Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:431707
• Symbol:LHX8
• Description:LIM homeobox 8

DataSource: http://genomecrispr.dkfz.de/#!/results/LHX8

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
75136648	75136671	1	+	26472758	Jiyoye	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.9871035576061727	[91]	[34]	-6	hSpCas9	negative selection	90421
75137213	75137236	1	+	26472758	Jiyoye	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.6157620033172906	[89]	[103]	4	hSpCas9	negative selection	90422
75137096	75137119	1	+	26472758	Jiyoye	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	0.06506940468088063	[89]	[70]	0	hSpCas9	negative selection	90423
75141019	75141042	1	-	26472758	Jiyoye	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	1.009519960455266	[109]	[166]	6	hSpCas9	negative selection	90424
75136626	75136649	1	+	26472758	Jiyoye	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	2.7370962671467662	[35]	[180]	9	hSpCas9	negative selection	90425
75137148	75137171	1	-	26472758	Jiyoye	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	0.1795080181287513	[136]	[116]	1	hSpCas9	negative selection	90426
75137169	75137192	1	-	26472758	Jiyoye	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.6943626449561889	[102]	[47]	-5	hSpCas9	negative selection	90427
75156974	75156997	1	-	26472758	Jiyoye	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-2.7627496199364394	[26]	[2]	-9	hSpCas9	negative selection	90428
75157055	75157078	1	+	26472758	Jiyoye	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.5390870570114545	[93]	[102]	4	hSpCas9	negative selection	90429
75136609	75136632	1	+	26472758	Jiyoye	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.461580085215874	[83]	[45]	-3	hSpCas9	negative selection	90430
75136648	75136671	1	+	26472758	KBM7	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.20729126170503842	[175,197]	[90,112]	2	hSpCas9	negative selection	281539
75137213	75137236	1	+	26472758	KBM7	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.5094273753100372	[575,452]	[297,380]	5	hSpCas9	negative selection	281540
75137096	75137119	1	+	26472758	KBM7	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	-0.011620650533731958	[343,170]	[105,125]	0	hSpCas9	negative selection	281541
75141019	75141042	1	-	26472758	KBM7	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.18280614291143027	[814,522]	[325,372]	1	hSpCas9	negative selection	281542
75136626	75136649	1	+	26472758	KBM7	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.0162573930879988	[352,341]	[254,399]	9	hSpCas9	negative selection	281543
75137148	75137171	1	-	26472758	KBM7	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	0.25720232396601145	[541,439]	[371,186]	2	hSpCas9	negative selection	281544
75137169	75137192	1	-	26472758	KBM7	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	1.2846620366831194	[134,197]	[169,217]	9	hSpCas9	negative selection	281545
75156974	75156997	1	-	26472758	KBM7	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-3.57056438807518	[86,103]	[6,0]	-9	hSpCas9	negative selection	281546
75157055	75157078	1	+	26472758	KBM7	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	-0.2379062641164325	[511,380]	[190,162]	-2	hSpCas9	negative selection	281547
75136609	75136632	1	+	26472758	KBM7	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	1.5405590340593855	[280,159]	[235,346]	9	hSpCas9	negative selection	281548
75136648	75136671	1	+	26472758	Raji	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.4935661719802581	[100]	[32]	5	hSpCas9	negative selection	472657
75137213	75137236	1	+	26472758	Raji	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.1990140108391677	[243]	[64]	1	hSpCas9	negative selection	472658
75137096	75137119	1	+	26472758	Raji	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	-1.6130939360040375	[144]	[10]	-8	hSpCas9	negative selection	472659
75141019	75141042	1	-	26472758	Raji	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	-0.047552291849259576	[382]	[85]	0	hSpCas9	negative selection	472660
75136626	75136649	1	+	26472758	Raji	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.653665567930696	[125]	[91]	9	hSpCas9	negative selection	472661
75137148	75137171	1	-	26472758	Raji	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-0.3076539639052444	[175]	[32]	-3	hSpCas9	negative selection	472662
75137169	75137192	1	-	26472758	Raji	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	2.1329186274807372	[55]	[56]	9	hSpCas9	negative selection	472663
75156974	75156997	1	-	26472758	Raji	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-0.12965566192724998	[32]	[6]	-1	hSpCas9	negative selection	472664
75157055	75157078	1	+	26472758	Raji	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.6115734123892254	[250]	[88]	6	hSpCas9	negative selection	472665
75136609	75136632	1	+	26472758	Raji	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	1.216612605128358	[88]	[47]	9	hSpCas9	negative selection	472666
75136648	75136671	1	+	26472758	K562	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.5392633654067895	[135]	[78]	-3	hSpCas9	negative selection	663775
75137213	75137236	1	+	26472758	K562	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.4611535141409689	[437]	[508]	3	hSpCas9	negative selection	663776
75137096	75137119	1	+	26472758	K562	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	-0.5167944127464367	[299]	[176]	-3	hSpCas9	negative selection	663777
75141019	75141042	1	-	26472758	K562	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.6935673730418832	[511]	[698]	6	hSpCas9	negative selection	663778
75136626	75136649	1	+	26472758	K562	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.8077362343476231	[290]	[429]	6	hSpCas9	negative selection	663779
75137148	75137171	1	-	26472758	K562	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-0.6438561897747247	[384]	[207]	-4	hSpCas9	negative selection	663780
75137169	75137192	1	-	26472758	K562	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.0051951624050252665	[213]	[179]	0	hSpCas9	negative selection	663781
75156974	75156997	1	-	26472758	K562	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-5.94540583121357	[72]	[0]	-9	hSpCas9	negative selection	663782
75157055	75157078	1	+	26472758	K562	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.034965362037497005	[406]	[351]	0	hSpCas9	negative selection	663783
75136609	75136632	1	+	26472758	K562	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	1.3012499502631232	[223]	[465]	9	hSpCas9	negative selection	663784
75136656	75136679	1	+	26627737	DLD1	viability	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.2999621964524528	[93]	[31,47,29]	3	hSpCas9	negative selection	772600
75137213	75137236	1	+	26627737	DLD1	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	1.0483436483148352	[131]	[160,14,77]	8	hSpCas9	negative selection	772601
75143232	75143255	1	+	26627737	DLD1	viability	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.3121706738254767	[544]	[306,174,158]	3	hSpCas9	negative selection	772602
75143923	75143946	1	-	26627737	DLD1	viability	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.19790328710745397	[926]	[314,379,307]	2	hSpCas9	negative selection	772603
75156981	75157004	1	-	26627737	DLD1	viability	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.511944762603781	[234]	[136,118,64]	5	hSpCas9	negative selection	772604
75136656	75136679	1	+	26627737	GBM cells	viability after 5 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-0.49187607814648127	[58]	[19,24]	-7	hSpCas9	negative selection	854915
75137213	75137236	1	+	26627737	GBM cells	viability after 5 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.5926981495007615	[186]	[59,72]	-7	hSpCas9	negative selection	854916
75143232	75143255	1	+	26627737	GBM cells	viability after 5 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.0857788723264662	[374]	[190,187]	-1	hSpCas9	negative selection	854917
75143923	75143946	1	-	26627737	GBM cells	viability after 5 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.125523472685642	[487]	[254,315]	2	hSpCas9	negative selection	854918
75156981	75157004	1	-	26627737	GBM cells	viability after 5 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.22769564081411042	[167]	[97,112]	3	hSpCas9	negative selection	854919
75136656	75136679	1	+	26627737	GBM cells	viability after 13 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.3421884031579625	[58]	[28,49]	4	hSpCas9	negative selection	937230
75137213	75137236	1	+	26627737	GBM cells	viability after 13 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.698497954997384	[186]	[72,53]	-7	hSpCas9	negative selection	937231
75143232	75143255	1	+	26627737	GBM cells	viability after 13 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.10584007415493246	[374]	[198,180]	-1	hSpCas9	negative selection	937232
75143923	75143946	1	-	26627737	GBM cells	viability after 13 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.5814990492894265	[487]	[409,384]	7	hSpCas9	negative selection	937233
75156981	75157004	1	-	26627737	GBM cells	viability after 13 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.872155429565654	[167]	[205,134]	8	hSpCas9	negative selection	937234
75136656	75136679	1	+	26627737	GBM cells	viability after 21 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-2.306910772875361	[58]	[6,5]	-9	hSpCas9	negative selection	1019545
75137213	75137236	1	+	26627737	GBM cells	viability after 21 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.1555234847611004	[186]	[97,84]	-1	hSpCas9	negative selection	1019546
75143232	75143255	1	+	26627737	GBM cells	viability after 21 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.11532789786929543	[374]	[197,178]	-1	hSpCas9	negative selection	1019547
75143923	75143946	1	-	26627737	GBM cells	viability after 21 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.7630634048375509	[487]	[474,426]	7	hSpCas9	negative selection	1019548
75156981	75157004	1	-	26627737	GBM cells	viability after 21 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.8133462676305677	[167]	[162,157]	7	hSpCas9	negative selection	1019549
75136656	75136679	1	+	26627737	RPE1	viability after 9 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-2.1641979296992897	[636]	[40,48]	-9	hSpCas9	negative selection	1101860
75137213	75137236	1	+	26627737	RPE1	viability after 9 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.1757241553763455	[1145]	[228,431]	-1	hSpCas9	negative selection	1101861
75143232	75143255	1	+	26627737	RPE1	viability after 9 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.19951115204537645	[1136]	[178,478]	-1	hSpCas9	negative selection	1101862
75143923	75143946	1	-	26627737	RPE1	viability after 9 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.8088171087779372	[1814]	[973,1022]	5	hSpCas9	negative selection	1101863
75156981	75157004	1	-	26627737	RPE1	viability after 9 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	2.827893667494457	[166]	[296,466]	9	hSpCas9	negative selection	1101864
75136656	75136679	1	+	26627737	RPE1	viability after 12 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-5.806854181126982	[636]	[4,0]	-9	hSpCas9	negative selection	1184175
75137213	75137236	1	+	26627737	RPE1	viability after 12 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-1.2805192838670238	[1145]	[83,171]	-7	hSpCas9	negative selection	1184176
75143232	75143255	1	+	26627737	RPE1	viability after 12 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.02101159035211475	[1136]	[336,262]	0	hSpCas9	negative selection	1184177
75143923	75143946	1	-	26627737	RPE1	viability after 12 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.6668668333392154	[1814]	[796,749]	4	hSpCas9	negative selection	1184178
75156981	75157004	1	-	26627737	RPE1	viability after 12 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	2.256375945156245	[166]	[209,218]	9	hSpCas9	negative selection	1184179
75136656	75136679	1	+	26627737	RPE1	viability after 15 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-3.8360296921351993	[636]	[5,18]	-9	hSpCas9	negative selection	1266490
75137213	75137236	1	+	26627737	RPE1	viability after 15 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.2640565661303385	[1145]	[187,348]	-2	hSpCas9	negative selection	1266491
75143232	75143255	1	+	26627737	RPE1	viability after 15 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.21044381710620597	[1136]	[335,406]	1	hSpCas9	negative selection	1266492
75143923	75143946	1	-	26627737	RPE1	viability after 15 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.6547679221882876	[1814]	[874,743]	4	hSpCas9	negative selection	1266493
75156981	75157004	1	-	26627737	RPE1	viability after 15 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	2.3904630139026106	[166]	[292,203]	9	hSpCas9	negative selection	1266494
75136656	75136679	1	+	26627737	RPE1	viability after 18 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-2.6222836532001184	[636]	[10,45]	-8	hSpCas9	negative selection	1348805
75137213	75137236	1	+	26627737	RPE1	viability after 18 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.9993804227812986	[1145]	[145,163]	-6	hSpCas9	negative selection	1348806
75143232	75143255	1	+	26627737	RPE1	viability after 18 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.020081898554347166	[1136]	[358,259]	0	hSpCas9	negative selection	1348807
75143923	75143946	1	-	26627737	RPE1	viability after 18 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.7997551483299952	[1814]	[842,862]	5	hSpCas9	negative selection	1348808
75156981	75157004	1	-	26627737	RPE1	viability after 18 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	2.3927152014439215	[166]	[299,168]	9	hSpCas9	negative selection	1348809
75136656	75136679	1	+	26627737	HeLa	viability after 8 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-0.15550318818099873	[186]	[193,55,0]	-1	hSpCas9	negative selection	1431120
75137213	75137236	1	+	26627737	HeLa	viability after 8 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.2690852558852423	[472]	[233,288,219]	2	hSpCas9	negative selection	1431121
75143232	75143255	1	+	26627737	HeLa	viability after 8 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.14641296038849094	[624]	[306,158,281]	-1	hSpCas9	negative selection	1431122
75143923	75143946	1	-	26627737	HeLa	viability after 8 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.2673101926340028	[559]	[426,273,213]	2	hSpCas9	negative selection	1431123
75156981	75157004	1	-	26627737	HeLa	viability after 8 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	-0.002084979720981761	[265]	[18,168,135]	0	hSpCas9	negative selection	1431124
75136656	75136679	1	+	26627737	HeLa	viability after 12 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.6250448150329905	[186]	[157,153,42]	5	hSpCas9	negative selection	1513435
75137213	75137236	1	+	26627737	HeLa	viability after 12 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.4363167555756042	[472]	[163,439,167]	4	hSpCas9	negative selection	1513436
75143232	75143255	1	+	26627737	HeLa	viability after 12 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.38831539659545145	[624]	[451,257,315]	3	hSpCas9	negative selection	1513437
75143923	75143946	1	-	26627737	HeLa	viability after 12 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.6397572100030743	[559]	[343,296,446]	5	hSpCas9	negative selection	1513438
75156981	75157004	1	-	26627737	HeLa	viability after 12 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.08799257862877463	[265]	[45,158,138]	0	hSpCas9	negative selection	1513439
75136656	75136679	1	+	26627737	HeLa	viability after 15 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.5884210233953742	[186]	[221,53,61]	5	hSpCas9	negative selection	1595750
75137213	75137236	1	+	26627737	HeLa	viability after 15 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.5864838668046306	[472]	[356,202,307]	5	hSpCas9	negative selection	1595751
75143232	75143255	1	+	26627737	HeLa	viability after 15 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.04468345982487354	[624]	[159,275,309]	0	hSpCas9	negative selection	1595752
75143923	75143946	1	-	26627737	HeLa	viability after 15 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.79424042378987	[559]	[359,388,440]	6	hSpCas9	negative selection	1595753
75156981	75157004	1	-	26627737	HeLa	viability after 15 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.734174973287335	[265]	[250,77,212]	6	hSpCas9	negative selection	1595754
