negative selection	4413115
40782358	40782380	17	+	27760321	OCIAML3	viability	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.440384654534408	[711,550]	[545,820]	5	hSpCas9	negative selection	4413116
40782375	40782397	17	-	27760321	OCIAML3	viability	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.8299443549328748	[799,702]	[832,1315]	8	hSpCas9	negative selection	4413117
40779590	40779612	17	-	27760321	OCIAML2	viability	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.20854263019443353	[41,26]	[42,16]	2	hSpCas9	negative selection	4496576
40780422	40780444	17	-	27760321	OCIAML2	viability	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.20691353959148784	[865,675]	[436,667]	-3	hSpCas9	negative selection	4496577
40782049	40782071	17	-	27760321	OCIAML2	viability	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	0.061077714792411086	[78,63]	[56,63]	0	hSpCas9	negative selection	4496578
40782358	40782380	17	+	27760321	OCIAML2	viability	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.46060901563528567	[711,550]	[599,826]	6	hSpCas9	negative selection	4496579
40782375	40782397	17	-	27760321	OCIAML2	viability	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.4489311952555711	[799,702]	[718,971]	6	hSpCas9	negative selection	4496580
40779590	40779612	17	-	27760321	MV411	viability	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.9190864275794004	[41,26]	[69,0]	6	hSpCas9	negative selection	4580039
40780422	40780444	17	-	27760321	MV411	viability	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.6475142959862216	[865,675]	[488,1245]	5	hSpCas9	negative selection	4580040
40782049	40782071	17	-	27760321	MV411	viability	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-3.017425169252144	[78,63]	[0,12]	-9	hSpCas9	negative selection	4580041
40782358	40782380	17	+	27760321	MV411	viability	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	1.2688443880119467	[711,550]	[1203,685]	8	hSpCas9	negative selection	4580042
40782375	40782397	17	-	27760321	MV411	viability	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	1.2084940019129342	[799,702]	[1064,1261]	8	hSpCas9	negative selection	4580043
40779590	40779612	17	-	27760321	HL60	viability	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-1.08033207871692	[41,26]	[0,25]	-8	hSpCas9	negative selection	4663502
40780422	40780444	17	-	27760321	HL60	viability	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.840952854019492	[865,675]	[935,1315]	8	hSpCas9	negative selection	4663503
40782049	40782071	17	-	27760321	HL60	viability	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	0.6427859023425231	[78,63]	[80,100]	7	hSpCas9	negative selection	4663504
40782358	40782380	17	+	27760321	HL60	viability	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.3922240531501031	[711,550]	[577,771]	5	hSpCas9	negative selection	4663505
40782375	40782397	17	-	27760321	HL60	viability	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.7462536247423556	[799,702]	[817,1249]	8	hSpCas9	negative selection	4663506
40779590	40779612	17	-	27760321	HT1080	viability	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-3.256837660850384	[26,20]	[0,0]	-7	hSpCas9	negative selection	4746965
40780422	40780444	17	-	27760321	HT1080	viability	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.9853512843268792	[675,527]	[354,605]	5	hSpCas9	negative selection	4746966
40782049	40782071	17	-	27760321	HT1080	viability	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-4.505162899635366	[63,49]	[0,0]	-8	hSpCas9	negative selection	4746967
40782358	40782380	17	+	27760321	HT1080	viability	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.5023135116716773	[550,429]	[92,477]	2	hSpCas9	negative selection	4746968
40782375	40782397	17	-	27760321	HT1080	viability	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.8332348646398917	[702,548]	[503,378]	4	hSpCas9	negative selection	4746969
40779590	40779612	17	-	27760321	HT29	viability after 7 days	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-1.1576754271167244	[26,20]	[1,30,6]	-8	hSpCas9	negative selection	4830428
40780422	40780444	17	-	27760321	HT29	viability after 7 days	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.4035381436206479	[675,527]	[401,850,478]	-5	hSpCas9	negative selection	4830429
40782049	40782071	17	-	27760321	HT29	viability after 7 days	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-0.1340154289909936	[63,49]	[46,132,18]	-2	hSpCas9	negative selection	4830430
40782358	40782380	17	+	27760321	HT29	viability after 7 days	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.587973644353605	[550,429]	[935,1187,723]	8	hSpCas9	negative selection	4830431
40782375	40782397	17	-	27760321	HT29	viability after 7 days	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.23190742832332645	[702,548]	[1001,1102,743]	3	hSpCas9	negative selection	4830432
40779590	40779612	17	-	27760321	HT29	viability after 25 days	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-1.0211854837472636	[26,20]	[0,37,0]	-6	hSpCas9	negative selection	4913891
40780422	40780444	17	-	27760321	HT29	viability after 25 days	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.047088417551130246	[675,527]	[886,436,657]	0	hSpCas9	negative selection	4913892
40782049	40782071	17	-	27760321	HT29	viability after 25 days	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-1.2977882590518286	[63,49]	[24,49,1]	-7	hSpCas9	negative selection	4913893
40782358	40782380	17	+	27760321	HT29	viability after 25 days	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.307519398231392	[550,429]	[726,648,702]	3	hSpCas9	negative selection	4913894
40782375	40782397	17	-	27760321	HT29	viability after 25 days	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.6423441957089395	[702,548]	[1282,859,1203]	7	hSpCas9	negative selection	4913895
40779590	40779612	17	-	27760321	HT29	viability after 22 days	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-1.5283617184128762	[26,20]	[0,26,0]	-7	hSpCas9	negative selection	4997354
40780422	40780444	17	-	27760321	HT29	viability after 22 days	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.028952364175588663	[675,527]	[834,669,620]	0	hSpCas9	negative selection	4997355
40782049	40782071	17	-	27760321	HT29	viability after 22 days	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-0.600603441696375	[63,49]	[46,68,13]	-5	hSpCas9	negative selection	4997356
40782358	40782380	17	+	27760321	HT29	viability after 22 days	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.4031326852351446	[550,429]	[694,802,752]	4	hSpCas9	negative selection	4997357
40782375	40782397	17	-	27760321	HT29	viability after 22 days	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.3267182382847733	[702,548]	[963,890,865]	3	hSpCas9	negative selection	4997358
40779590	40779612	17	-	27760321	HT29	viability after 19 days	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.3017769060321691	[26,20]	[0,8,85]	3	hSpCas9	negative selection	5080817
40780422	40780444	17	-	27760321	HT29	viability after 19 days	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.10146552414063625	[675,527]	[1021,443,503]	-1	hSpCas9	negative selection	5080818
40782049	40782071	17	-	27760321	HT29	viability after 19 days	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-0.8249941876344979	[63,49]	[77,34,2]	-6	hSpCas9	negative selection	5080819
40782358	40782380	17	+	27760321	HT29	viability after 19 days	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.40068505200883414	[550,429]	[883,847,512]	4	hSpCas9	negative selection	5080820
40782375	40782397	17	-	27760321	HT29	viability after 19 days	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	-0.08789530090154107	[702,548]	[956,334,754]	-1	hSpCas9	negative selection	5080821
40779590	40779612	17	-	27760321	HT29	viability after 16 days	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.007582947070055468	[26,20]	[49,31,0]	0	hSpCas9	negative selection	5164280
40780422	40780444	17	-	27760321	HT29	viability after 16 days	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.16904711352096446	[675,527]	[831,412,578]	-2	hSpCas9	negative selection	5164281
40782049	40782071	17	-	27760321	HT29	viability after 16 days	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-0.3369240476533073	[63,49]	[13,127,3]	-4	hSpCas9	negative selection	5164282
40782358	40782380	17	+	27760321	HT29	viability after 16 days	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.34485787795243	[550,429]	[736,678,678]	4	hSpCas9	negative selection	5164283
40782375	40782397	17	-	27760321	HT29	viability after 16 days	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.5305406049062373	[702,548]	[918,750,1362]	6	hSpCas9	negative selection	5164284
40779590	40779612	17	-	27760321	HT29	viability after 13 days	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-3.065570811651857	[26,20]	[0,5,2]	-9	hSpCas9	negative selection	5247743
40780422	40780444	17	-	27760321	HT29	viability after 13 days	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.12841479926962218	[675,527]	[640,590,681]	-1	hSpCas9	negative selection	5247744
40782049	40782071	17	-	27760321	HT29	viability after 13 days	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	0.22789518884860538	[63,49]	[40,123,67]	3	hSpCas9	negative selection	5247745
40782358	40782380	17	+	27760321	HT29	viability after 13 days	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.5958587188586753	[550,429]	[1141,777,670]	7	hSpCas9	negative selection	5247746
