Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3891
• Symbol:KRT85
• Description:keratin 85

DataSource: http://genomecrispr.dkfz.de/#!/results/KRT85

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
52367265	52367288	12	-	26472758	Jiyoye	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	0.3002601775893614	[41]	[38]	2	hSpCas9	negative selection	86769
52364067	52364090	12	-	26472758	Jiyoye	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	-2.6459359549536887	[165]	[19]	-9	hSpCas9	negative selection	86770
52365089	52365112	12	+	26472758	Jiyoye	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	1.533552667275429	[70]	[154]	8	hSpCas9	negative selection	86771
52364124	52364147	12	-	26472758	Jiyoye	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.11365678179556715	[230]	[160]	-1	hSpCas9	negative selection	86772
52362324	52362347	12	-	26472758	Jiyoye	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	0.12819943180305787	[90]	[74]	1	hSpCas9	negative selection	86773
52367194	52367217	12	+	26472758	Jiyoye	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.7546148026339067	[212]	[270]	5	hSpCas9	negative selection	86774
52365061	52365084	12	+	26472758	Jiyoye	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.09347083328180705	[323]	[228]	0	hSpCas9	negative selection	86775
52364318	52364341	12	+	26472758	Jiyoye	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.029290880644495698	[229]	[176]	0	hSpCas9	negative selection	86776
52364103	52364126	12	-	26472758	Jiyoye	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-1.5128563137907114	[192]	[50]	-7	hSpCas9	negative selection	86777
52364089	52364112	12	+	26472758	Jiyoye	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.45920005436393113	[236]	[129]	-3	hSpCas9	negative selection	86778
52367265	52367288	12	-	26472758	KBM7	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-0.8158322856647349	[189,227]	[44,66]	-6	hSpCas9	negative selection	277887
52364067	52364090	12	-	26472758	KBM7	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	-0.41560617009917256	[360,304]	[117,115]	-4	hSpCas9	negative selection	277888
52365089	52365112	12	+	26472758	KBM7	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.862585246244957	[727,540]	[764,332]	8	hSpCas9	negative selection	277889
52364124	52364147	12	-	26472758	KBM7	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	0.6241029465322231	[294,209]	[185,175]	6	hSpCas9	negative selection	277890
52362324	52362347	12	-	26472758	KBM7	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-0.5071132445560071	[603,421]	[186,149]	-4	hSpCas9	negative selection	277891
52367194	52367217	12	+	26472758	KBM7	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.04306895457325188	[1466,928]	[577,499]	0	hSpCas9	negative selection	277892
52365061	52365084	12	+	26472758	KBM7	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.24668126615027086	[1193,1193]	[445,868]	2	hSpCas9	negative selection	277893
52364318	52364341	12	+	26472758	KBM7	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.8225715443561802	[787,848]	[685,686]	8	hSpCas9	negative selection	277894
52364103	52364126	12	-	26472758	KBM7	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	0.6062319500958391	[456,288]	[221,297]	6	hSpCas9	negative selection	277895
52364089	52364112	12	+	26472758	KBM7	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.10030707894979812	[617,553]	[329,263]	1	hSpCas9	negative selection	277896
52367265	52367288	12	-	26472758	Raji	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	1.3127024433511059	[84]	[48]	9	hSpCas9	negative selection	469005
52364067	52364090	12	-	26472758	Raji	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.02689361751323166	[257]	[60]	0	hSpCas9	negative selection	469006
52365089	52365112	12	+	26472758	Raji	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.6138440624160381	[213]	[75]	6	hSpCas9	negative selection	469007
52364124	52364147	12	-	26472758	Raji	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.43318484598910306	[255]	[43]	-4	hSpCas9	negative selection	469008
52362324	52362347	12	-	26472758	Raji	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-0.5968778937199013	[188]	[28]	-5	hSpCas9	negative selection	469009
52367194	52367217	12	+	26472758	Raji	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.8904829175506385	[436]	[187]	7	hSpCas9	negative selection	469010
52365061	52365084	12	+	26472758	Raji	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.0013821815167109897	[606]	[140]	0	hSpCas9	negative selection	469011
52364318	52364341	12	+	26472758	Raji	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	-0.3903943949131805	[609]	[107]	-3	hSpCas9	negative selection	469012
52364103	52364126	12	-	26472758	Raji	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.05407988732051669	[254]	[56]	0	hSpCas9	negative selection	469013
52364089	52364112	12	+	26472758	Raji	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.6249907682929909	[284]	[101]	6	hSpCas9	negative selection	469014
52367265	52367288	12	-	26472758	K562	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	0.6678196998799173	[128]	[172]	5	hSpCas9	negative selection	660123
52364067	52364090	12	-	26472758	K562	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.5383087741079462	[238]	[292]	4	hSpCas9	negative selection	660124
52365089	52365112	12	+	26472758	K562	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.20782157400287615	[518]	[505]	1	hSpCas9	negative selection	660125
52364124	52364147	12	-	26472758	K562	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	0.5224034749662121	[319]	[387]	4	hSpCas9	negative selection	660126
52362324	52362347	12	-	26472758	K562	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-1.2181076973937162	[349]	[126]	-6	hSpCas9	negative selection	660127
52367194	52367217	12	+	26472758	K562	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.6160998577509089	[683]	[884]	5	hSpCas9	negative selection	660128
52365061	52365084	12	+	26472758	K562	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.18600204144112498	[881]	[846]	1	hSpCas9	negative selection	660129
52364318	52364341	12	+	26472758	K562	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.4412760568957572	[854]	[979]	3	hSpCas9	negative selection	660130
52364103	52364126	12	-	26472758	K562	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.17459862252494207	[241]	[180]	-1	hSpCas9	negative selection	660131
52364089	52364112	12	+	26472758	K562	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.05084914149575284	[445]	[389]	0	hSpCas9	negative selection	660132
52360936	52360959	12	-	26627737	DLD1	viability	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.6653195365598851	[515]	[195,56,56]	-6	hSpCas9	negative selection	784222
52362459	52362482	12	-	26627737	DLD1	viability	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.4243044261956975	[852]	[303,460,318]	4	hSpCas9	negative selection	784223
52364089	52364112	12	+	26627737	DLD1	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.5483566312388524	[531]	[336,230,171]	5	hSpCas9	negative selection	784224
52364157	52364180	12	-	26627737	DLD1	viability	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.763504888144565	[362]	[230,180,168]	7	hSpCas9	negative selection	784225
52365061	52365084	12	+	26627737	DLD1	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.3403153826845875	[1144]	[527,479,365]	3	hSpCas9	negative selection	784226
52367185	52367208	12	-	26627737	DLD1	viability	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-0.020230974631591823	[456]	[133,165,125]	0	hSpCas9	negative selection	784227
52360936	52360959	12	-	26627737	GBM cells	viability after 5 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.3099515555150406	[229]	[98,99]	-5	hSpCas9	negative selection	866537
52362459	52362482	12	-	26627737	GBM cells	viability after 5 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.7342831731128865	[356]	[331,304]	8	hSpCas9	negative selection	866538
52364089	52364112	12	+	26627737	GBM cells	viability after 5 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.12632437098875804	[368]	[194,236]	2	hSpCas9	negative selection	866539
52364157	52364180	12	-	26627737	GBM cells	viability after 5 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.11189288007089712	[267]	[108,156]	-2	hSpCas9	negative selection	866540
52365061	52365084	12	+	26627737	GBM cells	viability after 5 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.43866748431316216	[694]	[216,332]	-6	hSpCas9	negative selection	866541
52367185	52367208	12	-	26627737	GBM cells	viability after 5 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	1.1231290318289513	[112]	[141,121]	9	hSpCas9	negative selection	866542
52360936	52360959	12	-	26627737	GBM cells	viability after 13 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.3429514523750969	[229]	[120,79]	-4	hSpCas9	negative selection	948852
52362459	52362482	12	-	26627737	GBM cells	viability after 13 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.4729173881340085	[356]	[366,188]	6	hSpCas9	negative selection	948853
52364089	52364112	12	+	26627737	GBM cells	viability after 13 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.01147156094337387	[368]	[235,173]	0	hSpCas9	negative selection	948854
52364157	52364180	12	-	26627737	GBM cells	viability after 13 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.4482072914741335	[267]	[220,179]	5	hSpCas9	negative selection	948855
52365061	52365084	12	+	26627737	GBM cells	viability after 13 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.5406477040053255	[694]	[320,208]	-6	hSpCas9	negative selection	948856
52367185	52367208	12	-	26627737	GBM cells	viability after 13 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.7780879551732288	[112]	[108,101]	8	hSpCas9	negative selection	948857
52360936	52360959	12	-	26627737	GBM cells	viability after 21 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.620270487909675	[229]	[97,65]	-5	hSpCas9	negative selection	1031167
52362459	52362482	12	-	26627737	GBM cells	viability after 21 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.7569783675352564	[356]	[344,311]	7	hSpCas9	negative selection	1031168
52364089	52364112	12	+	26627737	GBM cells	viability after 21 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.032158196088365454	[368]	[216,193]	0	hSpCas9	negative selection	1031169
52364157	52364180	12	-	26627737	GBM cells	viability after 21 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.7249034163348512	[267]	[248,232]	7	hSpCas9	negative selection	1031170
52365061	52365084	12	+	26627737	GBM cells	viability after 21 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.8618926218492473	[694]	[236,180]	-6	hSpCas9	negative selection	1031171
52367185	52367208	12	-	26627737	GBM cells	viability after 21 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	1.317756458304318	[112]	[163,142]	9	hSpCas9	negative selection	1031172
52360936	52360959	12	-	26627737	RPE1	viability after 9 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.027846841591746885	[480]	[194,99]	0	hSpCas9	negative selection	1113482
52362459	52362482	12	-	26627737	RPE1	viability after 9 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.607563517103185	[1662]	[777,812]	4	hSpCas9	negative selection	1113483
52364089	52364112	12	+	26627737	RPE1	viability after 9 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.16380113136151786	[1222]	[298,396]	-1	hSpCas9	negative selection	1113484
52364157	52364180	12	-	26627737	RPE1	viability after 9 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.9011564606044402	[540]	[345,277]	6	hSpCas9	negative selection	1113485
52365061	52365084	12	+	26627737	RPE1	viability after 9 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.029893031155669547	[2399]	[559,962]	0	hSpCas9	negative selection	1113486
52367185	52367208	12	-	26627737	RPE1	viability after 9 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	1.0048002311323807	[701]	[447,431]	6	hSpCas9	negative selection	1113487
52360936	52360959	12	-	26627737	RPE1	viability after 12 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.13886533791357292	[480]	[202,77]	1	hSpCas9	negative selection	1195797
52362459	52362482	12	-	26627737	RPE1	viability after 12 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.4637269353512883	[1662]	[740,483]	3	hSpCas9	negative selection	1195798
52364089	52364112	12	+	26627737	RPE1	viability after 12 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.02534514160930279	[1222]	[317,327]	0	hSpCas9	negative selection	1195799
52364157	52364180	12	-	26627737	RPE1	viability after 12 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	1.1633303017720098	[540]	[326,323]	7	hSpCas9	negative selection	1195800
52365061	52365084	12	+	26627737	RPE1	viability after 12 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.1947646898781774	[2399]	[456,675]	-1	hSpCas9	negative selection	1195801
52367185	52367208	12	-	26627737	RPE1	viability after 12 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.47499361704154813	[701]	[198,328]	3	hSpCas9	negative selection	1195802
52360936	52360959	12	-	26627737	RPE1	viability after 15 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.6281980792905496	[480]	[389,36]	4	hSpCas9	negative selection	1278112
52362459	52362482	12	-	26627737	RPE1	viability after 15 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.32791439346256146	[1662]	[647,534]	2	hSpCas9	negative selection	1278113
52364089	52364112	12	+	26627737	RPE1	viability after 15 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.7071399408437218	[1222]	[244,179]	-4	hSpCas9	negative selection	1278114
52364157	52364180	12	-	26627737	RPE1	viability after 15 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	1.5936951727964057	[540]	[326,591]	8	hSpCas9	negative selection	1278115
52365061	52365084	12	+	26627737	RPE1	viability after 15 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.3711822223877588	[2399]	[361,681]	-2	hSpCas9	negative selection	1278116
52367185	52367208	12	-	26627737	RPE1	viability after 15 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.676633445265262	[701]	[237,393]	4	hSpCas9	negative selection	1278117
52360936	52360959	12	-	26627737	RPE1	viability after 18 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.0846757006291351	[480]	[177,62]	0	hSpCas9	negative selection	1360427
52362459	52362482	12	-	26627737	RPE1	viability after 18 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.13419372251741235	[1662]	[449,537]	0	hSpCas9	negative selection	1360428
