Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4052
• Symbol:LTBP1
• Description:latent transforming growth factor beta binding protein 1

DataSource: http://genomecrispr.dkfz.de/#!/results/LTBP1

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
33275005	33275028	2	+	26472758	Jiyoye	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	3.7109561296829763	[7]	[78]	9	hSpCas9	negative selection	93847
33188767	33188790	2	-	26472758	Jiyoye	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	-0.03111747007327348	[270]	[199]	0	hSpCas9	negative selection	93848
33217610	33217633	2	-	26472758	Jiyoye	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.4357445337026443	[99]	[101]	3	hSpCas9	negative selection	93849
33262770	33262793	2	-	26472758	Jiyoye	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-0.3633427723713593	[115]	[67]	-3	hSpCas9	negative selection	93850
33263317	33263340	2	-	26472758	Jiyoye	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.07356548157087567	[154]	[122]	0	hSpCas9	negative selection	93851
33360714	33360737	2	+	26472758	Jiyoye	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.45226327103441144	[188]	[194]	3	hSpCas9	negative selection	93852
33389197	33389220	2	+	26472758	Jiyoye	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	1.194066201003762	[141]	[244]	7	hSpCas9	negative selection	93853
33134800	33134823	2	+	26472758	Jiyoye	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.58167311273801	[69]	[78]	4	hSpCas9	negative selection	93854
33134809	33134832	2	-	26472758	Jiyoye	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.49296072402474733	[292]	[156]	-4	hSpCas9	negative selection	93855
33186992	33187015	2	+	26472758	Jiyoye	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	3.5771003829481853	[0]	[8]	9	hSpCas9	negative selection	93856
33275005	33275028	2	+	26472758	KBM7	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	1.2091025271630493	[266,152]	[391,71]	9	hSpCas9	negative selection	284965
33188767	33188790	2	-	26472758	KBM7	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.40572900411862944	[1000,950]	[631,588]	4	hSpCas9	negative selection	284966
33217610	33217633	2	-	26472758	KBM7	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.5401696103395619	[234,128]	[114,126]	6	hSpCas9	negative selection	284967
33262770	33262793	2	-	26472758	KBM7	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	0.05911080445932515	[417,281]	[208,132]	0	hSpCas9	negative selection	284968
33263317	33263340	2	-	26472758	KBM7	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.5303221610790277	[545,377]	[376,248]	6	hSpCas9	negative selection	284969
33360714	33360737	2	+	26472758	KBM7	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	1.0325061425081055	[846,573]	[894,474]	9	hSpCas9	negative selection	284970
33389197	33389220	2	+	26472758	KBM7	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	-0.08255675164527321	[1113,1076]	[582,402]	-1	hSpCas9	negative selection	284971
33134800	33134823	2	+	26472758	KBM7	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.7534823113200448	[250,346]	[174,301]	8	hSpCas9	negative selection	284972
33134809	33134832	2	-	26472758	KBM7	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.464512217539416	[829,851]	[243,327]	-4	hSpCas9	negative selection	284973
33186992	33187015	2	+	26472758	KBM7	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	0.2964825343448134	[75,64]	[38,41]	3	hSpCas9	negative selection	284974
33275005	33275028	2	+	26472758	Raji	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.522421034652443	[83]	[27]	5	hSpCas9	negative selection	476083
33188767	33188790	2	-	26472758	Raji	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.3772231191125077	[563]	[169]	3	hSpCas9	negative selection	476084
33217610	33217633	2	-	26472758	Raji	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.5079214649573282	[99]	[32]	5	hSpCas9	negative selection	476085
33262770	33262793	2	-	26472758	Raji	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-0.3560169854666433	[181]	[32]	-3	hSpCas9	negative selection	476086
33263317	33263340	2	-	26472758	Raji	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.5727945571675627	[196]	[67]	5	hSpCas9	negative selection	476087
33360714	33360737	2	+	26472758	Raji	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	1.3000286133159953	[279]	[159]	9	hSpCas9	negative selection	476088
33389197	33389220	2	+	26472758	Raji	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.02420078426664629	[588]	[138]	0	hSpCas9	negative selection	476089
33134800	33134823	2	+	26472758	Raji	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	-0.2980295450168442	[248]	[46]	-2	hSpCas9	negative selection	476090
33134809	33134832	2	-	26472758	Raji	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.3780432917966424	[531]	[94]	-3	hSpCas9	negative selection	476091
33186992	33187015	2	+	26472758	Raji	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	-3.5930561827674934	[103]	[1]	-9	hSpCas9	negative selection	476092
33275005	33275028	2	+	26472758	K562	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	-0.29990178855736316	[104]	[71]	-2	hSpCas9	negative selection	667201
33188767	33188790	2	-	26472758	K562	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	-0.32753177918125354	[882]	[593]	-2	hSpCas9	negative selection	667202
33217610	33217633	2	-	26472758	K562	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	-0.29295431453644905	[163]	[112]	-2	hSpCas9	negative selection	667203
33262770	33262793	2	-	26472758	K562	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-0.3059706245072833	[267]	[182]	-2	hSpCas9	negative selection	667204
33263317	33263340	2	-	26472758	K562	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	1.2298774018450533	[348]	[690]	9	hSpCas9	negative selection	667205
33360714	33360737	2	+	26472758	K562	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.3510565169025752	[742]	[799]	2	hSpCas9	negative selection	667206
33389197	33389220	2	+	26472758	K562	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.44204324385395277	[939]	[1077]	3	hSpCas9	negative selection	667207
33134800	33134823	2	+	26472758	K562	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.6912649651759666	[313]	[427]	5	hSpCas9	negative selection	667208
33134809	33134832	2	-	26472758	K562	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-1.5488952559134608	[817]	[235]	-6	hSpCas9	negative selection	667209
33186992	33187015	2	+	26472758	K562	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	1.3188435687930016	[84]	[178]	9	hSpCas9	negative selection	667210
32947393	32947416	2	-	26627737	DLD1	viability	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.7064862922509934	[397]	[171,156,267]	7	hSpCas9	negative selection	811769
32948920	32948943	2	-	26627737	DLD1	viability	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	-0.5132544605136211	[786]	[135,263,127]	-5	hSpCas9	negative selection	811770
33020914	33020937	2	+	26627737	DLD1	viability	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.732289346234377	[735]	[300,429,412]	7	hSpCas9	negative selection	811771
33110612	33110635	2	+	26627737	DLD1	viability	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.9165587267685854	[204]	[73,128,154]	8	hSpCas9	negative selection	811772
33134775	33134798	2	-	26627737	DLD1	viability	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	-0.7613127809516934	[673]	[200,111,67]	-6	hSpCas9	negative selection	811773
33187050	33187073	2	+	26627737	DLD1	viability	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.04142163337219862	[1715]	[622,449,574]	0	hSpCas9	negative selection	811774
32947393	32947416	2	-	26627737	GBM cells	viability after 5 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.1515566748728837	[208]	[159,88]	2	hSpCas9	negative selection	894084
32948920	32948943	2	-	26627737	GBM cells	viability after 5 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.24404936093437324	[221]	[161,119]	4	hSpCas9	negative selection	894085
33020914	33020937	2	+	26627737	GBM cells	viability after 5 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.30962544876173936	[500]	[310,354]	5	hSpCas9	negative selection	894086
33110612	33110635	2	+	26627737	GBM cells	viability after 5 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.812740630751333	[112]	[29,38]	-8	hSpCas9	negative selection	894087
33134775	33134798	2	-	26627737	GBM cells	viability after 5 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.9586686174061088	[200]	[187,230]	9	hSpCas9	negative selection	894088
33187050	33187073	2	+	26627737	GBM cells	viability after 5 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.19871915887490776	[735]	[483,421]	3	hSpCas9	negative selection	894089
32947393	32947416	2	-	26627737	GBM cells	viability after 13 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.1648479553550647	[208]	[173,88]	2	hSpCas9	negative selection	976399
32948920	32948943	2	-	26627737	GBM cells	viability after 13 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.21348055422594495	[221]	[153,127]	2	hSpCas9	negative selection	976400
33020914	33020937	2	+	26627737	GBM cells	viability after 13 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.41959803883896996	[500]	[367,359]	5	hSpCas9	negative selection	976401
33110612	33110635	2	+	26627737	GBM cells	viability after 13 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.4396372303963083	[112]	[42,46]	-5	hSpCas9	negative selection	976402
33134775	33134798	2	-	26627737	GBM cells	viability after 13 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.8644206685188575	[200]	[197,198]	8	hSpCas9	negative selection	976403
33187050	33187073	2	+	26627737	GBM cells	viability after 13 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.41386348236531845	[735]	[713,383]	5	hSpCas9	negative selection	976404
32947393	32947416	2	-	26627737	GBM cells	viability after 21 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.4177348963275227	[208]	[84,84]	-4	hSpCas9	negative selection	1058714
32948920	32948943	2	-	26627737	GBM cells	viability after 21 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.19248214754850018	[221]	[141,133]	2	hSpCas9	negative selection	1058715
33020914	33020937	2	+	26627737	GBM cells	viability after 21 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.738715109107055	[500]	[484,425]	7	hSpCas9	negative selection	1058716
33110612	33110635	2	+	26627737	GBM cells	viability after 21 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.6148151358738227	[112]	[37,41]	-5	hSpCas9	negative selection	1058717
33134775	33134798	2	-	26627737	GBM cells	viability after 21 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.8328079534229218	[200]	[217,172]	8	hSpCas9	negative selection	1058718
33187050	33187073	2	+	26627737	GBM cells	viability after 21 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.11170726350331472	[735]	[477,389]	1	hSpCas9	negative selection	1058719
32947393	32947416	2	-	26627737	RPE1	viability after 9 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.6359450036024186	[1002]	[267,116]	-4	hSpCas9	negative selection	1141029
32948920	32948943	2	-	26627737	RPE1	viability after 9 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.38542588556393925	[882]	[254,497]	2	hSpCas9	negative selection	1141030
33020914	33020937	2	+	26627737	RPE1	viability after 9 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	1.1155776194598435	[1409]	[890,1040]	6	hSpCas9	negative selection	1141031
33110612	33110635	2	+	26627737	RPE1	viability after 9 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	1.2397709945389963	[157]	[56,193]	7	hSpCas9	negative selection	1141032
33134775	33134798	2	-	26627737	RPE1	viability after 9 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.7491368334188948	[726]	[468,270]	5	hSpCas9	negative selection	1141033
33187050	33187073	2	+	26627737	RPE1	viability after 9 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	-0.13704288759173622	[4469]	[921,1724]	-1	hSpCas9	negative selection	1141034
32947393	32947416	2	-	26627737	RPE1	viability after 12 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.7650054397591786	[1002]	[211,101]	-5	hSpCas9	negative selection	1223344
32948920	32948943	2	-	26627737	RPE1	viability after 12 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.09982415025549218	[882]	[227,281]	0	hSpCas9	negative selection	1223345
33020914	33020937	2	+	26627737	RPE1	viability after 12 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	1.0959519910197377	[1409]	[766,854]	6	hSpCas9	negative selection	1223346
33110612	33110635	2	+	26627737	RPE1	viability after 12 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.6547237929034961	[157]	[60,72]	4	hSpCas9	negative selection	1223347
33134775	33134798	2	-	26627737	RPE1	viability after 12 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.8335986534540587	[726]	[333,362]	5	hSpCas9	negative selection	1223348
33187050	33187073	2	+	26627737	RPE1	viability after 12 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	-0.28087139851970866	[4469]	[834,1150]	-2	hSpCas9	negative selection	1223349
32947393	32947416	2	-	26627737	RPE1	viability after 15 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.9005368762372837	[1002]	[236,69]	-5	hSpCas9	negative selection	1305659
32948920	32948943	2	-	26627737	RPE1	viability after 15 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	-0.0639271110635927	[882]	[128,344]	0	hSpCas9	negative selection	1305660
