Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3902
• Symbol:LAG3
• Description:lymphocyte activating 3

DataSource: http://genomecrispr.dkfz.de/#!/results/LAG3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
6772870	6772893	12	-	26472758	Jiyoye	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	1.3472328410495913	[85]	[164]	7	hSpCas9	negative selection	88501
6775340	6775363	12	-	26472758	Jiyoye	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	-0.17778711921528254	[146]	[97]	-1	hSpCas9	negative selection	88502
6773280	6773303	12	-	26472758	Jiyoye	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.23499440612319322	[79]	[70]	1	hSpCas9	negative selection	88503
6773791	6773814	12	+	26472758	Jiyoye	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.07555389041466698	[223]	[177]	0	hSpCas9	negative selection	88504
6773936	6773959	12	-	26472758	Jiyoye	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.5232724464287446	[178]	[193]	4	hSpCas9	negative selection	88505
6774607	6774630	12	-	26472758	Jiyoye	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.5135979273435514	[247]	[130]	-4	hSpCas9	negative selection	88506
6777834	6777857	12	-	26472758	Jiyoye	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-1.9002531436863737	[98]	[19]	-8	hSpCas9	negative selection	88507
6777855	6777878	12	-	26472758	Jiyoye	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-1.1916592937968402	[208]	[68]	-7	hSpCas9	negative selection	88508
6774676	6774699	12	-	26472758	Jiyoye	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.24963410451939327	[57]	[51]	2	hSpCas9	negative selection	88509
6774795	6774818	12	-	26472758	Jiyoye	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-1.0571056367928193	[148]	[53]	-6	hSpCas9	negative selection	88510
6772870	6772893	12	-	26472758	KBM7	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	-0.01972520760186748	[521,401]	[212,211]	0	hSpCas9	negative selection	279619
6775340	6775363	12	-	26472758	KBM7	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	-0.3211681687703263	[699,415]	[279,138]	-3	hSpCas9	negative selection	279620
6773280	6773303	12	-	26472758	KBM7	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-0.49247342054145166	[496,280]	[193,66]	-4	hSpCas9	negative selection	279621
6773791	6773814	12	+	26472758	KBM7	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.16736848010007432	[1257,723]	[569,458]	1	hSpCas9	negative selection	279622
6773936	6773959	12	-	26472758	KBM7	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.8279418505637629	[871,809]	[660,739]	8	hSpCas9	negative selection	279623
6774607	6774630	12	-	26472758	KBM7	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.07228157037437472	[570,333]	[170,221]	0	hSpCas9	negative selection	279624
6777834	6777857	12	-	26472758	KBM7	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-1.0732748251406647	[260,287]	[62,60]	-7	hSpCas9	negative selection	279625
6777855	6777878	12	-	26472758	KBM7	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-1.060896956433457	[703,725]	[120,198]	-7	hSpCas9	negative selection	279626
6774676	6774699	12	-	26472758	KBM7	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.6059706774057553	[292,294]	[113,70]	-5	hSpCas9	negative selection	279627
6774795	6774818	12	-	26472758	KBM7	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	0.21000144717556612	[394,407]	[204,232]	2	hSpCas9	negative selection	279628
6772870	6772893	12	-	26472758	Raji	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.05870968863790989	[210]	[50]	0	hSpCas9	negative selection	470737
6775340	6775363	12	-	26472758	Raji	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.45614781523327724	[244]	[77]	4	hSpCas9	negative selection	470738
6773280	6773303	12	-	26472758	Raji	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-0.24930997767443933	[209]	[40]	-2	hSpCas9	negative selection	470739
6773791	6773814	12	+	26472758	Raji	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.2964173597636164	[399]	[113]	3	hSpCas9	negative selection	470740
6773936	6773959	12	-	26472758	Raji	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.8454134564349156	[270]	[112]	7	hSpCas9	negative selection	470741
6774607	6774630	12	-	26472758	Raji	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.30591891253449666	[276]	[51]	-3	hSpCas9	negative selection	470742
6777834	6777857	12	-	26472758	Raji	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-2.593056182767493	[181]	[6]	-9	hSpCas9	negative selection	470743
6777855	6777878	12	-	26472758	Raji	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.8519744801290545	[349]	[44]	-6	hSpCas9	negative selection	470744
6774676	6774699	12	-	26472758	Raji	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.17953332112943504	[155]	[40]	1	hSpCas9	negative selection	470745
6774795	6774818	12	-	26472758	Raji	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	0.5144282438989125	[180]	[59]	5	hSpCas9	negative selection	470746
6772870	6772893	12	-	26472758	K562	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.5672863830174237	[306]	[383]	4	hSpCas9	negative selection	661855
6775340	6775363	12	-	26472758	K562	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	1.2309982119041252	[431]	[855]	9	hSpCas9	negative selection	661856
6773280	6773303	12	-	26472758	K562	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-1.1526522250829483	[265]	[100]	-6	hSpCas9	negative selection	661857
6773791	6773814	12	+	26472758	K562	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	-0.46628121180595367	[634]	[387]	-3	hSpCas9	negative selection	661858
6773936	6773959	12	-	26472758	K562	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	1.2050562953956732	[482]	[939]	8	hSpCas9	negative selection	661859
6774607	6774630	12	-	26472758	K562	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.4203228470337071	[473]	[298]	-3	hSpCas9	negative selection	661860
6777834	6777857	12	-	26472758	K562	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-4.74552760766963	[285]	[8]	-9	hSpCas9	negative selection	661861
6777855	6777878	12	-	26472758	K562	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-2.704955199263585	[447]	[57]	-8	hSpCas9	negative selection	661862
6774676	6774699	12	-	26472758	K562	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.007882124009729208	[204]	[173]	0	hSpCas9	negative selection	661863
6774795	6774818	12	-	26472758	K562	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.16249089072899658	[235]	[177]	-1	hSpCas9	negative selection	661864
6773843	6773866	12	-	26627737	DLD1	viability	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.29747624463914124	[866]	[267,226,173]	-3	hSpCas9	negative selection	785308
6774680	6774703	12	+	26627737	DLD1	viability	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.2618243330421338	[861]	[251,405,315]	2	hSpCas9	negative selection	785309
6775412	6775435	12	-	26627737	DLD1	viability	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.03144249585262893	[974]	[330,438,188]	0	hSpCas9	negative selection	785310
6777436	6777459	12	+	26627737	DLD1	viability	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.4669211406799506	[550]	[168,125,84]	-5	hSpCas9	negative selection	785311
6777876	6777899	12	-	26627737	DLD1	viability	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.6303191189219999	[496]	[184,216,307]	6	hSpCas9	negative selection	785312
6778273	6778296	12	+	26627737	DLD1	viability	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.9129771910835411	[199]	[194,85,76]	8	hSpCas9	negative selection	785313
6773843	6773866	12	-	26627737	GBM cells	viability after 5 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.4143937374293321	[291]	[116,117]	-6	hSpCas9	negative selection	867623
6774680	6774703	12	+	26627737	GBM cells	viability after 5 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.36091485313511606	[407]	[287,273]	5	hSpCas9	negative selection	867624
6775412	6775435	12	-	26627737	GBM cells	viability after 5 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.5990202916412386	[332]	[249,290]	8	hSpCas9	negative selection	867625
6777436	6777459	12	+	26627737	GBM cells	viability after 5 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.014391092305621467	[203]	[123,96]	0	hSpCas9	negative selection	867626
6777876	6777899	12	-	26627737	GBM cells	viability after 5 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.232759665233763	[433]	[269,276]	3	hSpCas9	negative selection	867627
6778273	6778296	12	+	26627737	GBM cells	viability after 5 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.40202462161855457	[138]	[108,87]	6	hSpCas9	negative selection	867628
6773843	6773866	12	-	26627737	GBM cells	viability after 13 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.739541755570577	[291]	[79,106]	-7	hSpCas9	negative selection	949938
6774680	6774703	12	+	26627737	GBM cells	viability after 13 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.5039268629801053	[407]	[362,273]	6	hSpCas9	negative selection	949939
6775412	6775435	12	-	26627737	GBM cells	viability after 13 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.5030976476328235	[332]	[324,199]	6	hSpCas9	negative selection	949940
6777436	6777459	12	+	26627737	GBM cells	viability after 13 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.37681872936040406	[203]	[87,82]	-4	hSpCas9	negative selection	949941
6777876	6777899	12	-	26627737	GBM cells	viability after 13 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.32914488796241315	[433]	[286,302]	4	hSpCas9	negative selection	949942
6778273	6778296	12	+	26627737	GBM cells	viability after 13 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.3332409693079792	[138]	[126,68]	4	hSpCas9	negative selection	949943
6773843	6773866	12	-	26627737	GBM cells	viability after 21 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.22827057090754801	[291]	[148,122]	-2	hSpCas9	negative selection	1032253
6774680	6774703	12	+	26627737	GBM cells	viability after 21 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.514730398346396	[407]	[323,309]	5	hSpCas9	negative selection	1032254
6775412	6775435	12	-	26627737	GBM cells	viability after 21 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.9760929711804718	[332]	[346,363]	8	hSpCas9	negative selection	1032255
6777436	6777459	12	+	26627737	GBM cells	viability after 21 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.20918487375664394	[203]	[136,119]	2	hSpCas9	negative selection	1032256
6777876	6777899	12	-	26627737	GBM cells	viability after 21 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.5268938491436158	[433]	[357,322]	5	hSpCas9	negative selection	1032257
6778273	6778296	12	+	26627737	GBM cells	viability after 21 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	-0.8139349472262878	[138]	[43,41]	-6	hSpCas9	negative selection	1032258
6773843	6773866	12	-	26627737	RPE1	viability after 9 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.4759547400007995	[1308]	[336,239]	-3	hSpCas9	negative selection	1114568
6774680	6774703	12	+	26627737	RPE1	viability after 9 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.0793084439012095	[1513]	[328,602]	0	hSpCas9	negative selection	1114569
6775412	6775435	12	-	26627737	RPE1	viability after 9 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.1848607432917766	[901]	[448,890]	7	hSpCas9	negative selection	1114570
6777436	6777459	12	+	26627737	RPE1	viability after 9 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.122907445257888	[698]	[291,168]	0	hSpCas9	negative selection	1114571
6777876	6777899	12	-	26627737	RPE1	viability after 9 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.01870664426195967	[2026]	[641,643]	0	hSpCas9	negative selection	1114572
6778273	6778296	12	+	26627737	RPE1	viability after 9 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	2.345513549594379	[69]	[51,187]	9	hSpCas9	negative selection	1114573
6773843	6773866	12	-	26627737	RPE1	viability after 12 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.745463588117522	[1308]	[286,127]	-5	hSpCas9	negative selection	1196883
6774680	6774703	12	+	26627737	RPE1	viability after 12 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.23269523246218793	[1513]	[317,375]	-1	hSpCas9	negative selection	1196884
6775412	6775435	12	-	26627737	RPE1	viability after 12 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.2993333486089298	[901]	[593,598]	7	hSpCas9	negative selection	1196885
6777436	6777459	12	+	26627737	RPE1	viability after 12 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.12198741643482378	[698]	[191,151]	-1	hSpCas9	negative selection	1196886
6777876	6777899	12	-	26627737	RPE1	viability after 12 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.19506150247224197	[2026]	[586,661]	1	hSpCas9	negative selection	1196887
6778273	6778296	12	+	26627737	RPE1	viability after 12 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	1.507139221023989	[69]	[34,72]	8	hSpCas9	negative selection	1196888
6773843	6773866	12	-	26627737	RPE1	viability after 15 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.9159599802824763	[1308]	[125,263]	-5	hSpCas9	negative selection	1279198
6774680	6774703	12	+	26627737	RPE1	viability after 15 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.6356866950774409	[1513]	[266,283]	-4	hSpCas9	negative selection	1279199
6775412	6775435	12	-	26627737	RPE1	viability after 15 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.0058294881859635	[901]	[237,776]	6	hSpCas9	negative selection	1279200
6777436	6777459	12	+	26627737	RPE1	viability after 15 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.5074911025173083	[698]	[275,285]	3	hSpCas9	negative selection	1279201
6777876	6777899	12	-	26627737	RPE1	viability after 15 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.21951633603944276	[2026]	[772,565]	1	hSpCas9	negative selection	1279202
6778273	6778296	12	+	26627737	RPE1	viability after 15 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	2.076639153292377	[69]	[81,84]	8	hSpCas9	negative selection	1279203
6773843	6773866	12	-	26627737	RPE1	viability after 18 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.028214945146151527	[1308]	[343,348]	0	hSpCas9	negative selection	1361513
6774680	6774703	12	+	26627737	RPE1	viability after 18 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.05046975680606913	[1513]	[482,299]	0	hSpCas9	negative selection	1361514
