| 52697722 | 52697745 | 12 | - | 26472758 | Jiyoye | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.48590941457761483 | [25] | [13] | -3 | hSpCas9 | negative selection | 86694 | 52692566 | 52692589 | 12 | + | 26472758 | Jiyoye | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | -0.011276782185735135 | [281] | [210] | 0 | hSpCas9 | negative selection | 86695 | 52692551 | 52692574 | 12 | - | 26472758 | Jiyoye | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.4203507702536067 | [108] | [109] | 3 | hSpCas9 | negative selection | 86696 | 52703271 | 52703294 | 12 | - | 26472758 | Jiyoye | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 1.8294083821889213 | [49] | [133] | 8 | hSpCas9 | negative selection | 86697 | 52702975 | 52702998 | 12 | - | 26472758 | Jiyoye | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | -0.6693869556407015 | [444] | [210] | -5 | hSpCas9 | negative selection | 86698 | 52697768 | 52697791 | 12 | - | 26472758 | Jiyoye | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 3.1296414059769644 | [14] | [98] | 9 | hSpCas9 | negative selection | 86699 | 52697722 | 52697745 | 12 | - | 26472758 | KBM7 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.30301425850734054 | [61,49] | [7,53] | 3 | hSpCas9 | negative selection | 277812 | 52692566 | 52692589 | 12 | + | 26472758 | KBM7 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.17430180926463645 | [1096,1032] | [696,448] | 1 | hSpCas9 | negative selection | 277813 | 52692551 | 52692574 | 12 | - | 26472758 | KBM7 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.17639587382321095 | [406,329] | [219,171] | 1 | hSpCas9 | negative selection | 277814 | 52703271 | 52703294 | 12 | - | 26472758 | KBM7 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.11944655283377204 | [338,353] | [220,139] | 1 | hSpCas9 | negative selection | 277815 | 52702975 | 52702998 | 12 | - | 26472758 | KBM7 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.39043984209211025 | [985,857] | [642,498] | 4 | hSpCas9 | negative selection | 277816 | 52697768 | 52697791 | 12 | - | 26472758 | KBM7 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | -0.45041890657075345 | [694,456] | [185,202] | -4 | hSpCas9 | negative selection | 277817 | 52697722 | 52697745 | 12 | - | 26472758 | Raji | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -1.5555814773488303 | [37] | [2] | -8 | hSpCas9 | negative selection | 468930 | 52692566 | 52692589 | 12 | + | 26472758 | Raji | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.13385574673479061 | [431] | [109] | 1 | hSpCas9 | negative selection | 468931 | 52692551 | 52692574 | 12 | - | 26472758 | Raji | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.08353679341923181 | [182] | [44] | 0 | hSpCas9 | negative selection | 468932 | 52703271 | 52703294 | 12 | - | 26472758 | Raji | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | -0.28493388740516074 | [251] | [47] | -2 | hSpCas9 | negative selection | 468933 | 52702975 | 52702998 | 12 | - | 26472758 | Raji | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | -0.7512270452062025 | [572] | [78] | -5 | hSpCas9 | negative selection | 468934 | 52697768 | 52697791 | 12 | - | 26472758 | Raji | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | -0.45134742377437703 | [217] | [36] | -4 | hSpCas9 | negative selection | 468935 | 52697722 | 52697745 | 12 | - | 26472758 | K562 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 1.1425391136472332 | [21] | [40] | 8 | hSpCas9 | negative selection | 660048 | 52692566 | 52692589 | 12 | + | 26472758 | K562 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.5805771762203596 | [685] | [865] | 5 | hSpCas9 | negative selection | 660049 | 52692551 | 52692574 | 12 | - | 26472758 | K562 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.5162720803555126 | [298] | [360] | 4 | hSpCas9 | negative selection | 660050 | 52703271 | 52703294 | 12 | - | 26472758 | K562 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | -0.05666258231531135 | [291] | [236] | 0 | hSpCas9 | negative selection | 660051 | 52702975 | 52702998 | 12 | - | 26472758 | K562 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.3935902303283343 | [917] | [1017] | 3 | hSpCas9 | negative selection | 660052 | 52697768 | 52697791 | 12 | - | 26472758 | K562 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | -0.2087934746386251 | [433] | [316] | -1 | hSpCas9 | negative selection | 660053 | 52691314 | 52691337 | 12 | - | 26627737 | DLD1 | viability | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 1.989751151904971 | [42] | [64,89,12] | 9 | hSpCas9 | negative selection | 784283 | 52697806 | 52697829 | 12 | - | 26627737 | DLD1 | viability | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.034264707595805355 | [1533] | [472,515,485] | 0 | hSpCas9 | negative selection | 784284 | 52698194 | 52698217 | 12 | - | 26627737 | DLD1 | viability | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.0994859963597845 | [335] | [209,258,209] | 8 | hSpCas9 | negative selection | 784285 | 52703306 | 52703329 | 12 | - | 26627737 | DLD1 | viability | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.8632902231482281 | [739] | [392,468,404] | 8 | hSpCas9 | negative selection | 784286 | 52691314 | 52691337 | 12 | - | 26627737 | GBM cells | viability after 5 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -0.194195529505796 | [79] | [37,36] | -3 | hSpCas9 | negative selection | 866598 | 52697806 | 52697829 | 12 | - | 26627737 | GBM cells | viability after 5 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.1145607781896969 | [979] | [621,515] | 1 | hSpCas9 | negative selection | 866599 | 52698194 | 52698217 | 12 | - | 26627737 | GBM cells | viability after 5 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.3825551881635532 | [230] | [142,179] | 6 | hSpCas9 | negative selection | 866600 | 52703306 | 52703329 | 12 | - | 26627737 | GBM cells | viability after 5 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.3085981396703227 | [404] | [290,246] | 5 | hSpCas9 | negative selection | 866601 | 52691314 | 52691337 | 12 | - | 26627737 | GBM cells | viability after 13 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.07308974054858952 | [79] | [59,33] | 0 | hSpCas9 | negative selection | 948913 | 52697806 | 52697829 | 12 | - | 26627737 | GBM cells | viability after 13 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.3409835693185388 | [979] | [694,655] | 4 | hSpCas9 | negative selection | 948914 | 52698194 | 52698217 | 12 | - | 26627737 | GBM cells | viability after 13 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.03581351604382589 | [230] | [133,123] | 0 | hSpCas9 | negative selection | 948915 | 52703306 | 52703329 | 12 | - | 26627737 | GBM cells | viability after 13 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.3408678643165771 | [404] | [274,280] | 4 | hSpCas9 | negative selection | 948916 | 52691314 | 52691337 | 12 | - | 26627737 | GBM cells | viability after 21 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.44501791839918425 | [79] | [66,51] | 4 | hSpCas9 | negative selection | 1031228 | 52697806 | 52697829 | 12 | - | 26627737 | GBM cells | viability after 21 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.1711845649223076 | [979] | [634,566] | 1 | hSpCas9 | negative selection | 1031229 | 52698194 | 52698217 | 12 | - | 26627737 | GBM cells | viability after 21 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | -0.5784351901803124 | [230] | [82,84] | -5 | hSpCas9 | negative selection | 1031230 | 52703306 | 52703329 | 12 | - | 26627737 | GBM cells | viability after 21 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.4563290506233336 | [404] | [327,277] | 5 | hSpCas9 | negative selection | 1031231 | 52691314 | 52691337 | 12 | - | 26627737 | RPE1 | viability after 9 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 1.8113677359243419 | [138] | [81,243] | 8 | hSpCas9 | negative selection | 1113543 | 52697806 | 52697829 | 12 | - | 26627737 | RPE1 | viability after 9 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.6699051695242215 | [2016] | [884,1158] | 4 | hSpCas9 | negative selection | 1113544 | 52698194 | 52698217 | 12 | - | 26627737 | RPE1 | viability after 9 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.7698382141150009 | [591] | [136,546] | 5 | hSpCas9 | negative selection | 1113545 | 52703306 | 52703329 | 12 | - | 26627737 | RPE1 | viability after 9 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.08168800080771965 | [1621] | [260,893] | 0 | hSpCas9 | negative selection | 1113546 | 52691314 | 52691337 | 12 | - | 26627737 | RPE1 | viability after 12 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 1.284058763640585 | [138] | [54,128] | 7 | hSpCas9 | negative selection | 1195858 | 52697806 | 52697829 | 12 | - | 26627737 | RPE1 | viability after 12 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.78614484213793 | [2016] | [712,1168] | 5 | hSpCas9 | negative selection | 1195859 | 52698194 | 52698217 | 12 | - | 26627737 | RPE1 | viability after 12 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.534118135833544 | [591] | [172,290] | 3 | hSpCas9 | negative selection | 1195860 | 52703306 | 52703329 | 12 | - | 26627737 | RPE1 | viability after 12 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.25848382098274225 | [1621] | [343,708] | 1 | hSpCas9 | negative selection | 1195861 | 52691314 | 52691337 | 12 | - | 