33020914	33020937	2	+	26627737	RPE1	viability after 15 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.9299875961206513	[1409]	[763,755]	5	hSpCas9	negative selection	1305661
33110612	33110635	2	+	26627737	RPE1	viability after 15 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.12137629373676617	[157]	[41,54]	0	hSpCas9	negative selection	1305662
33134775	33134798	2	-	26627737	RPE1	viability after 15 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	1.2586243036276754	[726]	[769,223]	7	hSpCas9	negative selection	1305663
33187050	33187073	2	+	26627737	RPE1	viability after 15 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	-0.08688157085155446	[4469]	[961,1410]	0	hSpCas9	negative selection	1305664
32947393	32947416	2	-	26627737	RPE1	viability after 18 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.8372410814814486	[1002]	[238,57]	-5	hSpCas9	negative selection	1387974
32948920	32948943	2	-	26627737	RPE1	viability after 18 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.8393115213936231	[882]	[494,352]	5	hSpCas9	negative selection	1387975
33020914	33020937	2	+	26627737	RPE1	viability after 18 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	1.0033964560923554	[1409]	[815,705]	6	hSpCas9	negative selection	1387976
33110612	33110635	2	+	26627737	RPE1	viability after 18 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	1.2761006886577033	[157]	[110,94]	7	hSpCas9	negative selection	1387977
33134775	33134798	2	-	26627737	RPE1	viability after 18 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	1.3765735977084614	[726]	[477,542]	7	hSpCas9	negative selection	1387978
33187050	33187073	2	+	26627737	RPE1	viability after 18 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.18447237679356743	[4469]	[1118,1639]	1	hSpCas9	negative selection	1387979
32947393	32947416	2	-	26627737	HeLa	viability after 8 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.18405036899928814	[367]	[245,14,181]	-2	hSpCas9	negative selection	1470289
32948920	32948943	2	-	26627737	HeLa	viability after 8 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	1.1189780170077783	[329]	[434,293,238]	8	hSpCas9	negative selection	1470290
33020914	33020937	2	+	26627737	HeLa	viability after 8 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.05782697090357902	[1000]	[401,406,533]	0	hSpCas9	negative selection	1470291
33110612	33110635	2	+	26627737	HeLa	viability after 8 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.27760692697742584	[174]	[156,83,52]	2	hSpCas9	negative selection	1470292
33134775	33134798	2	-	26627737	HeLa	viability after 8 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.4557395345226962	[461]	[185,413,211]	4	hSpCas9	negative selection	1470293
33187050	33187073	2	+	26627737	HeLa	viability after 8 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.10329173448971951	[1504]	[631,644,809]	1	hSpCas9	negative selection	1470294
32947393	32947416	2	-	26627737	HeLa	viability after 12 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.2100761246363211	[367]	[89,57,252]	-2	hSpCas9	negative selection	1552604
32948920	32948943	2	-	26627737	HeLa	viability after 12 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	1.5885972563258766	[329]	[692,180,388]	9	hSpCas9	negative selection	1552605
33020914	33020937	2	+	26627737	HeLa	viability after 12 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	-0.2582230938612935	[1000]	[342,388,300]	-2	hSpCas9	negative selection	1552606
33110612	33110635	2	+	26627737	HeLa	viability after 12 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.10905386328047251	[174]	[69,122,35]	1	hSpCas9	negative selection	1552607
33134775	33134798	2	-	26627737	HeLa	viability after 12 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.7963127624959314	[461]	[393,298,306]	6	hSpCas9	negative selection	1552608
33187050	33187073	2	+	26627737	HeLa	viability after 12 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.6035084606375911	[1504]	[848,871,1118]	5	hSpCas9	negative selection	1552609
32947393	32947416	2	-	26627737	HeLa	viability after 15 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.08020779902419592	[367]	[101,237,133]	0	hSpCas9	negative selection	1634919
32948920	32948943	2	-	26627737	HeLa	viability after 15 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	1.4455449122598756	[329]	[415,303,377]	8	hSpCas9	negative selection	1634920
33020914	33020937	2	+	26627737	HeLa	viability after 15 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	-0.23050194882139463	[1000]	[362,304,375]	-2	hSpCas9	negative selection	1634921
33110612	33110635	2	+	26627737	HeLa	viability after 15 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.48287430790862285	[174]	[45,55,50]	-4	hSpCas9	negative selection	1634922
33134775	33134798	2	-	26627737	HeLa	viability after 15 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.2011995214536291	[461]	[51,343,257]	1	hSpCas9	negative selection	1634923
33187050	33187073	2	+	26627737	HeLa	viability after 15 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.7403390676793122	[1504]	[1137,691,1256]	6	hSpCas9	negative selection	1634924
32947393	32947416	2	-	26627737	HeLa	viability after 18 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.09282111331267129	[367]	[75,190,133]	0	hSpCas9	negative selection	1717234
32948920	32948943	2	-	26627737	HeLa	viability after 18 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	1.4469663891502833	[329]	[289,238,377]	8	hSpCas9	negative selection	1717235
33020914	33020937	2	+	26627737	HeLa	viability after 18 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	-0.22028743743243617	[1000]	[243,257,375]	-2	hSpCas9	negative selection	1717236
33110612	33110635	2	+	26627737	HeLa	viability after 18 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.6035995919608215	[174]	[31,34,50]	-5	hSpCas9	negative selection	1717237
33134775	33134798	2	-	26627737	HeLa	viability after 18 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.19307156243450843	[461]	[25,292,257]	1	hSpCas9	negative selection	1717238
33187050	33187073	2	+	26627737	HeLa	viability after 18 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.7500480886521979	[1504]	[784,562,1256]	6	hSpCas9	negative selection	1717239
32947393	32947416	2	-	26627737	HCT116	viability after 6 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.8947007407419005	[1291]	[463,329]	5	hSpCas9	negative selection	1799549
32948920	32948943	2	-	26627737	HCT116	viability after 6 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.29202438759026694	[779]	[289,72]	1	hSpCas9	negative selection	1799550
33020914	33020937	2	+	26627737	HCT116	viability after 6 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.9277273262190491	[1240]	[432,336]	5	hSpCas9	negative selection	1799551
33110612	33110635	2	+	26627737	HCT116	viability after 6 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	3.4412381551229396	[71]	[33,171]	9	hSpCas9	negative selection	1799552
33134775	33134798	2	-	26627737	HCT116	viability after 6 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	-0.3443628067742841	[471]	[51,61]	-2	hSpCas9	negative selection	1799553
33187050	33187073	2	+	26627737	HCT116	viability after 6 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.8196976369474633	[2313]	[828,538]	4	hSpCas9	negative selection	1799554
32947393	32947416	2	-	26627737	HCT116	viability after 8 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.681560800088988	[235]	[194,182,246]	6	hSpCas9	negative selection	1881864
32948920	32948943	2	-	26627737	HCT116	viability after 8 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.5010141112274065	[285]	[216,230,220]	5	hSpCas9	negative selection	1881865
33020914	33020937	2	+	26627737	HCT116	viability after 8 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.5391403378934515	[518]	[491,335,419]	5	hSpCas9	negative selection	1881866
33110612	33110635	2	+	26627737	HCT116	viability after 8 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.27209775662168356	[167]	[102,95,31]	-3	hSpCas9	negative selection	1881867
33134775	33134798	2	-	26627737	HCT116	viability after 8 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.9808140454962322	[245]	[137,290,369]	8	hSpCas9	negative selection	1881868
33187050	33187073	2	+	26627737	HCT116	viability after 8 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.7445113174163172	[722]	[741,615,645]	7	hSpCas9	negative selection	1881869
32947393	32947416	2	-	26627737	HCT116	viability after 9 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.2149877923224538	[1291]	[337,264]	-1	hSpCas9	negative selection	1964179
32948920	32948943	2	-	26627737	HCT116	viability after 9 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	-0.7336477668141805	[779]	[160,96]	-5	hSpCas9	negative selection	1964180
33020914	33020937	2	+	26627737	HCT116	viability after 9 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	-0.3373871192853276	[1240]	[397,154]	-2	hSpCas9	negative selection	1964181
33110612	33110635	2	+	26627737	HCT116	viability after 9 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-1.0081421155241848	[71]	[8,9]	-6	hSpCas9	negative selection	1964182
33134775	33134798	2	-	26627737	HCT116	viability after 9 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	1.2755234711517152	[471]	[222,369]	8	hSpCas9	negative selection	1964183
33187050	33187073	2	+	26627737	HCT116	viability after 9 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	-0.30646522166534385	[2313]	[650,379]	-2	hSpCas9	negative selection	1964184
32947393	32947416	2	-	26627737	HCT116	viability after 12 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	1.3545855960651105	[235]	[465,217,251]	9	hSpCas9	negative selection	2046494
32948920	32948943	2	-	26627737	HCT116	viability after 12 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.15371400044769196	[285]	[171,159,168]	1	hSpCas9	negative selection	2046495
33020914	33020937	2	+	26627737	HCT116	viability after 12 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.7316231941673254	[518]	[457,359,537]	6	hSpCas9	negative selection	2046496
33110612	33110635	2	+	26627737	HCT116	viability after 12 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.037429887042619736	[167]	[113,99,55]	0	hSpCas9	negative selection	2046497
33134775	33134798	2	-	26627737	HCT116	viability after 12 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.6054772572572916	[245]	[118,158,317]	5	hSpCas9	negative selection	2046498
33187050	33187073	2	+	26627737	HCT116	viability after 12 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.9799118796447541	[722]	[912,755,564]	8	hSpCas9	negative selection	2046499
32947393	32947416	2	-	26627737	HCT116	viability after 15 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.37474496193065515	[235]	[175,72,276]	3	hSpCas9	negative selection	2128809
32948920	32948943	2	-	26627737	HCT116	viability after 15 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.11529801923979624	[285]	[201,183,150]	1	hSpCas9	negative selection	2128810
33020914	33020937	2	+	26627737	HCT116	viability after 15 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.6580548996734837	[518]	[498,406,507]	6	hSpCas9	negative selection	2128811
33110612	33110635	2	+	26627737	HCT116	viability after 15 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.2967852824488768	[167]	[148,82,12]	-3	hSpCas9	negative selection	2128812
33134775	33134798	2	-	26627737	HCT116	viability after 15 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	1.047217126818261	[245]	[290,396,188]	8	hSpCas9	negative selection	2128813
33187050	33187073	2	+	26627737	HCT116	viability after 15 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	1.039476923149892	[722]	[1076,772,738]	8	hSpCas9	negative selection	2128814
32947393	32947416	2	-	26627737	HCT116	viability after 18 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	1.4220963417482608	[235]	[387,136,407]	8	hSpCas9	negative selection	2211124
32948920	32948943	2	-	26627737	HCT116	viability after 18 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	-0.34636914949825737	[285]	[198,73,52]	-3	hSpCas9	negative selection	2211125
33020914	33020937	2	+	26627737	HCT116	viability after 18 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	1.2153724136475983	[518]	[489,490,781]	8	hSpCas9	negative selection	2211126
33110612	33110635	2	+	26627737	HCT116	viability after 18 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.4481329863855869	[167]	[228,82,17]	4	hSpCas9	negative selection	2211127
33134775	33134798	2	-	26627737	HCT116	viability after 18 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.8066668073471104	[245]	[168,258,191]	6	hSpCas9	negative selection	2211128
33187050	33187073	2	+	26627737	HCT116	viability after 18 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	1.3446313468116646	[722]	[983,908,762]	8	hSpCas9	negative selection	2211129
32971637	32971660	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TAAAGCCTACTTGATTGTGGTAG	LTBP1	ENSG00000049323	0.21088050493068639	[71,100]	[22,20]	1	dCas9-VP64	positive selection	2387003
33072364	33072387	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGATAGGCATGATTGAAGCATGG	LTBP1	ENSG00000049323	1.5659950476035691	[9,17]	[8,8]	6	dCas9-VP64	positive selection	2388554
33138932	33138955	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CACTGCAAGCTCCGCCTCCCGGG	LTBP1	ENSG00000049323	0.20407356943453547	[198,395]	[107,39]	1	dCas9-VP64	positive selection	2401872
33134427	33134450	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	ATTAAAGAGCCAACCCTGACAGG	LTBP1	ENSG00000049323	1.4747232635484606	[124,28]	[39,53]	5	dCas9-VP64	positive selection	2405178
