Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:3949
• Symbol:LDLR
• Description:low density lipoprotein receptor

DataSource: http://genomecrispr.dkfz.de/#!/results/LDLR

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
11110660	11110683	19	+	26472758	Jiyoye	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.053901049751166386	[220]	[172]	0	hSpCas9	negative selection	89639
11123207	11123230	19	-	26472758	Jiyoye	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	0.45346903377980835	[91]	[94]	3	hSpCas9	negative selection	89640
11113281	11113304	19	-	26472758	Jiyoye	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	1.1639042304935097	[28]	[48]	7	hSpCas9	negative selection	89641
11089540	11089563	19	+	26472758	Jiyoye	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	2.3214455074799893	[38]	[146]	9	hSpCas9	negative selection	89642
11089556	11089579	19	+	26472758	Jiyoye	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	1.85127534638718	[42]	[116]	8	hSpCas9	negative selection	89643
11110750	11110773	19	+	26472758	Jiyoye	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.07089199364144094	[201]	[159]	0	hSpCas9	negative selection	89644
11111548	11111571	19	+	26472758	Jiyoye	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	0.1885350950305329	[63]	[54]	1	hSpCas9	negative selection	89645
11113350	11113373	19	+	26472758	Jiyoye	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	0.03975590245976934	[297]	[230]	0	hSpCas9	negative selection	89646
11113378	11113401	19	+	26472758	Jiyoye	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.34618465091100115	[58]	[34]	-2	hSpCas9	negative selection	89647
11113738	11113761	19	-	26472758	Jiyoye	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-1.2749282776258144	[214]	[66]	-7	hSpCas9	negative selection	89648
11110660	11110683	19	+	26472758	KBM7	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.3024351575119313	[969,797]	[281,382]	-3	hSpCas9	negative selection	280757
11123207	11123230	19	-	26472758	KBM7	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.756140221815031	[677,729]	[165,225]	-6	hSpCas9	negative selection	280758
11113281	11113304	19	-	26472758	KBM7	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	0.47552879062580355	[256,206]	[183,120]	5	hSpCas9	negative selection	280759
11089540	11089563	19	+	26472758	KBM7	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.3498395024326686	[556,394]	[410,165]	4	hSpCas9	negative selection	280760
11089556	11089579	19	+	26472758	KBM7	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.4465966271338295	[263,154]	[77,178]	5	hSpCas9	negative selection	280761
11110750	11110773	19	+	26472758	KBM7	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.13309271282308355	[996,613]	[543,284]	1	hSpCas9	negative selection	280762
11111548	11111571	19	+	26472758	KBM7	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	0.4231271135535233	[253,153]	[172,83]	4	hSpCas9	negative selection	280763
11113350	11113373	19	+	26472758	KBM7	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	0.25497931634815596	[1168,1188]	[583,737]	2	hSpCas9	negative selection	280764
11113378	11113401	19	+	26472758	KBM7	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	0.15685345876507217	[401,307]	[184,183]	1	hSpCas9	negative selection	280765
11113738	11113761	19	-	26472758	KBM7	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.44589903007247206	[508,599]	[213,175]	-4	hSpCas9	negative selection	280766
11110660	11110683	19	+	26472758	Raji	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.4707589148299506	[397]	[127]	4	hSpCas9	negative selection	471875
11123207	11123230	19	-	26472758	Raji	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.17272438381913577	[305]	[62]	-1	hSpCas9	negative selection	471876
11113281	11113304	19	-	26472758	Raji	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.01914887055533243	[130]	[29]	0	hSpCas9	negative selection	471877
11089540	11089563	19	+	26472758	Raji	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.5094819789449452	[223]	[73]	5	hSpCas9	negative selection	471878
11089556	11089579	19	+	26472758	Raji	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	-0.14357803815961923	[118]	[24]	-1	hSpCas9	negative selection	471879
11110750	11110773	19	+	26472758	Raji	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	1.0479506218544417	[222]	[106]	8	hSpCas9	negative selection	471880
11111548	11111571	19	+	26472758	Raji	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	0.13775718441711837	[93]	[23]	1	hSpCas9	negative selection	471881
11113350	11113373	19	+	26472758	Raji	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.684029842814983	[719]	[103]	-5	hSpCas9	negative selection	471882
11113378	11113401	19	+	26472758	Raji	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	0.45530683879390643	[153]	[48]	4	hSpCas9	negative selection	471883
11113738	11113761	19	-	26472758	Raji	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.6475039667898691	[269]	[39]	-5	hSpCas9	negative selection	471884
11110660	11110683	19	+	26472758	K562	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.5634449918010822	[708]	[404]	-4	hSpCas9	negative selection	662993
11123207	11123230	19	-	26472758	K562	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.11093786148568702	[512]	[400]	-1	hSpCas9	negative selection	662994
11113281	11113304	19	-	26472758	K562	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-1.2351315331671255	[342]	[122]	-6	hSpCas9	negative selection	662995
11089540	11089563	19	+	26472758	K562	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.937440974245056	[299]	[484]	7	hSpCas9	negative selection	662996
11089556	11089579	19	+	26472758	K562	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	-0.1310904074257595	[191]	[147]	-1	hSpCas9	negative selection	662997
11110750	11110773	19	+	26472758	K562	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.9235427988941944	[513]	[822]	7	hSpCas9	negative selection	662998
11111548	11111571	19	+	26472758	K562	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	0.3289522378781147	[115]	[122]	2	hSpCas9	negative selection	662999
11113350	11113373	19	+	26472758	K562	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.47449413825425846	[952]	[578]	-3	hSpCas9	negative selection	663000
11113378	11113401	19	+	26472758	K562	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.23225783740478279	[262]	[188]	-1	hSpCas9	negative selection	663001
11113738	11113761	19	-	26472758	K562	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	0.0051277817566305894	[457]	[387]	0	hSpCas9	negative selection	663002
11100265	11100288	19	+	26627737	DLD1	viability	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.2337123345896283	[522]	[207,361,37]	2	hSpCas9	negative selection	802445
11102704	11102727	19	-	26627737	DLD1	viability	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.004018820474462892	[215]	[72,27,95]	0	hSpCas9	negative selection	802446
11105280	11105303	19	+	26627737	DLD1	viability	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.20094399197539692	[271]	[75,101,48]	-2	hSpCas9	negative selection	802447
11106574	11106597	19	-	26627737	DLD1	viability	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.45842585795906987	[988]	[359,658,286]	5	hSpCas9	negative selection	802448
11107385	11107408	19	+	26627737	DLD1	viability	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.7647365564674915	[1653]	[299,377,246]	-6	hSpCas9	negative selection	802449
11110660	11110683	19	+	26627737	DLD1	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.20255797639171705	[487]	[226,102,190]	2	hSpCas9	negative selection	802450
11100265	11100288	19	+	26627737	GBM cells	viability after 5 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.14749022802578837	[350]	[188,227]	2	hSpCas9	negative selection	884760
11102704	11102727	19	-	26627737	GBM cells	viability after 5 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.009945187274429612	[124]	[39,94]	0	hSpCas9	negative selection	884761
11105280	11105303	19	+	26627737	GBM cells	viability after 5 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.13262169854742123	[184]	[89,90]	-2	hSpCas9	negative selection	884762
11106574	11106597	19	-	26627737	GBM cells	viability after 5 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.5162687341227026	[366]	[251,310]	7	hSpCas9	negative selection	884763
11107385	11107408	19	+	26627737	GBM cells	viability after 5 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.4577198980003998	[588]	[237,221]	-6	hSpCas9	negative selection	884764
11110660	11110683	19	+	26627737	GBM cells	viability after 5 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.0574968565666316	[325]	[72,94]	-9	hSpCas9	negative selection	884765
11100265	11100288	19	+	26627737	GBM cells	viability after 13 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.06077409578932502	[350]	[186,178]	0	hSpCas9	negative selection	967075
11102704	11102727	19	-	26627737	GBM cells	viability after 13 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.24022190520871067	[124]	[68,47]	-3	hSpCas9	negative selection	967076
11105280	11105303	19	+	26627737	GBM cells	viability after 13 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.05177345304432729	[184]	[119,77]	0	hSpCas9	negative selection	967077
11106574	11106597	19	-	26627737	GBM cells	viability after 13 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.7632207624808662	[366]	[273,389]	8	hSpCas9	negative selection	967078
11107385	11107408	19	+	26627737	GBM cells	viability after 13 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.6137278429080615	[588]	[172,237]	-6	hSpCas9	negative selection	967079
11110660	11110683	19	+	26627737	GBM cells	viability after 13 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.3684380939334735	[325]	[46,85]	-8	hSpCas9	negative selection	967080
11100265	11100288	19	+	26627737	GBM cells	viability after 21 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.3338257433595274	[350]	[155,146]	-3	hSpCas9	negative selection	1049390
11102704	11102727	19	-	26627737	GBM cells	viability after 21 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.7549122488231139	[124]	[123,105]	7	hSpCas9	negative selection	1049391
11105280	11105303	19	+	26627737	GBM cells	viability after 21 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.07220944780726757	[184]	[104,86]	0	hSpCas9	negative selection	1049392
11106574	11106597	19	-	26627737	GBM cells	viability after 21 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.347892644597542	[366]	[282,226]	3	hSpCas9	negative selection	1049393
11107385	11107408	19	+	26627737	GBM cells	viability after 21 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.7701181869555036	[588]	[207,168]	-6	hSpCas9	negative selection	1049394
11110660	11110683	19	+	26627737	GBM cells	viability after 21 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.157831585823871	[325]	[93,65]	-7	hSpCas9	negative selection	1049395
11100265	11100288	19	+	26627737	RPE1	viability after 9 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.64934184866134	[895]	[101,277]	-5	hSpCas9	negative selection	1131705
11102704	11102727	19	-	26627737	RPE1	viability after 9 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.6684399138125885	[965]	[112,289]	-5	hSpCas9	negative selection	1131706
11105280	11105303	19	+	26627737	RPE1	viability after 9 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.9640180422942367	[412]	[239,267]	6	hSpCas9	negative selection	1131707
11106574	11106597	19	-	26627737	RPE1	viability after 9 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.5717190289557004	[1343]	[596,661]	4	hSpCas9	negative selection	1131708
11107385	11107408	19	+	26627737	RPE1	viability after 9 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.18454022550257165	[884]	[313,315]	1	hSpCas9	negative selection	1131709
11110660	11110683	19	+	26627737	RPE1	viability after 9 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.8348062925062338	[1271]	[115,105]	-8	hSpCas9	negative selection	1131710
11100265	11100288	19	+	26627737	RPE1	viability after 12 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.1262642233887471	[895]	[321,199]	0	hSpCas9	negative selection	1214020
11102704	11102727	19	-	26627737	RPE1	viability after 12 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.8288145388659529	[965]	[47,249]	-5	hSpCas9	negative selection	1214021
11105280	11105303	19	+	26627737	RPE1	viability after 12 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	1.032117068833194	[412]	[206,247]	6	hSpCas9	negative selection	1214022
11106574	11106597	19	-	26627737	RPE1	viability after 12 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.5955693706467833	[1343]	[549,540]	4	hSpCas9	negative selection	1214023
11107385	11107408	19	+	26627737	RPE1	viability after 12 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.0482906604366615	[884]	[227,231]	0	hSpCas9	negative selection	1214024
11110660	11110683	19	+	26627737	RPE1	viability after 12 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.5655579243727245	[1271]	[113,116]	-8	hSpCas9	negative selection	1214025
11100265	11100288	19	+	26627737	RPE1	viability after 15 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.5892742559816144	[895]	[362,398]	4	hSpCas9	negative selection	1296335
11102704	11102727	19	-	26627737	RPE1	viability after 15 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.5928967264167797	[965]	[86,271]	-4	hSpCas9	negative selection	1296336
11105280	11105303	19	+	26627737	RPE1	viability after 15 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.7239034916059139	[412]	[138,244]	4	hSpCas9	negative selection	1296337
11106574	11106597	19	-	26627737	RPE1	viability after 15 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.7440121323372317	[1343]	[453,812]	4	hSpCas9	negative selection	1296338
11107385	11107408	19	+	26627737	RPE1	viability after 15 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.0726475304719188	[884]	[303,223]	0	hSpCas9	negative selection	1296339
11110660	11110683	19	+	26627737	RPE1	viability after 15 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.865557457710074	[1271]	[310,87]	-5	hSpCas9	negative selection	1296340
11100265	11100288	19	+	26627737	RPE1	viability after 18 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.05856185383532819	[895]	[333,163]	0	hSpCas9	negative selection	1378650
11102704	11102727	19	-	26627737	RPE1	viability after 18 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.8119150197248695	[965]	[60,241]	-5	hSpCas9	negative selection	1378651
11105280	11105303	19	+	26627737	RPE1	viability after 18 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.9759863708228507	[412]	[225,211]	6	hSpCas9	negative selection	1378652
11106574	11106597	19	-	26627737	RPE1	viability after 18 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.7987928520696232	[1343]	[571,693]	5	hSpCas9	negative selection	1378653
