Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3884
• Symbol:KRT33B
• Description:keratin 33B

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT33B

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
41365484	41365507	17	-	26472758	Jiyoye	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.30589204566869177	[117]	[109]	2	hSpCas9	negative selection	86442
41365484	41365507	CHR_HSCHR17_1_CTG4	-	26472758	Jiyoye	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000263012	0.30589204566869177	[117]	[109]	2	hSpCas9	negative selection	86443
41363869	41363892	17	+	26472758	Jiyoye	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	1.4630286162393908	[37]	[78]	8	hSpCas9	negative selection	86444
41363869	41363892	CHR_HSCHR17_1_CTG4	+	26472758	Jiyoye	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000263012	1.4630286162393908	[37]	[78]	8	hSpCas9	negative selection	86445
41366616	41366639	CHR_HSCHR17_1_CTG4	-	26472758	Jiyoye	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000263012	1.673187487139563	[120]	[290]	8	hSpCas9	negative selection	86446
41366616	41366639	17	-	26472758	Jiyoye	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	1.673187487139563	[120]	[290]	8	hSpCas9	negative selection	86447
41366595	41366618	17	-	26472758	Jiyoye	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	1.3695049635398184	[96]	[188]	7	hSpCas9	negative selection	86448
41366595	41366618	CHR_HSCHR17_1_CTG4	-	26472758	Jiyoye	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000263012	1.3695049635398184	[96]	[188]	7	hSpCas9	negative selection	86449
41369618	41369641	CHR_HSCHR17_1_CTG4	+	26472758	Jiyoye	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000263012	0.8865591258733319	[580]	[809]	6	hSpCas9	negative selection	86450
41369618	41369641	17	+	26472758	Jiyoye	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.8865591258733319	[580]	[809]	6	hSpCas9	negative selection	86451
41366517	41366540	17	-	26472758	Jiyoye	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.2967513918122229	[94]	[87]	2	hSpCas9	negative selection	86452
41366517	41366540	CHR_HSCHR17_1_CTG4	-	26472758	Jiyoye	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000263012	0.2967513918122229	[94]	[87]	2	hSpCas9	negative selection	86453
41369730	41369753	17	+	26472758	Jiyoye	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.3752913204860874	[182]	[178]	3	hSpCas9	negative selection	86456
41369730	41369753	CHR_HSCHR17_1_CTG4	+	26472758	Jiyoye	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000263012	0.3752913204860874	[182]	[178]	3	hSpCas9	negative selection	86457
41367943	41367966	CHR_HSCHR17_1_CTG4	+	26472758	Jiyoye	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000263012	-0.4918957096433457	[137]	[73]	-4	hSpCas9	negative selection	86458
41367943	41367966	17	+	26472758	Jiyoye	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.4918957096433457	[137]	[73]	-4	hSpCas9	negative selection	86459
41367916	41367939	CHR_HSCHR17_1_CTG4	+	26472758	Jiyoye	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000263012	-0.48590941457761466	[129]	[69]	-3	hSpCas9	negative selection	86460
41367916	41367939	17	+	26472758	Jiyoye	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	-0.48590941457761466	[129]	[69]	-3	hSpCas9	negative selection	86461
41366457	41366480	CHR_HSCHR17_1_CTG4	+	26472758	Jiyoye	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000263012	0.704157119263005	[34]	[42]	5	hSpCas9	negative selection	86462
41366457	41366480	17	+	26472758	Jiyoye	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.704157119263005	[34]	[42]	5	hSpCas9	negative selection	86463
41365484	41365507	17	-	26472758	KBM7	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-0.18976891951733169	[615,363]	[203,191]	-2	hSpCas9	negative selection	277560
41365484	41365507	CHR_HSCHR17_1_CTG4	-	26472758	KBM7	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000263012	-0.18976891951733169	[615,363]	[203,191]	-2	hSpCas9	negative selection	277561
41363869	41363892	17	+	26472758	KBM7	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.8480117064767576	[367,354]	[118,72]	-6	hSpCas9	negative selection	277562
41363869	41363892	CHR_HSCHR17_1_CTG4	+	26472758	KBM7	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000263012	-0.8480117064767576	[367,354]	[118,72]	-6	hSpCas9	negative selection	277563
41366616	41366639	CHR_HSCHR17_1_CTG4	-	26472758	KBM7	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000263012	0.5605375111040988	[994,832]	[703,565]	6	hSpCas9	negative selection	277564
41366616	41366639	17	-	26472758	KBM7	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.5605375111040988	[994,832]	[703,565]	6	hSpCas9	negative selection	277565
41366595	41366618	17	-	26472758	KBM7	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.7832276782621	[892,639]	[597,625]	8	hSpCas9	negative selection	277566
41366595	41366618	CHR_HSCHR17_1_CTG4	-	26472758	KBM7	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000263012	0.7832276782621	[892,639]	[597,625]	8	hSpCas9	negative selection	277567
41369618	41369641	CHR_HSCHR17_1_CTG4	+	26472758	KBM7	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000263012	0.3362301790638158	[3219,2572]	[1725,1691]	3	hSpCas9	negative selection	277568
41369618	41369641	17	+	26472758	KBM7	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.3362301790638158	[3219,2572]	[1725,1691]	3	hSpCas9	negative selection	277569
41366517	41366540	17	-	26472758	KBM7	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.09314404284940254	[653,364]	[232,263]	0	hSpCas9	negative selection	277570
41366517	41366540	CHR_HSCHR17_1_CTG4	-	26472758	KBM7	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000263012	0.09314404284940254	[653,364]	[232,263]	0	hSpCas9	negative selection	277571
41369730	41369753	17	+	26472758	KBM7	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.6395373657527392	[1145,893]	[876,619]	7	hSpCas9	negative selection	277574
41369730	41369753	CHR_HSCHR17_1_CTG4	+	26472758	KBM7	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000263012	0.6395373657527392	[1145,893]	[876,619]	7	hSpCas9	negative selection	277575
41367943	41367966	CHR_HSCHR17_1_CTG4	+	26472758	KBM7	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000263012	0.4423215059946135	[555,485]	[422,250]	5	hSpCas9	negative selection	277576
41367943	41367966	17	+	26472758	KBM7	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.4423215059946135	[555,485]	[422,250]	5	hSpCas9	negative selection	277577
41367916	41367939	CHR_HSCHR17_1_CTG4	+	26472758	KBM7	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000263012	0.34904927577940054	[635,570]	[281,431]	3	hSpCas9	negative selection	277578
41367916	41367939	17	+	26472758	KBM7	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.34904927577940054	[635,570]	[281,431]	3	hSpCas9	negative selection	277579
41366457	41366480	CHR_HSCHR17_1_CTG4	+	26472758	KBM7	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000263012	0.8422698068178064	[285,203]	[203,203]	8	hSpCas9	negative selection	277580
41366457	41366480	17	+	26472758	KBM7	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.8422698068178064	[285,203]	[203,203]	8	hSpCas9	negative selection	277581
41365484	41365507	17	-	26472758	Raji	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-0.3368349893171908	[282]	[51]	-3	hSpCas9	negative selection	468678
41365484	41365507	CHR_HSCHR17_1_CTG4	-	26472758	Raji	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000263012	-0.3368349893171908	[282]	[51]	-3	hSpCas9	negative selection	468679
41363869	41363892	17	+	26472758	Raji	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-1.1252772214166755	[187]	[19]	-7	hSpCas9	negative selection	468680
41363869	41363892	CHR_HSCHR17_1_CTG4	+	26472758	Raji	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000263012	-1.1252772214166755	[187]	[19]	-7	hSpCas9	negative selection	468681
41366616	41366639	CHR_HSCHR17_1_CTG4	-	26472758	Raji	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000263012	0.7328408143228153	[362]	[139]	7	hSpCas9	negative selection	468682
41366616	41366639	17	-	26472758	Raji	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.7328408143228153	[362]	[139]	7	hSpCas9	negative selection	468683
41366595	41366618	17	-	26472758	Raji	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.2929391885296758	[407]	[115]	2	hSpCas9	negative selection	468684
41366595	41366618	CHR_HSCHR17_1_CTG4	-	26472758	Raji	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000263012	0.2929391885296758	[407]	[115]	2	hSpCas9	negative selection	468685
41369618	41369641	CHR_HSCHR17_1_CTG4	+	26472758	Raji	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000263012	0.26341154579621495	[1216]	[338]	2	hSpCas9	negative selection	468686
41369618	41369641	17	+	26472758	Raji	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.26341154579621495	[1216]	[338]	2	hSpCas9	negative selection	468687
41366517	41366540	17	-	26472758	Raji	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	-0.08106155403951071	[195]	[42]	0	hSpCas9	negative selection	468688
41366517	41366540	CHR_HSCHR17_1_CTG4	-	26472758	Raji	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000263012	-0.08106155403951071	[195]	[42]	0	hSpCas9	negative selection	468689
41369730	41369753	17	+	26472758	Raji	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	-0.3683498955927983	[533]	[95]	-3	hSpCas9	negative selection	468692
41369730	41369753	CHR_HSCHR17_1_CTG4	+	26472758	Raji	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000263012	-0.3683498955927983	[533]	[95]	-3	hSpCas9	negative selection	468693
41367943	41367966	CHR_HSCHR17_1_CTG4	+	26472758	Raji	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000263012	-0.02647221136119099	[315]	[71]	0	hSpCas9	negative selection	468694
41367943	41367966	17	+	26472758	Raji	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.02647221136119099	[315]	[71]	0	hSpCas9	negative selection	468695
41367916	41367939	CHR_HSCHR17_1_CTG4	+	26472758	Raji	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000263012	0.4394595856370448	[339]	[106]	4	hSpCas9	negative selection	468696
41367916	41367939	17	+	26472758	Raji	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.4394595856370448	[339]	[106]	4	hSpCas9	negative selection	468697
41366457	41366480	CHR_HSCHR17_1_CTG4	+	26472758	Raji	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000263012	0.9539090547118813	[108]	[48]	8	hSpCas9	negative selection	468698
41366457	41366480	17	+	26472758	Raji	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.9539090547118813	[108]	[48]	8	hSpCas9	negative selection	468699
41365484	41365507	17	-	26472758	K562	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.3367827458151066	[362]	[386]	2	hSpCas9	negative selection	659796
41365484	41365507	CHR_HSCHR17_1_CTG4	-	26472758	K562	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000263012	0.3367827458151066	[362]	[386]	2	hSpCas9	negative selection	659797
41363869	41363892	17	+	26472758	K562	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.3037438548517575	[328]	[224]	-2	hSpCas9	negative selection	659798
41363869	41363892	CHR_HSCHR17_1_CTG4	+	26472758	K562	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000263012	-0.3037438548517575	[328]	[224]	-2	hSpCas9	negative selection	659799
41366616	41366639	CHR_HSCHR17_1_CTG4	-	26472758	K562	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000263012	0.9847226072578754	[776]	[1297]	8	hSpCas9	negative selection	659800
41366616	41366639	17	-	26472758	K562	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.9847226072578754	[776]	[1297]	8	hSpCas9	negative selection	659801
41366595	41366618	17	-	26472758	K562	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.08075924046213656	[717]	[640]	0	hSpCas9	negative selection	659802
41366595	41366618	CHR_HSCHR17_1_CTG4	-	26472758	K562	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000263012	0.08075924046213656	[717]	[640]	0	hSpCas9	negative selection	659803
41369618	41369641	CHR_HSCHR17_1_CTG4	+	26472758	K562	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000263012	0.9042118990607757	[2084]	[3293]	7	hSpCas9	negative selection	659804
41369618	41369641	17	+	26472758	K562	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.9042118990607757	[2084]	[3293]	7	hSpCas9	negative selection	659805
41366517	41366540	17	-	26472758	K562	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	-0.2045661035357345	[429]	[314]	-1	hSpCas9	negative selection	659806
41366517	41366540	CHR_HSCHR17_1_CTG4	-	26472758	K562	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000263012	-0.2045661035357345	[429]	[314]	-1	hSpCas9	negative selection	659807
41369730	41369753	17	+	26472758	K562	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.7287188893824045	[731]	[1023]	6	hSpCas9	negative selection	659810
41369730	41369753	CHR_HSCHR17_1_CTG4	+	26472758	K562	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000263012	0.7287188893824045	[731]	[1023]	6	hSpCas9	negative selection	659811
41367943	41367966	CHR_HSCHR17_1_CTG4	+	26472758	K562	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000263012	0.6654549675667338	[359]	[481]	5	hSpCas9	negative selection	659812
41367943	41367966	17	+	26472758	K562	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.6654549675667338	[359]	[481]	5	hSpCas9	negative selection	659813
41367916	41367939	CHR_HSCHR17_1_CTG4	+	26472758	K562	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000263012	0.5299605329098102	[529]	[645]	4	hSpCas9	negative selection	659814
41367916	41367939	17	+	26472758	K562	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.5299605329098102	[529]	[645]	4	hSpCas9	negative selection	659815
41366457	41366480	CHR_HSCHR17_1_CTG4	+	26472758	K562	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000263012	1.4249909733082677	[149]	[339]	9	hSpCas9	negative selection	659816
41366457	41366480	17	+	26472758	K562	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	1.4249909733082677	[149]	[339]	9	hSpCas9	negative selection	659817
