Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3909
• Symbol:LAMA3
• Description:laminin subunit alpha 3

DataSource: http://genomecrispr.dkfz.de/#!/results/LAMA3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
23881935	23881958	18	+	26472758	Jiyoye	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	1.335025595750038	[40]	[77]	7	hSpCas9	negative selection	88640
23904551	23904574	18	+	26472758	Jiyoye	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.5434968527186536	[110]	[121]	4	hSpCas9	negative selection	88641
23904606	23904629	18	-	26472758	Jiyoye	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.8334401362079714	[127]	[171]	6	hSpCas9	negative selection	88642
23916641	23916664	18	+	26472758	Jiyoye	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.8743013919331716	[33]	[46]	6	hSpCas9	negative selection	88643
23882004	23882027	18	-	26472758	Jiyoye	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.3518165189903317	[219]	[129]	-3	hSpCas9	negative selection	88644
23894965	23894988	18	-	26472758	Jiyoye	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	1.1914466904504364	[17]	[30]	7	hSpCas9	negative selection	88645
23895028	23895051	18	+	26472758	Jiyoye	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	1.081111512049306	[130]	[208]	7	hSpCas9	negative selection	88646
23903061	23903084	18	-	26472758	Jiyoye	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	-0.13618621474850978	[187]	[128]	-1	hSpCas9	negative selection	88647
23904013	23904036	18	+	26472758	Jiyoye	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.7127344039862241	[194]	[240]	5	hSpCas9	negative selection	88648
23904033	23904056	18	+	26472758	Jiyoye	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	1.7442103687834438	[18]	[47]	8	hSpCas9	negative selection	88649
23881935	23881958	18	+	26472758	KBM7	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.9597108217589676	[429,288]	[535,133]	9	hSpCas9	negative selection	279758
23904551	23904574	18	+	26472758	KBM7	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.4752995077388884	[526,275]	[267,243]	5	hSpCas9	negative selection	279759
23904606	23904629	18	-	26472758	KBM7	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.029871770601305248	[842,476]	[358,264]	0	hSpCas9	negative selection	279760
23916641	23916664	18	+	26472758	KBM7	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.47282476091175285	[73,59]	[62,25]	5	hSpCas9	negative selection	279761
23882004	23882027	18	-	26472758	KBM7	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.25911149064122324	[696,553]	[270,219]	-2	hSpCas9	negative selection	279762
23894965	23894988	18	-	26472758	KBM7	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	0.45779696079002496	[197,94]	[97,85]	5	hSpCas9	negative selection	279763
23895028	23895051	18	+	26472758	KBM7	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.5840126005818191	[776,481]	[402,463]	6	hSpCas9	negative selection	279764
23903061	23903084	18	-	26472758	KBM7	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.21929474798228032	[508,468]	[147,374]	2	hSpCas9	negative selection	279765
23904013	23904036	18	+	26472758	KBM7	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.040054482136600456	[740,707]	[461,251]	0	hSpCas9	negative selection	279766
23904033	23904056	18	+	26472758	KBM7	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.42323623699539703	[178,47]	[16,112]	4	hSpCas9	negative selection	279767
23881935	23881958	18	+	26472758	Raji	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.2952435507506186	[150]	[42]	3	hSpCas9	negative selection	470876
23904551	23904574	18	+	26472758	Raji	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.036994207482201585	[209]	[49]	0	hSpCas9	negative selection	470877
23904606	23904629	18	-	26472758	Raji	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.17728554860375584	[281]	[73]	1	hSpCas9	negative selection	470878
23916641	23916664	18	+	26472758	Raji	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	1.3418487890106223	[16]	[9]	9	hSpCas9	negative selection	470879
23882004	23882027	18	-	26472758	Raji	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	0.5061192223233428	[266]	[87]	5	hSpCas9	negative selection	470880
23894965	23894988	18	-	26472758	Raji	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	0.7318744002813931	[95]	[36]	6	hSpCas9	negative selection	470881
23895028	23895051	18	+	26472758	Raji	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.24013874422537101	[331]	[90]	2	hSpCas9	negative selection	470882
23903061	23903084	18	-	26472758	Raji	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	1.094783498593966	[229]	[113]	8	hSpCas9	negative selection	470883
23904013	23904036	18	+	26472758	Raji	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	1.0597655151408598	[307]	[148]	8	hSpCas9	negative selection	470884
23904033	23904056	18	+	26472758	Raji	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-3.3188812193284987	[42]	[0]	-9	hSpCas9	negative selection	470885
23881935	23881958	18	+	26472758	K562	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.5221505795446573	[278]	[163]	-3	hSpCas9	negative selection	661994
23904551	23904574	18	+	26472758	K562	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.31748218985617016	[307]	[323]	2	hSpCas9	negative selection	661995
23904606	23904629	18	-	26472758	K562	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	-0.44891993409950137	[607]	[375]	-3	hSpCas9	negative selection	661996
23916641	23916664	18	+	26472758	K562	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.28289287548108266	[36]	[37]	2	hSpCas9	negative selection	661997
23882004	23882027	18	-	26472758	K562	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.899971181668728	[629]	[284]	-5	hSpCas9	negative selection	661998
23894965	23894988	18	-	26472758	K562	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	-0.08640576770931174	[121]	[96]	0	hSpCas9	negative selection	661999
23895028	23895051	18	+	26472758	K562	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.29985111847734863	[433]	[450]	2	hSpCas9	negative selection	662000
23903061	23903084	18	-	26472758	K562	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	-0.8100290563559294	[377]	[181]	-5	hSpCas9	negative selection	662001
23904013	23904036	18	+	26472758	K562	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.028854862672185067	[706]	[584]	0	hSpCas9	negative selection	662002
23904033	23904056	18	+	26472758	K562	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.1319439984080346	[39]	[36]	1	hSpCas9	negative selection	662003
23689842	23689865	18	-	26627737	DLD1	viability	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-0.6849374630108693	[192]	[51,51,12]	-6	hSpCas9	negative selection	801213
23748025	23748048	18	+	26627737	DLD1	viability	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.0022792375728217795	[1147]	[314,444,323]	0	hSpCas9	negative selection	801214
23749465	23749488	18	+	26627737	DLD1	viability	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.5592264435246307	[286]	[140,185,79]	5	hSpCas9	negative selection	801215
23750974	23750997	18	+	26627737	DLD1	viability	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.35247840754400384	[921]	[223,347,125]	-4	hSpCas9	negative selection	801216
23758392	23758415	18	-	26627737	DLD1	viability	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.5944349997658096	[1749]	[706,918,851]	6	hSpCas9	negative selection	801217
23763463	23763486	18	+	26627737	DLD1	viability	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.7396585026648049	[390]	[261,273,95]	7	hSpCas9	negative selection	801218
23689842	23689865	18	-	26627737	GBM cells	viability after 5 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.22387602986268118	[94]	[25,92]	3	hSpCas9	negative selection	883528
23748025	23748048	18	+	26627737	GBM cells	viability after 5 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.07162885020250553	[573]	[304,341]	1	hSpCas9	negative selection	883529
23749465	23749488	18	+	26627737	GBM cells	viability after 5 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.640720732121391	[118]	[75,122]	8	hSpCas9	negative selection	883530
23750974	23750997	18	+	26627737	GBM cells	viability after 5 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.34385070196982426	[522]	[159,281]	-5	hSpCas9	negative selection	883531
23758392	23758415	18	-	26627737	GBM cells	viability after 5 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.16650504716701597	[1000]	[679,524]	2	hSpCas9	negative selection	883532
23763463	23763486	18	+	26627737	GBM cells	viability after 5 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.3267754145221131	[167]	[116,108]	5	hSpCas9	negative selection	883533
23689842	23689865	18	-	26627737	GBM cells	viability after 13 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.7548251698261329	[94]	[38,125]	8	hSpCas9	negative selection	965843
23748025	23748048	18	+	26627737	GBM cells	viability after 13 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.15485648792104634	[573]	[429,278]	2	hSpCas9	negative selection	965844
23749465	23749488	18	+	26627737	GBM cells	viability after 13 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.8638925853024704	[118]	[95,134]	8	hSpCas9	negative selection	965845
23750974	23750997	18	+	26627737	GBM cells	viability after 13 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.531312640996254	[522]	[272,133]	-6	hSpCas9	negative selection	965846
23758392	23758415	18	-	26627737	GBM cells	viability after 13 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.2742550147175873	[1000]	[738,589]	3	hSpCas9	negative selection	965847
23763463	23763486	18	+	26627737	GBM cells	viability after 13 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-0.010016806841174897	[167]	[100,81]	0	hSpCas9	negative selection	965848
23689842	23689865	18	-	26627737	GBM cells	viability after 21 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	1.1073906691208555	[94]	[129,93]	9	hSpCas9	negative selection	1048158
23748025	23748048	18	+	26627737	GBM cells	viability after 21 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.24612038629063637	[573]	[287,239]	-2	hSpCas9	negative selection	1048159
23749465	23749488	18	+	26627737	GBM cells	viability after 21 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.6485387306037789	[118]	[104,97]	6	hSpCas9	negative selection	1048160
23750974	23750997	18	+	26627737	GBM cells	viability after 21 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-1.2168087453156298	[522]	[139,105]	-7	hSpCas9	negative selection	1048161
23758392	23758415	18	-	26627737	GBM cells	viability after 21 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.26318502876126093	[1000]	[695,612]	2	hSpCas9	negative selection	1048162
23763463	23763486	18	+	26627737	GBM cells	viability after 21 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-0.004994268049691719	[167]	[91,89]	0	hSpCas9	negative selection	1048163
23689842	23689865	18	-	26627737	RPE1	viability after 9 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-0.6674983179878533	[372]	[52,99]	-5	hSpCas9	negative selection	1130473
23748025	23748048	18	+	26627737	RPE1	viability after 9 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.0027537605602661053	[1704]	[529,540]	0	hSpCas9	negative selection	1130474
23749465	23749488	18	+	26627737	RPE1	viability after 9 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.22439040747543898	[507]	[242,111]	1	hSpCas9	negative selection	1130475
23750974	23750997	18	+	26627737	RPE1	viability after 9 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.7753843950451256	[1208]	[639,657]	5	hSpCas9	negative selection	1130476
23758392	23758415	18	-	26627737	RPE1	viability after 9 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.27366143633631523	[3982]	[1120,2005]	2	hSpCas9	negative selection	1130477
23763463	23763486	18	+	26627737	RPE1	viability after 9 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.8643472679366053	[666]	[363,400]	5	hSpCas9	negative selection	1130478
23689842	23689865	18	-	26627737	RPE1	viability after 12 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-0.8322235111833278	[372]	[14,99]	-5	hSpCas9	negative selection	1212788
23748025	23748048	18	+	26627737	RPE1	viability after 12 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.1699441529817407	[1704]	[475,556]	1	hSpCas9	negative selection	1212789
23749465	23749488	18	+	26627737	RPE1	viability after 12 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.017590835907151492	[507]	[213,50]	0	hSpCas9	negative selection	1212790
23750974	23750997	18	+	26627737	RPE1	viability after 12 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.7054278500640281	[1208]	[483,577]	4	hSpCas9	negative selection	1212791
23758392	23758415	18	-	26627737	RPE1	viability after 12 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.32857436735037293	[3982]	[1132,1566]	2	hSpCas9	negative selection	1212792
23763463	23763486	18	+	26627737	RPE1	viability after 12 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.7785418152919619	[666]	[337,274]	5	hSpCas9	negative selection	1212793
23689842	23689865	18	-	26627737	RPE1	viability after 15 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-0.0425354461836136	[372]	[20,180]	0	hSpCas9	negative selection	1295103
23748025	23748048	18	+	26627737	RPE1	viability after 15 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.0011325890879916312	[1704]	[415,546]	0	hSpCas9	negative selection	1295104
23749465	23749488	18	+	26627737	RPE1	viability after 15 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.8597691262791447	[507]	[497,31]	5	hSpCas9	negative selection	1295105
23750974	23750997	18	+	26627737	RPE1	viability after 15 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.6866898051262196	[1208]	[607,494]	4	hSpCas9	negative selection	1295106
23758392	23758415	18	-	26627737	RPE1	viability after 15 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.4046748790296464	[3982]	[1377,1600]	2	hSpCas9	negative selection	1295107
23763463	23763486	18	+	26627737	RPE1	viability after 15 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.8059048720089875	[666]	[365,294]	5	hSpCas9	negative selection	1295108
23689842	23689865	18	-	26627737	RPE1	viability after 18 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-0.33889038451064146	[372]	[52,107]	-2	hSpCas9	negative selection	1377418
23748025	23748048	18	+	26627737	RPE1	viability after 18 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.19016630076836738	[1704]	[382,424]	-1	hSpCas9	negative selection	1377419
23749465	23749488	18	+	26627737	RPE1	viability after 18 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.10061983702528321	[507]	[181,69]	0	hSpCas9	negative selection	1377420
23750974	23750997	18	+	26627737	RPE1	viability after 18 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.8189022312641796	[1208]	[489,666]	5	hSpCas9	negative selection	1377421
23758392	23758415	18	-	26627737	RPE1	viability after 18 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.13988604393856852	[3982]	[887,1500]	0	hSpCas9	negative selection	1377422
23763463	23763486	18	+	26627737	RPE1	viability after 18 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.47451116086012773	[666]	[223,277]	3	hSpCas9	negative selection	1377423
23689842	23689865	18	-	26627737	HeLa	viability after 8 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-0.8600582031773973	[129]	[82,6,15]	-7	hSpCas9	negative selection	1459733
23748025	23748048	18	+	26627737	HeLa	viability after 8 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.26048273886521256	[781]	[606,374,292]	2	hSpCas9	negative selection	1459734