11107385	11107408	19	+	26627737	RPE1	viability after 18 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.037693218549283036	[884]	[307,177]	0	hSpCas9	negative selection	1378654
11110660	11110683	19	+	26627737	RPE1	viability after 18 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.590384659609974	[1271]	[142,82]	-7	hSpCas9	negative selection	1378655
11100265	11100288	19	+	26627737	HeLa	viability after 8 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.6533762173042517	[976]	[364,170,293]	-6	hSpCas9	negative selection	1460965
11102704	11102727	19	-	26627737	HeLa	viability after 8 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-1.0606776338031891	[311]	[93,62,45]	-8	hSpCas9	negative selection	1460966
11105280	11105303	19	+	26627737	HeLa	viability after 8 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-1.607588323427813	[438]	[69,61,57]	-9	hSpCas9	negative selection	1460967
11106574	11106597	19	-	26627737	HeLa	viability after 8 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.3219813368379414	[806]	[438,499,381]	3	hSpCas9	negative selection	1460968
11107385	11107408	19	+	26627737	HeLa	viability after 8 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.14719394254500584	[587]	[340,212,306]	1	hSpCas9	negative selection	1460969
11110660	11110683	19	+	26627737	HeLa	viability after 8 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.4544708878575807	[486]	[218,176,86]	-4	hSpCas9	negative selection	1460970
11100265	11100288	19	+	26627737	HeLa	viability after 12 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.16995863815330048	[976]	[425,326,328]	-1	hSpCas9	negative selection	1543280
11102704	11102727	19	-	26627737	HeLa	viability after 12 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.16350220735965093	[311]	[219,72,149]	1	hSpCas9	negative selection	1543281
11105280	11105303	19	+	26627737	HeLa	viability after 12 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.8904460317162577	[438]	[146,50,101]	-7	hSpCas9	negative selection	1543282
11106574	11106597	19	-	26627737	HeLa	viability after 12 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.2194645595957181	[806]	[426,397,339]	2	hSpCas9	negative selection	1543283
11107385	11107408	19	+	26627737	HeLa	viability after 12 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.001224806210808782	[587]	[254,211,264]	0	hSpCas9	negative selection	1543284
11110660	11110683	19	+	26627737	HeLa	viability after 12 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.6176802423728356	[486]	[100,136,153]	-5	hSpCas9	negative selection	1543285
11100265	11100288	19	+	26627737	HeLa	viability after 15 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.4900387501470459	[976]	[429,178,234]	-4	hSpCas9	negative selection	1625595
11102704	11102727	19	-	26627737	HeLa	viability after 15 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.8347993010630849	[311]	[77,70,63]	-6	hSpCas9	negative selection	1625596
11105280	11105303	19	+	26627737	HeLa	viability after 15 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.6189580308196831	[438]	[188,56,100]	-5	hSpCas9	negative selection	1625597
11106574	11106597	19	-	26627737	HeLa	viability after 15 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.7391401392559882	[806]	[354,763,526]	6	hSpCas9	negative selection	1625598
11107385	11107408	19	+	26627737	HeLa	viability after 15 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.49068430372596317	[587]	[429,299,272]	4	hSpCas9	negative selection	1625599
11110660	11110683	19	+	26627737	HeLa	viability after 15 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.603144195957409	[486]	[65,109,15]	-8	hSpCas9	negative selection	1625600
11100265	11100288	19	+	26627737	HeLa	viability after 18 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.4923699252937359	[976]	[290,143,234]	-4	hSpCas9	negative selection	1707910
11102704	11102727	19	-	26627737	HeLa	viability after 18 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.7994836873793142	[311]	[53,60,63]	-6	hSpCas9	negative selection	1707911
11105280	11105303	19	+	26627737	HeLa	viability after 18 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.6919721337013072	[438]	[118,42,100]	-6	hSpCas9	negative selection	1707912
11106574	11106597	19	-	26627737	HeLa	viability after 18 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.7508823987044531	[806]	[244,634,526]	6	hSpCas9	negative selection	1707913
11107385	11107408	19	+	26627737	HeLa	viability after 18 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.4772986505893657	[587]	[285,243,272]	4	hSpCas9	negative selection	1707914
11110660	11110683	19	+	26627737	HeLa	viability after 18 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.5359735472919769	[486]	[43,98,15]	-8	hSpCas9	negative selection	1707915
11100265	11100288	19	+	26627737	HCT116	viability after 6 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.43460875837455504	[1027]	[492,66]	2	hSpCas9	negative selection	1790225
11102704	11102727	19	-	26627737	HCT116	viability after 6 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.2977826664388873	[642]	[20,115]	-2	hSpCas9	negative selection	1790226
11105280	11105303	19	+	26627737	HCT116	viability after 6 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.40009914266906016	[583]	[95,54]	-2	hSpCas9	negative selection	1790227
11106574	11106597	19	-	26627737	HCT116	viability after 6 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.9239034345506151	[908]	[89,370]	5	hSpCas9	negative selection	1790228
11107385	11107408	19	+	26627737	HCT116	viability after 6 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	1.804926114679025	[879]	[581,428]	8	hSpCas9	negative selection	1790229
11110660	11110683	19	+	26627737	HCT116	viability after 6 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.09445856545740647	[583]	[143,53]	0	hSpCas9	negative selection	1790230
11100265	11100288	19	+	26627737	HCT116	viability after 8 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.5491768719663839	[270]	[253,253,148]	5	hSpCas9	negative selection	1872540
11102704	11102727	19	-	26627737	HCT116	viability after 8 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.4478482409219	[141]	[106,90,121]	5	hSpCas9	negative selection	1872541
11105280	11105303	19	+	26627737	HCT116	viability after 8 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.6054654017408989	[127]	[139,114,67]	6	hSpCas9	negative selection	1872542
11106574	11106597	19	-	26627737	HCT116	viability after 8 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.1847431433452974	[667]	[320,286,362]	-2	hSpCas9	negative selection	1872543
11107385	11107408	19	+	26627737	HCT116	viability after 8 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	1.0626285175856591	[217]	[265,236,249]	8	hSpCas9	negative selection	1872544
11110660	11110683	19	+	26627737	HCT116	viability after 8 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.7121678613683612	[422]	[155,122,147]	-7	hSpCas9	negative selection	1872545
11100265	11100288	19	+	26627737	HCT116	viability after 9 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-1.2844871002654752	[1027]	[191,49]	-7	hSpCas9	negative selection	1954855
11102704	11102727	19	-	26627737	HCT116	viability after 9 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-1.2602734214908407	[642]	[69,72]	-7	hSpCas9	negative selection	1954856
11105280	11105303	19	+	26627737	HCT116	viability after 9 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-1.4043963059300353	[583]	[54,61]	-7	hSpCas9	negative selection	1954857
11106574	11106597	19	-	26627737	HCT116	viability after 9 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.03166399003237308	[908]	[318,172]	0	hSpCas9	negative selection	1954858
11107385	11107408	19	+	26627737	HCT116	viability after 9 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.7482856144801863	[879]	[592,237]	5	hSpCas9	negative selection	1954859
11110660	11110683	19	+	26627737	HCT116	viability after 9 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.18049264981412672	[583]	[83,249]	1	hSpCas9	negative selection	1954860
11100265	11100288	19	+	26627737	HCT116	viability after 12 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.6533429968231138	[270]	[178,308,189]	6	hSpCas9	negative selection	2037170
11102704	11102727	19	-	26627737	HCT116	viability after 12 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.5839575092302514	[141]	[66,172,100]	5	hSpCas9	negative selection	2037171
11105280	11105303	19	+	26627737	HCT116	viability after 12 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	1.3589323614354853	[127]	[205,185,122]	9	hSpCas9	negative selection	2037172
11106574	11106597	19	-	26627737	HCT116	viability after 12 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.388331391831786	[667]	[255,321,228]	-4	hSpCas9	negative selection	2037173
11107385	11107408	19	+	26627737	HCT116	viability after 12 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	1.181873896312507	[217]	[220,211,348]	8	hSpCas9	negative selection	2037174
11110660	11110683	19	+	26627737	HCT116	viability after 12 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.06899702397260077	[422]	[201,261,238]	0	hSpCas9	negative selection	2037175
11100265	11100288	19	+	26627737	HCT116	viability after 15 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.6936767679848902	[270]	[259,312,183]	6	hSpCas9	negative selection	2119485
11102704	11102727	19	-	26627737	HCT116	viability after 15 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.6706782960981033	[141]	[64,223,92]	6	hSpCas9	negative selection	2119486
11105280	11105303	19	+	26627737	HCT116	viability after 15 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.9605440685213542	[127]	[170,154,106]	7	hSpCas9	negative selection	2119487
11106574	11106597	19	-	26627737	HCT116	viability after 15 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.4872407937381782	[667]	[475,207,162]	-5	hSpCas9	negative selection	2119488
11107385	11107408	19	+	26627737	HCT116	viability after 15 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	1.2382544839421814	[217]	[291,326,266]	8	hSpCas9	negative selection	2119489
11110660	11110683	19	+	26627737	HCT116	viability after 15 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.07932432953033763	[422]	[157,206,314]	-1	hSpCas9	negative selection	2119490
11100265	11100288	19	+	26627737	HCT116	viability after 18 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	1.040374425096439	[270]	[224,333,243]	7	hSpCas9	negative selection	2201800
11102704	11102727	19	-	26627737	HCT116	viability after 18 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.9183203198152714	[141]	[51,214,115]	7	hSpCas9	negative selection	2201801
11105280	11105303	19	+	26627737	HCT116	viability after 18 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	1.020578455791273	[127]	[80,191,97]	7	hSpCas9	negative selection	2201802
11106574	11106597	19	-	26627737	HCT116	viability after 18 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.13002663203995768	[667]	[442,262,175]	-1	hSpCas9	negative selection	2201803
11107385	11107408	19	+	26627737	HCT116	viability after 18 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	1.4618785398391818	[217]	[313,305,247]	9	hSpCas9	negative selection	2201804
11110660	11110683	19	+	26627737	HCT116	viability after 18 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.743576322422368	[422]	[331,433,250]	6	hSpCas9	negative selection	2201805
11114744	11114767	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCCGAGGCGGGTGGATCACAGGG	LDLR	ENSG00000130164	2.1502832554388824	[230,177]	[276,116]	7	dCas9-VP64	positive selection	2400421
11115781	11115804	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCGCCCACCACCACGCCTGG	LDLR	ENSG00000130164	1.906510521561382	[74,11]	[56,10]	6	dCas9-VP64	positive selection	2400703
11126962	11126985	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	GAAGTCTTGCTCTGTTGCCCCAG	LDLR	ENSG00000130164	-0.819451643023694	[60,30]	[3,6]	-4	dCas9-VP64	positive selection	2435820
11117863	11117886	19	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGGAGGATCACTTGAGGCCGGG	LDLR	ENSG00000130164	3.7396651611807004	[3,72]	[11,226]	9	dCas9-VP64	positive selection	2451783
11122135	11122158	19	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCGCCCAGGCTGGAGTGCAGCGG	LDLR	ENSG00000130164	0.5070772209909733	[97,61]	[39,7]	2	dCas9-VP64	positive selection	2477683
11114744	11114767	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCCGAGGCGGGTGGATCACAGGG	LDLR	ENSG00000130164	0.9222606626235144	[35,66]	[18,42]	6	dCas9-VP64	positive selection	2495676
11115781	11115804	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCGCCCACCACCACGCCTGG	LDLR	ENSG00000130164	1.1664475786686166	[321,97]	[88,216]	7	dCas9-VP64	positive selection	2495958
11126962	11126985	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	GAAGTCTTGCTCTGTTGCCCCAG	LDLR	ENSG00000130164	-0.47354638593983023	[115,143]	[24,34]	-5	dCas9-VP64	positive selection	2531075
11117863	11117886	19	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGGAGGATCACTTGAGGCCGGG	LDLR	ENSG00000130164	0.5989374680558959	[87,40]	[52,11]	4	dCas9-VP64	positive selection	2547038
11122135	11122158	19	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCGCCCAGGCTGGAGTGCAGCGG	LDLR	ENSG00000130164	-0.06949214303462026	[365,454]	[80,170]	0	dCas9-VP64	positive selection	2572938
11107446	11107469	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATGTTGCAGACTTTGTCCAGGG	LDLR	ENSG00000130164	-0.4521654743901478	[3,3]	[1,2]	-6	hSpCas9	positive selection	2999154
11110661	11110684	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.2724241374187752	[3,3]	[3,3]	6	hSpCas9	positive selection	2999155
11102713	11102736	19	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCCAGAACTGAGGAATGCAGCGG	LDLR	ENSG00000130164	-0.8262865971333062	[3,2]	[2,0]	-8	hSpCas9	positive selection	2999156
11107385	11107408	19	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTCACAGTGACACTCTGCGAGG	LDLR	ENSG00000130164	-0.06061312531559926	[1,0]	[1,0]	-1	hSpCas9	positive selection	2999157
11107446	11107469	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATGTTGCAGACTTTGTCCAGGG	LDLR	ENSG00000130164	-0.42307411184958355	[3,3]	[3,0]	-6	hSpCas9	positive selection	3067012
11110661	11110684	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.014070647939473716	[3,3]	[3,1]	0	hSpCas9	positive selection	3067013
11102713	11102736	19	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCCAGAACTGAGGAATGCAGCGG	LDLR	ENSG00000130164	-0.646566328845389	[3,3]	[2,0]	-8	hSpCas9	positive selection	3067014
11107385	11107408	19	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTCACAGTGACACTCTGCGAGG	LDLR	ENSG00000130164	-0.7706196162679867	[1,1]	[0,0]	-9	hSpCas9	positive selection	3067015