41363827	41363850	17	+	26627737	DLD1	viability	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	1.3869992124141775	[142]	[78,176,99]	9	hSpCas9	negative selection	797668
41363855	41363878	17	+	26627737	DLD1	viability	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.023987649424692226	[1598]	[510,513,500]	0	hSpCas9	negative selection	797669
41363887	41363910	17	+	26627737	DLD1	viability	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	1.0240119479459995	[140]	[64,120,84]	8	hSpCas9	negative selection	797670
41363827	41363850	17	+	26627737	GBM cells	viability after 5 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.14749022802578826	[233]	[139,137]	2	hSpCas9	negative selection	879983
41363855	41363878	17	+	26627737	GBM cells	viability after 5 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.15761290101939318	[610]	[332,397]	2	hSpCas9	negative selection	879984
41363887	41363910	17	+	26627737	GBM cells	viability after 5 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	0.6006900405895917	[82]	[79,54]	8	hSpCas9	negative selection	879985
41363827	41363850	17	+	26627737	GBM cells	viability after 13 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.5188334426084356	[233]	[214,154]	6	hSpCas9	negative selection	962298
41363855	41363878	17	+	26627737	GBM cells	viability after 13 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.11763052748374192	[610]	[330,382]	1	hSpCas9	negative selection	962299
41363887	41363910	17	+	26627737	GBM cells	viability after 13 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	0.31043510037062916	[82]	[94,23]	4	hSpCas9	negative selection	962300
41363827	41363850	17	+	26627737	GBM cells	viability after 21 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	1.2716501025559659	[233]	[284,326]	9	hSpCas9	negative selection	1044613
41363855	41363878	17	+	26627737	GBM cells	viability after 21 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.46507336239264174	[610]	[464,451]	5	hSpCas9	negative selection	1044614
41363887	41363910	17	+	26627737	GBM cells	viability after 21 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	0.538127322790666	[82]	[65,64]	5	hSpCas9	negative selection	1044615
41363827	41363850	17	+	26627737	RPE1	viability after 9 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.0015906595744022978	[584]	[154,218]	0	hSpCas9	negative selection	1126928
41363855	41363878	17	+	26627737	RPE1	viability after 9 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.6391581902205683	[2076]	[927,1121]	4	hSpCas9	negative selection	1126929
41363887	41363910	17	+	26627737	RPE1	viability after 9 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.4633413771999959	[458]	[122,79]	-3	hSpCas9	negative selection	1126930
41363827	41363850	17	+	26627737	RPE1	viability after 12 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.4433581350324037	[584]	[220,205]	3	hSpCas9	negative selection	1209243
41363855	41363878	17	+	26627737	RPE1	viability after 12 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.526518677999873	[2076]	[694,918]	3	hSpCas9	negative selection	1209244
41363887	41363910	17	+	26627737	RPE1	viability after 12 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.6018161990662212	[458]	[38,125]	-4	hSpCas9	negative selection	1209245
41363827	41363850	17	+	26627737	RPE1	viability after 15 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.10485995635112916	[584]	[47,255]	0	hSpCas9	negative selection	1291558
41363855	41363878	17	+	26627737	RPE1	viability after 15 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.4992171948123303	[2076]	[1029,637]	3	hSpCas9	negative selection	1291559
41363887	41363910	17	+	26627737	RPE1	viability after 15 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	0.14532865321193544	[458]	[165,121]	1	hSpCas9	negative selection	1291560
41363827	41363850	17	+	26627737	RPE1	viability after 18 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.04474521638947543	[584]	[139,166]	0	hSpCas9	negative selection	1373873
41363855	41363878	17	+	26627737	RPE1	viability after 18 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.5236115392076959	[2076]	[667,952]	3	hSpCas9	negative selection	1373874
41363887	41363910	17	+	26627737	RPE1	viability after 18 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-1.5308764845116474	[458]	[38,46]	-7	hSpCas9	negative selection	1373875
41363827	41363850	17	+	26627737	HeLa	viability after 8 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.42491127088089625	[301]	[211,102,218]	4	hSpCas9	negative selection	1456188
41363855	41363878	17	+	26627737	HeLa	viability after 8 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.1740208652879165	[1174]	[667,630,459]	1	hSpCas9	negative selection	1456189
41363887	41363910	17	+	26627737	HeLa	viability after 8 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.3770956198534139	[265]	[66,98,95]	-4	hSpCas9	negative selection	1456190
41363827	41363850	17	+	26627737	HeLa	viability after 12 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.08323861367000568	[301]	[111,157,78]	0	hSpCas9	negative selection	1538503
41363855	41363878	17	+	26627737	HeLa	viability after 12 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.32626119719647284	[1174]	[732,561,539]	3	hSpCas9	negative selection	1538504
41363887	41363910	17	+	26627737	HeLa	viability after 12 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	0.06908884433252133	[265]	[57,136,146]	0	hSpCas9	negative selection	1538505
41363827	41363850	17	+	26627737	HeLa	viability after 15 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.450288915675383	[301]	[61,109,98]	-4	hSpCas9	negative selection	1620818
41363855	41363878	17	+	26627737	HeLa	viability after 15 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.4983671959673346	[1174]	[704,582,743]	4	hSpCas9	negative selection	1620819
41363887	41363910	17	+	26627737	HeLa	viability after 15 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.11705763354307641	[265]	[136,50,111]	-1	hSpCas9	negative selection	1620820
41363827	41363850	17	+	26627737	HeLa	viability after 18 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.5063092095135601	[301]	[38,85,98]	-4	hSpCas9	negative selection	1703133
41363855	41363878	17	+	26627737	HeLa	viability after 18 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.5066596645679737	[1174]	[485,475,743]	4	hSpCas9	negative selection	1703134
41363887	41363910	17	+	26627737	HeLa	viability after 18 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.07681483012999857	[265]	[95,43,111]	0	hSpCas9	negative selection	1703135
41363827	41363850	17	+	26627737	HCT116	viability after 6 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	1.3786136201459136	[171]	[88,59]	7	hSpCas9	negative selection	1785448
41363855	41363878	17	+	26627737	HCT116	viability after 6 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.902483002356145	[1666]	[456,507]	5	hSpCas9	negative selection	1785449
41363887	41363910	17	+	26627737	HCT116	viability after 6 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-1.7256559924754427	[236]	[18,6]	-7	hSpCas9	negative selection	1785450
41363827	41363850	17	+	26627737	HCT116	viability after 8 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.08781065026418211	[252]	[162,154,126]	1	hSpCas9	negative selection	1867763
41363855	41363878	17	+	26627737	HCT116	viability after 8 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.06266880481964221	[927]	[550,478,571]	0	hSpCas9	negative selection	1867764
41363887	41363910	17	+	26627737	HCT116	viability after 8 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.6068214347396217	[128]	[9,51,76]	-6	hSpCas9	negative selection	1867765
41363827	41363850	17	+	26627737	HCT116	viability after 9 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	1.2472670596353823	[171]	[103,112]	8	hSpCas9	negative selection	1950078
41363855	41363878	17	+	26627737	HCT116	viability after 9 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	1.037447083437496	[1666]	[792,1008]	7	hSpCas9	negative selection	1950079
41363887	41363910	17	+	26627737	HCT116	viability after 9 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-2.6069925062431247	[236]	[20,1]	-9	hSpCas9	negative selection	1950080
41363827	41363850	17	+	26627737	HCT116	viability after 12 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.15112020010574573	[252]	[142,112,100]	-1	hSpCas9	negative selection	2032393
41363855	41363878	17	+	26627737	HCT116	viability after 12 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	-0.2623943997809124	[927]	[494,447,269]	-3	hSpCas9	negative selection	2032394
41363887	41363910	17	+	26627737	HCT116	viability after 12 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.48327317818977056	[128]	[26,32,86]	-5	hSpCas9	negative selection	2032395
41363827	41363850	17	+	26627737	HCT116	viability after 15 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.3161316242296026	[252]	[204,191,148]	3	hSpCas9	negative selection	2114708
41363855	41363878	17	+	26627737	HCT116	viability after 15 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	-0.12618755813843063	[927]	[663,556,267]	-1	hSpCas9	negative selection	2114709
41363887	41363910	17	+	26627737	HCT116	viability after 15 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.7881150951517022	[128]	[32,9,83]	-7	hSpCas9	negative selection	2114710
41363827	41363850	17	+	26627737	HCT116	viability after 18 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.15321968865675567	[252]	[108,92,129]	-1	hSpCas9	negative selection	2197023
41363855	41363878	17	+	26627737	HCT116	viability after 18 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.21180085854028063	[927]	[507,607,432]	1	hSpCas9	negative selection	2197024
41363887	41363910	17	+	26627737	HCT116	viability after 18 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.7160410372872383	[128]	[55,3,56]	-6	hSpCas9	negative selection	2197025
41369891	41369914	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	AATGGAAAAATCAGCAAAGGAGG	KRT33B	ENSG00000131738	0.21216840110259316	[187,69]	[55,6]	1	dCas9-VP64	positive selection	2430002
41369945	41369968	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCAGAGTAAAACATTTAATGAGG	KRT33B	ENSG00000131738	0.40742676449946424	[16,143]	[7,39]	1	dCas9-VP64	positive selection	2430003
41369924	41369947	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGTATAGGACTCAGGTGAAGTGG	KRT33B	ENSG00000131738	0.4174888840775618	[76,44]	[5,29]	1	dCas9-VP64	positive selection	2430004
41382483	41382506	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	ACTAGCACCCAGGAAGAGCCTGG	KRT33B	ENSG00000131738	1.5217017441798781	[27,22]	[22,7]	5	dCas9-VP64	positive selection	2452751
41382549	41382572	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAATCATCACAGCCCCAAAAGG	KRT33B	ENSG00000131738	1.276765060620407	[238,92]	[31,147]	5	dCas9-VP64	positive selection	2452752
41382513	41382536	17	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAATCAGAGTTTCATCAGATGG	KRT33B	ENSG00000131738	-0.7278778602183453	[79,63]	[4,13]	-4	dCas9-VP64	positive selection	2452753
41369891	41369914	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	AATGGAAAAATCAGCAAAGGAGG	KRT33B	ENSG00000131738	-0.34055740665934864	[142,79]	[29,26]	-3	dCas9-VP64	positive selection	2525257
41369945	41369968	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCAGAGTAAAACATTTAATGAGG	KRT33B	ENSG00000131738	0.6630886734390938	[122,91]	[28,79]	5	dCas9-VP64	positive selection	2525258
41369924	41369947	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGTATAGGACTCAGGTGAAGTGG	KRT33B	ENSG00000131738	-0.05545260025844645	[79,96]	[36,18]	0	dCas9-VP64	positive selection	2525259
41382483	41382506	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	ACTAGCACCCAGGAAGAGCCTGG	KRT33B	ENSG00000131738	3.9311556638432483	[56,241]	[1496,32]	9	dCas9-VP64	positive selection	2548006
41382549	41382572	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAATCATCACAGCCCCAAAAGG	KRT33B	ENSG00000131738	1.3455173211365854	[94,117]	[59,114]	7	dCas9-VP64	positive selection	2548007
41382513	41382536	17	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAATCAGAGTTTCATCAGATGG	KRT33B	ENSG00000131738	-0.18704372457736945	[79,149]	[29,34]	-2	dCas9-VP64	positive selection	2548008
41369651	41369674	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACGGCTACACCCTGCCCGGGG	KRT33B	ENSG00000131738	-0.21214900278085702	[2,2]	[0,2]	-3	hSpCas9	positive selection	2998193
41366616	41366639	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-0.4685467380546073	[3,3]	[3,0]	-6	hSpCas9	positive selection	2998194
41366554	41366577	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.024411871939032936	[2,3]	[3,1]	0	hSpCas9	positive selection	2998195
41369619	41369642	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.26961274972052174	[4,3]	[4,4]	6	hSpCas9	positive selection	2998196
41369651	41369674	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACGGCTACACCCTGCCCGGGG	KRT33B	ENSG00000131738	0.3950351464634962	[2,2]	[3,1]	7	hSpCas9	positive selection	3066051
41366616	41366639	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.6926528163099773	[3,3]	[4,3]	9	hSpCas9	positive selection	3066052
41366554	41366577	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.01035048549506834	[2,2]	[2,1]	0	hSpCas9	positive selection	3066053
41369619	41369642	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.13683271051887935	[4,4]	[5,2]	2	hSpCas9	positive selection	3066054
41366616	41366639		-	24336571	A375	resistance to PLX after 7 days	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-0.49494690269575875	[7,12]	[5,7]	-9	hSpCas9	positive selection	3123772
41367916	41367939		+	24336571	A375	resistance to PLX after 7 days	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.09237038738631664	[1,2]	[2,2]	3	hSpCas9	positive selection	3123773
41367943	41367966		+	24336571	A375	resistance to PLX after 7 days	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.2067514439670648	[2,3]	[2,2]	-6	hSpCas9	positive selection	3123774
