Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:121391
• Symbol:KRT74
• Description:keratin 74

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT74

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52568329	52568352	12	-	26472758	Jiyoye	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	1.2473949374691042	[123]	[221]	7	hSpCas9	negative selection	86664
52572452	52572475	12	-	26472758	Jiyoye	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.2747250854822241	[284]	[259]	2	hSpCas9	negative selection	86665
52567651	52567674	12	+	26472758	Jiyoye	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	0.5140905854223852	[12]	[13]	4	hSpCas9	negative selection	86666
52573746	52573769	12	-	26472758	Jiyoye	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.4071753815058735	[152]	[152]	3	hSpCas9	negative selection	86667
52573693	52573716	12	-	26472758	Jiyoye	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	-0.1777871192152827	[107]	[71]	-1	hSpCas9	negative selection	86668
52573372	52573395	12	-	26472758	Jiyoye	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.5515652908410482	[132]	[146]	4	hSpCas9	negative selection	86669
52573613	52573636	12	-	26472758	Jiyoye	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.31483987119436113	[159]	[96]	-2	hSpCas9	negative selection	86670
52573420	52573443	12	+	26472758	Jiyoye	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	1.7856870047596032	[19]	[51]	8	hSpCas9	negative selection	86671
52572517	52572540	12	-	26472758	Jiyoye	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.05837158062711656	[148]	[116]	0	hSpCas9	negative selection	86672
52572466	52572489	12	-	26472758	Jiyoye	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.05377694801941546	[335]	[262]	0	hSpCas9	negative selection	86673
52568329	52568352	12	-	26472758	KBM7	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.41809989760397664	[784,557]	[451,384]	4	hSpCas9	negative selection	277782
52572452	52572475	12	-	26472758	KBM7	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.37981455652764295	[1469,1231]	[990,672]	4	hSpCas9	negative selection	277783
52567651	52567674	12	+	26472758	KBM7	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-0.7648944086442824	[68,47]	[25,6]	-6	hSpCas9	negative selection	277784
52573746	52573769	12	-	26472758	KBM7	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.6011265120920584	[637,680]	[771,207]	6	hSpCas9	negative selection	277785
52573693	52573716	12	-	26472758	KBM7	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	0.9080696915256676	[527,373]	[639,171]	8	hSpCas9	negative selection	277786
52573372	52573395	12	-	26472758	KBM7	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.6663923524568724	[424,415]	[390,246]	7	hSpCas9	negative selection	277787
52573613	52573636	12	-	26472758	KBM7	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.4245804137371953	[479,533]	[189,169]	-4	hSpCas9	negative selection	277788
52573420	52573443	12	+	26472758	KBM7	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	1.0328346426470125	[338,282]	[299,295]	9	hSpCas9	negative selection	277789
52572517	52572540	12	-	26472758	KBM7	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.12996459037207153	[843,1000]	[507,456]	1	hSpCas9	negative selection	277790
52572466	52572489	12	-	26472758	KBM7	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.5150464348302346	[1158,1132]	[916,643]	5	hSpCas9	negative selection	277791
52568329	52568352	12	-	26472758	Raji	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.9431949034804317	[250]	[111]	8	hSpCas9	negative selection	468900
52572452	52572475	12	-	26472758	Raji	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	-0.15975208667338348	[774]	[160]	-1	hSpCas9	negative selection	468901
52567651	52567674	12	+	26472758	Raji	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	1.3188876405673113	[18]	[10]	9	hSpCas9	negative selection	468902
52573746	52573769	12	-	26472758	Raji	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.3601496057535664	[281]	[83]	3	hSpCas9	negative selection	468903
52573693	52573716	12	-	26472758	Raji	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	0.07763619197954752	[146]	[35]	0	hSpCas9	negative selection	468904
52573372	52573395	12	-	26472758	Raji	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.3879357024654227	[190]	[57]	3	hSpCas9	negative selection	468905
52573613	52573636	12	-	26472758	Raji	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.3762956295103751	[329]	[58]	-3	hSpCas9	negative selection	468906
52573420	52573443	12	+	26472758	Raji	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	0.8528107082880019	[135]	[56]	7	hSpCas9	negative selection	468907
52572517	52572540	12	-	26472758	Raji	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	-0.30051778262361584	[604]	[113]	-3	hSpCas9	negative selection	468908
52572466	52572489	12	-	26472758	Raji	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	-0.3144781630191762	[776]	[144]	-3	hSpCas9	negative selection	468909
52568329	52568352	12	-	26472758	K562	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	-0.7155409121322022	[532]	[273]	-4	hSpCas9	negative selection	660018
52572452	52572475	12	-	26472758	K562	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	-0.7518773035701344	[1166]	[584]	-4	hSpCas9	negative selection	660019
52567651	52567674	12	+	26472758	K562	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-0.27263970855290554	[82]	[57]	-2	hSpCas9	negative selection	660020
52573746	52573769	12	-	26472758	K562	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	-0.09744329458967416	[582]	[459]	0	hSpCas9	negative selection	660021
52573693	52573716	12	-	26472758	K562	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	0.24441872766644682	[306]	[306]	1	hSpCas9	negative selection	660022
52573372	52573395	12	-	26472758	K562	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.5950075192184485	[308]	[393]	5	hSpCas9	negative selection	660023
52573613	52573636	12	-	26472758	K562	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.4706043136190823	[434]	[264]	-3	hSpCas9	negative selection	660024
52573420	52573443	12	+	26472758	K562	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	-1.2393970495978097	[178]	[63]	-6	hSpCas9	negative selection	660025
52572517	52572540	12	-	26472758	K562	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	-0.3145485645217646	[824]	[559]	-2	hSpCas9	negative selection	660026
52572466	52572489	12	-	26472758	K562	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	1.0351103200924683	[932]	[1613]	8	hSpCas9	negative selection	660027
52567016	52567039	12	-	26627737	DLD1	viability	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	5.995602692838348	[0]	[14,47,0]	9	hSpCas9	negative selection	784253
52567110	52567133	12	+	26627737	DLD1	viability	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.42426726843687096	[468]	[100,234,247]	4	hSpCas9	negative selection	784254
52569885	52569908	12	+	26627737	DLD1	viability	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.2899410854046956	[437]	[241,125,136]	3	hSpCas9	negative selection	784255
52571424	52571447	12	-	26627737	DLD1	viability	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.4244552579660126	[599]	[372,185,200]	4	hSpCas9	negative selection	784256
52573545	52573568	12	-	26627737	DLD1	viability	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.3397636320311208	[129]	[64,15,68]	3	hSpCas9	negative selection	784257
52573657	52573680	12	-	26627737	DLD1	viability	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	-0.06491847811619467	[1391]	[641,275,335]	0	hSpCas9	negative selection	784258
52567016	52567039	12	-	26627737	GBM cells	viability after 5 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	-0.37410461952073026	[28]	[9,13]	-5	hSpCas9	negative selection	866568
52567110	52567133	12	+	26627737	GBM cells	viability after 5 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.05091696833073561	[314]	[163,185]	0	hSpCas9	negative selection	866569
52569885	52569908	12	+	26627737	GBM cells	viability after 5 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.638520255752885	[208]	[63,79]	-7	hSpCas9	negative selection	866570
52571424	52571447	12	-	26627737	GBM cells	viability after 5 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.16643986310841397	[428]	[200,208]	-3	hSpCas9	negative selection	866571
52573545	52573568	12	-	26627737	GBM cells	viability after 5 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.014391092305621633	[35]	[20,17]	0	hSpCas9	negative selection	866572
52573657	52573680	12	-	26627737	GBM cells	viability after 5 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.22796138167321822	[565]	[350,359]	3	hSpCas9	negative selection	866573
52567016	52567039	12	-	26627737	GBM cells	viability after 13 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	-0.45047221550842353	[28]	[5,15]	-5	hSpCas9	negative selection	948883
52567110	52567133	12	+	26627737	GBM cells	viability after 13 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.40147728267202687	[314]	[281,179]	5	hSpCas9	negative selection	948884
52569885	52569908	12	+	26627737	GBM cells	viability after 13 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.5746789166449006	[208]	[79,72]	-6	hSpCas9	negative selection	948885
52571424	52571447	12	-	26627737	GBM cells	viability after 13 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.7046408489157554	[428]	[133,149]	-7	hSpCas9	negative selection	948886
52573545	52573568	12	-	26627737	GBM cells	viability after 13 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.6411753858650027	[35]	[62,3]	7	hSpCas9	negative selection	948887
52573657	52573680	12	-	26627737	GBM cells	viability after 13 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.13291601229851957	[565]	[360,316]	1	hSpCas9	negative selection	948888
52567016	52567039	12	-	26627737	GBM cells	viability after 21 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	1.0222523044880862	[28]	[31,31]	8	hSpCas9	negative selection	1031198
52567110	52567133	12	+	26627737	GBM cells	viability after 21 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.16757320712293533	[314]	[198,185]	1	hSpCas9	negative selection	1031199
52569885	52569908	12	+	26627737	GBM cells	viability after 21 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.20764256745295473	[208]	[139,122]	2	hSpCas9	negative selection	1031200
52571424	52571447	12	-	26627737	GBM cells	viability after 21 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.14654340626774542	[428]	[220,200]	-1	hSpCas9	negative selection	1031201
52573545	52573568	12	-	26627737	GBM cells	viability after 21 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.27474136036068275	[35]	[23,8]	-3	hSpCas9	negative selection	1031202
52573657	52573680	12	-	26627737	GBM cells	viability after 21 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.6046376121602584	[565]	[500,436]	6	hSpCas9	negative selection	1031203
52567016	52567039	12	-	26627737	RPE1	viability after 9 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	4.732103324783985	[11]	[84,118]	9	hSpCas9	negative selection	1113513
52567110	52567133	12	+	26627737	RPE1	viability after 9 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	1.3960360419040618	[438]	[245,510]	7	hSpCas9	negative selection	1113514
52569885	52569908	12	+	26627737	RPE1	viability after 9 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.9387487155588417	[606]	[310,432]	6	hSpCas9	negative selection	1113515
52571424	52571447	12	-	26627737	RPE1	viability after 9 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.068234544221483	[1362]	[418,483]	0	hSpCas9	negative selection	1113516
52573545	52573568	12	-	26627737	RPE1	viability after 9 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	1.146385218074958	[58]	[46,32]	7	hSpCas9	negative selection	1113517
52573657	52573680	12	-	26627737	RPE1	viability after 9 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.09667025988939404	[2313]	[630,959]	0	hSpCas9	negative selection	1113518
52567016	52567039	12	-	26627737	RPE1	viability after 12 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	4.391928377247247	[11]	[90,42]	9	hSpCas9	negative selection	1195828
52567110	52567133	12	+	26627737	RPE1	viability after 12 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.7496790788126596	[438]	[140,258]	5	hSpCas9	negative selection	1195829
52569885	52569908	12	+	26627737	RPE1	viability after 12 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.964478265769501	[606]	[342,291]	6	hSpCas9	negative selection	1195830
52571424	52571447	12	-	26627737	RPE1	viability after 12 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.10161237740102291	[1362]	[423,359]	0	hSpCas9	negative selection	1195831
52573545	52573568	12	-	26627737	RPE1	viability after 12 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	1.62058727668462	[58]	[73,21]	8	hSpCas9	negative selection	1195832
52573657	52573680	12	-	26627737	RPE1	viability after 12 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	-0.055991135353914645	[2313]	[632,560]	0	hSpCas9	negative selection	1195833
52567016	52567039	12	-	26627737	RPE1	viability after 15 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	4.253166116339596	[11]	[107,22]	9	hSpCas9	negative selection	1278143
52567110	52567133	12	+	26627737	RPE1	viability after 15 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	1.5058917710818056	[438]	[229,470]	7	hSpCas9	negative selection	1278144
52569885	52569908	12	+	26627737	RPE1	viability after 15 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	1.2008965318481888	[606]	[353,433]	7	hSpCas9	negative selection	1278145
52571424	52571447	12	-	26627737	RPE1	viability after 15 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.24260353734851348	[1362]	[472,183]	-1	hSpCas9	negative selection	1278146
52573545	52573568	12	-	26627737	RPE1	viability after 15 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	1.8831586388905557	[58]	[85,37]	8	hSpCas9	negative selection	1278147
52573657	52573680	12	-	26627737	RPE1	viability after 15 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.027059951828568574	[2313]	[780,556]	0	hSpCas9	negative selection	1278148
52567016	52567039	12	-	26627737	RPE1	viability after 18 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	3.2814429286347777	[11]	[1,62]	9	hSpCas9	negative selection	1360458
52567110	52567133	12	+	26627737	RPE1	viability after 18 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	1.2707689961555664	[438]	[208,367]	7	hSpCas9	negative selection	1360459
