Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:89884
• Symbol:LHX4
• Description:LIM homeobox 4

DataSource: http://genomecrispr.dkfz.de/#!/results/LHX4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
180248424	180248447	1	+	26472758	Jiyoye	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.1654694851125914	[187]	[158]	1	hSpCas9	negative selection	90391
180266524	180266547	1	+	26472758	Jiyoye	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	-0.6542251631582698	[95]	[45]	-5	hSpCas9	negative selection	90393
180230535	180230558	1	+	26472758	Jiyoye	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.26647651859613164	[225]	[204]	2	hSpCas9	negative selection	90397
180248281	180248304	1	+	26472758	Jiyoye	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-0.5848758653786358	[180]	[90]	-4	hSpCas9	negative selection	90398
180248382	180248405	1	+	26472758	Jiyoye	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	1.9921378822270288	[0]	[2]	8	hSpCas9	negative selection	90399
180266440	180266463	1	+	26472758	Jiyoye	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.7511297827232348	[51]	[65]	5	hSpCas9	negative selection	90400
180248424	180248447	1	+	26472758	KBM7	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.3183084588210585	[580,355]	[339,205]	3	hSpCas9	negative selection	281509
180266524	180266547	1	+	26472758	KBM7	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	-0.31827025260085884	[252,225]	[132,51]	-3	hSpCas9	negative selection	281511
180230535	180230558	1	+	26472758	KBM7	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.5938487305700227	[861,709]	[479,621]	6	hSpCas9	negative selection	281515
180248281	180248304	1	+	26472758	KBM7	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-0.20176072636749504	[451,478]	[138,238]	-2	hSpCas9	negative selection	281516
180248382	180248405	1	+	26472758	KBM7	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	2.29082470000745	[27,3]	[30,36]	9	hSpCas9	negative selection	281517
180266440	180266463	1	+	26472758	KBM7	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	1.2988715251891367	[228,108]	[125,245]	9	hSpCas9	negative selection	281518
180248424	180248447	1	+	26472758	Raji	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.00677959443519377	[192]	[44]	0	hSpCas9	negative selection	472627
180266524	180266547	1	+	26472758	Raji	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.8015751058495141	[88]	[35]	7	hSpCas9	negative selection	472629
180230535	180230558	1	+	26472758	Raji	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.5340557351358466	[493]	[165]	5	hSpCas9	negative selection	472633
180248281	180248304	1	+	26472758	Raji	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.17327147103005655	[213]	[55]	1	hSpCas9	negative selection	472634
180248382	180248405	1	+	26472758	Raji	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	3.6923460360947553	[0]	[2]	9	hSpCas9	negative selection	472635
180266440	180266463	1	+	26472758	Raji	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.08058347602988425	[162]	[39]	0	hSpCas9	negative selection	472636
180248424	180248447	1	+	26472758	K562	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.7719611125574399	[298]	[430]	6	hSpCas9	negative selection	663745
180266524	180266547	1	+	26472758	K562	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	-0.6156052629040974	[264]	[145]	-4	hSpCas9	negative selection	663747
180230535	180230558	1	+	26472758	K562	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.12570911143860208	[632]	[582]	0	hSpCas9	negative selection	663751
180248281	180248304	1	+	26472758	K562	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.06015140706499601	[416]	[366]	0	hSpCas9	negative selection	663752
180248382	180248405	1	+	26472758	K562	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	-0.13409289558728243	[12]	[9]	-1	hSpCas9	negative selection	663753
180266440	180266463	1	+	26472758	K562	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.7758657190606014	[118]	[171]	6	hSpCas9	negative selection	663754
180248387	180248410	1	+	26627737	DLD1	viability	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.011785078646307512	[305]	[78,49,149]	0	hSpCas9	negative selection	767848
180266487	180266510	1	+	26627737	DLD1	viability	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.08980155235812419	[482]	[212,88,123]	-1	hSpCas9	negative selection	767849
180248387	180248410	1	+	26627737	GBM cells	viability after 5 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	1.019666034346296	[62]	[86,49]	9	hSpCas9	negative selection	850163
180266487	180266510	1	+	26627737	GBM cells	viability after 5 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.3158996459540512	[184]	[111,134]	5	hSpCas9	negative selection	850164
180248387	180248410	1	+	26627737	GBM cells	viability after 13 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	1.0894068832181296	[62]	[96,52]	9	hSpCas9	negative selection	932478
180266487	180266510	1	+	26627737	GBM cells	viability after 13 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	1.0645630078608188	[184]	[231,191]	9	hSpCas9	negative selection	932479
180248387	180248410	1	+	26627737	GBM cells	viability after 21 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	1.567815424010769	[62]	[113,89]	9	hSpCas9	negative selection	1014793
180266487	180266510	1	+	26627737	GBM cells	viability after 21 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.2115236322190226	[184]	[130,102]	2	hSpCas9	negative selection	1014794
180248387	180248410	1	+	26627737	RPE1	viability after 9 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.41226697683354785	[447]	[228,131]	3	hSpCas9	negative selection	1097108
180266487	180266510	1	+	26627737	RPE1	viability after 9 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.2864094698421845	[924]	[412,275]	2	hSpCas9	negative selection	1097109
180248387	180248410	1	+	26627737	RPE1	viability after 12 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.5427913408080776	[447]	[220,126]	3	hSpCas9	negative selection	1179423
180266487	180266510	1	+	26627737	RPE1	viability after 12 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.03833490645594195	[924]	[292,187]	0	hSpCas9	negative selection	1179424
180248387	180248410	1	+	26627737	RPE1	viability after 15 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.4206720279583709	[447]	[140,49]	-3	hSpCas9	negative selection	1261738
180266487	180266510	1	+	26627737	RPE1	viability after 15 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.3971973714804856	[924]	[507,186]	2	hSpCas9	negative selection	1261739
180248387	180248410	1	+	26627737	RPE1	viability after 18 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.5378158660872536	[447]	[248,96]	3	hSpCas9	negative selection	1344053
180266487	180266510	1	+	26627737	RPE1	viability after 18 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.6262804828368147	[924]	[554,203]	4	hSpCas9	negative selection	1344054
180248387	180248410	1	+	26627737	HeLa	viability after 8 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.7336454515080373	[217]	[190,123,164]	6	hSpCas9	negative selection	1426368
180266487	180266510	1	+	26627737	HeLa	viability after 8 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.17263073184687205	[168]	[84,34,125]	1	hSpCas9	negative selection	1426369
180248387	180248410	1	+	26627737	HeLa	viability after 12 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.8998653643318169	[217]	[120,242,130]	7	hSpCas9	negative selection	1508683
180266487	180266510	1	+	26627737	HeLa	viability after 12 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	1.761064500688546	[168]	[214,156,345]	9	hSpCas9	negative selection	1508684
180248387	180248410	1	+	26627737	HeLa	viability after 15 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.39756665591554385	[217]	[55,69,76]	-3	hSpCas9	negative selection	1590998
180266487	180266510	1	+	26627737	HeLa	viability after 15 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	1.5282667543374928	[168]	[173,206,215]	8	hSpCas9	negative selection	1590999
180248387	180248410	1	+	26627737	HeLa	viability after 18 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.3816221275394499	[217]	[34,62,76]	-3	hSpCas9	negative selection	1673313
180266487	180266510	1	+	26627737	HeLa	viability after 18 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	1.4870599797348674	[168]	[102,174,215]	8	hSpCas9	negative selection	1673314
180248387	180248410	1	+	26627737	HCT116	viability after 6 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.9700313146679365	[579]	[244,141]	5	hSpCas9	negative selection	1755628
180266487	180266510	1	+	26627737	HCT116	viability after 6 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.19830151059349274	[526]	[155,25]	-1	hSpCas9	negative selection	1755629
180248387	180248410	1	+	26627737	HCT116	viability after 8 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.2858578142594559	[173]	[40,93,99]	-3	hSpCas9	negative selection	1837943
180266487	180266510	1	+	26627737	HCT116	viability after 8 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.23777254074183746	[312]	[225,137,245]	2	hSpCas9	negative selection	1837944
180248387	180248410	1	+	26627737	HCT116	viability after 9 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.2129096163860411	[579]	[203,77]	-1	hSpCas9	negative selection	1920258
180266487	180266510	1	+	26627737	HCT116	viability after 9 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.3375773656639124	[526]	[188,49]	-2	hSpCas9	negative selection	1920259
180248387	180248410	1	+	26627737	HCT116	viability after 12 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.5507287139638719	[173]	[93,82,7]	-5	hSpCas9	negative selection	2002573
180266487	180266510	1	+	26627737	HCT116	viability after 12 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.09625970669538593	[312]	[138,185,205]	1	hSpCas9	negative selection	2002574
180248387	180248410	1	+	26627737	HCT116	viability after 15 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.10976767946799082	[173]	[172,54,59]	-1	hSpCas9	negative selection	2084888
180266487	180266510	1	+	26627737	HCT116	viability after 15 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.09759097163702098	[312]	[156,164,249]	1	hSpCas9	negative selection	2084889
180248387	180248410	1	+	26627737	HCT116	viability after 18 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.3873056540187947	[173]	[206,87,32]	3	hSpCas9	negative selection	2167203
180266487	180266510	1	+	26627737	HCT116	viability after 18 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.16355269497949848	[312]	[125,156,228]	1	hSpCas9	negative selection	2167204
180230577	180230600	1	-	24336569	HL60	viability	TCGGCACACCTAGCATCTCCGGG	LHX4	ENSG00000121454	1.1717512441744518	[128]	[614]	8	hSpCas9	negative selection	2274661
180248291	180248314	1	-	24336569	HL60	viability	CTGGTTGCAGCCAGCGCACTGGG	LHX4	ENSG00000121454	-0.007463519185119338	[227]	[479]	0	hSpCas9	negative selection	2274662
180248301	180248324	1	+	24336569	HL60	viability	TGGCTGCAACCAGCACATCCTGG	LHX4	ENSG00000121454	-0.38958639599122846	[649]	[1049]	-3	hSpCas9	negative selection	2274663
180248310	180248333	1	-	24336569	HL60	viability	TGAACTTGTCCAGGATGTGCTGG	LHX4	ENSG00000121454	0.27912561462757113	[809]	[2079]	2	hSpCas9	negative selection	2274664
180248319	180248342	1	+	24336569	HL60	viability	CCTGGACAAGTTCATCCTGAAGG	LHX4	ENSG00000121454	-0.175679442246547	[434]	[814]	-1	hSpCas9	negative selection	2274665
180248325	180248348	1	+	24336569	HL60	viability	CAAGTTCATCCTGAAGGTCCTGG	LHX4	ENSG00000121454	1.1048926848324419	[387]	[1765]	8	hSpCas9	negative selection	2274666
180248334	180248357	1	-	24336569	HL60	viability	AGTGTCTGTCCAGGACCTTCAGG	LHX4	ENSG00000121454	-0.3885085513083785	[891]	[1441]	-3	hSpCas9	negative selection	2274667
180248343	180248366	1	-	24336569	HL60	viability	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	0.19669159222956045	[173]	[421]	2	hSpCas9	negative selection	2274668
180248366	180248389	1	-	24336569	HL60	viability	GCAGTCTGCACACTTGAGGCAGG	LHX4	ENSG00000121454	-0.7222798360835699	[473]	[607]	-6	hSpCas9	negative selection	2274669
180248379	180248402	1	+	24336569	HL60	viability	TGCAGACTGCCAGATGCAGCTGG	LHX4	ENSG00000121454	-1.176883665707579	[749]	[701]	-8	hSpCas9	negative selection	2274670