11107500	11107523		-	24336571	A375	resistance to PLX after 7 days	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.10487912049636439	[60,61]	[59,53]	-3	hSpCas9	positive selection	3124389
11110647	11110670		+	24336571	A375	resistance to PLX after 7 days	CGCAGGGACCAACGAATGCTTGG	LDLR	ENSG00000130164	-0.30750019241497517	[60,57]	[44,49]	-8	hSpCas9	positive selection	3124391
11107410	11107433		-	24336571	A375	resistance to PLX after 7 days	GCTGTGACACTTGAACTTGTTGG	LDLR	ENSG00000130164	0.1383017514338034	[57,53]	[60,60]	4	hSpCas9	positive selection	3124392
11110704	11110727		-	24336571	A375	resistance to PLX after 7 days	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.16043214391659033	[66,66]	[59,59]	-5	hSpCas9	positive selection	3124393
11107500	11107523		-	24336571	A375	resistance to PLX after 14 days	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.35830929423498104	[65,54]	[19,22]	-4	hSpCas9	positive selection	3182182
11110647	11110670		+	24336571	A375	resistance to PLX after 14 days	CGCAGGGACCAACGAATGCTTGG	LDLR	ENSG00000130164	-0.48148311384131515	[50,75]	[19,21]	-6	hSpCas9	positive selection	3182184
11107410	11107433		-	24336571	A375	resistance to PLX after 14 days	GCTGTGACACTTGAACTTGTTGG	LDLR	ENSG00000130164	2.753894621998459	[51,52]	[196,135]	9	hSpCas9	positive selection	3182185
11110704	11110727		-	24336571	A375	resistance to PLX after 14 days	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.8048852151129353	[70,69]	[17,18]	-8	hSpCas9	positive selection	3182186
11107500	11107523		-	24336571	A375	viability after 7 days	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.47989114919562814	[89]	[60,61]	-6	hSpCas9	negative selection	3239975
11110647	11110670		+	24336571	A375	viability after 7 days	CGCAGGGACCAACGAATGCTTGG	LDLR	ENSG00000130164	0.20597040472804573	[53]	[60,57]	3	hSpCas9	negative selection	3239977
11107410	11107433		-	24336571	A375	viability after 7 days	GCTGTGACACTTGAACTTGTTGG	LDLR	ENSG00000130164	-0.45281616438653005	[80]	[57,53]	-6	hSpCas9	negative selection	3239978
11110704	11110727		-	24336571	A375	viability after 7 days	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.24008209005742165	[59]	[66,66]	3	hSpCas9	negative selection	3239979
11107500	11107523		-	24336571	A375	viability after 14 days	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.48608141187719367	[89]	[65,54]	-5	hSpCas9	negative selection	3297768
11110647	11110670		+	24336571	A375	viability after 14 days	CGCAGGGACCAACGAATGCTTGG	LDLR	ENSG00000130164	0.31498284328210935	[53]	[50,75]	4	hSpCas9	negative selection	3297770
11107410	11107433		-	24336571	A375	viability after 14 days	GCTGTGACACTTGAACTTGTTGG	LDLR	ENSG00000130164	-0.5245243163965054	[80]	[51,52]	-6	hSpCas9	negative selection	3297771
11110704	11110727		-	24336571	A375	viability after 14 days	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.32167179983912453	[59]	[70,69]	4	hSpCas9	negative selection	3297772
11107500	11107523	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.9125987899964773	[287,287]	[0,0]	-6	hSpCas9	positive selection	3376952
11111602	11111625	19	+	27383988	293T	resistance to West Nile virus (flavivirus)	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	1.1698633701954957	[67,67]	[0,0]	5	hSpCas9	positive selection	3376953
11107447	11107470	19	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.9714924790500457	[599,599]	[1,1]	-6	hSpCas9	positive selection	3376954
11107446	11107469	19	-	26780180	HT29	viability (Avana library 4 designs)	CATGTTGCAGACTTTGTCCAGGG	LDLR	ENSG00000130164	0.655332239908934	[]	[]	2	hSpCas9	negative selection	3436695
11110660	11110683	19	+	26780180	HT29	viability (Avana library 4 designs)	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	2.12953799850962	[]	[]	7	hSpCas9	negative selection	3436696
11102713	11102736	19	-	26780180	HT29	viability (Avana library 4 designs)	TCCAGAACTGAGGAATGCAGCGG	LDLR	ENSG00000130164	0.763874102774151	[]	[]	3	hSpCas9	negative selection	3436697
11107384	11107407	19	+	26780180	HT29	viability (Avana library 4 designs)	TCTCACAGTGACACTCTGCGAGG	LDLR	ENSG00000130164	0.895878959649708	[]	[]	3	hSpCas9	negative selection	3436698
11102713	11102736	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCCAGAACTGAGGAATGCAGCGG	LDLR	ENSG00000130164	-5.92450305407156	[]	[]	-6	hSpCas9	negative selection	3525040
11110660	11110683	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-5.16413244920331	[]	[]	-5	hSpCas9	negative selection	3525041
11107446	11107469	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	CATGTTGCAGACTTTGTCCAGGG	LDLR	ENSG00000130164	2.52403599516563	[]	[]	4	hSpCas9	negative selection	3525042
11107384	11107407	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTCACAGTGACACTCTGCGAGG	LDLR	ENSG00000130164	-0.589855345090371	[]	[]	0	hSpCas9	negative selection	3525043
11113306	11113329	19	-	26780180	A375	viability (Avana lentiCRISPRv2)	TCATCTTCCTGACCTCGTGCCGG	LDLR	ENSG00000130164	-5.69002722451285	[]	[]	-6	hSpCas9	negative selection	3525044
11107493	11107516	19	+	26780180	A375	viability (Avana lentiCRISPRv2)	GATGAACCCATCAAAGAGTGCGG	LDLR	ENSG00000130164	0.577102763944805	[]	[]	0	hSpCas9	negative selection	3525045
11102713	11102736	19	-	26780180	A375	viability (Avana lentiGuide)	TCCAGAACTGAGGAATGCAGCGG	LDLR	ENSG00000130164	2.54406495601961	[]	[]	2	hSpCas9	negative selection	3633699
11110660	11110683	19	+	26780180	A375	viability (Avana lentiGuide)	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	1.25923778195773	[]	[]	1	hSpCas9	negative selection	3633700
11107446	11107469	19	-	26780180	A375	viability (Avana lentiGuide)	CATGTTGCAGACTTTGTCCAGGG	LDLR	ENSG00000130164	13.1118306618692	[]	[]	7	hSpCas9	negative selection	3633701
11107384	11107407	19	+	26780180	A375	viability (Avana lentiGuide)	TCTCACAGTGACACTCTGCGAGG	LDLR	ENSG00000130164	2.93302231505425	[]	[]	3	hSpCas9	negative selection	3633702
11113306	11113329	19	-	26780180	A375	viability (Avana lentiGuide)	TCATCTTCCTGACCTCGTGCCGG	LDLR	ENSG00000130164	6.7601289415971	[]	[]	5	hSpCas9	negative selection	3633703
11107493	11107516	19	+	26780180	A375	viability (Avana lentiGuide)	GATGAACCCATCAAAGAGTGCGG	LDLR	ENSG00000130164	3.51932688259075	[]	[]	3	hSpCas9	negative selection	3633704
11102713	11102736	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCCAGAACTGAGGAATGCAGCGG	LDLR	ENSG00000130164	-0.6676462792764459	[4]	[2,2]	-7	hSpCas9	positive selection	3742358
11110660	11110683	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.25073894810571495	[4]	[4,2]	-4	hSpCas9	positive selection	3742359
11107446	11107469	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATGTTGCAGACTTTGTCCAGGG	LDLR	ENSG00000130164	-0.25166793178373426	[4]	[3,4]	-4	hSpCas9	positive selection	3742360
11107384	11107407	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTCACAGTGACACTCTGCGAGG	LDLR	ENSG00000130164	-0.3203637042530485	[0]	[0,0]	-5	hSpCas9	positive selection	3742361
11113306	11113329	19	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCATCTTCCTGACCTCGTGCCGG	LDLR	ENSG00000130164	-1.3059398295455922	[4]	[0,1]	-9	hSpCas9	positive selection	3742362
11107493	11107516	19	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GATGAACCCATCAAAGAGTGCGG	LDLR	ENSG00000130164	-0.05172314208101694	[5]	[5,4]	-1	hSpCas9	positive selection	3742363
11102713	11102736	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCCAGAACTGAGGAATGCAGCGG	LDLR	ENSG00000130164	-0.14826055212933953	[4]	[2,4]	-2	hSpCas9	positive selection	3850965
11110660	11110683	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.8697679515351948	[5]	[0,0]	-9	hSpCas9	positive selection	3850966
11107446	11107469	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATGTTGCAGACTTTGTCCAGGG	LDLR	ENSG00000130164	-0.3448661987703184	[4]	[2,3]	-4	hSpCas9	positive selection	3850967
11107384	11107407	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTCACAGTGACACTCTGCGAGG	LDLR	ENSG00000130164	-0.4302210186991633	[0]	[0,0]	-5	hSpCas9	positive selection	3850968
11113306	11113329	19	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCATCTTCCTGACCTCGTGCCGG	LDLR	ENSG00000130164	-0.4317992880783029	[5]	[4,2]	-5	hSpCas9	positive selection	3850969
11107493	11107516	19	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GATGAACCCATCAAAGAGTGCGG	LDLR	ENSG00000130164	-0.038173695351317496	[5]	[4,4]	0	hSpCas9	positive selection	3850970
11107500	11107523	19	-	26780180	A375	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	1.34069594562829	[]	[]	7	hSpCas9	negative selection	3956655
11111602	11111625	19	+	26780180	A375	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	1.22329411741466	[]	[]	6	hSpCas9	negative selection	3956656
11107447	11107470	19	-	26780180	A375	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	1.55424391742512	[]	[]	8	hSpCas9	negative selection	3956657
11110704	11110727	19	-	26780180	A375	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.0614642321629882	[]	[]	0	hSpCas9	negative selection	3956658
11110750	11110773	19	+	26780180	A375	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.856499387560909	[]	[]	3	hSpCas9	negative selection	3956659
11111509	11111532	19	+	26780180	A375	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.829103215013581	[]	[]	3	hSpCas9	negative selection	3956660
11107500	11107523	19	-	26780180	HT29	viability (GeCKOv2 library)	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	1.39529050482623	[]	[]	7	hSpCas9	negative selection	4064621
11111602	11111625	19	+	26780180	HT29	viability (GeCKOv2 library)	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	1.53975923968779	[]	[]	7	hSpCas9	negative selection	4064622
11107447	11107470	19	-	26780180	HT29	viability (GeCKOv2 library)	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	1.75021485873743	[]	[]	8	hSpCas9	negative selection	4064623
11110704	11110727	19	-	26780180	HT29	viability (GeCKOv2 library)	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.73248146192138	[]	[]	3	hSpCas9	negative selection	4064624
11110750	11110773	19	+	26780180	HT29	viability (GeCKOv2 library)	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	1.07173583380755	[]	[]	5	hSpCas9	negative selection	4064625
11111509	11111532	19	+	26780180	HT29	viability (GeCKOv2 library)	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	1.12817285133624	[]	[]	5	hSpCas9	negative selection	4064626
11107500	11107523	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.30435439798352215	[5]	[5,4]	7	hSpCas9	positive selection	4148413
11110647	11110670	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGCAGGGACCAACGAATGCTTGG	LDLR	ENSG00000130164	0.005472755328029932	[5]	[3,4]	0	hSpCas9	positive selection	4148415
11107410	11107433	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GCTGTGACACTTGAACTTGTTGG	LDLR	ENSG00000130164	0.49771302565493347	[5]	[4,7]	9	hSpCas9	positive selection	4148416
11110704	11110727	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.14704684534639878	[5]	[4,4]	4	hSpCas9	positive selection	4148417
11107500	11107523	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.10359276485828905	[6]	[4,4,2,0]	-1	hSpCas9	positive selection	4212435
11110647	11110670	19	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGCAGGGACCAACGAATGCTTGG	LDLR	ENSG00000130164	0.6036331356681393	[5]	[3,4,1,3]	4	hSpCas9	positive selection	4212437
11107410	11107433	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GCTGTGACACTTGAACTTGTTGG	LDLR	ENSG00000130164	1.0393445163059152	[6]	[6,5,4,6]	7	hSpCas9	positive selection	4212438
11110704	11110727	19	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	1.1334085390477722	[5]	[4,5,6,4]	8	hSpCas9	positive selection	4212439
11110704	11110727	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.20042797984607552	[0]	[0,0]	-4	hSpCas9	positive selection	4279908
11110750	11110773	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.10206100371585763	[3]	[2,2]	2	hSpCas9	positive selection	4279909
11111509	11111532	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.14735520407615016	[4]	[3,3]	3	hSpCas9	positive selection	4279910
11107500	11107523	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.39072581993743505	[3]	[2,1]	-7	hSpCas9	positive selection	4344164
11111602	11111625	19	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.35208360004338013	[2]	[1,0]	-6	hSpCas9	positive selection	4344165
11107447	11107470	19	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	0.1549288515134355	[4]	[4,4]	3	hSpCas9	positive selection	4344166
11100277	11100299	19	+	27760321	OCIAML3	viability	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.6878402412040597	[937,798]	[319,550]	-6	hSpCas9	negative selection	4414092
11107386	11107408	19	+	27760321	OCIAML3	viability	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.48476249401794985	[615,531]	[302,341]	-5	hSpCas9	negative selection	4414093
11107430	11107452	19	+	27760321	OCIAML3	viability	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	-1.3288946612379158	[816,556]	[156,281]	-8	hSpCas9	negative selection	4414094
11110751	11110773	19	+	27760321	OCIAML3	viability	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.20045201160937776	[393,281]	[162,311]	-2	hSpCas9	negative selection	4414095
11113367	11113389	19	+	27760321	OCIAML3	viability	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-1.0789575083429694	[591,549]	[220,198]	-7	hSpCas9	negative selection	4414096
11100277	11100299	19	+	27760321	OCIAML2	viability	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.7257108692561776	[937,798]	[356,510]	-6	hSpCas9	negative selection	4497555
11107386	11107408	19	+	27760321	OCIAML2	viability	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.48821683976239577	[615,531]	[289,382]	-5	hSpCas9	negative selection	4497556
11107430	11107452	19	+	27760321	OCIAML2	viability	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	-0.9991162027235321	[816,556]	[284,260]	-7	hSpCas9	negative selection	4497557
11110751	11110773	19	+	27760321	OCIAML2	viability	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.11332292506439628	[393,281]	[249,348]	1	hSpCas9	negative selection	4497558
11113367	11113389	19	+	27760321	OCIAML2	viability	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.47305366877485044	[591,549]	[309,362]	-5	hSpCas9	negative selection	4497559
11100277	11100299	19	+	27760321	MV411	viability	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-1.0977984819534874	[937,798]	[146,446]	-6	hSpCas9	negative selection	4581018
11107386	11107408	19	+	27760321	MV411	viability	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-1.2428107631173704	[615,531]	[181,125]	-7	hSpCas9	negative selection	4581019
11107430	11107452	19	+	27760321	MV411	viability	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	-1.017592232649673	[816,556]	[203,246]	-6	hSpCas9	negative selection	4581020
11110751	11110773	19	+	27760321	MV411	viability	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.3648286765603973	[393,281]	[115,536]	2	hSpCas9	negative selection	4581021