23749465	23749488	18	+	26627737	HeLa	viability after 8 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.9131841673529775	[234]	[102,21,48]	-7	hSpCas9	negative selection	1459735
23750974	23750997	18	+	26627737	HeLa	viability after 8 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.4328880856868191	[331]	[244,95,250]	4	hSpCas9	negative selection	1459736
23758392	23758415	18	-	26627737	HeLa	viability after 8 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.36557881677409965	[1631]	[1142,647,997]	3	hSpCas9	negative selection	1459737
23763463	23763486	18	+	26627737	HeLa	viability after 8 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-0.022572153215922125	[473]	[248,266,109]	0	hSpCas9	negative selection	1459738
23689842	23689865	18	-	26627737	HeLa	viability after 12 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-1.1575468163888456	[129]	[34,19,17]	-8	hSpCas9	negative selection	1542048
23748025	23748048	18	+	26627737	HeLa	viability after 12 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.3319604079183599	[781]	[376,401,440]	3	hSpCas9	negative selection	1542049
23749465	23749488	18	+	26627737	HeLa	viability after 12 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-1.7752263710799627	[234]	[24,37,20]	-9	hSpCas9	negative selection	1542050
23750974	23750997	18	+	26627737	HeLa	viability after 12 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.7510857659609327	[331]	[168,324,186]	6	hSpCas9	negative selection	1542051
23758392	23758415	18	-	26627737	HeLa	viability after 12 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.07683218943938552	[1631]	[1003,470,692]	0	hSpCas9	negative selection	1542052
23763463	23763486	18	+	26627737	HeLa	viability after 12 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-0.6866250158608265	[473]	[135,88,143]	-6	hSpCas9	negative selection	1542053
23689842	23689865	18	-	26627737	HeLa	viability after 15 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.2144034110416675	[129]	[123,26,29]	1	hSpCas9	negative selection	1624363
23748025	23748048	18	+	26627737	HeLa	viability after 15 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.25829268713335973	[781]	[329,245,217]	-2	hSpCas9	negative selection	1624364
23749465	23749488	18	+	26627737	HeLa	viability after 15 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.04995707553575501	[234]	[144,57,71]	0	hSpCas9	negative selection	1624365
23750974	23750997	18	+	26627737	HeLa	viability after 15 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.7172779141184433	[331]	[227,210,227]	5	hSpCas9	negative selection	1624366
23758392	23758415	18	-	26627737	HeLa	viability after 15 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.5504091307172145	[1631]	[1188,1082,616]	4	hSpCas9	negative selection	1624367
23763463	23763486	18	+	26627737	HeLa	viability after 15 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-1.1530005672280277	[473]	[33,91,138]	-7	hSpCas9	negative selection	1624368
23689842	23689865	18	-	26627737	HeLa	viability after 18 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.12360543249547451	[129]	[72,25,29]	1	hSpCas9	negative selection	1706678
23748025	23748048	18	+	26627737	HeLa	viability after 18 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.23117095552511224	[781]	[230,203,217]	-2	hSpCas9	negative selection	1706679
23749465	23749488	18	+	26627737	HeLa	viability after 18 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.06537404041766459	[234]	[96,45,71]	0	hSpCas9	negative selection	1706680
23750974	23750997	18	+	26627737	HeLa	viability after 18 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.6616418276936249	[331]	[145,162,227]	5	hSpCas9	negative selection	1706681
23758392	23758415	18	-	26627737	HeLa	viability after 18 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.5711590537697915	[1631]	[816,906,616]	4	hSpCas9	negative selection	1706682
23763463	23763486	18	+	26627737	HeLa	viability after 18 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-1.1441011565446	[473]	[23,75,138]	-7	hSpCas9	negative selection	1706683
23689842	23689865	18	-	26627737	HCT116	viability after 6 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.10585475195340122	[203]	[29,36]	0	hSpCas9	negative selection	1788993
23748025	23748048	18	+	26627737	HCT116	viability after 6 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.7369911354479237	[1868]	[310,101]	-4	hSpCas9	negative selection	1788994
23749465	23749488	18	+	26627737	HCT116	viability after 6 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.7048543581458098	[206]	[63,46]	4	hSpCas9	negative selection	1788995
23750974	23750997	18	+	26627737	HCT116	viability after 6 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	1.0901693704811795	[723]	[474,113]	6	hSpCas9	negative selection	1788996
23758392	23758415	18	-	26627737	HCT116	viability after 6 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.9887358117090015	[2532]	[951,700]	5	hSpCas9	negative selection	1788997
23763463	23763486	18	+	26627737	HCT116	viability after 6 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.15518803683231636	[578]	[72,116]	0	hSpCas9	negative selection	1788998
23689842	23689865	18	-	26627737	HCT116	viability after 8 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	1.0024417093557294	[32]	[30,25,51]	8	hSpCas9	negative selection	1871308
23748025	23748048	18	+	26627737	HCT116	viability after 8 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.057763178900802625	[878]	[365,541,485]	0	hSpCas9	negative selection	1871309
23749465	23749488	18	+	26627737	HCT116	viability after 8 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.2540921092179669	[162]	[128,30,66]	-3	hSpCas9	negative selection	1871310
23750974	23750997	18	+	26627737	HCT116	viability after 8 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.1720113326369952	[547]	[371,171,261]	-2	hSpCas9	negative selection	1871311
23758392	23758415	18	-	26627737	HCT116	viability after 8 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.4820034937215447	[1290]	[807,896,1268]	5	hSpCas9	negative selection	1871312
23763463	23763486	18	+	26627737	HCT116	viability after 8 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.18696128063097267	[374]	[235,259,209]	2	hSpCas9	negative selection	1871313
23689842	23689865	18	-	26627737	HCT116	viability after 9 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-3.204299392350049	[203]	[1,8]	-9	hSpCas9	negative selection	1953623
23748025	23748048	18	+	26627737	HCT116	viability after 9 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.05557486232518882	[1868]	[773,247]	0	hSpCas9	negative selection	1953624
23749465	23749488	18	+	26627737	HCT116	viability after 9 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.01932188884510122	[206]	[31,74]	0	hSpCas9	negative selection	1953625
23750974	23750997	18	+	26627737	HCT116	viability after 9 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	1.5049774207843878	[723]	[565,534]	8	hSpCas9	negative selection	1953626
23758392	23758415	18	-	26627737	HCT116	viability after 9 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.1457046149677188	[2532]	[745,749]	1	hSpCas9	negative selection	1953627
23763463	23763486	18	+	26627737	HCT116	viability after 9 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-0.963721736507762	[578]	[28,118]	-6	hSpCas9	negative selection	1953628
23689842	23689865	18	-	26627737	HCT116	viability after 12 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	1.0172935468704845	[32]	[24,26,53]	8	hSpCas9	negative selection	2035938
23748025	23748048	18	+	26627737	HCT116	viability after 12 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.349089297277688	[878]	[287,381,424]	-4	hSpCas9	negative selection	2035939
23749465	23749488	18	+	26627737	HCT116	viability after 12 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.10922278371497496	[162]	[156,70,42]	1	hSpCas9	negative selection	2035940
23750974	23750997	18	+	26627737	HCT116	viability after 12 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.09522525933398729	[547]	[342,232,341]	1	hSpCas9	negative selection	2035941
23758392	23758415	18	-	26627737	HCT116	viability after 12 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.42058572723980037	[1290]	[867,833,1023]	4	hSpCas9	negative selection	2035942
23763463	23763486	18	+	26627737	HCT116	viability after 12 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.25849597214594205	[374]	[216,281,210]	2	hSpCas9	negative selection	2035943
23689842	23689865	18	-	26627737	HCT116	viability after 15 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	1.5688239486511604	[32]	[45,29,90]	9	hSpCas9	negative selection	2118253
23748025	23748048	18	+	26627737	HCT116	viability after 15 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.3729090169140268	[878]	[480,345,353]	-4	hSpCas9	negative selection	2118254
23749465	23749488	18	+	26627737	HCT116	viability after 15 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.7022820705637743	[162]	[323,98,55]	6	hSpCas9	negative selection	2118255
23750974	23750997	18	+	26627737	HCT116	viability after 15 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.16763893393433982	[547]	[269,261,306]	-2	hSpCas9	negative selection	2118256
23758392	23758415	18	-	26627737	HCT116	viability after 15 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.11977605324193563	[1290]	[957,809,668]	1	hSpCas9	negative selection	2118257
23763463	23763486	18	+	26627737	HCT116	viability after 15 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-0.048046106472136696	[374]	[190,238,192]	0	hSpCas9	negative selection	2118258
23689842	23689865	18	-	26627737	HCT116	viability after 18 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.10797380844522042	[32]	[9,7,34]	1	hSpCas9	negative selection	2200568
23748025	23748048	18	+	26627737	HCT116	viability after 18 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.3737044741327502	[878]	[315,280,392]	-3	hSpCas9	negative selection	2200569
23749465	23749488	18	+	26627737	HCT116	viability after 18 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	1.123116058306597	[162]	[346,81,87]	8	hSpCas9	negative selection	2200570
23750974	23750997	18	+	26627737	HCT116	viability after 18 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.16771950102240085	[547]	[292,182,234]	-1	hSpCas9	negative selection	2200571
23758392	23758415	18	-	26627737	HCT116	viability after 18 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.6775235417092715	[1290]	[917,985,1095]	5	hSpCas9	negative selection	2200572
23763463	23763486	18	+	26627737	HCT116	viability after 18 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.6331725246064039	[374]	[367,352,109]	5	hSpCas9	negative selection	2200573
23915771	23915794	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGGTGGGCAGATCACCTGGGG	LAMA3	ENSG00000053747	-0.9435702514495408	[62,8]	[4,2]	-5	dCas9-VP64	positive selection	2385230
23691685	23691708	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTTGGCAGGCTGAAG	LAMA3	ENSG00000053747	2.180224224283918	[67,41]	[97,7]	7	dCas9-VP64	positive selection	2392972
23692502	23692525	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGGTGGGTGGATCATCTGAAG	LAMA3	ENSG00000053747	8.530822357030846	[1,11]	[5,1276]	9	dCas9-VP64	positive selection	2395219
23689423	23689446	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGCCGCGCGCCAGCAGACGG	LAMA3	ENSG00000053747	-0.06703712689820485	[90,44]	[21,4]	0	dCas9-VP64	positive selection	2397738
23689483	23689506	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGCTCTGGAACCTGCCGCGG	LAMA3	ENSG00000053747	0.3356040629395953	[64,82]	[30,8]	1	dCas9-VP64	positive selection	2397739
23689457	23689480	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGCGGGCACCAGCCGGATCAGG	LAMA3	ENSG00000053747	3.0863319863153658	[143,85]	[411,2]	8	dCas9-VP64	positive selection	2397740
23872846	23872869	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGAGCGGTGCGCTTACCTGCGGG	LAMA3	ENSG00000053747	1.1286551076054847	[35,102]	[62,1]	4	dCas9-VP64	positive selection	2397741
23872822	23872845	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	TAATTCCTGTGAGGTGGGGCGGG	LAMA3	ENSG00000053747	-0.7384327436775344	[30,61]	[4,6]	-4	dCas9-VP64	positive selection	2397742
23872871	23872894	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	TGTTATGTGCGCTCTGGCACAGG	LAMA3	ENSG00000053747	1.1329359820354714	[45,56]	[26,21]	4	dCas9-VP64	positive selection	2397743
23721071	23721094	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	CTCCAACTCCTGGGCTCAAGCAG	LAMA3	ENSG00000053747	-0.6994359689071444	[220,41]	[10,22]	-4	dCas9-VP64	positive selection	2419621
23892875	23892898	18	-	25494202	A375	resistance to PLX-4720 (puromycin)	GAGTTTCGCTCTTGTCACCCAAG	LAMA3	ENSG00000053747	0.7275722083534555	[14,18]	[4,6]	3	dCas9-VP64	positive selection	2454148
23700906	23700929	18	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTGGG	LAMA3	ENSG00000053747	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469924
23915771	23915794	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGGTGGGCAGATCACCTGGGG	LAMA3	ENSG00000053747	-1.0522246340753525	[77,52]	[9,9]	-8	dCas9-VP64	positive selection	2480485
23691685	23691708	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTTGGCAGGCTGAAG	LAMA3	ENSG00000053747	0.5215654761973469	[134,134]	[72,52]	4	dCas9-VP64	positive selection	2488227
23692502	23692525	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGGTGGGTGGATCATCTGAAG	LAMA3	ENSG00000053747	0.06463753928220184	[94,68]	[22,31]	0	dCas9-VP64	positive selection	2490474
23689423	23689446	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGCCGCGCGCCAGCAGACGG	LAMA3	ENSG00000053747	-0.3575021909076499	[78,117]	[16,31]	-4	dCas9-VP64	positive selection	2492993
23689483	23689506	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGCTCTGGAACCTGCCGCGG	LAMA3	ENSG00000053747	4.619752654479854	[208,135]	[451,2283]	9	dCas9-VP64	positive selection	2492994
23689457	23689480	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGCGGGCACCAGCCGGATCAGG	LAMA3	ENSG00000053747	-0.9684388113566889	[28,44]	[4,5]	-8	dCas9-VP64	positive selection	2492995
23872846	23872869	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGAGCGGTGCGCTTACCTGCGGG	LAMA3	ENSG00000053747	1.5988352340104233	[91,140]	[207,27]	8	dCas9-VP64	positive selection	2492996
23872822	23872845	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	TAATTCCTGTGAGGTGGGGCGGG	LAMA3	ENSG00000053747	0.9661738733378826	[197,20]	[137,8]	6	dCas9-VP64	positive selection	2492997
23872871	23872894	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	TGTTATGTGCGCTCTGGCACAGG	LAMA3	ENSG00000053747	-0.4362443457369009	[229,46]	[52,14]	-4	dCas9-VP64	positive selection	2492998
23721071	23721094	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	CTCCAACTCCTGGGCTCAAGCAG	LAMA3	ENSG00000053747	0.2833956541738802	[148,47]	[40,36]	2	dCas9-VP64	positive selection	2514876
23892875	23892898	18	-	25494202	A375	resistance to PLX-4720 (zeocin)	GAGTTTCGCTCTTGTCACCCAAG	LAMA3	ENSG00000053747	0.3552301064276102	[39,27]	[14,12]	3	dCas9-VP64	positive selection	2549403
23700906	23700929	18	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTGGG	LAMA3	ENSG00000053747	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565179
23876323	23876346	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAAAGGCTTGTATACCGGACGG	LAMA3	ENSG00000053747	0.7247283820624053	[3,3]	[3,6]	9	hSpCas9	positive selection	2998776
23881952	23881975	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	-1.1361017038093553	[2,2]	[0,0]	-9	hSpCas9	positive selection	2998777
23903105	23903128	18	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGATGGAGAAAAGCCAGAAGG	LAMA3	ENSG00000053747	-0.05635420847638983	[3,2]	[3,1]	-1	hSpCas9	positive selection	2998778