33134404	33134427	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGATGTAATGCAAAGGGGTTGG	LTBP1	ENSG00000049323	0.6103023660175753	[127,14]	[12,34]	2	dCas9-VP64	positive selection	2405179
33134459	33134482	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGACAAAGAGCAATACCGAGG	LTBP1	ENSG00000049323	-0.5319891450336636	[135,24]	[10,12]	-3	dCas9-VP64	positive selection	2405180
32969049	32969072	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CACCTGTAATCCCAGCTACTTGG	LTBP1	ENSG00000049323	-0.8190110364213175	[438,580]	[39,87]	-4	dCas9-VP64	positive selection	2406471
33088204	33088227	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGCACTTTGGGAGGCCAAGGCGG	LTBP1	ENSG00000049323	0.21234444010885142	[57,122]	[21,23]	1	dCas9-VP64	positive selection	2422525
33319280	33319303	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCCAGCTACTCATGAGGCTGTGG	LTBP1	ENSG00000049323	-2.630283297450045	[595,43]	[15,4]	-9	dCas9-VP64	positive selection	2425439
33386922	33386945	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCAGGAGAATCGCTTGAACCTAG	LTBP1	ENSG00000049323	0.915813201608152	[93,47]	[29,27]	4	dCas9-VP64	positive selection	2442397
33305101	33305124	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAGGAGATCGAGACCATCTTAG	LTBP1	ENSG00000049323	-2.0034890161781562	[180,449]	[14,19]	-9	dCas9-VP64	positive selection	2449524
33140899	33140922	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAGGTGGGTGGATCACTTGGGG	LTBP1	ENSG00000049323	0.9269503688862448	[9,0]	[1,1]	4	dCas9-VP64	positive selection	2463117
32996429	32996452	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAACATATGAATTTTGGGAGAG	LTBP1	ENSG00000049323	-1.5570174406252941	[150,368]	[15,21]	-8	dCas9-VP64	positive selection	2463294
33368100	33368123	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGGCTGAGGCAGGAGAATAG	LTBP1	ENSG00000049323	1.7244712313844854	[32,17]	[27,7]	6	dCas9-VP64	positive selection	2468524
33356572	33356595	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	AGGAGGCTGAGGCAGGAGAATGG	LTBP1	ENSG00000049323	1.7244712313844854	[32,17]	[27,7]	6	dCas9-VP64	positive selection	2468622
33204670	33204693	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGAGGATCACTTGAGCCCGAG	LTBP1	ENSG00000049323	1.3448043646809227	[134,24]	[56,28]	5	dCas9-VP64	positive selection	2469767
32950322	32950345	2	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGGTGGGTGGATCACTTGAGG	LTBP1	ENSG00000049323	2.670757623225415	[8,4]	[14,3]	8	dCas9-VP64	positive selection	2471827
32947207	32947230	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	AGCTGCCGAGAGCCCGGGAAAGG	LTBP1	ENSG00000049323	4.222688476025051	[97,149]	[355,682]	9	dCas9-VP64	positive selection	2477731
32947185	32947208	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GCGGGAGGAGACCAAGTCGGTGG	LTBP1	ENSG00000049323	1.2117913330945966	[21,16]	[4,14]	5	dCas9-VP64	positive selection	2477732
32947119	32947142	2	-	25494202	A375	resistance to PLX-4720 (puromycin)	GGCCGATTGTGGCTGGGAGCAGG	LTBP1	ENSG00000049323	2.2887536111682243	[0,0]	[1,0]	7	dCas9-VP64	positive selection	2477733
32971637	32971660	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TAAAGCCTACTTGATTGTGGTAG	LTBP1	ENSG00000049323	5.968448024182357	[110,135]	[39,4866]	9	dCas9-VP64	positive selection	2482258
33072364	33072387	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGATAGGCATGATTGAAGCATGG	LTBP1	ENSG00000049323	-0.7575306100082144	[14,145]	[9,19]	-7	dCas9-VP64	positive selection	2483809
33138932	33138955	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CACTGCAAGCTCCGCCTCCCGGG	LTBP1	ENSG00000049323	4.4236004262517	[85,230]	[22,2123]	9	dCas9-VP64	positive selection	2497127
33134427	33134450	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	ATTAAAGAGCCAACCCTGACAGG	LTBP1	ENSG00000049323	0.22685806260331742	[233,372]	[65,161]	1	dCas9-VP64	positive selection	2500433
33134404	33134427	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGATGTAATGCAAAGGGGTTGG	LTBP1	ENSG00000049323	1.2846721877994023	[100,97]	[24,129]	7	dCas9-VP64	positive selection	2500434
33134459	33134482	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGACAAAGAGCAATACCGAGG	LTBP1	ENSG00000049323	-0.6546684788891816	[100,76]	[19,15]	-6	dCas9-VP64	positive selection	2500435
32969049	32969072	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CACCTGTAATCCCAGCTACTTGG	LTBP1	ENSG00000049323	0.2665454673496357	[718,321]	[136,269]	2	dCas9-VP64	positive selection	2501726
33088204	33088227	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGCACTTTGGGAGGCCAAGGCGG	LTBP1	ENSG00000049323	-0.9329704115466368	[100,219]	[26,25]	-8	dCas9-VP64	positive selection	2517780
33319280	33319303	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCCAGCTACTCATGAGGCTGTGG	LTBP1	ENSG00000049323	-0.13308533926697091	[158,117]	[51,29]	-1	dCas9-VP64	positive selection	2520694
33386922	33386945	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCAGGAGAATCGCTTGAACCTAG	LTBP1	ENSG00000049323	-0.3136691189391476	[37,20]	[8,5]	-3	dCas9-VP64	positive selection	2537652
33305101	33305124	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAGGAGATCGAGACCATCTTAG	LTBP1	ENSG00000049323	2.1771212462212475	[324,289]	[546,370]	8	dCas9-VP64	positive selection	2544779
33140899	33140922	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAGGTGGGTGGATCACTTGGGG	LTBP1	ENSG00000049323	-0.7008385215102662	[31,39]	[9,2]	-6	dCas9-VP64	positive selection	2558372
32996429	32996452	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAACATATGAATTTTGGGAGAG	LTBP1	ENSG00000049323	-0.3596175999355018	[86,172]	[39,25]	-4	dCas9-VP64	positive selection	2558549
33368100	33368123	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGGCTGAGGCAGGAGAATAG	LTBP1	ENSG00000049323	-0.1093774260535414	[64,117]	[17,35]	-1	dCas9-VP64	positive selection	2563779
33356572	33356595	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	AGGAGGCTGAGGCAGGAGAATGG	LTBP1	ENSG00000049323	-0.1093774260535414	[64,117]	[17,35]	-1	dCas9-VP64	positive selection	2563877
33204670	33204693	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGAGGATCACTTGAGCCCGAG	LTBP1	ENSG00000049323	0.9689409693551694	[107,845]	[92,495]	6	dCas9-VP64	positive selection	2565022
32950322	32950345	2	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGGTGGGTGGATCACTTGAGG	LTBP1	ENSG00000049323	0.9990680086899741	[19,33]	[6,26]	6	dCas9-VP64	positive selection	2567082
32947207	32947230	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	AGCTGCCGAGAGCCCGGGAAAGG	LTBP1	ENSG00000049323	1.8680584736474355	[232,172]	[356,136]	8	dCas9-VP64	positive selection	2572986
32947185	32947208	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GCGGGAGGAGACCAAGTCGGTGG	LTBP1	ENSG00000049323	2.570739628279159	[11,43]	[11,93]	9	dCas9-VP64	positive selection	2572987
32947119	32947142	2	-	25494202	A375	resistance to PLX-4720 (zeocin)	GGCCGATTGTGGCTGGGAGCAGG	LTBP1	ENSG00000049323	0.45039716174663225	[6,9]	[4,1]	3	dCas9-VP64	positive selection	2572988
33188780	33188803	2	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.2682705498761727	[4,3]	[2,2]	-4	hSpCas9	positive selection	3000455
33217566	33217589	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTCTTGCTTTGAAAGGCCAGGG	LTBP1	ENSG00000049323	0.3998464790142811	[3,2]	[5,2]	8	hSpCas9	positive selection	3000456
33188794	33188817	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGTGTCTTAGCAGCCACGGGG	LTBP1	ENSG00000049323	0.5352735438011664	[3,3]	[3,6]	9	hSpCas9	positive selection	3000457
33188631	33188654	2	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TGAAACCTGATGTATCTGGACGG	LTBP1	ENSG00000049323	-0.0641742299933204	[2,3]	[2,2]	-1	hSpCas9	positive selection	3000458
33188780	33188803	2	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.281393568846361	[4,4]	[4,2]	5	hSpCas9	positive selection	3068313
33217566	33217589	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTCTTGCTTTGAAAGGCCAGGG	LTBP1	ENSG00000049323	-0.593402207011591	[3,3]	[1,0]	-7	hSpCas9	positive selection	3068314
33188794	33188817	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGTGTCTTAGCAGCCACGGGG	LTBP1	ENSG00000049323	0.29322960604655735	[3,3]	[3,2]	5	hSpCas9	positive selection	3068315
33188631	33188654	2	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TGAAACCTGATGTATCTGGACGG	LTBP1	ENSG00000049323	0.9245179077837042	[2,2]	[4,3]	9	hSpCas9	positive selection	3068316
33188626	33188649		+	24336571	A375	resistance to PLX after 7 days	AGCTTCCGTCCAGATACATCAGG	LTBP1	ENSG00000049323	-0.1316419733367482	[37,28]	[26,33]	-4	hSpCas9	positive selection	3125645
33188702	33188725		+	24336571	A375	resistance to PLX after 7 days	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.04792764704994701	[60,60]	[59,55]	-1	hSpCas9	positive selection	3125646
33188779	33188802		+	24336571	A375	resistance to PLX after 7 days	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.2662219371031034	[57,47]	[62,63]	7	hSpCas9	positive selection	3125648
33021159	33021182		+	24336571	A375	resistance to PLX after 7 days	CCTCAAGCCGAAGCCTTCAGTGG	LTBP1	ENSG00000049323	-0.20531193139849802	[7,5]	[5,5]	-6	hSpCas9	positive selection	3125649
33243737	33243760		-	24336571	A375	resistance to PLX after 7 days	CGGCCCAAATCCTATTTTGCAGG	LTBP1	ENSG00000049323	-0.14769453684915623	[27,35]	[25,30]	-5	hSpCas9	positive selection	3125650
33110612	33110635		+	24336571	A375	resistance to PLX after 7 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.013694918238061765	[10,11]	[10,10]	0	hSpCas9	positive selection	3125651
33021076	33021099		-	24336571	A375	resistance to PLX after 7 days	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.026873044259242224	[16,13]	[15,13]	0	hSpCas9	positive selection	3125652
33243727	33243750		+	24336571	A375	resistance to PLX after 7 days	TATCGATGTACCTGCAAAATAGG	LTBP1	ENSG00000049323	0.10724890713563973	[55,63]	[67,60]	3	hSpCas9	positive selection	3125653
33110630	33110653		-	24336571	A375	resistance to PLX after 7 days	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.0918371829777842	[30,29]	[29,34]	3	hSpCas9	positive selection	3125654
33020914	33020937		+	24336571	A375	resistance to PLX after 7 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	-0.15294441346515436	[14,13]	[11,13]	-5	hSpCas9	positive selection	3125655
33188626	33188649		+	24336571	A375	resistance to PLX after 14 days	AGCTTCCGTCCAGATACATCAGG	LTBP1	ENSG00000049323	-0.28946095877663913	[33,22]	[8,11]	-3	hSpCas9	positive selection	3183438
33188702	33188725		+	24336571	A375	resistance to PLX after 14 days	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.029072269651049254	[80,48]	[29,28]	0	hSpCas9	positive selection	3183439
33188779	33188802		+	24336571	A375	resistance to PLX after 14 days	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.20345067576113518	[66,44]	[21,22]	-2	hSpCas9	positive selection	3183441
33021159	33021182		+	24336571	A375	resistance to PLX after 14 days	CCTCAAGCCGAAGCCTTCAGTGG	LTBP1	ENSG00000049323	-0.6890386625791498	[5,9]	[1,1]	-7	hSpCas9	positive selection	3183442
33243737	33243760		-	24336571	A375	resistance to PLX after 14 days	CGGCCCAAATCCTATTTTGCAGG	LTBP1	ENSG00000049323	0.397873686949497	[33,32]	[19,19]	4	hSpCas9	positive selection	3183443
33110612	33110635		+	24336571	A375	resistance to PLX after 14 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.43150946245835253	[13,15]	[4,4]	-5	hSpCas9	positive selection	3183444
33021076	33021099		-	24336571	A375	resistance to PLX after 14 days	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.6511779843036136	[16,16]	[3,4]	-7	hSpCas9	positive selection	3183445
33243727	33243750		+	24336571	A375	resistance to PLX after 14 days	TATCGATGTACCTGCAAAATAGG	LTBP1	ENSG00000049323	-0.3722503511068309	[60,74]	[25,21]	-4	hSpCas9	positive selection	3183446
33110630	33110653		-	24336571	A375	resistance to PLX after 14 days	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.08794401685784203	[37,36]	[19,16]	1	hSpCas9	positive selection	3183447
33020914	33020937		+	24336571	A375	resistance to PLX after 14 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	-0.9212790155013986	[17,19]	[3,3]	-9	hSpCas9	positive selection	3183448
33188626	33188649		+	24336571	A375	viability after 7 days	AGCTTCCGTCCAGATACATCAGG	LTBP1	ENSG00000049323	-0.025793467980423923	[35]	[37,28]	0	hSpCas9	negative selection	3241231
33188702	33188725		+	24336571	A375	viability after 7 days	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.021711292814226457	[64]	[60,60]	0	hSpCas9	negative selection	3241232
33188779	33188802		+	24336571	A375	viability after 7 days	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.18095003015598898	[62]	[57,47]	-3	hSpCas9	negative selection	3241234
33021159	33021182		+	24336571	A375	viability after 7 days	CCTCAAGCCGAAGCCTTCAGTGG	LTBP1	ENSG00000049323	-0.06991890289997571	[7]	[7,5]	-1	hSpCas9	negative selection	3241235
33243737	33243760		-	24336571	A375	viability after 7 days	CGGCCCAAATCCTATTTTGCAGG	LTBP1	ENSG00000049323	0.028205628093165735	[32]	[27,35]	0	hSpCas9	negative selection	3241236
33110612	33110635		+	24336571	A375	viability after 7 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.19876372409545828	[10]	[10,11]	3	hSpCas9	negative selection	3241237
33021076	33021099		-	24336571	A375	viability after 7 days	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.018285797949163463	[15]	[16,13]	0	hSpCas9	negative selection	3241238
33243727	33243750		+	24336571	A375	viability after 7 days	TATCGATGTACCTGCAAAATAGG	LTBP1	ENSG00000049323	0.021336844862042792	[61]	[55,63]	0	hSpCas9	negative selection	3241239