41366616	41366639		-	24336571	A375	resistance to PLX after 14 days	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-0.371488092666657	[5,14]	[4,1]	-4	hSpCas9	positive selection	3181565
41367916	41367939		+	24336571	A375	resistance to PLX after 14 days	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.8258025905264541	[1,2]	[1,1]	7	hSpCas9	positive selection	3181566
41367943	41367966		+	24336571	A375	resistance to PLX after 14 days	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.5802057641796468	[2,1]	[1,1]	5	hSpCas9	positive selection	3181567
41366616	41366639		-	24336571	A375	viability after 7 days	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.07292168848661112	[9]	[7,12]	1	hSpCas9	negative selection	3239358
41367916	41367939		+	24336571	A375	viability after 7 days	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.3768161407844768	[1]	[1,2]	6	hSpCas9	negative selection	3239359
41367943	41367966		+	24336571	A375	viability after 7 days	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.6695286207200499	[1]	[2,3]	8	hSpCas9	negative selection	3239360
41366616	41366639		-	24336571	A375	viability after 14 days	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.16494581713601214	[9]	[5,14]	2	hSpCas9	negative selection	3297151
41367916	41367939		+	24336571	A375	viability after 14 days	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.35180669878754234	[1]	[1,2]	4	hSpCas9	negative selection	3297152
41367943	41367966		+	24336571	A375	viability after 14 days	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.37304411596333553	[1]	[2,1]	5	hSpCas9	negative selection	3297153
41365204	41365227	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	1.4891418866689086	[217,217]	[3,3]	6	hSpCas9	positive selection	3376300
41365437	41365460	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.009398698002249677	[151,151]	[0,0]	0	hSpCas9	positive selection	3376301
41366502	41366525	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	1.6468286186175414	[341,341]	[6,6]	6	hSpCas9	positive selection	3376302
41369651	41369674	17	-	26780180	HT29	viability (Avana library 4 designs)	CCACGGCTACACCCTGCCCGGGG	KRT33B	ENSG00000131738	2.78622827969183	[]	[]	8	hSpCas9	negative selection	3435645
41366616	41366639	17	-	26780180	HT29	viability (Avana library 4 designs)	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.573350104863996	[]	[]	2	hSpCas9	negative selection	3435646
41366553	41366576	17	+	26780180	HT29	viability (Avana library 4 designs)	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.602376446784386	[]	[]	2	hSpCas9	negative selection	3435647
41369618	41369641	17	+	26780180	HT29	viability (Avana library 4 designs)	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	-0.0672608610997077	[]	[]	-1	hSpCas9	negative selection	3435648
41366616	41366639	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	1.66981708650727	[]	[]	2	hSpCas9	negative selection	3523315
41369651	41369674	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACGGCTACACCCTGCCCGGGG	KRT33B	ENSG00000131738	1.93941544306008	[]	[]	3	hSpCas9	negative selection	3523316
41366553	41366576	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-4.26888721061231	[]	[]	-5	hSpCas9	negative selection	3523317
41369618	41369641	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	4.13168488285133	[]	[]	6	hSpCas9	negative selection	3523318
41366470	41366493	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	2.4540191516236	[]	[]	3	hSpCas9	negative selection	3523319
41369651	41369674	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCCCGGGCAGGGTGTAGCCGTGG	KRT33B	ENSG00000131738	4.10388695116656	[]	[]	6	hSpCas9	negative selection	3523320
41366616	41366639	17	-	26780180	A375	viability (Avana lentiGuide)	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-1.73801584517569	[]	[]	-3	hSpCas9	negative selection	3631974
41369651	41369674	17	-	26780180	A375	viability (Avana lentiGuide)	CCACGGCTACACCCTGCCCGGGG	KRT33B	ENSG00000131738	17.6017190467624	[]	[]	8	hSpCas9	negative selection	3631975
41366553	41366576	17	+	26780180	A375	viability (Avana lentiGuide)	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-2.5379955730974	[]	[]	-4	hSpCas9	negative selection	3631976
41369618	41369641	17	+	26780180	A375	viability (Avana lentiGuide)	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.0098364718171795	[]	[]	0	hSpCas9	negative selection	3631977
41366470	41366493	17	+	26780180	A375	viability (Avana lentiGuide)	CTGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	-4.06840158375241	[]	[]	-7	hSpCas9	negative selection	3631978
41369651	41369674	17	+	26780180	A375	viability (Avana lentiGuide)	CCCCGGGCAGGGTGTAGCCGTGG	KRT33B	ENSG00000131738	1.58250259996913	[]	[]	1	hSpCas9	negative selection	3631979
41366616	41366639	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-0.16093027830562898	[5]	[5,3]	-3	hSpCas9	positive selection	3740633
41369651	41369674	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACGGCTACACCCTGCCCGGGG	KRT33B	ENSG00000131738	-0.09218807317345329	[3]	[3,2]	-1	hSpCas9	positive selection	3740634
41366553	41366576	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.6674068022423194	[4]	[3,1]	-7	hSpCas9	positive selection	3740635
41369618	41369641	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.1655882358527499	[5]	[6,5]	4	hSpCas9	positive selection	3740636
41366470	41366493	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.19053182962074666	[6]	[7,6]	5	hSpCas9	positive selection	3740637
41369651	41369674	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCCCGGGCAGGGTGTAGCCGTGG	KRT33B	ENSG00000131738	0.02839209580471702	[3]	[3,3]	0	hSpCas9	positive selection	3740638
41366616	41366639	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.27361906147059917	[5]	[5,5]	7	hSpCas9	positive selection	3849240
41369651	41369674	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACGGCTACACCCTGCCCGGGG	KRT33B	ENSG00000131738	-0.515338862742408	[4]	[3,1]	-6	hSpCas9	positive selection	3849241
41366553	41366576	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.7960258263666385	[5]	[2,1]	-7	hSpCas9	positive selection	3849242
41369618	41369641	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.21081580710962677	[5]	[6,5]	5	hSpCas9	positive selection	3849243
41366470	41366493	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.30830978432671746	[7]	[7,7]	8	hSpCas9	positive selection	3849244
41369651	41369674	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCCCGGGCAGGGTGTAGCCGTGG	KRT33B	ENSG00000131738	0.09072017970874219	[4]	[2,5]	2	hSpCas9	positive selection	3849245
41365525	41365548	17	-	26780180	A375	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	1.04014108058265	[]	[]	5	hSpCas9	negative selection	3955322
41365437	41365460	17	+	26780180	A375	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	1.18664904366344	[]	[]	6	hSpCas9	negative selection	3955323
41366502	41366525	17	+	26780180	A375	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	1.04714961378423	[]	[]	5	hSpCas9	negative selection	3955324
41365204	41365227	17	-	26780180	A375	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	1.97950143262562	[]	[]	9	hSpCas9	negative selection	3955325
41366553	41366576	17	+	26780180	A375	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	1.21242411202916	[]	[]	6	hSpCas9	negative selection	3955326
41367943	41367966	17	+	26780180	A375	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.827566614329989	[]	[]	3	hSpCas9	negative selection	3955327
41365525	41365548	17	-	26780180	HT29	viability (GeCKOv2 library)	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.830703385529447	[]	[]	3	hSpCas9	negative selection	4063288
41365437	41365460	17	+	26780180	HT29	viability (GeCKOv2 library)	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	2.13842710828251	[]	[]	9	hSpCas9	negative selection	4063289
41366502	41366525	17	+	26780180	HT29	viability (GeCKOv2 library)	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.348005529104518	[]	[]	1	hSpCas9	negative selection	4063290
41365204	41365227	17	-	26780180	HT29	viability (GeCKOv2 library)	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	1.57099219392645	[]	[]	8	hSpCas9	negative selection	4063291
41366553	41366576	17	+	26780180	HT29	viability (GeCKOv2 library)	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	1.67311802786731	[]	[]	8	hSpCas9	negative selection	4063292
41367943	41367966	17	+	26780180	HT29	viability (GeCKOv2 library)	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	1.23522218037079	[]	[]	6	hSpCas9	negative selection	4063293
41366616	41366639	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-0.14720571191092002	[2]	[1,1]	-3	hSpCas9	positive selection	4147738
41367916	41367939	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	-0.6249303623425897	[3]	[2,0]	-9	hSpCas9	positive selection	4147739
41367943	41367966	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.5360438083750888	[3]	[1,0]	-8	hSpCas9	positive selection	4147740
41366616	41366639	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.7882432222117582	[3]	[2,0,1,3]	5	hSpCas9	positive selection	4211760
41367916	41367939	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	-0.27265617791076713	[4]	[1,3,0,0]	-4	hSpCas9	positive selection	4211761
41367943	41367966	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.597173454572944	[4]	[1,3,1,3]	4	hSpCas9	positive selection	4211762
41367943	41367966	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.09303325104090268	[3]	[3,2]	2	hSpCas9	positive selection	4279158
41365525	41365548	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.39889851011747485	[4]	[4,4]	7	hSpCas9	positive selection	4279159
41366553	41366576	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.5869685634176973	[2]	[0,0]	-8	hSpCas9	positive selection	4279160
41367961	41367984	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.3792587017720487	[2]	[2,0]	-7	hSpCas9	positive selection	4343411
41365204	41365227	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	0.34947260645116285	[3]	[1,5]	7	hSpCas9	positive selection	4343413
41365437	41365460	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.32209360198096165	[2]	[2,2]	6	hSpCas9	positive selection	4343414
41366502	41366525	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.09999493552456495	[3]	[3,2]	2	hSpCas9	positive selection	4343415
41366471	41366493	17	+	27760321	OCIAML3	viability	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.16304269305621888	[647,605]	[511,597]	2	hSpCas9	negative selection	4413142
41367930	41367952	17	-	27760321	OCIAML3	viability	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.5639787759849428	[539,476]	[271,263]	-5	hSpCas9	negative selection	4413143
41369472	41369494	17	+	27760321	OCIAML3	viability	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	0.17760954496023218	[1121,979]	[838,1042]	2	hSpCas9	negative selection	4413144
41366471	41366493	17	+	27760321	OCIAML2	viability	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.31235935922152136	[647,605]	[542,744]	4	hSpCas9	negative selection	4496605
41367930	41367952	17	-	27760321	OCIAML2	viability	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.3482427554980928	[539,476]	[303,346]	-4	hSpCas9	negative selection	4496606
41369472	41369494	17	+	27760321	OCIAML2	viability	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.8322634062471627	[1121,979]	[390,588]	-7	hSpCas9	negative selection	4496607
41366471	41366493	17	+	27760321	MV411	viability	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	-0.027524509942553843	[647,605]	[352,485]	0	hSpCas9	negative selection	4580068
41367930	41367952	17	-	27760321	MV411	viability	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-1.1249429891875455	[539,476]	[133,182]	-6	hSpCas9	negative selection	4580069
41369472	41369494	17	+	27760321	MV411	viability	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.7575751331478571	[1121,979]	[292,583]	-5	hSpCas9	negative selection	4580070
41366471	41366493	17	+	27760321	HL60	viability	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.1097093412716712	[647,605]	[517,589]	1	hSpCas9	negative selection	4663531
41367930	41367952	17	-	27760321	HL60	viability	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.3831726544729438	[539,476]	[248,390]	-4	hSpCas9	negative selection	4663532
41369472	41369494	17	+	27760321	HL60	viability	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	0.27476114162056864	[1121,979]	[1178,884]	3	hSpCas9	negative selection	4663533
41366471	41366493	17	+	27760321	HT1080	viability	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.6965301754759514	[605,472]	[301,398]	4	hSpCas9	negative selection	4746994
41367930	41367952	17	-	27760321	HT1080	viability	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	1.1138262486914075	[476,371]	[27,735]	6	hSpCas9	negative selection	4746995
41369472	41369494	17	+	27760321	HT1080	viability	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-1.2659899324459662	[979,764]	[102,189]	-5	hSpCas9	negative selection	4746996
41366471	41366493	17	+	27760321	HT29	viability after 7 days	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.25119644407029307	[605,472]	[750,732,975]	4	hSpCas9	negative selection	4830457
41367930	41367952	17	-	27760321	HT29	viability after 7 days	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.1336285929338884	[476,371]	[523,489,481]	-2	hSpCas9	negative selection	4830458
41369472	41369494	17	+	27760321	HT29	viability after 7 days	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	0.2381891571368675	[979,764]	[1558,1111,1329]	3	hSpCas9	negative selection	4830459
41366471	41366493	17	+	27760321	HT29	viability after 25 days	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	-0.17283601200936233	[605,472]	[320,391,986]	-2	hSpCas9	negative selection	4913920
41367930	41367952	17	-	27760321	HT29	viability after 25 days	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.1197106535282359	[476,371]	[403,442,499]	-1	hSpCas9	negative selection	4913921