75136656	75136679	1	+	26627737	HeLa	viability after 18 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.6423121883273097	[186]	[157,43,61]	5	hSpCas9	negative selection	1678065
75137213	75137236	1	+	26627737	HeLa	viability after 18 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.5579702459325473	[472]	[238,154,307]	4	hSpCas9	negative selection	1678066
75143232	75143255	1	+	26627737	HeLa	viability after 18 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.02729836478240666	[624]	[111,229,309]	0	hSpCas9	negative selection	1678067
75143923	75143946	1	-	26627737	HeLa	viability after 18 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.7881682698443843	[559]	[235,324,440]	6	hSpCas9	negative selection	1678068
75156981	75157004	1	-	26627737	HeLa	viability after 18 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.7371295218932993	[265]	[167,65,212]	6	hSpCas9	negative selection	1678069
75136656	75136679	1	+	26627737	HCT116	viability after 6 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	3.9076800900700164	[53]	[352,2]	9	hSpCas9	negative selection	1760380
75137213	75137236	1	+	26627737	HCT116	viability after 6 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.7193432186059007	[418]	[72,127]	4	hSpCas9	negative selection	1760381
75143232	75143255	1	+	26627737	HCT116	viability after 6 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.3119715025683947	[893]	[303,7]	-2	hSpCas9	negative selection	1760382
75143923	75143946	1	-	26627737	HCT116	viability after 6 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	1.6610958242342362	[817]	[387,416]	8	hSpCas9	negative selection	1760383
75156981	75157004	1	-	26627737	HCT116	viability after 6 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	-1.7472068404749421	[578]	[10,35]	-7	hSpCas9	negative selection	1760384
75136656	75136679	1	+	26627737	HCT116	viability after 8 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-0.42218437155565725	[111]	[68,57,11]	-5	hSpCas9	negative selection	1842695
75137213	75137236	1	+	26627737	HCT116	viability after 8 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.7553367575673132	[368]	[112,108,138]	-7	hSpCas9	negative selection	1842696
75143232	75143255	1	+	26627737	HCT116	viability after 8 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.5016123005145636	[276]	[184,267,194]	5	hSpCas9	negative selection	1842697
75143923	75143946	1	-	26627737	HCT116	viability after 8 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.6747393455248447	[375]	[335,383,272]	6	hSpCas9	negative selection	1842698
75156981	75157004	1	-	26627737	HCT116	viability after 8 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.1079332726971432	[215]	[179,99,105]	1	hSpCas9	negative selection	1842699
75136656	75136679	1	+	26627737	HCT116	viability after 9 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	2.822272780559139	[53]	[1,180]	9	hSpCas9	negative selection	1925010
75137213	75137236	1	+	26627737	HCT116	viability after 9 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	1.1889954681620098	[418]	[239,266]	7	hSpCas9	negative selection	1925011
75143232	75143255	1	+	26627737	HCT116	viability after 9 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.19951404875945628	[893]	[332,108]	-1	hSpCas9	negative selection	1925012
75143923	75143946	1	-	26627737	HCT116	viability after 9 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.9256244315139677	[817]	[558,300]	6	hSpCas9	negative selection	1925013
75156981	75157004	1	-	26627737	HCT116	viability after 9 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	-1.240297105694959	[578]	[65,64]	-7	hSpCas9	negative selection	1925014
75136656	75136679	1	+	26627737	HCT116	viability after 12 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-1.0461810684122352	[111]	[37,41,4]	-8	hSpCas9	negative selection	2007325
75137213	75137236	1	+	26627737	HCT116	viability after 12 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.07794863247761796	[368]	[175,180,258]	0	hSpCas9	negative selection	2007326
75143232	75143255	1	+	26627737	HCT116	viability after 12 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.5585887739927935	[276]	[131,319,200]	5	hSpCas9	negative selection	2007327
75143923	75143946	1	-	26627737	HCT116	viability after 12 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.9148581031797547	[375]	[308,321,490]	7	hSpCas9	negative selection	2007328
75156981	75157004	1	-	26627737	HCT116	viability after 12 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.3527743454135873	[215]	[136,79,216]	3	hSpCas9	negative selection	2007329
75136656	75136679	1	+	26627737	HCT116	viability after 15 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-0.47483792153246895	[111]	[85,37,19]	-5	hSpCas9	negative selection	2089640
75137213	75137236	1	+	26627737	HCT116	viability after 15 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.7240695269601167	[368]	[73,153,149]	-6	hSpCas9	negative selection	2089641
75143232	75143255	1	+	26627737	HCT116	viability after 15 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.5018638487211798	[276]	[150,227,286]	5	hSpCas9	negative selection	2089642
75143923	75143946	1	-	26627737	HCT116	viability after 15 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.7839915179808274	[375]	[385,344,385]	6	hSpCas9	negative selection	2089643
75156981	75157004	1	-	26627737	HCT116	viability after 15 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	-0.4102625846215813	[215]	[72,64,138]	-4	hSpCas9	negative selection	2089644
75136656	75136679	1	+	26627737	HCT116	viability after 18 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-0.26959056101027845	[111]	[34,63,33]	-2	hSpCas9	negative selection	2171955
75137213	75137236	1	+	26627737	HCT116	viability after 18 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.3277373389713588	[368]	[148,131,404]	3	hSpCas9	negative selection	2171956
75143232	75143255	1	+	26627737	HCT116	viability after 18 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.434420234312471	[276]	[73,206,263]	4	hSpCas9	negative selection	2171957
75143923	75143946	1	-	26627737	HCT116	viability after 18 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.7791573213406311	[375]	[252,334,347]	6	hSpCas9	negative selection	2171958
75156981	75157004	1	-	26627737	HCT116	viability after 18 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	-0.11184781028569607	[215]	[98,111,76]	-1	hSpCas9	negative selection	2171959
75136609	75136632	1	+	24336569	HL60	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.595205541252441	[192]	[616]	5	hSpCas9	negative selection	2274691
75136626	75136649	1	+	24336569	HL60	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	-0.049808762262358336	[585]	[1197]	0	hSpCas9	negative selection	2274692
75136633	75136656	1	+	24336569	HL60	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	-0.9215444930001172	[835]	[933]	-7	hSpCas9	negative selection	2274693
75136643	75136666	1	-	24336569	HL60	viability	GCGAGTCCTCCCGGCCGCCAGGG	LHX8	ENSG00000162624	0.9327778219468824	[251]	[1017]	7	hSpCas9	negative selection	2274694
75136648	75136671	1	+	24336569	HL60	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.8578910777201085	[697]	[814]	-7	hSpCas9	negative selection	2274695
75136654	75136677	1	+	24336569	HL60	viability	GGGAGGACTCGCAAAGGCGCCGG	LHX8	ENSG00000162624	0.6863021930326633	[569]	[1940]	6	hSpCas9	negative selection	2274696
75137123	75137146	1	+	24336569	HL60	viability	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	-0.6834536129107049	[553]	[729]	-6	hSpCas9	negative selection	2274697
75137170	75137193	1	-	24336569	HL60	viability	GGAGCCCGAGGCCATGGACCGGG	LHX8	ENSG00000162624	-0.28533643399454633	[902]	[1567]	-3	hSpCas9	negative selection	2274698
75137176	75137199	1	-	24336569	HL60	viability	GCAGCCGGAGCCCGAGGCCATGG	LHX8	ENSG00000162624	-0.15665159702311549	[511]	[971]	-1	hSpCas9	negative selection	2274699
75137182	75137205	1	-	24336569	HL60	viability	AGGAGGGCAGCCGGAGCCCGAGG	LHX8	ENSG00000162624	-0.13273277093940644	[400]	[773]	-1	hSpCas9	negative selection	2274700
75136609	75136632	1	+	24336569	KBM7	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.7280065198330052	[483]	[796]	-5	hSpCas9	negative selection	2341868
75136626	75136649	1	+	24336569	KBM7	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.255995267605735	[388]	[1266]	2	hSpCas9	negative selection	2341869
75136633	75136656	1	+	24336569	KBM7	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.4338719415049774	[430]	[1587]	4	hSpCas9	negative selection	2341870
75136643	75136666	1	-	24336569	KBM7	viability	GCGAGTCCTCCCGGCCGCCAGGG	LHX8	ENSG00000162624	-0.2018866874886055	[271]	[644]	-2	hSpCas9	negative selection	2341871
75136648	75136671	1	+	24336569	KBM7	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.7481770153391597	[427]	[694]	-5	hSpCas9	negative selection	2341872
75136654	75136677	1	+	24336569	KBM7	viability	GGGAGGACTCGCAAAGGCGCCGG	LHX8	ENSG00000162624	0.08639937545346876	[719]	[2084]	0	hSpCas9	negative selection	2341873
75137123	75137146	1	+	24336569	KBM7	viability	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.021351310725163275	[288]	[799]	0	hSpCas9	negative selection	2341874
75137170	75137193	1	-	24336569	KBM7	viability	GGAGCCCGAGGCCATGGACCGGG	LHX8	ENSG00000162624	-0.7396220494528227	[853]	[1394]	-5	hSpCas9	negative selection	2341875
75137176	75137199	1	-	24336569	KBM7	viability	GCAGCCGGAGCCCGAGGCCATGG	LHX8	ENSG00000162624	0.14725354819633482	[436]	[1319]	1	hSpCas9	negative selection	2341876
75137182	75137205	1	-	24336569	KBM7	viability	AGGAGGGCAGCCGGAGCCCGAGG	LHX8	ENSG00000162624	-0.18114621425322397	[211]	[509]	-1	hSpCas9	negative selection	2341877
75134698	75134721	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGGTGAGCGAGCCGACGCCTGG	LHX8	ENSG00000162624	1.4602703935648118	[0,49]	[1,30]	5	dCas9-VP64	positive selection	2415828
75134726	75134749	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGGACACTGCGATTCAGCTGG	LHX8	ENSG00000162624	1.1059314388354506	[27,87]	[37,15]	4	dCas9-VP64	positive selection	2415829
75134710	75134733	1	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGCTGGTCTGGCCAGGCGTCGG	LHX8	ENSG00000162624	3.160681894390802	[8,37]	[3,92]	8	dCas9-VP64	positive selection	2415830
75153684	75153707	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGTGTGAGCCACCACGCCGGG	LHX8	ENSG00000162624	1.2080578617800355	[188,10]	[73,23]	5	dCas9-VP64	positive selection	2430218
75156290	75156313	1	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGAGTGCAGTGGTGCAATCTGAG	LHX8	ENSG00000162624	-0.951887234031858	[136,22]	[13,2]	-5	dCas9-VP64	positive selection	2476167
75134698	75134721	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGGTGAGCGAGCCGACGCCTGG	LHX8	ENSG00000162624	0.7405762111344856	[41,95]	[40,33]	5	dCas9-VP64	positive selection	2511083
75134726	75134749	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGGACACTGCGATTCAGCTGG	LHX8	ENSG00000162624	-0.31429209130409275	[37,56]	[14,8]	-3	dCas9-VP64	positive selection	2511084
75134710	75134733	1	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGCTGGTCTGGCCAGGCGTCGG	LHX8	ENSG00000162624	0.6882256977021157	[222,25]	[119,14]	5	dCas9-VP64	positive selection	2511085
75153684	75153707	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGTGTGAGCCACCACGCCGGG	LHX8	ENSG00000162624	1.0270683763310697	[166,152]	[69,140]	6	dCas9-VP64	positive selection	2525473
75156290	75156313	1	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGAGTGCAGTGGTGCAATCTGAG	LHX8	ENSG00000162624	-1.0138866146493042	[45,103]	[11,10]	-8	dCas9-VP64	positive selection	2571422
75137182	75137205	1	-	27260157	DLD1	viability	AGGAGGGCAGCCGGAGCCCGAGG	LHX8	ENSG00000162624	-0.461505126491872	[]	[]	-4	hSpCas9	negative selection	2573645
75134917	75134940	1	+	27260157	DLD1	viability	GAGATGAAGCCTCGAGCCTAAGG	LHX8	ENSG00000162624	0.257879932656679	[]	[]	4	hSpCas9	negative selection	2574708
75136633	75136656	1	+	27260157	DLD1	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	1.26616262882059	[]	[]	9	hSpCas9	negative selection	2575635
75137176	75137199	1	-	27260157	DLD1	viability	GCAGCCGGAGCCCGAGGCCATGG	LHX8	ENSG00000162624	0.218319644842881	[]	[]	3	hSpCas9	negative selection	2580691
75136654	75136677	1	+	27260157	DLD1	viability	GGGAGGACTCGCAAAGGCGCCGG	LHX8	ENSG00000162624	-0.207388400980264	[]	[]	-1	hSpCas9	negative selection	2583710
75137170	75137193	1	-	27260157	DLD1	viability	GGAGCCCGAGGCCATGGACCGGG	LHX8	ENSG00000162624	0.220070057878268	[]	[]	3	hSpCas9	negative selection	2585086
75136652	75136675	1	-	27260157	DLD1	viability	GGCGCCTTTGCGAGTCCTCCCGG	LHX8	ENSG00000162624	-0.111310370519086	[]	[]	-1	hSpCas9	negative selection	2585644
75136648	75136671	1	+	27260157	DLD1	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.669054296259482	[]	[]	8	hSpCas9	negative selection	2587667
75134926	75134949	1	-	27260157	DLD1	viability	CTGAGAGCGCCTTAGGCTCGAGG	LHX8	ENSG00000162624	0.00619526393344942	[]	[]	0	hSpCas9	negative selection	2605169
75134880	75134903	1	+	27260157	DLD1	viability	AGCTCACTTAACCTGAGACATGG	LHX8	ENSG00000162624	-0.265053135816495	[]	[]	-2	hSpCas9	negative selection	2606396
75136673	75136696	1	-	27260157	DLD1	viability	ACTCACCAGTCCCTCTTCCCCGG	LHX8	ENSG00000162624	-0.816956688935381	[]	[]	-6	hSpCas9	negative selection	2615691
75137123	75137146	1	+	27260157	DLD1	viability	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.251688845339495	[]	[]	4	hSpCas9	negative selection	2616198
75136626	75136649	1	+	27260157	DLD1	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.48397321449233	[]	[]	8	hSpCas9	negative selection	2618712
75134927	75134950	1	+	27260157	DLD1	viability	CTCGAGCCTAAGGCGCTCTCAGG	LHX8	ENSG00000162624	-0.340429591292698	[]	[]	-3	hSpCas9	negative selection	2620728
75136609	75136632	1	+	27260157	DLD1	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.758550893425428	[]	[]	-5	hSpCas9	negative selection	2623246
75137191	75137214	1	-	27260157	DLD1	viability	ACACTTGCCAGGAGGGCAGCCGG	LHX8	ENSG00000162624	0.557104241868874	[]	[]	8	hSpCas9	negative selection	2646525
75136643	75136666	1	-	27260157	DLD1	viability	GCGAGTCCTCCCGGCCGCCAGGG	LHX8	ENSG00000162624	0.187632591266281	[]	[]	3	hSpCas9	negative selection	2646987
75137208	75137231	1	+	27260157	DLD1	viability	AAGTGTGTGTGCAACAGTTGCGG	LHX8	ENSG00000162624	0.177627731793247	[]	[]	3	hSpCas9	negative selection	2648971
75137182	75137205	1	-	27260157	HT1080	viability	AGGAGGGCAGCCGGAGCCCGAGG	LHX8	ENSG00000162624	1.03389020657907	[]	[]	8	hSpCas9	negative selection	2649775
75134917	75134940	1	+	27260157	HT1080	viability	GAGATGAAGCCTCGAGCCTAAGG	LHX8	ENSG00000162624	1.62466498117318	[]	[]	9	hSpCas9	negative selection	2650838
75136633	75136656	1	+	27260157	HT1080	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.863849099588816	[]	[]	7	hSpCas9	negative selection	2651765
75137176	75137199	1	-	27260157	HT1080	viability	GCAGCCGGAGCCCGAGGCCATGG	LHX8	ENSG00000162624	1.73942848699664	[]	[]	9	hSpCas9	negative selection	2656821
75136654	75136677	1	+	27260157	HT1080	viability	GGGAGGACTCGCAAAGGCGCCGG	LHX8	ENSG00000162624	-0.722169265689493	[]	[]	-8	hSpCas9	negative selection	2659840
75137170	75137193	1	-	27260157	HT1080	viability	GGAGCCCGAGGCCATGGACCGGG	LHX8	ENSG00000162624	-0.303431725252049	[]	[]	-7	hSpCas9	negative selection	2661216
75136652	75136675	1	-	27260157	HT1080	viability	GGCGCCTTTGCGAGTCCTCCCGG	LHX8	ENSG00000162624	1.27707425113095	[]	[]	9	hSpCas9	negative selection	2661774
75136648	75136671	1	+	27260157	HT1080	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.175815407479825	[]	[]	1	hSpCas9	negative selection	2663797
75134926	75134949	1	-	27260157	HT1080	viability	CTGAGAGCGCCTTAGGCTCGAGG	LHX8	ENSG00000162624	-0.055141242946069	[]	[]	0	hSpCas9	negative selection	2681299
75134880	75134903	1	+	27260157	HT1080	viability	AGCTCACTTAACCTGAGACATGG	LHX8	ENSG00000162624	0.237356967569094	[]	[]	2	hSpCas9	negative selection	2682526
75136673	75136696	1	-	27260157	HT1080	viability	ACTCACCAGTCCCTCTTCCCCGG	LHX8	ENSG00000162624	-0.565447115193417	[]	[]	-7	hSpCas9	negative selection	2691821
75137123	75137146	1	+	27260157	HT1080	viability	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.147564520635428	[]	[]	1	hSpCas9	negative selection	2692328
75136626	75136649	1	+	27260157	HT1080	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.3407506020144	[]	[]	9	hSpCas9	negative selection	2694842
75134927	75134950	1	+	27260157	HT1080	viability	CTCGAGCCTAAGGCGCTCTCAGG	LHX8	ENSG00000162624	-0.0367257352017598	[]	[]	0	hSpCas9	negative selection	2696858