180230577	180230600	1	-	24336569	KBM7	viability	TCGGCACACCTAGCATCTCCGGG	LHX4	ENSG00000121454	0.12203533983883771	[377]	[1121]	1	hSpCas9	negative selection	2341838
180248291	180248314	1	-	24336569	KBM7	viability	CTGGTTGCAGCCAGCGCACTGGG	LHX4	ENSG00000121454	0.24553210802789605	[166]	[539]	2	hSpCas9	negative selection	2341839
180248301	180248324	1	+	24336569	KBM7	viability	TGGCTGCAACCAGCACATCCTGG	LHX4	ENSG00000121454	-0.33113307711745266	[457]	[992]	-3	hSpCas9	negative selection	2341840
180248310	180248333	1	-	24336569	KBM7	viability	TGAACTTGTCCAGGATGTGCTGG	LHX4	ENSG00000121454	-0.3361077193908072	[970]	[2097]	-3	hSpCas9	negative selection	2341841
180248319	180248342	1	+	24336569	KBM7	viability	CCTGGACAAGTTCATCCTGAAGG	LHX4	ENSG00000121454	0.6213158846621851	[183]	[771]	5	hSpCas9	negative selection	2341842
180248325	180248348	1	+	24336569	KBM7	viability	CAAGTTCATCCTGAAGGTCCTGG	LHX4	ENSG00000121454	-0.24894659880932957	[1066]	[2448]	-2	hSpCas9	negative selection	2341843
180248334	180248357	1	-	24336569	KBM7	viability	AGTGTCTGTCCAGGACCTTCAGG	LHX4	ENSG00000121454	0.8273036466514064	[479]	[2322]	7	hSpCas9	negative selection	2341844
180248343	180248366	1	-	24336569	KBM7	viability	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.6312911497212705	[183]	[323]	-5	hSpCas9	negative selection	2341845
180248366	180248389	1	-	24336569	KBM7	viability	GCAGTCTGCACACTTGAGGCAGG	LHX4	ENSG00000121454	0.24895153321808516	[397]	[1289]	2	hSpCas9	negative selection	2341846
180248379	180248402	1	+	24336569	KBM7	viability	TGCAGACTGCCAGATGCAGCTGG	LHX4	ENSG00000121454	-0.8427171383900215	[527]	[802]	-6	hSpCas9	negative selection	2341847
180264395	180264418	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACACACACACACACACACAGTAG	LHX4	ENSG00000121454	0.19128589643959537	[429,108]	[111,17]	0	dCas9-VP64	positive selection	2424197
180264395	180264418	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACACACACACACACACACAGTAG	LHX4	ENSG00000121454	-0.29192793722986554	[278,490]	[95,106]	-3	dCas9-VP64	positive selection	2519452
180248319	180248342	1	+	27260157	DLD1	viability	CCTGGACAAGTTCATCCTGAAGG	LHX4	ENSG00000121454	1.06819344595129	[]	[]	9	hSpCas9	negative selection	2573768
180248379	180248402	1	+	27260157	DLD1	viability	TGCAGACTGCCAGATGCAGCTGG	LHX4	ENSG00000121454	-0.00803743278539887	[]	[]	0	hSpCas9	negative selection	2573910
180248388	180248411	1	-	27260157	DLD1	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	1.12007795090496	[]	[]	9	hSpCas9	negative selection	2576114
180266449	180266472	1	-	27260157	DLD1	viability	AGACAAAGTCCTGGGCCTTGCGG	LHX4	ENSG00000121454	0.777195070093101	[]	[]	8	hSpCas9	negative selection	2576221
180230525	180230548	1	-	27260157	DLD1	viability	AGTCGCACTCTGCATCATCTCGG	LHX4	ENSG00000121454	0.431037347695989	[]	[]	7	hSpCas9	negative selection	2578463
180248291	180248314	1	-	27260157	DLD1	viability	CTGGTTGCAGCCAGCGCACTGGG	LHX4	ENSG00000121454	-0.550766889983626	[]	[]	-4	hSpCas9	negative selection	2582390
180248290	180248313	1	-	27260157	DLD1	viability	TGGTTGCAGCCAGCGCACTGGGG	LHX4	ENSG00000121454	-0.0438928430407704	[]	[]	0	hSpCas9	negative selection	2584032
180248334	180248357	1	-	27260157	DLD1	viability	AGTGTCTGTCCAGGACCTTCAGG	LHX4	ENSG00000121454	0.4852596095224	[]	[]	8	hSpCas9	negative selection	2585113
180266405	180266428	1	+	27260157	DLD1	viability	AAATGCACGGCCTGCCAGCAGGG	LHX4	ENSG00000121454	0.836132552142095	[]	[]	9	hSpCas9	negative selection	2587230
180248301	180248324	1	+	27260157	DLD1	viability	TGGCTGCAACCAGCACATCCTGG	LHX4	ENSG00000121454	0.0888773754481964	[]	[]	3	hSpCas9	negative selection	2605067
180248343	180248366	1	-	27260157	DLD1	viability	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	0.433034082083867	[]	[]	7	hSpCas9	negative selection	2607786
180248399	180248422	1	+	27260157	DLD1	viability	TGGCGGACAGGTGCTTCTCCAGG	LHX4	ENSG00000121454	1.00633709756662	[]	[]	9	hSpCas9	negative selection	2610504
180230577	180230600	1	-	27260157	DLD1	viability	TCGGCACACCTAGCATCTCCGGG	LHX4	ENSG00000121454	-0.491969161714744	[]	[]	-4	hSpCas9	negative selection	2614290
180248325	180248348	1	+	27260157	DLD1	viability	CAAGTTCATCCTGAAGGTCCTGG	LHX4	ENSG00000121454	0.306573262412358	[]	[]	4	hSpCas9	negative selection	2617459
180248366	180248389	1	-	27260157	DLD1	viability	GCAGTCTGCACACTTGAGGCAGG	LHX4	ENSG00000121454	0.568963400061184	[]	[]	8	hSpCas9	negative selection	2641121
180248336	180248359	1	+	27260157	DLD1	viability	TGAAGGTCCTGGACAGACACTGG	LHX4	ENSG00000121454	0.369725340532281	[]	[]	4	hSpCas9	negative selection	2642123
180248310	180248333	1	-	27260157	DLD1	viability	TGAACTTGTCCAGGATGTGCTGG	LHX4	ENSG00000121454	-0.680462382626253	[]	[]	-5	hSpCas9	negative selection	2649583
180248319	180248342	1	+	27260157	HT1080	viability	CCTGGACAAGTTCATCCTGAAGG	LHX4	ENSG00000121454	1.16824585506485	[]	[]	8	hSpCas9	negative selection	2649898
180248379	180248402	1	+	27260157	HT1080	viability	TGCAGACTGCCAGATGCAGCTGG	LHX4	ENSG00000121454	0.830907440398225	[]	[]	7	hSpCas9	negative selection	2650040
180248388	180248411	1	-	27260157	HT1080	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.958757961964016	[]	[]	7	hSpCas9	negative selection	2652244
180266449	180266472	1	-	27260157	HT1080	viability	AGACAAAGTCCTGGGCCTTGCGG	LHX4	ENSG00000121454	-0.00976658432686293	[]	[]	0	hSpCas9	negative selection	2652351
180230525	180230548	1	-	27260157	HT1080	viability	AGTCGCACTCTGCATCATCTCGG	LHX4	ENSG00000121454	0.212025447048911	[]	[]	2	hSpCas9	negative selection	2654593
180248291	180248314	1	-	27260157	HT1080	viability	CTGGTTGCAGCCAGCGCACTGGG	LHX4	ENSG00000121454	-0.621214662391506	[]	[]	-8	hSpCas9	negative selection	2658520
180248290	180248313	1	-	27260157	HT1080	viability	TGGTTGCAGCCAGCGCACTGGGG	LHX4	ENSG00000121454	-0.627580285333545	[]	[]	-8	hSpCas9	negative selection	2660162
180248334	180248357	1	-	27260157	HT1080	viability	AGTGTCTGTCCAGGACCTTCAGG	LHX4	ENSG00000121454	0.386515923455073	[]	[]	3	hSpCas9	negative selection	2661243
180266405	180266428	1	+	27260157	HT1080	viability	AAATGCACGGCCTGCCAGCAGGG	LHX4	ENSG00000121454	0.800023343346228	[]	[]	7	hSpCas9	negative selection	2663360
180248301	180248324	1	+	27260157	HT1080	viability	TGGCTGCAACCAGCACATCCTGG	LHX4	ENSG00000121454	0.478112330363369	[]	[]	4	hSpCas9	negative selection	2681197
180248343	180248366	1	-	27260157	HT1080	viability	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.472085767022321	[]	[]	-7	hSpCas9	negative selection	2683916
180248399	180248422	1	+	27260157	HT1080	viability	TGGCGGACAGGTGCTTCTCCAGG	LHX4	ENSG00000121454	0.482236667678667	[]	[]	4	hSpCas9	negative selection	2686634
180230577	180230600	1	-	27260157	HT1080	viability	TCGGCACACCTAGCATCTCCGGG	LHX4	ENSG00000121454	-0.323449356066989	[]	[]	-7	hSpCas9	negative selection	2690420
180248325	180248348	1	+	27260157	HT1080	viability	CAAGTTCATCCTGAAGGTCCTGG	LHX4	ENSG00000121454	0.021841805574058	[]	[]	0	hSpCas9	negative selection	2693589
180248366	180248389	1	-	27260157	HT1080	viability	GCAGTCTGCACACTTGAGGCAGG	LHX4	ENSG00000121454	0.426121042918078	[]	[]	4	hSpCas9	negative selection	2717251
180248336	180248359	1	+	27260157	HT1080	viability	TGAAGGTCCTGGACAGACACTGG	LHX4	ENSG00000121454	0.438058542423794	[]	[]	4	hSpCas9	negative selection	2718253
180248310	180248333	1	-	27260157	HT1080	viability	TGAACTTGTCCAGGATGTGCTGG	LHX4	ENSG00000121454	-0.913072311434251	[]	[]	-8	hSpCas9	negative selection	2725713
180248319	180248342	1	+	27260157	MKN45	viability	CCTGGACAAGTTCATCCTGAAGG	LHX4	ENSG00000121454	1.14442491528903	[]	[]	8	hSpCas9	negative selection	2726028
180248379	180248402	1	+	27260157	MKN45	viability	TGCAGACTGCCAGATGCAGCTGG	LHX4	ENSG00000121454	0.0454734004750216	[]	[]	0	hSpCas9	negative selection	2726170
180248388	180248411	1	-	27260157	MKN45	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	1.4782766952979	[]	[]	9	hSpCas9	negative selection	2728374
180266449	180266472	1	-	27260157	MKN45	viability	AGACAAAGTCCTGGGCCTTGCGG	LHX4	ENSG00000121454	-0.5614549542597	[]	[]	-6	hSpCas9	negative selection	2728481
180230525	180230548	1	-	27260157	MKN45	viability	AGTCGCACTCTGCATCATCTCGG	LHX4	ENSG00000121454	-0.998672229705393	[]	[]	-8	hSpCas9	negative selection	2730723
180248291	180248314	1	-	27260157	MKN45	viability	CTGGTTGCAGCCAGCGCACTGGG	LHX4	ENSG00000121454	-0.866413791133079	[]	[]	-7	hSpCas9	negative selection	2734650
180248290	180248313	1	-	27260157	MKN45	viability	TGGTTGCAGCCAGCGCACTGGGG	LHX4	ENSG00000121454	-0.506966116741396	[]	[]	-6	hSpCas9	negative selection	2736292
180248334	180248357	1	-	27260157	MKN45	viability	AGTGTCTGTCCAGGACCTTCAGG	LHX4	ENSG00000121454	-0.159643688058303	[]	[]	0	hSpCas9	negative selection	2737373
180266405	180266428	1	+	27260157	MKN45	viability	AAATGCACGGCCTGCCAGCAGGG	LHX4	ENSG00000121454	0.933136476693416	[]	[]	8	hSpCas9	negative selection	2739490
180248301	180248324	1	+	27260157	MKN45	viability	TGGCTGCAACCAGCACATCCTGG	LHX4	ENSG00000121454	-0.285227953752704	[]	[]	-1	hSpCas9	negative selection	2757327
180248343	180248366	1	-	27260157	MKN45	viability	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.733268993855731	[]	[]	-7	hSpCas9	negative selection	2760046
180248399	180248422	1	+	27260157	MKN45	viability	TGGCGGACAGGTGCTTCTCCAGG	LHX4	ENSG00000121454	-0.220873051895011	[]	[]	-1	hSpCas9	negative selection	2762764
180230577	180230600	1	-	27260157	MKN45	viability	TCGGCACACCTAGCATCTCCGGG	LHX4	ENSG00000121454	-1.36499795535333	[]	[]	-8	hSpCas9	negative selection	2766550
180248325	180248348	1	+	27260157	MKN45	viability	CAAGTTCATCCTGAAGGTCCTGG	LHX4	ENSG00000121454	0.110094465181546	[]	[]	4	hSpCas9	negative selection	2769719
180248366	180248389	1	-	27260157	MKN45	viability	GCAGTCTGCACACTTGAGGCAGG	LHX4	ENSG00000121454	-0.0575182213057364	[]	[]	0	hSpCas9	negative selection	2793381
180248336	180248359	1	+	27260157	MKN45	viability	TGAAGGTCCTGGACAGACACTGG	LHX4	ENSG00000121454	0.117332675964584	[]	[]	4	hSpCas9	negative selection	2794383
180248310	180248333	1	-	27260157	MKN45	viability	TGAACTTGTCCAGGATGTGCTGG	LHX4	ENSG00000121454	-0.962862318957618	[]	[]	-7	hSpCas9	negative selection	2801843
180248319	180248342	1	+	27260157	RKO	viability	CCTGGACAAGTTCATCCTGAAGG	LHX4	ENSG00000121454	1.02854650104191	[]	[]	9	hSpCas9	negative selection	2802158
180248379	180248402	1	+	27260157	RKO	viability	TGCAGACTGCCAGATGCAGCTGG	LHX4	ENSG00000121454	-0.162776552628776	[]	[]	-1	hSpCas9	negative selection	2802300
180248388	180248411	1	-	27260157	RKO	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.95671727413883	[]	[]	8	hSpCas9	negative selection	2804504
180266449	180266472	1	-	27260157	RKO	viability	AGACAAAGTCCTGGGCCTTGCGG	LHX4	ENSG00000121454	0.423391640275263	[]	[]	2	hSpCas9	negative selection	2804611
180230525	180230548	1	-	27260157	RKO	viability	AGTCGCACTCTGCATCATCTCGG	LHX4	ENSG00000121454	0.515197154054283	[]	[]	2	hSpCas9	negative selection	2806853
180248291	180248314	1	-	27260157	RKO	viability	CTGGTTGCAGCCAGCGCACTGGG	LHX4	ENSG00000121454	-0.521167626899239	[]	[]	-6	hSpCas9	negative selection	2810780
180248290	180248313	1	-	27260157	RKO	viability	TGGTTGCAGCCAGCGCACTGGGG	LHX4	ENSG00000121454	-0.525437647293871	[]	[]	-6	hSpCas9	negative selection	2812422
180248334	180248357	1	-	27260157	RKO	viability	AGTGTCTGTCCAGGACCTTCAGG	LHX4	ENSG00000121454	0.0784924768069273	[]	[]	0	hSpCas9	negative selection	2813503
180266405	180266428	1	+	27260157	RKO	viability	AAATGCACGGCCTGCCAGCAGGG	LHX4	ENSG00000121454	1.01339977955661	[]	[]	9	hSpCas9	negative selection	2815620
180248301	180248324	1	+	27260157	RKO	viability	TGGCTGCAACCAGCACATCCTGG	LHX4	ENSG00000121454	0.0126356249541604	[]	[]	0	hSpCas9	negative selection	2833457
180248343	180248366	1	-	27260157	RKO	viability	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	0.527113433332319	[]	[]	3	hSpCas9	negative selection	2836176
180248399	180248422	1	+	27260157	RKO	viability	TGGCGGACAGGTGCTTCTCCAGG	LHX4	ENSG00000121454	-0.434160327064865	[]	[]	-6	hSpCas9	negative selection	2838894
180230577	180230600	1	-	27260157	RKO	viability	TCGGCACACCTAGCATCTCCGGG	LHX4	ENSG00000121454	-0.412696880355489	[]	[]	-6	hSpCas9	negative selection	2842680
180248325	180248348	1	+	27260157	RKO	viability	CAAGTTCATCCTGAAGGTCCTGG	LHX4	ENSG00000121454	0.809923881866747	[]	[]	8	hSpCas9	negative selection	2845849
180248366	180248389	1	-	27260157	RKO	viability	GCAGTCTGCACACTTGAGGCAGG	LHX4	ENSG00000121454	0.270414136149301	[]	[]	1	hSpCas9	negative selection	2869511