41369472	41369494	17	+	27760321	HT29	viability after 25 days	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.3549817845687748	[979,764]	[825,623,896]	-4	hSpCas9	negative selection	4913922
41366471	41366493	17	+	27760321	HT29	viability after 22 days	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.035906361460017355	[605,472]	[597,610,710]	0	hSpCas9	negative selection	4997383
41367930	41367952	17	-	27760321	HT29	viability after 22 days	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.4616816265137387	[476,371]	[248,453,368]	-4	hSpCas9	negative selection	4997384
41369472	41369494	17	+	27760321	HT29	viability after 22 days	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.014746835869300146	[979,764]	[1075,822,1094]	0	hSpCas9	negative selection	4997385
41366471	41366493	17	+	27760321	HT29	viability after 19 days	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	-0.20863595820032033	[605,472]	[460,308,812]	-2	hSpCas9	negative selection	5080846
41367930	41367952	17	-	27760321	HT29	viability after 19 days	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.7785999005576941	[476,371]	[373,165,316]	-6	hSpCas9	negative selection	5080847
41369472	41369494	17	+	27760321	HT29	viability after 19 days	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.037086853344649784	[979,764]	[1097,963,871]	0	hSpCas9	negative selection	5080848
41366471	41366493	17	+	27760321	HT29	viability after 16 days	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	-0.1517778015259848	[605,472]	[352,462,797]	-2	hSpCas9	negative selection	5164309
41367930	41367952	17	-	27760321	HT29	viability after 16 days	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.8145749937824752	[476,371]	[193,263,344]	-6	hSpCas9	negative selection	5164310
41369472	41369494	17	+	27760321	HT29	viability after 16 days	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.21803385295278677	[979,764]	[1099,656,789]	-2	hSpCas9	negative selection	5164311
41366471	41366493	17	+	27760321	HT29	viability after 13 days	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.26625748362254864	[605,472]	[925,686,650]	3	hSpCas9	negative selection	5247772
41367930	41367952	17	-	27760321	HT29	viability after 13 days	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.3867387621303947	[476,371]	[235,462,427]	-4	hSpCas9	negative selection	5247773
41369472	41369494	17	+	27760321	HT29	viability after 13 days	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.18364411893750532	[979,764]	[1201,770,710]	-2	hSpCas9	negative selection	5247774
41366471	41366493	17	+	27760321	HT29	viability after 10 days	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	0.15887749682284225	[605,472]	[699,916,645]	2	hSpCas9	negative selection	5331235
41367930	41367952	17	-	27760321	HT29	viability after 10 days	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-0.13546693991823208	[476,371]	[273,507,661]	-2	hSpCas9	negative selection	5331236
41369472	41369494	17	+	27760321	HT29	viability after 10 days	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.30682129961373417	[979,764]	[967,843,829]	-4	hSpCas9	negative selection	5331237
41366471	41366493	17	+	27760321	MOLM13	viability	TGCTCATGGTTCTGCTTGAGGG	KRT33B	ENSG00000131738	-0.26419128075264725	[647,605]	[385,216]	-2	hSpCas9	negative selection	5414698
41367930	41367952	17	-	27760321	MOLM13	viability	CAGATCGACAATGCCAAGCTGG	KRT33B	ENSG00000131738	-1.6476203093479216	[539,476]	[85,95]	-7	hSpCas9	negative selection	5414699
41369472	41369494	17	+	27760321	MOLM13	viability	CTGAGACCGCTCCCGGATGAGG	KRT33B	ENSG00000131738	-0.8565862562255939	[1121,979]	[289,357]	-5	hSpCas9	negative selection	5414700
41369754	41369777	17	+	27661255	K562	viability	GCAGGGAGGCAGTGGAGCTCTGG	KRT33B	ENSG00000131738	0.24792811820798952	[714,636]	[634,648]	8	dCas9-KRAB	negative selection	5489286
41382522	41382545	17	+	27661255	K562	viability	GTTTCATCAGATGGCTTCATAGG	KRT33B	ENSG00000131738	-0.011209715097105999	[1615,1713]	[1462,1194]	0	dCas9-KRAB	negative selection	5489288
41367943	41367966	17	+	27260156	BXPC3	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.4795528133304323	[549]	[696,769,928,823]	8	hSpCas9	negative selection	5551618
41365525	41365548	17	-	27260156	BXPC3	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.23243825881722158	[1324]	[1356,1529,1889,1780]	5	hSpCas9	negative selection	5551619
41366553	41366576	17	+	27260156	BXPC3	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.06938190161293989	[274]	[211,294,290,305]	-2	hSpCas9	negative selection	5551620
41367961	41367984	17	-	27260156	BXPC3	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.24536616503494235	[343]	[286,296,335,292]	-5	hSpCas9	negative selection	5615871
41365204	41365227	17	-	27260156	BXPC3	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.25027215590018465	[704]	[451,552,666,854]	-5	hSpCas9	negative selection	5615873
41365437	41365460	17	+	27260156	BXPC3	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.006504641585685422	[288]	[312,337,318,229]	0	hSpCas9	negative selection	5615874
41366502	41366525	17	+	27260156	BXPC3	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.3573260409347955	[667]	[890,769,909,1025]	7	hSpCas9	negative selection	5615875
41367943	41367966	17	+	27260156	A673	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.06702971224911067	[549]	[655,598,581,690]	-2	hSpCas9	negative selection	5672869
41365525	41365548	17	-	27260156	A673	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.30856555333428837	[1324]	[2155,1820,1984,1938]	7	hSpCas9	negative selection	5672870
41366553	41366576	17	+	27260156	A673	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.14671962824668194	[274]	[403,319,347,396]	3	hSpCas9	negative selection	5672871
41367961	41367984	17	-	27260156	A673	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	0.10959482692472006	[343]	[448,447,396,490]	2	hSpCas9	negative selection	5737122
41365204	41365227	17	-	27260156	A673	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.31108470619581413	[704]	[696,623,737,670]	-6	hSpCas9	negative selection	5737124
41365437	41365460	17	+	27260156	A673	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.2171071007432469	[288]	[497,352,358,415]	5	hSpCas9	negative selection	5737125
41366502	41366525	17	+	27260156	A673	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.3346564513259015	[667]	[1142,963,1029,917]	7	hSpCas9	negative selection	5737126
41367943	41367966	17	+	27260156	A375	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.13907371121154613	[549]	[545,816,678,788]	2	hSpCas9	negative selection	5794120
41365525	41365548	17	-	27260156	A375	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.06252760967302162	[1324]	[1801,1776,1582,1351]	0	hSpCas9	negative selection	5794121
41366553	41366576	17	+	27260156	A375	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.033225014862788615	[274]	[329,451,195,349]	0	hSpCas9	negative selection	5794122
41367961	41367984	17	-	27260156	A375	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.3514514225327937	[343]	[325,379,305,261]	-5	hSpCas9	negative selection	5858373
41365204	41365227	17	-	27260156	A375	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.3958050377020347	[704]	[565,735,699,525]	-5	hSpCas9	negative selection	5858375
41365437	41365460	17	+	27260156	A375	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.18133747405163902	[288]	[335,502,481,241]	2	hSpCas9	negative selection	5858376
41366502	41366525	17	+	27260156	A375	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.7652763757171963	[667]	[1253,1937,1337,904]	9	hSpCas9	negative selection	5858377
41367943	41367966	17	+	27260156	COLO741	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.05623039380519848	[549]	[806,760,635]	1	hSpCas9	negative selection	5915371
41365525	41365548	17	-	27260156	COLO741	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.384019471344238	[1324]	[2131,2449,2046]	7	hSpCas9	negative selection	5915372
41366553	41366576	17	+	27260156	COLO741	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.1673975000950063	[274]	[386,326,235]	-4	hSpCas9	negative selection	5915373
41367961	41367984	17	-	27260156	COLO741	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	0.013993919566582802	[343]	[391,501,432]	0	hSpCas9	negative selection	5979624
41365204	41365227	17	-	27260156	COLO741	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.49816304799200023	[704]	[639,786,495]	-8	hSpCas9	negative selection	5979626
41365437	41365460	17	+	27260156	COLO741	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	-0.021038612964714987	[288]	[455,312,331]	0	hSpCas9	negative selection	5979627
41366502	41366525	17	+	27260156	COLO741	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.45421460820045556	[667]	[1026,1232,1228]	8	hSpCas9	negative selection	5979628
41367943	41367966	17	+	27260156	CAL120	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.2656102960013567	[549]	[609,653,451]	-4	hSpCas9	negative selection	6036622
41365525	41365548	17	-	27260156	CAL120	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.238631209434794	[1324]	[2397,1813,1695]	3	hSpCas9	negative selection	6036623
41366553	41366576	17	+	27260156	CAL120	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.07522178878117736	[274]	[547,277,284]	1	hSpCas9	negative selection	6036624
41367961	41367984	17	-	27260156	CAL120	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.9099117290809033	[343]	[182,285,207]	-8	hSpCas9	negative selection	6100875
41365204	41365227	17	-	27260156	CAL120	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.5150849161161511	[704]	[634,618,590]	-6	hSpCas9	negative selection	6100877
41365437	41365460	17	+	27260156	CAL120	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.39735008281763157	[288]	[431,423,556]	6	hSpCas9	negative selection	6100878
41366502	41366525	17	+	27260156	CAL120	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.37596215772819397	[667]	[1157,1254,838]	5	hSpCas9	negative selection	6100879
41367943	41367966	17	+	27260156	CADOES1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.1847012811031051	[549]	[607,741,340,636]	3	hSpCas9	negative selection	6157873
41365525	41365548	17	-	27260156	CADOES1	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.24566156820304963	[1324]	[1465,1381,1513,1482]	4	hSpCas9	negative selection	6157874
41366553	41366576	17	+	27260156	CADOES1	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.03829609776409881	[274]	[206,182,336,269]	0	hSpCas9	negative selection	6157875
41367961	41367984	17	-	27260156	CADOES1	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.2128280627449789	[343]	[257,255,319,269]	-4	hSpCas9	negative selection	6222126
41365204	41365227	17	-	27260156	CADOES1	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.43782367860044713	[704]	[518,394,485,537]	-6	hSpCas9	negative selection	6222128
41365437	41365460	17	+	27260156	CADOES1	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.1757264521656412	[288]	[311,337,221,343]	3	hSpCas9	negative selection	6222129
41366502	41366525	17	+	27260156	CADOES1	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.520369650484225	[667]	[955,648,831,1135]	8	hSpCas9	negative selection	6222130
41367943	41367966	17	+	27260156	EWS502	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.10621168822750784	[549]	[605,522,416,612]	-2	hSpCas9	negative selection	6279124
41365525	41365548	17	-	27260156	EWS502	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.32422197044676127	[1324]	[1542,1703,2026,1780]	5	hSpCas9	negative selection	6279125
41366553	41366576	17	+	27260156	EWS502	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.3862665948781555	[274]	[161,256,222,256]	-6	hSpCas9	negative selection	6279126
41367961	41367984	17	-	27260156	EWS502	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	0.07850089978152608	[343]	[315,233,462,551]	1	hSpCas9	negative selection	6343377
41365204	41365227	17	-	27260156	EWS502	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.4624986714489596	[704]	[601,455,578,523]	-7	hSpCas9	negative selection	6343379
41365437	41365460	17	+	27260156	EWS502	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	-0.08034278985541066	[288]	[324,245,333,246]	-1	hSpCas9	negative selection	6343380
41366502	41366525	17	+	27260156	EWS502	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.7434449955312741	[667]	[1188,1211,1262,1059]	9	hSpCas9	negative selection	6343381
41367943	41367966	17	+	27260156	EW8	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.063582780827277	[549]	[456,483,405,523]	1	hSpCas9	negative selection	6400375
41365525	41365548	17	-	27260156	EW8	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.28738966478383254	[1324]	[1626,1334,1130,1210]	5	hSpCas9	negative selection	6400376
41366553	41366576	17	+	27260156	EW8	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.24820041507455903	[274]	[330,126,143,170]	-5	hSpCas9	negative selection	6400377
41367961	41367984	17	-	27260156	EW8	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.2786687256570112	[343]	[242,266,165,254]	-5	hSpCas9	negative selection	6464628
41365204	41365227	17	-	27260156	EW8	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.39851842375334434	[704]	[432,451,334,528]	-6	hSpCas9	negative selection	6464630
41365437	41365460	17	+	27260156	EW8	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.03442715470621727	[288]	[374,196,135,282]	0	hSpCas9	negative selection	6464631
41366502	41366525	17	+	27260156	EW8	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.5029148798800691	[667]	[883,760,571,894]	8	hSpCas9	negative selection	6464632
41367943	41367966	17	+	27260156	CORL105	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.29031721594024906	[549]	[818,778,751,794]	5	hSpCas9	negative selection	6521626
41365525	41365548	17	-	27260156	CORL105	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.3689122649410679	[1324]	[1943,1796,2204,2098]	7	hSpCas9	negative selection	6521627