6775412	6775435	12	-	26627737	RPE1	viability after 18 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.2024315468003055	[901]	[477,647]	7	hSpCas9	negative selection	1361515
6777436	6777459	12	+	26627737	RPE1	viability after 18 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.16453229348786885	[698]	[252,166]	1	hSpCas9	negative selection	1361516
6777876	6777899	12	-	26627737	RPE1	viability after 18 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	-0.44013063435323707	[2026]	[335,474]	-3	hSpCas9	negative selection	1361517
6778273	6778296	12	+	26627737	RPE1	viability after 18 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	-0.07349333008302406	[69]	[1,34]	0	hSpCas9	negative selection	1361518
6773843	6773866	12	-	26627737	HeLa	viability after 8 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.047163850052197365	[627]	[343,247,221]	0	hSpCas9	negative selection	1443828
6774680	6774703	12	+	26627737	HeLa	viability after 8 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.499633904705428	[669]	[541,367,358]	4	hSpCas9	negative selection	1443829
6775412	6775435	12	-	26627737	HeLa	viability after 8 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	-0.3609812812841684	[549]	[408,100,103]	-4	hSpCas9	negative selection	1443830
6777436	6777459	12	+	26627737	HeLa	viability after 8 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.4467263003989137	[702]	[310,269,118]	-4	hSpCas9	negative selection	1443831
6777876	6777899	12	-	26627737	HeLa	viability after 8 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.9635965323893222	[392]	[472,384,183]	7	hSpCas9	negative selection	1443832
6778273	6778296	12	+	26627737	HeLa	viability after 8 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	2.3160778782532145	[82]	[314,158,100]	9	hSpCas9	negative selection	1443833
6773843	6773866	12	-	26627737	HeLa	viability after 12 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.4564801171454942	[627]	[336,344,386]	4	hSpCas9	negative selection	1526143
6774680	6774703	12	+	26627737	HeLa	viability after 12 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.53877840062854	[669]	[317,404,480]	4	hSpCas9	negative selection	1526144
6775412	6775435	12	-	26627737	HeLa	viability after 12 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.3170396485506264	[549]	[200,283,361]	2	hSpCas9	negative selection	1526145
6777436	6777459	12	+	26627737	HeLa	viability after 12 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.9867260190002766	[702]	[239,94,112]	-7	hSpCas9	negative selection	1526146
6777876	6777899	12	-	26627737	HeLa	viability after 12 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.4640420754265696	[392]	[173,248,244]	4	hSpCas9	negative selection	1526147
6778273	6778296	12	+	26627737	HeLa	viability after 12 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	1.9621388498705432	[82]	[206,124,71]	9	hSpCas9	negative selection	1526148
6773843	6773866	12	-	26627737	HeLa	viability after 15 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.031239832173002857	[627]	[213,117,432]	0	hSpCas9	negative selection	1608458
6774680	6774703	12	+	26627737	HeLa	viability after 15 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.5632807025874346	[669]	[376,470,357]	4	hSpCas9	negative selection	1608459
6775412	6775435	12	-	26627737	HeLa	viability after 15 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.4462600678003209	[549]	[231,368,315]	3	hSpCas9	negative selection	1608460
6777436	6777459	12	+	26627737	HeLa	viability after 15 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.1964655584557481	[702]	[501,78,157]	-2	hSpCas9	negative selection	1608461
6777876	6777899	12	-	26627737	HeLa	viability after 15 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.5009671119413749	[392]	[120,267,296]	4	hSpCas9	negative selection	1608462
6778273	6778296	12	+	26627737	HeLa	viability after 15 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.5624812082795347	[82]	[46,97,0]	4	hSpCas9	negative selection	1608463
6773843	6773866	12	-	26627737	HeLa	viability after 18 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.024592911516816085	[627]	[143,99,432]	0	hSpCas9	negative selection	1690773
6774680	6774703	12	+	26627737	HeLa	viability after 18 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.585278258352199	[669]	[260,394,357]	5	hSpCas9	negative selection	1690774
6775412	6775435	12	-	26627737	HeLa	viability after 18 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.4259447122321509	[549]	[158,290,315]	3	hSpCas9	negative selection	1690775
6777436	6777459	12	+	26627737	HeLa	viability after 18 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.1352911224540304	[702]	[354,68,157]	-1	hSpCas9	negative selection	1690776
6777876	6777899	12	-	26627737	HeLa	viability after 18 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.5123358787339494	[392]	[78,228,296]	4	hSpCas9	negative selection	1690777
6778273	6778296	12	+	26627737	HeLa	viability after 18 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.47275818269328806	[82]	[24,81,0]	4	hSpCas9	negative selection	1690778
6773843	6773866	12	-	26627737	HCT116	viability after 6 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.8779693650405125	[2089]	[288,117]	-5	hSpCas9	negative selection	1773088
6774680	6774703	12	+	26627737	HCT116	viability after 6 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.02317058752928558	[1514]	[390,147]	0	hSpCas9	negative selection	1773089
6775412	6775435	12	-	26627737	HCT116	viability after 6 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	2.5441166866693887	[413]	[231,460]	9	hSpCas9	negative selection	1773090
6777436	6777459	12	+	26627737	HCT116	viability after 6 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	1.1813405856593162	[598]	[54,300]	6	hSpCas9	negative selection	1773091
6777876	6777899	12	-	26627737	HCT116	viability after 6 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	1.7313866191706453	[568]	[588,135]	8	hSpCas9	negative selection	1773092
6778273	6778296	12	+	26627737	HCT116	viability after 6 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	2.0565208810311666	[253]	[343,67]	8	hSpCas9	negative selection	1773093
6773843	6773866	12	-	26627737	HCT116	viability after 8 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.014957208878314532	[668]	[432,352,332]	0	hSpCas9	negative selection	1855403
6774680	6774703	12	+	26627737	HCT116	viability after 8 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.6892594346216918	[840]	[322,266,272]	-7	hSpCas9	negative selection	1855404
6775412	6775435	12	-	26627737	HCT116	viability after 8 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.3758511459360052	[185]	[364,273,161]	9	hSpCas9	negative selection	1855405
6777436	6777459	12	+	26627737	HCT116	viability after 8 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.656833807201233	[521]	[214,158,173]	-7	hSpCas9	negative selection	1855406
6777876	6777899	12	-	26627737	HCT116	viability after 8 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.21943353996262488	[415]	[301,291,207]	2	hSpCas9	negative selection	1855407
6778273	6778296	12	+	26627737	HCT116	viability after 8 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	-0.3217907796956919	[261]	[47,155,140]	-4	hSpCas9	negative selection	1855408
6773843	6773866	12	-	26627737	HCT116	viability after 9 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.36379472965216064	[2089]	[574,321]	-3	hSpCas9	negative selection	1937718
6774680	6774703	12	+	26627737	HCT116	viability after 9 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.15046207022966662	[1514]	[607,171]	-1	hSpCas9	negative selection	1937719
6775412	6775435	12	-	26627737	HCT116	viability after 9 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.707609883019868	[413]	[307,402]	9	hSpCas9	negative selection	1937720
6777436	6777459	12	+	26627737	HCT116	viability after 9 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.9109877416665385	[598]	[140,426]	6	hSpCas9	negative selection	1937721
6777876	6777899	12	-	26627737	HCT116	viability after 9 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.5985340389191267	[568]	[281,188]	4	hSpCas9	negative selection	1937722
6778273	6778296	12	+	26627737	HCT116	viability after 9 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.9949488058926665	[253]	[185,94]	7	hSpCas9	negative selection	1937723
6773843	6773866	12	-	26627737	HCT116	viability after 12 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.7134942940595652	[668]	[688,508,519]	6	hSpCas9	negative selection	2020033
6774680	6774703	12	+	26627737	HCT116	viability after 12 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.10244286461966179	[840]	[402,296,532]	-1	hSpCas9	negative selection	2020034
6775412	6775435	12	-	26627737	HCT116	viability after 12 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.445313598356225	[185]	[331,274,185]	9	hSpCas9	negative selection	2020035
6777436	6777459	12	+	26627737	HCT116	viability after 12 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-1.037443263333816	[521]	[101,144,156]	-8	hSpCas9	negative selection	2020036
6777876	6777899	12	-	26627737	HCT116	viability after 12 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	-0.08782855639570569	[415]	[158,278,184]	-1	hSpCas9	negative selection	2020037
6778273	6778296	12	+	26627737	HCT116	viability after 12 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.38804697440272223	[261]	[89,160,296]	4	hSpCas9	negative selection	2020038
6773843	6773866	12	-	26627737	HCT116	viability after 15 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.29631193452466253	[668]	[379,615,408]	3	hSpCas9	negative selection	2102348
6774680	6774703	12	+	26627737	HCT116	viability after 15 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.8119666728472054	[840]	[264,275,282]	-7	hSpCas9	negative selection	2102349
6775412	6775435	12	-	26627737	HCT116	viability after 15 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.512805133390657	[185]	[446,281,203]	9	hSpCas9	negative selection	2102350
6777436	6777459	12	+	26627737	HCT116	viability after 15 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-1.3646063490071447	[521]	[159,114,79]	-8	hSpCas9	negative selection	2102351
6777876	6777899	12	-	26627737	HCT116	viability after 15 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	-0.23432602506965444	[415]	[220,232,157]	-2	hSpCas9	negative selection	2102352
6778273	6778296	12	+	26627737	HCT116	viability after 15 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.3603216155198054	[261]	[74,206,281]	3	hSpCas9	negative selection	2102353
6773843	6773866	12	-	26627737	HCT116	viability after 18 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.5423108220793698	[668]	[409,444,563]	4	hSpCas9	negative selection	2184663
6774680	6774703	12	+	26627737	HCT116	viability after 18 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.29971506631661793	[840]	[419,292,277]	-3	hSpCas9	negative selection	2184664
6775412	6775435	12	-	26627737	HCT116	viability after 18 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	1.4228119150500538	[185]	[325,139,264]	8	hSpCas9	negative selection	2184665
6777436	6777459	12	+	26627737	HCT116	viability after 18 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-1.327624594190254	[521]	[161,37,105]	-8	hSpCas9	negative selection	2184666
6777876	6777899	12	-	26627737	HCT116	viability after 18 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	-0.2739681337172326	[415]	[133,170,194]	-3	hSpCas9	negative selection	2184667
6778273	6778296	12	+	26627737	HCT116	viability after 18 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.12608348773800043	[261]	[91,68,263]	1	hSpCas9	negative selection	2184668
6774605	6774628	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGGCTCTGAGAGATCCTGGGGGG	LAG3	ENSG00000089692	-0.33592329986962777	[2,2]	[3,0]	-5	hSpCas9	positive selection	2998749
6773280	6773303	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.19949394373315937	[4,4]	[5,4]	4	hSpCas9	positive selection	2998750
6773936	6773959	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	-0.1979281154895249	[3,3]	[4,0]	-3	hSpCas9	positive selection	2998751
6774676	6774699	12	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.20003487453184893	[3,3]	[3,2]	4	hSpCas9	positive selection	2998752
6774605	6774628	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGGCTCTGAGAGATCCTGGGGGG	LAG3	ENSG00000089692	-1.1537724759876578	[2,2]	[0,0]	-9	hSpCas9	positive selection	3066607
6773280	6773303	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.456615102038083	[4,4]	[4,4]	7	hSpCas9	positive selection	3066608
6773936	6773959	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	-0.6207459592042106	[3,3]	[2,0]	-8	hSpCas9	positive selection	3066609
6774676	6774699	12	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.0053411681180437764	[3,3]	[2,1]	0	hSpCas9	positive selection	3066610
6773907	6773930		-	24336571	A375	resistance to PLX after 7 days	ACTCGCCGGCGTCCGCGCGCCGG	LAG3	ENSG00000089692	0.23245512238669117	[9,11]	[12,11]	6	hSpCas9	positive selection	3124039
6773991	6774014		-	24336571	A375	resistance to PLX after 7 days	CGCCCCACATACTCGAGGCCTGG	LAG3	ENSG00000089692	-0.13962736521736124	[13,17]	[14,13]	-4	hSpCas9	positive selection	3124040
6773270	6773293		-	24336571	A375	resistance to PLX after 7 days	GAGATCCTGGAGGGGGATTGTGG	LAG3	ENSG00000089692	-0.42961485061499927	[13,14]	[8,11]	-9	hSpCas9	positive selection	3124041
6773295	6773318		-	24336571	A375	resistance to PLX after 7 days	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.13665590475750466	[17,16]	[13,16]	-4	hSpCas9	positive selection	3124042
6773907	6773930		-	24336571	A375	resistance to PLX after 14 days	ACTCGCCGGCGTCCGCGCGCCGG	LAG3	ENSG00000089692	0.06735187816889693	[10,13]	[5,5]	0	hSpCas9	positive selection	3181832
6773991	6774014		-	24336571	A375	resistance to PLX after 14 days	CGCCCCACATACTCGAGGCCTGG	LAG3	ENSG00000089692	0.27284966588075993	[12,18]	[8,7]	2	hSpCas9	positive selection	3181833
6773270	6773293		-	24336571	A375	resistance to PLX after 14 days	GAGATCCTGGAGGGGGATTGTGG	LAG3	ENSG00000089692	-0.33761751416832914	[14,9]	[3,4]	-4	hSpCas9	positive selection	3181834
6773295	6773318		-	24336571	A375	resistance to PLX after 14 days	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.41340842723441773	[23,12]	[9,11]	4	hSpCas9	positive selection	3181835