11113367	11113389	19	+	27760321	MV411	viability	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-1.2184961133996492	[591,549]	[121,221]	-7	hSpCas9	negative selection	4581022
11100277	11100299	19	+	27760321	HL60	viability	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.1418157999387144	[937,798]	[538,748]	-2	hSpCas9	negative selection	4664481
11107386	11107408	19	+	27760321	HL60	viability	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.43806586681291176	[615,531]	[399,286]	-5	hSpCas9	negative selection	4664482
11107430	11107452	19	+	27760321	HL60	viability	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	-0.005997814924719402	[816,556]	[618,480]	0	hSpCas9	negative selection	4664483
11110751	11110773	19	+	27760321	HL60	viability	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.806288851708677	[393,281]	[422,535]	8	hSpCas9	negative selection	4664484
11113367	11113389	19	+	27760321	HL60	viability	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.8160951034007595	[591,549]	[297,229]	-7	hSpCas9	negative selection	4664485
11100277	11100299	19	+	27760321	HT1080	viability	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.5830710425859743	[798,623]	[256,114]	-3	hSpCas9	negative selection	4747944
11107386	11107408	19	+	27760321	HT1080	viability	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.6097103136345339	[531,414]	[146,97]	-3	hSpCas9	negative selection	4747945
11107430	11107452	19	+	27760321	HT1080	viability	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	-0.8329272752681502	[556,434]	[119,100]	-3	hSpCas9	negative selection	4747946
11110751	11110773	19	+	27760321	HT1080	viability	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.6613313239957044	[281,219]	[160,154]	3	hSpCas9	negative selection	4747947
11113367	11113389	19	+	27760321	HT1080	viability	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	0.33913760038119656	[549,428]	[49,461]	1	hSpCas9	negative selection	4747948
11100277	11100299	19	+	27760321	HT29	viability after 7 days	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	0.15735935248050015	[798,623]	[1076,767,1215]	2	hSpCas9	negative selection	4831407
11107386	11107408	19	+	27760321	HT29	viability after 7 days	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.16755394947647423	[531,414]	[492,669,457]	-2	hSpCas9	negative selection	4831408
11107430	11107452	19	+	27760321	HT29	viability after 7 days	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	0.1937870539788869	[556,434]	[916,727,573]	3	hSpCas9	negative selection	4831409
11110751	11110773	19	+	27760321	HT29	viability after 7 days	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.18587699199587338	[281,219]	[500,257,360]	3	hSpCas9	negative selection	4831410
11113367	11113389	19	+	27760321	HT29	viability after 7 days	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.07318428744567346	[549,428]	[679,545,579]	-1	hSpCas9	negative selection	4831411
11100277	11100299	19	+	27760321	HT29	viability after 25 days	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.12834775510854657	[798,623]	[794,726,700]	-1	hSpCas9	negative selection	4914870
11107386	11107408	19	+	27760321	HT29	viability after 25 days	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.5720477328484969	[531,414]	[244,376,489]	-5	hSpCas9	negative selection	4914871
11107430	11107452	19	+	27760321	HT29	viability after 25 days	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	0.04628152710871908	[556,434]	[416,743,606]	0	hSpCas9	negative selection	4914872
11110751	11110773	19	+	27760321	HT29	viability after 25 days	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.46581148582014403	[281,219]	[434,219,545]	5	hSpCas9	negative selection	4914873
11113367	11113389	19	+	27760321	HT29	viability after 25 days	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.25680057549138546	[549,428]	[525,510,350]	-3	hSpCas9	negative selection	4914874
11100277	11100299	19	+	27760321	HT29	viability after 22 days	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	0.11437725799083487	[798,623]	[753,919,1001]	1	hSpCas9	negative selection	4998333
11107386	11107408	19	+	27760321	HT29	viability after 22 days	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.34389750411371717	[531,414]	[303,484,508]	-3	hSpCas9	negative selection	4998334
11107430	11107452	19	+	27760321	HT29	viability after 22 days	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	0.24515981658070668	[556,434]	[588,597,855]	2	hSpCas9	negative selection	4998335
11110751	11110773	19	+	27760321	HT29	viability after 22 days	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.2069977962222488	[281,219]	[326,236,441]	2	hSpCas9	negative selection	4998336
11113367	11113389	19	+	27760321	HT29	viability after 22 days	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.2667392303049146	[549,428]	[628,487,287]	-3	hSpCas9	negative selection	4998337
11100277	11100299	19	+	27760321	HT29	viability after 19 days	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	0.0749636087661103	[798,623]	[1217,863,538]	0	hSpCas9	negative selection	5081796
11107386	11107408	19	+	27760321	HT29	viability after 19 days	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.041653394124884724	[531,414]	[400,391,850]	0	hSpCas9	negative selection	5081797
11107430	11107452	19	+	27760321	HT29	viability after 19 days	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	0.14907630890071372	[556,434]	[604,832,452]	1	hSpCas9	negative selection	5081798
11110751	11110773	19	+	27760321	HT29	viability after 19 days	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.6373125631437392	[281,219]	[334,183,794]	6	hSpCas9	negative selection	5081799
11113367	11113389	19	+	27760321	HT29	viability after 19 days	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.28189347298170897	[549,428]	[623,389,386]	-3	hSpCas9	negative selection	5081800
11100277	11100299	19	+	27760321	HT29	viability after 16 days	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.06759814966623812	[798,623]	[1015,719,567]	0	hSpCas9	negative selection	5165259
11107386	11107408	19	+	27760321	HT29	viability after 16 days	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.41272438032928366	[531,414]	[358,400,429]	-4	hSpCas9	negative selection	5165260
11107430	11107452	19	+	27760321	HT29	viability after 16 days	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	0.5905864716933513	[556,434]	[993,714,815]	6	hSpCas9	negative selection	5165261
11110751	11110773	19	+	27760321	HT29	viability after 16 days	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.3372885166976296	[281,219]	[356,257,451]	4	hSpCas9	negative selection	5165262
11113367	11113389	19	+	27760321	HT29	viability after 16 days	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.717818900072565	[549,428]	[345,412,238]	-6	hSpCas9	negative selection	5165263
11100277	11100299	19	+	27760321	HT29	viability after 13 days	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	0.12735176566468343	[798,623]	[1315,643,752]	1	hSpCas9	negative selection	5248722
11107386	11107408	19	+	27760321	HT29	viability after 13 days	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.36688569515718633	[531,414]	[276,555,443]	-4	hSpCas9	negative selection	5248723
11107430	11107452	19	+	27760321	HT29	viability after 13 days	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	0.4343228586295476	[556,434]	[843,788,703]	5	hSpCas9	negative selection	5248724
11110751	11110773	19	+	27760321	HT29	viability after 13 days	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.2667664593215649	[281,219]	[446,241,360]	3	hSpCas9	negative selection	5248725
11113367	11113389	19	+	27760321	HT29	viability after 13 days	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	-0.5386211243059217	[549,428]	[395,356,417]	-6	hSpCas9	negative selection	5248726
11100277	11100299	19	+	27760321	HT29	viability after 10 days	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.27650558174646056	[798,623]	[821,729,649]	-4	hSpCas9	negative selection	5332185
11107386	11107408	19	+	27760321	HT29	viability after 10 days	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.16388960453539952	[531,414]	[527,567,488]	-2	hSpCas9	negative selection	5332186
11107430	11107452	19	+	27760321	HT29	viability after 10 days	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	0.19157446651226023	[556,434]	[743,777,603]	2	hSpCas9	negative selection	5332187
11110751	11110773	19	+	27760321	HT29	viability after 10 days	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.6706429916751375	[281,219]	[547,207,726]	8	hSpCas9	negative selection	5332188
11113367	11113389	19	+	27760321	HT29	viability after 10 days	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	0.0038600427793697434	[549,428]	[509,733,597]	0	hSpCas9	negative selection	5332189
11100277	11100299	19	+	27760321	MOLM13	viability	CCTACAAGTGGGTCTGCGATGG	LDLR	ENSG00000130164	-0.3397580660149556	[937,798]	[265,487]	-2	hSpCas9	negative selection	5415648
11107386	11107408	19	+	27760321	MOLM13	viability	TCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.24436102189783346	[615,531]	[189,342]	-2	hSpCas9	negative selection	5415649
11107430	11107452	19	+	27760321	MOLM13	viability	AGCGGCGAATGCATCACCCTGG	LDLR	ENSG00000130164	-0.6819423623303217	[816,556]	[229,245]	-4	hSpCas9	negative selection	5415650
11110751	11110773	19	+	27760321	MOLM13	viability	TGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-1.5606816587614896	[393,281]	[70,57]	-7	hSpCas9	negative selection	5415651
11113367	11113389	19	+	27760321	MOLM13	viability	CTGAGGAACGTGGTCGCTCTGG	LDLR	ENSG00000130164	0.11337003802237877	[591,549]	[64,589]	0	hSpCas9	negative selection	5415652
11089496	11089519	19	+	27661255	K562	viability	GACACAGCAGGTCGTGATCCGGG	LDLR	ENSG00000130164	-0.22819198884382486	[1090,1065]	[846,640]	-6	dCas9-KRAB	negative selection	5490009
11089540	11089563	19	+	27661255	K562	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	-0.08160348497120662	[1142,1069]	[913,769]	-3	dCas9-KRAB	negative selection	5490010
11110704	11110727	19	-	27260156	BXPC3	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.17710563112869915	[64]	[68,87,88,58]	4	hSpCas9	negative selection	5552368
11110750	11110773	19	+	27260156	BXPC3	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.6215688356213356	[514]	[262,382,278,496]	-8	hSpCas9	negative selection	5552369
11111509	11111532	19	+	27260156	BXPC3	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.007625967197335992	[1118]	[900,1120,1221,1473]	0	hSpCas9	negative selection	5552370
11107500	11107523	19	-	27260156	BXPC3	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.404394917840628	[695]	[578,538,444,638]	-7	hSpCas9	negative selection	5616624
11111602	11111625	19	+	27260156	BXPC3	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.12252941643182569	[334]	[396,275,237,372]	-3	hSpCas9	negative selection	5616625
11107447	11107470	19	-	27260156	BXPC3	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.615562525731632	[1969]	[1280,1316,1361,1426]	-8	hSpCas9	negative selection	5616626
11110704	11110727	19	-	27260156	A673	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.45729383378615784	[64]	[130,106,105,85]	8	hSpCas9	negative selection	5673619
11110750	11110773	19	+	27260156	A673	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.36675332702266145	[514]	[532,480,340,574]	-7	hSpCas9	negative selection	5673620
11111509	11111532	19	+	27260156	A673	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.028606119357246662	[1118]	[1438,1182,1265,1400]	0	hSpCas9	negative selection	5673621
11107500	11107523	19	-	27260156	A673	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.16824934458239033	[695]	[717,608,762,891]	-4	hSpCas9	negative selection	5737875
11111602	11111625	19	+	27260156	A673	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.3906586738023491	[334]	[327,291,266,344]	-7	hSpCas9	negative selection	5737876
11107447	11107470	19	-	27260156	A673	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.2789423934476478	[1969]	[2256,1761,1699,2127]	-6	hSpCas9	negative selection	5737877
11110704	11110727	19	-	27260156	A375	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.21105363187008042	[64]	[120,184,17,45]	3	hSpCas9	negative selection	5794870
11110750	11110773	19	+	27260156	A375	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.21307446988492235	[514]	[609,638,405,444]	-3	hSpCas9	negative selection	5794871
11111509	11111532	19	+	27260156	A375	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.09742211687306934	[1118]	[1409,1548,1678,1016]	1	hSpCas9	negative selection	5794872
11107500	11107523	19	-	27260156	A375	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.3066252213133305	[695]	[636,872,688,478]	-4	hSpCas9	negative selection	5859126
11111602	11111625	19	+	27260156	A375	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.7271895326261332	[334]	[215,275,277,185]	-7	hSpCas9	negative selection	5859127
11107447	11107470	19	-	27260156	A375	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.3938210129704871	[1969]	[1528,1863,1966,1662]	-5	hSpCas9	negative selection	5859128
11110704	11110727	19	-	27260156	COLO741	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.4508626142247705	[64]	[75,40,65]	-7	hSpCas9	negative selection	5916121
11110750	11110773	19	+	27260156	COLO741	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.1835481875148865	[514]	[641,379,709]	-4	hSpCas9	negative selection	5916122
11111509	11111532	19	+	27260156	COLO741	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.09581630042504052	[1118]	[1650,1598,1353]	2	hSpCas9	negative selection	5916123
11107500	11107523	19	-	27260156	COLO741	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.06851217912132013	[695]	[1114,907,797]	1	hSpCas9	negative selection	5980377
11111602	11111625	19	+	27260156	COLO741	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.3387658784001576	[334]	[291,327,386]	-6	hSpCas9	negative selection	5980378
11107447	11107470	19	-	27260156	COLO741	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.18044378759776514	[1969]	[2369,2430,1894]	-4	hSpCas9	negative selection	5980379
11110704	11110727	19	-	27260156	CAL120	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.2689635394732086	[64]	[86,174,29]	4	hSpCas9	negative selection	6037372
11110750	11110773	19	+	27260156	CAL120	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.17979182102354235	[514]	[700,482,533]	-3	hSpCas9	negative selection	6037373
11111509	11111532	19	+	27260156	CAL120	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.5934114766935408	[1118]	[2326,2631,1389]	8	hSpCas9	negative selection	6037374
11107500	11107523	19	-	27260156	CAL120	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.058173754395872135	[695]	[949,673,887]	-1	hSpCas9	negative selection	6101628