52364089	52364112	12	+	26627737	RPE1	viability after 18 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.5683412283866407	[1222]	[224,219]	-4	hSpCas9	negative selection	1360429
52364157	52364180	12	-	26627737	RPE1	viability after 18 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	1.190875343437584	[540]	[312,354]	6	hSpCas9	negative selection	1360430
52365061	52365084	12	+	26627737	RPE1	viability after 18 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.1916303211288919	[2399]	[584,904]	1	hSpCas9	negative selection	1360431
52367185	52367208	12	-	26627737	RPE1	viability after 18 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	1.3711045585479285	[701]	[432,550]	7	hSpCas9	negative selection	1360432
52360936	52360959	12	-	26627737	HeLa	viability after 8 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.31773538736510587	[304]	[142,207,141]	3	hSpCas9	negative selection	1442742
52362459	52362482	12	-	26627737	HeLa	viability after 8 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.2921782498512815	[638]	[396,268,365]	2	hSpCas9	negative selection	1442743
52364089	52364112	12	+	26627737	HeLa	viability after 8 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	1.0829348319068002	[221]	[233,294,98]	8	hSpCas9	negative selection	1442744
52364157	52364180	12	-	26627737	HeLa	viability after 8 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.4574293184368522	[618]	[145,287,146]	-4	hSpCas9	negative selection	1442745
52365061	52365084	12	+	26627737	HeLa	viability after 8 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.3665069534729084	[1070]	[417,259,414]	-4	hSpCas9	negative selection	1442746
52367185	52367208	12	-	26627737	HeLa	viability after 8 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	1.2213571067058089	[381]	[487,474,232]	8	hSpCas9	negative selection	1442747
52360936	52360959	12	-	26627737	HeLa	viability after 12 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.6455353446785356	[304]	[132,193,262]	5	hSpCas9	negative selection	1525057
52362459	52362482	12	-	26627737	HeLa	viability after 12 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.3080813331438431	[638]	[471,232,289]	2	hSpCas9	negative selection	1525058
52364089	52364112	12	+	26627737	HeLa	viability after 12 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.8765461227425362	[221]	[141,201,156]	6	hSpCas9	negative selection	1525059
52364157	52364180	12	-	26627737	HeLa	viability after 12 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.9190412579462163	[618]	[103,115,186]	-7	hSpCas9	negative selection	1525060
52365061	52365084	12	+	26627737	HeLa	viability after 12 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.4275960810975734	[1070]	[360,273,358]	-4	hSpCas9	negative selection	1525061
52367185	52367208	12	-	26627737	HeLa	viability after 12 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.6189962091948065	[381]	[213,322,180]	5	hSpCas9	negative selection	1525062
52360936	52360959	12	-	26627737	HeLa	viability after 15 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.034777831421715755	[304]	[115,86,182]	0	hSpCas9	negative selection	1607372
52362459	52362482	12	-	26627737	HeLa	viability after 15 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.004247535284075954	[638]	[152,286,350]	0	hSpCas9	negative selection	1607373
52364089	52364112	12	+	26627737	HeLa	viability after 15 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.7685859307323972	[221]	[112,260,82]	6	hSpCas9	negative selection	1607374
52364157	52364180	12	-	26627737	HeLa	viability after 15 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.9075940484490165	[618]	[46,175,184]	-7	hSpCas9	negative selection	1607375
52365061	52365084	12	+	26627737	HeLa	viability after 15 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.42445313038077304	[1070]	[238,444,288]	-4	hSpCas9	negative selection	1607376
52367185	52367208	12	-	26627737	HeLa	viability after 15 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.764906369261351	[381]	[282,299,204]	6	hSpCas9	negative selection	1607377
52360936	52360959	12	-	26627737	HeLa	viability after 18 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.003758883860162432	[304]	[70,73,182]	0	hSpCas9	negative selection	1689687
52362459	52362482	12	-	26627737	HeLa	viability after 18 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	-0.0008006466883971886	[638]	[102,234,350]	0	hSpCas9	negative selection	1689688
52364089	52364112	12	+	26627737	HeLa	viability after 18 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.7525469558878295	[221]	[70,217,82]	6	hSpCas9	negative selection	1689689
52364157	52364180	12	-	26627737	HeLa	viability after 18 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.9215833634967967	[618]	[31,141,184]	-7	hSpCas9	negative selection	1689690
52365061	52365084	12	+	26627737	HeLa	viability after 18 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.40932442147339687	[1070]	[160,375,288]	-4	hSpCas9	negative selection	1689691
52367185	52367208	12	-	26627737	HeLa	viability after 18 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.7976233840398307	[381]	[193,257,204]	6	hSpCas9	negative selection	1689692
52360936	52360959	12	-	26627737	HCT116	viability after 6 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-2.0495088717277086	[463]	[25,12]	-8	hSpCas9	negative selection	1772002
52362459	52362482	12	-	26627737	HCT116	viability after 6 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.6089685240653966	[1082]	[385,189]	3	hSpCas9	negative selection	1772003
52364089	52364112	12	+	26627737	HCT116	viability after 6 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.5304841547164838	[1059]	[464,116]	3	hSpCas9	negative selection	1772004
52364157	52364180	12	-	26627737	HCT116	viability after 6 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	1.6768052952159325	[375]	[139,215]	8	hSpCas9	negative selection	1772005
52365061	52365084	12	+	26627737	HCT116	viability after 6 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.7821077440992612	[1292]	[248,404]	4	hSpCas9	negative selection	1772006
52367185	52367208	12	-	26627737	HCT116	viability after 6 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.3491151674694438	[685]	[186,109]	2	hSpCas9	negative selection	1772007
52360936	52360959	12	-	26627737	HCT116	viability after 8 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-1.3467848014738657	[533]	[82,107,154]	-9	hSpCas9	negative selection	1854317
52362459	52362482	12	-	26627737	HCT116	viability after 8 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.3066715853546472	[422]	[205,335,320]	3	hSpCas9	negative selection	1854318
52364089	52364112	12	+	26627737	HCT116	viability after 8 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.2484227059894307	[326]	[195,164,279]	2	hSpCas9	negative selection	1854319
52364157	52364180	12	-	26627737	HCT116	viability after 8 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.09296651137116113	[423]	[203,159,291]	-1	hSpCas9	negative selection	1854320
52365061	52365084	12	+	26627737	HCT116	viability after 8 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.2763091950928973	[764]	[360,465,218]	-3	hSpCas9	negative selection	1854321
52367185	52367208	12	-	26627737	HCT116	viability after 8 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.06657116006198682	[434]	[136,361,251]	0	hSpCas9	negative selection	1854322
52360936	52360959	12	-	26627737	HCT116	viability after 9 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.662266588422447	[463]	[127,38]	-5	hSpCas9	negative selection	1936632
52362459	52362482	12	-	26627737	HCT116	viability after 9 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.3225453547778101	[1082]	[326,388]	2	hSpCas9	negative selection	1936633
52364089	52364112	12	+	26627737	HCT116	viability after 9 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.5647063738875358	[1059]	[402,430]	4	hSpCas9	negative selection	1936634
52364157	52364180	12	-	26627737	HCT116	viability after 9 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.6715164974924945	[375]	[279,64]	5	hSpCas9	negative selection	1936635
52365061	52365084	12	+	26627737	HCT116	viability after 9 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.9967679665260354	[1292]	[674,699]	7	hSpCas9	negative selection	1936636
52367185	52367208	12	-	26627737	HCT116	viability after 9 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.02668842873066138	[685]	[137,224]	0	hSpCas9	negative selection	1936637
52360936	52360959	12	-	26627737	HCT116	viability after 12 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-1.2381866623770195	[533]	[80,109,168]	-8	hSpCas9	negative selection	2018947
52362459	52362482	12	-	26627737	HCT116	viability after 12 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.5792439374803727	[422]	[350,260,380]	5	hSpCas9	negative selection	2018948
52364089	52364112	12	+	26627737	HCT116	viability after 12 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.2886276791648895	[326]	[108,146,168]	-3	hSpCas9	negative selection	2018949
52364157	52364180	12	-	26627737	HCT116	viability after 12 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.18735864780087452	[423]	[284,194,276]	2	hSpCas9	negative selection	2018950
52365061	52365084	12	+	26627737	HCT116	viability after 12 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.028637204323390675	[764]	[373,350,506]	0	hSpCas9	negative selection	2018951
52367185	52367208	12	-	26627737	HCT116	viability after 12 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.41906405000175795	[434]	[276,367,275]	4	hSpCas9	negative selection	2018952
52360936	52360959	12	-	26627737	HCT116	viability after 15 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.32628156352717386	[533]	[200,241,284]	-3	hSpCas9	negative selection	2101262
52362459	52362482	12	-	26627737	HCT116	viability after 15 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.6390901251287774	[422]	[334,524,270]	6	hSpCas9	negative selection	2101263
52364089	52364112	12	+	26627737	HCT116	viability after 15 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.6161342844812533	[326]	[135,93,138]	-6	hSpCas9	negative selection	2101264
52364157	52364180	12	-	26627737	HCT116	viability after 15 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.15538088799257366	[423]	[328,252,238]	1	hSpCas9	negative selection	2101265
52365061	52365084	12	+	26627737	HCT116	viability after 15 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.26342357212086553	[764]	[476,388,246]	-3	hSpCas9	negative selection	2101266
52367185	52367208	12	-	26627737	HCT116	viability after 15 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.09036096869412769	[434]	[163,314,305]	0	hSpCas9	negative selection	2101267
52360936	52360959	12	-	26627737	HCT116	viability after 18 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.7542124059792901	[533]	[108,86,272]	-6	hSpCas9	negative selection	2183577
52362459	52362482	12	-	26627737	HCT116	viability after 18 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.4977521437593262	[422]	[365,207,297]	4	hSpCas9	negative selection	2183578
52364089	52364112	12	+	26627737	HCT116	viability after 18 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.8356741861049979	[326]	[69,93,101]	-6	hSpCas9	negative selection	2183579
52364157	52364180	12	-	26627737	HCT116	viability after 18 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.6930201978223194	[423]	[117,107,156]	-6	hSpCas9	negative selection	2183580
52365061	52365084	12	+	26627737	HCT116	viability after 18 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.018219882994372494	[764]	[336,283,514]	0	hSpCas9	negative selection	2183581
52367185	52367208	12	-	26627737	HCT116	viability after 18 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-0.02255416774821173	[434]	[152,195,275]	0	hSpCas9	negative selection	2183582
52367195	52367218	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.09003089988445286	[3,3]	[4,1]	-1	hSpCas9	positive selection	2998300
52367282	52367305	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAGCGCCGCCCCCTACCGAGGGG	KRT85	ENSG00000135443	0.38028086863742194	[3,2]	[2,4]	7	hSpCas9	positive selection	2998301
52367046	52367069	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTTCACGCACTGTGCGTTGGGG	KRT85	ENSG00000135443	-0.0297422718663628	[2,2]	[3,1]	0	hSpCas9	positive selection	2998302
52365112	52365135	12	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCTGGTAGAACTGCCACTTGG	KRT85	ENSG00000135443	0.10554912366720257	[3,4]	[4,3]	2	hSpCas9	positive selection	2998303
52367195	52367218	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.21110711399231455	[3,3]	[3,0]	-3	hSpCas9	positive selection	3066158
52367282	52367305	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAGCGCCGCCCCCTACCGAGGGG	KRT85	ENSG00000135443	-0.23721308745384578	[3,3]	[2,0]	-3	hSpCas9	positive selection	3066159
52367046	52367069	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTTCACGCACTGTGCGTTGGGG	KRT85	ENSG00000135443	0.059357165221060826	[2,2]	[2,1]	1	hSpCas9	positive selection	3066160
52365112	52365135	12	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCTGGTAGAACTGCCACTTGG	KRT85	ENSG00000135443	-0.1366601884225681	[3,3]	[4,0]	-2	hSpCas9	positive selection	3066161
52367385	52367408		-	24336571	A375	resistance to PLX after 7 days	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.041282951849283656	[46,51]	[49,50]	1	hSpCas9	positive selection	3123852
52365086	52365109		-	24336571	A375	resistance to PLX after 7 days	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.1454789155226025	[8,6]	[4,7]	-5	hSpCas9	positive selection	3123853
52365089	52365112		+	24336571	A375	resistance to PLX after 7 days	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.3610466806403231	[7,8]	[5,6]	-8	hSpCas9	positive selection	3123854
52367272	52367295		+	24336571	A375	resistance to PLX after 7 days	TAGCAGGACACCCCTCGGTAGGG	KRT85	ENSG00000135443	-0.2211335247153985	[6,5]	[5,4]	-6	hSpCas9	positive selection	3123855
52367385	52367408		-	24336571	A375	resistance to PLX after 14 days	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.029248882108290353	[44,56]	[23,23]	0	hSpCas9	positive selection	3181645
52365086	52365109		-	24336571	A375	resistance to PLX after 14 days	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.014738939599043377	[12,5]	[3,3]	0	hSpCas9	positive selection	3181646
52365089	52365112		+	24336571	A375	resistance to PLX after 14 days	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.18832328210436555	[8,6]	[2,2]	-2	hSpCas9	positive selection	3181647
52367272	52367295		+	24336571	A375	resistance to PLX after 14 days	TAGCAGGACACCCCTCGGTAGGG	KRT85	ENSG00000135443	-0.576647603498829	[10,6]	[1,1]	-6	hSpCas9	positive selection	3181648
