Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3851
• Symbol:KRT4
• Description:keratin 4

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52814003	52814026	12	+	26472758	Jiyoye	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.2681989683570629	[97]	[88]	2	hSpCas9	negative selection	86558
52814027	52814050	12	-	26472758	Jiyoye	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.15719712849752576	[43]	[36]	1	hSpCas9	negative selection	86559
52813985	52814008	12	-	26472758	Jiyoye	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.05399635263407143	[174]	[136]	0	hSpCas9	negative selection	86560
52811845	52811868	12	+	26472758	Jiyoye	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	1.1241662759108135	[159]	[262]	7	hSpCas9	negative selection	86561
52811779	52811802	12	-	26472758	Jiyoye	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-1.0932536090036151	[115]	[40]	-6	hSpCas9	negative selection	86562
52813847	52813870	12	-	26472758	Jiyoye	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.4194537112843101	[233]	[235]	3	hSpCas9	negative selection	86563
52813766	52813789	12	-	26472758	Jiyoye	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	-0.7427652454822843	[232]	[104]	-5	hSpCas9	negative selection	86564
52809373	52809396	12	+	26472758	Jiyoye	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.6966819987008583	[35]	[43]	5	hSpCas9	negative selection	86565
52808754	52808777	12	-	26472758	Jiyoye	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	-2.6517183075476956	[24]	[2]	-9	hSpCas9	negative selection	86566
52807348	52807371	12	+	26472758	Jiyoye	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.17730783960727892	[128]	[109]	1	hSpCas9	negative selection	86567
52814003	52814026	12	+	26472758	KBM7	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.2935265923847693	[254,185]	[84,161]	3	hSpCas9	negative selection	277676
52814027	52814050	12	-	26472758	KBM7	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.5159183532642818	[233,174]	[161,112]	5	hSpCas9	negative selection	277677
52813985	52814008	12	-	26472758	KBM7	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.2340600332277808	[539,368]	[233,259]	2	hSpCas9	negative selection	277678
52811845	52811868	12	+	26472758	KBM7	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.5440980464371783	[1286,757]	[659,708]	6	hSpCas9	negative selection	277679
52811779	52811802	12	-	26472758	KBM7	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-0.19014361743830477	[325,181]	[136,70]	-2	hSpCas9	negative selection	277680
52813847	52813870	12	-	26472758	KBM7	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.4124041200465399	[991,853]	[632,524]	4	hSpCas9	negative selection	277681
52813766	52813789	12	-	26472758	KBM7	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.1266935408967475	[633,508]	[309,274]	1	hSpCas9	negative selection	277682
52809373	52809396	12	+	26472758	KBM7	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	-0.2572543510918788	[200,272]	[101,88]	-2	hSpCas9	negative selection	277683
52808754	52808777	12	-	26472758	KBM7	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	0.3422616125939526	[123,99]	[87,46]	3	hSpCas9	negative selection	277684
52807348	52807371	12	+	26472758	KBM7	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	1.0519502220615413	[622,578]	[783,409]	9	hSpCas9	negative selection	277685
52814003	52814026	12	+	26472758	Raji	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	2.1073835353735997	[65]	[65]	9	hSpCas9	negative selection	468794
52814027	52814050	12	-	26472758	Raji	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.4766173450393184	[95]	[30]	4	hSpCas9	negative selection	468795
52813985	52814008	12	-	26472758	Raji	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.30669234359700626	[323]	[92]	3	hSpCas9	negative selection	468796
52811845	52811868	12	+	26472758	Raji	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.42443124396134846	[532]	[165]	4	hSpCas9	negative selection	468797
52811779	52811802	12	-	26472758	Raji	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-0.06254146606871291	[80]	[17]	0	hSpCas9	negative selection	468798
52813847	52813870	12	-	26472758	Raji	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	1.211720195188335	[239]	[128]	9	hSpCas9	negative selection	468799
52813766	52813789	12	-	26472758	Raji	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.0773263015174197	[387]	[94]	0	hSpCas9	negative selection	468800
52809373	52809396	12	+	26472758	Raji	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	-0.47757896534755684	[119]	[19]	-4	hSpCas9	negative selection	468801
52808754	52808777	12	-	26472758	Raji	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	1.7512397251483243	[31]	[24]	9	hSpCas9	negative selection	468802
52807348	52807371	12	+	26472758	Raji	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.8979301697446497	[258]	[111]	7	hSpCas9	negative selection	468803
52814003	52814026	12	+	26472758	K562	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.5350088560208022	[120]	[147]	4	hSpCas9	negative selection	659912
52814027	52814050	12	-	26472758	K562	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.9010422135150494	[143]	[226]	7	hSpCas9	negative selection	659913
52813985	52814008	12	-	26472758	K562	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.19845287371426648	[286]	[277]	1	hSpCas9	negative selection	659914
52811845	52811868	12	+	26472758	K562	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	-0.07243837767349337	[922]	[740]	0	hSpCas9	negative selection	659915
52811779	52811802	12	-	26472758	K562	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	1.4036173225157005	[149]	[334]	9	hSpCas9	negative selection	659916
52813847	52813870	12	-	26472758	K562	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.12478362428596623	[665]	[612]	0	hSpCas9	negative selection	659917
52813766	52813789	12	-	26472758	K562	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.5243449128990137	[466]	[566]	4	hSpCas9	negative selection	659918
52809373	52809396	12	+	26472758	K562	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.286729532524411	[167]	[172]	2	hSpCas9	negative selection	659919
52808754	52808777	12	-	26472758	K562	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	-3.583400296950873	[70]	[4]	-8	hSpCas9	negative selection	659920
52807348	52807371	12	+	26472758	K562	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.1988081311461472	[481]	[466]	1	hSpCas9	negative selection	659921
52807208	52807231	12	-	26627737	DLD1	viability	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.614322249759824	[1325]	[143,535,160]	-6	hSpCas9	negative selection	784297
52807777	52807800	12	-	26627737	DLD1	viability	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	2.4257828532466235	[381]	[1527,280,171]	9	hSpCas9	negative selection	784298
52808808	52808831	12	+	26627737	DLD1	viability	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.13517399481076375	[890]	[380,400,161]	1	hSpCas9	negative selection	784299
52811816	52811839	12	+	26627737	DLD1	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.5359683375807563	[390]	[158,175,193]	5	hSpCas9	negative selection	784300
52813978	52814001	12	+	26627737	DLD1	viability	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.11429862863312401	[805]	[173,299,227]	-1	hSpCas9	negative selection	784301
52814131	52814154	12	-	26627737	DLD1	viability	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.10906941818039712	[395]	[78,192,80]	-1	hSpCas9	negative selection	784302
52807208	52807231	12	-	26627737	GBM cells	viability after 5 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.0630332546467921	[414]	[216,247]	1	hSpCas9	negative selection	866612
52807777	52807800	12	-	26627737	GBM cells	viability after 5 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.6484247223710056	[228]	[246,137]	8	hSpCas9	negative selection	866613
52808808	52808831	12	+	26627737	GBM cells	viability after 5 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.7505220349930146	[265]	[287,191]	8	hSpCas9	negative selection	866614
52811816	52811839	12	+	26627737	GBM cells	viability after 5 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.5332644025690053	[267]	[235,179]	7	hSpCas9	negative selection	866615
52813978	52814001	12	+	26627737	GBM cells	viability after 5 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.26382789473869284	[409]	[226,300]	4	hSpCas9	negative selection	866616
52814131	52814154	12	-	26627737	GBM cells	viability after 5 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.014794586935825194	[274]	[180,116]	0	hSpCas9	negative selection	866617
52807208	52807231	12	-	26627737	GBM cells	viability after 13 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.23374267088173528	[414]	[293,240]	3	hSpCas9	negative selection	948927
52807777	52807800	12	-	26627737	GBM cells	viability after 13 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.40774209328358374	[228]	[171,158]	5	hSpCas9	negative selection	948928
52808808	52808831	12	+	26627737	GBM cells	viability after 13 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.6484071121899317	[265]	[255,201]	7	hSpCas9	negative selection	948929
52811816	52811839	12	+	26627737	GBM cells	viability after 13 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.45269185947234003	[267]	[214,185]	6	hSpCas9	negative selection	948930
52813978	52814001	12	+	26627737	GBM cells	viability after 13 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.017912127672822464	[409]	[286,174]	0	hSpCas9	negative selection	948931
52814131	52814154	12	-	26627737	GBM cells	viability after 13 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.20680592930466352	[274]	[169,173]	2	hSpCas9	negative selection	948932
52807208	52807231	12	-	26627737	GBM cells	viability after 21 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.16169023882222877	[414]	[270,234]	1	hSpCas9	negative selection	1031242
52807777	52807800	12	-	26627737	GBM cells	viability after 21 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.5173931958908498	[228]	[187,168]	5	hSpCas9	negative selection	1031243
52808808	52808831	12	+	26627737	GBM cells	viability after 21 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.15317698290220028	[265]	[155,164]	1	hSpCas9	negative selection	1031244
52811816	52811839	12	+	26627737	GBM cells	viability after 21 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.2382637307149593	[267]	[165,176]	2	hSpCas9	negative selection	1031245
52813978	52814001	12	+	26627737	GBM cells	viability after 21 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.012181414980954486	[409]	[244,205]	0	hSpCas9	negative selection	1031246
52814131	52814154	12	-	26627737	GBM cells	viability after 21 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.473449426482492	[274]	[208,205]	5	hSpCas9	negative selection	1031247
52807208	52807231	12	-	26627737	RPE1	viability after 9 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.6804787929872311	[914]	[445,475]	4	hSpCas9	negative selection	1113557
52807777	52807800	12	-	26627737	RPE1	viability after 9 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.32426841436702036	[1199]	[496,435]	2	hSpCas9	negative selection	1113558
52808808	52808831	12	+	26627737	RPE1	viability after 9 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	1.6636322442019518	[524]	[504,540]	8	hSpCas9	negative selection	1113559
52811816	52811839	12	+	26627737	RPE1	viability after 9 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.9152005618900994	[1514]	[347,126]	-6	hSpCas9	negative selection	1113560
52813978	52814001	12	+	26627737	RPE1	viability after 9 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.1002530818348194	[1191]	[255,466]	0	hSpCas9	negative selection	1113561
52814131	52814154	12	-	26627737	RPE1	viability after 9 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.13150737166570264	[918]	[305,326]	0	hSpCas9	negative selection	1113562
52807208	52807231	12	-	26627737	RPE1	viability after 12 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.09802924961811754	[914]	[266,258]	0	hSpCas9	negative selection	1195872
52807777	52807800	12	-	26627737	RPE1	viability after 12 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	-0.11630784758093016	[1199]	[277,317]	-1	hSpCas9	negative selection	1195873
52808808	52808831	12	+	26627737	RPE1	viability after 12 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	1.4045159164584924	[524]	[233,520]	7	hSpCas9	negative selection	1195874
52811816	52811839	12	+	26627737	RPE1	viability after 12 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.24224669090746442	[1514]	[364,321]	-2	hSpCas9	negative selection	1195875
52813978	52814001	12	+	26627737	RPE1	viability after 12 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.4498766868414553	[1191]	[215,253]	-3	hSpCas9	negative selection	1195876
52814131	52814154	12	-	26627737	RPE1	viability after 12 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.41776292793033526	[918]	[340,317]	2	hSpCas9	negative selection	1195877
52807208	52807231	12	-	26627737	RPE1	viability after 15 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.07238302947127354	[914]	[292,200]	0	hSpCas9	negative selection	1278187
52807777	52807800	12	-	26627737	RPE1	viability after 15 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	-0.085539578532147	[1199]	[352,287]	0	hSpCas9	negative selection	1278188
52808808	52808831	12	+	26627737	RPE1	viability after 15 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	1.8720537620385391	[524]	[676,414]	8	hSpCas9	negative selection	1278189
52811816	52811839	12	+	26627737	RPE1	viability after 15 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.27271733283766664	[1514]	[340,367]	-2	hSpCas9	negative selection	1278190
52813978	52814001	12	+	26627737	RPE1	viability after 15 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.34526964709036845	[1191]	[325,206]	-2	hSpCas9	negative selection	1278191
52814131	52814154	12	-	26627737	RPE1	viability after 15 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.3676075738678169	[918]	[227,438]	2	hSpCas9	negative selection	1278192
52807208	52807231	12	-	26627737	RPE1	viability after 18 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.2829087857656118	[914]	[341,255]	1	hSpCas9	negative selection	1360502
52807777	52807800	12	-	26627737	RPE1	viability after 18 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	-0.10099475756757903	[1199]	[314,287]	0	hSpCas9	negative selection	1360503
52808808	52808831	12	+	26627737	RPE1	viability after 18 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	1.867951482751607	[524]	[375,667]	8	hSpCas9	negative selection	1360504
