Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3853
• Symbol:KRT6A
• Description:keratin 6A

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT6A

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52491586	52491609	12	-	26472758	Jiyoye	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	1.3603811700269322	[140]	[272]	7	hSpCas9	negative selection	86598
52487894	52487917	12	+	26472758	Jiyoye	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.8652257697448101	[189]	[260]	6	hSpCas9	negative selection	86599
52491538	52491561	12	-	26472758	Jiyoye	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-0.6599388143526637	[87]	[41]	-5	hSpCas9	negative selection	86600
52491692	52491715	12	-	26472758	Jiyoye	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.7918392317411986	[71]	[93]	5	hSpCas9	negative selection	86601
52491679	52491702	12	-	26472758	Jiyoye	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.8065312585524473	[184]	[243]	5	hSpCas9	negative selection	86602
52492702	52492725	12	-	26472758	Jiyoye	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	-1.8072682867150838	[180]	[38]	-8	hSpCas9	negative selection	86603
52491555	52491578	12	-	26472758	Jiyoye	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.6955102824686907	[130]	[60]	-5	hSpCas9	negative selection	86604
52488522	52488545	12	+	26472758	Jiyoye	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	-0.5928246184941265	[183]	[91]	-4	hSpCas9	negative selection	86605
52488335	52488358	12	-	26472758	Jiyoye	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.6229040725613108	[92]	[107]	4	hSpCas9	negative selection	86606
52491565	52491588	12	-	26472758	Jiyoye	viability	GGAACGGGGCCGCCTGGACTCAG	KRT6A	ENSG00000205420	0.9921378822270295	[27]	[41]	6	hSpCas9	negative selection	86620
52491586	52491609	12	-	26472758	KBM7	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	-0.3623256686753045	[896,758]	[400,212]	-3	hSpCas9	negative selection	277716
52487894	52487917	12	+	26472758	KBM7	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.1015670390329948	[1375,1797]	[807,821]	1	hSpCas9	negative selection	277717
52491538	52491561	12	-	26472758	KBM7	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	0.6539251482264166	[238,181]	[81,218]	7	hSpCas9	negative selection	277718
52491692	52491715	12	-	26472758	KBM7	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.15810676391936782	[640,398]	[396,151]	1	hSpCas9	negative selection	277719
52491679	52491702	12	-	26472758	KBM7	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.5724829020313275	[912,664]	[658,443]	6	hSpCas9	negative selection	277720
52492702	52492725	12	-	26472758	KBM7	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.5255232925658062	[169,152]	[113,104]	6	hSpCas9	negative selection	277721
52491555	52491578	12	-	26472758	KBM7	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.894448920401417	[370,351]	[209,411]	8	hSpCas9	negative selection	277722
52488522	52488545	12	+	26472758	KBM7	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.10592427858994602	[294,203]	[180,73]	1	hSpCas9	negative selection	277723
52488335	52488358	12	-	26472758	KBM7	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.3343266695005514	[657,620]	[335,418]	3	hSpCas9	negative selection	277724
52491565	52491588	12	-	26472758	KBM7	viability	GGAACGGGGCCGCCTGGACTCAG	KRT6A	ENSG00000205420	0.7687408847353805	[307,189]	[202,188]	8	hSpCas9	negative selection	277738
52491586	52491609	12	-	26472758	Raji	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.08288897345285107	[296]	[72]	0	hSpCas9	negative selection	468834
52487894	52487917	12	+	26472758	Raji	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.1235032007368766	[533]	[134]	1	hSpCas9	negative selection	468835
52491538	52491561	12	-	26472758	Raji	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-1.140543978069986	[94]	[9]	-7	hSpCas9	negative selection	468836
52491692	52491715	12	-	26472758	Raji	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	1.1650990332298867	[195]	[101]	8	hSpCas9	negative selection	468837
52491679	52491702	12	-	26472758	Raji	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.8478636137160425	[327]	[136]	7	hSpCas9	negative selection	468838
52492702	52492725	12	-	26472758	Raji	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.40111473843030965	[123]	[37]	4	hSpCas9	negative selection	468839
52491555	52491578	12	-	26472758	Raji	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.29641735976361644	[199]	[56]	3	hSpCas9	negative selection	468840
52488522	52488545	12	+	26472758	Raji	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.8779016892508321	[135]	[57]	7	hSpCas9	negative selection	468841
52488335	52488358	12	-	26472758	Raji	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.5130223366501938	[461]	[152]	5	hSpCas9	negative selection	468842
52491565	52491588	12	-	26472758	Raji	viability	GGAACGGGGCCGCCTGGACTCAG	KRT6A	ENSG00000205420	1.4149563372838918	[201]	[124]	9	hSpCas9	negative selection	468856
52491586	52491609	12	-	26472758	K562	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	-0.24898983516526935	[579]	[411]	-2	hSpCas9	negative selection	659952
52487894	52487917	12	+	26472758	K562	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.6077461670564159	[1057]	[1360]	5	hSpCas9	negative selection	659953
52491538	52491561	12	-	26472758	K562	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	1.4370638056088425	[153]	[351]	9	hSpCas9	negative selection	659954
52491692	52491715	12	-	26472758	K562	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.24125838677311878	[456]	[455]	1	hSpCas9	negative selection	659955
52491679	52491702	12	-	26472758	K562	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.37900476803408734	[674]	[740]	3	hSpCas9	negative selection	659956
52492702	52492725	12	-	26472758	K562	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	-0.06899786736539804	[337]	[271]	0	hSpCas9	negative selection	659957
52491555	52491578	12	-	26472758	K562	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	1.4494475300646752	[202]	[467]	9	hSpCas9	negative selection	659958
52488522	52488545	12	+	26472758	K562	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.6576696074712765	[201]	[268]	5	hSpCas9	negative selection	659959
52488335	52488358	12	-	26472758	K562	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.9137915407844929	[602]	[958]	7	hSpCas9	negative selection	659960
52491565	52491588	12	-	26472758	K562	viability	GGAACGGGGCCGCCTGGACTCAG	KRT6A	ENSG00000205420	-0.017322361145826415	[222]	[185]	0	hSpCas9	negative selection	659974
52492715	52492738	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.7392485541066234	[3,3]	[1,1]	-8	hSpCas9	positive selection	2998231
52492714	52492737	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AATCGATCCCACCATCCAGCGGG	KRT6A	ENSG00000205420	0.3185623295247342	[3,3]	[3,4]	6	hSpCas9	positive selection	2998232
52491692	52491715	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.4093306890816179	[2,2]	[2,3]	8	hSpCas9	positive selection	2998233
52493081	52493104	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGACGCTGCTGAAGCCAGAGCGG	KRT6A	ENSG00000205420	-0.6959887155116309	[0,1]	[0,0]	-8	hSpCas9	positive selection	2998234
52492715	52492738	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.7030717594872326	[3,3]	[3,4]	9	hSpCas9	positive selection	3066089
52492714	52492737	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AATCGATCCCACCATCCAGCGGG	KRT6A	ENSG00000205420	-0.4342686518548051	[3,3]	[3,0]	-6	hSpCas9	positive selection	3066090
52491692	52491715	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.14962240404285784	[2,2]	[2,0]	-2	hSpCas9	positive selection	3066091
52493081	52493104	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGACGCTGCTGAAGCCAGAGCGG	KRT6A	ENSG00000205420	0.36669681316117764	[0,0]	[1,0]	6	hSpCas9	positive selection	3066092
52491555	52491578		-	24336571	A375	resistance to PLX after 7 days	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.013611021014540703	[8,7]	[7,8]	0	hSpCas9	positive selection	3123804
52493063	52493086		-	24336571	A375	resistance to PLX after 7 days	GCGTCTCCGTGTCCCGCTCCAGG	KRT6A	ENSG00000205420	-0.3668101544319093	[19,13]	[12,12]	-9	hSpCas9	positive selection	3123805
52491724	52491747		-	24336571	A375	resistance to PLX after 7 days	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	-0.19354847231898353	[8,6]	[7,5]	-6	hSpCas9	positive selection	3123806
52492726	52492749		+	24336571	A375	resistance to PLX after 7 days	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.023066638841718	[25,24]	[24,25]	0	hSpCas9	positive selection	3123807
52491555	52491578		-	24336571	A375	resistance to PLX after 14 days	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.4380911079855683	[11,7]	[2,2]	-5	hSpCas9	positive selection	3181597
52493063	52493086		-	24336571	A375	resistance to PLX after 14 days	GCGTCTCCGTGTCCCGCTCCAGG	KRT6A	ENSG00000205420	-0.8176072585653212	[17,14]	[3,3]	-8	hSpCas9	positive selection	3181598
52491724	52491747		-	24336571	A375	resistance to PLX after 14 days	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.1452356262895902	[5,5]	[2,1]	1	hSpCas9	positive selection	3181599
52492726	52492749		+	24336571	A375	resistance to PLX after 14 days	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	-0.7011623092891588	[25,32]	[8,6]	-7	hSpCas9	positive selection	3181600
52491555	52491578		-	24336571	A375	viability after 7 days	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.11928838676086256	[9]	[8,7]	-2	hSpCas9	negative selection	3239390
52493063	52493086		-	24336571	A375	viability after 7 days	GCGTCTCCGTGTCCCGCTCCAGG	KRT6A	ENSG00000205420	0.3135912750259811	[13]	[19,13]	5	hSpCas9	negative selection	3239391
52491724	52491747		-	24336571	A375	viability after 7 days	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	1.0434647743026038	[3]	[8,6]	9	hSpCas9	negative selection	3239392
52492726	52492749		+	24336571	A375	viability after 7 days	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.6887880718988787	[16]	[25,24]	8	hSpCas9	negative selection	3239393
52491555	52491578		-	24336571	A375	viability after 14 days	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.1337671245401591	[9]	[11,7]	1	hSpCas9	negative selection	3297183