52569885	52569908	12	+	26627737	RPE1	viability after 18 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	1.5397087820911772	[606]	[541,405]	7	hSpCas9	negative selection	1360460
52571424	52571447	12	-	26627737	RPE1	viability after 18 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.1369063275703516	[1362]	[451,208]	-1	hSpCas9	negative selection	1360461
52573545	52573568	12	-	26627737	RPE1	viability after 18 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	1.2587263572561946	[58]	[40,34]	7	hSpCas9	negative selection	1360462
52573657	52573680	12	-	26627737	RPE1	viability after 18 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	-0.09477320249731047	[2313]	[446,731]	0	hSpCas9	negative selection	1360463
52567016	52567039	12	-	26627737	HeLa	viability after 8 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	0.43955061292812925	[64]	[72,0,47]	4	hSpCas9	negative selection	1442773
52567110	52567133	12	+	26627737	HeLa	viability after 8 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.13850482175152495	[384]	[189,202,162]	1	hSpCas9	negative selection	1442774
52569885	52569908	12	+	26627737	HeLa	viability after 8 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.4019578244256288	[330]	[105,31,182]	-4	hSpCas9	negative selection	1442775
52571424	52571447	12	-	26627737	HeLa	viability after 8 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.6448905186453067	[912]	[369,211,208]	-6	hSpCas9	negative selection	1442776
52573545	52573568	12	-	26627737	HeLa	viability after 8 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.23191164302512357	[161]	[67,85,29]	-2	hSpCas9	negative selection	1442777
52573657	52573680	12	-	26627737	HeLa	viability after 8 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.3297561747712521	[893]	[342,652,441]	3	hSpCas9	negative selection	1442778
52567016	52567039	12	-	26627737	HeLa	viability after 12 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	-1.9733838260350995	[64]	[1,0,17]	-9	hSpCas9	negative selection	1525088
52567110	52567133	12	+	26627737	HeLa	viability after 12 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.5354005868829468	[384]	[228,199,265]	4	hSpCas9	negative selection	1525089
52569885	52569908	12	+	26627737	HeLa	viability after 12 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.06616497898497889	[330]	[50,104,274]	0	hSpCas9	negative selection	1525090
52571424	52571447	12	-	26627737	HeLa	viability after 12 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.3968498947323058	[912]	[381,177,313]	-4	hSpCas9	negative selection	1525091
52573545	52573568	12	-	26627737	HeLa	viability after 12 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.6656398185205541	[161]	[147,94,77]	5	hSpCas9	negative selection	1525092
52573657	52573680	12	-	26627737	HeLa	viability after 12 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.7696565032379175	[893]	[751,574,571]	6	hSpCas9	negative selection	1525093
52567016	52567039	12	-	26627737	HeLa	viability after 15 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	-3.1962417961031284	[64]	[0,0,6]	-9	hSpCas9	negative selection	1607403
52567110	52567133	12	+	26627737	HeLa	viability after 15 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.4074301152889883	[384]	[142,218,266]	3	hSpCas9	negative selection	1607404
52569885	52569908	12	+	26627737	HeLa	viability after 15 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.12234101071923198	[330]	[117,98,156]	-1	hSpCas9	negative selection	1607405
52571424	52571447	12	-	26627737	HeLa	viability after 15 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-1.455783736139712	[912]	[128,124,153]	-8	hSpCas9	negative selection	1607406
52573545	52573568	12	-	26627737	HeLa	viability after 15 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.1181397456903861	[161]	[64,63,86]	1	hSpCas9	negative selection	1607407
52573657	52573680	12	-	26627737	HeLa	viability after 15 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.1022211037571481	[893]	[400,402,365]	0	hSpCas9	negative selection	1607408
52567016	52567039	12	-	26627737	HeLa	viability after 18 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	-3.081088678257094	[64]	[0,0,6]	-9	hSpCas9	negative selection	1689718
52567110	52567133	12	+	26627737	HeLa	viability after 18 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.4384260109851299	[384]	[108,175,266]	3	hSpCas9	negative selection	1689719
52569885	52569908	12	+	26627737	HeLa	viability after 18 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.11251186423617454	[330]	[79,82,156]	-1	hSpCas9	negative selection	1689720
52571424	52571447	12	-	26627737	HeLa	viability after 18 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-1.461033710853551	[912]	[81,107,153]	-8	hSpCas9	negative selection	1689721
52573545	52573568	12	-	26627737	HeLa	viability after 18 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.1488159511583298	[161]	[44,54,86]	1	hSpCas9	negative selection	1689722
52573657	52573680	12	-	26627737	HeLa	viability after 18 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.08500686258185963	[893]	[262,329,365]	0	hSpCas9	negative selection	1689723
52567016	52567039	12	-	26627737	HCT116	viability after 6 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	6.446760997250641	[1]	[0,41]	9	hSpCas9	negative selection	1772033
52567110	52567133	12	+	26627737	HCT116	viability after 6 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	-0.5452083418457085	[435]	[84,25]	-3	hSpCas9	negative selection	1772034
52569885	52569908	12	+	26627737	HCT116	viability after 6 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	1.6271363957780585	[501]	[246,241]	8	hSpCas9	negative selection	1772035
52571424	52571447	12	-	26627737	HCT116	viability after 6 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.5629972766549967	[1118]	[198,74]	-3	hSpCas9	negative selection	1772036
52573545	52573568	12	-	26627737	HCT116	viability after 6 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	2.3163556970589685	[41]	[48,23]	9	hSpCas9	negative selection	1772037
52573657	52573680	12	-	26627737	HCT116	viability after 6 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.6164238838491263	[1190]	[433,205]	3	hSpCas9	negative selection	1772038
52567016	52567039	12	-	26627737	HCT116	viability after 8 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	2.374102473769402	[3]	[0,13,18]	9	hSpCas9	negative selection	1854348
52567110	52567133	12	+	26627737	HCT116	viability after 8 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.602497779381397	[380]	[285,292,375]	6	hSpCas9	negative selection	1854349
52569885	52569908	12	+	26627737	HCT116	viability after 8 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.2450010661816129	[221]	[226,115,93]	2	hSpCas9	negative selection	1854350
52571424	52571447	12	-	26627737	HCT116	viability after 8 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.2838729897629335	[652]	[311,283,290]	-3	hSpCas9	negative selection	1854351
52573545	52573568	12	-	26627737	HCT116	viability after 8 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.6212463194090441	[96]	[23,40,38]	-6	hSpCas9	negative selection	1854352
52573657	52573680	12	-	26627737	HCT116	viability after 8 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.1979510468973822	[850]	[524,514,572]	2	hSpCas9	negative selection	1854353
52567016	52567039	12	-	26627737	HCT116	viability after 9 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	2.2603210645080436	[1]	[1,2]	9	hSpCas9	negative selection	1936663
52567110	52567133	12	+	26627737	HCT116	viability after 9 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.840241457177554	[435]	[375,75]	6	hSpCas9	negative selection	1936664
52569885	52569908	12	+	26627737	HCT116	viability after 9 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.7561534418206084	[501]	[255,202]	5	hSpCas9	negative selection	1936665
52571424	52571447	12	-	26627737	HCT116	viability after 9 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.10928409687015872	[1118]	[347,301]	0	hSpCas9	negative selection	1936666
52573545	52573568	12	-	26627737	HCT116	viability after 9 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	1.902201993981849	[41]	[56,29]	9	hSpCas9	negative selection	1936667
52573657	52573680	12	-	26627737	HCT116	viability after 9 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.08641108677524745	[1190]	[526,187]	0	hSpCas9	negative selection	1936668
52567016	52567039	12	-	26627737	HCT116	viability after 12 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	4.328831250713657	[3]	[9,18,99]	9	hSpCas9	negative selection	2018978
52567110	52567133	12	+	26627737	HCT116	viability after 12 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.24381995957728314	[380]	[249,189,268]	2	hSpCas9	negative selection	2018979
52569885	52569908	12	+	26627737	HCT116	viability after 12 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.15129302560258323	[221]	[183,132,66]	1	hSpCas9	negative selection	2018980
52571424	52571447	12	-	26627737	HCT116	viability after 12 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.051574374765663844	[652]	[341,355,294]	0	hSpCas9	negative selection	2018981
52573545	52573568	12	-	26627737	HCT116	viability after 12 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.094110848093937	[96]	[31,61,50]	-1	hSpCas9	negative selection	2018982
52573657	52573680	12	-	26627737	HCT116	viability after 12 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.07158445317542705	[850]	[476,374,554]	0	hSpCas9	negative selection	2018983
52567016	52567039	12	-	26627737	HCT116	viability after 15 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	2.9441887362900108	[3]	[25,5,21]	9	hSpCas9	negative selection	2101293
52567110	52567133	12	+	26627737	HCT116	viability after 15 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.37683560766954066	[380]	[375,241,245]	3	hSpCas9	negative selection	2101294
52569885	52569908	12	+	26627737	HCT116	viability after 15 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.149857341961669	[221]	[158,85,180]	1	hSpCas9	negative selection	2101295
52571424	52571447	12	-	26627737	HCT116	viability after 15 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.33774455562057215	[652]	[366,336,195]	-4	hSpCas9	negative selection	2101296
52573545	52573568	12	-	26627737	HCT116	viability after 15 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.10304024819498792	[96]	[54,71,51]	1	hSpCas9	negative selection	2101297
52573657	52573680	12	-	26627737	HCT116	viability after 15 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.13951368917233453	[850]	[736,511,391]	1	hSpCas9	negative selection	2101298
52567016	52567039	12	-	26627737	HCT116	viability after 18 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	3.0645749068071355	[3]	[0,26,19]	9	hSpCas9	negative selection	2183608
52567110	52567133	12	+	26627737	HCT116	viability after 18 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.6031171175377843	[380]	[263,357,208]	5	hSpCas9	negative selection	2183609
52569885	52569908	12	+	26627737	HCT116	viability after 18 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.07617924986245128	[221]	[131,92,79]	0	hSpCas9	negative selection	2183610
52571424	52571447	12	-	26627737	HCT116	viability after 18 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.07517336165659061	[652]	[473,297,222]	0	hSpCas9	negative selection	2183611
52573545	52573568	12	-	26627737	HCT116	viability after 18 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.8792931222227154	[96]	[10,26,38]	-7	hSpCas9	negative selection	2183612
52573657	52573680	12	-	26627737	HCT116	viability after 18 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.3457950266607852	[850]	[576,453,542]	3	hSpCas9	negative selection	2183613
52572623	52572646	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACCAGGTTCTAGAAACCAAGTGG	KRT74	ENSG00000170484	0.44877326533647616	[2,2]	[3,2]	8	hSpCas9	positive selection	2998256
52573464	52573487	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGACAAACATGCAGGCCCCAGGG	KRT74	ENSG00000170484	0.19258640362279467	[4,4]	[4,3]	4	hSpCas9	positive selection	2998257
52573372	52573395	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.29725790582374906	[3,2]	[2,3]	6	hSpCas9	positive selection	2998258
52573446	52573469	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTGTCTGTGTGCCCACCTGGGGG	KRT74	ENSG00000170484	-0.23195500203807307	[4,4]	[4,1]	-3	hSpCas9	positive selection	2998259
52572623	52572646	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACCAGGTTCTAGAAACCAAGTGG	KRT74	ENSG00000170484	-0.5459699980862444	[2,2]	[1,0]	-7	hSpCas9	positive selection	3066114
52573464	52573487	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGACAAACATGCAGGCCCCAGGG	KRT74	ENSG00000170484	0.33065419801243706	[4,4]	[4,2]	6	hSpCas9	positive selection	3066115
52573372	52573395	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.02097439088526338	[3,3]	[2,2]	0	hSpCas9	positive selection	3066116
52573446	52573469	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTGTCTGTGTGCCCACCTGGGGG	KRT74	ENSG00000170484	-0.18669544425877138	[4,4]	[2,2]	-3	hSpCas9	positive selection	3066117
52571964	52571987		+	24336571	A375	resistance to PLX after 7 days	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.1511626098451309	[12,12]	[13,13]	5	hSpCas9	positive selection	3123821
52572640	52572663		-	24336571	A375	resistance to PLX after 7 days	CTTCCTAGAGCAGCAGAACCAGG	KRT74	ENSG00000170484	0.24585974620489254	[10,11]	[13,12]	7	hSpCas9	positive selection	3123822
52572472	52572495		-	24336571	A375	resistance to PLX after 7 days	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.031461879526438086	[15,10]	[12,14]	1	hSpCas9	positive selection	3123823
52571964	52571987		+	24336571	A375	resistance to PLX after 14 days	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	1.2166829543669881	[14,13]	[15,15]	8	hSpCas9	positive selection	3181614
52572640	52572663		-	24336571	A375	resistance to PLX after 14 days	CTTCCTAGAGCAGCAGAACCAGG	KRT74	ENSG00000170484	0.6725324162856612	[10,10]	[8,6]	6	hSpCas9	positive selection	3181615
52572472	52572495		-	24336571	A375	resistance to PLX after 14 days	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.19889475781615226	[12,17]	[6,4]	-2	hSpCas9	positive selection	3181616
52571964	52571987		+	24336571	A375	viability after 7 days	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.11118835648645486	[12]	[12,12]	1	hSpCas9	negative selection	3239407