52811816	52811839	12	+	26627737	RPE1	viability after 18 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.4850005766757885	[1514]	[251,334]	-3	hSpCas9	negative selection	1360505
52813978	52814001	12	+	26627737	RPE1	viability after 18 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.2043745165186172	[1191]	[313,241]	-1	hSpCas9	negative selection	1360506
52814131	52814154	12	-	26627737	RPE1	viability after 18 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.2211932928740153	[918]	[262,316]	1	hSpCas9	negative selection	1360507
52807208	52807231	12	-	26627737	HeLa	viability after 8 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.9750436577227476	[371]	[282,377,287]	7	hSpCas9	negative selection	1442817
52807777	52807800	12	-	26627737	HeLa	viability after 8 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.23698187705556983	[298]	[69,178,189]	2	hSpCas9	negative selection	1442818
52808808	52808831	12	+	26627737	HeLa	viability after 8 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-0.5771461266538649	[793]	[298,199,211]	-5	hSpCas9	negative selection	1442819
52811816	52811839	12	+	26627737	HeLa	viability after 8 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.6317997455656703	[734]	[330,247,76]	-6	hSpCas9	negative selection	1442820
52813978	52814001	12	+	26627737	HeLa	viability after 8 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.016986244006562734	[554]	[211,210,298]	0	hSpCas9	negative selection	1442821
52814131	52814154	12	-	26627737	HeLa	viability after 8 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.42166816469411667	[656]	[250,86,303]	-4	hSpCas9	negative selection	1442822
52807208	52807231	12	-	26627737	HeLa	viability after 12 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	1.0750095685975465	[371]	[370,238,371]	7	hSpCas9	negative selection	1525132
52807777	52807800	12	-	26627737	HeLa	viability after 12 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	-0.21243258354268152	[298]	[28,131,153]	-2	hSpCas9	negative selection	1525133
52808808	52808831	12	+	26627737	HeLa	viability after 12 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-1.0463172678293406	[793]	[118,87,275]	-7	hSpCas9	negative selection	1525134
52811816	52811839	12	+	26627737	HeLa	viability after 12 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.3944324767171239	[734]	[223,259,205]	-4	hSpCas9	negative selection	1525135
52813978	52814001	12	+	26627737	HeLa	viability after 12 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.006190778574779399	[554]	[275,214,202]	0	hSpCas9	negative selection	1525136
52814131	52814154	12	-	26627737	HeLa	viability after 12 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.6076756532149877	[656]	[236,123,180]	-5	hSpCas9	negative selection	1525137
52807208	52807231	12	-	26627737	HeLa	viability after 15 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	1.2041647260569714	[371]	[465,281,292]	8	hSpCas9	negative selection	1607447
52807777	52807800	12	-	26627737	HeLa	viability after 15 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.5080275517454078	[298]	[177,146,195]	4	hSpCas9	negative selection	1607448
52808808	52808831	12	+	26627737	HeLa	viability after 15 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-0.21098576855654405	[793]	[236,156,457]	-2	hSpCas9	negative selection	1607449
52811816	52811839	12	+	26627737	HeLa	viability after 15 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.3241349886457191	[734]	[204,254,258]	-3	hSpCas9	negative selection	1607450
52813978	52814001	12	+	26627737	HeLa	viability after 15 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.0429457607187852	[554]	[66,287,311]	0	hSpCas9	negative selection	1607451
52814131	52814154	12	-	26627737	HeLa	viability after 15 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.25401148155258524	[656]	[241,213,215]	-2	hSpCas9	negative selection	1607452
52807208	52807231	12	-	26627737	HeLa	viability after 18 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	1.242189033218969	[371]	[323,241,292]	8	hSpCas9	negative selection	1689762
52807777	52807800	12	-	26627737	HeLa	viability after 18 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.4467239919939606	[298]	[105,120,195]	3	hSpCas9	negative selection	1689763
52808808	52808831	12	+	26627737	HeLa	viability after 18 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-0.22277105758513294	[793]	[152,131,457]	-2	hSpCas9	negative selection	1689764
52811816	52811839	12	+	26627737	HeLa	viability after 18 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.301552837884526	[734]	[140,215,258]	-3	hSpCas9	negative selection	1689765
52813978	52814001	12	+	26627737	HeLa	viability after 18 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.027914039469393692	[554]	[44,243,311]	0	hSpCas9	negative selection	1689766
52814131	52814154	12	-	26627737	HeLa	viability after 18 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.25511029123449436	[656]	[158,180,215]	-2	hSpCas9	negative selection	1689767
52807208	52807231	12	-	26627737	HCT116	viability after 6 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.5304682482265238	[973]	[47,137]	-3	hSpCas9	negative selection	1772077
52807777	52807800	12	-	26627737	HCT116	viability after 6 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	-0.6675624599644456	[633]	[103,39]	-4	hSpCas9	negative selection	1772078
52808808	52808831	12	+	26627737	HCT116	viability after 6 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-0.06256002401540439	[1012]	[127,165]	0	hSpCas9	negative selection	1772079
52811816	52811839	12	+	26627737	HCT116	viability after 6 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.6729863971930876	[853]	[302,164]	4	hSpCas9	negative selection	1772080
52813978	52814001	12	+	26627737	HCT116	viability after 6 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	-0.5307280513963599	[793]	[204,20]	-3	hSpCas9	negative selection	1772081
52814131	52814154	12	-	26627737	HCT116	viability after 6 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.26513832986984565	[612]	[187,75]	1	hSpCas9	negative selection	1772082
52807208	52807231	12	-	26627737	HCT116	viability after 8 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.21966739011459646	[417]	[284,174,343]	2	hSpCas9	negative selection	1854392
52807777	52807800	12	-	26627737	HCT116	viability after 8 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.12091630221588866	[256]	[111,175,172]	1	hSpCas9	negative selection	1854393
52808808	52808831	12	+	26627737	HCT116	viability after 8 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.4160082131044586	[377]	[201,322,306]	4	hSpCas9	negative selection	1854394
52811816	52811839	12	+	26627737	HCT116	viability after 8 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.5136491419369918	[312]	[291,241,205]	5	hSpCas9	negative selection	1854395
52813978	52814001	12	+	26627737	HCT116	viability after 8 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	1.1270661289519073	[239]	[200,377,285]	8	hSpCas9	negative selection	1854396
52814131	52814154	12	-	26627737	HCT116	viability after 8 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.6175575695714965	[493]	[105,166,256]	-6	hSpCas9	negative selection	1854397
52807208	52807231	12	-	26627737	HCT116	viability after 9 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.37102534240473467	[973]	[161,231]	-3	hSpCas9	negative selection	1936707
52807777	52807800	12	-	26627737	HCT116	viability after 9 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.49441449117649416	[633]	[271,211]	3	hSpCas9	negative selection	1936708
52808808	52808831	12	+	26627737	HCT116	viability after 9 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-1.8085966921402474	[1012]	[98,59]	-8	hSpCas9	negative selection	1936709
52811816	52811839	12	+	26627737	HCT116	viability after 9 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.6218173932192661	[853]	[389,319]	4	hSpCas9	negative selection	1936710
52813978	52814001	12	+	26627737	HCT116	viability after 9 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.09085024063626734	[793]	[222,227]	0	hSpCas9	negative selection	1936711
52814131	52814154	12	-	26627737	HCT116	viability after 9 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-1.4961003421074894	[612]	[114,12]	-8	hSpCas9	negative selection	1936712
52807208	52807231	12	-	26627737	HCT116	viability after 12 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.5175021807863366	[417]	[312,211,415]	5	hSpCas9	negative selection	2019022
52807777	52807800	12	-	26627737	HCT116	viability after 12 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.6158793725355053	[256]	[168,236,218]	6	hSpCas9	negative selection	2019023
52808808	52808831	12	+	26627737	HCT116	viability after 12 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.5648330306549019	[377]	[215,360,312]	5	hSpCas9	negative selection	2019024
52811816	52811839	12	+	26627737	HCT116	viability after 12 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.1485951894413991	[312]	[119,244,188]	1	hSpCas9	negative selection	2019025
52813978	52814001	12	+	26627737	HCT116	viability after 12 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.7495481179087484	[239]	[250,222,158]	6	hSpCas9	negative selection	2019026
52814131	52814154	12	-	26627737	HCT116	viability after 12 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.44133711166628004	[493]	[166,244,164]	-5	hSpCas9	negative selection	2019027
52807208	52807231	12	-	26627737	HCT116	viability after 15 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.3731386624951315	[417]	[241,57,261]	-4	hSpCas9	negative selection	2101337
52807777	52807800	12	-	26627737	HCT116	viability after 15 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.7626943714049406	[256]	[134,334,266]	6	hSpCas9	negative selection	2101338
52808808	52808831	12	+	26627737	HCT116	viability after 15 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.5072152937559045	[377]	[182,389,336]	5	hSpCas9	negative selection	2101339
52811816	52811839	12	+	26627737	HCT116	viability after 15 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.3473730967610403	[312]	[121,314,235]	3	hSpCas9	negative selection	2101340
52813978	52814001	12	+	26627737	HCT116	viability after 15 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	1.1950373487396408	[239]	[399,326,230]	8	hSpCas9	negative selection	2101341
52814131	52814154	12	-	26627737	HCT116	viability after 15 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.5826275621331026	[493]	[210,174,184]	-6	hSpCas9	negative selection	2101342
52807208	52807231	12	-	26627737	HCT116	viability after 18 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.3072044838594107	[417]	[234,107,149]	-3	hSpCas9	negative selection	2183652
52807777	52807800	12	-	26627737	HCT116	viability after 18 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.8179563050926192	[256]	[158,295,195]	6	hSpCas9	negative selection	2183653
52808808	52808831	12	+	26627737	HCT116	viability after 18 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.5877231196865371	[377]	[167,274,385]	5	hSpCas9	negative selection	2183654
52811816	52811839	12	+	26627737	HCT116	viability after 18 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.45014734657604494	[312]	[78,91,164]	-4	hSpCas9	negative selection	2183655
52813978	52814001	12	+	26627737	HCT116	viability after 18 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.7208451660528079	[239]	[121,276,167]	6	hSpCas9	negative selection	2183656
52814131	52814154	12	-	26627737	HCT116	viability after 18 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.3171343304179153	[493]	[190,226,152]	-3	hSpCas9	negative selection	2183657
52814262	52814285	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACACACCTACAGAAGTCATCTGG	KRT4	ENSG00000170477	1.416425539273166	[78,465]	[16,317]	5	dCas9-VP64	positive selection	2429993
52814214	52814237	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGGATGGGCTTGTGCCAAGGG	KRT4	ENSG00000170477	-0.6626581697862561	[60,290]	[6,42]	-3	dCas9-VP64	positive selection	2429994
52814236	52814259	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GTGACATGCTCAACGGGTGCGGG	KRT4	ENSG00000170477	1.123452001530994	[46,16]	[25,2]	4	dCas9-VP64	positive selection	2429995
52814262	52814285	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACACACCTACAGAAGTCATCTGG	KRT4	ENSG00000170477	-0.2823424261082138	[214,181]	[48,56]	-3	dCas9-VP64	positive selection	2525248
52814214	52814237	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGGATGGGCTTGTGCCAAGGG	KRT4	ENSG00000170477	-0.130512020095924	[349,116]	[126,15]	-1	dCas9-VP64	positive selection	2525249
52814236	52814259	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GTGACATGCTCAACGGGTGCGGG	KRT4	ENSG00000170477	0.26037693663409633	[180,174]	[64,73]	2	dCas9-VP64	positive selection	2525250
52814004	52814027	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.4295957270750828	[1,1]	[2,1]	8	hSpCas9	positive selection	2998221
52811846	52811869	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	-0.03612348079598754	[3,2]	[3,1]	0	hSpCas9	positive selection	2998222
52813672	52813695	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCAGGGTCAATCTCCACGTGG	KRT4	ENSG00000170477	-0.08771736279480336	[0,1]	[1,0]	-1	hSpCas9	positive selection	2998223
52813653	52813676	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAGATCCAGAAAGTCCGGACGG	KRT4	ENSG00000170477	0.10872083147292633	[5,4]	[4,4]	2	hSpCas9	positive selection	2998224
52814004	52814027	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	-0.578387096036892	[1,1]	[1,0]	-7	hSpCas9	positive selection	3066079
52811846	52811869	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.058191117545517784	[3,3]	[3,1]	1	hSpCas9	positive selection	3066080
52813672	52813695	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCAGGGTCAATCTCCACGTGG	KRT4	ENSG00000170477	0.27297683209523504	[0,0]	[1,0]	5	hSpCas9	positive selection	3066081
52813653	52813676	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAGATCCAGAAAGTCCGGACGG	KRT4	ENSG00000170477	0.40370589443029997	[5,5]	[4,5]	7	hSpCas9	positive selection	3066082
52811852	52811875		-	24336571	A375	resistance to PLX after 7 days	AGACCTACCTCAGTGTCCTGAGG	KRT4	ENSG00000170477	-0.08376258449985285	[5,4]	[4,4]	-2	hSpCas9	positive selection	3123793
52810767	52810790		-	24336571	A375	resistance to PLX after 7 days	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.11068947112682925	[19,16]	[16,22]	3	hSpCas9	positive selection	3123794
52811816	52811839		+	24336571	A375	resistance to PLX after 7 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.18150259291237192	[7,8]	[6,6]	-6	hSpCas9	positive selection	3123795
52810762	52810785		+	24336571	A375	resistance to PLX after 7 days	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.18749414994975178	[20,19]	[16,17]	-6	hSpCas9	positive selection	3123796