26627737 | RPE1 | viability after 15 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 1.4578766261350553 | [138] | [50,162] | 7 | hSpCas9 | negative selection | 1278173 | 52697806 | 52697829 | 12 | - | 26627737 | RPE1 | viability after 15 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.9980103234519333 | [2016] | [1051,1223] | 6 | hSpCas9 | negative selection | 1278174 | 52698194 | 52698217 | 12 | - | 26627737 | RPE1 | viability after 15 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.2239712922685195 | [591] | [324,454] | 7 | hSpCas9 | negative selection | 1278175 | 52703306 | 52703329 | 12 | - | 26627737 | RPE1 | viability after 15 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.11361056707529582 | [1621] | [303,681] | 0 | hSpCas9 | negative selection | 1278176 | 52691314 | 52691337 | 12 | - | 26627737 | RPE1 | viability after 18 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 1.8905534094480263 | [138] | [24,260] | 8 | hSpCas9 | negative selection | 1360488 | 52697806 | 52697829 | 12 | - | 26627737 | RPE1 | viability after 18 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 1.1817467461514475 | [2016] | [762,1738] | 6 | hSpCas9 | negative selection | 1360489 | 52698194 | 52698217 | 12 | - | 26627737 | RPE1 | viability after 18 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.9084180861378308 | [591] | [164,443] | 5 | hSpCas9 | negative selection | 1360490 | 52703306 | 52703329 | 12 | - | 26627737 | RPE1 | viability after 18 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.05933000773449271 | [1621] | [327,592] | 0 | hSpCas9 | negative selection | 1360491 | 52691314 | 52691337 | 12 | - | 26627737 | HeLa | viability after 8 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -2.7587663244493976 | [211] | [34,2,7] | -9 | hSpCas9 | negative selection | 1442803 | 52697806 | 52697829 | 12 | - | 26627737 | HeLa | viability after 8 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.22996373930532243 | [1249] | [688,642,595] | 2 | hSpCas9 | negative selection | 1442804 | 52698194 | 52698217 | 12 | - | 26627737 | HeLa | viability after 8 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.7001466948758853 | [176] | [161,162,62] | 6 | hSpCas9 | negative selection | 1442805 | 52703306 | 52703329 | 12 | - | 26627737 | HeLa | viability after 8 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.01639660187784009 | [777] | [408,247,381] | 0 | hSpCas9 | negative selection | 1442806 | 52691314 | 52691337 | 12 | - | 26627737 | HeLa | viability after 12 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -1.2573616485020187 | [211] | [8,37,61] | -8 | hSpCas9 | negative selection | 1525118 | 52697806 | 52697829 | 12 | - | 26627737 | HeLa | viability after 12 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | -0.21349213268558898 | [1249] | [411,403,523] | -2 | hSpCas9 | negative selection | 1525119 | 52698194 | 52698217 | 12 | - | 26627737 | HeLa | viability after 12 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.36932104853763 | [176] | [151,281,121] | 8 | hSpCas9 | negative selection | 1525120 | 52703306 | 52703329 | 12 | - | 26627737 | HeLa | viability after 12 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.06757682933483389 | [777] | [452,300,263] | 0 | hSpCas9 | negative selection | 1525121 | 52691314 | 52691337 | 12 | - | 26627737 | HeLa | viability after 15 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -0.45966885812683556 | [211] | [62,101,19] | -4 | hSpCas9 | negative selection | 1607433 | 52697806 | 52697829 | 12 | - | 26627737 | HeLa | viability after 15 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.219066471691866 | [1249] | [691,390,700] | 1 | hSpCas9 | negative selection | 1607434 | 52698194 | 52698217 | 12 | - | 26627737 | HeLa | viability after 15 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.3810715855644382 | [176] | [110,301,147] | 8 | hSpCas9 | negative selection | 1607435 | 52703306 | 52703329 | 12 | - | 26627737 | HeLa | viability after 15 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.7502349870784142 | [777] | [258,55,253] | -6 | hSpCas9 | negative selection | 1607436 | 52691314 | 52691337 | 12 | - | 26627737 | HeLa | viability after 18 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -0.42738878568469785 | [211] | [46,81,19] | -4 | hSpCas9 | negative selection | 1689748 | 52697806 | 52697829 | 12 | - | 26627737 | HeLa | viability after 18 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.21641440178275428 | [1249] | [453,333,700] | 1 | hSpCas9 | negative selection | 1689749 | 52698194 | 52698217 | 12 | - | 26627737 | HeLa | viability after 18 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.361462798697057 | [176] | [67,251,147] | 8 | hSpCas9 | negative selection | 1689750 | 52703306 | 52703329 | 12 | - | 26627737 | HeLa | viability after 18 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.805136217128829 | [777] | [157,48,253] | -6 | hSpCas9 | negative selection | 1689751 | 52691314 | 52691337 | 12 | - | 26627737 | HCT116 | viability after 6 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -0.5309600616755805 | [116] | [33,0] | -3 | hSpCas9 | negative selection | 1772063 | 52697806 | 52697829 | 12 | - | 26627737 | HCT116 | viability after 6 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.7121966488767482 | [1999] | [556,491] | 4 | hSpCas9 | negative selection | 1772064 | 52698194 | 52698217 | 12 | - | 26627737 | HCT116 | viability after 6 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.7299553100099709 | [844] | [122,273] | 4 | hSpCas9 | negative selection | 1772065 | 52703306 | 52703329 | 12 | - | 26627737 | HCT116 | viability after 6 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -2.113832668091965 | [1797] | [112,38] | -8 | hSpCas9 | negative selection | 1772066 | 52691314 | 52691337 | 12 | - | 26627737 | HCT116 | viability after 8 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.8567819782180834 | [78] | [47,112,74] | 7 | hSpCas9 | negative selection | 1854378 | 52697806 | 52697829 | 12 | - | 26627737 | HCT116 | viability after 8 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.7148581160467564 | [717] | [629,605,710] | 6 | hSpCas9 | negative selection | 1854379 | 52698194 | 52698217 | 12 | - | 26627737 | HCT116 | viability after 8 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | -0.2817194738417712 | [404] | [252,199,99] | -3 | hSpCas9 | negative selection | 1854380 | 52703306 | 52703329 | 12 | - | 26627737 | HCT116 | viability after 8 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.4538789239109916 | [550] | [307,465,470] | 5 | hSpCas9 | negative selection | 1854381 | 52691314 | 52691337 | 12 | - | 26627737 | HCT116 | viability after 9 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 2.4338115850961115 | [116] | [184,155] | 9 | hSpCas9 | negative selection | 1936693 | 52697806 | 52697829 | 12 | - | 26627737 | HCT116 | viability after 9 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | -0.04147924288919613 | [1999] | [681,389] | 0 | hSpCas9 | negative selection | 1936694 | 52698194 | 52698217 | 12 | - | 26627737 | HCT116 | viability after 9 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.5742675904948193 | [844] | [407,278] | 4 | hSpCas9 | negative selection | 1936695 | 52703306 | 52703329 | 12 | - | 26627737 | HCT116 | viability after 9 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.44965107021794415 | [1797] | [467,803] | 3 | hSpCas9 | negative selection | 1936696 | 52691314 | 52691337 | 12 | - | 26627737 | HCT116 | viability after 12 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.43447466030516657 | [78] | [22,87,60] | 4 | hSpCas9 | negative selection | 2019008 | 52697806 | 52697829 | 12 | - | 26627737 | HCT116 | viability after 12 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.5344576695094587 | [717] | [580,606,449] | 5 | hSpCas9 | negative selection | 2019009 | 52698194 | 52698217 | 12 | - | 26627737 | HCT116 | viability after 12 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | -0.16397735004670078 | [404] | [210,145,209] | -2 | hSpCas9 | negative selection | 2019010 | 52703306 | 52703329 | 12 | - | 26627737 | HCT116 | viability after 12 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.47694654263112246 | [550] | [385,421,402] | 4 | hSpCas9 | negative selection | 2019011 | 52691314 | 52691337 | 12 | - | 26627737 | HCT116 | viability after 15 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.6827725751470388 | [78] | [33,43,134] | 6 | hSpCas9 | negative selection | 2101323 | 52697806 | 52697829 | 12 | - | 26627737 | HCT116 | viability after 15 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.8974715074772692 | [717] | [1040,565,730] | 7 | hSpCas9 | negative selection | 2101324 | 52698194 | 52698217 | 12 | - | 26627737 | HCT116 | viability after 15 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | -0.48100725305278125 | [404] | [159,244,94] | -5 | hSpCas9 | negative selection | 2101325 | 52703306 | 52703329 | 12 | - | 26627737 | HCT116 | viability after 15 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.22516458471816925 | [550] | [319,447,335] | 2 | hSpCas9 | negative selection | 2101326 | 52691314 | 52691337 | 12 | - | 26627737 | HCT116 | viability after 18 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.27320905764275083 | [78] | [16,44,77] | 2 | hSpCas9 | negative selection | 2183638 | 52697806 | 52697829 | 