75136609	75136632	1	+	27260157	HT1080	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.610669696121434	[]	[]	-8	hSpCas9	negative selection	2699376
75137191	75137214	1	-	27260157	HT1080	viability	ACACTTGCCAGGAGGGCAGCCGG	LHX8	ENSG00000162624	0.517683597869595	[]	[]	4	hSpCas9	negative selection	2722655
75136643	75136666	1	-	27260157	HT1080	viability	GCGAGTCCTCCCGGCCGCCAGGG	LHX8	ENSG00000162624	0.943610193492218	[]	[]	7	hSpCas9	negative selection	2723117
75137208	75137231	1	+	27260157	HT1080	viability	AAGTGTGTGTGCAACAGTTGCGG	LHX8	ENSG00000162624	-0.737028067694869	[]	[]	-8	hSpCas9	negative selection	2725101
75137182	75137205	1	-	27260157	MKN45	viability	AGGAGGGCAGCCGGAGCCCGAGG	LHX8	ENSG00000162624	0.750344661848293	[]	[]	7	hSpCas9	negative selection	2725905
75134917	75134940	1	+	27260157	MKN45	viability	GAGATGAAGCCTCGAGCCTAAGG	LHX8	ENSG00000162624	1.3493895015019	[]	[]	9	hSpCas9	negative selection	2726968
75136633	75136656	1	+	27260157	MKN45	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	1.40974666322315	[]	[]	9	hSpCas9	negative selection	2727895
75137176	75137199	1	-	27260157	MKN45	viability	GCAGCCGGAGCCCGAGGCCATGG	LHX8	ENSG00000162624	1.36692747350518	[]	[]	9	hSpCas9	negative selection	2732951
75136654	75136677	1	+	27260157	MKN45	viability	GGGAGGACTCGCAAAGGCGCCGG	LHX8	ENSG00000162624	0.098910571679432	[]	[]	0	hSpCas9	negative selection	2735970
75137170	75137193	1	-	27260157	MKN45	viability	GGAGCCCGAGGCCATGGACCGGG	LHX8	ENSG00000162624	0.0961731522861194	[]	[]	0	hSpCas9	negative selection	2737346
75136652	75136675	1	-	27260157	MKN45	viability	GGCGCCTTTGCGAGTCCTCCCGG	LHX8	ENSG00000162624	-0.279299015913245	[]	[]	-1	hSpCas9	negative selection	2737904
75136648	75136671	1	+	27260157	MKN45	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.741094742882402	[]	[]	7	hSpCas9	negative selection	2739927
75134926	75134949	1	-	27260157	MKN45	viability	CTGAGAGCGCCTTAGGCTCGAGG	LHX8	ENSG00000162624	-0.117933250870565	[]	[]	0	hSpCas9	negative selection	2757429
75134880	75134903	1	+	27260157	MKN45	viability	AGCTCACTTAACCTGAGACATGG	LHX8	ENSG00000162624	0.261964355528058	[]	[]	5	hSpCas9	negative selection	2758656
75136673	75136696	1	-	27260157	MKN45	viability	ACTCACCAGTCCCTCTTCCCCGG	LHX8	ENSG00000162624	-2.23399694997967	[]	[]	-9	hSpCas9	negative selection	2767951
75137123	75137146	1	+	27260157	MKN45	viability	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.371557347251157	[]	[]	6	hSpCas9	negative selection	2768458
75136626	75136649	1	+	27260157	MKN45	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.04399166089055	[]	[]	8	hSpCas9	negative selection	2770972
75134927	75134950	1	+	27260157	MKN45	viability	CTCGAGCCTAAGGCGCTCTCAGG	LHX8	ENSG00000162624	0.192011240182435	[]	[]	5	hSpCas9	negative selection	2772988
75136609	75136632	1	+	27260157	MKN45	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.589585669971307	[]	[]	7	hSpCas9	negative selection	2775506
75137191	75137214	1	-	27260157	MKN45	viability	ACACTTGCCAGGAGGGCAGCCGG	LHX8	ENSG00000162624	0.42306771862235	[]	[]	6	hSpCas9	negative selection	2798785
75136643	75136666	1	-	27260157	MKN45	viability	GCGAGTCCTCCCGGCCGCCAGGG	LHX8	ENSG00000162624	0.280992836227987	[]	[]	5	hSpCas9	negative selection	2799247
75137208	75137231	1	+	27260157	MKN45	viability	AAGTGTGTGTGCAACAGTTGCGG	LHX8	ENSG00000162624	0.168005413423609	[]	[]	5	hSpCas9	negative selection	2801231
75137182	75137205	1	-	27260157	RKO	viability	AGGAGGGCAGCCGGAGCCCGAGG	LHX8	ENSG00000162624	0.00458258092934104	[]	[]	0	hSpCas9	negative selection	2802035
75134917	75134940	1	+	27260157	RKO	viability	GAGATGAAGCCTCGAGCCTAAGG	LHX8	ENSG00000162624	1.18990083732551	[]	[]	9	hSpCas9	negative selection	2803098
75136633	75136656	1	+	27260157	RKO	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.973757712913933	[]	[]	8	hSpCas9	negative selection	2804025
75137176	75137199	1	-	27260157	RKO	viability	GCAGCCGGAGCCCGAGGCCATGG	LHX8	ENSG00000162624	1.14139231002968	[]	[]	9	hSpCas9	negative selection	2809081
75136654	75136677	1	+	27260157	RKO	viability	GGGAGGACTCGCAAAGGCGCCGG	LHX8	ENSG00000162624	-0.276394396083995	[]	[]	-1	hSpCas9	negative selection	2812100
75137170	75137193	1	-	27260157	RKO	viability	GGAGCCCGAGGCCATGGACCGGG	LHX8	ENSG00000162624	-1.01975871432212	[]	[]	-8	hSpCas9	negative selection	2813476
75136652	75136675	1	-	27260157	RKO	viability	GGCGCCTTTGCGAGTCCTCCCGG	LHX8	ENSG00000162624	-0.230867290255076	[]	[]	-1	hSpCas9	negative selection	2814034
75136648	75136671	1	+	27260157	RKO	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	1.30702905624327	[]	[]	9	hSpCas9	negative selection	2816057
75134926	75134949	1	-	27260157	RKO	viability	CTGAGAGCGCCTTAGGCTCGAGG	LHX8	ENSG00000162624	-0.115647636982618	[]	[]	0	hSpCas9	negative selection	2833559
75134880	75134903	1	+	27260157	RKO	viability	AGCTCACTTAACCTGAGACATGG	LHX8	ENSG00000162624	0.12678648193392	[]	[]	0	hSpCas9	negative selection	2834786
75136673	75136696	1	-	27260157	RKO	viability	ACTCACCAGTCCCTCTTCCCCGG	LHX8	ENSG00000162624	-0.0457018976453189	[]	[]	0	hSpCas9	negative selection	2844081
75137123	75137146	1	+	27260157	RKO	viability	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.0935928632804423	[]	[]	0	hSpCas9	negative selection	2844588
75136626	75136649	1	+	27260157	RKO	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.661624918162592	[]	[]	3	hSpCas9	negative selection	2847102
75134927	75134950	1	+	27260157	RKO	viability	CTCGAGCCTAAGGCGCTCTCAGG	LHX8	ENSG00000162624	0.586676535813684	[]	[]	3	hSpCas9	negative selection	2849118
75136609	75136632	1	+	27260157	RKO	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.58662943400515	[]	[]	-7	hSpCas9	negative selection	2851636
75137191	75137214	1	-	27260157	RKO	viability	ACACTTGCCAGGAGGGCAGCCGG	LHX8	ENSG00000162624	0.541867080938967	[]	[]	3	hSpCas9	negative selection	2874915
75136643	75136666	1	-	27260157	RKO	viability	GCGAGTCCTCCCGGCCGCCAGGG	LHX8	ENSG00000162624	0.754899288506782	[]	[]	8	hSpCas9	negative selection	2875377
75137208	75137231	1	+	27260157	RKO	viability	AAGTGTGTGTGCAACAGTTGCGG	LHX8	ENSG00000162624	0.237099324220035	[]	[]	1	hSpCas9	negative selection	2877361
75137182	75137205	1	-	27260157	SF268	viability	AGGAGGGCAGCCGGAGCCCGAGG	LHX8	ENSG00000162624	0.194697377216547	[]	[]	3	hSpCas9	negative selection	2878165
75134917	75134940	1	+	27260157	SF268	viability	GAGATGAAGCCTCGAGCCTAAGG	LHX8	ENSG00000162624	0.929927456838306	[]	[]	9	hSpCas9	negative selection	2879228
75136633	75136656	1	+	27260157	SF268	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	1.44964952905465	[]	[]	9	hSpCas9	negative selection	2880155
75137176	75137199	1	-	27260157	SF268	viability	GCAGCCGGAGCCCGAGGCCATGG	LHX8	ENSG00000162624	1.60751800793108	[]	[]	9	hSpCas9	negative selection	2885211
75136654	75136677	1	+	27260157	SF268	viability	GGGAGGACTCGCAAAGGCGCCGG	LHX8	ENSG00000162624	-1.00766049654768	[]	[]	-7	hSpCas9	negative selection	2888230
75137170	75137193	1	-	27260157	SF268	viability	GGAGCCCGAGGCCATGGACCGGG	LHX8	ENSG00000162624	-0.562871898346619	[]	[]	-4	hSpCas9	negative selection	2889606
75136652	75136675	1	-	27260157	SF268	viability	GGCGCCTTTGCGAGTCCTCCCGG	LHX8	ENSG00000162624	-1.43950522828314	[]	[]	-8	hSpCas9	negative selection	2890164
75136648	75136671	1	+	27260157	SF268	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	1.10875757376143	[]	[]	9	hSpCas9	negative selection	2892187
75134926	75134949	1	-	27260157	SF268	viability	CTGAGAGCGCCTTAGGCTCGAGG	LHX8	ENSG00000162624	0.37460278770358	[]	[]	4	hSpCas9	negative selection	2909689
75134880	75134903	1	+	27260157	SF268	viability	AGCTCACTTAACCTGAGACATGG	LHX8	ENSG00000162624	0.00201147014993172	[]	[]	0	hSpCas9	negative selection	2910916
75136673	75136696	1	-	27260157	SF268	viability	ACTCACCAGTCCCTCTTCCCCGG	LHX8	ENSG00000162624	-1.40856046616886	[]	[]	-8	hSpCas9	negative selection	2920211
75137123	75137146	1	+	27260157	SF268	viability	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	-0.501174419659647	[]	[]	-4	hSpCas9	negative selection	2920718
75136626	75136649	1	+	27260157	SF268	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.32448721342838	[]	[]	9	hSpCas9	negative selection	2923232
75134927	75134950	1	+	27260157	SF268	viability	CTCGAGCCTAAGGCGCTCTCAGG	LHX8	ENSG00000162624	-0.165785968329121	[]	[]	-1	hSpCas9	negative selection	2925248
75136609	75136632	1	+	27260157	SF268	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.374238254983682	[]	[]	-3	hSpCas9	negative selection	2927766
75137191	75137214	1	-	27260157	SF268	viability	ACACTTGCCAGGAGGGCAGCCGG	LHX8	ENSG00000162624	-0.0946778889216852	[]	[]	0	hSpCas9	negative selection	2951045
75136643	75136666	1	-	27260157	SF268	viability	GCGAGTCCTCCCGGCCGCCAGGG	LHX8	ENSG00000162624	0.00811569182352309	[]	[]	0	hSpCas9	negative selection	2951507
75137208	75137231	1	+	27260157	SF268	viability	AAGTGTGTGTGCAACAGTTGCGG	LHX8	ENSG00000162624	-1.07262362052353	[]	[]	-7	hSpCas9	negative selection	2953491
75143169	75143192	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ACTGGGTCCGGAGAGCCAAGGGG	LHX8	ENSG00000162624	0.5794970752973259	[2,2]	[4,3]	9	hSpCas9	positive selection	2999409
75143183	75143206	1	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CAAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	-0.21693300329331536	[5,4]	[5,2]	-3	hSpCas9	positive selection	2999410
75136657	75136680	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.22857105361359994	[3,3]	[3,3]	5	hSpCas9	positive selection	2999411
75137091	75137114	1	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTTCCTGCAGGTGAGCCCCGAGG	LHX8	ENSG00000162624	-0.6250723847429481	[2,2]	[2,0]	-7	hSpCas9	positive selection	2999412
75143169	75143192	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ACTGGGTCCGGAGAGCCAAGGGG	LHX8	ENSG00000162624	-0.3411915887485283	[2,2]	[2,0]	-5	hSpCas9	positive selection	3067267
75143183	75143206	1	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CAAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.004554746404447307	[5,5]	[4,2]	0	hSpCas9	positive selection	3067268
75136657	75136680	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-0.213173007932985	[3,3]	[3,1]	-3	hSpCas9	positive selection	3067269
75137091	75137114	1	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTTCCTGCAGGTGAGCCCCGAGG	LHX8	ENSG00000162624	-0.25178727425439124	[2,2]	[2,0]	-4	hSpCas9	positive selection	3067270
75137123	75137146		+	24336571	A375	resistance to PLX after 7 days	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.0557737844037276	[74,75]	[79,76]	2	hSpCas9	positive selection	3124627
75140993	75141016		-	24336571	A375	resistance to PLX after 7 days	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.014866023812327989	[17,14]	[15,15]	0	hSpCas9	positive selection	3124628
75136626	75136649		+	24336571	A375	resistance to PLX after 7 days	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	-0.26595666416755914	[6,6]	[4,6]	-7	hSpCas9	positive selection	3124629
75136602	75136625		+	24336571	A375	resistance to PLX after 7 days	GTGTCAGGGGCTCATGTCAGAGG	LHX8	ENSG00000162624	0.17640536863853973	[6,6]	[8,7]	5	hSpCas9	positive selection	3124630
75136644	75136667		-	24336571	A375	resistance to PLX after 7 days	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.40534349378667045	[5,5]	[7,7]	8	hSpCas9	positive selection	3124631
75137123	75137146		+	24336571	A375	resistance to PLX after 14 days	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.3310175997358744	[81,78]	[46,46]	3	hSpCas9	positive selection	3182420
75140993	75141016		-	24336571	A375	resistance to PLX after 14 days	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.16409646593198784	[12,18]	[7,7]	1	hSpCas9	positive selection	3182421
75136626	75136649		+	24336571	A375	resistance to PLX after 14 days	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	-0.07610916637198167	[7,10]	[4,1]	-1	hSpCas9	positive selection	3182422
75136602	75136625		+	24336571	A375	resistance to PLX after 14 days	GTGTCAGGGGCTCATGTCAGAGG	LHX8	ENSG00000162624	0.2296605363654908	[8,8]	[3,4]	2	hSpCas9	positive selection	3182423
75136644	75136667		-	24336571	A375	resistance to PLX after 14 days	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.19424630367864926	[8,5]	[3,2]	2	hSpCas9	positive selection	3182424
75137123	75137146		+	24336571	A375	viability after 7 days	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.5753343566776339	[52]	[74,75]	8	hSpCas9	negative selection	3240213
75140993	75141016		-	24336571	A375	viability after 7 days	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.4306789565124374	[12]	[17,14]	6	hSpCas9	negative selection	3240214
75136626	75136649		+	24336571	A375	viability after 7 days	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.6273583963815269	[4]	[6,6]	8	hSpCas9	negative selection	3240215
75136602	75136625		+	24336571	A375	viability after 7 days	GTGTCAGGGGCTCATGTCAGAGG	LHX8	ENSG00000162624	0.2291013430738772	[6]	[6,6]	3	hSpCas9	negative selection	3240216
75136644	75136667		-	24336571	A375	viability after 7 days	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	-0.2222526189998345	[6]	[5,5]	-3	hSpCas9	negative selection	3240217
75137123	75137146		+	24336571	A375	viability after 14 days	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.6797755785951654	[52]	[81,78]	8	hSpCas9	negative selection	3298006
75140993	75141016		-	24336571	A375	viability after 14 days	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.425955610210677	[12]	[12,18]	5	hSpCas9	negative selection	3298007
75136626	75136649		+	24336571	A375	viability after 14 days	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.9444992989593486	[4]	[7,10]	9	hSpCas9	negative selection	3298008
75136602	75136625		+	24336571	A375	viability after 14 days	GTGTCAGGGGCTCATGTCAGAGG	LHX8	ENSG00000162624	0.5327498319303929	[6]	[8,8]	6	hSpCas9	negative selection	3298009
75136644	75136667		-	24336571	A375	viability after 14 days	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.10915021540998238	[6]	[8,5]	1	hSpCas9	negative selection	3298010
75143125	75143148	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	1.107579091941153	[70,70]	[0,0]	5	hSpCas9	positive selection	3377135
75143280	75143303	1	-	27383988	293T	resistance to West Nile virus (flavivirus)	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	0.5849008694743394	[101,101]	[0,0]	3	hSpCas9	positive selection	3377136
75137240	75137263	1	+	27383988	293T	resistance to West Nile virus (flavivirus)	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.18051061439500407	[134,134]	[0,0]	1	hSpCas9	positive selection	3377137
75143168	75143191	1	+	26780180	HT29	viability (Avana library 4 designs)	ACTGGGTCCGGAGAGCCAAGGGG	LHX8	ENSG00000162624	2.12553511557978	[]	[]	7	hSpCas9	negative selection	3436956
75143183	75143206	1	-	26780180	HT29	viability (Avana library 4 designs)	CAAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	-0.179862492558815	[]	[]	-3	hSpCas9	negative selection	3436957
75136656	75136679	1	+	26780180	HT29	viability (Avana library 4 designs)	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	1.25156698083764	[]	[]	5	hSpCas9	negative selection	3436958
75137090	75137113	1	+	26780180	HT29	viability (Avana library 4 designs)	TTTCCTGCAGGTGAGCCCCGAGG	LHX8	ENSG00000162624	-0.297754147689116	[]	[]	-5	hSpCas9	negative selection	3436959
75137090	75137113	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTTCCTGCAGGTGAGCCCCGAGG	LHX8	ENSG00000162624	3.15136066308546	[]	[]	5	hSpCas9	negative selection	3525433
75136656	75136679	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	3.96596918576359	[]	[]	6	hSpCas9	negative selection	3525434
75143168	75143191	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACTGGGTCCGGAGAGCCAAGGGG	LHX8	ENSG00000162624	2.46261519532719	[]	[]	3	hSpCas9	negative selection	3525435
75143183	75143206	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	CAAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	2.59568088609617	[]	[]	4	hSpCas9	negative selection	3525436
75136637	75136660	1	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACAGCCCTGGCGGCCGGGAGG	LHX8	ENSG00000162624	5.31488365025907	[]	[]	8	hSpCas9	negative selection	3525437
75137199	75137222	1	-	26780180	A375	viability (Avana lentiCRISPRv2)	TTGCACACACACTTGCCAGGAGG	LHX8	ENSG00000162624	2.91587563433707	[]	[]	4	hSpCas9	negative selection	3525438
75137090	75137113	1	+	26780180	A375	viability (Avana lentiGuide)	TTTCCTGCAGGTGAGCCCCGAGG	LHX8	ENSG00000162624	-3.48337046664217	[]	[]	-6	hSpCas9	negative selection	3634092
75136656	75136679	1	+	26780180	A375	viability (Avana lentiGuide)	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	4.30528124509082	[]	[]	4	hSpCas9	negative selection	3634093