52811852	52811875		-	24336571	A375	resistance to PLX after 14 days	AGACCTACCTCAGTGTCCTGAGG	KRT4	ENSG00000170477	0.32293089877933867	[4,3]	[1,1]	3	hSpCas9	positive selection	3181586
52810767	52810790		-	24336571	A375	resistance to PLX after 14 days	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.5725383856366675	[19,14]	[14,8]	5	hSpCas9	positive selection	3181587
52811816	52811839		+	24336571	A375	resistance to PLX after 14 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.6245715568185983	[9,9]	[2,1]	-7	hSpCas9	positive selection	3181588
52810762	52810785		+	24336571	A375	resistance to PLX after 14 days	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.4928146278319779	[20,17]	[5,5]	-6	hSpCas9	positive selection	3181589
52811852	52811875		-	24336571	A375	viability after 7 days	AGACCTACCTCAGTGTCCTGAGG	KRT4	ENSG00000170477	0.49275390186182655	[3]	[5,4]	7	hSpCas9	negative selection	3239379
52810767	52810790		-	24336571	A375	viability after 7 days	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.48125114421805354	[13]	[19,16]	7	hSpCas9	negative selection	3239380
52811816	52811839		+	24336571	A375	viability after 7 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.045118028224532036	[8]	[7,8]	0	hSpCas9	negative selection	3239381
52810762	52810785		+	24336571	A375	viability after 7 days	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.02820490011016563	[21]	[20,19]	0	hSpCas9	negative selection	3239382
52811852	52811875		-	24336571	A375	viability after 14 days	AGACCTACCTCAGTGTCCTGAGG	KRT4	ENSG00000170477	0.18628282414779762	[3]	[4,3]	2	hSpCas9	negative selection	3297172
52810767	52810790		-	24336571	A375	viability after 14 days	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.3937751086633333	[13]	[19,14]	5	hSpCas9	negative selection	3297173
52811816	52811839		+	24336571	A375	viability after 14 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.21278992328700774	[8]	[9,9]	2	hSpCas9	negative selection	3297174
52810762	52810785		+	24336571	A375	viability after 14 days	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.0874270408805129	[21]	[20,17]	-1	hSpCas9	negative selection	3297175
52807348	52807371	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.14355322483634927	[168,168]	[0,0]	-1	hSpCas9	positive selection	3376321
52810767	52810790	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-1.1220521556254273	[332,332]	[0,0]	-7	hSpCas9	positive selection	3376322
52811774	52811797	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.07741712143090065	[144,144]	[0,0]	0	hSpCas9	positive selection	3376323
52814003	52814026	12	+	26780180	HT29	viability (Avana library 4 designs)	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.814660491467473	[]	[]	3	hSpCas9	negative selection	3435673
52811845	52811868	12	+	26780180	HT29	viability (Avana library 4 designs)	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	1.51874649405288	[]	[]	6	hSpCas9	negative selection	3435674
52813671	52813694	12	+	26780180	HT29	viability (Avana library 4 designs)	TCTCAGGGTCAATCTCCACGTGG	KRT4	ENSG00000170477	1.21138939759383	[]	[]	5	hSpCas9	negative selection	3435675
52813653	52813676	12	-	26780180	HT29	viability (Avana library 4 designs)	TGAGATCCAGAAAGTCCGGACGG	KRT4	ENSG00000170477	-0.310749874865033	[]	[]	-5	hSpCas9	negative selection	3435676
52813653	52813676	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAGATCCAGAAAGTCCGGACGG	KRT4	ENSG00000170477	0.0879686343436249	[]	[]	0	hSpCas9	negative selection	3523357
52813671	52813694	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCAGGGTCAATCTCCACGTGG	KRT4	ENSG00000170477	1.31740247972398	[]	[]	1	hSpCas9	negative selection	3523358
52811845	52811868	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	-1.50264697940864	[]	[]	-2	hSpCas9	negative selection	3523359
52814003	52814026	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	3.57291978494779	[]	[]	5	hSpCas9	negative selection	3523360
52811933	52811956	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAAGGTCCTGGAGACCAAATGG	KRT4	ENSG00000170477	1.62607436677648	[]	[]	2	hSpCas9	negative selection	3523361
52813917	52813940	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CAAATCCCCCAGAAGAGCATCGG	KRT4	ENSG00000170477	0.529681306746501	[]	[]	0	hSpCas9	negative selection	3523362
52813653	52813676	12	-	26780180	A375	viability (Avana lentiGuide)	TGAGATCCAGAAAGTCCGGACGG	KRT4	ENSG00000170477	0.955957003876411	[]	[]	1	hSpCas9	negative selection	3632016
52813671	52813694	12	+	26780180	A375	viability (Avana lentiGuide)	TCTCAGGGTCAATCTCCACGTGG	KRT4	ENSG00000170477	11.8409078669658	[]	[]	7	hSpCas9	negative selection	3632017
52811845	52811868	12	+	26780180	A375	viability (Avana lentiGuide)	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	-2.61893041784818	[]	[]	-4	hSpCas9	negative selection	3632018
52814003	52814026	12	+	26780180	A375	viability (Avana lentiGuide)	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	-1.55098314413296	[]	[]	-3	hSpCas9	negative selection	3632019
52811933	52811956	12	-	26780180	A375	viability (Avana lentiGuide)	ATAAGGTCCTGGAGACCAAATGG	KRT4	ENSG00000170477	-1.70991209595593	[]	[]	-3	hSpCas9	negative selection	3632020
52813917	52813940	12	+	26780180	A375	viability (Avana lentiGuide)	CAAATCCCCCAGAAGAGCATCGG	KRT4	ENSG00000170477	-1.64696627587554	[]	[]	-3	hSpCas9	negative selection	3632021
52813653	52813676	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAGATCCAGAAAGTCCGGACGG	KRT4	ENSG00000170477	-0.23618093855398936	[6]	[4,5]	-4	hSpCas9	positive selection	3740675
52813671	52813694	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCAGGGTCAATCTCCACGTGG	KRT4	ENSG00000170477	-0.20129627178465603	[0]	[0,0]	-3	hSpCas9	positive selection	3740676
52811845	52811868	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	-0.08334381291612414	[4]	[4,3]	-1	hSpCas9	positive selection	3740677
52814003	52814026	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.3324816454800349	[4]	[4,5]	8	hSpCas9	positive selection	3740678
52811933	52811956	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAAGGTCCTGGAGACCAAATGG	KRT4	ENSG00000170477	0.11602035299735146	[5]	[5,5]	3	hSpCas9	positive selection	3740679
52813917	52813940	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAAATCCCCCAGAAGAGCATCGG	KRT4	ENSG00000170477	-0.15017390677350362	[4]	[4,3]	-2	hSpCas9	positive selection	3740680
52813653	52813676	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAGATCCAGAAAGTCCGGACGG	KRT4	ENSG00000170477	0.07264170056446109	[6]	[4,6]	1	hSpCas9	positive selection	3849282
52813671	52813694	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCAGGGTCAATCTCCACGTGG	KRT4	ENSG00000170477	-1.0086170678516093	[2]	[0,0]	-8	hSpCas9	positive selection	3849283
52811845	52811868	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.16656890422278645	[4]	[5,3]	4	hSpCas9	positive selection	3849284
52814003	52814026	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	-0.1670703392581272	[3]	[2,2]	-2	hSpCas9	positive selection	3849285
52811933	52811956	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAAGGTCCTGGAGACCAAATGG	KRT4	ENSG00000170477	-0.024622961918010833	[4]	[3,4]	0	hSpCas9	positive selection	3849286
52813917	52813940	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAAATCCCCCAGAAGAGCATCGG	KRT4	ENSG00000170477	-0.20924867393710891	[5]	[3,3]	-3	hSpCas9	positive selection	3849287
52807348	52807371	12	+	26780180	A375	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	1.70432148483921	[]	[]	9	hSpCas9	negative selection	3955364
52810767	52810790	12	-	26780180	A375	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.424689613383339	[]	[]	1	hSpCas9	negative selection	3955365
52811902	52811925	12	+	26780180	A375	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.986733146049341	[]	[]	4	hSpCas9	negative selection	3955366
52811816	52811839	12	+	26780180	A375	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.905934781773085	[]	[]	4	hSpCas9	negative selection	3955367
52811774	52811797	12	+	26780180	A375	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	1.0328868523308	[]	[]	5	hSpCas9	negative selection	3955368
52810762	52810785	12	+	26780180	A375	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	1.18279188762756	[]	[]	6	hSpCas9	negative selection	3955369
52807348	52807371	12	+	26780180	HT29	viability (GeCKOv2 library)	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.917914837570837	[]	[]	4	hSpCas9	negative selection	4063330
52810767	52810790	12	-	26780180	HT29	viability (GeCKOv2 library)	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.701485125605326	[]	[]	2	hSpCas9	negative selection	4063331
52811902	52811925	12	+	26780180	HT29	viability (GeCKOv2 library)	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.573775083017399	[]	[]	2	hSpCas9	negative selection	4063332
52811816	52811839	12	+	26780180	HT29	viability (GeCKOv2 library)	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.0551505371172189	[]	[]	0	hSpCas9	negative selection	4063333
52811774	52811797	12	+	26780180	HT29	viability (GeCKOv2 library)	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.779172913939415	[]	[]	3	hSpCas9	negative selection	4063334
52810762	52810785	12	+	26780180	HT29	viability (GeCKOv2 library)	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.590024364641925	[]	[]	2	hSpCas9	negative selection	4063335
52811852	52811875	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACCTACCTCAGTGTCCTGAGG	KRT4	ENSG00000170477	-0.4369250016939726	[3]	[1,0]	-8	hSpCas9	positive selection	4147762
52810767	52810790	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.23496103621269454	[3]	[2,3]	6	hSpCas9	positive selection	4147763
52811816	52811839	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.23894347390667098	[2]	[1,1]	-5	hSpCas9	positive selection	4147764
52810762	52810785	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.16991636088973228	[4]	[2,2]	-4	hSpCas9	positive selection	4147765
52811852	52811875	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACCTACCTCAGTGTCCTGAGG	KRT4	ENSG00000170477	0.07950757678261094	[4]	[3,2,3,0]	0	hSpCas9	positive selection	4211784
52810767	52810790	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.05407464602136272	[4]	[0,2,4,0]	0	hSpCas9	positive selection	4211785
52811816	52811839	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.8835379472797462	[3]	[1,2,0,3]	6	hSpCas9	positive selection	4211786
52810762	52810785	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.11507390602755865	[4]	[4,2,2,0]	0	hSpCas9	positive selection	4211787
52811902	52811925	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.20088112736895639	[2]	[2,0]	-4	hSpCas9	positive selection	4279179
52811816	52811839	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.031215595493459536	[1]	[1,0]	0	hSpCas9	positive selection	4279180
52810762	52810785	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.3790245609142755	[3]	[3,3]	7	hSpCas9	positive selection	4279181
52807348	52807371	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.012025140966000603	[3]	[3,1]	0	hSpCas9	positive selection	4343434
52810767	52810790	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.30048842827103195	[3]	[4,2]	6	hSpCas9	positive selection	4343435
52811774	52811797	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.18197093207497939	[2]	[3,1]	3	hSpCas9	positive selection	4343436
52808385	52808407	12	-	27760321	OCIAML3	viability	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.21795770143222984	[423,306]	[369,275]	2	hSpCas9	negative selection	4413175
52811820	52811842	12	-	27760321	OCIAML3	viability	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-2.201563343110621	[23,14]	[4,0]	-9	hSpCas9	negative selection	4413176
52813639	52813661	12	+	27760321	OCIAML3	viability	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.6560264191235052	[612,692]	[308,349]	-6	hSpCas9	negative selection	4413177
52813726	52813748	12	+	27760321	OCIAML3	viability	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.2959673376294861	[795,600]	[570,787]	3	hSpCas9	negative selection	4413178
52813760	52813782	12	-	27760321	OCIAML3	viability	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.2649884455473734	[650,573]	[498,672]	3	hSpCas9	negative selection	4413179
52808385	52808407	12	-	27760321	OCIAML2	viability	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.8806558294224065	[423,306]	[491,600]	9	hSpCas9	negative selection	4496638
52811820	52811842	12	-	27760321	OCIAML2	viability	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-3.9567775138741297	[23,14]	[0,0]	-9	hSpCas9	negative selection	4496639
52813639	52813661	12	+	27760321	OCIAML2	viability	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.26107503542159033	[612,692]	[437,452]	-3	hSpCas9	negative selection	4496640
52813726	52813748	12	+	27760321	OCIAML2	viability	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.13314577049346876	[795,600]	[460,816]	1	hSpCas9	negative selection	4496641
52813760	52813782	12	-	27760321	OCIAML2	viability	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.11611994752439253	[650,573]	[450,647]	1	hSpCas9	negative selection	4496642
52808385	52808407	12	-	27760321	MV411	viability	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.212234725557913	[423,306]	[354,158]	1	hSpCas9	negative selection	4580101
52811820	52811842	12	-	27760321	MV411	viability	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-1.5934759794837996	[23,14]	[0,8]	-7	hSpCas9	negative selection	4580102
52813639	52813661	12	+	27760321	MV411	viability	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	0.6710446932636024	[612,692]	[471,1021]	5	hSpCas9	negative selection	4580103
52813726	52813748	12	+	27760321	MV411	viability	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.22342712882696192	[795,600]	[233,983]	1	hSpCas9	negative selection	4580104
52813760	52813782	12	-	27760321	MV411	viability	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	-0.5801254828105927	[650,573]	[97,527]	-4	hSpCas9	negative selection	4580105
52808385	52808407	12	-	27760321	HL60	viability	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.4937652814339394	[423,306]	[441,388]	6	hSpCas9	negative selection	4663564
52811820	52811842	12	-	27760321	HL60	viability	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	1.6394443800151022	[23,14]	[76,18]	9	hSpCas9	negative selection	4663565
52813639	52813661	12	+	27760321	HL60	viability	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.18669203274775453	[612,692]	[623,311]	-2	hSpCas9	negative selection	4663566
52813726	52813748	12	+	27760321	HL60	viability	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.14959639165883665	[795,600]	[685,565]	1	hSpCas9	negative selection	4663567