52493063	52493086		-	24336571	A375	viability after 14 days	GCGTCTCCGTGTCCCGCTCCAGG	KRT6A	ENSG00000205420	0.2684260168636699	[13]	[17,14]	3	hSpCas9	negative selection	3297184
52491724	52491747		-	24336571	A375	viability after 14 days	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5910324246759298	[3]	[5,5]	7	hSpCas9	negative selection	3297185
52492726	52492749		+	24336571	A375	viability after 14 days	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.9293900010856191	[16]	[25,32]	9	hSpCas9	negative selection	3297186
52492715	52492738	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.2425196756373702	[180,180]	[0,0]	-1	hSpCas9	positive selection	3376330
52491555	52491578	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.07741712143090065	[144,144]	[0,0]	0	hSpCas9	positive selection	3376331
52492715	52492738	12	-	26780180	HT29	viability (Avana library 4 designs)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	2.08582105809765	[]	[]	7	hSpCas9	negative selection	3435685
52492714	52492737	12	-	26780180	HT29	viability (Avana library 4 designs)	AATCGATCCCACCATCCAGCGGG	KRT6A	ENSG00000205420	1.85792660764421	[]	[]	7	hSpCas9	negative selection	3435686
52491692	52491715	12	-	26780180	HT29	viability (Avana library 4 designs)	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	1.3053319623844	[]	[]	5	hSpCas9	negative selection	3435687
52493080	52493103	12	+	26780180	HT29	viability (Avana library 4 designs)	AGACGCTGCTGAAGCCAGAGCGG	KRT6A	ENSG00000205420	0.176821224842396	[]	[]	0	hSpCas9	negative selection	3435688
52492715	52492738	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.736725095438676	[]	[]	-1	hSpCas9	negative selection	3523373
52491692	52491715	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.520033766496162	[]	[]	0	hSpCas9	negative selection	3523374
52493080	52493103	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGACGCTGCTGAAGCCAGAGCGG	KRT6A	ENSG00000205420	-2.95646965351291	[]	[]	-4	hSpCas9	negative selection	3523375
52492714	52492737	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AATCGATCCCACCATCCAGCGGG	KRT6A	ENSG00000205420	-8.40495353624221	[]	[]	-7	hSpCas9	negative selection	3523376
52491556	52491579	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCTGAGCTCTGAGTCCAGGCGG	KRT6A	ENSG00000205420	4.33311855564612	[]	[]	7	hSpCas9	negative selection	3523377
52491523	52491546	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	TGTTCTTGAAGTCCTCCACCAGG	KRT6A	ENSG00000205420	2.89508624250543	[]	[]	4	hSpCas9	negative selection	3523378
52492715	52492738	12	-	26780180	A375	viability (Avana lentiGuide)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	6.65316676159682	[]	[]	5	hSpCas9	negative selection	3632032
52491692	52491715	12	-	26780180	A375	viability (Avana lentiGuide)	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.0727353530041732	[]	[]	0	hSpCas9	negative selection	3632033
52493080	52493103	12	+	26780180	A375	viability (Avana lentiGuide)	AGACGCTGCTGAAGCCAGAGCGG	KRT6A	ENSG00000205420	10.1634024710701	[]	[]	7	hSpCas9	negative selection	3632034
52492714	52492737	12	-	26780180	A375	viability (Avana lentiGuide)	AATCGATCCCACCATCCAGCGGG	KRT6A	ENSG00000205420	6.56252234656423	[]	[]	5	hSpCas9	negative selection	3632035
52491556	52491579	12	+	26780180	A375	viability (Avana lentiGuide)	CTCTGAGCTCTGAGTCCAGGCGG	KRT6A	ENSG00000205420	-7.23732561477574	[]	[]	-9	hSpCas9	negative selection	3632036
52491523	52491546	12	+	26780180	A375	viability (Avana lentiGuide)	TGTTCTTGAAGTCCTCCACCAGG	KRT6A	ENSG00000205420	3.413435180205	[]	[]	3	hSpCas9	negative selection	3632037
52492715	52492738	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.030444840511406536	[4]	[5,3]	0	hSpCas9	positive selection	3740691
52491692	52491715	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.8283507605207457	[4]	[4,0]	-8	hSpCas9	positive selection	3740692
52493080	52493103	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACGCTGCTGAAGCCAGAGCGG	KRT6A	ENSG00000205420	-0.8674763457066708	[1]	[0,0]	-8	hSpCas9	positive selection	3740693
52492714	52492737	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AATCGATCCCACCATCCAGCGGG	KRT6A	ENSG00000205420	-0.5410937540105732	[4]	[2,3]	-7	hSpCas9	positive selection	3740694
52491556	52491579	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCTGAGCTCTGAGTCCAGGCGG	KRT6A	ENSG00000205420	0.49042408620617944	[4]	[6,6]	9	hSpCas9	positive selection	3740695
52491523	52491546	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGTTCTTGAAGTCCTCCACCAGG	KRT6A	ENSG00000205420	0.06875385737129311	[5]	[4,5]	1	hSpCas9	positive selection	3740696
52492715	52492738	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.04715722009644786	[5]	[5,3]	1	hSpCas9	positive selection	3849298
52491692	52491715	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.16251822286155498	[4]	[2,4]	-2	hSpCas9	positive selection	3849299
52493080	52493103	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACGCTGCTGAAGCCAGAGCGG	KRT6A	ENSG00000205420	-1.1203499763798617	[1]	[0,0]	-8	hSpCas9	positive selection	3849300
52492714	52492737	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AATCGATCCCACCATCCAGCGGG	KRT6A	ENSG00000205420	0.06082436141099184	[5]	[3,5]	1	hSpCas9	positive selection	3849301
52491556	52491579	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCTGAGCTCTGAGTCCAGGCGG	KRT6A	ENSG00000205420	0.38423856455384764	[5]	[5,6]	9	hSpCas9	positive selection	3849302
52491523	52491546	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGTTCTTGAAGTCCTCCACCAGG	KRT6A	ENSG00000205420	0.11608287335486284	[6]	[5,6]	2	hSpCas9	positive selection	3849303
52492715	52492738	12	-	26780180	A375	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	1.39362616640424	[]	[]	7	hSpCas9	negative selection	3955382
52491588	52491611	12	-	26780180	A375	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.76921821406821	[]	[]	3	hSpCas9	negative selection	3955383
52491555	52491578	12	-	26780180	A375	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	1.0101594707793	[]	[]	5	hSpCas9	negative selection	3955384
52491724	52491747	12	-	26780180	A375	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.576983782251058	[]	[]	1	hSpCas9	negative selection	3955385
52491111	52491134	12	-	26780180	A375	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	1.92129410222895	[]	[]	9	hSpCas9	negative selection	3955386
52492726	52492749	12	+	26780180	A375	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.906529345132559	[]	[]	4	hSpCas9	negative selection	3955387
52492715	52492738	12	-	26780180	HT29	viability (GeCKOv2 library)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.633817190720953	[]	[]	2	hSpCas9	negative selection	4063348
52491588	52491611	12	-	26780180	HT29	viability (GeCKOv2 library)	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.133756486753027	[]	[]	0	hSpCas9	negative selection	4063349
52491555	52491578	12	-	26780180	HT29	viability (GeCKOv2 library)	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.770124339292272	[]	[]	3	hSpCas9	negative selection	4063350
52491724	52491747	12	-	26780180	HT29	viability (GeCKOv2 library)	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.781430307094627	[]	[]	3	hSpCas9	negative selection	4063351
52491111	52491134	12	-	26780180	HT29	viability (GeCKOv2 library)	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	0.528684663326692	[]	[]	1	hSpCas9	negative selection	4063352
52492726	52492749	12	+	26780180	HT29	viability (GeCKOv2 library)	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	-0.0464567563229517	[]	[]	-1	hSpCas9	negative selection	4063353
52491555	52491578	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.18414260158851103	[3]	[1,1]	-4	hSpCas9	positive selection	4147774
52493063	52493086	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGTCTCCGTGTCCCGCTCCAGG	KRT6A	ENSG00000205420	-0.34511615950099983	[3]	[1,1]	-7	hSpCas9	positive selection	4147775
52491724	52491747	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	-0.2968114711959008	[3]	[2,1]	-6	hSpCas9	positive selection	4147776
52492726	52492749	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	-0.011657652188755335	[4]	[2,2]	0	hSpCas9	positive selection	4147777
52491555	52491578	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.034090588729496406	[3]	[3,0,1,0]	0	hSpCas9	positive selection	4211796
52493063	52493086	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGTCTCCGTGTCCCGCTCCAGG	KRT6A	ENSG00000205420	1.0410587658483568	[3]	[1,3,0,3]	7	hSpCas9	positive selection	4211797
52491724	52491747	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.6619052887201705	[3]	[0,0,0,4]	4	hSpCas9	positive selection	4211798
52492726	52492749	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.07188018358657569	[4]	[3,2,0,0]	0	hSpCas9	positive selection	4211799
52491724	52491747	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.24194846348494792	[3]	[3,1]	5	hSpCas9	positive selection	4279188
52491588	52491611	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.169575003759656	[4]	[3,3]	3	hSpCas9	positive selection	4279189
52492726	52492749	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.4436955268973061	[3]	[4,3]	8	hSpCas9	positive selection	4279190
52492715	52492738	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.21291453364728113	[3]	[2,2]	-4	hSpCas9	positive selection	4343443
52491555	52491578	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.04518812266509756	[2]	[3,0]	-1	hSpCas9	positive selection	4343445
52491111	52491134	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.40339239200602806	[3]	[2,0]	-7	hSpCas9	positive selection	4343451
52491547	52491569	12	-	27760321	OCIAML3	viability	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	0.39085419259584775	[12,4]	[14,0]	5	hSpCas9	negative selection	4413189
52491579	52491601	12	-	27760321	OCIAML3	viability	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	-0.5157112416338774	[485,424]	[255,238]	-5	hSpCas9	negative selection	4413190
52492715	52492737	12	-	27760321	OCIAML3	viability	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.1946311177522285	[583,504]	[384,352]	-2	hSpCas9	negative selection	4413191
52491547	52491569	12	-	27760321	OCIAML2	viability	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	-0.03215234081268559	[12,4]	[2,11]	0	hSpCas9	negative selection	4496652