6773907	6773930		-	24336571	A375	viability after 7 days	ACTCGCCGGCGTCCGCGCGCCGG	LAG3	ENSG00000089692	0.17809523270584177	[9]	[9,11]	2	hSpCas9	negative selection	3239625
6773991	6774014		-	24336571	A375	viability after 7 days	CGCCCCACATACTCGAGGCCTGG	LAG3	ENSG00000089692	0.49232705256728726	[11]	[13,17]	7	hSpCas9	negative selection	3239626
6773270	6773293		-	24336571	A375	viability after 7 days	GAGATCCTGGAGGGGGATTGTGG	LAG3	ENSG00000089692	0.2606073190958241	[12]	[13,14]	4	hSpCas9	negative selection	3239627
6773295	6773318		-	24336571	A375	viability after 7 days	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.07816067680620326	[16]	[17,16]	1	hSpCas9	negative selection	3239628
6773907	6773930		-	24336571	A375	viability after 14 days	ACTCGCCGGCGTCCGCGCGCCGG	LAG3	ENSG00000089692	0.3779971570873646	[9]	[10,13]	5	hSpCas9	negative selection	3297418
6773991	6774014		-	24336571	A375	viability after 14 days	CGCCCCACATACTCGAGGCCTGG	LAG3	ENSG00000089692	0.48043282532307674	[11]	[12,18]	6	hSpCas9	negative selection	3297419
6773270	6773293		-	24336571	A375	viability after 14 days	GAGATCCTGGAGGGGGATTGTGG	LAG3	ENSG00000089692	0.036588255048932844	[12]	[14,9]	0	hSpCas9	negative selection	3297420
6773295	6773318		-	24336571	A375	viability after 14 days	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.20920365368005056	[16]	[23,12]	2	hSpCas9	negative selection	3297421
6773295	6773318	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	3.7810699701671786	[344,344]	[30,30]	9	hSpCas9	positive selection	3376672
6773919	6773942	12	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.7495315712471388	[90,90]	[0,0]	3	hSpCas9	positive selection	3376673
6774652	6774675	12	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	1.1912370209880627	[66,66]	[0,0]	5	hSpCas9	positive selection	3376674
6774605	6774628	12	-	26780180	HT29	viability (Avana library 4 designs)	AGGCTCTGAGAGATCCTGGGGGG	LAG3	ENSG00000089692	2.06147633861066	[]	[]	7	hSpCas9	negative selection	3436253
6773280	6773303	12	-	26780180	HT29	viability (Avana library 4 designs)	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.322378464559123	[]	[]	1	hSpCas9	negative selection	3436254
6773936	6773959	12	-	26780180	HT29	viability (Avana library 4 designs)	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.939600256902177	[]	[]	3	hSpCas9	negative selection	3436255
6774676	6774699	12	-	26780180	HT29	viability (Avana library 4 designs)	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	1.03330397383123	[]	[]	4	hSpCas9	negative selection	3436256
6773936	6773959	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	4.73615548213574	[]	[]	7	hSpCas9	negative selection	3524349
6774676	6774699	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.707691814910227	[]	[]	-1	hSpCas9	negative selection	3524350
6774605	6774628	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	AGGCTCTGAGAGATCCTGGGGGG	LAG3	ENSG00000089692	1.57349613736365	[]	[]	2	hSpCas9	negative selection	3524351
6773280	6773303	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	2.00760024140188	[]	[]	3	hSpCas9	negative selection	3524352
6773895	6773918	12	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGCGCCCAGCCCGGCGCGCGG	LAG3	ENSG00000089692	5.06392984016619	[]	[]	8	hSpCas9	negative selection	3524353
6774625	6774648	12	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTTCAAAATGACCCAGTCGGAGG	LAG3	ENSG00000089692	0.671529271701247	[]	[]	0	hSpCas9	negative selection	3524354
6773936	6773959	12	-	26780180	A375	viability (Avana lentiGuide)	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.909272211828226	[]	[]	1	hSpCas9	negative selection	3633008
6774676	6774699	12	-	26780180	A375	viability (Avana lentiGuide)	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-1.83893955753023	[]	[]	-3	hSpCas9	negative selection	3633009
6774605	6774628	12	-	26780180	A375	viability (Avana lentiGuide)	AGGCTCTGAGAGATCCTGGGGGG	LAG3	ENSG00000089692	10.1729700237723	[]	[]	7	hSpCas9	negative selection	3633010
6773280	6773303	12	-	26780180	A375	viability (Avana lentiGuide)	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	5.35230363293826	[]	[]	5	hSpCas9	negative selection	3633011
6773895	6773918	12	+	26780180	A375	viability (Avana lentiGuide)	GCTGCGCCCAGCCCGGCGCGCGG	LAG3	ENSG00000089692	-3.17579676155886	[]	[]	-5	hSpCas9	negative selection	3633012
6774625	6774648	12	-	26780180	A375	viability (Avana lentiGuide)	GTTCAAAATGACCCAGTCGGAGG	LAG3	ENSG00000089692	7.57568387421332	[]	[]	6	hSpCas9	negative selection	3633013
6773936	6773959	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.2286421534776229	[5]	[5,5]	6	hSpCas9	positive selection	3741667
6774676	6774699	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.15118469479695953	[4]	[3,4]	-2	hSpCas9	positive selection	3741668
6774605	6774628	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGGCTCTGAGAGATCCTGGGGGG	LAG3	ENSG00000089692	0.08106908531361001	[3]	[3,3]	2	hSpCas9	positive selection	3741669
6773280	6773303	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.1417731287295778	[5]	[6,5]	4	hSpCas9	positive selection	3741670
6773895	6773918	12	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGCGCCCAGCCCGGCGCGCGG	LAG3	ENSG00000089692	0.46825369509973924	[4]	[6,6]	9	hSpCas9	positive selection	3741671
6774625	6774648	12	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTCAAAATGACCCAGTCGGAGG	LAG3	ENSG00000089692	0.1585020597621724	[4]	[5,4]	4	hSpCas9	positive selection	3741672
6773936	6773959	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	-0.1417720935621944	[5]	[4,4]	-2	hSpCas9	positive selection	3850274
6774676	6774699	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.1644486391556364	[4]	[4,2]	-2	hSpCas9	positive selection	3850275
6774605	6774628	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGGCTCTGAGAGATCCTGGGGGG	LAG3	ENSG00000089692	-0.08751433905424932	[3]	[3,2]	-1	hSpCas9	positive selection	3850276
6773280	6773303	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.1945193343525476	[6]	[6,6]	5	hSpCas9	positive selection	3850277
6773895	6773918	12	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGCGCCCAGCCCGGCGCGCGG	LAG3	ENSG00000089692	0.2852730314499066	[6]	[6,6]	7	hSpCas9	positive selection	3850278
6774625	6774648	12	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTCAAAATGACCCAGTCGGAGG	LAG3	ENSG00000089692	-0.38881917482185024	[5]	[3,2]	-5	hSpCas9	positive selection	3850279
6773919	6773942	12	+	26780180	A375	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	1.01973588278571	[]	[]	5	hSpCas9	negative selection	3956072
6773868	6773891	12	-	26780180	A375	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	1.237380334063	[]	[]	6	hSpCas9	negative selection	3956073
6774676	6774699	12	-	26780180	A375	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.900213034052588	[]	[]	4	hSpCas9	negative selection	3956074
6777784	6777807	12	+	26780180	A375	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	1.57666863655832	[]	[]	8	hSpCas9	negative selection	3956075
6773295	6773318	12	-	26780180	A375	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	1.17481693839376	[]	[]	6	hSpCas9	negative selection	3956076
6774652	6774675	12	-	26780180	A375	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	1.0419839629188	[]	[]	5	hSpCas9	negative selection	3956077
6773919	6773942	12	+	26780180	HT29	viability (GeCKOv2 library)	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	1.29504861766113	[]	[]	6	hSpCas9	negative selection	4064038
6773868	6773891	12	-	26780180	HT29	viability (GeCKOv2 library)	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	1.25491160419039	[]	[]	6	hSpCas9	negative selection	4064039
6774676	6774699	12	-	26780180	HT29	viability (GeCKOv2 library)	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.70386604585871	[]	[]	2	hSpCas9	negative selection	4064040
6777784	6777807	12	+	26780180	HT29	viability (GeCKOv2 library)	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	2.11552328792309	[]	[]	9	hSpCas9	negative selection	4064041
6773295	6773318	12	-	26780180	HT29	viability (GeCKOv2 library)	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.865401082278951	[]	[]	3	hSpCas9	negative selection	4064042
6774652	6774675	12	-	26780180	HT29	viability (GeCKOv2 library)	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.729853093095848	[]	[]	3	hSpCas9	negative selection	4064043
6773907	6773930	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTCGCCGGCGTCCGCGCGCCGG	LAG3	ENSG00000089692	0.07265127689332834	[3]	[2,2]	1	hSpCas9	positive selection	4148041
6773991	6774014	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCCCCACATACTCGAGGCCTGG	LAG3	ENSG00000089692	-0.02859869867291326	[4]	[2,3]	0	hSpCas9	positive selection	4148042
6773270	6773293	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAGATCCTGGAGGGGGATTGTGG	LAG3	ENSG00000089692	-0.23079192626180495	[4]	[2,1]	-5	hSpCas9	positive selection	4148043
6773295	6773318	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.0673063501582793	[4]	[2,3]	1	hSpCas9	positive selection	4148044
6773907	6773930	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTCGCCGGCGTCCGCGCGCCGG	LAG3	ENSG00000089692	1.0467828329490576	[2]	[1,0,2,3]	7	hSpCas9	positive selection	4212063
6773991	6774014	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCCCCACATACTCGAGGCCTGG	LAG3	ENSG00000089692	0.6081468364918887	[2]	[2,0,5,0]	4	hSpCas9	positive selection	4212064
6773270	6773293	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAGATCCTGGAGGGGGATTGTGG	LAG3	ENSG00000089692	-0.25366611771907	[2]	[1,1,0,0]	-4	hSpCas9	positive selection	4212065
6773295	6773318	12	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	1.2808477822023163	[4]	[4,4,2,5]	9	hSpCas9	positive selection	4212066
6777784	6777807	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.5086407236610211	[2]	[2,0]	-8	hSpCas9	positive selection	4279596
6774676	6774699	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.08662373971628196	[2]	[2,0]	-2	hSpCas9	positive selection	4279597
6773868	6773891	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.20814267359111022	[1]	[0,0]	-4	hSpCas9	positive selection	4279598
6773295	6773318	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.17966308779049284	[3]	[3,3]	3	hSpCas9	positive selection	4343853
6773919	6773942	12	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.0801399483682868	[2]	[2,1]	1	hSpCas9	positive selection	4343854
6774652	6774675	12	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.22893548353539628	[1]	[1,0]	-5	hSpCas9	positive selection	4343855
6773842	6773864	12	-	27760321	OCIAML3	viability	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	0.1255621477175346	[857,793]	[617,817]	1	hSpCas9	negative selection	4413631
6773996	6774018	12	-	27760321	OCIAML3	viability	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.2811245451923233	[917,721]	[623,969]	3	hSpCas9	negative selection	4413632
6774682	6774704	12	+	27760321	OCIAML3	viability	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	-0.21544468591580015	[536,475]	[258,446]	-2	hSpCas9	negative selection	4413633
6774716	6774738	12	-	27760321	OCIAML3	viability	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.2901880569994759	[749,519]	[558,653]	3	hSpCas9	negative selection	4413634
6774740	6774762	12	-	27760321	OCIAML3	viability	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.36536208252901065	[301,249]	[278,273]	4	hSpCas9	negative selection	4413635
6773842	6773864	12	-	27760321	OCIAML2	viability	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	-0.06361904303704913	[857,793]	[553,751]	-1	hSpCas9	negative selection	4497094
6773996	6774018	12	-	27760321	OCIAML2	viability	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	-0.2606518059152477	[917,721]	[411,731]	-3	hSpCas9	negative selection	4497095
6774682	6774704	12	+	27760321	OCIAML2	viability	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	-0.004843866042716416	[536,475]	[348,484]	0	hSpCas9	negative selection	4497096
6774716	6774738	12	-	27760321	OCIAML2	viability	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.5132087855360696	[749,519]	[690,768]	7	hSpCas9	negative selection	4497097
6774740	6774762	12	-	27760321	OCIAML2	viability	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.8558564730530345	[301,249]	[359,457]	9	hSpCas9	negative selection	4497098
6773842	6773864	12	-	27760321	MV411	viability	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	-0.7310584281812891	[857,793]	[355,286]	-5	hSpCas9	negative selection	4580557
6773996	6774018	12	-	27760321	MV411	viability	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.2662939195683701	[917,721]	[361,1073]	2	hSpCas9	negative selection	4580558
6774682	6774704	12	+	27760321	MV411	viability	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	-0.49590469629268974	[536,475]	[262,196]	-3	hSpCas9	negative selection	4580559
6774716	6774738	12	-	27760321	MV411	viability	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.257365299241717	[749,519]	[580,365]	1	hSpCas9	negative selection	4580560
6774740	6774762	12	-	27760321	MV411	viability	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	-0.2931539320018115	[301,249]	[123,183]	-2	hSpCas9	negative selection	4580561
6773842	6773864	12	-	27760321	HL60	viability	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	0.33484610831302186	[857,793]	[986,706]	4	hSpCas9	negative selection	4664020
6773996	6774018	12	-	27760321	HL60	viability	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.5307388372245924	[917,721]	[973,947]	6	hSpCas9	negative selection	4664021
6774682	6774704	12	+	27760321	HL60	viability	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	-0.5336819026405588	[536,475]	[279,290]	-5	hSpCas9	negative selection	4664022
6774716	6774738	12	-	27760321	HL60	viability	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.32942554709912186	[749,519]	[717,565]	4	hSpCas9	negative selection	4664023
6774740	6774762	12	-	27760321	HL60	viability	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.5310562403959567	[301,249]	[351,294]	6	hSpCas9	negative selection	4664024
6773842	6773864	12	-	27760321	HT1080	viability	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	-1.3381798442776645	[793,619]	[24,205]	-5	hSpCas9	negative selection	4747483
6773996	6774018	12	-	27760321	HT1080	viability	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.3463400593839778	[721,563]	[244,413]	1	hSpCas9	negative selection	4747484
