Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3852
• Symbol:KRT5
• Description:keratin 5

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52519888	52519911	12	+	26472758	Jiyoye	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.914752713381489	[59]	[23]	-6	hSpCas9	negative selection	86588
52517169	52517192	12	+	26472758	Jiyoye	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	-1.458807270522439	[112]	[30]	-7	hSpCas9	negative selection	86589
52519808	52519831	12	-	26472758	Jiyoye	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.10284134663324912	[162]	[131]	0	hSpCas9	negative selection	86590
52517207	52517230	12	-	26472758	Jiyoye	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.6015534266727248	[103]	[118]	4	hSpCas9	negative selection	86591
52516692	52516715	12	-	26472758	Jiyoye	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-0.08421300390308523	[96]	[68]	0	hSpCas9	negative selection	86592
52520219	52520242	12	+	26472758	Jiyoye	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.48764238180207015	[118]	[63]	-3	hSpCas9	negative selection	86593
52520204	52520227	12	+	26472758	Jiyoye	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-2.480349889235714	[110]	[14]	-9	hSpCas9	negative selection	86594
52520051	52520074	12	+	26472758	Jiyoye	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	1.1046126114854422	[110]	[179]	7	hSpCas9	negative selection	86595
52519920	52519943	12	-	26472758	Jiyoye	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	2.3247132213139006	[17]	[67]	9	hSpCas9	negative selection	86596
52519013	52519036	12	-	26472758	Jiyoye	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	4.407175381505873	[0]	[15]	9	hSpCas9	negative selection	86597
52518989	52519012	12	-	26472758	Jiyoye	viability	GGAACGGGGCCGCCTGGACTCAG	KRT5	ENSG00000186081	0.9921378822270295	[27]	[41]	6	hSpCas9	negative selection	86619
52519888	52519911	12	+	26472758	KBM7	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.3799104083063747	[266,163]	[50,98]	-3	hSpCas9	negative selection	277706
52517169	52517192	12	+	26472758	KBM7	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.4478633621488039	[348,232]	[150,212]	5	hSpCas9	negative selection	277707
52519808	52519831	12	-	26472758	KBM7	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.6774749310366366	[392,252]	[253,224]	7	hSpCas9	negative selection	277708
52517207	52517230	12	-	26472758	KBM7	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.3574713751505807	[399,440]	[268,243]	4	hSpCas9	negative selection	277709
52516692	52516715	12	-	26472758	KBM7	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-0.3130701137165783	[413,275]	[108,145]	-3	hSpCas9	negative selection	277710
52520219	52520242	12	+	26472758	KBM7	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.9947203355368262	[386,308]	[117,48]	-6	hSpCas9	negative selection	277711
52520204	52520227	12	+	26472758	KBM7	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.06042990312017832	[280,459]	[256,95]	0	hSpCas9	negative selection	277712
52520051	52520074	12	+	26472758	KBM7	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.3281091460315577	[653,733]	[365,456]	3	hSpCas9	negative selection	277713
52519920	52519943	12	-	26472758	KBM7	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	-0.048084194998216034	[227,193]	[111,80]	0	hSpCas9	negative selection	277714
52519013	52519036	12	-	26472758	KBM7	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	0.18524405984584558	[59,49]	[42,16]	2	hSpCas9	negative selection	277715
52518989	52519012	12	-	26472758	KBM7	viability	GGAACGGGGCCGCCTGGACTCAG	KRT5	ENSG00000186081	0.7687408847353805	[307,189]	[202,188]	8	hSpCas9	negative selection	277737
52519888	52519911	12	+	26472758	Raji	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.6999713866840045	[118]	[16]	-5	hSpCas9	negative selection	468824
52517169	52517192	12	+	26472758	Raji	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.4966579385873615	[112]	[36]	5	hSpCas9	negative selection	468825
52519808	52519831	12	-	26472758	Raji	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.39843231737698986	[169]	[51]	4	hSpCas9	negative selection	468826
52517207	52517230	12	-	26472758	Raji	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.3815584988125936	[171]	[51]	3	hSpCas9	negative selection	468827
52516692	52516715	12	-	26472758	Raji	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	0.09178668032258097	[185]	[45]	0	hSpCas9	negative selection	468828
52520219	52520242	12	+	26472758	Raji	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.6398503942464335	[140]	[20]	-5	hSpCas9	negative selection	468829
52520204	52520227	12	+	26472758	Raji	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-2.501425707301925	[243]	[9]	-9	hSpCas9	negative selection	468830
52520051	52520074	12	+	26472758	Raji	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.6356316451004344	[293]	[105]	6	hSpCas9	negative selection	468831
52519920	52519943	12	-	26472758	Raji	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.21864028647534034	[236]	[63]	2	hSpCas9	negative selection	468832
52519013	52519036	12	-	26472758	Raji	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	2.7594602319532924	[6]	[10]	9	hSpCas9	negative selection	468833
52518989	52519012	12	-	26472758	Raji	viability	GGAACGGGGCCGCCTGGACTCAG	KRT5	ENSG00000186081	1.4149563372838918	[201]	[124]	9	hSpCas9	negative selection	468855
52519888	52519911	12	+	26472758	K562	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-1.5153181741584176	[148]	[43]	-6	hSpCas9	negative selection	659942
52517169	52517192	12	+	26472758	K562	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	1.4454374982103282	[203]	[468]	9	hSpCas9	negative selection	659943
52519808	52519831	12	-	26472758	K562	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	-1.5695692867236044	[326]	[92]	-7	hSpCas9	negative selection	659944
52517207	52517230	12	-	26472758	K562	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.26572923391185904	[335]	[340]	2	hSpCas9	negative selection	659945
52516692	52516715	12	-	26472758	K562	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-1.1421623255631688	[250]	[95]	-6	hSpCas9	negative selection	659946
52520219	52520242	12	+	26472758	K562	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-1.2005810096282643	[372]	[136]	-6	hSpCas9	negative selection	659947
52520204	52520227	12	+	26472758	K562	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.473081043911295	[318]	[96]	-6	hSpCas9	negative selection	659948
52520051	52520074	12	+	26472758	K562	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.6190124012341761	[623]	[808]	5	hSpCas9	negative selection	659949
52519920	52519943	12	-	26472758	K562	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	1.3773701334696706	[201]	[442]	9	hSpCas9	negative selection	659950
52519013	52519036	12	-	26472758	K562	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	1.5663468225538089	[19]	[49]	9	hSpCas9	negative selection	659951
52518989	52519012	12	-	26472758	K562	viability	GGAACGGGGCCGCCTGGACTCAG	KRT5	ENSG00000186081	-0.017322361145826415	[222]	[185]	0	hSpCas9	negative selection	659973
52514945	52514968	12	+	26627737	DLD1	viability	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.17086082184983642	[85]	[28,21,20]	-2	hSpCas9	negative selection	784241
52515036	52515059	12	-	26627737	DLD1	viability	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.8111328633859192	[1245]	[674,717,661]	7	hSpCas9	negative selection	784242
52520204	52520227	12	+	26627737	DLD1	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.07842599018896479	[94]	[9,39,33]	-1	hSpCas9	negative selection	784243
52520260	52520283	12	-	26627737	DLD1	viability	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.5269935610005453	[802]	[374,414,305]	5	hSpCas9	negative selection	784244
52520262	52520285	12	-	26627737	DLD1	viability	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.293139615058978	[1104]	[362,366,521]	3	hSpCas9	negative selection	784245
52520276	52520299	12	+	26627737	DLD1	viability	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.376679634490243	[1096]	[599,396,350]	4	hSpCas9	negative selection	784246
52514945	52514968	12	+	26627737	GBM cells	viability after 5 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-1.2961021075194574	[86]	[16,20]	-9	hSpCas9	negative selection	866556
52515036	52515059	12	-	26627737	GBM cells	viability after 5 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.6076117440290866	[401]	[374,281]	8	hSpCas9	negative selection	866557
52520204	52520227	12	+	26627737	GBM cells	viability after 5 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.10108612511431492	[3]	[1,1]	-2	hSpCas9	negative selection	866558
52520260	52520283	12	-	26627737	GBM cells	viability after 5 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.6384306545812238	[338]	[278,286]	8	hSpCas9	negative selection	866559
52520262	52520285	12	-	26627737	GBM cells	viability after 5 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.49195460768299326	[652]	[505,478]	7	hSpCas9	negative selection	866560
52520276	52520299	12	+	26627737	GBM cells	viability after 5 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.8504330736472743	[347]	[366,305]	9	hSpCas9	negative selection	866561
52514945	52514968	12	+	26627737	GBM cells	viability after 13 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.44159406416197067	[86]	[31,36]	-5	hSpCas9	negative selection	948871
52515036	52515059	12	-	26627737	GBM cells	viability after 13 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.9003273238406094	[401]	[421,394]	9	hSpCas9	negative selection	948872
52520204	52520227	12	+	26627737	GBM cells	viability after 13 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.19413246224863823	[3]	[2,0]	-2	hSpCas9	negative selection	948873
52520260	52520283	12	-	26627737	GBM cells	viability after 13 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.4239539145189498	[338]	[259,235]	5	hSpCas9	negative selection	948874
52520262	52520285	12	-	26627737	GBM cells	viability after 13 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.5784883704900097	[652]	[538,520]	7	hSpCas9	negative selection	948875
52520276	52520299	12	+	26627737	GBM cells	viability after 13 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.5052488181874915	[347]	[342,206]	6	hSpCas9	negative selection	948876
52514945	52514968	12	+	26627737	GBM cells	viability after 21 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.6188930316261942	[86]	[35,25]	-5	hSpCas9	negative selection	1031186
52515036	52515059	12	-	26627737	GBM cells	viability after 21 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.8400834085965684	[401]	[379,400]	8	hSpCas9	negative selection	1031187
52520204	52520227	12	+	26627737	GBM cells	viability after 21 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.1197667003843419	[3]	[1,1]	-1	hSpCas9	negative selection	1031188
52520260	52520283	12	-	26627737	GBM cells	viability after 21 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	1.065096617862101	[338]	[388,381]	9	hSpCas9	negative selection	1031189
52520262	52520285	12	-	26627737	GBM cells	viability after 21 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.5590414614632797	[652]	[553,493]	6	hSpCas9	negative selection	1031190
52520276	52520299	12	+	26627737	GBM cells	viability after 21 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.4529836108720752	[347]	[286,232]	4	hSpCas9	negative selection	1031191
52514945	52514968	12	+	26627737	RPE1	viability after 9 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.22112723507387466	[418]	[129,89]	-1	hSpCas9	negative selection	1113501
52515036	52515059	12	-	26627737	RPE1	viability after 9 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	1.3449860338204414	[1788]	[1520,1295]	7	hSpCas9	negative selection	1113502
52520204	52520227	12	+	26627737	RPE1	viability after 9 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-5.56295820901026	[150]	[0,0]	-9	hSpCas9	negative selection	1113503
52520260	52520283	12	-	26627737	RPE1	viability after 9 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	1.8048911377705739	[581]	[454,870]	8	hSpCas9	negative selection	1113504
52520262	52520285	12	-	26627737	RPE1	viability after 9 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.36543407889271284	[1755]	[602,843]	2	hSpCas9	negative selection	1113505
52520276	52520299	12	+	26627737	RPE1	viability after 9 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.8185650140553251	[2147]	[341,431]	-5	hSpCas9	negative selection	1113506
52514945	52514968	12	+	26627737	RPE1	viability after 12 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.7597225435658317	[418]	[31,102]	-5	hSpCas9	negative selection	1195816
52515036	52515059	12	-	26627737	RPE1	viability after 12 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	1.422826498925425	[1788]	[1548,1012]	7	hSpCas9	negative selection	1195817
52520204	52520227	12	+	26627737	RPE1	viability after 12 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.0183057105862847	[150]	[37,0]	-6	hSpCas9	negative selection	1195818
52520260	52520283	12	-	26627737	RPE1	viability after 12 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	1.8860904348691223	[581]	[627,524]	8	hSpCas9	negative selection	1195819
52520262	52520285	12	-	26627737	RPE1	viability after 12 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.500997908021992	[1755]	[587,751]	3	hSpCas9	negative selection	1195820
52520276	52520299	12	+	26627737	RPE1	viability after 12 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-1.0051770355514082	[2147]	[287,286]	-6	hSpCas9	negative selection	1195821
52514945	52514968	12	+	26627737	RPE1	viability after 15 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-1.8009228717575234	[418]	[4,61]	-8	hSpCas9	negative selection	1278131
52515036	52515059	12	-	26627737	RPE1	viability after 15 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	1.618119829012669	[1788]	[2368,766]	8	hSpCas9	negative selection	1278132
52520204	52520227	12	+	26627737	RPE1	viability after 15 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.1197500370402547	[150]	[38,0]	-6	hSpCas9	negative selection	1278133
52520260	52520283	12	-	26627737	RPE1	viability after 15 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	2.0715300590389103	[581]	[634,746]	8	hSpCas9	negative selection	1278134