52367385	52367408		-	24336571	A375	viability after 7 days	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.6302615874396256	[32]	[46,51]	8	hSpCas9	negative selection	3239438
52365086	52365109		-	24336571	A375	viability after 7 days	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.17677016093975062	[6]	[8,6]	2	hSpCas9	negative selection	3239439
52365089	52365112		+	24336571	A375	viability after 7 days	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.2405687994298914	[7]	[7,8]	3	hSpCas9	negative selection	3239440
52367272	52367295		+	24336571	A375	viability after 7 days	TAGCAGGACACCCCTCGGTAGGG	KRT85	ENSG00000135443	-0.11364540859452432	[7]	[6,5]	-2	hSpCas9	negative selection	3239441
52367385	52367408		-	24336571	A375	viability after 14 days	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.6964152466950297	[32]	[44,56]	8	hSpCas9	negative selection	3297231
52365086	52365109		-	24336571	A375	viability after 14 days	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.49251192030709234	[6]	[12,5]	6	hSpCas9	negative selection	3297232
52365089	52365112		+	24336571	A375	viability after 14 days	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.22095412798968828	[7]	[8,6]	3	hSpCas9	negative selection	3297233
52367272	52367295		+	24336571	A375	viability after 14 days	TAGCAGGACACCCCTCGGTAGGG	KRT85	ENSG00000135443	0.251336536272604	[7]	[10,6]	3	hSpCas9	negative selection	3297234
52364305	52364328	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.25046842875286124	[181,181]	[0,0]	-1	hSpCas9	positive selection	3376373
52364353	52364376	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	1.797894592808538	[43,43]	[0,0]	7	hSpCas9	positive selection	3376374
52367194	52367217	12	+	26780180	HT29	viability (Avana library 4 designs)	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	1.55319468160997	[]	[]	6	hSpCas9	negative selection	3435757
52367282	52367305	12	-	26780180	HT29	viability (Avana library 4 designs)	CAGCGCCGCCCCCTACCGAGGGG	KRT85	ENSG00000135443	0.406090891137125	[]	[]	1	hSpCas9	negative selection	3435758
52367045	52367068	12	+	26780180	HT29	viability (Avana library 4 designs)	GCTTCACGCACTGTGCGTTGGGG	KRT85	ENSG00000135443	1.26482134213851	[]	[]	5	hSpCas9	negative selection	3435759
52365111	52365134	12	+	26780180	HT29	viability (Avana library 4 designs)	GTTCTGGTAGAACTGCCACTTGG	KRT85	ENSG00000135443	-0.591704504654953	[]	[]	-8	hSpCas9	negative selection	3435760
52365111	52365134	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCTGGTAGAACTGCCACTTGG	KRT85	ENSG00000135443	4.61933544827574	[]	[]	7	hSpCas9	negative selection	3523479
52367194	52367217	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	3.53226585490801	[]	[]	5	hSpCas9	negative selection	3523480
52367282	52367305	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAGCGCCGCCCCCTACCGAGGGG	KRT85	ENSG00000135443	0.532566986707018	[]	[]	0	hSpCas9	negative selection	3523481
52367045	52367068	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTTCACGCACTGTGCGTTGGGG	KRT85	ENSG00000135443	-0.827385710756631	[]	[]	-1	hSpCas9	negative selection	3523482
52367370	52367393	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCATCCTGAGCTGATCCTGTAGG	KRT85	ENSG00000135443	-1.13114720380959	[]	[]	-1	hSpCas9	negative selection	3523483
52367267	52367290	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	6.07047094370573	[]	[]	9	hSpCas9	negative selection	3523484
52365111	52365134	12	+	26780180	A375	viability (Avana lentiGuide)	GTTCTGGTAGAACTGCCACTTGG	KRT85	ENSG00000135443	-4.96203397895536	[]	[]	-8	hSpCas9	negative selection	3632138
52367194	52367217	12	+	26780180	A375	viability (Avana lentiGuide)	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.385438045420399	[]	[]	0	hSpCas9	negative selection	3632139
52367282	52367305	12	-	26780180	A375	viability (Avana lentiGuide)	CAGCGCCGCCCCCTACCGAGGGG	KRT85	ENSG00000135443	-5.20506210198543	[]	[]	-8	hSpCas9	negative selection	3632140
52367045	52367068	12	+	26780180	A375	viability (Avana lentiGuide)	GCTTCACGCACTGTGCGTTGGGG	KRT85	ENSG00000135443	13.7480273209696	[]	[]	7	hSpCas9	negative selection	3632141
52367370	52367393	12	+	26780180	A375	viability (Avana lentiGuide)	GCATCCTGAGCTGATCCTGTAGG	KRT85	ENSG00000135443	0.0495332615990589	[]	[]	0	hSpCas9	negative selection	3632142
52367267	52367290	12	+	26780180	A375	viability (Avana lentiGuide)	CTCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	-1.44354343494756	[]	[]	-2	hSpCas9	negative selection	3632143
52365111	52365134	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCTGGTAGAACTGCCACTTGG	KRT85	ENSG00000135443	0.27875558413205187	[5]	[6,5]	7	hSpCas9	positive selection	3740797
52367194	52367217	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.22149203439507695	[4]	[5,4]	6	hSpCas9	positive selection	3740798
52367282	52367305	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAGCGCCGCCCCCTACCGAGGGG	KRT85	ENSG00000135443	-0.41843063679013187	[3]	[3,1]	-6	hSpCas9	positive selection	3740799
52367045	52367068	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTTCACGCACTGTGCGTTGGGG	KRT85	ENSG00000135443	-0.0037748027669352036	[4]	[5,3]	0	hSpCas9	positive selection	3740800
52367370	52367393	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCATCCTGAGCTGATCCTGTAGG	KRT85	ENSG00000135443	0.1775536701418059	[4]	[5,4]	5	hSpCas9	positive selection	3740801
52367267	52367290	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.2332996244712257	[4]	[5,5]	6	hSpCas9	positive selection	3740802
52365111	52365134	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCTGGTAGAACTGCCACTTGG	KRT85	ENSG00000135443	0.15694986824543092	[5]	[4,6]	3	hSpCas9	positive selection	3849404
52367194	52367217	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.49164140739372447	[5]	[3,2]	-6	hSpCas9	positive selection	3849405
52367282	52367305	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAGCGCCGCCCCCTACCGAGGGG	KRT85	ENSG00000135443	-0.2138643949473782	[4]	[2,3]	-3	hSpCas9	positive selection	3849406
52367045	52367068	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTTCACGCACTGTGCGTTGGGG	KRT85	ENSG00000135443	-0.07233851386814082	[5]	[4,4]	-1	hSpCas9	positive selection	3849407
52367370	52367393	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCATCCTGAGCTGATCCTGTAGG	KRT85	ENSG00000135443	0.18917784035187263	[5]	[5,5]	4	hSpCas9	positive selection	3849408
52367267	52367290	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.27808416598938845	[5]	[5,6]	7	hSpCas9	positive selection	3849409
52364353	52364376	12	-	26780180	A375	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.622116681439239	[]	[]	2	hSpCas9	negative selection	3955474
52367385	52367408	12	-	26780180	A375	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.937893570810319	[]	[]	4	hSpCas9	negative selection	3955475
52365086	52365109	12	-	26780180	A375	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	1.00309976799671	[]	[]	4	hSpCas9	negative selection	3955476
52365089	52365112	12	+	26780180	A375	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	1.00956895531944	[]	[]	5	hSpCas9	negative selection	3955477
52364305	52364328	12	-	26780180	A375	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	1.35164309360636	[]	[]	7	hSpCas9	negative selection	3955478
52367200	52367223	12	-	26780180	A375	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	1.30724523293734	[]	[]	7	hSpCas9	negative selection	3955479
52364353	52364376	12	-	26780180	HT29	viability (GeCKOv2 library)	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.600476277509493	[]	[]	2	hSpCas9	negative selection	4063440
52367385	52367408	12	-	26780180	HT29	viability (GeCKOv2 library)	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.610511660607968	[]	[]	2	hSpCas9	negative selection	4063441
52365086	52365109	12	-	26780180	HT29	viability (GeCKOv2 library)	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	1.25024405187913	[]	[]	6	hSpCas9	negative selection	4063442
52365089	52365112	12	+	26780180	HT29	viability (GeCKOv2 library)	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.891934289178807	[]	[]	4	hSpCas9	negative selection	4063443
52364305	52364328	12	-	26780180	HT29	viability (GeCKOv2 library)	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.770113501365099	[]	[]	3	hSpCas9	negative selection	4063444
52367200	52367223	12	-	26780180	HT29	viability (GeCKOv2 library)	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.925743733273335	[]	[]	4	hSpCas9	negative selection	4063445
52367385	52367408	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.2448348316172621	[5]	[3,4]	6	hSpCas9	positive selection	4147827
52365086	52365109	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.3918387004863784	[2]	[3,1]	8	hSpCas9	positive selection	4147828
52365089	52365112	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.4557402245481189	[2]	[0,1]	-8	hSpCas9	positive selection	4147829
52367272	52367295	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TAGCAGGACACCCCTCGGTAGGG	KRT85	ENSG00000135443	-0.47965093161039274	[3]	[1,0]	-8	hSpCas9	positive selection	4147830
52367385	52367408	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.7266725074455265	[5]	[2,1,5,3]	5	hSpCas9	positive selection	4211849
52365086	52365109	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.8588536015167619	[2]	[3,3,3,0]	5	hSpCas9	positive selection	4211850
52365089	52365112	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	1.2369667369333144	[1]	[4,0,1,0]	8	hSpCas9	positive selection	4211851
52367272	52367295	12	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TAGCAGGACACCCCTCGGTAGGG	KRT85	ENSG00000135443	0.7570434449684114	[2]	[1,1,4,0]	5	hSpCas9	positive selection	4211852
52367385	52367408	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.2560354032573743	[4]	[4,3]	5	hSpCas9	positive selection	4279245
52365086	52365109	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.13892966169006626	[1]	[1,0]	-3	hSpCas9	positive selection	4279246
52367200	52367223	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.002145587337896911	[3]	[3,1]	0	hSpCas9	positive selection	4279247
52365089	52365112	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.3370751712981249	[2]	[2,0]	-6	hSpCas9	positive selection	4343500
52364305	52364328	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.020815971624655295	[3]	[2,1]	0	hSpCas9	positive selection	4343501
52364353	52364376	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	-0.1248593075549459	[1]	[0,0]	-2	hSpCas9	positive selection	4343502
52364157	52364179	12	-	27760321	OCIAML3	viability	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.6492016137407957	[707,674]	[613,1155]	7	hSpCas9	negative selection	4413264
52365062	52365084	12	+	27760321	OCIAML3	viability	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.33639252936252473	[553,444]	[222,417]	-4	hSpCas9	negative selection	4413265
52367195	52367217	12	+	27760321	OCIAML3	viability	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.41866935405732586	[973,824]	[742,1189]	5	hSpCas9	negative selection	4413266
52367268	52367290	12	+	27760321	OCIAML3	viability	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.677239488860756	[539,471]	[498,803]	7	hSpCas9	negative selection	4413267
52367320	52367342	12	-	27760321	OCIAML3	viability	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.17175207756455352	[419,328]	[338,312]	2	hSpCas9	negative selection	4413268
52364157	52364179	12	-	27760321	OCIAML2	viability	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.3867859155949567	[707,674]	[636,857]	5	hSpCas9	negative selection	4496727
52365062	52365084	12	+	27760321	OCIAML2	viability	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.5053884675099569	[553,444]	[213,373]	-5	hSpCas9	negative selection	4496728
52367195	52367217	12	+	27760321	OCIAML2	viability	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.2233162336514697	[973,824]	[457,835]	-3	hSpCas9	negative selection	4496729
52367268	52367290	12	+	27760321	OCIAML2	viability	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.2006639837767826	[539,471]	[373,594]	2	hSpCas9	negative selection	4496730
52367320	52367342	12	-	27760321	OCIAML2	viability	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.4410030803830557	[419,328]	[414,399]	6	hSpCas9	negative selection	4496731
52364157	52364179	12	-	27760321	MV411	viability	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	1.0645335250579937	[707,674]	[784,1211]	7	hSpCas9	negative selection	4580190
52365062	52365084	12	+	27760321	MV411	viability	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.17989151573269088	[553,444]	[202,418]	-1	hSpCas9	negative selection	4580191
52367195	52367217	12	+	27760321	MV411	viability	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	1.1564669234531055	[973,824]	[1686,764]	8	hSpCas9	negative selection	4580192
52367268	52367290	12	+	27760321	MV411	viability	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.5058322364849841	[539,471]	[321,699]	3	hSpCas9	negative selection	4580193
52367320	52367342	12	-	27760321	MV411	viability	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	1.1635923829632753	[419,328]	[200,1073]	8	hSpCas9	negative selection	4580194
52364157	52364179	12	-	27760321	HL60	viability	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.09112461405469674	[707,674]	[618,584]	1	hSpCas9	negative selection	4663653
52365062	52365084	12	+	27760321	HL60	viability	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.32611604198605376	[553,444]	[327,318]	-4	hSpCas9	negative selection	4663654
52367195	52367217	12	+	27760321	HL60	viability	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.4920030860060991	[973,824]	[1054,1002]	6	hSpCas9	negative selection	4663655
52367268	52367290	12	+	27760321	HL60	viability	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	-0.45835869306764077	[539,471]	[172,434]	-5	hSpCas9	negative selection	4663656
52367320	52367342	12	-	27760321	HL60	viability	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.6451899236168597	[419,328]	[532,413]	7	hSpCas9	negative selection	4663657
52364157	52364179	12	-	27760321	HT1080	viability	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-1.0999909645295944	[674,526]	[20,210]	-4	hSpCas9	negative selection	4747116
52365062	52365084	12	+	27760321	HT1080	viability	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.7249007272526561	[444,346]	[30,165]	-3	hSpCas9	negative selection	4747117
52367195	52367217	12	+	27760321	HT1080	viability	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.37735512478104427	[824,643]	[286,481]	2	hSpCas9	negative selection	4747118