52572640	52572663		-	24336571	A375	viability after 7 days	CTTCCTAGAGCAGCAGAACCAGG	KRT74	ENSG00000170484	0.46390044878959286	[8]	[10,11]	7	hSpCas9	negative selection	3239408
52572472	52572495		-	24336571	A375	viability after 7 days	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.13072284148401334	[12]	[15,10]	2	hSpCas9	negative selection	3239409
52571964	52571987		+	24336571	A375	viability after 14 days	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.32893232206877987	[12]	[14,13]	4	hSpCas9	negative selection	3297200
52572640	52572663		-	24336571	A375	viability after 14 days	CTTCCTAGAGCAGCAGAACCAGG	KRT74	ENSG00000170484	0.43289877037615626	[8]	[10,10]	5	hSpCas9	negative selection	3297201
52572472	52572495		-	24336571	A375	viability after 14 days	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.2964456448305448	[12]	[12,17]	4	hSpCas9	negative selection	3297202
52570713	52570736	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-1.7055697938914256	[498,498]	[0,0]	-9	hSpCas9	positive selection	3376347
52571983	52572006	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.6279695913662254	[98,98]	[0,0]	3	hSpCas9	positive selection	3376348
52572472	52572495	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.5024387092823666	[107,107]	[0,0]	2	hSpCas9	positive selection	3376349
52572623	52572646	12	-	26780180	HT29	viability (Avana library 4 designs)	ACCAGGTTCTAGAAACCAAGTGG	KRT74	ENSG00000170484	0.942463479780918	[]	[]	3	hSpCas9	negative selection	3435713
52573463	52573486	12	+	26780180	HT29	viability (Avana library 4 designs)	AGACAAACATGCAGGCCCCAGGG	KRT74	ENSG00000170484	-0.187491526408873	[]	[]	-3	hSpCas9	negative selection	3435714
52573372	52573395	12	-	26780180	HT29	viability (Avana library 4 designs)	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.978387637761645	[]	[]	4	hSpCas9	negative selection	3435715
52573446	52573469	12	-	26780180	HT29	viability (Avana library 4 designs)	TTGTCTGTGTGCCCACCTGGGGG	KRT74	ENSG00000170484	0.774804529112071	[]	[]	3	hSpCas9	negative selection	3435716
52573372	52573395	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	3.12185424940013	[]	[]	5	hSpCas9	negative selection	3523413
52572623	52572646	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	ACCAGGTTCTAGAAACCAAGTGG	KRT74	ENSG00000170484	0.503438947800533	[]	[]	0	hSpCas9	negative selection	3523414
52573463	52573486	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGACAAACATGCAGGCCCCAGGG	KRT74	ENSG00000170484	3.991704683206	[]	[]	6	hSpCas9	negative selection	3523415
52573446	52573469	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGTCTGTGTGCCCACCTGGGGG	KRT74	ENSG00000170484	1.84775416407155	[]	[]	2	hSpCas9	negative selection	3523416
52573657	52573680	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	2.26501782675294	[]	[]	3	hSpCas9	negative selection	3523417
52572478	52572501	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTCGGAGCTGAGAAGCATGAGGG	KRT74	ENSG00000170484	3.95833700170164	[]	[]	6	hSpCas9	negative selection	3523418
52573372	52573395	12	-	26780180	A375	viability (Avana lentiGuide)	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	1.16393901661434	[]	[]	1	hSpCas9	negative selection	3632072
52572623	52572646	12	-	26780180	A375	viability (Avana lentiGuide)	ACCAGGTTCTAGAAACCAAGTGG	KRT74	ENSG00000170484	9.8230975391871	[]	[]	6	hSpCas9	negative selection	3632073
52573463	52573486	12	+	26780180	A375	viability (Avana lentiGuide)	AGACAAACATGCAGGCCCCAGGG	KRT74	ENSG00000170484	-1.8657082597618	[]	[]	-3	hSpCas9	negative selection	3632074
52573446	52573469	12	-	26780180	A375	viability (Avana lentiGuide)	TTGTCTGTGTGCCCACCTGGGGG	KRT74	ENSG00000170484	0.484551698274535	[]	[]	0	hSpCas9	negative selection	3632075
52573657	52573680	12	-	26780180	A375	viability (Avana lentiGuide)	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	1.80135357678418	[]	[]	2	hSpCas9	negative selection	3632076
52572478	52572501	12	-	26780180	A375	viability (Avana lentiGuide)	CTCGGAGCTGAGAAGCATGAGGG	KRT74	ENSG00000170484	0.813420023339548	[]	[]	1	hSpCas9	negative selection	3632077
52573372	52573395	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.10295773841589395	[4]	[5,4]	2	hSpCas9	positive selection	3740731
52572623	52572646	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACCAGGTTCTAGAAACCAAGTGG	KRT74	ENSG00000170484	-0.06612575441334899	[4]	[4,3]	-1	hSpCas9	positive selection	3740732
52573463	52573486	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACAAACATGCAGGCCCCAGGG	KRT74	ENSG00000170484	0.15063424672584283	[5]	[6,5]	4	hSpCas9	positive selection	3740733
52573446	52573469	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGTCTGTGTGCCCACCTGGGGG	KRT74	ENSG00000170484	0.2660400856705414	[5]	[6,6]	7	hSpCas9	positive selection	3740734
52573657	52573680	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.0878288487460035	[5]	[5,4]	2	hSpCas9	positive selection	3740735
52572478	52572501	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCGGAGCTGAGAAGCATGAGGG	KRT74	ENSG00000170484	0.14877366698789984	[5]	[5,5]	4	hSpCas9	positive selection	3740736
52573372	52573395	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.18126660523522614	[5]	[4,5]	4	hSpCas9	positive selection	3849338
52572623	52572646	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACCAGGTTCTAGAAACCAAGTGG	KRT74	ENSG00000170484	-0.7897844762858113	[4]	[2,1]	-7	hSpCas9	positive selection	3849339
52573463	52573486	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACAAACATGCAGGCCCCAGGG	KRT74	ENSG00000170484	-0.003141539095011886	[6]	[5,4]	0	hSpCas9	positive selection	3849340
52573446	52573469	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGTCTGTGTGCCCACCTGGGGG	KRT74	ENSG00000170484	0.3356505228787125	[5]	[5,6]	8	hSpCas9	positive selection	3849341
52573657	52573680	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.10831934938842522	[5]	[4,4]	2	hSpCas9	positive selection	3849342
52572478	52572501	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCGGAGCTGAGAAGCATGAGGG	KRT74	ENSG00000170484	0.03804120727899275	[5]	[3,5]	0	hSpCas9	positive selection	3849343
52571427	52571450	12	-	26780180	A375	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	1.18025346589573	[]	[]	6	hSpCas9	negative selection	3955417
52571964	52571987	12	+	26780180	A375	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	1.38139775506265	[]	[]	7	hSpCas9	negative selection	3955418
52570713	52570736	12	+	26780180	A375	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.470851212423437	[]	[]	1	hSpCas9	negative selection	3955419
52571983	52572006	12	-	26780180	A375	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	1.21249884723057	[]	[]	6	hSpCas9	negative selection	3955420
52572472	52572495	12	-	26780180	A375	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	1.65590737341656	[]	[]	8	hSpCas9	negative selection	3955421
52571392	52571415	12	+	26780180	A375	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	1.01285205558863	[]	[]	5	hSpCas9	negative selection	3955422
52571427	52571450	12	-	26780180	HT29	viability (GeCKOv2 library)	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.890876536041032	[]	[]	4	hSpCas9	negative selection	4063383
52571964	52571987	12	+	26780180	HT29	viability (GeCKOv2 library)	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	1.09317635041531	[]	[]	5	hSpCas9	negative selection	4063384
52570713	52570736	12	+	26780180	HT29	viability (GeCKOv2 library)	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.269901121812755	[]	[]	0	hSpCas9	negative selection	4063385
52571983	52572006	12	-	26780180	HT29	viability (GeCKOv2 library)	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	1.44937668606333	[]	[]	7	hSpCas9	negative selection	4063386
52572472	52572495	12	-	26780180	HT29	viability (GeCKOv2 library)	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	1.82945999024908	[]	[]	8	hSpCas9	negative selection	4063387
52571392	52571415	12	+	26780180	HT29	viability (GeCKOv2 library)	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.769937865309789	[]	[]	3	hSpCas9	negative selection	4063388
52571964	52571987	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.4355772267442997	[3]	[2,3]	8	hSpCas9	positive selection	4147791
52572640	52572663	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CTTCCTAGAGCAGCAGAACCAGG	KRT74	ENSG00000170484	-0.14218509091623646	[3]	[0,2]	-3	hSpCas9	positive selection	4147792
52572472	52572495	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.2269792384119358	[4]	[1,2]	-5	hSpCas9	positive selection	4147793
52571964	52571987	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.9814223173121868	[3]	[0,0,5,3]	7	hSpCas9	positive selection	4211813
52572640	52572663	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CTTCCTAGAGCAGCAGAACCAGG	KRT74	ENSG00000170484	-0.7995710749479206	[3]	[0,0,0,0]	-9	hSpCas9	positive selection	4211814
52572472	52572495	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.8063131902413181	[3]	[0,0,1,0]	-9	hSpCas9	positive selection	4211815
52571964	52571987	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.9689312110600456	[2]	[0,0]	-9	hSpCas9	positive selection	4279209
52571427	52571450	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.37768932929301313	[3]	[3,0]	-7	hSpCas9	positive selection	4279210
52571392	52571415	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	-0.09279227998889102	[3]	[3,1]	-2	hSpCas9	positive selection	4279211
52570713	52570736	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.3995276968291073	[4]	[4,4]	7	hSpCas9	positive selection	4343464
52571983	52572006	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.44986297631412925	[2]	[0,0]	-7	hSpCas9	positive selection	4343465
52572472	52572495	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.4274845679071456	[2]	[2,0]	-7	hSpCas9	positive selection	4343466
52570714	52570736	12	+	27760321	OCIAML3	viability	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	1.0420588075125883	[316,287]	[386,616]	9	hSpCas9	negative selection	4413216
52571424	52571446	12	-	27760321	OCIAML3	viability	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.3135806141184928	[461,385]	[263,267]	-3	hSpCas9	negative selection	4413217
52571965	52571987	12	+	27760321	OCIAML3	viability	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.4021306795164865	[1125,1149]	[1068,1326]	5	hSpCas9	negative selection	4413218
52573463	52573485	12	+	27760321	OCIAML3	viability	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.4533628743401263	[621,555]	[513,780]	5	hSpCas9	negative selection	4413219
52573607	52573629	12	-	27760321	OCIAML3	viability	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	-0.48043887521480155	[436,388]	[228,233]	-5	hSpCas9	negative selection	4413220
52570714	52570736	12	+	27760321	OCIAML2	viability	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.32452446394578627	[316,287]	[187,461]	4	hSpCas9	negative selection	4496679
52571424	52571446	12	-	27760321	OCIAML2	viability	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.028261319992415223	[461,385]	[274,444]	0	hSpCas9	negative selection	4496680
52571965	52571987	12	+	27760321	OCIAML2	viability	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.19127523477468622	[1125,1149]	[985,1146]	2	hSpCas9	negative selection	4496681
52573463	52573485	12	+	27760321	OCIAML2	viability	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.4190675004711099	[621,555]	[558,737]	6	hSpCas9	negative selection	4496682
52573607	52573629	12	-	27760321	OCIAML2	viability	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	-0.14468354552774892	[436,388]	[334,257]	-2	hSpCas9	negative selection	4496683
52570714	52570736	12	+	27760321	MV411	viability	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	2.2687864892931175	[316,287]	[1416,276]	9	hSpCas9	negative selection	4580142
52571424	52571446	12	-	27760321	MV411	viability	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.11743643530608189	[461,385]	[169,500]	0	hSpCas9	negative selection	4580143
52571965	52571987	12	+	27760321	MV411	viability	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.5313650907664036	[1125,1149]	[937,1317]	4	hSpCas9	negative selection	4580144
52573463	52573485	12	+	27760321	MV411	viability	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	1.0564264868711397	[621,555]	[694,975]	7	hSpCas9	negative selection	4580145
52573607	52573629	12	-	27760321	MV411	viability	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	-0.23814501129477994	[436,388]	[139,366]	-2	hSpCas9	negative selection	4580146
52570714	52570736	12	+	27760321	HL60	viability	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.22127322733064247	[316,287]	[316,256]	2	hSpCas9	negative selection	4663605
52571424	52571446	12	-	27760321	HL60	viability	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.33089579853874945	[461,385]	[412,455]	4	hSpCas9	negative selection	4663606
52571965	52571987	12	+	27760321	HL60	viability	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.1610207069086249	[1125,1149]	[714,961]	-2	hSpCas9	negative selection	4663607
52573463	52573485	12	+	27760321	HL60	viability	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.4532699764107026	[621,555]	[653,661]	5	hSpCas9	negative selection	4663608
52573607	52573629	12	-	27760321	HL60	viability	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	0.9607533770196309	[436,388]	[693,614]	8	hSpCas9	negative selection	4663609
52570714	52570736	12	+	27760321	HT1080	viability	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.9286030544410087	[287,224]	[278,101]	5	hSpCas9	negative selection	4747068
52571424	52571446	12	-	27760321	HT1080	viability	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	1.213223704283354	[385,300]	[290,345]	6	hSpCas9	negative selection	4747069
52571965	52571987	12	+	27760321	HT1080	viability	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.3112608201542266	[1149,897]	[414,605]	1	hSpCas9	negative selection	4747070
52573463	52573485	12	+	27760321	HT1080	viability	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	-0.8653849672424005	[555,433]	[28,194]	-4	hSpCas9	negative selection	4747071
52573607	52573629	12	-	27760321	HT1080	viability	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	0.6454100098876259	[388,303]	[224,205]	3	hSpCas9	negative selection	4747072
52570714	52570736	12	+	27760321	HT29	viability after 7 days	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.08732132264993103	[287,224]	[295,399,346]	1	hSpCas9	negative selection	4830531