52520262	52520285	12	-	26627737	RPE1	viability after 15 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.5034603205525319	[1755]	[834,577]	3	hSpCas9	negative selection	1278135
52520276	52520299	12	+	26627737	RPE1	viability after 15 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.6494402580325968	[2147]	[309,461]	-4	hSpCas9	negative selection	1278136
52514945	52514968	12	+	26627737	RPE1	viability after 18 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-1.1820761326866527	[418]	[44,54]	-6	hSpCas9	negative selection	1360446
52515036	52515059	12	-	26627737	RPE1	viability after 18 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	1.4703936780078644	[1788]	[1754,891]	7	hSpCas9	negative selection	1360447
52520204	52520227	12	+	26627737	RPE1	viability after 18 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.094704211010182	[150]	[35,0]	-6	hSpCas9	negative selection	1360448
52520260	52520283	12	-	26627737	RPE1	viability after 18 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	2.080069167349686	[581]	[710,613]	8	hSpCas9	negative selection	1360449
52520262	52520285	12	-	26627737	RPE1	viability after 18 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.11909009548456351	[1755]	[504,524]	0	hSpCas9	negative selection	1360450
52520276	52520299	12	+	26627737	RPE1	viability after 18 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.9876005048333683	[2147]	[141,452]	-6	hSpCas9	negative selection	1360451
52514945	52514968	12	+	26627737	HeLa	viability after 8 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.9076333471344094	[187]	[99,10,32]	-7	hSpCas9	negative selection	1442761
52515036	52515059	12	-	26627737	HeLa	viability after 8 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.6569698504541107	[694]	[504,458,472]	5	hSpCas9	negative selection	1442762
52520204	52520227	12	+	26627737	HeLa	viability after 8 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	0.14674651792705173	[71]	[78,2,31]	1	hSpCas9	negative selection	1442763
52520260	52520283	12	-	26627737	HeLa	viability after 8 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.6594575681655079	[486]	[493,266,281]	5	hSpCas9	negative selection	1442764
52520262	52520285	12	-	26627737	HeLa	viability after 8 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.3158147917685914	[844]	[554,419,421]	3	hSpCas9	negative selection	1442765
52520276	52520299	12	+	26627737	HeLa	viability after 8 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.6244023443237261	[1281]	[343,528,218]	-6	hSpCas9	negative selection	1442766
52514945	52514968	12	+	26627737	HeLa	viability after 12 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-3.5378431738740934	[187]	[17,0,1]	-9	hSpCas9	negative selection	1525076
52515036	52515059	12	-	26627737	HeLa	viability after 12 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.6718505015783146	[694]	[277,584,490]	5	hSpCas9	negative selection	1525077
52520204	52520227	12	+	26627737	HeLa	viability after 12 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.33764643178019904	[71]	[56,0,15]	-3	hSpCas9	negative selection	1525078
52520260	52520283	12	-	26627737	HeLa	viability after 12 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.6481998234076038	[486]	[319,252,379]	5	hSpCas9	negative selection	1525079
52520262	52520285	12	-	26627737	HeLa	viability after 12 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.17155570463871994	[844]	[426,363,392]	1	hSpCas9	negative selection	1525080
52520276	52520299	12	+	26627737	HeLa	viability after 12 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-1.3459456055559018	[1281]	[125,244,247]	-8	hSpCas9	negative selection	1525081
52514945	52514968	12	+	26627737	HeLa	viability after 15 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-2.9061424955194313	[187]	[3,12,13]	-9	hSpCas9	negative selection	1607391
52515036	52515059	12	-	26627737	HeLa	viability after 15 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	1.1026306500332965	[694]	[617,616,585]	7	hSpCas9	negative selection	1607392
52520204	52520227	12	+	26627737	HeLa	viability after 15 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.011644923304077182	[71]	[22,50,11]	0	hSpCas9	negative selection	1607393
52520260	52520283	12	-	26627737	HeLa	viability after 15 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.5392830908311568	[486]	[179,285,408]	4	hSpCas9	negative selection	1607394
52520262	52520285	12	-	26627737	HeLa	viability after 15 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.0751850489186443	[844]	[233,345,520]	0	hSpCas9	negative selection	1607395
52520276	52520299	12	+	26627737	HeLa	viability after 15 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-1.2353420673861746	[1281]	[190,281,189]	-8	hSpCas9	negative selection	1607396
52514945	52514968	12	+	26627737	HeLa	viability after 18 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-2.9425815667995856	[187]	[1,10,13]	-9	hSpCas9	negative selection	1689706
52515036	52515059	12	-	26627737	HeLa	viability after 18 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	1.0810202677054335	[694]	[396,510,585]	7	hSpCas9	negative selection	1689707
52520204	52520227	12	+	26627737	HeLa	viability after 18 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	0.08656940474791375	[71]	[17,43,11]	0	hSpCas9	negative selection	1689708
52520260	52520283	12	-	26627737	HeLa	viability after 18 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.5611863098295622	[486]	[125,240,408]	4	hSpCas9	negative selection	1689709
52520262	52520285	12	-	26627737	HeLa	viability after 18 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.062019121167276925	[844]	[150,285,520]	0	hSpCas9	negative selection	1689710
52520276	52520299	12	+	26627737	HeLa	viability after 18 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-1.2139456639255886	[1281]	[130,237,189]	-8	hSpCas9	negative selection	1689711
52514945	52514968	12	+	26627737	HCT116	viability after 6 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-1.455621146368069	[265]	[2,21]	-7	hSpCas9	negative selection	1772021
52515036	52515059	12	-	26627737	HCT116	viability after 6 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.25127195592008733	[1826]	[502,252]	1	hSpCas9	negative selection	1772022
52520204	52520227	12	+	26627737	HCT116	viability after 6 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.49045376508828686	[382]	[96,12]	-3	hSpCas9	negative selection	1772023
52520260	52520283	12	-	26627737	HCT116	viability after 6 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.17731827169525216	[1249]	[441,100]	1	hSpCas9	negative selection	1772024
52520262	52520285	12	-	26627737	HCT116	viability after 6 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	-1.019314447478044	[2022]	[221,120]	-5	hSpCas9	negative selection	1772025
52520276	52520299	12	+	26627737	HCT116	viability after 6 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.07467797355459926	[1539]	[245,220]	0	hSpCas9	negative selection	1772026
52514945	52514968	12	+	26627737	HCT116	viability after 8 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.1938419363263859	[110]	[45,36,76]	-2	hSpCas9	negative selection	1854336
52515036	52515059	12	-	26627737	HCT116	viability after 8 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.20585103809485084	[692]	[404,421,492]	2	hSpCas9	negative selection	1854337
52520204	52520227	12	+	26627737	HCT116	viability after 8 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.7962040487668813	[128]	[47,39,34]	-7	hSpCas9	negative selection	1854338
52520260	52520283	12	-	26627737	HCT116	viability after 8 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.41195533845595367	[471]	[346,333,356]	4	hSpCas9	negative selection	1854339
52520262	52520285	12	-	26627737	HCT116	viability after 8 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.20963198010614081	[669]	[391,530,357]	2	hSpCas9	negative selection	1854340
52520276	52520299	12	+	26627737	HCT116	viability after 8 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.5549995898722304	[599]	[320,227,128]	-6	hSpCas9	negative selection	1854341
52514945	52514968	12	+	26627737	HCT116	viability after 9 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.7669775234645555	[265]	[48,35]	-5	hSpCas9	negative selection	1936651
52515036	52515059	12	-	26627737	HCT116	viability after 9 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.20179435034227344	[1826]	[545,572]	1	hSpCas9	negative selection	1936652
52520204	52520227	12	+	26627737	HCT116	viability after 9 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.373582137598644	[382]	[34,42]	-7	hSpCas9	negative selection	1936653
52520260	52520283	12	-	26627737	HCT116	viability after 9 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.0820531222809473	[1249]	[626,136]	0	hSpCas9	negative selection	1936654
52520262	52520285	12	-	26627737	HCT116	viability after 9 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	-0.500474531185298	[2022]	[163,553]	-4	hSpCas9	negative selection	1936655
52520276	52520299	12	+	26627737	HCT116	viability after 9 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.34696698598140563	[1539]	[224,400]	-2	hSpCas9	negative selection	1936656
52514945	52514968	12	+	26627737	HCT116	viability after 12 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	0.7161386362701769	[110]	[17,164,112]	6	hSpCas9	negative selection	2018966
52515036	52515059	12	-	26627737	HCT116	viability after 12 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.5721128649539287	[692]	[580,423,612]	5	hSpCas9	negative selection	2018967
52520204	52520227	12	+	26627737	HCT116	viability after 12 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.5982261989514128	[128]	[25,44,64]	-6	hSpCas9	negative selection	2018968
52520260	52520283	12	-	26627737	HCT116	viability after 12 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.8790019205493452	[471]	[342,517,518]	7	hSpCas9	negative selection	2018969
52520262	52520285	12	-	26627737	HCT116	viability after 12 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.34449206134480015	[669]	[461,492,385]	3	hSpCas9	negative selection	2018970
52520276	52520299	12	+	26627737	HCT116	viability after 12 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.372914014290719	[599]	[428,401,391]	3	hSpCas9	negative selection	2018971
52514945	52514968	12	+	26627737	HCT116	viability after 15 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	0.5619318373568359	[110]	[96,35,148]	5	hSpCas9	negative selection	2101281
52515036	52515059	12	-	26627737	HCT116	viability after 15 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.1841170185066503	[692]	[644,369,365]	1	hSpCas9	negative selection	2101282
52520204	52520227	12	+	26627737	HCT116	viability after 15 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	0.32091707135819614	[128]	[45,136,88]	3	hSpCas9	negative selection	2101283
52520260	52520283	12	-	26627737	HCT116	viability after 15 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.6715645155161057	[471]	[386,485,416]	6	hSpCas9	negative selection	2101284
52520262	52520285	12	-	26627737	HCT116	viability after 15 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.23258162743352795	[669]	[405,520,423]	2	hSpCas9	negative selection	2101285
52520276	52520299	12	+	26627737	HCT116	viability after 15 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.29518050419678477	[599]	[342,223,282]	-3	hSpCas9	negative selection	2101286
52514945	52514968	12	+	26627737	HCT116	viability after 18 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.7536175730635406	[110]	[11,26,57]	-6	hSpCas9	negative selection	2183596
52515036	52515059	12	-	26627737	HCT116	viability after 18 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.12870466188333096	[692]	[483,179,450]	1	hSpCas9	negative selection	2183597
52520204	52520227	12	+	26627737	HCT116	viability after 18 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.7148949158054456	[128]	[13,20,21]	-8	hSpCas9	negative selection	2183598
52520260	52520283	12	-	26627737	HCT116	viability after 18 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.9809498052883746	[471]	[418,421,514]	7	hSpCas9	negative selection	2183599
52520262	52520285	12	-	26627737	HCT116	viability after 18 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.3475286935138824	[669]	[390,295,563]	3	hSpCas9	negative selection	2183600
52520276	52520299	12	+	26627737	HCT116	viability after 18 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.19253181440288913	[599]	[339,348,302]	1	hSpCas9	negative selection	2183601
52520634	52520657	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGTATGTCTTCACCATAGAGG	KRT5	ENSG00000186081	0.2837377414809521	[33,21]	[7,6]	1	dCas9-VP64	positive selection	2383992
52520584	52520607	12	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGATCAGTGCTGCAAGGCAAGG	KRT5	ENSG00000186081	0.8197716675488955	[9,11]	[4,1]	3	dCas9-VP64	positive selection	2383993
52520537	52520560	12	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGGTGCAAACGCTTTCTTCCTGG	KRT5	ENSG00000186081	-1.5297157227370095	[112,142]	[7,10]	-8	dCas9-VP64	positive selection	2383994
52520634	52520657	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGTATGTCTTCACCATAGAGG	KRT5	ENSG00000186081	0.2359520604741594	[110,62]	[33,32]	2	dCas9-VP64	positive selection	2479247
52520584	52520607	12	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGATCAGTGCTGCAAGGCAAGG	KRT5	ENSG00000186081	-0.3896357391652295	[96,90]	[33,12]	-4	dCas9-VP64	positive selection	2479248
52520537	52520560	12	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGGTGCAAACGCTTTCTTCCTGG	KRT5	ENSG00000186081	4.566627074859662	[58,100]	[1106,160]	9	dCas9-VP64	positive selection	2479249
52519807	52519830	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCGACCCCAGCATCCAGAGGG	KRT5	ENSG00000186081	0.32661181172811027	[3,4]	[4,4]	7	hSpCas9	positive selection	2998227
52520055	52520078	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATATCCATCAGCACTAGTGGTGG	KRT5	ENSG00000186081	0.860122010343661	[2,2]	[3,6]	9	hSpCas9	positive selection	2998228
52519871	52519894	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCTTGGATACCTCCAGGAGGG	KRT5	ENSG00000186081	0.35384624656191405	[3,2]	[3,3]	7	hSpCas9	positive selection	2998229
52518981	52519004	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTCTCAGCTCTGAGTCCAGGCGG	KRT5	ENSG00000186081	-0.09687703221863167	[3,3]	[2,2]	-1	hSpCas9	positive selection	2998230
52519807	52519830	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCGACCCCAGCATCCAGAGGG	KRT5	ENSG00000186081	-0.22459661976717132	[3,3]	[2,1]	-3	hSpCas9	positive selection	3066085
