Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4041
• Symbol:LRP5
• Description:LDL receptor related protein 5

DataSource: http://genomecrispr.dkfz.de/#!/results/LRP5

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
68347882	68347905	11	+	26472758	Jiyoye	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.36535520581124636	[34]	[33]	2	hSpCas9	negative selection	92389
68403490	68403513	11	+	26472758	Jiyoye	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	-0.22184229929321816	[132]	[85]	-1	hSpCas9	negative selection	92390
68403503	68403526	11	+	26472758	Jiyoye	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.7190883911402994	[178]	[81]	-5	hSpCas9	negative selection	92391
68410092	68410115	11	+	26472758	Jiyoye	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.6169370746109343	[180]	[88]	-4	hSpCas9	negative selection	92392
68347952	68347975	11	-	26472758	Jiyoye	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-2.8152170398305745	[55]	[5]	-9	hSpCas9	negative selection	92393
68347986	68348009	11	+	26472758	Jiyoye	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	-0.30431952514421456	[392]	[239]	-2	hSpCas9	negative selection	92394
68348136	68348159	11	+	26472758	Jiyoye	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-0.7489438204114084	[77]	[34]	-5	hSpCas9	negative selection	92395
68348196	68348219	11	+	26472758	Jiyoye	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-0.6284485282248478	[122]	[59]	-4	hSpCas9	negative selection	92396
68365658	68365681	11	-	26472758	Jiyoye	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	0.2617449419843096	[72]	[65]	2	hSpCas9	negative selection	92397
68386537	68386560	11	+	26472758	Jiyoye	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	0.26002168772221923	[164]	[148]	2	hSpCas9	negative selection	92398
68347882	68347905	11	+	26472758	KBM7	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.4084864417438181	[135,85]	[29,101]	4	hSpCas9	negative selection	283507
68403490	68403513	11	+	26472758	KBM7	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.10631929292079814	[369,482]	[184,250]	1	hSpCas9	negative selection	283508
68403503	68403526	11	+	26472758	KBM7	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.9422343593122557	[852,405]	[154,143]	-6	hSpCas9	negative selection	283509
68410092	68410115	11	+	26472758	KBM7	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.8832577526839277	[641,317]	[104,130]	-6	hSpCas9	negative selection	283510
68347952	68347975	11	-	26472758	KBM7	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.13642244463374542	[189,83]	[108,31]	1	hSpCas9	negative selection	283511
68347986	68348009	11	+	26472758	KBM7	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.1322418390279445	[1447,1186]	[677,672]	1	hSpCas9	negative selection	283512
68348136	68348159	11	+	26472758	KBM7	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-0.20784895496091682	[179,200]	[61,92]	-2	hSpCas9	negative selection	283513
68348196	68348219	11	+	26472758	KBM7	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	0.08944865994156814	[304,284]	[132,160]	0	hSpCas9	negative selection	283514
68365658	68365681	11	-	26472758	KBM7	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.43216477890577576	[431,467]	[87,220]	-4	hSpCas9	negative selection	283515
68386537	68386560	11	+	26472758	KBM7	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	0.30523104025221015	[574,723]	[409,359]	3	hSpCas9	negative selection	283516
68347882	68347905	11	+	26472758	Raji	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.3000286133159955	[62]	[17]	3	hSpCas9	negative selection	474625
68403490	68403513	11	+	26472758	Raji	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.8317490927601722	[137]	[56]	7	hSpCas9	negative selection	474626
68403503	68403526	11	+	26472758	Raji	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-2.0293746021335135	[386]	[21]	-8	hSpCas9	negative selection	474627
68410092	68410115	11	+	26472758	Raji	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.11281467254993667	[218]	[46]	-1	hSpCas9	negative selection	474628
68347952	68347975	11	-	26472758	Raji	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.8549963737393141	[80]	[33]	7	hSpCas9	negative selection	474629
68347986	68348009	11	+	26472758	Raji	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.20233193942886207	[587]	[156]	2	hSpCas9	negative selection	474630
68348136	68348159	11	+	26472758	Raji	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	1.1073835353735992	[55]	[27]	8	hSpCas9	negative selection	474631
68348196	68348219	11	+	26472758	Raji	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	1.3090173965432501	[119]	[68]	9	hSpCas9	negative selection	474632
68365658	68365681	11	-	26472758	Raji	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.31184176086867776	[229]	[42]	-3	hSpCas9	negative selection	474633
68386537	68386560	11	+	26472758	Raji	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.006632724918056387	[328]	[75]	0	hSpCas9	negative selection	474634
68347882	68347905	11	+	26472758	K562	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	-1.7711781273845717	[92]	[22]	-7	hSpCas9	negative selection	665743
68403490	68403513	11	+	26472758	K562	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	-0.2687205920975725	[430]	[301]	-2	hSpCas9	negative selection	665744
68403503	68403526	11	+	26472758	K562	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-1.9597219891137785	[575]	[124]	-7	hSpCas9	negative selection	665745
68410092	68410115	11	+	26472758	K562	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.21186175384427827	[342]	[249]	-1	hSpCas9	negative selection	665746
68347952	68347975	11	-	26472758	K562	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-1.8144749613871214	[99]	[23]	-7	hSpCas9	negative selection	665747
68347986	68348009	11	+	26472758	K562	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.32827277898509166	[1035]	[1097]	2	hSpCas9	negative selection	665748
68348136	68348159	11	+	26472758	K562	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	0.7038503463037441	[143]	[197]	6	hSpCas9	negative selection	665749
68348196	68348219	11	+	26472758	K562	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-1.3216847458033936	[227]	[76]	-6	hSpCas9	negative selection	665750
68365658	68365681	11	-	26472758	K562	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.42616419860799293	[268]	[168]	-3	hSpCas9	negative selection	665751
68386537	68386560	11	+	26472758	K562	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.5391700364194328	[586]	[340]	-3	hSpCas9	negative selection	665752
68348163	68348186	11	+	26627737	DLD1	viability	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.02630913667191992	[559]	[281,127,129]	0	hSpCas9	negative selection	780673
68357683	68357706	11	+	26627737	DLD1	viability	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.8058037356445242	[1357]	[291,416,55]	-6	hSpCas9	negative selection	780674
68363840	68363863	11	-	26627737	DLD1	viability	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	-0.1471723656987578	[1326]	[440,469,237]	-1	hSpCas9	negative selection	780675
68365636	68365659	11	-	26627737	DLD1	viability	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	1.1276461211197966	[354]	[254,241,231]	9	hSpCas9	negative selection	780676
68386584	68386607	11	+	26627737	DLD1	viability	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.2874996851977195	[312]	[92,78,69]	-3	hSpCas9	negative selection	780677
68403487	68403510	11	+	26627737	DLD1	viability	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	0.2732857121111334	[621]	[321,225,166]	3	hSpCas9	negative selection	780681
68348163	68348186	11	+	26627737	GBM cells	viability after 5 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.015015174990646762	[243]	[138,119]	0	hSpCas9	negative selection	862988
68357683	68357706	11	+	26627737	GBM cells	viability after 5 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.20501849880033196	[445]	[187,226]	-3	hSpCas9	negative selection	862989
68363840	68363863	11	-	26627737	GBM cells	viability after 5 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.339486466271667	[363]	[246,246]	5	hSpCas9	negative selection	862990
68365636	68365659	11	-	26627737	GBM cells	viability after 5 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.757558025640144	[299]	[298,244]	8	hSpCas9	negative selection	862991
68386584	68386607	11	+	26627737	GBM cells	viability after 5 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.11938694185725837	[237]	[106,127]	-2	hSpCas9	negative selection	862992
68403487	68403510	11	+	26627737	GBM cells	viability after 5 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	0.16262735582775223	[353]	[194,229]	2	hSpCas9	negative selection	862996
68348163	68348186	11	+	26627737	GBM cells	viability after 13 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.3275550297207141	[243]	[153,175]	4	hSpCas9	negative selection	945303
68357683	68357706	11	+	26627737	GBM cells	viability after 13 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.17986009466571784	[445]	[222,205]	-2	hSpCas9	negative selection	945304
68363840	68363863	11	-	26627737	GBM cells	viability after 13 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.4444294278565737	[363]	[324,222]	5	hSpCas9	negative selection	945305
68365636	68365659	11	-	26627737	GBM cells	viability after 13 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	1.0791482463993345	[299]	[285,390]	9	hSpCas9	negative selection	945306
68386584	68386607	11	+	26627737	GBM cells	viability after 13 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.11982289092457224	[237]	[152,129]	1	hSpCas9	negative selection	945307
68403487	68403510	11	+	26627737	GBM cells	viability after 13 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.056933405740425824	[353]	[225,150]	0	hSpCas9	negative selection	945311
68348163	68348186	11	+	26627737	GBM cells	viability after 21 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.4534100166008988	[243]	[192,170]	4	hSpCas9	negative selection	1027618
68357683	68357706	11	+	26627737	GBM cells	viability after 21 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.18599811397830146	[445]	[283,267]	2	hSpCas9	negative selection	1027619
68363840	68363863	11	-	26627737	GBM cells	viability after 21 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.25772829606325176	[363]	[237,234]	2	hSpCas9	negative selection	1027620
68365636	68365659	11	-	26627737	GBM cells	viability after 21 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	1.3442431819602094	[299]	[429,398]	9	hSpCas9	negative selection	1027621
68386584	68386607	11	+	26627737	GBM cells	viability after 21 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.6143673029987019	[237]	[210,185]	6	hSpCas9	negative selection	1027622
68403487	68403510	11	+	26627737	GBM cells	viability after 21 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.13652758391025688	[353]	[175,173]	-1	hSpCas9	negative selection	1027626
68348163	68348186	11	+	26627737	RPE1	viability after 9 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.21944320814580184	[813]	[180,445]	1	hSpCas9	negative selection	1109933
68357683	68357706	11	+	26627737	RPE1	viability after 9 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.03325954861579328	[1255]	[261,541]	0	hSpCas9	negative selection	1109934
68363840	68363863	11	-	26627737	RPE1	viability after 9 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.040722182726782075	[2305]	[794,674]	0	hSpCas9	negative selection	1109935
68365636	68365659	11	-	26627737	RPE1	viability after 9 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.7217087874698935	[946]	[515,453]	5	hSpCas9	negative selection	1109936
68386584	68386607	11	+	26627737	RPE1	viability after 9 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.593562612341261	[557]	[222,315]	4	hSpCas9	negative selection	1109937
68403487	68403510	11	+	26627737	RPE1	viability after 9 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.2253009979374947	[1415]	[421,323]	-1	hSpCas9	negative selection	1109941
68348163	68348186	11	+	26627737	RPE1	viability after 12 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-1.2159938396426615	[813]	[47,142]	-7	hSpCas9	negative selection	1192248
68357683	68357706	11	+	26627737	RPE1	viability after 12 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.15424745093905146	[1255]	[259,348]	-1	hSpCas9	negative selection	1192249
68363840	68363863	11	-	26627737	RPE1	viability after 12 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.07467394407157757	[2305]	[837,455]	0	hSpCas9	negative selection	1192250
68365636	68365659	11	-	26627737	RPE1	viability after 12 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.624756856581604	[946]	[470,308]	4	hSpCas9	negative selection	1192251
68386584	68386607	11	+	26627737	RPE1	viability after 12 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.9444890449500891	[557]	[254,323]	6	hSpCas9	negative selection	1192252
68403487	68403510	11	+	26627737	RPE1	viability after 12 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.19981082507184245	[1415]	[355,304]	-1	hSpCas9	negative selection	1192256
68348163	68348186	11	+	26627737	RPE1	viability after 15 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.10573013492679412	[813]	[101,321]	0	hSpCas9	negative selection	1274563
68357683	68357706	11	+	26627737	RPE1	viability after 15 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.2964786966739893	[1255]	[328,250]	-2	hSpCas9	negative selection	1274564
68363840	68363863	11	-	26627737	RPE1	viability after 15 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.5643753182554165	[2305]	[1323,617]	3	hSpCas9	negative selection	1274565
68365636	68365659	11	-	26627737	RPE1	viability after 15 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.41550574566720916	[946]	[424,291]	2	hSpCas9	negative selection	1274566
68386584	68386607	11	+	26627737	RPE1	viability after 15 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.6198318695590401	[557]	[210,272]	4	hSpCas9	negative selection	1274567
68403487	68403510	11	+	26627737	RPE1	viability after 15 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	0.25086612378808293	[1415]	[609,347]	1	hSpCas9	negative selection	1274571
68348163	68348186	11	+	26627737	RPE1	viability after 18 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.17908171314125323	[813]	[210,288]	1	hSpCas9	negative selection	1356878
68357683	68357706	11	+	26627737	RPE1	viability after 18 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.6578034399792455	[1255]	[454,619]	4	hSpCas9	negative selection	1356879
68363840	68363863	11	-	26627737	RPE1	viability after 18 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.29639453597707766	[2305]	[858,662]	2	hSpCas9	negative selection	1356880
68365636	68365659	11	-	26627737	RPE1	viability after 18 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.41733823879566495	[946]	[451,222]	2	hSpCas9	negative selection	1356881
68386584	68386607	11	+	26627737	RPE1	viability after 18 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	1.2500883024209357	[557]	[377,336]	7	hSpCas9	negative selection	1356882
68403487	68403510	11	+	26627737	RPE1	viability after 18 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.3939315714478423	[1415]	[343,233]	-2	hSpCas9	negative selection	1356886