52367268	52367290	12	+	27760321	HT1080	viability	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	-1.1680814114609852	[471,368]	[22,130]	-4	hSpCas9	negative selection	4747119
52367320	52367342	12	-	27760321	HT1080	viability	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.49753524872605226	[328,256]	[149,180]	2	hSpCas9	negative selection	4747120
52364157	52364179	12	-	27760321	HT29	viability after 7 days	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.07487420320435867	[674,526]	[980,769,491]	-1	hSpCas9	negative selection	4830579
52365062	52365084	12	+	27760321	HT29	viability after 7 days	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.2062525400209754	[444,346]	[671,599,503]	3	hSpCas9	negative selection	4830580
52367195	52367217	12	+	27760321	HT29	viability after 7 days	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.588352508389268	[824,643]	[1344,1325,1570]	8	hSpCas9	negative selection	4830581
52367268	52367290	12	+	27760321	HT29	viability after 7 days	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.048474079551047544	[471,368]	[694,502,499]	0	hSpCas9	negative selection	4830582
52367320	52367342	12	-	27760321	HT29	viability after 7 days	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.5821874667846657	[328,256]	[418,669,580]	8	hSpCas9	negative selection	4830583
52364157	52364179	12	-	27760321	HT29	viability after 25 days	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.22072171659781104	[674,526]	[913,676,801]	2	hSpCas9	negative selection	4914042
52365062	52365084	12	+	27760321	HT29	viability after 25 days	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.09205869456173851	[444,346]	[495,315,650]	0	hSpCas9	negative selection	4914043
52367195	52367217	12	+	27760321	HT29	viability after 25 days	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.380848295120616	[824,643]	[972,1381,910]	4	hSpCas9	negative selection	4914044
52367268	52367290	12	+	27760321	HT29	viability after 25 days	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	-0.12415636232139811	[471,368]	[386,399,549]	-1	hSpCas9	negative selection	4914045
52367320	52367342	12	-	27760321	HT29	viability after 25 days	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	-0.143803999042749	[328,256]	[275,292,345]	-1	hSpCas9	negative selection	4914046
52364157	52364179	12	-	27760321	HT29	viability after 22 days	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.35463414296008977	[674,526]	[797,944,924]	4	hSpCas9	negative selection	4997505
52365062	52365084	12	+	27760321	HT29	viability after 22 days	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.0941751058851015	[444,346]	[469,552,442]	0	hSpCas9	negative selection	4997506
52367195	52367217	12	+	27760321	HT29	viability after 22 days	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.5677497939281342	[824,643]	[1700,986,1073]	6	hSpCas9	negative selection	4997507
52367268	52367290	12	+	27760321	HT29	viability after 22 days	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.02049456694019497	[471,368]	[460,653,363]	0	hSpCas9	negative selection	4997508
52367320	52367342	12	-	27760321	HT29	viability after 22 days	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.11920348636850372	[328,256]	[515,292,289]	1	hSpCas9	negative selection	4997509
52364157	52364179	12	-	27760321	HT29	viability after 19 days	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.25474229405737603	[674,526]	[627,946,862]	2	hSpCas9	negative selection	5080968
52365062	52365084	12	+	27760321	HT29	viability after 19 days	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.09793721899719895	[444,346]	[353,385,691]	0	hSpCas9	negative selection	5080969
52367195	52367217	12	+	27760321	HT29	viability after 19 days	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.5631153370279263	[824,643]	[1667,1334,781]	5	hSpCas9	negative selection	5080970
52367268	52367290	12	+	27760321	HT29	viability after 19 days	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.54986455261693	[471,368]	[394,591,1077]	5	hSpCas9	negative selection	5080971
52367320	52367342	12	-	27760321	HT29	viability after 19 days	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.07413557356912451	[328,256]	[330,429,296]	0	hSpCas9	negative selection	5080972
52364157	52364179	12	-	27760321	HT29	viability after 16 days	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.36273675575597075	[674,526]	[1186,604,838]	4	hSpCas9	negative selection	5164431
52365062	52365084	12	+	27760321	HT29	viability after 16 days	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.019231653798973014	[444,346]	[288,284,761]	0	hSpCas9	negative selection	5164432
52367195	52367217	12	+	27760321	HT29	viability after 16 days	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.33951833691275435	[824,643]	[1337,1056,751]	4	hSpCas9	negative selection	5164433
52367268	52367290	12	+	27760321	HT29	viability after 16 days	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.0836251311309743	[471,368]	[402,484,598]	0	hSpCas9	negative selection	5164434
52367320	52367342	12	-	27760321	HT29	viability after 16 days	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.17911105478102415	[328,256]	[265,389,446]	2	hSpCas9	negative selection	5164435
52364157	52364179	12	-	27760321	HT29	viability after 13 days	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.032766315252544476	[674,526]	[999,664,487]	0	hSpCas9	negative selection	5247894
52365062	52365084	12	+	27760321	HT29	viability after 13 days	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.5211779253945019	[444,346]	[518,884,578]	6	hSpCas9	negative selection	5247895
52367195	52367217	12	+	27760321	HT29	viability after 13 days	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.35642443076061414	[824,643]	[1204,954,1110]	4	hSpCas9	negative selection	5247896
52367268	52367290	12	+	27760321	HT29	viability after 13 days	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.4056731642081136	[471,368]	[657,587,689]	5	hSpCas9	negative selection	5247897
52367320	52367342	12	-	27760321	HT29	viability after 13 days	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	-0.20798336529590494	[328,256]	[302,339,242]	-2	hSpCas9	negative selection	5247898
52364157	52364179	12	-	27760321	HT29	viability after 10 days	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.04137854458311252	[674,526]	[769,841,707]	0	hSpCas9	negative selection	5331357
52365062	52365084	12	+	27760321	HT29	viability after 10 days	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.21534413635716607	[444,346]	[664,635,425]	3	hSpCas9	negative selection	5331358
52367195	52367217	12	+	27760321	HT29	viability after 10 days	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.5253229981185066	[824,643]	[1267,1232,1452]	7	hSpCas9	negative selection	5331359
52367268	52367290	12	+	27760321	HT29	viability after 10 days	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.20887606156192412	[471,368]	[631,444,735]	2	hSpCas9	negative selection	5331360
52367320	52367342	12	-	27760321	HT29	viability after 10 days	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	0.27160736427126153	[328,256]	[343,568,415]	3	hSpCas9	negative selection	5331361
52364157	52364179	12	-	27760321	MOLM13	viability	TTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.4129488852256984	[707,674]	[233,343]	-3	hSpCas9	negative selection	5414820
52365062	52365084	12	+	27760321	MOLM13	viability	CGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	1.1521641751473548	[553,444]	[376,831]	7	hSpCas9	negative selection	5414821
52367195	52367217	12	+	27760321	MOLM13	viability	AGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.13345375867472797	[973,824]	[618,499]	0	hSpCas9	negative selection	5414822
52367268	52367290	12	+	27760321	MOLM13	viability	TCGGTAGCAGGACACCCCTCGG	KRT85	ENSG00000135443	0.5399557666872945	[539,471]	[465,369]	4	hSpCas9	negative selection	5414823
52367320	52367342	12	-	27760321	MOLM13	viability	CAGCTGTGGCCCCCAAAACTGG	KRT85	ENSG00000135443	-0.24750132467418298	[419,328]	[340,36]	-2	hSpCas9	negative selection	5414824
52367370	52367393	12	+	27661255	K562	viability	GCATCCTGAGCTGATCCTGTAGG	KRT85	ENSG00000135443	0.130657886073818	[1285,1545]	[1352,1132]	4	dCas9-KRAB	negative selection	5489397
52367392	52367415	12	+	27661255	K562	viability	GAGCGGCACGACATCGTGTGAGG	KRT85	ENSG00000135443	0.17987813901300387	[600,940]	[764,629]	6	dCas9-KRAB	negative selection	5489398
52367445	52367468	12	+	27661255	K562	viability	GGTGCGGGCGGCAGAGTGCGAGG	KRT85	ENSG00000135443	0.06526723229915055	[813,968]	[779,710]	2	dCas9-KRAB	negative selection	5489399
52367197	52367220	12	-	27661255	K562	viability	GGGCCCCGGATAGCTGTAGGTGG	KRT85	ENSG00000135443	-0.059750310053183264	[1149,999]	[988,686]	-2	dCas9-KRAB	negative selection	5489400
52367385	52367408	12	-	27260156	BXPC3	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.06677955745451247	[1397]	[1080,1310,1451,1821]	-1	hSpCas9	negative selection	5551705
52365086	52365109	12	-	27260156	BXPC3	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.19053979844830016	[108]	[58,106,116,122]	-4	hSpCas9	negative selection	5551706
52367200	52367223	12	-	27260156	BXPC3	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.07319407882686003	[460]	[375,383,527,569]	-2	hSpCas9	negative selection	5551707
52365089	52365112	12	+	27260156	BXPC3	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.2579725880552942	[334]	[303,246,275,350]	-5	hSpCas9	negative selection	5615960
52364305	52364328	12	-	27260156	BXPC3	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.03882141067353287	[496]	[501,631,465,526]	0	hSpCas9	negative selection	5615961
52364353	52364376	12	-	27260156	BXPC3	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	1.1172170524757328	[71]	[148,132,163,215]	9	hSpCas9	negative selection	5615962
52367385	52367408	12	-	27260156	A673	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.08822307700862364	[1397]	[1615,1382,1697,1626]	-2	hSpCas9	negative selection	5672956
52365086	52365109	12	-	27260156	A673	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.2118814677636418	[108]	[171,135,131,169]	5	hSpCas9	negative selection	5672957
52367200	52367223	12	-	27260156	A673	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.09206163085642224	[460]	[490,589,449,541]	-2	hSpCas9	negative selection	5672958
52365089	52365112	12	+	27260156	A673	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.20082982252335801	[334]	[338,352,235,477]	-5	hSpCas9	negative selection	5737211
52364305	52364328	12	-	27260156	A673	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.1626888606490492	[496]	[494,645,447,535]	-4	hSpCas9	negative selection	5737212
52364353	52364376	12	-	27260156	A673	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.7094448527442667	[71]	[85,149,139,184]	9	hSpCas9	negative selection	5737213
52367385	52367408	12	-	27260156	A375	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.17074406346153803	[1397]	[1635,2046,1699,1972]	2	hSpCas9	negative selection	5794207
52365086	52365109	12	-	27260156	A375	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.1426146462593172	[108]	[133,147,53,127]	-2	hSpCas9	negative selection	5794208
52367200	52367223	12	-	27260156	A375	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.1279520045779952	[460]	[542,621,362,462]	-2	hSpCas9	negative selection	5794209
52365089	52365112	12	+	27260156	A375	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.1467890608727459	[334]	[335,395,303,378]	-2	hSpCas9	negative selection	5858462
52364305	52364328	12	-	27260156	A375	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.3611402022149798	[496]	[688,964,779,593]	5	hSpCas9	negative selection	5858463
52364353	52364376	12	-	27260156	A375	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.6865277306289044	[71]	[141,67,208,114]	8	hSpCas9	negative selection	5858464
52367385	52367408	12	-	27260156	COLO741	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.07604239352502784	[1397]	[1998,1937,1728]	1	hSpCas9	negative selection	5915458
52365086	52365109	12	-	27260156	COLO741	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.24967535759346648	[108]	[160,252,87]	5	hSpCas9	negative selection	5915459
52367200	52367223	12	-	27260156	COLO741	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.18211167173850687	[460]	[578,458,522]	-4	hSpCas9	negative selection	5915460
52365089	52365112	12	+	27260156	COLO741	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.20756324309156282	[334]	[494,290,337]	-4	hSpCas9	negative selection	5979713
52364305	52364328	12	-	27260156	COLO741	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.2151047484905868	[496]	[807,745,666]	4	hSpCas9	negative selection	5979714
52364353	52364376	12	-	27260156	COLO741	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.4871201401283334	[71]	[166,111,111]	8	hSpCas9	negative selection	5979715
52367385	52367408	12	-	27260156	CAL120	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.4484147079452472	[1397]	[3151,2070,2020]	6	hSpCas9	negative selection	6036709
52365086	52365109	12	-	27260156	CAL120	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.24926741052738421	[108]	[223,85,49]	-4	hSpCas9	negative selection	6036710
52367200	52367223	12	-	27260156	CAL120	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.11461940040513635	[460]	[572,502,519]	-2	hSpCas9	negative selection	6036711
52365089	52365112	12	+	27260156	CAL120	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.13909884015786833	[334]	[335,352,438]	-2	hSpCas9	negative selection	6100964
52364305	52364328	12	-	27260156	CAL120	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.2525570133839919	[496]	[816,773,632]	4	hSpCas9	negative selection	6100965
52364353	52364376	12	-	27260156	CAL120	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.22996485991275284	[71]	[151,106,63]	3	hSpCas9	negative selection	6100966
52367385	52367408	12	-	27260156	CADOES1	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.0749651226845347	[1397]	[1408,1529,1285,1248]	1	hSpCas9	negative selection	6157960
52365086	52365109	12	-	27260156	CADOES1	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.04385968022455344	[108]	[84,95,72,140]	0	hSpCas9	negative selection	6157961
52367200	52367223	12	-	27260156	CADOES1	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.16911767389060037	[460]	[394,283,389,458]	-3	hSpCas9	negative selection	6157962
52365089	52365112	12	+	27260156	CADOES1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.14385672178080933	[334]	[474,238,193,216]	-2	hSpCas9	negative selection	6222215