52520055	52520078	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATATCCATCAGCACTAGTGGTGG	KRT5	ENSG00000186081	-0.2995903671628378	[2,2]	[2,0]	-4	hSpCas9	positive selection	3066086
52519871	52519894	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCTTGGATACCTCCAGGAGGG	KRT5	ENSG00000186081	-0.6361349122733135	[3,3]	[1,0]	-8	hSpCas9	positive selection	3066087
52518981	52519004	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTCTCAGCTCTGAGTCCAGGCGG	KRT5	ENSG00000186081	-0.2857235939208257	[3,3]	[1,1]	-4	hSpCas9	positive selection	3066088
52518115	52518138		+	24336571	A375	resistance to PLX after 7 days	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.22109442204793667	[9,9]	[7,8]	-6	hSpCas9	positive selection	3123800
52518102	52518125		-	24336571	A375	resistance to PLX after 7 days	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.6644173554008266	[6,7]	[10,12]	9	hSpCas9	positive selection	3123801
52518947	52518970		+	24336571	A375	resistance to PLX after 7 days	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.17378273568922253	[7,9]	[7,6]	-5	hSpCas9	positive selection	3123802
52518977	52519000		+	24336571	A375	resistance to PLX after 7 days	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.3954422322685396	[2,1]	[1,1]	-9	hSpCas9	positive selection	3123803
52518115	52518138		+	24336571	A375	resistance to PLX after 14 days	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.22043484432314725	[7,10]	[3,2]	-2	hSpCas9	positive selection	3181593
52518102	52518125		-	24336571	A375	resistance to PLX after 14 days	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	3.591431852330761	[11,9]	[95,31]	9	hSpCas9	positive selection	3181594
52518947	52518970		+	24336571	A375	resistance to PLX after 14 days	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.757812790066613	[10,8]	[2,1]	-8	hSpCas9	positive selection	3181595
52518977	52519000		+	24336571	A375	resistance to PLX after 14 days	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.8174427012687191	[1,1]	[1,1]	7	hSpCas9	positive selection	3181596
52518115	52518138		+	24336571	A375	viability after 7 days	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.6334290442360478	[16]	[9,9]	-7	hSpCas9	negative selection	3239386
52518102	52518125		-	24336571	A375	viability after 7 days	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.019168739941971324	[7]	[6,7]	0	hSpCas9	negative selection	3239387
52518947	52518970		+	24336571	A375	viability after 7 days	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.548655279085698	[13]	[7,9]	-7	hSpCas9	negative selection	3239388
52518977	52519000		+	24336571	A375	viability after 7 days	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.19631892863778733	[1]	[2,1]	3	hSpCas9	negative selection	3239389
52518115	52518138		+	24336571	A375	viability after 14 days	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.7430224989603512	[16]	[7,10]	-7	hSpCas9	negative selection	3297179
52518102	52518125		-	24336571	A375	viability after 14 days	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.5217512933350699	[7]	[11,9]	6	hSpCas9	negative selection	3297180
52518947	52518970		+	24336571	A375	viability after 14 days	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.3439894250876223	[13]	[10,8]	-4	hSpCas9	negative selection	3297181
52518977	52519000		+	24336571	A375	viability after 14 days	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.04534661955981667	[1]	[1,1]	0	hSpCas9	negative selection	3297182
52518947	52518970	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	2.257326211445835	[31,31]	[0,0]	8	hSpCas9	positive selection	3376327
52518115	52518138	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	4.257326211445835	[7,7]	[0,0]	9	hSpCas9	positive selection	3376328
52518102	52518125	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.3504356158373165	[119,119]	[0,0]	1	hSpCas9	positive selection	3376329
52519807	52519830	12	-	26780180	HT29	viability (Avana library 4 designs)	AATCGACCCCAGCATCCAGAGGG	KRT5	ENSG00000186081	0.912828035822472	[]	[]	3	hSpCas9	negative selection	3435681
52520055	52520078	12	-	26780180	HT29	viability (Avana library 4 designs)	ATATCCATCAGCACTAGTGGTGG	KRT5	ENSG00000186081	2.22937717551131	[]	[]	7	hSpCas9	negative selection	3435682
52519870	52519893	12	+	26780180	HT29	viability (Avana library 4 designs)	CCTCTTGGATACCTCCAGGAGGG	KRT5	ENSG00000186081	0.491300089008284	[]	[]	1	hSpCas9	negative selection	3435683
52518980	52519003	12	+	26780180	HT29	viability (Avana library 4 designs)	TTCTCAGCTCTGAGTCCAGGCGG	KRT5	ENSG00000186081	0.89883761748637	[]	[]	3	hSpCas9	negative selection	3435684
52519807	52519830	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATCGACCCCAGCATCCAGAGGG	KRT5	ENSG00000186081	-7.71461611159345	[]	[]	-7	hSpCas9	negative selection	3523367
52520055	52520078	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATATCCATCAGCACTAGTGGTGG	KRT5	ENSG00000186081	-2.3650065594597	[]	[]	-3	hSpCas9	negative selection	3523368
52518980	52519003	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTCTCAGCTCTGAGTCCAGGCGG	KRT5	ENSG00000186081	2.41564572230022	[]	[]	3	hSpCas9	negative selection	3523369
52519870	52519893	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCTTGGATACCTCCAGGAGGG	KRT5	ENSG00000186081	3.77389179186193	[]	[]	6	hSpCas9	negative selection	3523370
52520259	52520282	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGTGTGTCCTTCCGGAGCGGGGG	KRT5	ENSG00000186081	1.54050381418913	[]	[]	2	hSpCas9	negative selection	3523371
52519010	52519033	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCTGGACAGCATCGTGGGGG	KRT5	ENSG00000186081	-6.55395127958568	[]	[]	-6	hSpCas9	negative selection	3523372
52519807	52519830	12	-	26780180	A375	viability (Avana lentiGuide)	AATCGACCCCAGCATCCAGAGGG	KRT5	ENSG00000186081	-3.89407428325335	[]	[]	-6	hSpCas9	negative selection	3632026
52520055	52520078	12	-	26780180	A375	viability (Avana lentiGuide)	ATATCCATCAGCACTAGTGGTGG	KRT5	ENSG00000186081	-4.28027491575204	[]	[]	-7	hSpCas9	negative selection	3632027
52518980	52519003	12	+	26780180	A375	viability (Avana lentiGuide)	TTCTCAGCTCTGAGTCCAGGCGG	KRT5	ENSG00000186081	3.11939339299783	[]	[]	3	hSpCas9	negative selection	3632028
52519870	52519893	12	+	26780180	A375	viability (Avana lentiGuide)	CCTCTTGGATACCTCCAGGAGGG	KRT5	ENSG00000186081	-4.08535362680642	[]	[]	-7	hSpCas9	negative selection	3632029
52520259	52520282	12	-	26780180	A375	viability (Avana lentiGuide)	AGTGTGTCCTTCCGGAGCGGGGG	KRT5	ENSG00000186081	9.08263392249157	[]	[]	6	hSpCas9	negative selection	3632030
52519010	52519033	12	-	26780180	A375	viability (Avana lentiGuide)	GCAGCTGGACAGCATCGTGGGGG	KRT5	ENSG00000186081	6.77043282422498	[]	[]	5	hSpCas9	negative selection	3632031
52519807	52519830	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCGACCCCAGCATCCAGAGGG	KRT5	ENSG00000186081	-0.6501224435786578	[4]	[2,2]	-7	hSpCas9	positive selection	3740685
52520055	52520078	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATATCCATCAGCACTAGTGGTGG	KRT5	ENSG00000186081	-0.408594024497639	[5]	[4,2]	-6	hSpCas9	positive selection	3740686
52518980	52519003	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTCTCAGCTCTGAGTCCAGGCGG	KRT5	ENSG00000186081	-0.028282401719919276	[5]	[6,3]	0	hSpCas9	positive selection	3740687
52519870	52519893	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCTTGGATACCTCCAGGAGGG	KRT5	ENSG00000186081	0.1942568290744376	[5]	[5,6]	5	hSpCas9	positive selection	3740688
52520259	52520282	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGTGTGTCCTTCCGGAGCGGGGG	KRT5	ENSG00000186081	0.16631278788545936	[4]	[5,5]	4	hSpCas9	positive selection	3740689
52519010	52519033	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCTGGACAGCATCGTGGGGG	KRT5	ENSG00000186081	-0.498931687659598	[4]	[3,2]	-6	hSpCas9	positive selection	3740690
52519807	52519830	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCGACCCCAGCATCCAGAGGG	KRT5	ENSG00000186081	-0.016615440049454092	[5]	[2,6]	0	hSpCas9	positive selection	3849292
52520055	52520078	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATATCCATCAGCACTAGTGGTGG	KRT5	ENSG00000186081	-0.27814764177084694	[4]	[4,2]	-4	hSpCas9	positive selection	3849293
52518980	52519003	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTCTCAGCTCTGAGTCCAGGCGG	KRT5	ENSG00000186081	0.05771803601405937	[5]	[5,3]	1	hSpCas9	positive selection	3849294
52519870	52519893	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCTTGGATACCTCCAGGAGGG	KRT5	ENSG00000186081	0.4184684989402336	[4]	[5,4]	9	hSpCas9	positive selection	3849295
52520259	52520282	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGTGTGTCCTTCCGGAGCGGGGG	KRT5	ENSG00000186081	-0.16406663576557765	[5]	[2,5]	-2	hSpCas9	positive selection	3849296
52519010	52519033	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCTGGACAGCATCGTGGGGG	KRT5	ENSG00000186081	-0.022555943520361322	[5]	[5,3]	0	hSpCas9	positive selection	3849297
52517930	52517953	12	+	26780180	A375	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.849634069899428	[]	[]	3	hSpCas9	negative selection	3955376
52518115	52518138	12	+	26780180	A375	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.0480972752808639	[]	[]	0	hSpCas9	negative selection	3955377
52517932	52517955	12	-	26780180	A375	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	1.02014206967116	[]	[]	5	hSpCas9	negative selection	3955378
52518102	52518125	12	-	26780180	A375	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.238293762142537	[]	[]	0	hSpCas9	negative selection	3955379
52518947	52518970	12	+	26780180	A375	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.92777471968544	[]	[]	4	hSpCas9	negative selection	3955380
52518977	52519000	12	+	26780180	A375	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	1.7940510868461	[]	[]	9	hSpCas9	negative selection	3955381
52517930	52517953	12	+	26780180	HT29	viability (GeCKOv2 library)	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.0597953229200928	[]	[]	0	hSpCas9	negative selection	4063342
52518115	52518138	12	+	26780180	HT29	viability (GeCKOv2 library)	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.475158657180166	[]	[]	1	hSpCas9	negative selection	4063343
52517932	52517955	12	-	26780180	HT29	viability (GeCKOv2 library)	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.763473575508176	[]	[]	3	hSpCas9	negative selection	4063344
52518102	52518125	12	-	26780180	HT29	viability (GeCKOv2 library)	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	1.10409968933558	[]	[]	5	hSpCas9	negative selection	4063345
52518947	52518970	12	+	26780180	HT29	viability (GeCKOv2 library)	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	1.28230826787477	[]	[]	6	hSpCas9	negative selection	4063346
52518977	52519000	12	+	26780180	HT29	viability (GeCKOv2 library)	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.639300251053985	[]	[]	2	hSpCas9	negative selection	4063347
52518115	52518138	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.051593137201689815	[3]	[1,1]	-1	hSpCas9	positive selection	4147770
52518102	52518125	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.9049262853297482	[2]	[1,5]	9	hSpCas9	positive selection	4147771
52518947	52518970	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.014505604883560397	[3]	[2,0]	0	hSpCas9	positive selection	4147772
52518977	52519000	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.28462881908382465	[3]	[3,0]	-6	hSpCas9	positive selection	4147773
52518115	52518138	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.301331870078314	[3]	[4,2,1,3]	9	hSpCas9	positive selection	4211792
52518102	52518125	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.9556052347203394	[1]	[3,1,1,0]	6	hSpCas9	positive selection	4211793
52518947	52518970	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.19421851489711772	[3]	[3,0,2,0]	1	hSpCas9	positive selection	4211794
52518977	52519000	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.6345935028390675	[3]	[3,3,2,0]	4	hSpCas9	positive selection	4211795
52517930	52517953	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.27048561188758624	[4]	[4,4]	5	hSpCas9	positive selection	4279185
52517932	52517955	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.12035405717321054	[2]	[2,1]	-2	hSpCas9	positive selection	4279186
52518977	52519000	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.3829420942123565	[3]	[2,1]	-7	hSpCas9	positive selection	4279187
52518947	52518970	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.4560116935686265	[1]	[0,0]	-7	hSpCas9	positive selection	4343440
52518115	52518138	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.1781423819786938	[0]	[0,0]	3	hSpCas9	positive selection	4343441
52518102	52518125	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.346676216017182	[2]	[3,1]	7	hSpCas9	positive selection	4343442
52520028	52520050	12	-	27760321	OCIAML3	viability	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.02590980332377868	[808,637]	[327,890]	0	hSpCas9	negative selection	4413185
52520058	52520080	12	-	27760321	OCIAML3	viability	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.5441667451884591	[368,285]	[372,367]	6	hSpCas9	negative selection	4413186
52520126	52520148	12	+	27760321	OCIAML3	viability	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	-0.32014799721015763	[870,778]	[470,574]	-3	hSpCas9	negative selection	4413187
52520175	52520197	12	-	27760321	OCIAML3	viability	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.45028303907704886	[647,514]	[627,603]	5	hSpCas9	negative selection	4413188
52520028	52520050	12	-	27760321	OCIAML2	viability	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.5004227404586784	[808,637]	[665,1028]	6	hSpCas9	negative selection	4496648
52520058	52520080	12	-	27760321	OCIAML2	viability	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.79663677632215	[368,285]	[383,552]	9	hSpCas9	negative selection	4496649
52520126	52520148	12	+	27760321	OCIAML2	viability	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.2522926474546465	[870,778]	[682,939]	3	hSpCas9	negative selection	4496650
52520175	52520197	12	-	27760321	OCIAML2	viability	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.3111361088055163	[647,514]	[444,757]	4	hSpCas9	negative selection	4496651
52520028	52520050	12	-	27760321	MV411	viability	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	-0.060523679162677646	[808,637]	[316,661]	0	hSpCas9	negative selection	4580111