68348163	68348186	11	+	26627737	HeLa	viability after 8 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	1.0531812873894135	[157]	[160,38,225]	7	hSpCas9	negative selection	1439193
68357683	68357706	11	+	26627737	HeLa	viability after 8 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.1836453078257192	[771]	[525,292,358]	1	hSpCas9	negative selection	1439194
68363840	68363863	11	-	26627737	HeLa	viability after 8 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.8495519018909548	[555]	[368,604,326]	7	hSpCas9	negative selection	1439195
68365636	68365659	11	-	26627737	HeLa	viability after 8 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.3519482327896875	[540]	[303,369,232]	3	hSpCas9	negative selection	1439196
68386584	68386607	11	+	26627737	HeLa	viability after 8 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.09367177514912184	[272]	[103,170,60]	-1	hSpCas9	negative selection	1439197
68403487	68403510	11	+	26627737	HeLa	viability after 8 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	0.09136796176269879	[516]	[143,225,321]	0	hSpCas9	negative selection	1439201
68348163	68348186	11	+	26627737	HeLa	viability after 12 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	1.1205367609255645	[157]	[298,70,67]	7	hSpCas9	negative selection	1521508
68357683	68357706	11	+	26627737	HeLa	viability after 12 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.07440234522381473	[771]	[245,211,458]	0	hSpCas9	negative selection	1521509
68363840	68363863	11	-	26627737	HeLa	viability after 12 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	1.050215539656206	[555]	[266,441,715]	7	hSpCas9	negative selection	1521510
68365636	68365659	11	-	26627737	HeLa	viability after 12 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.4780900051161708	[540]	[274,284,375]	4	hSpCas9	negative selection	1521511
68386584	68386607	11	+	26627737	HeLa	viability after 12 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.06394707716339154	[272]	[152,89,83]	0	hSpCas9	negative selection	1521512
68403487	68403510	11	+	26627737	HeLa	viability after 12 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.15866931374715018	[516]	[255,163,158]	-1	hSpCas9	negative selection	1521516
68348163	68348186	11	+	26627737	HeLa	viability after 15 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.45329486873748837	[157]	[236,0,18]	4	hSpCas9	negative selection	1603823
68357683	68357706	11	+	26627737	HeLa	viability after 15 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.03760258635431979	[771]	[325,253,340]	0	hSpCas9	negative selection	1603824
68363840	68363863	11	-	26627737	HeLa	viability after 15 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	1.135827184504697	[555]	[351,608,535]	7	hSpCas9	negative selection	1603825
68365636	68365659	11	-	26627737	HeLa	viability after 15 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.6453187889475187	[540]	[358,211,471]	5	hSpCas9	negative selection	1603826
68386584	68386607	11	+	26627737	HeLa	viability after 15 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.3433544322281318	[272]	[90,271,53]	3	hSpCas9	negative selection	1603827
68403487	68403510	11	+	26627737	HeLa	viability after 15 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.29130716092662834	[516]	[145,201,167]	-3	hSpCas9	negative selection	1603831
68348163	68348186	11	+	26627737	HeLa	viability after 18 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.28481066907451	[157]	[139,0,18]	2	hSpCas9	negative selection	1686138
68357683	68357706	11	+	26627737	HeLa	viability after 18 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.042917717596072213	[771]	[223,200,340]	0	hSpCas9	negative selection	1686139
68363840	68363863	11	-	26627737	HeLa	viability after 18 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	1.1286598232095415	[555]	[221,515,535]	7	hSpCas9	negative selection	1686140
68365636	68365659	11	-	26627737	HeLa	viability after 18 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.6643325900192723	[540]	[238,188,471]	5	hSpCas9	negative selection	1686141
68386584	68386607	11	+	26627737	HeLa	viability after 18 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.35573388185993937	[272]	[61,226,53]	3	hSpCas9	negative selection	1686142
68403487	68403510	11	+	26627737	HeLa	viability after 18 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.29549715064447796	[516]	[97,165,167]	-3	hSpCas9	negative selection	1686146
68348163	68348186	11	+	26627737	HCT116	viability after 6 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	1.7090405926340748	[395]	[325,135]	8	hSpCas9	negative selection	1768453
68357683	68357706	11	+	26627737	HCT116	viability after 6 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.733118479391182	[1368]	[320,377]	4	hSpCas9	negative selection	1768454
68363840	68363863	11	-	26627737	HCT116	viability after 6 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	-0.1287185700771022	[1319]	[183,192]	0	hSpCas9	negative selection	1768455
68365636	68365659	11	-	26627737	HCT116	viability after 6 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.9998852831020829	[933]	[185,352]	5	hSpCas9	negative selection	1768456
68386584	68386607	11	+	26627737	HCT116	viability after 6 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	1.781342648103744	[433]	[113,300]	8	hSpCas9	negative selection	1768457
68403487	68403510	11	+	26627737	HCT116	viability after 6 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.7424286361785168	[653]	[132,21]	-4	hSpCas9	negative selection	1768461
68348163	68348186	11	+	26627737	HCT116	viability after 8 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.5233674441191571	[324]	[103,109,158]	-6	hSpCas9	negative selection	1850768
68357683	68357706	11	+	26627737	HCT116	viability after 8 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.3364451109425018	[415]	[272,222,370]	3	hSpCas9	negative selection	1850769
68363840	68363863	11	-	26627737	HCT116	viability after 8 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	-0.5424312182695491	[617]	[197,284,217]	-6	hSpCas9	negative selection	1850770
68365636	68365659	11	-	26627737	HCT116	viability after 8 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.19333669033359147	[484]	[230,346,336]	2	hSpCas9	negative selection	1850771
68386584	68386607	11	+	26627737	HCT116	viability after 8 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.35739610163067553	[333]	[181,133,115]	-4	hSpCas9	negative selection	1850772
68403487	68403510	11	+	26627737	HCT116	viability after 8 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.023034262015543427	[430]	[261,230,208]	0	hSpCas9	negative selection	1850776
68348163	68348186	11	+	26627737	HCT116	viability after 9 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.8719236977965279	[395]	[159,219]	6	hSpCas9	negative selection	1933083
68357683	68357706	11	+	26627737	HCT116	viability after 9 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.1412675166014823	[1368]	[474,217]	-1	hSpCas9	negative selection	1933084
68363840	68363863	11	-	26627737	HCT116	viability after 9 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	-0.4592016154417703	[1319]	[371,164]	-3	hSpCas9	negative selection	1933085
68365636	68365659	11	-	26627737	HCT116	viability after 9 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.09245592662862956	[933]	[304,234]	0	hSpCas9	negative selection	1933086
68386584	68386607	11	+	26627737	HCT116	viability after 9 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-1.7395852995976573	[433]	[27,39]	-8	hSpCas9	negative selection	1933087
68403487	68403510	11	+	26627737	HCT116	viability after 9 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.009477534120905393	[653]	[268,97]	0	hSpCas9	negative selection	1933091
68348163	68348186	11	+	26627737	HCT116	viability after 12 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.057446199081120725	[324]	[147,130,213]	0	hSpCas9	negative selection	2015398
68357683	68357706	11	+	26627737	HCT116	viability after 12 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.39477547008971353	[415]	[186,241,440]	4	hSpCas9	negative selection	2015399
68363840	68363863	11	-	26627737	HCT116	viability after 12 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.37316175633479354	[617]	[332,476,460]	4	hSpCas9	negative selection	2015400
68365636	68365659	11	-	26627737	HCT116	viability after 12 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	-0.09821544797930526	[484]	[222,293,199]	-1	hSpCas9	negative selection	2015401
68386584	68386607	11	+	26627737	HCT116	viability after 12 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.46166446129336314	[333]	[72,120,192]	-5	hSpCas9	negative selection	2015402
68403487	68403510	11	+	26627737	HCT116	viability after 12 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	0.3523698913926787	[430]	[232,353,286]	3	hSpCas9	negative selection	2015406
68348163	68348186	11	+	26627737	HCT116	viability after 15 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.5285513372028519	[324]	[127,46,211]	-5	hSpCas9	negative selection	2097713
68357683	68357706	11	+	26627737	HCT116	viability after 15 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.41094903638542196	[415]	[262,342,339]	4	hSpCas9	negative selection	2097714
68363840	68363863	11	-	26627737	HCT116	viability after 15 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.19849970835346453	[617]	[403,376,439]	2	hSpCas9	negative selection	2097715
68365636	68365659	11	-	26627737	HCT116	viability after 15 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	-0.04907636505588864	[484]	[340,256,218]	0	hSpCas9	negative selection	2097716
68386584	68386607	11	+	26627737	HCT116	viability after 15 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.6224333624400942	[333]	[155,128,92]	-6	hSpCas9	negative selection	2097717
68403487	68403510	11	+	26627737	HCT116	viability after 15 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	0.1328502434355544	[430]	[220,310,275]	1	hSpCas9	negative selection	2097721
68348163	68348186	11	+	26627737	HCT116	viability after 18 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	0.41042004761478346	[324]	[229,169,229]	3	hSpCas9	negative selection	2180028
68357683	68357706	11	+	26627737	HCT116	viability after 18 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	0.4696583272917753	[415]	[296,240,300]	4	hSpCas9	negative selection	2180029
68363840	68363863	11	-	26627737	HCT116	viability after 18 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.2101163088042015	[617]	[485,260,292]	1	hSpCas9	negative selection	2180030
68365636	68365659	11	-	26627737	HCT116	viability after 18 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.5276693601833952	[484]	[249,425,331]	4	hSpCas9	negative selection	2180031
68386584	68386607	11	+	26627737	HCT116	viability after 18 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-1.0558058129732955	[333]	[60,58,115]	-7	hSpCas9	negative selection	2180032
68403487	68403510	11	+	26627737	HCT116	viability after 18 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	0.12296682726754993	[430]	[259,150,276]	1	hSpCas9	negative selection	2180036
68347855	68347879	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CTCCTGCTATTTGCCAACCGCCGG	LRP5	ENSG00000162337	-0.4505478115720671	[4256,2942,3184]	[0,0,0]	-4	hSpCas9	positive selection	2381088
68357678	68357702	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	ACGCCCCGGATTGAGCGGGCAGGG	LRP5	ENSG00000162337	-0.08870480368482134	[2801,2444,2795]	[0,0,0]	0	hSpCas9	positive selection	2381089
68347868	68347892	11	+	24717434	HeLa	essential genes for diphteria toxin toxicity	CCAACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	-1.1592230328463677	[5819,6009,5057]	[0,0,0]	-8	hSpCas9	positive selection	2381090
68347855	68347879	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTCCTGCTATTTGCCAACCGCCGG	LRP5	ENSG00000162337	-0.45060680977022693	[4256,2942,3184]	[0,0,0]	-5	hSpCas9	positive selection	2382346
68347855	68347879	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTCCTGCTATTTGCCAACCGCCGG	LRP5	ENSG00000162337	-0.45060680977022693	[4256,2942,3184]	[0,0,0]	-5	hSpCas9	positive selection	2382347
68347855	68347879	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CTCCTGCTATTTGCCAACCGCCGG	LRP5	ENSG00000162337	-0.45060680977022693	[4256,2942,3184]	[0,0,0]	-5	hSpCas9	positive selection	2382348
68357678	68357702	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACGCCCCGGATTGAGCGGGCAGGG	LRP5	ENSG00000162337	3.7527161159201	[2801,2444,2795]	[40,0,0]	6	hSpCas9	positive selection	2382349
68357678	68357702	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACGCCCCGGATTGAGCGGGCAGGG	LRP5	ENSG00000162337	3.7527161159201	[2801,2444,2795]	[40,0,0]	6	hSpCas9	positive selection	2382350
68357678	68357702	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	ACGCCCCGGATTGAGCGGGCAGGG	LRP5	ENSG00000162337	3.7527161159201	[2801,2444,2795]	[40,0,0]	6	hSpCas9	positive selection	2382351
68347868	68347892	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCAACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	2.89906743605723	[5819,6009,5057]	[0,47,0]	5	hSpCas9	positive selection	2382352
68347868	68347892	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCAACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	2.89906743605723	[5819,6009,5057]	[0,47,0]	5	hSpCas9	positive selection	2382353
68347868	68347892	11	+	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCAACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	2.89906743605723	[5819,6009,5057]	[0,47,0]	5	hSpCas9	positive selection	2382354
68398847	68398870	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GTCTCAGCCTCCTGAGTAGCGGG	LRP5	ENSG00000162337	-0.29935217365489764	[71,81]	[9,16]	-1	dCas9-VP64	positive selection	2389878
68404812	68404835	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TACAAAAAATTAGCCGGGTGCGG	LRP5	ENSG00000162337	0.005790697324581817	[8,20]	[2,2]	0	dCas9-VP64	positive selection	2434896
68428818	68428841	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGCCTGTAATCTCAGCACTTTAG	LRP5	ENSG00000162337	-0.6796005969874881	[92,259]	[10,38]	-3	dCas9-VP64	positive selection	2447599
68407242	68407265	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAACCTCCGCCTCCCAGG	LRP5	ENSG00000162337	0.6259309833286419	[228,309]	[35,151]	2	dCas9-VP64	positive selection	2450537
68393528	68393551	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCACTTTGGGAGGCCGTGG	LRP5	ENSG00000162337	-0.9342473761319348	[1,66]	[1,4]	-5	dCas9-VP64	positive selection	2466397
68318157	68318180	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGGCTGAGGCAGGAGAAAGG	LRP5	ENSG00000162337	1.7244712313844854	[32,17]	[27,7]	6	dCas9-VP64	positive selection	2468595
68358323	68358346	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCTGGTCTCAAACTCCTAAG	LRP5	ENSG00000162337	1.754298476960665	[131,229]	[162,104]	6	dCas9-VP64	positive selection	2469860
68427635	68427658	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	ACGCCACTGCACTCCAGCCTAGG	LRP5	ENSG00000162337	0.6631647882125523	[138,30]	[44,11]	3	dCas9-VP64	positive selection	2473802
68443372	68443395	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTTGGGAGTCTGAAG	LRP5	ENSG00000162337	-0.15146719444215884	[19,99]	[2,20]	0	dCas9-VP64	positive selection	2477291