180248336	180248359	1	+	27260157	RKO	viability	TGAAGGTCCTGGACAGACACTGG	LHX4	ENSG00000121454	0.752114063624404	[]	[]	8	hSpCas9	negative selection	2870513
180248310	180248333	1	-	27260157	RKO	viability	TGAACTTGTCCAGGATGTGCTGG	LHX4	ENSG00000121454	-0.386706898359965	[]	[]	-6	hSpCas9	negative selection	2877973
180248319	180248342	1	+	27260157	SF268	viability	CCTGGACAAGTTCATCCTGAAGG	LHX4	ENSG00000121454	1.5206241329239	[]	[]	9	hSpCas9	negative selection	2878288
180248379	180248402	1	+	27260157	SF268	viability	TGCAGACTGCCAGATGCAGCTGG	LHX4	ENSG00000121454	0.995431001146858	[]	[]	9	hSpCas9	negative selection	2878430
180248388	180248411	1	-	27260157	SF268	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.728337504302103	[]	[]	8	hSpCas9	negative selection	2880634
180266449	180266472	1	-	27260157	SF268	viability	AGACAAAGTCCTGGGCCTTGCGG	LHX4	ENSG00000121454	0.545922692977656	[]	[]	8	hSpCas9	negative selection	2880741
180230525	180230548	1	-	27260157	SF268	viability	AGTCGCACTCTGCATCATCTCGG	LHX4	ENSG00000121454	-0.100572661058233	[]	[]	-1	hSpCas9	negative selection	2882983
180248291	180248314	1	-	27260157	SF268	viability	CTGGTTGCAGCCAGCGCACTGGG	LHX4	ENSG00000121454	0.26676338885136	[]	[]	4	hSpCas9	negative selection	2886910
180248290	180248313	1	-	27260157	SF268	viability	TGGTTGCAGCCAGCGCACTGGGG	LHX4	ENSG00000121454	-0.318804673152728	[]	[]	-2	hSpCas9	negative selection	2888552
180248334	180248357	1	-	27260157	SF268	viability	AGTGTCTGTCCAGGACCTTCAGG	LHX4	ENSG00000121454	-0.246452225623538	[]	[]	-2	hSpCas9	negative selection	2889633
180266405	180266428	1	+	27260157	SF268	viability	AAATGCACGGCCTGCCAGCAGGG	LHX4	ENSG00000121454	0.782097913604024	[]	[]	8	hSpCas9	negative selection	2891750
180248301	180248324	1	+	27260157	SF268	viability	TGGCTGCAACCAGCACATCCTGG	LHX4	ENSG00000121454	0.818202217017673	[]	[]	8	hSpCas9	negative selection	2909587
180248343	180248366	1	-	27260157	SF268	viability	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.676122019188657	[]	[]	-5	hSpCas9	negative selection	2912306
180248399	180248422	1	+	27260157	SF268	viability	TGGCGGACAGGTGCTTCTCCAGG	LHX4	ENSG00000121454	0.0230954550673531	[]	[]	0	hSpCas9	negative selection	2915024
180230577	180230600	1	-	27260157	SF268	viability	TCGGCACACCTAGCATCTCCGGG	LHX4	ENSG00000121454	-0.562524361797008	[]	[]	-4	hSpCas9	negative selection	2918810
180248325	180248348	1	+	27260157	SF268	viability	CAAGTTCATCCTGAAGGTCCTGG	LHX4	ENSG00000121454	0.786150222953418	[]	[]	8	hSpCas9	negative selection	2921979
180248366	180248389	1	-	27260157	SF268	viability	GCAGTCTGCACACTTGAGGCAGG	LHX4	ENSG00000121454	-0.668203372752169	[]	[]	-5	hSpCas9	negative selection	2945641
180248336	180248359	1	+	27260157	SF268	viability	TGAAGGTCCTGGACAGACACTGG	LHX4	ENSG00000121454	0.995890590625606	[]	[]	9	hSpCas9	negative selection	2946643
180248310	180248333	1	-	27260157	SF268	viability	TGAACTTGTCCAGGATGTGCTGG	LHX4	ENSG00000121454	0.0296343236541305	[]	[]	0	hSpCas9	negative selection	2954103
180230550	180230573	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTTGACAGCCCCTTCCGCGGGG	LHX4	ENSG00000121454	-0.16957504984216193	[3,3]	[3,2]	-2	hSpCas9	positive selection	2999397
180266503	180266526	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAACCGGCAGCTGGCCACGGGG	LHX4	ENSG00000121454	0.5417213691832039	[3,3]	[4,4]	9	hSpCas9	positive selection	2999398
180230536	180230559	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.16035005531299634	[2,2]	[3,0]	-2	hSpCas9	positive selection	2999399
180266533	180266556	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TCTACCTCATGGAGGACGGGCGG	LHX4	ENSG00000121454	-0.3581699077545034	[3,2]	[2,0]	-5	hSpCas9	positive selection	2999400
180230550	180230573	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTTGACAGCCCCTTCCGCGGGG	LHX4	ENSG00000121454	-0.3208023217665198	[3,3]	[2,1]	-5	hSpCas9	positive selection	3067255
180266503	180266526	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAACCGGCAGCTGGCCACGGGG	LHX4	ENSG00000121454	-0.31895586403883874	[3,3]	[3,0]	-5	hSpCas9	positive selection	3067256
180230536	180230559	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.31296710260091676	[2,2]	[2,1]	5	hSpCas9	positive selection	3067257
180266533	180266556	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TCTACCTCATGGAGGACGGGCGG	LHX4	ENSG00000121454	-0.5885270076756964	[3,3]	[2,0]	-7	hSpCas9	positive selection	3067258
180248388	180248411		-	24336571	A375	resistance to PLX after 7 days	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.20424940440754646	[21,21]	[19,17]	-6	hSpCas9	positive selection	3124613
180248343	180248366		-	24336571	A375	resistance to PLX after 7 days	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.4467408186612287	[21,16]	[13,13]	-9	hSpCas9	positive selection	3124614
180230578	180230601		-	24336571	A375	resistance to PLX after 7 days	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.06235552988762605	[18,23]	[23,20]	2	hSpCas9	positive selection	3124615
180248388	180248411		-	24336571	A375	resistance to PLX after 14 days	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.6863709587855276	[16,21]	[5,3]	-7	hSpCas9	positive selection	3182406
180248343	180248366		-	24336571	A375	resistance to PLX after 14 days	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.9735613668793364	[14,12]	[2,2]	-9	hSpCas9	positive selection	3182407
180230578	180230601		-	24336571	A375	resistance to PLX after 14 days	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.06673160709170567	[19,23]	[8,8]	0	hSpCas9	positive selection	3182408
180248388	180248411		-	24336571	A375	viability after 7 days	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.03848370051931804	[22]	[21,21]	0	hSpCas9	negative selection	3240199
180248343	180248366		-	24336571	A375	viability after 7 days	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.03466771332457197	[20]	[21,16]	0	hSpCas9	negative selection	3240200
180230578	180230601		-	24336571	A375	viability after 7 days	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.3706848364003787	[16]	[18,23]	5	hSpCas9	negative selection	3240201
180248388	180248411		-	24336571	A375	viability after 14 days	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.10417402777599993	[22]	[16,21]	-1	hSpCas9	negative selection	3297992
180248343	180248366		-	24336571	A375	viability after 14 days	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.47508027763183863	[20]	[14,12]	-5	hSpCas9	negative selection	3297993
180230578	180230601		-	24336571	A375	viability after 14 days	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.4011830429325363	[16]	[19,23]	5	hSpCas9	negative selection	3297994
180266583	180266606	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	-0.7979562240553546	[265,265]	[0,0]	-5	hSpCas9	positive selection	3377126
180230535	180230558	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.9174762085612103	[80,80]	[0,0]	4	hSpCas9	positive selection	3377127
180248292	180248315	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	1.0478728458168853	[73,73]	[0,0]	5	hSpCas9	positive selection	3377128
180230550	180230573	1	-	26780180	HT29	viability (Avana library 4 designs)	CCTTGACAGCCCCTTCCGCGGGG	LHX4	ENSG00000121454	-0.118820474371622	[]	[]	-2	hSpCas9	negative selection	3436944
180266502	180266525	1	+	26780180	HT29	viability (Avana library 4 designs)	GCAACCGGCAGCTGGCCACGGGG	LHX4	ENSG00000121454	1.13429651836458	[]	[]	4	hSpCas9	negative selection	3436945
180230535	180230558	1	+	26780180	HT29	viability (Avana library 4 designs)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	1.07045315189346	[]	[]	4	hSpCas9	negative selection	3436946
180266532	180266555	1	+	26780180	HT29	viability (Avana library 4 designs)	TCTACCTCATGGAGGACGGGCGG	LHX4	ENSG00000121454	2.12903701437088	[]	[]	7	hSpCas9	negative selection	3436947
180230535	180230558	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	3.28646115202528	[]	[]	5	hSpCas9	negative selection	3525415
180230550	180230573	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTTGACAGCCCCTTCCGCGGGG	LHX4	ENSG00000121454	-0.661887462655081	[]	[]	-1	hSpCas9	negative selection	3525416
180266532	180266555	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTACCTCATGGAGGACGGGCGG	LHX4	ENSG00000121454	3.44427804605569	[]	[]	5	hSpCas9	negative selection	3525417
180266502	180266525	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAACCGGCAGCTGGCCACGGGG	LHX4	ENSG00000121454	2.48200386388338	[]	[]	3	hSpCas9	negative selection	3525418
180266536	180266559	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCAGCCGCCCGTCCTCCATGAGG	LHX4	ENSG00000121454	2.0627446969664	[]	[]	3	hSpCas9	negative selection	3525419
180248382	180248405	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.695971663037823	[]	[]	1	hSpCas9	negative selection	3525420
180230535	180230558	1	+	26780180	A375	viability (Avana lentiGuide)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	5.67858004687763	[]	[]	5	hSpCas9	negative selection	3634074
180230550	180230573	1	-	26780180	A375	viability (Avana lentiGuide)	CCTTGACAGCCCCTTCCGCGGGG	LHX4	ENSG00000121454	4.49609391635065	[]	[]	4	hSpCas9	negative selection	3634075
180266532	180266555	1	+	26780180	A375	viability (Avana lentiGuide)	TCTACCTCATGGAGGACGGGCGG	LHX4	ENSG00000121454	26.140969423253	[]	[]	9	hSpCas9	negative selection	3634076
180266502	180266525	1	+	26780180	A375	viability (Avana lentiGuide)	GCAACCGGCAGCTGGCCACGGGG	LHX4	ENSG00000121454	7.09590952824311	[]	[]	5	hSpCas9	negative selection	3634077
180266536	180266559	1	-	26780180	A375	viability (Avana lentiGuide)	CCAGCCGCCCGTCCTCCATGAGG	LHX4	ENSG00000121454	-0.483753447543119	[]	[]	0	hSpCas9	negative selection	3634078
180248382	180248405	1	+	26780180	A375	viability (Avana lentiGuide)	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	-0.279055005559911	[]	[]	0	hSpCas9	negative selection	3634079
180230535	180230558	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.1868502570961213	[4]	[5,4]	5	hSpCas9	positive selection	3742733
180230550	180230573	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTTGACAGCCCCTTCCGCGGGG	LHX4	ENSG00000121454	-0.23662500939805928	[4]	[4,2]	-4	hSpCas9	positive selection	3742734
180266532	180266555	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTACCTCATGGAGGACGGGCGG	LHX4	ENSG00000121454	-0.07695817128962504	[4]	[4,3]	-1	hSpCas9	positive selection	3742735
180266502	180266525	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAACCGGCAGCTGGCCACGGGG	LHX4	ENSG00000121454	-0.32445580171337174	[4]	[5,1]	-5	hSpCas9	positive selection	3742736
180266536	180266559	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCAGCCGCCCGTCCTCCATGAGG	LHX4	ENSG00000121454	0.20741618319867855	[5]	[6,5]	6	hSpCas9	positive selection	3742737
180248382	180248405	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.1380698925770204	[4]	[5,4]	3	hSpCas9	positive selection	3742738
180230535	180230558	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.8545681081897205	[4]	[0,2]	-8	hSpCas9	positive selection	3851340
180230550	180230573	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTTGACAGCCCCTTCCGCGGGG	LHX4	ENSG00000121454	-0.6723968398962558	[5]	[2,2]	-7	hSpCas9	positive selection	3851341
180266532	180266555	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTACCTCATGGAGGACGGGCGG	LHX4	ENSG00000121454	-0.6285306606990937	[4]	[0,4]	-7	hSpCas9	positive selection	3851342
180266502	180266525	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAACCGGCAGCTGGCCACGGGG	LHX4	ENSG00000121454	-0.20583781128901074	[5]	[3,3]	-3	hSpCas9	positive selection	3851343
180266536	180266559	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCAGCCGCCCGTCCTCCATGAGG	LHX4	ENSG00000121454	0.127554402552189	[6]	[5,6]	3	hSpCas9	positive selection	3851344
180248382	180248405	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	-0.5588028330059298	[4]	[4,0]	-6	hSpCas9	positive selection	3851345
180248388	180248411	1	-	26780180	A375	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.926727361832434	[]	[]	4	hSpCas9	negative selection	3957006
180230578	180230601	1	-	26780180	A375	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	1.10578240643828	[]	[]	5	hSpCas9	negative selection	3957007