75143168	75143191	1	+	26780180	A375	viability (Avana lentiGuide)	ACTGGGTCCGGAGAGCCAAGGGG	LHX8	ENSG00000162624	15.6335589926595	[]	[]	8	hSpCas9	negative selection	3634094
75143183	75143206	1	-	26780180	A375	viability (Avana lentiGuide)	CAAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	-1.08412950645834	[]	[]	-2	hSpCas9	negative selection	3634095
75136637	75136660	1	+	26780180	A375	viability (Avana lentiGuide)	CTACAGCCCTGGCGGCCGGGAGG	LHX8	ENSG00000162624	2.18980381340179	[]	[]	2	hSpCas9	negative selection	3634096
75137199	75137222	1	-	26780180	A375	viability (Avana lentiGuide)	TTGCACACACACTTGCCAGGAGG	LHX8	ENSG00000162624	-3.40227834820894	[]	[]	-6	hSpCas9	negative selection	3634097
75137090	75137113	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTTCCTGCAGGTGAGCCCCGAGG	LHX8	ENSG00000162624	0.2052394104195073	[4]	[5,4]	6	hSpCas9	positive selection	3742751
75136656	75136679	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.2007537366251179	[5]	[6,5]	5	hSpCas9	positive selection	3742752
75143168	75143191	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACTGGGTCCGGAGAGCCAAGGGG	LHX8	ENSG00000162624	0.12720608982469306	[4]	[4,4]	3	hSpCas9	positive selection	3742753
75143183	75143206	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CAAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.17984883071068403	[5]	[6,6]	5	hSpCas9	positive selection	3742754
75136637	75136660	1	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACAGCCCTGGCGGCCGGGAGG	LHX8	ENSG00000162624	0.32560641710064525	[4]	[4,6]	8	hSpCas9	positive selection	3742755
75137199	75137222	1	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTGCACACACACTTGCCAGGAGG	LHX8	ENSG00000162624	0.0923787793678575	[4]	[4,4]	2	hSpCas9	positive selection	3742756
75137090	75137113	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTTCCTGCAGGTGAGCCCCGAGG	LHX8	ENSG00000162624	0.1616881240878435	[4]	[4,3]	4	hSpCas9	positive selection	3851358
75136656	75136679	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	0.066541853559832	[6]	[6,4]	1	hSpCas9	positive selection	3851359
75143168	75143191	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACTGGGTCCGGAGAGCCAAGGGG	LHX8	ENSG00000162624	-0.8588606880986497	[4]	[3,0]	-8	hSpCas9	positive selection	3851360
75143183	75143206	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CAAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.3139749231169834	[6]	[7,7]	8	hSpCas9	positive selection	3851361
75136637	75136660	1	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACAGCCCTGGCGGCCGGGAGG	LHX8	ENSG00000162624	-0.35949411874517345	[4]	[4,1]	-5	hSpCas9	positive selection	3851362
75137199	75137222	1	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTGCACACACACTTGCCAGGAGG	LHX8	ENSG00000162624	0.049468221174469744	[5]	[4,5]	1	hSpCas9	positive selection	3851363
75143280	75143303	1	-	26780180	A375	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	1.09589818782907	[]	[]	5	hSpCas9	negative selection	3957024
75136633	75136656	1	+	26780180	A375	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.814092186289538	[]	[]	3	hSpCas9	negative selection	3957025
75137240	75137263	1	+	26780180	A375	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.726482197012951	[]	[]	2	hSpCas9	negative selection	3957026
75140993	75141016	1	-	26780180	A375	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	1.45029312610606	[]	[]	8	hSpCas9	negative selection	3957027
75143125	75143148	1	+	26780180	A375	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	1.46682678144005	[]	[]	8	hSpCas9	negative selection	3957028
75136644	75136667	1	-	26780180	A375	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	1.05515162136663	[]	[]	5	hSpCas9	negative selection	3957029
75143280	75143303	1	-	26780180	HT29	viability (GeCKOv2 library)	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	1.93308028926883	[]	[]	9	hSpCas9	negative selection	4064990
75136633	75136656	1	+	26780180	HT29	viability (GeCKOv2 library)	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.326121540341785	[]	[]	0	hSpCas9	negative selection	4064991
75137240	75137263	1	+	26780180	HT29	viability (GeCKOv2 library)	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	1.02609605935268	[]	[]	5	hSpCas9	negative selection	4064992
75140993	75141016	1	-	26780180	HT29	viability (GeCKOv2 library)	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	1.89876945720446	[]	[]	9	hSpCas9	negative selection	4064993
75143125	75143148	1	+	26780180	HT29	viability (GeCKOv2 library)	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	1.54560272717564	[]	[]	7	hSpCas9	negative selection	4064994
75136644	75136667	1	-	26780180	HT29	viability (GeCKOv2 library)	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.34776399431217	[]	[]	1	hSpCas9	negative selection	4064995
75137123	75137146	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	0.4247427752626094	[6]	[5,5]	8	hSpCas9	positive selection	4148693
75140993	75141016	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.13659900165070862	[4]	[2,2]	3	hSpCas9	positive selection	4148694
75136626	75136649	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	-0.2801203440580403	[3]	[1,1]	-6	hSpCas9	positive selection	4148695
75136602	75136625	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTGTCAGGGGCTCATGTCAGAGG	LHX8	ENSG00000162624	-0.3261800654254886	[3]	[0,2]	-7	hSpCas9	positive selection	4148696
75136644	75136667	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.14219031646745733	[2]	[1,1]	3	hSpCas9	positive selection	4148697
75137123	75137146	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGAGGACTCGTGCTCCTCCTCGG	LHX8	ENSG00000162624	1.1021123847123109	[5]	[6,6,1,5]	8	hSpCas9	positive selection	4212715
75140993	75141016	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.05943141962541876	[2]	[1,1,0,0]	-1	hSpCas9	positive selection	4212716
75136626	75136649	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.0220532291536168	[0]	[0,0,0,0]	7	hSpCas9	positive selection	4212717
75136602	75136625	1	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTGTCAGGGGCTCATGTCAGAGG	LHX8	ENSG00000162624	-0.10188701813088197	[1]	[0,0,0,0]	-1	hSpCas9	positive selection	4212718
75136644	75136667	1	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.711418317576008	[3]	[0,1,0,3]	4	hSpCas9	positive selection	4212719
75136633	75136656	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.29580792707003933	[1]	[2,1]	6	hSpCas9	positive selection	4280135
75136644	75136667	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.17224959866619885	[2]	[2,2]	3	hSpCas9	positive selection	4280136
75140993	75141016	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.4836574452791938	[3]	[2,0]	-8	hSpCas9	positive selection	4280137
75143125	75143148	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.1421051235041576	[2]	[1,1]	-3	hSpCas9	positive selection	4344391
75143280	75143303	1	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.2875529780982443	[2]	[1,0]	-5	hSpCas9	positive selection	4344392
75137240	75137263	1	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.13392148399320036	[3]	[2,1]	-3	hSpCas9	positive selection	4344393
75140993	75141015	1	-	27760321	OCIAML3	viability	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.7228728900650817	[845,660]	[975,952]	8	hSpCas9	negative selection	4414402
75143105	75143127	1	+	27760321	OCIAML3	viability	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-2.4300102531455616	[13,7]	[1,0]	-9	hSpCas9	negative selection	4414403
75143151	75143173	1	+	27760321	OCIAML3	viability	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	-0.08382599034703886	[282,216]	[130,250]	-1	hSpCas9	negative selection	4414404
75143183	75143205	1	-	27760321	OCIAML3	viability	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.5158936314620926	[2765,2348]	[2502,3302]	6	hSpCas9	negative selection	4414405
75143233	75143255	1	+	27760321	OCIAML3	viability	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.4099640757196496	[299,241]	[230,343]	5	hSpCas9	negative selection	4414406
75140993	75141015	1	-	27760321	OCIAML2	viability	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.2910857040113676	[845,660]	[650,858]	4	hSpCas9	negative selection	4497865
75143105	75143127	1	+	27760321	OCIAML2	viability	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-1.927503743868118	[13,7]	[0,3]	-9	hSpCas9	negative selection	4497866
75143151	75143173	1	+	27760321	OCIAML2	viability	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	-0.02263349494062028	[282,216]	[194,200]	0	hSpCas9	negative selection	4497867
75143183	75143205	1	-	27760321	OCIAML2	viability	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.25714995104552285	[2765,2348]	[1897,3209]	3	hSpCas9	negative selection	4497868
75143233	75143255	1	+	27760321	OCIAML2	viability	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.5940429907567459	[299,241]	[272,402]	7	hSpCas9	negative selection	4497869
75140993	75141015	1	-	27760321	MV411	viability	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.7178381455861546	[845,660]	[637,1073]	5	hSpCas9	negative selection	4581328
75143105	75143127	1	+	27760321	MV411	viability	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-0.9068084526089102	[13,7]	[0,7]	-6	hSpCas9	negative selection	4581329
75143151	75143173	1	+	27760321	MV411	viability	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	-0.025739859051198244	[282,216]	[201,98]	0	hSpCas9	negative selection	4581330
75143183	75143205	1	-	27760321	MV411	viability	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.7113356021635053	[2765,2348]	[2609,2969]	5	hSpCas9	negative selection	4581331
75143233	75143255	1	+	27760321	MV411	viability	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	1.0523214928575815	[299,241]	[170,665]	7	hSpCas9	negative selection	4581332
75140993	75141015	1	-	27760321	HL60	viability	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.4150938393462381	[845,660]	[819,809]	5	hSpCas9	negative selection	4664791
75143105	75143127	1	+	27760321	HL60	viability	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-1.1718405586930194	[13,7]	[0,6]	-8	hSpCas9	negative selection	4664792
75143151	75143173	1	+	27760321	HL60	viability	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	0.5078906241287412	[282,216]	[327,245]	6	hSpCas9	negative selection	4664793
75143183	75143205	1	-	27760321	HL60	viability	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.1458099964571966	[2765,2348]	[2053,2567]	1	hSpCas9	negative selection	4664794
75143233	75143255	1	+	27760321	HL60	viability	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	1.2583932718671855	[299,241]	[399,660]	9	hSpCas9	negative selection	4664795
75140993	75141015	1	-	27760321	HT1080	viability	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.9250572610775463	[660,515]	[342,556]	5	hSpCas9	negative selection	4748254
75143105	75143127	1	+	27760321	HT1080	viability	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-1.4759873735460216	[7,5]	[0,0]	-5	hSpCas9	negative selection	4748255
75143151	75143173	1	+	27760321	HT1080	viability	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	2.166761388514434	[216,169]	[497,179]	9	hSpCas9	negative selection	4748256
75143183	75143205	1	-	27760321	HT1080	viability	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	1.2473154605712065	[2348,1832]	[1576,2415]	6	hSpCas9	negative selection	4748257
75143233	75143255	1	+	27760321	HT1080	viability	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	1.4470283543828548	[241,188]	[203,266]	7	hSpCas9	negative selection	4748258
75140993	75141015	1	-	27760321	HT29	viability after 7 days	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.6843149427703596	[660,515]	[1019,1318,1276]	9	hSpCas9	negative selection	4831717
75143105	75143127	1	+	27760321	HT29	viability after 7 days	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-3.165647627095286	[7,5]	[0,0,0]	-9	hSpCas9	negative selection	4831718
75143151	75143173	1	+	27760321	HT29	viability after 7 days	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	0.4040079106489355	[216,169]	[279,329,368]	6	hSpCas9	negative selection	4831719
75143183	75143205	1	-	27760321	HT29	viability after 7 days	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.07842201443666408	[2348,1832]	[3033,2619,2883]	1	hSpCas9	negative selection	4831720
75143233	75143255	1	+	27760321	HT29	viability after 7 days	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	1.0027947061329807	[241,188]	[741,535,417]	9	hSpCas9	negative selection	4831721
75140993	75141015	1	-	27760321	HT29	viability after 25 days	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.555206183363022	[660,515]	[943,1102,910]	6	hSpCas9	negative selection	4915180
75143105	75143127	1	+	27760321	HT29	viability after 25 days	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-0.6617999981602205	[7,5]	[1,10,1]	-5	hSpCas9	negative selection	4915181
75143151	75143173	1	+	27760321	HT29	viability after 25 days	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	0.6456009480209701	[216,169]	[341,304,395]	7	hSpCas9	negative selection	4915182
75143183	75143205	1	-	27760321	HT29	viability after 25 days	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.0896208228258728	[2348,1832]	[2173,2867,2612]	0	hSpCas9	negative selection	4915183
75143233	75143255	1	+	27760321	HT29	viability after 25 days	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	1.1095209481284019	[241,188]	[401,552,659]	9	hSpCas9	negative selection	4915184
75140993	75141015	1	-	27760321	HT29	viability after 22 days	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.6814742181892002	[660,515]	[1003,1250,1019]	7	hSpCas9	negative selection	4998643
75143105	75143127	1	+	27760321	HT29	viability after 22 days	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-0.7919393829348431	[7,5]	[4,1,6]	-6	hSpCas9	negative selection	4998644
75143151	75143173	1	+	27760321	HT29	viability after 22 days	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	0.6645256500767653	[216,169]	[389,420,250]	7	hSpCas9	negative selection	4998645
75143183	75143205	1	-	27760321	HT29	viability after 22 days	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.3323674133360268	[2348,1832]	[2909,3085,3138]	3	hSpCas9	negative selection	4998646
75143233	75143255	1	+	27760321	HT29	viability after 22 days	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.9250372648070647	[241,188]	[425,562,430]	9	hSpCas9	negative selection	4998647
75140993	75141015	1	-	27760321	HT29	viability after 19 days	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.51365115905301	[660,515]	[1214,1009,693]	5	hSpCas9	negative selection	5082106
75143105	75143127	1	+	27760321	HT29	viability after 19 days	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	1.1101226164870326	[7,5]	[30,0,20]	9	hSpCas9	negative selection	5082107
75143151	75143173	1	+	27760321	HT29	viability after 19 days	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	0.9810976255653706	[216,169]	[229,544,510]	8	hSpCas9	negative selection	5082108
75143183	75143205	1	-	27760321	HT29	viability after 19 days	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.23426878752618707	[2348,1832]	[2622,2651,3129]	2	hSpCas9	negative selection	5082109
75143233	75143255	1	+	27760321	HT29	viability after 19 days	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.971190460823884	[241,188]	[522,381,545]	8	hSpCas9	negative selection	5082110
75140993	75141015	1	-	27760321	HT29	viability after 16 days	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.7630777713172325	[660,515]	[1217,1062,1081]	8	hSpCas9	negative selection	5165569
75143105	75143127	1	+	27760321	HT29	viability after 16 days	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	2.9527481182820905	[7,5]	[9,162,0]	9	hSpCas9	negative selection	5165570
75143151	75143173	1	+	27760321	HT29	viability after 16 days	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	0.3143823272473242	[216,169]	[204,294,300]	3	hSpCas9	negative selection	5165571
75143183	75143205	1	-	27760321	HT29	viability after 16 days	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.22195992052944646	[2348,1832]	[3020,2675,2516]	2	hSpCas9	negative selection	5165572
75143233	75143255	1	+	27760321	HT29	viability after 16 days	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.7615918466616145	[241,188]	[482,303,448]	8	hSpCas9	negative selection	5165573