40782375	40782397	17	-	27760321	HT29	viability after 13 days	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.2957991882228006	[702,548]	[906,1022,752]	4	hSpCas9	negative selection	5247747
40779590	40779612	17	-	27760321	HT29	viability after 10 days	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-3.6809631866225034	[26,20]	[4,0,0]	-9	hSpCas9	negative selection	5331206
40780422	40780444	17	-	27760321	HT29	viability after 10 days	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.27441353543972247	[675,527]	[633,669,562]	-3	hSpCas9	negative selection	5331207
40782049	40782071	17	-	27760321	HT29	viability after 10 days	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	-0.4434543725488478	[63,49]	[23,104,29]	-5	hSpCas9	negative selection	5331208
40782358	40782380	17	+	27760321	HT29	viability after 10 days	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.6686309186229646	[550,429]	[900,1040,979]	8	hSpCas9	negative selection	5331209
40782375	40782397	17	-	27760321	HT29	viability after 10 days	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.5155639331023787	[702,548]	[1468,820,1054]	7	hSpCas9	negative selection	5331210
40779590	40779612	17	-	27760321	MOLM13	viability	AGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-4.2616276096965535	[41,26]	[0,0]	-9	hSpCas9	negative selection	5414669
40780422	40780444	17	-	27760321	MOLM13	viability	CTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.4508934251271929	[865,675]	[838,378]	3	hSpCas9	negative selection	5414670
40782049	40782071	17	-	27760321	MOLM13	viability	ATTGACGAACTTAAGAACCAGG	KRT27	ENSG00000171446	0.6500210731858331	[78,63]	[49,73]	4	hSpCas9	negative selection	5414671
40782358	40782380	17	+	27760321	MOLM13	viability	AGAAGCCACTTCCAATGCCTGG	KRT27	ENSG00000171446	0.4454798076513182	[711,550]	[552,420]	3	hSpCas9	negative selection	5414672
40782375	40782397	17	-	27760321	MOLM13	viability	GAAACACATGCGGTGTGCCAGG	KRT27	ENSG00000171446	0.40849682589703706	[799,702]	[653,482]	3	hSpCas9	negative selection	5414673
40782525	40782548	17	+	27661255	K562	viability	GGTGATGCTCTGATGGTGAACGG	KRT27	ENSG00000171446	0.07844235408433997	[1548,1496]	[1307,1265]	2	dCas9-KRAB	negative selection	5489273
40782512	40782535	17	-	27661255	K562	viability	GAGCATCACCGCAGAAACAAAGG	KRT27	ENSG00000171446	0.09850478250899508	[1480,1472]	[1292,1237]	3	dCas9-KRAB	negative selection	5489274
40779590	40779613	17	-	27260156	BXPC3	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.04085603227160095	[910]	[744,847,866,1307]	-1	hSpCas9	negative selection	5551600
40780422	40780445	17	-	27260156	BXPC3	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.3836517854320691	[144]	[168,147,244,239]	7	hSpCas9	negative selection	5551601
40779492	40779515	17	+	27260156	BXPC3	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5616904194914052	[548]	[767,911,769,948]	9	hSpCas9	negative selection	5551602
40780389	40780412	17	-	27260156	BXPC3	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.14471619209957076	[331]	[300,371,362,522]	3	hSpCas9	negative selection	5615855
40779837	40779860	17	-	27260156	BXPC3	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	-0.008272613668271811	[979]	[882,932,1135,1154]	0	hSpCas9	negative selection	5615856
40779768	40779791	17	+	27260156	BXPC3	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.1303774833473611	[327]	[336,259,284,376]	-3	hSpCas9	negative selection	5615857
40779590	40779613	17	-	27260156	A673	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.04550212789854802	[910]	[1210,1064,1230,1009]	1	hSpCas9	negative selection	5672851
40780422	40780445	17	-	27260156	A673	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.5009672272515386	[144]	[293,256,218,218]	9	hSpCas9	negative selection	5672852
40779492	40779515	17	+	27260156	A673	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5065158681922526	[548]	[1207,792,797,983]	9	hSpCas9	negative selection	5672853
40780389	40780412	17	-	27260156	A673	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.09304944440671487	[331]	[505,410,384,406]	2	hSpCas9	negative selection	5737106
40779837	40779860	17	-	27260156	A673	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.25402844098148814	[979]	[1587,1326,1379,1334]	6	hSpCas9	negative selection	5737107
40779768	40779791	17	+	27260156	A673	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.27013157974952806	[327]	[384,331,324,266]	-6	hSpCas9	negative selection	5737108
40779590	40779613	17	-	27260156	A375	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.07281060581067267	[910]	[1098,1489,976,974]	1	hSpCas9	negative selection	5794102
40780422	40780445	17	-	27260156	A375	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.003611707856103097	[144]	[151,204,181,146]	0	hSpCas9	negative selection	5794103
40779492	40779515	17	+	27260156	A375	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.7678408422990795	[548]	[948,1698,905,913]	9	hSpCas9	negative selection	5794104
40780389	40780412	17	-	27260156	A375	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.08162889203817297	[331]	[285,628,479,288]	1	hSpCas9	negative selection	5858357
40779837	40779860	17	-	27260156	A375	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.09893887640887455	[979]	[965,1678,1459,894]	1	hSpCas9	negative selection	5858358
40779768	40779791	17	+	27260156	A375	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.809144143447599	[327]	[218,207,131,302]	-8	hSpCas9	negative selection	5858359
40779590	40779613	17	-	27260156	COLO741	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.012990974754358287	[910]	[1312,1209,962]	0	hSpCas9	negative selection	5915353
40780422	40780445	17	-	27260156	COLO741	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.6650257548367735	[144]	[270,247,354]	9	hSpCas9	negative selection	5915354
40779492	40779515	17	+	27260156	COLO741	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5334451210187094	[548]	[1125,984,946]	9	hSpCas9	negative selection	5915355
40780389	40780412	17	-	27260156	COLO741	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.14174142308118243	[331]	[465,400,298]	-3	hSpCas9	negative selection	5979608
40779837	40779860	17	-	27260156	COLO741	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.049343588595572196	[979]	[1292,1489,1114]	1	hSpCas9	negative selection	5979609
40779768	40779791	17	+	27260156	COLO741	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.44785890839168874	[327]	[377,256,292]	-7	hSpCas9	negative selection	5979610
40779590	40779613	17	-	27260156	CAL120	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.23103998658322544	[910]	[778,1228,862]	-3	hSpCas9	negative selection	6036604
40780422	40780445	17	-	27260156	CAL120	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.34633948542901205	[144]	[268,248,176]	5	hSpCas9	negative selection	6036605
40779492	40779515	17	+	27260156	CAL120	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.3113230509896366	[548]	[850,773,916]	5	hSpCas9	negative selection	6036606
40780389	40780412	17	-	27260156	CAL120	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.04812527281481688	[331]	[449,255,575]	0	hSpCas9	negative selection	6100859
40779837	40779860	17	-	27260156	CAL120	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.11068520116053948	[979]	[957,1245,1684]	1	hSpCas9	negative selection	6100860
40779768	40779791	17	+	27260156	CAL120	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.45641496728299913	[327]	[276,359,252]	-6	hSpCas9	negative selection	6100861
40779590	40779613	17	-	27260156	CADOES1	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.05953739966978133	[910]	[1033,791,907,793]	1	hSpCas9	negative selection	6157855
40780422	40780445	17	-	27260156	CADOES1	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.34727638539668493	[144]	[166,184,169,163]	6	hSpCas9	negative selection	6157856
40779492	40779515	17	+	27260156	CADOES1	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.8341873071880483	[548]	[899,915,821,1006]	9	hSpCas9	negative selection	6157857
40780389	40780412	17	-	27260156	CADOES1	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.21281755563167282	[331]	[292,207,285,278]	-4	hSpCas9	negative selection	6222110
40779837	40779860	17	-	27260156	CADOES1	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.319216836475279	[979]	[1005,1059,1290,1193]	5	hSpCas9	negative selection	6222111
40779768	40779791	17	+	27260156	CADOES1	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.32651782679922325	[327]	[324,143,251,251]	-5	hSpCas9	negative selection	6222112
40779590	40779613	17	-	27260156	EWS502	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.05486900378654325	[910]	[903,990,950,861]	-1	hSpCas9	negative selection	6279106
40780422	40780445	17	-	27260156	EWS502	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.23543550238328614	[144]	[169,166,202,184]	4	hSpCas9	negative selection	6279107
40779492	40779515	17	+	27260156	EWS502	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.7637267846433669	[548]	[1050,885,923,1086]	9	hSpCas9	negative selection	6279108
40780389	40780412	17	-	27260156	EWS502	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.002090514227927942	[331]	[318,284,459,346]	0	hSpCas9	negative selection	6343361
40779837	40779860	17	-	27260156	EWS502	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.13136312075329282	[979]	[893,1220,1222,1239]	2	hSpCas9	negative selection	6343362
40779768	40779791	17	+	27260156	EWS502	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.18079723030050465	[327]	[294,312,310,306]	-3	hSpCas9	negative selection	6343363
