| 52287616 | 52287639 | 12 | - | 26472758 | Jiyoye | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.04607668933783332 | [139] | [108] | 0 | hSpCas9 | negative selection | 86739 | 52286386 | 52286409 | 12 | - | 26472758 | Jiyoye | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.9541610979397244 | [166] | [64] | -6 | hSpCas9 | negative selection | 86740 | 52291455 | 52291478 | 12 | - | 26472758 | Jiyoye | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 1.2097293172996562 | [85] | [149] | 7 | hSpCas9 | negative selection | 86741 | 52291439 | 52291462 | 12 | - | 26472758 | Jiyoye | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.029939914939413947 | [338] | [260] | 0 | hSpCas9 | negative selection | 86742 | 52286811 | 52286834 | 12 | - | 26472758 | Jiyoye | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.6489933014299715 | [136] | [161] | 5 | hSpCas9 | negative selection | 86743 | 52287310 | 52287333 | 12 | - | 26472758 | Jiyoye | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.3410861910481008 | [133] | [127] | 2 | hSpCas9 | negative selection | 86744 | 52288121 | 52288144 | 12 | + | 26472758 | Jiyoye | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | -0.8532619128418812 | [332] | [138] | -5 | hSpCas9 | negative selection | 86745 | 52288035 | 52288058 | 12 | + | 26472758 | Jiyoye | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.32510424856684006 | [216] | [204] | 2 | hSpCas9 | negative selection | 86746 | 52286334 | 52286357 | 12 | - | 26472758 | Jiyoye | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -1.3406375948973253 | [177] | [52] | -7 | hSpCas9 | negative selection | 86747 | 52286434 | 52286457 | 12 | + | 26472758 | Jiyoye | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | 1.3880665585581686 | [75] | [149] | 8 | hSpCas9 | negative selection | 86748 | 52287616 | 52287639 | 12 | - | 26472758 | KBM7 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.5762384156602078 | [683,385] | [456,284] | 6 | hSpCas9 | negative selection | 277857 | 52286386 | 52286409 | 12 | - | 26472758 | KBM7 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | 0.36118953684614463 | [679,669] | [553,279] | 4 | hSpCas9 | negative selection | 277858 | 52291455 | 52291478 | 12 | - | 26472758 | KBM7 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.5678157805156365 | [688,573] | [604,288] | 6 | hSpCas9 | negative selection | 277859 | 52291439 | 52291462 | 12 | - | 26472758 | KBM7 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.14081151494208788 | [1134,1004] | [592,518] | 1 | hSpCas9 | negative selection | 277860 | 52286811 | 52286834 | 12 | - | 26472758 | KBM7 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.9490300204504186 | [744,678] | [978,348] | 9 | hSpCas9 | negative selection | 277861 | 52287310 | 52287333 | 12 | - | 26472758 | KBM7 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.28252040528443345 | [285,369] | [172,206] | 3 | hSpCas9 | negative selection | 277862 | 52288121 | 52288144 | 12 | + | 26472758 | KBM7 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.8166361410620637 | [1192,1164] | [848,1096] | 8 | hSpCas9 | negative selection | 277863 | 52288035 | 52288058 | 12 | + | 26472758 | KBM7 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.461039580265181 | [1280,1631] | [724,1167] | 5 | hSpCas9 | negative selection | 277864 | 52286334 | 52286357 | 12 | - | 26472758 | KBM7 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.2172265275093903 | [259,341] | [113,132] | -2 | hSpCas9 | negative selection | 277865 | 52286434 | 52286457 | 12 | + | 26472758 | KBM7 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | 0.5132611141730021 | [552,436] | [285,368] | 5 | hSpCas9 | negative selection | 277866 | 52287616 | 52287639 | 12 | - | 26472758 | Raji | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.09478349859396593 | [229] | [56] | 0 | hSpCas9 | negative selection | 468975 | 52286386 | 52286409 | 12 | - | 26472758 | Raji | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -1.1405439780699862 | [284] | [29] | -7 | hSpCas9 | negative selection | 468976 | 52291455 | 52291478 | 12 | - | 26472758 | Raji | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | -0.17438743304178028 | [247] | [50] | -1 | hSpCas9 | negative selection | 468977 | 52291439 | 52291462 | 12 | - | 26472758 | Raji | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.06722640890161657 | [509] | [123] | 0 | hSpCas9 | negative selection | 468978 | 52286811 | 52286834 | 12 | - | 26472758 | Raji | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 1.2210403171691668 | [182] | [98] | 9 | hSpCas9 | negative selection | 468979 | 52287310 | 52287333 | 12 | - | 26472758 | Raji | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.5951773770877574 | [173] | [60] | 5 | hSpCas9 | negative selection | 468980 | 52288121 | 52288144 | 12 | + | 26472758 | Raji | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.12425735393799564 | [679] | [171] | 1 | hSpCas9 | negative selection | 468981 | 52288035 | 52288058 | 12 | + | 26472758 | Raji | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.6160930029196003 | [640] | [227] | 6 | hSpCas9 | negative selection | 468982 | 52286334 | 52286357 | 12 | - | 26472758 | Raji | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -2.1474303636552254 | [209] | [10] | -8 | hSpCas9 | negative selection | 468983 | 52286434 | 52286457 | 12 | + | 26472758 | Raji | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.17133249269246406 | [295] | [60] | -1 | hSpCas9 | negative selection | 468984 | 52287616 | 52287639 | 12 | - | 26472758 | K562 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.9297387162819526 | [272] | [438] | 7 | hSpCas9 | negative selection | 660093 | 52286386 | 52286409 | 12 | - | 26472758 | K562 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | 1.7132327446930542 | [417] | [1156] | 9 | hSpCas9 | negative selection | 660094 | 52291455 | 52291478 | 12 | - | 26472758 | K562 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.40687617874866316 | [494] | [553] | 3 | hSpCas9 | negative selection | 660095 | 52291439 | 52291462 | 12 | - | 26472758 | K562 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.384537145973352 | [901] | [993] | 3 | hSpCas9 | negative selection | 660096 | 52286811 | 52286834 | 12 | - | 26472758 | K562 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.3388209523820688 | [487] | [520] | 2 | hSpCas9 | negative selection | 660097 | 52287310 | 52287333 | 12 | - | 26472758 | K562 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.8293812283876031 | [241] | [362] | 7 | hSpCas9 | negative selection | 660098 | 52288121 | 52288144 | 12 | + | 26472758 | K562 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.10377286615220749 | [1194] | [1083] | 0 | hSpCas9 | negative selection | 660099 | 52288035 | 52288058 | 12 | + | 26472758 | K562 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.31213304626279226 | [1310] | [1373] | 2 | hSpCas9 | negative selection | 660100 | 52286334 | 52286357 | 12 | - | 26472758 | K562 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -2.660332957185737 | [336] | [44] | -8 | hSpCas9 | negative selection | 660101 | 52286434 | 52286457 | 12 | + | 26472758 | K562 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -1.1174888051895613 | [310] | [120] | -6 | hSpCas9 | negative selection | 660102 | 52286342 | 52286365 | 12 | + | 26627737 | DLD1 | viability | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 0.7267319426201881 | [88] | [27,6,93] | 7 | hSpCas9 | negative selection | 784215 | 52286389 | 52286412 | 12 | - | 26627737 | DLD1 | viability | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -1.052285733552587 | [1260] | [261,39,251] | -7 | hSpCas9 | negative selection | 784216 | 52286396 | 52286419 | 12 | - | 26627737 | DLD1 | viability | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | -0.006332839140088753 | [1252] | [325,416,422] | 0 | hSpCas9 | negative selection | 784217 | 52291439 | 52291462 | 12 | + | 26627737 | DLD1 | viability | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.2684346565653921 | [1208] | [183,342,401] | -3 | hSpCas9 | negative selection | 784218 | 52286342 | 52286365 | 12 | + | 26627737 | GBM cells | viability after 5 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 0.6694320287629183 | [33] | [37,19] | 8 | hSpCas9 | negative selection | 866530 | 52286389 | 52286412 | 12 | - | 26627737 | GBM cells | viability after 5 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.23700861304476883 | [455] | [184,229] | -4 | hSpCas9 | negative selection | 866531 | 52286396 | 52286419 | 12 | - | 26627737 | GBM cells | viability after 5 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.20303547276267864 | [374] | [241,220] | 3 | hSpCas9 | negative selection | 866532 | 52291439 | 52291462 | 12 | + | 26627737 | GBM cells | viability after 5 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.3447136279352163 | [405] | [232,319] | 5 | hSpCas9 | negative selection | 866533 | 52286342 | 52286365 | 12 | + | 26627737 | GBM cells | viability after 13 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 0.20851705913916563 | [33] | [33,10] | 2 | hSpCas9 | negative selection | 948845 | 52286389 | 52286412 | 12 | - | 26627737 | GBM cells | viability after 13 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.06980792734186225 | [455] | [243,228] | -1 | hSpCas9 | negative selection | 948846 | 52286396 | 52286419 | 12 | - | 26627737 | GBM cells | viability after 13 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.3976434264929446 | [374] | [347,202] | 5 | hSpCas9 | negative selection | 948847 | 52291439 | 52291462 | 12 | + | 26627737 | GBM cells | viability after 13 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.47606046622864806 | [405] | [285,322] | 6 | hSpCas9 | negative selection | 948848 | 52286342 | 52286365 | 12 | + | 26627737 | GBM cells | viability after 21 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 1.6135167408982731 | [33] | [55,56] | 9 | hSpCas9 | negative selection | 1031160 | 52286389 | 52286412 | 12 | - | 26627737 | GBM cells | viability after 21 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.3585394986848085 | [455] | [187,197] | -3 | hSpCas9 | negative selection | 1031161 | 52286396 | 52286419 | 12 | - | 26627737 | GBM cells | viability after 21 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.9704544246823135 | [374] | [417,381] | 8 | hSpCas9 | negative selection | 1031162 | 52291439 | 52291462 | 12 | + | 26627737 | GBM cells | viability after 21 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 1.152254853784563 | [405] | [507,473] | 9 | hSpCas9 | negative selection | 1031163 | 52286342 | 52286365 | 12 | + | 26627737 | RPE1 | viability after 9 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 