52813760	52813782	12	-	27760321	HL60	viability	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	-0.20786255956533273	[650,573]	[494,365]	-2	hSpCas9	negative selection	4663568
52808385	52808407	12	-	27760321	HT1080	viability	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	1.637161291779776	[306,239]	[558,97]	8	hSpCas9	negative selection	4747027
52811820	52811842	12	-	27760321	HT1080	viability	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-2.429279739642115	[14,11]	[0,0]	-7	hSpCas9	negative selection	4747028
52813639	52813661	12	+	27760321	HT1080	viability	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.05726308530850388	[692,540]	[198,276]	0	hSpCas9	negative selection	4747029
52813726	52813748	12	+	27760321	HT1080	viability	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	1.206753494284139	[600,468]	[616,354]	6	hSpCas9	negative selection	4747030
52813760	52813782	12	-	27760321	HT1080	viability	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	-0.6884593645997692	[573,447]	[132,118]	-3	hSpCas9	negative selection	4747031
52808385	52808407	12	-	27760321	HT29	viability after 7 days	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	-0.3496582973216931	[306,239]	[185,265,359]	-5	hSpCas9	negative selection	4830490
52811820	52811842	12	-	27760321	HT29	viability after 7 days	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-1.7675791394741358	[14,11]	[1,11,0]	-9	hSpCas9	negative selection	4830491
52813639	52813661	12	+	27760321	HT29	viability after 7 days	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.531386141650885	[692,540]	[438,668,522]	-6	hSpCas9	negative selection	4830492
52813726	52813748	12	+	27760321	HT29	viability after 7 days	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.5563111972631755	[600,468]	[697,1173,1112]	8	hSpCas9	negative selection	4830493
52813760	52813782	12	-	27760321	HT29	viability after 7 days	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.13014835554903703	[573,447]	[710,791,653]	2	hSpCas9	negative selection	4830494
52808385	52808407	12	-	27760321	HT29	viability after 25 days	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	-0.11164794598480482	[306,239]	[225,325,322]	-1	hSpCas9	negative selection	4913953
52811820	52811842	12	-	27760321	HT29	viability after 25 days	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-1.0573353946115764	[14,11]	[0,19,0]	-6	hSpCas9	negative selection	4913954
52813639	52813661	12	+	27760321	HT29	viability after 25 days	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.6475186003689215	[692,540]	[354,487,519]	-5	hSpCas9	negative selection	4913955
52813726	52813748	12	+	27760321	HT29	viability after 25 days	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.5277745993694837	[600,468]	[831,1097,696]	6	hSpCas9	negative selection	4913956
52813760	52813782	12	-	27760321	HT29	viability after 25 days	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.08596772751723458	[573,447]	[485,407,1013]	0	hSpCas9	negative selection	4913957
52808385	52808407	12	-	27760321	HT29	viability after 22 days	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.10309986357825979	[306,239]	[202,436,382]	1	hSpCas9	negative selection	4997416
52811820	52811842	12	-	27760321	HT29	viability after 22 days	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-3.2326749107772113	[14,11]	[0,2,0]	-8	hSpCas9	negative selection	4997417
52813639	52813661	12	+	27760321	HT29	viability after 22 days	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.35515001099419485	[692,540]	[486,506,681]	-4	hSpCas9	negative selection	4997418
52813726	52813748	12	+	27760321	HT29	viability after 22 days	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.5073256110363918	[600,468]	[1179,902,542]	5	hSpCas9	negative selection	4997419
52813760	52813782	12	-	27760321	HT29	viability after 22 days	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	-0.12642780278700327	[573,447]	[391,541,694]	-1	hSpCas9	negative selection	4997420
52808385	52808407	12	-	27760321	HT29	viability after 19 days	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.1072419842410583	[306,239]	[453,367,205]	1	hSpCas9	negative selection	5080879
52811820	52811842	12	-	27760321	HT29	viability after 19 days	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-3.200568208485338	[14,11]	[0,2,0]	-9	hSpCas9	negative selection	5080880
52813639	52813661	12	+	27760321	HT29	viability after 19 days	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.3011647732602626	[692,540]	[482,669,555]	-3	hSpCas9	negative selection	5080881
52813726	52813748	12	+	27760321	HT29	viability after 19 days	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.740675189613439	[600,468]	[898,1491,675]	7	hSpCas9	negative selection	5080882
52813760	52813782	12	-	27760321	HT29	viability after 19 days	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	-0.3358543590089049	[573,447]	[579,409,412]	-3	hSpCas9	negative selection	5080883
52808385	52808407	12	-	27760321	HT29	viability after 16 days	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.43495468374207996	[306,239]	[368,406,460]	5	hSpCas9	negative selection	5164342
52811820	52811842	12	-	27760321	HT29	viability after 16 days	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	0.1701073212228188	[14,11]	[19,29,0]	1	hSpCas9	negative selection	5164343
52813639	52813661	12	+	27760321	HT29	viability after 16 days	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.6120469155996546	[692,540]	[368,415,562]	-5	hSpCas9	negative selection	5164344
52813726	52813748	12	+	27760321	HT29	viability after 16 days	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.504130019737358	[600,468]	[899,826,824]	6	hSpCas9	negative selection	5164345
52813760	52813782	12	-	27760321	HT29	viability after 16 days	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.32003452378431874	[573,447]	[675,729,730]	3	hSpCas9	negative selection	5164346
52808385	52808407	12	-	27760321	HT29	viability after 13 days	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	-0.12182460243378407	[306,239]	[230,386,258]	-1	hSpCas9	negative selection	5247805
52811820	52811842	12	-	27760321	HT29	viability after 13 days	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	0.22681753478461086	[14,11]	[0,50,3]	3	hSpCas9	negative selection	5247806
52813639	52813661	12	+	27760321	HT29	viability after 13 days	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.3498670196599238	[692,540]	[518,587,576]	-4	hSpCas9	negative selection	5247807
52813726	52813748	12	+	27760321	HT29	viability after 13 days	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.38176554847047217	[600,468]	[813,856,757]	5	hSpCas9	negative selection	5247808
52813760	52813782	12	-	27760321	HT29	viability after 13 days	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.21972349184327633	[573,447]	[858,597,617]	2	hSpCas9	negative selection	5247809
52808385	52808407	12	-	27760321	HT29	viability after 10 days	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	-0.10384051332791788	[306,239]	[267,212,465]	-1	hSpCas9	negative selection	5331268
52811820	52811842	12	-	27760321	HT29	viability after 10 days	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	1.0041819439223714	[14,11]	[18,48,33]	9	hSpCas9	negative selection	5331269
52813639	52813661	12	+	27760321	HT29	viability after 10 days	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-0.7741881436187035	[692,540]	[297,432,615]	-7	hSpCas9	negative selection	5331270
52813726	52813748	12	+	27760321	HT29	viability after 10 days	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.45548844256641174	[600,468]	[627,1250,878]	6	hSpCas9	negative selection	5331271
52813760	52813782	12	-	27760321	HT29	viability after 10 days	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.20581405228890248	[573,447]	[862,790,558]	2	hSpCas9	negative selection	5331272
52808385	52808407	12	-	27760321	MOLM13	viability	AGATCTCGGTTGACCAACATGG	KRT4	ENSG00000170477	0.36116592446136386	[423,306]	[251,270]	2	hSpCas9	negative selection	5414731
52811820	52811842	12	-	27760321	MOLM13	viability	ATACCTTGGGCAATGACAAAGG	KRT4	ENSG00000170477	-3.436896766866804	[23,14]	[0,0]	-9	hSpCas9	negative selection	5414732
52813639	52813661	12	+	27760321	MOLM13	viability	CTGTTCGCGCTCTTCCGTCCGG	KRT4	ENSG00000170477	-1.0288424470199948	[612,692]	[234,136]	-6	hSpCas9	negative selection	5414733
52813726	52813748	12	+	27760321	MOLM13	viability	CTCCTGAATTCCCCCAGCGGGG	KRT4	ENSG00000170477	0.18757087556184604	[795,600]	[449,440]	1	hSpCas9	negative selection	5414734
52813760	52813782	12	-	27760321	MOLM13	viability	TCAGTGGTAAGGGTGGCCCTGG	KRT4	ENSG00000170477	0.559417839293376	[650,573]	[436,568]	4	hSpCas9	negative selection	5414735
52811774	52811797	12	+	27661255	K562	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.3447348129975907	[351,651]	[594,425]	9	dCas9-KRAB	negative selection	5489308
52814003	52814026	12	+	27661255	K562	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	-0.06906061491889073	[662,953]	[656,572]	-3	dCas9-KRAB	negative selection	5489309
52814029	52814052	12	+	27661255	K562	viability	GCCTCGGACACACTGCTGTCTGG	KRT4	ENSG00000170477	-0.04434079501726726	[904,903]	[853,569]	-2	dCas9-KRAB	negative selection	5489310
52811649	52811672	12	-	27661255	K562	viability	GGCTCTGAAGGCGTCTAGGAAGG	KRT4	ENSG00000170477	-0.004977767657595944	[357,487]	[329,338]	0	dCas9-KRAB	negative selection	5489311
52811776	52811799	12	-	27661255	K562	viability	GACCATGCAGGACAGCGTGGAGG	KRT4	ENSG00000170477	0.16184742967994403	[380,437]	[357,370]	5	dCas9-KRAB	negative selection	5489312
52813888	52813911	12	-	27661255	K562	viability	GAAGCCTCTACAACCTCAGGGGG	KRT4	ENSG00000170477	0.3981137029643862	[126,101]	[120,120]	9	dCas9-KRAB	negative selection	5489313
52814102	52814125	12	-	27661255	K562	viability	GCTCCAGCACTCACCGGCCTGGG	KRT4	ENSG00000170477	0.1538443313540614	[345,429]	[370,319]	5	dCas9-KRAB	negative selection	5489314
52811902	52811925	12	+	27260156	BXPC3	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.16547254883414486	[329]	[260,287,337,353]	-4	hSpCas9	negative selection	5551639
52811816	52811839	12	+	27260156	BXPC3	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.4830266785532942	[156]	[225,206,249,235]	8	hSpCas9	negative selection	5551640
52810762	52810785	12	+	27260156	BXPC3	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.0641126105226204	[602]	[648,648,666,669]	1	hSpCas9	negative selection	5551641
52807348	52807371	12	+	27260156	BXPC3	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.07707830776704075	[546]	[478,622,614,718]	1	hSpCas9	negative selection	5615894
52810767	52810790	12	-	27260156	BXPC3	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.014580166843236597	[684]	[702,683,643,813]	0	hSpCas9	negative selection	5615895
52811774	52811797	12	+	27260156	BXPC3	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.40544042209746234	[349]	[442,521,460,514]	8	hSpCas9	negative selection	5615896
52811902	52811925	12	+	27260156	A673	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.24318592928611588	[329]	[563,453,370,499]	6	hSpCas9	negative selection	5672890
52811816	52811839	12	+	27260156	A673	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.37626807215530733	[156]	[289,250,208,232]	8	hSpCas9	negative selection	5672891
52810762	52810785	12	+	27260156	A673	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.033629047608958074	[602]	[864,587,710,683]	-1	hSpCas9	negative selection	5672892
52807348	52807371	12	+	27260156	A673	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.26681193390770014	[546]	[562,540,588,487]	-6	hSpCas9	negative selection	5737145
52810767	52810790	12	-	27260156	A673	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.007348769951927014	[684]	[881,728,928,769]	0	hSpCas9	negative selection	5737146
52811774	52811797	12	+	27260156	A673	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.2731398228132129	[349]	[452,459,609,500]	6	hSpCas9	negative selection	5737147
52811902	52811925	12	+	27260156	A375	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.21140960091675437	[329]	[441,628,321,418]	3	hSpCas9	negative selection	5794141
52811816	52811839	12	+	27260156	A375	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.03559076209954948	[156]	[173,93,254,211]	0	hSpCas9	negative selection	5794142
52810762	52810785	12	+	27260156	A375	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.13361057525351733	[602]	[837,805,669,777]	2	hSpCas9	negative selection	5794143
52807348	52807371	12	+	27260156	A375	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.04487613220406958	[546]	[628,703,573,583]	0	hSpCas9	negative selection	5858396
52810767	52810790	12	-	27260156	A375	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.3490743048541154	[684]	[1048,1168,990,898]	5	hSpCas9	negative selection	5858397
52811774	52811797	12	+	27260156	A375	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.1436317232112614	[349]	[382,539,428,462]	2	hSpCas9	negative selection	5858398
52811902	52811925	12	+	27260156	COLO741	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.07444730052552051	[329]	[371,382,439]	-2	hSpCas9	negative selection	5915392
52811816	52811839	12	+	27260156	COLO741	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	1.1408870867161842	[156]	[503,465,366]	9	hSpCas9	negative selection	5915393
52810762	52810785	12	+	27260156	COLO741	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.15301367256517784	[602]	[1286,631,696]	3	hSpCas9	negative selection	5915394
52807348	52807371	12	+	27260156	COLO741	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.17369089110980387	[546]	[692,556,613]	-4	hSpCas9	negative selection	5979647
52810767	52810790	12	-	27260156	COLO741	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.19972055823138357	[684]	[1007,630,1347]	4	hSpCas9	negative selection	5979648
52811774	52811797	12	+	27260156	COLO741	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.1522879016159353	[349]	[474,473,535]	3	hSpCas9	negative selection	5979649
52811902	52811925	12	+	27260156	CAL120	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.05408034259137551	[329]	[361,456,362]	-1	hSpCas9	negative selection	6036643
52811816	52811839	12	+	27260156	CAL120	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	1.0829001101537106	[156]	[350,359,518]	9	hSpCas9	negative selection	6036644
52810762	52810785	12	+	27260156	CAL120	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.13371815941046866	[602]	[957,630,506]	-2	hSpCas9	negative selection	6036645
52807348	52807371	12	+	27260156	CAL120	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.6117303608968538	[546]	[317,554,443]	-7	hSpCas9	negative selection	6100898
52810767	52810790	12	-	27260156	CAL120	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.07645877000326617	[684]	[1406,774,595]	1	hSpCas9	negative selection	6100899