40779590	40779613	17	-	27260156	EW8	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.12420667521251094	[910]	[889,753,765,821]	2	hSpCas9	negative selection	6400357
40780422	40780445	17	-	27260156	EW8	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.2541446194256689	[144]	[85,279,104,89]	4	hSpCas9	negative selection	6400358
40779492	40779515	17	+	27260156	EW8	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.7622139715754708	[548]	[1097,540,744,670]	9	hSpCas9	negative selection	6400359
40780389	40780412	17	-	27260156	EW8	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.2219687260103705	[331]	[316,294,256,394]	4	hSpCas9	negative selection	6464612
40779837	40779860	17	-	27260156	EW8	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.1194157858337428	[979]	[1094,996,602,823]	2	hSpCas9	negative selection	6464613
40779768	40779791	17	+	27260156	EW8	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	0.032728551621263424	[327]	[324,334,195,249]	0	hSpCas9	negative selection	6464614
40779590	40779613	17	-	27260156	CORL105	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.009146970674775323	[910]	[1117,906,1291,1014]	0	hSpCas9	negative selection	6521608
40780422	40780445	17	-	27260156	CORL105	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.8156918426827329	[144]	[352,219,477,175]	9	hSpCas9	negative selection	6521609
40779492	40779515	17	+	27260156	CORL105	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.4672034833764784	[548]	[909,652,1018,996]	8	hSpCas9	negative selection	6521610
40780389	40780412	17	-	27260156	CORL105	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.012112940483475776	[331]	[394,345,425,381]	0	hSpCas9	negative selection	6585863
40779837	40779860	17	-	27260156	CORL105	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.11245501796830681	[979]	[1257,1149,1341,1228]	2	hSpCas9	negative selection	6585864
40779768	40779791	17	+	27260156	CORL105	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.6755967229315027	[327]	[235,183,313,239]	-8	hSpCas9	negative selection	6585865
40779590	40779613	17	-	27260156	HS294T	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.47986468608099797	[910]	[336,673,449,514]	6	hSpCas9	negative selection	6642859
40780422	40780445	17	-	27260156	HS294T	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.8091851146046242	[144]	[51,95,126,126]	8	hSpCas9	negative selection	6642860
40779492	40779515	17	+	27260156	HS294T	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.470435981998171	[548]	[245,311,264,368]	6	hSpCas9	negative selection	6642861
40780389	40780412	17	-	27260156	HS294T	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.3908614184116574	[331]	[106,248,130,192]	5	hSpCas9	negative selection	6707114
40779837	40779860	17	-	27260156	HS294T	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	-0.05833140138616466	[979]	[327,336,313,502]	-1	hSpCas9	negative selection	6707115
40779768	40779791	17	+	27260156	HS294T	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.7480541358799411	[327]	[39,118,62,82]	-8	hSpCas9	negative selection	6707116
40779590	40779613	17	-	27260156	HCC44	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.14421962550179857	[910]	[1294,1037,992,1219]	2	hSpCas9	negative selection	6764110
40780422	40780445	17	-	27260156	HCC44	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.030125780260012558	[144]	[143,162,201,163]	0	hSpCas9	negative selection	6764111
40779492	40779515	17	+	27260156	HCC44	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5145994998869527	[548]	[1119,641,1036,825]	8	hSpCas9	negative selection	6764112
40780389	40780412	17	-	27260156	HCC44	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.04518544786228551	[331]	[483,322,340,318]	0	hSpCas9	negative selection	6828365
40779837	40779860	17	-	27260156	HCC44	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.04356799179023785	[979]	[1552,1023,1039,984]	0	hSpCas9	negative selection	6828366
40779768	40779791	17	+	27260156	HCC44	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.4508575907985748	[327]	[214,227,465,210]	-6	hSpCas9	negative selection	6828367
40779590	40779613	17	-	27260156	G402	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.10935715429926252	[910]	[1896,1046,1040,912]	1	hSpCas9	negative selection	6885361
40780422	40780445	17	-	27260156	G402	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.7886363731278503	[144]	[168,265,451,311]	8	hSpCas9	negative selection	6885362
40779492	40779515	17	+	27260156	G402	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	1.040547179766491	[548]	[1344,1434,1175,1540]	9	hSpCas9	negative selection	6885363
40780389	40780412	17	-	27260156	G402	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.47655617776463155	[331]	[949,414,441,495]	6	hSpCas9	negative selection	6949616
40779837	40779860	17	-	27260156	G402	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	-0.13273687147584856	[979]	[1171,1086,1273,848]	-2	hSpCas9	negative selection	6949617
40779768	40779791	17	+	27260156	G402	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.26220553217077636	[327]	[353,606,176,219]	-3	hSpCas9	negative selection	6949618
40779590	40779613	17	-	27260156	L33	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.16783168426171324	[910]	[1098,448,593,951]	3	hSpCas9	negative selection	7006612
40780422	40780445	17	-	27260156	L33	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.14583327420002057	[144]	[92,55,160,157]	3	hSpCas9	negative selection	7006613
40779492	40779515	17	+	27260156	L33	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.48937500670756456	[548]	[684,279,604,754]	8	hSpCas9	negative selection	7006614
40780389	40780412	17	-	27260156	L33	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.025548498562654287	[331]	[240,153,261,273]	0	hSpCas9	negative selection	7070867
40779837	40779860	17	-	27260156	L33	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	-0.03735502224137455	[979]	[990,363,658,891]	-1	hSpCas9	negative selection	7070868
40779768	40779791	17	+	27260156	L33	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.4067127334840911	[327]	[231,68,156,338]	-7	hSpCas9	negative selection	7070869
40779590	40779613	17	-	27260156	K562	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.19605081349819686	[910]	[627,536,1040,609]	-2	hSpCas9	negative selection	7127863
40780422	40780445	17	-	27260156	K562	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.9186972717833526	[144]	[110,32,111,22]	-8	hSpCas9	negative selection	7127864
40779492	40779515	17	+	27260156	K562	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.7480305737314397	[548]	[1301,438,699,844]	8	hSpCas9	negative selection	7127865
40780389	40780412	17	-	27260156	K562	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.24977085199114557	[331]	[322,117,437,124]	-3	hSpCas9	negative selection	7192118
40779837	40779860	17	-	27260156	K562	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	-0.01605635160862784	[979]	[647,799,1352,640]	0	hSpCas9	negative selection	7192119
40779768	40779791	17	+	27260156	K562	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.6676467088624414	[327]	[164,184,142,231]	-7	hSpCas9	negative selection	7192120
40779590	40779613	17	-	27260156	HT29	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.021177369924528677	[910]	[1051,970,1248,1073]	0	hSpCas9	negative selection	7249114
40780422	40780445	17	-	27260156	HT29	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.2053538058738369	[144]	[211,221,214,168]	4	hSpCas9	negative selection	7249115
40779492	40779515	17	+	27260156	HT29	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5410638305793571	[548]	[1015,1042,858,968]	9	hSpCas9	negative selection	7249116
40780389	40780412	17	-	27260156	HT29	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.2946854854860884	[331]	[382,202,346,368]	-5	hSpCas9	negative selection	7313369
40779837	40779860	17	-	27260156	HT29	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.1898689871477326	[979]	[1538,1549,1296,1101]	3	hSpCas9	negative selection	7313370
40779768	40779791	17	+	27260156	HT29	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	0.08593125320387768	[327]	[463,517,385,342]	1	hSpCas9	negative selection	7313371
40779590	40779613	17	-	27260156	MHHES1	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.3266570165867547	[910]	[1289,1448,1528,947]	6	hSpCas9	negative selection	7370365
40780422	40780445	17	-	27260156	MHHES1	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.5410116192053986	[144]	[290,180,232,239]	8	hSpCas9	negative selection	7370366
40779492	40779515	17	+	27260156	MHHES1	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.6630146553867782	[548]	[1218,835,887,966]	9	hSpCas9	negative selection	7370367
40780389	40780412	17	-	27260156	MHHES1	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.07448950728506443	[331]	[305,491,504,287]	1	hSpCas9	negative selection	7434620
40779837	40779860	17	-	27260156	MHHES1	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.16026182692634183	[979]	[1170,1497,1203,1085]	3	hSpCas9	negative selection	7434621
40779768	40779791	17	+	27260156	MHHES1	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.12279680494382039	[327]	[705,137,324,229]	-2	hSpCas9	negative selection	7434622
40779590	40779613	17	-	27260156	MEWO	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.020094718555980995	[910]	[840,723,956]	0	hSpCas9	negative selection	7491616