1.8451884602460824 | [36] | [38,44] | 8 | hSpCas9 | negative selection | 1113475 | 52286389 | 52286412 | 12 | - | 26627737 | RPE1 | viability after 9 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.13996794722457628 | [1467] | [522,484] | 1 | hSpCas9 | negative selection | 1113476 | 52286396 | 52286419 | 12 | - | 26627737 | RPE1 | viability after 9 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.7903921340976884 | [1190] | [650,636] | 5 | hSpCas9 | negative selection | 1113477 | 52291439 | 52291462 | 12 | + | 26627737 | RPE1 | viability after 9 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.7745747231370055 | [3731] | [737,611] | -5 | hSpCas9 | negative selection | 1113478 | 52286342 | 52286365 | 12 | + | 26627737 | RPE1 | viability after 12 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 1.0552268660503392 | [36] | [8,32] | 6 | hSpCas9 | negative selection | 1195790 | 52286389 | 52286412 | 12 | - | 26627737 | RPE1 | viability after 12 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.14749292813312564 | [1467] | [346,531] | 1 | hSpCas9 | negative selection | 1195791 | 52286396 | 52286419 | 12 | - | 26627737 | RPE1 | viability after 12 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.7311874505568238 | [1190] | [536,524] | 5 | hSpCas9 | negative selection | 1195792 | 52291439 | 52291462 | 12 | + | 26627737 | RPE1 | viability after 12 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.8109761085467011 | [3731] | [741,390] | -5 | hSpCas9 | negative selection | 1195793 | 52286342 | 52286365 | 12 | + | 26627737 | RPE1 | viability after 15 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 1.739245199366513 | [36] | [9,58] | 8 | hSpCas9 | negative selection | 1278105 | 52286389 | 52286412 | 12 | - | 26627737 | RPE1 | viability after 15 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.3689688948472918 | [1467] | [463,605] | 2 | hSpCas9 | negative selection | 1278106 | 52286396 | 52286419 | 12 | - | 26627737 | RPE1 | viability after 15 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 1.0567963805985667 | [1190] | [679,720] | 6 | hSpCas9 | negative selection | 1278107 | 52291439 | 52291462 | 12 | + | 26627737 | RPE1 | viability after 15 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -1.175252609139425 | [3731] | [440,492] | -6 | hSpCas9 | negative selection | 1278108 | 52286342 | 52286365 | 12 | + | 26627737 | RPE1 | viability after 18 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 2.3013293014966174 | [36] | [40,57] | 9 | hSpCas9 | negative selection | 1360420 | 52286389 | 52286412 | 12 | - | 26627737 | RPE1 | viability after 18 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.14873200161098565 | [1467] | [298,588] | 1 | hSpCas9 | negative selection | 1360421 | 52286396 | 52286419 | 12 | - | 26627737 | RPE1 | viability after 18 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.594890165965264 | [1190] | [585,377] | 4 | hSpCas9 | negative selection | 1360422 | 52291439 | 52291462 | 12 | + | 26627737 | RPE1 | viability after 18 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.5182659718842548 | [3731] | [883,509] | -3 | hSpCas9 | negative selection | 1360423 | 52286342 | 52286365 | 12 | + | 26627737 | HeLa | viability after 8 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -0.7183996611154218 | [134] | [11,40,47] | -6 | hSpCas9 | negative selection | 1442735 | 52286389 | 52286412 | 12 | - | 26627737 | HeLa | viability after 8 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.8046198970208908 | [720] | [234,46,262] | -7 | hSpCas9 | negative selection | 1442736 | 52286396 | 52286419 | 12 | - | 26627737 | HeLa | viability after 8 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.6047642986047584 | [624] | [337,322,552] | 5 | hSpCas9 | negative selection | 1442737 | 52291439 | 52291462 | 12 | + | 26627737 | HeLa | viability after 8 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 1.1411418643820983 | [498] | [376,272,744] | 8 | hSpCas9 | negative selection | 1442738 | 52286342 | 52286365 | 12 | + | 26627737 | HeLa | viability after 12 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 0.5604203413923636 | [134] | [105,105,32] | 5 | hSpCas9 | negative selection | 1525050 | 52286389 | 52286412 | 12 | - | 26627737 | HeLa | viability after 12 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.3256637283815379 | [720] | [285,328,89] | -3 | hSpCas9 | negative selection | 1525051 | 52286396 | 52286419 | 12 | - | 26627737 | HeLa | viability after 12 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 1.0338598696780714 | [624] | [566,468,557] | 7 | hSpCas9 | negative selection | 1525052 | 52291439 | 52291462 | 12 | + | 26627737 | HeLa | viability after 12 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.5144704700292388 | [498] | [119,347,404] | 4 | hSpCas9 | negative selection | 1525053 | 52286342 | 52286365 | 12 | + | 26627737 | HeLa | viability after 15 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -1.4339224203927716 | [134] | [1,29,29] | -8 | hSpCas9 | negative selection | 1607365 | 52286389 | 52286412 | 12 | - | 26627737 | HeLa | viability after 15 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.4577468421658127 | [720] | [115,196,338] | -4 | hSpCas9 | negative selection | 1607366 | 52286396 | 52286419 | 12 | - | 26627737 | HeLa | viability after 15 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.6134573671726408 | [624] | [197,513,463] | 5 | hSpCas9 | negative selection | 1607367 | 52291439 | 52291462 | 12 | + | 26627737 | HeLa | viability after 15 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.849429150895078 | [498] | [167,235,723] | 6 | hSpCas9 | negative selection | 1607368 | 52286342 | 52286365 | 12 | + | 26627737 | HeLa | viability after 18 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -1.3772423586727518 | [134] | [1,25,29] | -8 | hSpCas9 | negative selection | 1689680 | 52286389 | 52286412 | 12 | - | 26627737 | HeLa | viability after 18 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.4983223290638872 | [720] | [75,150,338] | -4 | hSpCas9 | negative selection | 1689681 | 52286396 | 52286419 | 12 | - | 26627737 | HeLa | viability after 18 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.6147225341980639 | [624] | [133,424,463] | 5 | hSpCas9 | negative selection | 1689682 | 52291439 | 52291462 | 12 | + | 26627737 | HeLa | viability after 18 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.8513452178834002 | [498] | [113,194,723] | 6 | hSpCas9 | negative selection | 1689683 | 52286342 | 52286365 | 12 | + | 26627737 | HCT116 | viability after 6 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 0.06502482617128091 | [9] | [0,1] | 0 | hSpCas9 | negative selection | 1771995 | 52286389 | 52286412 | 12 | - | 26627737 | HCT116 | viability after 6 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.37165707782819857 | [1030] | [239,192] | 2 | hSpCas9 | negative selection | 1771996 | 52286396 | 52286419 | 12 | - | 26627737 | HCT116 | viability after 6 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 1.5305181409971418 | [1119] | [177,690] | 7 | hSpCas9 | negative selection | 1771997 | 52291439 | 52291462 | 12 | + | 26627737 | HCT116 | viability after 6 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 1.11185411621118 | [1391] | [519,446] | 6 | hSpCas9 | negative selection | 1771998 | 52286342 | 52286365 | 12 | + | 26627737 | HCT116 | viability after 8 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -0.20389827641268754 | [44] | [6,8,47] | -2 | hSpCas9 | negative selection | 1854310 | 52286389 | 52286412 | 12 | - | 26627737 | HCT116 | viability after 8 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.13896929918564827 | [521] | [291,198,456] | 1 | hSpCas9 | negative selection | 1854311 | 52286396 | 52286419 | 12 | - | 26627737 | HCT116 | viability after 8 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | -0.09524334990798766 | [577] | [356,199,337] | -1 | hSpCas9 | negative selection | 1854312 | 52291439 | 52291462 | 12 | + | 26627737 | HCT116 | viability after 8 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.03233605488184843 | [580] | [274,228,432] | 0 | hSpCas9 | negative selection | 1854313 | 52286342 | 52286365 | 12 | + | 26627737 | HCT116 | viability after 9 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -1.4169382835338942 | [9] | [0,0] | -7 | hSpCas9 | negative selection | 1936625 | 52286389 | 52286412 | 12 | - | 26627737 | HCT116 | viability after 9 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 1.1176406478703753 | [1030] | [507,667] | 7 | hSpCas9 | negative selection | 1936626 | 52286396 | 52286419 | 12 | - | 26627737 | HCT116 | viability after 9 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 1.0756779416371076 | [1119] | [836,466] | 7 | hSpCas9 | negative selection | 1936627 | 52291439 | 52291462 | 12 | + | 26627737 | HCT116 | viability after 9 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.75693609071924 | [1391] | [874,432] | 5 | hSpCas9 | negative selection | 1936628 | 52286342 | 52286365 | 12 | + | 26627737 | HCT116 | viability after 12 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -0.1699543574781237 | [44] | [31,16,12] | -2 | hSpCas9 | negative selection | 2018940 | 52286389 | 52286412 | 12 | - | 26627737 | HCT116 | viability after 12 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.22008719084687378 | [521] | [225,178,300] | -2 | hSpCas9 | negative selection | 2018941 | 52286396 | 52286419 | 12 | - | 26627737 | HCT116 | viability after 12 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.29588276049319573 | [577] | [411,361,340] | 3 | hSpCas9 | negative selection | 2018942 | 52291439 | 52291462 | 12 | + | 26627737 | HCT116 | viability after 12 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.49656538810963663 | [580] | [167,236,248] | -5 | hSpCas9 | negative selection | 2018943 | 52286342 | 52286365 | 12 | + | 26627737 | HCT116 | viability after 15 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -0.9619892011743696 | [44] | [21,16,1] | -7 | hSpCas9 | negative selection | 2101255 | 52286389 | 52286412 | 12 | - | 26627737 | HCT116 | viability after 15 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.03828545010076201 | [521] | [369,198,315] | 0 | hSpCas9 | negative selection | 2101256 | 52286396 | 52286419 | 12 | - | 26627737 | HCT116 | viability after 15 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.31478219992500334 | [577] | [650,318,298] | 3 | hSpCas9 | negative selection | 2101257 | 52291439 | 52291462 | 12 | + | 26627737 | HCT116 | viability after 15 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.2495328425565524 | [580] | [370,345,468] | 2 | hSpCas9 | negative selection | 2101258 | 52286342 | 52286365 | 12 | + | 26627737 | HCT116 | viability after 18 