52491579	52491601	12	-	27760321	OCIAML2	viability	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	0.09557988669642883	[485,424]	[372,418]	1	hSpCas9	negative selection	4496653
52492715	52492737	12	-	27760321	OCIAML2	viability	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-1.1071194523739818	[583,504]	[171,245]	-8	hSpCas9	negative selection	4496654
52491547	52491569	12	-	27760321	MV411	viability	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	-2.521537241358856	[12,4]	[0,0]	-9	hSpCas9	negative selection	4580115
52491579	52491601	12	-	27760321	MV411	viability	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	-0.3926917753449566	[485,424]	[289,135]	-3	hSpCas9	negative selection	4580116
52492715	52492737	12	-	27760321	MV411	viability	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	1.350348778470556	[583,504]	[1292,343]	8	hSpCas9	negative selection	4580117
52491547	52491569	12	-	27760321	HL60	viability	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	-2.8294074031529926	[12,4]	[0,0]	-9	hSpCas9	negative selection	4663578
52491579	52491601	12	-	27760321	HL60	viability	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	-0.2848259181155808	[485,424]	[312,295]	-3	hSpCas9	negative selection	4663579
52492715	52492737	12	-	27760321	HL60	viability	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-1.0256295197534924	[583,504]	[230,203]	-7	hSpCas9	negative selection	4663580
52491547	52491569	12	-	27760321	HT1080	viability	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	-0.8443172389209588	[4,3]	[0,0]	-4	hSpCas9	negative selection	4747041
52491579	52491601	12	-	27760321	HT1080	viability	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	-0.5759645554388241	[424,331]	[114,85]	-3	hSpCas9	negative selection	4747042
52492715	52492737	12	-	27760321	HT1080	viability	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.9560765708296839	[504,393]	[66,119]	-4	hSpCas9	negative selection	4747043
52491547	52491569	12	-	27760321	HT29	viability after 7 days	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	-1.775192247223476	[4,3]	[0,2,0]	-9	hSpCas9	negative selection	4830504
52491579	52491601	12	-	27760321	HT29	viability after 7 days	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	0.11191786418531834	[424,331]	[593,570,424]	1	hSpCas9	negative selection	4830505
52492715	52492737	12	-	27760321	HT29	viability after 7 days	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.36091024460702725	[504,393]	[885,586,771]	5	hSpCas9	negative selection	4830506
52491547	52491569	12	-	27760321	HT29	viability after 25 days	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	2.137928037281285	[4,3]	[35,0,30]	9	hSpCas9	negative selection	4913967
52491579	52491601	12	-	27760321	HT29	viability after 25 days	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	0.21789804323789108	[424,331]	[646,370,478]	2	hSpCas9	negative selection	4913968
52492715	52492737	12	-	27760321	HT29	viability after 25 days	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.21128546657055325	[504,393]	[375,584,863]	2	hSpCas9	negative selection	4913969
52491547	52491569	12	-	27760321	HT29	viability after 22 days	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	0.10296217075338276	[4,3]	[0,0,14]	1	hSpCas9	negative selection	4997430
52491579	52491601	12	-	27760321	HT29	viability after 22 days	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	0.22529815757961297	[424,331]	[520,540,471]	2	hSpCas9	negative selection	4997431
52492715	52492737	12	-	27760321	HT29	viability after 22 days	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.009350774613342439	[504,393]	[272,546,757]	0	hSpCas9	negative selection	4997432
52491547	52491569	12	-	27760321	HT29	viability after 19 days	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	2.529622506414375	[4,3]	[4,6,72]	9	hSpCas9	negative selection	5080893
52491579	52491601	12	-	27760321	HT29	viability after 19 days	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	0.3967249886384784	[424,331]	[717,412,592]	4	hSpCas9	negative selection	5080894
52492715	52492737	12	-	27760321	HT29	viability after 19 days	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.1763658588294102	[504,393]	[717,679,366]	1	hSpCas9	negative selection	5080895
52491547	52491569	12	-	27760321	HT29	viability after 16 days	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	0.8669067495048983	[4,3]	[0,1,23]	8	hSpCas9	negative selection	5164356
52491579	52491601	12	-	27760321	HT29	viability after 16 days	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	-0.12675074911717632	[424,331]	[519,350,305]	-1	hSpCas9	negative selection	5164357
52492715	52492737	12	-	27760321	HT29	viability after 16 days	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.06913699931677292	[504,393]	[272,473,812]	0	hSpCas9	negative selection	5164358
52491547	52491569	12	-	27760321	HT29	viability after 13 days	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	1.0800045966970506	[4,3]	[0,0,29]	9	hSpCas9	negative selection	5247819
52491579	52491601	12	-	27760321	HT29	viability after 13 days	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	-0.09703535930866747	[424,331]	[412,465,355]	-1	hSpCas9	negative selection	5247820
52492715	52492737	12	-	27760321	HT29	viability after 13 days	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.3035402508256393	[504,393]	[730,753,456]	4	hSpCas9	negative selection	5247821
52491547	52491569	12	-	27760321	HT29	viability after 10 days	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	0.38588549091749247	[4,3]	[18,0,1]	5	hSpCas9	negative selection	5331282
52491579	52491601	12	-	27760321	HT29	viability after 10 days	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	-0.21981522282727012	[424,331]	[518,507,197]	-3	hSpCas9	negative selection	5331283
52492715	52492737	12	-	27760321	HT29	viability after 10 days	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.35342308684553614	[504,393]	[349,423,540]	-4	hSpCas9	negative selection	5331284
52491547	52491569	12	-	27760321	MOLM13	viability	TCAGAGCTCAGAGGCATGCAGG	KRT6A	ENSG00000205420	2.7667120411612935	[12,4]	[0,60]	9	hSpCas9	negative selection	5414745
52491579	52491601	12	-	27760321	MOLM13	viability	ACAGCATTGTCGGGGAACGGGG	KRT6A	ENSG00000205420	1.154336204159604	[485,424]	[674,481]	7	hSpCas9	negative selection	5414746
52492715	52492737	12	-	27760321	MOLM13	viability	AATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.5951863388729026	[583,504]	[359,68]	-4	hSpCas9	negative selection	5414747
52493150	52493173	12	+	27661255	K562	viability	GCTGCTGTGGCTCCTGATGGTGG	KRT6A	ENSG00000205420	-0.0005949184157127974	[385,438]	[360,300]	0	dCas9-KRAB	negative selection	5489323
52493238	52493261	12	+	27661255	K562	viability	GAGGGAAGAGAAGCAGGACTAGG	KRT6A	ENSG00000205420	-0.06410458827097465	[597,608]	[555,379]	-2	dCas9-KRAB	negative selection	5489324
52493245	52493268	12	+	27661255	K562	viability	GAGAAGCAGGACTAGGAATCAGG	KRT6A	ENSG00000205420	0.23238859181652438	[504,757]	[637,545]	7	dCas9-KRAB	negative selection	5489325
52491541	52491564	12	-	27661255	K562	viability	GCTCAGAGGCATGCAGGACCTGG	KRT6A	ENSG00000205420	0.5468716338941273	[43,49]	[71,39]	9	dCas9-KRAB	negative selection	5489326
52491586	52491609	12	-	27661255	K562	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.16939319859968016	[335,359]	[342,285]	6	dCas9-KRAB	negative selection	5489327
52493031	52493054	12	-	27661255	K562	viability	GGCCTGGGTGGTGCATGTGGAGG	KRT6A	ENSG00000205420	0.11262809021642439	[517,621]	[501,480]	4	dCas9-KRAB	negative selection	5489328
52491724	52491747	12	-	27260156	BXPC3	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.4913811724082265	[487]	[676,658,859,672]	9	hSpCas9	negative selection	5551648
52491588	52491611	12	-	27260156	BXPC3	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.1744468344732255	[1110]	[883,951,1218,1085]	-4	hSpCas9	negative selection	5551649
52492726	52492749	12	+	27260156	BXPC3	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.5460003166075839	[574]	[809,746,807,1192]	9	hSpCas9	negative selection	5551650
52492715	52492738	12	-	27260156	BXPC3	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.31859722501367427	[810]	[824,535,643,704]	-6	hSpCas9	negative selection	5615903
52491555	52491578	12	-	27260156	BXPC3	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.14600959150027193	[410]	[430,469,451,560]	3	hSpCas9	negative selection	5615905
52491111	52491134	12	-	27260156	BXPC3	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.28307186410578733	[645]	[541,615,435,626]	-6	hSpCas9	negative selection	5615911
52491724	52491747	12	-	27260156	A673	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5238945169971674	[487]	[960,908,739,766]	9	hSpCas9	negative selection	5672899
52491588	52491611	12	-	27260156	A673	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.07112590592525825	[1110]	[1527,1255,1420,1416]	1	hSpCas9	negative selection	5672900
52492726	52492749	12	+	27260156	A673	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.4493539381505346	[574]	[1035,953,968,812]	8	hSpCas9	negative selection	5672901
52492715	52492738	12	-	27260156	A673	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.10144489072477791	[810]	[1023,910,875,826]	-3	hSpCas9	negative selection	5737154
52491555	52491578	12	-	27260156	A673	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.14947517510198569	[410]	[449,465,477,380]	-4	hSpCas9	negative selection	5737156
52491111	52491134	12	-	27260156	A673	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.13400455067971206	[645]	[659,829,667,656]	-3	hSpCas9	negative selection	5737162
52491724	52491747	12	-	27260156	A375	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.819129391637526	[487]	[992,1386,800,902]	9	hSpCas9	negative selection	5794150
52491588	52491611	12	-	27260156	A375	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.03961463643531005	[1110]	[1444,1334,1166,1125]	0	hSpCas9	negative selection	5794151
52492726	52492749	12	+	27260156	A375	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	1.0351801083790138	[574]	[1683,1233,1534,1066]	9	hSpCas9	negative selection	5794152
52492715	52492738	12	-	27260156	A375	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.8014876927797238	[810]	[446,537,730,463]	-7	hSpCas9	negative selection	5858405