52364305	52364328	12	-	27260156	CADOES1	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.24811642029633207	[496]	[537,720,498,433]	4	hSpCas9	negative selection	6222216
52364353	52364376	12	-	27260156	CADOES1	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.4206056603491888	[71]	[138,69,68,79]	7	hSpCas9	negative selection	6222217
52367385	52367408	12	-	27260156	EWS502	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.06328372004858496	[1397]	[1454,1342,1704,1142]	-1	hSpCas9	negative selection	6279211
52365086	52365109	12	-	27260156	EWS502	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.226701514584166	[108]	[108,145,181,103]	4	hSpCas9	negative selection	6279212
52367200	52367223	12	-	27260156	EWS502	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.6430000463607146	[460]	[220,279,303,467]	-8	hSpCas9	negative selection	6279213
52365089	52365112	12	+	27260156	EWS502	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.08101427827861951	[334]	[329,338,415,425]	1	hSpCas9	negative selection	6343466
52364305	52364328	12	-	27260156	EWS502	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.07175733324719115	[496]	[491,428,563,522]	-1	hSpCas9	negative selection	6343467
52364353	52364376	12	-	27260156	EWS502	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.1617333505848948	[71]	[61,126,79,71]	3	hSpCas9	negative selection	6343468
52367385	52367408	12	-	27260156	EW8	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.07881833853520304	[1397]	[1244,1072,893,1124]	-1	hSpCas9	negative selection	6400462
52365086	52365109	12	-	27260156	EW8	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.3309063507561474	[108]	[138,96,81,133]	6	hSpCas9	negative selection	6400463
52367200	52367223	12	-	27260156	EW8	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.2875854623935714	[460]	[344,283,273,329]	-5	hSpCas9	negative selection	6400464
52365089	52365112	12	+	27260156	EW8	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.27729828135618206	[334]	[231,183,181,304]	-5	hSpCas9	negative selection	6464717
52364305	52364328	12	-	27260156	EW8	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.08521321965570557	[496]	[450,477,330,466]	1	hSpCas9	negative selection	6464718
52364353	52364376	12	-	27260156	EW8	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.32166107635678776	[71]	[7,97,86,88]	6	hSpCas9	negative selection	6464719
52367385	52367408	12	-	27260156	CORL105	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.21146378545094846	[1397]	[1879,1855,2280,1623]	4	hSpCas9	negative selection	6521713
52365086	52365109	12	-	27260156	CORL105	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.025005148536874078	[108]	[78,160,129,129]	0	hSpCas9	negative selection	6521714
52367200	52367223	12	-	27260156	CORL105	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.12796525375000656	[460]	[650,482,709,537]	2	hSpCas9	negative selection	6521715
52365089	52365112	12	+	27260156	CORL105	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.10147267547833205	[334]	[336,386,367,368]	-2	hSpCas9	negative selection	6585968
52364305	52364328	12	-	27260156	CORL105	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.09362265548990904	[496]	[661,346,579,604]	-2	hSpCas9	negative selection	6585969
52364353	52364376	12	-	27260156	CORL105	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.2489021684475783	[71]	[78,79,111,130]	4	hSpCas9	negative selection	6585970
52367385	52367408	12	-	27260156	HS294T	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.2111431689823049	[1397]	[674,689,491,638]	3	hSpCas9	negative selection	6642964
52365086	52365109	12	-	27260156	HS294T	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.13505410366878667	[108]	[19,69,48,47]	1	hSpCas9	negative selection	6642965
52367200	52367223	12	-	27260156	HS294T	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.22092226792115316	[460]	[82,183,186,164]	-3	hSpCas9	negative selection	6642966
52365089	52365112	12	+	27260156	HS294T	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.18916469955441462	[334]	[117,128,102,100]	-3	hSpCas9	negative selection	6707219
52364305	52364328	12	-	27260156	HS294T	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.566671617348305	[496]	[89,176,117,136]	-7	hSpCas9	negative selection	6707220
52364353	52364376	12	-	27260156	HS294T	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	1.812931205717033	[71]	[59,43,256,22]	9	hSpCas9	negative selection	6707221
52367385	52367408	12	-	27260156	HCC44	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.2523690544709041	[1397]	[1835,1621,2292,1870]	4	hSpCas9	negative selection	6764215
52365086	52365109	12	-	27260156	HCC44	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.051977934868229436	[108]	[19,169,76,181]	-1	hSpCas9	negative selection	6764216
52367200	52367223	12	-	27260156	HCC44	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.03721376997248123	[460]	[331,495,741,484]	0	hSpCas9	negative selection	6764217
52365089	52365112	12	+	27260156	HCC44	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.12927357940605477	[334]	[345,317,613,417]	2	hSpCas9	negative selection	6828470
52364305	52364328	12	-	27260156	HCC44	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.1833520055808286	[496]	[616,388,844,761]	3	hSpCas9	negative selection	6828471
52364353	52364376	12	-	27260156	HCC44	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.6091821170385017	[71]	[146,155,147,48]	8	hSpCas9	negative selection	6828472
52367385	52367408	12	-	27260156	G402	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.25238693776041843	[1397]	[2093,2190,1775,2074]	3	hSpCas9	negative selection	6885466
52365086	52365109	12	-	27260156	G402	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.06695769718791533	[108]	[192,149,143,80]	0	hSpCas9	negative selection	6885467
52367200	52367223	12	-	27260156	G402	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.1763574641074107	[460]	[358,612,296,696]	-2	hSpCas9	negative selection	6885468
52365089	52365112	12	+	27260156	G402	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.30114997364893104	[334]	[661,410,492,465]	4	hSpCas9	negative selection	6949721
52364305	52364328	12	-	27260156	G402	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.2767910436614394	[496]	[778,723,603,829]	3	hSpCas9	negative selection	6949722
52364353	52364376	12	-	27260156	G402	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.16864059570709644	[71]	[20,134,77,148]	2	hSpCas9	negative selection	6949723
52367385	52367408	12	-	27260156	L33	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.04786799648962137	[1397]	[1302,602,901,1572]	1	hSpCas9	negative selection	7006717
52365086	52365109	12	-	27260156	L33	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.23721579895920764	[108]	[157,28,135,68]	5	hSpCas9	negative selection	7006718
52367200	52367223	12	-	27260156	L33	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.017920856137955517	[460]	[397,201,301,496]	0	hSpCas9	negative selection	7006719
52365089	52365112	12	+	27260156	L33	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.2542347008429333	[334]	[224,99,217,308]	-5	hSpCas9	negative selection	7070972
52364305	52364328	12	-	27260156	L33	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.12680527164915031	[496]	[340,209,247,573]	-3	hSpCas9	negative selection	7070973
52364353	52364376	12	-	27260156	L33	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.5082249315215934	[71]	[79,49,67,99]	8	hSpCas9	negative selection	7070974
52367385	52367408	12	-	27260156	K562	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.3071026554040903	[1397]	[1911,1950,1326,1052]	4	hSpCas9	negative selection	7127968
52365086	52365109	12	-	27260156	K562	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.5863593423328906	[108]	[143,48,357,36]	7	hSpCas9	negative selection	7127969
52367200	52367223	12	-	27260156	K562	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.27294485126099555	[460]	[224,279,425,401]	-3	hSpCas9	negative selection	7127970
52365089	52365112	12	+	27260156	K562	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.17319805201986316	[334]	[283,134,276,342]	-2	hSpCas9	negative selection	7192223
52364305	52364328	12	-	27260156	K562	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.6596474563952363	[496]	[674,749,625,729]	8	hSpCas9	negative selection	7192224
52364353	52364376	12	-	27260156	K562	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.5938616228369136	[71]	[48,218,33,86]	7	hSpCas9	negative selection	7192225
52367385	52367408	12	-	27260156	HT29	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.1263362096614309	[1397]	[2098,1533,1985,1786]	2	hSpCas9	negative selection	7249219
52365086	52365109	12	-	27260156	HT29	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.217781822478595	[108]	[126,138,183,160]	4	hSpCas9	negative selection	7249220
52367200	52367223	12	-	27260156	HT29	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.15765031077945332	[460]	[455,446,622,474]	-3	hSpCas9	negative selection	7249221
52365089	52365112	12	+	27260156	HT29	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.14482960769558267	[334]	[304,542,554,397]	3	hSpCas9	negative selection	7313474
52364305	52364328	12	-	27260156	HT29	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.2794618013481463	[496]	[697,826,843,582]	5	hSpCas9	negative selection	7313475
52364353	52364376	12	-	27260156	HT29	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.6003059978448482	[71]	[146,196,82,111]	9	hSpCas9	negative selection	7313476
52367385	52367408	12	-	27260156	MHHES1	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.05203826017025159	[1397]	[1861,2025,1235,1104]	-1	hSpCas9	negative selection	7370470
52365086	52365109	12	-	27260156	MHHES1	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.3461576249549001	[108]	[96,275,165,99]	6	hSpCas9	negative selection	7370471
52367200	52367223	12	-	27260156	MHHES1	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.08427167088942725	[460]	[848,472,477,246]	-1	hSpCas9	negative selection	7370472
52365089	52365112	12	+	27260156	MHHES1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.5841624742639951	[334]	[240,238,350,183]	-8	hSpCas9	negative selection	7434725
52364305	52364328	12	-	27260156	MHHES1	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.021266863467708702	[496]	[594,718,564,377]	0	hSpCas9	negative selection	7434726
52364353	52364376	12	-	27260156	MHHES1	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.7426120826320428	[71]	[161,186,105,100]	9	hSpCas9	negative selection	7434727
52367385	52367408	12	-	27260156	MEWO	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.005948649525709948	[1397]	[1591,1242,1158]	0	hSpCas9	negative selection	7491721
52365086	52365109	12	-	27260156	MEWO	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.6243262052322234	[108]	[147,109,211]	9	hSpCas9	negative selection	7491722
52367200	52367223	12	-	27260156	MEWO	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.3321300482391053	[460]	[685,424,545]	7	hSpCas9	negative selection	7491723
52365089	52365112	12	+	27260156	MEWO	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.130499528808118	[334]	[374,294,205]	-3	hSpCas9	negative selection	7555976
52364305	52364328	12	-	27260156	MEWO	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.22981771341186302	[496]	[409,403,377]	-5	hSpCas9	negative selection	7555977
52364353	52364376	12	-	27260156	MEWO	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.9742648857313287	[71]	[178,137,88]	9	hSpCas9	negative selection	7555978
52367385	52367408	12	-	27260156	LNCAPCLONEFGC	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.10460017083831419	[1397]	[1330,1287,1327,1498]	1	hSpCas9	negative selection	7612972
52365086	52365109	12	-	27260156	LNCAPCLONEFGC	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.07630776969431885	[108]	[89,114,125,46]	-1	hSpCas9	negative selection	7612973
52367200	52367223	12	-	27260156	LNCAPCLONEFGC	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.7362373819939496	[460]	[286,184,255,278]	-8	hSpCas9	negative selection	7612974
52365089	52365112	12	+	27260156	LNCAPCLONEFGC	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.3534138751221398	[334]	[448,271,434,407]	5	hSpCas9	negative selection	7677227
52364305	52364328	12	-	27260156	LNCAPCLONEFGC	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.21883652170753853	[496]	[661,436,506,489]	3	hSpCas9	negative selection	7677228
52364353	52364376	12	-	27260156	LNCAPCLONEFGC	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.7423221933964252	[71]	[125,82,130,100]	9	hSpCas9	negative selection	7677229
52367385	52367408	12	-	27260156	PANC0327	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.04642294809277603	[1397]	[1472,898,1101,1719]	0	hSpCas9	negative selection	7734223
52365086	52365109	12	-	27260156	PANC0327	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.6067299427006141	[108]	[196,107,190,102]	8	hSpCas9	negative selection	7734224
52367200	52367223	12	-	27260156	PANC0327	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.6757774506079416	[460]	[258,136,313,330]	-7	hSpCas9	negative selection	7734225
52365089	52365112	12	+	27260156	PANC0327	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.5265724430863264	[334]	[214,160,284,171]	-6	hSpCas9	negative selection	7798478
52364305	52364328	12	-	27260156	PANC0327	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.21450657711009158	[496]	[406,409,269,432]	-3	hSpCas9	negative selection	7798479
52364353	52364376	12	-	27260156	PANC0327	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	1.72843763738814	[71]	[445,61,99,277]	9	hSpCas9	negative selection	7798480
52367385	52367408	12	-	27260156	NCIH2009	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.22966041661486547	[1397]	[3262,1694,2111]	3	hSpCas9	negative selection	7855474
52365086	52365109	12	-	27260156	NCIH2009	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.1758063923386599	[108]	[225,141,158]	2	hSpCas9	negative selection	7855475
52367200	52367223	12	-	27260156	NCIH2009	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.15278912738107342	[460]	[1025,615,567]	2	hSpCas9	negative selection	7855476
52365089	52365112	12	+	27260156	NCIH2009	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.07643158108048576	[334]	[518,541,282]	-1	hSpCas9	negative selection	7919729
52364305	52364328	12	-	27260156	NCIH2009	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.39014264941081184	[496]	[1100,922,741]	5	hSpCas9	negative selection	7919730