52571424	52571446	12	-	27760321	HT29	viability after 7 days	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.22469671797994417	[385,300]	[361,474,682]	3	hSpCas9	negative selection	4830532
52571965	52571987	12	+	27760321	HT29	viability after 7 days	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-1.088481011901131	[1149,897]	[644,588,625]	-8	hSpCas9	negative selection	4830533
52573463	52573485	12	+	27760321	HT29	viability after 7 days	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.610641065772014	[555,433]	[1127,1082,732]	8	hSpCas9	negative selection	4830534
52573607	52573629	12	-	27760321	HT29	viability after 7 days	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	-0.14247999503990447	[388,303]	[513,369,343]	-2	hSpCas9	negative selection	4830535
52570714	52570736	12	+	27760321	HT29	viability after 25 days	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.2259461803497611	[287,224]	[127,411,519]	2	hSpCas9	negative selection	4913994
52571424	52571446	12	-	27760321	HT29	viability after 25 days	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.7231022080454479	[385,300]	[676,642,617]	7	hSpCas9	negative selection	4913995
52571965	52571987	12	+	27760321	HT29	viability after 25 days	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.9751609142908058	[1149,897]	[587,657,532]	-6	hSpCas9	negative selection	4913996
52573463	52573485	12	+	27760321	HT29	viability after 25 days	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.8653062057081122	[555,433]	[1047,1044,991]	8	hSpCas9	negative selection	4913997
52573607	52573629	12	-	27760321	HT29	viability after 25 days	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	0.28706816315332023	[388,303]	[405,639,398]	3	hSpCas9	negative selection	4913998
52570714	52570736	12	+	27760321	HT29	viability after 22 days	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.2434927821856213	[287,224]	[389,324,336]	2	hSpCas9	negative selection	4997457
52571424	52571446	12	-	27760321	HT29	viability after 22 days	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.47786353607095045	[385,300]	[477,632,549]	5	hSpCas9	negative selection	4997458
52571965	52571987	12	+	27760321	HT29	viability after 22 days	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-1.0372794043832019	[1149,897]	[557,693,477]	-6	hSpCas9	negative selection	4997459
52573463	52573485	12	+	27760321	HT29	viability after 22 days	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.7380192825520913	[555,433]	[1330,893,624]	8	hSpCas9	negative selection	4997460
52573607	52573629	12	-	27760321	HT29	viability after 22 days	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	-0.03558759707547702	[388,303]	[452,413,302]	0	hSpCas9	negative selection	4997461
52570714	52570736	12	+	27760321	HT29	viability after 19 days	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.4898681513984011	[287,224]	[549,257,440]	5	hSpCas9	negative selection	5080920
52571424	52571446	12	-	27760321	HT29	viability after 19 days	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.5597948741193273	[385,300]	[598,617,523]	5	hSpCas9	negative selection	5080921
52571965	52571987	12	+	27760321	HT29	viability after 19 days	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.539536075488454	[1149,897]	[891,761,772]	-5	hSpCas9	negative selection	5080922
52573463	52573485	12	+	27760321	HT29	viability after 19 days	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.7058462513634716	[555,433]	[823,979,953]	7	hSpCas9	negative selection	5080923
52573607	52573629	12	-	27760321	HT29	viability after 19 days	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	0.10320496153752051	[388,303]	[659,366,279]	0	hSpCas9	negative selection	5080924
52570714	52570736	12	+	27760321	HT29	viability after 16 days	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.38460979342339374	[287,224]	[229,461,415]	4	hSpCas9	negative selection	5164383
52571424	52571446	12	-	27760321	HT29	viability after 16 days	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.9114549699479609	[385,300]	[677,650,836]	9	hSpCas9	negative selection	5164384
52571965	52571987	12	+	27760321	HT29	viability after 16 days	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.8254056232404455	[1149,897]	[748,500,702]	-6	hSpCas9	negative selection	5164385
52573463	52573485	12	+	27760321	HT29	viability after 16 days	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.3434361152091177	[555,433]	[834,678,606]	4	hSpCas9	negative selection	5164386
52573607	52573629	12	-	27760321	HT29	viability after 16 days	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	0.365041878461065	[388,303]	[345,667,464]	4	hSpCas9	negative selection	5164387
52570714	52570736	12	+	27760321	HT29	viability after 13 days	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.327362513108879	[287,224]	[464,419,242]	4	hSpCas9	negative selection	5247846
52571424	52571446	12	-	27760321	HT29	viability after 13 days	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.6848189741876773	[385,300]	[734,710,484]	8	hSpCas9	negative selection	5247847
52571965	52571987	12	+	27760321	HT29	viability after 13 days	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.8435810815644543	[1149,897]	[806,642,542]	-7	hSpCas9	negative selection	5247848
52573463	52573485	12	+	27760321	HT29	viability after 13 days	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.43587165562786206	[555,433]	[967,723,645]	5	hSpCas9	negative selection	5247849
52573607	52573629	12	-	27760321	HT29	viability after 13 days	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	0.3641747200968186	[388,303]	[575,456,518]	4	hSpCas9	negative selection	5247850
52570714	52570736	12	+	27760321	HT29	viability after 10 days	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.02009276658926923	[287,224]	[362,244,336]	0	hSpCas9	negative selection	5331309
52571424	52571446	12	-	27760321	HT29	viability after 10 days	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.6020400955301424	[385,300]	[507,980,476]	7	hSpCas9	negative selection	5331310
52571965	52571987	12	+	27760321	HT29	viability after 10 days	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.8672100655327203	[1149,897]	[831,789,487]	-7	hSpCas9	negative selection	5331311
52573463	52573485	12	+	27760321	HT29	viability after 10 days	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.4641437934210902	[555,433]	[991,837,729]	6	hSpCas9	negative selection	5331312
52573607	52573629	12	-	27760321	HT29	viability after 10 days	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	0.2963037590767315	[388,303]	[478,437,670]	4	hSpCas9	negative selection	5331313
52570714	52570736	12	+	27760321	MOLM13	viability	GATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.5936816206808513	[316,287]	[231,278]	4	hSpCas9	negative selection	5414772
52571424	52571446	12	-	27760321	MOLM13	viability	GCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.8057711238773672	[461,385]	[584,272]	5	hSpCas9	negative selection	5414773
52571965	52571987	12	+	27760321	MOLM13	viability	ATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.5561003766179797	[1125,1149]	[1143,780]	4	hSpCas9	negative selection	5414774
52573463	52573485	12	+	27760321	MOLM13	viability	AGACAAACATGCAGGCCCCAGG	KRT74	ENSG00000170484	0.44459263273702093	[621,555]	[462,441]	3	hSpCas9	negative selection	5414775
52573607	52573629	12	-	27760321	MOLM13	viability	CTATAGCCTTGGAGGGAATCGG	KRT74	ENSG00000170484	-0.4545675798253893	[436,388]	[91,235]	-3	hSpCas9	negative selection	5414776
52573609	52573632	12	+	27661255	K562	viability	GATTCCCTCCAAGGCTATAGAGG	KRT74	ENSG00000170484	0.11097490899542128	[537,605]	[547,444]	4	dCas9-KRAB	negative selection	5489350
52573757	52573780	12	+	27661255	K562	viability	GATGTTCAGTTGCCGACTCATGG	KRT74	ENSG00000170484	0.050383579762665054	[2794,3048]	[2524,2317]	1	dCas9-KRAB	negative selection	5489351
52573557	52573580	12	-	27661255	K562	viability	GGCGTTCGGGCTGGAGGTTACGG	KRT74	ENSG00000170484	0.10815470939274618	[634,525]	[575,437]	4	dCas9-KRAB	negative selection	5489352
52573613	52573636	12	-	27661255	K562	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	0.09287205975243118	[1014,1182]	[944,923]	3	dCas9-KRAB	negative selection	5489353
52571964	52571987	12	+	27260156	BXPC3	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.23954359530195468	[235]	[144,210,241,248]	-5	hSpCas9	negative selection	5551669
52571427	52571450	12	-	27260156	BXPC3	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.05057274484495711	[559]	[587,619,463,767]	1	hSpCas9	negative selection	5551670
52571392	52571415	12	+	27260156	BXPC3	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.22182454437803412	[661]	[643,802,796,1023]	5	hSpCas9	negative selection	5551671
52570713	52570736	12	+	27260156	BXPC3	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.0645535706464706	[1249]	[994,1286,1250,1515]	-1	hSpCas9	negative selection	5615924
52571983	52572006	12	-	27260156	BXPC3	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.0024139738926238774	[274]	[299,278,262,304]	0	hSpCas9	negative selection	5615925
52572472	52572495	12	-	27260156	BXPC3	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.07308551442991607	[394]	[359,338,393,493]	-2	hSpCas9	negative selection	5615926
52571964	52571987	12	+	27260156	A673	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.1152978955205286	[235]	[369,307,219,338]	2	hSpCas9	negative selection	5672920
52571427	52571450	12	-	27260156	A673	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.08274201259087582	[559]	[614,634,650,634]	-2	hSpCas9	negative selection	5672921
52571392	52571415	12	+	27260156	A673	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.2543688150619873	[661]	[1039,790,991,983]	6	hSpCas9	negative selection	5672922
52570713	52570736	12	+	27260156	A673	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.05748530898458748	[1249]	[1853,1530,1496,1387]	1	hSpCas9	negative selection	5737175
52571983	52572006	12	-	27260156	A673	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.028204899232076586	[274]	[417,288,313,335]	0	hSpCas9	negative selection	5737176
52572472	52572495	12	-	27260156	A673	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.1391143235117328	[394]	[452,425,381,465]	-3	hSpCas9	negative selection	5737177
52571964	52571987	12	+	27260156	A375	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.08843448333020765	[235]	[409,273,299,196]	1	hSpCas9	negative selection	5794171
52571427	52571450	12	-	27260156	A375	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.2369679541014	[559]	[571,625,457,569]	-3	hSpCas9	negative selection	5794172
52571392	52571415	12	+	27260156	A375	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.1462039893789575	[661]	[790,1006,786,854]	2	hSpCas9	negative selection	5794173
52570713	52570736	12	+	27260156	A375	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.19013050169008827	[1249]	[1837,1800,1757,1320]	2	hSpCas9	negative selection	5858426
52571983	52572006	12	-	27260156	A375	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.24273660212078796	[274]	[413,743,247,186]	3	hSpCas9	negative selection	5858427
52572472	52572495	12	-	27260156	A375	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.6728144539359828	[394]	[289,415,177,289]	-7	hSpCas9	negative selection	5858428
52571964	52571987	12	+	27260156	COLO741	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.15318002980611067	[235]	[432,268,312]	3	hSpCas9	negative selection	5915422
52571427	52571450	12	-	27260156	COLO741	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.3557277900538517	[559]	[757,922,1040]	7	hSpCas9	negative selection	5915423
52571392	52571415	12	+	27260156	COLO741	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.4812895265972089	[661]	[1179,946,1395]	8	hSpCas9	negative selection	5915424
52570713	52570736	12	+	27260156	COLO741	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.06919664584049601	[1249]	[1842,1473,1290]	-1	hSpCas9	negative selection	5979677
52571983	52572006	12	-	27260156	COLO741	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.22126927993009027	[274]	[318,471,427]	5	hSpCas9	negative selection	5979678
52572472	52572495	12	-	27260156	COLO741	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.587570197856637	[394]	[299,397,307]	-8	hSpCas9	negative selection	5979679
52571964	52571987	12	+	27260156	CAL120	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.23006673419941315	[235]	[204,387,152]	-3	hSpCas9	negative selection	6036673
52571427	52571450	12	-	27260156	CAL120	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.9753498865377384	[559]	[392,379,296]	-8	hSpCas9	negative selection	6036674
52571392	52571415	12	+	27260156	CAL120	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.4341285840207125	[661]	[1193,1336,824]	6	hSpCas9	negative selection	6036675
52570713	52570736	12	+	27260156	CAL120	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.31361022031719155	[1249]	[1706,1045,1072]	-4	hSpCas9	negative selection	6100928
52571983	52572006	12	-	27260156	CAL120	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.13074238265768445	[274]	[345,424,348]	2	hSpCas9	negative selection	6100929
52572472	52572495	12	-	27260156	CAL120	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.1918218405658342	[394]	[763,358,590]	3	hSpCas9	negative selection	6100930
52571964	52571987	12	+	27260156	CADOES1	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.4432731469782094	[235]	[398,253,303,233]	7	hSpCas9	negative selection	6157924
52571427	52571450	12	-	27260156	CADOES1	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.030945264716496917	[559]	[559,529,465,481]	0	hSpCas9	negative selection	6157925
52571392	52571415	12	+	27260156	CADOES1	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.32518909958268005	[661]	[796,798,627,864]	5	hSpCas9	negative selection	6157926
52570713	52570736	12	+	27260156	CADOES1	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.08755155251410596	[1249]	[1117,1336,1142,1347]	1	hSpCas9	negative selection	6222179
52571983	52572006	12	-	27260156	CADOES1	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.17487671564479024	[274]	[307,271,306,266]	3	hSpCas9	negative selection	6222180
52572472	52572495	12	-	27260156	CADOES1	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.040275763051929314	[394]	[301,429,436,340]	0	hSpCas9	negative selection	6222181
52571964	52571987	12	+	27260156	EWS502	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.3236593039146579	[235]	[206,311,330,420]	5	hSpCas9	negative selection	6279175