180266583	180266606	1	-	26780180	A375	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.743513214529105	[]	[]	2	hSpCas9	negative selection	3957008
180230535	180230558	1	+	26780180	A375	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	1.0083962383547	[]	[]	5	hSpCas9	negative selection	3957009
180266392	180266415	1	+	26780180	A375	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	1.37233428705233	[]	[]	7	hSpCas9	negative selection	3957010
180248292	180248315	1	-	26780180	A375	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	1.66794780547782	[]	[]	9	hSpCas9	negative selection	3957011
180248388	180248411	1	-	26780180	HT29	viability (GeCKOv2 library)	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.405181638428647	[]	[]	1	hSpCas9	negative selection	4064972
180230578	180230601	1	-	26780180	HT29	viability (GeCKOv2 library)	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	1.73957792773066	[]	[]	8	hSpCas9	negative selection	4064973
180266583	180266606	1	-	26780180	HT29	viability (GeCKOv2 library)	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.19721823636082	[]	[]	0	hSpCas9	negative selection	4064974
180230535	180230558	1	+	26780180	HT29	viability (GeCKOv2 library)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	1.84299815059362	[]	[]	8	hSpCas9	negative selection	4064975
180266392	180266415	1	+	26780180	HT29	viability (GeCKOv2 library)	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.986449706350224	[]	[]	4	hSpCas9	negative selection	4064976
180248292	180248315	1	-	26780180	HT29	viability (GeCKOv2 library)	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	1.35926895701205	[]	[]	7	hSpCas9	negative selection	4064977
180248388	180248411	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.1868019381455711	[4]	[2,2]	-4	hSpCas9	positive selection	4148679
180248343	180248366	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.31338548113357195	[4]	[2,1]	-6	hSpCas9	positive selection	4148680
180230578	180230601	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.04237416857278463	[4]	[1,3]	-1	hSpCas9	positive selection	4148681
180248388	180248411	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.7840735556916749	[4]	[2,4,3,3]	5	hSpCas9	positive selection	4212701
180248343	180248366	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTGTGCCAGTGTCTGTCCAGG	LHX4	ENSG00000121454	-0.020813847178445317	[3]	[0,3,2,0]	0	hSpCas9	positive selection	4212702
180230578	180230601	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	1.0850332368611935	[4]	[3,0,4,4]	7	hSpCas9	positive selection	4212703
180266392	180266415	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.1183152787686424	[2]	[1,1]	-2	hSpCas9	positive selection	4280126
180248388	180248411	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.18093917807988058	[2]	[2,0]	-4	hSpCas9	positive selection	4280127
180230578	180230601	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.13019078005073859	[2]	[1,1]	-3	hSpCas9	positive selection	4280128
180266583	180266606	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.3876408012036727	[3]	[2,3]	7	hSpCas9	positive selection	4344382
180230535	180230558	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.8956798275907776	[1]	[0,0]	-9	hSpCas9	positive selection	4344383
180248292	180248315	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.1136525833832378	[2]	[1,1]	-2	hSpCas9	positive selection	4344384
180248417	180248439	1	-	27760321	OCIAML3	viability	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	0.3819465277149412	[1068,863]	[815,1192]	4	hSpCas9	negative selection	4414386
180266393	180266415	1	+	27760321	OCIAML3	viability	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.5449884057156196	[394,304]	[336,473]	6	hSpCas9	negative selection	4414387
180266529	180266551	1	+	27760321	OCIAML3	viability	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.43871884008810147	[244,183]	[165,302]	5	hSpCas9	negative selection	4414388
180248417	180248439	1	-	27760321	OCIAML2	viability	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.44296287520084543	[1068,863]	[524,633]	-5	hSpCas9	negative selection	4497849
180266393	180266415	1	+	27760321	OCIAML2	viability	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.570092707069028	[394,304]	[311,555]	7	hSpCas9	negative selection	4497850
180266529	180266551	1	+	27760321	OCIAML2	viability	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.628545632179552	[244,183]	[221,323]	8	hSpCas9	negative selection	4497851
180248417	180248439	1	-	27760321	MV411	viability	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.5514283752152319	[1068,863]	[234,729]	-4	hSpCas9	negative selection	4581312
180266393	180266415	1	+	27760321	MV411	viability	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	1.269368193163446	[394,304]	[441,718]	8	hSpCas9	negative selection	4581313
180266529	180266551	1	+	27760321	MV411	viability	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	1.5627707647268951	[244,183]	[0,1035]	9	hSpCas9	negative selection	4581314
180248417	180248439	1	-	27760321	HL60	viability	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	0.3380368519342254	[1068,863]	[861,1130]	4	hSpCas9	negative selection	4664775
180266393	180266415	1	+	27760321	HL60	viability	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.2915675363236443	[394,304]	[343,350]	3	hSpCas9	negative selection	4664776
180266529	180266551	1	+	27760321	HL60	viability	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.4279946987506257	[244,183]	[175,294]	5	hSpCas9	negative selection	4664777
180248417	180248439	1	-	27760321	HT1080	viability	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-1.9480271430923848	[863,673]	[34,127]	-6	hSpCas9	negative selection	4748238
180266393	180266415	1	+	27760321	HT1080	viability	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.1797312222736306	[304,237]	[31,164]	-1	hSpCas9	negative selection	4748239
180266529	180266551	1	+	27760321	HT1080	viability	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	1.5491584395367717	[183,143]	[195,185]	8	hSpCas9	negative selection	4748240
180248417	180248439	1	-	27760321	HT29	viability after 7 days	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	0.374411810951617	[863,673]	[1573,1195,1119]	6	hSpCas9	negative selection	4831701
180266393	180266415	1	+	27760321	HT29	viability after 7 days	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.08613626039144473	[304,237]	[361,243,382]	-1	hSpCas9	negative selection	4831702
180266529	180266551	1	+	27760321	HT29	viability after 7 days	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	-0.45120953841012335	[183,143]	[158,174,129]	-6	hSpCas9	negative selection	4831703
180248417	180248439	1	-	27760321	HT29	viability after 25 days	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.5567053741970306	[863,673]	[475,562,778]	-5	hSpCas9	negative selection	4915164
180266393	180266415	1	+	27760321	HT29	viability after 25 days	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.20736267047866136	[304,237]	[374,357,337]	2	hSpCas9	negative selection	4915165
180266529	180266551	1	+	27760321	HT29	viability after 25 days	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.3992550113183708	[183,143]	[210,160,385]	4	hSpCas9	negative selection	4915166
180248417	180248439	1	-	27760321	HT29	viability after 22 days	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.39396318059750113	[863,673]	[753,649,622]	-4	hSpCas9	negative selection	4998627
180266393	180266415	1	+	27760321	HT29	viability after 22 days	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.44567095946405566	[304,237]	[415,406,459]	5	hSpCas9	negative selection	4998628
180266529	180266551	1	+	27760321	HT29	viability after 22 days	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.06739417251032753	[183,143]	[122,183,291]	0	hSpCas9	negative selection	4998629
180248417	180248439	1	-	27760321	HT29	viability after 19 days	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.16351021637099206	[863,673]	[963,815,600]	-1	hSpCas9	negative selection	5082090
180266393	180266415	1	+	27760321	HT29	viability after 19 days	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.3263818926417528	[304,237]	[513,470,202]	3	hSpCas9	negative selection	5082091
180266529	180266551	1	+	27760321	HT29	viability after 19 days	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.3355916469726755	[183,143]	[216,201,286]	3	hSpCas9	negative selection	5082092
180248417	180248439	1	-	27760321	HT29	viability after 16 days	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.3668880792465704	[863,673]	[751,565,693]	-4	hSpCas9	negative selection	5165553
180266393	180266415	1	+	27760321	HT29	viability after 16 days	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.4457978275669923	[304,237]	[416,506,314]	5	hSpCas9	negative selection	5165554
180266529	180266551	1	+	27760321	HT29	viability after 16 days	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.08022920755112084	[183,143]	[155,132,290]	0	hSpCas9	negative selection	5165555
180248417	180248439	1	-	27760321	HT29	viability after 13 days	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.11167296539096305	[863,673]	[723,926,825]	-1	hSpCas9	negative selection	5249016
180266393	180266415	1	+	27760321	HT29	viability after 13 days	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.4532441758954421	[304,237]	[443,493,359]	6	hSpCas9	negative selection	5249017
180266529	180266551	1	+	27760321	HT29	viability after 13 days	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	-0.17634629064626206	[183,143]	[241,128,135]	-2	hSpCas9	negative selection	5249018
180248417	180248439	1	-	27760321	HT29	viability after 10 days	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	0.20212303464812797	[863,673]	[1055,1239,1022]	2	hSpCas9	negative selection	5332479
180266393	180266415	1	+	27760321	HT29	viability after 10 days	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.1828273664794311	[304,237]	[470,420,265]	2	hSpCas9	negative selection	5332480
180266529	180266551	1	+	27760321	HT29	viability after 10 days	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	0.24809643393700886	[183,143]	[96,355,278]	3	hSpCas9	negative selection	5332481
180248417	180248439	1	-	27760321	MOLM13	viability	CAGTAGACGCTCCCAGCCCTGG	LHX4	ENSG00000121454	-0.5951107862271369	[1068,863]	[277,427]	-4	hSpCas9	negative selection	5415942
180266393	180266415	1	+	27760321	MOLM13	viability	CGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	1.3690747450197507	[394,304]	[635,395]	8	hSpCas9	negative selection	5415943
180266529	180266551	1	+	27760321	MOLM13	viability	AATTCTACCTCATGGAGGACGG	LHX4	ENSG00000121454	-0.3713427737287882	[244,183]	[189,9]	-2	hSpCas9	negative selection	5415944
180230310	180230333	1	+	27661255	K562	viability	GAGAGCGAGATCAAAGGGACTGG	LHX4	ENSG00000121454	0.06325658290485096	[865,683]	[702,603]	2	dCas9-KRAB	negative selection	5490246
180230673	180230696	1	+	27661255	K562	viability	GCGGGCCGGACGCCGCTCAGGGG	LHX4	ENSG00000121454	0.09261033727546808	[400,447]	[443,289]	3	dCas9-KRAB	negative selection	5490247
180230715	180230738	1	+	27661255	K562	viability	GGGGCGCAGAGGCGGTCACAGGG	LHX4	ENSG00000121454	0.44754470625101506	[981,840]	[1026,968]	9	dCas9-KRAB	negative selection	5490248
180266392	180266415	1	+	27260156	BXPC3	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.09065378859661166	[222]	[201,235,251,180]	-2	hSpCas9	negative selection	5552586
180248388	180248411	1	-	27260156	BXPC3	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.20325644427471756	[361]	[383,406,446,519]	4	hSpCas9	negative selection	5552587
180230578	180230601	1	-	27260156	BXPC3	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.1061773574212328	[229]	[207,294,293,237]	2	hSpCas9	negative selection	5552588
180266583	180266606	1	-	27260156	BXPC3	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.13265852840845327	[605]	[629,594,810,760]	3	hSpCas9	negative selection	5616842
180230535	180230558	1	+	27260156	BXPC3	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.3275149873785608	[161]	[179,72,116,171]	-6	hSpCas9	negative selection	5616843
180248292	180248315	1	-	27260156	BXPC3	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.2922136133477773	[300]	[199,231,235,380]	-6	hSpCas9	negative selection	5616844