33110630	33110653		-	24336571	A375	viability after 7 days	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.6798180283547022	[19]	[30,29]	8	hSpCas9	negative selection	3241240
33020914	33020937		+	24336571	A375	viability after 7 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.4504068184398924	[10]	[14,13]	6	hSpCas9	negative selection	3241241
33188626	33188649		+	24336571	A375	viability after 14 days	AGCTTCCGTCCAGATACATCAGG	LTBP1	ENSG00000049323	-0.24029764653317054	[35]	[33,22]	-3	hSpCas9	negative selection	3299024
33188702	33188725		+	24336571	A375	viability after 14 days	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.09572543498390651	[64]	[80,48]	1	hSpCas9	negative selection	3299025
33188779	33188802		+	24336571	A375	viability after 14 days	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.08773045606662855	[62]	[66,44]	-1	hSpCas9	negative selection	3299027
33021159	33021182		+	24336571	A375	viability after 14 days	CCTCAAGCCGAAGCCTTCAGTGG	LTBP1	ENSG00000049323	0.10375700641773733	[7]	[5,9]	1	hSpCas9	negative selection	3299028
33243737	33243760		-	24336571	A375	viability after 14 days	CGGCCCAAATCCTATTTTGCAGG	LTBP1	ENSG00000049323	0.09466895139703557	[32]	[33,32]	1	hSpCas9	negative selection	3299029
33110612	33110635		+	24336571	A375	viability after 14 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.5732387476700675	[10]	[13,15]	7	hSpCas9	negative selection	3299030
33021076	33021099		-	24336571	A375	viability after 14 days	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.1458772069711765	[15]	[16,16]	2	hSpCas9	negative selection	3299031
33243727	33243750		+	24336571	A375	viability after 14 days	TATCGATGTACCTGCAAAATAGG	LTBP1	ENSG00000049323	0.20935503188913573	[61]	[60,74]	2	hSpCas9	negative selection	3299032
33110630	33110653		-	24336571	A375	viability after 14 days	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.9762047228070256	[19]	[37,36]	9	hSpCas9	negative selection	3299033
33020914	33020937		+	24336571	A375	viability after 14 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.8366985779109009	[10]	[17,19]	9	hSpCas9	negative selection	3299034
33021076	33021099	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.09140194278524241	[162,162]	[0,0]	0	hSpCas9	positive selection	3377900
33021189	33021212	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	2.7978945928085377	[21,21]	[0,0]	8	hSpCas9	positive selection	3377901
33110709	33110732	2	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-1.1980010088587256	[350,350]	[0,0]	-7	hSpCas9	positive selection	3377902
33188779	33188802	2	+	26780180	HT29	viability (Avana library 4 designs)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.0194011529203906	[]	[]	0	hSpCas9	negative selection	3438039
33217566	33217589	2	-	26780180	HT29	viability (Avana library 4 designs)	CCTCTTGCTTTGAAAGGCCAGGG	LTBP1	ENSG00000049323	0.910825460408061	[]	[]	3	hSpCas9	negative selection	3438040
33188794	33188817	2	-	26780180	HT29	viability (Avana library 4 designs)	GCTGTGTCTTAGCAGCCACGGGG	LTBP1	ENSG00000049323	0.496468430978463	[]	[]	1	hSpCas9	negative selection	3438041
33188631	33188654	2	-	26780180	HT29	viability (Avana library 4 designs)	TGAAACCTGATGTATCTGGACGG	LTBP1	ENSG00000049323	0.973080060074252	[]	[]	4	hSpCas9	negative selection	3438042
33188794	33188817	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGTGTCTTAGCAGCCACGGGG	LTBP1	ENSG00000049323	4.64664428614686	[]	[]	7	hSpCas9	negative selection	3527047
33188779	33188802	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.1163546604266	[]	[]	0	hSpCas9	negative selection	3527048
33188631	33188654	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGAAACCTGATGTATCTGGACGG	LTBP1	ENSG00000049323	2.2025843742876	[]	[]	3	hSpCas9	negative selection	3527049
33217566	33217589	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTCTTGCTTTGAAAGGCCAGGG	LTBP1	ENSG00000049323	3.39131998492979	[]	[]	5	hSpCas9	negative selection	3527050
33134938	33134961	2	+	26780180	A375	viability (Avana lentiCRISPRv2)	GACGGCCACGAACTTCCGAGTGG	LTBP1	ENSG00000049323	1.59429985476845	[]	[]	2	hSpCas9	negative selection	3527051
33252750	33252773	2	-	26780180	A375	viability (Avana lentiCRISPRv2)	TGGTGAGGTGAACAGACAGAGGG	LTBP1	ENSG00000049323	4.53323142361916	[]	[]	7	hSpCas9	negative selection	3527052
33188794	33188817	2	-	26780180	A375	viability (Avana lentiGuide)	GCTGTGTCTTAGCAGCCACGGGG	LTBP1	ENSG00000049323	-2.31354693613922	[]	[]	-4	hSpCas9	negative selection	3635706
33188779	33188802	2	+	26780180	A375	viability (Avana lentiGuide)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	3.05557203944638	[]	[]	3	hSpCas9	negative selection	3635707
33188631	33188654	2	-	26780180	A375	viability (Avana lentiGuide)	TGAAACCTGATGTATCTGGACGG	LTBP1	ENSG00000049323	1.73129726878071	[]	[]	2	hSpCas9	negative selection	3635708
33217566	33217589	2	-	26780180	A375	viability (Avana lentiGuide)	CCTCTTGCTTTGAAAGGCCAGGG	LTBP1	ENSG00000049323	0.216657774521538	[]	[]	0	hSpCas9	negative selection	3635709
33134938	33134961	2	+	26780180	A375	viability (Avana lentiGuide)	GACGGCCACGAACTTCCGAGTGG	LTBP1	ENSG00000049323	3.74849400137661	[]	[]	3	hSpCas9	negative selection	3635710
33252750	33252773	2	-	26780180	A375	viability (Avana lentiGuide)	TGGTGAGGTGAACAGACAGAGGG	LTBP1	ENSG00000049323	-0.732613804551063	[]	[]	-1	hSpCas9	negative selection	3635711
33188794	33188817	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGTGTCTTAGCAGCCACGGGG	LTBP1	ENSG00000049323	0.18098827067755907	[4]	[5,4]	5	hSpCas9	positive selection	3744365
33188779	33188802	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.05228815371889875	[4]	[4,4]	-1	hSpCas9	positive selection	3744366
33188631	33188654	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGAAACCTGATGTATCTGGACGG	LTBP1	ENSG00000049323	-0.16948639142194338	[5]	[4,4]	-3	hSpCas9	positive selection	3744367
33217566	33217589	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTCTTGCTTTGAAAGGCCAGGG	LTBP1	ENSG00000049323	0.2631484847187144	[5]	[6,6]	7	hSpCas9	positive selection	3744368
33134938	33134961	2	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GACGGCCACGAACTTCCGAGTGG	LTBP1	ENSG00000049323	0.2401534684603259	[4]	[5,4]	6	hSpCas9	positive selection	3744369
33252750	33252773	2	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TGGTGAGGTGAACAGACAGAGGG	LTBP1	ENSG00000049323	0.2239926593188868	[4]	[5,4]	6	hSpCas9	positive selection	3744370
33188794	33188817	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGTGTCTTAGCAGCCACGGGG	LTBP1	ENSG00000049323	0.160934569159873	[5]	[5,5]	4	hSpCas9	positive selection	3852972
33188779	33188802	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.07444482821902519	[6]	[5,4]	-1	hSpCas9	positive selection	3852973
33188631	33188654	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGAAACCTGATGTATCTGGACGG	LTBP1	ENSG00000049323	-0.23785017382081675	[5]	[2,4]	-3	hSpCas9	positive selection	3852974
33217566	33217589	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTCTTGCTTTGAAAGGCCAGGG	LTBP1	ENSG00000049323	0.021510251906337315	[5]	[3,5]	0	hSpCas9	positive selection	3852975
33134938	33134961	2	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GACGGCCACGAACTTCCGAGTGG	LTBP1	ENSG00000049323	-0.06799397738069284	[5]	[4,4]	-1	hSpCas9	positive selection	3852976
33252750	33252773	2	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TGGTGAGGTGAACAGACAGAGGG	LTBP1	ENSG00000049323	0.08933702269846719	[4]	[4,3]	2	hSpCas9	positive selection	3852977
33188702	33188725	2	+	26780180	A375	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.335379789945294	[]	[]	0	hSpCas9	negative selection	3958613
33188779	33188802	2	+	26780180	A375	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.767936368756229	[]	[]	3	hSpCas9	negative selection	3958614
33021189	33021212	2	-	26780180	A375	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.998203165187079	[]	[]	4	hSpCas9	negative selection	3958615
33021076	33021099	2	-	26780180	A375	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.77213933993311	[]	[]	3	hSpCas9	negative selection	3958616
33110709	33110732	2	-	26780180	A375	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.751875721395365	[]	[]	2	hSpCas9	negative selection	3958617
33110630	33110653	2	-	26780180	A375	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	1.43568296717936	[]	[]	8	hSpCas9	negative selection	3958618
33188702	33188725	2	+	26780180	HT29	viability (GeCKOv2 library)	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.515423831933313	[]	[]	1	hSpCas9	negative selection	4066579
33188779	33188802	2	+	26780180	HT29	viability (GeCKOv2 library)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.281078142567939	[]	[]	0	hSpCas9	negative selection	4066580
33021189	33021212	2	-	26780180	HT29	viability (GeCKOv2 library)	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.932643352349768	[]	[]	4	hSpCas9	negative selection	4066581
33021076	33021099	2	-	26780180	HT29	viability (GeCKOv2 library)	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	1.79914084125965	[]	[]	8	hSpCas9	negative selection	4066582
33110709	33110732	2	-	26780180	HT29	viability (GeCKOv2 library)	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	1.18466614171211	[]	[]	6	hSpCas9	negative selection	4066583
33110630	33110653	2	-	26780180	HT29	viability (GeCKOv2 library)	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	1.08518447834517	[]	[]	5	hSpCas9	negative selection	4066584
33188626	33188649	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCTTCCGTCCAGATACATCAGG	LTBP1	ENSG00000049323	0.1375152428526828	[5]	[4,3]	3	hSpCas9	positive selection	4149808
33188702	33188725	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.1897747639847851	[6]	[4,4]	5	hSpCas9	positive selection	4149809
33188779	33188802	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.09719077015432642	[5]	[3,4]	2	hSpCas9	positive selection	4149811
33021159	33021182	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCTCAAGCCGAAGCCTTCAGTGG	LTBP1	ENSG00000049323	-0.1746165627325359	[2]	[1,0]	-4	hSpCas9	positive selection	4149812
33243737	33243760	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CGGCCCAAATCCTATTTTGCAGG	LTBP1	ENSG00000049323	0.1676390865253936	[4]	[2,4]	4	hSpCas9	positive selection	4149813
33110612	33110635	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.19124736255152228	[3]	[2,2]	5	hSpCas9	positive selection	4149814
33021076	33021099	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.15925819190501955	[3]	[1,2]	-4	hSpCas9	positive selection	4149815
33243727	33243750	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TATCGATGTACCTGCAAAATAGG	LTBP1	ENSG00000049323	0.25067679239990126	[5]	[4,4]	6	hSpCas9	positive selection	4149816
33110630	33110653	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.11285775379981472	[4]	[2,4]	3	hSpCas9	positive selection	4149817
33020914	33020937	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	-0.007967895500335553	[3]	[1,1]	0	hSpCas9	positive selection	4149818
33188626	33188649	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCTTCCGTCCAGATACATCAGG	LTBP1	ENSG00000049323	0.5723602918115451	[5]	[1,2,4,3]	4	hSpCas9	positive selection	4213830
33188702	33188725	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	1.0891297952919567	[5]	[4,4,4,5]	7	hSpCas9	positive selection	4213831
33188779	33188802	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.9487017045931182	[5]	[4,4,4,4]	6	hSpCas9	positive selection	4213833
33021159	33021182	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCTCAAGCCGAAGCCTTCAGTGG	LTBP1	ENSG00000049323	-0.24930077618362156	[3]	[3,0,0,0]	-4	hSpCas9	positive selection	4213834
33243737	33243760	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CGGCCCAAATCCTATTTTGCAGG	LTBP1	ENSG00000049323	0.025728434707978476	[4]	[3,0,4,0]	0	hSpCas9	positive selection	4213835
33110612	33110635	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.6389543535563469	[3]	[5,3,1,0]	4	hSpCas9	positive selection	4213836
33021076	33021099	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.2543783863858907	[2]	[4,0,0,0]	2	hSpCas9	positive selection	4213837
33243727	33243750	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TATCGATGTACCTGCAAAATAGG	LTBP1	ENSG00000049323	1.0602580232269765	[6]	[5,5,5,5]	7	hSpCas9	positive selection	4213838
33110630	33110653	2	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.9068286491211277	[4]	[1,3,1,4]	6	hSpCas9	positive selection	4213839
33020914	33020937	2	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.44453144956305574	[1]	[0,1,2,0]	3	hSpCas9	positive selection	4213840
33188702	33188725	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.45082585380859175	[3]	[4,3]	8	hSpCas9	positive selection	4281249
33110630	33110653	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	-0.4219094066343344	[3]	[3,0]	-7	hSpCas9	positive selection	4281250
33188779	33188802	2	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.29645543484049997	[3]	[3,4]	6	hSpCas9	positive selection	4281251
33021076	33021099	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.2296267868554479	[2]	[3,1]	4	hSpCas9	positive selection	4345508
33021189	33021212	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.019522028103488243	[1]	[1,0]	0	hSpCas9	positive selection	4345509
33110709	33110732	2	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.35148097763049235	[3]	[3,3]	7	hSpCas9	positive selection	4345510
33134940	33134962	2	+	27760321	OCIAML3	viability	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	-0.0904657852090911	[658,499]	[321,552]	-1	hSpCas9	negative selection	4415720