52491555	52491578	12	-	27260156	A375	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.2315637335817697	[410]	[642,701,574,374]	3	hSpCas9	negative selection	5858407
52491111	52491134	12	-	27260156	A375	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.2519915688904384	[645]	[725,735,692,417]	-4	hSpCas9	negative selection	5858413
52491724	52491747	12	-	27260156	COLO741	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.555901123016484	[487]	[1112,830,826]	9	hSpCas9	negative selection	5915401
52491588	52491611	12	-	27260156	COLO741	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.03163213019909761	[1110]	[1532,1377,1272]	0	hSpCas9	negative selection	5915402
52492726	52492749	12	+	27260156	COLO741	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.6423095777510128	[574]	[1516,1010,954]	9	hSpCas9	negative selection	5915403
52492715	52492738	12	-	27260156	COLO741	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.009595426929868478	[810]	[1052,925,1102]	0	hSpCas9	negative selection	5979656
52491555	52491578	12	-	27260156	COLO741	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.11020817738150393	[410]	[445,548,461]	-2	hSpCas9	negative selection	5979658
52491111	52491134	12	-	27260156	COLO741	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.16439103291991636	[645]	[713,838,658]	-4	hSpCas9	negative selection	5979664
52491724	52491747	12	-	27260156	CAL120	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.84702371507496	[487]	[1472,1169,697]	9	hSpCas9	negative selection	6036652
52491588	52491611	12	-	27260156	CAL120	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.049377950806637205	[1110]	[2067,1153,1169]	0	hSpCas9	negative selection	6036653
52492726	52492749	12	+	27260156	CAL120	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.8897655146680802	[574]	[1141,1250,1551]	9	hSpCas9	negative selection	6036654
52492715	52492738	12	-	27260156	CAL120	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.5136552992393795	[810]	[690,832,595]	-6	hSpCas9	negative selection	6100907
52491555	52491578	12	-	27260156	CAL120	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.3804034688236888	[410]	[458,476,254]	-5	hSpCas9	negative selection	6100909
52491111	52491134	12	-	27260156	CAL120	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.6291732273802937	[645]	[623,391,557]	-7	hSpCas9	negative selection	6100915
52491724	52491747	12	-	27260156	CADOES1	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.7141062907209647	[487]	[793,500,900,782]	9	hSpCas9	negative selection	6157903
52491588	52491611	12	-	27260156	CADOES1	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.02530362368024286	[1110]	[1150,987,1140,920]	0	hSpCas9	negative selection	6157904
52492726	52492749	12	+	27260156	CADOES1	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.7473256652438264	[574]	[851,844,1120,767]	9	hSpCas9	negative selection	6157905
52492715	52492738	12	-	27260156	CADOES1	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.5383223395992652	[810]	[466,519,535,555]	-7	hSpCas9	negative selection	6222158
52491555	52491578	12	-	27260156	CADOES1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.2912003693959512	[410]	[404,515,335,619]	5	hSpCas9	negative selection	6222160
52491111	52491134	12	-	27260156	CADOES1	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.02247196598531448	[645]	[649,480,610,624]	0	hSpCas9	negative selection	6222166
52491724	52491747	12	-	27260156	EWS502	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.6651125348882595	[487]	[824,740,1018,685]	9	hSpCas9	negative selection	6279154
52491588	52491611	12	-	27260156	EWS502	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.002700971989580303	[1110]	[967,1143,1365,1249]	0	hSpCas9	negative selection	6279155
52492726	52492749	12	+	27260156	EWS502	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.7654352825046083	[574]	[1033,870,985,1268]	9	hSpCas9	negative selection	6279156
52492715	52492738	12	-	27260156	EWS502	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.42244769600838344	[810]	[607,509,669,793]	-6	hSpCas9	negative selection	6343409
52491555	52491578	12	-	27260156	EWS502	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.11873682601827314	[410]	[458,408,604,417]	2	hSpCas9	negative selection	6343411
52491111	52491134	12	-	27260156	EWS502	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.40967858982991784	[645]	[586,591,416,443]	-6	hSpCas9	negative selection	6343417
52491724	52491747	12	-	27260156	EW8	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5339404108523672	[487]	[718,477,491,628]	8	hSpCas9	negative selection	6400405
52491588	52491611	12	-	27260156	EW8	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.09770953899964407	[1110]	[851,955,632,958]	-2	hSpCas9	negative selection	6400406
52492726	52492749	12	+	27260156	EW8	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.8256740469516238	[574]	[819,824,822,832]	9	hSpCas9	negative selection	6400407
52492715	52492738	12	-	27260156	EW8	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.43146740432132036	[810]	[642,320,422,587]	-7	hSpCas9	negative selection	6464660
52491555	52491578	12	-	27260156	EW8	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.10485367404146134	[410]	[529,425,259,251]	2	hSpCas9	negative selection	6464662
52491111	52491134	12	-	27260156	EW8	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.3526234424805685	[645]	[449,365,433,388]	-6	hSpCas9	negative selection	6464668
52491724	52491747	12	-	27260156	CORL105	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5359221739298974	[487]	[845,841,800,819]	8	hSpCas9	negative selection	6521656
52491588	52491611	12	-	27260156	CORL105	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.011433867608440673	[1110]	[1360,1385,1215,1265]	0	hSpCas9	negative selection	6521657
52492726	52492749	12	+	27260156	CORL105	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.5562318594404164	[574]	[989,1158,906,886]	8	hSpCas9	negative selection	6521658
52492715	52492738	12	-	27260156	CORL105	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.10139125138492644	[810]	[1002,918,1144,1027]	2	hSpCas9	negative selection	6585911
52491555	52491578	12	-	27260156	CORL105	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.05320593119167083	[410]	[524,250,654,459]	-1	hSpCas9	negative selection	6585913
52491111	52491134	12	-	27260156	CORL105	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.32730931908295374	[645]	[568,588,741,531]	-6	hSpCas9	negative selection	6585919
52491724	52491747	12	-	27260156	HS294T	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.418236408266048	[487]	[193,305,246,266]	5	hSpCas9	negative selection	6642907
52491588	52491611	12	-	27260156	HS294T	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.19366462540839335	[1110]	[464,524,522,443]	2	hSpCas9	negative selection	6642908
52492726	52492749	12	+	27260156	HS294T	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.7080070583666295	[574]	[472,403,270,276]	8	hSpCas9	negative selection	6642909
52492715	52492738	12	-	27260156	HS294T	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.4264058688814341	[810]	[187,172,194,412]	-6	hSpCas9	negative selection	6707162
52491555	52491578	12	-	27260156	HS294T	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.660769011890892	[410]	[177,212,162,499]	8	hSpCas9	negative selection	6707164
52491111	52491134	12	-	27260156	HS294T	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.7525682250887853	[645]	[135,128,162,169]	-8	hSpCas9	negative selection	6707170
52491724	52491747	12	-	27260156	HCC44	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5000553697691086	[487]	[754,720,964,714]	8	hSpCas9	negative selection	6764158
52491588	52491611	12	-	27260156	HCC44	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.044813711780167464	[1110]	[1339,987,1555,1379]	0	hSpCas9	negative selection	6764159
52492726	52492749	12	+	27260156	HCC44	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.5865742553692997	[574]	[800,946,1069,1080]	8	hSpCas9	negative selection	6764160
52492715	52492738	12	-	27260156	HCC44	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.23671689572790588	[810]	[733,734,834,813]	-4	hSpCas9	negative selection	6828413
52491555	52491578	12	-	27260156	HCC44	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.005645717332063566	[410]	[586,403,370,502]	0	hSpCas9	negative selection	6828415
52491111	52491134	12	-	27260156	HCC44	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.5167745490936857	[645]	[422,469,674,496]	-6	hSpCas9	negative selection	6828421
52491724	52491747	12	-	27260156	G402	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	1.1920132997155923	[487]	[1122,903,1697,1636]	9	hSpCas9	negative selection	6885409
52491588	52491611	12	-	27260156	G402	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.15876920954416107	[1110]	[1563,1774,1788,968]	2	hSpCas9	negative selection	6885410
52492726	52492749	12	+	27260156	G402	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.951346605775066	[574]	[1418,1747,1347,957]	9	hSpCas9	negative selection	6885411
52492715	52492738	12	-	27260156	G402	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.5031858634323039	[810]	[663,1041,461,639]	-6	hSpCas9	negative selection	6949664
52491555	52491578	12	-	27260156	G402	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.01407878807121421	[410]	[443,606,532,403]	0	hSpCas9	negative selection	6949666
52491111	52491134	12	-	27260156	G402	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.14393981447955634	[645]	[355,1103,734,630]	-2	hSpCas9	negative selection	6949672
52491724	52491747	12	-	27260156	L33	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.4126334464794912	[487]	[598,293,356,713]	8	hSpCas9	negative selection	7006660
52491588	52491611	12	-	27260156	L33	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.06466857100226764	[1110]	[1224,506,737,1010]	1	hSpCas9	negative selection	7006661
52492726	52492749	12	+	27260156	L33	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.6437804218693006	[574]	[855,401,562,861]	9	hSpCas9	negative selection	7006662
52492715	52492738	12	-	27260156	L33	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.1682847592186354	[810]	[776,316,350,774]	-4	hSpCas9	negative selection	7070915