68398847	68398870	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GTCTCAGCCTCCTGAGTAGCGGG	LRP5	ENSG00000162337	0.6576184974956476	[246,231]	[69,172]	5	dCas9-VP64	positive selection	2485133
68404812	68404835	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TACAAAAAATTAGCCGGGTGCGG	LRP5	ENSG00000162337	1.0784968234287284	[5,24]	[2,16]	7	dCas9-VP64	positive selection	2530151
68428818	68428841	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGCCTGTAATCTCAGCACTTTAG	LRP5	ENSG00000162337	0.2134968510682193	[79,136]	[55,26]	1	dCas9-VP64	positive selection	2542854
68407242	68407265	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAACCTCCGCCTCCCAGG	LRP5	ENSG00000162337	0.8832307312434098	[227,267]	[69,222]	6	dCas9-VP64	positive selection	2545792
68393528	68393551	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCACTTTGGGAGGCCGTGG	LRP5	ENSG00000162337	0.9976288697164769	[174,155]	[180,39]	6	dCas9-VP64	positive selection	2561652
68318157	68318180	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGGCTGAGGCAGGAGAAAGG	LRP5	ENSG00000162337	-0.1093774260535414	[64,117]	[17,35]	-1	dCas9-VP64	positive selection	2563850
68358323	68358346	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCTGGTCTCAAACTCCTAAG	LRP5	ENSG00000162337	0.3544513964898359	[322,573]	[129,237]	3	dCas9-VP64	positive selection	2565115
68427635	68427658	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	ACGCCACTGCACTCCAGCCTAGG	LRP5	ENSG00000162337	-0.07877572482445189	[107,69]	[28,25]	0	dCas9-VP64	positive selection	2569057
68443372	68443395	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTTGGGAGTCTGAAG	LRP5	ENSG00000162337	-0.5794237439586355	[437,196]	[106,34]	-6	dCas9-VP64	positive selection	2572546
68347872	68347895	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCACCAGCCGTACGTCCCGGCGG	LRP5	ENSG00000162337	0.09600583852033863	[3,3]	[3,2]	2	hSpCas9	positive selection	3000004
68348020	68348043	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGACCTACCTGAACCAGACGG	LRP5	ENSG00000162337	-0.09901250475371531	[5,5]	[4,3]	-1	hSpCas9	positive selection	3000005
68410093	68410116	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.6296702802525016	[2,2]	[2,0]	-7	hSpCas9	positive selection	3000006
68409965	68409988	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTTTGGCCTTGACTACCCCGAGG	LRP5	ENSG00000162337	-0.17396255514977263	[3,3]	[2,1]	-2	hSpCas9	positive selection	3000007
68347872	68347895	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCACCAGCCGTACGTCCCGGCGG	LRP5	ENSG00000162337	-0.6434626230813961	[3,3]	[1,0]	-8	hSpCas9	positive selection	3067862
68348020	68348043	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGACCTACCTGAACCAGACGG	LRP5	ENSG00000162337	0.3625426241734095	[5,5]	[6,3]	6	hSpCas9	positive selection	3067863
68410093	68410116	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.1902991126254967	[2,2]	[2,0]	-3	hSpCas9	positive selection	3067864
68409965	68409988	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTTTGGCCTTGACTACCCCGAGG	LRP5	ENSG00000162337	0.5325646742802663	[3,3]	[1,4]	8	hSpCas9	positive selection	3067865
68365627	68365650		-	24336571	A375	resistance to PLX after 7 days	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.22406724936337533	[9,8]	[10,11]	6	hSpCas9	positive selection	3125211
68347875	68347898		-	24336571	A375	resistance to PLX after 7 days	CGTCCACCAGCCGTACGTCCCGG	LRP5	ENSG00000162337	-0.893701798596181	[12,9]	[6,4]	-9	hSpCas9	positive selection	3125212
68347879	68347902		+	24336571	A375	resistance to PLX after 7 days	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.3058789565213319	[5,7]	[4,5]	-8	hSpCas9	positive selection	3125213
68365627	68365650		-	24336571	A375	resistance to PLX after 14 days	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.30112660852317213	[8,9]	[3,5]	3	hSpCas9	positive selection	3183004
68347875	68347898		-	24336571	A375	resistance to PLX after 14 days	CGTCCACCAGCCGTACGTCCCGG	LRP5	ENSG00000162337	-0.6364701160629255	[8,12]	[3,1]	-7	hSpCas9	positive selection	3183005
68347879	68347902		+	24336571	A375	resistance to PLX after 14 days	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.23273618221688896	[7,7]	[2,2]	-3	hSpCas9	positive selection	3183006
68365627	68365650		-	24336571	A375	viability after 7 days	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.33573414536506696	[7]	[9,8]	5	hSpCas9	negative selection	3240797
68347875	68347898		-	24336571	A375	viability after 7 days	CGTCCACCAGCCGTACGTCCCGG	LRP5	ENSG00000162337	2.2273574502896807	[1]	[12,9]	9	hSpCas9	negative selection	3240798
68347879	68347902		+	24336571	A375	viability after 7 days	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	1.5532954511327541	[1]	[5,7]	9	hSpCas9	negative selection	3240799
68365627	68365650		-	24336571	A375	viability after 14 days	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.30758531970818376	[7]	[8,9]	4	hSpCas9	negative selection	3298590
68347875	68347898		-	24336571	A375	viability after 14 days	CGTCCACCAGCCGTACGTCCCGG	LRP5	ENSG00000162337	2.216289387734231	[1]	[8,12]	9	hSpCas9	negative selection	3298591
68347879	68347902		+	24336571	A375	viability after 14 days	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	1.8539385110740376	[1]	[7,7]	9	hSpCas9	negative selection	3298592
68386614	68386637	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	1.5024387092823666	[53,53]	[0,0]	6	hSpCas9	positive selection	3377578
68365627	68365650	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.48914188666890873	[108,108]	[0,0]	2	hSpCas9	positive selection	3377579
68365641	68365664	11	+	27383988	293T	resistance to West Nile virus (flavivirus)	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-1.4008852713059596	[403,403]	[0,0]	-8	hSpCas9	positive selection	3377580
68347872	68347895	11	-	26780180	HT29	viability (Avana library 4 designs)	CCACCAGCCGTACGTCCCGGCGG	LRP5	ENSG00000162337	0.606509966422165	[]	[]	2	hSpCas9	negative selection	3437573
68348019	68348042	11	+	26780180	HT29	viability (Avana library 4 designs)	GCAGACCTACCTGAACCAGACGG	LRP5	ENSG00000162337	0.0214046134505363	[]	[]	0	hSpCas9	negative selection	3437574
68410092	68410115	11	+	26780180	HT29	viability (Avana library 4 designs)	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	1.10483935946996	[]	[]	4	hSpCas9	negative selection	3437575
68409964	68409987	11	+	26780180	HT29	viability (Avana library 4 designs)	GTTTGGCCTTGACTACCCCGAGG	LRP5	ENSG00000162337	0.146727322188684	[]	[]	0	hSpCas9	negative selection	3437576
68347872	68347895	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCACCAGCCGTACGTCCCGGCGG	LRP5	ENSG00000162337	3.42177203793091	[]	[]	5	hSpCas9	negative selection	3526361
68348019	68348042	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGACCTACCTGAACCAGACGG	LRP5	ENSG00000162337	0.00387721846494876	[]	[]	0	hSpCas9	negative selection	3526362
68410092	68410115	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	3.93808359428012	[]	[]	6	hSpCas9	negative selection	3526363
68409964	68409987	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTTTGGCCTTGACTACCCCGAGG	LRP5	ENSG00000162337	4.31692004612587	[]	[]	7	hSpCas9	negative selection	3526364
68347952	68347975	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.290266598894708	[]	[]	0	hSpCas9	negative selection	3526365
68365641	68365664	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.887350861962184	[]	[]	-1	hSpCas9	negative selection	3526366
68347872	68347895	11	-	26780180	A375	viability (Avana lentiGuide)	CCACCAGCCGTACGTCCCGGCGG	LRP5	ENSG00000162337	-1.68154244813165	[]	[]	-3	hSpCas9	negative selection	3635020
68348019	68348042	11	+	26780180	A375	viability (Avana lentiGuide)	GCAGACCTACCTGAACCAGACGG	LRP5	ENSG00000162337	-1.722851349356	[]	[]	-3	hSpCas9	negative selection	3635021
68410092	68410115	11	+	26780180	A375	viability (Avana lentiGuide)	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	1.70902007458098	[]	[]	2	hSpCas9	negative selection	3635022
68409964	68409987	11	+	26780180	A375	viability (Avana lentiGuide)	GTTTGGCCTTGACTACCCCGAGG	LRP5	ENSG00000162337	0.863822650576423	[]	[]	1	hSpCas9	negative selection	3635023
68347952	68347975	11	-	26780180	A375	viability (Avana lentiGuide)	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-1.73110577124398	[]	[]	-3	hSpCas9	negative selection	3635024
68365641	68365664	11	+	26780180	A375	viability (Avana lentiGuide)	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-2.33507253678713	[]	[]	-4	hSpCas9	negative selection	3635025
68347872	68347895	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCACCAGCCGTACGTCCCGGCGG	LRP5	ENSG00000162337	0.2271999797084873	[4]	[4,4]	6	hSpCas9	positive selection	3743679
68348019	68348042	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGACCTACCTGAACCAGACGG	LRP5	ENSG00000162337	-0.40734033706028855	[5]	[5,2]	-6	hSpCas9	positive selection	3743680
68410092	68410115	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	0.10002316941272724	[4]	[4,4]	2	hSpCas9	positive selection	3743681
68409964	68409987	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTTTGGCCTTGACTACCCCGAGG	LRP5	ENSG00000162337	0.2564846333352463	[4]	[5,5]	7	hSpCas9	positive selection	3743682
68347952	68347975	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.14214069014481143	[5]	[5,5]	4	hSpCas9	positive selection	3743683
68365641	68365664	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.07186809140093559	[4]	[3,3]	-1	hSpCas9	positive selection	3743684
68347872	68347895	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCACCAGCCGTACGTCCCGGCGG	LRP5	ENSG00000162337	0.23819678885031495	[5]	[5,5]	6	hSpCas9	positive selection	3852286
68348019	68348042	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGACCTACCTGAACCAGACGG	LRP5	ENSG00000162337	-0.12012487233520427	[6]	[5,4]	-2	hSpCas9	positive selection	3852287
68410092	68410115	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.7193185740276028	[4]	[2,1]	-7	hSpCas9	positive selection	3852288
68409964	68409987	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTTTGGCCTTGACTACCCCGAGG	LRP5	ENSG00000162337	-0.12824213446215654	[5]	[4,3]	-2	hSpCas9	positive selection	3852289
68347952	68347975	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-0.1149711001058734	[5]	[2,5]	-2	hSpCas9	positive selection	3852290
68365641	68365664	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	0.18600411438299386	[4]	[3,5]	4	hSpCas9	positive selection	3852291
68348221	68348244	11	+	26780180	A375	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	1.02990539897556	[]	[]	5	hSpCas9	negative selection	3957938
68386431	68386454	11	+	26780180	A375	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	1.44282926867781	[]	[]	8	hSpCas9	negative selection	3957939
68365627	68365650	11	-	26780180	A375	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	1.11355776083959	[]	[]	5	hSpCas9	negative selection	3957940
68365641	68365664	11	+	26780180	A375	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	1.24011047790234	[]	[]	6	hSpCas9	negative selection	3957941
68347879	68347902	11	+	26780180	A375	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	1.46871477080725	[]	[]	8	hSpCas9	negative selection	3957942
68386614	68386637	11	-	26780180	A375	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	1.05563425225739	[]	[]	5	hSpCas9	negative selection	3957943
68348221	68348244	11	+	26780180	HT29	viability (GeCKOv2 library)	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.549600958414263	[]	[]	-9	hSpCas9	negative selection	4065904
68386431	68386454	11	+	26780180	HT29	viability (GeCKOv2 library)	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	1.45390873555116	[]	[]	7	hSpCas9	negative selection	4065905
68365627	68365650	11	-	26780180	HT29	viability (GeCKOv2 library)	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.383489315564622	[]	[]	1	hSpCas9	negative selection	4065906
68365641	68365664	11	+	26780180	HT29	viability (GeCKOv2 library)	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	0.683107206068799	[]	[]	2	hSpCas9	negative selection	4065907
68347879	68347902	11	+	26780180	HT29	viability (GeCKOv2 library)	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	2.04677223587164	[]	[]	9	hSpCas9	negative selection	4065908
68386614	68386637	11	-	26780180	HT29	viability (GeCKOv2 library)	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	1.14841487712171	[]	[]	5	hSpCas9	negative selection	4065909
68365627	68365650	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.3196300332010745	[3]	[0,2]	-7	hSpCas9	positive selection	4149332
68347875	68347898	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGTCCACCAGCCGTACGTCCCGG	LRP5	ENSG00000162337	-0.16031226404353413	[3]	[2,1]	-4	hSpCas9	positive selection	4149333
68347879	68347902	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.28207445213451554	[3]	[1,1]	-6	hSpCas9	positive selection	4149334
68365627	68365650	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.49570835004851727	[2]	[2,3,0,0]	3	hSpCas9	positive selection	4213354
68347875	68347898	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGTCCACCAGCCGTACGTCCCGG	LRP5	ENSG00000162337	0.3187007514103449	[3]	[0,3,3,0]	2	hSpCas9	positive selection	4213355
68347879	68347902	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.054453572173614795	[2]	[0,1,0,0]	0	hSpCas9	positive selection	4213356
68386431	68386454	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.003497458342273496	[3]	[2,1]	0	hSpCas9	positive selection	4280883
68347879	68347902	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.11657959397323939	[3]	[2,2]	2	hSpCas9	positive selection	4280884
68348221	68348244	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.16043724229561607	[4]	[4,3]	3	hSpCas9	positive selection	4280885
68386614	68386637	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.649317317938642	[2]	[1,0]	-9	hSpCas9	positive selection	4345142
68365627	68365650	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.025737127248942865	[2]	[2,1]	0	hSpCas9	positive selection	4345143
68365641	68365664	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.0051972699033237535	[4]	[4,2]	0	hSpCas9	positive selection	4345144
68347870	68347892	11	+	27760321	OCIAML3	viability	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	-0.2594688946490222	[434,297]	[236,235]	-3	hSpCas9	negative selection	4415154
68348086	68348108	11	+	27760321	OCIAML3	viability	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.09088623445378619	[875,751]	[731,602]	1	hSpCas9	negative selection	4415155
68386432	68386454	11	+	27760321	OCIAML3	viability	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.7258197319073421	[569,465]	[218,275]	-6	hSpCas9	negative selection	4415156
68406525	68406547	11	+	27760321	OCIAML3	viability	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.6614087288224011	[741,571]	[715,924]	7	hSpCas9	negative selection	4415157
68406727	68406749	11	+	27760321	OCIAML3	viability	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.4947067347643984	[891,697]	[709,1078]	6	hSpCas9	negative selection	4415158
68347870	68347892	11	+	27760321	OCIAML2	viability	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	-0.05478247125636593	[434,297]	[240,335]	0	hSpCas9	negative selection	4498617