52520058	52520080	12	-	27760321	MV411	viability	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.8412892714821795	[368,285]	[204,653]	6	hSpCas9	negative selection	4580112
52520126	52520148	12	+	27760321	MV411	viability	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.5760295933282051	[870,778]	[734,923]	4	hSpCas9	negative selection	4580113
52520175	52520197	12	-	27760321	MV411	viability	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	-0.18376155275920172	[647,514]	[308,375]	-1	hSpCas9	negative selection	4580114
52520028	52520050	12	-	27760321	HL60	viability	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.4744940831115535	[808,637]	[795,836]	6	hSpCas9	negative selection	4663574
52520058	52520080	12	-	27760321	HL60	viability	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.5359478217206263	[368,285]	[322,450]	6	hSpCas9	negative selection	4663575
52520126	52520148	12	+	27760321	HL60	viability	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.2545154271411112	[870,778]	[948,647]	3	hSpCas9	negative selection	4663576
52520175	52520197	12	-	27760321	HL60	viability	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	-0.1728799089386923	[647,514]	[378,460]	-2	hSpCas9	negative selection	4663577
52520028	52520050	12	-	27760321	HT1080	viability	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	2.028359613678055	[637,497]	[1029,805]	9	hSpCas9	negative selection	4747037
52520058	52520080	12	-	27760321	HT1080	viability	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.6054499330908817	[285,222]	[190,113]	3	hSpCas9	negative selection	4747038
52520126	52520148	12	+	27760321	HT1080	viability	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.24265551433546817	[778,607]	[260,398]	1	hSpCas9	negative selection	4747039
52520175	52520197	12	-	27760321	HT1080	viability	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	-1.1580608997306592	[514,401]	[25,142]	-4	hSpCas9	negative selection	4747040
52520028	52520050	12	-	27760321	HT29	viability after 7 days	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.4799054400917462	[637,497]	[820,840,1352]	7	hSpCas9	negative selection	4830500
52520058	52520080	12	-	27760321	HT29	viability after 7 days	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.08818862124917826	[285,222]	[455,178,420]	1	hSpCas9	negative selection	4830501
52520126	52520148	12	+	27760321	HT29	viability after 7 days	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.09036978632744808	[778,607]	[1290,775,831]	1	hSpCas9	negative selection	4830502
52520175	52520197	12	-	27760321	HT29	viability after 7 days	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.043880761105977883	[514,401]	[706,476,650]	0	hSpCas9	negative selection	4830503
52520028	52520050	12	-	27760321	HT29	viability after 25 days	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.6094836109734068	[637,497]	[723,663,1668]	7	hSpCas9	negative selection	4913963
52520058	52520080	12	-	27760321	HT29	viability after 25 days	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.4366516742437278	[285,222]	[296,498,389]	5	hSpCas9	negative selection	4913964
52520126	52520148	12	+	27760321	HT29	viability after 25 days	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.3269132508951892	[778,607]	[811,1119,1067]	3	hSpCas9	negative selection	4913965
52520175	52520197	12	-	27760321	HT29	viability after 25 days	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.2778701209176224	[514,401]	[673,622,601]	3	hSpCas9	negative selection	4913966
52520028	52520050	12	-	27760321	HT29	viability after 22 days	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.5883114568491572	[637,497]	[1008,768,1184]	6	hSpCas9	negative selection	4997426
52520058	52520080	12	-	27760321	HT29	viability after 22 days	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.3040318845491636	[285,222]	[283,419,387]	3	hSpCas9	negative selection	4997427
52520126	52520148	12	+	27760321	HT29	viability after 22 days	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.4475829031196862	[778,607]	[1152,968,1156]	5	hSpCas9	negative selection	4997428
52520175	52520197	12	-	27760321	HT29	viability after 22 days	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.23838482490628854	[514,401]	[820,481,566]	2	hSpCas9	negative selection	4997429
52520028	52520050	12	-	27760321	HT29	viability after 19 days	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.12569728385338708	[637,497]	[586,494,1018]	1	hSpCas9	negative selection	5080889
52520058	52520080	12	-	27760321	HT29	viability after 19 days	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.28052306537072624	[285,222]	[388,293,379]	2	hSpCas9	negative selection	5080890
52520126	52520148	12	+	27760321	HT29	viability after 19 days	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.6227400858383795	[778,607]	[1162,1060,1424]	6	hSpCas9	negative selection	5080891
52520175	52520197	12	-	27760321	HT29	viability after 19 days	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.26074814439869076	[514,401]	[690,680,522]	2	hSpCas9	negative selection	5080892
52520028	52520050	12	-	27760321	HT29	viability after 16 days	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.43189359792633075	[637,497]	[979,637,970]	5	hSpCas9	negative selection	5164352
52520058	52520080	12	-	27760321	HT29	viability after 16 days	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.2221987926236932	[285,222]	[491,386,130]	2	hSpCas9	negative selection	5164353
52520126	52520148	12	+	27760321	HT29	viability after 16 days	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.8635564613719219	[778,607]	[1706,948,1618]	8	hSpCas9	negative selection	5164354
52520175	52520197	12	-	27760321	HT29	viability after 16 days	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.13403998739028994	[514,401]	[841,640,229]	1	hSpCas9	negative selection	5164355
52520028	52520050	12	-	27760321	HT29	viability after 13 days	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.1472170711337405	[637,497]	[647,789,749]	1	hSpCas9	negative selection	5247815
52520058	52520080	12	-	27760321	HT29	viability after 13 days	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.18665023705423317	[285,222]	[339,383,286]	2	hSpCas9	negative selection	5247816
52520126	52520148	12	+	27760321	HT29	viability after 13 days	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.5119523328184009	[778,607]	[1020,1480,951]	6	hSpCas9	negative selection	5247817
52520175	52520197	12	-	27760321	HT29	viability after 13 days	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	0.24425201176931322	[514,401]	[696,786,418]	3	hSpCas9	negative selection	5247818
52520028	52520050	12	-	27760321	HT29	viability after 10 days	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.2921741549407131	[637,497]	[686,828,1082]	4	hSpCas9	negative selection	5331278
52520058	52520080	12	-	27760321	HT29	viability after 10 days	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	0.23966925803718603	[285,222]	[479,399,248]	3	hSpCas9	negative selection	5331279
52520126	52520148	12	+	27760321	HT29	viability after 10 days	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.38479867601814866	[778,607]	[1369,1033,987]	5	hSpCas9	negative selection	5331280
52520175	52520197	12	-	27760321	HT29	viability after 10 days	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	-0.1302707205429532	[514,401]	[565,462,537]	-2	hSpCas9	negative selection	5331281
52520028	52520050	12	-	27760321	MOLM13	viability	TCAGGAACCGGTTTGGTGCTGG	KRT5	ENSG00000186081	0.431400804279109	[808,637]	[493,591]	3	hSpCas9	negative selection	5414741
52520058	52520080	12	-	27760321	MOLM13	viability	GGATATCCATCAGCACTAGTGG	KRT5	ENSG00000186081	-0.16722680750764884	[368,285]	[164,161]	-1	hSpCas9	negative selection	5414742
52520126	52520148	12	+	27760321	MOLM13	viability	CACTCCACAAGCACCCGCAAGG	KRT5	ENSG00000186081	0.42321631562919393	[870,778]	[638,609]	3	hSpCas9	negative selection	5414743
52520175	52520197	12	-	27760321	MOLM13	viability	CCGTGTCCCGGTCCGGGGGTGG	KRT5	ENSG00000186081	-0.5328165201196583	[647,514]	[273,183]	-3	hSpCas9	negative selection	5414744
52520204	52520227	12	+	27661255	K562	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.528695566930558	[503,389]	[293,209]	-7	dCas9-KRAB	negative selection	5489320
52517930	52517953	12	+	27260156	BXPC3	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.012536555487299816	[1851]	[1448,2003,2042,2259]	0	hSpCas9	negative selection	5551645
52517932	52517955	12	-	27260156	BXPC3	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.18422665484353584	[343]	[229,300,415,330]	-4	hSpCas9	negative selection	5551646
52518977	52519000	12	+	27260156	BXPC3	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.22894721890636455	[603]	[695,713,696,869]	5	hSpCas9	negative selection	5551647
52518947	52518970	12	+	27260156	BXPC3	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.4189385471147533	[122]	[147,70,74,83]	-7	hSpCas9	negative selection	5615900
52518115	52518138	12	+	27260156	BXPC3	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.2783526088733912	[24]	[32,47,58,124]	9	hSpCas9	negative selection	5615901
52518102	52518125	12	-	27260156	BXPC3	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.0024038186235149084	[323]	[293,236,480,358]	0	hSpCas9	negative selection	5615902
52517930	52517953	12	+	27260156	A673	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.019319226794170197	[1851]	[2641,2255,1983,2170]	0	hSpCas9	negative selection	5672896
52517932	52517955	12	-	27260156	A673	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.0457469227341985	[343]	[429,409,309,456]	-1	hSpCas9	negative selection	5672897
52518977	52519000	12	+	27260156	A673	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.23373085882785033	[603]	[1068,730,802,833]	5	hSpCas9	negative selection	5672898
52518947	52518970	12	+	27260156	A673	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.34412915218422	[122]	[113,92,101,158]	-7	hSpCas9	negative selection	5737151
52518115	52518138	12	+	27260156	A673	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.9220594218006815	[24]	[56,44,33,93]	9	hSpCas9	negative selection	5737152
52518102	52518125	12	-	27260156	A673	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.1843522846634027	[323]	[494,428,409,439]	4	hSpCas9	negative selection	5737153
52517930	52517953	12	+	27260156	A375	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.08905328880158891	[1851]	[1950,2294,2507,1475]	-1	hSpCas9	negative selection	5794147
52517932	52517955	12	-	27260156	A375	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.26052768350699107	[343]	[366,708,579,317]	4	hSpCas9	negative selection	5794148
52518977	52519000	12	+	27260156	A375	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.37665538179827435	[603]	[1141,1136,806,639]	5	hSpCas9	negative selection	5794149
52518947	52518970	12	+	27260156	A375	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.22988004076188906	[122]	[75,57,156,181]	-3	hSpCas9	negative selection	5858402
52518115	52518138	12	+	27260156	A375	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.31490701724817205	[24]	[41,40,27,34]	4	hSpCas9	negative selection	5858403
52518102	52518125	12	-	27260156	A375	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.16255335005986166	[323]	[399,284,479,498]	2	hSpCas9	negative selection	5858404
52517930	52517953	12	+	27260156	COLO741	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.14190128516457423	[1851]	[2806,2786,2274]	3	hSpCas9	negative selection	5915398
52517932	52517955	12	-	27260156	COLO741	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.07044889516437147	[343]	[512,405,348]	-1	hSpCas9	negative selection	5915399
52518977	52519000	12	+	27260156	COLO741	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.07730404628601728	[603]	[966,860,638]	1	hSpCas9	negative selection	5915400
52518947	52518970	12	+	27260156	COLO741	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.5713472738161798	[122]	[70,106,133]	-8	hSpCas9	negative selection	5979653
52518115	52518138	12	+	27260156	COLO741	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.1676307900651244	[24]	[44,13,147]	9	hSpCas9	negative selection	5979654
52518102	52518125	12	-	27260156	COLO741	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.0299540381146427	[323]	[432,465,324]	0	hSpCas9	negative selection	5979655
52517930	52517953	12	+	27260156	CAL120	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.18781421034865353	[1851]	[2141,2094,1852]	-3	hSpCas9	negative selection	6036649
52517932	52517955	12	-	27260156	CAL120	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.21553460778887534	[343]	[695,558,269]	3	hSpCas9	negative selection	6036650
52518977	52519000	12	+	27260156	CAL120	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.6076673652859772	[603]	[1134,1104,1192]	8	hSpCas9	negative selection	6036651
52518947	52518970	12	+	27260156	CAL120	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-1.5551668253699407	[122]	[54,67,33]	-9	hSpCas9	negative selection	6100904
52518115	52518138	12	+	27260156	CAL120	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.6857449329670882	[24]	[19,42,81]	8	hSpCas9	negative selection	6100905
52518102	52518125	12	-	27260156	CAL120	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.09460946812053506	[323]	[447,361,333]	-1	hSpCas9	negative selection	6100906
52517930	52517953	12	+	27260156	CADOES1	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.04702086078632983	[1851]	[1735,1978,1768,1628]	0	hSpCas9	negative selection	6157900
52517932	52517955	12	-	27260156	CADOES1	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.28299477632271675	[343]	[355,369,368,464]	5	hSpCas9	negative selection	6157901
52518977	52519000	12	+	27260156	CADOES1	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.1491857900067755	[603]	[664,643,502,681]	2	hSpCas9	negative selection	6157902
52518947	52518970	12	+	27260156	CADOES1	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.5072218101199919	[122]	[115,80,40,83]	-7	hSpCas9	negative selection	6222155
52518115	52518138	12	+	27260156	CADOES1	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.3814403218918807	[24]	[58,82,48,50]	9	hSpCas9	negative selection	6222156
52518102	52518125	12	-	27260156	CADOES1	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.232340148043504	[323]	[265,470,285,394]	4	hSpCas9	negative selection	6222157