33188703	33188725	2	+	27760321	OCIAML3	viability	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.1449503863925406	[595,511]	[290,720]	1	hSpCas9	negative selection	4415721
33188780	33188802	2	+	27760321	OCIAML3	viability	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.5687845408800634	[767,707]	[872,833]	6	hSpCas9	negative selection	4415722
33222111	33222133	2	-	27760321	OCIAML3	viability	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	-0.0964410368528687	[641,481]	[355,474]	-1	hSpCas9	negative selection	4415723
33243716	33243738	2	-	27760321	OCIAML3	viability	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.17374844663500416	[640,517]	[517,495]	2	hSpCas9	negative selection	4415724
33134940	33134962	2	+	27760321	OCIAML2	viability	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.5227267551795063	[658,499]	[586,774]	7	hSpCas9	negative selection	4499183
33188703	33188725	2	+	27760321	OCIAML2	viability	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.17393588299301854	[595,511]	[488,523]	2	hSpCas9	negative selection	4499184
33188780	33188802	2	+	27760321	OCIAML2	viability	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.39793568847243943	[767,707]	[761,818]	5	hSpCas9	negative selection	4499185
33222111	33222133	2	-	27760321	OCIAML2	viability	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.5833184261130866	[641,481]	[608,762]	7	hSpCas9	negative selection	4499186
33243716	33243738	2	-	27760321	OCIAML2	viability	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	-0.004348111910341346	[640,517]	[403,544]	0	hSpCas9	negative selection	4499187
33134940	33134962	2	+	27760321	MV411	viability	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	-0.03223984414488135	[658,499]	[344,409]	0	hSpCas9	negative selection	4582646
33188703	33188725	2	+	27760321	MV411	viability	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	1.8634719985646508	[595,511]	[1554,982]	9	hSpCas9	negative selection	4582647
33188780	33188802	2	+	27760321	MV411	viability	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.8973262374111641	[767,707]	[974,804]	6	hSpCas9	negative selection	4582648
33222111	33222133	2	-	27760321	MV411	viability	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	1.518673957514534	[641,481]	[1175,869]	9	hSpCas9	negative selection	4582649
33243716	33243738	2	-	27760321	MV411	viability	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.2061356341189549	[640,517]	[624,158]	1	hSpCas9	negative selection	4582650
33134940	33134962	2	+	27760321	HL60	viability	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	-0.18802470186469464	[658,499]	[402,421]	-2	hSpCas9	negative selection	4666109
33188703	33188725	2	+	27760321	HL60	viability	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.29410328710925726	[595,511]	[544,561]	3	hSpCas9	negative selection	4666110
33188780	33188802	2	+	27760321	HL60	viability	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	1.4775460741662665	[767,707]	[1519,1846]	9	hSpCas9	negative selection	4666111
33222111	33222133	2	-	27760321	HL60	viability	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.2544061472726278	[641,481]	[410,682]	3	hSpCas9	negative selection	4666112
33243716	33243738	2	-	27760321	HL60	viability	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	-0.4022713429848635	[640,517]	[380,329]	-4	hSpCas9	negative selection	4666113
33134940	33134962	2	+	27760321	HT1080	viability	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.5957161920772254	[499,389]	[233,304]	3	hSpCas9	negative selection	4749572
33188703	33188725	2	+	27760321	HT1080	viability	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.06789293092222742	[511,399]	[179,165]	0	hSpCas9	negative selection	4749573
33188780	33188802	2	+	27760321	HT1080	viability	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	2.678840266863428	[707,552]	[1427,1805]	9	hSpCas9	negative selection	4749574
33222111	33222133	2	-	27760321	HT1080	viability	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.4047840854267064	[481,375]	[104,358]	2	hSpCas9	negative selection	4749575
33243716	33243738	2	-	27760321	HT1080	viability	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	-0.8501432585155189	[517,403]	[56,150]	-4	hSpCas9	negative selection	4749576
33134940	33134962	2	+	27760321	HT29	viability after 7 days	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.5660300481956893	[499,389]	[1145,608,827]	8	hSpCas9	negative selection	4833035
33188703	33188725	2	+	27760321	HT29	viability after 7 days	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.15055012865597234	[511,399]	[777,455,389]	-2	hSpCas9	negative selection	4833036
33188780	33188802	2	+	27760321	HT29	viability after 7 days	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.060812338774950736	[707,552]	[870,1103,572]	0	hSpCas9	negative selection	4833037
33222111	33222133	2	-	27760321	HT29	viability after 7 days	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.6343466886579822	[481,375]	[660,692,1174]	8	hSpCas9	negative selection	4833038
33243716	33243738	2	-	27760321	HT29	viability after 7 days	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.2725505265048085	[517,403]	[724,927,501]	4	hSpCas9	negative selection	4833039
33134940	33134962	2	+	27760321	HT29	viability after 25 days	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.3229098562626827	[499,389]	[541,435,969]	3	hSpCas9	negative selection	4916498
33188703	33188725	2	+	27760321	HT29	viability after 25 days	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.32563324015927403	[511,399]	[739,627,576]	3	hSpCas9	negative selection	4916499
33188780	33188802	2	+	27760321	HT29	viability after 25 days	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.5551758032642051	[707,552]	[968,1207,996]	6	hSpCas9	negative selection	4916500
33222111	33222133	2	-	27760321	HT29	viability after 25 days	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	1.0123903910466845	[481,375]	[887,954,1144]	9	hSpCas9	negative selection	4916501
33243716	33243738	2	-	27760321	HT29	viability after 25 days	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.3184716572235271	[517,403]	[604,694,674]	3	hSpCas9	negative selection	4916502
33134940	33134962	2	+	27760321	HT29	viability after 22 days	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.7675075343531215	[499,389]	[1014,768,838]	8	hSpCas9	negative selection	4999961
33188703	33188725	2	+	27760321	HT29	viability after 22 days	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.11356779069418954	[511,399]	[519,563,628]	1	hSpCas9	negative selection	4999962
33188780	33188802	2	+	27760321	HT29	viability after 22 days	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.16363271159171477	[707,552]	[687,932,831]	1	hSpCas9	negative selection	4999963
33222111	33222133	2	-	27760321	HT29	viability after 22 days	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.6910729951740543	[481,375]	[780,769,851]	7	hSpCas9	negative selection	4999964
33243716	33243738	2	-	27760321	HT29	viability after 22 days	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.20122731878640132	[517,403]	[560,708,568]	2	hSpCas9	negative selection	4999965
33134940	33134962	2	+	27760321	HT29	viability after 19 days	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.7232813668931088	[499,389]	[1174,511,866]	7	hSpCas9	negative selection	5083424
33188703	33188725	2	+	27760321	HT29	viability after 19 days	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.1652256179739467	[511,399]	[1055,445,311]	1	hSpCas9	negative selection	5083425
33188780	33188802	2	+	27760321	HT29	viability after 19 days	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.11835631997881446	[707,552]	[848,622,878]	1	hSpCas9	negative selection	5083426
33222111	33222133	2	-	27760321	HT29	viability after 19 days	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	1.355344890519732	[481,375]	[832,1770,1121]	9	hSpCas9	negative selection	5083427
33243716	33243738	2	-	27760321	HT29	viability after 19 days	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.5932195499344978	[517,403]	[686,993,696]	6	hSpCas9	negative selection	5083428
33134940	33134962	2	+	27760321	HT29	viability after 16 days	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.8935899858693663	[499,389]	[978,1141,652]	9	hSpCas9	negative selection	5166887
33188703	33188725	2	+	27760321	HT29	viability after 16 days	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.05802836035413689	[511,399]	[645,448,390]	0	hSpCas9	negative selection	5166888
33188780	33188802	2	+	27760321	HT29	viability after 16 days	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.2497523040754006	[707,552]	[914,814,793]	2	hSpCas9	negative selection	5166889
33222111	33222133	2	-	27760321	HT29	viability after 16 days	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.6322602849434634	[481,375]	[680,1038,497]	7	hSpCas9	negative selection	5166890
33243716	33243738	2	-	27760321	HT29	viability after 16 days	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	-0.2771750811301679	[517,403]	[335,626,299]	-3	hSpCas9	negative selection	5166891
33134940	33134962	2	+	27760321	HT29	viability after 13 days	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.6452973876068371	[499,389]	[941,539,931]	8	hSpCas9	negative selection	5250350
33188703	33188725	2	+	27760321	HT29	viability after 13 days	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.3013443698829949	[511,399]	[716,713,531]	4	hSpCas9	negative selection	5250351
33188780	33188802	2	+	27760321	HT29	viability after 13 days	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.22448988576860596	[707,552]	[764,944,853]	2	hSpCas9	negative selection	5250352
33222111	33222133	2	-	27760321	HT29	viability after 13 days	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.7692993914752833	[481,375]	[1100,662,783]	8	hSpCas9	negative selection	5250353
33243716	33243738	2	-	27760321	HT29	viability after 13 days	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.11135945117513346	[517,403]	[430,752,550]	1	hSpCas9	negative selection	5250354
33134940	33134962	2	+	27760321	HT29	viability after 10 days	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.5118802485159688	[499,389]	[733,827,814]	7	hSpCas9	negative selection	5333813
33188703	33188725	2	+	27760321	HT29	viability after 10 days	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.300152763756604	[511,399]	[1109,576,418]	4	hSpCas9	negative selection	5333814
33188780	33188802	2	+	27760321	HT29	viability after 10 days	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.2718820419980754	[707,552]	[983,1007,862]	3	hSpCas9	negative selection	5333815
33222111	33222133	2	-	27760321	HT29	viability after 10 days	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	0.7878960790768714	[481,375]	[928,959,886]	9	hSpCas9	negative selection	5333816
33243716	33243738	2	-	27760321	HT29	viability after 10 days	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.02316747557392973	[517,403]	[761,514,477]	0	hSpCas9	negative selection	5333817
33134940	33134962	2	+	27760321	MOLM13	viability	CGGCCACGAACTTCCGAGTGGG	LTBP1	ENSG00000049323	0.6135808289866653	[658,499]	[290,670]	4	hSpCas9	negative selection	5417276
33188703	33188725	2	+	27760321	MOLM13	viability	AATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.06548632767911844	[595,511]	[380,226]	0	hSpCas9	negative selection	5417277
33188780	33188802	2	+	27760321	MOLM13	viability	ATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.6472582681984598	[767,707]	[623,675]	4	hSpCas9	negative selection	5417278
33222111	33222133	2	-	27760321	MOLM13	viability	AACCCGCTTATAACCCGGTAGG	LTBP1	ENSG00000049323	1.4655453887574303	[641,481]	[1576,264]	8	hSpCas9	negative selection	5417279
33243716	33243738	2	-	27760321	MOLM13	viability	GTACATCGATAGCTGCCCATGG	LTBP1	ENSG00000049323	0.4573281975542401	[640,517]	[493,405]	3	hSpCas9	negative selection	5417280
33134582	33134605	2	-	27661255	K562	viability	GGTGTCTCTGAAACAGGAGTAGG	LTBP1	ENSG00000049323	-0.06492600361779313	[757,775]	[612,561]	-2	dCas9-KRAB	negative selection	5491318
33134603	33134626	2	-	27661255	K562	viability	GCTCGCTGCTCTGTATTCAGTGG	LTBP1	ENSG00000049323	0.008205053387460026	[162,164]	[121,139]	0	dCas9-KRAB	negative selection	5491319
33134652	33134675	2	-	27661255	K562	viability	GAGAGAGCCCACAACCCGACAGG	LTBP1	ENSG00000049323	0.07712777141639737	[994,754]	[808,682]	2	dCas9-KRAB	negative selection	5491320
33135029	33135052	2	-	27661255	K562	viability	GACAGCAGTGTGAATGGAGGGGG	LTBP1	ENSG00000049323	-0.03116370198696472	[1001,1018]	[901,693]	-1	dCas9-KRAB	negative selection	5491321
33135032	33135055	2	-	27661255	K562	viability	GCAGACAGCAGTGTGAATGGAGG	LTBP1	ENSG00000049323	0.004522143085485153	[1655,1729]	[1442,1280]	0	dCas9-KRAB	negative selection	5491322
33135035	33135058	2	-	27661255	K562	viability	GAAGCAGACAGCAGTGTGAATGG	LTBP1	ENSG00000049323	0.15677860200547888	[921,975]	[908,788]	5	dCas9-KRAB	negative selection	5491323
33188702	33188725	2	+	27260156	BXPC3	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.037355780783751236	[731]	[650,816,740,960]	0	hSpCas9	negative selection	5553709
33110630	33110653	2	-	27260156	BXPC3	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.017918086469013828	[878]	[744,926,970,1116]	0	hSpCas9	negative selection	5553710
33188779	33188802	2	+	27260156	BXPC3	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.16530804024176482	[955]	[1020,960,1300,1229]	3	hSpCas9	negative selection	5553711
33021076	33021099	2	-	27260156	BXPC3	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.05207831593992773	[386]	[375,339,384,471]	-1	hSpCas9	negative selection	5617968