23873106	23873129	18	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTAGCCCAGACACTGCCCCAGGG	LAMA3	ENSG00000053747	-0.33084703844246793	[3,3]	[3,1]	-5	hSpCas9	positive selection	2998779
23876323	23876346	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAAAGGCTTGTATACCGGACGG	LAMA3	ENSG00000053747	0.017989147150150292	[3,3]	[3,1]	0	hSpCas9	positive selection	3066634
23881952	23881975	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	-0.26425287857359314	[2,2]	[2,0]	-4	hSpCas9	positive selection	3066635
23903105	23903128	18	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGATGGAGAAAAGCCAGAAGG	LAMA3	ENSG00000053747	-0.13119294336500142	[3,3]	[2,1]	-2	hSpCas9	positive selection	3066636
23873106	23873129	18	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTAGCCCAGACACTGCCCCAGGG	LAMA3	ENSG00000053747	-0.026842360808211438	[3,3]	[3,2]	0	hSpCas9	positive selection	3066637
23689775	23689798		-	24336571	A375	resistance to PLX after 7 days	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.09443157618334008	[21,20]	[21,23]	3	hSpCas9	positive selection	3124057
23747980	23748003		+	24336571	A375	resistance to PLX after 7 days	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	-0.021197597012381664	[73,62]	[64,68]	0	hSpCas9	positive selection	3124058
23881952	23881975		-	24336571	A375	resistance to PLX after 7 days	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	-0.19276104967307206	[5,5]	[5,4]	-6	hSpCas9	positive selection	3124059
23689847	23689870		-	24336571	A375	resistance to PLX after 7 days	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.053260036244191504	[11,11]	[11,11]	2	hSpCas9	positive selection	3124060
23881987	23882010		+	24336571	A375	resistance to PLX after 7 days	TACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.3077837301501072	[24,19]	[29,25]	8	hSpCas9	positive selection	3124061
23876352	23876375		-	24336571	A375	resistance to PLX after 7 days	TGAATGTCCGTTGCAATTGCAGG	LAMA3	ENSG00000053747	-0.11366361723664453	[24,22]	[22,20]	-4	hSpCas9	positive selection	3124062
23748042	23748065		-	24336571	A375	resistance to PLX after 7 days	TTACGAGCAAAATATTGCCATGG	LAMA3	ENSG00000053747	-0.04853214023795671	[19,23]	[21,19]	-1	hSpCas9	positive selection	3124063
23876303	23876326		-	24336571	A375	resistance to PLX after 7 days	TTATGATCCCGATAGTATCCAGG	LAMA3	ENSG00000053747	-0.029470801951907655	[5,4]	[4,4]	-1	hSpCas9	positive selection	3124064
23689775	23689798		-	24336571	A375	resistance to PLX after 14 days	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	-0.5453393306786551	[25,22]	[5,8]	-6	hSpCas9	positive selection	3181850
23747980	23748003		+	24336571	A375	resistance to PLX after 14 days	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.01713061267348248	[80,81]	[44,31]	0	hSpCas9	positive selection	3181851
23881952	23881975		-	24336571	A375	resistance to PLX after 14 days	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	0.5634253595708005	[4,4]	[3,2]	5	hSpCas9	positive selection	3181852
23689847	23689870		-	24336571	A375	resistance to PLX after 14 days	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	-0.33710825372552133	[14,19]	[5,5]	-4	hSpCas9	positive selection	3181853
23881987	23882010		+	24336571	A375	resistance to PLX after 14 days	TACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.2252375855937232	[30,24]	[13,15]	2	hSpCas9	positive selection	3181854
23876352	23876375		-	24336571	A375	resistance to PLX after 14 days	TGAATGTCCGTTGCAATTGCAGG	LAMA3	ENSG00000053747	0.7717833098504348	[15,16]	[10,14]	6	hSpCas9	positive selection	3181855
23748042	23748065		-	24336571	A375	resistance to PLX after 14 days	TTACGAGCAAAATATTGCCATGG	LAMA3	ENSG00000053747	0.15615104638318866	[22,28]	[10,15]	1	hSpCas9	positive selection	3181856
23876303	23876326		-	24336571	A375	resistance to PLX after 14 days	TTATGATCCCGATAGTATCCAGG	LAMA3	ENSG00000053747	-0.914264834255917	[6,8]	[1,1]	-9	hSpCas9	positive selection	3181857
23689775	23689798		-	24336571	A375	viability after 7 days	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.29592924188844616	[17]	[21,20]	4	hSpCas9	negative selection	3239643
23747980	23748003		+	24336571	A375	viability after 7 days	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.6568508778083364	[45]	[73,62]	8	hSpCas9	negative selection	3239644
23881952	23881975		-	24336571	A375	viability after 7 days	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	0.7492007294858458	[3]	[5,5]	9	hSpCas9	negative selection	3239645
23689847	23689870		-	24336571	A375	viability after 7 days	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	-0.4692182092806138	[17]	[11,11]	-6	hSpCas9	negative selection	3239646
23881987	23882010		+	24336571	A375	viability after 7 days	TACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.38221422833058727	[17]	[24,19]	6	hSpCas9	negative selection	3239647
23876352	23876375		-	24336571	A375	viability after 7 days	TGAATGTCCGTTGCAATTGCAGG	LAMA3	ENSG00000053747	0.4129492579955936	[18]	[24,22]	6	hSpCas9	negative selection	3239648
23748042	23748065		-	24336571	A375	viability after 7 days	TTACGAGCAAAATATTGCCATGG	LAMA3	ENSG00000053747	-0.026904790857205207	[22]	[19,23]	0	hSpCas9	negative selection	3239649
23876303	23876326		-	24336571	A375	viability after 7 days	TTATGATCCCGATAGTATCCAGG	LAMA3	ENSG00000053747	-0.6193236156049418	[8]	[5,4]	-7	hSpCas9	negative selection	3239650
23689775	23689798		-	24336571	A375	viability after 14 days	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.5126187981221598	[17]	[25,22]	6	hSpCas9	negative selection	3297436
23747980	23748003		+	24336571	A375	viability after 14 days	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.9149720099438212	[45]	[80,81]	9	hSpCas9	negative selection	3297437
23881952	23881975		-	24336571	A375	viability after 14 days	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	0.4714155823426591	[3]	[4,4]	6	hSpCas9	negative selection	3297438
23689847	23689870		-	24336571	A375	viability after 14 days	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.0794383673369023	[17]	[14,19]	1	hSpCas9	negative selection	3297439
23881987	23882010		+	24336571	A375	viability after 14 days	TACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.6831907500229718	[17]	[30,24]	8	hSpCas9	negative selection	3297440
23876352	23876375		-	24336571	A375	viability after 14 days	TGAATGTCCGTTGCAATTGCAGG	LAMA3	ENSG00000053747	-0.11471769217039024	[18]	[15,16]	-1	hSpCas9	negative selection	3297441
23748042	23748065		-	24336571	A375	viability after 14 days	TTACGAGCAAAATATTGCCATGG	LAMA3	ENSG00000053747	0.2365554842185691	[22]	[22,28]	3	hSpCas9	negative selection	3297442
23876303	23876326		-	24336571	A375	viability after 14 days	TTATGATCCCGATAGTATCCAGG	LAMA3	ENSG00000053747	-0.041666774835326104	[8]	[6,8]	0	hSpCas9	negative selection	3297443
23749464	23749487	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	3.3504356158373163	[14,14]	[0,0]	9	hSpCas9	positive selection	3376688
23747980	23748003	18	+	27383988	293T	resistance to West Nile virus (flavivirus)	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	1.148801754667666	[551,551]	[7,7]	5	hSpCas9	positive selection	3376689
23747991	23748014	18	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	1.0285075209499543	[74,74]	[0,0]	5	hSpCas9	positive selection	3376690
23876322	23876345	18	+	26780180	HT29	viability (Avana library 4 designs)	ATAAAGGCTTGTATACCGGACGG	LAMA3	ENSG00000053747	0.894788707901979	[]	[]	3	hSpCas9	negative selection	3436280
23881952	23881975	18	-	26780180	HT29	viability (Avana library 4 designs)	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	2.24766331148598	[]	[]	7	hSpCas9	negative selection	3436281
23903104	23903127	18	+	26780180	HT29	viability (Avana library 4 designs)	GCTGATGGAGAAAAGCCAGAAGG	LAMA3	ENSG00000053747	1.84496324673726	[]	[]	7	hSpCas9	negative selection	3436282
23873106	23873129	18	-	26780180	HT29	viability (Avana library 4 designs)	GTAGCCCAGACACTGCCCCAGGG	LAMA3	ENSG00000053747	0.347263960831458	[]	[]	1	hSpCas9	negative selection	3436283
23873106	23873129	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTAGCCCAGACACTGCCCCAGGG	LAMA3	ENSG00000053747	5.05374182292485	[]	[]	8	hSpCas9	negative selection	3524389
23876322	23876345	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	ATAAAGGCTTGTATACCGGACGG	LAMA3	ENSG00000053747	-1.99786770996203	[]	[]	-2	hSpCas9	negative selection	3524390
23903104	23903127	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGATGGAGAAAAGCCAGAAGG	LAMA3	ENSG00000053747	-1.73603290419878	[]	[]	-2	hSpCas9	negative selection	3524391
23881952	23881975	18	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	3.22148144479546	[]	[]	5	hSpCas9	negative selection	3524392
23881935	23881958	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-5.43104783693835	[]	[]	-5	hSpCas9	negative selection	3524393
23873125	23873148	18	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACAGTTCACAGCAGCAAAGGG	LAMA3	ENSG00000053747	-1.43330468202795	[]	[]	-2	hSpCas9	negative selection	3524394
23873106	23873129	18	-	26780180	A375	viability (Avana lentiGuide)	GTAGCCCAGACACTGCCCCAGGG	LAMA3	ENSG00000053747	5.45506323531252	[]	[]	5	hSpCas9	negative selection	3633048
23876322	23876345	18	+	26780180	A375	viability (Avana lentiGuide)	ATAAAGGCTTGTATACCGGACGG	LAMA3	ENSG00000053747	-4.89924134839569	[]	[]	-8	hSpCas9	negative selection	3633049
23903104	23903127	18	+	26780180	A375	viability (Avana lentiGuide)	GCTGATGGAGAAAAGCCAGAAGG	LAMA3	ENSG00000053747	-10.0752906643652	[]	[]	-9	hSpCas9	negative selection	3633050
23881952	23881975	18	-	26780180	A375	viability (Avana lentiGuide)	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	7.43781599314921	[]	[]	6	hSpCas9	negative selection	3633051
23881935	23881958	18	+	26780180	A375	viability (Avana lentiGuide)	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.323861034946496	[]	[]	0	hSpCas9	negative selection	3633052
23873125	23873148	18	+	26780180	A375	viability (Avana lentiGuide)	CTACAGTTCACAGCAGCAAAGGG	LAMA3	ENSG00000053747	-1.82827672626088	[]	[]	-3	hSpCas9	negative selection	3633053
23873106	23873129	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTAGCCCAGACACTGCCCCAGGG	LAMA3	ENSG00000053747	0.18906637821944722	[4]	[3,5]	5	hSpCas9	positive selection	3741707
23876322	23876345	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAAAGGCTTGTATACCGGACGG	LAMA3	ENSG00000053747	-0.2845738781861087	[5]	[4,3]	-4	hSpCas9	positive selection	3741708
23903104	23903127	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGATGGAGAAAAGCCAGAAGG	LAMA3	ENSG00000053747	-0.03150963013820918	[4]	[5,3]	0	hSpCas9	positive selection	3741709
23881952	23881975	18	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	0.03436729396452182	[4]	[4,3]	0	hSpCas9	positive selection	3741710
23881935	23881958	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.45021396562504556	[4]	[2,2]	-6	hSpCas9	positive selection	3741711
23873125	23873148	18	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACAGTTCACAGCAGCAAAGGG	LAMA3	ENSG00000053747	-0.39439777033118867	[4]	[2,3]	-5	hSpCas9	positive selection	3741712
23873106	23873129	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTAGCCCAGACACTGCCCCAGGG	LAMA3	ENSG00000053747	-0.07314405537845267	[5]	[4,3]	-1	hSpCas9	positive selection	3850314
23876322	23876345	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAAAGGCTTGTATACCGGACGG	LAMA3	ENSG00000053747	-0.2760585252311118	[5]	[3,3]	-4	hSpCas9	positive selection	3850315
23903104	23903127	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGATGGAGAAAAGCCAGAAGG	LAMA3	ENSG00000053747	-0.32171266272635074	[4]	[1,3]	-4	hSpCas9	positive selection	3850316
23881952	23881975	18	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	0.17480389993931728	[5]	[4,4]	4	hSpCas9	positive selection	3850317
23881935	23881958	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.15559786917151466	[5]	[5,4]	3	hSpCas9	positive selection	3850318
23873125	23873148	18	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACAGTTCACAGCAGCAAAGGG	LAMA3	ENSG00000053747	0.27720233067353867	[5]	[4,5]	7	hSpCas9	positive selection	3850319
23749464	23749487	18	+	26780180	A375	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.573402459363522	[]	[]	1	hSpCas9	negative selection	3956110
23749513	23749536	18	+	26780180	A375	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	1.17644578196178	[]	[]	6	hSpCas9	negative selection	3956111
23689775	23689798	18	-	26780180	A375	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.231775890893849	[]	[]	0	hSpCas9	negative selection	3956112
23747980	23748003	18	+	26780180	A375	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.480953393984605	[]	[]	1	hSpCas9	negative selection	3956113
23747991	23748014	18	-	26780180	A375	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	1.57607051982283	[]	[]	8	hSpCas9	negative selection	3956114
23689847	23689870	18	-	26780180	A375	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.0695329615366508	[]	[]	0	hSpCas9	negative selection	3956115
23749464	23749487	18	+	26780180	HT29	viability (GeCKOv2 library)	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.482517752608099	[]	[]	1	hSpCas9	negative selection	4064076
23749513	23749536	18	+	26780180	HT29	viability (GeCKOv2 library)	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	1.44358878857424	[]	[]	7	hSpCas9	negative selection	4064077
23689775	23689798	18	-	26780180	HT29	viability (GeCKOv2 library)	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	1.44642554345438	[]	[]	7	hSpCas9	negative selection	4064078
23747980	23748003	18	+	26780180	HT29	viability (GeCKOv2 library)	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.296092663378978	[]	[]	0	hSpCas9	negative selection	4064079
23747991	23748014	18	-	26780180	HT29	viability (GeCKOv2 library)	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.569503372018151	[]	[]	2	hSpCas9	negative selection	4064080
23689847	23689870	18	-	26780180	HT29	viability (GeCKOv2 library)	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	-0.229445929531516	[]	[]	-6	hSpCas9	negative selection	4064081
23689775	23689798	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.18511734350879672	[4]	[4,2]	5	hSpCas9	positive selection	4148062
23747980	23748003	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.5847613398015125	[5]	[7,5]	9	hSpCas9	positive selection	4148063
23881952	23881975	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	0.03698310171740016	[1]	[0,1]	0	hSpCas9	positive selection	4148064
23689847	23689870	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.19536696241996526	[3]	[2,2]	5	hSpCas9	positive selection	4148065
23881987	23882010	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.6426963518279883	[4]	[5,3]	9	hSpCas9	positive selection	4148066
23876352	23876375	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGAATGTCCGTTGCAATTGCAGG	LAMA3	ENSG00000053747	0.8794127483047992	[4]	[7,3]	9	hSpCas9	positive selection	4148067
23748042	23748065	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTACGAGCAAAATATTGCCATGG	LAMA3	ENSG00000053747	0.07547789230970547	[4]	[2,3]	2	hSpCas9	positive selection	4148068
23876303	23876326	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TTATGATCCCGATAGTATCCAGG	LAMA3	ENSG00000053747	-0.46951040258033716	[2]	[1,0]	-8	hSpCas9	positive selection	4148069
23689775	23689798	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	1.0530704587592739	[4]	[4,3,5,3]	7	hSpCas9	positive selection	4212084
23747980	23748003	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.676345240323687	[5]	[5,4,5,2]	4	hSpCas9	positive selection	4212085
23881952	23881975	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCGTTCACAGTGCTCTCCCGCGG	LAMA3	ENSG00000053747	-0.10210733374947183	[3]	[3,0,0,0]	-1	hSpCas9	positive selection	4212086