52491555	52491578	12	-	27260156	L33	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.3900398895565089	[410]	[316,147,149,336]	-7	hSpCas9	negative selection	7070917
52491111	52491134	12	-	27260156	L33	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.001963874611228711	[645]	[642,272,404,626]	0	hSpCas9	negative selection	7070923
52491724	52491747	12	-	27260156	K562	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.7551085957783049	[487]	[535,670,1053,649]	8	hSpCas9	negative selection	7127911
52491588	52491611	12	-	27260156	K562	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.3640833504316663	[1110]	[958,1852,1223,1063]	4	hSpCas9	negative selection	7127912
52492726	52492749	12	+	27260156	K562	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	1.0554529925151566	[574]	[1180,842,1254,967]	9	hSpCas9	negative selection	7127913
52492715	52492738	12	-	27260156	K562	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.6150097827547186	[810]	[507,519,494,371]	-6	hSpCas9	negative selection	7192166
52491555	52491578	12	-	27260156	K562	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.12760417780406058	[410]	[568,171,348,492]	1	hSpCas9	negative selection	7192168
52491111	52491134	12	-	27260156	K562	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.3872736653571769	[645]	[421,666,271,404]	-5	hSpCas9	negative selection	7192174
52491724	52491747	12	-	27260156	HT29	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.43245600159902775	[487]	[918,813,720,757]	8	hSpCas9	negative selection	7249162
52491588	52491611	12	-	27260156	HT29	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.0922322241099256	[1110]	[1269,1828,1537,1165]	1	hSpCas9	negative selection	7249163
52492726	52492749	12	+	27260156	HT29	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.7329905050432045	[574]	[1263,1364,1080,976]	9	hSpCas9	negative selection	7249164
52492715	52492738	12	-	27260156	HT29	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.05068736649320238	[810]	[929,895,1052,918]	-1	hSpCas9	negative selection	7313417
52491555	52491578	12	-	27260156	HT29	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.2263041229244022	[410]	[403,476,446,384]	-4	hSpCas9	negative selection	7313419
52491111	52491134	12	-	27260156	HT29	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.03282623181888744	[645]	[862,1081,716,473]	0	hSpCas9	negative selection	7313425
52491724	52491747	12	-	27260156	MHHES1	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.6106307389477765	[487]	[931,964,922,598]	9	hSpCas9	negative selection	7370413
52491588	52491611	12	-	27260156	MHHES1	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.04928424398032316	[1110]	[1481,1321,1555,907]	0	hSpCas9	negative selection	7370414
52492726	52492749	12	+	27260156	MHHES1	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.40560594852341314	[574]	[1319,854,693,646]	7	hSpCas9	negative selection	7370415
52492715	52492738	12	-	27260156	MHHES1	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.09620765960843247	[810]	[811,1037,885,709]	-2	hSpCas9	negative selection	7434668
52491555	52491578	12	-	27260156	MHHES1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.09912793249506871	[410]	[398,528,419,386]	-2	hSpCas9	negative selection	7434670
52491111	52491134	12	-	27260156	MHHES1	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.08600496531366936	[645]	[638,755,802,559]	-1	hSpCas9	negative selection	7434676
52491724	52491747	12	-	27260156	MEWO	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.49586709554233815	[487]	[896,512,570]	8	hSpCas9	negative selection	7491664
52491588	52491611	12	-	27260156	MEWO	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.022925487269706002	[1110]	[1204,1013,977]	0	hSpCas9	negative selection	7491665
52492726	52492749	12	+	27260156	MEWO	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.583645607906353	[574]	[940,702,800]	9	hSpCas9	negative selection	7491666
52492715	52492738	12	-	27260156	MEWO	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.2755767068723415	[810]	[726,565,606]	-6	hSpCas9	negative selection	7555919
52491555	52491578	12	-	27260156	MEWO	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.036127676652571716	[410]	[489,418,237]	-1	hSpCas9	negative selection	7555921
52491111	52491134	12	-	27260156	MEWO	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.14853011730904064	[645]	[566,510,561]	-3	hSpCas9	negative selection	7555927
52491724	52491747	12	-	27260156	LNCAPCLONEFGC	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.7825478352741998	[487]	[711,808,848,681]	9	hSpCas9	negative selection	7612915
52491588	52491611	12	-	27260156	LNCAPCLONEFGC	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.13868628493090118	[1110]	[1040,823,1416,1214]	2	hSpCas9	negative selection	7612916
52492726	52492749	12	+	27260156	LNCAPCLONEFGC	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.7742281910781165	[574]	[820,903,801,1022]	9	hSpCas9	negative selection	7612917
52492715	52492738	12	-	27260156	LNCAPCLONEFGC	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.6816162685709177	[810]	[435,450,513,439]	-7	hSpCas9	negative selection	7677170
52491555	52491578	12	-	27260156	LNCAPCLONEFGC	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.23181551179971407	[410]	[256,423,309,269]	-4	hSpCas9	negative selection	7677172
52491111	52491134	12	-	27260156	LNCAPCLONEFGC	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.6866420073640057	[645]	[314,262,520,385]	-8	hSpCas9	negative selection	7677178
52491724	52491747	12	-	27260156	PANC0327	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.8928710403495679	[487]	[567,616,774,1263]	9	hSpCas9	negative selection	7734166
52491588	52491611	12	-	27260156	PANC0327	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.3661907345511122	[1110]	[851,425,686,1147]	-5	hSpCas9	negative selection	7734167
52492726	52492749	12	+	27260156	PANC0327	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.4092098742243333	[574]	[770,699,749,496]	6	hSpCas9	negative selection	7734168
52492715	52492738	12	-	27260156	PANC0327	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.5636676714863561	[810]	[428,371,689,468]	-7	hSpCas9	negative selection	7798421
52491555	52491578	12	-	27260156	PANC0327	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-1.104642365649621	[410]	[210,110,169,197]	-8	hSpCas9	negative selection	7798423
52491111	52491134	12	-	27260156	PANC0327	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.3204039677804151	[645]	[418,573,427,398]	-5	hSpCas9	negative selection	7798429
52491724	52491747	12	-	27260156	NCIH2009	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.8670599081830805	[487]	[1104,871,1730]	9	hSpCas9	negative selection	7855417
52491588	52491611	12	-	27260156	NCIH2009	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.172592174154387	[1110]	[1602,1594,971]	-2	hSpCas9	negative selection	7855418
52492726	52492749	12	+	27260156	NCIH2009	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.5375020163450885	[574]	[1393,847,1304]	7	hSpCas9	negative selection	7855419
52492715	52492738	12	-	27260156	NCIH2009	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.5089334549137882	[810]	[857,832,707]	-6	hSpCas9	negative selection	7919672
52491555	52491578	12	-	27260156	NCIH2009	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.07418203923713598	[410]	[654,604,395]	-1	hSpCas9	negative selection	7919674
52491111	52491134	12	-	27260156	NCIH2009	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.586591727339436	[645]	[858,438,557]	-6	hSpCas9	negative selection	7919680
52491724	52491747	12	-	27260156	NCIH1373	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.39256479955464624	[487]	[535,764,815,187]	4	hSpCas9	negative selection	7976668
52491588	52491611	12	-	27260156	NCIH1373	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.24160746730438465	[1110]	[1209,1722,1082,479]	2	hSpCas9	negative selection	7976669
52492726	52492749	12	+	27260156	NCIH1373	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	1.2744227064013227	[574]	[1774,1509,1511,384]	9	hSpCas9	negative selection	7976670
52492715	52492738	12	-	27260156	NCIH1373	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-1.4266315549857198	[810]	[577,289,238,74]	-8	hSpCas9	negative selection	8040923
52491555	52491578	12	-	27260156	NCIH1373	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.24332305512738747	[410]	[630,277,385,79]	-2	hSpCas9	negative selection	8040925
52491111	52491134	12	-	27260156	NCIH1373	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.6218960326588019	[645]	[349,404,444,178]	-6	hSpCas9	negative selection	8040931
52491724	52491747	12	-	27260156	PATU8902	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5900538155473483	[487]	[864,619,1275,1289]	6	hSpCas9	negative selection	8097919
52491588	52491611	12	-	27260156	PATU8902	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.08719750148733763	[1110]	[1343,1805,1051,1755]	-1	hSpCas9	negative selection	8097920
52492726	52492749	12	+	27260156	PATU8902	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.6376184552014246	[574]	[1542,1092,717,1820]	6	hSpCas9	negative selection	8097921
52492715	52492738	12	-	27260156	PATU8902	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.43221524976469394	[810]	[749,1410,416,880]	-4	hSpCas9	negative selection	8162174
52491555	52491578	12	-	27260156	PATU8902	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.24871276379815466	[410]	[832,571,564,784]	2	hSpCas9	negative selection	8162176
52491111	52491134	12	-	27260156	PATU8902	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-2.0813904300413237	[645]	[211,431,92,133]	-9	hSpCas9	negative selection	8162182
52491724	52491747	12	-	27260156	PANC1	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.3194624221904413	[487]	[603,715,565,276]	5	hSpCas9	negative selection	8219170
52491588	52491611	12	-	27260156	PANC1	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.3875663434626224	[1110]	[1378,1329,1044,1232]	6	hSpCas9	negative selection	8219171
52492726	52492749	12	+	27260156	PANC1	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.8020932195362774	[574]	[972,967,812,718]	9	hSpCas9	negative selection	8219172