52811774	52811797	12	+	27260156	CAL120	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	-0.30101095676210693	[349]	[390,374,300]	-4	hSpCas9	negative selection	6100900
52811902	52811925	12	+	27260156	CADOES1	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.003854561613014895	[329]	[370,246,423,183]	0	hSpCas9	negative selection	6157894
52811816	52811839	12	+	27260156	CADOES1	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.4762130449172679	[156]	[216,205,172,216]	7	hSpCas9	negative selection	6157895
52810762	52810785	12	+	27260156	CADOES1	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.3467295305040592	[602]	[543,869,789,646]	6	hSpCas9	negative selection	6157896
52807348	52807371	12	+	27260156	CADOES1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.09815164119346968	[546]	[502,434,384,581]	-2	hSpCas9	negative selection	6222149
52810767	52810790	12	-	27260156	CADOES1	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.182294544767877	[684]	[608,776,807,696]	3	hSpCas9	negative selection	6222150
52811774	52811797	12	+	27260156	CADOES1	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.172768647100571	[349]	[498,344,265,356]	3	hSpCas9	negative selection	6222151
52811902	52811925	12	+	27260156	EWS502	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.17054108971416604	[329]	[296,354,171,422]	-3	hSpCas9	negative selection	6279145
52811816	52811839	12	+	27260156	EWS502	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.5095690081089361	[156]	[163,242,273,276]	8	hSpCas9	negative selection	6279146
52810762	52810785	12	+	27260156	EWS502	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.18296764570923774	[602]	[450,894,781,801]	3	hSpCas9	negative selection	6279147
52807348	52807371	12	+	27260156	EWS502	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.2034135556676696	[546]	[448,383,700,489]	-4	hSpCas9	negative selection	6343400
52810767	52810790	12	-	27260156	EWS502	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.055281821340078086	[684]	[651,808,831,728]	0	hSpCas9	negative selection	6343401
52811774	52811797	12	+	27260156	EWS502	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.3231982573912724	[349]	[331,496,457,589]	5	hSpCas9	negative selection	6343402
52811902	52811925	12	+	27260156	EW8	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.0008408658479978071	[329]	[250,269,253,294]	0	hSpCas9	negative selection	6400396
52811816	52811839	12	+	27260156	EW8	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.429812215721471	[156]	[207,157,183,136]	7	hSpCas9	negative selection	6400397
52810762	52810785	12	+	27260156	EW8	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.2588772420978003	[602]	[677,408,568,692]	5	hSpCas9	negative selection	6400398
52807348	52807371	12	+	27260156	EW8	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.3224627677114697	[546]	[456,421,306,250]	-6	hSpCas9	negative selection	6464651
52810767	52810790	12	-	27260156	EW8	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.09783756765757012	[684]	[725,763,556,349]	1	hSpCas9	negative selection	6464652
52811774	52811797	12	+	27260156	EW8	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	-0.1700239094316532	[349]	[392,212,175,253]	-3	hSpCas9	negative selection	6464653
52811902	52811925	12	+	27260156	CORL105	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.19912030443578665	[329]	[340,331,328,342]	-4	hSpCas9	negative selection	6521647
52811816	52811839	12	+	27260156	CORL105	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.7619945447396025	[156]	[211,343,440,265]	9	hSpCas9	negative selection	6521648
52810762	52810785	12	+	27260156	CORL105	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.39873951638183025	[602]	[985,916,1082,762]	7	hSpCas9	negative selection	6521649
52807348	52807371	12	+	27260156	CORL105	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.2155992432558066	[546]	[571,476,534,620]	-4	hSpCas9	negative selection	6585902
52810767	52810790	12	-	27260156	CORL105	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.08970042316520632	[684]	[851,727,896,944]	1	hSpCas9	negative selection	6585903
52811774	52811797	12	+	27260156	CORL105	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.1735843148194715	[349]	[484,443,483,439]	3	hSpCas9	negative selection	6585904
52811902	52811925	12	+	27260156	HS294T	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.19310426726982594	[329]	[137,90,163,201]	2	hSpCas9	negative selection	6642898
52811816	52811839	12	+	27260156	HS294T	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.394393303515415	[156]	[134,46,65,63]	5	hSpCas9	negative selection	6642899
52810762	52810785	12	+	27260156	HS294T	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.6573255825717554	[602]	[335,326,468,336]	8	hSpCas9	negative selection	6642900
52807348	52807371	12	+	27260156	HS294T	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.35743545694183027	[546]	[126,125,185,237]	-5	hSpCas9	negative selection	6707153
52810767	52810790	12	-	27260156	HS294T	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.18058733958572393	[684]	[315,283,296,301]	2	hSpCas9	negative selection	6707154
52811774	52811797	12	+	27260156	HS294T	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.5193760290861351	[349]	[162,181,252,177]	7	hSpCas9	negative selection	6707155
52811902	52811925	12	+	27260156	HCC44	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.2414763130674179	[329]	[341,223,354,359]	-4	hSpCas9	negative selection	6764149
52811816	52811839	12	+	27260156	HCC44	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.47517526645492936	[156]	[310,310,174,174]	7	hSpCas9	negative selection	6764150
52810762	52810785	12	+	27260156	HCC44	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.045577904347175346	[602]	[662,644,677,819]	0	hSpCas9	negative selection	6764151
52807348	52807371	12	+	27260156	HCC44	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.11523134672247452	[546]	[641,513,637,513]	-2	hSpCas9	negative selection	6828404
52810767	52810790	12	-	27260156	HCC44	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.18153871136286825	[684]	[1020,833,916,764]	3	hSpCas9	negative selection	6828405
52811774	52811797	12	+	27260156	HCC44	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	-0.007389943511961983	[349]	[686,198,402,340]	0	hSpCas9	negative selection	6828406
52811902	52811925	12	+	27260156	G402	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.01026662887955121	[329]	[472,542,357,249]	0	hSpCas9	negative selection	6885400
52811816	52811839	12	+	27260156	G402	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.8801191540156295	[156]	[211,497,394,294]	9	hSpCas9	negative selection	6885401
52810762	52810785	12	+	27260156	G402	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.35678439469953716	[602]	[604,1129,1019,970]	4	hSpCas9	negative selection	6885402
52807348	52807371	12	+	27260156	G402	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.01742123910808077	[546]	[608,806,634,647]	0	hSpCas9	negative selection	6949655
52810767	52810790	12	-	27260156	G402	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.21439775127789334	[684]	[801,703,775,612]	-3	hSpCas9	negative selection	6949656
52811774	52811797	12	+	27260156	G402	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.49331622769768846	[349]	[1116,245,550,544]	6	hSpCas9	negative selection	6949657
52811902	52811925	12	+	27260156	L33	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.3955183200822432	[329]	[228,116,138,267]	-7	hSpCas9	negative selection	7006651
52811816	52811839	12	+	27260156	L33	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.6693130563591313	[156]	[220,98,180,248]	9	hSpCas9	negative selection	7006652
52810762	52810785	12	+	27260156	L33	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.37464023910525757	[602]	[775,312,562,692]	7	hSpCas9	negative selection	7006653
52807348	52807371	12	+	27260156	L33	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.4887587779402538	[546]	[379,169,279,319]	-8	hSpCas9	negative selection	7070906
52810767	52810790	12	-	27260156	L33	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.08284172145122759	[684]	[516,268,392,789]	-2	hSpCas9	negative selection	7070907
52811774	52811797	12	+	27260156	L33	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.3590285132662775	[349]	[486,175,282,427]	7	hSpCas9	negative selection	7070908
52811902	52811925	12	+	27260156	K562	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.13918446586684396	[329]	[343,326,265,148]	-2	hSpCas9	negative selection	7127902
52811816	52811839	12	+	27260156	K562	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.4614489389971368	[156]	[272,104,173,213]	6	hSpCas9	negative selection	7127903
52810762	52810785	12	+	27260156	K562	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.48325349884005797	[602]	[591,1311,798,349]	6	hSpCas9	negative selection	7127904
52807348	52807371	12	+	27260156	K562	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.3576562711565804	[546]	[548,568,128,299]	-4	hSpCas9	negative selection	7192157
52810767	52810790	12	-	27260156	K562	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.2261013462703706	[684]	[538,690,1026,583]	3	hSpCas9	negative selection	7192158
52811774	52811797	12	+	27260156	K562	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.1303502703588868	[349]	[356,317,327,353]	1	hSpCas9	negative selection	7192159
52811902	52811925	12	+	27260156	HT29	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.19210034265066744	[329]	[355,376,368,307]	-4	hSpCas9	negative selection	7249153
52811816	52811839	12	+	27260156	HT29	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.4791342492806594	[156]	[214,197,270,356]	8	hSpCas9	negative selection	7249154
52810762	52810785	12	+	27260156	HT29	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.08447478315832718	[602]	[923,881,894,461]	1	hSpCas9	negative selection	7249155
52807348	52807371	12	+	27260156	HT29	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.053483836417163505	[546]	[665,785,775,550]	1	hSpCas9	negative selection	7313408
52810767	52810790	12	-	27260156	HT29	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.1991267520625435	[684]	[1193,1027,1037,622]	4	hSpCas9	negative selection	7313409
52811774	52811797	12	+	27260156	HT29	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.23766100198789755	[349]	[721,340,592,366]	4	hSpCas9	negative selection	7313410
52811902	52811925	12	+	27260156	MHHES1	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.01181797308774385	[329]	[421,353,415,315]	0	hSpCas9	negative selection	7370404
52811816	52811839	12	+	27260156	MHHES1	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.5702570730744339	[156]	[313,343,249,171]	8	hSpCas9	negative selection	7370405
52810762	52810785	12	+	27260156	MHHES1	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.3858252300754469	[602]	[839,982,1199,583]	7	hSpCas9	negative selection	7370406
52807348	52807371	12	+	27260156	MHHES1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.2646838628271594	[546]	[767,529,546,281]	-5	hSpCas9	negative selection	7434659
52810767	52810790	12	-	27260156	MHHES1	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.2913383518914281	[684]	[1523,959,573,799]	5	hSpCas9	negative selection	7434660
52811774	52811797	12	+	27260156	MHHES1	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.12250419641723137	[349]	[531,253,503,414]	2	hSpCas9	negative selection	7434661
52811902	52811925	12	+	27260156	MEWO	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.024969358006056763	[329]	[443,204,318]	0	hSpCas9	negative selection	7491655
52811816	52811839	12	+	27260156	MEWO	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.6184549725676873	[156]	[293,167,227]	9	hSpCas9	negative selection	7491656
52810762	52810785	12	+	27260156	MEWO	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.09483654791850227	[602]	[612,539,447]	-2	hSpCas9	negative selection	7491657
52807348	52807371	12	+	27260156	MEWO	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.24835131136967967	[546]	[480,449,370]	-5	hSpCas9	negative selection	7555910
52810767	52810790	12	-	27260156	MEWO	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.1486618484133262	[684]	[657,512,578]	-3	hSpCas9	negative selection	7555911
52811774	52811797	12	+	27260156	MEWO	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.15127326290554216	[349]	[353,360,373]	3	hSpCas9	negative selection	7555912
52811902	52811925	12	+	27260156	LNCAPCLONEFGC	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.23476312176070224	[329]	[296,224,293,206]	-4	hSpCas9	negative selection	7612906
52811816	52811839	12	+	27260156	LNCAPCLONEFGC	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.416372560300164	[156]	[176,141,199,244]	6	hSpCas9	negative selection	7612907
52810762	52810785	12	+	27260156	LNCAPCLONEFGC	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.32390426196518807	[602]	[595,613,954,615]	5	hSpCas9	negative selection	7612908
52807348	52807371	12	+	27260156	LNCAPCLONEFGC	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.45917322185988685	[546]	[342,357,427,322]	-6	hSpCas9	negative selection	7677161
52810767	52810790	12	-	27260156	LNCAPCLONEFGC	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.1909283515811805	[684]	[748,669,805,623]	3	hSpCas9	negative selection	7677162
52811774	52811797	12	+	27260156	LNCAPCLONEFGC	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.48390912566174776	[349]	[330,518,493,433]	7	hSpCas9	negative selection	7677163
52811902	52811925	12	+	27260156	PANC0327	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.43021219887723894	[329]	[182,250,212,215]	-6	hSpCas9	negative selection	7734157
52811816	52811839	12	+	27260156	PANC0327	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.38223921078704803	[156]	[107,213,263,130]	5	hSpCas9	negative selection	7734158
52810762	52810785	12	+	27260156	PANC0327	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.3163366192782707	[602]	[431,453,831,957]	5	hSpCas9	negative selection	7734159
52807348	52807371	12	+	27260156	PANC0327	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.6125156151021329	[546]	[317,302,294,356]	-7	hSpCas9	negative selection	7798412
52810767	52810790	12	-	27260156	PANC0327	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.4152590654751709	[684]	[708,1180,960,338]	6	hSpCas9	negative selection	7798413
52811774	52811797	12	+	27260156	PANC0327	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.13391705537958026	[349]	[428,271,498,180]	2	hSpCas9	negative selection	7798414
52811902	52811925	12	+	27260156	NCIH2009	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.2960281674251425	[329]	[754,488,491]	4	hSpCas9	negative selection	7855408