180266392	180266415	1	+	27260156	A673	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.30255814450424023	[222]	[347,256,442,271]	7	hSpCas9	negative selection	5673837
180248388	180248411	1	-	27260156	A673	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.07923356296924822	[361]	[630,426,451,339]	2	hSpCas9	negative selection	5673838
180230578	180230601	1	-	27260156	A673	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.035535569026553526	[229]	[196,325,250,294]	-1	hSpCas9	negative selection	5673839
180266583	180266606	1	-	27260156	A673	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.3273175266897004	[605]	[1069,916,846,829]	7	hSpCas9	negative selection	5738093
180230535	180230558	1	+	27260156	A673	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.2561643908044775	[161]	[183,149,83,240]	-6	hSpCas9	negative selection	5738094
180248292	180248315	1	-	27260156	A673	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.4258953499738365	[300]	[268,246,304,253]	-8	hSpCas9	negative selection	5738095
180266392	180266415	1	+	27260156	A375	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.017859883423449574	[222]	[272,423,187,198]	0	hSpCas9	negative selection	5795088
180248388	180248411	1	-	27260156	A375	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.2636810293120492	[361]	[314,436,324,342]	-4	hSpCas9	negative selection	5795089
180230578	180230601	1	-	27260156	A375	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.02544856395354156	[229]	[316,272,355,126]	0	hSpCas9	negative selection	5795090
180266583	180266606	1	-	27260156	A375	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.35835898777488384	[605]	[898,953,655,1099]	5	hSpCas9	negative selection	5859344
180230535	180230558	1	+	27260156	A375	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.6837127199969331	[161]	[106,151,177,46]	-7	hSpCas9	negative selection	5859345
180248292	180248315	1	-	27260156	A375	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.49868416639167035	[300]	[254,367,185,206]	-6	hSpCas9	negative selection	5859346
180266392	180266415	1	+	27260156	COLO741	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.0833492701297881	[222]	[309,312,283]	1	hSpCas9	negative selection	5916339
180248388	180248411	1	-	27260156	COLO741	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.13870951048928637	[361]	[470,446,350]	-3	hSpCas9	negative selection	5916340
180230578	180230601	1	-	27260156	COLO741	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.3337772657156699	[229]	[144,233,306]	-6	hSpCas9	negative selection	5916341
180266583	180266606	1	-	27260156	COLO741	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.2909912894707565	[605]	[1250,875,752]	6	hSpCas9	negative selection	5980595
180230535	180230558	1	+	27260156	COLO741	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.5229523390275204	[161]	[144,157,129]	-8	hSpCas9	negative selection	5980596
180248292	180248315	1	-	27260156	COLO741	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.395747730748891	[300]	[322,376,186]	-7	hSpCas9	negative selection	5980597
180266392	180266415	1	+	27260156	CAL120	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.08253104212789708	[222]	[239,348,194]	-1	hSpCas9	negative selection	6037590
180248388	180248411	1	-	27260156	CAL120	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.4376908875044248	[361]	[749,480,619]	6	hSpCas9	negative selection	6037591
180230578	180230601	1	-	27260156	CAL120	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.5842153671503005	[229]	[445,266,573]	8	hSpCas9	negative selection	6037592
180266583	180266606	1	-	27260156	CAL120	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.6561444917545824	[605]	[1556,983,1080]	8	hSpCas9	negative selection	6101846
180230535	180230558	1	+	27260156	CAL120	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.305971414496218	[161]	[127,144,209]	-4	hSpCas9	negative selection	6101847
180248292	180248315	1	-	27260156	CAL120	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.06343287396700925	[300]	[468,217,403]	-1	hSpCas9	negative selection	6101848
180266392	180266415	1	+	27260156	CADOES1	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.19585698402482754	[222]	[197,141,298,313]	3	hSpCas9	negative selection	6158841
180248388	180248411	1	-	27260156	CADOES1	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.07944885163179477	[361]	[235,292,291,458]	-1	hSpCas9	negative selection	6158842
180230578	180230601	1	-	27260156	CADOES1	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.19126400029957802	[229]	[216,215,164,149]	-3	hSpCas9	negative selection	6158843
180266583	180266606	1	-	27260156	CADOES1	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.3993694391230317	[605]	[852,619,805,691]	6	hSpCas9	negative selection	6223097
180230535	180230558	1	+	27260156	CADOES1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.4711095821656479	[161]	[96,40,178,117]	-7	hSpCas9	negative selection	6223098
180248292	180248315	1	-	27260156	CADOES1	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.1994755054447085	[300]	[235,231,216,291]	-3	hSpCas9	negative selection	6223099
180266392	180266415	1	+	27260156	EWS502	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.31691665343134	[222]	[178,399,274,333]	5	hSpCas9	negative selection	6280092
180248388	180248411	1	-	27260156	EWS502	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.14656231375483442	[361]	[359,536,402,396]	2	hSpCas9	negative selection	6280093
180230578	180230601	1	-	27260156	EWS502	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.19549964668178377	[229]	[177,177,300,198]	-3	hSpCas9	negative selection	6280094
180266583	180266606	1	-	27260156	EWS502	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.40486780584261384	[605]	[702,947,982,771]	7	hSpCas9	negative selection	6344348
180230535	180230558	1	+	27260156	EWS502	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.3065874791446086	[161]	[115,57,200,189]	-5	hSpCas9	negative selection	6344349
180248292	180248315	1	-	27260156	EWS502	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.416568165815171	[300]	[263,261,212,208]	-6	hSpCas9	negative selection	6344350
180266392	180266415	1	+	27260156	EW8	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.13759213409997162	[222]	[194,217,140,249]	2	hSpCas9	negative selection	6401343
180248388	180248411	1	-	27260156	EW8	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.2678277075295477	[361]	[419,278,273,458]	5	hSpCas9	negative selection	6401344
180230578	180230601	1	-	27260156	EW8	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.1835142974908791	[229]	[204,367,118,169]	3	hSpCas9	negative selection	6401345
180266583	180266606	1	-	27260156	EW8	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.36327085287877914	[605]	[625,643,574,688]	6	hSpCas9	negative selection	6465599
180230535	180230558	1	+	27260156	EW8	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.6403676287356661	[161]	[110,119,41,73]	-8	hSpCas9	negative selection	6465600
180248292	180248315	1	-	27260156	EW8	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.1447252354331371	[300]	[270,122,279,202]	-3	hSpCas9	negative selection	6465601
180266392	180266415	1	+	27260156	CORL105	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.6765821853531528	[222]	[431,427,558,272]	9	hSpCas9	negative selection	6522594
180248388	180248411	1	-	27260156	CORL105	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.09953628048761787	[361]	[446,372,559,453]	1	hSpCas9	negative selection	6522595
180230578	180230601	1	-	27260156	CORL105	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.3307975622481585	[229]	[195,236,293,140]	-6	hSpCas9	negative selection	6522596
180266583	180266606	1	-	27260156	CORL105	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.6626298468629483	[605]	[992,1010,1526,1021]	9	hSpCas9	negative selection	6586850
180230535	180230558	1	+	27260156	CORL105	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.036960510605783314	[161]	[78,136,290,245]	0	hSpCas9	negative selection	6586851
180248292	180248315	1	-	27260156	CORL105	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.22026742272282285	[300]	[240,367,330,270]	-4	hSpCas9	negative selection	6586852
180266392	180266415	1	+	27260156	HS294T	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	1.103698555137597	[222]	[105,95,425,110]	9	hSpCas9	negative selection	6643845
180248388	180248411	1	-	27260156	HS294T	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.6010586212975841	[361]	[152,204,246,256]	7	hSpCas9	negative selection	6643846
180230578	180230601	1	-	27260156	HS294T	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.4595391509478619	[229]	[50,45,65,103]	-6	hSpCas9	negative selection	6643847
180266583	180266606	1	-	27260156	HS294T	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.42751726914879706	[605]	[281,314,373,286]	6	hSpCas9	negative selection	6708101
180230535	180230558	1	+	27260156	HS294T	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-1.084301264897209	[161]	[26,35,30,22]	-9	hSpCas9	negative selection	6708102
180248292	180248315	1	-	27260156	HS294T	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	0.13072676344538947	[300]	[33,48,105,372]	1	hSpCas9	negative selection	6708103
180266392	180266415	1	+	27260156	HCC44	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.1586745965374997	[222]	[203,183,462,309]	2	hSpCas9	negative selection	6765096
180248388	180248411	1	-	27260156	HCC44	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.008182784177055036	[361]	[581,179,442,489]	0	hSpCas9	negative selection	6765097
180230578	180230601	1	-	27260156	HCC44	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.05048214625919656	[229]	[268,250,312,252]	0	hSpCas9	negative selection	6765098
180266583	180266606	1	-	27260156	HCC44	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.4827510904913248	[605]	[945,688,950,1262]	7	hSpCas9	negative selection	6829352
180230535	180230558	1	+	27260156	HCC44	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.7851094246833861	[161]	[141,63,54,161]	-8	hSpCas9	negative selection	6829353
180248292	180248315	1	-	27260156	HCC44	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.17283510971706884	[300]	[299,258,397,271]	-3	hSpCas9	negative selection	6829354
180266392	180266415	1	+	27260156	G402	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.743842487274214	[222]	[838,142,629,255]	8	hSpCas9	negative selection	6886347
180248388	180248411	1	-	27260156	G402	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.056077517966499235	[361]	[617,570,263,287]	0	hSpCas9	negative selection	6886348
180230578	180230601	1	-	27260156	G402	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.6276288829453176	[229]	[126,148,298,142]	-6	hSpCas9	negative selection	6886349
180266583	180266606	1	-	27260156	G402	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.5568605579113148	[605]	[1350,848,998,1167]	7	hSpCas9	negative selection	6950603
180230535	180230558	1	+	27260156	G402	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.26773002197272944	[161]	[190,410,27,49]	-3	hSpCas9	negative selection	6950604
180248292	180248315	1	-	27260156	G402	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.48176892660808646	[300]	[269,189,392,197]	-5	hSpCas9	negative selection	6950605
180266392	180266415	1	+	27260156	L33	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.2643897208431605	[222]	[254,108,185,254]	5	hSpCas9	negative selection	7007598
180248388	180248411	1	-	27260156	L33	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.6629809198065154	[361]	[603,224,396,507]	9	hSpCas9	negative selection	7007599
180230578	180230601	1	-	27260156	L33	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.17986587268157717	[229]	[301,51,147,145]	-4	hSpCas9	negative selection	7007600
180266583	180266606	1	-	27260156	L33	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.36146516349271685	[605]	[906,360,416,659]	7	hSpCas9	negative selection	7071854
180230535	180230558	1	+	27260156	L33	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.6582150030760006	[161]	[74,60,52,102]	-9	hSpCas9	negative selection	7071855
180248292	180248315	1	-	27260156	L33	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.5339023449844638	[300]	[195,96,128,193]	-8	hSpCas9	negative selection	7071856