52517930	52517953	12	+	27260156	EWS502	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.07514365028653613	[1851]	[1864,1736,2179,2549]	1	hSpCas9	negative selection	6279151
52517932	52517955	12	-	27260156	EWS502	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.16639622801811282	[343]	[333,279,304,382]	-3	hSpCas9	negative selection	6279152
52518977	52519000	12	+	27260156	EWS502	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.07121125199993716	[603]	[686,539,693,498]	-1	hSpCas9	negative selection	6279153
52518947	52518970	12	+	27260156	EWS502	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.17994826299579714	[122]	[93,22,211,139]	-3	hSpCas9	negative selection	6343406
52518115	52518138	12	+	27260156	EWS502	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.3203395143332473	[24]	[46,67,129,18]	9	hSpCas9	negative selection	6343407
52518102	52518125	12	-	27260156	EWS502	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.16102693005993823	[323]	[374,454,308,391]	3	hSpCas9	negative selection	6343408
52517930	52517953	12	+	27260156	EW8	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.09592959751996566	[1851]	[1655,1269,1395,1319]	-2	hSpCas9	negative selection	6400402
52517932	52517955	12	-	27260156	EW8	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.044525450292208224	[343]	[302,309,206,274]	-1	hSpCas9	negative selection	6400403
52518977	52519000	12	+	27260156	EW8	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.17637327143945153	[603]	[611,665,435,523]	3	hSpCas9	negative selection	6400404
52518947	52518970	12	+	27260156	EW8	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.9471361450787721	[122]	[31,45,59,64]	-9	hSpCas9	negative selection	6464657
52518115	52518138	12	+	27260156	EW8	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.5700177415199175	[24]	[5,27,44,35]	8	hSpCas9	negative selection	6464658
52518102	52518125	12	-	27260156	EW8	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.19106427261823972	[323]	[239,489,238,233]	3	hSpCas9	negative selection	6464659
52517930	52517953	12	+	27260156	CORL105	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.2890895076371589	[1851]	[2433,2427,3231,2589]	5	hSpCas9	negative selection	6521653
52517932	52517955	12	-	27260156	CORL105	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.017450362056614044	[343]	[461,336,541,313]	0	hSpCas9	negative selection	6521654
52518977	52519000	12	+	27260156	CORL105	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.2762992309273364	[603]	[712,842,1163,748]	5	hSpCas9	negative selection	6521655
52518947	52518970	12	+	27260156	CORL105	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.5895339639788495	[122]	[91,25,153,120]	-8	hSpCas9	negative selection	6585908
52518115	52518138	12	+	27260156	CORL105	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.21065410383860872	[24]	[26,34,38,34]	4	hSpCas9	negative selection	6585909
52518102	52518125	12	-	27260156	CORL105	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.16118220908193698	[323]	[375,366,558,414]	3	hSpCas9	negative selection	6585910
52517930	52517953	12	+	27260156	HS294T	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.19968074824289128	[1851]	[985,663,819,802]	2	hSpCas9	negative selection	6642904
52517932	52517955	12	-	27260156	HS294T	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.18879033745699225	[343]	[115,106,135,105]	-3	hSpCas9	negative selection	6642905
52518977	52519000	12	+	27260156	HS294T	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.12343009196243704	[603]	[173,244,295,320]	1	hSpCas9	negative selection	6642906
52518947	52518970	12	+	27260156	HS294T	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.11180527292280096	[122]	[84,13,69,30]	1	hSpCas9	negative selection	6707159
52518115	52518138	12	+	27260156	HS294T	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.4039083724784853	[24]	[6,18,9,15]	5	hSpCas9	negative selection	6707160
52518102	52518125	12	-	27260156	HS294T	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.2352149940321705	[323]	[56,65,224,78]	-3	hSpCas9	negative selection	6707161
52517930	52517953	12	+	27260156	HCC44	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.08357414871706648	[1851]	[2836,2160,2534,1470]	1	hSpCas9	negative selection	6764155
52517932	52517955	12	-	27260156	HCC44	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.07200866248257265	[343]	[387,317,575,390]	1	hSpCas9	negative selection	6764156
52518977	52519000	12	+	27260156	HCC44	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.22826296700981635	[603]	[1047,617,866,723]	3	hSpCas9	negative selection	6764157
52518947	52518970	12	+	27260156	HCC44	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.9814864344358862	[122]	[80,28,100,81]	-8	hSpCas9	negative selection	6828410
52518115	52518138	12	+	27260156	HCC44	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.5515512760443873	[24]	[60,49,46,9]	8	hSpCas9	negative selection	6828411
52518102	52518125	12	-	27260156	HCC44	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.27929599544608463	[323]	[587,301,375,527]	4	hSpCas9	negative selection	6828412
52517930	52517953	12	+	27260156	G402	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.22159382783918358	[1851]	[2694,2279,2891,2649]	2	hSpCas9	negative selection	6885406
52517932	52517955	12	-	27260156	G402	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.5589399793191095	[343]	[984,337,762,430]	7	hSpCas9	negative selection	6885407
52518977	52519000	12	+	27260156	G402	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.3872692016212907	[603]	[899,1488,683,807]	5	hSpCas9	negative selection	6885408
52518947	52518970	12	+	27260156	G402	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.09911460113346027	[122]	[85,27,202,299]	1	hSpCas9	negative selection	6949661
52518115	52518138	12	+	27260156	G402	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.21852932560653926	[24]	[50,45,39,8]	2	hSpCas9	negative selection	6949662
52518102	52518125	12	-	27260156	G402	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.43606889795873793	[323]	[402,345,963,400]	5	hSpCas9	negative selection	6949663
52517930	52517953	12	+	27260156	L33	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.020260509104139457	[1851]	[1879,729,1268,1832]	0	hSpCas9	negative selection	7006657
52517932	52517955	12	-	27260156	L33	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.15845934407459394	[343]	[362,134,165,274]	-4	hSpCas9	negative selection	7006658
52518977	52519000	12	+	27260156	L33	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.10550304647708314	[603]	[581,263,317,512]	-2	hSpCas9	negative selection	7006659
52518947	52518970	12	+	27260156	L33	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.48092331936692956	[122]	[91,39,60,65]	-8	hSpCas9	negative selection	7070912
52518115	52518138	12	+	27260156	L33	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.7508692119262363	[24]	[31,31,22,21]	9	hSpCas9	negative selection	7070913
52518102	52518125	12	-	27260156	L33	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.16895904675669327	[323]	[341,93,187,280]	-4	hSpCas9	negative selection	7070914
52517930	52517953	12	+	27260156	K562	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.06893502397535411	[1851]	[2135,1180,1761,1245]	-1	hSpCas9	negative selection	7127908
52517932	52517955	12	-	27260156	K562	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.0836753482410526	[343]	[285,211,474,185]	-1	hSpCas9	negative selection	7127909
52518977	52519000	12	+	27260156	K562	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.4040467525566797	[603]	[1066,623,686,504]	5	hSpCas9	negative selection	7127910
52518947	52518970	12	+	27260156	K562	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-1.9362198923928555	[122]	[33,43,15,21]	-9	hSpCas9	negative selection	7192163
52518115	52518138	12	+	27260156	K562	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.0371608758712028	[24]	[18,29,18,103]	9	hSpCas9	negative selection	7192164
52518102	52518125	12	-	27260156	K562	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.9753735631651965	[323]	[483,546,878,364]	9	hSpCas9	negative selection	7192165
52517930	52517953	12	+	27260156	HT29	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.18166120282200304	[1851]	[2586,3058,2642,2018]	3	hSpCas9	negative selection	7249159
52517932	52517955	12	-	27260156	HT29	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.049293999132489885	[343]	[540,476,317,406]	0	hSpCas9	negative selection	7249160
52518977	52519000	12	+	27260156	HT29	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.2223486271549599	[603]	[985,843,805,799]	4	hSpCas9	negative selection	7249161
52518947	52518970	12	+	27260156	HT29	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.2395873101625423	[122]	[214,161,183,148]	5	hSpCas9	negative selection	7313414
52518115	52518138	12	+	27260156	HT29	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.1450932738335973	[24]	[82,55,47,79]	9	hSpCas9	negative selection	7313415
52518102	52518125	12	-	27260156	HT29	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.3683819085236696	[323]	[525,429,688,393]	7	hSpCas9	negative selection	7313416
52517930	52517953	12	+	27260156	MHHES1	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.14953025076408522	[1851]	[2285,2522,2610,1898]	2	hSpCas9	negative selection	7370410
52517932	52517955	12	-	27260156	MHHES1	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.08391848130041696	[343]	[596,312,379,365]	1	hSpCas9	negative selection	7370411
52518977	52519000	12	+	27260156	MHHES1	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.31862249710772167	[603]	[838,1184,680,728]	6	hSpCas9	negative selection	7370412
52518947	52518970	12	+	27260156	MHHES1	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-1.0954331346168384	[122]	[136,89,49,5]	-9	hSpCas9	negative selection	7434665
52518115	52518138	12	+	27260156	MHHES1	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.25161281964635407	[24]	[50,29,55,4]	4	hSpCas9	negative selection	7434666
52518102	52518125	12	-	27260156	MHHES1	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.20557406305623543	[323]	[551,391,337,406]	4	hSpCas9	negative selection	7434667
52517930	52517953	12	+	27260156	MEWO	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.13838910446730357	[1851]	[2173,1819,1778]	3	hSpCas9	negative selection	7491661
52517932	52517955	12	-	27260156	MEWO	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.16959619215814548	[343]	[416,225,240]	-4	hSpCas9	negative selection	7491662
52518977	52519000	12	+	27260156	MEWO	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.27658206847088435	[603]	[862,665,558]	6	hSpCas9	negative selection	7491663
52518947	52518970	12	+	27260156	MEWO	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.371911438257428	[122]	[33,111,109]	-7	hSpCas9	negative selection	7555916
52518115	52518138	12	+	27260156	MEWO	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.3155260598535108	[24]	[31,5,20]	-6	hSpCas9	negative selection	7555917
52518102	52518125	12	-	27260156	MEWO	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.2444247836145721	[323]	[339,231,211]	-5	hSpCas9	negative selection	7555918
52517930	52517953	12	+	27260156	LNCAPCLONEFGC	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.026624698989204054	[1851]	[1694,1842,1716,1571]	0	hSpCas9	negative selection	7612912
52517932	52517955	12	-	27260156	LNCAPCLONEFGC	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.13971476643349107	[343]	[343,276,495,282]	2	hSpCas9	negative selection	7612913
52518977	52519000	12	+	27260156	LNCAPCLONEFGC	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.3186707059459592	[603]	[555,675,756,753]	5	hSpCas9	negative selection	7612914
52518947	52518970	12	+	27260156	LNCAPCLONEFGC	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.6730734885910548	[122]	[76,72,95,36]	-7	hSpCas9	negative selection	7677167
52518115	52518138	12	+	27260156	LNCAPCLONEFGC	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.1027880450034124	[24]	[53,38,81,24]	9	hSpCas9	negative selection	7677168
52518102	52518125	12	-	27260156	LNCAPCLONEFGC	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.3228187342580673	[323]	[343,374,460,301]	5	hSpCas9	negative selection	7677169
52517930	52517953	12	+	27260156	PANC0327	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.12430202359426801	[1851]	[1702,1210,1434,1741]	-2	hSpCas9	negative selection	7734163
52517932	52517955	12	-	27260156	PANC0327	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.33857738034961854	[343]	[364,286,598,305]	5	hSpCas9	negative selection	7734164
52518977	52519000	12	+	27260156	PANC0327	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.16599682994214066	[603]	[736,317,485,913]	2	hSpCas9	negative selection	7734165
52518947	52518970	12	+	27260156	PANC0327	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-1.1476980681992064	[122]	[65,45,28,57]	-8	hSpCas9	negative selection	7798418
52518115	52518138	12	+	27260156	PANC0327	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.2414109564511229	[24]	[75,36,78,21]	9	hSpCas9	negative selection	7798419
52518102	52518125	12	-	27260156	PANC0327	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.6992803504901302	[323]	[260,144,162,150]	-7	hSpCas9	negative selection	7798420
52517930	52517953	12	+	27260156	NCIH2009	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.08197100986344652	[1851]	[3482,2180,2704]	1	hSpCas9	negative selection	7855414
52517932	52517955	12	-	27260156	NCIH2009	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.24031332300013886	[343]	[513,412,313]	-3	hSpCas9	negative selection	7855415
52518977	52519000	12	+	27260156	NCIH2009	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.32629635934042295	[603]	[1599,753,930]	4	hSpCas9	negative selection	7855416
52518947	52518970	12	+	27260156	NCIH2009	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.27286072578841836	[122]	[67,185,156]	-4	hSpCas9	negative selection	7919669
52518115	52518138	12	+	27260156	NCIH2009	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.064637331494679	[24]	[74,41,102]	9	hSpCas9	negative selection	7919670
52518102	52518125	12	-	27260156	NCIH2009	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.08711089241896286	[323]	[474,502,307]	-1	hSpCas9	negative selection	7919671
52517930	52517953	12	+	27260156	NCIH1373	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.35002297329787857	[1851]	[2232,1566,1106,450]	-3	hSpCas9	negative selection	7976665