41366553	41366576	17	+	27260156	CORL105	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.002927963144249923	[274]	[289,360,319,311]	0	hSpCas9	negative selection	6521628
41367961	41367984	17	-	27260156	CORL105	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.3326619952629304	[343]	[297,250,336,395]	-6	hSpCas9	negative selection	6585879
41365204	41365227	17	-	27260156	CORL105	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.25318339371994497	[704]	[694,645,907,555]	-5	hSpCas9	negative selection	6585881
41365437	41365460	17	+	27260156	CORL105	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.10895646341532983	[288]	[349,265,387,459]	2	hSpCas9	negative selection	6585882
41366502	41366525	17	+	27260156	CORL105	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.5170351418445103	[667]	[1274,929,1288,1017]	8	hSpCas9	negative selection	6585883
41367943	41367966	17	+	27260156	HS294T	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.2110926829616503	[549]	[209,155,185,179]	-3	hSpCas9	negative selection	6642877
41365525	41365548	17	-	27260156	HS294T	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.9074047291236667	[1324]	[937,1039,810,1068]	9	hSpCas9	negative selection	6642878
41366553	41366576	17	+	27260156	HS294T	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.42478643386518716	[274]	[128,166,121,154]	6	hSpCas9	negative selection	6642879
41367961	41367984	17	-	27260156	HS294T	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.4729059133548972	[343]	[88,67,114,115]	-6	hSpCas9	negative selection	6707130
41365204	41365227	17	-	27260156	HS294T	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.10009230935527474	[704]	[149,298,231,361]	-1	hSpCas9	negative selection	6707132
41365437	41365460	17	+	27260156	HS294T	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.741542332295284	[288]	[92,182,112,402]	8	hSpCas9	negative selection	6707133
41366502	41366525	17	+	27260156	HS294T	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.3832660437513603	[667]	[332,334,370,301]	5	hSpCas9	negative selection	6707134
41367943	41367966	17	+	27260156	HCC44	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.25561715759247416	[549]	[568,552,533,428]	-4	hSpCas9	negative selection	6764128
41365525	41365548	17	-	27260156	HCC44	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.2231358408535704	[1324]	[2085,1282,2125,1652]	3	hSpCas9	negative selection	6764129
41366553	41366576	17	+	27260156	HCC44	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.07246222928646462	[274]	[302,255,451,205]	-1	hSpCas9	negative selection	6764130
41367961	41367984	17	-	27260156	HCC44	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.13820227047155453	[343]	[261,394,514,255]	-2	hSpCas9	negative selection	6828381
41365204	41365227	17	-	27260156	HCC44	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.2747831516535514	[704]	[923,696,638,394]	-4	hSpCas9	negative selection	6828383
41365437	41365460	17	+	27260156	HCC44	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.4856435795864492	[288]	[482,517,388,419]	7	hSpCas9	negative selection	6828384
41366502	41366525	17	+	27260156	HCC44	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.39353438722347966	[667]	[1339,568,1415,807]	6	hSpCas9	negative selection	6828385
41367943	41367966	17	+	27260156	G402	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.38139245215873485	[549]	[937,521,721,1279]	5	hSpCas9	negative selection	6885379
41365525	41365548	17	-	27260156	G402	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.28008508583936664	[1324]	[1681,2751,1466,1949]	3	hSpCas9	negative selection	6885380
41366553	41366576	17	+	27260156	G402	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.17863191105536624	[274]	[628,404,265,260]	2	hSpCas9	negative selection	6885381
41367961	41367984	17	-	27260156	G402	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.5256982745080147	[343]	[184,623,278,90]	-6	hSpCas9	negative selection	6949632
41365204	41365227	17	-	27260156	G402	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.1445527743337685	[704]	[709,698,538,1129]	-2	hSpCas9	negative selection	6949634
41365437	41365460	17	+	27260156	G402	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.10441975649671775	[288]	[450,457,306,316]	1	hSpCas9	negative selection	6949635
41366502	41366525	17	+	27260156	G402	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.6677854960234881	[667]	[1275,1562,1066,1281]	8	hSpCas9	negative selection	6949636
41367943	41367966	17	+	27260156	L33	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.2560301406706794	[549]	[754,298,427,460]	5	hSpCas9	negative selection	7006630
41365525	41365548	17	-	27260156	L33	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.23674269707838125	[1324]	[1528,634,999,1575]	5	hSpCas9	negative selection	7006631
41366553	41366576	17	+	27260156	L33	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.7306493355676827	[274]	[501,177,218,537]	9	hSpCas9	negative selection	7006632
41367961	41367984	17	-	27260156	L33	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.08366657571972402	[343]	[307,165,192,278]	-2	hSpCas9	negative selection	7070883
41365204	41365227	17	-	27260156	L33	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.5272207309619856	[704]	[446,209,344,449]	-8	hSpCas9	negative selection	7070885
41365437	41365460	17	+	27260156	L33	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	-0.046333097314788074	[288]	[285,87,196,304]	-1	hSpCas9	negative selection	7070886
41366502	41366525	17	+	27260156	L33	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.3323432566359258	[667]	[897,373,499,756]	7	hSpCas9	negative selection	7070887
41367943	41367966	17	+	27260156	K562	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.6174249594555687	[549]	[847,708,814,638]	7	hSpCas9	negative selection	7127881
41365525	41365548	17	-	27260156	K562	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.3531727107614795	[1324]	[1353,1457,2077,1139]	4	hSpCas9	negative selection	7127882
41366553	41366576	17	+	27260156	K562	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.3618363493042823	[274]	[178,271,203,115]	-4	hSpCas9	negative selection	7127883
41367961	41367984	17	-	27260156	K562	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.5503088110201346	[343]	[368,197,111,170]	-6	hSpCas9	negative selection	7192134
41365204	41365227	17	-	27260156	K562	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.4142931228207334	[704]	[358,257,271,913]	-5	hSpCas9	negative selection	7192136
41365437	41365460	17	+	27260156	K562	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.45213959422333483	[288]	[308,218,308,532]	6	hSpCas9	negative selection	7192137
41366502	41366525	17	+	27260156	K562	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.8456282232892132	[667]	[1214,1233,1048,809]	9	hSpCas9	negative selection	7192138
41367943	41367966	17	+	27260156	HT29	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.1299044456716763	[549]	[546,862,620,445]	-3	hSpCas9	negative selection	7249132
41365525	41365548	17	-	27260156	HT29	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.1935721246606088	[1324]	[1907,1916,1914,1649]	4	hSpCas9	negative selection	7249133
41366553	41366576	17	+	27260156	HT29	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.1569168892134427	[274]	[236,387,248,322]	-3	hSpCas9	negative selection	7249134
41367961	41367984	17	-	27260156	HT29	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.5276293549645051	[343]	[334,233,334,256]	-7	hSpCas9	negative selection	7313385
41365204	41365227	17	-	27260156	HT29	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.6512949722537418	[704]	[574,628,670,338]	-8	hSpCas9	negative selection	7313387
41365437	41365460	17	+	27260156	HT29	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	-0.35163093044820115	[288]	[337,399,219,169]	-6	hSpCas9	negative selection	7313388
41366502	41366525	17	+	27260156	HT29	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.37403472359358925	[667]	[1346,1005,882,991]	7	hSpCas9	negative selection	7313389
41367943	41367966	17	+	27260156	MHHES1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.1310298642559912	[549]	[675,747,718,583]	2	hSpCas9	negative selection	7370383
41365525	41365548	17	-	27260156	MHHES1	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.23035665995943067	[1324]	[1871,2071,1801,1356]	4	hSpCas9	negative selection	7370384
41366553	41366576	17	+	27260156	MHHES1	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.25845339560227476	[274]	[386,433,485,212]	5	hSpCas9	negative selection	7370385
41367961	41367984	17	-	27260156	MHHES1	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.10313017475231578	[343]	[336,487,228,383]	-2	hSpCas9	negative selection	7434636
41365204	41365227	17	-	27260156	MHHES1	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.23706163630967542	[704]	[831,750,510,622]	-4	hSpCas9	negative selection	7434638
41365437	41365460	17	+	27260156	MHHES1	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.4173777205965938	[288]	[368,597,412,371]	7	hSpCas9	negative selection	7434639
41366502	41366525	17	+	27260156	MHHES1	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.3496072420823707	[667]	[1133,920,897,891]	6	hSpCas9	negative selection	7434640
41367943	41367966	17	+	27260156	MEWO	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.13365245297852368	[549]	[597,463,369]	-3	hSpCas9	negative selection	7491634
41365525	41365548	17	-	27260156	MEWO	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.3228876803933747	[1324]	[1585,1588,1482]	7	hSpCas9	negative selection	7491635
41366553	41366576	17	+	27260156	MEWO	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.2361118396088414	[274]	[316,245,348]	5	hSpCas9	negative selection	7491636
41367961	41367984	17	-	27260156	MEWO	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.11526238502895225	[343]	[325,274,295]	-3	hSpCas9	negative selection	7555887
41365204	41365227	17	-	27260156	MEWO	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.28284182606947017	[704]	[673,514,462]	-6	hSpCas9	negative selection	7555889
41365437	41365460	17	+	27260156	MEWO	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.2456657680531502	[288]	[347,310,307]	5	hSpCas9	negative selection	7555890
41366502	41366525	17	+	27260156	MEWO	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.4030452443763697	[667]	[934,823,740]	8	hSpCas9	negative selection	7555891
41367943	41367966	17	+	27260156	LNCAPCLONEFGC	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.06706348988337976	[549]	[482,401,615,608]	1	hSpCas9	negative selection	7612885
41365525	41365548	17	-	27260156	LNCAPCLONEFGC	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.1943435269717706	[1324]	[1437,1108,1678,1327]	3	hSpCas9	negative selection	7612886
41366553	41366576	17	+	27260156	LNCAPCLONEFGC	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.20419242898444456	[274]	[179,220,241,225]	-3	hSpCas9	negative selection	7612887
41367961	41367984	17	-	27260156	LNCAPCLONEFGC	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.13127102809765656	[343]	[319,262,320,239]	-2	hSpCas9	negative selection	7677138
41365204	41365227	17	-	27260156	LNCAPCLONEFGC	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.7442724948674275	[704]	[284,427,532,299]	-8	hSpCas9	negative selection	7677140
41365437	41365460	17	+	27260156	LNCAPCLONEFGC	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	-0.17059143075393046	[288]	[210,214,307,208]	-3	hSpCas9	negative selection	7677141
41366502	41366525	17	+	27260156	LNCAPCLONEFGC	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.4877379975993106	[667]	[717,698,1266,783]	7	hSpCas9	negative selection	7677142
41367943	41367966	17	+	27260156	PANC0327	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.6286857484056678	[549]	[915,862,819,421]	8	hSpCas9	negative selection	7734136
41365525	41365548	17	-	27260156	PANC0327	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.20160418331697127	[1324]	[1267,1307,1143,1691]	3	hSpCas9	negative selection	7734137
41366553	41366576	17	+	27260156	PANC0327	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.5291280376735182	[274]	[185,210,123,151]	-6	hSpCas9	negative selection	7734138
41367961	41367984	17	-	27260156	PANC0327	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.6674032257821796	[343]	[193,267,197,99]	-7	hSpCas9	negative selection	7798389
41365204	41365227	17	-	27260156	PANC0327	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.1725567805938658	[704]	[508,595,794,313]	-3	hSpCas9	negative selection	7798391
41365437	41365460	17	+	27260156	PANC0327	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.01083131730654363	[288]	[224,192,177,443]	0	hSpCas9	negative selection	7798392
41366502	41366525	17	+	27260156	PANC0327	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.0463565040401448	[667]	[711,609,429,706]	0	hSpCas9	negative selection	7798393
41367943	41367966	17	+	27260156	NCIH2009	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.6219131326517432	[549]	[1343,1048,1186]	8	hSpCas9	negative selection	7855387
41365525	41365548	17	-	27260156	NCIH2009	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.04090991449204506	[1324]	[2391,1549,1870]	0	hSpCas9	negative selection	7855388
41366553	41366576	17	+	27260156	NCIH2009	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.08941643480410377	[274]	[535,342,372]	1	hSpCas9	negative selection	7855389
41367961	41367984	17	-	27260156	NCIH2009	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.5194774397586628	[343]	[521,236,284]	-6	hSpCas9	negative selection	7919640
41365204	41365227	17	-	27260156	NCIH2009	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.7888317299383562	[704]	[550,549,604]	-7	hSpCas9	negative selection	7919642
41365437	41365460	17	+	27260156	NCIH2009	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.5488220914594291	[288]	[642,556,581]	7	hSpCas9	negative selection	7919643
41366502	41366525	17	+	27260156	NCIH2009	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.776567868560232	[667]	[2035,1547,1296]	9	hSpCas9	negative selection	7919644