180266392	180266415	1	+	27260156	K562	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.24675577720293562	[222]	[258,191,242,242]	3	hSpCas9	negative selection	7128849
180248388	180248411	1	-	27260156	K562	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.3881540638129557	[361]	[574,294,310,495]	5	hSpCas9	negative selection	7128850
180230578	180230601	1	-	27260156	K562	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.48199944278737783	[229]	[857,160,87,94]	6	hSpCas9	negative selection	7128851
180266583	180266606	1	-	27260156	K562	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.4819547364597063	[605]	[733,998,615,672]	6	hSpCas9	negative selection	7193105
180230535	180230558	1	+	27260156	K562	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-1.7271501273749639	[161]	[40,23,79,28]	-9	hSpCas9	negative selection	7193106
180248292	180248315	1	-	27260156	K562	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.42604662681935723	[300]	[97,319,217,160]	-5	hSpCas9	negative selection	7193107
180266392	180266415	1	+	27260156	HT29	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.08735661617565915	[222]	[294,256,228,357]	1	hSpCas9	negative selection	7250100
180248388	180248411	1	-	27260156	HT29	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.1880875689481196	[361]	[563,382,580,471]	3	hSpCas9	negative selection	7250101
180230578	180230601	1	-	27260156	HT29	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.016132287976376114	[229]	[245,329,332,205]	0	hSpCas9	negative selection	7250102
180266583	180266606	1	-	27260156	HT29	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.342210258659287	[605]	[1215,896,725,910]	6	hSpCas9	negative selection	7314356
180230535	180230558	1	+	27260156	HT29	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.7126783054566181	[161]	[155,98,143,85]	-8	hSpCas9	negative selection	7314357
180248292	180248315	1	-	27260156	HT29	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.4604436774707783	[300]	[269,247,253,285]	-7	hSpCas9	negative selection	7314358
180266392	180266415	1	+	27260156	MHHES1	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.03162897945335397	[222]	[223,189,368,197]	0	hSpCas9	negative selection	7371351
180248388	180248411	1	-	27260156	MHHES1	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.24674646370908668	[361]	[587,355,624,379]	4	hSpCas9	negative selection	7371352
180230578	180230601	1	-	27260156	MHHES1	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.08914868365236528	[229]	[252,416,339,131]	1	hSpCas9	negative selection	7371353
180266583	180266606	1	-	27260156	MHHES1	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.08588558793357648	[605]	[868,827,596,634]	1	hSpCas9	negative selection	7435607
180230535	180230558	1	+	27260156	MHHES1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.8439540365178733	[161]	[84,109,191,32]	-9	hSpCas9	negative selection	7435608
180248292	180248315	1	-	27260156	MHHES1	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.5286530526097446	[300]	[127,430,182,205]	-7	hSpCas9	negative selection	7435609
180266392	180266415	1	+	27260156	MEWO	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.41988225135805146	[222]	[332,218,295]	8	hSpCas9	negative selection	7492602
180248388	180248411	1	-	27260156	MEWO	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.2830830706992208	[361]	[383,360,485]	6	hSpCas9	negative selection	7492603
180230578	180230601	1	-	27260156	MEWO	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.42971420864602816	[229]	[209,149,128]	-7	hSpCas9	negative selection	7492604
180266583	180266606	1	-	27260156	MEWO	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.09290974768792332	[605]	[729,632,474]	2	hSpCas9	negative selection	7556858
180230535	180230558	1	+	27260156	MEWO	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.3049300632698284	[161]	[162,89,122]	-6	hSpCas9	negative selection	7556859
180248292	180248315	1	-	27260156	MEWO	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.3162533095650699	[300]	[279,203,204]	-6	hSpCas9	negative selection	7556860
180266392	180266415	1	+	27260156	LNCAPCLONEFGC	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.37319992419590187	[222]	[264,178,289,321]	6	hSpCas9	negative selection	7613853
180248388	180248411	1	-	27260156	LNCAPCLONEFGC	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.20167515782833373	[361]	[371,460,344,319]	3	hSpCas9	negative selection	7613854
180230578	180230601	1	-	27260156	LNCAPCLONEFGC	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.0628713175737674	[229]	[193,127,215,266]	-1	hSpCas9	negative selection	7613855
180266583	180266606	1	-	27260156	LNCAPCLONEFGC	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.6070495703610713	[605]	[892,777,743,917]	8	hSpCas9	negative selection	7678109
180230535	180230558	1	+	27260156	LNCAPCLONEFGC	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.35176857708398335	[161]	[152,108,90,102]	-5	hSpCas9	negative selection	7678110
180248292	180248315	1	-	27260156	LNCAPCLONEFGC	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.40782153569482826	[300]	[313,145,233,133]	-6	hSpCas9	negative selection	7678111
180266392	180266415	1	+	27260156	PANC0327	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-1.0668139217812387	[222]	[109,74,88,107]	-8	hSpCas9	negative selection	7735104
180248388	180248411	1	-	27260156	PANC0327	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.158171621356944	[361]	[375,290,219,557]	2	hSpCas9	negative selection	7735105
180230578	180230601	1	-	27260156	PANC0327	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.01847404267383257	[229]	[249,200,258,100]	0	hSpCas9	negative selection	7735106
180266583	180266606	1	-	27260156	PANC0327	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.47858572538358324	[605]	[560,554,541,1350]	7	hSpCas9	negative selection	7799360
180230535	180230558	1	+	27260156	PANC0327	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.8570546436818858	[161]	[75,82,68,88]	-8	hSpCas9	negative selection	7799361
180248292	180248315	1	-	27260156	PANC0327	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.6282495879456855	[300]	[150,166,240,131]	-7	hSpCas9	negative selection	7799362
180266392	180266415	1	+	27260156	NCIH2009	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.3301367186085602	[222]	[613,298,306]	4	hSpCas9	negative selection	7856355
180248388	180248411	1	-	27260156	NCIH2009	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.4032302202798266	[361]	[865,581,597]	5	hSpCas9	negative selection	7856356
180230578	180230601	1	-	27260156	NCIH2009	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.7792049144136008	[229]	[182,218,157]	-7	hSpCas9	negative selection	7856357
180266583	180266606	1	-	27260156	NCIH2009	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.5254774816513379	[605]	[1764,780,1223]	7	hSpCas9	negative selection	7920611
180230535	180230558	1	+	27260156	NCIH2009	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.6304966600608042	[161]	[84,160,179]	-7	hSpCas9	negative selection	7920612
180248292	180248315	1	-	27260156	NCIH2009	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.17000919376884338	[300]	[297,305,502]	-2	hSpCas9	negative selection	7920613
180266392	180266415	1	+	27260156	NCIH1373	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.392581543502288	[222]	[304,291,472,60]	4	hSpCas9	negative selection	7977606
180248388	180248411	1	-	27260156	NCIH1373	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.3485928605440515	[361]	[694,375,500,140]	3	hSpCas9	negative selection	7977607
180230578	180230601	1	-	27260156	NCIH1373	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.2884209031028968	[229]	[181,143,248,71]	-3	hSpCas9	negative selection	7977608
180266583	180266606	1	-	27260156	NCIH1373	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.6039045300571574	[605]	[857,807,914,413]	6	hSpCas9	negative selection	8041862
180230535	180230558	1	+	27260156	NCIH1373	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-1.7686566511307684	[161]	[86,17,101,2]	-9	hSpCas9	negative selection	8041863
180248292	180248315	1	-	27260156	NCIH1373	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.7324501302983326	[300]	[100,192,196,81]	-6	hSpCas9	negative selection	8041864
180266392	180266415	1	+	27260156	PATU8902	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.47744212624878557	[222]	[235,303,177,178]	-5	hSpCas9	negative selection	8098857
180248388	180248411	1	-	27260156	PATU8902	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.13088298845708218	[361]	[541,515,800,242]	1	hSpCas9	negative selection	8098858
180230578	180230601	1	-	27260156	PATU8902	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.47503440998762403	[229]	[319,172,171,273]	-5	hSpCas9	negative selection	8098859
180266583	180266606	1	-	27260156	PATU8902	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.2428280833089178	[605]	[1079,1153,640,1231]	2	hSpCas9	negative selection	8163113
180230535	180230558	1	+	27260156	PATU8902	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.02949971163260856	[161]	[280,117,194,303]	0	hSpCas9	negative selection	8163114
180248292	180248315	1	-	27260156	PATU8902	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.5988393018541946	[300]	[164,362,174,450]	-5	hSpCas9	negative selection	8163115
180266392	180266415	1	+	27260156	PANC1	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.06356605498966839	[222]	[207,245,145,147]	-1	hSpCas9	negative selection	8220108
180248388	180248411	1	-	27260156	PANC1	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.317694483417558	[361]	[457,526,268,325]	5	hSpCas9	negative selection	8220109
180230578	180230601	1	-	27260156	PANC1	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.07216077908833363	[229]	[101,270,248,151]	-1	hSpCas9	negative selection	8220110
180266583	180266606	1	-	27260156	PANC1	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.3278705360739351	[605]	[492,1086,682,463]	5	hSpCas9	negative selection	8284364
180230535	180230558	1	+	27260156	PANC1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-1.105029759738514	[161]	[48,57,26,113]	-8	hSpCas9	negative selection	8284365
180248292	180248315	1	-	27260156	PANC1	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.8585013455863879	[300]	[114,184,205,81]	-8	hSpCas9	negative selection	8284366
180266392	180266415	1	+	27260156	PANC0813	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.5984180306579134	[222]	[299,347,369,549]	8	hSpCas9	negative selection	8341359
180248388	180248411	1	-	27260156	PANC0813	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.7006707592550265	[361]	[722,653,779,613]	9	hSpCas9	negative selection	8341360
180230578	180230601	1	-	27260156	PANC0813	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.659046599377269	[229]	[145,266,193,79]	-7	hSpCas9	negative selection	8341361
180266583	180266606	1	-	27260156	PANC0813	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.28066092012377586	[605]	[904,799,972,787]	4	hSpCas9	negative selection	8405615
180230535	180230558	1	+	27260156	PANC0813	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.04283605725223172	[161]	[216,150,143,226]	0	hSpCas9	negative selection	8405616
180248292	180248315	1	-	27260156	PANC0813	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.3810627052269895	[300]	[286,310,239,249]	-5	hSpCas9	negative selection	8405617
180266392	180266415	1	+	27260156	RDES	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.32272032210973056	[222]	[269,319,257,453]	5	hSpCas9	negative selection	8462610
180248388	180248411	1	-	27260156	RDES	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.07569033017078414	[361]	[368,487,252,456]	-1	hSpCas9	negative selection	8462611
180230578	180230601	1	-	27260156	RDES	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.5188063789539707	[229]	[164,182,179,212]	-7	hSpCas9	negative selection	8462612
180266583	180266606	1	-	27260156	RDES	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.3513496334449626	[605]	[860,933,763,976]	5	hSpCas9	negative selection	8526866
180230535	180230558	1	+	27260156	RDES	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.6318466755877141	[161]	[55,115,163,164]	-8	hSpCas9	negative selection	8526867