11111602	11111625	19	+	27260156	CAL120	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.5221372702375352	[334]	[199,246,407]	-6	hSpCas9	negative selection	6101629
11107447	11107470	19	-	27260156	CAL120	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.2693765649693516	[1969]	[2626,1466,2094]	-4	hSpCas9	negative selection	6101630
11110704	11110727	19	-	27260156	CADOES1	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.19199286266877902	[64]	[63,35,48,62]	-3	hSpCas9	negative selection	6158623
11110750	11110773	19	+	27260156	CADOES1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.1197215734267596	[514]	[375,574,366,445]	-2	hSpCas9	negative selection	6158624
11111509	11111532	19	+	27260156	CADOES1	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.16956029140504958	[1118]	[1190,1045,1166,1281]	3	hSpCas9	negative selection	6158625
11107500	11107523	19	-	27260156	CADOES1	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.25236482483562916	[695]	[517,549,506,600]	-4	hSpCas9	negative selection	6222879
11111602	11111625	19	+	27260156	CADOES1	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.33553666536349624	[334]	[327,196,300,157]	-5	hSpCas9	negative selection	6222880
11107447	11107470	19	-	27260156	CADOES1	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.13471148729281346	[1969]	[1562,1634,1723,1756]	-2	hSpCas9	negative selection	6222881
11110704	11110727	19	-	27260156	EWS502	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.15885408136562074	[64]	[105,44,32,56]	-3	hSpCas9	negative selection	6279874
11110750	11110773	19	+	27260156	EWS502	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.3192438419214312	[514]	[373,470,420,490]	-5	hSpCas9	negative selection	6279875
11111509	11111532	19	+	27260156	EWS502	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.10303202252140076	[1118]	[1314,1192,1215,1366]	1	hSpCas9	negative selection	6279876
11107500	11107523	19	-	27260156	EWS502	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.036966099678062414	[695]	[636,684,893,830]	0	hSpCas9	negative selection	6344130
11111602	11111625	19	+	27260156	EWS502	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.3865398287334897	[334]	[229,252,229,384]	-6	hSpCas9	negative selection	6344131
11107447	11107470	19	-	27260156	EWS502	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.3182927153850068	[1969]	[1508,1603,1986,1609]	-5	hSpCas9	negative selection	6344132
11110704	11110727	19	-	27260156	EW8	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.7223351770188748	[64]	[59,108,137,28]	9	hSpCas9	negative selection	6401125
11110750	11110773	19	+	27260156	EW8	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.07086875630182579	[514]	[476,353,473,444]	1	hSpCas9	negative selection	6401126
11111509	11111532	19	+	27260156	EW8	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.04583383217193626	[1118]	[1142,744,687,995]	-1	hSpCas9	negative selection	6401127
11107500	11107523	19	-	27260156	EW8	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.2265080252713252	[695]	[684,598,480,904]	4	hSpCas9	negative selection	6465381
11111602	11111625	19	+	27260156	EW8	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.2870994521702551	[334]	[281,246,175,198]	-5	hSpCas9	negative selection	6465382
11107447	11107470	19	-	27260156	EW8	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.26110041208140844	[1969]	[1306,1440,1241,1347]	-5	hSpCas9	negative selection	6465383
11110704	11110727	19	-	27260156	CORL105	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.5434839939440352	[64]	[43,66,37,56]	-7	hSpCas9	negative selection	6522376
11110750	11110773	19	+	27260156	CORL105	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.6008673700138192	[514]	[390,383,372,437]	-8	hSpCas9	negative selection	6522377
11111509	11111532	19	+	27260156	CORL105	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.10359222685653835	[1118]	[1395,1362,1739,1183]	2	hSpCas9	negative selection	6522378
11107500	11107523	19	-	27260156	CORL105	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.2724683106167542	[695]	[667,708,722,604]	-5	hSpCas9	negative selection	6586632
11111602	11111625	19	+	27260156	CORL105	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.44682114514169236	[334]	[322,227,280,319]	-7	hSpCas9	negative selection	6586633
11107447	11107470	19	-	27260156	CORL105	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.37754454318842723	[1969]	[1429,1946,2191,1581]	-6	hSpCas9	negative selection	6586634
11110704	11110727	19	-	27260156	HS294T	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.4332455965820543	[64]	[12,72,12,37]	6	hSpCas9	negative selection	6643627
11110750	11110773	19	+	27260156	HS294T	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.2617291071169675	[514]	[110,184,113,276]	-4	hSpCas9	negative selection	6643628
11111509	11111532	19	+	27260156	HS294T	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.091009501755555	[1118]	[398,366,370,504]	-1	hSpCas9	negative selection	6643629
11107500	11107523	19	-	27260156	HS294T	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.4603691034928902	[695]	[174,130,223,267]	-6	hSpCas9	negative selection	6707883
11111602	11111625	19	+	27260156	HS294T	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.9346662944398224	[334]	[38,38,86,117]	-8	hSpCas9	negative selection	6707884
11107447	11107470	19	-	27260156	HS294T	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	0.06709541436046251	[1969]	[989,597,797,789]	0	hSpCas9	negative selection	6707885
11110704	11110727	19	-	27260156	HCC44	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.23984727416815899	[64]	[56,97,87,98]	4	hSpCas9	negative selection	6764878
11110750	11110773	19	+	27260156	HCC44	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.3268745865435797	[514]	[784,611,1128,488]	5	hSpCas9	negative selection	6764879
11111509	11111532	19	+	27260156	HCC44	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.36584103331298645	[1118]	[1809,1216,2634,1113]	6	hSpCas9	negative selection	6764880
11107500	11107523	19	-	27260156	HCC44	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.3571143367306243	[695]	[1190,759,1367,825]	6	hSpCas9	negative selection	6829134
11111602	11111625	19	+	27260156	HCC44	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	0.19767343413697452	[334]	[380,716,377,210]	3	hSpCas9	negative selection	6829135
11107447	11107470	19	-	27260156	HCC44	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.2131362904928924	[1969]	[2236,1661,2175,1713]	-3	hSpCas9	negative selection	6829136
11110704	11110727	19	-	27260156	G402	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.6061766112381237	[64]	[46,34,40,81]	-6	hSpCas9	negative selection	6886129
11110750	11110773	19	+	27260156	G402	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.7644121854860222	[514]	[370,359,336,407]	-7	hSpCas9	negative selection	6886130
11111509	11111532	19	+	27260156	G402	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.4972904514739225	[1118]	[1893,2118,2207,1507]	6	hSpCas9	negative selection	6886131
11107500	11107523	19	-	27260156	G402	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.5858818090913424	[695]	[684,720,584,308]	-6	hSpCas9	negative selection	6950385
11111602	11111625	19	+	27260156	G402	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.8333543465773822	[334]	[304,162,166,285]	-7	hSpCas9	negative selection	6950386
11107447	11107470	19	-	27260156	G402	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.12366958084201185	[1969]	[3239,1616,2212,1877]	-1	hSpCas9	negative selection	6950387
11110704	11110727	19	-	27260156	L33	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.7226932795584586	[64]	[63,8,28,24]	-9	hSpCas9	negative selection	7007380
11110750	11110773	19	+	27260156	L33	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.031090299774096164	[514]	[425,245,367,495]	0	hSpCas9	negative selection	7007381
11111509	11111532	19	+	27260156	L33	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.0464779066609875	[1118]	[990,448,717,1394]	1	hSpCas9	negative selection	7007382
11107500	11107523	19	-	27260156	L33	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.018367611179532672	[695]	[578,307,492,707]	0	hSpCas9	negative selection	7071636
11111602	11111625	19	+	27260156	L33	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.024204382352012832	[334]	[361,125,215,303]	0	hSpCas9	negative selection	7071637
11107447	11107470	19	-	27260156	L33	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.2969345446161369	[1969]	[1462,653,995,1771]	-6	hSpCas9	negative selection	7071638
11110704	11110727	19	-	27260156	K562	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	1.403387994963737	[64]	[503,96,8,38]	9	hSpCas9	negative selection	7128631
11110750	11110773	19	+	27260156	K562	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.7455639851682021	[514]	[337,360,257,155]	-7	hSpCas9	negative selection	7128632
11111509	11111532	19	+	27260156	K562	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.39030708422966365	[1118]	[1333,1650,1202,1061]	5	hSpCas9	negative selection	7128633
11107500	11107523	19	-	27260156	K562	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.060443964795375504	[695]	[764,596,227,769]	0	hSpCas9	negative selection	7192887
11111602	11111625	19	+	27260156	K562	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.5783821536049224	[334]	[216,284,170,135]	-6	hSpCas9	negative selection	7192888
11107447	11107470	19	-	27260156	K562	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.2848894643402393	[1969]	[1594,1172,1293,1645]	-4	hSpCas9	negative selection	7192889
11110704	11110727	19	-	27260156	HT29	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.17868132030946438	[64]	[118,120,67,57]	3	hSpCas9	negative selection	7249882
11110750	11110773	19	+	27260156	HT29	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.12208386071650337	[514]	[566,578,606,546]	-3	hSpCas9	negative selection	7249883
11111509	11111532	19	+	27260156	HT29	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.07475639483136409	[1118]	[1383,1740,1420,1222]	1	hSpCas9	negative selection	7249884
11107500	11107523	19	-	27260156	HT29	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.23937005102625242	[695]	[911,640,679,645]	-5	hSpCas9	negative selection	7314138
11111602	11111625	19	+	27260156	HT29	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	0.10892395159533652	[334]	[368,481,436,460]	2	hSpCas9	negative selection	7314139
11107447	11107470	19	-	27260156	HT29	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.08080999613815654	[1969]	[2352,2079,2139,2436]	-2	hSpCas9	negative selection	7314140
11110704	11110727	19	-	27260156	MHHES1	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.02287878619132666	[64]	[109,25,80,69]	0	hSpCas9	negative selection	7371133
11110750	11110773	19	+	27260156	MHHES1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.3595769975822545	[514]	[529,332,741,241]	-6	hSpCas9	negative selection	7371134
11111509	11111532	19	+	27260156	MHHES1	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.17551212137442418	[1118]	[1276,1239,1189,830]	-3	hSpCas9	negative selection	7371135
11107500	11107523	19	-	27260156	MHHES1	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.21200317911414873	[695]	[906,790,664,426]	-4	hSpCas9	negative selection	7435389
11111602	11111625	19	+	27260156	MHHES1	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.7118298502265327	[334]	[363,188,237,154]	-8	hSpCas9	negative selection	7435390
11107447	11107470	19	-	27260156	MHHES1	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.13973845707035926	[1969]	[2130,2808,2025,1305]	-3	hSpCas9	negative selection	7435391
11110704	11110727	19	-	27260156	MEWO	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.18106218690708298	[64]	[100,73,37]	4	hSpCas9	negative selection	7492384
11110750	11110773	19	+	27260156	MEWO	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.15203941331533483	[514]	[515,374,711]	3	hSpCas9	negative selection	7492385
11111509	11111532	19	+	27260156	MEWO	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.028667322314743338	[1118]	[1254,1010,973]	0	hSpCas9	negative selection	7492386
11107500	11107523	19	-	27260156	MEWO	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.12217087123831627	[695]	[660,643,811]	2	hSpCas9	negative selection	7556640
11111602	11111625	19	+	27260156	MEWO	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.3036670200049941	[334]	[263,185,313]	-6	hSpCas9	negative selection	7556641
11107447	11107470	19	-	27260156	MEWO	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.3036774983157331	[1969]	[1497,1542,1438]	-6	hSpCas9	negative selection	7556642
11110704	11110727	19	-	27260156	LNCAPCLONEFGC	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.7749384868331015	[64]	[168,63,86,81]	9	hSpCas9	negative selection	7613635
11110750	11110773	19	+	27260156	LNCAPCLONEFGC	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.47623897941199667	[514]	[221,324,381,421]	-6	hSpCas9	negative selection	7613636
11111509	11111532	19	+	27260156	LNCAPCLONEFGC	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.2119518389688686	[1118]	[845,775,1136,786]	-3	hSpCas9	negative selection	7613637
11107500	11107523	19	-	27260156	LNCAPCLONEFGC	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.1602899013492427	[695]	[493,479,676,628]	-3	hSpCas9	negative selection	7677891
11111602	11111625	19	+	27260156	LNCAPCLONEFGC	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.6209635843940408	[334]	[179,219,129,247]	-7	hSpCas9	negative selection	7677892
11107447	11107470	19	-	27260156	LNCAPCLONEFGC	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.5732044983821296	[1969]	[1123,992,1778,1001]	-7	hSpCas9	negative selection	7677893
11110704	11110727	19	-	27260156	PANC0327	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.10563479804998455	[64]	[116,28,38,37]	-1	hSpCas9	negative selection	7734886
11110750	11110773	19	+	27260156	PANC0327	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.6425362314814802	[514]	[289,367,183,319]	-7	hSpCas9	negative selection	7734887
11111509	11111532	19	+	27260156	PANC0327	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.1203240867784845	[1118]	[1274,846,883,689]	-2	hSpCas9	negative selection	7734888
11107500	11107523	19	-	27260156	PANC0327	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.10531919515252164	[695]	[572,468,792,842]	1	hSpCas9	negative selection	7799142
11111602	11111625	19	+	27260156	PANC0327	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.2371116385847526	[334]	[235,162,262,357]	-4	hSpCas9	negative selection	7799143
11107447	11107470	19	-	27260156	PANC0327	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.3414221335488594	[1969]	[2082,831,1474,1262]	-5	hSpCas9	negative selection	7799144
11110704	11110727	19	-	27260156	NCIH2009	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.1165267383894788	[64]	[92,104,95]	1	hSpCas9	negative selection	7856137