41367943	41367966	17	+	27260156	NCIH1373	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.47378456113161616	[549]	[822,907,902,201]	4	hSpCas9	negative selection	7976638
41365525	41365548	17	-	27260156	NCIH1373	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.3439653111238343	[1324]	[1916,1585,1512,683]	3	hSpCas9	negative selection	7976639
41366553	41366576	17	+	27260156	NCIH1373	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.23603096335702245	[274]	[342,235,411,124]	2	hSpCas9	negative selection	7976640
41367961	41367984	17	-	27260156	NCIH1373	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.49354792337704834	[343]	[299,407,153,57]	-5	hSpCas9	negative selection	8040891
41365204	41365227	17	-	27260156	NCIH1373	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	0.08668546762768026	[704]	[741,709,895,265]	0	hSpCas9	negative selection	8040893
41365437	41365460	17	+	27260156	NCIH1373	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.9655313418554134	[288]	[511,558,567,234]	8	hSpCas9	negative selection	8040894
41366502	41366525	17	+	27260156	NCIH1373	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	1.0231433858438066	[667]	[1436,1263,1078,623]	9	hSpCas9	negative selection	8040895
41367943	41367966	17	+	27260156	PATU8902	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.8652901982771678	[549]	[1241,1467,1110,1883]	8	hSpCas9	negative selection	8097889
41365525	41365548	17	-	27260156	PATU8902	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	-0.4308917480657821	[1324]	[1149,1930,1295,1075]	-4	hSpCas9	negative selection	8097890
41366553	41366576	17	+	27260156	PATU8902	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.4566168182489244	[274]	[44,181,387,499]	-4	hSpCas9	negative selection	8097891
41367961	41367984	17	-	27260156	PATU8902	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.3716597429939572	[343]	[341,561,118,541]	-4	hSpCas9	negative selection	8162142
41365204	41365227	17	-	27260156	PATU8902	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.5954020896501826	[704]	[450,272,107,2074]	-5	hSpCas9	negative selection	8162144
41365437	41365460	17	+	27260156	PATU8902	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.3391232938966034	[288]	[685,564,357,453]	3	hSpCas9	negative selection	8162145
41366502	41366525	17	+	27260156	PATU8902	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.9347915261219413	[667]	[2123,1501,1821,1614]	8	hSpCas9	negative selection	8162146
41367943	41367966	17	+	27260156	PANC1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.5017686877159374	[549]	[724,684,707,565]	7	hSpCas9	negative selection	8219140
41365525	41365548	17	-	27260156	PANC1	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.35650736401880057	[1324]	[1353,1750,1480,1305]	6	hSpCas9	negative selection	8219141
41366553	41366576	17	+	27260156	PANC1	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.5704951715507177	[274]	[162,141,165,158]	-7	hSpCas9	negative selection	8219142
41367961	41367984	17	-	27260156	PANC1	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.1183611806202598	[343]	[284,292,297,220]	-2	hSpCas9	negative selection	8283393
41365204	41365227	17	-	27260156	PANC1	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.3927943120388161	[704]	[446,715,507,253]	-6	hSpCas9	negative selection	8283395
41365437	41365460	17	+	27260156	PANC1	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	-0.04478411275123484	[288]	[205,342,243,194]	0	hSpCas9	negative selection	8283396
41366502	41366525	17	+	27260156	PANC1	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.5848859310304568	[667]	[777,856,943,851]	8	hSpCas9	negative selection	8283397
41367943	41367966	17	+	27260156	PANC0813	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.3647063667121979	[549]	[877,883,806,764]	6	hSpCas9	negative selection	8340391
41365525	41365548	17	-	27260156	PANC0813	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.2863870664137924	[1324]	[1581,1790,2115,2062]	4	hSpCas9	negative selection	8340392
41366553	41366576	17	+	27260156	PANC0813	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.06381102179785214	[274]	[452,317,298,292]	1	hSpCas9	negative selection	8340393
41367961	41367984	17	-	27260156	PANC0813	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.19482164450787198	[343]	[349,311,404,344]	-3	hSpCas9	negative selection	8404644
41365204	41365227	17	-	27260156	PANC0813	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.4607139033347326	[704]	[668,650,719,384]	-6	hSpCas9	negative selection	8404646
41365437	41365460	17	+	27260156	PANC0813	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.18032726185852987	[288]	[399,339,489,313]	3	hSpCas9	negative selection	8404647
41366502	41366525	17	+	27260156	PANC0813	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.45459769600972477	[667]	[891,1306,1230,864]	7	hSpCas9	negative selection	8404648
41367943	41367966	17	+	27260156	RDES	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.33198368152725743	[549]	[696,780,914,792]	5	hSpCas9	negative selection	8461642
41365525	41365548	17	-	27260156	RDES	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.14088466389107723	[1324]	[1430,1425,1886,2070]	2	hSpCas9	negative selection	8461643
41366553	41366576	17	+	27260156	RDES	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.2812075621798674	[274]	[248,176,396,218]	-5	hSpCas9	negative selection	8461644
41367961	41367984	17	-	27260156	RDES	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.5041248303966255	[343]	[283,311,240,259]	-7	hSpCas9	negative selection	8525895
41365204	41365227	17	-	27260156	RDES	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.3106080633397402	[704]	[469,588,869,733]	-5	hSpCas9	negative selection	8525897
41365437	41365460	17	+	27260156	RDES	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.19942988622043478	[288]	[371,267,400,505]	3	hSpCas9	negative selection	8525898
41366502	41366525	17	+	27260156	RDES	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.5906773483740468	[667]	[945,1023,1439,1268]	8	hSpCas9	negative selection	8525899
41367943	41367966	17	+	27260156	PC3	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.04344199334842594	[549]	[293,671,799,513]	-1	hSpCas9	negative selection	8582893
41365525	41365548	17	-	27260156	PC3	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.3797316915666047	[1324]	[885,1715,3228,1861]	7	hSpCas9	negative selection	8582894
41366553	41366576	17	+	27260156	PC3	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.19729526069243486	[274]	[138,389,630,267]	4	hSpCas9	negative selection	8582895
41367961	41367984	17	-	27260156	PC3	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.05937505858472203	[343]	[148,402,628,300]	-1	hSpCas9	negative selection	8647146
41365204	41365227	17	-	27260156	PC3	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.33062008987833724	[704]	[395,478,1045,517]	-6	hSpCas9	negative selection	8647148
41365437	41365460	17	+	27260156	PC3	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.17988289869909735	[288]	[185,324,534,374]	4	hSpCas9	negative selection	8647149
41366502	41366525	17	+	27260156	PC3	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.3254605418050833	[667]	[566,800,1350,851]	7	hSpCas9	negative selection	8647150
41367943	41367966	17	+	27260156	PATU8988T	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.2838737671459206	[549]	[876,623,623,444]	5	hSpCas9	negative selection	8704144
41365525	41365548	17	-	27260156	PATU8988T	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.15276078600065035	[1324]	[1470,1652,1064,1539]	2	hSpCas9	negative selection	8704145
41366553	41366576	17	+	27260156	PATU8988T	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.21334277936179658	[274]	[275,293,166,182]	-4	hSpCas9	negative selection	8704146
41367961	41367984	17	-	27260156	PATU8988T	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.783092125631063	[343]	[246,129,124,271]	-8	hSpCas9	negative selection	8768397
41365204	41365227	17	-	27260156	PATU8988T	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.7779768789957544	[704]	[505,317,430,319]	-8	hSpCas9	negative selection	8768399
41365437	41365460	17	+	27260156	PATU8988T	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.11549663732609461	[288]	[277,220,341,365]	2	hSpCas9	negative selection	8768400
41366502	41366525	17	+	27260156	PATU8988T	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.44583294790889383	[667]	[697,1004,686,1163]	7	hSpCas9	negative selection	8768401
41367943	41367966	17	+	27260156	T47D	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.13976138024877538	[549]	[650,565,541,568]	-3	hSpCas9	negative selection	8825395
41365525	41365548	17	-	27260156	T47D	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.11227228506841502	[1324]	[1624,1553,1827,1673]	2	hSpCas9	negative selection	8825396
41366553	41366576	17	+	27260156	T47D	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.174897940061845	[274]	[290,225,323,298]	-4	hSpCas9	negative selection	8825397
41367961	41367984	17	-	27260156	T47D	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.5152526448293705	[343]	[266,271,318,262]	-8	hSpCas9	negative selection	8889648
41365204	41365227	17	-	27260156	T47D	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.4672630495944323	[704]	[585,608,685,488]	-7	hSpCas9	negative selection	8889650
41365437	41365460	17	+	27260156	T47D	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	-0.13006198342665132	[288]	[309,263,303,357]	-3	hSpCas9	negative selection	8889651
41366502	41366525	17	+	27260156	T47D	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.31687711853034417	[667]	[1010,815,964,1102]	6	hSpCas9	negative selection	8889652
41367943	41367966	17	+	27260156	SU8686	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.19458034107205177	[549]	[595,580,628,707]	3	hSpCas9	negative selection	8946646
41365525	41365548	17	-	27260156	SU8686	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.00854011526951659	[1324]	[1216,1255,1304,1555]	0	hSpCas9	negative selection	8946647
41366553	41366576	17	+	27260156	SU8686	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.1045963694108597	[274]	[285,256,267,377]	1	hSpCas9	negative selection	8946648
41367961	41367984	17	-	27260156	SU8686	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.3316939834881578	[343]	[249,264,336,227]	-5	hSpCas9	negative selection	9010899
41365204	41365227	17	-	27260156	SU8686	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.6545394975838859	[704]	[402,391,511,485]	-7	hSpCas9	negative selection	9010901
41365437	41365460	17	+	27260156	SU8686	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.2667515329743146	[288]	[319,298,362,414]	4	hSpCas9	negative selection	9010902
41366502	41366525	17	+	27260156	SU8686	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.5931341946555082	[667]	[1036,826,1041,1121]	8	hSpCas9	negative selection	9010903
41367943	41367966	17	+	27260156	SKES1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.19114775344320845	[549]	[485,580,432,435]	-4	hSpCas9	negative selection	9067897
41365525	41365548	17	-	27260156	SKES1	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.36601559120635807	[1324]	[2044,2015,1504,1358]	7	hSpCas9	negative selection	9067898
41366553	41366576	17	+	27260156	SKES1	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.33379359048333085	[274]	[409,303,339,330]	7	hSpCas9	negative selection	9067899
41367961	41367984	17	-	27260156	SKES1	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.07308843434985968	[343]	[356,309,384,258]	-1	hSpCas9	negative selection	9132150
41365204	41365227	17	-	27260156	SKES1	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.2836041107091679	[704]	[721,479,609,508]	-6	hSpCas9	negative selection	9132152
41365437	41365460	17	+	27260156	SKES1	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.1504825681403038	[288]	[392,360,281,262]	3	hSpCas9	negative selection	9132153
41366502	41366525	17	+	27260156	SKES1	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.4702033626599713	[667]	[1138,1004,981,630]	8	hSpCas9	negative selection	9132154
41367943	41367966	17	+	27260156	TOV112D	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.6122381658332402	[549]	[654,538,1295,787]	9	hSpCas9	negative selection	9189148
41365525	41365548	17	-	27260156	TOV112D	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.21882098184690313	[1324]	[1564,2211,1016,1546]	4	hSpCas9	negative selection	9189149
41366553	41366576	17	+	27260156	TOV112D	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.010235731863053488	[274]	[228,520,212,189]	0	hSpCas9	negative selection	9189150
41367961	41367984	17	-	27260156	TOV112D	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.5714487867574911	[343]	[260,338,165,190]	-8	hSpCas9	negative selection	9253401
41365204	41365227	17	-	27260156	TOV112D	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.4421358094920149	[704]	[626,554,512,403]	-7	hSpCas9	negative selection	9253403
41365437	41365460	17	+	27260156	TOV112D	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.19524853295586775	[288]	[448,382,269,247]	4	hSpCas9	negative selection	9253404
41366502	41366525	17	+	27260156	TOV112D	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.2657230342238913	[667]	[899,893,714,738]	5	hSpCas9	negative selection	9253405
41367943	41367966	17	+	27260156	TC71	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.31893556811346396	[549]	[415,518,427,533]	-7	hSpCas9	negative selection	9310399
41365525	41365548	17	-	27260156	TC71	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.25412375658824105	[1324]	[1714,1764,1423,1891]	6	hSpCas9	negative selection	9310400
41366553	41366576	17	+	27260156	TC71	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	0.29166669268757905	[274]	[374,265,402,399]	7	hSpCas9	negative selection	9310401
41367961	41367984	17	-	27260156	TC71	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.05799298280057663	[343]	[177,460,379,403]	-1	hSpCas9	negative selection	9374652