52811816	52811839	12	+	27260156	NCIH2009	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.7389573466702147	[156]	[446,346,319]	8	hSpCas9	negative selection	7855409
52810762	52810785	12	+	27260156	NCIH2009	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.6778363116776802	[602]	[1651,1188,1262]	8	hSpCas9	negative selection	7855410
52807348	52807371	12	+	27260156	NCIH2009	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.3300967854010137	[546]	[595,576,647]	-4	hSpCas9	negative selection	7919663
52810767	52810790	12	-	27260156	NCIH2009	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.058103308494751205	[684]	[969,1119,889]	0	hSpCas9	negative selection	7919664
52811774	52811797	12	+	27260156	NCIH2009	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.6983729648432415	[349]	[857,566,970]	8	hSpCas9	negative selection	7919665
52811902	52811925	12	+	27260156	NCIH1373	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.14998284935746387	[329]	[735,157,292,57]	-1	hSpCas9	negative selection	7976659
52811816	52811839	12	+	27260156	NCIH1373	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.03274750859964182	[156]	[105,368,77,34]	0	hSpCas9	negative selection	7976660
52810762	52810785	12	+	27260156	NCIH1373	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.044282244678137794	[602]	[658,650,795,176]	0	hSpCas9	negative selection	7976661
52807348	52807371	12	+	27260156	NCIH1373	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-1.601322634015424	[546]	[165,128,292,57]	-9	hSpCas9	negative selection	8040914
52810767	52810790	12	-	27260156	NCIH1373	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.06617946783813655	[684]	[1044,686,734,208]	0	hSpCas9	negative selection	8040915
52811774	52811797	12	+	27260156	NCIH1373	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.5254476387688382	[349]	[461,558,765,115]	5	hSpCas9	negative selection	8040916
52811902	52811925	12	+	27260156	PATU8902	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.33524811914950503	[329]	[659,803,294,635]	3	hSpCas9	negative selection	8097910
52811816	52811839	12	+	27260156	PATU8902	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.08622743475631678	[156]	[249,64,198,322]	-1	hSpCas9	negative selection	8097911
52810762	52810785	12	+	27260156	PATU8902	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.7395938244180766	[602]	[888,473,309,362]	-6	hSpCas9	negative selection	8097912
52807348	52807371	12	+	27260156	PATU8902	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.15107050583031842	[546]	[887,748,688,1123]	1	hSpCas9	negative selection	8162165
52810767	52810790	12	-	27260156	PATU8902	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.13195908838433779	[684]	[1313,941,583,1503]	1	hSpCas9	negative selection	8162166
52811774	52811797	12	+	27260156	PATU8902	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.48573484523042515	[349]	[838,569,564,791]	5	hSpCas9	negative selection	8162167
52811902	52811925	12	+	27260156	PANC1	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.5612765237543326	[329]	[164,256,198,162]	-7	hSpCas9	negative selection	8219161
52811816	52811839	12	+	27260156	PANC1	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.3516711592906834	[156]	[127,294,200,99]	5	hSpCas9	negative selection	8219162
52810762	52810785	12	+	27260156	PANC1	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.2722406986928949	[602]	[555,792,606,578]	4	hSpCas9	negative selection	8219163
52807348	52807371	12	+	27260156	PANC1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.10732379283098925	[546]	[518,566,326,360]	-2	hSpCas9	negative selection	8283416
52810767	52810790	12	-	27260156	PANC1	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.4044408751124784	[684]	[1049,913,646,549]	6	hSpCas9	negative selection	8283417
52811774	52811797	12	+	27260156	PANC1	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.3767221550067654	[349]	[407,398,372,377]	6	hSpCas9	negative selection	8283418
52811902	52811925	12	+	27260156	PANC0813	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.2500581810475939	[329]	[422,348,253,287]	-4	hSpCas9	negative selection	8340412
52811816	52811839	12	+	27260156	PANC0813	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.4378133947638283	[156]	[245,363,157,230]	7	hSpCas9	negative selection	8340413
52810762	52810785	12	+	27260156	PANC0813	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.38589185631573664	[602]	[1023,862,835,982]	6	hSpCas9	negative selection	8340414
52807348	52807371	12	+	27260156	PANC0813	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.32101246919763793	[546]	[554,505,584,419]	-5	hSpCas9	negative selection	8404667
52810767	52810790	12	-	27260156	PANC0813	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.11467351350880378	[684]	[786,613,815,757]	-2	hSpCas9	negative selection	8404668
52811774	52811797	12	+	27260156	PANC0813	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.15070965574408407	[349]	[469,564,343,446]	2	hSpCas9	negative selection	8404669
52811902	52811925	12	+	27260156	RDES	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.4752509155134136	[329]	[182,257,286,396]	-7	hSpCas9	negative selection	8461663
52811816	52811839	12	+	27260156	RDES	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.06575039206702815	[156]	[200,194,105,249]	1	hSpCas9	negative selection	8461664
52810762	52810785	12	+	27260156	RDES	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.23133191356344393	[602]	[470,463,607,886]	-4	hSpCas9	negative selection	8461665
52807348	52807371	12	+	27260156	RDES	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.8282078564589989	[546]	[229,448,400,344]	-8	hSpCas9	negative selection	8525918
52810767	52810790	12	-	27260156	RDES	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.0052163708548037535	[684]	[616,625,961,1003]	0	hSpCas9	negative selection	8525919
52811774	52811797	12	+	27260156	RDES	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.20996199477055313	[349]	[426,358,561,531]	3	hSpCas9	negative selection	8525920
52811902	52811925	12	+	27260156	PC3	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.042309036130433575	[329]	[197,337,464,355]	-1	hSpCas9	negative selection	8582914
52811816	52811839	12	+	27260156	PC3	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.8336722969958901	[156]	[180,202,644,247]	9	hSpCas9	negative selection	8582915
52810762	52810785	12	+	27260156	PC3	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.3020323577617837	[602]	[394,808,1479,648]	6	hSpCas9	negative selection	8582916
52807348	52807371	12	+	27260156	PC3	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.18328427969817923	[546]	[256,563,654,567]	-4	hSpCas9	negative selection	8647169
52810767	52810790	12	-	27260156	PC3	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.31070354853967697	[684]	[493,876,1537,821]	6	hSpCas9	negative selection	8647170
52811774	52811797	12	+	27260156	PC3	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.3926414837322511	[349]	[286,378,1002,408]	7	hSpCas9	negative selection	8647171
52811902	52811925	12	+	27260156	PATU8988T	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.09876916891167342	[329]	[384,434,223,148]	-2	hSpCas9	negative selection	8704165
52811816	52811839	12	+	27260156	PATU8988T	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.9648905988092658	[156]	[467,395,89,237]	9	hSpCas9	negative selection	8704166
52810762	52810785	12	+	27260156	PATU8988T	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.20853980427060337	[602]	[724,721,665,576]	3	hSpCas9	negative selection	8704167
52807348	52807371	12	+	27260156	PATU8988T	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.002445533147627743	[546]	[707,460,501,432]	0	hSpCas9	negative selection	8768420
52810767	52810790	12	-	27260156	PATU8988T	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.09022284029464228	[684]	[683,636,668,486]	-1	hSpCas9	negative selection	8768421
52811774	52811797	12	+	27260156	PATU8988T	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.123752885347851	[349]	[347,361,305,465]	2	hSpCas9	negative selection	8768422
52811902	52811925	12	+	27260156	T47D	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.0234454969304837	[329]	[424,352,339,450]	0	hSpCas9	negative selection	8825416
52811816	52811839	12	+	27260156	T47D	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.5101767993456083	[156]	[300,274,238,224]	9	hSpCas9	negative selection	8825417
52810762	52810785	12	+	27260156	T47D	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.0035698888841637078	[602]	[659,685,674,785]	0	hSpCas9	negative selection	8825418
52807348	52807371	12	+	27260156	T47D	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.23772472960557803	[546]	[521,562,566,505]	-5	hSpCas9	negative selection	8889671
52810767	52810790	12	-	27260156	T47D	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.05073766179296202	[684]	[750,831,897,822]	1	hSpCas9	negative selection	8889672
52811774	52811797	12	+	27260156	T47D	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.1453411583865789	[349]	[480,490,448,376]	3	hSpCas9	negative selection	8889673
52811902	52811925	12	+	27260156	SU8686	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.065182517720209	[329]	[367,217,361,306]	-1	hSpCas9	negative selection	8946667
52811816	52811839	12	+	27260156	SU8686	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.4866141417228065	[156]	[150,238,219,274]	7	hSpCas9	negative selection	8946668
52810762	52810785	12	+	27260156	SU8686	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.3111915257209562	[602]	[696,817,731,702]	5	hSpCas9	negative selection	8946669
52807348	52807371	12	+	27260156	SU8686	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.6467747163607547	[546]	[349,280,377,389]	-7	hSpCas9	negative selection	9010922
52810767	52810790	12	-	27260156	SU8686	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.09503384886540878	[684]	[652,651,840,779]	1	hSpCas9	negative selection	9010923
52811774	52811797	12	+	27260156	SU8686	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.3447346406756303	[349]	[391,389,474,529]	6	hSpCas9	negative selection	9010924
52811902	52811925	12	+	27260156	SKES1	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.32067846462407834	[329]	[217,308,304,222]	-6	hSpCas9	negative selection	9067918
52811816	52811839	12	+	27260156	SKES1	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.40987227815856575	[156]	[261,232,174,174]	8	hSpCas9	negative selection	9067919
52810762	52810785	12	+	27260156	SKES1	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.06538655868136345	[602]	[751,567,568,631]	1	hSpCas9	negative selection	9067920
52807348	52807371	12	+	27260156	SKES1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.4020882037197815	[546]	[511,370,550,240]	-7	hSpCas9	negative selection	9132173
52810767	52810790	12	-	27260156	SKES1	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.12535831620069482	[684]	[795,662,804,709]	2	hSpCas9	negative selection	9132174
52811774	52811797	12	+	27260156	SKES1	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.47094438430270724	[349]	[462,576,522,386]	8	hSpCas9	negative selection	9132175
52811902	52811925	12	+	27260156	TOV112D	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.29235316714191983	[329]	[489,419,412,308]	5	hSpCas9	negative selection	9189169
52811816	52811839	12	+	27260156	TOV112D	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.3446984339337247	[156]	[191,319,138,176]	6	hSpCas9	negative selection	9189170
52810762	52810785	12	+	27260156	TOV112D	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.02338681033408463	[602]	[693,826,485,438]	0	hSpCas9	negative selection	9189171
52807348	52807371	12	+	27260156	TOV112D	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.2008000274778836	[546]	[545,506,346,517]	-4	hSpCas9	negative selection	9253424
52810767	52810790	12	-	27260156	TOV112D	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.2342972782268673	[684]	[687,666,518,489]	-4	hSpCas9	negative selection	9253425
52811774	52811797	12	+	27260156	TOV112D	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	-0.2085350299361805	[349]	[325,320,333,239]	-4	hSpCas9	negative selection	9253426
52811902	52811925	12	+	27260156	TC71	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	-0.23309711391488963	[329]	[250,282,255,423]	-6	hSpCas9	negative selection	9310420
52811816	52811839	12	+	27260156	TC71	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.6142189069968853	[156]	[270,226,259,272]	9	hSpCas9	negative selection	9310421
52810762	52810785	12	+	27260156	TC71	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	0.14841542839185162	[602]	[653,695,810,701]	4	hSpCas9	negative selection	9310422
52807348	52807371	12	+	27260156	TC71	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.14082512010526077	[546]	[535,505,586,493]	-4	hSpCas9	negative selection	9374675
52810767	52810790	12	-	27260156	TC71	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	-0.1212598021320081	[684]	[656,759,558,731]	-3	hSpCas9	negative selection	9374676
52811774	52811797	12	+	27260156	TC71	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	-0.10872032410278992	[349]	[294,331,382,383]	-3	hSpCas9	negative selection	9374677
52811902	52811925	12	+	27260156	TC32	viability	AGGTGGTGGTCGTCTGCTGCTGG	KRT4	ENSG00000170477	0.022684030638583763	[329]	[223,222,477,396]	0	hSpCas9	negative selection	9431671
52811816	52811839	12	+	27260156	TC32	viability	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.37959841532827476	[156]	[150,126,308,221]	6	hSpCas9	negative selection	9431672
52810762	52810785	12	+	27260156	TC32	viability	TAGGACCACAAAGTCATTCTCGG	KRT4	ENSG00000170477	-0.03577568459862818	[602]	[357,464,709,741]	0	hSpCas9	negative selection	9431673
52807348	52807371	12	+	27260156	TC32	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.20883565302656282	[546]	[354,251,698,585]	-4	hSpCas9	negative selection	9495926
52810767	52810790	12	-	27260156	TC32	viability	AGCAGCCGAGAATGACTTTGTGG	KRT4	ENSG00000170477	0.23890290789914925	[684]	[559,852,881,700]	4	hSpCas9	negative selection	9495927
52811774	52811797	12	+	27260156	TC32	viability	GTCCTCCACGCTGTCCTGCATGG	KRT4	ENSG00000170477	0.1926184491986132	[349]	[335,337,506,338]	3	hSpCas9	negative selection	9495928
52807208	52807231	12	-	27869803	HPAFII	viability after 27 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.9737972028552514	[376]	[475,316,NaN]	7	hSpCas9	negative selection	9547297
52807777	52807800	12	-	27869803	HPAFII	viability after 27 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.3563158033841074	[242]	[78,233,NaN]	3	hSpCas9	negative selection	9547298
52808808	52808831	12	+	27869803	HPAFII	viability after 27 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.5166787296660648	[284]	[131,282,NaN]	4	hSpCas9	negative selection	9547299