75140993	75141015	1	-	27760321	HT29	viability after 13 days	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.5874182384528963	[660,515]	[1281,977,828]	7	hSpCas9	negative selection	5249032
75143105	75143127	1	+	27760321	HT29	viability after 13 days	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	0.581368707971949	[7,5]	[34,0,0]	7	hSpCas9	negative selection	5249033
75143151	75143173	1	+	27760321	HT29	viability after 13 days	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	-0.22996229096483345	[216,169]	[122,268,182]	-3	hSpCas9	negative selection	5249034
75143183	75143205	1	-	27760321	HT29	viability after 13 days	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.23550038750456137	[2348,1832]	[2978,3041,2563]	3	hSpCas9	negative selection	5249035
75143233	75143255	1	+	27760321	HT29	viability after 13 days	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.682704239459974	[241,188]	[373,378,447]	8	hSpCas9	negative selection	5249036
75140993	75141015	1	-	27760321	HT29	viability after 10 days	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.4674923160184927	[660,515]	[1147,1000,900]	6	hSpCas9	negative selection	5332495
75143105	75143127	1	+	27760321	HT29	viability after 10 days	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	-0.4313592460080997	[7,5]	[0,0,16]	-5	hSpCas9	negative selection	5332496
75143151	75143173	1	+	27760321	HT29	viability after 10 days	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	0.08840078686979524	[216,169]	[290,146,327]	1	hSpCas9	negative selection	5332497
75143183	75143205	1	-	27760321	HT29	viability after 10 days	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	0.16411542894753728	[2348,1832]	[3536,3087,2171]	2	hSpCas9	negative selection	5332498
75143233	75143255	1	+	27760321	HT29	viability after 10 days	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.5761888683807245	[241,188]	[326,545,335]	7	hSpCas9	negative selection	5332499
75140993	75141015	1	-	27760321	MOLM13	viability	ACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.4994546833092596	[845,660]	[456,715]	3	hSpCas9	negative selection	5415958
75143105	75143127	1	+	27760321	MOLM13	viability	CTATTTAATGTAGAAGGTATGG	LHX8	ENSG00000162624	3.5241997944679957	[13,7]	[8,121]	9	hSpCas9	negative selection	5415959
75143151	75143173	1	+	27760321	MOLM13	viability	ACACATCCATTCTACTGACTGG	LHX8	ENSG00000162624	-0.5319206199768424	[282,216]	[105,88]	-3	hSpCas9	negative selection	5415960
75143183	75143205	1	-	27760321	MOLM13	viability	AAGTGATAGACATTCCCCTTGG	LHX8	ENSG00000162624	1.0414335384907143	[2765,2348]	[2235,3575]	7	hSpCas9	negative selection	5415961
75143233	75143255	1	+	27760321	MOLM13	viability	AGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.0664512815480015	[299,241]	[175,118]	0	hSpCas9	negative selection	5415962
75136378	75136401	1	+	27661255	K562	viability	GGGACGAGCTACCAGCGCTCGGG	LHX8	ENSG00000162624	0.09827775650485948	[824,953]	[810,713]	3	dCas9-KRAB	negative selection	5490257
75136809	75136832	1	+	27661255	K562	viability	GGACGGGGCGGAGAGGGTCTGGG	LHX8	ENSG00000162624	-0.15637731272647346	[937,975]	[726,649]	-5	dCas9-KRAB	negative selection	5490258
75136865	75136888	1	+	27661255	K562	viability	GCAGGGCCGCAAGACTTCTGGGG	LHX8	ENSG00000162624	0.008235143473067197	[465,406]	[357,345]	0	dCas9-KRAB	negative selection	5490259
75136886	75136909	1	+	27661255	K562	viability	GGTCCGAATAGGTCAGGGGTCGG	LHX8	ENSG00000162624	0.049981449542776835	[899,777]	[774,627]	1	dCas9-KRAB	negative selection	5490260
75136468	75136491	1	-	27661255	K562	viability	GGCAGCGCGTGCAGCCGTCACGG	LHX8	ENSG00000162624	0.03985909364211887	[828,833]	[753,621]	1	dCas9-KRAB	negative selection	5490261
75136633	75136656	1	+	27260156	BXPC3	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.37920894414763606	[144]	[177,188,196,229]	7	hSpCas9	negative selection	5552595
75136644	75136667	1	-	27260156	BXPC3	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.2651781273037407	[373]	[468,434,490,485]	6	hSpCas9	negative selection	5552596
75140993	75141016	1	-	27260156	BXPC3	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.07789322969494233	[644]	[591,682,822,767]	1	hSpCas9	negative selection	5552597
75143125	75143148	1	+	27260156	BXPC3	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.8371163708066187	[252]	[165,142,117,163]	-9	hSpCas9	negative selection	5616851
75143280	75143303	1	-	27260156	BXPC3	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.04887763447680715	[236]	[152,240,272,307]	-1	hSpCas9	negative selection	5616852
75137240	75137263	1	+	27260156	BXPC3	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.184520765121346	[464]	[454,417,415,414]	-4	hSpCas9	negative selection	5616853
75136633	75136656	1	+	27260156	A673	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.4187457530730798	[144]	[271,161,262,239]	8	hSpCas9	negative selection	5673846
75136644	75136667	1	-	27260156	A673	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.28073807905038894	[373]	[676,455,502,563]	6	hSpCas9	negative selection	5673847
75140993	75141016	1	-	27260156	A673	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.12486009604267612	[644]	[778,585,748,737]	-3	hSpCas9	negative selection	5673848
75143125	75143148	1	+	27260156	A673	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.44942435405878967	[252]	[162,208,248,263]	-8	hSpCas9	negative selection	5738102
75143280	75143303	1	-	27260156	A673	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.25495206492451894	[236]	[305,233,180,240]	-6	hSpCas9	negative selection	5738103
75137240	75137263	1	+	27260156	A673	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.03080384098264828	[464]	[666,484,443,608]	0	hSpCas9	negative selection	5738104
75136633	75136656	1	+	27260156	A375	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.08850340304574256	[144]	[210,165,235,112]	1	hSpCas9	negative selection	5795097
75136644	75136667	1	-	27260156	A375	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.3140678958102411	[373]	[384,691,673,449]	4	hSpCas9	negative selection	5795098
75140993	75141016	1	-	27260156	A375	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.011354940936903202	[644]	[789,806,692,709]	0	hSpCas9	negative selection	5795099
75143125	75143148	1	+	27260156	A375	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.642081844893672	[252]	[122,306,258,94]	-7	hSpCas9	negative selection	5859353
75143280	75143303	1	-	27260156	A375	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.031122293260220868	[236]	[228,464,215,206]	0	hSpCas9	negative selection	5859354
75137240	75137263	1	+	27260156	A375	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.22324543074772396	[464]	[443,469,316,610]	-3	hSpCas9	negative selection	5859355
75136633	75136656	1	+	27260156	COLO741	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.7463188812211001	[144]	[259,391,277]	9	hSpCas9	negative selection	5916348
75136644	75136667	1	-	27260156	COLO741	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.43268723115621566	[373]	[717,707,522]	8	hSpCas9	negative selection	5916349
75140993	75141016	1	-	27260156	COLO741	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.04614545023461508	[644]	[941,780,689]	-1	hSpCas9	negative selection	5916350
75143125	75143148	1	+	27260156	COLO741	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.4983176954165074	[252]	[298,249,148]	-8	hSpCas9	negative selection	5980604
75143280	75143303	1	-	27260156	COLO741	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.9568767893417245	[236]	[149,144,170]	-9	hSpCas9	negative selection	5980605
75137240	75137263	1	+	27260156	COLO741	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.08166601156928055	[464]	[593,715,575]	1	hSpCas9	negative selection	5980606
75136633	75136656	1	+	27260156	CAL120	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.9890361545443513	[144]	[412,281,386]	9	hSpCas9	negative selection	6037599
75136644	75136667	1	-	27260156	CAL120	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.17381736299615066	[373]	[344,695,506]	2	hSpCas9	negative selection	6037600
75140993	75141016	1	-	27260156	CAL120	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.011339976490848558	[644]	[715,799,894]	0	hSpCas9	negative selection	6037601
75143125	75143148	1	+	27260156	CAL120	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.5399068610806106	[252]	[105,141,76]	-9	hSpCas9	negative selection	6101855
75143280	75143303	1	-	27260156	CAL120	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-1.2927710596132709	[236]	[204,58,109]	-9	hSpCas9	negative selection	6101856
75137240	75137263	1	+	27260156	CAL120	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.15651528795925582	[464]	[784,335,476]	-2	hSpCas9	negative selection	6101857
75136633	75136656	1	+	27260156	CADOES1	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.25611275401426004	[144]	[139,190,109,204]	4	hSpCas9	negative selection	6158850
75136644	75136667	1	-	27260156	CADOES1	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.48145173846717826	[373]	[483,474,485,497]	7	hSpCas9	negative selection	6158851
75140993	75141016	1	-	27260156	CADOES1	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.2956250717392371	[644]	[616,494,523,311]	-5	hSpCas9	negative selection	6158852
75143125	75143148	1	+	27260156	CADOES1	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.7541465318516509	[252]	[180,161,100,112]	-8	hSpCas9	negative selection	6223106
75143280	75143303	1	-	27260156	CADOES1	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.05343736537853827	[236]	[141,198,213,297]	-1	hSpCas9	negative selection	6223107
75137240	75137263	1	+	27260156	CADOES1	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.2504691062198119	[464]	[286,362,373,432]	-4	hSpCas9	negative selection	6223108
75136633	75136656	1	+	27260156	EWS502	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.2656933442017817	[144]	[117,232,180,213]	4	hSpCas9	negative selection	6280101
75136644	75136667	1	-	27260156	EWS502	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.6158953127222198	[373]	[634,714,556,502]	9	hSpCas9	negative selection	6280102
75140993	75141016	1	-	27260156	EWS502	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.01439015316270631	[644]	[723,746,580,697]	0	hSpCas9	negative selection	6280103
75143125	75143148	1	+	27260156	EWS502	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.6750962789385531	[252]	[123,147,201,205]	-8	hSpCas9	negative selection	6344357
75143280	75143303	1	-	27260156	EWS502	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	0.07313291577135883	[236]	[264,341,192,249]	1	hSpCas9	negative selection	6344358
75137240	75137263	1	+	27260156	EWS502	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.2284097147648907	[464]	[347,399,586,351]	-4	hSpCas9	negative selection	6344359
75136633	75136656	1	+	27260156	EW8	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.330242871205203	[144]	[165,164,157,101]	6	hSpCas9	negative selection	6401352
75136644	75136667	1	-	27260156	EW8	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.24660567028310162	[373]	[372,301,391,365]	4	hSpCas9	negative selection	6401353
75140993	75141016	1	-	27260156	EW8	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.04603257989110693	[644]	[568,581,405,625]	0	hSpCas9	negative selection	6401354
75143125	75143148	1	+	27260156	EW8	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.10424131388925506	[252]	[145,170,257,170]	-2	hSpCas9	negative selection	6465608
75143280	75143303	1	-	27260156	EW8	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.45594204427714424	[236]	[186,118,96,168]	-7	hSpCas9	negative selection	6465609
75137240	75137263	1	+	27260156	EW8	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.0693031795986775	[464]	[537,357,261,313]	-1	hSpCas9	negative selection	6465610
75136633	75136656	1	+	27260156	CORL105	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.40659563844330093	[144]	[343,127,305,140]	7	hSpCas9	negative selection	6522603
75136644	75136667	1	-	27260156	CORL105	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.5541576860381076	[373]	[930,620,625,401]	8	hSpCas9	negative selection	6522604
75140993	75141016	1	-	27260156	CORL105	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.02347499894369115	[644]	[720,891,817,642]	0	hSpCas9	negative selection	6522605
75143125	75143148	1	+	27260156	CORL105	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.4809532900147371	[252]	[275,178,194,198]	-7	hSpCas9	negative selection	6586859
75143280	75143303	1	-	27260156	CORL105	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.4181484888644187	[236]	[224,316,185,97]	-6	hSpCas9	negative selection	6586860
75137240	75137263	1	+	27260156	CORL105	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.0308138627369869	[464]	[658,313,699,581]	0	hSpCas9	negative selection	6586861
75136633	75136656	1	+	27260156	HS294T	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.671634620341858	[144]	[39,45,63,237]	8	hSpCas9	negative selection	6643854
75136644	75136667	1	-	27260156	HS294T	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.4305829022260905	[373]	[237,206,150,174]	6	hSpCas9	negative selection	6643855
75140993	75141016	1	-	27260156	HS294T	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.10684453247102293	[644]	[291,276,191,317]	1	hSpCas9	negative selection	6643856
75143125	75143148	1	+	27260156	HS294T	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.1112278147182892	[252]	[39,33,56,51]	-9	hSpCas9	negative selection	6708110
75143280	75143303	1	-	27260156	HS294T	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.32931256840757905	[236]	[62,47,90,94]	-5	hSpCas9	negative selection	6708111
75137240	75137263	1	+	27260156	HS294T	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.5692910705903383	[464]	[164,100,96,116]	-7	hSpCas9	negative selection	6708112
75136633	75136656	1	+	27260156	HCC44	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.7388413275719543	[144]	[408,124,365,242]	9	hSpCas9	negative selection	6765105
75136644	75136667	1	-	27260156	HCC44	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.27268374341182794	[373]	[579,347,608,547]	4	hSpCas9	negative selection	6765106
75140993	75141016	1	-	27260156	HCC44	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.0682654521785036	[644]	[494,757,907,627]	-1	hSpCas9	negative selection	6765107
75143125	75143148	1	+	27260156	HCC44	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.06777935917058	[252]	[111,153,155,121]	-8	hSpCas9	negative selection	6829361
75143280	75143303	1	-	27260156	HCC44	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.24837190590333447	[236]	[144,230,478,85]	-4	hSpCas9	negative selection	6829362
75137240	75137263	1	+	27260156	HCC44	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.6895690483691876	[464]	[214,289,490,328]	-7	hSpCas9	negative selection	6829363
75136633	75136656	1	+	27260156	G402	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.2850409430944447	[144]	[265,121,252,221]	3	hSpCas9	negative selection	6886356
75136644	75136667	1	-	27260156	G402	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.635304607666435	[373]	[856,460,1011,518]	7	hSpCas9	negative selection	6886357
75140993	75141016	1	-	27260156	G402	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.11595962038069724	[644]	[702,560,703,911]	-1	hSpCas9	negative selection	6886358
75143125	75143148	1	+	27260156	G402	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.8993951061843664	[252]	[171,77,236,169]	-8	hSpCas9	negative selection	6950612
75143280	75143303	1	-	27260156	G402	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.6541708765367231	[236]	[173,171,260,127]	-7	hSpCas9	negative selection	6950613
75137240	75137263	1	+	27260156	G402	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.20370400709142006	[464]	[339,567,462,575]	-3	hSpCas9	negative selection	6950614
75136633	75136656	1	+	27260156	L33	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	-0.12217896018537133	[144]	[80,67,96,132]	-3	hSpCas9	negative selection	7007607
75136644	75136667	1	-	27260156	L33	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	-0.026064968071121575	[373]	[287,138,257,432]	0	hSpCas9	negative selection	7007608
75140993	75141016	1	-	27260156	L33	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.3105176028042198	[644]	[500,248,355,406]	-6	hSpCas9	negative selection	7007609
75143125	75143148	1	+	27260156	L33	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.6969469928464853	[252]	[169,55,101,154]	-9	hSpCas9	negative selection	7071863