23689847	23689870	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.22583892530065602	[4]	[4,0,4,0]	1	hSpCas9	positive selection	4212087
23881987	23882010	18	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	1.1440830093074001	[4]	[3,3,2,4]	8	hSpCas9	positive selection	4212088
23876352	23876375	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGAATGTCCGTTGCAATTGCAGG	LAMA3	ENSG00000053747	-0.10349255769630594	[3]	[2,0,2,0]	-1	hSpCas9	positive selection	4212089
23748042	23748065	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTACGAGCAAAATATTGCCATGG	LAMA3	ENSG00000053747	0.1874508861835784	[4]	[5,2,1,0]	1	hSpCas9	positive selection	4212090
23876303	23876326	18	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TTATGATCCCGATAGTATCCAGG	LAMA3	ENSG00000053747	-0.2147549391354059	[3]	[1,0,1,0]	-3	hSpCas9	positive selection	4212091
23689775	23689798	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.5995887105440041	[3]	[4,4]	9	hSpCas9	positive selection	4279617
23689847	23689870	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.44068712343938055	[3]	[4,3]	8	hSpCas9	positive selection	4279618
23749513	23749536	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.008205075518880223	[4]	[3,2]	0	hSpCas9	positive selection	4279619
23749464	23749487	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.08221955603352704	[0]	[0,0]	1	hSpCas9	positive selection	4343873
23747980	23748003	18	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.4580807206393741	[4]	[4,4]	8	hSpCas9	positive selection	4343874
23747991	23748014	18	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.18356599532601806	[2]	[2,1]	-4	hSpCas9	positive selection	4343875
23876302	23876324	18	-	27760321	OCIAML3	viability	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.22291981974877428	[173,149]	[76,148]	-2	hSpCas9	negative selection	4413667
23876337	23876359	18	-	27760321	OCIAML3	viability	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	0.24054590397022552	[440,336]	[393,307]	3	hSpCas9	negative selection	4413668
23881988	23882010	18	+	27760321	OCIAML3	viability	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	-0.36597571506497706	[468,466]	[270,302]	-4	hSpCas9	negative selection	4413669
23890106	23890128	18	-	27760321	OCIAML3	viability	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.9991994807104743	[832,687]	[1110,1277]	9	hSpCas9	negative selection	4413670
23895052	23895074	18	-	27760321	OCIAML3	viability	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	0.09531610501011095	[313,290]	[168,361]	1	hSpCas9	negative selection	4413671
23876302	23876324	18	-	27760321	OCIAML2	viability	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	0.6142900196173628	[173,149]	[212,182]	8	hSpCas9	negative selection	4497130
23876337	23876359	18	-	27760321	OCIAML2	viability	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	0.32894413132780165	[440,336]	[336,464]	4	hSpCas9	negative selection	4497131
23881988	23882010	18	+	27760321	OCIAML2	viability	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.14014596502552246	[468,466]	[405,434]	1	hSpCas9	negative selection	4497132
23890106	23890128	18	-	27760321	OCIAML2	viability	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.43657819673688625	[832,687]	[767,908]	6	hSpCas9	negative selection	4497133
23895052	23895074	18	-	27760321	OCIAML2	viability	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	0.07284937900260535	[313,290]	[215,311]	0	hSpCas9	negative selection	4497134
23876302	23876324	18	-	27760321	MV411	viability	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.34130958508367915	[173,149]	[18,181]	-2	hSpCas9	negative selection	4580593
23876337	23876359	18	-	27760321	MV411	viability	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	0.44149122326046053	[440,336]	[251,486]	3	hSpCas9	negative selection	4580594
23881988	23882010	18	+	27760321	MV411	viability	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.6344057557957012	[468,466]	[591,313]	5	hSpCas9	negative selection	4580595
23890106	23890128	18	-	27760321	MV411	viability	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	1.3651053880205621	[832,687]	[1385,1137]	8	hSpCas9	negative selection	4580596
23895052	23895074	18	-	27760321	MV411	viability	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	-0.15947202442395902	[313,290]	[129,251]	-1	hSpCas9	negative selection	4580597
23876302	23876324	18	-	27760321	HL60	viability	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.9874034151045705	[173,149]	[51,81]	-7	hSpCas9	negative selection	4664056
23876337	23876359	18	-	27760321	HL60	viability	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	0.5978718228255635	[440,336]	[484,468]	7	hSpCas9	negative selection	4664057
23881988	23882010	18	+	27760321	HL60	viability	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	-0.4067305638413623	[468,466]	[198,384]	-4	hSpCas9	negative selection	4664058
23890106	23890128	18	-	27760321	HL60	viability	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.08195399046758434	[832,687]	[523,792]	1	hSpCas9	negative selection	4664059
23895052	23895074	18	-	27760321	HL60	viability	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	-0.6166529485034986	[313,290]	[100,224]	-6	hSpCas9	negative selection	4664060
23876302	23876324	18	-	27760321	HT1080	viability	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.7911698136430023	[149,116]	[3,59]	-3	hSpCas9	negative selection	4747519
23876337	23876359	18	-	27760321	HT1080	viability	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.02805586035170443	[336,262]	[89,146]	0	hSpCas9	negative selection	4747520
23881988	23882010	18	+	27760321	HT1080	viability	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	1.298071931274028	[466,364]	[260,567]	7	hSpCas9	negative selection	4747521
23890106	23890128	18	-	27760321	HT1080	viability	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.6394304698038914	[687,536]	[265,504]	3	hSpCas9	negative selection	4747522
23895052	23895074	18	-	27760321	HT1080	viability	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	0.6301202079943576	[290,226]	[152,166]	3	hSpCas9	negative selection	4747523
23876302	23876324	18	-	27760321	HT29	viability after 7 days	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.15153011221610146	[149,116]	[135,115,206]	-2	hSpCas9	negative selection	4830982
23876337	23876359	18	-	27760321	HT29	viability after 7 days	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	0.15609317077970053	[336,262]	[640,379,301]	2	hSpCas9	negative selection	4830983
23881988	23882010	18	+	27760321	HT29	viability after 7 days	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	-0.3253878503625842	[466,364]	[353,339,570]	-5	hSpCas9	negative selection	4830984
23890106	23890128	18	-	27760321	HT29	viability after 7 days	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.22150287646699895	[687,536]	[1206,846,745]	3	hSpCas9	negative selection	4830985
23895052	23895074	18	-	27760321	HT29	viability after 7 days	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	-0.49429475232600306	[290,226]	[323,245,153]	-6	hSpCas9	negative selection	4830986
23876302	23876324	18	-	27760321	HT29	viability after 25 days	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	0.1770163029517957	[149,116]	[140,206,170]	1	hSpCas9	negative selection	4914445
23876337	23876359	18	-	27760321	HT29	viability after 25 days	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.17981551047802058	[336,262]	[290,273,347]	-2	hSpCas9	negative selection	4914446
23881988	23882010	18	+	27760321	HT29	viability after 25 days	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.055080020064474655	[466,364]	[440,475,575]	0	hSpCas9	negative selection	4914447
23890106	23890128	18	-	27760321	HT29	viability after 25 days	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.7494717338824989	[687,536]	[906,1173,1497]	8	hSpCas9	negative selection	4914448
23895052	23895074	18	-	27760321	HT29	viability after 25 days	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	0.01904168311918375	[290,226]	[366,176,356]	0	hSpCas9	negative selection	4914449
23876302	23876324	18	-	27760321	HT29	viability after 22 days	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	0.41856654580467434	[149,116]	[164,240,213]	4	hSpCas9	negative selection	4997908
23876337	23876359	18	-	27760321	HT29	viability after 22 days	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.12425484899562411	[336,262]	[510,261,174]	-1	hSpCas9	negative selection	4997909
23881988	23882010	18	+	27760321	HT29	viability after 22 days	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	-0.46069806550312214	[466,364]	[312,325,410]	-4	hSpCas9	negative selection	4997910
23890106	23890128	18	-	27760321	HT29	viability after 22 days	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.7202682713175369	[687,536]	[851,1189,1468]	7	hSpCas9	negative selection	4997911
23895052	23895074	18	-	27760321	HT29	viability after 22 days	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	-0.07860572398039667	[290,226]	[247,271,331]	-1	hSpCas9	negative selection	4997912
23876302	23876324	18	-	27760321	HT29	viability after 19 days	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	1.419884706869958	[149,116]	[149,634,412]	9	hSpCas9	negative selection	5081371
23876337	23876359	18	-	27760321	HT29	viability after 19 days	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.652014030519318	[336,262]	[338,256,76]	-5	hSpCas9	negative selection	5081372
23881988	23882010	18	+	27760321	HT29	viability after 19 days	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	-0.20113575933489367	[466,364]	[326,536,369]	-2	hSpCas9	negative selection	5081373
23890106	23890128	18	-	27760321	HT29	viability after 19 days	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.6466634252037865	[687,536]	[915,1676,692]	6	hSpCas9	negative selection	5081374
23895052	23895074	18	-	27760321	HT29	viability after 19 days	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	0.508973673804882	[290,226]	[221,375,636]	5	hSpCas9	negative selection	5081375
23876302	23876324	18	-	27760321	HT29	viability after 16 days	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.07905110963491069	[149,116]	[136,92,194]	-1	hSpCas9	negative selection	5164834
23876337	23876359	18	-	27760321	HT29	viability after 16 days	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.08531322250489015	[336,262]	[335,465,144]	-1	hSpCas9	negative selection	5164835
23881988	23882010	18	+	27760321	HT29	viability after 16 days	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.14069969818743122	[466,364]	[564,407,573]	1	hSpCas9	negative selection	5164836
23890106	23890128	18	-	27760321	HT29	viability after 16 days	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.5441753870776899	[687,536]	[1240,1015,762]	6	hSpCas9	negative selection	5164837
23895052	23895074	18	-	27760321	HT29	viability after 16 days	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	-0.37220446563567944	[290,226]	[156,271,234]	-4	hSpCas9	negative selection	5164838
23876302	23876324	18	-	27760321	HT29	viability after 13 days	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.5115756408622723	[149,116]	[70,197,59]	-5	hSpCas9	negative selection	5248297
23876337	23876359	18	-	27760321	HT29	viability after 13 days	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.03959522335124427	[336,262]	[639,222,162]	0	hSpCas9	negative selection	5248298
23881988	23882010	18	+	27760321	HT29	viability after 13 days	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.015457686939391702	[466,364]	[691,402,374]	0	hSpCas9	negative selection	5248299
23890106	23890128	18	-	27760321	HT29	viability after 13 days	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.7553333930661733	[687,536]	[1200,1433,976]	8	hSpCas9	negative selection	5248300
23895052	23895074	18	-	27760321	HT29	viability after 13 days	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	-0.004019992234994496	[290,226]	[343,208,342]	0	hSpCas9	negative selection	5248301
23876302	23876324	18	-	27760321	HT29	viability after 10 days	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-0.17183443806642318	[149,116]	[225,155,63]	-2	hSpCas9	negative selection	5331760
23876337	23876359	18	-	27760321	HT29	viability after 10 days	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.08624975980269134	[336,262]	[364,418,277]	-1	hSpCas9	negative selection	5331761
23881988	23882010	18	+	27760321	HT29	viability after 10 days	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	-0.21635630084376023	[466,364]	[442,403,491]	-3	hSpCas9	negative selection	5331762
23890106	23890128	18	-	27760321	HT29	viability after 10 days	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.4363303694571502	[687,536]	[1100,1239,774]	6	hSpCas9	negative selection	5331763
23895052	23895074	18	-	27760321	HT29	viability after 10 days	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	-0.4686054200543158	[290,226]	[236,271,193]	-5	hSpCas9	negative selection	5331764
23876302	23876324	18	-	27760321	MOLM13	viability	ATGATCCCGATAGTATCCAGGG	LAMA3	ENSG00000053747	-2.3174746673561826	[173,149]	[0,32]	-8	hSpCas9	negative selection	5415223
23876337	23876359	18	-	27760321	MOLM13	viability	TTGCAGGGAACACACCGTCCGG	LAMA3	ENSG00000053747	-0.5572430712502795	[440,336]	[194,107]	-4	hSpCas9	negative selection	5415224
23881988	23882010	18	+	27760321	MOLM13	viability	ACTATGGCAACGCCGTCCACGG	LAMA3	ENSG00000053747	0.3643933261748421	[468,466]	[105,540]	2	hSpCas9	negative selection	5415225
23890106	23890128	18	-	27760321	MOLM13	viability	TCGGCCTTACCTCCAGTCAGGG	LAMA3	ENSG00000053747	0.981450155990373	[832,687]	[1080,640]	7	hSpCas9	negative selection	5415226
23895052	23895074	18	-	27760321	MOLM13	viability	CCGCAGGGGATTTACCCTCAGG	LAMA3	ENSG00000053747	0.37141758898857513	[313,290]	[229,212]	2	hSpCas9	negative selection	5415227
23689629	23689652	18	+	27661255	K562	viability	GGTGCCCCCGAGCCCCTCTGCGG	LAMA3	ENSG00000053747	-3.645246887250436	[329,449]	[27,21]	-9	dCas9-KRAB	negative selection	5489701
23689782	23689805	18	+	27661255	K562	viability	GGCGACCGCTCGGGATCCCGGGG	LAMA3	ENSG00000053747	0.023238599524910808	[1099,1212]	[1049,840]	0	dCas9-KRAB	negative selection	5489702
23689474	23689497	18	-	27661255	K562	viability	GGAACCTGCCGCGGCTGGAGCGG	LAMA3	ENSG00000053747	0.09260012381431426	[1152,1248]	[1129,928]	3	dCas9-KRAB	negative selection	5489703
23689775	23689798	18	-	27260156	BXPC3	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.23478935169049964	[856]	[1026,829,1124,1272]	5	hSpCas9	negative selection	5552077
23689847	23689870	18	-	27260156	BXPC3	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.795262630253169	[757]	[1324,1435,1176,1576]	9	hSpCas9	negative selection	5552078
23749513	23749536	18	+	27260156	BXPC3	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.11482512497412434	[1091]	[879,1038,1036,1304]	-3	hSpCas9	negative selection	5552079
23749464	23749487	18	+	27260156	BXPC3	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.3456900646770924	[53]	[51,46,17,60]	-7	hSpCas9	negative selection	5616333
23747980	23748003	18	+	27260156	BXPC3	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.13599275726405669	[1224]	[1270,1253,1373,1791]	3	hSpCas9	negative selection	5616334
23747991	23748014	18	-	27260156	BXPC3	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.27457112625687263	[315]	[309,383,470,448]	6	hSpCas9	negative selection	5616335
23689775	23689798	18	-	27260156	A673	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.27665983255593585	[856]	[1220,1099,1313,1354]	6	hSpCas9	negative selection	5673328
23689847	23689870	18	-	27260156	A673	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.5398142676111383	[757]	[1564,1193,1342,1212]	9	hSpCas9	negative selection	5673329