11110750	11110773	19	+	27260156	NCIH2009	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.3990198623008108	[514]	[737,441,495]	-5	hSpCas9	negative selection	7856138
11111509	11111532	19	+	27260156	NCIH2009	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.20405773420111917	[1118]	[1649,1092,1388]	-3	hSpCas9	negative selection	7856139
11107500	11107523	19	-	27260156	NCIH2009	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.022741287725345005	[695]	[1032,1034,901]	0	hSpCas9	negative selection	7920393
11111602	11111625	19	+	27260156	NCIH2009	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.8888541990004956	[334]	[245,281,227]	-8	hSpCas9	negative selection	7920394
11107447	11107470	19	-	27260156	NCIH2009	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.424340227377876	[1969]	[2167,1925,2080]	-5	hSpCas9	negative selection	7920395
11110704	11110727	19	-	27260156	NCIH1373	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.4121610732755463	[64]	[34,232,39,13]	4	hSpCas9	negative selection	7977388
11110750	11110773	19	+	27260156	NCIH1373	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.7036885998508566	[514]	[511,252,367,82]	-6	hSpCas9	negative selection	7977389
11111509	11111532	19	+	27260156	NCIH1373	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.2801378770609695	[1118]	[1781,1282,1488,420]	2	hSpCas9	negative selection	7977390
11107500	11107523	19	-	27260156	NCIH1373	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.05440458741705356	[695]	[1050,698,817,186]	0	hSpCas9	negative selection	8041644
11111602	11111625	19	+	27260156	NCIH1373	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.18184589694036557	[334]	[235,182,263,173]	-2	hSpCas9	negative selection	8041645
11107447	11107470	19	-	27260156	NCIH1373	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.04093050217704075	[1969]	[3224,1856,1893,467]	0	hSpCas9	negative selection	8041646
11110704	11110727	19	-	27260156	PATU8902	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.598089430720286	[64]	[148,45,18,393]	6	hSpCas9	negative selection	8098639
11110750	11110773	19	+	27260156	PATU8902	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.15952840068458302	[514]	[762,1190,520,796]	1	hSpCas9	negative selection	8098640
11111509	11111532	19	+	27260156	PATU8902	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.914337876687412	[1118]	[2353,3736,2317,3561]	8	hSpCas9	negative selection	8098641
11107500	11107523	19	-	27260156	PATU8902	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.26933156793028357	[695]	[1529,1055,1178,852]	2	hSpCas9	negative selection	8162895
11111602	11111625	19	+	27260156	PATU8902	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.4434652450815886	[334]	[348,343,215,513]	-4	hSpCas9	negative selection	8162896
11107447	11107470	19	-	27260156	PATU8902	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.41073297999604286	[1969]	[1741,2411,1576,2717]	-4	hSpCas9	negative selection	8162897
11110704	11110727	19	-	27260156	PANC1	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.11491970054822565	[64]	[32,70,80,58]	1	hSpCas9	negative selection	8219890
11110750	11110773	19	+	27260156	PANC1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.826980244795591	[514]	[365,230,225,175]	-8	hSpCas9	negative selection	8219891
11111509	11111532	19	+	27260156	PANC1	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.031675713866827326	[1118]	[997,1508,677,854]	0	hSpCas9	negative selection	8219892
11107500	11107523	19	-	27260156	PANC1	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.5110579415322819	[695]	[329,602,449,340]	-6	hSpCas9	negative selection	8284146
11111602	11111625	19	+	27260156	PANC1	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.68503700141398	[334]	[249,292,114,90]	-7	hSpCas9	negative selection	8284147
11107447	11107470	19	-	27260156	PANC1	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.4356163222291438	[1969]	[1265,1625,1197,1009]	-6	hSpCas9	negative selection	8284148
11110704	11110727	19	-	27260156	PANC0813	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.3558102538892527	[64]	[66,67,58,45]	-5	hSpCas9	negative selection	8341141
11110750	11110773	19	+	27260156	PANC0813	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.4054291551367685	[514]	[485,512,364,463]	-6	hSpCas9	negative selection	8341142
11111509	11111532	19	+	27260156	PANC0813	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.03302296058131282	[1118]	[1344,1429,1518,1097]	0	hSpCas9	negative selection	8341143
11107500	11107523	19	-	27260156	PANC0813	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.2099107638916528	[695]	[725,785,617,697]	-3	hSpCas9	negative selection	8405397
11111602	11111625	19	+	27260156	PANC0813	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.09664874278380009	[334]	[453,388,252,381]	-1	hSpCas9	negative selection	8405398
11107447	11107470	19	-	27260156	PANC0813	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.45861633618759035	[1969]	[1535,1845,1569,1761]	-6	hSpCas9	negative selection	8405399
11110704	11110727	19	-	27260156	RDES	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.7019538637732485	[64]	[69,119,148,162]	9	hSpCas9	negative selection	8462392
11110750	11110773	19	+	27260156	RDES	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.229625478693511	[514]	[437,413,572,623]	-4	hSpCas9	negative selection	8462393
11111509	11111532	19	+	27260156	RDES	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.19754259845882838	[1118]	[1178,1384,1597,1827]	3	hSpCas9	negative selection	8462394
11107500	11107523	19	-	27260156	RDES	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.3806755124594864	[695]	[569,473,666,778]	-6	hSpCas9	negative selection	8526648
11111602	11111625	19	+	27260156	RDES	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.6978474015712904	[334]	[161,296,230,267]	-8	hSpCas9	negative selection	8526649
11107447	11107470	19	-	27260156	RDES	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.22286174591958052	[1969]	[1437,1902,2243,2302]	-4	hSpCas9	negative selection	8526650
11110704	11110727	19	-	27260156	PC3	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.17930546377792123	[64]	[57,42,176,54]	4	hSpCas9	negative selection	8583643
11110750	11110773	19	+	27260156	PC3	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.25726352579881906	[514]	[270,418,488,596]	-5	hSpCas9	negative selection	8583644
11111509	11111532	19	+	27260156	PC3	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.026527039080781245	[1118]	[858,833,2006,1021]	0	hSpCas9	negative selection	8583645
11107500	11107523	19	-	27260156	PC3	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.14981475075087808	[695]	[437,619,930,646]	-3	hSpCas9	negative selection	8647899
11111602	11111625	19	+	27260156	PC3	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.3266164168658605	[334]	[149,195,555,309]	-6	hSpCas9	negative selection	8647900
11107447	11107470	19	-	27260156	PC3	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.3579665268073906	[1969]	[1050,1556,2388,1510]	-7	hSpCas9	negative selection	8647901
11110704	11110727	19	-	27260156	PATU8988T	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.0987018907838979	[64]	[48,96,8,121]	1	hSpCas9	negative selection	8704894
11110750	11110773	19	+	27260156	PATU8988T	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.3657871345538381	[514]	[780,469,535,773]	6	hSpCas9	negative selection	8704895
11111509	11111532	19	+	27260156	PATU8988T	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.47075251908432936	[1118]	[1325,1686,1658,1322]	7	hSpCas9	negative selection	8704896
11107500	11107523	19	-	27260156	PATU8988T	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	0.5116286104914879	[695]	[748,941,1135,1007]	8	hSpCas9	negative selection	8769150
11111602	11111625	19	+	27260156	PATU8988T	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	0.13710916406970075	[334]	[348,286,428,350]	2	hSpCas9	negative selection	8769151
11107447	11107470	19	-	27260156	PATU8988T	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.1364438766774969	[1969]	[1935,1603,1470,1922]	-2	hSpCas9	negative selection	8769152
11110704	11110727	19	-	27260156	T47D	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.0540713964862829	[64]	[131,81,47,51]	1	hSpCas9	negative selection	8826145
11110750	11110773	19	+	27260156	T47D	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.2500441726709691	[514]	[523,443,558,494]	-5	hSpCas9	negative selection	8826146
11111509	11111532	19	+	27260156	T47D	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.1444946706505139	[1118]	[1489,1351,1497,1429]	3	hSpCas9	negative selection	8826147
11107500	11107523	19	-	27260156	T47D	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.007173614732621902	[695]	[724,842,843,810]	0	hSpCas9	negative selection	8890401
11111602	11111625	19	+	27260156	T47D	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.39265559377905146	[334]	[274,245,336,335]	-7	hSpCas9	negative selection	8890402
11107447	11107470	19	-	27260156	T47D	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.2646248252684038	[1969]	[1871,1751,1880,2157]	-5	hSpCas9	negative selection	8890403
11110704	11110727	19	-	27260156	SU8686	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.41252363648747936	[64]	[129,51,32,132]	7	hSpCas9	negative selection	8947396
11110750	11110773	19	+	27260156	SU8686	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.029187842616659104	[514]	[573,394,551,579]	0	hSpCas9	negative selection	8947397
11111509	11111532	19	+	27260156	SU8686	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.33270995750416255	[1118]	[1137,1328,1525,1671]	5	hSpCas9	negative selection	8947398
11107500	11107523	19	-	27260156	SU8686	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.12133139142115279	[695]	[720,611,459,745]	-2	hSpCas9	negative selection	9011652
11111602	11111625	19	+	27260156	SU8686	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.6179411299130856	[334]	[160,243,193,276]	-7	hSpCas9	negative selection	9011653
11107447	11107470	19	-	27260156	SU8686	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.29210615135710083	[1969]	[1376,1378,1874,1837]	-5	hSpCas9	negative selection	9011654
11110704	11110727	19	-	27260156	SKES1	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.058896618894463515	[64]	[54,52,33,99]	-1	hSpCas9	negative selection	9068647
11110750	11110773	19	+	27260156	SKES1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.3066080258182684	[514]	[411,469,357,422]	-6	hSpCas9	negative selection	9068648
11111509	11111532	19	+	27260156	SKES1	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.06172159389541099	[1118]	[1209,1073,1065,950]	-1	hSpCas9	negative selection	9068649
11107500	11107523	19	-	27260156	SKES1	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.007762369351218323	[695]	[540,1041,651,557]	0	hSpCas9	negative selection	9132903
11111602	11111625	19	+	27260156	SKES1	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.10300442851237657	[334]	[260,383,199,389]	-2	hSpCas9	negative selection	9132904
11107447	11107470	19	-	27260156	SKES1	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.22343580260051787	[1969]	[1927,1470,1851,1492]	-5	hSpCas9	negative selection	9132905
11110704	11110727	19	-	27260156	TOV112D	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	-0.22244815122033712	[64]	[65,17,50,78]	-4	hSpCas9	negative selection	9189898
11110750	11110773	19	+	27260156	TOV112D	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.049185787483288196	[514]	[382,709,315,622]	-1	hSpCas9	negative selection	9189899
11111509	11111532	19	+	27260156	TOV112D	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	-0.17464761764660786	[1118]	[1201,1094,980,741]	-3	hSpCas9	negative selection	9189900
11107500	11107523	19	-	27260156	TOV112D	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.27800699512650107	[695]	[750,697,472,425]	-5	hSpCas9	negative selection	9254154
11111602	11111625	19	+	27260156	TOV112D	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	0.29325498274327627	[334]	[262,532,402,460]	5	hSpCas9	negative selection	9254155
11107447	11107470	19	-	27260156	TOV112D	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.19545968392932234	[1969]	[1634,2091,1712,1537]	-4	hSpCas9	negative selection	9254156
11110704	11110727	19	-	27260156	TC71	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.37141849833801777	[64]	[41,120,127,67]	8	hSpCas9	negative selection	9311149
11110750	11110773	19	+	27260156	TC71	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.12301868043574381	[514]	[627,525,462,402]	-3	hSpCas9	negative selection	9311150
11111509	11111532	19	+	27260156	TC71	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.02285055332559205	[1118]	[1290,1108,1339,1122]	0	hSpCas9	negative selection	9311151
11107500	11107523	19	-	27260156	TC71	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.016593114479761195	[695]	[688,754,789,713]	0	hSpCas9	negative selection	9375405
11111602	11111625	19	+	27260156	TC71	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.13681589059469468	[334]	[400,291,306,303]	-4	hSpCas9	negative selection	9375406
11107447	11107470	19	-	27260156	TC71	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.23447054533969247	[1969]	[1852,1596,1709,2035]	-6	hSpCas9	negative selection	9375407
11110704	11110727	19	-	27260156	TC32	viability	GGCACTCGTAGCCGATCTTAAGG	LDLR	ENSG00000130164	0.33243065133028926	[64]	[77,42,112,88]	6	hSpCas9	negative selection	9432400
11110750	11110773	19	+	27260156	TC32	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.3535845782890042	[514]	[375,235,463,492]	-6	hSpCas9	negative selection	9432401
11111509	11111532	19	+	27260156	TC32	viability	TCCAGATATCGATGAGTGTCAGG	LDLR	ENSG00000130164	0.03596769521555521	[1118]	[1099,922,1279,1028]	0	hSpCas9	negative selection	9432402
11107500	11107523	19	-	27260156	TC32	viability	AGACTCACCGCACTCTTTGATGG	LDLR	ENSG00000130164	-0.07408681713378223	[695]	[497,574,785,650]	-1	hSpCas9	negative selection	9496656
11111602	11111625	19	+	27260156	TC32	viability	CCAGCTGGACCCCCACACGAAGG	LDLR	ENSG00000130164	-0.651703797649685	[334]	[180,139,265,241]	-8	hSpCas9	negative selection	9496657
11107447	11107470	19	-	27260156	TC32	viability	CCATGTTGCAGACTTTGTCCAGG	LDLR	ENSG00000130164	-0.23304210435922212	[1969]	[1631,1416,1817,1416]	-4	hSpCas9	negative selection	9496658
11100265	11100288	19	+	27869803	HPAFII	viability after 27 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.3485672199857337	[351]	[269,206,NaN]	3	hSpCas9	negative selection	9565481
11102704	11102727	19	-	27869803	HPAFII	viability after 27 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.9020620910101769	[139]	[76,187,NaN]	7	hSpCas9	negative selection	9565482