52811816	52811839	12	+	27869803	HPAFII	viability after 27 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	-0.1321390813117111	[277]	[194,81,NaN]	-1	hSpCas9	negative selection	9547300
52813978	52814001	12	+	27869803	HPAFII	viability after 27 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.09369887038828129	[367]	[194,215,NaN]	0	hSpCas9	negative selection	9547301
52814131	52814154	12	-	27869803	HPAFII	viability after 27 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.3543129787094062	[377]	[77,219,NaN]	-3	hSpCas9	negative selection	9547302
52807208	52807231	12	-	27869803	HPAFII	viability after 15 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.4327363905730327	[376]	[713,442,NaN]	5	hSpCas9	negative selection	9629746
52807777	52807800	12	-	27869803	HPAFII	viability after 15 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	-0.17578037994256238	[242]	[245,221,NaN]	-2	hSpCas9	negative selection	9629747
52808808	52808831	12	+	27869803	HPAFII	viability after 15 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-0.030084160222742323	[284]	[233,340,NaN]	0	hSpCas9	negative selection	9629748
52811816	52811839	12	+	27869803	HPAFII	viability after 15 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.36070567676578746	[277]	[485,319,NaN]	4	hSpCas9	negative selection	9629749
52813978	52814001	12	+	27869803	HPAFII	viability after 15 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.03178524127821125	[367]	[518,332,NaN]	0	hSpCas9	negative selection	9629750
52814131	52814154	12	-	27869803	HPAFII	viability after 15 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.35939013931718744	[377]	[328,308,NaN]	-4	hSpCas9	negative selection	9629751
52807208	52807231	12	-	27869803	ASPC1	viability after 36 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.008698445296230983	[1043]	[225,210,584]	0	hSpCas9	negative selection	9712195
52807777	52807800	12	-	27869803	ASPC1	viability after 36 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	-0.4919404460870308	[616]	[162,226,85]	-5	hSpCas9	negative selection	9712196
52808808	52808831	12	+	27869803	ASPC1	viability after 36 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.1518984154392405	[786]	[272,174,427]	1	hSpCas9	negative selection	9712197
52811816	52811839	12	+	27869803	ASPC1	viability after 36 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.3538224977339209	[782]	[272,482,292]	3	hSpCas9	negative selection	9712198
52813978	52814001	12	+	27869803	ASPC1	viability after 36 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	1.2810145600291862	[841]	[933,520,705]	9	hSpCas9	negative selection	9712199
52814131	52814154	12	-	27869803	ASPC1	viability after 36 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	0.3394757802432246	[732]	[424,75,445]	3	hSpCas9	negative selection	9712200
52807208	52807231	12	-	27869803	PATU8988S	viability after 35 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.36734278505788315	[893]	[331,225,NaN]	-4	hSpCas9	negative selection	9794644
52807777	52807800	12	-	27869803	PATU8988S	viability after 35 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.41011084020547567	[511]	[276,270,NaN]	4	hSpCas9	negative selection	9794645
52808808	52808831	12	+	27869803	PATU8988S	viability after 35 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.07759743328803853	[766]	[316,334,NaN]	0	hSpCas9	negative selection	9794646
52811816	52811839	12	+	27869803	PATU8988S	viability after 35 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.32821487182099096	[857]	[361,505,NaN]	4	hSpCas9	negative selection	9794647
52813978	52814001	12	+	27869803	PATU8988S	viability after 35 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.6737642739314725	[661]	[346,503,NaN]	7	hSpCas9	negative selection	9794648
52814131	52814154	12	-	27869803	PATU8988S	viability after 35 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.24117302250018569	[605]	[203,208,NaN]	-3	hSpCas9	negative selection	9794649
52807208	52807231	12	-	27869803	PATU8988S	viability after 31 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	-0.7194783916827686	[893]	[285,127,NaN]	-6	hSpCas9	negative selection	9877093
52807777	52807800	12	-	27869803	PATU8988S	viability after 31 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.419200365743487	[511]	[250,300,NaN]	5	hSpCas9	negative selection	9877094
52808808	52808831	12	+	27869803	PATU8988S	viability after 31 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	-0.1205951753597817	[766]	[235,338,NaN]	-1	hSpCas9	negative selection	9877095
52811816	52811839	12	+	27869803	PATU8988S	viability after 31 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.1701695375514336	[857]	[347,431,NaN]	2	hSpCas9	negative selection	9877096
52813978	52814001	12	+	27869803	PATU8988S	viability after 31 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.4308146540497235	[661]	[295,431,NaN]	5	hSpCas9	negative selection	9877097
52814131	52814154	12	-	27869803	PATU8988S	viability after 31 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.32360578524323724	[605]	[222,154,NaN]	-4	hSpCas9	negative selection	9877098
52807208	52807231	12	-	27869803	HPAFII	viability after 35 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	1.2441621632449515	[376]	[413,494,NaN]	8	hSpCas9	negative selection	9959542
52807777	52807800	12	-	27869803	HPAFII	viability after 35 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.17190314662945907	[242]	[12,279,NaN]	1	hSpCas9	negative selection	9959543
52808808	52808831	12	+	27869803	HPAFII	viability after 35 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.5285597816215656	[284]	[98,330,NaN]	3	hSpCas9	negative selection	9959544
52811816	52811839	12	+	27869803	HPAFII	viability after 35 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.6226738772401569	[277]	[195,239,NaN]	4	hSpCas9	negative selection	9959545
52813978	52814001	12	+	27869803	HPAFII	viability after 35 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.05142675412386011	[367]	[193,191,NaN]	0	hSpCas9	negative selection	9959546
52814131	52814154	12	-	27869803	HPAFII	viability after 35 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.3056122766963503	[377]	[48,273,NaN]	-2	hSpCas9	negative selection	9959547
52807208	52807231	12	-	27869803	HPAFII	viability after 31 days	AGCACTGGAGGCATCAGCGGAGG	KRT4	ENSG00000170477	0.8608251174627287	[376]	[344,426,NaN]	6	hSpCas9	negative selection	10041991
52807777	52807800	12	-	27869803	HPAFII	viability after 31 days	CCACAGCAAGCGCGTAGAGCTGG	KRT4	ENSG00000170477	0.4938431909981718	[242]	[125,263,NaN]	3	hSpCas9	negative selection	10041992
52808808	52808831	12	+	27869803	HPAFII	viability after 31 days	CCACGGACGTGTCGCTGACATGG	KRT4	ENSG00000170477	0.7193124771664521	[284]	[80,461,NaN]	5	hSpCas9	negative selection	10041993
52811816	52811839	12	+	27869803	HPAFII	viability after 31 days	GCGCCCTTTGTCATTGCCCAAGG	KRT4	ENSG00000170477	0.5600545842165082	[277]	[263,192,NaN]	4	hSpCas9	negative selection	10041994
52813978	52814001	12	+	27869803	HPAFII	viability after 31 days	TCTCTTGCCACCGCCTACAATGG	KRT4	ENSG00000170477	0.35377392554507425	[367]	[250,277,NaN]	2	hSpCas9	negative selection	10041995
52814131	52814154	12	-	27869803	HPAFII	viability after 31 days	CCAGGACATATAAGAGACGAAGG	KRT4	ENSG00000170477	-0.6947404219983374	[377]	[98,165,NaN]	-4	hSpCas9	negative selection	10041996
52814003	52814026	12	+	28162770	P31FUJ	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.18988886740790045	[93]	[125]	2	hSpCas9	negative selection	10181535
52814027	52814050	12	-	28162770	P31FUJ	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.21198263825851693	[107]	[146]	2	hSpCas9	negative selection	10181536
52813985	52814008	12	-	28162770	P31FUJ	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.833599021308131	[137]	[288]	8	hSpCas9	negative selection	10181537
52811845	52811868	12	+	28162770	P31FUJ	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.7381353299831587	[350]	[687]	8	hSpCas9	negative selection	10181538
52811779	52811802	12	-	28162770	P31FUJ	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-1.2036558587548623	[97]	[49]	-7	hSpCas9	negative selection	10181539
52813847	52813870	12	-	28162770	P31FUJ	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.5468555309689006	[292]	[502]	6	hSpCas9	negative selection	10181540
52813766	52813789	12	-	28162770	P31FUJ	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.37725127726960794	[322]	[492]	4	hSpCas9	negative selection	10181541
52809373	52809396	12	+	28162770	P31FUJ	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.7269339253718942	[108]	[211]	8	hSpCas9	negative selection	10181542
52808754	52808777	12	-	28162770	P31FUJ	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	0.26362362170512044	[55]	[78]	3	hSpCas9	negative selection	10181543
52807348	52807371	12	+	28162770	P31FUJ	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.25197636615502605	[317]	[444]	2	hSpCas9	negative selection	10181544
52814003	52814026	12	+	28162770	TF1	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	NaN	[NaN]	[43]	1	hSpCas9	negative selection	10350901
52814027	52814050	12	-	28162770	TF1	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	NaN	[NaN]	[62]	1	hSpCas9	negative selection	10350902
52813985	52814008	12	-	28162770	TF1	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	NaN	[NaN]	[290]	1	hSpCas9	negative selection	10350903
52811845	52811868	12	+	28162770	TF1	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	NaN	[NaN]	[346]	1	hSpCas9	negative selection	10350904
52811779	52811802	12	-	28162770	TF1	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	NaN	[NaN]	[171]	1	hSpCas9	negative selection	10350905
52813847	52813870	12	-	28162770	TF1	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	NaN	[NaN]	[261]	1	hSpCas9	negative selection	10350906
52813766	52813789	12	-	28162770	TF1	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	NaN	[NaN]	[305]	1	hSpCas9	negative selection	10350907
52809373	52809396	12	+	28162770	TF1	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	NaN	[NaN]	[108]	1	hSpCas9	negative selection	10350908
52808754	52808777	12	-	28162770	TF1	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10350909
52807348	52807371	12	+	28162770	TF1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	NaN	[NaN]	[255]	1	hSpCas9	negative selection	10350910
52814003	52814026	12	+	28162770	SKM1	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.4378654287331052	[37]	[90]	4	hSpCas9	negative selection	10520267
52814027	52814050	12	-	28162770	SKM1	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.10399772053421752	[19]	[37]	1	hSpCas9	negative selection	10520268
52813985	52814008	12	-	28162770	SKM1	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.6634251291482361	[44]	[125]	6	hSpCas9	negative selection	10520269
52811845	52811868	12	+	28162770	SKM1	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.2426512603202482	[119]	[250]	2	hSpCas9	negative selection	10520270
52811779	52811802	12	-	28162770	SKM1	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	1.2136222117087159	[19]	[81]	9	hSpCas9	negative selection	10520271
52813847	52813870	12	-	28162770	SKM1	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	-0.10740391688425399	[116]	[191]	-1	hSpCas9	negative selection	10520272
52813766	52813789	12	-	28162770	SKM1	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.6487897827798397	[91]	[254]	6	hSpCas9	negative selection	10520273
52809373	52809396	12	+	28162770	SKM1	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.47916783669855956	[27]	[68]	4	hSpCas9	negative selection	10520274
52808754	52808777	12	-	28162770	SKM1	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	-0.5996092766855576	[11]	[13]	-5	hSpCas9	negative selection	10520275
52807348	52807371	12	+	28162770	SKM1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.5267264562090721	[63]	[162]	5	hSpCas9	negative selection	10520276
52814003	52814026	12	+	28162770	SKM1	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.4378654287331052	[37]	[90]	4	hSpCas9	negative selection	10689633
52814027	52814050	12	-	28162770	SKM1	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.10399772053421752	[19]	[37]	1	hSpCas9	negative selection	10689634
52813985	52814008	12	-	28162770	SKM1	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.6634251291482361	[44]	[125]	6	hSpCas9	negative selection	10689635
52811845	52811868	12	+	28162770	SKM1	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.2426512603202482	[119]	[250]	2	hSpCas9	negative selection	10689636
52811779	52811802	12	-	28162770	SKM1	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	1.2136222117087159	[19]	[81]	9	hSpCas9	negative selection	10689637
52813847	52813870	12	-	28162770	SKM1	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	-0.10740391688425399	[116]	[191]	-1	hSpCas9	negative selection	10689638
52813766	52813789	12	-	28162770	SKM1	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.6487897827798397	[91]	[254]	6	hSpCas9	negative selection	10689639
52809373	52809396	12	+	28162770	SKM1	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.47916783669855956	[27]	[68]	4	hSpCas9	negative selection	10689640
52808754	52808777	12	-	28162770	SKM1	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	-0.5996092766855576	[11]	[13]	-5	hSpCas9	negative selection	10689641
52807348	52807371	12	+	28162770	SKM1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.5267264562090721	[63]	[162]	5	hSpCas9	negative selection	10689642
52814003	52814026	12	+	28162770	PL21	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.14399653645178634	[130]	[62]	1	hSpCas9	negative selection	10858999
52814027	52814050	12	-	28162770	PL21	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	1.0718155175137805	[93]	[85]	8	hSpCas9	negative selection	10859000
52813985	52814008	12	-	28162770	PL21	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.6869677968361741	[146]	[102]	6	hSpCas9	negative selection	10859001
52811845	52811868	12	+	28162770	PL21	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.3403172725375805	[391]	[215]	3	hSpCas9	negative selection	10859002
52811779	52811802	12	-	28162770	PL21	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	0.23256109218169752	[87]	[44]	2	hSpCas9	negative selection	10859003
52813847	52813870	12	-	28162770	PL21	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.33284215197543376	[300]	[164]	3	hSpCas9	negative selection	10859004
52813766	52813789	12	-	28162770	PL21	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.7955640540291006	[228]	[172]	6	hSpCas9	negative selection	10859005
52809373	52809396	12	+	28162770	PL21	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	-0.9986402496251772	[100]	[21]	-6	hSpCas9	negative selection	10859006