6774682	6774704	12	+	27760321	HT1080	viability	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	1.6102925699863315	[475,371]	[678,336]	8	hSpCas9	negative selection	4747485
6774716	6774738	12	-	27760321	HT1080	viability	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	-0.5127838871668332	[519,405]	[113,145]	-2	hSpCas9	negative selection	4747486
6774740	6774762	12	-	27760321	HT1080	viability	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	1.4360096201088912	[249,194]	[372,93]	7	hSpCas9	negative selection	4747487
6773842	6773864	12	-	27760321	HT29	viability after 7 days	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	-0.14681759629001134	[793,619]	[1154,735,624]	-2	hSpCas9	negative selection	4830946
6773996	6774018	12	-	27760321	HT29	viability after 7 days	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.6763412643962641	[721,563]	[1320,1168,1466]	8	hSpCas9	negative selection	4830947
6774682	6774704	12	+	27760321	HT29	viability after 7 days	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	0.42055130863028556	[475,371]	[610,635,917]	6	hSpCas9	negative selection	4830948
6774716	6774738	12	-	27760321	HT29	viability after 7 days	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.29830419618127	[519,405]	[718,735,737]	4	hSpCas9	negative selection	4830949
6774740	6774762	12	-	27760321	HT29	viability after 7 days	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.01267826740730904	[249,194]	[407,205,268]	0	hSpCas9	negative selection	4830950
6773842	6773864	12	-	27760321	HT29	viability after 25 days	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	-0.022258058008539527	[793,619]	[691,871,831]	0	hSpCas9	negative selection	4914409
6773996	6774018	12	-	27760321	HT29	viability after 25 days	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.5278785136171773	[721,563]	[1036,904,1256]	6	hSpCas9	negative selection	4914410
6774682	6774704	12	+	27760321	HT29	viability after 25 days	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	-0.08383849852887015	[475,371]	[416,529,422]	-1	hSpCas9	negative selection	4914411
6774716	6774738	12	-	27760321	HT29	viability after 25 days	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.33225272744678547	[519,405]	[427,896,689]	3	hSpCas9	negative selection	4914412
6774740	6774762	12	-	27760321	HT29	viability after 25 days	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.3095257276505348	[249,194]	[329,280,334]	3	hSpCas9	negative selection	4914413
6773842	6773864	12	-	27760321	HT29	viability after 22 days	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	0.05217081789028699	[793,619]	[817,784,940]	0	hSpCas9	negative selection	4997872
6773996	6774018	12	-	27760321	HT29	viability after 22 days	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.7006511546033873	[721,563]	[1228,1280,1112]	7	hSpCas9	negative selection	4997873
6774682	6774704	12	+	27760321	HT29	viability after 22 days	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	0.3532017968280452	[475,371]	[445,643,794]	4	hSpCas9	negative selection	4997874
6774716	6774738	12	-	27760321	HT29	viability after 22 days	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.3646083819472312	[519,405]	[466,967,637]	4	hSpCas9	negative selection	4997875
6774740	6774762	12	-	27760321	HT29	viability after 22 days	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.36138427968876635	[249,194]	[419,222,345]	4	hSpCas9	negative selection	4997876
6773842	6773864	12	-	27760321	HT29	viability after 19 days	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	-0.14589722622302304	[793,619]	[1150,595,497]	-1	hSpCas9	negative selection	5081335
6773996	6774018	12	-	27760321	HT29	viability after 19 days	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.7255042062911639	[721,563]	[1073,1386,1172]	7	hSpCas9	negative selection	5081336
6774682	6774704	12	+	27760321	HT29	viability after 19 days	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	0.01591235275577077	[475,371]	[583,553,347]	0	hSpCas9	negative selection	5081337
6774716	6774738	12	-	27760321	HT29	viability after 19 days	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.33788550381029425	[519,405]	[687,615,703]	3	hSpCas9	negative selection	5081338
6774740	6774762	12	-	27760321	HT29	viability after 19 days	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	1.1317852229896552	[249,194]	[852,149,694]	9	hSpCas9	negative selection	5081339
6773842	6773864	12	-	27760321	HT29	viability after 16 days	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	0.30238051525947085	[793,619]	[946,1149,821]	3	hSpCas9	negative selection	5164798
6773996	6774018	12	-	27760321	HT29	viability after 16 days	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.36210080027110236	[721,563]	[976,841,961]	4	hSpCas9	negative selection	5164799
6774682	6774704	12	+	27760321	HT29	viability after 16 days	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	0.14894413551895178	[475,371]	[594,466,523]	1	hSpCas9	negative selection	5164800
6774716	6774738	12	-	27760321	HT29	viability after 16 days	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.2716684067911308	[519,405]	[781,462,649]	3	hSpCas9	negative selection	5164801
6774740	6774762	12	-	27760321	HT29	viability after 16 days	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.6603281555057521	[249,194]	[311,181,683]	7	hSpCas9	negative selection	5164802
6773842	6773864	12	-	27760321	HT29	viability after 13 days	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	0.1802276293078532	[793,619]	[1464,687,650]	2	hSpCas9	negative selection	5248261
6773996	6774018	12	-	27760321	HT29	viability after 13 days	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.7980445226694881	[721,563]	[1299,1310,1280]	9	hSpCas9	negative selection	5248262
6774682	6774704	12	+	27760321	HT29	viability after 13 days	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	0.16745719690907426	[475,371]	[512,533,606]	2	hSpCas9	negative selection	5248263
6774716	6774738	12	-	27760321	HT29	viability after 13 days	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.5600034829683069	[519,405]	[666,953,756]	7	hSpCas9	negative selection	5248264
6774740	6774762	12	-	27760321	HT29	viability after 13 days	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.6409934907528223	[249,194]	[413,400,392]	8	hSpCas9	negative selection	5248265
6773842	6773864	12	-	27760321	HT29	viability after 10 days	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	0.23911383225812488	[793,619]	[677,1274,1175]	3	hSpCas9	negative selection	5331724
6773996	6774018	12	-	27760321	HT29	viability after 10 days	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.849599172931284	[721,563]	[1567,1631,1151]	9	hSpCas9	negative selection	5331725
6774682	6774704	12	+	27760321	HT29	viability after 10 days	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	0.11094107157550251	[475,371]	[691,594,431]	1	hSpCas9	negative selection	5331726
6774716	6774738	12	-	27760321	HT29	viability after 10 days	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	0.6439553078968094	[519,405]	[988,927,795]	8	hSpCas9	negative selection	5331727
6774740	6774762	12	-	27760321	HT29	viability after 10 days	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	0.019353257362417997	[249,194]	[342,121,372]	0	hSpCas9	negative selection	5331728
6773842	6773864	12	-	27760321	MOLM13	viability	GCTCATCCAGCTGGACGCGGGG	LAG3	ENSG00000089692	-0.1379275508323613	[857,793]	[361,475]	-1	hSpCas9	negative selection	5415187
6773996	6774018	12	-	27760321	MOLM13	viability	GTCCCGCCCCACATACTCGAGG	LAG3	ENSG00000089692	0.9368572949079405	[917,721]	[1432,408]	6	hSpCas9	negative selection	5415188
6774682	6774704	12	+	27760321	MOLM13	viability	TGCATTGGTTCCGGAACCGGGG	LAG3	ENSG00000089692	-0.5100289408205342	[536,475]	[289,123]	-3	hSpCas9	negative selection	5415189
6774716	6774738	12	-	27760321	MOLM13	viability	ATGGGGGGACTCCCGGACAGGG	LAG3	ENSG00000089692	-0.018002001409353707	[749,519]	[339,357]	0	hSpCas9	negative selection	5415190
6774740	6774762	12	-	27760321	MOLM13	viability	GAGGAAGCTTTCCGCTAAGTGG	LAG3	ENSG00000089692	-1.5063660001808161	[301,249]	[93,20]	-7	hSpCas9	negative selection	5415191
6772561	6772584	12	+	27661255	K562	viability	GCTCTGTCTGCTCTCCGCCACGG	LAG3	ENSG00000089692	-0.4768523332758323	[142,99]	[87,54]	-7	dCas9-KRAB	negative selection	5489678
6772899	6772922	12	+	27661255	K562	viability	GGGTGGCTCCAGGTAAAACGGGG	LAG3	ENSG00000089692	0.21323827619531638	[753,759]	[708,693]	7	dCas9-KRAB	negative selection	5489679
6772657	6772680	12	-	27661255	K562	viability	GACCAGAGGCCGGAATCCAGAGG	LAG3	ENSG00000089692	0.12935497249009464	[1344,1216]	[1225,1031]	4	dCas9-KRAB	negative selection	5489680
6772960	6772983	12	-	27661255	K562	viability	GTGGCCACAGAGATCCCTGCTGG	LAG3	ENSG00000089692	0.2285613174499168	[691,860]	[846,618]	7	dCas9-KRAB	negative selection	5489681
6777784	6777807	12	+	27260156	BXPC3	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.04164507122191685	[392]	[370,506,418,387]	0	hSpCas9	negative selection	5552056
6774676	6774699	12	-	27260156	BXPC3	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.2083599260742337	[264]	[321,385,307,248]	4	hSpCas9	negative selection	5552057
6773868	6773891	12	-	27260156	BXPC3	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.28061346005486265	[172]	[101,198,135,160]	-6	hSpCas9	negative selection	5552058
6773295	6773318	12	-	27260156	BXPC3	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.030651218736523766	[834]	[787,829,1061,899]	0	hSpCas9	negative selection	5616313
6773919	6773942	12	+	27260156	BXPC3	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.40556465096860506	[203]	[283,232,305,311]	8	hSpCas9	negative selection	5616314
6774652	6774675	12	-	27260156	BXPC3	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.1449932253214039	[159]	[178,123,166,284]	3	hSpCas9	negative selection	5616315
6777784	6777807	12	+	27260156	A673	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.2642932902090803	[392]	[611,690,448,513]	6	hSpCas9	negative selection	5673307
6774676	6774699	12	-	27260156	A673	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.4805502393184928	[264]	[511,408,476,381]	9	hSpCas9	negative selection	5673308
6773868	6773891	12	-	27260156	A673	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.26835857954851083	[172]	[209,151,181,148]	-6	hSpCas9	negative selection	5673309
6773295	6773318	12	-	27260156	A673	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.029394678739167013	[834]	[1128,953,999,854]	0	hSpCas9	negative selection	5737564
6773919	6773942	12	+	27260156	A673	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.07201098463637612	[203]	[258,220,266,284]	1	hSpCas9	negative selection	5737565
6774652	6774675	12	-	27260156	A673	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.5040192742347667	[159]	[281,265,248,294]	9	hSpCas9	negative selection	5737566
6777784	6777807	12	+	27260156	A375	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.12953397200116587	[392]	[496,707,427,412]	1	hSpCas9	negative selection	5794558
6774676	6774699	12	-	27260156	A375	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.16264913775388545	[264]	[303,430,342,320]	2	hSpCas9	negative selection	5794559
6773868	6773891	12	-	27260156	A375	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.2105218276556151	[172]	[97,268,118,218]	-3	hSpCas9	negative selection	5794560
6773295	6773318	12	-	27260156	A375	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.40924735057982703	[834]	[733,781,650,769]	-5	hSpCas9	negative selection	5858815
6773919	6773942	12	+	27260156	A375	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.16064543995338876	[203]	[212,283,246,127]	-2	hSpCas9	negative selection	5858816
6774652	6774675	12	-	27260156	A375	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.4194566285446828	[159]	[136,158,124,139]	-5	hSpCas9	negative selection	5858817
6777784	6777807	12	+	27260156	COLO741	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.017994556513536653	[392]	[422,597,496]	0	hSpCas9	negative selection	5915809
6774676	6774699	12	-	27260156	COLO741	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.7862998446884771	[264]	[440,647,644]	9	hSpCas9	negative selection	5915810
6773868	6773891	12	-	27260156	COLO741	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.14201703284839873	[172]	[234,315,62]	-3	hSpCas9	negative selection	5915811
6773295	6773318	12	-	27260156	COLO741	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.063527738751051	[834]	[1060,928,1069]	-1	hSpCas9	negative selection	5980066
6773919	6773942	12	+	27260156	COLO741	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.02502156868407046	[203]	[267,313,216]	0	hSpCas9	negative selection	5980067
6774652	6774675	12	-	27260156	COLO741	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.21968323825024072	[159]	[140,200,180]	-5	hSpCas9	negative selection	5980068
6777784	6777807	12	+	27260156	CAL120	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.4864875460358998	[392]	[342,402,300]	-6	hSpCas9	negative selection	6037060
6774676	6774699	12	-	27260156	CAL120	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.23881956105413815	[264]	[455,427,294]	3	hSpCas9	negative selection	6037061
6773868	6773891	12	-	27260156	CAL120	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.21166925772133371	[172]	[460,200,119]	3	hSpCas9	negative selection	6037062
6773295	6773318	12	-	27260156	CAL120	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.3810018988954503	[834]	[897,911,601]	-5	hSpCas9	negative selection	6101317
6773919	6773942	12	+	27260156	CAL120	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.2106387574045503	[203]	[265,373,237]	3	hSpCas9	negative selection	6101318
6774652	6774675	12	-	27260156	CAL120	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.029317432111062525	[159]	[126,198,247]	0	hSpCas9	negative selection	6101319
6777784	6777807	12	+	27260156	CADOES1	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.1527130843380027	[392]	[340,524,269,492]	2	hSpCas9	negative selection	6158311
6774676	6774699	12	-	27260156	CADOES1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.5542050325733789	[264]	[465,419,313,242]	8	hSpCas9	negative selection	6158312
6773868	6773891	12	-	27260156	CADOES1	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.15363070498566223	[172]	[211,107,147,108]	-3	hSpCas9	negative selection	6158313
6773295	6773318	12	-	27260156	CADOES1	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.18473971284365387	[834]	[813,617,631,667]	-3	hSpCas9	negative selection	6222568