68348086	68348108	11	+	27760321	OCIAML2	viability	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	-0.049307727348195995	[875,751]	[605,671]	0	hSpCas9	negative selection	4498618
68386432	68386454	11	+	27760321	OCIAML2	viability	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-1.3641201180571927	[569,465]	[164,157]	-8	hSpCas9	negative selection	4498619
68406525	68406547	11	+	27760321	OCIAML2	viability	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.5060451252183149	[741,571]	[690,825]	7	hSpCas9	negative selection	4498620
68406727	68406749	11	+	27760321	OCIAML2	viability	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.13919044925102764	[891,697]	[630,798]	1	hSpCas9	negative selection	4498621
68347870	68347892	11	+	27760321	MV411	viability	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	0.6947054097221145	[434,297]	[546,145]	5	hSpCas9	negative selection	4582080
68348086	68348108	11	+	27760321	MV411	viability	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.967616971025206	[875,751]	[1474,404]	7	hSpCas9	negative selection	4582081
68386432	68386454	11	+	27760321	MV411	viability	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-1.121632849565631	[569,465]	[55,306]	-6	hSpCas9	negative selection	4582082
68406525	68406547	11	+	27760321	MV411	viability	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.6700298077204614	[741,571]	[649,736]	5	hSpCas9	negative selection	4582083
68406727	68406749	11	+	27760321	MV411	viability	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.40696001693742334	[891,697]	[337,1220]	3	hSpCas9	negative selection	4582084
68347870	68347892	11	+	27760321	HL60	viability	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	1.7360132494452951	[434,297]	[844,1133]	9	hSpCas9	negative selection	4665543
68348086	68348108	11	+	27760321	HL60	viability	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	-0.7042737007049898	[875,751]	[303,515]	-6	hSpCas9	negative selection	4665544
68386432	68386454	11	+	27760321	HL60	viability	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.5301585633528503	[569,465]	[359,218]	-5	hSpCas9	negative selection	4665545
68406525	68406547	11	+	27760321	HL60	viability	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.07351594193387834	[741,571]	[563,556]	0	hSpCas9	negative selection	4665546
68406727	68406749	11	+	27760321	HL60	viability	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.2985201479282663	[891,697]	[737,851]	3	hSpCas9	negative selection	4665547
68347870	68347892	11	+	27760321	HT1080	viability	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	-0.1252591248240133	[297,232]	[64,131]	0	hSpCas9	negative selection	4749006
68348086	68348108	11	+	27760321	HT1080	viability	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.08191082497533742	[751,586]	[298,263]	0	hSpCas9	negative selection	4749007
68386432	68386454	11	+	27760321	HT1080	viability	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.05846189738049762	[465,363]	[195,117]	0	hSpCas9	negative selection	4749008
68406525	68406547	11	+	27760321	HT1080	viability	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.9253443322575358	[571,446]	[395,373]	5	hSpCas9	negative selection	4749009
68406727	68406749	11	+	27760321	HT1080	viability	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.5981904656678061	[697,544]	[275,482]	3	hSpCas9	negative selection	4749010
68347870	68347892	11	+	27760321	HT29	viability after 7 days	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	-0.3241103038540402	[297,232]	[339,172,312]	-5	hSpCas9	negative selection	4832469
68348086	68348108	11	+	27760321	HT29	viability after 7 days	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.09815325034694866	[751,586]	[785,859,1091]	1	hSpCas9	negative selection	4832470
68386432	68386454	11	+	27760321	HT29	viability after 7 days	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.028659375026082262	[465,363]	[489,577,555]	0	hSpCas9	negative selection	4832471
68406525	68406547	11	+	27760321	HT29	viability after 7 days	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.4645061271005605	[571,446]	[770,932,984]	7	hSpCas9	negative selection	4832472
68406727	68406749	11	+	27760321	HT29	viability after 7 days	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.362039901365492	[697,544]	[1028,1027,1022]	5	hSpCas9	negative selection	4832473
68347870	68347892	11	+	27760321	HT29	viability after 25 days	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	-0.250865014383633	[297,232]	[266,335,149]	-3	hSpCas9	negative selection	4915932
68348086	68348108	11	+	27760321	HT29	viability after 25 days	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.25193352437730854	[751,586]	[732,1048,966]	2	hSpCas9	negative selection	4915933
68386432	68386454	11	+	27760321	HT29	viability after 25 days	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.14197506840867544	[465,363]	[508,495,569]	1	hSpCas9	negative selection	4915934
68406525	68406547	11	+	27760321	HT29	viability after 25 days	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.6491938720580263	[571,446]	[661,1007,1103]	7	hSpCas9	negative selection	4915935
68406727	68406749	11	+	27760321	HT29	viability after 25 days	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.47982318337778795	[697,544]	[802,825,1394]	5	hSpCas9	negative selection	4915936
68347870	68347892	11	+	27760321	HT29	viability after 22 days	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	-0.12165893551500534	[297,232]	[195,238,414]	-1	hSpCas9	negative selection	4999395
68348086	68348108	11	+	27760321	HT29	viability after 22 days	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.2051225029324354	[751,586]	[622,1162,897]	2	hSpCas9	negative selection	4999396
68386432	68386454	11	+	27760321	HT29	viability after 22 days	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.5033831194398674	[465,363]	[330,406,276]	-5	hSpCas9	negative selection	4999397
68406525	68406547	11	+	27760321	HT29	viability after 22 days	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.5260397076346223	[571,446]	[802,669,1074]	6	hSpCas9	negative selection	4999398
68406727	68406749	11	+	27760321	HT29	viability after 22 days	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.3267693735355022	[697,544]	[674,978,1056]	3	hSpCas9	negative selection	4999399
68347870	68347892	11	+	27760321	HT29	viability after 19 days	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	0.16896759732329764	[297,232]	[339,506,182]	1	hSpCas9	negative selection	5082858
68348086	68348108	11	+	27760321	HT29	viability after 19 days	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.0323996323938317	[751,586]	[665,820,846]	0	hSpCas9	negative selection	5082859
68386432	68386454	11	+	27760321	HT29	viability after 19 days	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.48707581338597694	[465,363]	[565,700,715]	5	hSpCas9	negative selection	5082860
68406525	68406547	11	+	27760321	HT29	viability after 19 days	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.5345974059750346	[571,446]	[1050,832,675]	5	hSpCas9	negative selection	5082861
68406727	68406749	11	+	27760321	HT29	viability after 19 days	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.8807169828274126	[697,544]	[1058,1761,1086]	8	hSpCas9	negative selection	5082862
68347870	68347892	11	+	27760321	HT29	viability after 16 days	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	0.4960350004608577	[297,232]	[346,382,520]	5	hSpCas9	negative selection	5166321
68348086	68348108	11	+	27760321	HT29	viability after 16 days	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.5344113809643144	[751,586]	[919,1080,1237]	6	hSpCas9	negative selection	5166322
68386432	68386454	11	+	27760321	HT29	viability after 16 days	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.389305197348821	[465,363]	[362,441,256]	-4	hSpCas9	negative selection	5166323
68406525	68406547	11	+	27760321	HT29	viability after 16 days	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.6215803287393901	[571,446]	[961,806,871]	7	hSpCas9	negative selection	5166324
68406727	68406749	11	+	27760321	HT29	viability after 16 days	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.4720899933034097	[697,544]	[1159,846,907]	5	hSpCas9	negative selection	5166325
68347870	68347892	11	+	27760321	HT29	viability after 13 days	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	0.37801830082243437	[297,232]	[348,587,271]	5	hSpCas9	negative selection	5249784
68348086	68348108	11	+	27760321	HT29	viability after 13 days	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	0.1305830963374114	[751,586]	[676,868,995]	1	hSpCas9	negative selection	5249785
68386432	68386454	11	+	27760321	HT29	viability after 13 days	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.2930788343231726	[465,363]	[348,540,294]	-4	hSpCas9	negative selection	5249786
68406525	68406547	11	+	27760321	HT29	viability after 13 days	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.5096764159965744	[571,446]	[882,858,785]	6	hSpCas9	negative selection	5249787
68406727	68406749	11	+	27760321	HT29	viability after 13 days	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.25552056839639636	[697,544]	[890,949,747]	3	hSpCas9	negative selection	5249788
68347870	68347892	11	+	27760321	HT29	viability after 10 days	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	0.1613364521586969	[297,232]	[307,534,275]	2	hSpCas9	negative selection	5333247
68348086	68348108	11	+	27760321	HT29	viability after 10 days	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	-0.01921545283983983	[751,586]	[791,870,812]	0	hSpCas9	negative selection	5333248
68386432	68386454	11	+	27760321	HT29	viability after 10 days	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.40188487139222523	[465,363]	[679,172,318]	-5	hSpCas9	negative selection	5333249
68406525	68406547	11	+	27760321	HT29	viability after 10 days	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.3686599778854859	[571,446]	[725,981,761]	5	hSpCas9	negative selection	5333250
68406727	68406749	11	+	27760321	HT29	viability after 10 days	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.5513224497678528	[697,544]	[768,1074,1555]	7	hSpCas9	negative selection	5333251
68347870	68347892	11	+	27760321	MOLM13	viability	AACCGCCGGGACGTACGGCTGG	LRP5	ENSG00000162337	0.06723818279194729	[434,297]	[179,242]	0	hSpCas9	negative selection	5416710
68348086	68348108	11	+	27760321	MOLM13	viability	GACGGCCTCGCCTGCGACTGGG	LRP5	ENSG00000162337	-0.4686199020510932	[875,751]	[338,323]	-3	hSpCas9	negative selection	5416711
68386432	68386454	11	+	27760321	MOLM13	viability	ATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.5687077860050529	[569,465]	[500,371]	4	hSpCas9	negative selection	5416712
68406525	68406547	11	+	27760321	MOLM13	viability	AACCAACCCGTGTGCGGACAGG	LRP5	ENSG00000162337	0.17985891159105427	[741,571]	[378,448]	1	hSpCas9	negative selection	5416713
68406727	68406749	11	+	27760321	MOLM13	viability	ATCCCGCTCACGGGCGTCAAGG	LRP5	ENSG00000162337	0.6867445906777366	[891,697]	[1044,437]	5	hSpCas9	negative selection	5416714
68312680	68312703	11	+	27661255	K562	viability	GAGCGCGGCGCGGGCCCGTCCGG	LRP5	ENSG00000162337	-0.027314767509227456	[868,924]	[765,647]	-1	dCas9-KRAB	negative selection	5490898
68313021	68313044	11	+	27661255	K562	viability	GCGTCCCGGGCTGGCGAGGAGGG	LRP5	ENSG00000162337	0.08917525055801145	[388,428]	[401,299]	3	dCas9-KRAB	negative selection	5490899
68313042	68313065	11	+	27661255	K562	viability	GGCGCCCGCTCCGCCAGGTGCGG	LRP5	ENSG00000162337	0.014410962807849537	[875,900]	[790,652]	0	dCas9-KRAB	negative selection	5490900
68312703	68312726	11	-	27661255	K562	viability	GCTGCCTCCATGTTGTCCGGCGG	LRP5	ENSG00000162337	0.03677232152150717	[668,558]	[514,495]	1	dCas9-KRAB	negative selection	5490901
68312984	68313007	11	-	27661255	K562	viability	GGGCCCGGGTGGGGAGACAAAGG	LRP5	ENSG00000162337	-1.0530697318861213	[469,603]	[194,214]	-8	dCas9-KRAB	negative selection	5490902
68386431	68386454	11	+	27260156	BXPC3	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.15495253751587157	[496]	[420,489,428,534]	-4	hSpCas9	negative selection	5553343
68347879	68347902	11	+	27260156	BXPC3	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.0408367109305966	[582]	[487,608,508,793]	-1	hSpCas9	negative selection	5553344
68348221	68348244	11	+	27260156	BXPC3	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.2223508455603347	[1688]	[1913,1919,2040,2419]	5	hSpCas9	negative selection	5553345
68386614	68386637	11	-	27260156	BXPC3	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.21069550029292183	[209]	[186,239,152,171]	-5	hSpCas9	negative selection	5617602
68365627	68365650	11	-	27260156	BXPC3	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.004857435904587454	[420]	[433,358,448,525]	0	hSpCas9	negative selection	5617603
68365641	68365664	11	+	27260156	BXPC3	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.3837891237129174	[1432]	[1227,1048,1135,1171]	-7	hSpCas9	negative selection	5617604
68386431	68386454	11	+	27260156	A673	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.4720002081669169	[496]	[603,394,358,380]	-8	hSpCas9	negative selection	5674594
68347879	68347902	11	+	27260156	A673	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.08262183809375623	[582]	[651,615,648,729]	-2	hSpCas9	negative selection	5674595
68348221	68348244	11	+	27260156	A673	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.13268120834159358	[1688]	[2427,2321,1978,2180]	3	hSpCas9	negative selection	5674596
68386614	68386637	11	-	27260156	A673	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.34722823565281735	[209]	[211,164,273,139]	-7	hSpCas9	negative selection	5738853
68365627	68365650	11	-	27260156	A673	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.08418593860686809	[420]	[634,512,486,518]	2	hSpCas9	negative selection	5738854
68365641	68365664	11	+	27260156	A673	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.2761414501245112	[1432]	[1456,1335,1292,1612]	-6	hSpCas9	negative selection	5738855
68386431	68386454	11	+	27260156	A375	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.6378449038132954	[496]	[362,527,411,226]	-7	hSpCas9	negative selection	5795845
68347879	68347902	11	+	27260156	A375	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.22355301344382222	[582]	[665,982,828,731]	3	hSpCas9	negative selection	5795846
68348221	68348244	11	+	27260156	A375	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.03044379857149604	[1688]	[2085,2211,1503,1953]	0	hSpCas9	negative selection	5795847
68386614	68386637	11	-	27260156	A375	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.7684050016581614	[209]	[158,114,111,180]	-7	hSpCas9	negative selection	5860104
68365627	68365650	11	-	27260156	A375	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.11690441669558507	[420]	[445,652,395,638]	1	hSpCas9	negative selection	5860105
68365641	68365664	11	+	27260156	A375	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.5084882036437297	[1432]	[1213,1414,1205,929]	-6	hSpCas9	negative selection	5860106
68386431	68386454	11	+	27260156	COLO741	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.5550845064759439	[496]	[361,469,455]	-8	hSpCas9	negative selection	5917096