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -4.443300720674253 | [44] | [0,0,0] | -9 | hSpCas9 | negative selection | 2183570 | 52286389 | 52286412 | 12 | - | 26627737 | HCT116 | viability after 18 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.41887740122057693 | [521] | [406,172,447] | 3 | hSpCas9 | negative selection | 2183571 | 52286396 | 52286419 | 12 | - | 26627737 | HCT116 | viability after 18 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.707394644526361 | [577] | [628,323,422] | 6 | hSpCas9 | negative selection | 2183572 | 52291439 | 52291462 | 12 | + | 26627737 | HCT116 | viability after 18 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.6234864247370959 | [580] | [229,294,798] | 5 | hSpCas9 | negative selection | 2183573 | 52291439 | 52291462 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.007272385470550355 | [3,3] | [3,2] | 0 | hSpCas9 | positive selection | 2998288 | 52291403 | 52291426 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCATCTCGGCCTGCGGGCCGCGG | KRT81 | ENSG00000205426 | -0.23002806104619344 | [3,2] | [3,0] | -3 | hSpCas9 | positive selection | 2998289 | 52290164 | 52290187 | 12 | - | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCTACATCGAGACTCTGCGGCGG | KRT81 | ENSG00000205426 | -0.30573777486552467 | [4,3] | [4,0] | -4 | hSpCas9 | positive selection | 2998290 | 52291209 | 52291232 | 12 | + | 27453484 | HT29 | resistance to T3SS1-dependent cytotoxicity | GCTCTCGTTGACCGACACGGTGG | KRT81 | ENSG00000205426 | -0.27237871874462705 | [2,2] | [3,0] | -4 | hSpCas9 | positive selection | 2998291 | 52291439 | 52291462 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.3402798020838401 | [3,3] | [2,3] | 6 | hSpCas9 | positive selection | 3066146 | 52291403 | 52291426 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCATCTCGGCCTGCGGGCCGCGG | KRT81 | ENSG00000205426 | 0.6605481622307506 | [3,3] | [4,2] | 9 | hSpCas9 | positive selection | 3066147 | 52290164 | 52290187 | 12 | - | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCTACATCGAGACTCTGCGGCGG | KRT81 | ENSG00000205426 | -0.641217789480756 | [4,4] | [2,0] | -8 | hSpCas9 | positive selection | 3066148 | 52291209 | 52291232 | 12 | + | 27453484 | HT29 | resistance to T3SS2-dependent cytotoxicity | GCTCTCGTTGACCGACACGGTGG | KRT81 | ENSG00000205426 | -0.3822559285847362 | [2,2] | [0,1] | -5 | hSpCas9 | positive selection | 3066149 | 52290091 | 52290114 | 12 | + | 27383988 | 293T | resistance to West Nile virus (flavivirus) | CCTCCAGCACCTCCTGCACGTGG | KRT81 | ENSG00000205426 | 1.3504356158373165 | [59,59] | [0,0] | 6 | hSpCas9 | positive selection | 3376366 | 52291439 | 52291462 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 1.45008044042569 | [] | [] | 5 | hSpCas9 | negative selection | 3435745 | 52291403 | 52291426 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCATCTCGGCCTGCGGGCCGCGG | KRT81 | ENSG00000205426 | 0.0222377945667027 | [] | [] | 0 | hSpCas9 | negative selection | 3435746 | 52290164 | 52290187 | 12 | - | 26780180 | HT29 | viability (Avana library 4 designs) | GCTACATCGAGACTCTGCGGCGG | KRT81 | ENSG00000205426 | 1.11004486609376 | [] | [] | 4 | hSpCas9 | negative selection | 3435747 | 52291208 | 52291231 | 12 | + | 26780180 | HT29 | viability (Avana library 4 designs) | GCTCTCGTTGACCGACACGGTGG | KRT81 | ENSG00000205426 | 0.795303012213112 | [] | [] | 3 | hSpCas9 | negative selection | 3435748 | 52291439 | 52291462 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 4.33279141506987 | [] | [] | 7 | hSpCas9 | negative selection | 3523461 | 52291403 | 52291426 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCATCTCGGCCTGCGGGCCGCGG | KRT81 | ENSG00000205426 | 8.20716498976818 | [] | [] | 9 | hSpCas9 | negative selection | 3523462 | 52290164 | 52290187 | 12 | - | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTACATCGAGACTCTGCGGCGG | KRT81 | ENSG00000205426 | -4.57436712838603 | [] | [] | -5 | hSpCas9 | negative selection | 3523463 | 52291208 | 52291231 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GCTCTCGTTGACCGACACGGTGG | KRT81 | ENSG00000205426 | -0.54694717401923 | [] | [] | 0 | hSpCas9 | negative selection | 3523464 | 52290205 | 52290228 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | GGTTGCTCTGGCAACACTCGCGG | KRT81 | ENSG00000205426 | -1.12877507837518 | [] | [] | -1 | hSpCas9 | negative selection | 3523465 | 52288417 | 52288440 | 12 | + | 26780180 | A375 | viability (Avana lentiCRISPRv2) | CCTCCAGGTCTGACTTGCGGAGG | KRT81 | ENSG00000205426 | -0.865548597827036 | [] | [] | -1 | hSpCas9 | negative selection | 3523466 | 52291439 | 52291462 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 4.65798656166689 | [] | [] | 4 | hSpCas9 | negative selection | 3632120 | 52291403 | 52291426 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCATCTCGGCCTGCGGGCCGCGG | KRT81 | ENSG00000205426 | -1.07231818104629 | [] | [] | -2 | hSpCas9 | negative selection | 3632121 | 52290164 | 52290187 | 12 | - | 26780180 | A375 | viability (Avana lentiGuide) | GCTACATCGAGACTCTGCGGCGG | KRT81 | ENSG00000205426 | 9.93219430124332 | [] | [] | 6 | hSpCas9 | negative selection | 3632122 | 52291208 | 52291231 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | GCTCTCGTTGACCGACACGGTGG | KRT81 | ENSG00000205426 | 7.71364695024489 | [] | [] | 6 | hSpCas9 | negative selection | 3632123 | 52290205 | 52290228 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | GGTTGCTCTGGCAACACTCGCGG | KRT81 | ENSG00000205426 | 14.7286359287494 | [] | [] | 8 | hSpCas9 | negative selection | 3632124 | 52288417 | 52288440 | 12 | + | 26780180 | A375 | viability (Avana lentiGuide) | CCTCCAGGTCTGACTTGCGGAGG | KRT81 | ENSG00000205426 | 19.7611995193371 | [] | [] | 8 | hSpCas9 | negative selection | 3632125 | 52291439 | 52291462 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.17952770354279277 | [4] | [5,5] | 5 | hSpCas9 | positive selection | 3740779 | 52291403 | 52291426 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCATCTCGGCCTGCGGGCCGCGG | KRT81 | ENSG00000205426 | 0.3142620593752105 | [4] | [6,4] | 8 | hSpCas9 | positive selection | 3740780 | 52290164 | 52290187 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTACATCGAGACTCTGCGGCGG | KRT81 | ENSG00000205426 | -0.28694762707589017 | [5] | [4,3] | -4 | hSpCas9 | positive selection | 3740781 | 52291208 | 52291231 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GCTCTCGTTGACCGACACGGTGG | KRT81 | ENSG00000205426 | -0.5467679391066316 | [4] | [2,2] | -7 | hSpCas9 | positive selection | 3740782 | 52290205 | 52290228 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | GGTTGCTCTGGCAACACTCGCGG | KRT81 | ENSG00000205426 | -0.1134138888852908 | [4] | [5,2] | -2 | hSpCas9 | positive selection | 3740783 | 52288417 | 52288440 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiCRISPRv2) | CCTCCAGGTCTGACTTGCGGAGG | KRT81 | ENSG00000205426 | -0.2384738559804451 | [4] | [4,3] | -4 | hSpCas9 | positive selection | 3740784 | 52291439 | 52291462 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.038961950615768993 | [5] | [4,4] | 0 | hSpCas9 | positive selection | 3849386 | 52291403 | 52291426 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCATCTCGGCCTGCGGGCCGCGG | KRT81 | ENSG00000205426 | 0.0586405457384403 | [5] | [5,4] | 1 | hSpCas9 | positive selection | 3849387 | 52290164 | 52290187 | 12 | - | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTACATCGAGACTCTGCGGCGG | KRT81 | ENSG00000205426 | -0.26917879326087957 | [6] | [4,3] | -4 | hSpCas9 | positive selection | 3849388 | 52291208 | 52291231 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GCTCTCGTTGACCGACACGGTGG | KRT81 | ENSG00000205426 | -0.6280793466894401 | [4] | [0,2] | -7 | hSpCas9 | positive selection | 3849389 | 52290205 | 52290228 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | GGTTGCTCTGGCAACACTCGCGG | KRT81 | ENSG00000205426 | -1.0464781177799236 | [4] | [1,1] | -8 | hSpCas9 | positive selection | 3849390 | 52288417 | 52288440 | 12 | + | 26780180 | A375 | resistance to vemurafenib (Avana lentiGuide) | CCTCCAGGTCTGACTTGCGGAGG | KRT81 | ENSG00000205426 | -0.21375992217548784 | [4] | [3,3] | -3 | hSpCas9 | positive selection | 3849391 | 52289226 | 52289249 | 12 | - | 26780180 | A375 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 0.707351721892901 | [] | [] | 2 | hSpCas9 | negative selection | 3955459 | 52288046 | 52288069 | 12 | - | 26780180 | A375 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | -0.0340296660730419 | [] | [] | -1 | hSpCas9 | negative selection | 3955460 | 52288035 | 52288058 | 12 | + | 26780180 | A375 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.250166052601607 | [] | [] | 0 | hSpCas9 | negative selection | 3955461 | 52289226 | 52289249 | 12 | - | 26780180 | HT29 | viability (GeCKOv2 library) | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 1.08829960118754 | [] | [] | 5 | hSpCas9 | negative selection | 4063425 | 52288046 | 52288069 | 12 | - | 26780180 | HT29 | viability (GeCKOv2 library) | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.218934442889994 | [] | [] | 0 | hSpCas9 | negative selection | 4063426 | 52288035 | 52288058 | 12 | + | 26780180 | HT29 | viability (GeCKOv2 library) | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.134480434705944 | [] | [] | 0 | hSpCas9 | negative selection | 4063427 | 52288035 | 52288058 | 12 | + | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.3290387907758774 | [3] | [4,3] | 6 | hSpCas9 | positive selection | 4279233 | 52288046 | 52288069 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.29373171324990915 | [3] | [4,2] | 6 | hSpCas9 | positive selection | 4279234 | 52289226 | 52289249 | 12 | - | 26780180 | A375 | resistance to vemurafenib (GeCKOv2 lentiGuide) | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 0.3327054903543492 | [3] | [3,4] | 6 | hSpCas9 | positive selection | 4343490 | 52287285 | 52287307 | 12 | + | 27760321 | OCIAML3 | viability | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -0.2675442135586378 | [1008,846] | [475,762] | -3 | hSpCas9 | negative selection | 4413255 | 52287285 | 52287307 | 12 | + | 27760321 | OCIAML2 | viability | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -1.0737793389788626 | [1008,846] | [233,514] | -7 | hSpCas9 | negative selection | 4496718 | 52287285 | 52287307 | 12 | + | 27760321 | MV411 | viability | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -1.0466461248549217 | [1008,846] | [176,472] | -6 | hSpCas9 | negative selection | 4580181 | 52287285 | 52287307 | 12 | + | 27760321 | HL60 | viability | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -0.06023336156633641 | [1008,846] | [665,785] | 0 | hSpCas9 | negative selection | 4663644 | 52287285 | 52287307 | 12 | + | 27760321 | HT1080 | viability | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -3.8211464773193633 | [846,660] | [15,26] | -8 | hSpCas9 | negative selection | 4747107 | 52287285 | 52287307 | 12 | + | 27760321 | HT29 | viability after 7 days | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | 0.0011603951035796811 | [846,660] | [1132,688,1105] | 0 | hSpCas9 | negative selection | 4830570 | 52287285 | 52287307 | 12 | + | 27760321 | HT29 | viability after 25 days | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -0.3679708135819141 | [846,660] | [804,420,778] | -4 | hSpCas9 | negative selection | 4914033 | 52287285 | 52287307 | 12 | + | 27760321 | HT29 | viability after 22 days | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -0.6303658551099949 | [846,660] | [620,473,592] | -5 | hSpCas9 | negative selection | 4997496 | 52287285 | 52287307 | 12 | + | 27760321 | HT29 | viability after 19 days | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -0.3637212820112806 | [846,660] | [726,645,643] | -3 | hSpCas9 | negative selection | 5080959 | 52287285 | 52287307 | 12 | + | 27760321 | HT29 | viability after 16 days | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -0.360461606620326 | [846,660] | [668,627,675] | -4 | hSpCas9 | negative selection | 5164422 | 52287285 | 52287307 | 12 | + | 27760321 | HT29 | viability after 13 days | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -0.22163562474867782 | [846,660] | [546,820,874] | -3 | hSpCas9 | negative selection | 5247885 | 52287285 | 52287307 | 12 | + | 27760321 | HT29 | viability after 10 days | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | 0.24301697297024316 | [846,660] | [1019,851,1454] | 3 | hSpCas9 | negative selection | 5331348 | 52287285 | 52287307 | 12 | + | 27760321 | MOLM13 | viability | TGCTCAGACTGGGCCACCGCGG | KRT81 | ENSG00000205426 | -1.0242048108659485 | [1008,846] | [216,289] | -6 | hSpCas9 | negative selection | 5414811 | 52287777 | 52287800 | 12 | + | 27661255 | K562 | viability | GACACCACAGATGATTTTGCAGG | KRT81 | ENSG00000205426 | 0.2163074693756916 | [645,791] | [822,529] | 7 | dCas9-KRAB | negative selection | 5489386 | 52287869 | 52287892 | 12 | + | 27661255 | K562 | viability | GCCCTCTCTTCTCATCCCTAGGG | KRT81 | ENSG00000205426 | 0.036332465525001356 | [1307,1600] | [1272,1113] | 1 | dCas9-KRAB | negative selection | 5489387 | 52288035 | 52288058 | 12 | + | 27661255 | K562 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | -0.06652335623782166 | [895,741] | [655,601] | -3 | dCas9-KRAB | negative selection | 5489388 | 52287852 | 52287875 | 12 | - | 27661255 | K562 | viability | GAGGGCTGCCAATCTGAGGTTGG | KRT81 | ENSG00000205426 | 0.12722428659313578 | [1054,1366] | [1191,931] | 4 | dCas9-KRAB | negative selection | 5489389 | 52287871 | 52287894 | 12 | - | 27661255 | K562 | viability | GTCCCTAGGGATGAGAAGAGAGG | KRT81 | ENSG00000205426 | 0.019078937366092563 | [447,575] | [377,441] | 0 | dCas9-KRAB | negative selection | 5489390 | 52288035 | 52288058 | 12 | + | 27260156 | BXPC3 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.07167059613609006 | [924] | [1082,853,922,1224] | 1 | hSpCas9 | negative selection | 5551693 | 52288046 | 52288069 | 12 | - | 27260156 | BXPC3 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.21821597606005994 | [712] | [837,820,869,949] | 5 | hSpCas9 | negative selection | 5551694 | 52289226 | 52289249 | 12 | - | 27260156 | BXPC3 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.25662557907194594 | [953] | [837,752,894,855] | -5 | hSpCas9 | negative selection | 5615950 | 52288035 | 52288058 | 12 | + | 27260156 | A673 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.17772195452066242 | [924] | [1434,1130,1133,1352] | 4 | hSpCas9 | negative selection | 5672944 | 52288046 | 52288069 | 12 | - | 27260156 | A673 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.35294345758024237 | [712] | [1058,1065,1231,1004] | 7 | hSpCas9 | negative selection | 5672945 | 52289226 | 52289249 | 12 | - | 27260156 | A673 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.238982314002131 | [953] | [896,931,957,1092] | -5 | hSpCas9 | negative selection | 5737201 | 52288035 | 52288058 | 12 | + | 27260156 | A375 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.31088099024605087 | [924] | [1516,1949,1090,932] | 4 | hSpCas9 | negative selection | 5794195 | 52288046 | 52288069 | 12 | - | 27260156 | A375 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.4493258295080993 | [712] | [1229,1235,1395,743] | 6 | hSpCas9 | negative selection | 5794196 | 52289226 | 52289249 | 12 | - | 27260156 | A375 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.44840721837357944 | [953] | [742,1226,572,780] | -6 | hSpCas9 | negative selection | 5858452 | 52288035 | 52288058 | 12 | + | 27260156 | COLO741 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.13629367888443145 | [924] | [1461,1069,1369] | 3 | hSpCas9 | negative selection | 5915446 | 52288046 | 52288069 | 12 | - | 27260156 | COLO741 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.3461587319295426 | [712] | [1325,1106,1059] | 7 | hSpCas9 | negative selection | 5915447 | 52289226 | 52289249 | 12 | - | 27260156 | COLO741 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.05357189305747667 | [953] | [1321,1188,1032] | -1 | hSpCas9 | negative selection | 5979703 | 52288035 | 52288058 | 12 | + | 27260156 | CAL120 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.1330731594400848 | [924] | [1617,1247,978] | 2 | hSpCas9 | negative selection | 6036697 | 52288046 | 52288069 | 12 | - | 27260156 | CAL120 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.652702995384931 | [712] | [1677,1344,1206] | 8 | hSpCas9 | negative selection | 6036698 | 52289226 | 52289249 | 12 | - | 27260156 | CAL120 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.31424436742787176 | [953] | [1082,886,913] | -4 | hSpCas9 | negative selection | 6100954 | 52288035 | 52288058 | 12 | + | 27260156 | CADOES1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.37962064036996523 | [924] | [979,1224,938,1341] | 6 | hSpCas9 | negative selection | 6157948 | 52288046 | 52288069 | 12 | - | 27260156 | CADOES1 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.39823443566675853 | [712] | [792,850,923,929] | 6 | hSpCas9 | negative selection | 6157949 | 52289226 | 52289249 | 12 | - | 27260156 | CADOES1 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.12354711422103892 | [953] | [966,660,842,784] | -2 | hSpCas9 | negative selection | 6222205 | 52288035 | 52288058 | 12 | + | 27260156 | EWS502 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.15566453289697668 | [924] | [974,1114,1078,1213] | 2 | hSpCas9 | negative selection | 6279199 | 52288046 | 52288069 | 12 | - | 27260156 | EWS502 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.4507564099146568 | [712] | [996,843,1183,1119] | 7 | hSpCas9 | negative selection | 6279200 | 52289226 | 52289249 | 12 | - | 27260156 | EWS502 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.33361859655438797 | [953] | [581,791,928,939] | -5 | hSpCas9 | negative selection | 6343456 | 52288035 | 52288058 | 12 | + | 27260156 | EW8 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | -0.05821056506829658 | [924] | [802,647,747,682] | -1 | hSpCas9 | negative selection | 6400450 | 52288046 | 52288069 | 12 | - | 27260156 | EW8 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.30954318511617585 | [712] | [717,792,662,697] | 5 | hSpCas9 | negative selection | 6400451 | 52289226 | 52289249 | 12 | - | 27260156 | EW8 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.33153495500426755 | [953] | [727,586,586,570] | -6 | hSpCas9 | negative selection | 6464707 | 52288035 | 52288058 | 12 | + | 27260156 | CORL105 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.18206493837432502 | [924] | [1197,1230,1162,1309] | 3 | hSpCas9 | negative selection | 6521701 | 52288046 | 52288069 | 12 | - | 27260156 | CORL105 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.4972752783151817 | [712] | [1487,871,1308,1080] | 8 | hSpCas9 | negative selection | 6521702 | 52289226 | 52289249 | 12 | - | 27260156 | CORL105 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 0.20656685368396754 | [953] | [1277,1307,1395,1188] | 4 | hSpCas9 | negative selection | 6585958 | 52288035 | 52288058 | 12 | + | 27260156 | HS294T | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.3165099785294766 | [924] | [416,336,394,675] | 4 | hSpCas9 | negative selection | 6642952 | 52288046 | 52288069 | 12 | - | 27260156 | HS294T | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.3429631653420069 | [712] | [421,290,326,352] | 4 | hSpCas9 | negative selection | 6642953 | 52289226 | 52289249 | 12 | - | 27260156 | HS294T | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.6315524093809433 | [953] | [261,181,239,272] | -7 | hSpCas9 | negative selection | 6707209 | 52288035 | 52288058 | 12 | + | 27260156 | HCC44 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.42068900788323804 | [924] | [1564,834,1465,1816] | 7 | hSpCas9 | negative selection | 6764203 | 52288046 | 52288069 | 12 | - | 27260156 | HCC44 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.33028111587549136 | [712] | [877,880,1545,845] | 5 | hSpCas9 | negative selection | 6764204 | 52289226 | 52289249 | 12 | - | 27260156 | HCC44 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.018764492114479392 | [953] | [844,1025,1219,1168] | 0 | hSpCas9 | negative selection | 6828460 | 52288035 | 52288058 | 12 | + | 27260156 | G402 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.33491602469300485 | [924] | [1367,1398,1372,1533] | 4 | hSpCas9 | negative selection | 6885454 | 52288046 | 52288069 | 12 | - | 27260156 | G402 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.9408312242971568 | [712] | [1938,1352,1768,1634] | 9 | hSpCas9 | negative selection | 6885455 | 52289226 | 52289249 | 12 | - | 27260156 | G402 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.5825445972193573 | [953] | [624,1031,978,477] | -6 | hSpCas9 | negative selection | 6949711 | 52288035 | 52288058 | 12 | + | 27260156 | L33 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.4159285508864837 | [924] | [1284,461,867,1142] | 8 | hSpCas9 | negative selection | 7006705 | 52288046 | 52288069 | 12 | - | 27260156 | L33 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.042973075904292224 | [712] | [705,362,396,714] | 1 | hSpCas9 | negative selection | 7006706 | 52289226 | 52289249 | 12 | - | 27260156 | L33 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 0.01737703892857434 | [953] | [879,416,693,863] | 0 | hSpCas9 | negative selection | 7070962 | 52288035 | 52288058 | 12 | + | 27260156 | K562 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.27466393265331346 | [924] | [1385,1332,976,392] | 3 | hSpCas9 | negative selection | 7127956 | 52288046 | 52288069 | 12 | - | 27260156 | K562 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.634373637123022 | [712] | [745,1134,953,1067] | 7 | hSpCas9 | negative selection | 7127957 | 52289226 | 52289249 | 12 | - | 27260156 | K562 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.011266031217553873 | [953] | [826,878,674,961] | 0 | hSpCas9 | negative selection | 7192213 | 52288035 | 52288058 | 12 | + | 27260156 | HT29 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.17002264996343242 | [924] | [1495,1290,1197,1105] | 3 | hSpCas9 | negative selection | 7249207 | 52288046 | 52288069 | 12 | - | 27260156 | HT29 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.38496203170474363 | [712] | [1096,1173,1180,1074] | 7 | hSpCas9 | negative selection | 7249208 | 52289226 | 52289249 | 12 | - | 27260156 | HT29 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.3122159040983956 | [953] | [930,1071,831,908] | -6 | hSpCas9 | negative selection | 7313464 | 52288035 | 52288058 | 12 | + | 27260156 | MHHES1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.3833289801674856 | [924] | [1527,1578,1276,1118] | 7 | hSpCas9 | negative selection | 7370458 | 52288046 | 52288069 | 12 | - | 27260156 | MHHES1 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.5005749530231527 | [712] | [1394,1073,1383,776] | 8 | hSpCas9 | negative selection | 7370459 | 52289226 | 52289249 | 12 | - | 27260156 | MHHES1 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 0.11466239298968905 | [953] | [1144,1416,1048,1061] | 2 | hSpCas9 | negative selection | 7434715 | 52288035 | 52288058 | 12 | + | 27260156 | MEWO | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.2042370722801733 | [924] | [1173,1011,838] | 4 | hSpCas9 | negative selection | 7491709 | 52288046 | 52288069 | 12 | - | 27260156 | MEWO | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.09002672116679822 | [712] | [761,696,680] | 2 | hSpCas9 | negative selection | 7491710 | 52289226 | 52289249 | 12 | - | 27260156 | MEWO | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.11330340629510971 | [953] | [895,801,790] | -2 | hSpCas9 | negative selection | 7555966 | 52288035 | 52288058 | 12 | + | 27260156 | LNCAPCLONEFGC | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.2749759306741083 | [924] | [834,1168,1303,782] | 4 | hSpCas9 | negative selection | 7612960 | 52288046 | 52288069 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.5643570523740877 | [712] | [776,889,1477,759] | 8 | hSpCas9 | negative selection | 7612961 | 52289226 | 52289249 | 12 | - | 27260156 | LNCAPCLONEFGC | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.2566939526722911 | [953] | [759,659,808,679] | -4 | hSpCas9 | negative selection | 7677217 | 52288035 | 52288058 | 12 | + | 27260156 | PANC0327 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.5498594783531906 | [924] | [1310,1123,1078,1315] | 7 | hSpCas9 | negative selection | 7734211 | 52288046 | 52288069 | 12 | - | 27260156 | PANC0327 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.12285867706399245 | [712] | [709,652,760,640] | 1 | hSpCas9 | negative selection | 7734212 | 52289226 | 52289249 | 12 | - | 27260156 | PANC0327 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.25590838554001016 | [953] | [740,624,688,796] | -4 | hSpCas9 | negative selection | 7798468 | 52288035 | 52288058 | 12 | + | 27260156 | NCIH2009 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.2796609621294467 | [924] | [1960,1475,1345] | 4 | hSpCas9 | negative selection | 7855462 | 52288046 | 52288069 | 12 | - | 27260156 | NCIH2009 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.6002275944330302 | [712] | [1962,1201,1457] | 8 | hSpCas9 | negative selection | 7855463 | 52289226 | 52289249 | 12 | - | 27260156 | NCIH2009 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.06895052633062926 | [953] | [1436,1367,1035] | -1 | hSpCas9 | negative selection | 7919719 | 52288035 | 52288058 | 12 | + | 27260156 | NCIH1373 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.9046052956720066 | [924] | [1943,1529,2398,502] | 8 | hSpCas9 | negative selection | 7976713 | 52288046 | 52288069 | 12 | - | 27260156 | NCIH1373 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.5533665723258148 | [712] | [1377,916,1250,314] | 5 | hSpCas9 | negative selection | 7976714 | 52289226 | 52289249 | 12 | - | 27260156 | NCIH1373 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.2978874192009099 | [953] | [944,647,1164,193] | -3 | hSpCas9 | negative selection | 8040970 | 52288035 | 52288058 | 12 | + | 27260156 | PATU8902 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.4632991625041901 | [924] | [1952,1647,1653,1875] | 5 | hSpCas9 | negative selection | 8097964 | 52288046 | 52288069 | 12 | - | 27260156 | PATU8902 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 1.0323161166758938 | [712] | [2134,1820,1741,2543] | 9 | hSpCas9 | negative selection | 8097965 | 52289226 | 52289249 | 12 | - | 27260156 | PATU8902 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.5498748802283278 | [953] | [726,648,940,1351] | -5 | hSpCas9 | negative selection | 8162221 | 52288035 | 52288058 | 12 | + | 27260156 | PANC1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.4060052524371466 | [924] | [1274,1221,1206,596] | 6 | hSpCas9 | negative selection | 8219215 | 52288046 | 52288069 | 12 | - | 27260156 | PANC1 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.5243527184907986 | [712] | [966,874,943,742] | 8 | hSpCas9 | negative selection | 8219216 | 52289226 | 52289249 | 12 | - | 27260156 | PANC1 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.10466661799356802 | [953] | [724,905,856,604] | -2 | hSpCas9 | negative selection | 8283472 | 52288035 | 52288058 | 12 | + | 27260156 | PANC0813 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.5387927549357375 | [924] | [2227,982,1397,1751] | 8 | hSpCas9 | negative selection | 8340466 | 52288046 | 52288069 | 12 | - | 27260156 | PANC0813 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.37700259305962946 | [712] | [1426,1241,916,808] | 6 | hSpCas9 | negative selection | 8340467 | 52289226 | 52289249 | 12 | - | 27260156 | PANC0813 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.1889370335684769 | [953] | [962,897,1354,728] | -3 | hSpCas9 | negative selection | 8404723 | 52288035 | 52288058 | 12 | + | 27260156 | RDES | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.18202678098774727 | [924] | [1143,1001,1071,1668] | 3 | hSpCas9 | negative selection | 8461717 | 52288046 | 52288069 | 12 | - | 27260156 | RDES | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.6778864302022474 | [712] | [1119,1158,1435,1595] | 9 | hSpCas9 | negative selection | 8461718 | 52289226 | 52289249 | 12 | - | 27260156 | RDES | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.06007403889928353 | [953] | [934,1203,980,1063] | -1 | hSpCas9 | negative selection | 8525974 | 52288035 | 52288058 | 12 | + | 27260156 | PC3 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.4313420149466455 | [924] | [780,977,2596,1243] | 8 | hSpCas9 | negative selection | 8582968 | 52288046 | 52288069 | 12 | - | 27260156 | PC3 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.32175181276357334 | [712] | [440,817,1298,1302] | 7 | hSpCas9 | negative selection | 8582969 | 52289226 | 52289249 | 12 | - | 27260156 | PC3 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 0.012127901486104209 | [953] | [770,711,1435,1088] | 0 | hSpCas9 | negative selection | 8647225 | 52288035 | 52288058 | 12 | + | 27260156 | PATU8988T | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | -0.2500456706839329 | [924] | [700,588,675,1049] | -4 | hSpCas9 | negative selection | 8704219 | 52288046 | 52288069 | 12 | - | 27260156 | PATU8988T | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.5478208309595978 | [712] | [1528,777,564,1152] | 8 | hSpCas9 | negative selection | 8704220 | 52289226 | 52289249 | 12 | - | 27260156 | PATU8988T | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.31669193074012625 | [953] | [534,1010,713,724] | -5 | hSpCas9 | negative selection | 8768476 | 52288035 | 52288058 | 12 | + | 27260156 | T47D | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | -0.1449582406839649 | [924] | [900,902,851,1258] | -3 | hSpCas9 | negative selection | 8825470 | 52288046 | 52288069 | 12 | - | 27260156 | T47D | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.26119079448641436 | [712] | [1028,1121,793,1029] | 5 | hSpCas9 | negative selection | 8825471 | 52289226 | 52289249 | 12 | - | 27260156 | T47D | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.2969593888215314 | [953] | [873,798,987,966] | -6 | hSpCas9 | negative selection | 8889727 | 52288035 | 52288058 | 12 | + | 27260156 | SU8686 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.4841295176959596 | [924] | [1180,1044,1371,1623] | 7 | hSpCas9 | negative selection | 8946721 | 52288046 | 52288069 | 12 | - | 27260156 | SU8686 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.2762574195006492 | [712] | [638,711,1128,1014] | 5 | hSpCas9 | negative selection | 8946722 | 52289226 | 52289249 | 12 | - | 27260156 | SU8686 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.5044926955834762 | [953] | [638,609,690,745] | -7 | hSpCas9 | negative selection | 9010978 | 52288035 | 52288058 | 12 | + | 27260156 | SKES1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.19191982463623358 | [924] | [1437,1050,893,895] | 4 | hSpCas9 | negative selection | 9067972 | 52288046 | 52288069 | 12 | - | 27260156 | SKES1 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.08565039169072852 | [712] | [873,671,685,782] | 1 | hSpCas9 | negative selection | 9067973 | 52289226 | 52289249 | 12 | - | 27260156 | SKES1 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | 0.10951709943763799 | [953] | [1053,957,1176,913] | 2 | hSpCas9 | negative selection | 9132229 | 52288035 | 52288058 | 12 | + | 27260156 | TOV112D | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.11874598278667403 | [924] | [1066,907,875,1147] | 2 | hSpCas9 | negative selection | 9189223 | 52288046 | 52288069 | 12 | - | 27260156 | TOV112D | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.1162970301575833 | [712] | [741,816,776,766] | 2 | hSpCas9 | negative selection | 9189224 | 52289226 | 52289249 | 12 | - | 27260156 | TOV112D | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.20381009825411645 | [953] | [870,1124,668,730] | -4 | hSpCas9 | negative selection | 9253480 | 52288035 | 52288058 | 12 | + | 27260156 | TC71 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.21288800048570844 | [924] | [1232,971,1256,1127] | 5 | hSpCas9 | negative selection | 9310474 | 52288046 | 52288069 | 12 | - | 27260156 | TC71 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.3588872257422727 | [712] | [988,1010,877,1049] | 8 | hSpCas9 | negative selection | 9310475 | 52289226 | 52289249 | 12 | - | 27260156 | TC71 