6773919	6773942	12	+	27260156	CADOES1	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.08171829058489744	[203]	[165,249,169,217]	1	hSpCas9	negative selection	6222569
6774652	6774675	12	-	27260156	CADOES1	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.23777302059584016	[159]	[174,205,67,255]	4	hSpCas9	negative selection	6222570
6777784	6777807	12	+	27260156	EWS502	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.2581492562558692	[392]	[360,357,329,338]	-4	hSpCas9	negative selection	6279562
6774676	6774699	12	-	27260156	EWS502	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.5025061668233318	[264]	[287,426,527,356]	8	hSpCas9	negative selection	6279563
6773868	6773891	12	-	27260156	EWS502	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.2983095682863284	[172]	[127,171,148,147]	-5	hSpCas9	negative selection	6279564
6773295	6773318	12	-	27260156	EWS502	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.006605431378703064	[834]	[713,677,967,1246]	0	hSpCas9	negative selection	6343819
6773919	6773942	12	+	27260156	EWS502	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.11246344405351771	[203]	[331,144,243,201]	2	hSpCas9	negative selection	6343820
6774652	6774675	12	-	27260156	EWS502	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.3066956160239842	[159]	[131,183,53,177]	-5	hSpCas9	negative selection	6343821
6777784	6777807	12	+	27260156	EW8	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.24542441368370066	[392]	[374,430,276,442]	4	hSpCas9	negative selection	6400813
6774676	6774699	12	-	27260156	EW8	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.4733731463910328	[264]	[208,331,201,454]	8	hSpCas9	negative selection	6400814
6773868	6773891	12	-	27260156	EW8	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.29065737985440454	[172]	[190,66,68,146]	-5	hSpCas9	negative selection	6400815
6773295	6773318	12	-	27260156	EW8	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.08631319592942621	[834]	[697,683,468,731]	-2	hSpCas9	negative selection	6465070
6773919	6773942	12	+	27260156	EW8	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.3203832575539812	[203]	[294,308,109,137]	6	hSpCas9	negative selection	6465071
6774652	6774675	12	-	27260156	EW8	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.2357271199201063	[159]	[236,141,90,159]	4	hSpCas9	negative selection	6465072
6777784	6777807	12	+	27260156	CORL105	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.3453774883439993	[392]	[520,681,559,566]	6	hSpCas9	negative selection	6522064
6774676	6774699	12	-	27260156	CORL105	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.185857759702717	[264]	[323,277,449,374]	3	hSpCas9	negative selection	6522065
6773868	6773891	12	-	27260156	CORL105	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.3007994679801227	[172]	[311,212,256,219]	5	hSpCas9	negative selection	6522066
6773295	6773318	12	-	27260156	CORL105	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.014006148366573545	[834]	[924,758,1286,1025]	0	hSpCas9	negative selection	6586321
6773919	6773942	12	+	27260156	CORL105	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.24920526964249357	[203]	[298,279,302,256]	4	hSpCas9	negative selection	6586322
6774652	6774675	12	-	27260156	CORL105	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.29328189034078744	[159]	[262,144,312,212]	5	hSpCas9	negative selection	6586323
6777784	6777807	12	+	27260156	HS294T	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.37669038308194486	[392]	[154,213,165,268]	5	hSpCas9	negative selection	6643315
6774676	6774699	12	-	27260156	HS294T	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.3518679592234042	[264]	[70,284,71,87]	5	hSpCas9	negative selection	6643316
6773868	6773891	12	-	27260156	HS294T	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.1708515644466917	[172]	[30,71,63,150]	2	hSpCas9	negative selection	6643317
6773295	6773318	12	-	27260156	HS294T	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.1273157319428031	[834]	[204,292,257,461]	-2	hSpCas9	negative selection	6707572
6773919	6773942	12	+	27260156	HS294T	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.5541412761230868	[203]	[39,60,54,60]	-7	hSpCas9	negative selection	6707573
6774652	6774675	12	-	27260156	HS294T	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.35182890266145184	[159]	[42,29,47,78]	-5	hSpCas9	negative selection	6707574
6777784	6777807	12	+	27260156	HCC44	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.06596713782593994	[392]	[420,479,485,313]	-1	hSpCas9	negative selection	6764566
6774676	6774699	12	-	27260156	HCC44	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.257836510036748	[264]	[214,378,357,458]	4	hSpCas9	negative selection	6764567
6773868	6773891	12	-	27260156	HCC44	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.20680216218141556	[172]	[191,104,172,216]	-3	hSpCas9	negative selection	6764568
6773295	6773318	12	-	27260156	HCC44	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.18019643551391806	[834]	[910,580,921,966]	-3	hSpCas9	negative selection	6828823
6773919	6773942	12	+	27260156	HCC44	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.18846791163129373	[203]	[417,199,237,213]	3	hSpCas9	negative selection	6828824
6774652	6774675	12	-	27260156	HCC44	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.563523433206783	[159]	[234,346,230,234]	8	hSpCas9	negative selection	6828825
6777784	6777807	12	+	27260156	G402	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.8469295975828963	[392]	[439,1024,681,1229]	9	hSpCas9	negative selection	6885817
6774676	6774699	12	-	27260156	G402	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.8434872451327688	[264]	[590,769,321,644]	9	hSpCas9	negative selection	6885818
6773868	6773891	12	-	27260156	G402	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.0219371770098733	[172]	[94,160,330,223]	0	hSpCas9	negative selection	6885819
6773295	6773318	12	-	27260156	G402	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.2520086437095862	[834]	[1501,835,1287,1240]	3	hSpCas9	negative selection	6950074
6773919	6773942	12	+	27260156	G402	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.0814820536891192	[203]	[261,360,150,179]	-1	hSpCas9	negative selection	6950075
6774652	6774675	12	-	27260156	G402	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.00852042632723804	[159]	[196,158,139,273]	0	hSpCas9	negative selection	6950076
6777784	6777807	12	+	27260156	L33	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.5147604468239295	[392]	[485,242,406,521]	8	hSpCas9	negative selection	7007068
6774676	6774699	12	-	27260156	L33	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.2627361110875971	[264]	[290,81,152,147]	-6	hSpCas9	negative selection	7007069
6773868	6773891	12	-	27260156	L33	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.007100618527738245	[172]	[161,48,170,135]	0	hSpCas9	negative selection	7007070
6773295	6773318	12	-	27260156	L33	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.17189282066039635	[834]	[1014,418,492,937]	4	hSpCas9	negative selection	7071325
6773919	6773942	12	+	27260156	L33	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.050856758940314606	[203]	[178,90,178,160]	1	hSpCas9	negative selection	7071326
6774652	6774675	12	-	27260156	L33	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.1372041037774785	[159]	[155,94,84,180]	3	hSpCas9	negative selection	7071327
6777784	6777807	12	+	27260156	K562	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.312072505511736	[392]	[199,422,583,495]	4	hSpCas9	negative selection	7128319
6774676	6774699	12	-	27260156	K562	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.3219275502021074	[264]	[148,418,464,152]	4	hSpCas9	negative selection	7128320
6773868	6773891	12	-	27260156	K562	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.4612047540842016	[172]	[66,98,422,234]	6	hSpCas9	negative selection	7128321
6773295	6773318	12	-	27260156	K562	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.7494027455512807	[834]	[418,372,589,380]	-7	hSpCas9	negative selection	7192576
6773919	6773942	12	+	27260156	K562	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.07386125735338944	[203]	[321,90,69,273]	0	hSpCas9	negative selection	7192577
6774652	6774675	12	-	27260156	K562	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.7681692317216643	[159]	[366,307,119,190]	8	hSpCas9	negative selection	7192578
6777784	6777807	12	+	27260156	HT29	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.1682113473686549	[392]	[670,521,490,475]	3	hSpCas9	negative selection	7249570
6774676	6774699	12	-	27260156	HT29	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.43734186361189015	[264]	[445,436,445,415]	8	hSpCas9	negative selection	7249571
6773868	6773891	12	-	27260156	HT29	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.27850149931978185	[172]	[216,286,184,320]	5	hSpCas9	negative selection	7249572
6773295	6773318	12	-	27260156	HT29	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.1751381897050276	[834]	[1236,1195,1078,1082]	3	hSpCas9	negative selection	7313827
6773919	6773942	12	+	27260156	HT29	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.34771768348747745	[203]	[413,243,346,262]	6	hSpCas9	negative selection	7313828
6774652	6774675	12	-	27260156	HT29	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.09058351472364667	[159]	[246,244,203,144]	1	hSpCas9	negative selection	7313829
6777784	6777807	12	+	27260156	MHHES1	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.4274973396952254	[392]	[683,538,553,594]	7	hSpCas9	negative selection	7370821
6774676	6774699	12	-	27260156	MHHES1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.28439394448167343	[264]	[269,724,205,286]	5	hSpCas9	negative selection	7370822
6773868	6773891	12	-	27260156	MHHES1	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.005752474314415057	[172]	[215,257,231,97]	0	hSpCas9	negative selection	7370823
6773295	6773318	12	-	27260156	MHHES1	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.1759787276322512	[834]	[865,1022,887,609]	-3	hSpCas9	negative selection	7435078
6773919	6773942	12	+	27260156	MHHES1	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.03852722959995769	[203]	[188,322,229,166]	0	hSpCas9	negative selection	7435079
6774652	6774675	12	-	27260156	MHHES1	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.06596565269099575	[159]	[359,254,72,107]	1	hSpCas9	negative selection	7435080
6777784	6777807	12	+	27260156	MEWO	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.35247144430189337	[392]	[477,436,494]	7	hSpCas9	negative selection	7492072
6774676	6774699	12	-	27260156	MEWO	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.5751517530492605	[264]	[346,303,452]	9	hSpCas9	negative selection	7492073
6773868	6773891	12	-	27260156	MEWO	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.546728759340888	[172]	[222,160,322]	9	hSpCas9	negative selection	7492074
6773295	6773318	12	-	27260156	MEWO	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.08478278473764145	[834]	[1035,462,769]	-2	hSpCas9	negative selection	7556329
6773919	6773942	12	+	27260156	MEWO	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.3952500495400453	[203]	[353,233,184]	8	hSpCas9	negative selection	7556330
6774652	6774675	12	-	27260156	MEWO	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.21293245507619618	[159]	[117,111,279]	4	hSpCas9	negative selection	7556331
6777784	6777807	12	+	27260156	LNCAPCLONEFGC	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.16266687776287533	[392]	[482,342,487,294]	2	hSpCas9	negative selection	7613323
6774676	6774699	12	-	27260156	LNCAPCLONEFGC	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.7632985898623786	[264]	[282,430,370,539]	9	hSpCas9	negative selection	7613324
6773868	6773891	12	-	27260156	LNCAPCLONEFGC	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.016287306037048976	[172]	[138,168,201,129]	0	hSpCas9	negative selection	7613325
6773295	6773318	12	-	27260156	LNCAPCLONEFGC	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.08598655881400186	[834]	[783,637,782,658]	-1	hSpCas9	negative selection	7677580
6773919	6773942	12	+	27260156	LNCAPCLONEFGC	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.10318007599125756	[203]	[191,150,164,179]	-2	hSpCas9	negative selection	7677581
6774652	6774675	12	-	27260156	LNCAPCLONEFGC	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.0809176725137426	[159]	[158,159,115,171]	1	hSpCas9	negative selection	7677582
6777784	6777807	12	+	27260156	PANC0327	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.9073889809318134	[392]	[203,123,230,194]	-8	hSpCas9	negative selection	7734574
6774676	6774699	12	-	27260156	PANC0327	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.18993612315400232	[264]	[144,215,169,287]	-3	hSpCas9	negative selection	7734575
6773868	6773891	12	-	27260156	PANC0327	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.3573483837160818	[172]	[170,111,101,99]	-5	hSpCas9	negative selection	7734576
6773295	6773318	12	-	27260156	PANC0327	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.16775394290684642	[834]	[820,566,528,748]	-2	hSpCas9	negative selection	7798831
6773919	6773942	12	+	27260156	PANC0327	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.14753201147678352	[203]	[43,222,228,140]	-2	hSpCas9	negative selection	7798832
6774652	6774675	12	-	27260156	PANC0327	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.9926296525863532	[159]	[35,146,42,46]	-8	hSpCas9	negative selection	7798833
6777784	6777807	12	+	27260156	NCIH2009	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.9674025034393945	[392]	[1365,1175,732]	9	hSpCas9	negative selection	7855825
6774676	6774699	12	-	27260156	NCIH2009	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.046787169400834716	[264]	[423,338,324]	0	hSpCas9	negative selection	7855826
6773868	6773891	12	-	27260156	NCIH2009	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.43368941347088796	[172]	[331,433,211]	6	hSpCas9	negative selection	7855827
6773295	6773318	12	-	27260156	NCIH2009	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.0964241174499374	[834]	[1223,925,1150]	-1	hSpCas9	negative selection	7920082
6773919	6773942	12	+	27260156	NCIH2009	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.40007018485657553	[203]	[416,179,90]	-5	hSpCas9	negative selection	7920083