52492715	52492738	12	-	27260156	PANC1	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	0.0630823403834152	[810]	[626,998,829,533]	1	hSpCas9	negative selection	8283425
52491555	52491578	12	-	27260156	PANC1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.0019077161406146903	[410]	[363,512,359,221]	0	hSpCas9	negative selection	8283427
52491111	52491134	12	-	27260156	PANC1	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.10532015090793845	[645]	[418,658,446,553]	-2	hSpCas9	negative selection	8283433
52491724	52491747	12	-	27260156	PANC0813	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.6560281607464425	[487]	[939,913,639,1107]	9	hSpCas9	negative selection	8340421
52491588	52491611	12	-	27260156	PANC0813	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.19489888857519455	[1110]	[1754,1080,1291,1847]	3	hSpCas9	negative selection	8340422
52492726	52492749	12	+	27260156	PANC0813	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.6884479870334727	[574]	[1080,1282,1200,802]	9	hSpCas9	negative selection	8340423
52492715	52492738	12	-	27260156	PANC0813	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.37611277285898176	[810]	[905,811,573,661]	-5	hSpCas9	negative selection	8404676
52491555	52491578	12	-	27260156	PANC0813	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.2702019554222981	[410]	[570,692,594,473]	4	hSpCas9	negative selection	8404678
52491111	52491134	12	-	27260156	PANC0813	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.4787159238853229	[645]	[631,424,607,521]	-6	hSpCas9	negative selection	8404684
52491724	52491747	12	-	27260156	RDES	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.4933525614885485	[487]	[555,760,925,982]	7	hSpCas9	negative selection	8461672
52491588	52491611	12	-	27260156	RDES	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.1286177748350421	[1110]	[1008,1020,1213,1494]	-2	hSpCas9	negative selection	8461673
52492726	52492749	12	+	27260156	RDES	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.8576791242129894	[574]	[918,1100,1215,1663]	9	hSpCas9	negative selection	8461674
52492715	52492738	12	-	27260156	RDES	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.6650458172327085	[810]	[382,681,646,674]	-8	hSpCas9	negative selection	8525927
52491555	52491578	12	-	27260156	RDES	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.19830950552829937	[410]	[389,504,546,785]	3	hSpCas9	negative selection	8525929
52491111	52491134	12	-	27260156	RDES	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.570996632165383	[645]	[509,398,490,606]	-7	hSpCas9	negative selection	8525935
52491724	52491747	12	-	27260156	PC3	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5929199016671831	[487]	[421,658,1038,1020]	9	hSpCas9	negative selection	8582923
52491588	52491611	12	-	27260156	PC3	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.16243868772704007	[1110]	[935,974,2330,1143]	3	hSpCas9	negative selection	8582924
52492726	52492749	12	+	27260156	PC3	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.6068052021725059	[574]	[649,699,1587,839]	9	hSpCas9	negative selection	8582925
52492715	52492738	12	-	27260156	PC3	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.004270520823996815	[810]	[556,665,1329,911]	0	hSpCas9	negative selection	8647178
52491555	52491578	12	-	27260156	PC3	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.22817820015036783	[410]	[284,543,575,592]	5	hSpCas9	negative selection	8647180
52491111	52491134	12	-	27260156	PC3	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	0.08264355710057547	[645]	[455,692,1043,703]	1	hSpCas9	negative selection	8647186
52491724	52491747	12	-	27260156	PATU8988T	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.379379197719224	[487]	[638,524,680,597]	6	hSpCas9	negative selection	8704174
52491588	52491611	12	-	27260156	PATU8988T	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.14910763254298276	[1110]	[952,1288,1167,1375]	2	hSpCas9	negative selection	8704175
52492726	52492749	12	+	27260156	PATU8988T	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.9238087294259586	[574]	[1514,848,867,959]	9	hSpCas9	negative selection	8704176
52492715	52492738	12	-	27260156	PATU8988T	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.3983506602368816	[810]	[535,889,424,553]	-6	hSpCas9	negative selection	8768429
52491555	52491578	12	-	27260156	PATU8988T	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.017392771069147134	[410]	[416,428,429,327]	0	hSpCas9	negative selection	8768431
52491111	52491134	12	-	27260156	PATU8988T	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.3264755874332932	[645]	[651,415,326,598]	-5	hSpCas9	negative selection	8768437
52491724	52491747	12	-	27260156	T47D	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.37309793827719423	[487]	[868,619,724,741]	7	hSpCas9	negative selection	8825425
52491588	52491611	12	-	27260156	T47D	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.04886417274676913	[1110]	[1193,1175,1275,1367]	-1	hSpCas9	negative selection	8825426
52492726	52492749	12	+	27260156	T47D	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.6293996170119754	[574]	[1045,1062,1116,910]	9	hSpCas9	negative selection	8825427
52492715	52492738	12	-	27260156	T47D	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.5855814546599325	[810]	[606,644,627,636]	-8	hSpCas9	negative selection	8889680
52491555	52491578	12	-	27260156	T47D	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.22911634599510997	[410]	[497,300,418,425]	-5	hSpCas9	negative selection	8889682
52491111	52491134	12	-	27260156	T47D	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.1856232682997026	[645]	[748,636,624,637]	-4	hSpCas9	negative selection	8889688
52491724	52491747	12	-	27260156	SU8686	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.6060481107540776	[487]	[675,622,858,820]	8	hSpCas9	negative selection	8946676
52491588	52491611	12	-	27260156	SU8686	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.013880417088712793	[1110]	[857,1172,1001,1485]	0	hSpCas9	negative selection	8946677
52492726	52492749	12	+	27260156	SU8686	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.7978268577339652	[574]	[979,728,1007,1330]	9	hSpCas9	negative selection	8946678
52492715	52492738	12	-	27260156	SU8686	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.6298450782170116	[810]	[427,456,612,612]	-7	hSpCas9	negative selection	9010931
52491555	52491578	12	-	27260156	SU8686	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.023766352234464966	[410]	[325,367,523,462]	0	hSpCas9	negative selection	9010933
52491111	52491134	12	-	27260156	SU8686	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.808035972628206	[645]	[374,364,341,378]	-8	hSpCas9	negative selection	9010939
52491724	52491747	12	-	27260156	SKES1	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.6491311362118587	[487]	[709,1055,679,642]	9	hSpCas9	negative selection	9067927
52491588	52491611	12	-	27260156	SKES1	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.11125500562675228	[1110]	[1136,1239,1003,782]	-2	hSpCas9	negative selection	9067928
52492726	52492749	12	+	27260156	SKES1	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.5497134234836281	[574]	[953,872,889,671]	9	hSpCas9	negative selection	9067929
52492715	52492738	12	-	27260156	SKES1	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.6529411112312153	[810]	[526,588,523,432]	-8	hSpCas9	negative selection	9132182
52491555	52491578	12	-	27260156	SKES1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.16238904348730956	[410]	[380,487,381,241]	-4	hSpCas9	negative selection	9132184
52491111	52491134	12	-	27260156	SKES1	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.12490234129094291	[645]	[642,668,620,456]	-3	hSpCas9	negative selection	9132190
52491724	52491747	12	-	27260156	TOV112D	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5792952348634703	[487]	[1096,714,514,622]	9	hSpCas9	negative selection	9189178
52491588	52491611	12	-	27260156	TOV112D	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.010771628241757591	[1110]	[1162,1531,1022,875]	0	hSpCas9	negative selection	9189179
52492726	52492749	12	+	27260156	TOV112D	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.7235563881360455	[574]	[760,1646,870,685]	9	hSpCas9	negative selection	9189180
52492715	52492738	12	-	27260156	TOV112D	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.17950537721772586	[810]	[791,874,497,746]	-4	hSpCas9	negative selection	9253433
52491555	52491578	12	-	27260156	TOV112D	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.413564490968502	[410]	[459,195,307,257]	-7	hSpCas9	negative selection	9253435
52491111	52491134	12	-	27260156	TOV112D	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.04448926714459894	[645]	[627,788,604,528]	-1	hSpCas9	negative selection	9253441
52491724	52491747	12	-	27260156	TC71	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.4545043807581512	[487]	[586,835,686,763]	9	hSpCas9	negative selection	9310429
52491588	52491611	12	-	27260156	TC71	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	0.001170866956786476	[1110]	[1188,1338,1112,1124]	0	hSpCas9	negative selection	9310430
52492726	52492749	12	+	27260156	TC71	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	0.36456549727981546	[574]	[825,806,737,804]	8	hSpCas9	negative selection	9310431
52492715	52492738	12	-	27260156	TC71	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.1249423512738812	[810]	[724,853,752,863]	-3	hSpCas9	negative selection	9374684
52491555	52491578	12	-	27260156	TC71	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.2591855257242536	[410]	[413,336,361,357]	-6	hSpCas9	negative selection	9374686
52491111	52491134	12	-	27260156	TC71	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.049426268529672246	[645]	[611,780,552,739]	-1	hSpCas9	negative selection	9374692
52491724	52491747	12	-	27260156	TC32	viability	TCTCTTTCAGGTGCGGTTCCTGG	KRT6A	ENSG00000205420	0.5590476508851986	[487]	[603,452,922,828]	8	hSpCas9	negative selection	9431680
52491588	52491611	12	-	27260156	TC32	viability	AGGCAGCTGGACAGCATTGTCGG	KRT6A	ENSG00000205420	-0.0801561658892409	[1110]	[887,760,1174,1210]	-1	hSpCas9	negative selection	9431681
52492726	52492749	12	+	27260156	TC32	viability	TGGGATCGATTTGCAGGTTGAGG	KRT6A	ENSG00000205420	1.0738407496495705	[574]	[883,1222,1440,969]	9	hSpCas9	negative selection	9431682