23749513	23749536	18	+	27260156	A673	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.2277549162788275	[1091]	[1271,1043,1041,1139]	-5	hSpCas9	negative selection	5673330
23749464	23749487	18	+	27260156	A673	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.021239972767450155	[53]	[49,29,111,69]	0	hSpCas9	negative selection	5737584
23747980	23748003	18	+	27260156	A673	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.17264021268765806	[1224]	[1758,1555,1543,1791]	4	hSpCas9	negative selection	5737585
23747991	23748014	18	-	27260156	A673	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.17187856025512915	[315]	[418,505,390,387]	4	hSpCas9	negative selection	5737586
23689775	23689798	18	-	27260156	A375	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.29078961250597934	[856]	[1185,1453,1135,1156]	4	hSpCas9	negative selection	5794579
23689847	23689870	18	-	27260156	A375	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.7490280233987755	[757]	[1603,1688,1509,1205]	9	hSpCas9	negative selection	5794580
23749513	23749536	18	+	27260156	A375	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.17946033165926778	[1091]	[1601,1577,1262,1358]	2	hSpCas9	negative selection	5794581
23749464	23749487	18	+	27260156	A375	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.5585184720027137	[53]	[12,118,1,46]	-6	hSpCas9	negative selection	5858835
23747980	23748003	18	+	27260156	A375	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.5332351302846243	[1224]	[1762,2603,1989,1997]	7	hSpCas9	negative selection	5858836
23747991	23748014	18	-	27260156	A375	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.3715104634280504	[315]	[478,464,536,430]	5	hSpCas9	negative selection	5858837
23689775	23689798	18	-	27260156	COLO741	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.09725084494185132	[856]	[1060,1223,1213]	2	hSpCas9	negative selection	5915830
23689847	23689870	18	-	27260156	COLO741	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.4109233616713669	[757]	[1444,1166,1262]	8	hSpCas9	negative selection	5915831
23749513	23749536	18	+	27260156	COLO741	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.012168942565758734	[1091]	[1396,1604,1228]	0	hSpCas9	negative selection	5915832
23749464	23749487	18	+	27260156	COLO741	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.260901682978703	[53]	[54,155,37]	5	hSpCas9	negative selection	5980086
23747980	23748003	18	+	27260156	COLO741	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.213844811491404	[1224]	[1759,1998,1687]	4	hSpCas9	negative selection	5980087
23747991	23748014	18	-	27260156	COLO741	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.017369649635606055	[315]	[488,477,274]	0	hSpCas9	negative selection	5980088
23689775	23689798	18	-	27260156	CAL120	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.22215034607876094	[856]	[1189,1217,1313]	3	hSpCas9	negative selection	6037081
23689847	23689870	18	-	27260156	CAL120	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.6290917459072557	[757]	[1765,1249,1406]	8	hSpCas9	negative selection	6037082
23749513	23749536	18	+	27260156	CAL120	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.15363031949025174	[1091]	[1307,1465,908]	-2	hSpCas9	negative selection	6037083
23749464	23749487	18	+	27260156	CAL120	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.6311837434789025	[53]	[169,97,54]	8	hSpCas9	negative selection	6101337
23747980	23748003	18	+	27260156	CAL120	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.4120267022431945	[1224]	[2120,2233,1747]	6	hSpCas9	negative selection	6101338
23747991	23748014	18	-	27260156	CAL120	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.1504514644233096	[315]	[769,356,235]	2	hSpCas9	negative selection	6101339
23689775	23689798	18	-	27260156	CADOES1	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.3319025997430859	[856]	[805,905,1327,971]	5	hSpCas9	negative selection	6158332
23689847	23689870	18	-	27260156	CADOES1	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.6026103575177356	[757]	[878,1138,1182,1081]	8	hSpCas9	negative selection	6158333
23749513	23749536	18	+	27260156	CADOES1	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.1664667436900371	[1091]	[1265,1229,955,1105]	3	hSpCas9	negative selection	6158334
23749464	23749487	18	+	27260156	CADOES1	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.18594164630089471	[53]	[74,77,31,42]	3	hSpCas9	negative selection	6222588
23747980	23748003	18	+	27260156	CADOES1	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.39141894141017386	[1224]	[1376,1580,1453,1568]	6	hSpCas9	negative selection	6222589
23747991	23748014	18	-	27260156	CADOES1	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.04165363026385116	[315]	[293,390,180,275]	0	hSpCas9	negative selection	6222590
23689775	23689798	18	-	27260156	EWS502	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.3647608864865516	[856]	[1110,1208,1001,1365]	6	hSpCas9	negative selection	6279583
23689847	23689870	18	-	27260156	EWS502	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.7760220535731716	[757]	[1602,1190,1411,1259]	9	hSpCas9	negative selection	6279584
23749513	23749536	18	+	27260156	EWS502	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.07068986912713005	[1091]	[939,1240,1169,1061]	-1	hSpCas9	negative selection	6279585
23749464	23749487	18	+	27260156	EWS502	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.46824807260709056	[53]	[49,18,26,70]	-7	hSpCas9	negative selection	6343839
23747980	23748003	18	+	27260156	EWS502	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.39135786906947123	[1224]	[1491,1557,2026,1763]	7	hSpCas9	negative selection	6343840
23747991	23748014	18	-	27260156	EWS502	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.07085167514295343	[315]	[238,535,347,282]	1	hSpCas9	negative selection	6343841
23689775	23689798	18	-	27260156	EW8	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.2671663874001472	[856]	[918,981,669,807]	5	hSpCas9	negative selection	6400834
23689847	23689870	18	-	27260156	EW8	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.6986278887536558	[757]	[1077,871,1105,918]	9	hSpCas9	negative selection	6400835
23749513	23749536	18	+	27260156	EW8	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.03593928405985425	[1091]	[915,855,955,890]	0	hSpCas9	negative selection	6400836
23749464	23749487	18	+	27260156	EW8	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.03671631352111415	[53]	[22,74,15,58]	0	hSpCas9	negative selection	6465090
23747980	23748003	18	+	27260156	EW8	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.4355381321880163	[1224]	[1396,1410,1265,1311]	7	hSpCas9	negative selection	6465091
23747991	23748014	18	-	27260156	EW8	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.1727031819624984	[315]	[332,257,255,316]	3	hSpCas9	negative selection	6465092
23689775	23689798	18	-	27260156	CORL105	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.22078572666860719	[856]	[1050,1278,1349,1018]	4	hSpCas9	negative selection	6522085
23689847	23689870	18	-	27260156	CORL105	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.6376000836462951	[757]	[1692,1182,1594,1099]	9	hSpCas9	negative selection	6522086
23749513	23749536	18	+	27260156	CORL105	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.19139883957614234	[1091]	[1016,949,1403,1150]	-4	hSpCas9	negative selection	6522087
23749464	23749487	18	+	27260156	CORL105	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.31966576668322366	[53]	[49,46,52,52]	-5	hSpCas9	negative selection	6586341
23747980	23748003	18	+	27260156	CORL105	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.029663945009174908	[1224]	[1381,1306,1680,1518]	0	hSpCas9	negative selection	6586342
23747991	23748014	18	-	27260156	CORL105	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.10656574203753405	[315]	[438,379,373,397]	2	hSpCas9	negative selection	6586343
23689775	23689798	18	-	27260156	HS294T	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.1559298417326248	[856]	[464,318,358,315]	2	hSpCas9	negative selection	6643336
23689847	23689870	18	-	27260156	HS294T	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.5518690462822117	[757]	[406,533,343,430]	7	hSpCas9	negative selection	6643337
23749513	23749536	18	+	27260156	HS294T	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.14829602404595965	[1091]	[413,460,445,571]	2	hSpCas9	negative selection	6643338
23749464	23749487	18	+	27260156	HS294T	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	1.9731361030452546	[53]	[27,223,38,27]	9	hSpCas9	negative selection	6707592
23747980	23748003	18	+	27260156	HS294T	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.3432165586979605	[1224]	[612,675,475,638]	4	hSpCas9	negative selection	6707593
23747991	23748014	18	-	27260156	HS294T	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.26101532303081043	[315]	[220,111,144,91]	3	hSpCas9	negative selection	6707594
23689775	23689798	18	-	27260156	HCC44	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.18585417382103164	[856]	[1323,1077,973,1028]	3	hSpCas9	negative selection	6764587
23689847	23689870	18	-	27260156	HCC44	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.47793785979674064	[757]	[1371,1140,1085,1172]	7	hSpCas9	negative selection	6764588
23749513	23749536	18	+	27260156	HCC44	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.08092448034859068	[1091]	[1089,1136,1368,1622]	1	hSpCas9	negative selection	6764589
23749464	23749487	18	+	27260156	HCC44	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.4865210710594896	[53]	[62,11,14,83]	-6	hSpCas9	negative selection	6828843
23747980	23748003	18	+	27260156	HCC44	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.26836458430096766	[1224]	[1799,1590,1705,1595]	4	hSpCas9	negative selection	6828844
23747991	23748014	18	-	27260156	HCC44	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.0928250816096522	[315]	[690,219,345,311]	1	hSpCas9	negative selection	6828845
23689775	23689798	18	-	27260156	G402	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.6219108290332441	[856]	[1292,2121,1328,1667]	7	hSpCas9	negative selection	6885838
23689847	23689870	18	-	27260156	G402	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.7289427174439352	[757]	[1522,1544,1710,1354]	8	hSpCas9	negative selection	6885839
23749513	23749536	18	+	27260156	G402	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.2636788905440528	[1091]	[1800,1834,1703,1118]	3	hSpCas9	negative selection	6885840
23749464	23749487	18	+	27260156	G402	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.530047669944389	[53]	[19,89,41,29]	-6	hSpCas9	negative selection	6950094
23747980	23748003	18	+	27260156	G402	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.39608293089330493	[1224]	[2417,1981,1849,1689]	5	hSpCas9	negative selection	6950095
23747991	23748014	18	-	27260156	G402	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.2751698425261796	[315]	[925,436,475,107]	3	hSpCas9	negative selection	6950096
23689775	23689798	18	-	27260156	L33	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.4173112465507617	[856]	[1228,413,716,1194]	8	hSpCas9	negative selection	7007089
23689847	23689870	18	-	27260156	L33	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.4878360968886045	[757]	[950,448,757,1002]	8	hSpCas9	negative selection	7007090
23749513	23749536	18	+	27260156	L33	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.07489029764962174	[1091]	[1005,401,701,1043]	-2	hSpCas9	negative selection	7007091
23749464	23749487	18	+	27260156	L33	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.11196797101455136	[53]	[45,17,46,68]	2	hSpCas9	negative selection	7071345
23747980	23748003	18	+	27260156	L33	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.08225657081923932	[1224]	[1427,494,745,1359]	1	hSpCas9	negative selection	7071346
23747991	23748014	18	-	27260156	L33	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.19395043382530064	[315]	[295,118,181,228]	-4	hSpCas9	negative selection	7071347
23689775	23689798	18	-	27260156	K562	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.46268537716449953	[856]	[1213,862,842,1247]	6	hSpCas9	negative selection	7128340
23689847	23689870	18	-	27260156	K562	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.544813373798675	[757]	[1116,1245,770,829]	7	hSpCas9	negative selection	7128341
23749513	23749536	18	+	27260156	K562	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.32596603501237564	[1091]	[1057,1681,981,1150]	4	hSpCas9	negative selection	7128342
23749464	23749487	18	+	27260156	K562	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.43272802511729	[53]	[17,144,41,54]	5	hSpCas9	negative selection	7192596
23747980	23748003	18	+	27260156	K562	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.614895751312833	[1224]	[1673,1819,1604,1572]	7	hSpCas9	negative selection	7192597
23747991	23748014	18	-	27260156	K562	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.6088044122544193	[315]	[395,341,406,542]	7	hSpCas9	negative selection	7192598
23689775	23689798	18	-	27260156	HT29	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.09920038535512299	[856]	[924,1218,1209,1097]	2	hSpCas9	negative selection	7249591
23689847	23689870	18	-	27260156	HT29	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.377487154720208	[757]	[1209,1494,940,1163]	7	hSpCas9	negative selection	7249592
23749513	23749536	18	+	27260156	HT29	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.06194381653050485	[1091]	[1389,1370,1277,1079]	-1	hSpCas9	negative selection	7249593
23749464	23749487	18	+	27260156	HT29	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.4265079852708169	[53]	[36,123,26,154]	8	hSpCas9	negative selection	7313847
23747980	23748003	18	+	27260156	HT29	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.304406866574934	[1224]	[1699,2040,1876,1742]	6	hSpCas9	negative selection	7313848
23747991	23748014	18	-	27260156	HT29	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.13206467886755024	[315]	[428,468,406,384]	2	hSpCas9	negative selection	7313849
23689775	23689798	18	-	27260156	MHHES1	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.28838959559463284	[856]	[1074,1404,1199,1048]	5	hSpCas9	negative selection	7370842
23689847	23689870	18	-	27260156	MHHES1	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.3959109589125215	[757]	[1221,1241,874,1144]	7	hSpCas9	negative selection	7370843
23749513	23749536	18	+	27260156	MHHES1	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.07224747042511304	[1091]	[1070,1378,1419,1261]	1	hSpCas9	negative selection	7370844
23749464	23749487	18	+	27260156	MHHES1	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.530037622273551	[53]	[59,81,32,6]	-7	hSpCas9	negative selection	7435098
23747980	23748003	18	+	27260156	MHHES1	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.3969907235529919	[1224]	[1689,2019,2046,1539]	7	hSpCas9	negative selection	7435099
23747991	23748014	18	-	27260156	MHHES1	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.2693842075493201	[315]	[414,613,451,277]	5	hSpCas9	negative selection	7435100
23689775	23689798	18	-	27260156	MEWO	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.054705010445099456	[856]	[1132,682,740]	1	hSpCas9	negative selection	7492093
23689847	23689870	18	-	27260156	MEWO	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.5082374089476781	[757]	[1261,758,1054]	8	hSpCas9	negative selection	7492094
23749513	23749536	18	+	27260156	MEWO	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.019853301537428036	[1091]	[1209,799,1052]	0	hSpCas9	negative selection	7492095
23749464	23749487	18	+	27260156	MEWO	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.40576486151477376	[53]	[61,41,14]	-7	hSpCas9	negative selection	7556349