40780422	40780445	17	-	27260156	MEWO	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.3841409094822219	[144]	[150,185,188]	7	hSpCas9	negative selection	7491617
40779492	40779515	17	+	27260156	MEWO	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.18596864271331037	[548]	[644,685,432]	4	hSpCas9	negative selection	7491618
40780389	40780412	17	-	27260156	MEWO	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.19271249431191195	[331]	[320,226,276]	-4	hSpCas9	negative selection	7555871
40779837	40779860	17	-	27260156	MEWO	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.3204859833593192	[979]	[1125,1110,1193]	7	hSpCas9	negative selection	7555872
40779768	40779791	17	+	27260156	MEWO	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.06291889012648022	[327]	[365,341,186]	-1	hSpCas9	negative selection	7555873
40779590	40779613	17	-	27260156	LNCAPCLONEFGC	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.4802860362583973	[910]	[1137,1006,1151,1316]	7	hSpCas9	negative selection	7612867
40780422	40780445	17	-	27260156	LNCAPCLONEFGC	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.06222058820690135	[144]	[115,92,178,169]	0	hSpCas9	negative selection	7612868
40779492	40779515	17	+	27260156	LNCAPCLONEFGC	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.6045324640732752	[548]	[758,668,945,683]	8	hSpCas9	negative selection	7612869
40780389	40780412	17	-	27260156	LNCAPCLONEFGC	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.3182550844805272	[331]	[282,168,364,169]	-5	hSpCas9	negative selection	7677122
40779837	40779860	17	-	27260156	LNCAPCLONEFGC	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.29632469742834533	[979]	[1066,916,1212,1192]	4	hSpCas9	negative selection	7677123
40779768	40779791	17	+	27260156	LNCAPCLONEFGC	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.44656943929944637	[327]	[204,181,294,203]	-6	hSpCas9	negative selection	7677124
40779590	40779613	17	-	27260156	PANC0327	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.16708456118372428	[910]	[1212,401,761,1346]	2	hSpCas9	negative selection	7734118
40780422	40780445	17	-	27260156	PANC0327	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.45030029638622326	[144]	[192,84,181,256]	6	hSpCas9	negative selection	7734119
40779492	40779515	17	+	27260156	PANC0327	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.21752957061952977	[548]	[548,367,959,415]	3	hSpCas9	negative selection	7734120
40780389	40780412	17	-	27260156	PANC0327	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.39901180271277514	[331]	[275,112,182,340]	-5	hSpCas9	negative selection	7798373
40779837	40779860	17	-	27260156	PANC0327	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.1284197226471211	[979]	[1043,634,815,1358]	1	hSpCas9	negative selection	7798374
40779768	40779791	17	+	27260156	PANC0327	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.5216788663408964	[327]	[257,179,98,281]	-6	hSpCas9	negative selection	7798375
40779590	40779613	17	-	27260156	NCIH2009	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.28631061891832077	[910]	[2039,1299,1414]	4	hSpCas9	negative selection	7855369
40780422	40780445	17	-	27260156	NCIH2009	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.4784724219442391	[144]	[364,207,290]	6	hSpCas9	negative selection	7855370
40779492	40779515	17	+	27260156	NCIH2009	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.3697454729510154	[548]	[1217,797,1003]	5	hSpCas9	negative selection	7855371
40780389	40780412	17	-	27260156	NCIH2009	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.5761676186174401	[331]	[457,359,142]	-6	hSpCas9	negative selection	7919624
40779837	40779860	17	-	27260156	NCIH2009	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.22681595093339846	[979]	[1672,1558,1586]	3	hSpCas9	negative selection	7919625
40779768	40779791	17	+	27260156	NCIH2009	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.3495618645938271	[327]	[548,292,274]	-5	hSpCas9	negative selection	7919626
40779590	40779613	17	-	27260156	NCIH1373	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.3868871661194221	[910]	[1789,933,1663,271]	4	hSpCas9	negative selection	7976620
40780422	40780445	17	-	27260156	NCIH1373	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.2605829850893384	[144]	[121,73,148,53]	-3	hSpCas9	negative selection	7976621
40779492	40779515	17	+	27260156	NCIH1373	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	1.0002762054313503	[548]	[1778,1046,1168,266]	8	hSpCas9	negative selection	7976622
40780389	40780412	17	-	27260156	NCIH1373	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.9203022218071208	[331]	[1158,364,493,241]	8	hSpCas9	negative selection	8040875
40779837	40779860	17	-	27260156	NCIH1373	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.4795470567086264	[979]	[2325,756,1464,471]	5	hSpCas9	negative selection	8040876
40779768	40779791	17	+	27260156	NCIH1373	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	0.025584340858168908	[327]	[281,522,343,81]	0	hSpCas9	negative selection	8040877
40779590	40779613	17	-	27260156	PATU8902	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.13772130985160003	[910]	[1373,1865,1009,1427]	1	hSpCas9	negative selection	8097871
40780422	40780445	17	-	27260156	PATU8902	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.051527968460417295	[144]	[189,290,158,208]	0	hSpCas9	negative selection	8097872
40779492	40779515	17	+	27260156	PATU8902	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	1.014506030748847	[548]	[1629,1608,1481,1448]	9	hSpCas9	negative selection	8097873
40780389	40780412	17	-	27260156	PATU8902	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.18072268917080703	[331]	[605,362,94,674]	-2	hSpCas9	negative selection	8162126
40779837	40779860	17	-	27260156	PATU8902	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.3106601153045143	[979]	[1591,1906,1410,1953]	3	hSpCas9	negative selection	8162127
40779768	40779791	17	+	27260156	PATU8902	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-2.0554687557703417	[327]	[234,81,17,127]	-9	hSpCas9	negative selection	8162128
40779590	40779613	17	-	27260156	PANC1	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.14756745707853725	[910]	[825,734,656,613]	-2	hSpCas9	negative selection	8219122
40780422	40780445	17	-	27260156	PANC1	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.131400577850332	[144]	[183,175,87,106]	2	hSpCas9	negative selection	8219123
40779492	40779515	17	+	27260156	PANC1	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.4260725263487914	[548]	[480,971,664,500]	7	hSpCas9	negative selection	8219124
40780389	40780412	17	-	27260156	PANC1	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.6098909574550414	[331]	[134,214,277,132]	-7	hSpCas9	negative selection	8283377
40779837	40779860	17	-	27260156	PANC1	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.14917398111864522	[979]	[809,1212,865,894]	2	hSpCas9	negative selection	8283378
40779768	40779791	17	+	27260156	PANC1	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.34500802437456	[327]	[226,302,210,167]	-5	hSpCas9	negative selection	8283379
40779590	40779613	17	-	27260156	PANC0813	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.29503947382632856	[910]	[1337,1352,1204,1352]	5	hSpCas9	negative selection	8340373
40780422	40780445	17	-	27260156	PANC0813	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.0872049759354192	[144]	[256,108,122,237]	1	hSpCas9	negative selection	8340374
40779492	40779515	17	+	27260156	PANC0813	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.6564626492876477	[548]	[890,1147,852,1151]	9	hSpCas9	negative selection	8340375
40780389	40780412	17	-	27260156	PANC0813	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.6337322139519806	[331]	[286,216,247,255]	-7	hSpCas9	negative selection	8404628
40779837	40779860	17	-	27260156	PANC0813	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.06791624492826709	[979]	[1264,1018,1413,1136]	1	hSpCas9	negative selection	8404629
40779768	40779791	17	+	27260156	PANC0813	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.44704041354931623	[327]	[218,325,344,236]	-6	hSpCas9	negative selection	8404630
40779590	40779613	17	-	27260156	RDES	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.0003051510129981061	[910]	[854,953,1186,1250]	0	hSpCas9	negative selection	8461624
40780422	40780445	17	-	27260156	RDES	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.28636726157215153	[144]	[226,147,187,249]	4	hSpCas9	negative selection	8461625
40779492	40779515	17	+	27260156	RDES	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.7429595397824607	[548]	[853,949,1166,1322]	9	hSpCas9	negative selection	8461626
40780389	40780412	17	-	27260156	RDES	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.11302691643722579	[331]	[391,390,448,413]	1	hSpCas9	negative selection	8525879
40779837	40779860	17	-	27260156	RDES	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.36788244075728915	[979]	[1154,1369,1589,1787]	6	hSpCas9	negative selection	8525880
40779768	40779791	17	+	27260156	RDES	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.18378478728896952	[327]	[249,279,327,510]	-3	hSpCas9	negative selection	8525881
40779590	40779613	17	-	27260156	PC3	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.18965913173402738	[910]	[597,819,1587,1482]	4	hSpCas9	negative selection	8582875
40780422	40780445	17	-	27260156	PC3	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.15765534624187816	[144]	[113,189,202,154]	3	hSpCas9	negative selection	8582876