33021189	33021212	2	-	27260156	BXPC3	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.08923915280352057	[104]	[145,70,121,65]	-2	hSpCas9	negative selection	5617969
33110709	33110732	2	-	27260156	BXPC3	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.1426313524892175	[621]	[580,789,744,767]	3	hSpCas9	negative selection	5617970
33188702	33188725	2	+	27260156	A673	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.00981616892832371	[731]	[848,804,878,960]	0	hSpCas9	negative selection	5674960
33110630	33110653	2	-	27260156	A673	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.08558361609675547	[878]	[1153,1037,1187,1101]	2	hSpCas9	negative selection	5674961
33188779	33188802	2	+	27260156	A673	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.13366645328788418	[955]	[1367,1104,1257,1323]	3	hSpCas9	negative selection	5674962
33021076	33021099	2	-	27260156	A673	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.04696391854316323	[386]	[556,424,393,434]	-1	hSpCas9	negative selection	5739219
33021189	33021212	2	-	27260156	A673	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.8759303199637176	[104]	[85,53,68,67]	-9	hSpCas9	negative selection	5739220
33110709	33110732	2	-	27260156	A673	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.09920140303679847	[621]	[694,708,700,680]	-2	hSpCas9	negative selection	5739221
33188702	33188725	2	+	27260156	A375	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.20791087388605745	[731]	[693,569,975,698]	-3	hSpCas9	negative selection	5796211
33110630	33110653	2	-	27260156	A375	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.22681792269807044	[878]	[1181,1551,1267,885]	3	hSpCas9	negative selection	5796212
33188779	33188802	2	+	27260156	A375	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.04423090240662764	[955]	[910,1604,1264,667]	0	hSpCas9	negative selection	5796213
33021076	33021099	2	-	27260156	A375	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.24589903042984548	[386]	[438,576,613,518]	3	hSpCas9	negative selection	5860470
33021189	33021212	2	-	27260156	A375	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.19745036001887817	[104]	[207,92,161,97]	3	hSpCas9	negative selection	5860471
33110709	33110732	2	-	27260156	A375	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.34348909453472826	[621]	[1245,867,998,603]	5	hSpCas9	negative selection	5860472
33188702	33188725	2	+	27260156	COLO741	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.1735169790274138	[731]	[883,908,706]	-4	hSpCas9	negative selection	5917462
33110630	33110653	2	-	27260156	COLO741	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.2182578083395197	[878]	[1502,1207,1227]	4	hSpCas9	negative selection	5917463
33188779	33188802	2	+	27260156	COLO741	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.16238829788446174	[955]	[1304,1631,1170]	3	hSpCas9	negative selection	5917464
33021076	33021099	2	-	27260156	COLO741	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.0927504026229381	[386]	[577,420,404]	-2	hSpCas9	negative selection	5981721
33021189	33021212	2	-	27260156	COLO741	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.2896412973932234	[104]	[120,71,134]	-6	hSpCas9	negative selection	5981722
33110709	33110732	2	-	27260156	COLO741	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.006052530370459386	[621]	[766,770,847]	0	hSpCas9	negative selection	5981723
33188702	33188725	2	+	27260156	CAL120	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.14230349638386214	[731]	[822,809,841]	-2	hSpCas9	negative selection	6038713
33110630	33110653	2	-	27260156	CAL120	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.06088946285688268	[878]	[1153,1330,942]	0	hSpCas9	negative selection	6038714
33188779	33188802	2	+	27260156	CAL120	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.29762822706535874	[955]	[1771,1610,1056]	4	hSpCas9	negative selection	6038715
33021076	33021099	2	-	27260156	CAL120	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.21832049057341024	[386]	[672,547,477]	3	hSpCas9	negative selection	6102972
33021189	33021212	2	-	27260156	CAL120	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-1.8573950119941114	[104]	[44,55,8]	-9	hSpCas9	negative selection	6102973
33110709	33110732	2	-	27260156	CAL120	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.07972065473090822	[621]	[1033,627,823]	1	hSpCas9	negative selection	6102974
33188702	33188725	2	+	27260156	CADOES1	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.15956578866810878	[731]	[546,570,662,658]	-3	hSpCas9	negative selection	6159964
33110630	33110653	2	-	27260156	CADOES1	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.47164992247012205	[878]	[907,1416,1147,1059]	7	hSpCas9	negative selection	6159965
33188779	33188802	2	+	27260156	CADOES1	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.08194183070207395	[955]	[911,953,609,885]	-1	hSpCas9	negative selection	6159966
33021076	33021099	2	-	27260156	CADOES1	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.18690398467279146	[386]	[406,416,376,438]	3	hSpCas9	negative selection	6224223
33021189	33021212	2	-	27260156	CADOES1	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.43235735831274735	[104]	[239,117,32,135]	7	hSpCas9	negative selection	6224224
33110709	33110732	2	-	27260156	CADOES1	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.12035870586142955	[621]	[729,589,463,734]	2	hSpCas9	negative selection	6224225
33188702	33188725	2	+	27260156	EWS502	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.04351414049986435	[731]	[1056,546,634,940]	0	hSpCas9	negative selection	6281215
33110630	33110653	2	-	27260156	EWS502	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.2998224394662494	[878]	[941,993,1151,1551]	5	hSpCas9	negative selection	6281216
33188779	33188802	2	+	27260156	EWS502	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.1588521473032285	[955]	[853,1219,1172,1313]	2	hSpCas9	negative selection	6281217
33021076	33021099	2	-	27260156	EWS502	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.11013811024888498	[386]	[283,408,551,552]	2	hSpCas9	negative selection	6345474
33021189	33021212	2	-	27260156	EWS502	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.4452135871163434	[104]	[61,67,83,117]	-6	hSpCas9	negative selection	6345475
33110709	33110732	2	-	27260156	EWS502	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.04969801638136895	[621]	[580,675,637,654]	-1	hSpCas9	negative selection	6345476
33188702	33188725	2	+	27260156	EW8	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.11764437852364262	[731]	[699,450,408,664]	-2	hSpCas9	negative selection	6402466
33110630	33110653	2	-	27260156	EW8	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.11007757480195846	[878]	[902,762,481,987]	2	hSpCas9	negative selection	6402467
33188779	33188802	2	+	27260156	EW8	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.045790969416317995	[955]	[966,830,522,741]	-1	hSpCas9	negative selection	6402468
33021076	33021099	2	-	27260156	EW8	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.14102694347825517	[386]	[365,265,259,257]	-3	hSpCas9	negative selection	6466725
33021189	33021212	2	-	27260156	EW8	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.28371526555674387	[104]	[123,88,116,83]	5	hSpCas9	negative selection	6466726
33110709	33110732	2	-	27260156	EW8	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.0629926519576009	[621]	[445,539,410,539]	-1	hSpCas9	negative selection	6466727
33188702	33188725	2	+	27260156	CORL105	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.2202649997054844	[731]	[998,970,1077,957]	4	hSpCas9	negative selection	6523717
33110630	33110653	2	-	27260156	CORL105	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.2365048876784943	[878]	[1157,1183,1241,1267]	4	hSpCas9	negative selection	6523718
33188779	33188802	2	+	27260156	CORL105	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.1428221776371179	[955]	[1328,1102,1380,1157]	2	hSpCas9	negative selection	6523719
33021076	33021099	2	-	27260156	CORL105	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.05717001206609024	[386]	[404,272,547,534]	-1	hSpCas9	negative selection	6587976
33021189	33021212	2	-	27260156	CORL105	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.5685770872987943	[104]	[56,85,79,106]	-7	hSpCas9	negative selection	6587977
33110709	33110732	2	-	27260156	CORL105	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.22494871110083864	[621]	[782,824,1015,803]	4	hSpCas9	negative selection	6587978
33188702	33188725	2	+	27260156	HS294T	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.8079694805398896	[731]	[527,440,454,566]	8	hSpCas9	negative selection	6644968
33110630	33110653	2	-	27260156	HS294T	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.006643081439120624	[878]	[302,382,293,395]	0	hSpCas9	negative selection	6644969
33188779	33188802	2	+	27260156	HS294T	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.5642578723905853	[955]	[375,534,650,657]	7	hSpCas9	negative selection	6644970
33021076	33021099	2	-	27260156	HS294T	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.11986003994006109	[386]	[227,143,104,167]	1	hSpCas9	negative selection	6709227
33021189	33021212	2	-	27260156	HS294T	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.9994437660559217	[104]	[22,10,12,36]	-8	hSpCas9	negative selection	6709228
33110709	33110732	2	-	27260156	HS294T	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.42912319026770956	[621]	[354,346,295,285]	6	hSpCas9	negative selection	6709229
33188702	33188725	2	+	27260156	HCC44	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.11734891560377891	[731]	[900,809,944,947]	1	hSpCas9	negative selection	6766219
33110630	33110653	2	-	27260156	HCC44	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.2960959228587987	[878]	[1262,1026,1519,1147]	5	hSpCas9	negative selection	6766220
33188779	33188802	2	+	27260156	HCC44	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.0988355066126958	[955]	[1234,883,1174,1369]	1	hSpCas9	negative selection	6766221
33021076	33021099	2	-	27260156	HCC44	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.24588860289499453	[386]	[556,426,622,499]	4	hSpCas9	negative selection	6830478
33021189	33021212	2	-	27260156	HCC44	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-1.2491634110814624	[104]	[41,44,59,53]	-9	hSpCas9	negative selection	6830479
33110709	33110732	2	-	27260156	HCC44	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.17580971615248286	[621]	[531,709,838,427]	-3	hSpCas9	negative selection	6830480
33188702	33188725	2	+	27260156	G402	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.32453436029963695	[731]	[787,534,841,686]	-4	hSpCas9	negative selection	6887470
33110630	33110653	2	-	27260156	G402	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	-0.05346918119101063	[878]	[1158,1206,1069,736]	0	hSpCas9	negative selection	6887471
33188779	33188802	2	+	27260156	G402	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.25518356823896826	[955]	[1925,1728,779,1232]	3	hSpCas9	negative selection	6887472
33021076	33021099	2	-	27260156	G402	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.10935185660323249	[386]	[353,398,388,847]	1	hSpCas9	negative selection	6951729
33021189	33021212	2	-	27260156	G402	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.6317055788557937	[104]	[59,89,39,134]	-7	hSpCas9	negative selection	6951730
33110709	33110732	2	-	27260156	G402	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.3094881470564265	[621]	[1097,832,901,941]	4	hSpCas9	negative selection	6951731
33188702	33188725	2	+	27260156	L33	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.254322167083321	[731]	[832,376,502,938]	5	hSpCas9	negative selection	7008721
33110630	33110653	2	-	27260156	L33	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	-0.03198881945206744	[878]	[885,369,512,832]	0	hSpCas9	negative selection	7008722
33188779	33188802	2	+	27260156	L33	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.5183890299786063	[955]	[1446,541,939,1211]	9	hSpCas9	negative selection	7008723
33021076	33021099	2	-	27260156	L33	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.31419451906848783	[386]	[311,116,208,314]	-6	hSpCas9	negative selection	7072980
33021189	33021212	2	-	27260156	L33	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.0959568280965244	[104]	[122,25,75,140]	2	hSpCas9	negative selection	7072981
33110709	33110732	2	-	27260156	L33	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.13361075403125183	[621]	[599,283,465,696]	3	hSpCas9	negative selection	7072982
33188702	33188725	2	+	27260156	K562	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.07171617853378898	[731]	[430,1064,760,262]	-1	hSpCas9	negative selection	7129972
33110630	33110653	2	-	27260156	K562	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.1890569100882038	[878]	[1026,885,767,883]	2	hSpCas9	negative selection	7129973
33188779	33188802	2	+	27260156	K562	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.06147706775186035	[955]	[1366,662,782,508]	-1	hSpCas9	negative selection	7129974
33021076	33021099	2	-	27260156	K562	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.10313821564420972	[386]	[120,206,518,398]	-1	hSpCas9	negative selection	7194231
33021189	33021212	2	-	27260156	K562	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-1.4723226674335508	[104]	[56,9,44,23]	-9	hSpCas9	negative selection	7194232
33110709	33110732	2	-	27260156	K562	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.5213105900559707	[621]	[859,1120,656,575]	6	hSpCas9	negative selection	7194233