52517932	52517955	12	-	27260156	NCIH1373	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.704226981899869	[343]	[312,185,311,37]	-6	hSpCas9	negative selection	7976666
52518977	52519000	12	+	27260156	NCIH1373	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.4993709529788903	[603]	[1409,316,1291,245]	5	hSpCas9	negative selection	7976667
52518947	52518970	12	+	27260156	NCIH1373	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.7176111485929448	[122]	[86,68,68,29]	-6	hSpCas9	negative selection	8040920
52518115	52518138	12	+	27260156	NCIH1373	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.692804191955819	[24]	[15,12,24,3]	-6	hSpCas9	negative selection	8040921
52518102	52518125	12	-	27260156	NCIH1373	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.15816614203174628	[323]	[420,412,105,97]	-1	hSpCas9	negative selection	8040922
52517930	52517953	12	+	27260156	PATU8902	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.4086504198843737	[1851]	[1441,2113,1340,3169]	-4	hSpCas9	negative selection	8097916
52517932	52517955	12	-	27260156	PATU8902	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.1845552080794025	[343]	[821,385,388,621]	1	hSpCas9	negative selection	8097917
52518977	52519000	12	+	27260156	PATU8902	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.611295901088253	[603]	[1171,1665,1066,1283]	6	hSpCas9	negative selection	8097918
52518947	52518970	12	+	27260156	PATU8902	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-1.9061963420844021	[122]	[28,6,10,157]	-9	hSpCas9	negative selection	8162171
52518115	52518138	12	+	27260156	PATU8902	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	-0.1427228123330977	[24]	[3,35,64,9]	-1	hSpCas9	negative selection	8162172
52518102	52518125	12	-	27260156	PATU8902	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.41588537711405693	[323]	[1076,315,621,344]	4	hSpCas9	negative selection	8162173
52517930	52517953	12	+	27260156	PANC1	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.39587112061989616	[1851]	[1904,2320,2218,1964]	6	hSpCas9	negative selection	8219167
52517932	52517955	12	-	27260156	PANC1	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.31451954382292846	[343]	[385,440,371,291]	5	hSpCas9	negative selection	8219168
52518977	52519000	12	+	27260156	PANC1	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.2173641585983696	[603]	[633,452,664,616]	3	hSpCas9	negative selection	8219169
52518947	52518970	12	+	27260156	PANC1	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.3404926226955505	[122]	[45,174,55,75]	-5	hSpCas9	negative selection	8283422
52518115	52518138	12	+	27260156	PANC1	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.9336457429351239	[24]	[17,5,97,35]	9	hSpCas9	negative selection	8283423
52518102	52518125	12	-	27260156	PANC1	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.26394917479780944	[323]	[238,391,258,436]	4	hSpCas9	negative selection	8283424
52517930	52517953	12	+	27260156	PANC0813	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.09785989886517954	[1851]	[2160,2079,2687,2363]	1	hSpCas9	negative selection	8340418
52517932	52517955	12	-	27260156	PANC0813	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.2987867094513774	[343]	[394,392,306,229]	-5	hSpCas9	negative selection	8340419
52518977	52519000	12	+	27260156	PANC0813	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.15418114651407971	[603]	[909,624,942,695]	2	hSpCas9	negative selection	8340420
52518947	52518970	12	+	27260156	PANC0813	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.4418916762656102	[122]	[74,223,35,87]	-6	hSpCas9	negative selection	8404673
52518115	52518138	12	+	27260156	PANC0813	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.1099849044851346	[24]	[98,131,9,17]	9	hSpCas9	negative selection	8404674
52518102	52518125	12	-	27260156	PANC0813	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.21780133526146445	[323]	[458,358,380,564]	3	hSpCas9	negative selection	8404675
52517930	52517953	12	+	27260156	RDES	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.30592932666759487	[1851]	[1532,1682,1650,2062]	-5	hSpCas9	negative selection	8461669
52517932	52517955	12	-	27260156	RDES	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.4518673069336423	[343]	[284,281,201,391]	-6	hSpCas9	negative selection	8461670
52518977	52519000	12	+	27260156	RDES	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.17070597065388865	[603]	[573,749,803,1069]	2	hSpCas9	negative selection	8461671
52518947	52518970	12	+	27260156	RDES	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.2777611329399916	[122]	[414,104,33,50]	4	hSpCas9	negative selection	8525924
52518115	52518138	12	+	27260156	RDES	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.8793489928833154	[24]	[49,33,77,50]	9	hSpCas9	negative selection	8525925
52518102	52518125	12	-	27260156	RDES	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.26483997874113413	[323]	[295,585,421,499]	4	hSpCas9	negative selection	8525926
52517930	52517953	12	+	27260156	PC3	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.24196030906343702	[1851]	[1426,2075,3243,2529]	5	hSpCas9	negative selection	8582920
52517932	52517955	12	-	27260156	PC3	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.03913238261340146	[343]	[197,396,393,474]	0	hSpCas9	negative selection	8582921
52518977	52519000	12	+	27260156	PC3	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.49083781148804445	[603]	[473,823,1497,935]	8	hSpCas9	negative selection	8582922
52518947	52518970	12	+	27260156	PC3	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.20999992877690277	[122]	[122,106,204,148]	4	hSpCas9	negative selection	8647175
52518115	52518138	12	+	27260156	PC3	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.8454381870992815	[24]	[3,16,39,138]	9	hSpCas9	negative selection	8647176
52518102	52518125	12	-	27260156	PC3	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.27271950047522225	[323]	[296,280,667,426]	6	hSpCas9	negative selection	8647177
52517930	52517953	12	+	27260156	PATU8988T	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.12942843089167888	[1851]	[2233,2004,1785,1798]	2	hSpCas9	negative selection	8704171
52517932	52517955	12	-	27260156	PATU8988T	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.19425251802804616	[343]	[393,422,317,391]	3	hSpCas9	negative selection	8704172
52518977	52519000	12	+	27260156	PATU8988T	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.7751441313151428	[603]	[1346,906,875,845]	9	hSpCas9	negative selection	8704173
52518947	52518970	12	+	27260156	PATU8988T	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.2533377773288832	[122]	[17,205,45,142]	-4	hSpCas9	negative selection	8768426
52518115	52518138	12	+	27260156	PATU8988T	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.3267186234308799	[24]	[18,8,67,21]	5	hSpCas9	negative selection	8768427
52518102	52518125	12	-	27260156	PATU8988T	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.39065545469213403	[323]	[177,222,348,198]	-6	hSpCas9	negative selection	8768428
52517930	52517953	12	+	27260156	T47D	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.0746492060111208	[1851]	[2377,2269,2209,2229]	1	hSpCas9	negative selection	8825422
52517932	52517955	12	-	27260156	T47D	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.06953970469902016	[343]	[366,336,389,438]	-1	hSpCas9	negative selection	8825423
52518977	52519000	12	+	27260156	T47D	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.051206743135183475	[603]	[630,681,622,783]	-1	hSpCas9	negative selection	8825424
52518947	52518970	12	+	27260156	T47D	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.6764186802287866	[122]	[69,109,82,93]	-8	hSpCas9	negative selection	8889677
52518115	52518138	12	+	27260156	T47D	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.6486665055943948	[24]	[50,43,38,48]	9	hSpCas9	negative selection	8889678
52518102	52518125	12	-	27260156	T47D	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.13271955943972163	[323]	[429,369,374,486]	3	hSpCas9	negative selection	8889679
52517930	52517953	12	+	27260156	SU8686	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.09242624794020915	[1851]	[1819,1722,2140,2226]	1	hSpCas9	negative selection	8946673
52517932	52517955	12	-	27260156	SU8686	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.09321858133248584	[343]	[250,241,455,354]	-2	hSpCas9	negative selection	8946674
52518977	52519000	12	+	27260156	SU8686	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.6107295539942752	[603]	[863,674,764,1469]	8	hSpCas9	negative selection	8946675
52518947	52518970	12	+	27260156	SU8686	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.9993975406355129	[122]	[36,48,45,125]	-8	hSpCas9	negative selection	9010928
52518115	52518138	12	+	27260156	SU8686	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.4946360031247474	[24]	[27,26,18,72]	8	hSpCas9	negative selection	9010929
52518102	52518125	12	-	27260156	SU8686	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	-0.2970992056670776	[323]	[241,197,211,427]	-5	hSpCas9	negative selection	9010930
52517930	52517953	12	+	27260156	SKES1	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.049575141384770705	[1851]	[2230,2246,1578,1686]	1	hSpCas9	negative selection	9067924
52517932	52517955	12	-	27260156	SKES1	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.08249170252734939	[343]	[264,345,362,313]	-2	hSpCas9	negative selection	9067925
52518977	52519000	12	+	27260156	SKES1	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	-0.008761458968493507	[603]	[642,814,592,394]	0	hSpCas9	negative selection	9067926
52518947	52518970	12	+	27260156	SKES1	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.6801119170014571	[122]	[85,136,57,37]	-9	hSpCas9	negative selection	9132179
52518115	52518138	12	+	27260156	SKES1	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.37432426121863	[24]	[112,29,56,60]	9	hSpCas9	negative selection	9132180
52518102	52518125	12	-	27260156	SKES1	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.13834166436350348	[323]	[373,312,401,329]	3	hSpCas9	negative selection	9132181
52517930	52517953	12	+	27260156	TOV112D	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.07541875553198563	[1851]	[2007,2642,1839,1509]	1	hSpCas9	negative selection	9189175
52517932	52517955	12	-	27260156	TOV112D	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.005818140808218075	[343]	[414,530,305,186]	0	hSpCas9	negative selection	9189176
52518977	52519000	12	+	27260156	TOV112D	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.15454500475001892	[603]	[960,634,726,391]	3	hSpCas9	negative selection	9189177
52518947	52518970	12	+	27260156	TOV112D	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.4882922700116805	[122]	[92,98,62,98]	-7	hSpCas9	negative selection	9253430
52518115	52518138	12	+	27260156	TOV112D	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.39558848909163435	[24]	[30,66,11,29]	7	hSpCas9	negative selection	9253431
52518102	52518125	12	-	27260156	TOV112D	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.03979377762793879	[323]	[461,438,225,245]	0	hSpCas9	negative selection	9253432
52517930	52517953	12	+	27260156	TC71	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	-0.025633729000215988	[1851]	[1886,1866,1860,2205]	0	hSpCas9	negative selection	9310426
52517932	52517955	12	-	27260156	TC71	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	0.31376947442730824	[343]	[312,500,502,521]	7	hSpCas9	negative selection	9310427
52518977	52519000	12	+	27260156	TC71	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.12542276150720083	[603]	[752,667,738,659]	3	hSpCas9	negative selection	9310428
52518947	52518970	12	+	27260156	TC71	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	0.03571458924542714	[122]	[81,179,178,96]	0	hSpCas9	negative selection	9374681
52518115	52518138	12	+	27260156	TC71	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	0.6878369276492533	[24]	[56,20,51,41]	9	hSpCas9	negative selection	9374682
52518102	52518125	12	-	27260156	TC71	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.09539111699951935	[323]	[420,325,456,269]	2	hSpCas9	negative selection	9374683
52517930	52517953	12	+	27260156	TC32	viability	ATCCATCAGTGCATCAACCTTGG	KRT5	ENSG00000186081	0.03874973005980986	[1851]	[1829,1218,2327,1982]	0	hSpCas9	negative selection	9431677
52517932	52517955	12	-	27260156	TC32	viability	GGCCAAGGTTGATGCACTGATGG	KRT5	ENSG00000186081	-0.2310728095010608	[343]	[289,133,434,308]	-4	hSpCas9	negative selection	9431678
52518977	52519000	12	+	27260156	TC32	viability	TGTTTCTCAGCTCTGAGTCCAGG	KRT5	ENSG00000186081	0.27643312394835	[603]	[604,426,1052,805]	5	hSpCas9	negative selection	9431679
52518947	52518970	12	+	27260156	TC32	viability	TGTTCTTGAAGTCTTCCACCAGG	KRT5	ENSG00000186081	-0.7671425798513698	[122]	[42,45,149,53]	-9	hSpCas9	negative selection	9495932
52518115	52518138	12	+	27260156	TC32	viability	CACAAACTCATTCTCAGCAGTGG	KRT5	ENSG00000186081	1.1156956858314282	[24]	[46,25,98,46]	9	hSpCas9	negative selection	9495933
52518102	52518125	12	-	27260156	TC32	viability	TGAGTTTGTGATGCTGAAGAAGG	KRT5	ENSG00000186081	0.12984864598617657	[323]	[370,144,558,345]	2	hSpCas9	negative selection	9495934
52514945	52514968	12	+	27869803	HPAFII	viability after 27 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-1.2635610329763045	[136]	[53,9,NaN]	-7	hSpCas9	negative selection	9547241
52515036	52515059	12	-	27869803	HPAFII	viability after 27 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.6002056515902756	[578]	[503,425,NaN]	5	hSpCas9	negative selection	9547242
52520204	52520227	12	+	27869803	HPAFII	viability after 27 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	0.4715474122002711	[105]	[19,124,NaN]	4	hSpCas9	negative selection	9547243
52520260	52520283	12	-	27869803	HPAFII	viability after 27 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.8755415789792651	[407]	[404,383,NaN]	7	hSpCas9	negative selection	9547244
52520262	52520285	12	-	27869803	HPAFII	viability after 27 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.0692171589715409	[578]	[368,277,NaN]	0	hSpCas9	negative selection	9547245
52520276	52520299	12	+	27869803	HPAFII	viability after 27 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.3772310275353782	[357]	[115,168,NaN]	-3	hSpCas9	negative selection	9547246