40779492	40779515	17	+	27260156	PC3	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5375640598733356	[548]	[527,981,1026,750]	9	hSpCas9	negative selection	8582877
40780389	40780412	17	-	27260156	PC3	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.19490675911651933	[331]	[168,203,490,407]	-4	hSpCas9	negative selection	8647130
40779837	40779860	17	-	27260156	PC3	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.1804841721519066	[979]	[772,952,1981,1097]	4	hSpCas9	negative selection	8647131
40779768	40779791	17	+	27260156	PC3	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.09094359341174696	[327]	[223,322,500,253]	-2	hSpCas9	negative selection	8647132
40779590	40779613	17	-	27260156	PATU8988T	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.006788285370913361	[910]	[703,935,777,1146]	0	hSpCas9	negative selection	8704126
40780422	40780445	17	-	27260156	PATU8988T	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.11229466894062257	[144]	[93,152,157,113]	-2	hSpCas9	negative selection	8704127
40779492	40779515	17	+	27260156	PATU8988T	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5114954436004988	[548]	[746,963,654,672]	8	hSpCas9	negative selection	8704128
40780389	40780412	17	-	27260156	PATU8988T	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.1665328078684083	[331]	[190,418,319,219]	-3	hSpCas9	negative selection	8768381
40779837	40779860	17	-	27260156	PATU8988T	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.12878315472571567	[979]	[891,1117,781,1388]	2	hSpCas9	negative selection	8768382
40779768	40779791	17	+	27260156	PATU8988T	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.13265201888209832	[327]	[195,269,290,406]	-2	hSpCas9	negative selection	8768383
40779590	40779613	17	-	27260156	T47D	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.007091083794280029	[910]	[1114,998,1042,1072]	0	hSpCas9	negative selection	8825377
40780422	40780445	17	-	27260156	T47D	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.2872336426211479	[144]	[256,206,183,175]	6	hSpCas9	negative selection	8825378
40779492	40779515	17	+	27260156	T47D	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.504116781561065	[548]	[887,794,974,980]	9	hSpCas9	negative selection	8825379
40780389	40780412	17	-	27260156	T47D	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.0597729386719098	[331]	[366,427,376,304]	-1	hSpCas9	negative selection	8889632
40779837	40779860	17	-	27260156	T47D	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.21282372792197957	[979]	[1411,1322,1173,1387]	4	hSpCas9	negative selection	8889633
40779768	40779791	17	+	27260156	T47D	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.4419563260374594	[327]	[277,223,264,365]	-7	hSpCas9	negative selection	8889634
40779590	40779613	17	-	27260156	SU8686	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.13130745205517436	[910]	[805,811,1012,1435]	2	hSpCas9	negative selection	8946628
40780422	40780445	17	-	27260156	SU8686	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.23922974569616295	[144]	[206,119,133,226]	4	hSpCas9	negative selection	8946629
40779492	40779515	17	+	27260156	SU8686	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.31778197987542073	[548]	[573,602,805,764]	5	hSpCas9	negative selection	8946630
40780389	40780412	17	-	27260156	SU8686	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.10084805771491073	[331]	[267,283,458,432]	1	hSpCas9	negative selection	9010883
40779837	40779860	17	-	27260156	SU8686	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.01886702965852627	[979]	[896,844,1042,1211]	0	hSpCas9	negative selection	9010884
40779768	40779791	17	+	27260156	SU8686	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.6318867691117376	[327]	[212,199,252,166]	-7	hSpCas9	negative selection	9010885
40779590	40779613	17	-	27260156	SKES1	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.03535073707851066	[910]	[1147,1003,959,672]	0	hSpCas9	negative selection	9067879
40780422	40780445	17	-	27260156	SKES1	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.842810279967335	[144]	[388,291,245,143]	9	hSpCas9	negative selection	9067880
40779492	40779515	17	+	27260156	SKES1	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5578981788445478	[548]	[937,901,916,521]	9	hSpCas9	negative selection	9067881
40780389	40780412	17	-	27260156	SKES1	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.1990499230253605	[331]	[366,192,320,270]	-4	hSpCas9	negative selection	9132134
40779837	40779860	17	-	27260156	SKES1	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.1737830510641023	[979]	[1346,1185,977,951]	4	hSpCas9	negative selection	9132135
40779768	40779791	17	+	27260156	SKES1	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.021935731316290674	[327]	[356,490,255,219]	0	hSpCas9	negative selection	9132136
40779590	40779613	17	-	27260156	TOV112D	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.03474526041753001	[910]	[876,1153,849,905]	0	hSpCas9	negative selection	9189130
40780422	40780445	17	-	27260156	TOV112D	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.813870637296159	[144]	[296,221,347,151]	9	hSpCas9	negative selection	9189131
40779492	40779515	17	+	27260156	TOV112D	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.26993146193746737	[548]	[712,1058,552,433]	5	hSpCas9	negative selection	9189132
40780389	40780412	17	-	27260156	TOV112D	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.09304960856206645	[331]	[257,318,364,301]	-2	hSpCas9	negative selection	9253385
40779837	40779860	17	-	27260156	TOV112D	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.09981954994056896	[979]	[1141,1115,1064,909]	2	hSpCas9	negative selection	9253386
40779768	40779791	17	+	27260156	TOV112D	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.20518961616901688	[327]	[327,281,346,187]	-4	hSpCas9	negative selection	9253387
40779590	40779613	17	-	27260156	TC71	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.13472540706408143	[910]	[846,935,884,890]	-4	hSpCas9	negative selection	9310381
40780422	40780445	17	-	27260156	TC71	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.3028774195928037	[144]	[162,149,233,220]	7	hSpCas9	negative selection	9310382
40779492	40779515	17	+	27260156	TC71	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.5152993249117466	[548]	[747,849,842,930]	9	hSpCas9	negative selection	9310383
40780389	40780412	17	-	27260156	TC71	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	-0.5424115563631581	[331]	[212,253,269,239]	-9	hSpCas9	negative selection	9374636
40779837	40779860	17	-	27260156	TC71	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.07576095017557405	[979]	[1023,1105,1076,1231]	2	hSpCas9	negative selection	9374637
40779768	40779791	17	+	27260156	TC71	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.0686801924808419	[327]	[333,310,331,365]	-2	hSpCas9	negative selection	9374638
40779590	40779613	17	-	27260156	TC32	viability	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.2672200991133751	[910]	[743,322,1155,809]	-5	hSpCas9	negative selection	9431632
40780422	40780445	17	-	27260156	TC32	viability	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.5231922773829003	[144]	[212,168,188,206]	8	hSpCas9	negative selection	9431633
40779492	40779515	17	+	27260156	TC32	viability	TTTCGCTTACCGTTGCTAAGAGG	KRT27	ENSG00000171446	0.7164012138122497	[548]	[851,671,1197,736]	9	hSpCas9	negative selection	9431634
40780389	40780412	17	-	27260156	TC32	viability	CAATGGTTTGCGAAGAGTCCTGG	KRT27	ENSG00000171446	0.07865260806557062	[331]	[384,121,560,344]	1	hSpCas9	negative selection	9495887
40779837	40779860	17	-	27260156	TC32	viability	AATGAAAGCTCTTCAGTGCGCGG	KRT27	ENSG00000171446	0.3176457270956041	[979]	[825,1039,1545,1266]	5	hSpCas9	negative selection	9495888
40779768	40779791	17	+	27260156	TC32	viability	TATTGTTCAGCAGAACCGTGAGG	KRT27	ENSG00000171446	-0.17742261411270166	[327]	[401,159,346,198]	-3	hSpCas9	negative selection	9495889
40779493	40779516	17	+	27869803	HPAFII	viability after 27 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.9426060549496522	[520]	[586,475,NaN]	7	hSpCas9	negative selection	9560618
40779590	40779613	17	-	27869803	HPAFII	viability after 27 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.07089530349530682	[343]	[277,83,NaN]	0	hSpCas9	negative selection	9560619
40780359	40780382	17	-	27869803	HPAFII	viability after 27 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.18270160063920726	[104]	[52,44,NaN]	-1	hSpCas9	negative selection	9560620
40780422	40780445	17	-	27869803	HPAFII	viability after 27 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.8647503769699593	[164]	[81,18,NaN]	-6	hSpCas9	negative selection	9560621
40782261	40782284	17	-	27869803	HPAFII	viability after 27 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.6671298704648018	[354]	[213,364,NaN]	5	hSpCas9	negative selection	9560622
40782444	40782467	17	-	27869803	HPAFII	viability after 27 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.03902688308145119	[131]	[12,112,NaN]	0	hSpCas9	negative selection	9560623
40779493	40779516	17	+	27869803	HPAFII	viability after 15 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.343942873593599	[520]	[1026,513,NaN]	4	hSpCas9	negative selection	9643067
40779590	40779613	17	-	27869803	HPAFII	viability after 15 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.22625834803934364	[343]	[770,221,NaN]	2	hSpCas9	negative selection	9643068
40780359	40780382	17	-	27869803	HPAFII	viability after 15 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.28650770664247815	[104]	[139,62,NaN]	-3	hSpCas9	negative selection	9643069