75143280	75143303	1	-	27260156	L33	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.49908364821639495	[236]	[155,57,134,158]	-8	hSpCas9	negative selection	7071864
75137240	75137263	1	+	27260156	L33	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.5210363057726005	[464]	[257,165,177,350]	-8	hSpCas9	negative selection	7071865
75136633	75136656	1	+	27260156	K562	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.193419812816231	[144]	[157,171,92,164]	2	hSpCas9	negative selection	7128858
75136644	75136667	1	-	27260156	K562	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.6425378602403181	[373]	[680,349,659,397]	7	hSpCas9	negative selection	7128859
75140993	75141016	1	-	27260156	K562	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.19822515078020692	[644]	[951,711,244,732]	2	hSpCas9	negative selection	7128860
75143125	75143148	1	+	27260156	K562	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.2883143042686318	[252]	[239,322,107,86]	-4	hSpCas9	negative selection	7193114
75143280	75143303	1	-	27260156	K562	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	0.17387919119628592	[236]	[193,304,267,186]	2	hSpCas9	negative selection	7193115
75137240	75137263	1	+	27260156	K562	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.31114417182530185	[464]	[327,693,607,420]	4	hSpCas9	negative selection	7193116
75136633	75136656	1	+	27260156	HT29	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.5726588597704347	[144]	[200,273,251,309]	9	hSpCas9	negative selection	7250109
75136644	75136667	1	-	27260156	HT29	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.34212300886165964	[373]	[566,653,482,599]	6	hSpCas9	negative selection	7250110
75140993	75141016	1	-	27260156	HT29	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.10465820482466742	[644]	[611,875,750,681]	-2	hSpCas9	negative selection	7250111
75143125	75143148	1	+	27260156	HT29	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.7459403341964141	[252]	[129,265,189,152]	-8	hSpCas9	negative selection	7314365
75143280	75143303	1	-	27260156	HT29	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.24543751192838825	[236]	[237,197,348,187]	-5	hSpCas9	negative selection	7314366
75137240	75137263	1	+	27260156	HT29	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.009195721900720464	[464]	[495,736,416,597]	0	hSpCas9	negative selection	7314367
75136633	75136656	1	+	27260156	MHHES1	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	-0.13713111292763047	[144]	[195,164,145,101]	-3	hSpCas9	negative selection	7371360
75136644	75136667	1	-	27260156	MHHES1	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.2283707945876826	[373]	[568,566,545,334]	4	hSpCas9	negative selection	7371361
75140993	75141016	1	-	27260156	MHHES1	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.20621138969719482	[644]	[911,974,744,744]	4	hSpCas9	negative selection	7371362
75143125	75143148	1	+	27260156	MHHES1	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.1713307380080766	[252]	[129,119,126,125]	-9	hSpCas9	negative selection	7435616
75143280	75143303	1	-	27260156	MHHES1	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.44523342435998536	[236]	[260,317,176,72]	-7	hSpCas9	negative selection	7435617
75137240	75137263	1	+	27260156	MHHES1	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.09476971157409066	[464]	[718,491,504,305]	-2	hSpCas9	negative selection	7435618
75136633	75136656	1	+	27260156	MEWO	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.036410564532472156	[144]	[166,85,169]	0	hSpCas9	negative selection	7492611
75136644	75136667	1	-	27260156	MEWO	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.26874193789597045	[373]	[637,313,354]	6	hSpCas9	negative selection	7492612
75140993	75141016	1	-	27260156	MEWO	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.012675268546444851	[644]	[531,500,748]	0	hSpCas9	negative selection	7492613
75143125	75143148	1	+	27260156	MEWO	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.4001329097541466	[252]	[280,127,148]	-7	hSpCas9	negative selection	7556867
75143280	75143303	1	-	27260156	MEWO	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.12870983101045974	[236]	[327,124,179]	-3	hSpCas9	negative selection	7556868
75137240	75137263	1	+	27260156	MEWO	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.13222097350512646	[464]	[475,499,453]	3	hSpCas9	negative selection	7556869
75136633	75136656	1	+	27260156	LNCAPCLONEFGC	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.23699504781988967	[144]	[83,151,237,158]	3	hSpCas9	negative selection	7613862
75136644	75136667	1	-	27260156	LNCAPCLONEFGC	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.6413529031565086	[373]	[620,479,522,489]	8	hSpCas9	negative selection	7613863
75140993	75141016	1	-	27260156	LNCAPCLONEFGC	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.12095052425733949	[644]	[501,512,690,853]	1	hSpCas9	negative selection	7613864
75143125	75143148	1	+	27260156	LNCAPCLONEFGC	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.9970862975667554	[252]	[98,113,83,157]	-8	hSpCas9	negative selection	7678118
75143280	75143303	1	-	27260156	LNCAPCLONEFGC	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.655164002941069	[236]	[126,125,155,139]	-7	hSpCas9	negative selection	7678119
75137240	75137263	1	+	27260156	LNCAPCLONEFGC	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.3999917506833284	[464]	[448,329,241,240]	-6	hSpCas9	negative selection	7678120
75136633	75136656	1	+	27260156	PANC0327	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	-0.017791643295304693	[144]	[111,154,108,127]	0	hSpCas9	negative selection	7735113
75136644	75136667	1	-	27260156	PANC0327	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.31702983639157856	[373]	[460,216,607,398]	5	hSpCas9	negative selection	7735114
75140993	75141016	1	-	27260156	PANC0327	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.3783955525578364	[644]	[693,298,409,398]	-5	hSpCas9	negative selection	7735115
75143125	75143148	1	+	27260156	PANC0327	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.624369650454744	[252]	[191,183,131,73]	-7	hSpCas9	negative selection	7799369
75143280	75143303	1	-	27260156	PANC0327	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	0.3918048892663015	[236]	[175,253,540,128]	6	hSpCas9	negative selection	7799370
75137240	75137263	1	+	27260156	PANC0327	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.42456519113978985	[464]	[621,511,359,733]	6	hSpCas9	negative selection	7799371
75136633	75136656	1	+	27260156	NCIH2009	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.514167297742022	[144]	[218,211,423]	7	hSpCas9	negative selection	7856364
75136644	75136667	1	-	27260156	NCIH2009	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.6601381923332701	[373]	[1242,619,698]	8	hSpCas9	negative selection	7856365
75140993	75141016	1	-	27260156	NCIH2009	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.08838266928703703	[644]	[1067,900,614]	-1	hSpCas9	negative selection	7856366
75143125	75143148	1	+	27260156	NCIH2009	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.1297344948942092	[252]	[159,218,103]	-8	hSpCas9	negative selection	7920620
75143280	75143303	1	-	27260156	NCIH2009	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.5615521461487634	[236]	[223,93,356]	-6	hSpCas9	negative selection	7920621
75137240	75137263	1	+	27260156	NCIH2009	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.416445427241252	[464]	[662,340,492]	-5	hSpCas9	negative selection	7920622
75136633	75136656	1	+	27260156	NCIH1373	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	1.2478332282884934	[144]	[151,190,667,135]	9	hSpCas9	negative selection	7977615
75136644	75136667	1	-	27260156	NCIH1373	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.7350645126426829	[373]	[1060,481,632,181]	7	hSpCas9	negative selection	7977616
75140993	75141016	1	-	27260156	NCIH1373	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.21567757960711875	[644]	[1027,644,562,76]	-2	hSpCas9	negative selection	7977617
75143125	75143148	1	+	27260156	NCIH1373	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.790235776114931	[252]	[212,214,70,41]	-7	hSpCas9	negative selection	8041871
75143280	75143303	1	-	27260156	NCIH1373	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	0.09400339276675751	[236]	[122,50,255,191]	0	hSpCas9	negative selection	8041872
75137240	75137263	1	+	27260156	NCIH1373	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.9123991577373705	[464]	[189,106,376,116]	-7	hSpCas9	negative selection	8041873
75136633	75136656	1	+	27260156	PATU8902	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.8097354303639002	[144]	[455,330,363,244]	8	hSpCas9	negative selection	8098866
75136644	75136667	1	-	27260156	PATU8902	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.5768484035803804	[373]	[852,1108,491,713]	6	hSpCas9	negative selection	8098867
75140993	75141016	1	-	27260156	PATU8902	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.09058436236256912	[644]	[1376,1010,704,761]	0	hSpCas9	negative selection	8098868
75143125	75143148	1	+	27260156	PATU8902	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.1564717864239742	[252]	[148,125,172,181]	-7	hSpCas9	negative selection	8163122
75143280	75143303	1	-	27260156	PATU8902	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	0.0368819861382953	[236]	[535,122,368,308]	0	hSpCas9	negative selection	8163123
75137240	75137263	1	+	27260156	PATU8902	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.6425033407002294	[464]	[874,218,312,248]	-6	hSpCas9	negative selection	8163124
75136633	75136656	1	+	27260156	PANC1	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.33326991194340194	[144]	[205,214,109,111]	5	hSpCas9	negative selection	8220117
75136644	75136667	1	-	27260156	PANC1	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.4567325355850673	[373]	[435,740,390,276]	7	hSpCas9	negative selection	8220118
75140993	75141016	1	-	27260156	PANC1	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.18698306452233643	[644]	[516,674,369,423]	-3	hSpCas9	negative selection	8220119
75143125	75143148	1	+	27260156	PANC1	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.2317389778715806	[252]	[94,110,151,25]	-9	hSpCas9	negative selection	8284373
75143280	75143303	1	-	27260156	PANC1	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.3571509437172018	[236]	[112,161,101,242]	-5	hSpCas9	negative selection	8284374
75137240	75137263	1	+	27260156	PANC1	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.5163223879370963	[464]	[297,482,176,206]	-7	hSpCas9	negative selection	8284375
75136633	75136656	1	+	27260156	PANC0813	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.44019425930787315	[144]	[284,249,168,224]	7	hSpCas9	negative selection	8341368
75136644	75136667	1	-	27260156	PANC0813	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.6836761588366606	[373]	[621,762,710,716]	9	hSpCas9	negative selection	8341369
75140993	75141016	1	-	27260156	PANC0813	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.06826888755431626	[644]	[735,662,926,573]	-1	hSpCas9	negative selection	8341370
75143125	75143148	1	+	27260156	PANC0813	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.9650582449603069	[252]	[154,101,144,203]	-8	hSpCas9	negative selection	8405624
75143280	75143303	1	-	27260156	PANC0813	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.19384278390930576	[236]	[203,214,172,369]	-3	hSpCas9	negative selection	8405625
75137240	75137263	1	+	27260156	PANC0813	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.08682257114848811	[464]	[550,682,418,411]	-1	hSpCas9	negative selection	8405626
75136633	75136656	1	+	27260156	RDES	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.5955750268812849	[144]	[180,265,237,342]	8	hSpCas9	negative selection	8462619
75136644	75136667	1	-	27260156	RDES	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.7666626722007086	[373]	[589,688,887,786]	9	hSpCas9	negative selection	8462620
75140993	75141016	1	-	27260156	RDES	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.008313828729127615	[644]	[567,652,994,813]	0	hSpCas9	negative selection	8462621
75143125	75143148	1	+	27260156	RDES	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.0142650260238448	[252]	[87,235,145,97]	-9	hSpCas9	negative selection	8526875
75143280	75143303	1	-	27260156	RDES	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.4597374345549672	[236]	[141,158,193,327]	-7	hSpCas9	negative selection	8526876
75137240	75137263	1	+	27260156	RDES	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.4421960278246574	[464]	[323,307,519,446]	-6	hSpCas9	negative selection	8526877
75136633	75136656	1	+	27260156	PC3	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	-0.0014415019893743164	[144]	[126,139,186,127]	0	hSpCas9	negative selection	8583870
75136644	75136667	1	-	27260156	PC3	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.5428841361744641	[373]	[349,347,1110,631]	9	hSpCas9	negative selection	8583871
75140993	75141016	1	-	27260156	PC3	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.11248409896326206	[644]	[458,657,1007,390]	-3	hSpCas9	negative selection	8583872
75143125	75143148	1	+	27260156	PC3	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.6327696436608119	[252]	[114,178,236,149]	-8	hSpCas9	negative selection	8648126
75143280	75143303	1	-	27260156	PC3	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.5554172149572072	[236]	[141,140,234,140]	-8	hSpCas9	negative selection	8648127
75137240	75137263	1	+	27260156	PC3	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.15081022764506843	[464]	[326,343,713,393]	-3	hSpCas9	negative selection	8648128
75136633	75136656	1	+	27260156	PATU8988T	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.3477171533137995	[144]	[177,197,182,153]	6	hSpCas9	negative selection	8705121
75136644	75136667	1	-	27260156	PATU8988T	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.39750617289533896	[373]	[336,671,495,411]	6	hSpCas9	negative selection	8705122
75140993	75141016	1	-	27260156	PATU8988T	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.3096825300042667	[644]	[409,645,419,553]	-5	hSpCas9	negative selection	8705123
75143125	75143148	1	+	27260156	PATU8988T	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-1.420909123636569	[252]	[160,55,67,75]	-9	hSpCas9	negative selection	8769377
75143280	75143303	1	-	27260156	PATU8988T	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.2253337636522199	[236]	[177,221,229,151]	-4	hSpCas9	negative selection	8769378
75137240	75137263	1	+	27260156	PATU8988T	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.19048179643218888	[464]	[256,455,537,321]	-3	hSpCas9	negative selection	8769379
75136633	75136656	1	+	27260156	T47D	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.4687794196741657	[144]	[245,200,227,263]	8	hSpCas9	negative selection	8826372
75136644	75136667	1	-	27260156	T47D	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.20526962856520545	[373]	[492,480,603,428]	4	hSpCas9	negative selection	8826373
75140993	75141016	1	-	27260156	T47D	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.024592595496045477	[644]	[721,641,770,937]	0	hSpCas9	negative selection	8826374
75143125	75143148	1	+	27260156	T47D	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.2945131556951215	[252]	[218,216,273,252]	-6	hSpCas9	negative selection	8890628
75143280	75143303	1	-	27260156	T47D	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.37419506585220197	[236]	[220,170,272,188]	-7	hSpCas9	negative selection	8890629
75137240	75137263	1	+	27260156	T47D	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.05405479979622975	[464]	[521,481,478,610]	-1	hSpCas9	negative selection	8890630
75136633	75136656	1	+	27260156	SU8686	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.9274733491281841	[144]	[271,120,310,434]	9	hSpCas9	negative selection	8947623
75136644	75136667	1	-	27260156	SU8686	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.5769387088927906	[373]	[554,410,593,689]	8	hSpCas9	negative selection	8947624
75140993	75141016	1	-	27260156	SU8686	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.10684131896523857	[644]	[561,627,765,842]	1	hSpCas9	negative selection	8947625
75143125	75143148	1	+	27260156	SU8686	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.6744052625176027	[252]	[146,166,120,197]	-7	hSpCas9	negative selection	9011879
75143280	75143303	1	-	27260156	SU8686	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.21686600483701257	[236]	[126,224,293,162]	-4	hSpCas9	negative selection	9011880