68347879	68347902	11	+	27260156	COLO741	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.341403896500522	[582]	[766,501,513]	-6	hSpCas9	negative selection	5917097
68348221	68348244	11	+	27260156	COLO741	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.14253004214342546	[1688]	[2808,2230,2153]	3	hSpCas9	negative selection	5917098
68386614	68386637	11	-	27260156	COLO741	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.5033674213626933	[209]	[239,244,93]	-8	hSpCas9	negative selection	5981355
68365627	68365650	11	-	27260156	COLO741	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.1362108927699624	[420]	[504,577,392]	-3	hSpCas9	negative selection	5981356
68365641	68365664	11	+	27260156	COLO741	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.3742063879939097	[1432]	[1398,1524,1316]	-7	hSpCas9	negative selection	5981357
68386431	68386454	11	+	27260156	CAL120	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.9095714475278571	[496]	[338,318,330]	-8	hSpCas9	negative selection	6038347
68347879	68347902	11	+	27260156	CAL120	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.05960389946684869	[582]	[1016,635,655]	0	hSpCas9	negative selection	6038348
68348221	68348244	11	+	27260156	CAL120	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.30503151542448625	[1688]	[3674,2459,1829]	4	hSpCas9	negative selection	6038349
68386614	68386637	11	-	27260156	CAL120	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-1.3002742620739525	[209]	[142,83,96]	-9	hSpCas9	negative selection	6102606
68365627	68365650	11	-	27260156	CAL120	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.46342563181018376	[420]	[294,511,320]	-6	hSpCas9	negative selection	6102607
68365641	68365664	11	+	27260156	CAL120	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.5164297661011328	[1432]	[1338,1206,1207]	-6	hSpCas9	negative selection	6102608
68386431	68386454	11	+	27260156	CADOES1	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.8436750282491815	[496]	[255,175,291,307]	-9	hSpCas9	negative selection	6159598
68347879	68347902	11	+	27260156	CADOES1	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.17053679638836383	[582]	[543,303,533,546]	-3	hSpCas9	negative selection	6159599
68348221	68348244	11	+	27260156	CADOES1	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.19020199897993484	[1688]	[1256,1484,1436,1326]	-3	hSpCas9	negative selection	6159600
68386614	68386637	11	-	27260156	CADOES1	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.18514470919031956	[209]	[114,115,211,246]	-3	hSpCas9	negative selection	6223857
68365627	68365650	11	-	27260156	CADOES1	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.23804606631586928	[420]	[260,380,309,377]	-4	hSpCas9	negative selection	6223858
68365641	68365664	11	+	27260156	CADOES1	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.6576572489484125	[1432]	[734,837,952,853]	-8	hSpCas9	negative selection	6223859
68386431	68386454	11	+	27260156	EWS502	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.4942091658313807	[496]	[331,451,301,410]	-7	hSpCas9	negative selection	6280849
68347879	68347902	11	+	27260156	EWS502	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.1989869139416383	[582]	[462,364,570,784]	-4	hSpCas9	negative selection	6280850
68348221	68348244	11	+	27260156	EWS502	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.11420823417768355	[1688]	[1382,2144,2144,2140]	2	hSpCas9	negative selection	6280851
68386614	68386637	11	-	27260156	EWS502	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.4100703246426487	[209]	[140,131,177,226]	-6	hSpCas9	negative selection	6345108
68365627	68365650	11	-	27260156	EWS502	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.032805176431993766	[420]	[472,366,376,617]	0	hSpCas9	negative selection	6345109
68365641	68365664	11	+	27260156	EWS502	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.46841962592311037	[1432]	[977,1111,989,1332]	-7	hSpCas9	negative selection	6345110
68386431	68386454	11	+	27260156	EW8	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.6540377365415776	[496]	[175,267,346,207]	-8	hSpCas9	negative selection	6402100
68347879	68347902	11	+	27260156	EW8	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.2365930351738295	[582]	[497,359,283,490]	-4	hSpCas9	negative selection	6402101
68348221	68348244	11	+	27260156	EW8	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.09885252498308139	[1688]	[1517,1825,1140,1436]	1	hSpCas9	negative selection	6402102
68386614	68386637	11	-	27260156	EW8	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.5056887759750717	[209]	[92,154,163,56]	-7	hSpCas9	negative selection	6466359
68365627	68365650	11	-	27260156	EW8	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.36608393992437444	[420]	[261,274,245,277]	-6	hSpCas9	negative selection	6466360
68365641	68365664	11	+	27260156	EW8	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.6306548095606459	[1432]	[925,878,545,701]	-8	hSpCas9	negative selection	6466361
68386431	68386454	11	+	27260156	CORL105	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.4156031487312688	[496]	[457,392,453,443]	-6	hSpCas9	negative selection	6523351
68347879	68347902	11	+	27260156	CORL105	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.24595074277996026	[582]	[483,680,726,428]	-4	hSpCas9	negative selection	6523352
68348221	68348244	11	+	27260156	CORL105	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.0402547934722961	[1688]	[2019,2177,2192,1763]	0	hSpCas9	negative selection	6523353
68386614	68386637	11	-	27260156	CORL105	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.3811007917067808	[209]	[121,201,180,245]	-6	hSpCas9	negative selection	6587610
68365627	68365650	11	-	27260156	CORL105	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.6429184707370659	[420]	[276,384,328,270]	-8	hSpCas9	negative selection	6587611
68365641	68365664	11	+	27260156	CORL105	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.9375151003852904	[1432]	[833,679,1170,866]	-9	hSpCas9	negative selection	6587612
68386431	68386454	11	+	27260156	HS294T	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.08994845959781979	[496]	[267,227,146,159]	1	hSpCas9	negative selection	6644602
68347879	68347902	11	+	27260156	HS294T	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.2113936794616849	[582]	[130,229,167,265]	-3	hSpCas9	negative selection	6644603
68348221	68348244	11	+	27260156	HS294T	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.06377368334049516	[1688]	[510,550,792,661]	-1	hSpCas9	negative selection	6644604
68386614	68386637	11	-	27260156	HS294T	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-1.1717850129445833	[209]	[30,31,43,37]	-9	hSpCas9	negative selection	6708861
68365627	68365650	11	-	27260156	HS294T	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.17019002981636572	[420]	[130,107,110,247]	-2	hSpCas9	negative selection	6708862
68365641	68365664	11	+	27260156	HS294T	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.5337640864147466	[1432]	[231,397,479,443]	-6	hSpCas9	negative selection	6708863
68386431	68386454	11	+	27260156	HCC44	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.11786453572959744	[496]	[471,633,806,541]	1	hSpCas9	negative selection	6765853
68347879	68347902	11	+	27260156	HCC44	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.1953874016055665	[582]	[958,657,835,611]	3	hSpCas9	negative selection	6765854
68348221	68348244	11	+	27260156	HCC44	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.22306614063117447	[1688]	[2744,1563,2397,2359]	3	hSpCas9	negative selection	6765855
68386614	68386637	11	-	27260156	HCC44	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.3777051688936208	[209]	[158,196,185,183]	-5	hSpCas9	negative selection	6830112
68365627	68365650	11	-	27260156	HCC44	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.21390312618531232	[420]	[427,408,439,369]	-3	hSpCas9	negative selection	6830113
68365641	68365664	11	+	27260156	HCC44	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.16514592124314342	[1432]	[1835,1309,1301,1354]	-3	hSpCas9	negative selection	6830114
68386431	68386454	11	+	27260156	G402	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.9075677808534743	[496]	[600,445,135,163]	-8	hSpCas9	negative selection	6887104
68347879	68347902	11	+	27260156	G402	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.19045514784080253	[582]	[772,599,717,429]	-2	hSpCas9	negative selection	6887105
68348221	68348244	11	+	27260156	G402	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.23427754505999454	[1688]	[1701,2143,1719,1464]	-3	hSpCas9	negative selection	6887106
68386614	68386637	11	-	27260156	G402	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.8844677849917029	[209]	[199,113,128,119]	-8	hSpCas9	negative selection	6951363
68365627	68365650	11	-	27260156	G402	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.21421357137571861	[420]	[592,641,276,297]	-3	hSpCas9	negative selection	6951364
68365641	68365664	11	+	27260156	G402	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.6089675060894685	[1432]	[1248,1578,787,1011]	-6	hSpCas9	negative selection	6951365
68386431	68386454	11	+	27260156	L33	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.0532322521143357	[496]	[478,200,344,544]	1	hSpCas9	negative selection	7008355
68347879	68347902	11	+	27260156	L33	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.1712914224417627	[582]	[484,247,329,456]	-4	hSpCas9	negative selection	7008356
68348221	68348244	11	+	27260156	L33	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.2802067239153079	[1688]	[1832,805,1312,2317]	6	hSpCas9	negative selection	7008357
68386614	68386637	11	-	27260156	L33	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.7581011489287868	[209]	[66,56,69,179]	-9	hSpCas9	negative selection	7072614
68365627	68365650	11	-	27260156	L33	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.17317205992801443	[420]	[516,135,243,253]	-4	hSpCas9	negative selection	7072615
68365641	68365664	11	+	27260156	L33	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.1770404173270652	[1432]	[1309,431,933,1219]	-4	hSpCas9	negative selection	7072616
68386431	68386454	11	+	27260156	K562	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.7189611035307644	[496]	[403,367,121,200]	-7	hSpCas9	negative selection	7129606
68347879	68347902	11	+	27260156	K562	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.02762659234043785	[582]	[686,352,598,477]	0	hSpCas9	negative selection	7129607
68348221	68348244	11	+	27260156	K562	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.040897340459784104	[1688]	[1290,1414,1464,1615]	0	hSpCas9	negative selection	7129608
68386614	68386637	11	-	27260156	K562	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.7979166108522744	[209]	[200,173,46,26]	-7	hSpCas9	negative selection	7193865
68365627	68365650	11	-	27260156	K562	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.15633694211206076	[420]	[410,549,412,308]	2	hSpCas9	negative selection	7193866
68365641	68365664	11	+	27260156	K562	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.4074893553857173	[1432]	[1064,1028,1041,733]	-5	hSpCas9	negative selection	7193867
68386431	68386454	11	+	27260156	HT29	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.14885093176884517	[496]	[653,405,681,442]	-3	hSpCas9	negative selection	7250857
68347879	68347902	11	+	27260156	HT29	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.0806222483470177	[582]	[833,681,960,541]	1	hSpCas9	negative selection	7250858
68348221	68348244	11	+	27260156	HT29	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.22207298376359264	[1688]	[2662,2681,2090,2195]	4	hSpCas9	negative selection	7250859
68386614	68386637	11	-	27260156	HT29	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.5482308381451075	[209]	[206,152,201,139]	-7	hSpCas9	negative selection	7315116
68365627	68365650	11	-	27260156	HT29	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.06023079937243339	[420]	[406,643,482,438]	-1	hSpCas9	negative selection	7315117
68365641	68365664	11	+	27260156	HT29	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.24455689833952432	[1432]	[1438,1681,1389,1385]	-5	hSpCas9	negative selection	7315118
68386431	68386454	11	+	27260156	MHHES1	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.46822959605068304	[496]	[266,635,427,307]	-7	hSpCas9	negative selection	7372108
68347879	68347902	11	+	27260156	MHHES1	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.11596832426487999	[582]	[588,843,764,305]	-2	hSpCas9	negative selection	7372109
68348221	68348244	11	+	27260156	MHHES1	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.24341412867924528	[1688]	[1726,1513,1456,1678]	-4	hSpCas9	negative selection	7372110
68386614	68386637	11	-	27260156	MHHES1	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.734022400065937	[209]	[202,197,55,124]	-8	hSpCas9	negative selection	7436367
68365627	68365650	11	-	27260156	MHHES1	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.5054928391622768	[420]	[336,407,187,388]	-7	hSpCas9	negative selection	7436368
68365641	68365664	11	+	27260156	MHHES1	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.8106622480762206	[1432]	[1117,917,884,791]	-9	hSpCas9	negative selection	7436369
68386431	68386454	11	+	27260156	MEWO	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.5616400986760496	[496]	[369,249,335]	-8	hSpCas9	negative selection	7493359
68347879	68347902	11	+	27260156	MEWO	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.020777865813401408	[582]	[698,374,614]	0	hSpCas9	negative selection	7493360
68348221	68348244	11	+	27260156	MEWO	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.22499560195651558	[1688]	[2063,1686,1831]	5	hSpCas9	negative selection	7493361
68386614	68386637	11	-	27260156	MEWO	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.24484554740615438	[209]	[209,150,144]	-5	hSpCas9	negative selection	7557618
68365627	68365650	11	-	27260156	MEWO	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.12428335440582874	[420]	[587,340,389]	2	hSpCas9	negative selection	7557619
68365641	68365664	11	+	27260156	MEWO	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.2522748365979055	[1432]	[1173,1098,1112]	-5	hSpCas9	negative selection	7557620
68386431	68386454	11	+	27260156	LNCAPCLONEFGC	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.4921233199134852	[496]	[390,269,386,243]	-6	hSpCas9	negative selection	7614610
68347879	68347902	11	+	27260156	LNCAPCLONEFGC	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.019951990616709214	[582]	[553,571,570,446]	0	hSpCas9	negative selection	7614611
68348221	68348244	11	+	27260156	LNCAPCLONEFGC	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.00010856599466624317	[1688]	[1395,1296,2106,1422]	0	hSpCas9	negative selection	7614612
68386614	68386637	11	-	27260156	LNCAPCLONEFGC	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.7085889570475599	[209]	[131,137,83,104]	-8	hSpCas9	negative selection	7678869
68365627	68365650	11	-	27260156	LNCAPCLONEFGC	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.2927104461762386	[420]	[538,196,221,276]	-4	hSpCas9	negative selection	7678870
68365641	68365664	11	+	27260156	LNCAPCLONEFGC	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.8125737102970526	[1432]	[661,695,912,714]	-8	hSpCas9	negative selection	7678871