6774652	6774675	12	-	27260156	NCIH2009	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.047659162082193784	[159]	[273,264,119]	0	hSpCas9	negative selection	7920084
6777784	6777807	12	+	27260156	NCIH1373	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.2052282473638097	[392]	[508,618,398,128]	2	hSpCas9	negative selection	7977076
6774676	6774699	12	-	27260156	NCIH1373	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.437610892880129	[264]	[221,249,919,46]	4	hSpCas9	negative selection	7977077
6773868	6773891	12	-	27260156	NCIH1373	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.5378576204684622	[172]	[148,208,69,25]	-5	hSpCas9	negative selection	7977078
6773295	6773318	12	-	27260156	NCIH1373	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.21788194616445644	[834]	[1555,1181,867,207]	2	hSpCas9	negative selection	8041333
6773919	6773942	12	+	27260156	NCIH1373	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.23160705703883577	[203]	[272,123,230,43]	-2	hSpCas9	negative selection	8041334
6774652	6774675	12	-	27260156	NCIH1373	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.07800705343257719	[159]	[192,161,171,61]	0	hSpCas9	negative selection	8041335
6777784	6777807	12	+	27260156	PATU8902	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.24910665697193496	[392]	[562,548,285,487]	-3	hSpCas9	negative selection	8098327
6774676	6774699	12	-	27260156	PATU8902	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.015436164355214	[264]	[592,264,200,484]	0	hSpCas9	negative selection	8098328
6773868	6773891	12	-	27260156	PATU8902	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.4214540507494149	[172]	[43,300,115,288]	-4	hSpCas9	negative selection	8098329
6773295	6773318	12	-	27260156	PATU8902	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-1.2153810118084871	[834]	[325,335,801,452]	-8	hSpCas9	negative selection	8162584
6773919	6773942	12	+	27260156	PATU8902	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.13441307456556828	[203]	[418,476,268,59]	1	hSpCas9	negative selection	8162585
6774652	6774675	12	-	27260156	PATU8902	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.270015525541901	[159]	[312,282,281,179]	2	hSpCas9	negative selection	8162586
6777784	6777807	12	+	27260156	PANC1	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.15352822311759828	[392]	[304,363,302,256]	-3	hSpCas9	negative selection	8219578
6774676	6774699	12	-	27260156	PANC1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.46367549182970874	[264]	[439,255,278,267]	7	hSpCas9	negative selection	8219579
6773868	6773891	12	-	27260156	PANC1	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.464988016920141	[172]	[230,179,180,216]	7	hSpCas9	negative selection	8219580
6773295	6773318	12	-	27260156	PANC1	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.12053740179855177	[834]	[744,908,782,707]	2	hSpCas9	negative selection	8283835
6773919	6773942	12	+	27260156	PANC1	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.22262567529727584	[203]	[199,234,236,156]	3	hSpCas9	negative selection	8283836
6774652	6774675	12	-	27260156	PANC1	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.17192236222609214	[159]	[134,133,77,137]	-3	hSpCas9	negative selection	8283837
6777784	6777807	12	+	27260156	PANC0813	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.7817957228248749	[392]	[986,668,825,713]	9	hSpCas9	negative selection	8340829
6774676	6774699	12	-	27260156	PANC0813	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.16056551127382201	[264]	[325,207,389,198]	-3	hSpCas9	negative selection	8340830
6773868	6773891	12	-	27260156	PANC0813	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.3058473442098397	[172]	[314,206,352,141]	5	hSpCas9	negative selection	8340831
6773295	6773318	12	-	27260156	PANC0813	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.10561078556822401	[834]	[1160,823,765,915]	-2	hSpCas9	negative selection	8405086
6773919	6773942	12	+	27260156	PANC0813	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.24048998936920263	[203]	[243,337,328,220]	4	hSpCas9	negative selection	8405087
6774652	6774675	12	-	27260156	PANC0813	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.31038771791150244	[159]	[163,126,177,138]	-5	hSpCas9	negative selection	8405088
6777784	6777807	12	+	27260156	RDES	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.19147979930298792	[392]	[460,542,423,644]	3	hSpCas9	negative selection	8462080
6774676	6774699	12	-	27260156	RDES	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.18893722869432628	[264]	[408,329,346,265]	3	hSpCas9	negative selection	8462081
6773868	6773891	12	-	27260156	RDES	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.39754360129199084	[172]	[84,188,157,183]	-6	hSpCas9	negative selection	8462082
6773295	6773318	12	-	27260156	RDES	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.5023968805303167	[834]	[485,654,840,774]	-7	hSpCas9	negative selection	8526337
6773919	6773942	12	+	27260156	RDES	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.07350898755225743	[203]	[186,155,389,279]	1	hSpCas9	negative selection	8526338
6774652	6774675	12	-	27260156	RDES	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.06793101729313644	[159]	[165,184,207,132]	-1	hSpCas9	negative selection	8526339
6777784	6777807	12	+	27260156	PC3	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	-0.11350622817856398	[392]	[227,351,588,392]	-3	hSpCas9	negative selection	8583331
6774676	6774699	12	-	27260156	PC3	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.35733027500079284	[264]	[284,161,500,465]	7	hSpCas9	negative selection	8583332
6773868	6773891	12	-	27260156	PC3	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.07149480638855055	[172]	[88,238,260,116]	-1	hSpCas9	negative selection	8583333
6773295	6773318	12	-	27260156	PC3	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.018534177452292244	[834]	[533,763,1161,1104]	0	hSpCas9	negative selection	8647588
6773919	6773942	12	+	27260156	PC3	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.14565884225342574	[203]	[122,282,359,206]	3	hSpCas9	negative selection	8647589
6774652	6774675	12	-	27260156	PC3	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.23644051634228824	[159]	[129,220,207,203]	5	hSpCas9	negative selection	8647590
6777784	6777807	12	+	27260156	PATU8988T	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.0009429770704698082	[392]	[308,619,346,256]	0	hSpCas9	negative selection	8704582
6774676	6774699	12	-	27260156	PATU8988T	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.19953800460216908	[264]	[396,227,217,330]	3	hSpCas9	negative selection	8704583
6773868	6773891	12	-	27260156	PATU8988T	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.5745499987226632	[172]	[435,319,155,77]	8	hSpCas9	negative selection	8704584
6773295	6773318	12	-	27260156	PATU8988T	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.32264549019772104	[834]	[790,1167,895,1213]	5	hSpCas9	negative selection	8768839
6773919	6773942	12	+	27260156	PATU8988T	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.8025510043227961	[203]	[113,118,93,126]	-8	hSpCas9	negative selection	8768840
6774652	6774675	12	-	27260156	PATU8988T	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.3825924703058412	[159]	[109,215,263,217]	6	hSpCas9	negative selection	8768841
6777784	6777807	12	+	27260156	T47D	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.05208276389117422	[392]	[491,381,543,487]	1	hSpCas9	negative selection	8825833
6774676	6774699	12	-	27260156	T47D	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.40060948867297547	[264]	[443,394,396,394]	8	hSpCas9	negative selection	8825834
6773868	6773891	12	-	27260156	T47D	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.01578505321189505	[172]	[178,180,253,201]	0	hSpCas9	negative selection	8825835
6773295	6773318	12	-	27260156	T47D	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.02178467417724117	[834]	[1084,864,901,990]	0	hSpCas9	negative selection	8890090
6773919	6773942	12	+	27260156	T47D	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.3965959739422906	[203]	[371,277,269,335]	8	hSpCas9	negative selection	8890091
6774652	6774675	12	-	27260156	T47D	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.1709068951316166	[159]	[232,214,168,222]	3	hSpCas9	negative selection	8890092
6777784	6777807	12	+	27260156	SU8686	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.5312469307903607	[392]	[454,578,677,546]	8	hSpCas9	negative selection	8947084
6774676	6774699	12	-	27260156	SU8686	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.03935265467629845	[264]	[267,218,145,482]	0	hSpCas9	negative selection	8947085
6773868	6773891	12	-	27260156	SU8686	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.373980238943435	[172]	[263,121,261,253]	6	hSpCas9	negative selection	8947086
6773295	6773318	12	-	27260156	SU8686	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.019472070672932218	[834]	[807,730,701,1177]	0	hSpCas9	negative selection	9011341
6773919	6773942	12	+	27260156	SU8686	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	-0.07157832721046398	[203]	[178,165,178,259]	-1	hSpCas9	negative selection	9011342
6774652	6774675	12	-	27260156	SU8686	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	-0.5301087490571625	[159]	[85,81,103,184]	-7	hSpCas9	negative selection	9011343
6777784	6777807	12	+	27260156	SKES1	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.06148713565760952	[392]	[451,394,435,358]	1	hSpCas9	negative selection	9068335
6774676	6774699	12	-	27260156	SKES1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.31388277312173807	[264]	[238,444,301,326]	6	hSpCas9	negative selection	9068336
6773868	6773891	12	-	27260156	SKES1	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.21933599527752046	[172]	[270,149,283,109]	5	hSpCas9	negative selection	9068337
6773295	6773318	12	-	27260156	SKES1	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.1949516769400368	[834]	[957,703,716,571]	-4	hSpCas9	negative selection	9132592
6773919	6773942	12	+	27260156	SKES1	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.17461001844624358	[203]	[330,231,244,133]	4	hSpCas9	negative selection	9132593
6774652	6774675	12	-	27260156	SKES1	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.09404965277792243	[159]	[176,192,219,100]	2	hSpCas9	negative selection	9132594
6777784	6777807	12	+	27260156	TOV112D	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.09568884449976967	[392]	[207,485,568,416]	1	hSpCas9	negative selection	9189586
6774676	6774699	12	-	27260156	TOV112D	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.5445333378662123	[264]	[385,270,505,356]	8	hSpCas9	negative selection	9189587
6773868	6773891	12	-	27260156	TOV112D	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	0.13133028010480507	[172]	[200,226,117,221]	2	hSpCas9	negative selection	9189588
6773295	6773318	12	-	27260156	TOV112D	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	-0.1849401579896095	[834]	[919,944,678,471]	-4	hSpCas9	negative selection	9253843
6773919	6773942	12	+	27260156	TOV112D	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.5699076426479935	[203]	[295,364,217,346]	8	hSpCas9	negative selection	9253844
6774652	6774675	12	-	27260156	TOV112D	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.30272439111435956	[159]	[355,161,119,157]	6	hSpCas9	negative selection	9253845
6777784	6777807	12	+	27260156	TC71	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.02374140903705746	[392]	[356,528,425,400]	0	hSpCas9	negative selection	9310837
6774676	6774699	12	-	27260156	TC71	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.34152221285043316	[264]	[334,349,494,248]	7	hSpCas9	negative selection	9310838
6773868	6773891	12	-	27260156	TC71	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.0729122932756252	[172]	[133,200,179,191]	-2	hSpCas9	negative selection	9310839
6773295	6773318	12	-	27260156	TC71	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.08006692607289556	[834]	[946,887,878,1080]	2	hSpCas9	negative selection	9375094
6773919	6773942	12	+	27260156	TC71	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.2304305781007322	[203]	[327,212,232,250]	5	hSpCas9	negative selection	9375095
6774652	6774675	12	-	27260156	TC71	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.14798755191555424	[159]	[226,164,144,225]	4	hSpCas9	negative selection	9375096
6777784	6777807	12	+	27260156	TC32	viability	TCCATAGGTGCCCAACGCTCTGG	LAG3	ENSG00000089692	0.16366831811625043	[392]	[404,228,699,418]	3	hSpCas9	negative selection	9432088
6774676	6774699	12	-	27260156	TC32	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.24803903070109035	[264]	[318,194,365,334]	4	hSpCas9	negative selection	9432089
6773868	6773891	12	-	27260156	TC32	viability	GCGAGAAGTCCCCGCGCTGCCGG	LAG3	ENSG00000089692	-0.03485605116212476	[172]	[125,110,177,240]	0	hSpCas9	negative selection	9432090
6773295	6773318	12	-	27260156	TC32	viability	TGACCCCTGCTCTTCGCAGAAGG	LAG3	ENSG00000089692	0.16636675452943994	[834]	[614,896,1014,996]	3	hSpCas9	negative selection	9496345
6773919	6773942	12	+	27260156	TC32	viability	CGCCGGCGAGTACCGCGCCGCGG	LAG3	ENSG00000089692	0.47172316478620047	[203]	[216,191,427,273]	7	hSpCas9	negative selection	9496346
6774652	6774675	12	-	27260156	TC32	viability	TGGGCGGTCAGGGCGGCTGAAGG	LAG3	ENSG00000089692	0.1354888824977165	[159]	[130,104,209,244]	2	hSpCas9	negative selection	9496347
6773843	6773866	12	-	27869803	HPAFII	viability after 27 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.6265580558631383	[572]	[703,265,NaN]	5	hSpCas9	negative selection	9548314
6774680	6774703	12	+	27869803	HPAFII	viability after 27 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	1.0142895458207757	[429]	[706,247,NaN]	8	hSpCas9	negative selection	9548315
6775412	6775435	12	-	27869803	HPAFII	viability after 27 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	-0.10446847456292155	[239]	[202,45,NaN]	-1	hSpCas9	negative selection	9548316
6777436	6777459	12	+	27869803	HPAFII	viability after 27 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.25904619683564445	[232]	[181,35,NaN]	-2	hSpCas9	negative selection	9548317
6777876	6777899	12	-	27869803	HPAFII	viability after 27 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.9194670081652623	[307]	[266,338,NaN]	7	hSpCas9	negative selection	9548318