11105280	11105303	19	+	27869803	HPAFII	viability after 27 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.031228218561112686	[154]	[73,90,NaN]	0	hSpCas9	negative selection	9565483
11106574	11106597	19	-	27869803	HPAFII	viability after 27 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.2994050782612231	[428]	[233,140,NaN]	-2	hSpCas9	negative selection	9565484
11107385	11107408	19	+	27869803	HPAFII	viability after 27 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-1.9793101412328151	[464]	[49,71,NaN]	-8	hSpCas9	negative selection	9565485
11110660	11110683	19	+	27869803	HPAFII	viability after 27 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.04838892621715902	[254]	[40,219,NaN]	0	hSpCas9	negative selection	9565486
11100265	11100288	19	+	27869803	HPAFII	viability after 15 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.18010235742860758	[351]	[665,280,NaN]	2	hSpCas9	negative selection	9647930
11102704	11102727	19	-	27869803	HPAFII	viability after 15 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.6324705061955083	[139]	[223,238,NaN]	7	hSpCas9	negative selection	9647931
11105280	11105303	19	+	27869803	HPAFII	viability after 15 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.1691383394110123	[154]	[227,161,NaN]	2	hSpCas9	negative selection	9647932
11106574	11106597	19	-	27869803	HPAFII	viability after 15 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.3412796028079327	[428]	[358,366,NaN]	-4	hSpCas9	negative selection	9647933
11107385	11107408	19	+	27869803	HPAFII	viability after 15 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-0.4519753279321759	[464]	[582,229,NaN]	-5	hSpCas9	negative selection	9647934
11110660	11110683	19	+	27869803	HPAFII	viability after 15 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.3503957154666172	[254]	[156,250,NaN]	-4	hSpCas9	negative selection	9647935
11100265	11100288	19	+	27869803	ASPC1	viability after 36 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.6248323709616087	[998]	[352,326,828]	6	hSpCas9	negative selection	9730379
11102704	11102727	19	-	27869803	ASPC1	viability after 36 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	0.5459963182869934	[413]	[485,104,99]	5	hSpCas9	negative selection	9730380
11105280	11105303	19	+	27869803	ASPC1	viability after 36 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.7120839225110238	[376]	[135,114,348]	7	hSpCas9	negative selection	9730381
11106574	11106597	19	-	27869803	ASPC1	viability after 36 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.3220510457193754	[957]	[693,465,181]	3	hSpCas9	negative selection	9730382
11107385	11107408	19	+	27869803	ASPC1	viability after 36 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-1.6815836180680437	[1122]	[146,74,140]	-9	hSpCas9	negative selection	9730383
11110660	11110683	19	+	27869803	ASPC1	viability after 36 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-2.053860515929772	[764]	[32,54,92]	-9	hSpCas9	negative selection	9730384
11100265	11100288	19	+	27869803	PATU8988S	viability after 35 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.5183710129139023	[995]	[305,253,NaN]	-5	hSpCas9	negative selection	9812828
11102704	11102727	19	-	27869803	PATU8988S	viability after 35 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-1.7998074959591546	[310]	[24,46,NaN]	-8	hSpCas9	negative selection	9812829
11105280	11105303	19	+	27869803	PATU8988S	viability after 35 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.26529429389568265	[352]	[114,226,NaN]	3	hSpCas9	negative selection	9812830
11106574	11106597	19	-	27869803	PATU8988S	viability after 35 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.0006596369612470454	[804]	[263,384,NaN]	0	hSpCas9	negative selection	9812831
11107385	11107408	19	+	27869803	PATU8988S	viability after 35 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.2701486100103343	[1065]	[405,629,NaN]	3	hSpCas9	negative selection	9812832
11110660	11110683	19	+	27869803	PATU8988S	viability after 35 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.45707957761332824	[526]	[204,103,NaN]	-5	hSpCas9	negative selection	9812833
11100265	11100288	19	+	27869803	PATU8988S	viability after 31 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.7748065893481331	[995]	[232,230,NaN]	-7	hSpCas9	negative selection	9895277
11102704	11102727	19	-	27869803	PATU8988S	viability after 31 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	-0.9900118321046905	[310]	[39,90,NaN]	-7	hSpCas9	negative selection	9895278
11105280	11105303	19	+	27869803	PATU8988S	viability after 31 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	-0.2594409011504414	[352]	[66,181,NaN]	-3	hSpCas9	negative selection	9895279
11106574	11106597	19	-	27869803	PATU8988S	viability after 31 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	0.31253009160945056	[804]	[351,457,NaN]	4	hSpCas9	negative selection	9895280
11107385	11107408	19	+	27869803	PATU8988S	viability after 31 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	0.166355215875035	[1065]	[337,653,NaN]	2	hSpCas9	negative selection	9895281
11110660	11110683	19	+	27869803	PATU8988S	viability after 31 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.1890897815846652	[526]	[204,157,NaN]	-2	hSpCas9	negative selection	9895282
11100265	11100288	19	+	27869803	HPAFII	viability after 35 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	-0.09767361687599962	[351]	[174,156,NaN]	0	hSpCas9	negative selection	9977726
11102704	11102727	19	-	27869803	HPAFII	viability after 35 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	1.0894720883702744	[139]	[20,296,NaN]	7	hSpCas9	negative selection	9977727
11105280	11105303	19	+	27869803	HPAFII	viability after 35 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.6501929757527711	[154]	[61,191,NaN]	4	hSpCas9	negative selection	9977728
11106574	11106597	19	-	27869803	HPAFII	viability after 35 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.34596027125673484	[428]	[152,190,NaN]	-2	hSpCas9	negative selection	9977729
11107385	11107408	19	+	27869803	HPAFII	viability after 35 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-1.638291851706723	[464]	[21,135,NaN]	-7	hSpCas9	negative selection	9977730
11110660	11110683	19	+	27869803	HPAFII	viability after 35 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.14825006467461493	[254]	[28,214,NaN]	-1	hSpCas9	negative selection	9977731
11100265	11100288	19	+	27869803	HPAFII	viability after 31 days	GGAAATGCATCTCCTACAAGTGG	LDLR	ENSG00000130164	0.061340261140810814	[351]	[275,129,NaN]	0	hSpCas9	negative selection	10060175
11102704	11102727	19	-	27869803	HPAFII	viability after 31 days	GAGGAATGCAGCGGTTGACACGG	LDLR	ENSG00000130164	1.1679628238883268	[139]	[76,284,NaN]	8	hSpCas9	negative selection	10060176
11105280	11105303	19	+	27869803	HPAFII	viability after 31 days	AGTTCGTCTGTGACTCAGACCGG	LDLR	ENSG00000130164	0.3977999466252236	[154]	[49,184,NaN]	3	hSpCas9	negative selection	10060177
11106574	11106597	19	-	27869803	HPAFII	viability after 31 days	CTGGAATTCGTCAGGGCGACAGG	LDLR	ENSG00000130164	-0.8436057681671071	[428]	[148,117,NaN]	-5	hSpCas9	negative selection	10060178
11107385	11107408	19	+	27869803	HPAFII	viability after 31 days	CTCACAGTGACACTCTGCGAGGG	LDLR	ENSG00000130164	-1.8862653979916748	[464]	[27,116,NaN]	-8	hSpCas9	negative selection	10060179
11110660	11110683	19	+	27869803	HPAFII	viability after 31 days	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.10376407746756316	[254]	[58,213,NaN]	0	hSpCas9	negative selection	10060180
11110660	11110683	19	+	28162770	P31FUJ	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.7588710160819663	[215]	[149]	-5	hSpCas9	negative selection	10183707
11123207	11123230	19	-	28162770	P31FUJ	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.9571677618009512	[379]	[229]	-6	hSpCas9	negative selection	10183708
11113281	11113304	19	-	28162770	P31FUJ	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.21592838584998253	[84]	[85]	-2	hSpCas9	negative selection	10183709
11089540	11089563	19	+	28162770	P31FUJ	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	-0.6349006479857243	[221]	[167]	-5	hSpCas9	negative selection	10183710
11089556	11089579	19	+	28162770	P31FUJ	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.15325622789269921	[87]	[114]	1	hSpCas9	negative selection	10183711
11110750	11110773	19	+	28162770	P31FUJ	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.4816227510284717	[201]	[169]	-4	hSpCas9	negative selection	10183712
11111548	11111571	19	+	28162770	P31FUJ	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-0.4726292190868471	[110]	[93]	-4	hSpCas9	negative selection	10183713
11113350	11113373	19	+	28162770	P31FUJ	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.3505241632874734	[803]	[740]	-3	hSpCas9	negative selection	10183714
11113378	11113401	19	+	28162770	P31FUJ	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-1.2749716586583182	[242]	[117]	-7	hSpCas9	negative selection	10183715
11113738	11113761	19	-	28162770	P31FUJ	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.9264709645780347	[371]	[229]	-6	hSpCas9	negative selection	10183716
11110660	11110683	19	+	28162770	TF1	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	NaN	[NaN]	[34]	1	hSpCas9	negative selection	10353073
11123207	11123230	19	-	28162770	TF1	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	NaN	[NaN]	[155]	1	hSpCas9	negative selection	10353074
11113281	11113304	19	-	28162770	TF1	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10353075
11089540	11089563	19	+	28162770	TF1	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	NaN	[NaN]	[149]	1	hSpCas9	negative selection	10353076
11089556	11089579	19	+	28162770	TF1	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	NaN	[NaN]	[104]	1	hSpCas9	negative selection	10353077
11110750	11110773	19	+	28162770	TF1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	NaN	[NaN]	[138]	1	hSpCas9	negative selection	10353078
11111548	11111571	19	+	28162770	TF1	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	NaN	[NaN]	[125]	1	hSpCas9	negative selection	10353079
11113350	11113373	19	+	28162770	TF1	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	NaN	[NaN]	[447]	1	hSpCas9	negative selection	10353080
11113378	11113401	19	+	28162770	TF1	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	NaN	[NaN]	[95]	1	hSpCas9	negative selection	10353081
11113738	11113761	19	-	28162770	TF1	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	NaN	[NaN]	[182]	1	hSpCas9	negative selection	10353082
11110660	11110683	19	+	28162770	SKM1	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.019038545081559	[93]	[81]	-6	hSpCas9	negative selection	10522439
11123207	11123230	19	-	28162770	SKM1	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	0.2800964895967308	[74]	[160]	2	hSpCas9	negative selection	10522440
11113281	11113304	19	-	28162770	SKM1	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-1.3195013574928223	[23]	[16]	-7	hSpCas9	negative selection	10522441
11089540	11089563	19	+	28162770	SKM1	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.34197403708912055	[53]	[120]	3	hSpCas9	negative selection	10522442
11089556	11089579	19	+	28162770	SKM1	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.8858175504846842	[29]	[97]	8	hSpCas9	negative selection	10522443
11110750	11110773	19	+	28162770	SKM1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.2210976534318277	[59]	[90]	-2	hSpCas9	negative selection	10522444
11111548	11111571	19	+	28162770	SKM1	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-0.2193371955673904	[26]	[40]	-2	hSpCas9	negative selection	10522445
11113350	11113373	19	+	28162770	SKM1	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.5883293518195547	[181]	[213]	-5	hSpCas9	negative selection	10522446
11113378	11113401	19	+	28162770	SKM1	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.3625700793847082	[31]	[43]	-3	hSpCas9	negative selection	10522447
11113738	11113761	19	-	28162770	SKM1	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.03221940541235127	[58]	[101]	0	hSpCas9	negative selection	10522448
11110660	11110683	19	+	28162770	SKM1	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.019038545081559	[93]	[81]	-6	hSpCas9	negative selection	10691805
11123207	11123230	19	-	28162770	SKM1	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	0.2800964895967308	[74]	[160]	2	hSpCas9	negative selection	10691806
11113281	11113304	19	-	28162770	SKM1	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-1.3195013574928223	[23]	[16]	-7	hSpCas9	negative selection	10691807
11089540	11089563	19	+	28162770	SKM1	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.34197403708912055	[53]	[120]	3	hSpCas9	negative selection	10691808
11089556	11089579	19	+	28162770	SKM1	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.8858175504846842	[29]	[97]	8	hSpCas9	negative selection	10691809
11110750	11110773	19	+	28162770	SKM1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.2210976534318277	[59]	[90]	-2	hSpCas9	negative selection	10691810
11111548	11111571	19	+	28162770	SKM1	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-0.2193371955673904	[26]	[40]	-2	hSpCas9	negative selection	10691811
11113350	11113373	19	+	28162770	SKM1	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.5883293518195547	[181]	[213]	-5	hSpCas9	negative selection	10691812
11113378	11113401	19	+	28162770	SKM1	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.3625700793847082	[31]	[43]	-3	hSpCas9	negative selection	10691813
11113738	11113761	19	-	28162770	SKM1	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.03221940541235127	[58]	[101]	0	hSpCas9	negative selection	10691814
11110660	11110683	19	+	28162770	PL21	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.9965982180869589	[352]	[76]	-6	hSpCas9	negative selection	10861171
11123207	11123230	19	-	28162770	PL21	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-1.5433688255436582	[220]	[32]	-7	hSpCas9	negative selection	10861172
11113281	11113304	19	-	28162770	PL21	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	0.2652346427112051	[64]	[33]	2	hSpCas9	negative selection	10861173
11089540	11089563	19	+	28162770	PL21	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	-1.600551577287273	[215]	[30]	-7	hSpCas9	negative selection	10861174
11089556	11089579	19	+	28162770	PL21	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.24320833638120587	[98]	[50]	2	hSpCas9	negative selection	10861175
11110750	11110773	19	+	28162770	PL21	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.5281870614030134	[221]	[66]	-4	hSpCas9	negative selection	10861176
11111548	11111571	19	+	28162770	PL21	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-2.3234223415676927	[68]	[5]	-8	hSpCas9	negative selection	10861177
11113350	11113373	19	+	28162770	PL21	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.7825823940788443	[663]	[167]	-5	hSpCas9	negative selection	10861178