52571427	52571450	12	-	27260156	EWS502	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.09360316754849937	[559]	[580,445,752,436]	-2	hSpCas9	negative selection	6279176
52571392	52571415	12	+	27260156	EWS502	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.4377600761290039	[661]	[959,962,1001,862]	7	hSpCas9	negative selection	6279177
52570713	52570736	12	+	27260156	EWS502	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.1577954415282854	[1249]	[1196,1551,1668,1520]	2	hSpCas9	negative selection	6343430
52571983	52572006	12	-	27260156	EWS502	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.3677555058435382	[274]	[297,462,446,294]	6	hSpCas9	negative selection	6343431
52572472	52572495	12	-	27260156	EWS502	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.28157577771950976	[394]	[156,506,384,342]	-5	hSpCas9	negative selection	6343432
52571964	52571987	12	+	27260156	EW8	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.13530489738474216	[235]	[298,249,161,146]	2	hSpCas9	negative selection	6400426
52571427	52571450	12	-	27260156	EW8	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.370230823037737	[559]	[331,357,244,483]	-6	hSpCas9	negative selection	6400427
52571392	52571415	12	+	27260156	EW8	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.22166423880910047	[661]	[905,671,520,450]	4	hSpCas9	negative selection	6400428
52570713	52570736	12	+	27260156	EW8	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.01931256678642823	[1249]	[1225,986,943,872]	0	hSpCas9	negative selection	6464681
52571983	52572006	12	-	27260156	EW8	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.1289953053253402	[274]	[199,248,170,199]	-2	hSpCas9	negative selection	6464682
52572472	52572495	12	-	27260156	EW8	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.12554908659180908	[394]	[402,294,174,331]	-2	hSpCas9	negative selection	6464683
52571964	52571987	12	+	27260156	CORL105	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.33189467900224534	[235]	[457,353,353,229]	6	hSpCas9	negative selection	6521677
52571427	52571450	12	-	27260156	CORL105	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.060446828737511976	[559]	[815,511,637,558]	-1	hSpCas9	negative selection	6521678
52571392	52571415	12	+	27260156	CORL105	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.26407628002653427	[661]	[755,881,1090,1012]	5	hSpCas9	negative selection	6521679
52570713	52570736	12	+	27260156	CORL105	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.010141515784432453	[1249]	[1214,1379,1853,1418]	0	hSpCas9	negative selection	6585932
52571983	52572006	12	-	27260156	CORL105	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.10123723126466788	[274]	[332,222,534,321]	2	hSpCas9	negative selection	6585933
52572472	52572495	12	-	27260156	CORL105	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.07337748983111592	[394]	[469,574,573,338]	1	hSpCas9	negative selection	6585934
52571964	52571987	12	+	27260156	HS294T	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.9116716361464833	[235]	[150,165,80,313]	9	hSpCas9	negative selection	6642928
52571427	52571450	12	-	27260156	HS294T	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.0404544662630657	[559]	[193,136,316,194]	0	hSpCas9	negative selection	6642929
52571392	52571415	12	+	27260156	HS294T	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.028262484769457696	[661]	[158,299,255,351]	0	hSpCas9	negative selection	6642930
52570713	52570736	12	+	27260156	HS294T	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.7755100284301053	[1249]	[468,1782,471,535]	8	hSpCas9	negative selection	6707183
52571983	52572006	12	-	27260156	HS294T	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.2553149353096311	[274]	[75,103,165,174]	3	hSpCas9	negative selection	6707184
52572472	52572495	12	-	27260156	HS294T	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.8754080945630722	[394]	[302,135,190,534]	9	hSpCas9	negative selection	6707185
52571964	52571987	12	+	27260156	HCC44	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.1274051863335358	[235]	[277,216,335,347]	2	hSpCas9	negative selection	6764179
52571427	52571450	12	-	27260156	HCC44	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.396294398915801	[559]	[494,291,612,568]	-6	hSpCas9	negative selection	6764180
52571392	52571415	12	+	27260156	HCC44	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.16920374107795988	[661]	[1093,555,1019,786]	2	hSpCas9	negative selection	6764181
52570713	52570736	12	+	27260156	HCC44	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.151706892857574	[1249]	[1861,1213,1944,1395]	2	hSpCas9	negative selection	6828434
52571983	52572006	12	-	27260156	HCC44	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.3934131091954259	[274]	[186,405,456,563]	6	hSpCas9	negative selection	6828435
52572472	52572495	12	-	27260156	HCC44	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.39562968494903555	[394]	[291,383,483,213]	-6	hSpCas9	negative selection	6828436
52571964	52571987	12	+	27260156	G402	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.7501638108153448	[235]	[355,596,643,333]	8	hSpCas9	negative selection	6885430
52571427	52571450	12	-	27260156	G402	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.03666788807595328	[559]	[533,862,683,704]	0	hSpCas9	negative selection	6885431
52571392	52571415	12	+	27260156	G402	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.36115487428272997	[661]	[745,1175,768,1402]	4	hSpCas9	negative selection	6885432
52570713	52570736	12	+	27260156	G402	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.26108358102184726	[1249]	[1786,2068,1557,1894]	3	hSpCas9	negative selection	6949685
52571983	52572006	12	-	27260156	G402	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.6791722660256293	[274]	[942,481,441,344]	8	hSpCas9	negative selection	6949686
52572472	52572495	12	-	27260156	G402	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.2845008358794138	[394]	[391,492,380,323]	-4	hSpCas9	negative selection	6949687
52571964	52571987	12	+	27260156	L33	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.14040891806664213	[235]	[188,97,174,334]	3	hSpCas9	negative selection	7006681
52571427	52571450	12	-	27260156	L33	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.11901974153125405	[559]	[480,221,309,546]	-3	hSpCas9	negative selection	7006682
52571392	52571415	12	+	27260156	L33	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.11985437231155516	[661]	[605,307,429,836]	2	hSpCas9	negative selection	7006683
52570713	52570736	12	+	27260156	L33	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.17676333019088064	[1249]	[1098,418,749,1108]	-4	hSpCas9	negative selection	7070936
52571983	52572006	12	-	27260156	L33	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.05334925051931938	[274]	[268,129,169,284]	1	hSpCas9	negative selection	7070937
52572472	52572495	12	-	27260156	L33	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.3876289117241757	[394]	[356,217,330,653]	7	hSpCas9	negative selection	7070938
52571964	52571987	12	+	27260156	K562	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.06901001829673437	[235]	[219,251,194,141]	-1	hSpCas9	negative selection	7127932
52571427	52571450	12	-	27260156	K562	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.45961021122226076	[559]	[385,463,226,372]	-5	hSpCas9	negative selection	7127933
52571392	52571415	12	+	27260156	K562	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.054775154490575795	[661]	[800,356,685,597]	0	hSpCas9	negative selection	7127934
52570713	52570736	12	+	27260156	K562	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.14836536664355093	[1249]	[1761,1130,1300,806]	1	hSpCas9	negative selection	7192187
52571983	52572006	12	-	27260156	K562	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.10067733046190142	[274]	[346,152,191,344]	1	hSpCas9	negative selection	7192188
52572472	52572495	12	-	27260156	K562	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.4789894715604032	[394]	[95,244,428,224]	-5	hSpCas9	negative selection	7192189
52571964	52571987	12	+	27260156	HT29	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.09587991975834498	[235]	[273,337,212,388]	1	hSpCas9	negative selection	7249183
52571427	52571450	12	-	27260156	HT29	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.14100177884181136	[559]	[762,604,569,545]	-3	hSpCas9	negative selection	7249184
52571392	52571415	12	+	27260156	HT29	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.18020458147033902	[661]	[932,892,1121,716]	3	hSpCas9	negative selection	7249185
52570713	52570736	12	+	27260156	HT29	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.040872996449802024	[1249]	[1657,1605,1664,1349]	0	hSpCas9	negative selection	7313438
52571983	52572006	12	-	27260156	HT29	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.05209460570113977	[274]	[369,308,405,217]	-1	hSpCas9	negative selection	7313439
52572472	52572495	12	-	27260156	HT29	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.015748204829855034	[394]	[399,607,554,390]	0	hSpCas9	negative selection	7313440
52571964	52571987	12	+	27260156	MHHES1	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.3934507024904934	[235]	[366,259,456,307]	7	hSpCas9	negative selection	7370434
52571427	52571450	12	-	27260156	MHHES1	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.1255030594521151	[559]	[555,828,688,311]	-2	hSpCas9	negative selection	7370435
52571392	52571415	12	+	27260156	MHHES1	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.11619663284976467	[661]	[773,841,799,798]	2	hSpCas9	negative selection	7370436
52570713	52570736	12	+	27260156	MHHES1	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.03994369385505658	[1249]	[1743,1616,1418,1108]	0	hSpCas9	negative selection	7434689
52571983	52572006	12	-	27260156	MHHES1	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.0804749653941551	[274]	[368,392,272,287]	1	hSpCas9	negative selection	7434690
52572472	52572495	12	-	27260156	MHHES1	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.0786974434198135	[394]	[444,458,316,608]	1	hSpCas9	negative selection	7434691
52571964	52571987	12	+	27260156	MEWO	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.20765848296476586	[235]	[347,231,202]	4	hSpCas9	negative selection	7491685
52571427	52571450	12	-	27260156	MEWO	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.3481160262499422	[559]	[447,357,435]	-6	hSpCas9	negative selection	7491686
52571392	52571415	12	+	27260156	MEWO	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.11952778549571619	[661]	[789,686,563]	2	hSpCas9	negative selection	7491687
52570713	52570736	12	+	27260156	MEWO	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.09437003599782945	[1249]	[1206,1215,883]	-2	hSpCas9	negative selection	7555940
52571983	52572006	12	-	27260156	MEWO	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.12395555663033375	[274]	[300,284,258]	2	hSpCas9	negative selection	7555941
52572472	52572495	12	-	27260156	MEWO	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.589774423683767	[394]	[309,258,179]	-8	hSpCas9	negative selection	7555942
52571964	52571987	12	+	27260156	LNCAPCLONEFGC	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.059022235390337796	[235]	[173,264,270,185]	0	hSpCas9	negative selection	7612936
52571427	52571450	12	-	27260156	LNCAPCLONEFGC	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.2275323752010055	[559]	[389,415,589,361]	-4	hSpCas9	negative selection	7612937
52571392	52571415	12	+	27260156	LNCAPCLONEFGC	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.2658517981589703	[661]	[708,584,910,715]	4	hSpCas9	negative selection	7612938
52570713	52570736	12	+	27260156	LNCAPCLONEFGC	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.17550707636390928	[1249]	[1266,1123,1441,1315]	2	hSpCas9	negative selection	7677191
52571983	52572006	12	-	27260156	LNCAPCLONEFGC	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.008270839066471969	[274]	[137,289,340,245]	0	hSpCas9	negative selection	7677192
52572472	52572495	12	-	27260156	LNCAPCLONEFGC	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.9816277948227241	[394]	[193,161,189,180]	-8	hSpCas9	negative selection	7677193
52571964	52571987	12	+	27260156	PANC0327	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.5371630298308041	[235]	[155,196,126,91]	-6	hSpCas9	negative selection	7734187
52571427	52571450	12	-	27260156	PANC0327	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.13417742668921046	[559]	[574,458,335,451]	-2	hSpCas9	negative selection	7734188
52571392	52571415	12	+	27260156	PANC0327	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.6174497729570907	[661]	[596,1290,762,881]	8	hSpCas9	negative selection	7734189
52570713	52570736	12	+	27260156	PANC0327	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.12645779360582488	[1249]	[1329,1369,983,1152]	1	hSpCas9	negative selection	7798442
52571983	52572006	12	-	27260156	PANC0327	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.10012089874644936	[274]	[406,245,132,274]	1	hSpCas9	negative selection	7798443
52572472	52572495	12	-	27260156	PANC0327	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.2623442746948304	[394]	[385,288,185,316]	-4	hSpCas9	negative selection	7798444
52571964	52571987	12	+	27260156	NCIH2009	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.10810388443447505	[235]	[349,248,327]	-1	hSpCas9	negative selection	7855438
52571427	52571450	12	-	27260156	NCIH2009	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.28194826236927323	[559]	[972,509,513]	-4	hSpCas9	negative selection	7855439
52571392	52571415	12	+	27260156	NCIH2009	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.008980802270685206	[661]	[1073,865,879]	0	hSpCas9	negative selection	7855440
52570713	52570736	12	+	27260156	NCIH2009	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.2129984497787214	[1249]	[1876,1386,1328]	-3	hSpCas9	negative selection	7919693
52571983	52572006	12	-	27260156	NCIH2009	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.20328515433358918	[274]	[328,259,411]	-3	hSpCas9	negative selection	7919694
52572472	52572495	12	-	27260156	NCIH2009	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.12668070048375407	[394]	[666,478,401]	-2	hSpCas9	negative selection	7919695
52571964	52571987	12	+	27260156	NCIH1373	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.7010454304976104	[235]	[592,390,394,95]	7	hSpCas9	negative selection	7976689