40780422	40780445	17	-	27869803	HPAFII	viability after 15 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.18084781222191182	[164]	[206,124,NaN]	-2	hSpCas9	negative selection	9643070
40782261	40782284	17	-	27869803	HPAFII	viability after 15 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	-0.49761659213785925	[354]	[387,196,NaN]	-5	hSpCas9	negative selection	9643071
40782444	40782467	17	-	27869803	HPAFII	viability after 15 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	0.518799571759063	[131]	[111,259,NaN]	6	hSpCas9	negative selection	9643072
40779493	40779516	17	+	27869803	ASPC1	viability after 36 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.6594541056780459	[1064]	[622,707,459]	6	hSpCas9	negative selection	9725516
40779590	40779613	17	-	27869803	ASPC1	viability after 36 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	0.481662939822354	[922]	[913,238,286]	5	hSpCas9	negative selection	9725517
40780359	40780382	17	-	27869803	ASPC1	viability after 36 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.025291559242019535	[218]	[0,38,154]	0	hSpCas9	negative selection	9725518
40780422	40780445	17	-	27869803	ASPC1	viability after 36 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-0.6483480167780736	[496]	[61,137,121]	-6	hSpCas9	negative selection	9725519
40782261	40782284	17	-	27869803	ASPC1	viability after 36 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.4368238168090888	[626]	[399,69,399]	4	hSpCas9	negative selection	9725520
40782444	40782467	17	-	27869803	ASPC1	viability after 36 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.4746355373582405	[328]	[195,53,24]	-5	hSpCas9	negative selection	9725521
40779493	40779516	17	+	27869803	PATU8988S	viability after 35 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.08622084053545742	[1062]	[449,458,NaN]	1	hSpCas9	negative selection	9807965
40779590	40779613	17	-	27869803	PATU8988S	viability after 35 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-1.759782330891186	[866]	[151,53,NaN]	-8	hSpCas9	negative selection	9807966
40780359	40780382	17	-	27869803	PATU8988S	viability after 35 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.3813362561610594	[264]	[54,108,NaN]	-4	hSpCas9	negative selection	9807967
40780422	40780445	17	-	27869803	PATU8988S	viability after 35 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.030561157595382124	[490]	[194,208,NaN]	0	hSpCas9	negative selection	9807968
40782261	40782284	17	-	27869803	PATU8988S	viability after 35 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	-0.906398062865384	[685]	[104,189,NaN]	-7	hSpCas9	negative selection	9807969
40782444	40782467	17	-	27869803	PATU8988S	viability after 35 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-1.2403408676785816	[418]	[39,102,NaN]	-8	hSpCas9	negative selection	9807970
40779493	40779516	17	+	27869803	PATU8988S	viability after 31 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.22671783337173923	[1062]	[462,537,NaN]	3	hSpCas9	negative selection	9890414
40779590	40779613	17	-	27869803	PATU8988S	viability after 31 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-1.4809933857855808	[866]	[162,73,NaN]	-8	hSpCas9	negative selection	9890415
40780359	40780382	17	-	27869803	PATU8988S	viability after 31 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.17262584886415344	[264]	[47,151,NaN]	-2	hSpCas9	negative selection	9890416
40780422	40780445	17	-	27869803	PATU8988S	viability after 31 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	0.2515233452098973	[490]	[196,278,NaN]	3	hSpCas9	negative selection	9890417
40782261	40782284	17	-	27869803	PATU8988S	viability after 31 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	-0.5904476557796758	[685]	[116,263,NaN]	-6	hSpCas9	negative selection	9890418
40782444	40782467	17	-	27869803	PATU8988S	viability after 31 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-2.585421157340383	[418]	[11,47,NaN]	-9	hSpCas9	negative selection	9890419
40779493	40779516	17	+	27869803	HPAFII	viability after 35 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.8851484203271578	[520]	[417,564,NaN]	6	hSpCas9	negative selection	9972863
40779590	40779613	17	-	27869803	HPAFII	viability after 35 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.6856501224786062	[343]	[183,22,NaN]	-4	hSpCas9	negative selection	9972864
40780359	40780382	17	-	27869803	HPAFII	viability after 35 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.23650730025169397	[104]	[46,42,NaN]	-1	hSpCas9	negative selection	9972865
40780422	40780445	17	-	27869803	HPAFII	viability after 35 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-2.7506783921644615	[164]	[10,13,NaN]	-8	hSpCas9	negative selection	9972866
40782261	40782284	17	-	27869803	HPAFII	viability after 35 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	0.14723853044950763	[354]	[135,269,NaN]	0	hSpCas9	negative selection	9972867
40782444	40782467	17	-	27869803	HPAFII	viability after 35 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.34594358546762516	[131]	[29,77,NaN]	-2	hSpCas9	negative selection	9972868
40779493	40779516	17	+	27869803	HPAFII	viability after 31 days	TTCGCTTACCGTTGCTAAGAGGG	KRT27	ENSG00000171446	0.8708753200184958	[520]	[427,650,NaN]	6	hSpCas9	negative selection	10055312
40779590	40779613	17	-	27869803	HPAFII	viability after 31 days	CAGCAGATCTCTGACGACGCTGG	KRT27	ENSG00000171446	-0.6073768606649921	[343]	[153,96,NaN]	-4	hSpCas9	negative selection	10055313
40780359	40780382	17	-	27869803	HPAFII	viability after 31 days	GACCTTGTGCAGAACGGACCTGG	KRT27	ENSG00000171446	-0.7807376467054152	[104]	[40,26,NaN]	-5	hSpCas9	negative selection	10055314
40780422	40780445	17	-	27869803	HPAFII	viability after 31 days	GCTAGCGCTTCACCAGAGCGTGG	KRT27	ENSG00000171446	-1.9019299062291424	[164]	[30,17,NaN]	-8	hSpCas9	negative selection	10055315
40782261	40782284	17	-	27869803	HPAFII	viability after 31 days	GCCTTCACAGGGAATGAGCACGG	KRT27	ENSG00000171446	-0.374464758072222	[354]	[101,209,NaN]	-3	hSpCas9	negative selection	10055316
40782444	40782467	17	-	27869803	HPAFII	viability after 31 days	AGGAGACTTGGCTCTTGCGGGGG	KRT27	ENSG00000171446	-0.12295403135782834	[131]	[23,115,NaN]	-1	hSpCas9	negative selection	10055317
40782172	40782195	17	-	28162770	P31FUJ	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.08677813561656086	[245]	[306]	0	hSpCas9	negative selection	10181405
40780347	40780370	17	-	28162770	P31FUJ	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.3517902406314657	[239]	[220]	-3	hSpCas9	negative selection	10181406
40779780	40779803	17	+	28162770	P31FUJ	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.24540224119401233	[114]	[113]	-2	hSpCas9	negative selection	10181407
40782363	40782386	17	-	28162770	P31FUJ	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	1.0454989580727256	[46]	[113]	9	hSpCas9	negative selection	10181408
40782312	40782335	17	-	28162770	P31FUJ	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.8152031684964536	[132]	[274]	8	hSpCas9	negative selection	10181409
40782137	40782160	17	-	28162770	P31FUJ	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	0.355259534965664	[154]	[232]	4	hSpCas9	negative selection	10181410
40780419	40780442	17	-	28162770	P31FUJ	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.18973348252249284	[329]	[339]	-2	hSpCas9	negative selection	10181411
40779727	40779750	17	+	28162770	P31FUJ	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	0.05688332950941355	[732]	[895]	0	hSpCas9	negative selection	10181412
40782302	40782325	17	-	28162770	P31FUJ	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.37196877738695794	[216]	[329]	4	hSpCas9	negative selection	10181413
40782260	40782283	17	+	28162770	P31FUJ	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.17816106851328506	[828]	[860]	-2	hSpCas9	negative selection	10181414
40782172	40782195	17	-	28162770	TF1	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	NaN	[NaN]	[329]	1	hSpCas9	negative selection	10350771
40780347	40780370	17	-	28162770	TF1	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	NaN	[NaN]	[246]	1	hSpCas9	negative selection	10350772
40779780	40779803	17	+	28162770	TF1	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	NaN	[NaN]	[41]	1	hSpCas9	negative selection	10350773
40782363	40782386	17	-	28162770	TF1	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10350774
40782312	40782335	17	-	28162770	TF1	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	NaN	[NaN]	[94]	1	hSpCas9	negative selection	10350775
40782137	40782160	17	-	28162770	TF1	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	NaN	[NaN]	[118]	1	hSpCas9	negative selection	10350776
40780419	40780442	17	-	28162770	TF1	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	NaN	[NaN]	[240]	1	hSpCas9	negative selection	10350777
40779727	40779750	17	+	28162770	TF1	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	NaN	[NaN]	[328]	1	hSpCas9	negative selection	10350778
40782302	40782325	17	-	28162770	TF1	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	NaN	[NaN]	[371]	1	hSpCas9	negative selection	10350779
40782260	40782283	17	+	28162770	TF1	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	NaN	[NaN]	[578]	1	hSpCas9	negative selection	10350780
40782172	40782195	17	-	28162770	SKM1	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-1.3074285251922473	[90]	[64]	-7	hSpCas9	negative selection	10520137
40780347	40780370	17	-	28162770	SKM1	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-1.0146467759644013	[63]	[55]	-6	hSpCas9	negative selection	10520138