12 | - | 26627737 | HCT116 | viability after 18 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.8004027674723917 | [717] | [537,482,809] | 6 | hSpCas9 | negative selection | 2183639 | 52698194 | 52698217 | 12 | - | 26627737 | HCT116 | viability after 18 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | -0.694230076912825 | [404] | [183,103,73] | -6 | hSpCas9 | negative selection | 2183640 | 52703306 | 52703329 | 12 | - | 26627737 | HCT116 | viability after 18 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.5772827558646415 | [550] | [370,496,313] | 5 | hSpCas9 | negative selection | 2183641 | 52703238 | 52703261 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | AGGAGCCTCTACAATCTGGGTGG | KRT77 | ENSG00000189182 | -0.8324343847892647 | [4,4] | [2,0] | -8 | hSpCas9 | positive selection | 2998268 | 52703388 | 52703411 | 12 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCTGCTCATTGAACTAAACGCGG | KRT77 | ENSG00000189182 | -0.010785466066985909 | [3,3] | [3,2] | 0 | hSpCas9 | positive selection | 2998269 | 52703125 | 52703148 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CTTTGGGGTTGGCAGCACCGGGG | KRT77 | ENSG00000189182 | 0.0715913549830195 | [2,2] | [3,1] | 1 | hSpCas9 | positive selection | 2998270 | 52697722 | 52697745 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.23282429039920471 | [3,3] | [3,1] | -3 | hSpCas9 | positive selection | 2998271 | 52703238 | 52703261 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | AGGAGCCTCTACAATCTGGGTGG | KRT77 | ENSG00000189182 | 0.4618185275227964 | [4,4] | [4,4] | 7 | hSpCas9 | positive selection | 3066126 | 52703388 | 52703411 | 12 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCTGCTCATTGAACTAAACGCGG | KRT77 | ENSG00000189182 | 0.1287674815153712 | [3,3] | [3,1] | 2 | hSpCas9 | positive selection | 3066127 | 52703125 | 52703148 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CTTTGGGGTTGGCAGCACCGGGG | KRT77 | ENSG00000189182 | 0.1406345908255624 | [2,2] | [1,1] | 2 | hSpCas9 | positive selection | 3066128 | 52697722 | 52697745 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.21168659482359486 | [3,3] | [4,1] | 4 | hSpCas9 | positive selection | 3066129 | 52697722 | 52697745 | | - | 24336571 | A375 | resistance to PLX after 7 days | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.025920102083813817 | [10,11] | [11,11] | 1 | hSpCas9 | positive selection | 3123832 | 52697884 | 52697907 | | - | 24336571 | A375 | resistance to PLX after 7 days | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | -0.38150476810358463 | [20,25] | [17,16] | -9 | hSpCas9 | positive selection | 3123833 | 52697722 | 52697745 | | - | 24336571 | A375 | resistance to PLX after 14 days | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.4175515916099869 | [9,16] | [4,3] | -5 | hSpCas9 | positive selection | 3181625 | 52697884 | 52697907 | | - | 24336571 | A375 | resistance to PLX after 14 days | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | -0.3256943943855268 | [17,22] | [5,8] | -4 | hSpCas9 | positive selection | 3181626 | 52697722 | 52697745 | | - | 24336571 | A375 | viability after 7 days | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.5743087846981528 | [17] | [10,11] | -7 | hSpCas9 | negative selection | 3239418 | 52697884 | 52697907 | | - | 24336571 | A375 | viability after 7 days | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.6852412845455413 | [14] | [20,25] | 8 | hSpCas9 | negative selection | 3239419 | 52697722 | 52697745 | | - | 24336571 | A375 | viability after 14 days | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.36705823815450545 | [17] | [9,16] | -4 | hSpCas9 | negative selection | 3297211 | 52697884 | 52697907 | | - | 24336571 | A375 | viability after 14 days | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.5398051309451534 | [14] | [17,22] | 7 | hSpCas9 | negative selection | 3297212 | 52703238 | 52703261 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | AGGAGCCTCTACAATCTGGGTGG | KRT77 | ENSG00000189182 | 0.893421587104008 | [] | [] | 3 | hSpCas9 | negative selection | 3435725 | 52703387 | 52703410 | 12 | + | 26780180 | HT29 | viability (Avana library 4 designs) | CCTGCTCATTGAACTAAACGCGG | KRT77 | ENSG00000189182 | -0.686686492806079 | [] | [] | -8 | hSpCas9 | negative selection | 3435726 | 52703125 | 52703148 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CTTTGGGGTTGGCAGCACCGGGG | KRT77 | ENSG00000189182 | 2.64705088425648 | [] | [] | 8 | hSpCas9 | negative selection | 3435727 | 52697722 | 52697745 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.538043264029119 | [] | [] | 2 | hSpCas9 | negative selection | 3435728 | 52703125 | 52703148 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CTTTGGGGTTGGCAGCACCGGGG | KRT77 | ENSG00000189182 | 1.5638027713577 | [] | [] | 2 | hSpCas9 | negative selection | 3523431 | 52703387 | 52703410 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTGCTCATTGAACTAAACGCGG | KRT77 | ENSG00000189182 | -2.2887052599321 | [] | [] | -3 | hSpCas9 | negative selection | 3523432 | 52703238 | 52703261 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | AGGAGCCTCTACAATCTGGGTGG | KRT77 | ENSG00000189182 | 0.803066905413733 | [] | [] | 1 | hSpCas9 | negative selection | 3523433 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 2.10673879590161 | [] | [] | 3 | hSpCas9 | negative selection | 3523434 | 52703309 | 52703332 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GTTCTGTGTGTTATGCTCGAGGG | KRT77 | ENSG00000189182 | 2.44173295062936 | [] | [] | 3 | hSpCas9 | negative selection | 3523435 | 52703031 | 52703054 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGTCCTTATTGTCCTCCTGGGGG | KRT77 | ENSG00000189182 | 0.738669602650013 | [] | [] | 1 | hSpCas9 | negative selection | 3523436 | 52703125 | 52703148 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | CTTTGGGGTTGGCAGCACCGGGG | KRT77 | ENSG00000189182 | -2.86092162693633 | [] | [] | -5 | hSpCas9 | negative selection | 3632090 | 52703387 | 52703410 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | CCTGCTCATTGAACTAAACGCGG | KRT77 | ENSG00000189182 | -5.07552719199256 | [] | [] | -8 | hSpCas9 | negative selection | 3632091 | 52703238 | 52703261 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | AGGAGCCTCTACAATCTGGGTGG | KRT77 | ENSG00000189182 | 4.70564445623624 | [] | [] | 4 | hSpCas9 | negative selection | 3632092 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -8.5478016609035 | [] | [] | -9 | hSpCas9 | negative selection | 3632093 | 52703309 | 52703332 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GTTCTGTGTGTTATGCTCGAGGG | KRT77 | ENSG00000189182 | -5.49653700753955 | [] | [] | -8 | hSpCas9 | negative selection | 3632094 | 52703031 | 52703054 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GGTCCTTATTGTCCTCCTGGGGG | KRT77 | ENSG00000189182 | 3.59239321267111 | [] | [] | 3 | hSpCas9 | negative selection | 3632095 | 52703125 | 52703148 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CTTTGGGGTTGGCAGCACCGGGG | KRT77 | ENSG00000189182 | 0.06268901949198014 | [3] | [3,3] | 1 | hSpCas9 | positive selection | 3740749 | 52703387 | 52703410 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTGCTCATTGAACTAAACGCGG | KRT77 | ENSG00000189182 | -0.2382306153275522 | [4] | [4,3] | -4 | hSpCas9 | positive selection | 3740750 | 52703238 | 52703261 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | AGGAGCCTCTACAATCTGGGTGG | KRT77 | ENSG00000189182 | -0.333101664527093 | [4] | [5,1] | -5 | hSpCas9 | positive selection | 3740751 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.04102261562333434 | [4] | [4,3] | 0 | hSpCas9 | positive selection | 3740752 | 52703309 | 52703332 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GTTCTGTGTGTTATGCTCGAGGG | KRT77 | ENSG00000189182 | 0.2208611535522977 | [5] | [6,6] | 6 | hSpCas9 | positive selection | 3740753 | 52703031 | 52703054 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGTCCTTATTGTCCTCCTGGGGG | KRT77 | ENSG00000189182 | 0.006875638301077414 | [5] | [4,4] | 0 | hSpCas9 | positive selection | 3740754 | 52703125 | 52703148 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CTTTGGGGTTGGCAGCACCGGGG | KRT77 | ENSG00000189182 | 0.22013639809488608 | [4] | [3,4] | 5 | hSpCas9 | positive selection | 3849356 | 52703387 | 52703410 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTGCTCATTGAACTAAACGCGG | KRT77 | ENSG00000189182 | 0.04755939610874044 | [5] | [5,3] | 1 | hSpCas9 | positive selection | 3849357 | 52703238 | 52703261 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | AGGAGCCTCTACAATCTGGGTGG | KRT77 | ENSG00000189182 | 0.020676747952981724 | [5] | [5,3] | 0 | hSpCas9 | positive selection | 3849358 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.20262495450160137 | [5] | [5,5] | 5 | hSpCas9 | positive selection | 3849359 | 52703309 | 52703332 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GTTCTGTGTGTTATGCTCGAGGG | KRT77 | ENSG00000189182 | 0.20561373172865702 | [6] | [6,5] | 5 | hSpCas9 | positive selection | 3849360 | 52703031 | 52703054 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGTCCTTATTGTCCTCCTGGGGG | KRT77 | ENSG00000189182 | 0.16026250152013147 | [5] | [5,4] | 4 | hSpCas9 | positive selection | 3849361 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.825531590485566 | [] | [] | 3 | hSpCas9 | negative selection | 3955435 | 52697884 | 52697907 | 12 | - | 26780180 | A375 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 