52514945	52514968	12	+	27869803	HPAFII	viability after 15 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.579462959018577	[136]	[100,96,NaN]	-6	hSpCas9	negative selection	9629690
52515036	52515059	12	-	27869803	HPAFII	viability after 15 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.2371481288297641	[578]	[1013,558,NaN]	2	hSpCas9	negative selection	9629691
52520204	52520227	12	+	27869803	HPAFII	viability after 15 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.5934562387095843	[105]	[93,63,NaN]	-6	hSpCas9	negative selection	9629692
52520260	52520283	12	-	27869803	HPAFII	viability after 15 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.5414404100387935	[407]	[697,600,NaN]	6	hSpCas9	negative selection	9629693
52520262	52520285	12	-	27869803	HPAFII	viability after 15 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.1273409902845306	[578]	[1106,413,NaN]	1	hSpCas9	negative selection	9629694
52520276	52520299	12	+	27869803	HPAFII	viability after 15 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.01407597399571714	[357]	[565,265,NaN]	0	hSpCas9	negative selection	9629695
52514945	52514968	12	+	27869803	ASPC1	viability after 36 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.10192406056641334	[256]	[43,121,79]	-1	hSpCas9	negative selection	9712139
52515036	52515059	12	-	27869803	ASPC1	viability after 36 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.5263090749806839	[1249]	[725,638,544]	5	hSpCas9	negative selection	9712140
52520204	52520227	12	+	27869803	ASPC1	viability after 36 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.6228102433214502	[267]	[21,108,48]	-6	hSpCas9	negative selection	9712141
52520260	52520283	12	-	27869803	ASPC1	viability after 36 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.419500088131067	[1038]	[620,306,525]	4	hSpCas9	negative selection	9712142
52520262	52520285	12	-	27869803	ASPC1	viability after 36 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.22387102736594877	[1738]	[671,488,901]	2	hSpCas9	negative selection	9712143
52520276	52520299	12	+	27869803	ASPC1	viability after 36 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	-0.018335455435608994	[1195]	[606,409,272]	0	hSpCas9	negative selection	9712144
52514945	52514968	12	+	27869803	PATU8988S	viability after 35 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	0.3085071828168975	[321]	[206,113,NaN]	3	hSpCas9	negative selection	9794588
52515036	52515059	12	-	27869803	PATU8988S	viability after 35 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.1770416215730093	[1155]	[467,584,NaN]	2	hSpCas9	negative selection	9794589
52520204	52520227	12	+	27869803	PATU8988S	viability after 35 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-3.1055256689134603	[320]	[23,5,NaN]	-9	hSpCas9	negative selection	9794590
52520260	52520283	12	-	27869803	PATU8988S	viability after 35 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.10006437176071614	[936]	[395,412,NaN]	1	hSpCas9	negative selection	9794591
52520262	52520285	12	-	27869803	PATU8988S	viability after 35 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.3508710148533001	[1348]	[867,516,NaN]	4	hSpCas9	negative selection	9794592
52520276	52520299	12	+	27869803	PATU8988S	viability after 35 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.04540819010206176	[1108]	[430,490,NaN]	0	hSpCas9	negative selection	9794593
52514945	52514968	12	+	27869803	PATU8988S	viability after 31 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.04548604768477271	[321]	[174,59,NaN]	0	hSpCas9	negative selection	9877037
52515036	52515059	12	-	27869803	PATU8988S	viability after 31 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.6022664997451592	[1155]	[525,920,NaN]	7	hSpCas9	negative selection	9877038
52520204	52520227	12	+	27869803	PATU8988S	viability after 31 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.126050913503967	[320]	[77,33,NaN]	-8	hSpCas9	negative selection	9877039
52520260	52520283	12	-	27869803	PATU8988S	viability after 31 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.05652219408267334	[936]	[344,443,NaN]	0	hSpCas9	negative selection	9877040
52520262	52520285	12	-	27869803	PATU8988S	viability after 31 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.36841381160063724	[1348]	[689,699,NaN]	4	hSpCas9	negative selection	9877041
52520276	52520299	12	+	27869803	PATU8988S	viability after 31 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.08244519083118607	[1108]	[337,633,NaN]	1	hSpCas9	negative selection	9877042
52514945	52514968	12	+	27869803	HPAFII	viability after 35 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.592629523557855	[136]	[29,63,NaN]	-4	hSpCas9	negative selection	9959486
52515036	52515059	12	-	27869803	HPAFII	viability after 35 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.7555965687775044	[578]	[484,505,NaN]	5	hSpCas9	negative selection	9959487
52520204	52520227	12	+	27869803	HPAFII	viability after 35 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.4156590002836358	[105]	[27,53,NaN]	-3	hSpCas9	negative selection	9959488
52520260	52520283	12	-	27869803	HPAFII	viability after 35 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.998749622784419	[407]	[360,470,NaN]	6	hSpCas9	negative selection	9959489
52520262	52520285	12	-	27869803	HPAFII	viability after 35 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.1661274005504021	[578]	[342,312,NaN]	1	hSpCas9	negative selection	9959490
52520276	52520299	12	+	27869803	HPAFII	viability after 35 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.01285040351775213	[357]	[132,238,NaN]	0	hSpCas9	negative selection	9959491
52514945	52514968	12	+	27869803	HPAFII	viability after 31 days	GCTCTTGAAGCTCTTCCGGGAGG	KRT5	ENSG00000186081	-0.7041642708529604	[136]	[17,78,NaN]	-4	hSpCas9	negative selection	10041935
52515036	52515059	12	-	27869803	HPAFII	viability after 31 days	TTCAGTGCAAGCAGTGGCCGAGG	KRT5	ENSG00000186081	0.17987760589730506	[578]	[224,523,NaN]	1	hSpCas9	negative selection	10041936
52520204	52520227	12	+	27869803	HPAFII	viability after 31 days	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.427176604158245	[105]	[4,86,NaN]	-3	hSpCas9	negative selection	10041937
52520260	52520283	12	-	27869803	HPAFII	viability after 31 days	AAGTGTGTCCTTCCGGAGCGGGG	KRT5	ENSG00000186081	0.8654176985566868	[407]	[297,546,NaN]	6	hSpCas9	negative selection	10041938
52520262	52520285	12	-	27869803	HPAFII	viability after 31 days	TCAAGTGTGTCCTTCCGGAGCGG	KRT5	ENSG00000186081	0.03746371309569008	[578]	[444,211,NaN]	0	hSpCas9	negative selection	10041939
52520276	52520299	12	+	27869803	HPAFII	viability after 31 days	CACACTTGACTGGCGAGACATGG	KRT5	ENSG00000186081	0.10730257871371063	[357]	[158,278,NaN]	0	hSpCas9	negative selection	10041940
52519888	52519911	12	+	28162770	P31FUJ	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-3.3031915323057763	[83]	[9]	-9	hSpCas9	negative selection	10181555
52517169	52517192	12	+	28162770	P31FUJ	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.05036984699049124	[165]	[201]	0	hSpCas9	negative selection	10181556
52519808	52519831	12	-	28162770	P31FUJ	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.017521149669861208	[189]	[225]	0	hSpCas9	negative selection	10181557
52517207	52517230	12	-	28162770	P31FUJ	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-0.10727132233051972	[142]	[155]	-1	hSpCas9	negative selection	10181558
52516692	52516715	12	-	28162770	P31FUJ	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-1.0967406548383505	[90]	[49]	-6	hSpCas9	negative selection	10181559
52520219	52520242	12	+	28162770	P31FUJ	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-1.7802899997168717	[75]	[25]	-8	hSpCas9	negative selection	10181560
52520204	52520227	12	+	28162770	P31FUJ	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.9557382386765267	[306]	[185]	-6	hSpCas9	negative selection	10181561
52520051	52520074	12	+	28162770	P31FUJ	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.8800459552558745	[337]	[730]	8	hSpCas9	negative selection	10181562
52519920	52519943	12	-	28162770	P31FUJ	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.30776617694832403	[186]	[271]	3	hSpCas9	negative selection	10181563
52519013	52519036	12	-	28162770	P31FUJ	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	1.9787019007793332	[18]	[87]	9	hSpCas9	negative selection	10181564
52519888	52519911	12	+	28162770	TF1	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	NaN	[NaN]	[59]	1	hSpCas9	negative selection	10350921
52517169	52517192	12	+	28162770	TF1	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10350922
52519808	52519831	12	-	28162770	TF1	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10350923
52517207	52517230	12	-	28162770	TF1	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	NaN	[NaN]	[233]	1	hSpCas9	negative selection	10350924
52516692	52516715	12	-	28162770	TF1	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	NaN	[NaN]	[39]	1	hSpCas9	negative selection	10350925
52520219	52520242	12	+	28162770	TF1	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	NaN	[NaN]	[8]	1	hSpCas9	negative selection	10350926
52520204	52520227	12	+	28162770	TF1	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	NaN	[NaN]	[22]	1	hSpCas9	negative selection	10350927
52520051	52520074	12	+	28162770	TF1	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	NaN	[NaN]	[334]	1	hSpCas9	negative selection	10350928
52519920	52519943	12	-	28162770	TF1	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	NaN	[NaN]	[246]	1	hSpCas9	negative selection	10350929
52519013	52519036	12	-	28162770	TF1	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10350930
52519888	52519911	12	+	28162770	SKM1	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-1.5382087320214144	[22]	[13]	-7	hSpCas9	negative selection	10520287
52517169	52517192	12	+	28162770	SKM1	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.5590884693335005	[42]	[111]	5	hSpCas9	negative selection	10520288
52519808	52519831	12	-	28162770	SKM1	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.6804986425071777	[47]	[135]	6	hSpCas9	negative selection	10520289
52517207	52517230	12	-	28162770	SKM1	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.31229939368958554	[40]	[89]	3	hSpCas9	negative selection	10520290
52516692	52516715	12	-	28162770	SKM1	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-1.1845717774067137	[35]	[27]	-7	hSpCas9	negative selection	10520291
52520219	52520242	12	+	28162770	SKM1	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-2.000338939280518	[42]	[18]	-8	hSpCas9	negative selection	10520292
52520204	52520227	12	+	28162770	SKM1	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.6414294523801846	[74]	[84]	-5	hSpCas9	negative selection	10520293
52520051	52520074	12	+	28162770	SKM1	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	1.1187590986033185	[86]	[333]	9	hSpCas9	negative selection	10520294
52519920	52519943	12	-	28162770	SKM1	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	-0.029806583135407128	[40]	[70]	0	hSpCas9	negative selection	10520295
52519013	52519036	12	-	28162770	SKM1	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-2.143929792909368	[4]	[1]	-8	hSpCas9	negative selection	10520296
52519888	52519911	12	+	28162770	SKM1	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-1.5382087320214144	[22]	[13]	-7	hSpCas9	negative selection	10689653
52517169	52517192	12	+	28162770	SKM1	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.5590884693335005	[42]	[111]	5	hSpCas9	negative selection	10689654
52519808	52519831	12	-	28162770	SKM1	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.6804986425071777	[47]	[135]	6	hSpCas9	negative selection	10689655
52517207	52517230	12	-	28162770	SKM1	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.31229939368958554	[40]	[89]	3	hSpCas9	negative selection	10689656
52516692	52516715	12	-	28162770	SKM1	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-1.1845717774067137	[35]	[27]	-7	hSpCas9	negative selection	10689657
52520219	52520242	12	+	28162770	SKM1	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-2.000338939280518	[42]	[18]	-8	hSpCas9	negative selection	10689658
52520204	52520227	12	+	28162770	SKM1	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.6414294523801846	[74]	[84]	-5	hSpCas9	negative selection	10689659
52520051	52520074	12	+	28162770	SKM1	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	1.1187590986033185	[86]	[333]	9	hSpCas9	negative selection	10689660
52519920	52519943	12	-	28162770	SKM1	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	-0.029806583135407128	[40]	[70]	0	hSpCas9	negative selection	10689661
52519013	52519036	12	-	28162770	SKM1	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-2.143929792909368	[4]	[1]	-8	hSpCas9	negative selection	10689662
52519888	52519911	12	+	28162770	PL21	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.870249713402078	[104]	[24]	-5	hSpCas9	negative selection	10859019
52517169	52517192	12	+	28162770	PL21	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	-1.0546742845395052	[104]	[21]	-6	hSpCas9	negative selection	10859020
52519808	52519831	12	-	28162770	PL21	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.4028243644082823	[178]	[102]	3	hSpCas9	negative selection	10859021
52517207	52517230	12	-	28162770	PL21	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-1.436169766232056	[142]	[22]	-7	hSpCas9	negative selection	10859022
52516692	52516715	12	-	28162770	PL21	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-1.3057513152406373	[141]	[24]	-7	hSpCas9	negative selection	10859023
52520219	52520242	12	+	28162770	PL21	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.7184327861668338	[154]	[40]	-5	hSpCas9	negative selection	10859024
52520204	52520227	12	+	28162770	PL21	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	0.5371746017668908	[170]	[107]	5	hSpCas9	negative selection	10859025
52520051	52520074	12	+	28162770	PL21	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	1.2271066620895894	[264]	[269]	8	hSpCas9	negative selection	10859026
52519920	52519943	12	-	28162770	PL21	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	-1.0683492214365815	[105]	[21]	-6	hSpCas9	negative selection	10859027
52519013	52519036	12	-	28162770	PL21	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	1.5562834247145954	[24]	[31]	9	hSpCas9	negative selection	10859028