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.010416221927991076 | [953] | [901,1057,938,1176] | 0 | hSpCas9 | negative selection | 9374731 | 52288035 | 52288058 | 12 | + | 27260156 | TC32 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.3471899664769772 | [924] | [1086,896,1312,1178] | 6 | hSpCas9 | negative selection | 9431725 | 52288046 | 52288069 | 12 | - | 27260156 | TC32 | viability | CTGCATCATTGCCGAGATTAAGG | KRT81 | ENSG00000205426 | 0.3772003752712809 | [712] | [820,428,1176,1255] | 6 | hSpCas9 | negative selection | 9431726 | 52289226 | 52289249 | 12 | - | 27260156 | TC32 | viability | AACAGCTGAGAACGAGTTTGTGG | KRT81 | ENSG00000205426 | -0.07893230493417758 | [953] | [801,589,1210,912] | -1 | hSpCas9 | negative selection | 9495982 | 52286342 | 52286365 | 12 | + | 27869803 | HPAFII | viability after 27 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 0.5661809186989331 | [15] | [24,1,NaN] | 4 | hSpCas9 | negative selection | 9547215 | 52286389 | 52286412 | 12 | - | 27869803 | HPAFII | viability after 27 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.3099293349483727 | [490] | [487,179,NaN] | 2 | hSpCas9 | negative selection | 9547216 | 52286396 | 52286419 | 12 | - | 27869803 | HPAFII | viability after 27 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 1.364653692785601 | [473] | [536,728,NaN] | 9 | hSpCas9 | negative selection | 9547217 | 52291439 | 52291462 | 12 | + | 27869803 | HPAFII | viability after 27 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.15640870069382629 | [365] | [328,118,NaN] | 1 | hSpCas9 | negative selection | 9547218 | 52286342 | 52286365 | 12 | + | 27869803 | HPAFII | viability after 15 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 2.813033993392311 | [15] | [237,47,NaN] | 9 | hSpCas9 | negative selection | 9629664 | 52286389 | 52286412 | 12 | - | 27869803 | HPAFII | viability after 15 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.061049885699099526 | [490] | [917,321,NaN] | 0 | hSpCas9 | negative selection | 9629665 | 52286396 | 52286419 | 12 | - | 27869803 | HPAFII | viability after 15 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.9846812349254734 | [473] | [1004,1009,NaN] | 9 | hSpCas9 | negative selection | 9629666 | 52291439 | 52291462 | 12 | + | 27869803 | HPAFII | viability after 15 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.37068045241777514 | [365] | [560,475,NaN] | 4 | hSpCas9 | negative selection | 9629667 | 52286342 | 52286365 | 12 | + | 27869803 | ASPC1 | viability after 36 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -0.36157214820496675 | [205] | [19,57,78] | -4 | hSpCas9 | negative selection | 9712113 | 52286389 | 52286412 | 12 | - | 27869803 | ASPC1 | viability after 36 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.6427210885028047 | [1030] | [311,526,758] | 6 | hSpCas9 | negative selection | 9712114 | 52286396 | 52286419 | 12 | - | 27869803 | ASPC1 | viability after 36 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 0.8114012088316063 | [1029] | [395,1027,473] | 7 | hSpCas9 | negative selection | 9712115 | 52291439 | 52291462 | 12 | + | 27869803 | ASPC1 | viability after 36 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -1.1922241013934474 | [809] | [81,72,191] | -8 | hSpCas9 | negative selection | 9712116 | 52286342 | 52286365 | 12 | + | 27869803 | PATU8988S | viability after 35 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -1.0536762162525601 | [79] | [24,5,NaN] | -7 | hSpCas9 | negative selection | 9794562 | 52286389 | 52286412 | 12 | - | 27869803 | PATU8988S | viability after 35 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.26757190564486705 | [916] | [219,393,NaN] | -3 | hSpCas9 | negative selection | 9794563 | 52286396 | 52286419 | 12 | - | 27869803 | PATU8988S | viability after 35 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | -0.2999383660002329 | [916] | [297,301,NaN] | -3 | hSpCas9 | negative selection | 9794564 | 52291439 | 52291462 | 12 | + | 27869803 | PATU8988S | viability after 35 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.09358436538728471 | [775] | [250,334,NaN] | -1 | hSpCas9 | negative selection | 9794565 | 52286342 | 52286365 | 12 | + | 27869803 | PATU8988S | viability after 31 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -0.3082935423893032 | [79] | [34,13,NaN] | -4 | hSpCas9 | negative selection | 9877011 | 52286389 | 52286412 | 12 | - | 27869803 | PATU8988S | viability after 31 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | -0.14984351310205124 | [916] | [212,477,NaN] | -2 | hSpCas9 | negative selection | 9877012 | 52286396 | 52286419 | 12 | - | 27869803 | PATU8988S | viability after 31 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | -0.49425993560097264 | [916] | [175,365,NaN] | -5 | hSpCas9 | negative selection | 9877013 | 52291439 | 52291462 | 12 | + | 27869803 | PATU8988S | viability after 31 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | -0.07771774670966525 | [775] | [279,309,NaN] | -1 | hSpCas9 | negative selection | 9877014 | 52286342 | 52286365 | 12 | + | 27869803 | HPAFII | viability after 35 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | -3.0179114470033253 | [15] | [0,0,NaN] | -8 | hSpCas9 | negative selection | 9959460 | 52286389 | 52286412 | 12 | - | 27869803 | HPAFII | viability after 35 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.025367673394858015 | [490] | [323,172,NaN] | 0 | hSpCas9 | negative selection | 9959461 | 52286396 | 52286419 | 12 | - | 27869803 | HPAFII | viability after 35 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 1.611162494602035 | [473] | [408,1097,NaN] | 9 | hSpCas9 | negative selection | 9959462 | 52291439 | 52291462 | 12 | + | 27869803 | HPAFII | viability after 35 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.3590005218707685 | [365] | [215,261,NaN] | 2 | hSpCas9 | negative selection | 9959463 | 52286342 | 52286365 | 12 | + | 27869803 | HPAFII | viability after 31 days | GGTGGTGTTCAATTGGCCGCAGG | KRT81 | ENSG00000205426 | 1.3506468928848392 | [15] | [42,0,NaN] | 8 | hSpCas9 | negative selection | 10041909 | 52286389 | 52286412 | 12 | - | 27869803 | HPAFII | viability after 31 days | CGCTCCGTGCAACGGGAACGTGG | KRT81 | ENSG00000205426 | 0.24065392415261821 | [490] | [371,274,NaN] | 1 | hSpCas9 | negative selection | 10041910 | 52286396 | 52286419 | 12 | - | 27869803 | HPAFII | viability after 31 days | TCTGCAGCGCTCCGTGCAACGGG | KRT81 | ENSG00000205426 | 1.4256488953973103 | [473] | [437,1015,NaN] | 9 | hSpCas9 | negative selection | 10041911 | 52291439 | 52291462 | 12 | + | 27869803 | HPAFII | viability after 31 days | CCCACCAAATCCTGATCCGCAGG | KRT81 | ENSG00000205426 | 0.5240578313923531 | [365] | [325,261,NaN] | 4 | hSpCas9 | negative selection | 10041912 | 52287616 | 52287639 | 12 | - | 28162770 | P31FUJ | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.5022255855103349 | [148] | [247] | 5 | hSpCas9 | negative selection | 10181702 | 52286386 | 52286409 | 12 | - | 28162770 | P31FUJ | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.4409881332525528 | [319] | [276] | -4 | hSpCas9 | negative selection | 10181703 | 52291455 | 52291478 | 12 | - | 28162770 | P31FUJ | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | -0.11432873453452302 | [221] | [240] | -1 | hSpCas9 | negative selection | 10181704 | 52291439 | 52291462 | 12 | - | 28162770 | P31FUJ | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | -0.41701992272459815 | [316] | [278] | -4 | hSpCas9 | negative selection | 10181705 | 52286811 | 52286834 | 12 | - | 28162770 | P31FUJ | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.5361922439444654 | [195] | [333] | 6 | hSpCas9 | negative selection | 10181706 | 52287310 | 52287333 | 12 | - | 28162770 | P31FUJ | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | -0.1000469955626071 | [165] | [181] | -1 | hSpCas9 | negative selection | 10181707 | 52288121 | 52288144 | 12 | + | 28162770 | P31FUJ | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.34613650867900736 | [479] | [716] | 4 | hSpCas9 | negative selection | 10181708 | 52288035 | 52288058 | 12 | + | 28162770 | P31FUJ | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.179000551265164 | [892] | [1187] | 1 | hSpCas9 | negative selection | 10181709 | 52286334 | 52286357 | 12 | - | 28162770 | P31FUJ | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.21997816405679504 | [223] | [225] | -2 | hSpCas9 | negative selection | 10181710 | 52286434 | 52286457 | 12 | + | 28162770 | P31FUJ | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.45582093140029334 | [383] | [328] | -4 | hSpCas9 | negative selection | 10181711 | 52287616 | 52287639 | 12 | - | 28162770 | TF1 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [301] | 1 | hSpCas9 | negative selection | 10351068 | 52286386 | 52286409 | 12 | - | 28162770 | TF1 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [155] | 1 | hSpCas9 | negative selection | 10351069 | 52291455 | 52291478 | 12 | - | 28162770 | TF1 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [272] | 1 | hSpCas9 | negative selection | 10351070 | 52291439 | 52291462 | 12 | - | 28162770 | TF1 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [251] | 1 | hSpCas9 | negative selection | 10351071 | 52286811 | 52286834 | 12 | - | 28162770 | TF1 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [224] | 1 | hSpCas9 | negative selection | 10351072 | 52287310 | 52287333 | 12 | - | 28162770 | TF1 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [122] | 1 | hSpCas9 | negative selection | 10351073 | 52288121 | 52288144 | 12 | + | 28162770 | TF1 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [631] | 1 | hSpCas9 | negative selection | 10351074 | 52288035 | 52288058 | 12 | + | 28162770 | TF1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [639] | 1 | hSpCas9 | negative selection | 10351075 | 52286334 | 52286357 | 12 | - | 28162770 | TF1 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [188] | 1 | hSpCas9 | negative selection | 10351076 | 52286434 | 52286457 | 12 | + | 28162770 | TF1 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | NaN | [NaN] | [126] | 1 | hSpCas9 | negative selection | 10351077 | 52287616 | 52287639 | 12 | - | 28162770 | SKM1 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 1.5845041676357214 | [52] | [280] | 9 | hSpCas9 | negative selection | 10520434 | 52286386 | 52286409 | 12 | - | 28162770 | SKM1 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.6726240739837789 | [54] | [60] | -5 | hSpCas9 | negative selection | 10520435 | 52291455 | 52291478 | 12 | - | 28162770 | SKM1 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.29347551939793054 | [53] | [116] | 3 | hSpCas9 | negative selection | 10520436 | 52291439 | 52291462 | 12 | - | 28162770 | SKM1 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.2633897932086392 | [81] | [173] | 2 | hSpCas9 | negative selection | 10520437 | 52286811 | 52286834 | 12 | - | 28162770 | SKM1 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | -0.04018186807153881 | [56] | [97] | 0 | hSpCas9 | negative selection | 10520438 | 52287310 | 52287333 | 12 | - | 28162770 | SKM1 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | -0.8585275740471197 | [39] | [38] | -6 | hSpCas9 | negative selection | 10520439 | 52288121 | 52288144 | 12 | + | 28162770 | SKM1 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.3516463894630244 | [128] | [290] | 3 | hSpCas9 | negative selection | 10520440 | 52288035 | 52288058 | 12 | + | 28162770 | SKM1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.8340439007606333 | [197] | [623] | 7 | hSpCas9 | negative selection | 10520441 | 52286334 | 52286357 | 12 | - | 28162770 | SKM1 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.8220016980220054 | [47] | [47] | -6 | hSpCas9 | negative selection | 10520442 | 52286434 | 52286457 | 12 | + | 28162770 | SKM1 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.19751083311421216 | [71] | [110] | -2 | hSpCas9 | negative selection | 10520443 | 52287616 | 52287639 | 12 | - | 28162770 | SKM1 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 1.5845041676357214 | [52] | [280] | 9 | hSpCas9 | negative selection | 10689800 | 52286386 | 52286409 | 12 | - | 28162770 | SKM1 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.6726240739837789 | [54] | [60] | -5 | hSpCas9 | negative selection | 10689801 | 52291455 | 52291478 | 12 | - | 28162770 | SKM1 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.29347551939793054 | [53] | [116] | 3 | hSpCas9 | negative selection | 10689802 | 52291439 | 52291462 | 12 | - | 28162770 | SKM1 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.2633897932086392 | [81] | [173] | 2 | hSpCas9 | negative selection | 10689803 | 52286811 | 52286834 | 12 | - | 28162770 | SKM1 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | -0.04018186807153881 | [56] | [97] | 0 | hSpCas9 | negative selection | 10689804 | 52287310 | 52287333 | 12 | - | 28162770 | SKM1 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | -0.8585275740471197 | [39] | [38] | -6 | hSpCas9 | negative selection | 10689805 | 52288121 | 52288144 | 12 | + | 28162770 | SKM1 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.3516463894630244 | [128] | [290] | 3 | hSpCas9 | negative selection | 10689806 | 52288035 | 52288058 | 12 | + | 28162770 | SKM1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.8340439007606333 | [197] | [623] | 7 | hSpCas9 | negative selection | 10689807 | 52286334 | 52286357 | 12 | - | 28162770 | SKM1 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.8220016980220054 | [47] | [47] | -6 | hSpCas9 | negative selection | 10689808 | 52286434 | 52286457 | 12 | + | 28162770 | SKM1 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.19751083311421216 | [71] | [110] | -2 | hSpCas9 | negative selection | 10689809 | 52287616 | 52287639 | 12 | - | 28162770 | PL21 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.4162730453540856 | [197] | [114] | 3 | hSpCas9 | negative selection | 10859166 | 52286386 | 52286409 | 12 | - | 28162770 | PL21 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -1.7540566958975552 | [216] | [27] | -8 | hSpCas9 | negative selection | 10859167 | 52291455 | 52291478 | 12 | - | 28162770 | PL21 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.6607739802082747 | [217] | [149] | 6 | hSpCas9 | negative selection | 10859168 | 52291439 | 52291462 | 12 | - | 28162770 | PL21 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | -0.23759693304865803 | [362] | [133] | -2 | hSpCas9 | negative selection | 10859169 | 52286811 | 52286834 | 12 | - | 28162770 | PL21 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.4296214606120874 | [231] | [135] | 4 | hSpCas9 | negative selection | 10859170 | 52287310 | 52287333 | 12 | - | 28162770 | PL21 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.8665297145543225 | [154] | [122] | 7 | hSpCas9 | negative selection | 10859171 | 52288121 | 52288144 | 12 | + | 28162770 | PL21 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | -0.6387055936960998 | [439] | [122] | -4 | hSpCas9 | negative selection | 10859172 | 52288035 | 52288058 | 12 | + | 28162770 | PL21 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 1.175430627317267 | [529] | [520] | 8 | hSpCas9 | negative selection | 10859173 | 52286334 | 52286357 | 12 | - | 28162770 | PL21 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | 0.21875529265666727 | [153] | [77] | 2 | hSpCas9 | negative selection | 10859174 | 52286434 | 52286457 | 12 | + | 28162770 | PL21 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.7645273123983991 | [241] | [61] | -5 | hSpCas9 | negative selection | 10859175 | 52287616 | 52287639 | 12 | - | 28162770 | P31FUJ | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.5022255855103349 | [148] | [247] | 5 | hSpCas9 | negative selection | 11028532 | 52286386 | 52286409 | 12 | - | 28162770 | P31FUJ | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.4409881332525528 | [319] | [276] | -4 | hSpCas9 | negative selection | 11028533 | 52291455 | 52291478 | 12 | - | 28162770 | P31FUJ | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | -0.11432873453452302 | [221] | [240] | -1 | hSpCas9 | negative selection | 11028534 | 52291439 | 52291462 | 12 | - | 28162770 | P31FUJ | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | -0.41701992272459815 | [316] | [278] | -4 | hSpCas9 | negative selection | 11028535 | 52286811 | 52286834 | 12 | - | 28162770 | P31FUJ | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.5361922439444654 | [195] | [333] | 6 | hSpCas9 | negative selection | 11028536 | 52287310 | 52287333 | 12 | - | 28162770 | P31FUJ | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | -0.1000469955626071 | [165] | [181] | -1 | hSpCas9 | negative selection | 11028537 | 52288121 | 52288144 | 12 | + | 28162770 | P31FUJ | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.34613650867900736 | [479] | [716] | 4 | hSpCas9 | negative selection | 11028538 | 52288035 | 52288058 | 12 | + | 28162770 | P31FUJ | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.179000551265164 | [892] | [1187] | 1 | hSpCas9 | negative selection | 11028539 | 52286334 | 52286357 | 12 | - | 28162770 | P31FUJ | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.21997816405679504 | [223] | [225] | -2 | hSpCas9 | negative selection | 11028540 | 52286434 | 52286457 | 12 | + | 28162770 | P31FUJ | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.45582093140029334 | [383] | [328] | -4 | hSpCas9 | negative selection | 11028541 | 52287616 | 52287639 | 12 | - | 28162770 | OCIAML5 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.3640668600007687 | [98] | [229] | 3 | hSpCas9 | negative selection | 11197898 | 52286386 | 52286409 | 12 | - | 28162770 | OCIAML5 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.6426132052350472 | [159] | [184] | -4 | hSpCas9 | negative selection | 11197899 | 52291455 | 52291478 | 12 | - | 28162770 | OCIAML5 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | -0.4929854775591686 | [137] | [176] | -3 | hSpCas9 | negative selection | 11197900 | 52291439 | 52291462 | 12 | - | 28162770 | OCIAML5 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | -0.32050032712093335 | [210] | [304] | -2 | hSpCas9 | negative selection | 11197901 | 52286811 | 52286834 | 12 | - | 28162770 | OCIAML5 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | -0.3958373842650438 | [163] | [224] | -3 | hSpCas9 | negative selection | 11197902 | 52287310 | 52287333 | 12 | - | 28162770 | OCIAML5 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.648917537217806 | [111] | [316] | 5 | hSpCas9 | negative selection | 11197903 | 52288121 | 52288144 | 12 | + | 28162770 | OCIAML5 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.2622661046149979 | [387] | [839] | 2 | hSpCas9 | negative selection | 11197904 | 52288035 | 52288058 | 12 | + | 28162770 | OCIAML5 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.802317330814639 | [425] | [1340] | 7 | hSpCas9 | negative selection | 11197905 | 52286334 | 52286357 | 12 | - | 28162770 | OCIAML5 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | 0.06689685704509649 | [118] | [224] | 0 | hSpCas9 | negative selection | 11197906 | 52286434 | 52286457 | 12 | + | 28162770 | OCIAML5 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.3468312626135751 | [185] | [263] | -2 | hSpCas9 | negative selection | 11197907 | 52287616 | 52287639 | 12 | - | 28162770 | EOL1 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.3567750321468935 | [291] | [196] | 3 | hSpCas9 | negative selection | 11367264 | 52286386 | 52286409 | 12 | - | 28162770 | EOL1 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.5618989885095531 | [282] | [100] | -4 | hSpCas9 | negative selection | 11367265 | 52291455 | 52291478 | 12 | - | 28162770 | EOL1 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.7781912412666265 | [424] | [383] | 7 | hSpCas9 | negative selection | 11367266 | 52291439 | 52291462 | 12 | - | 28162770 | EOL1 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 1.045761358539615 | [501] | [545] | 8 | hSpCas9 | negative selection | 11367267 | 52286811 | 52286834 | 12 | - | 28162770 | EOL1 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.8933531499669403 | [373] | [365] | 7 | hSpCas9 | negative selection | 11367268 | 52287310 | 52287333 | 12 | - | 28162770 | EOL1 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 1.3078764111220402 | [252] | [329] | 9 | hSpCas9 | negative selection | 11367269 | 52288121 | 52288144 | 12 | + | 28162770 | EOL1 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.16293517091519394 | [550] | [324] | 1 | hSpCas9 | negative selection | 11367270 | 52288035 | 52288058 | 12 | + | 28162770 | EOL1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.2903240508100524 | [848] | [546] | 2 | hSpCas9 | negative selection | 11367271 | 52286334 | 52286357 | 12 | - | 28162770 | EOL1 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.34630613872255867 | [221] | [91] | -3 | hSpCas9 | negative selection | 11367272 | 52286434 | 52286457 | 12 | + | 28162770 | EOL1 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.19999732636776874 | [265] | [121] | -1 | hSpCas9 | negative selection | 11367273 | 52287616 | 52287639 | 12 | - | 28162770 | MOLM13 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 1.054651876311945 | [266] | [400] | 7 | hSpCas9 | negative selection | 11536630 | 52286386 | 52286409 | 12 | - | 28162770 | MOLM13 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | 0.3153674263637116 | [308] | [277] | 2 | hSpCas9 | negative selection | 11536631 | 52291455 | 52291478 | 12 | - | 28162770 | MOLM13 