52808754	52808777	12	-	28162770	PL21	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	1.84059722780218	[33]	[52]	9	hSpCas9	negative selection	10859007
52807348	52807371	12	+	28162770	PL21	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.3262968096253805	[313]	[108]	-2	hSpCas9	negative selection	10859008
52814003	52814026	12	+	28162770	P31FUJ	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.18988886740790045	[93]	[125]	2	hSpCas9	negative selection	11028365
52814027	52814050	12	-	28162770	P31FUJ	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.21198263825851693	[107]	[146]	2	hSpCas9	negative selection	11028366
52813985	52814008	12	-	28162770	P31FUJ	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.833599021308131	[137]	[288]	8	hSpCas9	negative selection	11028367
52811845	52811868	12	+	28162770	P31FUJ	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.7381353299831587	[350]	[687]	8	hSpCas9	negative selection	11028368
52811779	52811802	12	-	28162770	P31FUJ	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-1.2036558587548623	[97]	[49]	-7	hSpCas9	negative selection	11028369
52813847	52813870	12	-	28162770	P31FUJ	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.5468555309689006	[292]	[502]	6	hSpCas9	negative selection	11028370
52813766	52813789	12	-	28162770	P31FUJ	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.37725127726960794	[322]	[492]	4	hSpCas9	negative selection	11028371
52809373	52809396	12	+	28162770	P31FUJ	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.7269339253718942	[108]	[211]	8	hSpCas9	negative selection	11028372
52808754	52808777	12	-	28162770	P31FUJ	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	0.26362362170512044	[55]	[78]	3	hSpCas9	negative selection	11028373
52807348	52807371	12	+	28162770	P31FUJ	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.25197636615502605	[317]	[444]	2	hSpCas9	negative selection	11028374
52814003	52814026	12	+	28162770	OCIAML5	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	1.0630445315494899	[34]	[131]	8	hSpCas9	negative selection	11197731
52814027	52814050	12	-	28162770	OCIAML5	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	-0.5673370939308842	[54]	[66]	-4	hSpCas9	negative selection	11197732
52813985	52814008	12	-	28162770	OCIAML5	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	1.0790715709911987	[58]	[224]	8	hSpCas9	negative selection	11197733
52811845	52811868	12	+	28162770	OCIAML5	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.4221083925749972	[214]	[519]	3	hSpCas9	negative selection	11197734
52811779	52811802	12	-	28162770	OCIAML5	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	0.812749237546374	[40]	[129]	7	hSpCas9	negative selection	11197735
52813847	52813870	12	-	28162770	OCIAML5	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.45525711111459355	[138]	[343]	4	hSpCas9	negative selection	11197736
52813766	52813789	12	-	28162770	OCIAML5	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.8440267418866813	[178]	[579]	7	hSpCas9	negative selection	11197737
52809373	52809396	12	+	28162770	OCIAML5	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.3703258504724509	[38]	[90]	3	hSpCas9	negative selection	11197738
52808754	52808777	12	-	28162770	OCIAML5	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	1.8920945247064132	[9]	[66]	9	hSpCas9	negative selection	11197739
52807348	52807371	12	+	28162770	OCIAML5	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.7829869778733821	[216]	[673]	7	hSpCas9	negative selection	11197740
52814003	52814026	12	+	28162770	EOL1	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.12332763568503191	[175]	[100]	1	hSpCas9	negative selection	11367097
52814027	52814050	12	-	28162770	EOL1	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.11420899107410909	[120]	[68]	1	hSpCas9	negative selection	11367098
52813985	52814008	12	-	28162770	EOL1	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	-0.27137243840472247	[251]	[109]	-2	hSpCas9	negative selection	11367099
52811845	52811868	12	+	28162770	EOL1	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.7964429458228492	[764]	[699]	7	hSpCas9	negative selection	11367100
52811779	52811802	12	-	28162770	EOL1	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	0.1026932798178154	[174]	[98]	0	hSpCas9	negative selection	11367101
52813847	52813870	12	-	28162770	EOL1	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.27780907326268844	[500]	[319]	2	hSpCas9	negative selection	11367102
52813766	52813789	12	-	28162770	EOL1	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.14624138202342893	[294]	[171]	1	hSpCas9	negative selection	11367103
52809373	52809396	12	+	28162770	EOL1	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	-0.2109671990859463	[144]	[65]	-2	hSpCas9	negative selection	11367104
52808754	52808777	12	-	28162770	EOL1	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	-1.2718494412329693	[54]	[11]	-7	hSpCas9	negative selection	11367105
52807348	52807371	12	+	28162770	EOL1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	-0.18488546951541027	[396]	[183]	-1	hSpCas9	negative selection	11367106
52814003	52814026	12	+	28162770	MOLM13	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	1.7707086534842365	[151]	[374]	9	hSpCas9	negative selection	11536463
52814027	52814050	12	-	28162770	MOLM13	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	-0.9553220491799652	[117]	[43]	-5	hSpCas9	negative selection	11536464
52813985	52814008	12	-	28162770	MOLM13	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	1.181585196387938	[174]	[286]	8	hSpCas9	negative selection	11536465
52811845	52811868	12	+	28162770	MOLM13	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.547178291349218	[530]	[560]	4	hSpCas9	negative selection	11536466
52811779	52811802	12	-	28162770	MOLM13	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	1.8699878251159245	[111]	[295]	9	hSpCas9	negative selection	11536467
52813847	52813870	12	-	28162770	MOLM13	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.22837769856420864	[437]	[370]	1	hSpCas9	negative selection	11536468
52813766	52813789	12	-	28162770	MOLM13	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	1.0081732918345094	[316]	[460]	7	hSpCas9	negative selection	11536469
52809373	52809396	12	+	28162770	MOLM13	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	3.016782627558213	[107]	[631]	9	hSpCas9	negative selection	11536470
52808754	52808777	12	-	28162770	MOLM13	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	-1.8540387133427831	[59]	[11]	-7	hSpCas9	negative selection	11536471
52807348	52807371	12	+	28162770	MOLM13	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	1.0500532489130618	[343]	[514]	7	hSpCas9	negative selection	11536472
52814003	52814026	12	+	28162770	HEL	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.1300905360950908	[106]	[74]	1	hSpCas9	negative selection	11705829
52814027	52814050	12	-	28162770	HEL	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.05777633127920079	[89]	[59]	0	hSpCas9	negative selection	11705830
52813985	52814008	12	-	28162770	HEL	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	1.0514348044053743	[170]	[226]	8	hSpCas9	negative selection	11705831
52811845	52811868	12	+	28162770	HEL	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.69149101035873	[610]	[631]	6	hSpCas9	negative selection	11705832
52811779	52811802	12	-	28162770	HEL	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	1.558800013500461	[114]	[216]	9	hSpCas9	negative selection	11705833
52813847	52813870	12	-	28162770	HEL	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.007079089571431774	[361]	[232]	0	hSpCas9	negative selection	11705834
52813766	52813789	12	-	28162770	HEL	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.143327775394414	[310]	[219]	1	hSpCas9	negative selection	11705835
52809373	52809396	12	+	28162770	HEL	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	-0.4775554017173549	[149]	[68]	-3	hSpCas9	negative selection	11705836
52808754	52808777	12	-	28162770	HEL	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	0.42701014094491985	[35]	[30]	3	hSpCas9	negative selection	11705837
52807348	52807371	12	+	28162770	HEL	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.43525041760156136	[320]	[277]	3	hSpCas9	negative selection	11705838
52814003	52814026	12	+	28162770	MV411	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.47538949746112386	[110]	[129]	4	hSpCas9	negative selection	11875195
52814027	52814050	12	-	28162770	MV411	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.4318621219202028	[65]	[74]	4	hSpCas9	negative selection	11875196
52813985	52814008	12	-	28162770	MV411	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.01010885914145658	[177]	[150]	0	hSpCas9	negative selection	11875197
52811845	52811868	12	+	28162770	MV411	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.6100076301674835	[384]	[494]	5	hSpCas9	negative selection	11875198
52811779	52811802	12	-	28162770	MV411	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-0.04432857359433462	[70]	[57]	0	hSpCas9	negative selection	11875199
52813847	52813870	12	-	28162770	MV411	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.20724846066707658	[363]	[353]	1	hSpCas9	negative selection	11875200
52813766	52813789	12	-	28162770	MV411	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.09466727037952985	[208]	[187]	0	hSpCas9	negative selection	11875201
52809373	52809396	12	+	28162770	MV411	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.4982456542833098	[78]	[93]	4	hSpCas9	negative selection	11875202
52808754	52808777	12	-	28162770	MV411	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	1.4698299721192232	[26]	[62]	9	hSpCas9	negative selection	11875203
52807348	52807371	12	+	28162770	MV411	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.3120466322058517	[261]	[273]	2	hSpCas9	negative selection	11875204
52814003	52814026	12	+	28162770	MONOMAC1	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	0.06599755877424013	[94]	[113]	0	hSpCas9	negative selection	12044561
52814027	52814050	12	-	28162770	MONOMAC1	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	-0.029926861224295553	[56]	[63]	0	hSpCas9	negative selection	12044562
52813985	52814008	12	-	28162770	MONOMAC1	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	0.937759930979157	[96]	[212]	8	hSpCas9	negative selection	12044563
52811845	52811868	12	+	28162770	MONOMAC1	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.17186211403999008	[277]	[358]	1	hSpCas9	negative selection	12044564
52811779	52811802	12	-	28162770	MONOMAC1	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	1.0349098809901431	[42]	[100]	8	hSpCas9	negative selection	12044565
52813847	52813870	12	-	28162770	MONOMAC1	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	0.6038918058386175	[224]	[391]	6	hSpCas9	negative selection	12044566
52813766	52813789	12	-	28162770	MONOMAC1	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.8081433920461265	[138]	[278]	7	hSpCas9	negative selection	12044567
52809373	52809396	12	+	28162770	MONOMAC1	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	0.6509600594953966	[44]	[80]	6	hSpCas9	negative selection	12044568
52808754	52808777	12	-	28162770	MONOMAC1	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	2.284089842677063	[11]	[66]	9	hSpCas9	negative selection	12044569
52807348	52807371	12	+	28162770	MONOMAC1	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.32729929471010183	[161]	[232]	3	hSpCas9	negative selection	12044570
52814003	52814026	12	+	28162770	OCIAML2	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	-0.3966292437983844	[18]	[79]	-3	hSpCas9	negative selection	12213927
52814027	52814050	12	-	28162770	OCIAML2	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	-0.5272133536085291	[12]	[49]	-4	hSpCas9	negative selection	12213928
52813985	52814008	12	-	28162770	OCIAML2	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	1.0934539458030788	[28]	[342]	9	hSpCas9	negative selection	12213929
52811845	52811868	12	+	28162770	OCIAML2	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.45161501724339326	[80]	[613]	4	hSpCas9	negative selection	12213930
52811779	52811802	12	-	28162770	OCIAML2	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-0.011198206604863925	[21]	[120]	0	hSpCas9	negative selection	12213931
52813847	52813870	12	-	28162770	OCIAML2	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	2.0933251816491025	[48]	[1158]	9	hSpCas9	negative selection	12213932
52813766	52813789	12	-	28162770	OCIAML2	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	1.2155115098463625	[38]	[501]	9	hSpCas9	negative selection	12213933
52809373	52809396	12	+	28162770	OCIAML2	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	-0.1811232080471763	[17]	[87]	-1	hSpCas9	negative selection	12213934
52808754	52808777	12	-	28162770	OCIAML2	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	1.1814468713375317	[6]	[87]	9	hSpCas9	negative selection	12213935
52807348	52807371	12	+	28162770	OCIAML2	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.18648246123483017	[38]	[245]	1	hSpCas9	negative selection	12213936
52814003	52814026	12	+	28162770	OCIAML3	viability	GAGCCACAGCTGAAGCCCCGGGG	KRT4	ENSG00000170477	-0.4364663633376833	[25]	[57]	-3	hSpCas9	negative selection	12383293
52814027	52814050	12	-	28162770	OCIAML3	viability	AGACAGCAGTGTGTCCGAGGCGG	KRT4	ENSG00000170477	0.20245896559070475	[18]	[65]	2	hSpCas9	negative selection	12383294
52813985	52814008	12	-	28162770	OCIAML3	viability	GGCTCGGCCATTGTAGGCGGTGG	KRT4	ENSG00000170477	1.135726384610967	[29]	[198]	8	hSpCas9	negative selection	12383295
52811845	52811868	12	+	28162770	OCIAML3	viability	GCTGCTTCCTCAGGACACTGAGG	KRT4	ENSG00000170477	0.7019252460302545	[111]	[549]	6	hSpCas9	negative selection	12383296
52811779	52811802	12	-	28162770	OCIAML3	viability	GAAGACCATGCAGGACAGCGTGG	KRT4	ENSG00000170477	-0.6871170447156447	[23]	[44]	-5	hSpCas9	negative selection	12383297
52813847	52813870	12	-	28162770	OCIAML3	viability	AGTGTGGCTGGGTCACGACAAGG	KRT4	ENSG00000170477	-0.05148040592340347	[68]	[200]	0	hSpCas9	negative selection	12383298
52813766	52813789	12	-	28162770	OCIAML3	viability	GGCTCCTTCAGTGGTAAGGGTGG	KRT4	ENSG00000170477	0.29233557788026965	[65]	[243]	2	hSpCas9	negative selection	12383299
52809373	52809396	12	+	28162770	OCIAML3	viability	GAGCCCTCACCGCATCATAGAGG	KRT4	ENSG00000170477	-0.9454800108255408	[36]	[57]	-6	hSpCas9	negative selection	12383300
52808754	52808777	12	-	28162770	OCIAML3	viability	CCTGGACAGCATTATTGCCGAGG	KRT4	ENSG00000170477	-0.6680082217679404	[9]	[18]	-5	hSpCas9	negative selection	12383301
52807348	52807371	12	+	28162770	OCIAML3	viability	AAGGTACTTACAGATGCTCACGG	KRT4	ENSG00000170477	0.04540264441936932	[51]	[161]	0	hSpCas9	negative selection	12383302