52364353	52364376	12	-	27260156	NCIH2009	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	-0.22768605446452517	[71]	[161,64,45]	-3	hSpCas9	negative selection	7919731
52367385	52367408	12	-	27260156	NCIH1373	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.22974491890480797	[1397]	[2258,1243,1657,615]	2	hSpCas9	negative selection	7976725
52365086	52365109	12	-	27260156	NCIH1373	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.8608556546574804	[108]	[136,56,589,23]	8	hSpCas9	negative selection	7976726
52367200	52367223	12	-	27260156	NCIH1373	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-1.1339063165037022	[460]	[158,123,354,79]	-8	hSpCas9	negative selection	7976727
52365089	52365112	12	+	27260156	NCIH1373	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.40406432062970876	[334]	[368,191,316,72]	-4	hSpCas9	negative selection	8040980
52364305	52364328	12	-	27260156	NCIH1373	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.23947129516809745	[496]	[516,615,257,128]	-2	hSpCas9	negative selection	8040981
52364353	52364376	12	-	27260156	NCIH1373	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	-0.4067262129184419	[71]	[13,79,18,32]	-4	hSpCas9	negative selection	8040982
52367385	52367408	12	-	27260156	PATU8902	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.36547159057012424	[1397]	[1892,3379,2057,2850]	4	hSpCas9	negative selection	8097976
52365086	52365109	12	-	27260156	PATU8902	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.33656110829941266	[108]	[9,184,200,56]	-3	hSpCas9	negative selection	8097977
52367200	52367223	12	-	27260156	PATU8902	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.781230876082169	[460]	[314,523,189,529]	-6	hSpCas9	negative selection	8097978
52365089	52365112	12	+	27260156	PATU8902	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.1286397048643027	[334]	[532,424,612,427]	1	hSpCas9	negative selection	8162231
52364305	52364328	12	-	27260156	PATU8902	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.07723397223874161	[496]	[749,618,486,825]	0	hSpCas9	negative selection	8162232
52364353	52364376	12	-	27260156	PATU8902	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.613535540026144	[71]	[21,87,189,324]	6	hSpCas9	negative selection	8162233
52367385	52367408	12	-	27260156	PANC1	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.223600817159735	[1397]	[1430,1166,1432,1489]	3	hSpCas9	negative selection	8219227
52365086	52365109	12	-	27260156	PANC1	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.20670153875215913	[108]	[70,89,61,98]	-3	hSpCas9	negative selection	8219228
52367200	52367223	12	-	27260156	PANC1	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.21695701986012852	[460]	[423,364,610,421]	3	hSpCas9	negative selection	8219229
52365089	52365112	12	+	27260156	PANC1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.19303761725773838	[334]	[589,252,233,227]	3	hSpCas9	negative selection	8283482
52364305	52364328	12	-	27260156	PANC1	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.39968507945906073	[496]	[795,606,505,369]	6	hSpCas9	negative selection	8283483
52364353	52364376	12	-	27260156	PANC1	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.9683464794723924	[71]	[72,165,96,150]	9	hSpCas9	negative selection	8283484
52367385	52367408	12	-	27260156	PANC0813	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.20115692947982944	[1397]	[2013,1857,2099,1604]	3	hSpCas9	negative selection	8340478
52365086	52365109	12	-	27260156	PANC0813	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.7729251765775527	[108]	[327,131,122,296]	9	hSpCas9	negative selection	8340479
52367200	52367223	12	-	27260156	PANC0813	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.1916480573743373	[460]	[525,250,605,515]	-3	hSpCas9	negative selection	8340480
52365089	52365112	12	+	27260156	PANC0813	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.2314527740813631	[334]	[524,331,303,203]	-4	hSpCas9	negative selection	8404733
52364305	52364328	12	-	27260156	PANC0813	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.31362915050992063	[496]	[539,562,502,288]	-5	hSpCas9	negative selection	8404734
52364353	52364376	12	-	27260156	PANC0813	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.29604491433772084	[71]	[96,178,82,57]	5	hSpCas9	negative selection	8404735
52367385	52367408	12	-	27260156	RDES	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.14529021235942463	[1397]	[1091,1440,1665,1697]	-2	hSpCas9	negative selection	8461729
52365086	52365109	12	-	27260156	RDES	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.5161582963047779	[108]	[94,123,32,87]	-7	hSpCas9	negative selection	8461730
52367200	52367223	12	-	27260156	RDES	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.416899635935585	[460]	[283,328,455,567]	-6	hSpCas9	negative selection	8461731
52365089	52365112	12	+	27260156	RDES	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.017289294391381493	[334]	[238,387,477,451]	0	hSpCas9	negative selection	8525984
52364305	52364328	12	-	27260156	RDES	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.30096863002819624	[496]	[537,647,677,1020]	5	hSpCas9	negative selection	8525985
52364353	52364376	12	-	27260156	RDES	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.11684683967218579	[71]	[74,92,91,100]	2	hSpCas9	negative selection	8525986
52367385	52367408	12	-	27260156	PC3	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.027929671954493474	[1397]	[879,1391,2134,1665]	0	hSpCas9	negative selection	8582980
52365086	52365109	12	-	27260156	PC3	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.1600622531062279	[108]	[75,71,178,92]	-4	hSpCas9	negative selection	8582981
52367200	52367223	12	-	27260156	PC3	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.21762702641541712	[460]	[212,468,1173,645]	5	hSpCas9	negative selection	8582982
52365089	52365112	12	+	27260156	PC3	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.10688496402863834	[334]	[148,346,645,271]	-2	hSpCas9	negative selection	8647235
52364305	52364328	12	-	27260156	PC3	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.009707932853965817	[496]	[260,595,714,537]	0	hSpCas9	negative selection	8647236
52364353	52364376	12	-	27260156	PC3	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.5677876113096256	[71]	[59,95,251,84]	9	hSpCas9	negative selection	8647237
52367385	52367408	12	-	27260156	PATU8988T	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.10925716569868693	[1397]	[964,1581,1672,1630]	2	hSpCas9	negative selection	8704231
52365086	52365109	12	-	27260156	PATU8988T	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.18678290833898314	[108]	[61,90,218,101]	3	hSpCas9	negative selection	8704232
52367200	52367223	12	-	27260156	PATU8988T	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.10584110198676461	[460]	[319,497,650,444]	1	hSpCas9	negative selection	8704233
52365089	52365112	12	+	27260156	PATU8988T	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.09044422601979896	[334]	[454,208,201,345]	-1	hSpCas9	negative selection	8768486
52364305	52364328	12	-	27260156	PATU8988T	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.14932508845320414	[496]	[336,598,516,696]	2	hSpCas9	negative selection	8768487
52364353	52364376	12	-	27260156	PATU8988T	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.5177621105446439	[71]	[66,186,55,96]	8	hSpCas9	negative selection	8768488
52367385	52367408	12	-	27260156	T47D	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.08314414551295046	[1397]	[1628,1226,1715,1603]	-2	hSpCas9	negative selection	8825482
52365086	52365109	12	-	27260156	T47D	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.312758749255563	[108]	[96,78,140,92]	-6	hSpCas9	negative selection	8825483
52367200	52367223	12	-	27260156	T47D	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.30783169103988195	[460]	[454,406,433,441]	-6	hSpCas9	negative selection	8825484
52365089	52365112	12	+	27260156	T47D	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.10812626422634464	[334]	[340,400,362,338]	-2	hSpCas9	negative selection	8889737
52364305	52364328	12	-	27260156	T47D	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.18432853874393174	[496]	[632,636,549,819]	4	hSpCas9	negative selection	8889738
52364353	52364376	12	-	27260156	T47D	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.21476444269936357	[71]	[112,82,69,125]	4	hSpCas9	negative selection	8889739
52367385	52367408	12	-	27260156	SU8686	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.20539216264272042	[1397]	[1487,1406,1636,1942]	3	hSpCas9	negative selection	8946733
52365086	52365109	12	-	27260156	SU8686	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	0.34657549312693914	[108]	[84,149,95,236]	6	hSpCas9	negative selection	8946734
52367200	52367223	12	-	27260156	SU8686	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.22503906548704747	[460]	[307,336,440,512]	-4	hSpCas9	negative selection	8946735
52365089	52365112	12	+	27260156	SU8686	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.21751599423792278	[334]	[161,315,442,223]	-4	hSpCas9	negative selection	9010988
52364305	52364328	12	-	27260156	SU8686	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.1494650168141538	[496]	[464,460,364,481]	-3	hSpCas9	negative selection	9010989
52364353	52364376	12	-	27260156	SU8686	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.37348327570980855	[71]	[68,68,154,81]	6	hSpCas9	negative selection	9010990
52367385	52367408	12	-	27260156	SKES1	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.14352616028667842	[1397]	[1823,1652,1279,1454]	3	hSpCas9	negative selection	9067984
52365086	52365109	12	-	27260156	SKES1	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.20619066421832555	[108]	[119,60,63,126]	-4	hSpCas9	negative selection	9067985
52367200	52367223	12	-	27260156	SKES1	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.05841760078879743	[460]	[569,429,404,380]	-1	hSpCas9	negative selection	9067986
52365089	52365112	12	+	27260156	SKES1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.05664589538833831	[334]	[342,296,347,386]	1	hSpCas9	negative selection	9132239
52364305	52364328	12	-	27260156	SKES1	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.008513900118126055	[496]	[488,551,465,468]	0	hSpCas9	negative selection	9132240
52364353	52364376	12	-	27260156	SKES1	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.350099480223236	[71]	[145,54,69,96]	7	hSpCas9	negative selection	9132241
52367385	52367408	12	-	27260156	TOV112D	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.07027206892561533	[1397]	[1447,1622,1496,1348]	1	hSpCas9	negative selection	9189235
52365086	52365109	12	-	27260156	TOV112D	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.6842414379167461	[108]	[34,116,62,65]	-8	hSpCas9	negative selection	9189236
52367200	52367223	12	-	27260156	TOV112D	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.1268916727943641	[460]	[479,569,378,305]	-2	hSpCas9	negative selection	9189237
52365089	52365112	12	+	27260156	TOV112D	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.09059108780174402	[334]	[382,527,325,238]	1	hSpCas9	negative selection	9253490
52364305	52364328	12	-	27260156	TOV112D	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.23817835062604048	[496]	[514,736,454,668]	4	hSpCas9	negative selection	9253491
52364353	52364376	12	-	27260156	TOV112D	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.7327142251010885	[71]	[121,160,142,64]	9	hSpCas9	negative selection	9253492
52367385	52367408	12	-	27260156	TC71	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	-0.09082904117140345	[1397]	[1452,1546,1139,1501]	-2	hSpCas9	negative selection	9310486
52365086	52365109	12	-	27260156	TC71	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.08539670173502234	[108]	[150,101,83,102]	-2	hSpCas9	negative selection	9310487
52367200	52367223	12	-	27260156	TC71	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	-0.01368177692590225	[460]	[475,513,494,471]	0	hSpCas9	negative selection	9310488
52365089	52365112	12	+	27260156	TC71	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.2623738903649442	[334]	[354,358,255,222]	-6	hSpCas9	negative selection	9374741
52364305	52364328	12	-	27260156	TC71	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	0.04400947638835176	[496]	[562,573,460,604]	1	hSpCas9	negative selection	9374742
52364353	52364376	12	-	27260156	TC71	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	0.5750825834698583	[71]	[137,89,89,143]	9	hSpCas9	negative selection	9374743
52367385	52367408	12	-	27260156	TC32	viability	CGATGTCGTGCCGCTCCTACAGG	KRT85	ENSG00000135443	0.15073436225985737	[1397]	[1223,1220,1939,1569]	2	hSpCas9	negative selection	9431737
52365086	52365109	12	-	27260156	TC32	viability	GCGCTGCTGCGAGAGCAACCTGG	KRT85	ENSG00000135443	-0.06341001073747865	[108]	[75,35,161,153]	-1	hSpCas9	negative selection	9431738
52367200	52367223	12	-	27260156	TC32	viability	TGCGGGCCCCGGATAGCTGTAGG	KRT85	ENSG00000135443	0.02205168053798897	[460]	[394,359,586,452]	0	hSpCas9	negative selection	9431739
52365089	52365112	12	+	27260156	TC32	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.25729009547589354	[334]	[324,112,436,241]	-5	hSpCas9	negative selection	9495992
52364305	52364328	12	-	27260156	TC32	viability	TGAGTTTGTCGTTCTAAAGAAGG	KRT85	ENSG00000135443	-0.09462616202208379	[496]	[412,337,516,513]	-2	hSpCas9	negative selection	9495993
52364353	52364376	12	-	27260156	TC32	viability	CACACCCAGGTATGAAGAGGAGG	KRT85	ENSG00000135443	-0.061018455000215965	[71]	[37,11,134,109]	-1	hSpCas9	negative selection	9495994
52360936	52360959	12	-	27869803	HPAFII	viability after 27 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	1.2843411210551876	[185]	[103,349,NaN]	9	hSpCas9	negative selection	9547222
52362459	52362482	12	-	27869803	HPAFII	viability after 27 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.23939467274032067	[392]	[226,257,NaN]	2	hSpCas9	negative selection	9547223
52364089	52364112	12	+	27869803	HPAFII	viability after 27 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.15589072653719607	[282]	[66,188,NaN]	-1	hSpCas9	negative selection	9547224
52364157	52364180	12	-	27869803	HPAFII	viability after 27 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.664527653032978	[275]	[120,66,NaN]	-5	hSpCas9	negative selection	9547225
52365061	52365084	12	+	27869803	HPAFII	viability after 27 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.41937643500318145	[776]	[179,409,NaN]	-3	hSpCas9	negative selection	9547226
52367185	52367208	12	-	27869803	HPAFII	viability after 27 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-0.8932199987468521	[342]	[149,52,NaN]	-6	hSpCas9	negative selection	9547227