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.9306800122717906 | [311] | [429] | 7 | hSpCas9 | negative selection | 11536632 | 52291439 | 52291462 | 12 | - | 28162770 | MOLM13 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.48022018345529816 | [465] | [469] | 3 | hSpCas9 | negative selection | 11536633 | 52286811 | 52286834 | 12 | - | 28162770 | MOLM13 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 2.5136490429272618 | [255] | [1056] | 9 | hSpCas9 | negative selection | 11536634 | 52287310 | 52287333 | 12 | - | 28162770 | MOLM13 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 1.0451983097222999 | [188] | [281] | 7 | hSpCas9 | negative selection | 11536635 | 52288121 | 52288144 | 12 | + | 28162770 | MOLM13 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.4989676927300224 | [596] | [609] | 4 | hSpCas9 | negative selection | 11536636 | 52288035 | 52288058 | 12 | + | 28162770 | MOLM13 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.055968336273834574 | [1078] | [810] | 0 | hSpCas9 | negative selection | 11536637 | 52286334 | 52286357 | 12 | - | 28162770 | MOLM13 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.9007552122498139 | [203] | [78] | -5 | hSpCas9 | negative selection | 11536638 | 52286434 | 52286457 | 12 | + | 28162770 | MOLM13 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.7913534451268409 | [303] | [126] | -4 | hSpCas9 | negative selection | 11536639 | 52287616 | 52287639 | 12 | - | 28162770 | HEL | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 1.0059551353783514 | [247] | [318] | 8 | hSpCas9 | negative selection | 11705996 | 52286386 | 52286409 | 12 | - | 28162770 | HEL | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.19152396352076417 | [229] | [128] | -1 | hSpCas9 | negative selection | 11705997 | 52291455 | 52291478 | 12 | - | 28162770 | HEL | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.8309425671609781 | [243] | [277] | 7 | hSpCas9 | negative selection | 11705998 | 52291439 | 52291462 | 12 | - | 28162770 | HEL | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.9554664858307739 | [408] | [507] | 8 | hSpCas9 | negative selection | 11705999 | 52286811 | 52286834 | 12 | - | 28162770 | HEL | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 1.3416292086205486 | [214] | [348] | 9 | hSpCas9 | negative selection | 11706000 | 52287310 | 52287333 | 12 | - | 28162770 | HEL | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.4399219490006699 | [182] | [158] | 3 | hSpCas9 | negative selection | 11706001 | 52288121 | 52288144 | 12 | + | 28162770 | HEL | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.07703823343983363 | [557] | [376] | 0 | hSpCas9 | negative selection | 11706002 | 52288035 | 52288058 | 12 | + | 28162770 | HEL | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.1431678225098454 | [737] | [521] | 1 | hSpCas9 | negative selection | 11706003 | 52286334 | 52286357 | 12 | - | 28162770 | HEL | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.4543598561047246 | [168] | [78] | -3 | hSpCas9 | negative selection | 11706004 | 52286434 | 52286457 | 12 | + | 28162770 | HEL | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.4099026477408728 | [306] | [147] | -3 | hSpCas9 | negative selection | 11706005 | 52287616 | 52287639 | 12 | - | 28162770 | MV411 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.2807576239828017 | [213] | [218] | 2 | hSpCas9 | negative selection | 11875362 | 52286386 | 52286409 | 12 | - | 28162770 | MV411 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | 0.5580798381236225 | [153] | [190] | 5 | hSpCas9 | negative selection | 11875363 | 52291455 | 52291478 | 12 | - | 28162770 | MV411 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.5754062478274372 | [285] | [358] | 5 | hSpCas9 | negative selection | 11875364 | 52291439 | 52291462 | 12 | - | 28162770 | MV411 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.6156301866019517 | [312] | [403] | 5 | hSpCas9 | negative selection | 11875365 | 52286811 | 52286834 | 12 | - | 28162770 | MV411 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.5402193000106212 | [199] | [244] | 5 | hSpCas9 | negative selection | 11875366 | 52287310 | 52287333 | 12 | - | 28162770 | MV411 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | -0.049828489870317905 | [144] | [117] | 0 | hSpCas9 | negative selection | 11875367 | 52288121 | 52288144 | 12 | + | 28162770 | MV411 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.3774363678123285 | [402] | [440] | 3 | hSpCas9 | negative selection | 11875368 | 52288035 | 52288058 | 12 | + | 28162770 | MV411 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.5514437376728756 | [566] | [699] | 5 | hSpCas9 | negative selection | 11875369 | 52286334 | 52286357 | 12 | - | 28162770 | MV411 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | 0.15507353263411566 | [128] | [120] | 1 | hSpCas9 | negative selection | 11875370 | 52286434 | 52286457 | 12 | + | 28162770 | MV411 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.758463050656909 | [244] | [121] | -5 | hSpCas9 | negative selection | 11875371 | 52287616 | 52287639 | 12 | - | 28162770 | MONOMAC1 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.3685603287946714 | [99] | [147] | 3 | hSpCas9 | negative selection | 12044728 | 52286386 | 52286409 | 12 | - | 28162770 | MONOMAC1 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -1.4664975220527805 | [134] | [55] | -8 | hSpCas9 | negative selection | 12044729 | 52291455 | 52291478 | 12 | - | 28162770 | MONOMAC1 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.3909854534106606 | [156] | [235] | 4 | hSpCas9 | negative selection | 12044730 | 52291439 | 52291462 | 12 | - | 28162770 | MONOMAC1 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.6244250211934259 | [188] | [333] | 6 | hSpCas9 | negative selection | 12044731 | 52286811 | 52286834 | 12 | - | 28162770 | MONOMAC1 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.288389980110688 | [149] | [209] | 3 | hSpCas9 | negative selection | 12044732 | 52287310 | 52287333 | 12 | - | 28162770 | MONOMAC1 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 0.2002986504858313 | [81] | [107] | 2 | hSpCas9 | negative selection | 12044733 | 52288121 | 52288144 | 12 | + | 28162770 | MONOMAC1 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | -0.10633853676781624 | [261] | [278] | -1 | hSpCas9 | negative selection | 12044734 | 52288035 | 52288058 | 12 | + | 28162770 | MONOMAC1 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.7200384422344475 | [366] | [692] | 7 | hSpCas9 | negative selection | 12044735 | 52286334 | 52286357 | 12 | - | 28162770 | MONOMAC1 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.397335497545385 | [107] | [93] | -3 | hSpCas9 | negative selection | 12044736 | 52286434 | 52286457 | 12 | + | 28162770 | MONOMAC1 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.3490399405046036 | [149] | [134] | -3 | hSpCas9 | negative selection | 12044737 | 52287616 | 52287639 | 12 | - | 28162770 | OCIAML2 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | 0.38181298634398086 | [53] | [389] | 3 | hSpCas9 | negative selection | 12214094 | 52286386 | 52286409 | 12 | - | 28162770 | OCIAML2 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | 0.036330163477721986 | [37] | [215] | 0 | hSpCas9 | negative selection | 12214095 | 52291455 | 52291478 | 12 | - | 28162770 | OCIAML2 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | 0.9016033514932666 | [30] | [320] | 8 | hSpCas9 | negative selection | 12214096 | 52291439 | 52291462 | 12 | - | 28162770 | OCIAML2 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.09140627862948736 | [73] | [436] | 0 | hSpCas9 | negative selection | 12214097 | 52286811 | 52286834 | 12 | - | 28162770 | OCIAML2 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 0.39231742277876036 | [39] | [290] | 4 | hSpCas9 | negative selection | 12214098 | 52287310 | 52287333 | 12 | - | 28162770 | OCIAML2 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | 1.0762646346454756 | [15] | [186] | 8 | hSpCas9 | negative selection | 12214099 | 52288121 | 52288144 | 12 | + | 28162770 | OCIAML2 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | -0.11045426099783584 | [66] | [343] | -1 | hSpCas9 | negative selection | 12214100 | 52288035 | 52288058 | 12 | + | 28162770 | OCIAML2 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.7364343126131982 | [97] | [904] | 7 | hSpCas9 | negative selection | 12214101 | 52286334 | 52286357 | 12 | - | 28162770 | OCIAML2 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.158685818927421 | [28] | [143] | -1 | hSpCas9 | negative selection | 12214102 | 52286434 | 52286457 | 12 | + | 28162770 | OCIAML2 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.5176273047793307 | [38] | [150] | -4 | hSpCas9 | negative selection | 12214103 | 52287616 | 52287639 | 12 | - | 28162770 | OCIAML3 | viability | GATCCAAAGGCTGACGGCCGAGG | KRT81 | ENSG00000205426 | -0.1789701410453194 | [56] | [151] | -1 | hSpCas9 | negative selection | 12383460 | 52286386 | 52286409 | 12 | - | 28162770 | OCIAML3 | viability | TCCGTGCAACGGGAACGTGGCGG | KRT81 | ENSG00000205426 | -0.8207785021711853 | [54] | [93] | -6 | hSpCas9 | negative selection | 12383461 | 52291455 | 52291478 | 12 | - | 28162770 | OCIAML3 | viability | TCCAGGAGGATCATGACCTGCGG | KRT81 | ENSG00000205426 | -0.3761026099800292 | [45] | [106] | -3 | hSpCas9 | negative selection | 12383462 | 52291439 | 52291462 | 12 | - | 28162770 | OCIAML3 | viability | CCTGCGGATCAGGATTTGGTGGG | KRT81 | ENSG00000205426 | 0.13223154724898445 | [80] | [267] | 1 | hSpCas9 | negative selection | 12383463 | 52286811 | 52286834 | 12 | - | 28162770 | OCIAML3 | viability | TTTGCCCTCAGGCTATGTGAAGG | KRT81 | ENSG00000205426 | 1.3722040462195535 | [53] | [421] | 9 | hSpCas9 | negative selection | 12383464 | 52287310 | 52287333 | 12 | - | 28162770 | OCIAML3 | viability | TTCTCTTCAGAACTCCAAGCTGG | KRT81 | ENSG00000205426 | -0.1554346265845301 | [37] | [102] | -1 | hSpCas9 | negative selection | 12383465 | 52288121 | 52288144 | 12 | + | 28162770 | OCIAML3 | viability | AGATGTGCGACTGGAGAATGAGG | KRT81 | ENSG00000205426 | 0.27130874243081293 | [114] | [418] | 2 | hSpCas9 | negative selection | 12383466 | 52288035 | 52288058 | 12 | + | 28162770 | OCIAML3 | viability | GTCATACTGTGCCTTAATCTCGG | KRT81 | ENSG00000205426 | 0.899032370955954 | [161] | [911] | 7 | hSpCas9 | negative selection | 12383467 | 52286334 | 52286357 | 12 | - | 28162770 | OCIAML3 | viability | CAATTGAACACCACCTGCGGAGG | KRT81 | ENSG00000205426 | -0.09575677279633782 | [39] | [112] | 0 | hSpCas9 | negative selection | 12383468 | 52286434 | 52286457 | 12 | + | 28162770 | OCIAML3 | viability | GCCGGGAGCCTGACACGCAGAGG | KRT81 | ENSG00000205426 | -0.553593371878255 | [87] | [180] | -4 | hSpCas9 | negative selection | 12383469 |