33188702	33188725	2	+	27260156	HT29	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.09280920029904483	[731]	[957,917,890,1011]	1	hSpCas9	negative selection	7251223
33110630	33110653	2	-	27260156	HT29	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.09747382123128956	[878]	[1089,1374,1130,1001]	1	hSpCas9	negative selection	7251224
33188779	33188802	2	+	27260156	HT29	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.22540860758096715	[955]	[1250,1762,1283,1175]	4	hSpCas9	negative selection	7251225
33021076	33021099	2	-	27260156	HT29	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.06613237602759925	[386]	[582,435,430,363]	-1	hSpCas9	negative selection	7315482
33021189	33021212	2	-	27260156	HT29	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.9814387288352768	[104]	[81,46,37,87]	-8	hSpCas9	negative selection	7315483
33110709	33110732	2	-	27260156	HT29	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.2887882079716259	[621]	[889,1035,665,1082]	5	hSpCas9	negative selection	7315484
33188702	33188725	2	+	27260156	MHHES1	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.05474844485587316	[731]	[983,1084,922,529]	1	hSpCas9	negative selection	7372474
33110630	33110653	2	-	27260156	MHHES1	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	-0.0627920929588357	[878]	[841,1197,1183,633]	-1	hSpCas9	negative selection	7372475
33188779	33188802	2	+	27260156	MHHES1	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.0931293506776576	[955]	[1239,1682,766,979]	1	hSpCas9	negative selection	7372476
33021076	33021099	2	-	27260156	MHHES1	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.17636935441934742	[386]	[740,409,298,521]	3	hSpCas9	negative selection	7436733
33021189	33021212	2	-	27260156	MHHES1	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.4759497749161139	[104]	[87,134,23,93]	-7	hSpCas9	negative selection	7436734
33110709	33110732	2	-	27260156	MHHES1	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.13900816020692636	[621]	[714,664,1026,668]	2	hSpCas9	negative selection	7436735
33188702	33188725	2	+	27260156	MEWO	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.19552415671069434	[731]	[606,536,651]	-4	hSpCas9	negative selection	7493725
33110630	33110653	2	-	27260156	MEWO	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.12886797038426945	[878]	[1159,881,705]	3	hSpCas9	negative selection	7493726
33188779	33188802	2	+	27260156	MEWO	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.2469325132355782	[955]	[1023,982,1169]	5	hSpCas9	negative selection	7493727
33021076	33021099	2	-	27260156	MEWO	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.48472200113489455	[386]	[567,443,519]	8	hSpCas9	negative selection	7557984
33021189	33021212	2	-	27260156	MEWO	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.217972255836409	[104]	[57,131,57]	-5	hSpCas9	negative selection	7557985
33110709	33110732	2	-	27260156	MEWO	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.12959219517492349	[621]	[596,586,423]	-3	hSpCas9	negative selection	7557986
33188702	33188725	2	+	27260156	LNCAPCLONEFGC	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.1451166050427659	[731]	[677,653,821,797]	2	hSpCas9	negative selection	7614976
33110630	33110653	2	-	27260156	LNCAPCLONEFGC	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.26917184722237897	[878]	[1079,819,1036,918]	4	hSpCas9	negative selection	7614977
33188779	33188802	2	+	27260156	LNCAPCLONEFGC	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.10941110814388799	[955]	[1007,638,1261,893]	1	hSpCas9	negative selection	7614978
33021076	33021099	2	-	27260156	LNCAPCLONEFGC	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.259815386821314	[386]	[446,420,452,361]	4	hSpCas9	negative selection	7679235
33021189	33021212	2	-	27260156	LNCAPCLONEFGC	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.16975229896243804	[104]	[84,104,231,24]	2	hSpCas9	negative selection	7679236
33110709	33110732	2	-	27260156	LNCAPCLONEFGC	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.05969563803168443	[621]	[673,573,635,470]	0	hSpCas9	negative selection	7679237
33188702	33188725	2	+	27260156	PANC0327	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.2810490071141041	[731]	[900,1069,630,530]	4	hSpCas9	negative selection	7736227
33110630	33110653	2	-	27260156	PANC0327	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.32718897069619923	[878]	[1074,741,1209,929]	5	hSpCas9	negative selection	7736228
33188779	33188802	2	+	27260156	PANC0327	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.33812787691325297	[955]	[1246,1075,756,1226]	5	hSpCas9	negative selection	7736229
33021076	33021099	2	-	27260156	PANC0327	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.295346330395162	[386]	[338,418,467,454]	4	hSpCas9	negative selection	7800486
33021189	33021212	2	-	27260156	PANC0327	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.33214493393475397	[104]	[136,77,57,27]	-5	hSpCas9	negative selection	7800487
33110709	33110732	2	-	27260156	PANC0327	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.24322465098272744	[621]	[914,624,632,467]	3	hSpCas9	negative selection	7800488
33188702	33188725	2	+	27260156	NCIH2009	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.13069537346232352	[731]	[708,1062,981]	-2	hSpCas9	negative selection	7857478
33110630	33110653	2	-	27260156	NCIH2009	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.25854534593876854	[878]	[1838,1305,1335]	3	hSpCas9	negative selection	7857479
33188779	33188802	2	+	27260156	NCIH2009	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.5095769855153873	[955]	[2380,1686,1731]	7	hSpCas9	negative selection	7857480
33021076	33021099	2	-	27260156	NCIH2009	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.34117825144912184	[386]	[458,377,449]	-4	hSpCas9	negative selection	7921737
33021189	33021212	2	-	27260156	NCIH2009	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-1.1960958761771256	[104]	[113,55,31]	-8	hSpCas9	negative selection	7921738
33110709	33110732	2	-	27260156	NCIH2009	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.6177307851408682	[621]	[1515,1018,1504]	8	hSpCas9	negative selection	7921739
33188702	33188725	2	+	27260156	NCIH1373	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.17914500976867492	[731]	[500,860,765,187]	-2	hSpCas9	negative selection	7978729
33110630	33110653	2	-	27260156	NCIH1373	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.6438907141057963	[878]	[1409,1534,1406,471]	6	hSpCas9	negative selection	7978730
33188779	33188802	2	+	27260156	NCIH1373	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.07464282659852972	[955]	[1337,1204,706,341]	0	hSpCas9	negative selection	7978731
33021076	33021099	2	-	27260156	NCIH1373	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.30621051538476196	[386]	[282,378,489,261]	3	hSpCas9	negative selection	8042988
33021189	33021212	2	-	27260156	NCIH1373	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-1.081764149136876	[104]	[44,6,41,35]	-8	hSpCas9	negative selection	8042989
33110709	33110732	2	-	27260156	NCIH1373	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	1.274239355951784	[621]	[1551,1922,2241,239]	9	hSpCas9	negative selection	8042990
33188702	33188725	2	+	27260156	PATU8902	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.10027647513882465	[731]	[783,1129,1078,1415]	1	hSpCas9	negative selection	8099980
33110630	33110653	2	-	27260156	PATU8902	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.2063286748801494	[878]	[1355,1628,1234,1472]	2	hSpCas9	negative selection	8099981
33188779	33188802	2	+	27260156	PATU8902	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.12165670845786336	[955]	[966,1098,1260,1595]	-1	hSpCas9	negative selection	8099982
33021076	33021099	2	-	27260156	PATU8902	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.8398491994824931	[386]	[1146,637,993,1073]	8	hSpCas9	negative selection	8164239
33021189	33021212	2	-	27260156	PATU8902	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.2314781145133895	[104]	[148,88,89,184]	-2	hSpCas9	negative selection	8164240
33110709	33110732	2	-	27260156	PATU8902	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.34132836968610053	[621]	[1151,1013,952,1325]	3	hSpCas9	negative selection	8164241
33188702	33188725	2	+	27260156	PANC1	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.13341110678127477	[731]	[519,631,654,501]	-2	hSpCas9	negative selection	8221231
33110630	33110653	2	-	27260156	PANC1	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	-0.15168977517633742	[878]	[770,654,710,579]	-2	hSpCas9	negative selection	8221232
33188779	33188802	2	+	27260156	PANC1	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.48932882407649414	[955]	[992,1418,1183,1067]	7	hSpCas9	negative selection	8221233
33021076	33021099	2	-	27260156	PANC1	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.08470982529872365	[386]	[259,525,379,286]	1	hSpCas9	negative selection	8285490
33021189	33021212	2	-	27260156	PANC1	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.3858304706548017	[104]	[61,138,64,29]	-6	hSpCas9	negative selection	8285491
33110709	33110732	2	-	27260156	PANC1	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.11988617959232778	[621]	[499,881,506,499]	2	hSpCas9	negative selection	8285492
33188702	33188725	2	+	27260156	PANC0813	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.01203925350687618	[731]	[923,777,967,805]	0	hSpCas9	negative selection	8342482
33110630	33110653	2	-	27260156	PANC0813	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.15429181193830122	[878]	[1392,1252,953,1022]	2	hSpCas9	negative selection	8342483
33188779	33188802	2	+	27260156	PANC0813	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.42100290418557806	[955]	[1432,1366,1548,1647]	6	hSpCas9	negative selection	8342484
33021076	33021099	2	-	27260156	PANC0813	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.2877675966616451	[386]	[515,326,306,352]	-4	hSpCas9	negative selection	8406741
33021189	33021212	2	-	27260156	PANC0813	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.7449263077639228	[104]	[66,43,111,70]	-8	hSpCas9	negative selection	8406742
33110709	33110732	2	-	27260156	PANC0813	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.26531837376437856	[621]	[1080,878,725,844]	4	hSpCas9	negative selection	8406743
33188702	33188725	2	+	27260156	RDES	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.4032716957322228	[731]	[640,499,717,688]	-6	hSpCas9	negative selection	8463733
33110630	33110653	2	-	27260156	RDES	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.32214763564048776	[878]	[1048,1222,1304,1531]	5	hSpCas9	negative selection	8463734
33188779	33188802	2	+	27260156	RDES	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.0025241657623871205	[955]	[1013,1078,1044,1257]	0	hSpCas9	negative selection	8463735
33021076	33021099	2	-	27260156	RDES	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.208232664236302	[386]	[451,467,529,625]	3	hSpCas9	negative selection	8527992
33021189	33021212	2	-	27260156	RDES	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.001437175064324947	[104]	[85,170,101,122]	0	hSpCas9	negative selection	8527993
33110709	33110732	2	-	27260156	RDES	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.2173685205979356	[621]	[649,690,947,1113]	3	hSpCas9	negative selection	8527994
33188702	33188725	2	+	27260156	PC3	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.05755898802871273	[731]	[515,659,1089,693]	-1	hSpCas9	negative selection	8584984
33110630	33110653	2	-	27260156	PC3	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	-0.017941934050440422	[878]	[515,807,1320,1078]	0	hSpCas9	negative selection	8584985
33188779	33188802	2	+	27260156	PC3	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.15387585041743668	[955]	[671,893,1726,1293]	3	hSpCas9	negative selection	8584986
33021076	33021099	2	-	27260156	PC3	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.263432819355081	[386]	[259,488,594,611]	6	hSpCas9	negative selection	8649243
33021189	33021212	2	-	27260156	PC3	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.1312627207488326	[104]	[73,184,95,96]	3	hSpCas9	negative selection	8649244
33110709	33110732	2	-	27260156	PC3	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.17651872481206327	[621]	[537,737,1133,540]	4	hSpCas9	negative selection	8649245
33188702	33188725	2	+	27260156	PATU8988T	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.07290619522678954	[731]	[614,858,721,794]	1	hSpCas9	negative selection	8706235
33110630	33110653	2	-	27260156	PATU8988T	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.5012641179479909	[878]	[1381,1229,1177,1005]	8	hSpCas9	negative selection	8706236
33188779	33188802	2	+	27260156	PATU8988T	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.17052552805619592	[955]	[1190,957,884,1125]	3	hSpCas9	negative selection	8706237
33021076	33021099	2	-	27260156	PATU8988T	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.23288013578774094	[386]	[394,395,556,400]	4	hSpCas9	negative selection	8770494
33021189	33021212	2	-	27260156	PATU8988T	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.7839971026531076	[104]	[52,89,35,59]	-8	hSpCas9	negative selection	8770495
33110709	33110732	2	-	27260156	PATU8988T	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.058616187261243013	[621]	[733,665,468,437]	-1	hSpCas9	negative selection	8770496