52571427	52571450	12	-	27260156	NCIH1373	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.16782481881454814	[559]	[583,373,797,128]	-2	hSpCas9	negative selection	7976690
52571392	52571415	12	+	27260156	NCIH1373	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	-0.3472576040807215	[661]	[375,532,799,154]	-3	hSpCas9	negative selection	7976691
52570713	52570736	12	+	27260156	NCIH1373	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.7770880949395812	[1249]	[843,851,686,233]	-7	hSpCas9	negative selection	8040944
52571983	52572006	12	-	27260156	NCIH1373	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.3692262031525644	[274]	[427,254,752,39]	3	hSpCas9	negative selection	8040945
52572472	52572495	12	-	27260156	NCIH1373	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-1.059004913601677	[394]	[347,117,225,48]	-8	hSpCas9	negative selection	8040946
52571964	52571987	12	+	27260156	PATU8902	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.5598355867732544	[235]	[716,401,336,516]	6	hSpCas9	negative selection	8097940
52571427	52571450	12	-	27260156	PATU8902	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.24643887818175658	[559]	[1195,1053,656,842]	2	hSpCas9	negative selection	8097941
52571392	52571415	12	+	27260156	PATU8902	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	-0.11863595436722807	[661]	[872,863,761,921]	-1	hSpCas9	negative selection	8097942
52570713	52570736	12	+	27260156	PATU8902	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.7374589575102652	[1249]	[1134,965,1024,1045]	-6	hSpCas9	negative selection	8162195
52571983	52572006	12	-	27260156	PATU8902	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.38928418988970936	[274]	[228,652,138,173]	-4	hSpCas9	negative selection	8162196
52572472	52572495	12	-	27260156	PATU8902	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.35941232801103157	[394]	[537,204,1192,761]	3	hSpCas9	negative selection	8162197
52571964	52571987	12	+	27260156	PANC1	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.4211204313026544	[235]	[196,475,258,203]	6	hSpCas9	negative selection	8219191
52571427	52571450	12	-	27260156	PANC1	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.1724806587529143	[559]	[467,751,400,575]	2	hSpCas9	negative selection	8219192
52571392	52571415	12	+	27260156	PANC1	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.4213740742636505	[661]	[757,642,962,662]	6	hSpCas9	negative selection	8219193
52570713	52570736	12	+	27260156	PANC1	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.2910184254972683	[1249]	[1309,1477,1342,1160]	5	hSpCas9	negative selection	8283446
52571983	52572006	12	-	27260156	PANC1	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.22455455226642795	[274]	[351,273,296,188]	3	hSpCas9	negative selection	8283447
52572472	52572495	12	-	27260156	PANC1	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.1607738581951712	[394]	[405,491,332,312]	2	hSpCas9	negative selection	8283448
52571964	52571987	12	+	27260156	PANC0813	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.32417348715923766	[235]	[361,426,311,290]	5	hSpCas9	negative selection	8340442
52571427	52571450	12	-	27260156	PANC0813	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.12668294645798273	[559]	[690,665,821,691]	2	hSpCas9	negative selection	8340443
52571392	52571415	12	+	27260156	PANC0813	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	-0.045120432982338476	[661]	[772,704,759,775]	0	hSpCas9	negative selection	8340444
52570713	52570736	12	+	27260156	PANC0813	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.20455928666564227	[1249]	[1419,1317,1227,1148]	-3	hSpCas9	negative selection	8404697
52571983	52572006	12	-	27260156	PANC0813	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.19483108652985004	[274]	[304,261,237,322]	-3	hSpCas9	negative selection	8404698
52572472	52572495	12	-	27260156	PANC0813	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.12642135295232992	[394]	[582,571,413,464]	2	hSpCas9	negative selection	8404699
52571964	52571987	12	+	27260156	RDES	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.5348348133186778	[235]	[354,345,528,339]	8	hSpCas9	negative selection	8461693
52571427	52571450	12	-	27260156	RDES	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.4674739207938169	[559]	[370,402,536,585]	-7	hSpCas9	negative selection	8461694
52571392	52571415	12	+	27260156	RDES	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	-0.09112458255475042	[661]	[523,601,727,1095]	-1	hSpCas9	negative selection	8461695
52570713	52570736	12	+	27260156	RDES	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.19394393944055288	[1249]	[1016,1139,1411,1530]	-3	hSpCas9	negative selection	8525948
52571983	52572006	12	-	27260156	RDES	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.020007974223336222	[274]	[276,347,249,415]	0	hSpCas9	negative selection	8525949
52572472	52572495	12	-	27260156	RDES	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-1.0120097808213266	[394]	[206,173,273,253]	-9	hSpCas9	negative selection	8525950
52571964	52571987	12	+	27260156	PC3	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.08253302453023925	[235]	[132,268,385,291]	1	hSpCas9	negative selection	8582944
52571427	52571450	12	-	27260156	PC3	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.2822059011809745	[559]	[269,423,927,438]	-6	hSpCas9	negative selection	8582945
52571392	52571415	12	+	27260156	PC3	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.06412884243537542	[661]	[393,725,918,882]	1	hSpCas9	negative selection	8582946
52570713	52570736	12	+	27260156	PC3	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.07502346684797079	[1249]	[827,1144,2033,1631]	1	hSpCas9	negative selection	8647199
52571983	52572006	12	-	27260156	PC3	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.07133115267218315	[274]	[145,460,449,180]	1	hSpCas9	negative selection	8647200
52572472	52572495	12	-	27260156	PC3	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.620002908255334	[394]	[183,264,428,214]	-8	hSpCas9	negative selection	8647201
52571964	52571987	12	+	27260156	PATU8988T	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.5472726907051615	[235]	[291,541,328,176]	8	hSpCas9	negative selection	8704195
52571427	52571450	12	-	27260156	PATU8988T	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.020544414536775468	[559]	[471,611,529,590]	0	hSpCas9	negative selection	8704196
52571392	52571415	12	+	27260156	PATU8988T	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.12834899939041455	[661]	[869,625,598,695]	2	hSpCas9	negative selection	8704197
52570713	52570736	12	+	27260156	PATU8988T	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.04775744884622535	[1249]	[952,1255,1109,1380]	-1	hSpCas9	negative selection	8768450
52571983	52572006	12	-	27260156	PATU8988T	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.005486682206273574	[274]	[171,415,177,311]	0	hSpCas9	negative selection	8768451
52572472	52572495	12	-	27260156	PATU8988T	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	0.14238554687909297	[394]	[449,323,441,462]	2	hSpCas9	negative selection	8768452
52571964	52571987	12	+	27260156	T47D	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.263355495699658	[235]	[374,267,313,369]	5	hSpCas9	negative selection	8825446
52571427	52571450	12	-	27260156	T47D	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.28684740844558637	[559]	[560,459,418,712]	-6	hSpCas9	negative selection	8825447
52571392	52571415	12	+	27260156	T47D	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.14596412775454526	[661]	[831,877,763,940]	3	hSpCas9	negative selection	8825448
52570713	52570736	12	+	27260156	T47D	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.08429914521946791	[1249]	[1516,1457,1608,1598]	1	hSpCas9	negative selection	8889701
52571983	52572006	12	-	27260156	T47D	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.11735132107720225	[274]	[353,319,265,237]	-3	hSpCas9	negative selection	8889702
52572472	52572495	12	-	27260156	T47D	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.23423841806520368	[394]	[396,439,360,361]	-5	hSpCas9	negative selection	8889703
52571964	52571987	12	+	27260156	SU8686	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.27384489269343026	[235]	[249,246,210,455]	4	hSpCas9	negative selection	8946697
52571427	52571450	12	-	27260156	SU8686	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.21271925028531408	[559]	[484,475,448,505]	-4	hSpCas9	negative selection	8946698
52571392	52571415	12	+	27260156	SU8686	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.16517364629543385	[661]	[766,601,609,1014]	2	hSpCas9	negative selection	8946699
52570713	52570736	12	+	27260156	SU8686	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.24674113473863368	[1249]	[965,883,1066,1329]	-4	hSpCas9	negative selection	9010952
52571983	52572006	12	-	27260156	SU8686	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.042822070325093664	[274]	[255,266,185,361]	0	hSpCas9	negative selection	9010953
52572472	52572495	12	-	27260156	SU8686	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.19831856710411633	[394]	[336,308,284,452]	-3	hSpCas9	negative selection	9010954
52571964	52571987	12	+	27260156	SKES1	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.11840205837580275	[235]	[184,188,143,326]	-3	hSpCas9	negative selection	9067948
52571427	52571450	12	-	27260156	SKES1	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.15694386521000825	[559]	[625,480,510,406]	-3	hSpCas9	negative selection	9067949
52571392	52571415	12	+	27260156	SKES1	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.0405133662421755	[661]	[705,797,636,596]	0	hSpCas9	negative selection	9067950
52570713	52570736	12	+	27260156	SKES1	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.025467741404279876	[1249]	[1610,1491,1063,1004]	0	hSpCas9	negative selection	9132203
52571983	52572006	12	-	27260156	SKES1	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.0011956340662208076	[274]	[386,246,318,166]	0	hSpCas9	negative selection	9132204
52572472	52572495	12	-	27260156	SKES1	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.6725190239597676	[394]	[349,191,200,250]	-9	hSpCas9	negative selection	9132205
52571964	52571987	12	+	27260156	TOV112D	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.09276343256027764	[235]	[221,290,253,247]	1	hSpCas9	negative selection	9189199
52571427	52571450	12	-	27260156	TOV112D	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	0.012376598111543291	[559]	[451,871,594,412]	0	hSpCas9	negative selection	9189200
52571392	52571415	12	+	27260156	TOV112D	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.36356255984472796	[661]	[847,1107,877,644]	6	hSpCas9	negative selection	9189201
52570713	52570736	12	+	27260156	TOV112D	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	-0.10792906743917885	[1249]	[1251,1360,871,1214]	-2	hSpCas9	negative selection	9253454
52571983	52572006	12	-	27260156	TOV112D	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.3725894538324285	[274]	[187,341,161,188]	-6	hSpCas9	negative selection	9253455
52572472	52572495	12	-	27260156	TOV112D	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.6516370557570286	[394]	[207,371,244,208]	-8	hSpCas9	negative selection	9253456
52571964	52571987	12	+	27260156	TC71	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	-0.32897729003640097	[235]	[161,150,254,238]	-7	hSpCas9	negative selection	9310450
52571427	52571450	12	-	27260156	TC71	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.2588051117522398	[559]	[392,518,564,531]	-6	hSpCas9	negative selection	9310451
52571392	52571415	12	+	27260156	TC71	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.28569802853144666	[661]	[739,806,924,996]	7	hSpCas9	negative selection	9310452
52570713	52570736	12	+	27260156	TC71	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.05397392847511173	[1249]	[1351,1328,1126,1789]	1	hSpCas9	negative selection	9374705
52571983	52572006	12	-	27260156	TC71	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	-0.08959297107438702	[274]	[306,239,215,350]	-2	hSpCas9	negative selection	9374706
52572472	52572495	12	-	27260156	TC71	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.264350861505452	[394]	[362,357,389,293]	-6	hSpCas9	negative selection	9374707
52571964	52571987	12	+	27260156	TC32	viability	CATTCTCTGCTGTCGTGCGCCGG	KRT74	ENSG00000170484	0.3127312464965386	[235]	[248,249,337,270]	5	hSpCas9	negative selection	9431701
52571427	52571450	12	-	27260156	TC32	viability	AGATGCAGCCTACGCAGTCAAGG	KRT74	ENSG00000170484	-0.08910868839936517	[559]	[387,438,628,553]	-1	hSpCas9	negative selection	9431702
52571392	52571415	12	+	27260156	TC32	viability	TTTGTCCAGTGAGTCCACTTTGG	KRT74	ENSG00000170484	0.3948164021513292	[661]	[787,676,1061,791]	7	hSpCas9	negative selection	9431703
52570713	52570736	12	+	27260156	TC32	viability	CGATCTCCTCATAATGCATGCGG	KRT74	ENSG00000170484	0.29759782081002517	[1249]	[1206,1234,1909,1529]	5	hSpCas9	negative selection	9495956
52571983	52572006	12	-	27260156	TC32	viability	GATATGAAGTGGAGATTAACCGG	KRT74	ENSG00000170484	0.08669290931694706	[274]	[226,157,354,414]	1	hSpCas9	negative selection	9495957
52572472	52572495	12	-	27260156	TC32	viability	GCTGAGAAGCATGAGGGATCTGG	KRT74	ENSG00000170484	-0.13095869419204897	[394]	[252,252,388,502]	-2	hSpCas9	negative selection	9495958
52567016	52567039	12	-	27869803	HPAFII	viability after 27 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	1.5813121873200957	[35]	[12,92,NaN]	9	hSpCas9	negative selection	9547253
52567110	52567133	12	+	27869803	HPAFII	viability after 27 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	-0.2660084868917482	[277]	[90,146,NaN]	-2	hSpCas9	negative selection	9547254
52569885	52569908	12	+	27869803	HPAFII	viability after 27 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.2880037783478475	[204]	[60,110,NaN]	-2	hSpCas9	negative selection	9547255
52571424	52571447	12	-	27869803	HPAFII	viability after 27 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.10909245041711813	[475]	[162,358,NaN]	0	hSpCas9	negative selection	9547256
52573545	52573568	12	-	27869803	HPAFII	viability after 27 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.0877574792664535	[47]	[16,34,NaN]	0	hSpCas9	negative selection	9547257
52573657	52573680	12	-	27869803	HPAFII	viability after 27 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	-0.3501978432294417	[666]	[405,165,NaN]	-3	hSpCas9	negative selection	9547258