52360936	52360959	12	-	27869803	HPAFII	viability after 15 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.34577234858505923	[185]	[311,217,NaN]	4	hSpCas9	negative selection	9629671
52362459	52362482	12	-	27869803	HPAFII	viability after 15 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.5789263391269794	[392]	[715,577,NaN]	6	hSpCas9	negative selection	9629672
52364089	52364112	12	+	27869803	HPAFII	viability after 15 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.4920004562666763	[282]	[629,301,NaN]	5	hSpCas9	negative selection	9629673
52364157	52364180	12	-	27869803	HPAFII	viability after 15 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.3564197101770291	[275]	[346,159,NaN]	-4	hSpCas9	negative selection	9629674
52365061	52365084	12	+	27869803	HPAFII	viability after 15 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.7067859292117156	[776]	[658,419,NaN]	-6	hSpCas9	negative selection	9629675
52367185	52367208	12	-	27869803	HPAFII	viability after 15 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-0.462339081988137	[342]	[335,224,NaN]	-5	hSpCas9	negative selection	9629676
52360936	52360959	12	-	27869803	ASPC1	viability after 36 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	0.02103899879193083	[532]	[238,186,152]	0	hSpCas9	negative selection	9712120
52362459	52362482	12	-	27869803	ASPC1	viability after 36 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.7131119593124879	[872]	[501,551,450]	7	hSpCas9	negative selection	9712121
52364089	52364112	12	+	27869803	ASPC1	viability after 36 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.041924293967537274	[1001]	[738,206,211]	0	hSpCas9	negative selection	9712122
52364157	52364180	12	-	27869803	ASPC1	viability after 36 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.07250618310755214	[765]	[516,295,100]	0	hSpCas9	negative selection	9712123
52365061	52365084	12	+	27869803	ASPC1	viability after 36 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.14844125018284116	[1582]	[765,346,425]	-1	hSpCas9	negative selection	9712124
52367185	52367208	12	-	27869803	ASPC1	viability after 36 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	0.43385084054457734	[844]	[181,841,193]	4	hSpCas9	negative selection	9712125
52360936	52360959	12	-	27869803	PATU8988S	viability after 35 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.32040484505934297	[424]	[171,101,NaN]	-3	hSpCas9	negative selection	9794569
52362459	52362482	12	-	27869803	PATU8988S	viability after 35 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.1755091341540509	[795]	[388,334,NaN]	2	hSpCas9	negative selection	9794570
52364089	52364112	12	+	27869803	PATU8988S	viability after 35 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.34704751430868613	[696]	[382,330,NaN]	4	hSpCas9	negative selection	9794571
52364157	52364180	12	-	27869803	PATU8988S	viability after 35 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.08429903858359244	[483]	[276,135,NaN]	1	hSpCas9	negative selection	9794572
52365061	52365084	12	+	27869803	PATU8988S	viability after 35 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.18170761109914202	[1217]	[509,602,NaN]	2	hSpCas9	negative selection	9794573
52367185	52367208	12	-	27869803	PATU8988S	viability after 35 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-0.3126918787355555	[809]	[331,192,NaN]	-3	hSpCas9	negative selection	9794574
52360936	52360959	12	-	27869803	PATU8988S	viability after 31 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	-0.37182845579987656	[424]	[148,107,NaN]	-4	hSpCas9	negative selection	9877018
52362459	52362482	12	-	27869803	PATU8988S	viability after 31 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.07394838866853726	[795]	[396,253,NaN]	0	hSpCas9	negative selection	9877019
52364089	52364112	12	+	27869803	PATU8988S	viability after 31 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.16509195574456942	[696]	[209,440,NaN]	2	hSpCas9	negative selection	9877020
52364157	52364180	12	-	27869803	PATU8988S	viability after 31 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	0.4013799665555209	[483]	[341,143,NaN]	5	hSpCas9	negative selection	9877021
52365061	52365084	12	+	27869803	PATU8988S	viability after 31 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.22580069769853006	[1217]	[347,847,NaN]	3	hSpCas9	negative selection	9877022
52367185	52367208	12	-	27869803	PATU8988S	viability after 31 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-0.025476262058954813	[809]	[359,262,NaN]	0	hSpCas9	negative selection	9877023
52360936	52360959	12	-	27869803	HPAFII	viability after 35 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	2.287452548117876	[185]	[73,893,NaN]	9	hSpCas9	negative selection	9959467
52362459	52362482	12	-	27869803	HPAFII	viability after 35 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.25689064998455624	[392]	[169,313,NaN]	1	hSpCas9	negative selection	9959468
52364089	52364112	12	+	27869803	HPAFII	viability after 35 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.9230470922497591	[282]	[162,393,NaN]	6	hSpCas9	negative selection	9959469
52364157	52364180	12	-	27869803	HPAFII	viability after 35 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.9939793551925118	[275]	[24,120,NaN]	-5	hSpCas9	negative selection	9959470
52365061	52365084	12	+	27869803	HPAFII	viability after 35 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.35502639225434396	[776]	[101,538,NaN]	-2	hSpCas9	negative selection	9959471
52367185	52367208	12	-	27869803	HPAFII	viability after 35 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-0.7216091717089715	[342]	[117,90,NaN]	-4	hSpCas9	negative selection	9959472
52360936	52360959	12	-	27869803	HPAFII	viability after 31 days	CATAGGCGGCAGCATCACGGTGG	KRT85	ENSG00000135443	1.5277293543826733	[185]	[65,556,NaN]	9	hSpCas9	negative selection	10041916
52362459	52362482	12	-	27869803	HPAFII	viability after 31 days	CACCTGATAGCGTGCCAAGCTGG	KRT85	ENSG00000135443	0.31256639745409576	[392]	[137,421,NaN]	2	hSpCas9	negative selection	10041917
52364089	52364112	12	+	27869803	HPAFII	viability after 31 days	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.5148982278582307	[282]	[113,349,NaN]	4	hSpCas9	negative selection	10041918
52364157	52364180	12	-	27869803	HPAFII	viability after 31 days	TTTGTCCCACGGCCAGGACGTGG	KRT85	ENSG00000135443	-0.5730300562094359	[275]	[50,161,NaN]	-4	hSpCas9	negative selection	10041919
52365061	52365084	12	+	27869803	HPAFII	viability after 31 days	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.2688383972675146	[776]	[203,533,NaN]	-2	hSpCas9	negative selection	10041920
52367185	52367208	12	-	27869803	HPAFII	viability after 31 days	GCTGTAGGTGGCTTCCGAGCCGG	KRT85	ENSG00000135443	-1.565374839423322	[342]	[65,63,NaN]	-7	hSpCas9	negative selection	10041921
52367265	52367288	12	-	28162770	P31FUJ	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-0.1173249869944426	[71]	[77]	-1	hSpCas9	negative selection	10181732
52364067	52364090	12	-	28162770	P31FUJ	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.17372379500894783	[254]	[337]	1	hSpCas9	negative selection	10181733
52365089	52365112	12	+	28162770	P31FUJ	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.7075738128992028	[246]	[473]	7	hSpCas9	negative selection	10181734
52364124	52364147	12	-	28162770	P31FUJ	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	0.5770949122056788	[161]	[283]	6	hSpCas9	negative selection	10181735
52362324	52362347	12	-	28162770	P31FUJ	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-3.434436065584029	[183]	[19]	-9	hSpCas9	negative selection	10181736
52367194	52367217	12	+	28162770	P31FUJ	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.274501495694767	[350]	[340]	-3	hSpCas9	negative selection	10181737
52365061	52365084	12	+	28162770	P31FUJ	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.05600661589111944	[563]	[688]	0	hSpCas9	negative selection	10181738
52364318	52364341	12	+	28162770	P31FUJ	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	-0.13421163082578502	[508]	[544]	-1	hSpCas9	negative selection	10181739
52364103	52364126	12	-	28162770	P31FUJ	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	0.2016006197313963	[221]	[299]	2	hSpCas9	negative selection	10181740
52364089	52364112	12	+	28162770	P31FUJ	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.4015855133196202	[372]	[578]	4	hSpCas9	negative selection	10181741
52367265	52367288	12	-	28162770	TF1	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	NaN	[NaN]	[35]	1	hSpCas9	negative selection	10351098
52364067	52364090	12	-	28162770	TF1	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	NaN	[NaN]	[117]	1	hSpCas9	negative selection	10351099
52365089	52365112	12	+	28162770	TF1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	NaN	[NaN]	[211]	1	hSpCas9	negative selection	10351100
52364124	52364147	12	-	28162770	TF1	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	NaN	[NaN]	[116]	1	hSpCas9	negative selection	10351101
52362324	52362347	12	-	28162770	TF1	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	NaN	[NaN]	[46]	1	hSpCas9	negative selection	10351102
52367194	52367217	12	+	28162770	TF1	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	NaN	[NaN]	[359]	1	hSpCas9	negative selection	10351103
52365061	52365084	12	+	28162770	TF1	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	NaN	[NaN]	[363]	1	hSpCas9	negative selection	10351104
52364318	52364341	12	+	28162770	TF1	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	NaN	[NaN]	[517]	1	hSpCas9	negative selection	10351105
52364103	52364126	12	-	28162770	TF1	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	NaN	[NaN]	[392]	1	hSpCas9	negative selection	10351106
52364089	52364112	12	+	28162770	TF1	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10351107
52367265	52367288	12	-	28162770	SKM1	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	1.4106590587682695	[19]	[93]	9	hSpCas9	negative selection	10520464
52364067	52364090	12	-	28162770	SKM1	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	-0.43343641010435263	[54]	[71]	-4	hSpCas9	negative selection	10520465
52365089	52365112	12	+	28162770	SKM1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.3706433799203904	[62]	[143]	3	hSpCas9	negative selection	10520466
52364124	52364147	12	-	28162770	SKM1	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.4223942393127676	[46]	[61]	-3	hSpCas9	negative selection	10520467
52362324	52362347	12	-	28162770	SKM1	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-3.0183989108255087	[54]	[11]	-9	hSpCas9	negative selection	10520468
52367194	52367217	12	+	28162770	SKM1	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.028452575489431586	[119]	[207]	0	hSpCas9	negative selection	10520469
52365061	52365084	12	+	28162770	SKM1	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.1858851093507463	[156]	[243]	-1	hSpCas9	negative selection	10520470
52364318	52364341	12	+	28162770	SKM1	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.47078005120584043	[119]	[293]	4	hSpCas9	negative selection	10520471
52364103	52364126	12	-	28162770	SKM1	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.12317123274257058	[68]	[111]	-1	hSpCas9	negative selection	10520472
52364089	52364112	12	+	28162770	SKM1	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.11262229312597039	[78]	[150]	1	hSpCas9	negative selection	10520473
52367265	52367288	12	-	28162770	SKM1	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	1.4106590587682695	[19]	[93]	9	hSpCas9	negative selection	10689830
52364067	52364090	12	-	28162770	SKM1	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	-0.43343641010435263	[54]	[71]	-4	hSpCas9	negative selection	10689831
52365089	52365112	12	+	28162770	SKM1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.3706433799203904	[62]	[143]	3	hSpCas9	negative selection	10689832
52364124	52364147	12	-	28162770	SKM1	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.4223942393127676	[46]	[61]	-3	hSpCas9	negative selection	10689833
52362324	52362347	12	-	28162770	SKM1	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-3.0183989108255087	[54]	[11]	-9	hSpCas9	negative selection	10689834
52367194	52367217	12	+	28162770	SKM1	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.028452575489431586	[119]	[207]	0	hSpCas9	negative selection	10689835
52365061	52365084	12	+	28162770	SKM1	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.1858851093507463	[156]	[243]	-1	hSpCas9	negative selection	10689836
52364318	52364341	12	+	28162770	SKM1	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.47078005120584043	[119]	[293]	4	hSpCas9	negative selection	10689837
52364103	52364126	12	-	28162770	SKM1	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.12317123274257058	[68]	[111]	-1	hSpCas9	negative selection	10689838
52364089	52364112	12	+	28162770	SKM1	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.11262229312597039	[78]	[150]	1	hSpCas9	negative selection	10689839
52367265	52367288	12	-	28162770	PL21	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-1.302360726039863	[67]	[11]	-7	hSpCas9	negative selection	10859196
52364067	52364090	12	-	28162770	PL21	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	-1.3253218744831743	[189]	[32]	-7	hSpCas9	negative selection	10859197
52365089	52365112	12	+	28162770	PL21	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.33865947857074796	[257]	[141]	3	hSpCas9	negative selection	10859198
52364124	52364147	12	-	28162770	PL21	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	0.27754411817492686	[126]	[66]	2	hSpCas9	negative selection	10859199
52362324	52362347	12	-	28162770	PL21	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-0.9580082191766388	[182]	[40]	-6	hSpCas9	negative selection	10859200
52367194	52367217	12	+	28162770	PL21	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.8080632636537874	[373]	[284]	7	hSpCas9	negative selection	10859201
52365061	52365084	12	+	28162770	PL21	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.0226809403616004	[431]	[190]	0	hSpCas9	negative selection	10859202
52364318	52364341	12	+	28162770	PL21	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	-0.5259376635341501	[439]	[132]	-4	hSpCas9	negative selection	10859203
52364103	52364126	12	-	28162770	PL21	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.24043297689666132	[170]	[62]	-2	hSpCas9	negative selection	10859204
52364089	52364112	12	+	28162770	PL21	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.13196811184774093	[324]	[154]	1	hSpCas9	negative selection	10859205