68386431	68386454	11	+	27260156	PANC0327	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.5833499485015592	[496]	[322,232,384,247]	-7	hSpCas9	negative selection	7735861
68347879	68347902	11	+	27260156	PANC0327	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.2592748695125013	[582]	[610,663,709,487]	4	hSpCas9	negative selection	7735862
68348221	68348244	11	+	27260156	PANC0327	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.18520417942808853	[1688]	[2097,1300,1574,1932]	2	hSpCas9	negative selection	7735863
68386614	68386637	11	-	27260156	PANC0327	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.6495562560914296	[209]	[148,165,85,70]	-7	hSpCas9	negative selection	7800120
68365627	68365650	11	-	27260156	PANC0327	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.07809406680674513	[420]	[378,297,249,498]	-1	hSpCas9	negative selection	7800121
68365641	68365664	11	+	27260156	PANC0327	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.9856072471899153	[1432]	[667,448,566,913]	-8	hSpCas9	negative selection	7800122
68386431	68386454	11	+	27260156	NCIH2009	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.007834639924729214	[496]	[793,532,766]	0	hSpCas9	negative selection	7857112
68347879	68347902	11	+	27260156	NCIH2009	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.31091751101572734	[582]	[1389,713,1005]	4	hSpCas9	negative selection	7857113
68348221	68348244	11	+	27260156	NCIH2009	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.3798567613419892	[1688]	[3709,2627,3002]	5	hSpCas9	negative selection	7857114
68386614	68386637	11	-	27260156	NCIH2009	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.6450678845280211	[209]	[145,204,202]	-7	hSpCas9	negative selection	7921371
68365627	68365650	11	-	27260156	NCIH2009	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.45739418849576047	[420]	[575,296,442]	-5	hSpCas9	negative selection	7921372
68365641	68365664	11	+	27260156	NCIH2009	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.542366534140089	[1432]	[1858,1353,1004]	-6	hSpCas9	negative selection	7921373
68386431	68386454	11	+	27260156	NCIH1373	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.6339286313213154	[496]	[351,474,314,71]	-6	hSpCas9	negative selection	7978363
68347879	68347902	11	+	27260156	NCIH1373	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.04605617346333046	[582]	[528,684,498,211]	0	hSpCas9	negative selection	7978364
68348221	68348244	11	+	27260156	NCIH1373	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.2404938540543764	[1688]	[1576,1668,1605,402]	-2	hSpCas9	negative selection	7978365
68386614	68386637	11	-	27260156	NCIH1373	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.8451779470709251	[209]	[311,41,36,45]	-7	hSpCas9	negative selection	8042622
68365627	68365650	11	-	27260156	NCIH1373	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.5503327741154247	[420]	[375,277,497,34]	-5	hSpCas9	negative selection	8042623
68365641	68365664	11	+	27260156	NCIH1373	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-1.3188981654829082	[1432]	[1013,475,345,217]	-8	hSpCas9	negative selection	8042624
68386431	68386454	11	+	27260156	PATU8902	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.5480505015484267	[496]	[357,286,682,512]	-5	hSpCas9	negative selection	8099614
68347879	68347902	11	+	27260156	PATU8902	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.1446408413524379	[582]	[379,708,801,1067]	-1	hSpCas9	negative selection	8099615
68348221	68348244	11	+	27260156	PATU8902	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.7091622547793468	[1688]	[1702,1093,1092,2006]	-6	hSpCas9	negative selection	8099616
68386614	68386637	11	-	27260156	PATU8902	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.6000610315534753	[209]	[267,135,109,287]	-5	hSpCas9	negative selection	8163873
68365627	68365650	11	-	27260156	PATU8902	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.4865857377348511	[420]	[441,619,315,305]	-5	hSpCas9	negative selection	8163874
68365641	68365664	11	+	27260156	PATU8902	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-2.0767143016739356	[1432]	[615,405,408,471]	-9	hSpCas9	negative selection	8163875
68386431	68386454	11	+	27260156	PANC1	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.4764092201901762	[496]	[344,405,224,270]	-6	hSpCas9	negative selection	8220865
68347879	68347902	11	+	27260156	PANC1	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.37463946973928564	[582]	[315,583,479,227]	-5	hSpCas9	negative selection	8220866
68348221	68348244	11	+	27260156	PANC1	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.08195696539570174	[1688]	[1218,1966,1215,1208]	-1	hSpCas9	negative selection	8220867
68386614	68386637	11	-	27260156	PANC1	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.8157998611165593	[209]	[54,80,177,92]	-8	hSpCas9	negative selection	8285124
68365627	68365650	11	-	27260156	PANC1	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.2239710538932438	[420]	[371,293,330,242]	-4	hSpCas9	negative selection	8285125
68365641	68365664	11	+	27260156	PANC1	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.6373989245875197	[1432]	[788,922,959,548]	-7	hSpCas9	negative selection	8285126
68386431	68386454	11	+	27260156	PANC0813	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.41952307282239915	[496]	[582,326,416,431]	-6	hSpCas9	negative selection	8342116
68347879	68347902	11	+	27260156	PANC0813	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.02200053728279827	[582]	[751,703,682,648]	0	hSpCas9	negative selection	8342117
68348221	68348244	11	+	27260156	PANC0813	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.2390960945347329	[1688]	[2666,2177,2428,2130]	4	hSpCas9	negative selection	8342118
68386614	68386637	11	-	27260156	PANC0813	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.8818251843143765	[209]	[177,120,102,136]	-8	hSpCas9	negative selection	8406375
68365627	68365650	11	-	27260156	PANC0813	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.5467108637934677	[420]	[402,288,353,314]	-7	hSpCas9	negative selection	8406376
68365641	68365664	11	+	27260156	PANC0813	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.8603069943913035	[1432]	[898,789,1028,983]	-8	hSpCas9	negative selection	8406377
68386431	68386454	11	+	27260156	RDES	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.8772438751417574	[496]	[254,254,243,529]	-9	hSpCas9	negative selection	8463367
68347879	68347902	11	+	27260156	RDES	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.16772049997123217	[582]	[479,570,726,628]	-3	hSpCas9	negative selection	8463368
68348221	68348244	11	+	27260156	RDES	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.4864238604227962	[1688]	[1017,1396,1392,1846]	-7	hSpCas9	negative selection	8463369
68386614	68386637	11	-	27260156	RDES	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.6336690072080908	[209]	[97,157,156,228]	-8	hSpCas9	negative selection	8527626
68365627	68365650	11	-	27260156	RDES	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.2701065018455152	[420]	[194,380,585,503]	-4	hSpCas9	negative selection	8527627
68365641	68365664	11	+	27260156	RDES	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.7712847244447998	[1432]	[861,922,1104,973]	-8	hSpCas9	negative selection	8527628
68386431	68386454	11	+	27260156	PC3	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.08158934823596702	[496]	[312,487,670,498]	-2	hSpCas9	negative selection	8584618
68347879	68347902	11	+	27260156	PC3	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.08946319730238461	[582]	[424,417,1104,752]	2	hSpCas9	negative selection	8584619
68348221	68348244	11	+	27260156	PC3	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.30798309785744316	[1688]	[1411,1813,3254,2419]	6	hSpCas9	negative selection	8584620
68386614	68386637	11	-	27260156	PC3	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.28115333079067906	[209]	[70,147,346,227]	-6	hSpCas9	negative selection	8648877
68365627	68365650	11	-	27260156	PC3	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.046452524258712796	[420]	[250,605,749,271]	1	hSpCas9	negative selection	8648878
68365641	68365664	11	+	27260156	PC3	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.17568365784285533	[1432]	[672,1241,2141,1507]	-4	hSpCas9	negative selection	8648879
68386431	68386454	11	+	27260156	PATU8988T	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	0.2023154916979537	[496]	[696,443,541,513]	3	hSpCas9	negative selection	8705869
68347879	68347902	11	+	27260156	PATU8988T	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.09858522026914857	[582]	[408,582,693,733]	1	hSpCas9	negative selection	8705870
68348221	68348244	11	+	27260156	PATU8988T	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.2463822156124178	[1688]	[1884,1762,1863,2240]	4	hSpCas9	negative selection	8705871
68386614	68386637	11	-	27260156	PATU8988T	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.8277736836680982	[209]	[36,113,221,79]	-8	hSpCas9	negative selection	8770128
68365627	68365650	11	-	27260156	PATU8988T	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.10587775688836495	[420]	[438,346,492,464]	1	hSpCas9	negative selection	8770129
68365641	68365664	11	+	27260156	PATU8988T	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	0.07858939801077347	[1432]	[1575,1423,1541,1287]	1	hSpCas9	negative selection	8770130
68386431	68386454	11	+	27260156	T47D	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.5799369903195787	[496]	[366,356,418,408]	-8	hSpCas9	negative selection	8827120
68347879	68347902	11	+	27260156	T47D	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.157386283365637	[582]	[600,571,639,625]	-4	hSpCas9	negative selection	8827121
68348221	68348244	11	+	27260156	T47D	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.006334687043193066	[1688]	[2143,1981,1855,1922]	0	hSpCas9	negative selection	8827122
68386614	68386637	11	-	27260156	T47D	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.667573296176259	[209]	[109,131,153,223]	-8	hSpCas9	negative selection	8891379
68365627	68365650	11	-	27260156	T47D	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.10558951880495976	[420]	[544,435,457,383]	-2	hSpCas9	negative selection	8891380
68365641	68365664	11	+	27260156	T47D	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.5128406964028356	[1432]	[1320,1043,1144,1181]	-8	hSpCas9	negative selection	8891381
68386431	68386454	11	+	27260156	SU8686	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.2655949696908146	[496]	[442,310,350,563]	-4	hSpCas9	negative selection	8948371
68347879	68347902	11	+	27260156	SU8686	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.10631684740676212	[582]	[551,540,776,639]	1	hSpCas9	negative selection	8948372
68348221	68348244	11	+	27260156	SU8686	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.26036920820226594	[1688]	[1932,1688,1879,2657]	4	hSpCas9	negative selection	8948373
68386614	68386637	11	-	27260156	SU8686	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.6630202030241119	[209]	[107,109,218,88]	-7	hSpCas9	negative selection	9012630
68365627	68365650	11	-	27260156	SU8686	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.36810566980681686	[420]	[253,302,321,441]	-6	hSpCas9	negative selection	9012631
68365641	68365664	11	+	27260156	SU8686	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.5517378087961085	[1432]	[814,893,1021,1205]	-7	hSpCas9	negative selection	9012632
68386431	68386454	11	+	27260156	SKES1	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.18160246567784577	[496]	[462,434,489,366]	-4	hSpCas9	negative selection	9069622
68347879	68347902	11	+	27260156	SKES1	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.035909173977144604	[582]	[807,520,511,562]	0	hSpCas9	negative selection	9069623
68348221	68348244	11	+	27260156	SKES1	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.11951936279805886	[1688]	[2164,2029,1750,1470]	2	hSpCas9	negative selection	9069624
68386614	68386637	11	-	27260156	SKES1	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.36981073897862204	[209]	[223,127,162,138]	-7	hSpCas9	negative selection	9133881
68365627	68365650	11	-	27260156	SKES1	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.335813564413005	[420]	[361,365,334,278]	-6	hSpCas9	negative selection	9133882
68365641	68365664	11	+	27260156	SKES1	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.20097931680263303	[1432]	[1343,1420,1409,864]	-4	hSpCas9	negative selection	9133883
68386431	68386454	11	+	27260156	TOV112D	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.2412602412983244	[496]	[326,524,340,505]	-5	hSpCas9	negative selection	9190873
68347879	68347902	11	+	27260156	TOV112D	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	0.20741039832317926	[582]	[344,1001,597,799]	4	hSpCas9	negative selection	9190874
68348221	68348244	11	+	27260156	TOV112D	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.07676851691843956	[1688]	[1779,2392,1512,1601]	1	hSpCas9	negative selection	9190875
68386614	68386637	11	-	27260156	TOV112D	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.868220525534728	[209]	[97,92,46,212]	-9	hSpCas9	negative selection	9255132
68365627	68365650	11	-	27260156	TOV112D	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	0.0653655151340255	[420]	[564,568,341,332]	1	hSpCas9	negative selection	9255133
68365641	68365664	11	+	27260156	TOV112D	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.6220102776138917	[1432]	[1160,1221,751,690]	-8	hSpCas9	negative selection	9255134
68386431	68386454	11	+	27260156	TC71	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.40712141568017507	[496]	[410,274,376,553]	-8	hSpCas9	negative selection	9312124
68347879	68347902	11	+	27260156	TC71	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.2773356422318619	[582]	[482,595,437,550]	-6	hSpCas9	negative selection	9312125
68348221	68348244	11	+	27260156	TC71	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	0.30666004441083894	[1688]	[2297,2140,2161,2364]	7	hSpCas9	negative selection	9312126
68386614	68386637	11	-	27260156	TC71	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.22826504568567163	[209]	[167,150,226,223]	-6	hSpCas9	negative selection	9376383
68365627	68365650	11	-	27260156	TC71	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.2642155932863563	[420]	[386,369,329,419]	-6	hSpCas9	negative selection	9376384
68365641	68365664	11	+	27260156	TC71	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.10918398468979595	[1432]	[1466,1546,1249,1437]	-3	hSpCas9	negative selection	9376385
68386431	68386454	11	+	27260156	TC32	viability	CATCGACTACGACCCGCTAGAGG	LRP5	ENSG00000162337	-0.2873204517777293	[496]	[383,344,408,386]	-5	hSpCas9	negative selection	9433375
68347879	68347902	11	+	27260156	TC32	viability	GACGTACGGCTGGTGGACGCCGG	LRP5	ENSG00000162337	-0.0007545810011302945	[582]	[502,287,776,747]	0	hSpCas9	negative selection	9433376
68348221	68348244	11	+	27260156	TC32	viability	ATCGCCTTGGACCCCGCTCACGG	LRP5	ENSG00000162337	-0.018392879522566075	[1688]	[1370,1159,1962,1951]	0	hSpCas9	negative selection	9433377
68386614	68386637	11	-	27260156	TC32	viability	TGAGGCGCGTCACCTCGATGCGG	LRP5	ENSG00000162337	-0.26574783811729663	[209]	[162,75,226,229]	-5	hSpCas9	negative selection	9497634