23747980	23748003	18	+	27260156	MEWO	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.289881744180722	[1224]	[1479,1461,1275]	6	hSpCas9	negative selection	7556350
23747991	23748014	18	-	27260156	MEWO	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.262678467429557	[315]	[220,306,205]	-5	hSpCas9	negative selection	7556351
23689775	23689798	18	-	27260156	LNCAPCLONEFGC	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.567814664248914	[856]	[1124,1023,1433,1069]	8	hSpCas9	negative selection	7613344
23689847	23689870	18	-	27260156	LNCAPCLONEFGC	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.6206051693440421	[757]	[958,1001,1354,955]	8	hSpCas9	negative selection	7613345
23749513	23749536	18	+	27260156	LNCAPCLONEFGC	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.10028052651740027	[1091]	[1019,939,1372,962]	1	hSpCas9	negative selection	7613346
23749464	23749487	18	+	27260156	LNCAPCLONEFGC	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.021564437794676206	[53]	[31,76,53,28]	0	hSpCas9	negative selection	7677600
23747980	23748003	18	+	27260156	LNCAPCLONEFGC	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.3555397142501917	[1224]	[1218,1383,1746,1382]	5	hSpCas9	negative selection	7677601
23747991	23748014	18	-	27260156	LNCAPCLONEFGC	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.11404884082110822	[315]	[205,201,472,212]	-2	hSpCas9	negative selection	7677602
23689775	23689798	18	-	27260156	PANC0327	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.2823198040743248	[856]	[1005,901,1043,760]	4	hSpCas9	negative selection	7734595
23689847	23689870	18	-	27260156	PANC0327	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.7150167025424302	[757]	[858,966,1439,1152]	8	hSpCas9	negative selection	7734596
23749513	23749536	18	+	27260156	PANC0327	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.221334411898499	[1091]	[1234,1118,1010,1167]	3	hSpCas9	negative selection	7734597
23749464	23749487	18	+	27260156	PANC0327	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-1.1605708162769925	[53]	[43,18,19,4]	-9	hSpCas9	negative selection	7798851
23747980	23748003	18	+	27260156	PANC0327	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.4975349667175992	[1224]	[1523,1102,1839,1732]	7	hSpCas9	negative selection	7798852
23747991	23748014	18	-	27260156	PANC0327	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.05826815741361724	[315]	[171,261,181,454]	-1	hSpCas9	negative selection	7798853
23689775	23689798	18	-	27260156	NCIH2009	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.5445783942784045	[856]	[2373,1441,1549]	7	hSpCas9	negative selection	7855846
23689847	23689870	18	-	27260156	NCIH2009	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	1.1355583867933898	[757]	[2663,2325,2052]	9	hSpCas9	negative selection	7855847
23749513	23749536	18	+	27260156	NCIH2009	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.24798263606703763	[1091]	[2113,1874,1501]	3	hSpCas9	negative selection	7855848
23749464	23749487	18	+	27260156	NCIH2009	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.09608994904231283	[53]	[72,40,126]	1	hSpCas9	negative selection	7920102
23747980	23748003	18	+	27260156	NCIH2009	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.3165361464816776	[1224]	[2491,2180,1787]	4	hSpCas9	negative selection	7920103
23747991	23748014	18	-	27260156	NCIH2009	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.0522861927393079	[315]	[425,297,554]	0	hSpCas9	negative selection	7920104
23689775	23689798	18	-	27260156	NCIH1373	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.6695224702539321	[856]	[1897,1932,932,355]	6	hSpCas9	negative selection	7977097
23689847	23689870	18	-	27260156	NCIH1373	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.7830982146352504	[757]	[1481,1391,1867,282]	7	hSpCas9	negative selection	7977098
23749513	23749536	18	+	27260156	NCIH1373	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.4045365520917199	[1091]	[1981,1280,1511,473]	4	hSpCas9	negative selection	7977099
23749464	23749487	18	+	27260156	NCIH1373	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.16526868101437486	[53]	[111,5,33,20]	-2	hSpCas9	negative selection	8041353
23747980	23748003	18	+	27260156	NCIH1373	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.952282480939487	[1224]	[5056,1464,1726,762]	8	hSpCas9	negative selection	8041354
23747991	23748014	18	-	27260156	NCIH1373	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.4957704548126438	[315]	[295,210,238,70]	-5	hSpCas9	negative selection	8041355
23689775	23689798	18	-	27260156	PATU8902	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.5637753677786289	[856]	[2200,1481,1353,2151]	6	hSpCas9	negative selection	8098348
23689847	23689870	18	-	27260156	PATU8902	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.9428149796021027	[757]	[2783,2129,1310,2055]	8	hSpCas9	negative selection	8098349
23749513	23749536	18	+	27260156	PATU8902	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.19020396484764035	[1091]	[1467,2449,1487,1570]	2	hSpCas9	negative selection	8098350
23749464	23749487	18	+	27260156	PATU8902	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.3720496689180637	[53]	[161,24,25,205]	4	hSpCas9	negative selection	8162604
23747980	23748003	18	+	27260156	PATU8902	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.7246856881101034	[1224]	[3373,2847,2366,2769]	7	hSpCas9	negative selection	8162605
23747991	23748014	18	-	27260156	PATU8902	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.24740504007618302	[315]	[267,438,233,603]	-2	hSpCas9	negative selection	8162606
23689775	23689798	18	-	27260156	PANC1	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.2399391450358609	[856]	[781,1114,913,727]	4	hSpCas9	negative selection	8219599
23689847	23689870	18	-	27260156	PANC1	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.7597695658793856	[757]	[1066,1485,1102,855]	9	hSpCas9	negative selection	8219600
23749513	23749536	18	+	27260156	PANC1	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.1589592719290942	[1091]	[700,1000,831,846]	-3	hSpCas9	negative selection	8219601
23749464	23749487	18	+	27260156	PANC1	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	1.0374256166963356	[53]	[101,42,31,176]	9	hSpCas9	negative selection	8283855
23747980	23748003	18	+	27260156	PANC1	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.30342965234095365	[1224]	[1139,1731,1080,1307]	5	hSpCas9	negative selection	8283856
23747991	23748014	18	-	27260156	PANC1	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.018047458361348467	[315]	[250,310,162,338]	0	hSpCas9	negative selection	8283857
23689775	23689798	18	-	27260156	PANC0813	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.11363154660637032	[856]	[1250,1064,1011,1043]	1	hSpCas9	negative selection	8340850
23689847	23689870	18	-	27260156	PANC0813	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.05394735242378079	[757]	[947,745,964,1032]	0	hSpCas9	negative selection	8340851
23749513	23749536	18	+	27260156	PANC0813	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.07552443572336154	[1091]	[1269,1134,1618,1372]	1	hSpCas9	negative selection	8340852
23749464	23749487	18	+	27260156	PANC0813	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.046582891960727846	[53]	[110,41,11,98]	0	hSpCas9	negative selection	8405106
23747980	23748003	18	+	27260156	PANC0813	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.2795744690571471	[1224]	[2210,1776,1592,1460]	4	hSpCas9	negative selection	8405107
23747991	23748014	18	-	27260156	PANC0813	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.5730764036476883	[315]	[267,289,259,184]	-7	hSpCas9	negative selection	8405108
23689775	23689798	18	-	27260156	RDES	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.36183880210728236	[856]	[1133,1156,1516,1265]	6	hSpCas9	negative selection	8462101
23689847	23689870	18	-	27260156	RDES	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.7058577846992654	[757]	[1195,1434,1481,1607]	9	hSpCas9	negative selection	8462102
23749513	23749536	18	+	27260156	RDES	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.1677461942030387	[1091]	[1256,1180,1440,1841]	2	hSpCas9	negative selection	8462103
23749464	23749487	18	+	27260156	RDES	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.4813624441616504	[53]	[31,37,35,78]	-7	hSpCas9	negative selection	8526357
23747980	23748003	18	+	27260156	RDES	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.4898805411991012	[1224]	[1696,1806,2160,2323]	7	hSpCas9	negative selection	8526358
23747991	23748014	18	-	27260156	RDES	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.07000016677604382	[315]	[262,430,402,449]	1	hSpCas9	negative selection	8526359
23689775	23689798	18	-	27260156	PC3	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.08155755116457164	[856]	[676,709,1284,1108]	1	hSpCas9	negative selection	8583352
23689847	23689870	18	-	27260156	PC3	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.43090256257736914	[757]	[610,1013,1670,1119]	8	hSpCas9	negative selection	8583353
23749513	23749536	18	+	27260156	PC3	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.1598883562190343	[1091]	[683,832,1669,1013]	-4	hSpCas9	negative selection	8583354
23749464	23749487	18	+	27260156	PC3	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.1412918834614163	[53]	[36,61,162,17]	3	hSpCas9	negative selection	8647608
23747980	23748003	18	+	27260156	PC3	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.2509916990366985	[1224]	[811,1232,2407,1918]	5	hSpCas9	negative selection	8647609
23747991	23748014	18	-	27260156	PC3	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.18719977322579057	[315]	[186,590,435,276]	4	hSpCas9	negative selection	8647610
23689775	23689798	18	-	27260156	PATU8988T	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.591381258405704	[856]	[1203,1340,1274,1172]	8	hSpCas9	negative selection	8704603
23689847	23689870	18	-	27260156	PATU8988T	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.8749473572767982	[757]	[1338,1417,1404,1205]	9	hSpCas9	negative selection	8704604
23749513	23749536	18	+	27260156	PATU8988T	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.025958827968774134	[1091]	[1112,1074,857,1269]	0	hSpCas9	negative selection	8704605
23749464	23749487	18	+	27260156	PATU8988T	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.8390342337037437	[53]	[15,23,55,18]	-8	hSpCas9	negative selection	8768859
23747980	23748003	18	+	27260156	PATU8988T	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.32844769148248076	[1224]	[1657,1006,1614,1629]	5	hSpCas9	negative selection	8768860
23747991	23748014	18	-	27260156	PATU8988T	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.40773512495103814	[315]	[179,280,266,193]	-6	hSpCas9	negative selection	8768861
23689775	23689798	18	-	27260156	T47D	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.30622773006068826	[856]	[1220,1195,1185,1341]	6	hSpCas9	negative selection	8825854
23689847	23689870	18	-	27260156	T47D	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.524999124212124	[757]	[1319,1164,1245,1363]	9	hSpCas9	negative selection	8825855
23749513	23749536	18	+	27260156	T47D	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.18234887907905062	[1091]	[1141,996,1196,1158]	-4	hSpCas9	negative selection	8825856
23749464	23749487	18	+	27260156	T47D	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.17826960234495193	[53]	[39,50,42,89]	-4	hSpCas9	negative selection	8890110
23747980	23748003	18	+	27260156	T47D	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.2997313278563396	[1224]	[1718,1787,1597,1925]	6	hSpCas9	negative selection	8890111
23747991	23748014	18	-	27260156	T47D	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.12915916226679042	[315]	[360,349,462,440]	2	hSpCas9	negative selection	8890112
23689775	23689798	18	-	27260156	SU8686	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.43003020931304337	[856]	[1011,1159,908,1563]	7	hSpCas9	negative selection	8947105
23689847	23689870	18	-	27260156	SU8686	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.5304911974540533	[757]	[1100,870,1104,1321]	8	hSpCas9	negative selection	8947106
23749513	23749536	18	+	27260156	SU8686	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.15440800718534908	[1091]	[1385,864,1061,1577]	2	hSpCas9	negative selection	8947107
23749464	23749487	18	+	27260156	SU8686	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.750089386485389	[53]	[14,67,244,38]	9	hSpCas9	negative selection	9011361
23747980	23748003	18	+	27260156	SU8686	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.37385644614634406	[1224]	[1512,1507,1803,1461]	6	hSpCas9	negative selection	9011362
23747991	23748014	18	-	27260156	SU8686	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.09552728482763773	[315]	[335,296,301,418]	1	hSpCas9	negative selection	9011363
23689775	23689798	18	-	27260156	SKES1	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.2023634898537484	[856]	[995,1189,926,853]	4	hSpCas9	negative selection	9068356
23689847	23689870	18	-	27260156	SKES1	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.4701393449448389	[757]	[1132,1218,968,907]	8	hSpCas9	negative selection	9068357
23749513	23749536	18	+	27260156	SKES1	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.23527948821911715	[1091]	[981,1183,731,844]	-5	hSpCas9	negative selection	9068358
23749464	23749487	18	+	27260156	SKES1	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.2760581934743227	[53]	[20,92,38,28]	-6	hSpCas9	negative selection	9132612
23747980	23748003	18	+	27260156	SKES1	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.13435900271416967	[1224]	[1366,1446,1434,1140]	3	hSpCas9	negative selection	9132613
23747991	23748014	18	-	27260156	SKES1	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.020223114016582278	[315]	[279,343,374,277]	0	hSpCas9	negative selection	9132614
23689775	23689798	18	-	27260156	TOV112D	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.4588762129429028	[856]	[1304,1447,1237,812]	8	hSpCas9	negative selection	9189607
23689847	23689870	18	-	27260156	TOV112D	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.6494416227023904	[757]	[1221,1275,1245,1044]	9	hSpCas9	negative selection	9189608
23749513	23749536	18	+	27260156	TOV112D	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.3342159551152708	[1091]	[851,1023,729,898]	-6	hSpCas9	negative selection	9189609
23749464	23749487	18	+	27260156	TOV112D	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.19530697714068213	[53]	[12,47,107,17]	-4	hSpCas9	negative selection	9253863
23747980	23748003	18	+	27260156	TOV112D	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.1159674673164004	[1224]	[1493,1574,940,1378]	2	hSpCas9	negative selection	9253864
23747991	23748014	18	-	27260156	TOV112D	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.2982778940174935	[315]	[314,705,369,240]	5	hSpCas9	negative selection	9253865
23689775	23689798	18	-	27260156	TC71	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.2508779911881992	[856]	[1106,1166,857,1257]	6	hSpCas9	negative selection	9310858
23689847	23689870	18	-	27260156	TC71	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.42077273199372767	[757]	[1058,1238,861,1205]	8	hSpCas9	negative selection	9310859
23749513	23749536	18	+	27260156	TC71	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	-0.2419501898977363	[1091]	[986,873,1059,1038]	-6	hSpCas9	negative selection	9310860
23749464	23749487	18	+	27260156	TC71	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	0.5374408763276262	[53]	[99,91,74,67]	9	hSpCas9	negative selection	9375114