180248292	180248315	1	-	27260156	RDES	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.15327118920106786	[300]	[295,181,387,401]	-3	hSpCas9	negative selection	8526868
180266392	180266415	1	+	27260156	PC3	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.5168944632932774	[222]	[191,317,441,396]	9	hSpCas9	negative selection	8583861
180248388	180248411	1	-	27260156	PC3	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.0022658350686740047	[361]	[247,376,598,317]	0	hSpCas9	negative selection	8583862
180230578	180230601	1	-	27260156	PC3	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.014691744017344854	[229]	[111,211,528,224]	0	hSpCas9	negative selection	8583863
180266583	180266606	1	-	27260156	PC3	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.33853487280190253	[605]	[435,766,1202,900]	7	hSpCas9	negative selection	8648117
180230535	180230558	1	+	27260156	PC3	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.14194150213315226	[161]	[87,239,111,136]	-3	hSpCas9	negative selection	8648118
180248292	180248315	1	-	27260156	PC3	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.4474969267239617	[300]	[196,173,149,318]	-8	hSpCas9	negative selection	8648119
180266392	180266415	1	+	27260156	PATU8988T	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.053886807115134605	[222]	[340,114,163,268]	0	hSpCas9	negative selection	8705112
180248388	180248411	1	-	27260156	PATU8988T	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.11590003454548298	[361]	[480,448,254,335]	2	hSpCas9	negative selection	8705113
180230578	180230601	1	-	27260156	PATU8988T	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.5915859195716153	[229]	[44,243,149,160]	-7	hSpCas9	negative selection	8705114
180266583	180266606	1	-	27260156	PATU8988T	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.7528825220247823	[605]	[1401,883,754,891]	9	hSpCas9	negative selection	8769368
180230535	180230558	1	+	27260156	PATU8988T	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.3106050148053501	[161]	[92,111,238,51]	-5	hSpCas9	negative selection	8769369
180248292	180248315	1	-	27260156	PATU8988T	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.3084484399349473	[300]	[399,274,152,105]	-5	hSpCas9	negative selection	8769370
180266392	180266415	1	+	27260156	T47D	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.32179580905174865	[222]	[389,259,320,333]	6	hSpCas9	negative selection	8826363
180248388	180248411	1	-	27260156	T47D	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.19688144273416744	[361]	[465,485,514,464]	4	hSpCas9	negative selection	8826364
180230578	180230601	1	-	27260156	T47D	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.20595389006824116	[229]	[220,214,182,314]	-4	hSpCas9	negative selection	8826365
180266583	180266606	1	-	27260156	T47D	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.4002698975869543	[605]	[1153,767,897,921]	8	hSpCas9	negative selection	8890619
180230535	180230558	1	+	27260156	T47D	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.495039447378848	[161]	[157,116,92,170]	-8	hSpCas9	negative selection	8890620
180248292	180248315	1	-	27260156	T47D	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.4918178141907088	[300]	[317,154,269,262]	-8	hSpCas9	negative selection	8890621
180266392	180266415	1	+	27260156	SU8686	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.23942115515555296	[222]	[241,271,217,318]	4	hSpCas9	negative selection	8947614
180248388	180248411	1	-	27260156	SU8686	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.526208682902557	[361]	[425,473,484,727]	8	hSpCas9	negative selection	8947615
180230578	180230601	1	-	27260156	SU8686	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	0.0030726614547795794	[229]	[166,190,299,275]	0	hSpCas9	negative selection	8947616
180266583	180266606	1	-	27260156	SU8686	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.47663026881344195	[605]	[672,778,900,1046]	7	hSpCas9	negative selection	9011870
180230535	180230558	1	+	27260156	SU8686	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.4584570465494393	[161]	[119,124,126,88]	-6	hSpCas9	negative selection	9011871
180248292	180248315	1	-	27260156	SU8686	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.26653427253194983	[300]	[142,208,350,318]	-4	hSpCas9	negative selection	9011872
180266392	180266415	1	+	27260156	SKES1	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.4801674555367652	[222]	[412,387,301,174]	8	hSpCas9	negative selection	9068865
180248388	180248411	1	-	27260156	SKES1	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.018377091675775614	[361]	[533,469,282,225]	0	hSpCas9	negative selection	9068866
180230578	180230601	1	-	27260156	SKES1	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.041034460867465095	[229]	[272,274,163,194]	-1	hSpCas9	negative selection	9068867
180266583	180266606	1	-	27260156	SKES1	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.2684903259027469	[605]	[736,860,661,669]	5	hSpCas9	negative selection	9133121
180230535	180230558	1	+	27260156	SKES1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.9450591439310827	[161]	[47,74,107,95]	-9	hSpCas9	negative selection	9133122
180248292	180248315	1	-	27260156	SKES1	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.45349159906746483	[300]	[210,274,207,189]	-7	hSpCas9	negative selection	9133123
180266392	180266415	1	+	27260156	TOV112D	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.2620233450622853	[222]	[371,287,279,147]	5	hSpCas9	negative selection	9190116
180248388	180248411	1	-	27260156	TOV112D	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	-0.18424575474583882	[361]	[208,391,381,301]	-4	hSpCas9	negative selection	9190117
180230578	180230601	1	-	27260156	TOV112D	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.0712575852806554	[229]	[178,274,322,112]	-1	hSpCas9	negative selection	9190118
180266583	180266606	1	-	27260156	TOV112D	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.363858326295476	[605]	[876,1000,630,678]	7	hSpCas9	negative selection	9254372
180230535	180230558	1	+	27260156	TOV112D	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.6641773810055982	[161]	[113,121,69,108]	-8	hSpCas9	negative selection	9254373
180248292	180248315	1	-	27260156	TOV112D	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.03140779848120645	[300]	[180,461,130,432]	0	hSpCas9	negative selection	9254374
180266392	180266415	1	+	27260156	TC71	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	-0.03949186971105245	[222]	[246,226,176,283]	-1	hSpCas9	negative selection	9311367
180248388	180248411	1	-	27260156	TC71	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.28993880704898467	[361]	[540,474,420,459]	7	hSpCas9	negative selection	9311368
180230578	180230601	1	-	27260156	TC71	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.22347517029848074	[229]	[237,193,194,217]	-5	hSpCas9	negative selection	9311369
180266583	180266606	1	-	27260156	TC71	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.2529423405142667	[605]	[799,792,770,728]	6	hSpCas9	negative selection	9375623
180230535	180230558	1	+	27260156	TC71	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.25586745265548183	[161]	[133,188,183,68]	-6	hSpCas9	negative selection	9375624
180248292	180248315	1	-	27260156	TC71	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.33469886109095004	[300]	[273,240,262,243]	-7	hSpCas9	negative selection	9375625
180266392	180266415	1	+	27260156	TC32	viability	GCGCTTCGGCACAAAATGCACGG	LHX4	ENSG00000121454	0.2456411352129233	[222]	[221,260,275,219]	4	hSpCas9	negative selection	9432618
180248388	180248411	1	-	27260156	TC32	viability	ACCTGTCCGCCAGCTGCATCTGG	LHX4	ENSG00000121454	0.23990608798638016	[361]	[424,154,450,668]	4	hSpCas9	negative selection	9432619
180230578	180230601	1	-	27260156	TC32	viability	ATCGGCACACCTAGCATCTCCGG	LHX4	ENSG00000121454	-0.4215847166044375	[229]	[142,142,234,134]	-7	hSpCas9	negative selection	9432620
180266583	180266606	1	-	27260156	TC32	viability	ATGCTGCTTACCGTTCTGCTTGG	LHX4	ENSG00000121454	0.42109271435131346	[605]	[698,748,709,850]	7	hSpCas9	negative selection	9496874
180230535	180230558	1	+	27260156	TC32	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.7551548231207157	[161]	[77,48,121,131]	-9	hSpCas9	negative selection	9496875
180248292	180248315	1	-	27260156	TC32	viability	GCTGGTTGCAGCCAGCGCACTGG	LHX4	ENSG00000121454	-0.5672047263691202	[300]	[170,134,234,245]	-8	hSpCas9	negative selection	9496876
180248387	180248410	1	+	27869803	HPAFII	viability after 27 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	1.6494786004529682	[83]	[35,223,NaN]	9	hSpCas9	negative selection	9530825
180266487	180266510	1	+	27869803	HPAFII	viability after 27 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.264984896836773	[234]	[38,155,NaN]	-2	hSpCas9	negative selection	9530826
180248387	180248410	1	+	27869803	HPAFII	viability after 15 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.8518420959344791	[83]	[157,165,NaN]	8	hSpCas9	negative selection	9613274
180266487	180266510	1	+	27869803	HPAFII	viability after 15 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.09046870569660655	[234]	[169,278,NaN]	-1	hSpCas9	negative selection	9613275
180248387	180248410	1	+	27869803	ASPC1	viability after 36 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-1.2011645509529072	[264]	[86,9,30]	-8	hSpCas9	negative selection	9695723
180266487	180266510	1	+	27869803	ASPC1	viability after 36 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.8459237045862307	[474]	[56,90,116]	-7	hSpCas9	negative selection	9695724
180248387	180248410	1	+	27869803	PATU8988S	viability after 35 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	-0.3067647664482458	[217]	[62,78,NaN]	-3	hSpCas9	negative selection	9778172
180266487	180266510	1	+	27869803	PATU8988S	viability after 35 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.7286579241205738	[304]	[227,178,NaN]	7	hSpCas9	negative selection	9778173
180248387	180248410	1	+	27869803	PATU8988S	viability after 31 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	0.34374089530361207	[217]	[75,153,NaN]	4	hSpCas9	negative selection	9860621
180266487	180266510	1	+	27869803	PATU8988S	viability after 31 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	0.5250128708320843	[304]	[174,174,NaN]	6	hSpCas9	negative selection	9860622
180248387	180248410	1	+	27869803	HPAFII	viability after 35 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	2.296147704485	[83]	[39,398,NaN]	9	hSpCas9	negative selection	9943070
180266487	180266510	1	+	27869803	HPAFII	viability after 35 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.3935432255846905	[234]	[43,142,NaN]	-2	hSpCas9	negative selection	9943071
180248387	180248410	1	+	27869803	HPAFII	viability after 31 days	GCCAGATGCAGCTGGCGGACAGG	LHX4	ENSG00000121454	1.8287018819502274	[83]	[65,277,NaN]	9	hSpCas9	negative selection	10025519
180266487	180266510	1	+	27869803	HPAFII	viability after 31 days	TTGCTTGCATCATCTGCAACCGG	LHX4	ENSG00000121454	-0.41191671247736183	[234]	[34,168,NaN]	-3	hSpCas9	negative selection	10025520
180248424	180248447	1	+	28162770	P31FUJ	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.5839759715298511	[108]	[191]	6	hSpCas9	negative selection	10184327
180266524	180266547	1	+	28162770	P31FUJ	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.2266294142229186	[47]	[65]	2	hSpCas9	negative selection	10184328
180230535	180230558	1	+	28162770	P31FUJ	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.30052913973461703	[784]	[748]	-3	hSpCas9	negative selection	10184329
180248281	180248304	1	+	28162770	P31FUJ	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.05298132673788891	[387]	[472]	0	hSpCas9	negative selection	10184330
180248382	180248405	1	+	28162770	P31FUJ	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	1.1042327828631922	[18]	[47]	9	hSpCas9	negative selection	10184331
180266440	180266463	1	+	28162770	P31FUJ	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.3710193235580935	[151]	[230]	4	hSpCas9	negative selection	10184332
180248424	180248447	1	+	28162770	TF1	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	NaN	[NaN]	[358]	1	hSpCas9	negative selection	10353693