68365627	68365650	11	-	27260156	TC32	viability	CATGTGTAGAAAGGCTCGCTTGG	LRP5	ENSG00000162337	-0.10432457419810781	[420]	[356,244,485,434]	-2	hSpCas9	negative selection	9497635
68365641	68365664	11	+	27260156	TC32	viability	CTACACATGCGCCTGCCCCACGG	LRP5	ENSG00000162337	-0.7129822254024494	[1432]	[663,538,1265,984]	-8	hSpCas9	negative selection	9497636
68348163	68348186	11	+	27869803	HPAFII	viability after 27 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-2.7563451082433295	[228]	[37,0,NaN]	-9	hSpCas9	negative selection	9543673
68357683	68357706	11	+	27869803	HPAFII	viability after 27 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-3.4900309885669665	[407]	[11,24,NaN]	-9	hSpCas9	negative selection	9543674
68363840	68363863	11	-	27869803	HPAFII	viability after 27 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.668039258580006	[269]	[200,245,NaN]	5	hSpCas9	negative selection	9543675
68365636	68365659	11	-	27869803	HPAFII	viability after 27 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	-0.549998510971853	[359]	[197,71,NaN]	-4	hSpCas9	negative selection	9543676
68386584	68386607	11	+	27869803	HPAFII	viability after 27 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.11464283878193471	[152]	[25,137,NaN]	0	hSpCas9	negative selection	9543677
68403487	68403510	11	+	27869803	HPAFII	viability after 27 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-2.0612721014986652	[292]	[67,10,NaN]	-8	hSpCas9	negative selection	9543681
68348163	68348186	11	+	27869803	HPAFII	viability after 15 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.5889559514593515	[228]	[392,20,NaN]	-6	hSpCas9	negative selection	9626122
68357683	68357706	11	+	27869803	HPAFII	viability after 15 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.9603997391682129	[407]	[360,140,NaN]	-7	hSpCas9	negative selection	9626123
68363840	68363863	11	-	27869803	HPAFII	viability after 15 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.890317103714627	[269]	[720,423,NaN]	8	hSpCas9	negative selection	9626124
68365636	68365659	11	-	27869803	HPAFII	viability after 15 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	-0.206015546366565	[359]	[512,224,NaN]	-2	hSpCas9	negative selection	9626125
68386584	68386607	11	+	27869803	HPAFII	viability after 15 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.30465167225796747	[152]	[154,232,NaN]	3	hSpCas9	negative selection	9626126
68403487	68403510	11	+	27869803	HPAFII	viability after 15 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-1.1221835188319023	[292]	[275,62,NaN]	-8	hSpCas9	negative selection	9626130
68348163	68348186	11	+	27869803	ASPC1	viability after 36 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.4029869855754008	[453]	[160,116,91]	-4	hSpCas9	negative selection	9708571
68357683	68357706	11	+	27869803	ASPC1	viability after 36 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.7075076859508471	[1163]	[132,489,135]	-6	hSpCas9	negative selection	9708572
68363840	68363863	11	-	27869803	ASPC1	viability after 36 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.2773419484538904	[1053]	[225,278,727]	2	hSpCas9	negative selection	9708573
68365636	68365659	11	-	27869803	ASPC1	viability after 36 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.8652796992888692	[853]	[906,561,266]	8	hSpCas9	negative selection	9708574
68386584	68386607	11	+	27869803	ASPC1	viability after 36 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.6309130518338159	[570]	[206,93,99]	-6	hSpCas9	negative selection	9708575
68403487	68403510	11	+	27869803	ASPC1	viability after 36 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-1.038816698141783	[855]	[118,111,188]	-7	hSpCas9	negative selection	9708579
68348163	68348186	11	+	27869803	PATU8988S	viability after 35 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.6335324052946849	[423]	[142,76,NaN]	-6	hSpCas9	negative selection	9791020
68357683	68357706	11	+	27869803	PATU8988S	viability after 35 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.26417318038781756	[913]	[314,297,NaN]	-3	hSpCas9	negative selection	9791021
68363840	68363863	11	-	27869803	PATU8988S	viability after 35 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.1675716161012183	[1040]	[427,513,NaN]	2	hSpCas9	negative selection	9791022
68365636	68365659	11	-	27869803	PATU8988S	viability after 35 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	-0.23313438747564819	[825]	[296,268,NaN]	-2	hSpCas9	negative selection	9791023
68386584	68386607	11	+	27869803	PATU8988S	viability after 35 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.01572168496448645	[371]	[135,166,NaN]	0	hSpCas9	negative selection	9791024
68403487	68403510	11	+	27869803	PATU8988S	viability after 35 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-1.143729132695446	[764]	[114,163,NaN]	-8	hSpCas9	negative selection	9791028
68348163	68348186	11	+	27869803	PATU8988S	viability after 31 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-0.06257289483846473	[423]	[215,92,NaN]	0	hSpCas9	negative selection	9873469
68357683	68357706	11	+	27869803	PATU8988S	viability after 31 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-0.15340820497009033	[913]	[361,283,NaN]	-2	hSpCas9	negative selection	9873470
68363840	68363863	11	-	27869803	PATU8988S	viability after 31 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.42442254315153927	[1040]	[304,877,NaN]	5	hSpCas9	negative selection	9873471
68365636	68365659	11	-	27869803	PATU8988S	viability after 31 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	0.1515164149106063	[825]	[338,399,NaN]	2	hSpCas9	negative selection	9873472
68386584	68386607	11	+	27869803	PATU8988S	viability after 31 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.1902382537279656	[371]	[170,166,NaN]	2	hSpCas9	negative selection	9873473
68403487	68403510	11	+	27869803	PATU8988S	viability after 31 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-0.6953047266345362	[764]	[117,277,NaN]	-6	hSpCas9	negative selection	9873477
68348163	68348186	11	+	27869803	HPAFII	viability after 35 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-2.888824094827607	[228]	[25,3,NaN]	-8	hSpCas9	negative selection	9955918
68357683	68357706	11	+	27869803	HPAFII	viability after 35 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-3.1056119058183764	[407]	[15,32,NaN]	-8	hSpCas9	negative selection	9955919
68363840	68363863	11	-	27869803	HPAFII	viability after 35 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.8110226301497933	[269]	[212,269,NaN]	5	hSpCas9	negative selection	9955920
68365636	68365659	11	-	27869803	HPAFII	viability after 35 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	-1.0833008830894357	[359]	[109,58,NaN]	-6	hSpCas9	negative selection	9955921
68386584	68386607	11	+	27869803	HPAFII	viability after 35 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	-0.2770823761185919	[152]	[22,109,NaN]	-2	hSpCas9	negative selection	9955922
68403487	68403510	11	+	27869803	HPAFII	viability after 35 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-2.228435617283889	[292]	[41,19,NaN]	-8	hSpCas9	negative selection	9955926
68348163	68348186	11	+	27869803	HPAFII	viability after 31 days	CCTCAATGGCACATCCCGGAAGG	LRP5	ENSG00000162337	-1.5217865509955988	[228]	[83,1,NaN]	-7	hSpCas9	negative selection	10038367
68357683	68357706	11	+	27869803	HPAFII	viability after 31 days	CCGGATTGAGCGGGCAGGGATGG	LRP5	ENSG00000162337	-2.9511807728580917	[407]	[31,26,NaN]	-8	hSpCas9	negative selection	10038368
68363840	68363863	11	-	27869803	HPAFII	viability after 31 days	CAGTGCGCTTGTTGCAGGCATGG	LRP5	ENSG00000162337	0.7053816867797932	[269]	[192,305,NaN]	5	hSpCas9	negative selection	10038369
68365636	68365659	11	-	27869803	HPAFII	viability after 31 days	GGGCAGGCGCATGTGTAGAAAGG	LRP5	ENSG00000162337	-0.9539853535997249	[359]	[121,84,NaN]	-6	hSpCas9	negative selection	10038370
68386584	68386607	11	+	27869803	HPAFII	viability after 31 days	AAACCTCTACTGGACCGACACGG	LRP5	ENSG00000162337	0.2477013221118402	[152]	[44,163,NaN]	1	hSpCas9	negative selection	10038371
68403487	68403510	11	+	27869803	HPAFII	viability after 31 days	TCAATGTTGATGGGACGAAGAGG	LRP5	ENSG00000162337	-1.5945255109174457	[292]	[97,6,NaN]	-7	hSpCas9	negative selection	10038375
68347882	68347905	11	+	28162770	P31FUJ	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.10423278286319215	[56]	[71]	1	hSpCas9	negative selection	10185843
68403490	68403513	11	+	28162770	P31FUJ	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.06764616306253221	[202]	[249]	0	hSpCas9	negative selection	10185844
68403503	68403526	11	+	28162770	P31FUJ	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-1.3272370062724277	[362]	[169]	-7	hSpCas9	negative selection	10185845
68410092	68410115	11	+	28162770	P31FUJ	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.3505241632874734	[267]	[246]	-3	hSpCas9	negative selection	10185846
68347952	68347975	11	-	28162770	P31FUJ	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.901053542320412	[35]	[78]	9	hSpCas9	negative selection	10185847
68347986	68348009	11	+	28162770	P31FUJ	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.9490108752262743	[375]	[852]	9	hSpCas9	negative selection	10185848
68348136	68348159	11	+	28162770	P31FUJ	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-0.5933919196708461	[103]	[80]	-5	hSpCas9	negative selection	10185849
68348196	68348219	11	+	28162770	P31FUJ	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-0.10080665860438837	[166]	[182]	-1	hSpCas9	negative selection	10185850
68365658	68365681	11	-	28162770	P31FUJ	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.48264268393831744	[282]	[237]	-4	hSpCas9	negative selection	10185851
68386537	68386560	11	+	28162770	P31FUJ	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.13806171444396875	[441]	[471]	-1	hSpCas9	negative selection	10185852
68347882	68347905	11	+	28162770	TF1	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	NaN	[NaN]	[119]	1	hSpCas9	negative selection	10355209
68403490	68403513	11	+	28162770	TF1	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	NaN	[NaN]	[234]	1	hSpCas9	negative selection	10355210
68403503	68403526	11	+	28162770	TF1	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10355211
68410092	68410115	11	+	28162770	TF1	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	NaN	[NaN]	[64]	1	hSpCas9	negative selection	10355212
68347952	68347975	11	-	28162770	TF1	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	NaN	[NaN]	[24]	1	hSpCas9	negative selection	10355213
68347986	68348009	11	+	28162770	TF1	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	NaN	[NaN]	[429]	1	hSpCas9	negative selection	10355214
68348136	68348159	11	+	28162770	TF1	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	NaN	[NaN]	[80]	1	hSpCas9	negative selection	10355215
68348196	68348219	11	+	28162770	TF1	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10355216
68365658	68365681	11	-	28162770	TF1	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	NaN	[NaN]	[20]	1	hSpCas9	negative selection	10355217
68386537	68386560	11	+	28162770	TF1	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	NaN	[NaN]	[415]	1	hSpCas9	negative selection	10355218
68347882	68347905	11	+	28162770	SKM1	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	-0.16992500144231237	[20]	[32]	-1	hSpCas9	negative selection	10524575
68403490	68403513	11	+	28162770	SKM1	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.4603980326787194	[36]	[89]	4	hSpCas9	negative selection	10524576
68403503	68403526	11	+	28162770	SKM1	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.3091889830566845	[81]	[116]	-3	hSpCas9	negative selection	10524577
68410092	68410115	11	+	28162770	SKM1	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	0.3025433999162979	[60]	[132]	3	hSpCas9	negative selection	10524578
68347952	68347975	11	-	28162770	SKM1	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	1.9853532240355987	[7]	[55]	9	hSpCas9	negative selection	10524579
68347986	68348009	11	+	28162770	SKM1	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.5574500979863326	[117]	[306]	5	hSpCas9	negative selection	10524580
68348136	68348159	11	+	28162770	SKM1	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	0.01198835053906544	[22]	[40]	0	hSpCas9	negative selection	10524581
68348196	68348219	11	+	28162770	SKM1	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-1.2005133212757353	[38]	[29]	-7	hSpCas9	negative selection	10524582
68365658	68365681	11	-	28162770	SKM1	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.5740741845784199	[47]	[56]	-4	hSpCas9	negative selection	10524583
68386537	68386560	11	+	28162770	SKM1	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.012523604071431493	[96]	[169]	0	hSpCas9	negative selection	10524584
68347882	68347905	11	+	28162770	SKM1	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	-0.16992500144231237	[20]	[32]	-1	hSpCas9	negative selection	10693941
68403490	68403513	11	+	28162770	SKM1	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.4603980326787194	[36]	[89]	4	hSpCas9	negative selection	10693942
68403503	68403526	11	+	28162770	SKM1	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.3091889830566845	[81]	[116]	-3	hSpCas9	negative selection	10693943
68410092	68410115	11	+	28162770	SKM1	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	0.3025433999162979	[60]	[132]	3	hSpCas9	negative selection	10693944
68347952	68347975	11	-	28162770	SKM1	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	1.9853532240355987	[7]	[55]	9	hSpCas9	negative selection	10693945
68347986	68348009	11	+	28162770	SKM1	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.5574500979863326	[117]	[306]	5	hSpCas9	negative selection	10693946
68348136	68348159	11	+	28162770	SKM1	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	0.01198835053906544	[22]	[40]	0	hSpCas9	negative selection	10693947
68348196	68348219	11	+	28162770	SKM1	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-1.2005133212757353	[38]	[29]	-7	hSpCas9	negative selection	10693948
68365658	68365681	11	-	28162770	SKM1	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.5740741845784199	[47]	[56]	-4	hSpCas9	negative selection	10693949
68386537	68386560	11	+	28162770	SKM1	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.012523604071431493	[96]	[169]	0	hSpCas9	negative selection	10693950
68347882	68347905	11	+	28162770	PL21	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.3256704965731789	[65]	[35]	3	hSpCas9	negative selection	10863307
68403490	68403513	11	+	28162770	PL21	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	-0.03689958281152922	[164]	[69]	0	hSpCas9	negative selection	10863308
68403503	68403526	11	+	28162770	PL21	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	0.059127304962246385	[246]	[111]	0	hSpCas9	negative selection	10863309
68410092	68410115	11	+	28162770	PL21	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.8970290445176781	[260]	[60]	-6	hSpCas9	negative selection	10863310
68347952	68347975	11	-	28162770	PL21	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-2.5003001036517727	[38]	[2]	-9	hSpCas9	negative selection	10863311