23747980	23748003	18	+	27260156	TC71	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.14995285631279387	[1224]	[1455,1389,1398,1592]	4	hSpCas9	negative selection	9375115
23747991	23748014	18	-	27260156	TC71	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	0.2515341330899725	[315]	[436,416,363,394]	6	hSpCas9	negative selection	9375116
23689775	23689798	18	-	27260156	TC32	viability	ATCCCGAGCGGTCGCCCCGCAGG	LAMA3	ENSG00000053747	0.30579334453604645	[856]	[908,714,1242,1229]	5	hSpCas9	negative selection	9432109
23689847	23689870	18	-	27260156	TC32	viability	GGCCCAAATCCTCGCCGCCTCGG	LAMA3	ENSG00000053747	0.5232796920452295	[757]	[862,884,1155,1235]	8	hSpCas9	negative selection	9432110
23749513	23749536	18	+	27260156	TC32	viability	ATATTCCCGTATTGTACCTTTGG	LAMA3	ENSG00000053747	0.08989552509747045	[1091]	[962,885,1551,1074]	1	hSpCas9	negative selection	9432111
23749464	23749487	18	+	27260156	TC32	viability	AGGCAAATATGGCTGTCACCCGG	LAMA3	ENSG00000053747	-0.18680518215306208	[53]	[29,29,89,40]	-3	hSpCas9	negative selection	9496365
23747980	23748003	18	+	27260156	TC32	viability	ATTCTCCTCGCCCTGATCTTTGG	LAMA3	ENSG00000053747	0.33852889227915184	[1224]	[1387,1167,1700,1646]	6	hSpCas9	negative selection	9496366
23747991	23748014	18	-	27260156	TC32	viability	CTTTCCAAGACCCAAAGATCAGG	LAMA3	ENSG00000053747	-0.006502038092220053	[315]	[272,220,426,297]	0	hSpCas9	negative selection	9496367
23689842	23689865	18	-	27869803	HPAFII	viability after 27 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.42956637341935466	[89]	[72,55,NaN]	3	hSpCas9	negative selection	9564249
23748025	23748048	18	+	27869803	HPAFII	viability after 27 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.5195956011570821	[605]	[519,403,NaN]	4	hSpCas9	negative selection	9564250
23749465	23749488	18	+	27869803	HPAFII	viability after 27 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.14155573906804508	[135]	[102,32,NaN]	-1	hSpCas9	negative selection	9564251
23750974	23750997	18	+	27869803	HPAFII	viability after 27 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.9819072527188542	[416]	[62,150,NaN]	-6	hSpCas9	negative selection	9564252
23758392	23758415	18	-	27869803	HPAFII	viability after 27 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.6631971049738907	[1283]	[738,1343,NaN]	5	hSpCas9	negative selection	9564253
23763463	23763486	18	+	27869803	HPAFII	viability after 27 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.5878418212536716	[275]	[174,253,NaN]	5	hSpCas9	negative selection	9564254
23689842	23689865	18	-	27869803	HPAFII	viability after 15 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	0.07071343968146437	[89]	[116,91,NaN]	0	hSpCas9	negative selection	9646698
23748025	23748048	18	+	27869803	HPAFII	viability after 15 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.16184681212493013	[605]	[965,580,NaN]	1	hSpCas9	negative selection	9646699
23749465	23749488	18	+	27869803	HPAFII	viability after 15 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.4579007293660349	[135]	[246,18,NaN]	-5	hSpCas9	negative selection	9646700
23750974	23750997	18	+	27869803	HPAFII	viability after 15 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-0.2202162813198052	[416]	[409,368,NaN]	-3	hSpCas9	negative selection	9646701
23758392	23758415	18	-	27869803	HPAFII	viability after 15 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.11182829706197106	[1283]	[1907,1231,NaN]	1	hSpCas9	negative selection	9646702
23763463	23763486	18	+	27869803	HPAFII	viability after 15 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.5138096968902099	[275]	[351,467,NaN]	6	hSpCas9	negative selection	9646703
23689842	23689865	18	-	27869803	ASPC1	viability after 36 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-0.6022060634747937	[171]	[38,77,8]	-5	hSpCas9	negative selection	9729147
23748025	23748048	18	+	27869803	ASPC1	viability after 36 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-1.0987285435106071	[1506]	[303,212,227]	-8	hSpCas9	negative selection	9729148
23749465	23749488	18	+	27869803	ASPC1	viability after 36 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.5091310065293662	[270]	[0,24,313]	5	hSpCas9	negative selection	9729149
23750974	23750997	18	+	27869803	ASPC1	viability after 36 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	0.48097239044708007	[1085]	[483,716,405]	5	hSpCas9	negative selection	9729150
23758392	23758415	18	-	27869803	ASPC1	viability after 36 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.20199292274351288	[2530]	[1688,1132,440]	2	hSpCas9	negative selection	9729151
23763463	23763486	18	+	27869803	ASPC1	viability after 36 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-0.28931164857302244	[543]	[31,214,192]	-3	hSpCas9	negative selection	9729152
23689842	23689865	18	-	27869803	PATU8988S	viability after 35 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-1.6754608834948257	[209]	[16,35,NaN]	-8	hSpCas9	negative selection	9811596
23748025	23748048	18	+	27869803	PATU8988S	viability after 35 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.9214858305079248	[1174]	[183,315,NaN]	-7	hSpCas9	negative selection	9811597
23749465	23749488	18	+	27869803	PATU8988S	viability after 35 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-2.219779253103516	[317]	[24,29,NaN]	-9	hSpCas9	negative selection	9811598
23750974	23750997	18	+	27869803	PATU8988S	viability after 35 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-1.1781364302116415	[932]	[191,139,NaN]	-8	hSpCas9	negative selection	9811599
23758392	23758415	18	-	27869803	PATU8988S	viability after 35 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	-0.47161281965891	[2076]	[496,709,NaN]	-5	hSpCas9	negative selection	9811600
23763463	23763486	18	+	27869803	PATU8988S	viability after 35 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-1.717903752056284	[538]	[61,69,NaN]	-8	hSpCas9	negative selection	9811601
23689842	23689865	18	-	27869803	PATU8988S	viability after 31 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	-1.6720692025032362	[209]	[9,46,NaN]	-8	hSpCas9	negative selection	9894045
23748025	23748048	18	+	27869803	PATU8988S	viability after 31 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	-0.9502920606482376	[1174]	[212,279,NaN]	-7	hSpCas9	negative selection	9894046
23749465	23749488	18	+	27869803	PATU8988S	viability after 31 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-1.530855555411947	[317]	[53,30,NaN]	-8	hSpCas9	negative selection	9894047
23750974	23750997	18	+	27869803	PATU8988S	viability after 31 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-1.621403539856983	[932]	[101,144,NaN]	-8	hSpCas9	negative selection	9894048
23758392	23758415	18	-	27869803	PATU8988S	viability after 31 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	-0.26323775142576866	[2076]	[598,805,NaN]	-3	hSpCas9	negative selection	9894049
23763463	23763486	18	+	27869803	PATU8988S	viability after 31 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	-1.2177966779668576	[538]	[109,69,NaN]	-8	hSpCas9	negative selection	9894050
23689842	23689865	18	-	27869803	HPAFII	viability after 35 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	1.1274617074801767	[89]	[123,71,NaN]	7	hSpCas9	negative selection	9976494
23748025	23748048	18	+	27869803	HPAFII	viability after 35 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.8072574067007956	[605]	[446,637,NaN]	5	hSpCas9	negative selection	9976495
23749465	23749488	18	+	27869803	HPAFII	viability after 35 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	0.23742946391844377	[135]	[59,104,NaN]	1	hSpCas9	negative selection	9976496
23750974	23750997	18	+	27869803	HPAFII	viability after 35 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-1.4933765368434606	[416]	[34,119,NaN]	-7	hSpCas9	negative selection	9976497
23758392	23758415	18	-	27869803	HPAFII	viability after 35 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.6422150260531034	[1283]	[601,1478,NaN]	4	hSpCas9	negative selection	9976498
23763463	23763486	18	+	27869803	HPAFII	viability after 35 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.9516674275314085	[275]	[162,390,NaN]	6	hSpCas9	negative selection	9976499
23689842	23689865	18	-	27869803	HPAFII	viability after 31 days	AAATCCTCGCCGCCTCGGCCAGG	LAMA3	ENSG00000053747	1.2421261860889063	[89]	[118,119,NaN]	8	hSpCas9	negative selection	10058943
23748025	23748048	18	+	27869803	HPAFII	viability after 31 days	TTGGAAGCACCTACTCACCATGG	LAMA3	ENSG00000053747	0.5675384774731509	[605]	[470,539,NaN]	4	hSpCas9	negative selection	10058944
23749465	23749488	18	+	27869803	HPAFII	viability after 31 days	GGCAAATATGGCTGTCACCCGGG	LAMA3	ENSG00000053747	-0.6055029386868793	[135]	[64,33,NaN]	-4	hSpCas9	negative selection	10058945
23750974	23750997	18	+	27869803	HPAFII	viability after 31 days	CACCCTGAGGGAGTTTACCAAGG	LAMA3	ENSG00000053747	-1.6437761497304173	[416]	[38,113,NaN]	-7	hSpCas9	negative selection	10058946
23758392	23758415	18	-	27869803	HPAFII	viability after 31 days	CTGGCATTCACACCGAAACCTGG	LAMA3	ENSG00000053747	0.5064384526877719	[1283]	[635,1445,NaN]	3	hSpCas9	negative selection	10058947
23763463	23763486	18	+	27869803	HPAFII	viability after 31 days	GCAGGCAAGCTTGAATACCCAGG	LAMA3	ENSG00000053747	0.6839379087465216	[275]	[155,349,NaN]	5	hSpCas9	negative selection	10058948
23881935	23881958	18	+	28162770	P31FUJ	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.2251211077176417	[173]	[238]	2	hSpCas9	negative selection	10182800
23904551	23904574	18	+	28162770	P31FUJ	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.017642160829208144	[210]	[250]	0	hSpCas9	negative selection	10182801
23904606	23904629	18	-	28162770	P31FUJ	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.4207473815641901	[266]	[419]	5	hSpCas9	negative selection	10182802
23916641	23916664	18	+	28162770	P31FUJ	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.6005479261761699	[54]	[97]	7	hSpCas9	negative selection	10182803
23882004	23882027	18	-	28162770	P31FUJ	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	0.8021315856950084	[203]	[417]	8	hSpCas9	negative selection	10182804
23894965	23894988	18	-	28162770	P31FUJ	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	0.9172232395902289	[72]	[161]	9	hSpCas9	negative selection	10182805
23895028	23895051	18	+	28162770	P31FUJ	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.8922930155671542	[413]	[902]	8	hSpCas9	negative selection	10182806
23903061	23903084	18	-	28162770	P31FUJ	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.2338403291180162	[253]	[350]	2	hSpCas9	negative selection	10182807
23904013	23904036	18	+	28162770	P31FUJ	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.031471398605760315	[413]	[475]	0	hSpCas9	negative selection	10182808
23904033	23904056	18	+	28162770	P31FUJ	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-0.8457790813051314	[51]	[33]	-6	hSpCas9	negative selection	10182809
23881935	23881958	18	+	28162770	TF1	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10352166
23904551	23904574	18	+	28162770	TF1	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	NaN	[NaN]	[303]	1	hSpCas9	negative selection	10352167
23904606	23904629	18	-	28162770	TF1	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	NaN	[NaN]	[142]	1	hSpCas9	negative selection	10352168
23916641	23916664	18	+	28162770	TF1	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	NaN	[NaN]	[105]	1	hSpCas9	negative selection	10352169
23882004	23882027	18	-	28162770	TF1	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	NaN	[NaN]	[272]	1	hSpCas9	negative selection	10352170
23894965	23894988	18	-	28162770	TF1	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10352171
23895028	23895051	18	+	28162770	TF1	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	NaN	[NaN]	[433]	1	hSpCas9	negative selection	10352172
23903061	23903084	18	-	28162770	TF1	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10352173
23904013	23904036	18	+	28162770	TF1	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	NaN	[NaN]	[425]	1	hSpCas9	negative selection	10352174
23904033	23904056	18	+	28162770	TF1	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	NaN	[NaN]	[66]	1	hSpCas9	negative selection	10352175
23881935	23881958	18	+	28162770	SKM1	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.5299836307215365	[37]	[96]	5	hSpCas9	negative selection	10521532
23904551	23904574	18	+	28162770	SKM1	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.3384629741712407	[50]	[113]	3	hSpCas9	negative selection	10521533
23904606	23904629	18	-	28162770	SKM1	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.9419309437444701	[52]	[179]	8	hSpCas9	negative selection	10521534
23916641	23916664	18	+	28162770	SKM1	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.11659775731385125	[11]	[22]	1	hSpCas9	negative selection	10521535
23882004	23882027	18	-	28162770	SKM1	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.3365748708517637	[59]	[83]	-3	hSpCas9	negative selection	10521536
23894965	23894988	18	-	28162770	SKM1	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	-0.2914869813232257	[17]	[25]	-2	hSpCas9	negative selection	10521537
23895028	23895051	18	+	28162770	SKM1	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.589629199813589	[105]	[281]	6	hSpCas9	negative selection	10521538
23903061	23903084	18	-	28162770	SKM1	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	-0.10473190519671917	[58]	[96]	-1	hSpCas9	negative selection	10521539
23904013	23904036	18	+	28162770	SKM1	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.19467704312462475	[85]	[173]	2	hSpCas9	negative selection	10521540
23904033	23904056	18	+	28162770	SKM1	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-0.27451390271951226	[12]	[18]	-2	hSpCas9	negative selection	10521541
23881935	23881958	18	+	28162770	SKM1	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.5299836307215365	[37]	[96]	5	hSpCas9	negative selection	10690898
23904551	23904574	18	+	28162770	SKM1	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.3384629741712407	[50]	[113]	3	hSpCas9	negative selection	10690899
23904606	23904629	18	-	28162770	SKM1	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.9419309437444701	[52]	[179]	8	hSpCas9	negative selection	10690900
23916641	23916664	18	+	28162770	SKM1	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.11659775731385125	[11]	[22]	1	hSpCas9	negative selection	10690901
23882004	23882027	18	-	28162770	SKM1	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.3365748708517637	[59]	[83]	-3	hSpCas9	negative selection	10690902
23894965	23894988	18	-	28162770	SKM1	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	-0.2914869813232257	[17]	[25]	-2	hSpCas9	negative selection	10690903
23895028	23895051	18	+	28162770	SKM1	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.589629199813589	[105]	[281]	6	hSpCas9	negative selection	10690904
23903061	23903084	18	-	28162770	SKM1	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	-0.10473190519671917	[58]	[96]	-1	hSpCas9	negative selection	10690905
23904013	23904036	18	+	28162770	SKM1	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.19467704312462475	[85]	[173]	2	hSpCas9	negative selection	10690906
23904033	23904056	18	+	28162770	SKM1	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-0.27451390271951226	[12]	[18]	-2	hSpCas9	negative selection	10690907
23881935	23881958	18	+	28162770	PL21	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.24043297689666132	[170]	[62]	-2	hSpCas9	negative selection	10860264
23904551	23904574	18	+	28162770	PL21	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.2815672138331663	[154]	[81]	2	hSpCas9	negative selection	10860265