41365204	41365227	17	-	27260156	TC71	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.520062728881785	[704]	[450,716,449,491]	-8	hSpCas9	negative selection	9374654
41365437	41365460	17	+	27260156	TC71	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.015355378177679846	[288]	[297,284,308,363]	0	hSpCas9	negative selection	9374655
41366502	41366525	17	+	27260156	TC71	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.434809284536256	[667]	[964,1029,885,994]	8	hSpCas9	negative selection	9374656
41367943	41367966	17	+	27260156	TC32	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.13258995290356698	[549]	[414,564,689,603]	2	hSpCas9	negative selection	9431650
41365525	41365548	17	-	27260156	TC32	viability	AACACCTTGCGCTGCCAGCTTGG	KRT33B	ENSG00000131738	0.27390707838040407	[1324]	[1440,1077,2058,1627]	5	hSpCas9	negative selection	9431651
41366553	41366576	17	+	27260156	TC32	viability	GCTCATCCAGAATCCTGCGCAGG	KRT33B	ENSG00000131738	-0.15244926418216076	[274]	[247,153,315,240]	-3	hSpCas9	negative selection	9431652
41367961	41367984	17	-	27260156	TC32	viability	GCAGCAAGTCTGAGAATGCCAGG	KRT33B	ENSG00000131738	-0.3501044360222415	[343]	[171,278,324,233]	-6	hSpCas9	negative selection	9495903
41365204	41365227	17	-	27260156	TC32	viability	GAGACGCACAGTCAATGCCCTGG	KRT33B	ENSG00000131738	-0.4491340983864208	[704]	[420,371,618,579]	-7	hSpCas9	negative selection	9495905
41365437	41365460	17	+	27260156	TC32	viability	CAGGGCCTCATACTGATTCCTGG	KRT33B	ENSG00000131738	0.042242832037008515	[288]	[292,183,242,417]	0	hSpCas9	negative selection	9495906
41366502	41366525	17	+	27260156	TC32	viability	CCTCCTTCAGGGACTCCATCTGG	KRT33B	ENSG00000131738	0.8092884638299771	[667]	[965,970,1429,1086]	9	hSpCas9	negative selection	9495907
41363827	41363850	17	+	27869803	HPAFII	viability after 27 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.608947289953674	[220]	[91,62,NaN]	-4	hSpCas9	negative selection	9560686
41363855	41363878	17	+	27869803	HPAFII	viability after 27 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.446289401774667	[664]	[429,514,NaN]	3	hSpCas9	negative selection	9560687
41363887	41363910	17	+	27869803	HPAFII	viability after 27 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.16597972178663456	[96]	[45,44,NaN]	-1	hSpCas9	negative selection	9560688
41363827	41363850	17	+	27869803	HPAFII	viability after 15 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.43453222244003664	[220]	[303,95,NaN]	-5	hSpCas9	negative selection	9643135
41363855	41363878	17	+	27869803	HPAFII	viability after 15 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.5133460374078349	[664]	[1460,745,NaN]	6	hSpCas9	negative selection	9643136
41363887	41363910	17	+	27869803	HPAFII	viability after 15 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.9740442311697346	[96]	[94,26,NaN]	-7	hSpCas9	negative selection	9643137
41363827	41363850	17	+	27869803	ASPC1	viability after 36 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.7102414120554994	[437]	[135,63,85]	-6	hSpCas9	negative selection	9725584
41363855	41363878	17	+	27869803	ASPC1	viability after 36 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	-0.549611623132521	[1915]	[695,328,385]	-5	hSpCas9	negative selection	9725585
41363887	41363910	17	+	27869803	ASPC1	viability after 36 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	1.566170709346665	[257]	[63,587,150]	9	hSpCas9	negative selection	9725586
41363827	41363850	17	+	27869803	PATU8988S	viability after 35 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.34404912843437935	[315]	[180,141,NaN]	4	hSpCas9	negative selection	9808033
41363855	41363878	17	+	27869803	PATU8988S	viability after 35 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	-0.47977373994976547	[1528]	[479,402,NaN]	-5	hSpCas9	negative selection	9808034
41363887	41363910	17	+	27869803	PATU8988S	viability after 35 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	0.03274329448400404	[208]	[132,38,NaN]	0	hSpCas9	negative selection	9808035
41363827	41363850	17	+	27869803	PATU8988S	viability after 31 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	0.4762137277102596	[315]	[180,167,NaN]	6	hSpCas9	negative selection	9890482
41363855	41363878	17	+	27869803	PATU8988S	viability after 31 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	-0.6506021325474804	[1528]	[262,547,NaN]	-6	hSpCas9	negative selection	9890483
41363887	41363910	17	+	27869803	PATU8988S	viability after 31 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-0.09473497676533849	[208]	[81,72,NaN]	-1	hSpCas9	negative selection	9890484
41363827	41363850	17	+	27869803	HPAFII	viability after 35 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.006884424854300991	[220]	[100,122,NaN]	0	hSpCas9	negative selection	9972931
41363855	41363878	17	+	27869803	HPAFII	viability after 35 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.692781051810686	[664]	[403,701,NaN]	4	hSpCas9	negative selection	9972932
41363887	41363910	17	+	27869803	HPAFII	viability after 35 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-1.660871411426076	[96]	[15,14,NaN]	-7	hSpCas9	negative selection	9972933
41363827	41363850	17	+	27869803	HPAFII	viability after 31 days	CCAGGGTATCTAGTACCCAAAGG	KRT33B	ENSG00000131738	-0.3403473749255007	[220]	[85,110,NaN]	-2	hSpCas9	negative selection	10055380
41363855	41363878	17	+	27869803	HPAFII	viability after 31 days	CAAGGCCCACAGCGGGAACGAGG	KRT33B	ENSG00000131738	0.4712769961229133	[664]	[447,592,NaN]	3	hSpCas9	negative selection	10055381
41363887	41363910	17	+	27869803	HPAFII	viability after 31 days	ATTGGTGACACAGGATCCAATGG	KRT33B	ENSG00000131738	-1.3075785074120194	[96]	[32,9,NaN]	-7	hSpCas9	negative selection	10055382
41365484	41365507	17	-	28162770	P31FUJ	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.12627888889044958	[137]	[176]	1	hSpCas9	negative selection	10181465
41363869	41363892	17	+	28162770	P31FUJ	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	0.09864866459149035	[150]	[189]	1	hSpCas9	negative selection	10181466
41366616	41366639	17	-	28162770	P31FUJ	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.529474478281015	[338]	[574]	6	hSpCas9	negative selection	10181467
41366595	41366618	17	-	28162770	P31FUJ	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.6108389234226037	[257]	[462]	7	hSpCas9	negative selection	10181468
41369618	41369641	17	+	28162770	P31FUJ	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.4289801594710345	[834]	[1320]	5	hSpCas9	negative selection	10181469
41366517	41366540	17	-	28162770	P31FUJ	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.5009177302481735	[177]	[295]	5	hSpCas9	negative selection	10181470
41369730	41369753	17	+	28162770	P31FUJ	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.6542642668191638	[424]	[785]	7	hSpCas9	negative selection	10181471
41367943	41367966	17	+	28162770	P31FUJ	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.5138413036541816	[207]	[348]	6	hSpCas9	negative selection	10181472
41367916	41367939	17	+	28162770	P31FUJ	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.21032760189381827	[266]	[362]	2	hSpCas9	negative selection	10181473
41366457	41366480	17	+	28162770	P31FUJ	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	-0.1735630010397025	[166]	[173]	-2	hSpCas9	negative selection	10181474
41365484	41365507	17	-	28162770	TF1	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	NaN	[NaN]	[167]	1	hSpCas9	negative selection	10350831
41363869	41363892	17	+	28162770	TF1	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10350832
41366616	41366639	17	-	28162770	TF1	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	NaN	[NaN]	[516]	1	hSpCas9	negative selection	10350833
41366595	41366618	17	-	28162770	TF1	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	NaN	[NaN]	[536]	1	hSpCas9	negative selection	10350834
41369618	41369641	17	+	28162770	TF1	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	NaN	[NaN]	[1190]	1	hSpCas9	negative selection	10350835
41366517	41366540	17	-	28162770	TF1	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	NaN	[NaN]	[197]	1	hSpCas9	negative selection	10350836
41369730	41369753	17	+	28162770	TF1	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	NaN	[NaN]	[517]	1	hSpCas9	negative selection	10350837
41367943	41367966	17	+	28162770	TF1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	NaN	[NaN]	[249]	1	hSpCas9	negative selection	10350838
41367916	41367939	17	+	28162770	TF1	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	NaN	[NaN]	[208]	1	hSpCas9	negative selection	10350839
41366457	41366480	17	+	28162770	TF1	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	NaN	[NaN]	[218]	1	hSpCas9	negative selection	10350840
41365484	41365507	17	-	28162770	SKM1	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-0.446492562929799	[36]	[47]	-4	hSpCas9	negative selection	10520197
41363869	41363892	17	+	28162770	SKM1	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.4644496934039217	[31]	[40]	-4	hSpCas9	negative selection	10520198
41366616	41366639	17	-	28162770	SKM1	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.3646195922926203	[104]	[238]	3	hSpCas9	negative selection	10520199
41366595	41366618	17	-	28162770	SKM1	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.553289622464082	[68]	[178]	5	hSpCas9	negative selection	10520200
41369618	41369641	17	+	28162770	SKM1	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.1081392791985731	[237]	[906]	8	hSpCas9	negative selection	10520201
41366517	41366540	17	-	28162770	SKM1	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	-0.41761144294267016	[67]	[89]	-3	hSpCas9	negative selection	10520202
41369730	41369753	17	+	28162770	SKM1	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.5998249669194773	[105]	[283]	6	hSpCas9	negative selection	10520203
41367943	41367966	17	+	28162770	SKM1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.8262867380679798	[51]	[162]	7	hSpCas9	negative selection	10520204
41367916	41367939	17	+	28162770	SKM1	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.444784842672896	[63]	[153]	4	hSpCas9	negative selection	10520205
41366457	41366480	17	+	28162770	SKM1	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.566268891694053	[33]	[88]	5	hSpCas9	negative selection	10520206
41365484	41365507	17	-	28162770	SKM1	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-0.446492562929799	[36]	[47]	-4	hSpCas9	negative selection	10689563
41363869	41363892	17	+	28162770	SKM1	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.4644496934039217	[31]	[40]	-4	hSpCas9	negative selection	10689564
41366616	41366639	17	-	28162770	SKM1	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.3646195922926203	[104]	[238]	3	hSpCas9	negative selection	10689565
41366595	41366618	17	-	28162770	SKM1	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.553289622464082	[68]	[178]	5	hSpCas9	negative selection	10689566
41369618	41369641	17	+	28162770	SKM1	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.1081392791985731	[237]	[906]	8	hSpCas9	negative selection	10689567
41366517	41366540	17	-	28162770	SKM1	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	-0.41761144294267016	[67]	[89]	-3	hSpCas9	negative selection	10689568
41369730	41369753	17	+	28162770	SKM1	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.5998249669194773	[105]	[283]	6	hSpCas9	negative selection	10689569
41367943	41367966	17	+	28162770	SKM1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.8262867380679798	[51]	[162]	7	hSpCas9	negative selection	10689570
41367916	41367939	17	+	28162770	SKM1	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.444784842672896	[63]	[153]	4	hSpCas9	negative selection	10689571
41366457	41366480	17	+	28162770	SKM1	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.566268891694053	[33]	[88]	5	hSpCas9	negative selection	10689572
41365484	41365507	17	-	28162770	PL21	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.6411723223011083	[164]	[111]	5	hSpCas9	negative selection	10858929
41363869	41363892	17	+	28162770	PL21	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	0.2615401591534634	[68]	[35]	2	hSpCas9	negative selection	10858930
41366616	41366639	17	-	28162770	PL21	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-0.12351522511751034	[417]	[166]	-1	hSpCas9	negative selection	10858931
41366595	41366618	17	-	28162770	PL21	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	-0.46913917216531154	[228]	[71]	-3	hSpCas9	negative selection	10858932
41369618	41369641	17	+	28162770	PL21	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.5619724965964195	[869]	[558]	5	hSpCas9	negative selection	10858933
41366517	41366540	17	-	28162770	PL21	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	-1.2342632096564548	[199]	[36]	-7	hSpCas9	negative selection	10858934
41369730	41369753	17	+	28162770	PL21	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.2239863564436878	[359]	[182]	2	hSpCas9	negative selection	10858935
41367943	41367966	17	+	28162770	PL21	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.8278065661647145	[232]	[179]	7	hSpCas9	negative selection	10858936
41367916	41367939	17	+	28162770	PL21	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.43512560267120937	[276]	[162]	4	hSpCas9	negative selection	10858937
41366457	41366480	17	+	28162770	PL21	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.8897994938771697	[61]	[49]	7	hSpCas9	negative selection	10858938
41365484	41365507	17	-	28162770	P31FUJ	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.12627888889044958	[137]	[176]	1	hSpCas9	negative selection	11028295
41363869	41363892	17	+	28162770	P31FUJ	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	0.09864866459149035	[150]	[189]	1	hSpCas9	negative selection	11028296
41366616	41366639	17	-	28162770	P31FUJ	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.529474478281015	[338]	[574]	6	hSpCas9	negative selection	11028297