52492715	52492738	12	-	27260156	TC32	viability	AAATCGATCCCACCATCCAGCGG	KRT6A	ENSG00000205420	-0.29069415476068045	[810]	[559,465,833,703]	-5	hSpCas9	negative selection	9495935
52491555	52491578	12	-	27260156	TC32	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.022804721333497202	[410]	[261,463,384,421]	0	hSpCas9	negative selection	9495937
52491111	52491134	12	-	27260156	TC32	viability	TGAATTTGTGACTCTGAAGAAGG	KRT6A	ENSG00000205420	-0.17744600667516225	[645]	[611,310,756,550]	-3	hSpCas9	negative selection	9495943
52491586	52491609	12	-	28162770	P31FUJ	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.5789686838730902	[232]	[408]	6	hSpCas9	negative selection	10181565
52487894	52487917	12	+	28162770	P31FUJ	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.36797845908952764	[1027]	[1558]	4	hSpCas9	negative selection	10181566
52491538	52491561	12	-	28162770	P31FUJ	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-0.01283652047247097	[84]	[98]	0	hSpCas9	negative selection	10181567
52491692	52491715	12	-	28162770	P31FUJ	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.2375571746669215	[274]	[380]	2	hSpCas9	negative selection	10181568
52491679	52491702	12	-	28162770	P31FUJ	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.559684550587944	[208]	[361]	6	hSpCas9	negative selection	10181569
52492702	52492725	12	-	28162770	P31FUJ	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.27884361866385654	[147]	[210]	3	hSpCas9	negative selection	10181570
52491555	52491578	12	-	28162770	P31FUJ	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.5991899971375998	[281]	[501]	6	hSpCas9	negative selection	10181571
52488522	52488545	12	+	28162770	P31FUJ	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	-0.7824892303880043	[201]	[137]	-6	hSpCas9	negative selection	10181572
52488335	52488358	12	-	28162770	P31FUJ	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	1.1994250561619804	[364]	[984]	9	hSpCas9	negative selection	10181573
52491586	52491609	12	-	28162770	TF1	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	NaN	[NaN]	[306]	1	hSpCas9	negative selection	10350931
52487894	52487917	12	+	28162770	TF1	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	NaN	[NaN]	[933]	1	hSpCas9	negative selection	10350932
52491538	52491561	12	-	28162770	TF1	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	NaN	[NaN]	[5]	1	hSpCas9	negative selection	10350933
52491692	52491715	12	-	28162770	TF1	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	NaN	[NaN]	[270]	1	hSpCas9	negative selection	10350934
52491679	52491702	12	-	28162770	TF1	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	NaN	[NaN]	[245]	1	hSpCas9	negative selection	10350935
52492702	52492725	12	-	28162770	TF1	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10350936
52491555	52491578	12	-	28162770	TF1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	NaN	[NaN]	[335]	1	hSpCas9	negative selection	10350937
52488522	52488545	12	+	28162770	TF1	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10350938
52488335	52488358	12	-	28162770	TF1	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	NaN	[NaN]	[337]	1	hSpCas9	negative selection	10350939
52491586	52491609	12	-	28162770	SKM1	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.699535422557517	[61]	[177]	6	hSpCas9	negative selection	10520297
52487894	52487917	12	+	28162770	SKM1	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.778390843268757	[185]	[563]	7	hSpCas9	negative selection	10520298
52491538	52491561	12	-	28162770	SKM1	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-1.572023445013658	[36]	[21]	-8	hSpCas9	negative selection	10520299
52491692	52491715	12	-	28162770	SKM1	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.281091794942098	[53]	[115]	2	hSpCas9	negative selection	10520300
52491679	52491702	12	-	28162770	SKM1	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.3120911975652773	[76]	[168]	3	hSpCas9	negative selection	10520301
52492702	52492725	12	-	28162770	SKM1	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.6325641654434757	[26]	[73]	6	hSpCas9	negative selection	10520302
52491555	52491578	12	-	28162770	SKM1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.8033185403152916	[46]	[144]	7	hSpCas9	negative selection	10520303
52488522	52488545	12	+	28162770	SKM1	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.08242064199576338	[38]	[72]	0	hSpCas9	negative selection	10520304
52488335	52488358	12	-	28162770	SKM1	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.33257533908687087	[83]	[186]	3	hSpCas9	negative selection	10520305
52491586	52491609	12	-	28162770	SKM1	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.699535422557517	[61]	[177]	6	hSpCas9	negative selection	10689663
52487894	52487917	12	+	28162770	SKM1	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.778390843268757	[185]	[563]	7	hSpCas9	negative selection	10689664
52491538	52491561	12	-	28162770	SKM1	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-1.572023445013658	[36]	[21]	-8	hSpCas9	negative selection	10689665
52491692	52491715	12	-	28162770	SKM1	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.281091794942098	[53]	[115]	2	hSpCas9	negative selection	10689666
52491679	52491702	12	-	28162770	SKM1	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.3120911975652773	[76]	[168]	3	hSpCas9	negative selection	10689667
52492702	52492725	12	-	28162770	SKM1	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.6325641654434757	[26]	[73]	6	hSpCas9	negative selection	10689668
52491555	52491578	12	-	28162770	SKM1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.8033185403152916	[46]	[144]	7	hSpCas9	negative selection	10689669
52488522	52488545	12	+	28162770	SKM1	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.08242064199576338	[38]	[72]	0	hSpCas9	negative selection	10689670
52488335	52488358	12	-	28162770	SKM1	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.33257533908687087	[83]	[186]	3	hSpCas9	negative selection	10689671
52491586	52491609	12	-	28162770	PL21	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	-0.2830693874311028	[259]	[92]	-2	hSpCas9	negative selection	10859029
52487894	52487917	12	+	28162770	PL21	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.768256443772553	[602]	[446]	6	hSpCas9	negative selection	10859030
52491538	52491561	12	-	28162770	PL21	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	1.7046121973501085	[85]	[121]	9	hSpCas9	negative selection	10859031
52491692	52491715	12	-	28162770	PL21	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.8151146842769158	[221]	[169]	7	hSpCas9	negative selection	10859032
52491679	52491702	12	-	28162770	PL21	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.5093824497455675	[296]	[183]	4	hSpCas9	negative selection	10859033
52492702	52492725	12	-	28162770	PL21	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	-0.870249713402078	[104]	[24]	-5	hSpCas9	negative selection	10859034
52491555	52491578	12	-	28162770	PL21	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	1.4620340004764452	[210]	[252]	9	hSpCas9	negative selection	10859035
52488522	52488545	12	+	28162770	PL21	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	1.1207051469949154	[111]	[105]	8	hSpCas9	negative selection	10859036
52488335	52488358	12	-	28162770	PL21	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	-0.1730138037532153	[214]	[82]	-1	hSpCas9	negative selection	10859037
52491586	52491609	12	-	28162770	P31FUJ	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.5789686838730902	[232]	[408]	6	hSpCas9	negative selection	11028395
52487894	52487917	12	+	28162770	P31FUJ	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.36797845908952764	[1027]	[1558]	4	hSpCas9	negative selection	11028396
52491538	52491561	12	-	28162770	P31FUJ	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-0.01283652047247097	[84]	[98]	0	hSpCas9	negative selection	11028397
52491692	52491715	12	-	28162770	P31FUJ	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.2375571746669215	[274]	[380]	2	hSpCas9	negative selection	11028398
52491679	52491702	12	-	28162770	P31FUJ	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.559684550587944	[208]	[361]	6	hSpCas9	negative selection	11028399
52492702	52492725	12	-	28162770	P31FUJ	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.27884361866385654	[147]	[210]	3	hSpCas9	negative selection	11028400
52491555	52491578	12	-	28162770	P31FUJ	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.5991899971375998	[281]	[501]	6	hSpCas9	negative selection	11028401
52488522	52488545	12	+	28162770	P31FUJ	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	-0.7824892303880043	[201]	[137]	-6	hSpCas9	negative selection	11028402
52488335	52488358	12	-	28162770	P31FUJ	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	1.1994250561619804	[364]	[984]	9	hSpCas9	negative selection	11028403
52491586	52491609	12	-	28162770	OCIAML5	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.5910139655966502	[120]	[328]	5	hSpCas9	negative selection	11197761
52487894	52487917	12	+	28162770	OCIAML5	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.6571607142728351	[364]	[1038]	6	hSpCas9	negative selection	11197762
52491538	52491561	12	-	28162770	OCIAML5	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	0.3958609425795885	[39]	[94]	3	hSpCas9	negative selection	11197763
52491692	52491715	12	-	28162770	OCIAML5	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.3307974862858134	[110]	[251]	3	hSpCas9	negative selection	11197764
52491679	52491702	12	-	28162770	OCIAML5	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.5257147587568829	[151]	[394]	4	hSpCas9	negative selection	11197765
52492702	52492725	12	-	28162770	OCIAML5	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.762339707749641	[96]	[296]	6	hSpCas9	negative selection	11197766
52491555	52491578	12	-	28162770	OCIAML5	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.6930949217991842	[146]	[428]	6	hSpCas9	negative selection	11197767
52488522	52488545	12	+	28162770	OCIAML5	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	-0.05781523608057326	[78]	[136]	0	hSpCas9	negative selection	11197768