75137240	75137263	1	+	27260156	SU8686	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.45769322337247886	[464]	[294,304,297,471]	-6	hSpCas9	negative selection	9011881
75136633	75136656	1	+	27260156	SKES1	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.2857531276778782	[144]	[206,102,228,160]	6	hSpCas9	negative selection	9068874
75136644	75136667	1	-	27260156	SKES1	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.3940621604184593	[373]	[402,526,676,354]	7	hSpCas9	negative selection	9068875
75140993	75141016	1	-	27260156	SKES1	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.20231794116803076	[644]	[475,608,600,540]	-4	hSpCas9	negative selection	9068876
75143125	75143148	1	+	27260156	SKES1	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.5478518743722696	[252]	[127,196,153,202]	-8	hSpCas9	negative selection	9133130
75143280	75143303	1	-	27260156	SKES1	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.562073514347494	[236]	[207,91,186,150]	-8	hSpCas9	negative selection	9133131
75137240	75137263	1	+	27260156	SKES1	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.20596938379766302	[464]	[547,412,371,304]	-4	hSpCas9	negative selection	9133132
75136633	75136656	1	+	27260156	TOV112D	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.5582623649412204	[144]	[154,351,160,215]	8	hSpCas9	negative selection	9190125
75136644	75136667	1	-	27260156	TOV112D	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.6431724696294993	[373]	[552,774,574,482]	9	hSpCas9	negative selection	9190126
75140993	75141016	1	-	27260156	TOV112D	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	0.19707092632556328	[644]	[804,920,586,698]	4	hSpCas9	negative selection	9190127
75143125	75143148	1	+	27260156	TOV112D	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.9064152567181996	[252]	[111,210,126,107]	-9	hSpCas9	negative selection	9254381
75143280	75143303	1	-	27260156	TOV112D	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.7928467644706927	[236]	[134,203,155,70]	-9	hSpCas9	negative selection	9254382
75137240	75137263	1	+	27260156	TOV112D	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.06626094716027262	[464]	[329,540,493,427]	-1	hSpCas9	negative selection	9254383
75136633	75136656	1	+	27260156	TC71	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.26483048903058304	[144]	[157,166,224,196]	6	hSpCas9	negative selection	9311376
75136644	75136667	1	-	27260156	TC71	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.23648838343174083	[373]	[475,460,408,549]	6	hSpCas9	negative selection	9311377
75140993	75141016	1	-	27260156	TC71	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.00025866907876725964	[644]	[646,613,691,820]	0	hSpCas9	negative selection	9311378
75143125	75143148	1	+	27260156	TC71	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.8007571111051124	[252]	[150,136,198,132]	-9	hSpCas9	negative selection	9375632
75143280	75143303	1	-	27260156	TC71	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	-0.35186946937982144	[236]	[171,219,191,213]	-7	hSpCas9	negative selection	9375633
75137240	75137263	1	+	27260156	TC71	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	-0.26857992557206245	[464]	[324,504,294,543]	-6	hSpCas9	negative selection	9375634
75136633	75136656	1	+	27260156	TC32	viability	CGGACTACAGCCCTGGCGGCCGG	LHX8	ENSG00000162624	0.2927728178015656	[144]	[131,77,314,199]	5	hSpCas9	negative selection	9432627
75136644	75136667	1	-	27260156	TC32	viability	TGCGAGTCCTCCCGGCCGCCAGG	LHX8	ENSG00000162624	0.7572565504362224	[373]	[506,546,768,573]	9	hSpCas9	negative selection	9432628
75140993	75141016	1	-	27260156	TC32	viability	GACACCGGACATGCCAGCATAGG	LHX8	ENSG00000162624	-0.264872587476755	[644]	[527,374,598,549]	-5	hSpCas9	negative selection	9432629
75143125	75143148	1	+	27260156	TC32	viability	GGAACTCGCTGCTCTCGATGTGG	LHX8	ENSG00000162624	-0.9180301567774085	[252]	[138,50,204,142]	-9	hSpCas9	negative selection	9496883
75143280	75143303	1	-	27260156	TC32	viability	AGTCATAATGTACTCTGCAGAGG	LHX8	ENSG00000162624	0.19340623016378655	[236]	[177,289,355,187]	3	hSpCas9	negative selection	9496884
75137240	75137263	1	+	27260156	TC32	viability	CGTGGACAAATACCTTCTCAAGG	LHX8	ENSG00000162624	0.0006823735635617407	[464]	[490,246,635,449]	0	hSpCas9	negative selection	9496885
75136656	75136679	1	+	27869803	HPAFII	viability after 27 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-1.126867329646673	[107]	[31,20,NaN]	-6	hSpCas9	negative selection	9535588
75137213	75137236	1	+	27869803	HPAFII	viability after 27 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-1.1174842181163134	[268]	[80,51,NaN]	-6	hSpCas9	negative selection	9535589
75143232	75143255	1	+	27869803	HPAFII	viability after 27 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.1391702964523462	[377]	[168,189,NaN]	-1	hSpCas9	negative selection	9535590
75143923	75143946	1	-	27869803	HPAFII	viability after 27 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.4542835571244641	[378]	[128,392,NaN]	3	hSpCas9	negative selection	9535591
75156981	75157004	1	-	27869803	HPAFII	viability after 27 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.6467386983078461	[165]	[248,42,NaN]	5	hSpCas9	negative selection	9535592
75136656	75136679	1	+	27869803	HPAFII	viability after 15 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-0.3520198080967807	[107]	[159,47,NaN]	-4	hSpCas9	negative selection	9618037
75137213	75137236	1	+	27869803	HPAFII	viability after 15 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.9189153672227908	[268]	[237,99,NaN]	-7	hSpCas9	negative selection	9618038
75143232	75143255	1	+	27869803	HPAFII	viability after 15 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.8515748012562747	[377]	[234,218,NaN]	-7	hSpCas9	negative selection	9618039
75143923	75143946	1	-	27869803	HPAFII	viability after 15 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.813694893416703	[378]	[932,580,NaN]	8	hSpCas9	negative selection	9618040
75156981	75157004	1	-	27869803	HPAFII	viability after 15 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.4156219702056134	[165]	[446,107,NaN]	5	hSpCas9	negative selection	9618041
75136656	75136679	1	+	27869803	ASPC1	viability after 36 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-1.5640679552868217	[317]	[54,15,41]	-8	hSpCas9	negative selection	9700486
75137213	75137236	1	+	27869803	ASPC1	viability after 36 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.42075165915805646	[604]	[141,225,112]	-4	hSpCas9	negative selection	9700487
75143232	75143255	1	+	27869803	ASPC1	viability after 36 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.02430363282464415	[868]	[261,393,269]	0	hSpCas9	negative selection	9700488
75143923	75143946	1	-	27869803	ASPC1	viability after 36 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	1.0378636729646389	[1017]	[614,787,755]	8	hSpCas9	negative selection	9700489
75156981	75157004	1	-	27869803	ASPC1	viability after 36 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	-0.15070776870849023	[329]	[140,140,46]	-1	hSpCas9	negative selection	9700490
75136656	75136679	1	+	27869803	PATU8988S	viability after 35 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	2.062932886220551	[176]	[236,358,NaN]	9	hSpCas9	negative selection	9782935
75137213	75137236	1	+	27869803	PATU8988S	viability after 35 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.3127560773543565	[607]	[369,237,NaN]	3	hSpCas9	negative selection	9782936
75143232	75143255	1	+	27869803	PATU8988S	viability after 35 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.37625597674319333	[837]	[468,406,NaN]	4	hSpCas9	negative selection	9782937
75143923	75143946	1	-	27869803	PATU8988S	viability after 35 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.45339588036161627	[861]	[416,533,NaN]	5	hSpCas9	negative selection	9782938
75156981	75157004	1	-	27869803	PATU8988S	viability after 35 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.6066875755530705	[348]	[230,196,NaN]	6	hSpCas9	negative selection	9782939
75136656	75136679	1	+	27869803	PATU8988S	viability after 31 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	1.4419998555557358	[176]	[178,207,NaN]	9	hSpCas9	negative selection	9865384
75137213	75137236	1	+	27869803	PATU8988S	viability after 31 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.30464895523308566	[607]	[223,160,NaN]	-3	hSpCas9	negative selection	9865385
75143232	75143255	1	+	27869803	PATU8988S	viability after 31 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.5678374016739404	[837]	[427,580,NaN]	6	hSpCas9	negative selection	9865386
75143923	75143946	1	-	27869803	PATU8988S	viability after 31 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.6888896742073229	[861]	[389,762,NaN]	7	hSpCas9	negative selection	9865387
75156981	75157004	1	-	27869803	PATU8988S	viability after 31 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	0.8760319830583623	[348]	[283,218,NaN]	8	hSpCas9	negative selection	9865388
75136656	75136679	1	+	27869803	HPAFII	viability after 35 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-3.1182619723357936	[107]	[10,0,NaN]	-8	hSpCas9	negative selection	9947833
75137213	75137236	1	+	27869803	HPAFII	viability after 35 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-1.3742053492430066	[268]	[60,42,NaN]	-6	hSpCas9	negative selection	9947834
75143232	75143255	1	+	27869803	HPAFII	viability after 35 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	0.40628404651320904	[377]	[286,215,NaN]	2	hSpCas9	negative selection	9947835
75143923	75143946	1	-	27869803	HPAFII	viability after 35 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.45228415673488076	[378]	[111,431,NaN]	3	hSpCas9	negative selection	9947836
75156981	75157004	1	-	27869803	HPAFII	viability after 35 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	1.1101363496074093	[165]	[290,57,NaN]	7	hSpCas9	negative selection	9947837
75136656	75136679	1	+	27869803	HPAFII	viability after 31 days	GAGGACTCGCAAAGGCGCCGGGG	LHX8	ENSG00000162624	-1.8796225217814055	[107]	[26,4,NaN]	-8	hSpCas9	negative selection	10030282
75137213	75137236	1	+	27869803	HPAFII	viability after 31 days	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.7023714357401063	[268]	[98,85,NaN]	-4	hSpCas9	negative selection	10030283
75143232	75143255	1	+	27869803	HPAFII	viability after 31 days	AAGGCAACTTTCCACAGGAGAGG	LHX8	ENSG00000162624	-0.07761447401882038	[377]	[223,175,NaN]	0	hSpCas9	negative selection	10030284
75143923	75143946	1	-	27869803	HPAFII	viability after 31 days	AAGCTGATCTGCTGTAAAGCTGG	LHX8	ENSG00000162624	0.5361765882949463	[378]	[161,467,NaN]	4	hSpCas9	negative selection	10030285
75156981	75157004	1	-	27869803	HPAFII	viability after 31 days	TAACATGGGTGGAGACAGCCTGG	LHX8	ENSG00000162624	1.143531082287632	[165]	[290,112,NaN]	8	hSpCas9	negative selection	10030286
75136648	75136671	1	+	28162770	P31FUJ	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.36330085391197786	[85]	[129]	4	hSpCas9	negative selection	10184353
75137213	75137236	1	+	28162770	P31FUJ	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.8700566085913563	[317]	[682]	8	hSpCas9	negative selection	10184354
75137096	75137119	1	+	28162770	P31FUJ	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	1.1496674324080345	[111]	[291]	9	hSpCas9	negative selection	10184355
75141019	75141042	1	-	28162770	P31FUJ	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.5745527176432255	[199]	[349]	6	hSpCas9	negative selection	10184356
75136626	75136649	1	+	28162770	P31FUJ	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.8011451275089592	[167]	[343]	8	hSpCas9	negative selection	10184357
75137148	75137171	1	-	28162770	P31FUJ	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	0.059055036585168905	[222]	[272]	0	hSpCas9	negative selection	10184358
75137169	75137192	1	-	28162770	P31FUJ	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.3791916913959017	[113]	[102]	-3	hSpCas9	negative selection	10184359
75156974	75156997	1	-	28162770	P31FUJ	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-5.6922338230516765	[43]	[0]	-9	hSpCas9	negative selection	10184360
75157055	75157078	1	+	28162770	P31FUJ	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	-0.26537006687080933	[223]	[218]	-3	hSpCas9	negative selection	10184361
75136609	75136632	1	+	28162770	P31FUJ	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.7038357345881919	[127]	[244]	7	hSpCas9	negative selection	10184362
75136648	75136671	1	+	28162770	TF1	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	NaN	[NaN]	[82]	1	hSpCas9	negative selection	10353719
75137213	75137236	1	+	28162770	TF1	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	NaN	[NaN]	[410]	1	hSpCas9	negative selection	10353720
75137096	75137119	1	+	28162770	TF1	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	NaN	[NaN]	[173]	1	hSpCas9	negative selection	10353721
75141019	75141042	1	-	28162770	TF1	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	NaN	[NaN]	[213]	1	hSpCas9	negative selection	10353722
75136626	75136649	1	+	28162770	TF1	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	NaN	[NaN]	[215]	1	hSpCas9	negative selection	10353723
75137148	75137171	1	-	28162770	TF1	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	NaN	[NaN]	[86]	1	hSpCas9	negative selection	10353724
75137169	75137192	1	-	28162770	TF1	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	NaN	[NaN]	[91]	1	hSpCas9	negative selection	10353725
75156974	75156997	1	-	28162770	TF1	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10353726
75157055	75157078	1	+	28162770	TF1	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	NaN	[NaN]	[102]	1	hSpCas9	negative selection	10353727
75136609	75136632	1	+	28162770	TF1	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	NaN	[NaN]	[150]	1	hSpCas9	negative selection	10353728
75136648	75136671	1	+	28162770	SKM1	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	1.1388277046973168	[27]	[108]	9	hSpCas9	negative selection	10523085
75137213	75137236	1	+	28162770	SKM1	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.028421945927484482	[65]	[118]	0	hSpCas9	negative selection	10523086
75137096	75137119	1	+	28162770	SKM1	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	0.7901822714341751	[34]	[106]	7	hSpCas9	negative selection	10523087
75141019	75141042	1	-	28162770	SKM1	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.7066925830524055	[60]	[175]	6	hSpCas9	negative selection	10523088
75136626	75136649	1	+	28162770	SKM1	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.1426652288657138	[61]	[120]	1	hSpCas9	negative selection	10523089
75137148	75137171	1	-	28162770	SKM1	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-1.1439297929093677	[54]	[43]	-7	hSpCas9	negative selection	10523090
75137169	75137192	1	-	28162770	SKM1	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.2370391973008492	[27]	[41]	-2	hSpCas9	negative selection	10523091
75156974	75156997	1	-	28162770	SKM1	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-0.3625700793847084	[7]	[10]	-3	hSpCas9	negative selection	10523092
75157055	75157078	1	+	28162770	SKM1	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.15938262381064755	[38]	[76]	1	hSpCas9	negative selection	10523093
75136609	75136632	1	+	28162770	SKM1	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.09782795329401128	[36]	[69]	0	hSpCas9	negative selection	10523094
75136648	75136671	1	+	28162770	SKM1	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	1.1388277046973168	[27]	[108]	9	hSpCas9	negative selection	10692451
75137213	75137236	1	+	28162770	SKM1	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.028421945927484482	[65]	[118]	0	hSpCas9	negative selection	10692452
75137096	75137119	1	+	28162770	SKM1	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	0.7901822714341751	[34]	[106]	7	hSpCas9	negative selection	10692453
75141019	75141042	1	-	28162770	SKM1	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.7066925830524055	[60]	[175]	6	hSpCas9	negative selection	10692454
75136626	75136649	1	+	28162770	SKM1	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.1426652288657138	[61]	[120]	1	hSpCas9	negative selection	10692455
75137148	75137171	1	-	28162770	SKM1	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-1.1439297929093677	[54]	[43]	-7	hSpCas9	negative selection	10692456
75137169	75137192	1	-	28162770	SKM1	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.2370391973008492	[27]	[41]	-2	hSpCas9	negative selection	10692457