1.06599473777097 | [] | [] | 5 | hSpCas9 | negative selection | 3955436 | 52697722 | 52697745 | 12 | - | 26780180 | HT29 | viability (GeCKOv2 library) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.636785234996716 | [] | [] | 2 | hSpCas9 | negative selection | 4063401 | 52697884 | 52697907 | 12 | - | 26780180 | HT29 | viability (GeCKOv2 library) | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 1.19483808478802 | [] | [] | 6 | hSpCas9 | negative selection | 4063402 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.3570867994827985 | [3] | [1,1] | -7 | hSpCas9 | positive selection | 4147802 | 52697884 | 52697907 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiCRISPRv1) | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.18532517166171336 | [4] | [4,2] | 5 | hSpCas9 | positive selection | 4147804 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 1.069270399957594 | [4] | [3,0,1,5] | 7 | hSpCas9 | positive selection | 4211824 | 52697884 | 52697907 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv1 lentiGuide) | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.7795420603807235 | [3] | [1,1,2,3] | 5 | hSpCas9 | positive selection | 4211826 | 52697722 | 52697745 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.11830558306921624 | [1] | [1,0] | -2 | hSpCas9 | positive selection | 4279218 | 52697884 | 52697907 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.16997598767543007 | [3] | [3,2] | 3 | hSpCas9 | positive selection | 4279219 | 52703061 | 52703083 | 12 | - | 27760321 | OCIAML3 | viability | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.48049184008926804 | [637,558] | [530,808] | 6 | hSpCas9 | negative selection | 4413231 | 52703127 | 52703149 | 12 | - | 27760321 | OCIAML3 | viability | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | 0.8636223986268325 | [467,371] | [488,730] | 8 | hSpCas9 | negative selection | 4413232 | 52703272 | 52703294 | 12 | - | 27760321 | OCIAML3 | viability | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -0.44061851570401434 | [224,195] | [74,180] | -4 | hSpCas9 | negative selection | 4413233 | 52703306 | 52703328 | 12 | - | 27760321 | OCIAML3 | viability | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.2812284493639876 | [640,562] | [324,466] | -3 | hSpCas9 | negative selection | 4413234 | 52703061 | 52703083 | 12 | - | 27760321 | OCIAML2 | viability | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.4247421291644752 | [637,558] | [509,830] | 6 | hSpCas9 | negative selection | 4496694 | 52703127 | 52703149 | 12 | - | 27760321 | OCIAML2 | viability | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | 0.20825406406731384 | [467,371] | [349,442] | 2 | hSpCas9 | negative selection | 4496695 | 52703272 | 52703294 | 12 | - | 27760321 | OCIAML2 | viability | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | 0.28872826398640894 | [224,195] | [172,252] | 4 | hSpCas9 | negative selection | 4496696 | 52703306 | 52703328 | 12 | - | 27760321 | OCIAML2 | viability | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.3019142036307503 | [640,562] | [599,597] | 4 | hSpCas9 | negative selection | 4496697 | 52703061 | 52703083 | 12 | - | 27760321 | MV411 | viability | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.41516549858398544 | [637,558] | [674,300] | 3 | hSpCas9 | negative selection | 4580157 | 52703127 | 52703149 | 12 | - | 27760321 | MV411 | viability | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -0.36041331006320265 | [467,371] | [182,261] | -3 | hSpCas9 | negative selection | 4580158 | 52703272 | 52703294 | 12 | - | 27760321 | MV411 | viability | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | 1.0529315305122688 | [224,195] | [428,74] | 7 | hSpCas9 | negative selection | 4580159 | 52703306 | 52703328 | 12 | - | 27760321 | MV411 | viability | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.4359867581906657 | [640,562] | [698,291] | 3 | hSpCas9 | negative selection | 4580160 | 52703061 | 52703083 | 12 | - | 27760321 | HL60 | viability | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.2785136073928147 | [637,558] | [632,547] | 3 | hSpCas9 | negative selection | 4663620 | 52703127 | 52703149 | 12 | - | 27760321 | HL60 | viability | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | 0.23997356826325023 | [467,371] | [392,412] | 3 | hSpCas9 | negative selection | 4663621 | 52703272 | 52703294 | 12 | - | 27760321 | HL60 | viability | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | 0.10720692786369934 | [224,195] | [193,174] | 1 | hSpCas9 | negative selection | 4663622 | 52703306 | 52703328 | 12 | - | 27760321 | HL60 | viability | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.018968760667167572 | [640,562] | [455,540] | 0 | hSpCas9 | negative selection | 4663623 | 52703061 | 52703083 | 12 | - | 27760321 | HT1080 | viability | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.6605122430278391 | [558,435] | [286,341] | 3 | hSpCas9 | negative selection | 4747083 | 52703127 | 52703149 | 12 | - | 27760321 | HT1080 | viability | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -2.127190521635047 | [371,289] | [33,25] | -6 | hSpCas9 | negative selection | 4747084 | 52703272 | 52703294 | 12 | - | 27760321 | HT1080 | viability | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -4.1691464610974815 | [195,152] | [0,6] | -8 | hSpCas9 | negative selection | 4747085 | 52703306 | 52703328 | 12 | - | 27760321 | HT1080 | viability | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 1.4155717973408313 | [562,439] | [279,809] | 7 | hSpCas9 | negative selection | 4747086 | 52703061 | 52703083 | 12 | - | 27760321 | HT29 | viability after 7 days | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.01511763886420009 | [558,435] | [917,575,487] | 0 | hSpCas9 | negative selection | 4830546 | 52703127 | 52703149 | 12 | - | 27760321 | HT29 | viability after 7 days | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | 0.09107235586433228 | [371,289] | [297,489,545] | 1 | hSpCas9 | negative selection | 4830547 | 52703272 | 52703294 | 12 | - | 27760321 | HT29 | viability after 7 days | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | 0.19710620256038247 | [195,152] | [83,387,273] | 3 | hSpCas9 | negative selection | 4830548 | 52703306 | 52703328 | 12 | - | 27760321 | HT29 | viability after 7 days | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.12790311629691337 | [562,439] | [557,649,557] | -2 | hSpCas9 | negative selection | 4830549 | 52703061 | 52703083 | 12 | - | 27760321 | HT29 | viability after 25 days | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.7992376361979617 | [558,435] | [890,1184,885] | 8 | hSpCas9 | negative selection | 4914009 | 52703127 | 52703149 | 12 | - | 27760321 | HT29 | viability after 25 days | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -0.3575502674826271 | [371,289] | [241,269,385] | -4 | hSpCas9 | negative selection | 4914010 | 52703272 | 52703294 | 12 | - | 27760321 | HT29 | viability after 25 days | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -0.6043387553976283 | [195,152] | [103,142,149] | -5 | hSpCas9 | negative selection | 4914011 | 52703306 | 52703328 | 12 | - | 27760321 | HT29 | viability after 25 days | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.27523035846151656 | [562,439] | [399,445,590] | -3 | hSpCas9 | negative selection | 4914012 | 52703061 | 52703083 | 12 | - | 27760321 | HT29 | viability after 22 days | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.5774110688074109 | [558,435] | [779,997,797] | 6 | hSpCas9 | negative selection | 4997472 | 52703127 | 52703149 | 12 | - | 27760321 | HT29 | viability after 22 days | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -0.42450288931455904 | [371,289] | [303,239,310] | -4 | hSpCas9 | negative selection | 4997473 | 52703272 | 52703294 | 12 | - | 27760321 | HT29 | viability after 22 days | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -0.2709587531253199 | [195,152] | [144,206,149] | -3 | hSpCas9 | negative selection | 4997474 | 52703306 | 52703328 | 12 | - | 27760321 | HT29 | viability after 22 days | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.07853110259460827 | [562,439] | [552,559,533] | -1 | hSpCas9 | negative selection | 4997475 | 52703061 | 52703083 | 12 | - | 27760321 | HT29 | viability after 19 days | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.22141088925954466 | [558,435] | [809,855,350] | 2 | hSpCas9 | negative selection | 5080935 | 52703127 | 52703149 | 12 | - | 27760321 | HT29 | viability after 19 days | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -0.7644439964016227 | [371,289] | [295,290,93] | -6 | hSpCas9 | negative selection | 5080936 | 52703272 | 52703294 | 12 | - | 27760321 | HT29 | viability after 19 days | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -0.31793968627547886 | [195,152] | [101,74,291] | -3 | hSpCas9 | negative selection | 5080937 | 52703306 | 52703328 | 12 | - | 27760321 | HT29 | viability after 19 days | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.8361752276834896 | [562,439] | [490,157,331] | -6 | hSpCas9 | negative selection | 5080938 | 52703061 | 52703083 | 12 | - | 27760321 | HT29 | viability after 16 days | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.2468222582590308 | [558,435] | [557,603,810] | 2 | hSpCas9 | negative selection | 5164398 | 52703127 | 52703149 | 12 | - | 27760321 | HT29 | viability after 16 days | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -0.07593143418166381 | [371,289] | [424,306,329] | -1 | hSpCas9 | negative selection | 5164399 | 52703272 | 52703294 | 12 | - | 27760321 | HT29 | viability after 16 days | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -0.9861079118646316 | [195,152] | [79,56,157] | -7 | hSpCas9 | negative selection | 5164400 | 52703306 | 52703328 | 12 | - | 27760321 | HT29 | viability after 16 days | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.38710500974462503 | [562,439] | [345,478,452] | -4 | hSpCas9 | negative selection | 5164401 | 52703061 | 52703083 | 12 | - | 27760321 | HT29 | viability after 13 days | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.24528432569097203 | [558,435] | [615,644,784] | 3 | hSpCas9 | negative selection | 5247861 | 52703127 | 52703149 | 12 | - | 27760321 | HT29 | viability after 13 days | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | 0.006330664266166047 | [371,289] | [469,220,460] | 0 | hSpCas9 | negative selection | 5247862 | 52703272 | 52703294 | 12 | - | 27760321 | HT29 | viability after 13 days | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -0.11577596300215709 | [195,152] | [194,85,273] | -1 | hSpCas9 | negative selection | 5247863 | 52703306 | 52703328 | 12 | - | 27760321 | HT29 | viability after 13 days | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.21945468850749306 | [562,439] | [617,468,416] | -3 | hSpCas9 | negative selection | 5247864 | 52703061 | 52703083 | 12 | - | 27760321 | HT29 | viability after 10 days | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 0.12876184398304757 | [558,435] | [559,907,577] | 1 | hSpCas9 | negative selection | 5331324 | 52703127 | 52703149 | 12 | - | 27760321 | HT29 | viability after 10 days | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -0.3108087378498955 | [371,289] | [413,308,276] | -4 | hSpCas9 | negative selection | 5331325 | 52703272 | 52703294 | 12 | - | 27760321 | HT29 | viability after 10 days | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -0.42205639163961695 | [195,152] | [138,216,133] | -5 | hSpCas9 | negative selection | 5331326 | 52703306 | 52703328 | 12 | - | 27760321 | HT29 | viability after 10 days | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.6154279365312927 | [562,439] | [355,448,421] | -6 | hSpCas9 | negative selection | 5331327 | 52703061 | 52703083 | 12 | - | 27760321 | MOLM13 | viability | GGACTAGCAATTTTGGGCTTGG | KRT77 | ENSG00000189182 | 1.307544177916196 | [637,558] | [974,713] | 8 | hSpCas9 | negative selection | 5414787 | 52703127 | 52703149 | 12 | - | 27760321 | MOLM13 | viability | GCTTTGGGGTTGGCAGCACCGG | KRT77 | ENSG00000189182 | -1.4277141992655975 | [467,371] | [133,47] | -7 | hSpCas9 | negative selection | 5414788 | 52703272 | 52703294 | 12 | - | 27760321 | MOLM13 | viability | GGATATGGGATCCATGGAAGGG | KRT77 | ENSG00000189182 | -1.080593320059662 | [224,195] | [48,61] | -6 | hSpCas9 | negative selection | 5414789 | 52703306 | 52703328 | 12 | - | 27760321 | MOLM13 | viability | TGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.3564108863054116 | [640,562] | [267,261] | -2 | hSpCas9 | negative selection | 5414790 | 52703277 | 52703300 | 12 | - | 27661255 | K562 | viability | GGTGGTGGATATGGGATCCATGG | KRT77 | ENSG00000189182 | 0.2570523221749308 | [930,1302] | [1216,925] | 8 | dCas9-KRAB | negative selection | 5489361 | 52697722 | 52697745 | 12 | - | 27260156 | BXPC3 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.13771871443685835 | [137] | [146,147,183,156] | 3 | hSpCas9 | negative selection | 5551678 | 52697884 | 52697907 | 12 | - | 27260156 | BXPC3 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.10926829815450612 | [594] | [600,547,904,640] | 2 | hSpCas9 | negative selection | 5551679 | 52697722 | 52697745 | 12 | - | 27260156 | A673 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.18321095249937835 | [137] | [210,154,194,194] | 4 | hSpCas9 | negative selection | 5672929 | 52697884 | 52697907 | 12 | - | 27260156 | A673 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.07148030231487923 | [594] | [847,705,667,794] | 1 | hSpCas9 | negative selection | 5672930 | 52697722 | 52697745 | 12 | - | 27260156 | A375 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.11279248657754959 | [137] | [109,159,267,157] | 1 | hSpCas9 | negative selection | 5794180 | 52697884 | 52697907 | 12 | - | 27260156 | A375 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.2847390278772864 | [594] | [613,1009,1089,706] | 4 | hSpCas9 | negative selection | 5794181 | 52697722 | 52697745 | 12 | - | 27260156 | COLO741 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.3936161847717192 | [137] | [261,162,268] | 7 | hSpCas9 | negative selection | 5915431 | 52697884 | 52697907 | 12 | - | 27260156 | COLO741 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | -0.17637161888412917 | [594] | [605,798,610] | -4 | hSpCas9 | negative selection | 5915432 | 52697722 | 52697745 | 12 | - | 27260156 | CAL120 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.13209497425463246 | [137] | [307,168,106] | 2 | hSpCas9 | negative selection | 6036682 | 52697884 | 52697907 | 12 | - | 27260156 | CAL120 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.17098252552753263 | [594] | [817,788,889] | 2 | hSpCas9 | negative selection | 6036683 | 52697722 | 52697745 | 12 | - | 27260156 | CADOES1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.31947824769717315 | [137] | [101,108,82,117] | -5 | hSpCas9 | negative selection | 6157933 | 52697884 | 52697907 | 12 | - | 27260156 | CADOES1 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.3142342951602382 | [594] | [461,572,811,913] | 5 | hSpCas9 | negative selection | 6157934 | 52697722 | 52697745 | 12 | - | 27260156 | EWS502 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.04065582177195126 | [137] | [64,141,123,253] | 0 | hSpCas9 | negative selection | 6279184 | 52697884 | 52697907 | 12 | - | 27260156 | EWS502 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.2888782088949183 | [594] | [794,766,618,899] | 5 | hSpCas9 | negative selection | 6279185 | 52697722 | 52697745 | 12 | - | 27260156 | EW8 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.447850970755294 | [137] | [98,136,143,224] | 7 | hSpCas9 | negative selection | 6400435 | 52697884 | 52697907 | 12 | - | 27260156 | EW8 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.0537114876574572 | [594] | [535,511,455,507] | 1 | hSpCas9 | negative selection | 6400436 | 52697722 | 52697745 | 12 | - | 27260156 | CORL105 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.4407648219721456 | [137] | [205,206,320,158] | 7 | hSpCas9 | negative selection | 6521686 | 52697884 | 52697907 | 12 | - | 27260156 | CORL105 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.3079938237142564 | [594] | [963,681,982,845] | 6 | hSpCas9 | negative selection | 6521687 | 52697722 | 52697745 | 12 | - | 27260156 | HS294T | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 1.3316023784357016 | [137] | [139,151,176,52] | 9 | hSpCas9 | negative selection | 6642937 | 52697884 | 52697907 | 12 | - | 27260156 | HS294T | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.12094490145376369 | [594] | [157,331,190,339] | 1 | hSpCas9 | negative selection | 6642938 | 52697722 | 52697745 | 12 | - | 27260156 | HCC44 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.1721377626185614 | [137] | [225,85,137,118] | -3 | hSpCas9 | negative selection | 6764188 | 52697884 | 52697907 | 12 | - | 27260156 | HCC44 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.13869262064278587 | [594] | [913,668,735,665] | 2 | hSpCas9 | negative selection | 6764189 | 52697722 | 52697745 | 12 | - | 27260156 | G402 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.10565669001330114 | [137] | [348,183,75,50] | -1 | hSpCas9 | negative selection | 6885439 | 52697884 | 52697907 | 12 | - | 27260156 | G402 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.16094483343744098 | [594] | [725,839,771,890] | 2 | hSpCas9 | negative selection | 6885440 | 52697722 | 52697745 | 12 | - | 27260156 | L33 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.2747219451203027 | [137] | [160,59,92,211] | 6 | hSpCas9 | negative selection | 7006690 | 52697884 | 52697907 | 12 | - | 27260156 | L33 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.12962941404362316 | [594] | [725,244,377,675] | 3 | hSpCas9 | negative selection | 7006691 | 52697722 | 52697745 | 12 | - | 27260156 | K562 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 1.0754563688478056 | [137] | [123,110,240,506] | 9 | hSpCas9 | negative selection | 7127941 | 52697884 | 52697907 | 12 | - | 27260156 | K562 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.4520826788347874 | [594] | [822,571,772,718] | 6 | hSpCas9 | negative selection | 7127942 | 52697722 | 52697745 | 12 | - | 27260156 | HT29 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.24749348086105272 | [137] | [177,141,254,211] | 5 | hSpCas9 | negative selection | 7249192 | 52697884 | 52697907 | 12 | - | 27260156 | HT29 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.2947852086947465 | [594] | [951,1062,645,899] | 6 | hSpCas9 | negative selection | 7249193 | 52697722 | 52697745 | 12 | - | 27260156 | MHHES1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.02939654154366922 | [137] | [157,77,192,186] | 0 | hSpCas9 | negative selection | 7370443 | 52697884 | 52697907 | 12 | - | 27260156 | MHHES1 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.3751611274735788 | [594] | [1084,1026,873,580] | 6 | hSpCas9 | negative selection | 7370444 | 52697722 | 52697745 | 12 | - | 27260156 | MEWO | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.07634884561925115 | [137] | [196,75,108] | -2 | hSpCas9 | negative selection | 7491694 | 52697884 | 52697907 | 12 | - | 27260156 | MEWO | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.030714939897409976 | [594] | [537,537,623] | 0 | hSpCas9 | negative selection | 7491695 | 52697722 | 52697745 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.26945730792595257 | [137] | [91,118,272,139] | 4 | hSpCas9 | negative selection | 7612945 | 52697884 | 52697907 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.2114575612305714 | [594] | [578,595,754,587] | 3 | hSpCas9 | negative selection | 7612946 | 52697722 | 52697745 | 12 | - | 27260156 | PANC0327 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.36975133383831116 | [137] | [134,77,120,50] | -5 | hSpCas9 | negative selection | 7734196 | 52697884 | 52697907 | 12 | - | 27260156 | PANC0327 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.30069412455299044 | [594] | [797,610,571,639] | 4 | hSpCas9 | negative selection | 7734197 | 52697722 | 52697745 | 12 | - | 27260156 | NCIH2009 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.32640467912117965 | [137] | [248,202,274] | 4 | hSpCas9 | negative selection | 7855447 | 52697884 | 52697907 | 12 | - | 27260156 | NCIH2009 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.4210341647849512 | [594] | [1278,1112,977] | 6 | hSpCas9 | negative selection | 7855448 | 52697722 | 52697745 | 12 | - | 27260156 | NCIH1373 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.6752277497617034 | [137] | [26,102,141,26] | -6 | hSpCas9 | negative selection | 7976698 | 52697884 | 52697907 | 12 | - | 27260156 | NCIH1373 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.5435737081435796 | [594] | [1240,743,391,426] | 5 | hSpCas9 | negative selection | 7976699 | 52697722 | 52697745 | 12 | - | 27260156 | PATU8902 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.4604825130435799 | [137] | [332,160,82,559] | 5 | hSpCas9 | negative selection | 8097949 | 52697884 | 52697907 | 12 | - | 27260156 | PATU8902 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | -0.6357437379651262 | [594] | [636,459,501,536] | -6 | hSpCas9 | negative selection | 8097950 | 52697722 | 52697745 | 12 | - | 27260156 | PANC1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.580642737355523 | [137] | [147,249,169,156] | 8 | hSpCas9 | negative selection | 8219200 | 52697884 | 52697907 | 12 | - | 27260156 | PANC1 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.1778768447162043 | [594] | [477,980,455,486] | 3 | hSpCas9 | negative selection | 8219201 | 52697722 | 52697745 | 12 | - | 27260156 | PANC0813 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.6433419820108213 | [137] | [311,361,193,154] | 8 | hSpCas9 | negative selection | 8340451 | 52697884 | 52697907 | 12 | - | 27260156 | PANC0813 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.40406130185102157 | [594] | [1019,1102,860,732] | 6 | hSpCas9 | negative selection | 8340452 | 52697722 | 52697745 | 12 | - | 27260156 | RDES | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.3477997846772567 | [137] | [140,79,136,139] | -5 | hSpCas9 | negative selection | 8461702 | 52697884 | 52697907 | 12 | - | 27260156 | RDES | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.07529998209403432 | [594] | [666,674,645,914] | 1 | hSpCas9 | negative selection | 8461703 | 52697722 | 52697745 | 12 | - | 27260156 | PC3 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.33631187354641146 | [137] | [113,239,232,132] | 7 | hSpCas9 | negative selection | 8582953 | 52697884 | 52697907 | 12 | - | 27260156 | PC3 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | -0.15701536058502313 | [594] | [425,324,891,623] | -4 | hSpCas9 | negative selection | 8582954 | 52697722 | 52697745 | 12 | - | 27260156 | PATU8988T | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.2602264463930952 | [137] | [217,249,32,146] | 4 | hSpCas9 | negative selection | 8704204 | 52697884 | 52697907 | 12 | - | 27260156 | PATU8988T | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.29580143162694267 | [594] | [544,1106,723,464] | 5 | hSpCas9 | negative selection | 8704205 | 52697722 | 52697745 | 12 | - | 27260156 | T47D | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.19322891256707297 | [137] | [172,113,155,120] | -4 | hSpCas9 | negative selection | 8825455 | 52697884 | 52697907 | 12 | - | 27260156 | T47D | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.07417778739513542 | [594] | [665,605,825,832] | 1 | hSpCas9 | negative selection | 8825456 | 52697722 | 52697745 | 12 | - | 27260156 | SU8686 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.11903444072343805 | [137] | [94,118,184,106] | -2 | hSpCas9 | negative selection | 8946706 | 52697884 | 52697907 | 12 | - | 27260156 | SU8686 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.22553830198289776 | [594] | [587,602,606,1031] | 4 | hSpCas9 | negative selection | 8946707 | 52697722 | 52697745 | 12 | - | 27260156 | SKES1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.3039092075238572 | [137] | [141,146,72,93] | -6 | hSpCas9 | negative selection | 9067957 | 52697884 | 52697907 | 12 | - | 27260156 | SKES1 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.14062077984508176 | [594] | [865,687,546,555] | 3 | hSpCas9 | negative selection | 9067958 | 52697722 | 52697745 | 12 | - | 27260156 | TOV112D | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.25415830320896426 | [137] | [159,85,145,244] | 5 | hSpCas9 | negative selection | 9189208 | 52697884 | 52697907 | 12 | - | 27260156 | TOV112D | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.12310044128929598 | [594] | [785,879,517,483] | 2 | hSpCas9 | negative selection | 9189209 | 52697722 | 52697745 | 12 | - | 27260156 | TC71 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.08441383340844966 | [137] | [98,156,151,224] | 2 | hSpCas9 | negative selection | 9310459 | 52697884 | 52697907 | 12 | - | 27260156 | TC71 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.04019851053138118 | [594] | [640,709,645,624] | 1 | hSpCas9 | negative selection | 9310460 | 52697722 | 52697745 | 12 | - | 27260156 | TC32 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.06597740879256397 | [137] | [124,83,144,207] | 1 | hSpCas9 | negative selection | 9431710 | 52697884 | 52697907 | 12 | - | 27260156 | TC32 | viability | TTGCTCTTAGGTGCGATTCCTGG | KRT77 | ENSG00000189182 | 0.13763030266549514 | [594] | [625,550,665,608] | 2 | hSpCas9 | negative selection | 9431711 | 52691314 | 52691337 | 12 | - | 27869803 | HPAFII | viability after 27 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.5843282654091921 | [78] | [22,94,NaN] | 5 | hSpCas9 | negative selection | 9547283 | 52697806 | 52697829 | 12 | - | 27869803 | HPAFII | viability after 27 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.4716171322422509 | [778] | [778,391,NaN] | 4 | hSpCas9 | negative selection | 9547284 | 52698194 | 52698217 | 12 | - | 27869803 | HPAFII | viability after 27 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.311192949322299 | [153] | [261,149,NaN] | 9 | hSpCas9 | negative selection | 9547285 | 52703306 | 52703329 | 12 | - | 27869803 | HPAFII | viability after 27 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.32385040701839085 | [414] | [271,273,NaN] | 2 | hSpCas9 | negative selection | 9547286 | 52691314 | 52691337 | 12 | - | 27869803 | HPAFII | viability after 15 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -0.3812755793065268 | [78] | [87,50,NaN] | -4 | hSpCas9 | negative selection | 9629732 | 52697806 | 52697829 | 12 | - | 27869803 | HPAFII | viability after 15 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.2882717752891357 | [778] | [1757,564,NaN] | 3 | hSpCas9 | negative selection | 9629733 | 52698194 | 52698217 | 12 | - | 27869803 | HPAFII | viability after 15 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.099190138904538 | [153] | [451,293,NaN] | 9 | hSpCas9 | negative selection | 9629734 | 52703306 | 52703329 | 12 | - | 27869803 | HPAFII | viability after 15 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | -0.2455803509881796 | [414] | [390,366,NaN] | -3 | hSpCas9 | negative selection | 9629735 | 52691314 | 52691337 | 12 | - | 27869803 | ASPC1 | viability after 36 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 1.3124115166895327 | [188] | [237,66,186] | 9 | hSpCas9 | negative selection | 9712181 | 52697806 | 52697829 | 12 | - | 27869803 | ASPC1 | viability after 36 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | -0.091435399749761 | [1852] | [614,430,734] | -1 | hSpCas9 | negative selection | 9712182 | 52698194 | 52698217 | 12 | - | 27869803 | ASPC1 | viability after 36 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.5535218516472475 | [370] | [334,245,41] | 5 | hSpCas9 | negative selection | 9712183 | 52703306 | 52703329 | 12 | - | 27869803 | ASPC1 | viability after 36 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.1696172921491485 | [854] | [549,274,229] | 1 | hSpCas9 | negative selection | 9712184 | 52691314 | 52691337 | 12 | - | 27869803 | PATU8988S | viability after 35 