23904606	23904629	18	-	28162770	PL21	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	-0.5048535899386061	[237]	[72]	-4	hSpCas9	negative selection	10860266
23916641	23916664	18	+	28162770	PL21	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	-0.25237259020818636	[51]	[18]	-2	hSpCas9	negative selection	10860267
23882004	23882027	18	-	28162770	PL21	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.17722746682346877	[251]	[96]	-1	hSpCas9	negative selection	10860268
23894965	23894988	18	-	28162770	PL21	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	0.3636383467721995	[74]	[41]	3	hSpCas9	negative selection	10860269
23895028	23895051	18	+	28162770	PL21	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.17581028512757946	[298]	[146]	1	hSpCas9	negative selection	10860270
23903061	23903084	18	-	28162770	PL21	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.995449194886331	[188]	[163]	8	hSpCas9	negative selection	10860271
23904013	23904036	18	+	28162770	PL21	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.07708121808498203	[317]	[145]	0	hSpCas9	negative selection	10860272
23904033	23904056	18	+	28162770	PL21	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-1.0477878989542653	[37]	[7]	-6	hSpCas9	negative selection	10860273
23881935	23881958	18	+	28162770	P31FUJ	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.2251211077176417	[173]	[238]	2	hSpCas9	negative selection	11029630
23904551	23904574	18	+	28162770	P31FUJ	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.017642160829208144	[210]	[250]	0	hSpCas9	negative selection	11029631
23904606	23904629	18	-	28162770	P31FUJ	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.4207473815641901	[266]	[419]	5	hSpCas9	negative selection	11029632
23916641	23916664	18	+	28162770	P31FUJ	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.6005479261761699	[54]	[97]	7	hSpCas9	negative selection	11029633
23882004	23882027	18	-	28162770	P31FUJ	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	0.8021315856950084	[203]	[417]	8	hSpCas9	negative selection	11029634
23894965	23894988	18	-	28162770	P31FUJ	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	0.9172232395902289	[72]	[161]	9	hSpCas9	negative selection	11029635
23895028	23895051	18	+	28162770	P31FUJ	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.8922930155671542	[413]	[902]	8	hSpCas9	negative selection	11029636
23903061	23903084	18	-	28162770	P31FUJ	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.2338403291180162	[253]	[350]	2	hSpCas9	negative selection	11029637
23904013	23904036	18	+	28162770	P31FUJ	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.031471398605760315	[413]	[475]	0	hSpCas9	negative selection	11029638
23904033	23904056	18	+	28162770	P31FUJ	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-0.8457790813051314	[51]	[33]	-6	hSpCas9	negative selection	11029639
23881935	23881958	18	+	28162770	OCIAML5	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.3519473211575964	[78]	[181]	3	hSpCas9	negative selection	11198996
23904551	23904574	18	+	28162770	OCIAML5	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.5819200312158369	[103]	[280]	5	hSpCas9	negative selection	11198997
23904606	23904629	18	-	28162770	OCIAML5	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	-0.2118542095773785	[110]	[172]	-1	hSpCas9	negative selection	11198998
23916641	23916664	18	+	28162770	OCIAML5	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	-2.7780659894202198	[18]	[4]	-8	hSpCas9	negative selection	11198999
23882004	23882027	18	-	28162770	OCIAML5	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.10229320039717066	[156]	[263]	0	hSpCas9	negative selection	11199000
23894965	23894988	18	-	28162770	OCIAML5	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	1.5828704858525517	[26]	[145]	9	hSpCas9	negative selection	11199001
23895028	23895051	18	+	28162770	OCIAML5	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.23853597791690961	[215]	[459]	2	hSpCas9	negative selection	11199002
23903061	23903084	18	-	28162770	OCIAML5	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.3309382576223051	[121]	[276]	3	hSpCas9	negative selection	11199003
23904013	23904036	18	+	28162770	OCIAML5	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.1376528186876389	[244]	[401]	-1	hSpCas9	negative selection	11199004
23904033	23904056	18	+	28162770	OCIAML5	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.7499694432161004	[27]	[84]	6	hSpCas9	negative selection	11199005
23881935	23881958	18	+	28162770	EOL1	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.30305939482426436	[279]	[181]	2	hSpCas9	negative selection	11368362
23904551	23904574	18	+	28162770	EOL1	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	-0.7740715109461888	[197]	[60]	-5	hSpCas9	negative selection	11368363
23904606	23904629	18	-	28162770	EOL1	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	-1.066555827941069	[484]	[121]	-6	hSpCas9	negative selection	11368364
23916641	23916664	18	+	28162770	EOL1	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	-0.712882149044757	[83]	[26]	-5	hSpCas9	negative selection	11368365
23882004	23882027	18	-	28162770	EOL1	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.27738054720619776	[489]	[212]	-2	hSpCas9	negative selection	11368366
23894965	23894988	18	-	28162770	EOL1	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	0.11010342472661105	[101]	[57]	1	hSpCas9	negative selection	11368367
23895028	23895051	18	+	28162770	EOL1	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	-0.08645122737872257	[394]	[195]	0	hSpCas9	negative selection	11368368
23903061	23903084	18	-	28162770	EOL1	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.39021134391934637	[251]	[173]	3	hSpCas9	negative selection	11368369
23904013	23904036	18	+	28162770	EOL1	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.22074904133952777	[429]	[263]	2	hSpCas9	negative selection	11368370
23904033	23904056	18	+	28162770	EOL1	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-1.0389263524043515	[38]	[9]	-6	hSpCas9	negative selection	11368371
23881935	23881958	18	+	28162770	MOLM13	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-1.2373673528942892	[299]	[91]	-6	hSpCas9	negative selection	11537728
23904551	23904574	18	+	28162770	MOLM13	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.010038798726761888	[227]	[165]	0	hSpCas9	negative selection	11537729
23904606	23904629	18	-	28162770	MOLM13	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	-0.6831184065551035	[321]	[144]	-4	hSpCas9	negative selection	11537730
23916641	23916664	18	+	28162770	MOLM13	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	2.927321000181876	[63]	[351]	9	hSpCas9	negative selection	11537731
23882004	23882027	18	-	28162770	MOLM13	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	0.28833996121386635	[281]	[248]	2	hSpCas9	negative selection	11537732
23894965	23894988	18	-	28162770	MOLM13	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	2.0800733510007596	[69]	[213]	9	hSpCas9	negative selection	11537733
23895028	23895051	18	+	28162770	MOLM13	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.8182385155911723	[381]	[486]	6	hSpCas9	negative selection	11537734
23903061	23903084	18	-	28162770	MOLM13	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.5609987859360605	[254]	[271]	4	hSpCas9	negative selection	11537735
23904013	23904036	18	+	28162770	MOLM13	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.7931835079559287	[440]	[183]	-4	hSpCas9	negative selection	11537736
23904033	23904056	18	+	28162770	MOLM13	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.735369692409565	[53]	[64]	5	hSpCas9	negative selection	11537737
23881935	23881958	18	+	28162770	HEL	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.00022927215636470155	[202]	[129]	0	hSpCas9	negative selection	11707094
23904551	23904574	18	+	28162770	HEL	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	1.096914725186159	[199]	[273]	8	hSpCas9	negative selection	11707095
23904606	23904629	18	-	28162770	HEL	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.5344062102122836	[234]	[217]	4	hSpCas9	negative selection	11707096
23916641	23916664	18	+	28162770	HEL	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	2.250421409221597	[41]	[127]	9	hSpCas9	negative selection	11707097
23882004	23882027	18	-	28162770	HEL	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	0.7729952179516985	[253]	[277]	6	hSpCas9	negative selection	11707098
23894965	23894988	18	-	28162770	HEL	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	-0.22893707102410343	[85]	[46]	-2	hSpCas9	negative selection	11707099
23895028	23895051	18	+	28162770	HEL	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.4691752534946966	[396]	[351]	4	hSpCas9	negative selection	11707100
23903061	23903084	18	-	28162770	HEL	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	-0.37863481879221006	[271]	[133]	-3	hSpCas9	negative selection	11707101
23904013	23904036	18	+	28162770	HEL	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.063445081365893	[380]	[254]	0	hSpCas9	negative selection	11707102
23904033	23904056	18	+	28162770	HEL	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.36263091280762194	[50]	[41]	3	hSpCas9	negative selection	11707103
23881935	23881958	18	+	28162770	MV411	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.6632951111201373	[140]	[74]	-5	hSpCas9	negative selection	11876460
23904551	23904574	18	+	28162770	MV411	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.9110743656318441	[112]	[178]	7	hSpCas9	negative selection	11876461
23904606	23904629	18	-	28162770	MV411	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	-0.11843389169218399	[249]	[193]	-1	hSpCas9	negative selection	11876462
23916641	23916664	18	+	28162770	MV411	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	1.0734081510077265	[21]	[38]	8	hSpCas9	negative selection	11876463
23882004	23882027	18	-	28162770	MV411	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	0.7779522674815551	[233]	[337]	7	hSpCas9	negative selection	11876464
23894965	23894988	18	-	28162770	MV411	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	-0.7318038890504273	[68]	[34]	-5	hSpCas9	negative selection	11876465
23895028	23895051	18	+	28162770	MV411	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	1.1614236350744207	[310]	[585]	8	hSpCas9	negative selection	11876466
23903061	23903084	18	-	28162770	MV411	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.30663334329067543	[190]	[198]	2	hSpCas9	negative selection	11876467
23904013	23904036	18	+	28162770	MV411	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.49514711588459104	[342]	[204]	-4	hSpCas9	negative selection	11876468
23904033	23904056	18	+	28162770	MV411	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	-0.25213345870773596	[40]	[28]	-2	hSpCas9	negative selection	11876469
23881935	23881958	18	+	28162770	MONOMAC1	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.3875587531089796	[96]	[84]	-3	hSpCas9	negative selection	12045826
23904551	23904574	18	+	28162770	MONOMAC1	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	-0.22049581988354247	[123]	[121]	-2	hSpCas9	negative selection	12045827
23904606	23904629	18	-	28162770	MONOMAC1	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	1.8002487682434105	[132]	[530]	9	hSpCas9	negative selection	12045828
23916641	23916664	18	+	28162770	MONOMAC1	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	-0.4421493448960854	[31]	[26]	-4	hSpCas9	negative selection	12045829
23882004	23882027	18	-	28162770	MONOMAC1	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	1.032325129091736	[176]	[414]	8	hSpCas9	negative selection	12045830
23894965	23894988	18	-	28162770	MONOMAC1	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	-1.3247923942579265	[58]	[26]	-7	hSpCas9	negative selection	12045831
23895028	23895051	18	+	28162770	MONOMAC1	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.4622578510224557	[144]	[228]	4	hSpCas9	negative selection	12045832
23903061	23903084	18	-	28162770	MONOMAC1	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	0.1331117546327772	[104]	[131]	1	hSpCas9	negative selection	12045833
23904013	23904036	18	+	28162770	MONOMAC1	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	0.3902695941299016	[204]	[307]	4	hSpCas9	negative selection	12045834
23904033	23904056	18	+	28162770	MONOMAC1	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.03244499906321341	[28]	[33]	0	hSpCas9	negative selection	12045835
23881935	23881958	18	+	28162770	OCIAML2	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	0.22026612022806014	[34]	[225]	2	hSpCas9	negative selection	12215192
23904551	23904574	18	+	28162770	OCIAML2	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	-0.12148026161977443	[20]	[106]	-1	hSpCas9	negative selection	12215193
23904606	23904629	18	-	28162770	OCIAML2	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	0.181446871337532	[41]	[263]	1	hSpCas9	negative selection	12215194
23916641	23916664	18	+	28162770	OCIAML2	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	0.5293701747578387	[12]	[103]	5	hSpCas9	negative selection	12215195
23882004	23882027	18	-	28162770	OCIAML2	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.08777273171246708	[50]	[265]	0	hSpCas9	negative selection	12215196
23894965	23894988	18	-	28162770	OCIAML2	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	0.11433267547899506	[11]	[71]	1	hSpCas9	negative selection	12215197
23895028	23895051	18	+	28162770	OCIAML2	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.5293701747578387	[53]	[431]	5	hSpCas9	negative selection	12215198
23903061	23903084	18	-	28162770	OCIAML2	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	-0.37259774228163445	[31]	[136]	-3	hSpCas9	negative selection	12215199
23904013	23904036	18	+	28162770	OCIAML2	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.2660586809929577	[63]	[294]	-2	hSpCas9	negative selection	12215200
23904033	23904056	18	+	28162770	OCIAML2	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.24557720875724742	[6]	[45]	2	hSpCas9	negative selection	12215201
23881935	23881958	18	+	28162770	OCIAML3	viability	GAACTGTCAGCACAACACCGCGG	LAMA3	ENSG00000053747	-0.1124747292584125	[52]	[147]	-1	hSpCas9	negative selection	12384558
23904551	23904574	18	+	28162770	OCIAML3	viability	AGGATCAAGAGAAACGCCAGCGG	LAMA3	ENSG00000053747	0.46332553474178856	[36]	[153]	4	hSpCas9	negative selection	12384559
23904606	23904629	18	-	28162770	OCIAML3	viability	GAGGATGTTCTCGTAGGCGGTGG	LAMA3	ENSG00000053747	-1.0011830218300366	[60]	[91]	-6	hSpCas9	negative selection	12384560
23916641	23916664	18	+	28162770	OCIAML3	viability	ACAGACAATTCAGACCACCGTGG	LAMA3	ENSG00000053747	-1.146548663352942	[21]	[29]	-7	hSpCas9	negative selection	12384561
23882004	23882027	18	-	28162770	OCIAML3	viability	GGCAGGCCCTGCAGGATCCGTGG	LAMA3	ENSG00000053747	-0.24390887274563966	[70]	[180]	-2	hSpCas9	negative selection	12384562
23894965	23894988	18	-	28162770	OCIAML3	viability	GCAGCTGAGACTTGACCAGGCGG	LAMA3	ENSG00000053747	-1.4364663633376833	[25]	[28]	-7	hSpCas9	negative selection	12384563
23895028	23895051	18	+	28162770	OCIAML3	viability	GCACATGGAGACCCAGGCCAAGG	LAMA3	ENSG00000053747	0.35652368341153684	[88]	[343]	3	hSpCas9	negative selection	12384564
23903061	23903084	18	-	28162770	OCIAML3	viability	CAACAAAGATGAGTCTGCAGTGG	LAMA3	ENSG00000053747	-0.26620297910013146	[48]	[122]	-2	hSpCas9	negative selection	12384565
23904013	23904036	18	+	28162770	OCIAML3	viability	TGGCAAAACATCCCTTGTGGAGG	LAMA3	ENSG00000053747	-0.03542055502730446	[91]	[270]	0	hSpCas9	negative selection	12384566
23904033	23904056	18	+	28162770	OCIAML3	viability	AGGAGGCAGAAAAGCACGCGCGG	LAMA3	ENSG00000053747	0.05806905625553016	[6]	[21]	0	hSpCas9	negative selection	12384567