75156974	75156997	1	-	28162770	SKM1	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-0.3625700793847084	[7]	[10]	-3	hSpCas9	negative selection	10692458
75157055	75157078	1	+	28162770	SKM1	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.15938262381064755	[38]	[76]	1	hSpCas9	negative selection	10692459
75136609	75136632	1	+	28162770	SKM1	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.09782795329401128	[36]	[69]	0	hSpCas9	negative selection	10692460
75136648	75136671	1	+	28162770	PL21	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.21489788478952376	[95]	[35]	-1	hSpCas9	negative selection	10861817
75137213	75137236	1	+	28162770	PL21	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	1.39378068490544	[180]	[206]	9	hSpCas9	negative selection	10861818
75137096	75137119	1	+	28162770	PL21	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	0.5786512377430502	[159]	[103]	5	hSpCas9	negative selection	10861819
75141019	75141042	1	-	28162770	PL21	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.7942854373758119	[260]	[196]	6	hSpCas9	negative selection	10861820
75136626	75136649	1	+	28162770	PL21	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.07559451655101673	[132]	[60]	0	hSpCas9	negative selection	10861821
75137148	75137171	1	-	28162770	PL21	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-1.8687554667217472	[192]	[22]	-8	hSpCas9	negative selection	10861822
75137169	75137192	1	-	28162770	PL21	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-1.500300103651772	[77]	[11]	-7	hSpCas9	negative selection	10861823
75156974	75156997	1	-	28162770	PL21	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	0.5756487495815263	[36]	[23]	5	hSpCas9	negative selection	10861824
75157055	75157078	1	+	28162770	PL21	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.8113677699042818	[126]	[96]	7	hSpCas9	negative selection	10861825
75136609	75136632	1	+	28162770	PL21	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	1.337643138239255	[129]	[142]	9	hSpCas9	negative selection	10861826
75136648	75136671	1	+	28162770	P31FUJ	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.36330085391197786	[85]	[129]	4	hSpCas9	negative selection	11031183
75137213	75137236	1	+	28162770	P31FUJ	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.8700566085913563	[317]	[682]	8	hSpCas9	negative selection	11031184
75137096	75137119	1	+	28162770	P31FUJ	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	1.1496674324080345	[111]	[291]	9	hSpCas9	negative selection	11031185
75141019	75141042	1	-	28162770	P31FUJ	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.5745527176432255	[199]	[349]	6	hSpCas9	negative selection	11031186
75136626	75136649	1	+	28162770	P31FUJ	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.8011451275089592	[167]	[343]	8	hSpCas9	negative selection	11031187
75137148	75137171	1	-	28162770	P31FUJ	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	0.059055036585168905	[222]	[272]	0	hSpCas9	negative selection	11031188
75137169	75137192	1	-	28162770	P31FUJ	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.3791916913959017	[113]	[102]	-3	hSpCas9	negative selection	11031189
75156974	75156997	1	-	28162770	P31FUJ	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-5.6922338230516765	[43]	[0]	-9	hSpCas9	negative selection	11031190
75157055	75157078	1	+	28162770	P31FUJ	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	-0.26537006687080933	[223]	[218]	-3	hSpCas9	negative selection	11031191
75136609	75136632	1	+	28162770	P31FUJ	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.7038357345881919	[127]	[244]	7	hSpCas9	negative selection	11031192
75136648	75136671	1	+	28162770	OCIAML5	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.38351356225815136	[85]	[118]	-3	hSpCas9	negative selection	11200549
75137213	75137236	1	+	28162770	OCIAML5	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.7515597741221949	[127]	[388]	6	hSpCas9	negative selection	11200550
75137096	75137119	1	+	28162770	OCIAML5	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	-0.22403534825095495	[76]	[118]	-2	hSpCas9	negative selection	11200551
75141019	75141042	1	-	28162770	OCIAML5	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.5996293989936949	[101]	[278]	5	hSpCas9	negative selection	11200552
75136626	75136649	1	+	28162770	OCIAML5	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.27282467696381174	[93]	[204]	2	hSpCas9	negative selection	11200553
75137148	75137171	1	-	28162770	OCIAML5	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-0.21979835536448414	[99]	[154]	-2	hSpCas9	negative selection	11200554
75137169	75137192	1	-	28162770	OCIAML5	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	0.41878733942909596	[45]	[110]	3	hSpCas9	negative selection	11200555
75156974	75156997	1	-	28162770	OCIAML5	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-2.173994665751359	[24]	[9]	-8	hSpCas9	negative selection	11200556
75157055	75157078	1	+	28162770	OCIAML5	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.3930459269725345	[107]	[255]	3	hSpCas9	negative selection	11200557
75136609	75136632	1	+	28162770	OCIAML5	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.40091417030587395	[59]	[142]	3	hSpCas9	negative selection	11200558
75136648	75136671	1	+	28162770	EOL1	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.507139367828944	[202]	[151]	4	hSpCas9	negative selection	11369915
75137213	75137236	1	+	28162770	EOL1	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	-0.07545222842946539	[331]	[165]	0	hSpCas9	negative selection	11369916
75137096	75137119	1	+	28162770	EOL1	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	0.42609426410405327	[266]	[188]	4	hSpCas9	negative selection	11369917
75141019	75141042	1	-	28162770	EOL1	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	-0.14903336081057283	[542]	[257]	-1	hSpCas9	negative selection	11369918
75136626	75136649	1	+	28162770	EOL1	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.36412745511217	[305]	[414]	9	hSpCas9	negative selection	11369919
75137148	75137171	1	-	28162770	EOL1	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	0.15460485495805562	[294]	[172]	1	hSpCas9	negative selection	11369920
75137169	75137192	1	-	28162770	EOL1	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-1.3025211369753866	[102]	[21]	-7	hSpCas9	negative selection	11369921
75156974	75156997	1	-	28162770	EOL1	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-1.9405226483433573	[50]	[6]	-8	hSpCas9	negative selection	11369922
75157055	75157078	1	+	28162770	EOL1	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.038005821353818525	[219]	[118]	0	hSpCas9	negative selection	11369923
75136609	75136632	1	+	28162770	EOL1	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.5873512669608985	[153]	[53]	-4	hSpCas9	negative selection	11369924
75136648	75136671	1	+	28162770	MOLM13	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.0616599988579708	[165]	[114]	0	hSpCas9	negative selection	11539281
75137213	75137236	1	+	28162770	MOLM13	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	1.7194281485405434	[272]	[649]	9	hSpCas9	negative selection	11539282
75137096	75137119	1	+	28162770	MOLM13	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	0.36932554706098913	[211]	[197]	2	hSpCas9	negative selection	11539283
75141019	75141042	1	-	28162770	MOLM13	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.74485074542045	[377]	[457]	5	hSpCas9	negative selection	11539284
75136626	75136649	1	+	28162770	MOLM13	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.0084577629072815	[241]	[351]	7	hSpCas9	negative selection	11539285
75137148	75137171	1	-	28162770	MOLM13	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-1.3446088437889847	[280]	[79]	-6	hSpCas9	negative selection	11539286
75137169	75137192	1	-	28162770	MOLM13	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	0.2614385040771523	[104]	[90]	2	hSpCas9	negative selection	11539287
75156974	75156997	1	-	28162770	MOLM13	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-1.8826078655395544	[50]	[9]	-7	hSpCas9	negative selection	11539288
75157055	75157078	1	+	28162770	MOLM13	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.6736030617343962	[260]	[300]	5	hSpCas9	negative selection	11539289
75136609	75136632	1	+	28162770	MOLM13	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.07081842879518407	[132]	[100]	0	hSpCas9	negative selection	11539290
75136648	75136671	1	+	28162770	HEL	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.4045668827779997	[154]	[74]	-3	hSpCas9	negative selection	11708647
75137213	75137236	1	+	28162770	HEL	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.865993335848796	[238]	[278]	7	hSpCas9	negative selection	11708648
75137096	75137119	1	+	28162770	HEL	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	1.0803188999302888	[126]	[171]	8	hSpCas9	negative selection	11708649
75141019	75141042	1	-	28162770	HEL	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	1.1950799111523152	[327]	[480]	9	hSpCas9	negative selection	11708650
75136626	75136649	1	+	28162770	HEL	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.8073695337731562	[181]	[203]	7	hSpCas9	negative selection	11708651
75137148	75137171	1	-	28162770	HEL	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-0.045633993802326064	[252]	[156]	0	hSpCas9	negative selection	11708652
75137169	75137192	1	-	28162770	HEL	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.942223668720799	[101]	[33]	-5	hSpCas9	negative selection	11708653
75156974	75156997	1	-	28162770	HEL	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	0.028028987885148737	[48]	[31]	0	hSpCas9	negative selection	11708654
75157055	75157078	1	+	28162770	HEL	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	-1.158357099585565	[229]	[65]	-6	hSpCas9	negative selection	11708655
75136609	75136632	1	+	28162770	HEL	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	-0.3572611679996429	[129]	[64]	-2	hSpCas9	negative selection	11708656
75136648	75136671	1	+	28162770	MV411	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.4438347635862789	[95]	[109]	4	hSpCas9	negative selection	11878013
75137213	75137236	1	+	28162770	MV411	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.6340466417351017	[204]	[267]	6	hSpCas9	negative selection	11878014
75137096	75137119	1	+	28162770	MV411	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	-0.6494689562531212	[161]	[86]	-4	hSpCas9	negative selection	11878015
75141019	75141042	1	-	28162770	MV411	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.2404847901410085	[207]	[206]	2	hSpCas9	negative selection	11878016
75136626	75136649	1	+	28162770	MV411	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	0.41249679705327175	[164]	[184]	3	hSpCas9	negative selection	11878017
75137148	75137171	1	-	28162770	MV411	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-0.4831725483436074	[150]	[90]	-4	hSpCas9	negative selection	11878018
75137169	75137192	1	-	28162770	MV411	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.771421476468541	[76]	[37]	-5	hSpCas9	negative selection	11878019
75156974	75156997	1	-	28162770	MV411	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-4.706758759604099	[30]	[0]	-9	hSpCas9	negative selection	11878020
75157055	75157078	1	+	28162770	MV411	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	-1.3196030419411184	[159]	[53]	-7	hSpCas9	negative selection	11878021
75136609	75136632	1	+	28162770	MV411	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	2.589543527607768	[70]	[359]	9	hSpCas9	negative selection	11878022
75136648	75136671	1	+	28162770	MONOMAC1	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.7397693264532524	[69]	[133]	7	hSpCas9	negative selection	12047379
75137213	75137236	1	+	28162770	MONOMAC1	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	0.3559827611588482	[136]	[200]	3	hSpCas9	negative selection	12047380
75137096	75137119	1	+	28162770	MONOMAC1	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	-0.6341006526683965	[87]	[64]	-5	hSpCas9	negative selection	12047381
75141019	75141042	1	-	28162770	MONOMAC1	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.1469175541578075	[181]	[230]	1	hSpCas9	negative selection	12047382
75136626	75136649	1	+	28162770	MONOMAC1	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	-0.09012164314304177	[103]	[111]	-1	hSpCas9	negative selection	12047383
75137148	75137171	1	-	28162770	MONOMAC1	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-0.09435118308498959	[121]	[130]	-1	hSpCas9	negative selection	12047384
75137169	75137192	1	-	28162770	MONOMAC1	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	1.0957449021682923	[59]	[146]	8	hSpCas9	negative selection	12047385
75156974	75156997	1	-	28162770	MONOMAC1	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-1.78199934778071	[14]	[4]	-8	hSpCas9	negative selection	12047386
75157055	75157078	1	+	28162770	MONOMAC1	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.018691843995883473	[92]	[107]	0	hSpCas9	negative selection	12047387
75136609	75136632	1	+	28162770	MONOMAC1	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.8145511272156581	[61]	[124]	7	hSpCas9	negative selection	12047388
75136648	75136671	1	+	28162770	OCIAML2	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	0.4458468191955554	[19]	[150]	4	hSpCas9	negative selection	12216745
75137213	75137236	1	+	28162770	OCIAML2	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	1.271873952465475	[25]	[347]	9	hSpCas9	negative selection	12216746
75137096	75137119	1	+	28162770	OCIAML2	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	0.15664348033695932	[27]	[172]	1	hSpCas9	negative selection	12216747
75141019	75141042	1	-	28162770	OCIAML2	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	0.07443994835548218	[54]	[320]	0	hSpCas9	negative selection	12216748
75136626	75136649	1	+	28162770	OCIAML2	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	-0.3885940563761498	[46]	[198]	-3	hSpCas9	negative selection	12216749
75137148	75137171	1	-	28162770	OCIAML2	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	-0.4147765905086437	[37]	[157]	-3	hSpCas9	negative selection	12216750
75137169	75137192	1	-	28162770	OCIAML2	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-0.3186267317971112	[17]	[79]	-3	hSpCas9	negative selection	12216751
75156974	75156997	1	-	28162770	OCIAML2	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	-1.392627313240888	[8]	[18]	-7	hSpCas9	negative selection	12216752
75157055	75157078	1	+	28162770	OCIAML2	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	0.12391872430819295	[24]	[150]	1	hSpCas9	negative selection	12216753
75136609	75136632	1	+	28162770	OCIAML2	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	1.3089801063325388	[14]	[205]	9	hSpCas9	negative selection	12216754
75136648	75136671	1	+	28162770	OCIAML3	viability	GCGGCCGGGAGGACTCGCAAAGG	LHX8	ENSG00000162624	-0.9541832045684887	[42]	[66]	-6	hSpCas9	negative selection	12386111
75137213	75137236	1	+	28162770	OCIAML3	viability	TGTGTGCAACAGTTGCGGCCTGG	LHX8	ENSG00000162624	1.4089456770651843	[60]	[488]	9	hSpCas9	negative selection	12386112
75137096	75137119	1	+	28162770	OCIAML3	viability	GCAGGTGAGCCCCGAGGGAGCGG	LHX8	ENSG00000162624	-2.259588601253604	[45]	[28]	-8	hSpCas9	negative selection	12386113
75141019	75141042	1	-	28162770	OCIAML3	viability	GGAGGTTCTGCAAACACTGCAGG	LHX8	ENSG00000162624	-0.402866152972155	[59]	[136]	-3	hSpCas9	negative selection	12386114
75136626	75136649	1	+	28162770	OCIAML3	viability	GTGCGGGCGGACTACAGCCCTGG	LHX8	ENSG00000162624	1.5455437120746303	[31]	[281]	9	hSpCas9	negative selection	12386115
75137148	75137171	1	-	28162770	OCIAML3	viability	GGCGAGGACGACGGGGACAGCGG	LHX8	ENSG00000162624	0.006896404266014566	[59]	[181]	0	hSpCas9	negative selection	12386116
75137169	75137192	1	-	28162770	OCIAML3	viability	GAGCCCGAGGCCATGGACCGGGG	LHX8	ENSG00000162624	-1.0992429485745854	[21]	[30]	-7	hSpCas9	negative selection	12386117
75156974	75156997	1	-	28162770	OCIAML3	viability	GGTGGAGACAGCCTGGAGGGTGG	LHX8	ENSG00000162624	0.5352753766208034	[7]	[34]	5	hSpCas9	negative selection	12386118
75157055	75157078	1	+	28162770	OCIAML3	viability	GCGCTGCATAGTTATATGGATGG	LHX8	ENSG00000162624	-0.10634234095792194	[45]	[128]	-1	hSpCas9	negative selection	12386119
75136609	75136632	1	+	28162770	OCIAML3	viability	GGGCTCATGTCAGAGGAGTGCGG	LHX8	ENSG00000162624	0.3581638345852216	[22]	[88]	3	hSpCas9	negative selection	12386120