41366595	41366618	17	-	28162770	P31FUJ	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.6108389234226037	[257]	[462]	7	hSpCas9	negative selection	11028298
41369618	41369641	17	+	28162770	P31FUJ	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.4289801594710345	[834]	[1320]	5	hSpCas9	negative selection	11028299
41366517	41366540	17	-	28162770	P31FUJ	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.5009177302481735	[177]	[295]	5	hSpCas9	negative selection	11028300
41369730	41369753	17	+	28162770	P31FUJ	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.6542642668191638	[424]	[785]	7	hSpCas9	negative selection	11028301
41367943	41367966	17	+	28162770	P31FUJ	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.5138413036541816	[207]	[348]	6	hSpCas9	negative selection	11028302
41367916	41367939	17	+	28162770	P31FUJ	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.21032760189381827	[266]	[362]	2	hSpCas9	negative selection	11028303
41366457	41366480	17	+	28162770	P31FUJ	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	-0.1735630010397025	[166]	[173]	-2	hSpCas9	negative selection	11028304
41365484	41365507	17	-	28162770	OCIAML5	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.20780488511340167	[58]	[122]	1	hSpCas9	negative selection	11197661
41363869	41363892	17	+	28162770	OCIAML5	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	0.07754410124460503	[83]	[159]	0	hSpCas9	negative selection	11197662
41366616	41366639	17	-	28162770	OCIAML5	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.5196145592204651	[227]	[589]	4	hSpCas9	negative selection	11197663
41366595	41366618	17	-	28162770	OCIAML5	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.009413565054575024	[212]	[386]	0	hSpCas9	negative selection	11197664
41369618	41369641	17	+	28162770	OCIAML5	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.2373237189574569	[351]	[1497]	9	hSpCas9	negative selection	11197665
41366517	41366540	17	-	28162770	OCIAML5	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.3833820032978974	[109]	[258]	3	hSpCas9	negative selection	11197666
41369730	41369753	17	+	28162770	OCIAML5	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.4667331634750733	[276]	[690]	4	hSpCas9	negative selection	11197667
41367943	41367966	17	+	28162770	OCIAML5	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.0958764094328925	[163]	[276]	0	hSpCas9	negative selection	11197668
41367916	41367939	17	+	28162770	OCIAML5	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.6657817339986224	[131]	[377]	6	hSpCas9	negative selection	11197669
41366457	41366480	17	+	28162770	OCIAML5	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	-0.5199905206005517	[84]	[106]	-4	hSpCas9	negative selection	11197670
41365484	41365507	17	-	28162770	EOL1	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-0.11427147731999364	[338]	[164]	-1	hSpCas9	negative selection	11367027
41363869	41363892	17	+	28162770	EOL1	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.42028072542690675	[126]	[49]	-3	hSpCas9	negative selection	11367028
41366616	41366639	17	-	28162770	EOL1	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.2354336956663119	[681]	[422]	2	hSpCas9	negative selection	11367029
41366595	41366618	17	-	28162770	EOL1	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	1.044977781961528	[424]	[461]	8	hSpCas9	negative selection	11367030
41369618	41369641	17	+	28162770	EOL1	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.0163211588778136	[1552]	[1654]	8	hSpCas9	negative selection	11367031
41366517	41366540	17	-	28162770	EOL1	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.4253498246276921	[399]	[282]	4	hSpCas9	negative selection	11367032
41369730	41369753	17	+	28162770	EOL1	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.23035620109462018	[431]	[266]	2	hSpCas9	negative selection	11367033
41367943	41367966	17	+	28162770	EOL1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.09119764097998573	[195]	[109]	0	hSpCas9	negative selection	11367034
41367916	41367939	17	+	28162770	EOL1	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	-0.7034834510425076	[305]	[98]	-5	hSpCas9	negative selection	11367035
41366457	41366480	17	+	28162770	EOL1	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.5300159277263321	[162]	[123]	5	hSpCas9	negative selection	11367036
41365484	41365507	17	-	28162770	MOLM13	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-1.224407163287899	[264]	[81]	-6	hSpCas9	negative selection	11536393
41363869	41363892	17	+	28162770	MOLM13	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	0.18860562406571013	[124]	[102]	1	hSpCas9	negative selection	11536394
41366616	41366639	17	-	28162770	MOLM13	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.7510614329494489	[580]	[706]	5	hSpCas9	negative selection	11536395
41366595	41366618	17	-	28162770	MOLM13	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.9052393428940202	[400]	[542]	7	hSpCas9	negative selection	11536396
41369618	41369641	17	+	28162770	MOLM13	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.2931534254337493	[994]	[1762]	8	hSpCas9	negative selection	11536397
41366517	41366540	17	-	28162770	MOLM13	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	-0.06744235145197663	[299]	[206]	0	hSpCas9	negative selection	11536398
41369730	41369753	17	+	28162770	MOLM13	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.15238755581664953	[447]	[359]	1	hSpCas9	negative selection	11536399
41367943	41367966	17	+	28162770	MOLM13	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.11356329625477896	[348]	[272]	0	hSpCas9	negative selection	11536400
41367916	41367939	17	+	28162770	MOLM13	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	-0.0828032170918313	[415]	[283]	0	hSpCas9	negative selection	11536401
41366457	41366480	17	+	28162770	MOLM13	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	1.3634201149885494	[135]	[252]	9	hSpCas9	negative selection	11536402
41365484	41365507	17	-	28162770	HEL	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.268059070337654	[187]	[144]	2	hSpCas9	negative selection	11705759
41363869	41363892	17	+	28162770	HEL	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.357261167999643	[121]	[60]	-3	hSpCas9	negative selection	11705760
41366616	41366639	17	-	28162770	HEL	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	1.3170091669531385	[474]	[757]	9	hSpCas9	negative selection	11705761
41366595	41366618	17	-	28162770	HEL	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.8955774707282622	[354]	[422]	7	hSpCas9	negative selection	11705762
41369618	41369641	17	+	28162770	HEL	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.2017885223137788	[954]	[1406]	9	hSpCas9	negative selection	11705763
41366517	41366540	17	-	28162770	HEL	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	1.255077771652818	[260]	[398]	9	hSpCas9	negative selection	11705764
41369730	41369753	17	+	28162770	HEL	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.9908926531236212	[446]	[568]	8	hSpCas9	negative selection	11705765
41367943	41367966	17	+	28162770	HEL	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	1.195758440218759	[273]	[401]	9	hSpCas9	negative selection	11705766
41367916	41367939	17	+	28162770	HEL	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.15344677802809026	[298]	[212]	1	hSpCas9	negative selection	11705767
41366457	41366480	17	+	28162770	HEL	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.911673839273835	[121]	[146]	7	hSpCas9	negative selection	11705768
41365484	41365507	17	-	28162770	MV411	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-1.4789973758912611	[181]	[54]	-7	hSpCas9	negative selection	11875125
41363869	41363892	17	+	28162770	MV411	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.2979965857517437	[107]	[73]	-2	hSpCas9	negative selection	11875126
41366616	41366639	17	-	28162770	MV411	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.20475115168122526	[342]	[332]	1	hSpCas9	negative selection	11875127
41366595	41366618	17	-	28162770	MV411	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	-0.10895395367280877	[232]	[181]	-1	hSpCas9	negative selection	11875128
41369618	41369641	17	+	28162770	MV411	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.3423491978082422	[624]	[1334]	9	hSpCas9	negative selection	11875129
41366517	41366540	17	-	28162770	MV411	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.6662666292239934	[189]	[253]	6	hSpCas9	negative selection	11875130
41369730	41369753	17	+	28162770	MV411	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.3701974441464073	[303]	[330]	3	hSpCas9	negative selection	11875131
41367943	41367966	17	+	28162770	MV411	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.4358826401958854	[171]	[195]	4	hSpCas9	negative selection	11875132
41367916	41367939	17	+	28162770	MV411	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.7455068825377517	[210]	[297]	6	hSpCas9	negative selection	11875133
41366457	41366480	17	+	28162770	MV411	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.5929341168085421	[84]	[107]	5	hSpCas9	negative selection	11875134
41365484	41365507	17	-	28162770	MONOMAC1	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	1.4172696152437467	[145]	[446]	9	hSpCas9	negative selection	12044491
41363869	41363892	17	+	28162770	MONOMAC1	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	0.5246619904533418	[56]	[93]	5	hSpCas9	negative selection	12044492
41366616	41366639	17	-	28162770	MONOMAC1	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.0901568316987198	[226]	[276]	0	hSpCas9	negative selection	12044493
41366595	41366618	17	-	28162770	MONOMAC1	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.205061596511792	[195]	[258]	2	hSpCas9	negative selection	12044494
41369618	41369641	17	+	28162770	MONOMAC1	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.32459971829277334	[488]	[701]	3	hSpCas9	negative selection	12044495
41366517	41366540	17	-	28162770	MONOMAC1	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	-0.314076268249773	[153]	[141]	-3	hSpCas9	negative selection	12044496
41369730	41369753	17	+	28162770	MONOMAC1	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	1.041865896301342	[210]	[497]	8	hSpCas9	negative selection	12044497
41367943	41367966	17	+	28162770	MONOMAC1	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	-0.20792516320228982	[132]	[131]	-2	hSpCas9	negative selection	12044498
41367916	41367939	17	+	28162770	MONOMAC1	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	-0.11282384315646843	[182]	[193]	-1	hSpCas9	negative selection	12044499
41366457	41366480	17	+	28162770	MONOMAC1	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.2800103144947149	[73]	[102]	3	hSpCas9	negative selection	12044500
41365484	41365507	17	-	28162770	OCIAML2	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	-0.6248007553699214	[36]	[132]	-5	hSpCas9	negative selection	12213857
41363869	41363892	17	+	28162770	OCIAML2	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	-0.361005334067663	[18]	[81]	-3	hSpCas9	negative selection	12213858
41366616	41366639	17	-	28162770	OCIAML2	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	0.1411742876976363	[70]	[433]	1	hSpCas9	negative selection	12213859
41366595	41366618	17	-	28162770	OCIAML2	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	0.609743591221859	[47]	[405]	6	hSpCas9	negative selection	12213860
41369618	41369641	17	+	28162770	OCIAML2	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	0.7895586263684051	[147]	[1417]	7	hSpCas9	negative selection	12213861
41366517	41366540	17	-	28162770	OCIAML2	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.6059117296308318	[38]	[328]	6	hSpCas9	negative selection	12213862
41369730	41369753	17	+	28162770	OCIAML2	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.6093694968230587	[56]	[481]	6	hSpCas9	negative selection	12213863
41367943	41367966	17	+	28162770	OCIAML2	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.057301730442615884	[42]	[247]	0	hSpCas9	negative selection	12213864
41367916	41367939	17	+	28162770	OCIAML2	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	0.9924403704584841	[35]	[396]	8	hSpCas9	negative selection	12213865
41366457	41366480	17	+	28162770	OCIAML2	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.22451559322941783	[20]	[135]	2	hSpCas9	negative selection	12213866
41365484	41365507	17	-	28162770	OCIAML3	viability	GGTGGACGCTGCTCCCGCTGTGG	KRT33B	ENSG00000131738	0.34876749098288673	[44]	[172]	3	hSpCas9	negative selection	12383223
41363869	41363892	17	+	28162770	OCIAML3	viability	GGAACGAGGACCACAAGGATTGG	KRT33B	ENSG00000131738	1.15322628929587	[41]	[281]	8	hSpCas9	negative selection	12383224
41366616	41366639	17	-	28162770	OCIAML3	viability	CTGTGTGTGCAGGTACCAGACGG	KRT33B	ENSG00000131738	-0.466895722420824	[113]	[248]	-4	hSpCas9	negative selection	12383225
41366595	41366618	17	-	28162770	OCIAML3	viability	GGAGCAGTCCCTGCGGCAGCTGG	KRT33B	ENSG00000131738	-0.428421574606188	[73]	[165]	-3	hSpCas9	negative selection	12383226
41369618	41369641	17	+	28162770	OCIAML3	viability	TGCAGTTGCTCACATTGGCAGGG	KRT33B	ENSG00000131738	1.1225145646302708	[198]	[1307]	8	hSpCas9	negative selection	12383227
41366517	41366540	17	-	28162770	OCIAML3	viability	GTCTGACCTGGAGGCCCAGATGG	KRT33B	ENSG00000131738	0.4911597429385141	[36]	[156]	4	hSpCas9	negative selection	12383228
41369730	41369753	17	+	28162770	OCIAML3	viability	CAGGCAGAAGTTGTAGGGCATGG	KRT33B	ENSG00000131738	0.15997393085764422	[117]	[397]	1	hSpCas9	negative selection	12383229
41367943	41367966	17	+	28162770	OCIAML3	viability	GTCGATCTGCACCACCAGCCTGG	KRT33B	ENSG00000131738	0.2591509713465657	[61]	[223]	2	hSpCas9	negative selection	12383230
41367916	41367939	17	+	28162770	OCIAML3	viability	GAAGTCATCTGCAGCCAGCTTGG	KRT33B	ENSG00000131738	1.2261713220910246	[63]	[451]	8	hSpCas9	negative selection	12383231
41366457	41366480	17	+	28162770	OCIAML3	viability	CTGGGACTCTTACCTGCTCATGG	KRT33B	ENSG00000131738	0.8726919787771733	[35]	[198]	7	hSpCas9	negative selection	12383232