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.15848587241092793 | [248] | [80,142,NaN] | 1 | hSpCas9 | negative selection | 9794630 | 52697806 | 52697829 | 12 | - | 27869803 | PATU8988S | viability after 35 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | -0.1336652577862163 | [1510] | [644,463,NaN] | -1 | hSpCas9 | negative selection | 9794631 | 52698194 | 52698217 | 12 | - | 27869803 | PATU8988S | viability after 35 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.34261427220170654 | [417] | [202,223,NaN] | 4 | hSpCas9 | negative selection | 9794632 | 52703306 | 52703329 | 12 | - | 27869803 | PATU8988S | viability after 35 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.6549589127565641 | [795] | [631,376,NaN] | 7 | hSpCas9 | negative selection | 9794633 | 52691314 | 52691337 | 12 | - | 27869803 | PATU8988S | viability after 31 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | -0.3218250345167464 | [248] | [56,107,NaN] | -4 | hSpCas9 | negative selection | 9877079 | 52697806 | 52697829 | 12 | - | 27869803 | PATU8988S | viability after 31 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | -0.1423332602998022 | [1510] | [632,434,NaN] | -2 | hSpCas9 | negative selection | 9877080 | 52698194 | 52698217 | 12 | - | 27869803 | PATU8988S | viability after 31 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 0.652905602054834 | [417] | [203,335,NaN] | 7 | hSpCas9 | negative selection | 9877081 | 52703306 | 52703329 | 12 | - | 27869803 | PATU8988S | viability after 31 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.4772787669380153 | [795] | [330,582,NaN] | 6 | hSpCas9 | negative selection | 9877082 | 52691314 | 52691337 | 12 | - | 27869803 | HPAFII | viability after 35 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.3214795500297607 | [78] | [1,103,NaN] | 2 | hSpCas9 | negative selection | 9959528 | 52697806 | 52697829 | 12 | - | 27869803 | HPAFII | viability after 35 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.3022074511455599 | [778] | [664,284,NaN] | 2 | hSpCas9 | negative selection | 9959529 | 52698194 | 52698217 | 12 | - | 27869803 | HPAFII | viability after 35 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.820951770268558 | [153] | [353,186,NaN] | 9 | hSpCas9 | negative selection | 9959530 | 52703306 | 52703329 | 12 | - | 27869803 | HPAFII | viability after 35 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.37455318905452006 | [414] | [190,363,NaN] | 2 | hSpCas9 | negative selection | 9959531 | 52691314 | 52691337 | 12 | - | 27869803 | HPAFII | viability after 31 days | AAGAAGCTACCGCGGAGGCGGGG | KRT77 | ENSG00000189182 | 0.41258277940930865 | [78] | [36,82,NaN] | 3 | hSpCas9 | negative selection | 10041977 | 52697806 | 52697829 | 12 | - | 27869803 | HPAFII | viability after 31 days | CTCAACTGGAACCAACAACCTGG | KRT77 | ENSG00000189182 | 0.40931019206316965 | [778] | [783,358,NaN] | 3 | hSpCas9 | negative selection | 10041978 | 52698194 | 52698217 | 12 | - | 27869803 | HPAFII | viability after 31 days | ACCATTTCCTTACGTTGGCATGG | KRT77 | ENSG00000189182 | 1.407362582575411 | [153] | [312,137,NaN] | 9 | hSpCas9 | negative selection | 10041979 | 52703306 | 52703329 | 12 | - | 27869803 | HPAFII | viability after 31 days | CTGTGTGTTATGCTCGAGGGAGG | KRT77 | ENSG00000189182 | 0.29320909048370314 | [414] | [215,360,NaN] | 2 | hSpCas9 | negative selection | 10041980 | 52697722 | 52697745 | 12 | - | 28162770 | P31FUJ | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.37600703826114534 | [39] | [60] | 4 | hSpCas9 | negative selection | 10181657 | 52692566 | 52692589 | 12 | + | 28162770 | P31FUJ | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.24214550327725548 | [453] | [630] | 2 | hSpCas9 | negative selection | 10181658 | 52692551 | 52692574 | 12 | - | 28162770 | P31FUJ | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.5253091986233763 | [148] | [251] | 6 | hSpCas9 | negative selection | 10181659 | 52703271 | 52703294 | 12 | - | 28162770 | P31FUJ | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.10519425910063751 | [124] | [157] | 1 | hSpCas9 | negative selection | 10181660 | 52702975 | 52702998 | 12 | - | 28162770 | P31FUJ | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | -0.1542688018676892 | [285] | [301] | -1 | hSpCas9 | negative selection | 10181661 | 52697768 | 52697791 | 12 | - | 28162770 | P31FUJ | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | -0.7771227206381888 | [174] | [119] | -6 | hSpCas9 | negative selection | 10181662 | 52697722 | 52697745 | 12 | - | 28162770 | TF1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | NaN | [NaN] | [5] | 1 | hSpCas9 | negative selection | 10351023 | 52692566 | 52692589 | 12 | + | 28162770 | TF1 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | NaN | [NaN] | [310] | 1 | hSpCas9 | negative selection | 10351024 | 52692551 | 52692574 | 12 | - | 28162770 | TF1 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | NaN | [NaN] | [126] | 1 | hSpCas9 | negative selection | 10351025 | 52703271 | 52703294 | 12 | - | 28162770 | TF1 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | NaN | [NaN] | [143] | 1 | hSpCas9 | negative selection | 10351026 | 52702975 | 52702998 | 12 | - | 28162770 | TF1 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | NaN | [NaN] | [209] | 1 | hSpCas9 | negative selection | 10351027 | 52697768 | 52697791 | 12 | - | 28162770 | TF1 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | NaN | [NaN] | [150] | 1 | hSpCas9 | negative selection | 10351028 | 52697722 | 52697745 | 12 | - | 28162770 | SKM1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.3625700793847084 | [7] | [10] | -3 | hSpCas9 | negative selection | 10520389 | 52692566 | 52692589 | 12 | + | 28162770 | SKM1 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.33996578164138747 | [100] | [225] | 3 | hSpCas9 | negative selection | 10520390 | 52692551 | 52692574 | 12 | - | 28162770 | SKM1 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.8036027871964966 | [34] | [107] | 7 | hSpCas9 | negative selection | 10520391 | 52703271 | 52703294 | 12 | - | 28162770 | SKM1 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.048715285033028244 | [34] | [63] | 0 | hSpCas9 | negative selection | 10520392 | 52702975 | 52702998 | 12 | - | 28162770 | SKM1 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 1.1085334823148947 | [116] | [445] | 8 | hSpCas9 | negative selection | 10520393 | 52697768 | 52697791 | 12 | - | 28162770 | SKM1 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 0.6973724610715738 | [44] | [128] | 6 | hSpCas9 | negative selection | 10520394 | 52697722 | 52697745 | 12 | - | 28162770 | SKM1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.3625700793847084 | [7] | [10] | -3 | hSpCas9 | negative selection | 10689755 | 52692566 | 52692589 | 12 | + | 28162770 | SKM1 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.33996578164138747 | [100] | [225] | 3 | hSpCas9 | negative selection | 10689756 | 52692551 | 52692574 | 12 | - | 28162770 | SKM1 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.8036027871964966 | [34] | [107] | 7 | hSpCas9 | negative selection | 10689757 | 52703271 | 52703294 | 12 | - | 28162770 | SKM1 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.048715285033028244 | [34] | [63] | 0 | hSpCas9 | negative selection | 10689758 | 52702975 | 52702998 | 12 | - | 28162770 | SKM1 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 1.1085334823148947 | [116] | [445] | 8 | hSpCas9 | negative selection | 10689759 | 52697768 | 52697791 | 12 | - | 28162770 | SKM1 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 0.6973724610715738 | [44] | [128] | 6 | hSpCas9 | negative selection | 10689760 | 52697722 | 52697745 | 12 | - | 28162770 | PL21 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.4158683055447572 | [30] | [17] | 3 | hSpCas9 | negative selection | 10859121 | 52692566 | 52692589 | 12 | + | 28162770 | PL21 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 1.297262081387425 | [358] | [383] | 9 | hSpCas9 | negative selection | 10859122 | 52692551 | 52692574 | 12 | - | 28162770 | PL21 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | -0.03335051573045841 | [173] | [73] | 0 | hSpCas9 | negative selection | 10859123 | 52703271 | 52703294 | 12 | - | 28162770 | PL21 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.8235762630251122 | [147] | [113] | 7 | hSpCas9 | negative selection | 10859124 | 52702975 | 52702998 | 12 | - | 28162770 | PL21 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.3642155402349452 | [356] | [199] | 3 | hSpCas9 | negative selection | 10859125 | 52697768 | 52697791 | 12 | - | 28162770 | PL21 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | -0.2875256848769211 | [128] | [45] | -2 | hSpCas9 | negative selection | 10859126 | 52697722 | 52697745 | 12 | - | 28162770 | P31FUJ | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.37600703826114534 | [39] | [60] | 4 | hSpCas9 | negative selection | 11028487 | 52692566 | 52692589 | 12 | + | 28162770 | P31FUJ | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.24214550327725548 | [453] | [630] | 2 | hSpCas9 | negative selection | 11028488 | 52692551 | 52692574 | 12 | - | 28162770 | P31FUJ | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.5253091986233763 | [148] | [251] | 6 | hSpCas9 | negative selection | 11028489 | 52703271 | 52703294 | 12 | - | 28162770 | P31FUJ | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.10519425910063751 | [124] | [157] | 1 | hSpCas9 | negative selection | 11028490 | 52702975 | 52702998 | 12 | - | 28162770 | P31FUJ | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | -0.1542688018676892 | [285] | [301] | -1 | hSpCas9 | negative selection | 11028491 | 52697768 | 52697791 | 12 | - | 28162770 | P31FUJ | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | -0.7771227206381888 | [174] | [119] | -6 | hSpCas9 | negative selection | 11028492 | 52697722 | 52697745 | 12 | - | 28162770 | OCIAML5 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.4828327611982779 | [23] | [30] | -3 | hSpCas9 | negative selection | 11197853 | 52692566 | 52692589 | 12 | + | 28162770 | OCIAML5 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.7505258238789507 | [243] | [740] | 6 | hSpCas9 | negative selection | 11197854 | 52692551 | 52692574 | 12 | - | 28162770 | OCIAML5 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.36496266570535807 | [76] | [178] | 3 | hSpCas9 | negative selection | 11197855 | 52703271 | 52703294 | 12 | - | 28162770 | OCIAML5 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.6904606635367624 | [45] | [133] | 6 | hSpCas9 | negative selection | 11197856 | 52702975 | 52702998 | 12 | - | 28162770 | OCIAML5 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 1.1868924582557059 | [136] | [562] | 8 | hSpCas9 | negative selection | 11197857 | 52697768 | 52697791 | 12 | - | 28162770 | OCIAML5 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 1.2136576113588395 | [58] | [246] | 9 | hSpCas9 | negative selection | 11197858 | 52697722 | 52697745 | 12 | - | 28162770 | EOL1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 2.37653640702227 | [52] | [144] | 9 | hSpCas9 | negative selection | 11367219 | 52692566 | 52692589 | 12 | + | 28162770 | EOL1 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.4322045461242421 | [459] | [326] | 4 | hSpCas9 | negative selection | 11367220 | 52692551 | 52692574 | 12 | - | 28162770 | EOL1 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | -1.2064758790553858 | [310] | [70] | -7 | hSpCas9 | negative selection | 11367221 | 52703271 | 52703294 | 12 | - | 28162770 | EOL1 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 1.6384080054739485 | [213] | [350] | 9 | hSpCas9 | negative selection | 11367222 | 52702975 | 52702998 | 12 | - | 28162770 | EOL1 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.8590657684880703 | [630] | [602] | 7 | hSpCas9 | negative selection | 11367223 | 52697768 | 52697791 | 12 | - | 28162770 | EOL1 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 1.4267460718932572 | [280] | [397] | 9 | hSpCas9 | negative selection | 11367224 | 52697722 | 52697745 | 12 | - | 28162770 | MOLM13 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.8051291128618367 | [28] | [11] | -4 | hSpCas9 | negative selection | 11536585 | 52692566 | 52692589 | 12 | + | 28162770 | MOLM13 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 1.1459612866572164 | [489] | [783] | 8 | hSpCas9 | negative selection | 11536586 | 52692551 | 52692574 | 12 | - | 28162770 | MOLM13 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | -0.6101131304566942 | [265] | [125] | -4 | hSpCas9 | negative selection | 11536587 | 52703271 | 52703294 | 12 | - | 28162770 | MOLM13 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.21635061454861443 | [174] | [146] | 1 | hSpCas9 | negative selection | 11536588 | 52702975 | 52702998 | 12 | - | 28162770 | MOLM13 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.27926550104902703 | [562] | [493] | 2 | hSpCas9 | negative selection | 11536589 | 52697768 | 52697791 | 12 | - | 28162770 | MOLM13 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 0.21723870016661737 | [231] | [194] | 1 | hSpCas9 | negative selection | 11536590 | 52697722 | 52697745 | 12 | - | 28162770 | HEL | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 0.22770133272151316 | [27] | [20] | 1 | hSpCas9 | negative selection | 11705951 | 52692566 | 52692589 | 12 | + | 28162770 | HEL | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | -0.13109205591771134 | [435] | [254] | -1 | hSpCas9 | negative selection | 11705952 | 52692551 | 52692574 | 12 | - | 28162770 | HEL | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | -0.014659504847530758 | [193] | [122] | 0 | hSpCas9 | negative selection | 11705953 | 52703271 | 52703294 | 12 | - | 28162770 | HEL | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | -0.03216579403359776 | [181] | [113] | 0 | hSpCas9 | negative selection | 11705954 | 52702975 | 52702998 | 12 | - | 28162770 | HEL | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.7040259527845025 | [529] | [552] | 6 | hSpCas9 | negative selection | 11705955 | 52697768 | 52697791 | 12 | - | 28162770 | HEL | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 0.16663980698523437 | [184] | [132] | 1 | hSpCas9 | negative selection | 11705956 | 52697722 | 52697745 | 12 | - | 28162770 | MV411 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -0.46876948321663336 | [22] | [13] | -3 | hSpCas9 | negative selection | 11875317 | 52692566 | 52692589 | 12 | + | 28162770 | MV411 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.05416206206308216 | [326] | [285] | 0 | hSpCas9 | negative selection | 11875318 | 52692551 | 52692574 | 12 | - | 28162770 | MV411 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.23336236557105244 | [205] | [203] | 2 | hSpCas9 | negative selection | 11875319 | 52703271 | 52703294 | 12 | - | 28162770 | MV411 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 1.4066361456320293 | [89] | [200] | 9 | hSpCas9 | negative selection | 11875320 | 52702975 | 52702998 | 12 | - | 28162770 | MV411 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 1.0291210652381824 | [323] | [556] | 8 | hSpCas9 | negative selection | 11875321 | 52697768 | 52697791 | 12 | - | 28162770 | MV411 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | -0.15619518522381906 | [167] | [126] | -1 | hSpCas9 | negative selection | 11875322 | 52697722 | 52697745 | 12 | - | 28162770 | MONOMAC1 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | -1.8850928407448135 | [28] | [8] | -8 | hSpCas9 | negative selection | 12044683 | 52692566 | 52692589 | 12 | + | 28162770 | MONOMAC1 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.08101974939189316 | [206] | [250] | 0 | hSpCas9 | negative selection | 12044684 | 52692551 | 52692574 | 12 | - | 28162770 | MONOMAC1 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.5805707316039985 | [104] | [179] | 5 | hSpCas9 | negative selection | 12044685 | 52703271 | 52703294 | 12 | - | 28162770 | MONOMAC1 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 0.5744859691430211 | [98] | [168] | 5 | hSpCas9 | negative selection | 12044686 | 52702975 | 52702998 | 12 | - | 28162770 | MONOMAC1 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.3469372422107636 | [237] | [346] | 3 | hSpCas9 | negative selection | 12044687 | 52697768 | 52697791 | 12 | - | 28162770 | MONOMAC1 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 1.84347831267916 | [78] | [324] | 9 | hSpCas9 | negative selection | 12044688 | 52697722 | 52697745 | 12 | - | 28162770 | OCIAML2 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 1.4038392926739798 | [2] | [43] | 9 | hSpCas9 | negative selection | 12214049 | 52692566 | 52692589 | 12 | + | 28162770 | OCIAML2 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.2577519227033498 | [58] | [390] | 2 | hSpCas9 | negative selection | 12214050 | 52692551 | 52692574 | 12 | - | 28162770 | OCIAML2 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | -0.3399261335975675 | [28] | [126] | -3 | hSpCas9 | negative selection | 12214051 | 52703271 | 52703294 | 12 | - | 28162770 | OCIAML2 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | 1.0753385438631313 | [24] | [291] | 8 | hSpCas9 | negative selection | 12214052 | 52702975 | 52702998 | 12 | - | 28162770 | OCIAML2 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.6640197014526207 | [68] | [605] | 6 | hSpCas9 | negative selection | 12214053 | 52697768 | 52697791 | 12 | - | 28162770 | OCIAML2 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 1.0826238157516568 | [22] | [269] | 8 | hSpCas9 | negative selection | 12214054 | 52697722 | 52697745 | 12 | - | 28162770 | OCIAML3 | viability | GCAGATGCGCCAGAACGCGGAGG | KRT77 | ENSG00000189182 | 1.821029858954681 | [5] | [63] | 9 | hSpCas9 | negative selection | 12383415 | 52692566 | 52692589 | 12 | + | 28162770 | OCIAML3 | viability | GCTTCTGCCACGCATCCTGGAGG | KRT77 | ENSG00000189182 | 0.3955506129541899 | [103] | [412] | 3 | hSpCas9 | negative selection | 12383416 | 52692551 | 52692574 | 12 | - | 28162770 | OCIAML3 | viability | GCAGAAGCTGCAGGACCTGGAGG | KRT77 | ENSG00000189182 | 0.4173971229480862 | [62] | [253] | 4 | hSpCas9 | negative selection | 12383417 | 52703271 | 52703294 | 12 | - | 28162770 | OCIAML3 | viability | GGATATGGGATCCATGGAAGGGG | KRT77 | ENSG00000189182 | -0.8372787913365269 | [28] | [48] | -6 | hSpCas9 | negative selection | 12383418 | 52702975 | 52702998 | 12 | - | 28162770 | OCIAML3 | viability | AGAGCCACTTCACCTGGAGGTGG | KRT77 | ENSG00000189182 | 0.01658066807248737 | [92] | [283] | 0 | hSpCas9 | negative selection | 12383419 | 52697768 | 52697791 | 12 | - | 28162770 | OCIAML3 | viability | ACTACATCGGTGACCTGCGGAGG | KRT77 | ENSG00000189182 | 1.0539646579227935 | [55] | [350] | 8 | hSpCas9 | negative selection | 12383420 |