52367265	52367288	12	-	28162770	P31FUJ	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-0.1173249869944426	[71]	[77]	-1	hSpCas9	negative selection	11028562
52364067	52364090	12	-	28162770	P31FUJ	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.17372379500894783	[254]	[337]	1	hSpCas9	negative selection	11028563
52365089	52365112	12	+	28162770	P31FUJ	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.7075738128992028	[246]	[473]	7	hSpCas9	negative selection	11028564
52364124	52364147	12	-	28162770	P31FUJ	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	0.5770949122056788	[161]	[283]	6	hSpCas9	negative selection	11028565
52362324	52362347	12	-	28162770	P31FUJ	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-3.434436065584029	[183]	[19]	-9	hSpCas9	negative selection	11028566
52367194	52367217	12	+	28162770	P31FUJ	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.274501495694767	[350]	[340]	-3	hSpCas9	negative selection	11028567
52365061	52365084	12	+	28162770	P31FUJ	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.05600661589111944	[563]	[688]	0	hSpCas9	negative selection	11028568
52364318	52364341	12	+	28162770	P31FUJ	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	-0.13421163082578502	[508]	[544]	-1	hSpCas9	negative selection	11028569
52364103	52364126	12	-	28162770	P31FUJ	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	0.2016006197313963	[221]	[299]	2	hSpCas9	negative selection	11028570
52364089	52364112	12	+	28162770	P31FUJ	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.4015855133196202	[372]	[578]	4	hSpCas9	negative selection	11028571
52367265	52367288	12	-	28162770	OCIAML5	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-0.38739830386055263	[49]	[68]	-3	hSpCas9	negative selection	11197928
52364067	52364090	12	-	28162770	OCIAML5	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	-0.3027279798735623	[122]	[179]	-2	hSpCas9	negative selection	11197929
52365089	52365112	12	+	28162770	OCIAML5	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.38010687126503634	[125]	[295]	3	hSpCas9	negative selection	11197930
52364124	52364147	12	-	28162770	OCIAML5	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.5480603839738969	[80]	[99]	-4	hSpCas9	negative selection	11197931
52362324	52362347	12	-	28162770	OCIAML5	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-2.1798712320880287	[122]	[48]	-8	hSpCas9	negative selection	11197932
52367194	52367217	12	+	28162770	OCIAML5	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.10050808294326641	[200]	[388]	0	hSpCas9	negative selection	11197933
52365061	52365084	12	+	28162770	OCIAML5	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.08380309171628753	[321]	[615]	0	hSpCas9	negative selection	11197934
52364318	52364341	12	+	28162770	OCIAML5	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.6343801892160907	[302]	[848]	5	hSpCas9	negative selection	11197935
52364103	52364126	12	-	28162770	OCIAML5	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.8263799272003476	[166]	[169]	-5	hSpCas9	negative selection	11197936
52364089	52364112	12	+	28162770	OCIAML5	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.5485870102521907	[188]	[498]	5	hSpCas9	negative selection	11197937
52367265	52367288	12	-	28162770	EOL1	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	0.5471806902577457	[125]	[96]	5	hSpCas9	negative selection	11367294
52364067	52364090	12	-	28162770	EOL1	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.2754549334296627	[206]	[131]	2	hSpCas9	negative selection	11367295
52365089	52365112	12	+	28162770	EOL1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.038757428448782605	[426]	[218]	0	hSpCas9	negative selection	11367296
52364124	52364147	12	-	28162770	EOL1	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	0.43226727335923026	[210]	[149]	4	hSpCas9	negative selection	11367297
52362324	52362347	12	-	28162770	EOL1	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-1.4197481363452824	[324]	[63]	-7	hSpCas9	negative selection	11367298
52367194	52367217	12	+	28162770	EOL1	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	-0.19851062483380333	[794]	[364]	-1	hSpCas9	negative selection	11367299
52365061	52365084	12	+	28162770	EOL1	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.38057203563027386	[639]	[258]	-3	hSpCas9	negative selection	11367300
52364318	52364341	12	+	28162770	EOL1	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.6666262891303933	[506]	[423]	6	hSpCas9	negative selection	11367301
52364103	52364126	12	-	28162770	EOL1	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.2958422968547656	[239]	[102]	-2	hSpCas9	negative selection	11367302
52364089	52364112	12	+	28162770	EOL1	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.09787937445609635	[375]	[211]	0	hSpCas9	negative selection	11367303
52367265	52367288	12	-	28162770	MOLM13	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	0.9920486032035352	[104]	[150]	7	hSpCas9	negative selection	11536660
52364067	52364090	12	-	28162770	MOLM13	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.14331656540165266	[272]	[217]	1	hSpCas9	negative selection	11536661
52365089	52365112	12	+	28162770	MOLM13	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	1.1336829568787796	[294]	[467]	8	hSpCas9	negative selection	11536662
52364124	52364147	12	-	28162770	MOLM13	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	1.4043242527671125	[173]	[332]	9	hSpCas9	negative selection	11536663
52362324	52362347	12	-	28162770	MOLM13	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-1.7511204003972172	[283]	[60]	-7	hSpCas9	negative selection	11536664
52367194	52367217	12	+	28162770	MOLM13	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.6363098515741886	[532]	[598]	5	hSpCas9	negative selection	11536665
52365061	52365084	12	+	28162770	MOLM13	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	1.0012837300195458	[692]	[1002]	7	hSpCas9	negative selection	11536666
52364318	52364341	12	+	28162770	MOLM13	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.5172554588655585	[631]	[653]	4	hSpCas9	negative selection	11536667
52364103	52364126	12	-	28162770	MOLM13	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	0.39543758719628846	[244]	[232]	3	hSpCas9	negative selection	11536668
52364089	52364112	12	+	28162770	MOLM13	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.1948182139158794	[466]	[294]	-1	hSpCas9	negative selection	11536669
52367265	52367288	12	-	28162770	HEL	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-0.39473587341830574	[116]	[56]	-3	hSpCas9	negative selection	11706026
52364067	52364090	12	-	28162770	HEL	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	-0.967646265600706	[228]	[74]	-5	hSpCas9	negative selection	11706027
52365089	52365112	12	+	28162770	HEL	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	1.3223065330384758	[240]	[385]	9	hSpCas9	negative selection	11706028
52364124	52364147	12	-	28162770	HEL	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	1.3111173409091506	[167]	[266]	9	hSpCas9	negative selection	11706029
52362324	52362347	12	-	28162770	HEL	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-1.9847482853673564	[240]	[38]	-8	hSpCas9	negative selection	11706030
52367194	52367217	12	+	28162770	HEL	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.3306970854301077	[508]	[409]	2	hSpCas9	negative selection	11706031
52365061	52365084	12	+	28162770	HEL	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	0.03072133055807913	[618]	[404]	0	hSpCas9	negative selection	11706032
52364318	52364341	12	+	28162770	HEL	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.3090014348233612	[459]	[364]	2	hSpCas9	negative selection	11706033
52364103	52364126	12	-	28162770	HEL	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.08765410824236308	[218]	[131]	0	hSpCas9	negative selection	11706034
52364089	52364112	12	+	28162770	HEL	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	-0.6479383289025655	[410]	[167]	-4	hSpCas9	negative selection	11706035
52367265	52367288	12	-	28162770	MV411	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	0.21388499107174874	[86]	[84]	1	hSpCas9	negative selection	11875392
52364067	52364090	12	-	28162770	MV411	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.6476780481335387	[146]	[193]	6	hSpCas9	negative selection	11875393
52365089	52365112	12	+	28162770	MV411	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	-0.20221814536564442	[238]	[174]	-1	hSpCas9	negative selection	11875394
52364124	52364147	12	-	28162770	MV411	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	0.37198264872107867	[121]	[132]	3	hSpCas9	negative selection	11875395
52362324	52362347	12	-	28162770	MV411	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-1.9270601804493612	[157]	[34]	-8	hSpCas9	negative selection	11875396
52367194	52367217	12	+	28162770	MV411	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.37908155659324616	[313]	[343]	3	hSpCas9	negative selection	11875397
52365061	52365084	12	+	28162770	MV411	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.5483788263702625	[466]	[268]	-4	hSpCas9	negative selection	11875398
52364318	52364341	12	+	28162770	MV411	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.6972404682222957	[409]	[559]	6	hSpCas9	negative selection	11875399
52364103	52364126	12	-	28162770	MV411	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	0.2800422162147029	[174]	[178]	2	hSpCas9	negative selection	11875400
52364089	52364112	12	+	28162770	MV411	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.7952470530864655	[235]	[344]	7	hSpCas9	negative selection	11875401
52367265	52367288	12	-	28162770	MONOMAC1	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-0.09575351122237197	[54]	[58]	-1	hSpCas9	negative selection	12044758
52364067	52364090	12	-	28162770	MONOMAC1	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	0.28648039010205684	[107]	[150]	3	hSpCas9	negative selection	12044759
52365089	52365112	12	+	28162770	MONOMAC1	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.1984478547978898	[129]	[170]	2	hSpCas9	negative selection	12044760
52364124	52364147	12	-	28162770	MONOMAC1	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.6069126412226187	[92]	[69]	-5	hSpCas9	negative selection	12044761
52362324	52362347	12	-	28162770	MONOMAC1	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-1.8100137239503065	[155]	[50]	-8	hSpCas9	negative selection	12044762
52367194	52367217	12	+	28162770	MONOMAC1	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.36358369328964124	[258]	[381]	3	hSpCas9	negative selection	12044763
52365061	52365084	12	+	28162770	MONOMAC1	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.03915718727783446	[293]	[327]	0	hSpCas9	negative selection	12044764
52364318	52364341	12	+	28162770	MONOMAC1	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	-0.6991310806076209	[295]	[208]	-5	hSpCas9	negative selection	12044765
52364103	52364126	12	-	28162770	MONOMAC1	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.28763939584046033	[114]	[107]	-3	hSpCas9	negative selection	12044766
52364089	52364112	12	+	28162770	MONOMAC1	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.1655332323251546	[202]	[260]	1	hSpCas9	negative selection	12044767
52367265	52367288	12	-	28162770	OCIAML2	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	-1.4997761709016777	[24]	[48]	-7	hSpCas9	negative selection	12214124
52364067	52364090	12	-	28162770	OCIAML2	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	1.2778314077618744	[24]	[335]	9	hSpCas9	negative selection	12214125
52365089	52365112	12	+	28162770	OCIAML2	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	1.255474776292278	[29]	[396]	9	hSpCas9	negative selection	12214126
52364124	52364147	12	-	28162770	OCIAML2	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.36150810286204876	[34]	[150]	-3	hSpCas9	negative selection	12214127
52362324	52362347	12	-	28162770	OCIAML2	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-0.9358530816892218	[38]	[112]	-6	hSpCas9	negative selection	12214128
52367194	52367217	12	+	28162770	OCIAML2	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.5038350826507012	[56]	[447]	5	hSpCas9	negative selection	12214129
52365061	52365084	12	+	28162770	OCIAML2	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.2864909645801479	[100]	[458]	-2	hSpCas9	negative selection	12214130
52364318	52364341	12	+	28162770	OCIAML2	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	0.25599382470258614	[83]	[555]	2	hSpCas9	negative selection	12214131
52364103	52364126	12	-	28162770	OCIAML2	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	0.6869114517443187	[25]	[231]	6	hSpCas9	negative selection	12214132
52364089	52364112	12	+	28162770	OCIAML2	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.5293701747578388	[54]	[439]	5	hSpCas9	negative selection	12214133
52367265	52367288	12	-	28162770	OCIAML3	viability	GAGGGGTGTCCTGCTACCGAGGG	KRT85	ENSG00000135443	0.12588444048310166	[16]	[55]	1	hSpCas9	negative selection	12383490
52364067	52364090	12	-	28162770	OCIAML3	viability	CCTGAGGCGCCTCTATGAAGAGG	KRT85	ENSG00000135443	1.0223678130284546	[52]	[324]	8	hSpCas9	negative selection	12383491
52365089	52365112	12	+	28162770	OCIAML3	viability	GGTTGCTCTCGCAGCAGCGCTGG	KRT85	ENSG00000135443	0.8295918724581047	[62]	[337]	7	hSpCas9	negative selection	12383492
52364124	52364147	12	-	28162770	OCIAML3	viability	CCTGCGGAAATCAGACCTGGAGG	KRT85	ENSG00000135443	-0.2460843369038565	[43]	[111]	-2	hSpCas9	negative selection	12383493
52362324	52362347	12	-	28162770	OCIAML3	viability	CCTGCTCAAGGAGTACCAGGAGG	KRT85	ENSG00000135443	-0.8960361777738208	[44]	[72]	-6	hSpCas9	negative selection	12383494
52367194	52367217	12	+	28162770	OCIAML3	viability	AAGCCACCTACAGCTATCCGGGG	KRT85	ENSG00000135443	0.10070026638033613	[96]	[313]	1	hSpCas9	negative selection	12383495
52365061	52365084	12	+	28162770	OCIAML3	viability	TCGATGTAGCCACTGAACAGTGG	KRT85	ENSG00000135443	-0.14171052247623717	[128]	[352]	-1	hSpCas9	negative selection	12383496
52364318	52364341	12	+	28162770	OCIAML3	viability	GACAAACTCATTCTCTGCTGTGG	KRT85	ENSG00000135443	-0.5470865929366707	[120]	[249]	-4	hSpCas9	negative selection	12383497
52364103	52364126	12	-	28162770	OCIAML3	viability	GGCCAATGTGGAGGCCCTGGTGG	KRT85	ENSG00000135443	-0.0011830218300366568	[60]	[183]	0	hSpCas9	negative selection	12383498
52364089	52364112	12	+	28162770	OCIAML3	viability	GAAGCTAGACTCCTCCACCAGGG	KRT85	ENSG00000135443	0.3240235128895558	[85]	[324]	3	hSpCas9	negative selection	12383499