52567016	52567039	12	-	27869803	HPAFII	viability after 15 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	1.0379573202233645	[35]	[10,121,NaN]	9	hSpCas9	negative selection	9629702
52567110	52567133	12	+	27869803	HPAFII	viability after 15 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	-0.15959650692032915	[277]	[293,250,NaN]	-2	hSpCas9	negative selection	9629703
52569885	52569908	12	+	27869803	HPAFII	viability after 15 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.18822656000877924	[204]	[238,164,NaN]	-2	hSpCas9	negative selection	9629704
52571424	52571447	12	-	27869803	HPAFII	viability after 15 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.47260044055123307	[475]	[417,337,NaN]	-5	hSpCas9	negative selection	9629705
52573545	52573568	12	-	27869803	HPAFII	viability after 15 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.04655973276959857	[47]	[36,57,NaN]	0	hSpCas9	negative selection	9629706
52573657	52573680	12	-	27869803	HPAFII	viability after 15 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	-0.21056087730146467	[666]	[949,413,NaN]	-2	hSpCas9	negative selection	9629707
52567016	52567039	12	-	27869803	ASPC1	viability after 36 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	-0.9489186514566166	[88]	[0,17,24]	-7	hSpCas9	negative selection	9712151
52567110	52567133	12	+	27869803	ASPC1	viability after 36 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	1.113631620705643	[640]	[722,499,298]	9	hSpCas9	negative selection	9712152
52569885	52569908	12	+	27869803	ASPC1	viability after 36 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.5207464708773226	[488]	[244,102,41]	-5	hSpCas9	negative selection	9712153
52571424	52571447	12	-	27869803	ASPC1	viability after 36 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	1.2911249989695448	[1211]	[297,801,1726]	9	hSpCas9	negative selection	9712154
52573545	52573568	12	-	27869803	ASPC1	viability after 36 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-1.0097179776700205	[170]	[46,49,0]	-7	hSpCas9	negative selection	9712155
52573657	52573680	12	-	27869803	ASPC1	viability after 36 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.30521570995802083	[1441]	[522,1010,375]	3	hSpCas9	negative selection	9712156
52567016	52567039	12	-	27869803	PATU8988S	viability after 35 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	0.8342037935242239	[79]	[32,81,NaN]	8	hSpCas9	negative selection	9794600
52567110	52567133	12	+	27869803	PATU8988S	viability after 35 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.9816924203891966	[699]	[442,670,NaN]	8	hSpCas9	negative selection	9794601
52569885	52569908	12	+	27869803	PATU8988S	viability after 35 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.27054749418267887	[375]	[256,107,NaN]	3	hSpCas9	negative selection	9794602
52571424	52571447	12	-	27869803	PATU8988S	viability after 35 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.9627677387390017	[1037]	[210,217,NaN]	-7	hSpCas9	negative selection	9794603
52573545	52573568	12	-	27869803	PATU8988S	viability after 35 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.2777142612992347	[123]	[78,41,NaN]	3	hSpCas9	negative selection	9794604
52573657	52573680	12	-	27869803	PATU8988S	viability after 35 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.2920628150321476	[1215]	[659,538,NaN]	3	hSpCas9	negative selection	9794605
52567016	52567039	12	-	27869803	PATU8988S	viability after 31 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	0.5328580916864145	[79]	[6,95,NaN]	6	hSpCas9	negative selection	9877049
52567110	52567133	12	+	27869803	PATU8988S	viability after 31 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.9301818127457266	[699]	[475,602,NaN]	9	hSpCas9	negative selection	9877050
52569885	52569908	12	+	27869803	PATU8988S	viability after 31 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.008272669817481648	[375]	[101,208,NaN]	0	hSpCas9	negative selection	9877051
52571424	52571447	12	-	27869803	PATU8988S	viability after 31 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	-0.4564530407522346	[1037]	[287,318,NaN]	-5	hSpCas9	negative selection	9877052
52573545	52573568	12	-	27869803	PATU8988S	viability after 31 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	0.5398312554197398	[123]	[81,58,NaN]	6	hSpCas9	negative selection	9877053
52573657	52573680	12	-	27869803	PATU8988S	viability after 31 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	0.39293410020837327	[1215]	[571,718,NaN]	5	hSpCas9	negative selection	9877054
52567016	52567039	12	-	27869803	HPAFII	viability after 35 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	0.8379487251405517	[35]	[9,57,NaN]	5	hSpCas9	negative selection	9959498
52567110	52567133	12	+	27869803	HPAFII	viability after 35 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	0.5827865606728	[277]	[135,294,NaN]	4	hSpCas9	negative selection	9959499
52569885	52569908	12	+	27869803	HPAFII	viability after 35 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	-0.2782390810562124	[204]	[62,110,NaN]	-2	hSpCas9	negative selection	9959500
52571424	52571447	12	-	27869803	HPAFII	viability after 35 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.3513517320264675	[475]	[91,549,NaN]	2	hSpCas9	negative selection	9959501
52573545	52573568	12	-	27869803	HPAFII	viability after 35 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.5353386168882364	[47]	[20,11,NaN]	-3	hSpCas9	negative selection	9959502
52573657	52573680	12	-	27869803	HPAFII	viability after 35 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	-0.5732576406732641	[666]	[352,84,NaN]	-3	hSpCas9	negative selection	9959503
52567016	52567039	12	-	27869803	HPAFII	viability after 31 days	GGGAGACCTCAAGGACACCCAGG	KRT74	ENSG00000170484	1.5612052368530112	[35]	[39,80,NaN]	9	hSpCas9	negative selection	10041947
52567110	52567133	12	+	27869803	HPAFII	viability after 31 days	AAGGTCAACACCCGCAGAGCTGG	KRT74	ENSG00000170484	-0.14565314264550522	[277]	[85,200,NaN]	-1	hSpCas9	negative selection	10041948
52569885	52569908	12	+	27869803	HPAFII	viability after 31 days	ACCGGATCCTCTGGATGAGCCGG	KRT74	ENSG00000170484	0.026192205310193784	[204]	[75,161,NaN]	0	hSpCas9	negative selection	10041949
52571424	52571447	12	-	27869803	HPAFII	viability after 31 days	TGCAGCCTACGCAGTCAAGGTGG	KRT74	ENSG00000170484	0.2046371946950395	[475]	[136,493,NaN]	1	hSpCas9	negative selection	10041950
52573545	52573568	12	-	27869803	HPAFII	viability after 31 days	GGAGGTTACGGCTTCAGGCCTGG	KRT74	ENSG00000170484	-0.6382956285395189	[47]	[12,21,NaN]	-4	hSpCas9	negative selection	10041951
52573657	52573680	12	-	27869803	HPAFII	viability after 31 days	TTACTGTGCAGCTGGCAGAGGGG	KRT74	ENSG00000170484	-0.6009314135379601	[666]	[342,141,NaN]	-4	hSpCas9	negative selection	10041952
52568329	52568352	12	-	28162770	P31FUJ	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.38017467247637426	[237]	[363]	4	hSpCas9	negative selection	10181627
52572452	52572475	12	-	28162770	P31FUJ	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.36780863927226237	[702]	[1065]	4	hSpCas9	negative selection	10181628
52567651	52567674	12	+	28162770	P31FUJ	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-0.7853432274431573	[21]	[14]	-6	hSpCas9	negative selection	10181629
52573746	52573769	12	-	28162770	P31FUJ	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.5023701079287768	[321]	[535]	5	hSpCas9	negative selection	10181630
52573693	52573716	12	-	28162770	P31FUJ	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	-0.5397799578357698	[119]	[96]	-4	hSpCas9	negative selection	10181631
52573372	52573395	12	-	28162770	P31FUJ	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	-1.0093639729263797	[196]	[114]	-6	hSpCas9	negative selection	10181632
52573613	52573636	12	-	28162770	P31FUJ	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.4151053381353154	[277]	[244]	-4	hSpCas9	negative selection	10181633
52573420	52573443	12	+	28162770	P31FUJ	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	0.6614883544145063	[183]	[341]	7	hSpCas9	negative selection	10181634
52572517	52572540	12	-	28162770	P31FUJ	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	-0.3809008434035124	[450]	[406]	-3	hSpCas9	negative selection	10181635
52572466	52572489	12	-	28162770	P31FUJ	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.34596181183767194	[621]	[928]	4	hSpCas9	negative selection	10181636
52568329	52568352	12	-	28162770	TF1	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	NaN	[NaN]	[222]	1	hSpCas9	negative selection	10350993
52572452	52572475	12	-	28162770	TF1	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	NaN	[NaN]	[412]	1	hSpCas9	negative selection	10350994
52567651	52567674	12	+	28162770	TF1	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	NaN	[NaN]	[7]	1	hSpCas9	negative selection	10350995
52573746	52573769	12	-	28162770	TF1	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	NaN	[NaN]	[250]	1	hSpCas9	negative selection	10350996
52573693	52573716	12	-	28162770	TF1	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10350997
52573372	52573395	12	-	28162770	TF1	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	NaN	[NaN]	[330]	1	hSpCas9	negative selection	10350998
52573613	52573636	12	-	28162770	TF1	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	NaN	[NaN]	[237]	1	hSpCas9	negative selection	10350999
52573420	52573443	12	+	28162770	TF1	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	NaN	[NaN]	[73]	1	hSpCas9	negative selection	10351000
52572517	52572540	12	-	28162770	TF1	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10351001
52572466	52572489	12	-	28162770	TF1	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	NaN	[NaN]	[606]	1	hSpCas9	negative selection	10351002
52568329	52568352	12	-	28162770	SKM1	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	-0.43295940727610616	[83]	[109]	-4	hSpCas9	negative selection	10520359
52572452	52572475	12	-	28162770	SKM1	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	-0.04284366779505344	[154]	[265]	0	hSpCas9	negative selection	10520360
52567651	52567674	12	+	28162770	SKM1	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	2.463400520840243	[3]	[38]	9	hSpCas9	negative selection	10520361
52573746	52573769	12	-	28162770	SKM1	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.42592581542158026	[95]	[227]	4	hSpCas9	negative selection	10520362
52573693	52573716	12	-	28162770	SKM1	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	0.15375075573131713	[29]	[58]	1	hSpCas9	negative selection	10520363
52573372	52573395	12	-	28162770	SKM1	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	-0.023635559191655997	[45]	[79]	0	hSpCas9	negative selection	10520364
52573613	52573636	12	-	28162770	SKM1	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.3838805856301205	[61]	[83]	-3	hSpCas9	negative selection	10520365
52573420	52573443	12	+	28162770	SKM1	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	1.1529073210151641	[28]	[113]	9	hSpCas9	negative selection	10520366
52572517	52572540	12	-	28162770	SKM1	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	1.3955897370506214	[85]	[399]	9	hSpCas9	negative selection	10520367
52572466	52572489	12	-	28162770	SKM1	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.4738885359638334	[122]	[301]	4	hSpCas9	negative selection	10520368
52568329	52568352	12	-	28162770	SKM1	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	-0.43295940727610616	[83]	[109]	-4	hSpCas9	negative selection	10689725
52572452	52572475	12	-	28162770	SKM1	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	-0.04284366779505344	[154]	[265]	0	hSpCas9	negative selection	10689726
52567651	52567674	12	+	28162770	SKM1	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	2.463400520840243	[3]	[38]	9	hSpCas9	negative selection	10689727
52573746	52573769	12	-	28162770	SKM1	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.42592581542158026	[95]	[227]	4	hSpCas9	negative selection	10689728
52573693	52573716	12	-	28162770	SKM1	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	0.15375075573131713	[29]	[58]	1	hSpCas9	negative selection	10689729
52573372	52573395	12	-	28162770	SKM1	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	-0.023635559191655997	[45]	[79]	0	hSpCas9	negative selection	10689730
52573613	52573636	12	-	28162770	SKM1	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.3838805856301205	[61]	[83]	-3	hSpCas9	negative selection	10689731
52573420	52573443	12	+	28162770	SKM1	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	1.1529073210151641	[28]	[113]	9	hSpCas9	negative selection	10689732
52572517	52572540	12	-	28162770	SKM1	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	1.3955897370506214	[85]	[399]	9	hSpCas9	negative selection	10689733
52572466	52572489	12	-	28162770	SKM1	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.4738885359638334	[122]	[301]	4	hSpCas9	negative selection	10689734
52568329	52568352	12	-	28162770	PL21	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.7942621144959523	[313]	[236]	6	hSpCas9	negative selection	10859091
52572452	52572475	12	-	28162770	PL21	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.8391978592513865	[505]	[393]	7	hSpCas9	negative selection	10859092
52567651	52567674	12	+	28162770	PL21	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-2.7998603855106805	[15]	[0]	-9	hSpCas9	negative selection	10859093
52573746	52573769	12	-	28162770	PL21	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	-0.554248425996704	[360]	[106]	-4	hSpCas9	negative selection	10859094
52573693	52573716	12	-	28162770	PL21	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	-0.014873276481530251	[129]	[55]	0	hSpCas9	negative selection	10859095
52573372	52573395	12	-	28162770	PL21	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	1.092611150184875	[180]	[167]	8	hSpCas9	negative selection	10859096
52573613	52573636	12	-	28162770	PL21	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	0.49768355074972337	[178]	[109]	4	hSpCas9	negative selection	10859097
52573420	52573443	12	+	28162770	PL21	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	0.37463734572145657	[139]	[78]	3	hSpCas9	negative selection	10859098
52572517	52572540	12	-	28162770	PL21	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.9068752778541014	[298]	[243]	7	hSpCas9	negative selection	10859099
52572466	52572489	12	-	28162770	PL21	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.3570456694617705	[469]	[261]	3	hSpCas9	negative selection	10859100