6778273	6778296	12	+	27869803	HPAFII	viability after 27 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.498861192573716	[121]	[136,51,NaN]	4	hSpCas9	negative selection	9548319
6773843	6773866	12	-	27869803	HPAFII	viability after 15 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.032195607087710076	[572]	[912,408,NaN]	0	hSpCas9	negative selection	9630763
6774680	6774703	12	+	27869803	HPAFII	viability after 15 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	0.7797618699880864	[429]	[1282,488,NaN]	8	hSpCas9	negative selection	9630764
6775412	6775435	12	-	27869803	HPAFII	viability after 15 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.22604517596751714	[239]	[342,275,NaN]	2	hSpCas9	negative selection	9630765
6777436	6777459	12	+	27869803	HPAFII	viability after 15 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.08133218863639828	[232]	[452,147,NaN]	0	hSpCas9	negative selection	9630766
6777876	6777899	12	-	27869803	HPAFII	viability after 15 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.7710484508720485	[307]	[739,455,NaN]	8	hSpCas9	negative selection	9630767
6778273	6778296	12	+	27869803	HPAFII	viability after 15 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.13544347361715536	[121]	[209,102,NaN]	1	hSpCas9	negative selection	9630768
6773843	6773866	12	-	27869803	ASPC1	viability after 36 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.52116231837379	[1141]	[761,615,397]	5	hSpCas9	negative selection	9713212
6774680	6774703	12	+	27869803	ASPC1	viability after 36 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.39944386146832545	[1212]	[311,582,115]	-4	hSpCas9	negative selection	9713213
6775412	6775435	12	-	27869803	ASPC1	viability after 36 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.00014080032770352746	[830]	[410,365,141]	0	hSpCas9	negative selection	9713214
6777436	6777459	12	+	27869803	ASPC1	viability after 36 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.6349120363065943	[541]	[272,239,347]	6	hSpCas9	negative selection	9713215
6777876	6777899	12	-	27869803	ASPC1	viability after 36 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	1.2166712267758566	[742]	[489,440,803]	9	hSpCas9	negative selection	9713216
6778273	6778296	12	+	27869803	ASPC1	viability after 36 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.516372486331995	[311]	[87,298,87]	5	hSpCas9	negative selection	9713217
6773843	6773866	12	-	27869803	PATU8988S	viability after 35 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.1663059761720006	[1055]	[377,379,NaN]	-2	hSpCas9	negative selection	9795661
6774680	6774703	12	+	27869803	PATU8988S	viability after 35 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.26431943434998395	[1329]	[438,452,NaN]	-3	hSpCas9	negative selection	9795662
6775412	6775435	12	-	27869803	PATU8988S	viability after 35 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	-0.4061875366033849	[661]	[286,114,NaN]	-4	hSpCas9	negative selection	9795663
6777436	6777459	12	+	27869803	PATU8988S	viability after 35 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.2905067898797735	[538]	[172,181,NaN]	-3	hSpCas9	negative selection	9795664
6777876	6777899	12	-	27869803	PATU8988S	viability after 35 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.262756958930225	[913]	[507,374,NaN]	3	hSpCas9	negative selection	9795665
6778273	6778296	12	+	27869803	PATU8988S	viability after 35 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	-2.3205045061688625	[496]	[71,7,NaN]	-9	hSpCas9	negative selection	9795666
6773843	6773866	12	-	27869803	PATU8988S	viability after 31 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	-0.18883727890012703	[1055]	[236,537,NaN]	-2	hSpCas9	negative selection	9878110
6774680	6774703	12	+	27869803	PATU8988S	viability after 31 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	-0.30462133654476886	[1329]	[347,532,NaN]	-3	hSpCas9	negative selection	9878111
6775412	6775435	12	-	27869803	PATU8988S	viability after 31 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	0.0012391995712631165	[661]	[239,294,NaN]	0	hSpCas9	negative selection	9878112
6777436	6777459	12	+	27869803	PATU8988S	viability after 31 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.07292441369113312	[538]	[156,313,NaN]	0	hSpCas9	negative selection	9878113
6777876	6777899	12	-	27869803	PATU8988S	viability after 31 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	0.41637320934116984	[913]	[609,328,NaN]	5	hSpCas9	negative selection	9878114
6778273	6778296	12	+	27869803	PATU8988S	viability after 31 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	-2.265919498896017	[496]	[60,15,NaN]	-9	hSpCas9	negative selection	9878115
6773843	6773866	12	-	27869803	HPAFII	viability after 35 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	1.1297980504112957	[572]	[892,343,NaN]	7	hSpCas9	negative selection	9960559
6774680	6774703	12	+	27869803	HPAFII	viability after 35 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	1.1699632944913514	[429]	[692,260,NaN]	7	hSpCas9	negative selection	9960560
6775412	6775435	12	-	27869803	HPAFII	viability after 35 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	-0.31160586116174327	[239]	[127,63,NaN]	-2	hSpCas9	negative selection	9960561
6777436	6777459	12	+	27869803	HPAFII	viability after 35 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	-0.27030004826265075	[232]	[173,11,NaN]	-2	hSpCas9	negative selection	9960562
6777876	6777899	12	-	27869803	HPAFII	viability after 35 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	1.4151796102991319	[307]	[444,382,NaN]	8	hSpCas9	negative selection	9960563
6778273	6778296	12	+	27869803	HPAFII	viability after 35 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	0.5490847414770335	[121]	[119,56,NaN]	3	hSpCas9	negative selection	9960564
6773843	6773866	12	-	27869803	HPAFII	viability after 31 days	GCGCTCATCCAGCTGGACGCGGG	LAG3	ENSG00000089692	0.994034631259999	[572]	[874,384,NaN]	7	hSpCas9	negative selection	10043008
6774680	6774703	12	+	27869803	HPAFII	viability after 31 days	TGTGCATTGGTTCCGGAACCGGG	LAG3	ENSG00000089692	1.1874540434002763	[429]	[741,339,NaN]	8	hSpCas9	negative selection	10043009
6775412	6775435	12	-	27869803	HPAFII	viability after 31 days	CGCCATTGTCTCCAGTCACCAGG	LAG3	ENSG00000089692	-0.2205218083199442	[239]	[128,100,NaN]	-1	hSpCas9	negative selection	10043010
6777436	6777459	12	+	27869803	HPAFII	viability after 31 days	GCAATGCCAGCTGTACCAGGGGG	LAG3	ENSG00000089692	0.018255661588904126	[232]	[208,48,NaN]	0	hSpCas9	negative selection	10043011
6777876	6777899	12	-	27869803	HPAFII	viability after 31 days	CAAAGGCTCCAGTCACCAAAAGG	LAG3	ENSG00000089692	1.0632387415738522	[307]	[320,404,NaN]	7	hSpCas9	negative selection	10043012
6778273	6778296	12	+	27869803	HPAFII	viability after 31 days	GCAAGGGATTCACCCTCCGCAGG	LAG3	ENSG00000089692	-0.13174674208118553	[121]	[39,86,NaN]	-1	hSpCas9	negative selection	10043013
6772870	6772893	12	-	28162770	P31FUJ	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.49098800100409434	[197]	[326]	5	hSpCas9	negative selection	10182732
6775340	6775363	12	-	28162770	P31FUJ	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.4428196094653702	[220]	[352]	5	hSpCas9	negative selection	10182733
6773280	6773303	12	-	28162770	P31FUJ	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-0.5650722435232001	[174]	[138]	-5	hSpCas9	negative selection	10182734
6773791	6773814	12	+	28162770	P31FUJ	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.4895340871272702	[336]	[555]	5	hSpCas9	negative selection	10182735
6773936	6773959	12	-	28162770	P31FUJ	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.4676375137267136	[311]	[506]	5	hSpCas9	negative selection	10182736
6774607	6774630	12	-	28162770	P31FUJ	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	0.2595110083411028	[208]	[293]	3	hSpCas9	negative selection	10182737
6777834	6777857	12	-	28162770	P31FUJ	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-1.0919396685745288	[155]	[85]	-6	hSpCas9	negative selection	10182738
6777855	6777878	12	-	28162770	P31FUJ	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.2666610084304146	[387]	[378]	-3	hSpCas9	negative selection	10182739
6774676	6774699	12	-	28162770	P31FUJ	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.8772513410505351	[245]	[530]	8	hSpCas9	negative selection	10182740
6774795	6774818	12	-	28162770	P31FUJ	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.2160589405798024	[256]	[259]	-2	hSpCas9	negative selection	10182741
6772870	6772893	12	-	28162770	TF1	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	NaN	[NaN]	[139]	1	hSpCas9	negative selection	10352098
6775340	6775363	12	-	28162770	TF1	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	NaN	[NaN]	[267]	1	hSpCas9	negative selection	10352099
6773280	6773303	12	-	28162770	TF1	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	NaN	[NaN]	[177]	1	hSpCas9	negative selection	10352100
6773791	6773814	12	+	28162770	TF1	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	NaN	[NaN]	[248]	1	hSpCas9	negative selection	10352101
6773936	6773959	12	-	28162770	TF1	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	NaN	[NaN]	[209]	1	hSpCas9	negative selection	10352102
6774607	6774630	12	-	28162770	TF1	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	NaN	[NaN]	[65]	1	hSpCas9	negative selection	10352103
6777834	6777857	12	-	28162770	TF1	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	NaN	[NaN]	[96]	1	hSpCas9	negative selection	10352104
6777855	6777878	12	-	28162770	TF1	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	NaN	[NaN]	[201]	1	hSpCas9	negative selection	10352105
6774676	6774699	12	-	28162770	TF1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	NaN	[NaN]	[217]	1	hSpCas9	negative selection	10352106
6774795	6774818	12	-	28162770	TF1	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	NaN	[NaN]	[140]	1	hSpCas9	negative selection	10352107
6772870	6772893	12	-	28162770	SKM1	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.3287782541536035	[58]	[130]	3	hSpCas9	negative selection	10521464
6775340	6775363	12	-	28162770	SKM1	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.4697644263551042	[57]	[141]	4	hSpCas9	negative selection	10521465
6773280	6773303	12	-	28162770	SKM1	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.11480447549080053	[34]	[66]	1	hSpCas9	negative selection	10521466
6773791	6773814	12	+	28162770	SKM1	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	-0.2661855429603659	[99]	[146]	-2	hSpCas9	negative selection	10521467
6773936	6773959	12	-	28162770	SKM1	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.4154385263949463	[108]	[256]	4	hSpCas9	negative selection	10521468
6774607	6774630	12	-	28162770	SKM1	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.871754733219105	[58]	[56]	-6	hSpCas9	negative selection	10521469
6777834	6777857	12	-	28162770	SKM1	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	0.6474835852792147	[38]	[107]	6	hSpCas9	negative selection	10521470
6777855	6777878	12	-	28162770	SKM1	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.5324950808270206	[98]	[120]	-4	hSpCas9	negative selection	10521471
6774676	6774699	12	-	28162770	SKM1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.9014361655164104	[55]	[52]	-6	hSpCas9	negative selection	10521472
6774795	6774818	12	-	28162770	SKM1	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.7130673264688414	[50]	[54]	-5	hSpCas9	negative selection	10521473
6772870	6772893	12	-	28162770	SKM1	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.3287782541536035	[58]	[130]	3	hSpCas9	negative selection	10690830
6775340	6775363	12	-	28162770	SKM1	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.4697644263551042	[57]	[141]	4	hSpCas9	negative selection	10690831
6773280	6773303	12	-	28162770	SKM1	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.11480447549080053	[34]	[66]	1	hSpCas9	negative selection	10690832
6773791	6773814	12	+	28162770	SKM1	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	-0.2661855429603659	[99]	[146]	-2	hSpCas9	negative selection	10690833
6773936	6773959	12	-	28162770	SKM1	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.4154385263949463	[108]	[256]	4	hSpCas9	negative selection	10690834
6774607	6774630	12	-	28162770	SKM1	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.871754733219105	[58]	[56]	-6	hSpCas9	negative selection	10690835
6777834	6777857	12	-	28162770	SKM1	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	0.6474835852792147	[38]	[107]	6	hSpCas9	negative selection	10690836
6777855	6777878	12	-	28162770	SKM1	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.5324950808270206	[98]	[120]	-4	hSpCas9	negative selection	10690837
6774676	6774699	12	-	28162770	SKM1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.9014361655164104	[55]	[52]	-6	hSpCas9	negative selection	10690838
6774795	6774818	12	-	28162770	SKM1	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.7130673264688414	[50]	[54]	-5	hSpCas9	negative selection	10690839
6772870	6772893	12	-	28162770	PL21	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.06263609073938514	[219]	[99]	0	hSpCas9	negative selection	10860196
6775340	6775363	12	-	28162770	PL21	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	-0.7301514136992754	[201]	[52]	-5	hSpCas9	negative selection	10860197
6773280	6773303	12	-	28162770	PL21	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-1.790337611392173	[150]	[18]	-8	hSpCas9	negative selection	10860198
6773791	6773814	12	+	28162770	PL21	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	-0.5873655317092625	[396]	[114]	-4	hSpCas9	negative selection	10860199
6773936	6773959	12	-	28162770	PL21	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.6515189608318843	[293]	[200]	5	hSpCas9	negative selection	10860200
6774607	6774630	12	-	28162770	PL21	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	0.8033412334955188	[261]	[198]	7	hSpCas9	negative selection	10860201
6777834	6777857	12	-	28162770	PL21	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-4.057248228203332	[152]	[3]	-9	hSpCas9	negative selection	10860202
6777855	6777878	12	-	28162770	PL21	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.9271792155751324	[366]	[83]	-6	hSpCas9	negative selection	10860203
6774676	6774699	12	-	28162770	PL21	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.8280572773413319	[154]	[37]	-5	hSpCas9	negative selection	10860204
6774795	6774818	12	-	28162770	PL21	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	1.0488960341130826	[210]	[189]	8	hSpCas9	negative selection	10860205