40779780	40779803	17	+	28162770	SKM1	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.33657487085176363	[34]	[48]	-3	hSpCas9	negative selection	10520139
40782363	40782386	17	-	28162770	SKM1	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	0.8256965580471134	[14]	[46]	7	hSpCas9	negative selection	10520140
40782312	40782335	17	-	28162770	SKM1	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.3314727826397126	[48]	[108]	3	hSpCas9	negative selection	10520141
40782137	40782160	17	-	28162770	SKM1	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.8220016980220053	[63]	[63]	-6	hSpCas9	negative selection	10520142
40780419	40780442	17	-	28162770	SKM1	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.00360850451195327	[92]	[163]	0	hSpCas9	negative selection	10520143
40779727	40779750	17	+	28162770	SKM1	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	0.31644507194713856	[138]	[305]	3	hSpCas9	negative selection	10520144
40782302	40782325	17	-	28162770	SKM1	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.38950240717170626	[56]	[131]	4	hSpCas9	negative selection	10520145
40782260	40782283	17	+	28162770	SKM1	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.1637225196579284	[210]	[332]	-1	hSpCas9	negative selection	10520146
40782172	40782195	17	-	28162770	SKM1	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-1.3074285251922473	[90]	[64]	-7	hSpCas9	negative selection	10689503
40780347	40780370	17	-	28162770	SKM1	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-1.0146467759644013	[63]	[55]	-6	hSpCas9	negative selection	10689504
40779780	40779803	17	+	28162770	SKM1	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.33657487085176363	[34]	[48]	-3	hSpCas9	negative selection	10689505
40782363	40782386	17	-	28162770	SKM1	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	0.8256965580471134	[14]	[46]	7	hSpCas9	negative selection	10689506
40782312	40782335	17	-	28162770	SKM1	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.3314727826397126	[48]	[108]	3	hSpCas9	negative selection	10689507
40782137	40782160	17	-	28162770	SKM1	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.8220016980220053	[63]	[63]	-6	hSpCas9	negative selection	10689508
40780419	40780442	17	-	28162770	SKM1	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.00360850451195327	[92]	[163]	0	hSpCas9	negative selection	10689509
40779727	40779750	17	+	28162770	SKM1	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	0.31644507194713856	[138]	[305]	3	hSpCas9	negative selection	10689510
40782302	40782325	17	-	28162770	SKM1	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.38950240717170626	[56]	[131]	4	hSpCas9	negative selection	10689511
40782260	40782283	17	+	28162770	SKM1	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.1637225196579284	[210]	[332]	-1	hSpCas9	negative selection	10689512
40782172	40782195	17	-	28162770	PL21	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.0836806379019373	[244]	[112]	0	hSpCas9	negative selection	10858869
40780347	40780370	17	-	28162770	PL21	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.0916265098877897	[141]	[57]	0	hSpCas9	negative selection	10858870
40779780	40779803	17	+	28162770	PL21	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-1.2817293932677325	[161]	[28]	-7	hSpCas9	negative selection	10858871
40782363	40782386	17	-	28162770	PL21	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-1.607215307568284	[90]	[12]	-8	hSpCas9	negative selection	10858872
40782312	40782335	17	-	28162770	PL21	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.3521427079343702	[125]	[69]	3	hSpCas9	negative selection	10858873
40782137	40782160	17	-	28162770	PL21	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.2555398692868695	[191]	[69]	-2	hSpCas9	negative selection	10858874
40780419	40780442	17	-	28162770	PL21	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	0.04115009072816339	[229]	[102]	0	hSpCas9	negative selection	10858875
40779727	40779750	17	+	28162770	PL21	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.09231127932120864	[435]	[177]	0	hSpCas9	negative selection	10858876
40782302	40782325	17	-	28162770	PL21	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	-0.3129299677500504	[136]	[47]	-2	hSpCas9	negative selection	10858877
40782260	40782283	17	+	28162770	PL21	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	0.1009642093984846	[571]	[266]	0	hSpCas9	negative selection	10858878
40782172	40782195	17	-	28162770	P31FUJ	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.08677813561656086	[245]	[306]	0	hSpCas9	negative selection	11028235
40780347	40780370	17	-	28162770	P31FUJ	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.3517902406314657	[239]	[220]	-3	hSpCas9	negative selection	11028236
40779780	40779803	17	+	28162770	P31FUJ	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.24540224119401233	[114]	[113]	-2	hSpCas9	negative selection	11028237
40782363	40782386	17	-	28162770	P31FUJ	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	1.0454989580727256	[46]	[113]	9	hSpCas9	negative selection	11028238
40782312	40782335	17	-	28162770	P31FUJ	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.8152031684964536	[132]	[274]	8	hSpCas9	negative selection	11028239
40782137	40782160	17	-	28162770	P31FUJ	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	0.355259534965664	[154]	[232]	4	hSpCas9	negative selection	11028240
40780419	40780442	17	-	28162770	P31FUJ	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.18973348252249284	[329]	[339]	-2	hSpCas9	negative selection	11028241
40779727	40779750	17	+	28162770	P31FUJ	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	0.05688332950941355	[732]	[895]	0	hSpCas9	negative selection	11028242
40782302	40782325	17	-	28162770	P31FUJ	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.37196877738695794	[216]	[329]	4	hSpCas9	negative selection	11028243
40782260	40782283	17	+	28162770	P31FUJ	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.17816106851328506	[828]	[860]	-2	hSpCas9	negative selection	11028244
40782172	40782195	17	-	28162770	OCIAML5	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-1.2222498343585804	[189]	[146]	-6	hSpCas9	negative selection	11197601
40780347	40780370	17	-	28162770	OCIAML5	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	0.05899970071571464	[91]	[172]	0	hSpCas9	negative selection	11197602
40779780	40779803	17	+	28162770	OCIAML5	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.9045339907581325	[55]	[53]	-5	hSpCas9	negative selection	11197603
40782363	40782386	17	-	28162770	OCIAML5	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-0.04471164880639278	[31]	[55]	0	hSpCas9	negative selection	11197604
40782312	40782335	17	-	28162770	OCIAML5	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.4467779109103239	[62]	[154]	4	hSpCas9	negative selection	11197605
40782137	40782160	17	-	28162770	OCIAML5	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-1.5657623857073562	[122]	[74]	-7	hSpCas9	negative selection	11197606
40780419	40780442	17	-	28162770	OCIAML5	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.6148413513798084	[234]	[276]	-4	hSpCas9	negative selection	11197607
40779727	40779750	17	+	28162770	OCIAML5	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.1201847298999541	[397]	[660]	-1	hSpCas9	negative selection	11197608
40782302	40782325	17	-	28162770	OCIAML5	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	-0.9337503684577051	[108]	[102]	-5	hSpCas9	negative selection	11197609
40782260	40782283	17	+	28162770	OCIAML5	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.719244890622567	[476]	[522]	-5	hSpCas9	negative selection	11197610
40782172	40782195	17	-	28162770	EOL1	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.41640086790020936	[447]	[314]	4	hSpCas9	negative selection	11366967
40780347	40780370	17	-	28162770	EOL1	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	0.4708298041276309	[251]	[183]	4	hSpCas9	negative selection	11366968
40779780	40779803	17	+	28162770	EOL1	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-1.179788888244201	[300]	[69]	-7	hSpCas9	negative selection	11366969
40782363	40782386	17	-	28162770	EOL1	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-1.004369130367983	[98]	[25]	-6	hSpCas9	negative selection	11366970
40782312	40782335	17	-	28162770	EOL1	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.8574335757119975	[263]	[251]	7	hSpCas9	negative selection	11366971
40782137	40782160	17	-	28162770	EOL1	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	0.08454365576911517	[323]	[180]	0	hSpCas9	negative selection	11366972
40780419	40780442	17	-	28162770	EOL1	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	1.748776512192535	[339]	[601]	9	hSpCas9	negative selection	11366973
40779727	40779750	17	+	28162770	EOL1	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	0.40886809603469687	[558]	[390]	4	hSpCas9	negative selection	11366974
40782302	40782325	17	-	28162770	EOL1	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.3568632622812139	[165]	[111]	3	hSpCas9	negative selection	11366975
40782260	40782283	17	+	28162770	EOL1	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.1255160664802799	[732]	[353]	-1	hSpCas9	negative selection	11366976
40782172	40782195	17	-	28162770	MOLM13	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.5040088073512305	[354]	[363]	4	hSpCas9	negative selection	11536333