52488335	52488358	12	-	28162770	OCIAML5	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.5526879551529862	[263]	[698]	5	hSpCas9	negative selection	11197769
52491586	52491609	12	-	28162770	EOL1	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	-0.32250670400018255	[412]	[173]	-2	hSpCas9	negative selection	11367127
52487894	52487917	12	+	28162770	EOL1	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.696041048865012	[866]	[739]	6	hSpCas9	negative selection	11367128
52491538	52491561	12	-	28162770	EOL1	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-0.05817423699762991	[165]	[83]	0	hSpCas9	negative selection	11367129
52491692	52491715	12	-	28162770	EOL1	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.7448417493356368	[332]	[293]	6	hSpCas9	negative selection	11367130
52491679	52491702	12	-	28162770	EOL1	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.9214418607027128	[464]	[463]	7	hSpCas9	negative selection	11367131
52492702	52492725	12	-	28162770	EOL1	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.4249767620800228	[122]	[86]	4	hSpCas9	negative selection	11367132
52491555	52491578	12	-	28162770	EOL1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.41912403583458524	[246]	[173]	4	hSpCas9	negative selection	11367133
52488522	52488545	12	+	28162770	EOL1	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	-0.1790748595036229	[201]	[93]	-1	hSpCas9	negative selection	11367134
52488335	52488358	12	-	28162770	EOL1	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.8308623260291006	[333]	[312]	7	hSpCas9	negative selection	11367135
52491586	52491609	12	-	28162770	MOLM13	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.598434849980134	[358]	[392]	4	hSpCas9	negative selection	11536493
52487894	52487917	12	+	28162770	MOLM13	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	1.0452306546064667	[948]	[1415]	7	hSpCas9	negative selection	11536494
52491538	52491561	12	-	28162770	MOLM13	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	0.88588019821277	[121]	[162]	6	hSpCas9	negative selection	11536495
52491692	52491715	12	-	28162770	MOLM13	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.17672260762273362	[357]	[228]	-1	hSpCas9	negative selection	11536496
52491679	52491702	12	-	28162770	MOLM13	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.19104917618575457	[377]	[311]	1	hSpCas9	negative selection	11536497
52492702	52492725	12	-	28162770	MOLM13	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.9185507905541441	[89]	[122]	7	hSpCas9	negative selection	11536498
52491555	52491578	12	-	28162770	MOLM13	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.6667183311103472	[290]	[333]	5	hSpCas9	negative selection	11536499
52488522	52488545	12	+	28162770	MOLM13	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.4612562892121319	[217]	[216]	3	hSpCas9	negative selection	11536500
52488335	52488358	12	-	28162770	MOLM13	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.16146238019740433	[323]	[261]	1	hSpCas9	negative selection	11536501
52491586	52491609	12	-	28162770	HEL	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.4195804456653543	[313]	[268]	3	hSpCas9	negative selection	11705859
52487894	52487917	12	+	28162770	HEL	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.6367066488253155	[718]	[715]	5	hSpCas9	negative selection	11705860
52491538	52491561	12	-	28162770	HEL	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	1.5726603962642163	[115]	[220]	9	hSpCas9	negative selection	11705861
52491692	52491715	12	-	28162770	HEL	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.06691941617011365	[313]	[191]	0	hSpCas9	negative selection	11705862
52491679	52491702	12	-	28162770	HEL	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.9917787725049608	[368]	[469]	8	hSpCas9	negative selection	11705863
52492702	52492725	12	-	28162770	HEL	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.12120171142083458	[88]	[61]	1	hSpCas9	negative selection	11705864
52491555	52491578	12	-	28162770	HEL	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.9211652882511328	[201]	[244]	7	hSpCas9	negative selection	11705865
52488522	52488545	12	+	28162770	HEL	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.2426516741874848	[127]	[96]	2	hSpCas9	negative selection	11705866
52488335	52488358	12	-	28162770	HEL	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.12816565917059852	[299]	[209]	1	hSpCas9	negative selection	11705867
52491586	52491609	12	-	28162770	MV411	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.9279777114861627	[218]	[350]	8	hSpCas9	negative selection	11875225
52487894	52487917	12	+	28162770	MV411	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.4589416559764872	[607]	[703]	4	hSpCas9	negative selection	11875226
52491538	52491561	12	-	28162770	MV411	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	0.587512992380397	[78]	[99]	5	hSpCas9	negative selection	11875227
52491692	52491715	12	-	28162770	MV411	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	1.1163986907589716	[166]	[304]	8	hSpCas9	negative selection	11875228
52491679	52491702	12	-	28162770	MV411	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.4335888666396709	[333]	[379]	4	hSpCas9	negative selection	11875229
52492702	52492725	12	-	28162770	MV411	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.6249116371051358	[106]	[138]	5	hSpCas9	negative selection	11875230
52491555	52491578	12	-	28162770	MV411	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	1.5509283974134611	[125]	[310]	9	hSpCas9	negative selection	11875231
52488522	52488545	12	+	28162770	MV411	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.668901319221052	[111]	[149]	6	hSpCas9	negative selection	11875232
52488335	52488358	12	-	28162770	MV411	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.9749116959716838	[182]	[302]	8	hSpCas9	negative selection	11875233
52491586	52491609	12	-	28162770	MONOMAC1	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.4119425347801379	[138]	[211]	4	hSpCas9	negative selection	12044591
52487894	52487917	12	+	28162770	MONOMAC1	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.2640970668087441	[384]	[529]	2	hSpCas9	negative selection	12044592
52491538	52491561	12	-	28162770	MONOMAC1	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	-0.22350905842074464	[54]	[53]	-2	hSpCas9	negative selection	12044593
52491692	52491715	12	-	28162770	MONOMAC1	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.07598164734686214	[95]	[115]	0	hSpCas9	negative selection	12044594
52491679	52491702	12	-	28162770	MONOMAC1	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.3105006817164364	[184]	[262]	3	hSpCas9	negative selection	12044595
52492702	52492725	12	-	28162770	MONOMAC1	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	-0.35231507253746464	[48]	[43]	-3	hSpCas9	negative selection	12044596
52491555	52491578	12	-	28162770	MONOMAC1	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	-0.8870813938382673	[120]	[74]	-6	hSpCas9	negative selection	12044597
52488522	52488545	12	+	28162770	MONOMAC1	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.22329495188880322	[67]	[90]	2	hSpCas9	negative selection	12044598
52488335	52488358	12	-	28162770	MONOMAC1	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.5399287471066525	[164]	[274]	5	hSpCas9	negative selection	12044599
52491586	52491609	12	-	28162770	OCIAML2	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	0.5182866756288226	[48]	[388]	5	hSpCas9	negative selection	12213957
52487894	52487917	12	+	28162770	OCIAML2	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.1722800246882743	[121]	[761]	1	hSpCas9	negative selection	12213958
52491538	52491561	12	-	28162770	OCIAML2	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	1.1814468713375321	[20]	[263]	9	hSpCas9	negative selection	12213959
52491692	52491715	12	-	28162770	OCIAML2	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	0.7266716151314563	[28]	[265]	7	hSpCas9	negative selection	12213960
52491679	52491702	12	-	28162770	OCIAML2	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	0.20396988796367121	[64]	[414]	2	hSpCas9	negative selection	12213961
52492702	52492725	12	-	28162770	OCIAML2	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.5997595026492369	[14]	[125]	6	hSpCas9	negative selection	12213962
52491555	52491578	12	-	28162770	OCIAML2	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	1.0395649070770228	[32]	[375]	8	hSpCas9	negative selection	12213963
52488522	52488545	12	+	28162770	OCIAML2	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	0.5649940844885601	[34]	[286]	5	hSpCas9	negative selection	12213964
52488335	52488358	12	-	28162770	OCIAML2	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.2589562385584475	[48]	[324]	2	hSpCas9	negative selection	12213965
52491586	52491609	12	-	28162770	OCIAML3	viability	GCAGCTGGACAGCATTGTCGGGG	KRT6A	ENSG00000205420	1.2492668559883837	[67]	[487]	9	hSpCas9	negative selection	12383323
52487894	52487917	12	+	28162770	OCIAML3	viability	TAAGCCACTGCCGACACCACTGG	KRT6A	ENSG00000205420	0.4848067428526657	[186]	[789]	4	hSpCas9	negative selection	12383324
52491538	52491561	12	-	28162770	OCIAML3	viability	CAGAGGCATGCAGGACCTGGTGG	KRT6A	ENSG00000205420	0.5315232417596957	[21]	[95]	5	hSpCas9	negative selection	12383325
52491692	52491715	12	-	28162770	OCIAML3	viability	ACAAGGTTCTGGAAACAAAGTGG	KRT6A	ENSG00000205420	-0.8951771750447282	[68]	[111]	-6	hSpCas9	negative selection	12383326
52491679	52491702	12	-	28162770	OCIAML3	viability	AACAAAGTGGACCCTGCTGCAGG	KRT6A	ENSG00000205420	-0.47853042290422715	[71]	[155]	-4	hSpCas9	negative selection	12383327
52492702	52492725	12	-	28162770	OCIAML3	viability	CATCCAGCGGGTGCGGGCTGAGG	KRT6A	ENSG00000205420	0.8174186054023017	[24]	[132]	7	hSpCas9	negative selection	12383328
52491555	52491578	12	-	28162770	OCIAML3	viability	CGCCTGGACTCAGAGCTCAGAGG	KRT6A	ENSG00000205420	0.14745934607698374	[63]	[213]	1	hSpCas9	negative selection	12383329
52488522	52488545	12	+	28162770	OCIAML3	viability	AGCAATGGCGGCCTGCAGGTTGG	KRT6A	ENSG00000205420	-0.1789701410453195	[20]	[55]	-1	hSpCas9	negative selection	12383330
52488335	52488358	12	-	28162770	OCIAML3	viability	CCGCAAGCTGCTGGAGGGTGAGG	KRT6A	ENSG00000205420	0.611366197122439	[66]	[308]	5	hSpCas9	negative selection	12383331