180266524	180266547	1	+	28162770	TF1	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	NaN	[NaN]	[107]	1	hSpCas9	negative selection	10353694
180230535	180230558	1	+	28162770	TF1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	NaN	[NaN]	[539]	1	hSpCas9	negative selection	10353695
180248281	180248304	1	+	28162770	TF1	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	NaN	[NaN]	[296]	1	hSpCas9	negative selection	10353696
180248382	180248405	1	+	28162770	TF1	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10353697
180266440	180266463	1	+	28162770	TF1	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	NaN	[NaN]	[31]	1	hSpCas9	negative selection	10353698
180248424	180248447	1	+	28162770	SKM1	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.8602580040540657	[42]	[137]	7	hSpCas9	negative selection	10523059
180266524	180266547	1	+	28162770	SKM1	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.9622696109225573	[17]	[61]	8	hSpCas9	negative selection	10523060
180230535	180230558	1	+	28162770	SKM1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.183898903417679	[121]	[244]	1	hSpCas9	negative selection	10523061
180248281	180248304	1	+	28162770	SKM1	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-0.5667446427799312	[92]	[110]	-4	hSpCas9	negative selection	10523062
180248382	180248405	1	+	28162770	SKM1	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.4999263968653569	[1]	[4]	5	hSpCas9	negative selection	10523063
180266440	180266463	1	+	28162770	SKM1	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.7629608026991507	[32]	[98]	7	hSpCas9	negative selection	10523064
180248424	180248447	1	+	28162770	SKM1	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.8602580040540657	[42]	[137]	7	hSpCas9	negative selection	10692425
180266524	180266547	1	+	28162770	SKM1	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.9622696109225573	[17]	[61]	8	hSpCas9	negative selection	10692426
180230535	180230558	1	+	28162770	SKM1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.183898903417679	[121]	[244]	1	hSpCas9	negative selection	10692427
180248281	180248304	1	+	28162770	SKM1	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-0.5667446427799312	[92]	[110]	-4	hSpCas9	negative selection	10692428
180248382	180248405	1	+	28162770	SKM1	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.4999263968653569	[1]	[4]	5	hSpCas9	negative selection	10692429
180266440	180266463	1	+	28162770	SKM1	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.7629608026991507	[32]	[98]	7	hSpCas9	negative selection	10692430
180248424	180248447	1	+	28162770	PL21	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	-0.5397084882100073	[166]	[49]	-4	hSpCas9	negative selection	10861791
180266524	180266547	1	+	28162770	PL21	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	1.2386137623039557	[110]	[113]	8	hSpCas9	negative selection	10861792
180230535	180230558	1	+	28162770	PL21	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.542120279346399	[454]	[135]	-4	hSpCas9	negative selection	10861793
180248281	180248304	1	+	28162770	PL21	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.06137554453346841	[228]	[103]	0	hSpCas9	negative selection	10861794
180248382	180248405	1	+	28162770	PL21	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.9777471931528718	[6]	[5]	7	hSpCas9	negative selection	10861795
180266440	180266463	1	+	28162770	PL21	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	-0.5321646023070229	[102]	[30]	-4	hSpCas9	negative selection	10861796
180248424	180248447	1	+	28162770	P31FUJ	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.5839759715298511	[108]	[191]	6	hSpCas9	negative selection	11031157
180266524	180266547	1	+	28162770	P31FUJ	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.2266294142229186	[47]	[65]	2	hSpCas9	negative selection	11031158
180230535	180230558	1	+	28162770	P31FUJ	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.30052913973461703	[784]	[748]	-3	hSpCas9	negative selection	11031159
180248281	180248304	1	+	28162770	P31FUJ	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.05298132673788891	[387]	[472]	0	hSpCas9	negative selection	11031160
180248382	180248405	1	+	28162770	P31FUJ	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	1.1042327828631922	[18]	[47]	9	hSpCas9	negative selection	11031161
180266440	180266463	1	+	28162770	P31FUJ	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.3710193235580935	[151]	[230]	4	hSpCas9	negative selection	11031162
180248424	180248447	1	+	28162770	OCIAML5	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.06281681549805221	[95]	[180]	0	hSpCas9	negative selection	11200523
180266524	180266547	1	+	28162770	OCIAML5	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.5119869996960418	[53]	[138]	4	hSpCas9	negative selection	11200524
180230535	180230558	1	+	28162770	OCIAML5	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.6490795487001421	[277]	[319]	-4	hSpCas9	negative selection	11200525
180248281	180248304	1	+	28162770	OCIAML5	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.07907157099119871	[117]	[224]	0	hSpCas9	negative selection	11200526
180248382	180248405	1	+	28162770	OCIAML5	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.5539257888118398	[19]	[52]	5	hSpCas9	negative selection	11200527
180266440	180266463	1	+	28162770	OCIAML5	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	-0.36143145269099397	[78]	[110]	-3	hSpCas9	negative selection	11200528
180248424	180248447	1	+	28162770	EOL1	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	-0.4851759278118415	[270]	[101]	-4	hSpCas9	negative selection	11369889
180266524	180266547	1	+	28162770	EOL1	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.17416166164200675	[179]	[106]	1	hSpCas9	negative selection	11369890
180230535	180230558	1	+	28162770	EOL1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.7548968123060598	[657]	[584]	6	hSpCas9	negative selection	11369891
180248281	180248304	1	+	28162770	EOL1	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.05781430243399871	[371]	[203]	0	hSpCas9	negative selection	11369892
180248382	180248405	1	+	28162770	EOL1	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	-0.8828071504870696	[20]	[5]	-6	hSpCas9	negative selection	11369893
180266440	180266463	1	+	28162770	EOL1	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	-1.1673747178705045	[161]	[37]	-7	hSpCas9	negative selection	11369894
180248424	180248447	1	+	28162770	MOLM13	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	-0.08504426498393947	[244]	[166]	0	hSpCas9	negative selection	11539255
180266524	180266547	1	+	28162770	MOLM13	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	-1.181203456596293	[137]	[43]	-6	hSpCas9	negative selection	11539256
180230535	180230558	1	+	28162770	MOLM13	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.5143486926372389	[549]	[567]	4	hSpCas9	negative selection	11539257
180248281	180248304	1	+	28162770	MOLM13	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-1.0536477390349437	[444]	[154]	-5	hSpCas9	negative selection	11539258
180248382	180248405	1	+	28162770	MOLM13	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.9824625543743366	[6]	[9]	7	hSpCas9	negative selection	11539259
180266440	180266463	1	+	28162770	MOLM13	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	1.3111638778571255	[101]	[182]	8	hSpCas9	negative selection	11539260
180248424	180248447	1	+	28162770	HEL	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	1.4377868586063478	[184]	[320]	9	hSpCas9	negative selection	11708621
180266524	180266547	1	+	28162770	HEL	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.043276761584085666	[99]	[65]	0	hSpCas9	negative selection	11708622
180230535	180230558	1	+	28162770	HEL	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.4728138305580446	[422]	[375]	4	hSpCas9	negative selection	11708623
180248281	180248304	1	+	28162770	HEL	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-0.1362908217323932	[289]	[168]	-1	hSpCas9	negative selection	11708624
180248382	180248405	1	+	28162770	HEL	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	1.6427388320003566	[13]	[27]	9	hSpCas9	negative selection	11708625
180266440	180266463	1	+	28162770	HEL	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	-0.06508041650633278	[97]	[59]	0	hSpCas9	negative selection	11708626
180248424	180248447	1	+	28162770	MV411	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.13361765122561337	[144]	[133]	1	hSpCas9	negative selection	11877987
180266524	180266547	1	+	28162770	MV411	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	-0.4774552110828558	[118]	[71]	-4	hSpCas9	negative selection	11877988
180230535	180230558	1	+	28162770	MV411	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.04432857359433462	[425]	[347]	0	hSpCas9	negative selection	11877989
180248281	180248304	1	+	28162770	MV411	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-0.06290256982937514	[278]	[224]	0	hSpCas9	negative selection	11877990
180248382	180248405	1	+	28162770	MV411	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	0.1319603333628394	[12]	[11]	1	hSpCas9	negative selection	11877991
180266440	180266463	1	+	28162770	MV411	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.8038308993071606	[84]	[124]	7	hSpCas9	negative selection	11877992
180248424	180248447	1	+	28162770	MONOMAC1	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	-0.3490399405046036	[99]	[89]	-3	hSpCas9	negative selection	12047353
180266524	180266547	1	+	28162770	MONOMAC1	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	0.15211271656283287	[83]	[106]	1	hSpCas9	negative selection	12047354
180230535	180230558	1	+	28162770	MONOMAC1	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.1986723912848687	[262]	[345]	2	hSpCas9	negative selection	12047355
180248281	180248304	1	+	28162770	MONOMAC1	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	0.9783302394510066	[146]	[331]	8	hSpCas9	negative selection	12047356
180248382	180248405	1	+	28162770	MONOMAC1	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	-1.1970368470595534	[9]	[4]	-7	hSpCas9	negative selection	12047357
180266440	180266463	1	+	28162770	MONOMAC1	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	-0.36053557934243297	[55]	[49]	-3	hSpCas9	negative selection	12047358
180248424	180248447	1	+	28162770	OCIAML2	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.609743591221859	[23]	[202]	6	hSpCas9	negative selection	12216719
180266524	180266547	1	+	28162770	OCIAML2	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	-0.6462013898256156	[23]	[84]	-5	hSpCas9	negative selection	12216720
180230535	180230558	1	+	28162770	OCIAML2	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	0.07956725731831826	[62]	[368]	0	hSpCas9	negative selection	12216721
180248281	180248304	1	+	28162770	OCIAML2	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-1.0921182019884317	[44]	[116]	-6	hSpCas9	negative selection	12216722
180248382	180248405	1	+	28162770	OCIAML2	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	1.5293701747578385	[0]	[15]	9	hSpCas9	negative selection	12216723
180266440	180266463	1	+	28162770	OCIAML2	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	0.17962413573071434	[17]	[112]	1	hSpCas9	negative selection	12216724
180248424	180248447	1	+	28162770	OCIAML3	viability	TGGGAGCGTCTACTGCAAGGAGG	LHX4	ENSG00000121454	0.4258919171135418	[35]	[145]	4	hSpCas9	negative selection	12386085
180266524	180266547	1	+	28162770	OCIAML3	viability	GGACGAATTCTACCTCATGGAGG	LHX4	ENSG00000121454	-1.1310356639816173	[36]	[50]	-7	hSpCas9	negative selection	12386086
180230535	180230558	1	+	28162770	OCIAML3	viability	GCAGAGTGCGACTGTCCCCGCGG	LHX4	ENSG00000121454	-0.28866242963240474	[139]	[345]	-2	hSpCas9	negative selection	12386087
180248281	180248304	1	+	28162770	OCIAML3	viability	ACAGAGATTCCCCAGTGCGCTGG	LHX4	ENSG00000121454	-0.14959553891180571	[78]	[214]	-1	hSpCas9	negative selection	12386088
180248382	180248405	1	+	28162770	OCIAML3	viability	AGACTGCCAGATGCAGCTGGCGG	LHX4	ENSG00000121454	2.8654239783131334	[2]	[65]	9	hSpCas9	negative selection	12386089
180266440	180266463	1	+	28162770	OCIAML3	viability	CCAGGTGGTCCGCAAGGCCCAGG	LHX4	ENSG00000121454	-0.594007640324163	[30]	[61]	-4	hSpCas9	negative selection	12386090