52519888	52519911	12	+	28162770	P31FUJ	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-3.3031915323057763	[83]	[9]	-9	hSpCas9	negative selection	11028385
52517169	52517192	12	+	28162770	P31FUJ	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.05036984699049124	[165]	[201]	0	hSpCas9	negative selection	11028386
52519808	52519831	12	-	28162770	P31FUJ	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.017521149669861208	[189]	[225]	0	hSpCas9	negative selection	11028387
52517207	52517230	12	-	28162770	P31FUJ	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-0.10727132233051972	[142]	[155]	-1	hSpCas9	negative selection	11028388
52516692	52516715	12	-	28162770	P31FUJ	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-1.0967406548383505	[90]	[49]	-6	hSpCas9	negative selection	11028389
52520219	52520242	12	+	28162770	P31FUJ	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-1.7802899997168717	[75]	[25]	-8	hSpCas9	negative selection	11028390
52520204	52520227	12	+	28162770	P31FUJ	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.9557382386765267	[306]	[185]	-6	hSpCas9	negative selection	11028391
52520051	52520074	12	+	28162770	P31FUJ	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.8800459552558745	[337]	[730]	8	hSpCas9	negative selection	11028392
52519920	52519943	12	-	28162770	P31FUJ	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.30776617694832403	[186]	[271]	3	hSpCas9	negative selection	11028393
52519013	52519036	12	-	28162770	P31FUJ	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	1.9787019007793332	[18]	[87]	9	hSpCas9	negative selection	11028394
52519888	52519911	12	+	28162770	OCIAML5	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.07070685733933724	[31]	[54]	0	hSpCas9	negative selection	11197751
52517169	52517192	12	+	28162770	OCIAML5	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	-0.9998201913076892	[112]	[101]	-6	hSpCas9	negative selection	11197752
52519808	52519831	12	-	28162770	OCIAML5	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	1.5534481542963403	[56]	[301]	9	hSpCas9	negative selection	11197753
52517207	52517230	12	-	28162770	OCIAML5	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-0.5598858193706866	[97]	[119]	-4	hSpCas9	negative selection	11197754
52516692	52516715	12	-	28162770	OCIAML5	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	0.5781733350585172	[58]	[158]	5	hSpCas9	negative selection	11197755
52520219	52520242	12	+	28162770	OCIAML5	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-2.881813914258049	[48]	[11]	-8	hSpCas9	negative selection	11197756
52520204	52520227	12	+	28162770	OCIAML5	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-2.7477299110492615	[159]	[42]	-8	hSpCas9	negative selection	11197757
52520051	52520074	12	+	28162770	OCIAML5	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.9427723998017804	[214]	[745]	7	hSpCas9	negative selection	11197758
52519920	52519943	12	-	28162770	OCIAML5	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.995930335690953	[44]	[161]	8	hSpCas9	negative selection	11197759
52519013	52519036	12	-	28162770	OCIAML5	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-1.1321744900567325	[16]	[13]	-6	hSpCas9	negative selection	11197760
52519888	52519911	12	+	28162770	EOL1	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.7535241335421032	[159]	[49]	-5	hSpCas9	negative selection	11367117
52517169	52517192	12	+	28162770	EOL1	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.4033108684597655	[154]	[107]	3	hSpCas9	negative selection	11367118
52519808	52519831	12	-	28162770	EOL1	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	-0.24311772268965265	[318]	[141]	-2	hSpCas9	negative selection	11367119
52517207	52517230	12	-	28162770	EOL1	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.052008680752793135	[248]	[135]	0	hSpCas9	negative selection	11367120
52516692	52516715	12	-	28162770	EOL1	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	0.30745264990856946	[226]	[147]	3	hSpCas9	negative selection	11367121
52520219	52520242	12	+	28162770	EOL1	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.2414621798683947	[183]	[81]	-2	hSpCas9	negative selection	11367122
52520204	52520227	12	+	28162770	EOL1	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-2.348470722835881	[289]	[29]	-8	hSpCas9	negative selection	11367123
52520051	52520074	12	+	28162770	EOL1	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	-0.25831628557927583	[335]	[147]	-2	hSpCas9	negative selection	11367124
52519920	52519943	12	-	28162770	EOL1	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.3301865728471286	[153]	[101]	3	hSpCas9	negative selection	11367125
52519013	52519036	12	-	28162770	EOL1	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-0.9379487046795303	[39]	[10]	-6	hSpCas9	negative selection	11367126
52519888	52519911	12	+	28162770	MOLM13	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-1.3216908387850494	[120]	[34]	-6	hSpCas9	negative selection	11536483
52517169	52517192	12	+	28162770	MOLM13	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	-1.0939895060635358	[185]	[62]	-5	hSpCas9	negative selection	11536484
52519808	52519831	12	-	28162770	MOLM13	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	-0.05271387338019917	[273]	[190]	0	hSpCas9	negative selection	11536485
52517207	52517230	12	-	28162770	MOLM13	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-0.643141930844165	[269]	[124]	-4	hSpCas9	negative selection	11536486
52516692	52516715	12	-	28162770	MOLM13	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	0.3264169555916983	[181]	[164]	2	hSpCas9	negative selection	11536487
52520219	52520242	12	+	28162770	MOLM13	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-1.4004666126449503	[156]	[42]	-6	hSpCas9	negative selection	11536488
52520204	52520227	12	+	28162770	MOLM13	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.9672493237907742	[264]	[48]	-7	hSpCas9	negative selection	11536489
52520051	52520074	12	+	28162770	MOLM13	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.7038747475050063	[331]	[390]	5	hSpCas9	negative selection	11536490
52519920	52519943	12	-	28162770	MOLM13	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.178382764349594	[153]	[125]	1	hSpCas9	negative selection	11536491
52519013	52519036	12	-	28162770	MOLM13	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-2.6475878358753566	[25]	[2]	-8	hSpCas9	negative selection	11536492
52519888	52519911	12	+	28162770	HEL	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.8235791722221804	[104]	[37]	-5	hSpCas9	negative selection	11705849
52517169	52517192	12	+	28162770	HEL	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.9188632372745945	[127]	[154]	7	hSpCas9	negative selection	11705850
52519808	52519831	12	-	28162770	HEL	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	-1.0763603413723355	[213]	[64]	-6	hSpCas9	negative selection	11705851
52517207	52517230	12	-	28162770	HEL	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	0.9555810981292405	[222]	[276]	8	hSpCas9	negative selection	11705852
52516692	52516715	12	-	28162770	HEL	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-0.32119191329212127	[157]	[80]	-2	hSpCas9	negative selection	11705853
52520219	52520242	12	+	28162770	HEL	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.8447071628065369	[142]	[50]	-5	hSpCas9	negative selection	11705854
52520204	52520227	12	+	28162770	HEL	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.6988180696359381	[184]	[72]	-4	hSpCas9	negative selection	11705855
52520051	52520074	12	+	28162770	HEL	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.6035682347196794	[335]	[326]	5	hSpCas9	negative selection	11705856
52519920	52519943	12	-	28162770	HEL	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.1573120048301152	[111]	[79]	1	hSpCas9	negative selection	11705857
52519013	52519036	12	-	28162770	HEL	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	1.0952510366978636	[18]	[25]	8	hSpCas9	negative selection	11705858
52519888	52519911	12	+	28162770	MV411	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	-0.6005593557721747	[80]	[44]	-4	hSpCas9	negative selection	11875215
52517169	52517192	12	+	28162770	MV411	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	-0.9060369298789428	[108]	[48]	-6	hSpCas9	negative selection	11875216
52519808	52519831	12	-	28162770	MV411	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.6038290552383593	[181]	[232]	5	hSpCas9	negative selection	11875217
52517207	52517230	12	-	28162770	MV411	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-0.4124870076196031	[157]	[99]	-3	hSpCas9	negative selection	11875218
52516692	52516715	12	-	28162770	MV411	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-0.1169738754261006	[111]	[86]	-1	hSpCas9	negative selection	11875219
52520219	52520242	12	+	28162770	MV411	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.952861099703056	[107]	[46]	-6	hSpCas9	negative selection	11875220
52520204	52520227	12	+	28162770	MV411	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-1.1249803145582802	[188]	[72]	-6	hSpCas9	negative selection	11875221
52520051	52520074	12	+	28162770	MV411	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.36194943190648105	[229]	[248]	3	hSpCas9	negative selection	11875222
52519920	52519943	12	-	28162770	MV411	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.11208569788788902	[66]	[60]	1	hSpCas9	negative selection	11875223
52519013	52519036	12	-	28162770	MV411	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	0.9148622116959046	[16]	[26]	7	hSpCas9	negative selection	11875224
52519888	52519911	12	+	28162770	MONOMAC1	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	0.354605580461576	[72]	[106]	3	hSpCas9	negative selection	12044581
52517169	52517192	12	+	28162770	MONOMAC1	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	1.2352786436511258	[82]	[223]	9	hSpCas9	negative selection	12044582
52519808	52519831	12	-	28162770	MONOMAC1	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.662785494892186	[107]	[195]	6	hSpCas9	negative selection	12044583
52517207	52517230	12	-	28162770	MONOMAC1	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-0.7275515637583333	[116]	[80]	-5	hSpCas9	negative selection	12044584
52516692	52516715	12	-	28162770	MONOMAC1	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	-0.25593053611312233	[74]	[71]	-2	hSpCas9	negative selection	12044585
52520219	52520242	12	+	28162770	MONOMAC1	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-0.37391460914363306	[77]	[68]	-3	hSpCas9	negative selection	12044586
52520204	52520227	12	+	28162770	MONOMAC1	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.8644615079726828	[107]	[67]	-6	hSpCas9	negative selection	12044587
52520051	52520074	12	+	28162770	MONOMAC1	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.33901605318065614	[139]	[202]	3	hSpCas9	negative selection	12044588
52519920	52519943	12	-	28162770	MONOMAC1	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.6424984807472003	[56]	[101]	6	hSpCas9	negative selection	12044589
52519013	52519036	12	-	28162770	MONOMAC1	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-0.8751087521721912	[7]	[4]	-6	hSpCas9	negative selection	12044590
52519888	52519911	12	+	28162770	OCIAML2	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	0.3194471053836072	[11]	[82]	3	hSpCas9	negative selection	12213947
52517169	52517192	12	+	28162770	OCIAML2	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	0.33672509681544305	[17]	[125]	3	hSpCas9	negative selection	12213948
52519808	52519831	12	-	28162770	OCIAML2	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.16034507323583116	[35]	[222]	1	hSpCas9	negative selection	12213949
52517207	52517230	12	-	28162770	OCIAML2	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-0.6139940004133386	[36]	[133]	-4	hSpCas9	negative selection	12213950
52516692	52516715	12	-	28162770	OCIAML2	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	0.2537357321444114	[22]	[151]	2	hSpCas9	negative selection	12213951
52520219	52520242	12	+	28162770	OCIAML2	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-1.9300614438794585	[10]	[15]	-8	hSpCas9	negative selection	12213952
52520204	52520227	12	+	28162770	OCIAML2	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.6570429494730425	[32]	[115]	-5	hSpCas9	negative selection	12213953
52520051	52520074	12	+	28162770	OCIAML2	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	0.4191872570074159	[50]	[377]	4	hSpCas9	negative selection	12213954
52519920	52519943	12	-	28162770	OCIAML2	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	0.8283371212018901	[18]	[186]	7	hSpCas9	negative selection	12213955
52519013	52519036	12	-	28162770	OCIAML2	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-2.148701730354799	[3]	[4]	-8	hSpCas9	negative selection	12213956
52519888	52519911	12	+	28162770	OCIAML3	viability	GAGGGCAGACAGGAAAGCCAGGG	KRT5	ENSG00000186081	0.23196295990078797	[10]	[38]	2	hSpCas9	negative selection	12383313
52517169	52517192	12	+	28162770	OCIAML3	viability	TCTCATGCTTGGTGTTGCGGAGG	KRT5	ENSG00000186081	-0.30182688883085285	[48]	[119]	-2	hSpCas9	negative selection	12383314
52519808	52519831	12	-	28162770	OCIAML3	viability	AAATCGACCCCAGCATCCAGAGG	KRT5	ENSG00000186081	0.451316350185327	[46]	[193]	4	hSpCas9	negative selection	12383315
52517207	52517230	12	-	28162770	OCIAML3	viability	GAGGAGCTGCAGCAGACAGCTGG	KRT5	ENSG00000186081	-1.485073268770999	[50]	[54]	-7	hSpCas9	negative selection	12383316
52516692	52516715	12	-	28162770	OCIAML3	viability	GGAGCTCATGAACACCAAGCTGG	KRT5	ENSG00000186081	0.5936193628516081	[17]	[81]	5	hSpCas9	negative selection	12383317
52520219	52520242	12	+	28162770	OCIAML3	viability	AGACGGGGTGATGGCAGAGGCGG	KRT5	ENSG00000186081	-1.1030212878120207	[36]	[51]	-7	hSpCas9	negative selection	12383318
52520204	52520227	12	+	28162770	OCIAML3	viability	GCTGGTGCGGGAGACAGACGGGG	KRT5	ENSG00000186081	-0.31547214095018145	[53]	[130]	-2	hSpCas9	negative selection	12383319
52520051	52520074	12	+	28162770	OCIAML3	viability	GCTGCCACCACTAGTGCTGATGG	KRT5	ENSG00000186081	1.0262617291329459	[73]	[454]	8	hSpCas9	negative selection	12383320
52519920	52519943	12	-	28162770	OCIAML3	viability	GGCGGAGCTGGCTTTGGAGGTGG	KRT5	ENSG00000186081	-0.1504009888485487	[24]	[67]	-1	hSpCas9	negative selection	12383321
52519013	52519036	12	-	28162770	OCIAML3	viability	GAGGCAGCTGGACAGCATCGTGG	KRT5	ENSG00000186081	-1.746010733769213	[9]	[8]	-8	hSpCas9	negative selection	12383322