52568329	52568352	12	-	28162770	P31FUJ	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.38017467247637426	[237]	[363]	4	hSpCas9	negative selection	11028457
52572452	52572475	12	-	28162770	P31FUJ	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.36780863927226237	[702]	[1065]	4	hSpCas9	negative selection	11028458
52567651	52567674	12	+	28162770	P31FUJ	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-0.7853432274431573	[21]	[14]	-6	hSpCas9	negative selection	11028459
52573746	52573769	12	-	28162770	P31FUJ	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.5023701079287768	[321]	[535]	5	hSpCas9	negative selection	11028460
52573693	52573716	12	-	28162770	P31FUJ	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	-0.5397799578357698	[119]	[96]	-4	hSpCas9	negative selection	11028461
52573372	52573395	12	-	28162770	P31FUJ	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	-1.0093639729263797	[196]	[114]	-6	hSpCas9	negative selection	11028462
52573613	52573636	12	-	28162770	P31FUJ	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.4151053381353154	[277]	[244]	-4	hSpCas9	negative selection	11028463
52573420	52573443	12	+	28162770	P31FUJ	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	0.6614883544145063	[183]	[341]	7	hSpCas9	negative selection	11028464
52572517	52572540	12	-	28162770	P31FUJ	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	-0.3809008434035124	[450]	[406]	-3	hSpCas9	negative selection	11028465
52572466	52572489	12	-	28162770	P31FUJ	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.34596181183767194	[621]	[928]	4	hSpCas9	negative selection	11028466
52568329	52568352	12	-	28162770	OCIAML5	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.5885060205219843	[111]	[303]	5	hSpCas9	negative selection	11197823
52572452	52572475	12	-	28162770	OCIAML5	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.31571951982198065	[449]	[1010]	2	hSpCas9	negative selection	11197824
52567651	52567674	12	+	28162770	OCIAML5	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	0.26341064655593893	[17]	[38]	2	hSpCas9	negative selection	11197825
52573746	52573769	12	-	28162770	OCIAML5	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.2108853347639249	[212]	[444]	1	hSpCas9	negative selection	11197826
52573693	52573716	12	-	28162770	OCIAML5	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	1.2006748912079763	[46]	[194]	8	hSpCas9	negative selection	11197827
52573372	52573395	12	-	28162770	OCIAML5	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	-0.5176475317934376	[114]	[144]	-4	hSpCas9	negative selection	11197828
52573613	52573636	12	-	28162770	OCIAML5	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	0.6610030113753735	[143]	[410]	6	hSpCas9	negative selection	11197829
52573420	52573443	12	+	28162770	OCIAML5	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	0.7710791237450471	[86]	[267]	6	hSpCas9	negative selection	11197830
52572517	52572540	12	-	28162770	OCIAML5	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.07813139823659054	[306]	[584]	0	hSpCas9	negative selection	11197831
52572466	52572489	12	-	28162770	OCIAML5	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.7436451709488514	[311]	[942]	6	hSpCas9	negative selection	11197832
52568329	52568352	12	-	28162770	EOL1	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.2271845278491369	[526]	[324]	2	hSpCas9	negative selection	11367189
52572452	52572475	12	-	28162770	EOL1	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.6890770053437743	[590]	[501]	6	hSpCas9	negative selection	11367190
52567651	52567674	12	+	28162770	EOL1	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	0.9245477715705346	[44]	[44]	7	hSpCas9	negative selection	11367191
52573746	52573769	12	-	28162770	EOL1	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.11919520242407822	[539]	[308]	1	hSpCas9	negative selection	11367192
52573693	52573716	12	-	28162770	EOL1	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	-0.06227683968173242	[217]	[109]	0	hSpCas9	negative selection	11367193
52573372	52573395	12	-	28162770	EOL1	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.9480832860313235	[303]	[308]	7	hSpCas9	negative selection	11367194
52573613	52573636	12	-	28162770	EOL1	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-1.1959650357466995	[286]	[65]	-7	hSpCas9	negative selection	11367195
52573420	52573443	12	+	28162770	EOL1	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	-0.20820743728123703	[181]	[82]	-1	hSpCas9	negative selection	11367196
52572517	52572540	12	-	28162770	EOL1	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.8398250926651075	[525]	[495]	7	hSpCas9	negative selection	11367197
52572466	52572489	12	-	28162770	EOL1	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.7488330895780159	[592]	[524]	6	hSpCas9	negative selection	11367198
52568329	52568352	12	-	28162770	MOLM13	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.359786774235203	[373]	[346]	2	hSpCas9	negative selection	11536555
52572452	52572475	12	-	28162770	MOLM13	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	-0.5280975559487977	[717]	[359]	-3	hSpCas9	negative selection	11536556
52567651	52567674	12	+	28162770	MOLM13	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-0.07267899981812409	[47]	[32]	0	hSpCas9	negative selection	11536557
52573746	52573769	12	-	28162770	MOLM13	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.122358387353795	[492]	[387]	0	hSpCas9	negative selection	11536558
52573693	52573716	12	-	28162770	MOLM13	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	-0.23456668219501808	[178]	[109]	-1	hSpCas9	negative selection	11536559
52573372	52573395	12	-	28162770	MOLM13	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.8316687611181898	[264]	[340]	6	hSpCas9	negative selection	11536560
52573613	52573636	12	-	28162770	MOLM13	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	0.5979499221089518	[211]	[231]	4	hSpCas9	negative selection	11536561
52573420	52573443	12	+	28162770	MOLM13	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	-2.0810038644690554	[157]	[26]	-7	hSpCas9	negative selection	11536562
52572517	52572540	12	-	28162770	MOLM13	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.2064842192954437	[530]	[442]	1	hSpCas9	negative selection	11536563
52572466	52572489	12	-	28162770	MOLM13	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	1.3558225801173824	[668]	[1237]	9	hSpCas9	negative selection	11536564
52568329	52568352	12	-	28162770	HEL	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.07025184482626112	[402]	[270]	0	hSpCas9	negative selection	11705921
52572452	52572475	12	-	28162770	HEL	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.5605897906464854	[541]	[511]	5	hSpCas9	negative selection	11705922
52567651	52567674	12	+	28162770	HEL	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-0.09422676216584946	[39]	[23]	0	hSpCas9	negative selection	11705923
52573746	52573769	12	-	28162770	HEL	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.5671412131061977	[332]	[315]	5	hSpCas9	negative selection	11705924
52573693	52573716	12	-	28162770	HEL	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	-0.2298818615234155	[129]	[70]	-2	hSpCas9	negative selection	11705925
52573372	52573395	12	-	28162770	HEL	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.8795416962609712	[184]	[217]	7	hSpCas9	negative selection	11705926
52573613	52573636	12	-	28162770	HEL	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.4264231925070387	[234]	[111]	-3	hSpCas9	negative selection	11705927
52573420	52573443	12	+	28162770	HEL	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	0.3009503147521517	[127]	[100]	2	hSpCas9	negative selection	11705928
52572517	52572540	12	-	28162770	HEL	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.33348456714810515	[424]	[342]	2	hSpCas9	negative selection	11705929
52572466	52572489	12	-	28162770	HEL	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.4539771885451891	[423]	[371]	4	hSpCas9	negative selection	11705930
52568329	52568352	12	-	28162770	MV411	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.41982659217656865	[259]	[292]	4	hSpCas9	negative selection	11875287
52572452	52572475	12	-	28162770	MV411	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.6499841058784219	[434]	[574]	6	hSpCas9	negative selection	11875288
52567651	52567674	12	+	28162770	MV411	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-0.4046391457969176	[21]	[13]	-3	hSpCas9	negative selection	11875289
52573746	52573769	12	-	28162770	MV411	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.7009846131682157	[267]	[366]	6	hSpCas9	negative selection	11875290
52573693	52573716	12	-	28162770	MV411	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	1.2474375507827753	[120]	[241]	9	hSpCas9	negative selection	11875291
52573372	52573395	12	-	28162770	MV411	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.7199253222455191	[159]	[221]	6	hSpCas9	negative selection	11875292
52573613	52573636	12	-	28162770	MV411	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.1794936270773218	[202]	[150]	-1	hSpCas9	negative selection	11875293
52573420	52573443	12	+	28162770	MV411	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	-0.4413607609229211	[107]	[66]	-3	hSpCas9	negative selection	11875294
52572517	52572540	12	-	28162770	MV411	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.6613947841624831	[333]	[444]	6	hSpCas9	negative selection	11875295
52572466	52572489	12	-	28162770	MV411	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	-0.08653457980956869	[420]	[333]	0	hSpCas9	negative selection	11875296
52568329	52568352	12	-	28162770	MONOMAC1	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.399170410829225	[212]	[321]	4	hSpCas9	negative selection	12044653
52572452	52572475	12	-	28162770	MONOMAC1	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	-0.07901487270258434	[304]	[330]	0	hSpCas9	negative selection	12044654
52567651	52567674	12	+	28162770	MONOMAC1	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-1.1970368470595538	[23]	[11]	-7	hSpCas9	negative selection	12044655
52573746	52573769	12	-	28162770	MONOMAC1	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.5684978993034234	[219]	[373]	5	hSpCas9	negative selection	12044656
52573693	52573716	12	-	28162770	MONOMAC1	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	1.058220208182521	[61]	[147]	8	hSpCas9	negative selection	12044657
52573372	52573395	12	-	28162770	MONOMAC1	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.18674971823485037	[104]	[136]	2	hSpCas9	negative selection	12044658
52573613	52573636	12	-	28162770	MONOMAC1	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	0.6405326880450583	[107]	[192]	6	hSpCas9	negative selection	12044659
52573420	52573443	12	+	28162770	MONOMAC1	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	-0.514519036915724	[80]	[64]	-4	hSpCas9	negative selection	12044660
52572517	52572540	12	-	28162770	MONOMAC1	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.2499435447220445	[200]	[273]	2	hSpCas9	negative selection	12044661
52572466	52572489	12	-	28162770	MONOMAC1	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.7557485145196141	[263]	[510]	7	hSpCas9	negative selection	12044662
52568329	52568352	12	-	28162770	OCIAML2	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	-0.18799086146885613	[66]	[325]	-1	hSpCas9	negative selection	12214019
52572452	52572475	12	-	28162770	OCIAML2	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	0.9977165182028835	[87]	[973]	8	hSpCas9	negative selection	12214020
52567651	52567674	12	+	28162770	OCIAML2	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	1.658653191702805	[1]	[34]	9	hSpCas9	negative selection	12214021
52573746	52573769	12	-	28162770	OCIAML2	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.24291688154040791	[58]	[386]	2	hSpCas9	negative selection	12214022
52573693	52573716	12	-	28162770	OCIAML2	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	0.10539955070898721	[26]	[160]	1	hSpCas9	negative selection	12214023
52573372	52573395	12	-	28162770	OCIAML2	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.3199168091288889	[36]	[255]	3	hSpCas9	negative selection	12214024
52573613	52573636	12	-	28162770	OCIAML2	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	-0.09425394633242262	[25]	[134]	-1	hSpCas9	negative selection	12214025
52573420	52573443	12	+	28162770	OCIAML2	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	-0.6262806957023554	[21]	[78]	-5	hSpCas9	negative selection	12214026
52572517	52572540	12	-	28162770	OCIAML2	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.15497465997634086	[69]	[431]	1	hSpCas9	negative selection	12214027
52572466	52572489	12	-	28162770	OCIAML2	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.49818851950955945	[75]	[594]	5	hSpCas9	negative selection	12214028
52568329	52568352	12	-	28162770	OCIAML3	viability	GCGGGGAGACAATGCCCTGAAGG	KRT74	ENSG00000170484	0.4322716844746857	[67]	[276]	4	hSpCas9	negative selection	12383385
52572452	52572475	12	-	28162770	OCIAML3	viability	TGGTGGAGGACTATAAGAAGAGG	KRT74	ENSG00000170484	-0.13832815654797348	[139]	[383]	-1	hSpCas9	negative selection	12383386
52567651	52567674	12	+	28162770	OCIAML3	viability	ATACTCACAGATGCTCACAGAGG	KRT74	ENSG00000170484	-1.0090451396030065	[5]	[8]	-6	hSpCas9	negative selection	12383387
52573746	52573769	12	-	28162770	OCIAML3	viability	CAACTGAACATCAAGTCCAGTGG	KRT74	ENSG00000170484	0.884964164708779	[79]	[445]	7	hSpCas9	negative selection	12383388
52573693	52573716	12	-	28162770	OCIAML3	viability	AGTGGTGCCAAGGAAGGCTGTGG	KRT74	ENSG00000170484	0.8348356584797112	[25]	[139]	7	hSpCas9	negative selection	12383389
52573372	52573395	12	-	28162770	OCIAML3	viability	GCTGGACCCTGAGATCCAGAAGG	KRT74	ENSG00000170484	0.07294823259430067	[56]	[180]	0	hSpCas9	negative selection	12383390
52573613	52573636	12	-	28162770	OCIAML3	viability	GGAGCCTCTATAGCCTTGGAGGG	KRT74	ENSG00000170484	0.1429579538420429	[41]	[139]	1	hSpCas9	negative selection	12383391
52573420	52573443	12	+	28162770	OCIAML3	viability	TCTTGTTGACAGTGACCTGGTGG	KRT74	ENSG00000170484	-0.912183600350418	[47]	[76]	-6	hSpCas9	negative selection	12383392
52572517	52572540	12	-	28162770	OCIAML3	viability	GCAGCTGGAGACACTGTCTGGGG	KRT74	ENSG00000170484	0.06396965769521423	[121]	[384]	0	hSpCas9	negative selection	12383393
52572466	52572489	12	-	28162770	OCIAML3	viability	AAGCATGAGGGATCTGGTGGAGG	KRT74	ENSG00000170484	0.8499812326508096	[110]	[603]	7	hSpCas9	negative selection	12383394