40780347	40780370	17	-	28162770	MOLM13	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	0.5833665989645148	[287]	[311]	4	hSpCas9	negative selection	11536334
40779780	40779803	17	+	28162770	MOLM13	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-1.7337444796250716	[206]	[44]	-7	hSpCas9	negative selection	11536335
40782363	40782386	17	-	28162770	MOLM13	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-1.3394655405130254	[90]	[25]	-6	hSpCas9	negative selection	11536336
40782312	40782335	17	-	28162770	MOLM13	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	1.2439245403893773	[152]	[261]	8	hSpCas9	negative selection	11536337
40782137	40782160	17	-	28162770	MOLM13	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.17345558907409606	[286]	[183]	-1	hSpCas9	negative selection	11536338
40780419	40780442	17	-	28162770	MOLM13	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	0.07215243822467121	[395]	[300]	0	hSpCas9	negative selection	11536339
40779727	40779750	17	+	28162770	MOLM13	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.3464807163072341	[669]	[380]	-2	hSpCas9	negative selection	11536340
40782302	40782325	17	-	28162770	MOLM13	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	1.5347960401746934	[157]	[330]	9	hSpCas9	negative selection	11536341
40782260	40782283	17	+	28162770	MOLM13	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.49887428898148944	[943]	[482]	-3	hSpCas9	negative selection	11536342
40782172	40782195	17	-	28162770	HEL	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.5577182475860505	[331]	[312]	5	hSpCas9	negative selection	11705699
40780347	40780370	17	-	28162770	HEL	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	0.3824239275201552	[211]	[176]	3	hSpCas9	negative selection	11705700
40779780	40779803	17	+	28162770	HEL	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.6542429057567745	[171]	[69]	-4	hSpCas9	negative selection	11705701
40782363	40782386	17	-	28162770	HEL	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	0.7523633231748551	[75]	[81]	6	hSpCas9	negative selection	11705702
40782312	40782335	17	-	28162770	HEL	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.3332555034796396	[201]	[162]	2	hSpCas9	negative selection	11705703
40782137	40782160	17	-	28162770	HEL	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-1.5653693633298436	[267]	[57]	-7	hSpCas9	negative selection	11705704
40780419	40780442	17	-	28162770	HEL	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.35726116799964314	[283]	[141]	-3	hSpCas9	negative selection	11705705
40779727	40779750	17	+	28162770	HEL	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.605860483569868	[536]	[225]	-4	hSpCas9	negative selection	11705706
40782302	40782325	17	-	28162770	HEL	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.503840726178669	[206]	[187]	4	hSpCas9	negative selection	11705707
40782260	40782283	17	+	28162770	HEL	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.9736561765574565	[695]	[226]	-6	hSpCas9	negative selection	11705708
40782172	40782195	17	-	28162770	MV411	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-0.8282267191492969	[273]	[129]	-5	hSpCas9	negative selection	11875065
40780347	40780370	17	-	28162770	MV411	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.6683494453141393	[182]	[96]	-5	hSpCas9	negative selection	11875066
40779780	40779803	17	+	28162770	MV411	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-1.2699616661257462	[145]	[50]	-7	hSpCas9	negative selection	11875067
40782363	40782386	17	-	28162770	MV411	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-1.2325553903368387	[52]	[18]	-7	hSpCas9	negative selection	11875068
40782312	40782335	17	-	28162770	MV411	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.3092768046006381	[136]	[142]	2	hSpCas9	negative selection	11875069
40782137	40782160	17	-	28162770	MV411	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.4943693064529301	[198]	[118]	-4	hSpCas9	negative selection	11875070
40780419	40780442	17	-	28162770	MV411	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	0.2402059815516996	[199]	[198]	2	hSpCas9	negative selection	11875071
40779727	40779750	17	+	28162770	MV411	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.8870126489896055	[471]	[214]	-6	hSpCas9	negative selection	11875072
40782302	40782325	17	-	28162770	MV411	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	-1.325452117637806	[118]	[39]	-7	hSpCas9	negative selection	11875073
40782260	40782283	17	+	28162770	MV411	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-1.4034882123167396	[536]	[170]	-7	hSpCas9	negative selection	11875074
40782172	40782195	17	-	28162770	MONOMAC1	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-0.514519036915724	[161]	[129]	-4	hSpCas9	negative selection	12044431
40780347	40780370	17	-	28162770	MONOMAC1	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	0.5843228664651059	[95]	[164]	6	hSpCas9	negative selection	12044432
40779780	40779803	17	+	28162770	MONOMAC1	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	0.46592816566287565	[59]	[94]	4	hSpCas9	negative selection	12044433
40782363	40782386	17	-	28162770	MONOMAC1	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	0.4210925175968019	[42]	[65]	4	hSpCas9	negative selection	12044434
40782312	40782335	17	-	28162770	MONOMAC1	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.5483903258548488	[101]	[170]	5	hSpCas9	negative selection	12044435
40782137	40782160	17	-	28162770	MONOMAC1	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.518964941946916	[139]	[111]	-4	hSpCas9	negative selection	12044436
40780419	40780442	17	-	28162770	MONOMAC1	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-0.33555671114098173	[141]	[128]	-3	hSpCas9	negative selection	12044437
40779727	40779750	17	+	28162770	MONOMAC1	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.8951134278321649	[304]	[187]	-6	hSpCas9	negative selection	12044438
40782302	40782325	17	-	28162770	MONOMAC1	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	0.871858234151514	[91]	[192]	7	hSpCas9	negative selection	12044439
40782260	40782283	17	+	28162770	MONOMAC1	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	0.12795755087559213	[375]	[470]	1	hSpCas9	negative selection	12044440
40782172	40782195	17	-	28162770	OCIAML2	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	0.1370527519790785	[41]	[255]	1	hSpCas9	negative selection	12213797
40780347	40780370	17	-	28162770	OCIAML2	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.3960828718771072	[32]	[138]	-3	hSpCas9	negative selection	12213798
40779780	40779803	17	+	28162770	OCIAML2	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	0.08736562787872548	[26]	[158]	0	hSpCas9	negative selection	12213799
40782363	40782386	17	-	28162770	OCIAML2	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-1.7925579201295232	[14]	[23]	-8	hSpCas9	negative selection	12213800
40782312	40782335	17	-	28162770	OCIAML2	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.11433267547899495	[25]	[155]	1	hSpCas9	negative selection	12213801
40782137	40782160	17	-	28162770	OCIAML2	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	-0.39262731324088795	[35]	[151]	-3	hSpCas9	negative selection	12213802
40780419	40780442	17	-	28162770	OCIAML2	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	0.09953567355091453	[48]	[290]	0	hSpCas9	negative selection	12213803
40779727	40779750	17	+	28162770	OCIAML2	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.5204609811941677	[80]	[312]	-4	hSpCas9	negative selection	12213804
40782302	40782325	17	-	28162770	OCIAML2	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	-0.8097184712877066	[36]	[116]	-5	hSpCas9	negative selection	12213805
40782260	40782283	17	+	28162770	OCIAML2	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	-0.881137666040491	[105]	[318]	-6	hSpCas9	negative selection	12213806
40782172	40782195	17	-	28162770	OCIAML3	viability	GAATGTTCGAGCCCTAGAGGAGG	KRT27	ENSG00000171446	-1.0441733630066088	[96]	[141]	-6	hSpCas9	negative selection	12383163
40780347	40780370	17	-	28162770	OCIAML3	viability	AACGGACCTGGAGATCCAGCTGG	KRT27	ENSG00000171446	-0.36371002090236915	[51]	[121]	-3	hSpCas9	negative selection	12383164
40779780	40779803	17	+	28162770	OCIAML3	viability	GAACCGTGAGGTCTACCCCGGGG	KRT27	ENSG00000171446	-0.4565041165742283	[29]	[65]	-4	hSpCas9	negative selection	12383165
40782363	40782386	17	-	28162770	OCIAML3	viability	GGTGTGCCAGGCATTGGAAGTGG	KRT27	ENSG00000171446	-0.2858853449618315	[20]	[51]	-2	hSpCas9	negative selection	12383166
40782312	40782335	17	-	28162770	OCIAML3	viability	TCTGCAGGAGGCTATGGCGGAGG	KRT27	ENSG00000171446	0.9570075284736552	[42]	[251]	8	hSpCas9	negative selection	12383167
40782137	40782160	17	-	28162770	OCIAML3	viability	TGGAGCAGAAGATCAAGGGGTGG	KRT27	ENSG00000171446	0.7517671965175667	[47]	[243]	6	hSpCas9	negative selection	12383168
40780419	40780442	17	-	28162770	OCIAML3	viability	AGCGCTTCACCAGAGCGTGGAGG	KRT27	ENSG00000171446	-1.093578649814675	[81]	[115]	-7	hSpCas9	negative selection	12383169
40779727	40779750	17	+	28162770	OCIAML3	viability	CCTGCGGTTCTGCTCTGCGAGGG	KRT27	ENSG00000171446	-0.121419118483161	[128]	[357]	-1	hSpCas9	negative selection	12383170
40782302	40782325	17	-	28162770	OCIAML3	viability	GCTATGGCGGAGGTCTGGGCGGG	KRT27	ENSG00000171446	1.5837157316785564	[40]	[370]	9	hSpCas9	negative selection	12383171
40782260	40782283	17	+	28162770	OCIAML3	viability	GCCGTGCTCATTCCCTGTGAAGG	KRT27	ENSG00000171446	0.21039999768310413	[139]	[488]	2	hSpCas9	negative selection	12383172