Crispr
Gene Info
- Species:Human (Homo sapiens)
- GeneID:3890
- Symbol:KRT84
- Description:keratin 84
DataSource:
http://genomecrispr.dkfz.de/#!/results/KRT84
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| Start | The end | chr | strand | pubmed | cellline | condition | sequence | symbol | ensg | log2fc | rc_initial | rc_final | effect | cas | screentype | index |
52378277 | 52378300 | 12 | + | 26627737 | DLD1 | viability | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | -0.8588307671801788 | [455] | [115,44,73] | -7 | hSpCas9 | negative selection | 784228 | 52378277 | 52378300 | 12 | + | 26627737 | GBM cells | viability after 5 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.6132416653721602 | [166] | [147,125] | 8 | hSpCas9 | negative selection | 866543 | 52378277 | 52378300 | 12 | + | 26627737 | GBM cells | viability after 13 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.08192410916700965 | [166] | [112,81] | 1 | hSpCas9 | negative selection | 948858 | 52378277 | 52378300 | 12 | + | 26627737 | GBM cells | viability after 21 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.010475874321897782 | [166] | [93,88] | 0 | hSpCas9 | negative selection | 1031173 | 52378277 | 52378300 | 12 | + | 26627737 | RPE1 | viability after 9 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | -0.49920326072179494 | [923] | [191,220] | -4 | hSpCas9 | negative selection | 1113488 | 52378277 | 52378300 | 12 | + | 26627737 | RPE1 | viability after 12 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | -0.5638110030365537 | [923] | [199,133] | -4 | hSpCas9 | negative selection | 1195803 | 52378277 | 52378300 | 12 | + | 26627737 | RPE1 | viability after 15 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | -1.1200663689732184 | [923] | [105,133] | -6 | hSpCas9 | negative selection | 1278118 | 52378277 | 52378300 | 12 | + | 26627737 | RPE1 | viability after 18 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | -0.9118968503814953 | [923] | [147,115] | -5 | hSpCas9 | negative selection | 1360433 | 52378277 | 52378300 | 12 | + | 26627737 | HeLa | viability after 8 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 1.9732160666835359 | [119] | [379,222,60] | 9 | hSpCas9 | negative selection | 1442748 | 52378277 | 52378300 | 12 | + | 26627737 | HeLa | viability after 12 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 1.6498112915461058 | [119] | [236,100,136] | 9 | hSpCas9 | negative selection | 1525063 | 52378277 | 52378300 | 12 | + | 26627737 | HeLa | viability after 15 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 2.0309153925872048 | [119] | [263,195,132] | 9 | hSpCas9 | negative selection | 1607378 | 52378277 | 52378300 | 12 | + | 26627737 | HeLa | viability after 18 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 2.037698473087921 | [119] | [183,155,132] | 9 | hSpCas9 | negative selection | 1689693 | 52378277 | 52378300 | 12 | + | 26627737 | HCT116 | viability after 6 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 2.1991003560184215 | [84] | [168,1] | 9 | hSpCas9 | negative selection | 1772008 | 52378277 | 52378300 | 12 | + | 26627737 | HCT116 | viability after 8 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 1.3425790042737122 | [109] | [162,200,97] | 9 | hSpCas9 | negative selection | 1854323 | 52378277 | 52378300 | 12 | + | 26627737 | HCT116 | viability after 9 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 2.0403370997977204 | [84] | [170,31] | 9 | hSpCas9 | negative selection | 1936638 | 52378277 | 52378300 | 12 | + | 26627737 | HCT116 | viability after 12 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.8256374870606811 | [109] | [104,137,64] | 7 | hSpCas9 | negative selection | 2018953 | 52378277 | 52378300 | 12 | + | 26627737 | HCT116 | viability after 15 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 1.2389695699812695 | [109] | [246,126,85] | 8 | hSpCas9 | negative selection | 2101268 | 52378277 | 52378300 | 12 | + | 26627737 | HCT116 | viability after 18 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 1.0074023991719607 | [109] | [100,183,26] | 7 | hSpCas9 | negative selection | 2183583 | 52378277 | 52378300 | 12 | + | 27869803 | HPAFII | viability after 27 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.18534802646551496 | [157] | [136,58,NaN] | 1 | hSpCas9 | negative selection | 9547228 | 52378277 | 52378300 | 12 | + | 27869803 | HPAFII | viability after 15 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.8045028747589857 | [157] | [393,235,NaN] | 8 | hSpCas9 | negative selection | 9629677 | 52378277 | 52378300 | 12 | + | 27869803 | ASPC1 | viability after 36 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.1267831355857439 | [451] | [58,277,165] | 1 | hSpCas9 | negative selection | 9712126 | 52378277 | 52378300 | 12 | + | 27869803 | PATU8988S | viability after 35 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | -0.028373266835538757 | [422] | [186,146,NaN] | 0 | hSpCas9 | negative selection | 9794575 | 52378277 | 52378300 | 12 | + | 27869803 | PATU8988S | viability after 31 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.08775983362057915 | [422] | [213,134,NaN] | 1 | hSpCas9 | negative selection | 9877024 | 52378277 | 52378300 | 12 | + | 27869803 | HPAFII | viability after 35 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.9460567591759015 | [157] | [123,187,NaN] | 6 | hSpCas9 | negative selection | 9959473 | 52378277 | 52378300 | 12 | + | 27869803 | HPAFII | viability after 31 days | GACGCTGCTGCTACCTGAGAAGG | KRT84 | ENSG00000161849 | 0.8654911785475886 | [157] | [173,147,NaN] | 6 | hSpCas9 | negative selection | 10041922 |