6772870	6772893	12	-	28162770	P31FUJ	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.49098800100409434	[197]	[326]	5	hSpCas9	negative selection	11029562
6775340	6775363	12	-	28162770	P31FUJ	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.4428196094653702	[220]	[352]	5	hSpCas9	negative selection	11029563
6773280	6773303	12	-	28162770	P31FUJ	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-0.5650722435232001	[174]	[138]	-5	hSpCas9	negative selection	11029564
6773791	6773814	12	+	28162770	P31FUJ	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.4895340871272702	[336]	[555]	5	hSpCas9	negative selection	11029565
6773936	6773959	12	-	28162770	P31FUJ	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.4676375137267136	[311]	[506]	5	hSpCas9	negative selection	11029566
6774607	6774630	12	-	28162770	P31FUJ	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	0.2595110083411028	[208]	[293]	3	hSpCas9	negative selection	11029567
6777834	6777857	12	-	28162770	P31FUJ	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-1.0919396685745288	[155]	[85]	-6	hSpCas9	negative selection	11029568
6777855	6777878	12	-	28162770	P31FUJ	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.2666610084304146	[387]	[378]	-3	hSpCas9	negative selection	11029569
6774676	6774699	12	-	28162770	P31FUJ	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.8772513410505351	[245]	[530]	8	hSpCas9	negative selection	11029570
6774795	6774818	12	-	28162770	P31FUJ	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.2160589405798024	[256]	[259]	-2	hSpCas9	negative selection	11029571
6772870	6772893	12	-	28162770	OCIAML5	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.6477793162192085	[63]	[180]	5	hSpCas9	negative selection	11198928
6775340	6775363	12	-	28162770	OCIAML5	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.8084469628643358	[123]	[391]	7	hSpCas9	negative selection	11198929
6773280	6773303	12	-	28162770	OCIAML5	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-0.011544784871193425	[85]	[153]	0	hSpCas9	negative selection	11198930
6773791	6773814	12	+	28162770	OCIAML5	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	-0.5274937547210707	[217]	[272]	-4	hSpCas9	negative selection	11198931
6773936	6773959	12	-	28162770	OCIAML5	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.3448254781785847	[105]	[242]	3	hSpCas9	negative selection	11198932
6774607	6774630	12	-	28162770	OCIAML5	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.12215573423174131	[163]	[271]	-1	hSpCas9	negative selection	11198933
6777834	6777857	12	-	28162770	OCIAML5	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-3.5647846187835257	[117]	[17]	-9	hSpCas9	negative selection	11198934
6777855	6777878	12	-	28162770	OCIAML5	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.8706025223014247	[234]	[231]	-5	hSpCas9	negative selection	11198935
6774676	6774699	12	-	28162770	OCIAML5	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.5421111176427106	[120]	[149]	-4	hSpCas9	negative selection	11198936
6774795	6774818	12	-	28162770	OCIAML5	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	0.4329764559035565	[102]	[250]	4	hSpCas9	negative selection	11198937
6772870	6772893	12	-	28162770	EOL1	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.5329291596753278	[386]	[294]	5	hSpCas9	negative selection	11368294
6775340	6775363	12	-	28162770	EOL1	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.4792372611778901	[304]	[223]	4	hSpCas9	negative selection	11368295
6773280	6773303	12	-	28162770	EOL1	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-1.4508195822782881	[274]	[52]	-7	hSpCas9	negative selection	11368296
6773791	6773814	12	+	28162770	EOL1	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.20908945056778805	[687]	[418]	2	hSpCas9	negative selection	11368297
6773936	6773959	12	-	28162770	EOL1	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	-0.14508641626651775	[572]	[272]	-1	hSpCas9	negative selection	11368298
6774607	6774630	12	-	28162770	EOL1	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.3310378284881318	[424]	[177]	-2	hSpCas9	negative selection	11368299
6777834	6777857	12	-	28162770	EOL1	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-3.8379529147028095	[189]	[6]	-9	hSpCas9	negative selection	11368300
6777855	6777878	12	-	28162770	EOL1	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.9083422425942071	[512]	[143]	-6	hSpCas9	negative selection	11368301
6774676	6774699	12	-	28162770	EOL1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.13187274481804084	[219]	[126]	1	hSpCas9	negative selection	11368302
6774795	6774818	12	-	28162770	EOL1	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	0.7154521728475444	[251]	[217]	6	hSpCas9	negative selection	11368303
6772870	6772893	12	-	28162770	MOLM13	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.3766213239772647	[260]	[244]	2	hSpCas9	negative selection	11537660
6775340	6775363	12	-	28162770	MOLM13	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	1.4989162771652034	[275]	[563]	9	hSpCas9	negative selection	11537661
6773280	6773303	12	-	28162770	MOLM13	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.17838276434959405	[219]	[179]	1	hSpCas9	negative selection	11537662
6773791	6773814	12	+	28162770	MOLM13	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.5790429614058216	[436]	[471]	4	hSpCas9	negative selection	11537663
6773936	6773959	12	-	28162770	MOLM13	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.9792844218033265	[408]	[582]	7	hSpCas9	negative selection	11537664
6774607	6774630	12	-	28162770	MOLM13	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.5014138212325046	[371]	[189]	-3	hSpCas9	negative selection	11537665
6777834	6777857	12	-	28162770	MOLM13	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-5.898432832701237	[164]	[1]	-9	hSpCas9	negative selection	11537666
6777855	6777878	12	-	28162770	MOLM13	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-3.172114482734539	[560]	[44]	-8	hSpCas9	negative selection	11537667
6774676	6774699	12	-	28162770	MOLM13	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.451113668793752	[345]	[341]	3	hSpCas9	negative selection	11537668
6774795	6774818	12	-	28162770	MOLM13	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.005626582999994301	[192]	[138]	0	hSpCas9	negative selection	11537669
6772870	6772893	12	-	28162770	HEL	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.6014318578434436	[247]	[240]	5	hSpCas9	negative selection	11707026
6775340	6775363	12	-	28162770	HEL	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	-0.20820535860492995	[293]	[162]	-1	hSpCas9	negative selection	11707027
6773280	6773303	12	-	28162770	HEL	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.8032035041936031	[203]	[227]	7	hSpCas9	negative selection	11707028
6773791	6773814	12	+	28162770	HEL	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.27676215117239944	[423]	[328]	2	hSpCas9	negative selection	11707029
6773936	6773959	12	-	28162770	HEL	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.8908999613526205	[324]	[385]	7	hSpCas9	negative selection	11707030
6774607	6774630	12	-	28162770	HEL	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.22119961842361444	[272]	[149]	-1	hSpCas9	negative selection	11707031
6777834	6777857	12	-	28162770	HEL	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-1.931731294903157	[136]	[22]	-7	hSpCas9	negative selection	11707032
6777855	6777878	12	-	28162770	HEL	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-1.88347108143671	[408]	[70]	-7	hSpCas9	negative selection	11707033
6774676	6774699	12	-	28162770	HEL	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	-0.9110627372343387	[228]	[77]	-5	hSpCas9	negative selection	11707034
6774795	6774818	12	-	28162770	HEL	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-1.6187534090250315	[186]	[38]	-7	hSpCas9	negative selection	11707035
6772870	6772893	12	-	28162770	MV411	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.37401804734791827	[228]	[249]	3	hSpCas9	negative selection	11876392
6775340	6775363	12	-	28162770	MV411	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	-0.031026895620624637	[187]	[154]	0	hSpCas9	negative selection	11876393
6773280	6773303	12	-	28162770	MV411	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	0.04245581299514681	[150]	[130]	0	hSpCas9	negative selection	11876394
6773791	6773814	12	+	28162770	MV411	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.3506677078914313	[363]	[390]	3	hSpCas9	negative selection	11876395
6773936	6773959	12	-	28162770	MV411	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	-0.21618012894113026	[301]	[218]	-2	hSpCas9	negative selection	11876396
6774607	6774630	12	-	28162770	MV411	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.8148467274715672	[212]	[101]	-5	hSpCas9	negative selection	11876397
6777834	6777857	12	-	28162770	MV411	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-3.803188522287193	[115]	[6]	-9	hSpCas9	negative selection	11876398
6777855	6777878	12	-	28162770	MV411	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.9012397169554978	[336]	[151]	-6	hSpCas9	negative selection	11876399
6774676	6774699	12	-	28162770	MV411	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.3365210943652005	[156]	[166]	3	hSpCas9	negative selection	11876400
6774795	6774818	12	-	28162770	MV411	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.40563997486299286	[205]	[130]	-3	hSpCas9	negative selection	11876401
6772870	6772893	12	-	28162770	MONOMAC1	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	0.5504211209242947	[136]	[229]	5	hSpCas9	negative selection	12045758
6775340	6775363	12	-	28162770	MONOMAC1	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.6302864912306465	[163]	[290]	6	hSpCas9	negative selection	12045759
6773280	6773303	12	-	28162770	MONOMAC1	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-0.24189108284381405	[97]	[94]	-2	hSpCas9	negative selection	12045760
6773791	6773814	12	+	28162770	MONOMAC1	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	-0.06301949908786608	[225]	[247]	0	hSpCas9	negative selection	12045761
6773936	6773959	12	-	28162770	MONOMAC1	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.2677536874163898	[170]	[235]	2	hSpCas9	negative selection	12045762
6774607	6774630	12	-	28162770	MONOMAC1	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.29544055112054834	[181]	[169]	-3	hSpCas9	negative selection	12045763
6777834	6777857	12	-	28162770	MONOMAC1	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-0.7819993477807098	[89]	[59]	-6	hSpCas9	negative selection	12045764
6777855	6777878	12	-	28162770	MONOMAC1	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-0.6951560878329526	[273]	[193]	-5	hSpCas9	negative selection	12045765
6774676	6774699	12	-	28162770	MONOMAC1	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.3175363257702045	[90]	[129]	3	hSpCas9	negative selection	12045766
6774795	6774818	12	-	28162770	MONOMAC1	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	0.2899504940983049	[131]	[184]	3	hSpCas9	negative selection	12045767
6772870	6772893	12	-	28162770	OCIAML2	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	-0.023170848270939903	[43]	[239]	0	hSpCas9	negative selection	12215124
6775340	6775363	12	-	28162770	OCIAML2	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	0.5164311190503406	[41]	[332]	5	hSpCas9	negative selection	12215125
6773280	6773303	12	-	28162770	OCIAML2	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-0.8599042284559232	[36]	[112]	-6	hSpCas9	negative selection	12215126
6773791	6773814	12	+	28162770	OCIAML2	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.14290182767576587	[49]	[305]	1	hSpCas9	negative selection	12215127
6773936	6773959	12	-	28162770	OCIAML2	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	0.8623534581541971	[51]	[523]	8	hSpCas9	negative selection	12215128
6774607	6774630	12	-	28162770	OCIAML2	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.3926273132408883	[44]	[189]	-3	hSpCas9	negative selection	12215129
6777834	6777857	12	-	28162770	OCIAML2	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-3.083606702132914	[25]	[16]	-9	hSpCas9	negative selection	12215130
6777855	6777878	12	-	28162770	OCIAML2	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	-1.9815917445195406	[56]	[79]	-8	hSpCas9	negative selection	12215131
6774676	6774699	12	-	28162770	OCIAML2	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.31072988828249837	[31]	[219]	3	hSpCas9	negative selection	12215132
6774795	6774818	12	-	28162770	OCIAML2	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	0.23771509098427704	[27]	[182]	2	hSpCas9	negative selection	12215133
6772870	6772893	12	-	28162770	OCIAML3	viability	GCTGCAGAAACAGCAAGCCCAGG	LAG3	ENSG00000089692	-0.09150729979498001	[47]	[135]	0	hSpCas9	negative selection	12384490
6775340	6775363	12	-	28162770	OCIAML3	viability	GGGTCCCCACACCAGCAGGCAGG	LAG3	ENSG00000089692	-0.3086054214619148	[63]	[155]	-2	hSpCas9	negative selection	12384491
6773280	6773303	12	-	28162770	OCIAML3	viability	GCAGAAGGCTGAGATCCTGGAGG	LAG3	ENSG00000089692	-1.1465486633529418	[32]	[44]	-7	hSpCas9	negative selection	12384492
6773791	6773814	12	+	28162770	OCIAML3	viability	GTGCTGAGCGTGGGTCCCGGAGG	LAG3	ENSG00000089692	0.18018041779824168	[87]	[300]	1	hSpCas9	negative selection	12384493
6773936	6773959	12	-	28162770	OCIAML3	viability	GCGGTCCCTGAGGTGCACCGCGG	LAG3	ENSG00000089692	-0.5940076403241631	[102]	[205]	-4	hSpCas9	negative selection	12384494
6774607	6774630	12	-	28162770	OCIAML3	viability	GGAGGCTCTGAGAGATCCTGGGG	LAG3	ENSG00000089692	-0.6261880460733129	[67]	[132]	-5	hSpCas9	negative selection	12384495
6777834	6777857	12	-	28162770	OCIAML3	viability	GGATGAGAAACAGCAGGAGGTGG	LAG3	ENSG00000089692	-2.108580813153921	[29]	[20]	-8	hSpCas9	negative selection	12384496
6777855	6777878	12	-	28162770	OCIAML3	viability	GGAGCAGAGAAAGGACACCAAGG	LAG3	ENSG00000089692	0.2627594758585189	[81]	[296]	2	hSpCas9	negative selection	12384497
6774676	6774699	12	-	28162770	OCIAML3	viability	GTTCCGGAACCAATGCACAGAGG	LAG3	ENSG00000089692	0.8378381466412343	[47]	[258]	7	hSpCas9	negative selection	12384498
6774795	6774818	12	-	28162770	OCIAML3	viability	TAGGTGAGGATGCAGCCCCAGGG	LAG3	ENSG00000089692	-0.5940076403241632	[54]	[109]	-4	hSpCas9	negative selection	12384499