11113378	11113401	19	+	28162770	PL21	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.6596827274624194	[97]	[26]	-4	hSpCas9	negative selection	10861179
11113738	11113761	19	-	28162770	PL21	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	0.019909604655269253	[280]	[123]	0	hSpCas9	negative selection	10861180
11110660	11110683	19	+	28162770	P31FUJ	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.7588710160819663	[215]	[149]	-5	hSpCas9	negative selection	11030537
11123207	11123230	19	-	28162770	P31FUJ	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.9571677618009512	[379]	[229]	-6	hSpCas9	negative selection	11030538
11113281	11113304	19	-	28162770	P31FUJ	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.21592838584998253	[84]	[85]	-2	hSpCas9	negative selection	11030539
11089540	11089563	19	+	28162770	P31FUJ	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	-0.6349006479857243	[221]	[167]	-5	hSpCas9	negative selection	11030540
11089556	11089579	19	+	28162770	P31FUJ	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.15325622789269921	[87]	[114]	1	hSpCas9	negative selection	11030541
11110750	11110773	19	+	28162770	P31FUJ	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.4816227510284717	[201]	[169]	-4	hSpCas9	negative selection	11030542
11111548	11111571	19	+	28162770	P31FUJ	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-0.4726292190868471	[110]	[93]	-4	hSpCas9	negative selection	11030543
11113350	11113373	19	+	28162770	P31FUJ	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.3505241632874734	[803]	[740]	-3	hSpCas9	negative selection	11030544
11113378	11113401	19	+	28162770	P31FUJ	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-1.2749716586583182	[242]	[117]	-7	hSpCas9	negative selection	11030545
11113738	11113761	19	-	28162770	P31FUJ	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.9264709645780347	[371]	[229]	-6	hSpCas9	negative selection	11030546
11110660	11110683	19	+	28162770	OCIAML5	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-3.8744343838924515	[194]	[23]	-9	hSpCas9	negative selection	11199903
11123207	11123230	19	-	28162770	OCIAML5	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.39727136234741844	[169]	[232]	-3	hSpCas9	negative selection	11199904
11113281	11113304	19	-	28162770	OCIAML5	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.2022529257928729	[57]	[90]	-1	hSpCas9	negative selection	11199905
11089540	11089563	19	+	28162770	OCIAML5	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.21278457348597093	[86]	[181]	1	hSpCas9	negative selection	11199906
11089556	11089579	19	+	28162770	OCIAML5	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	-0.8188997069287975	[85]	[87]	-5	hSpCas9	negative selection	11199907
11110750	11110773	19	+	28162770	OCIAML5	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.31919258129129496	[93]	[135]	-2	hSpCas9	negative selection	11199908
11111548	11111571	19	+	28162770	OCIAML5	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-0.04820909304262	[58]	[102]	0	hSpCas9	negative selection	11199909
11113350	11113373	19	+	28162770	OCIAML5	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.8327012459970659	[369]	[374]	-5	hSpCas9	negative selection	11199910
11113378	11113401	19	+	28162770	OCIAML5	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.34642652280424635	[80]	[114]	-2	hSpCas9	negative selection	11199911
11113738	11113761	19	-	28162770	OCIAML5	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-1.1643444957176399	[148]	[119]	-6	hSpCas9	negative selection	11199912
11110660	11110683	19	+	28162770	EOL1	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.18214142857941695	[490]	[227]	-1	hSpCas9	negative selection	11369269
11123207	11123230	19	-	28162770	EOL1	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-1.4560562306444353	[275]	[52]	-7	hSpCas9	negative selection	11369270
11113281	11113304	19	-	28162770	EOL1	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.2453772298717778	[143]	[63]	-2	hSpCas9	negative selection	11369271
11089540	11089563	19	+	28162770	EOL1	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	-0.996521759207746	[408]	[107]	-6	hSpCas9	negative selection	11369272
11089556	11089579	19	+	28162770	EOL1	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	1.158037901790313	[147]	[173]	8	hSpCas9	negative selection	11369273
11110750	11110773	19	+	28162770	EOL1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.5594435354813905	[406]	[315]	5	hSpCas9	negative selection	11369274
11111548	11111571	19	+	28162770	EOL1	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-1.2106118117111013	[122]	[27]	-7	hSpCas9	negative selection	11369275
11113350	11113373	19	+	28162770	EOL1	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.42130616256230813	[759]	[298]	-3	hSpCas9	negative selection	11369276
11113378	11113401	19	+	28162770	EOL1	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	0.4676900965970635	[139]	[101]	4	hSpCas9	negative selection	11369277
11113738	11113761	19	-	28162770	EOL1	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.5416684516338723	[372]	[134]	-4	hSpCas9	negative selection	11369278
11110660	11110683	19	+	28162770	MOLM13	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.9140860970127225	[416]	[79]	-7	hSpCas9	negative selection	11538635
11123207	11123230	19	-	28162770	MOLM13	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-2.5487893596020514	[347]	[42]	-8	hSpCas9	negative selection	11538636
11113281	11113304	19	-	28162770	MOLM13	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.14283621524165935	[112]	[73]	-1	hSpCas9	negative selection	11538637
11089540	11089563	19	+	28162770	MOLM13	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.12908746809282035	[257]	[203]	0	hSpCas9	negative selection	11538638
11089556	11089579	19	+	28162770	MOLM13	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	1.0153771768470723	[129]	[189]	7	hSpCas9	negative selection	11538639
11110750	11110773	19	+	28162770	MOLM13	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	1.017157457857667	[340]	[498]	7	hSpCas9	negative selection	11538640
11111548	11111571	19	+	28162770	MOLM13	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-0.5716389826420588	[147]	[71]	-3	hSpCas9	negative selection	11538641
11113350	11113373	19	+	28162770	MOLM13	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.7665758720924443	[759]	[322]	-4	hSpCas9	negative selection	11538642
11113378	11113401	19	+	28162770	MOLM13	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	0.20299223169359537	[154]	[128]	1	hSpCas9	negative selection	11538643
11113738	11113761	19	-	28162770	MOLM13	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.1331601033442138	[495]	[326]	-1	hSpCas9	negative selection	11538644
11110660	11110683	19	+	28162770	HEL	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-1.4809355383861984	[352]	[80]	-7	hSpCas9	negative selection	11708001
11123207	11123230	19	-	28162770	HEL	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-2.7632535276754804	[317]	[29]	-8	hSpCas9	negative selection	11708002
11113281	11113304	19	-	28162770	HEL	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.9166885766136619	[111]	[37]	-5	hSpCas9	negative selection	11708003
11089540	11089563	19	+	28162770	HEL	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	-0.9702380448903959	[259]	[84]	-6	hSpCas9	negative selection	11708004
11089556	11089579	19	+	28162770	HEL	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.48354023715110295	[133]	[119]	4	hSpCas9	negative selection	11708005
11110750	11110773	19	+	28162770	HEL	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.9061544140132773	[236]	[80]	-5	hSpCas9	negative selection	11708006
11111548	11111571	19	+	28162770	HEL	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-2.5924776296936747	[112]	[11]	-8	hSpCas9	negative selection	11708007
11113350	11113373	19	+	28162770	HEL	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-1.7576383605723551	[717]	[135]	-7	hSpCas9	negative selection	11708008
11113378	11113401	19	+	28162770	HEL	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.009337864579336386	[142]	[90]	0	hSpCas9	negative selection	11708009
11113738	11113761	19	-	28162770	HEL	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-1.9871202066951223	[358]	[57]	-8	hSpCas9	negative selection	11708010
11110660	11110683	19	+	28162770	MV411	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.2701696821366162	[271]	[189]	-2	hSpCas9	negative selection	11877367
11123207	11123230	19	-	28162770	MV411	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	1.005161705115779	[206]	[349]	8	hSpCas9	negative selection	11877368
11113281	11113304	19	-	28162770	MV411	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.040543212181249344	[104]	[85]	0	hSpCas9	negative selection	11877369
11089540	11089563	19	+	28162770	MV411	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.31352674124054775	[255]	[267]	2	hSpCas9	negative selection	11877370
11089556	11089579	19	+	28162770	MV411	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	1.0329330388766402	[75]	[130]	8	hSpCas9	negative selection	11877371
11110750	11110773	19	+	28162770	MV411	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.5426352800556159	[206]	[253]	5	hSpCas9	negative selection	11877372
11111548	11111571	19	+	28162770	MV411	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	0.11533401477543026	[79]	[72]	1	hSpCas9	negative selection	11877373
11113350	11113373	19	+	28162770	MV411	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	0.18173430373194566	[583]	[557]	1	hSpCas9	negative selection	11877374
11113378	11113401	19	+	28162770	MV411	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-1.0529573825549459	[132]	[53]	-6	hSpCas9	negative selection	11877375
11113738	11113761	19	-	28162770	MV411	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.6720725313568567	[243]	[128]	-5	hSpCas9	negative selection	11877376
11110660	11110683	19	+	28162770	MONOMAC1	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	0.08218679687357044	[191]	[232]	0	hSpCas9	negative selection	12046733
11123207	11123230	19	-	28162770	MONOMAC1	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.33030337792301784	[135]	[123]	-3	hSpCas9	negative selection	12046734
11113281	11113304	19	-	28162770	MONOMAC1	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-1.9746444257231057	[71]	[20]	-8	hSpCas9	negative selection	12046735
11089540	11089563	19	+	28162770	MONOMAC1	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.5238090817433756	[107]	[177]	5	hSpCas9	negative selection	12046736
11089556	11089579	19	+	28162770	MONOMAC1	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.42889743471790853	[80]	[124]	4	hSpCas9	negative selection	12046737
11110750	11110773	19	+	28162770	MONOMAC1	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.9608756366807791	[133]	[298]	8	hSpCas9	negative selection	12046738
11111548	11111571	19	+	28162770	MONOMAC1	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-0.5662706567252727	[61]	[47]	-5	hSpCas9	negative selection	12046739
11113350	11113373	19	+	28162770	MONOMAC1	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	0.002611618620604661	[410]	[471]	0	hSpCas9	negative selection	12046740
11113378	11113401	19	+	28162770	MONOMAC1	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	-0.021465282476099246	[84]	[95]	0	hSpCas9	negative selection	12046741
11113738	11113761	19	-	28162770	MONOMAC1	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	0.20029865048583118	[204]	[269]	2	hSpCas9	negative selection	12046742
11110660	11110683	19	+	28162770	OCIAML2	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.9256337318386498	[60]	[177]	-6	hSpCas9	negative selection	12216099
11123207	11123230	19	-	28162770	OCIAML2	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	-0.10051819684483349	[52]	[273]	-1	hSpCas9	negative selection	12216100
11113281	11113304	19	-	28162770	OCIAML2	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-0.9852029980719195	[19]	[55]	-6	hSpCas9	negative selection	12216101
11089540	11089563	19	+	28162770	OCIAML2	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	0.37736708131278884	[34]	[251]	3	hSpCas9	negative selection	12216102
11089556	11089579	19	+	28162770	OCIAML2	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.4469080145658658	[17]	[135]	4	hSpCas9	negative selection	12216103
11110750	11110773	19	+	28162770	OCIAML2	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	0.26845582079841446	[33]	[226]	2	hSpCas9	negative selection	12216104
11111548	11111571	19	+	28162770	OCIAML2	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	1.3748602257022138	[7]	[114]	9	hSpCas9	negative selection	12216105
11113350	11113373	19	+	28162770	OCIAML2	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.29595129382921415	[100]	[455]	-2	hSpCas9	negative selection	12216106
11113378	11113401	19	+	28162770	OCIAML2	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	0.4362607703663572	[25]	[194]	4	hSpCas9	negative selection	12216107
11113738	11113761	19	-	28162770	OCIAML2	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.7368039386065224	[45]	[152]	-5	hSpCas9	negative selection	12216108
11110660	11110683	19	+	28162770	OCIAML3	viability	GAATGCTTGGACAACAACGGCGG	LDLR	ENSG00000130164	-0.5769341269652217	[83]	[169]	-4	hSpCas9	negative selection	12385465
11123207	11123230	19	-	28162770	OCIAML3	viability	GCTGACCTTTAGCCTGACGGTGG	LDLR	ENSG00000130164	0.6445044463755616	[88]	[419]	6	hSpCas9	negative selection	12385466
11113281	11113304	19	-	28162770	OCIAML3	viability	GGTGAAGAAGAGGTAGGCGATGG	LDLR	ENSG00000130164	-1.049687124100353	[23]	[34]	-6	hSpCas9	negative selection	12385467
11089540	11089563	19	+	28162770	OCIAML3	viability	GCTGCGAGCATGGGGCCCTGGGG	LDLR	ENSG00000130164	-0.4156703990656507	[56]	[128]	-3	hSpCas9	negative selection	12385468
11089556	11089579	19	+	28162770	OCIAML3	viability	CCTGGGGCTGGAAATTGCGCTGG	LDLR	ENSG00000130164	0.5392588905393011	[30]	[135]	5	hSpCas9	negative selection	12385469
11110750	11110773	19	+	28162770	OCIAML3	viability	GTGGCCCAGCGAAGATGCGAAGG	LDLR	ENSG00000130164	-0.2779801468764852	[48]	[121]	-2	hSpCas9	negative selection	12385470
11111548	11111571	19	+	28162770	OCIAML3	viability	CCAGCTCTGCGTGAACCTGGAGG	LDLR	ENSG00000130164	-1.009045139603007	[27]	[41]	-6	hSpCas9	negative selection	12385471
11113350	11113373	19	+	28162770	OCIAML3	viability	CCAGCCTCATCCCCAACCTGAGG	LDLR	ENSG00000130164	-0.3527150136444357	[194]	[460]	-3	hSpCas9	negative selection	12385472
11113378	11113401	19	+	28162770	OCIAML3	viability	GGTCGCTCTGGACACGGAGGTGG	LDLR	ENSG00000130164	0.06591691807821509	[24]	[78]	0	hSpCas9	negative selection	12385473
11113738	11113761	19	-	28162770	OCIAML3	viability	ATGAACAGGATCCACCACGATGG	LDLR	ENSG00000130164	-0.7708854024082423	[77]	[137]	-5	hSpCas9	negative selection	12385474