68347986	68348009	11	+	28162770	PL21	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	-0.005329503810659553	[564]	[244]	0	hSpCas9	negative selection	10863312
68348136	68348159	11	+	28162770	PL21	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	0.7005686049988085	[81]	[57]	6	hSpCas9	negative selection	10863313
68348196	68348219	11	+	28162770	PL21	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-0.398119708845294	[108]	[35]	-3	hSpCas9	negative selection	10863314
68365658	68365681	11	-	28162770	PL21	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.28951592613610866	[204]	[72]	-2	hSpCas9	negative selection	10863315
68386537	68386560	11	+	28162770	PL21	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	0.6888341554934728	[314]	[220]	6	hSpCas9	negative selection	10863316
68347882	68347905	11	+	28162770	P31FUJ	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.10423278286319215	[56]	[71]	1	hSpCas9	negative selection	11032673
68403490	68403513	11	+	28162770	P31FUJ	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.06764616306253221	[202]	[249]	0	hSpCas9	negative selection	11032674
68403503	68403526	11	+	28162770	P31FUJ	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-1.3272370062724277	[362]	[169]	-7	hSpCas9	negative selection	11032675
68410092	68410115	11	+	28162770	P31FUJ	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.3505241632874734	[267]	[246]	-3	hSpCas9	negative selection	11032676
68347952	68347975	11	-	28162770	P31FUJ	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.901053542320412	[35]	[78]	9	hSpCas9	negative selection	11032677
68347986	68348009	11	+	28162770	P31FUJ	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.9490108752262743	[375]	[852]	9	hSpCas9	negative selection	11032678
68348136	68348159	11	+	28162770	P31FUJ	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-0.5933919196708461	[103]	[80]	-5	hSpCas9	negative selection	11032679
68348196	68348219	11	+	28162770	P31FUJ	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-0.10080665860438837	[166]	[182]	-1	hSpCas9	negative selection	11032680
68365658	68365681	11	-	28162770	P31FUJ	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.48264268393831744	[282]	[237]	-4	hSpCas9	negative selection	11032681
68386537	68386560	11	+	28162770	P31FUJ	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.13806171444396875	[441]	[471]	-1	hSpCas9	negative selection	11032682
68347882	68347905	11	+	28162770	OCIAML5	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	1.0820454934795456	[27]	[106]	8	hSpCas9	negative selection	11202039
68403490	68403513	11	+	28162770	OCIAML5	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.16747361553164822	[109]	[222]	1	hSpCas9	negative selection	11202040
68403503	68403526	11	+	28162770	OCIAML5	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.96012631672145	[193]	[179]	-6	hSpCas9	negative selection	11202041
68410092	68410115	11	+	28162770	OCIAML5	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.22304889006490514	[85]	[132]	-2	hSpCas9	negative selection	11202042
68347952	68347975	11	-	28162770	OCIAML5	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	1.1072914446386575	[8]	[34]	8	hSpCas9	negative selection	11202043
68347986	68348009	11	+	28162770	OCIAML5	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.2849143319634	[250]	[551]	2	hSpCas9	negative selection	11202044
68348136	68348159	11	+	28162770	OCIAML5	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	0.5199022065229608	[33]	[87]	4	hSpCas9	negative selection	11202045
68348196	68348219	11	+	28162770	OCIAML5	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	0.29119048011623516	[90]	[200]	2	hSpCas9	negative selection	11202046
68365658	68365681	11	-	28162770	OCIAML5	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.6694751575855241	[125]	[142]	-4	hSpCas9	negative selection	11202047
68386537	68386560	11	+	28162770	OCIAML5	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.10092204152802897	[242]	[408]	0	hSpCas9	negative selection	11202048
68347882	68347905	11	+	28162770	EOL1	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	-0.06580205839574615	[148]	[74]	0	hSpCas9	negative selection	11371405
68403490	68403513	11	+	28162770	EOL1	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.15357328523942948	[185]	[108]	1	hSpCas9	negative selection	11371406
68403503	68403526	11	+	28162770	EOL1	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.34569240399611145	[561]	[232]	-3	hSpCas9	negative selection	11371407
68410092	68410115	11	+	28162770	EOL1	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.5348838470667627	[483]	[175]	-4	hSpCas9	negative selection	11371408
68347952	68347975	11	-	28162770	EOL1	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-0.225694864010078	[90]	[40]	-2	hSpCas9	negative selection	11371409
68347986	68348009	11	+	28162770	EOL1	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.13031797195956907	[847]	[488]	1	hSpCas9	negative selection	11371410
68348136	68348159	11	+	28162770	EOL1	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	1.2561692626617407	[88]	[111]	9	hSpCas9	negative selection	11371411
68348196	68348219	11	+	28162770	EOL1	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-0.10328643662619086	[156]	[76]	-1	hSpCas9	negative selection	11371412
68365658	68365681	11	-	28162770	EOL1	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	0.7267593903521791	[280]	[244]	6	hSpCas9	negative selection	11371413
68386537	68386560	11	+	28162770	EOL1	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	1.0361931273994434	[434]	[469]	8	hSpCas9	negative selection	11371414
68347882	68347905	11	+	28162770	MOLM13	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.7479973007373142	[83]	[101]	5	hSpCas9	negative selection	11540771
68403490	68403513	11	+	28162770	MOLM13	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	-0.3414270568463116	[183]	[104]	-2	hSpCas9	negative selection	11540772
68403503	68403526	11	+	28162770	MOLM13	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.6637546242658923	[343]	[156]	-4	hSpCas9	negative selection	11540773
68410092	68410115	11	+	28162770	MOLM13	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	0.09523048453628676	[245]	[189]	0	hSpCas9	negative selection	11540774
68347952	68347975	11	-	28162770	MOLM13	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-0.39780952674382997	[81]	[44]	-2	hSpCas9	negative selection	11540775
68347986	68348009	11	+	28162770	MOLM13	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	1.004360272528228	[594]	[862]	7	hSpCas9	negative selection	11540776
68348136	68348159	11	+	28162770	MOLM13	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-6.863027496570038	[160]	[0]	-9	hSpCas9	negative selection	11540777
68348196	68348219	11	+	28162770	MOLM13	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-0.7361245104770147	[181]	[78]	-4	hSpCas9	negative selection	11540778
68365658	68365681	11	-	28162770	MOLM13	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.07041168041245106	[288]	[198]	0	hSpCas9	negative selection	11540779
68386537	68386560	11	+	28162770	MOLM13	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.17826104943596066	[589]	[376]	-1	hSpCas9	negative selection	11540780
68347882	68347905	11	+	28162770	HEL	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.19843673821631835	[82]	[60]	1	hSpCas9	negative selection	11710137
68403490	68403513	11	+	28162770	HEL	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.18463261082962712	[135]	[98]	1	hSpCas9	negative selection	11710138
68403503	68403526	11	+	28162770	HEL	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.9974735292862615	[345]	[110]	-6	hSpCas9	negative selection	11710139
68410092	68410115	11	+	28162770	HEL	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.1028398924705572	[279]	[166]	0	hSpCas9	negative selection	11710140
68347952	68347975	11	-	28162770	HEL	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.9095253726952581	[63]	[76]	7	hSpCas9	negative selection	11710141
68347986	68348009	11	+	28162770	HEL	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.6374348001404297	[544]	[542]	5	hSpCas9	negative selection	11710142
68348136	68348159	11	+	28162770	HEL	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-1.0942267621658495	[99]	[29]	-6	hSpCas9	negative selection	11710143
68348196	68348219	11	+	28162770	HEL	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-1.6385472783896593	[174]	[35]	-7	hSpCas9	negative selection	11710144
68365658	68365681	11	-	28162770	HEL	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-1.1714697610983096	[210]	[59]	-6	hSpCas9	negative selection	11710145
68386537	68386560	11	+	28162770	HEL	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-1.102506239930416	[465]	[138]	-6	hSpCas9	negative selection	11710146
68347882	68347905	11	+	28162770	MV411	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.008650691195658755	[58]	[49]	0	hSpCas9	negative selection	11879503
68403490	68403513	11	+	28162770	MV411	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	-0.2859946492982988	[164]	[113]	-2	hSpCas9	negative selection	11879504
68403503	68403526	11	+	28162770	MV411	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-1.051802949396692	[346]	[140]	-6	hSpCas9	negative selection	11879505
68410092	68410115	11	+	28162770	MV411	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	0.01648311594290347	[168]	[143]	0	hSpCas9	negative selection	11879506
68347952	68347975	11	-	28162770	MV411	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-0.5155232519163755	[55]	[32]	-4	hSpCas9	negative selection	11879507
68347986	68348009	11	+	28162770	MV411	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.7787281185574675	[428]	[619]	7	hSpCas9	negative selection	11879508
68348136	68348159	11	+	28162770	MV411	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-0.16195338535492643	[84]	[63]	-1	hSpCas9	negative selection	11879509
68348196	68348219	11	+	28162770	MV411	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	0.6100076301674836	[104]	[134]	5	hSpCas9	negative selection	11879510
68365658	68365681	11	-	28162770	MV411	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.6923019243997502	[210]	[109]	-5	hSpCas9	negative selection	11879511
68386537	68386560	11	+	28162770	MV411	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.6030489077978727	[347]	[192]	-4	hSpCas9	negative selection	11879512
68347882	68347905	11	+	28162770	MONOMAC1	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.6239930118951267	[29]	[52]	6	hSpCas9	negative selection	12048869
68403490	68403513	11	+	28162770	MONOMAC1	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.39732435166385216	[101]	[153]	4	hSpCas9	negative selection	12048870
68403503	68403526	11	+	28162770	MONOMAC1	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-1.1060631870120634	[168]	[89]	-7	hSpCas9	negative selection	12048871
68410092	68410115	11	+	28162770	MONOMAC1	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	0.2992680338412058	[150]	[212]	3	hSpCas9	negative selection	12048872
68347952	68347975	11	-	28162770	MONOMAC1	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	-2.589354269838314	[20]	[3]	-9	hSpCas9	negative selection	12048873
68347986	68348009	11	+	28162770	MONOMAC1	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.18803083663981845	[303]	[396]	2	hSpCas9	negative selection	12048874
68348136	68348159	11	+	28162770	MONOMAC1	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-0.8559999292244869	[29]	[18]	-6	hSpCas9	negative selection	12048875
68348196	68348219	11	+	28162770	MONOMAC1	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	0.4688456490451699	[103]	[164]	4	hSpCas9	negative selection	12048876
68365658	68365681	11	-	28162770	MONOMAC1	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	0.2724484362416666	[129]	[179]	2	hSpCas9	negative selection	12048877
68386537	68386560	11	+	28162770	MONOMAC1	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	-0.16123612563170686	[198]	[203]	-1	hSpCas9	negative selection	12048878
68347882	68347905	11	+	28162770	OCIAML2	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	0.3159665366486455	[9]	[68]	3	hSpCas9	negative selection	12218235
68403490	68403513	11	+	28162770	OCIAML2	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	-0.5468654110692466	[33]	[128]	-4	hSpCas9	negative selection	12218236
68403503	68403526	11	+	28162770	OCIAML2	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	-0.5384452094697326	[48]	[186]	-4	hSpCas9	negative selection	12218237
68410092	68410115	11	+	28162770	OCIAML2	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.45627453226509107	[49]	[201]	-4	hSpCas9	negative selection	12218238
68347952	68347975	11	-	28162770	OCIAML2	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.14828000740233227	[6]	[42]	1	hSpCas9	negative selection	12218239
68347986	68348009	11	+	28162770	OCIAML2	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.5506806810032512	[83]	[681]	5	hSpCas9	negative selection	12218240
68348136	68348159	11	+	28162770	OCIAML2	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-2.16577524371374	[16]	[20]	-8	hSpCas9	negative selection	12218241
68348196	68348219	11	+	28162770	OCIAML2	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	-0.10139601557644229	[23]	[123]	-1	hSpCas9	negative selection	12218242
68365658	68365681	11	-	28162770	OCIAML2	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.5103760040349176	[45]	[178]	-4	hSpCas9	negative selection	12218243
68386537	68386560	11	+	28162770	OCIAML2	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	0.19233518748026812	[59]	[379]	1	hSpCas9	negative selection	12218244
68347882	68347905	11	+	28162770	OCIAML3	viability	GTACGGCTGGTGGACGCCGGCGG	LRP5	ENSG00000162337	-0.1789701410453195	[20]	[55]	-1	hSpCas9	negative selection	12387601
68403490	68403513	11	+	28162770	OCIAML3	viability	ATGTTGATGGGACGAAGAGGCGG	LRP5	ENSG00000162337	0.8526754855711459	[30]	[168]	7	hSpCas9	negative selection	12387602
68403503	68403526	11	+	28162770	OCIAML3	viability	GAAGAGGCGGACCCTCCTGGAGG	LRP5	ENSG00000162337	0.8871190494124532	[59]	[334]	7	hSpCas9	negative selection	12387603
68410092	68410115	11	+	28162770	OCIAML3	viability	GGAGGGACTTGGACAACCCGAGG	LRP5	ENSG00000162337	-0.2914448703037318	[74]	[184]	-2	hSpCas9	negative selection	12387604
68347952	68347975	11	-	28162770	OCIAML3	viability	GGAAAACTGGAAGTCCACTGCGG	LRP5	ENSG00000162337	0.7794507552032812	[10]	[56]	7	hSpCas9	negative selection	12387605
68347986	68348009	11	+	28162770	OCIAML3	viability	GTACTGGACAGACGTGAGCGAGG	LRP5	ENSG00000162337	0.5844414334246877	[149]	[678]	5	hSpCas9	negative selection	12387606
68348136	68348159	11	+	28162770	OCIAML3	viability	AGAGACCAACCGCATCGAGGTGG	LRP5	ENSG00000162337	-0.8321673775189278	[22]	[38]	-6	hSpCas9	negative selection	12387607
68348196	68348219	11	+	28162770	OCIAML3	viability	GCAGGACCTTGACCAGCCGAGGG	LRP5	ENSG00000162337	0.16272120866347306	[28]	[97]	1	hSpCas9	negative selection	12387608
68365658	68365681	11	-	28162770	OCIAML3	viability	GTCCTGCAGCTGCACACCCGTGG	LRP5	ENSG00000162337	-0.16025094369873005	[66]	[180]	-1	hSpCas9	negative selection	12387609
68386537	68386560	11	+	28162770	OCIAML3	viability	ACCGAGATCAACGACCCCGATGG	LRP5	ENSG00000162337	0.1329738652694209	[86]	[287]	1	hSpCas9	negative selection	12387610