33188702	33188725	2	+	27260156	T47D	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.04189409490479812	[731]	[816,794,758,949]	-1	hSpCas9	negative selection	8827486
33110630	33110653	2	-	27260156	T47D	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.12067076037222857	[878]	[1128,1304,1011,987]	2	hSpCas9	negative selection	8827487
33188779	33188802	2	+	27260156	T47D	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.12139064082632411	[955]	[1183,1092,1310,1267]	2	hSpCas9	negative selection	8827488
33021076	33021099	2	-	27260156	T47D	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.05152302746026566	[386]	[524,335,385,504]	-1	hSpCas9	negative selection	8891745
33021189	33021212	2	-	27260156	T47D	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.2735090368122344	[104]	[95,89,106,112]	-5	hSpCas9	negative selection	8891746
33110709	33110732	2	-	27260156	T47D	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.12537313066256367	[621]	[727,802,842,784]	2	hSpCas9	negative selection	8891747
33188702	33188725	2	+	27260156	SU8686	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.3387646656979669	[731]	[822,810,996,1087]	6	hSpCas9	negative selection	8948737
33110630	33110653	2	-	27260156	SU8686	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.13682881370831712	[878]	[932,701,1001,1277]	2	hSpCas9	negative selection	8948738
33188779	33188802	2	+	27260156	SU8686	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.47073743634280163	[955]	[1250,1113,1416,1533]	7	hSpCas9	negative selection	8948739
33021076	33021099	2	-	27260156	SU8686	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.023245573668242314	[386]	[419,295,464,385]	0	hSpCas9	negative selection	9012996
33021189	33021212	2	-	27260156	SU8686	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.4198710278069915	[104]	[95,62,44,110]	-6	hSpCas9	negative selection	9012997
33110709	33110732	2	-	27260156	SU8686	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.42495383060353714	[621]	[582,811,844,1147]	7	hSpCas9	negative selection	9012998
33188702	33188725	2	+	27260156	SKES1	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.1517761096130157	[731]	[1317,712,660,626]	3	hSpCas9	negative selection	9069988
33110630	33110653	2	-	27260156	SKES1	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.16842052298652388	[878]	[1273,1020,986,724]	3	hSpCas9	negative selection	9069989
33188779	33188802	2	+	27260156	SKES1	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.08558127428994466	[955]	[1087,1226,948,831]	1	hSpCas9	negative selection	9069990
33021076	33021099	2	-	27260156	SKES1	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.310886508395728	[386]	[421,538,616,345]	6	hSpCas9	negative selection	9134247
33021189	33021212	2	-	27260156	SKES1	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.5080723339818536	[104]	[46,44,119,73]	-8	hSpCas9	negative selection	9134248
33110709	33110732	2	-	27260156	SKES1	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.012035338366613413	[621]	[783,617,655,440]	0	hSpCas9	negative selection	9134249
33188702	33188725	2	+	27260156	TOV112D	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	0.008575688411929683	[731]	[642,859,585,877]	0	hSpCas9	negative selection	9191239
33110630	33110653	2	-	27260156	TOV112D	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.49527950233770146	[878]	[1215,1682,839,1326]	8	hSpCas9	negative selection	9191240
33188779	33188802	2	+	27260156	TOV112D	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.12671742127718555	[955]	[965,1458,843,1006]	2	hSpCas9	negative selection	9191241
33021076	33021099	2	-	27260156	TOV112D	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	0.35820485517792494	[386]	[434,905,424,320]	6	hSpCas9	negative selection	9255498
33021189	33021212	2	-	27260156	TOV112D	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.12818102690191457	[104]	[80,226,60,47]	-2	hSpCas9	negative selection	9255499
33110709	33110732	2	-	27260156	TOV112D	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.3171081863813081	[621]	[585,454,436,516]	-6	hSpCas9	negative selection	9255500
33188702	33188725	2	+	27260156	TC71	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.02669667889654148	[731]	[719,772,713,883]	0	hSpCas9	negative selection	9312490
33110630	33110653	2	-	27260156	TC71	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.19787087640626977	[878]	[1053,1119,1047,1103]	5	hSpCas9	negative selection	9312491
33188779	33188802	2	+	27260156	TC71	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	0.21151990993652192	[955]	[1013,1184,1124,1443]	5	hSpCas9	negative selection	9312492
33021076	33021099	2	-	27260156	TC71	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.0029341968283361775	[386]	[436,360,367,495]	0	hSpCas9	negative selection	9376749
33021189	33021212	2	-	27260156	TC71	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	-0.42533152038377153	[104]	[86,99,62,85]	-8	hSpCas9	negative selection	9376750
33110709	33110732	2	-	27260156	TC71	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	-0.022324973426961436	[621]	[581,732,602,714]	0	hSpCas9	negative selection	9376751
33188702	33188725	2	+	27260156	TC32	viability	CAATCCCAAGTCTCGTACCAAGG	LTBP1	ENSG00000049323	-0.28965486296833093	[731]	[419,480,780,625]	-5	hSpCas9	negative selection	9433741
33110630	33110653	2	-	27260156	TC32	viability	TGGGCTTGAGCACGTATTCCTGG	LTBP1	ENSG00000049323	0.2782325899255207	[878]	[1048,629,1256,1202]	5	hSpCas9	negative selection	9433742
33188779	33188802	2	+	27260156	TC32	viability	CATTCCTCACGTCTACCCCGTGG	LTBP1	ENSG00000049323	-0.11878530847814561	[955]	[703,603,1327,811]	-2	hSpCas9	negative selection	9433743
33021076	33021099	2	-	27260156	TC32	viability	GTATGCTTTGCTGCTTGCTCAGG	LTBP1	ENSG00000049323	-0.0438079567391777	[386]	[293,358,453,300]	0	hSpCas9	negative selection	9498000
33021189	33021212	2	-	27260156	TC32	viability	CTCACTGAGAATGTATCTGCTGG	LTBP1	ENSG00000049323	0.12703041169520013	[104]	[95,131,123,63]	2	hSpCas9	negative selection	9498001
33110709	33110732	2	-	27260156	TC32	viability	TGATCCTGCACATATCTTAAAGG	LTBP1	ENSG00000049323	0.25556724763226674	[621]	[619,514,913,824]	4	hSpCas9	negative selection	9498002
32947393	32947416	2	-	27869803	HPAFII	viability after 27 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.8612867958178976	[288]	[45,114,NaN]	-6	hSpCas9	negative selection	9574829
32948920	32948943	2	-	27869803	HPAFII	viability after 27 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.10850957511865333	[280]	[131,181,NaN]	0	hSpCas9	negative selection	9574830
33020914	33020937	2	+	27869803	HPAFII	viability after 27 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.41554054829146714	[568]	[320,463,NaN]	3	hSpCas9	negative selection	9574831
33110612	33110635	2	+	27869803	HPAFII	viability after 27 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.43115462825620465	[78]	[67,45,NaN]	3	hSpCas9	negative selection	9574832
33134775	33134798	2	-	27869803	HPAFII	viability after 27 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	-0.3636264518091207	[282]	[107,121,NaN]	-3	hSpCas9	negative selection	9574833
33187050	33187073	2	+	27869803	HPAFII	viability after 27 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.14246816899176995	[805]	[590,364,NaN]	1	hSpCas9	negative selection	9574834
32947393	32947416	2	-	27869803	HPAFII	viability after 15 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.3139825785912602	[288]	[247,250,NaN]	-4	hSpCas9	negative selection	9657278
32948920	32948943	2	-	27869803	HPAFII	viability after 15 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.17363429824013354	[280]	[413,294,NaN]	2	hSpCas9	negative selection	9657279
33020914	33020937	2	+	27869803	HPAFII	viability after 15 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.24661132427382038	[568]	[928,598,NaN]	3	hSpCas9	negative selection	9657280
33110612	33110635	2	+	27869803	HPAFII	viability after 15 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.576608068961125	[78]	[162,103,NaN]	6	hSpCas9	negative selection	9657281
33134775	33134798	2	-	27869803	HPAFII	viability after 15 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.47004858830883955	[282]	[350,464,NaN]	5	hSpCas9	negative selection	9657282
33187050	33187073	2	+	27869803	HPAFII	viability after 15 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.2924857120886408	[805]	[1412,841,NaN]	3	hSpCas9	negative selection	9657283
32947393	32947416	2	-	27869803	ASPC1	viability after 36 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.04596181691211719	[691]	[289,198,219]	0	hSpCas9	negative selection	9739727
32948920	32948943	2	-	27869803	ASPC1	viability after 36 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.054160845349837394	[788]	[454,298,153]	0	hSpCas9	negative selection	9739728
33020914	33020937	2	+	27869803	ASPC1	viability after 36 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.2155246525447594	[1354]	[545,573,525]	2	hSpCas9	negative selection	9739729
33110612	33110635	2	+	27869803	ASPC1	viability after 36 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	-0.35561309232306515	[246]	[32,114,52]	-4	hSpCas9	negative selection	9739730
33134775	33134798	2	-	27869803	ASPC1	viability after 36 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.6389994263841169	[632]	[419,196,403]	6	hSpCas9	negative selection	9739731
33187050	33187073	2	+	27869803	ASPC1	viability after 36 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.3214877147205404	[1823]	[1592,467,487]	3	hSpCas9	negative selection	9739732
32947393	32947416	2	-	27869803	PATU8988S	viability after 35 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.6194308779723143	[642]	[329,465,NaN]	6	hSpCas9	negative selection	9822176
32948920	32948943	2	-	27869803	PATU8988S	viability after 35 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.17058077788358905	[763]	[267,424,NaN]	2	hSpCas9	negative selection	9822177
33020914	33020937	2	+	27869803	PATU8988S	viability after 35 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.3019446579079914	[1095]	[621,465,NaN]	3	hSpCas9	negative selection	9822178
33110612	33110635	2	+	27869803	PATU8988S	viability after 35 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	1.7033896252145277	[184]	[307,176,NaN]	9	hSpCas9	negative selection	9822179
33134775	33134798	2	-	27869803	PATU8988S	viability after 35 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	-0.0700199173760439	[572]	[369,68,NaN]	0	hSpCas9	negative selection	9822180
33187050	33187073	2	+	27869803	PATU8988S	viability after 35 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.6083663262400012	[1620]	[1127,861,NaN]	6	hSpCas9	negative selection	9822181
32947393	32947416	2	-	27869803	PATU8988S	viability after 31 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	0.9251536817351135	[642]	[386,613,NaN]	9	hSpCas9	negative selection	9904625
32948920	32948943	2	-	27869803	PATU8988S	viability after 31 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	0.3374555667635535	[763]	[387,380,NaN]	4	hSpCas9	negative selection	9904626
33020914	33020937	2	+	27869803	PATU8988S	viability after 31 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.28304096449226623	[1095]	[485,589,NaN]	3	hSpCas9	negative selection	9904627
33110612	33110635	2	+	27869803	PATU8988S	viability after 31 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	1.6762725421170923	[184]	[244,223,NaN]	9	hSpCas9	negative selection	9904628
33134775	33134798	2	-	27869803	PATU8988S	viability after 31 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	-0.273924060649121	[572]	[228,137,NaN]	-3	hSpCas9	negative selection	9904629
33187050	33187073	2	+	27869803	PATU8988S	viability after 31 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	0.47792164805994175	[1620]	[769,1065,NaN]	6	hSpCas9	negative selection	9904630
32947393	32947416	2	-	27869803	HPAFII	viability after 35 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.6119194596166228	[288]	[27,171,NaN]	-4	hSpCas9	negative selection	9987074
32948920	32948943	2	-	27869803	HPAFII	viability after 35 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	-0.381540053136054	[280]	[32,194,NaN]	-2	hSpCas9	negative selection	9987075
33020914	33020937	2	+	27869803	HPAFII	viability after 35 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.6296548149991412	[568]	[265,647,NaN]	4	hSpCas9	negative selection	9987076
33110612	33110635	2	+	27869803	HPAFII	viability after 35 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	1.3000990872116824	[78]	[121,71,NaN]	8	hSpCas9	negative selection	9987077
33134775	33134798	2	-	27869803	HPAFII	viability after 35 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	0.37977401503609187	[282]	[65,321,NaN]	2	hSpCas9	negative selection	9987078
33187050	33187073	2	+	27869803	HPAFII	viability after 35 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	-0.19313463670241826	[805]	[291,429,NaN]	-1	hSpCas9	negative selection	9987079
32947393	32947416	2	-	27869803	HPAFII	viability after 31 days	CGTAGGTGATCCTCCGCAGCCGG	LTBP1	ENSG00000049323	-0.5499264338469343	[288]	[38,188,NaN]	-4	hSpCas9	negative selection	10069523
32948920	32948943	2	-	27869803	HPAFII	viability after 31 days	TGGTGCACCTCTGGGAGCCAGGG	LTBP1	ENSG00000049323	-0.5450230764412587	[280]	[109,105,NaN]	-4	hSpCas9	negative selection	10069524
33020914	33020937	2	+	27869803	HPAFII	viability after 31 days	TGTGTTCCGCCATGTCAGAATGG	LTBP1	ENSG00000049323	0.5884491865577532	[568]	[371,597,NaN]	4	hSpCas9	negative selection	10069525
33110612	33110635	2	+	27869803	HPAFII	viability after 31 days	GATTCACCATGGCCAGACCCAGG	LTBP1	ENSG00000049323	0.7063691239815295	[78]	[79,63,NaN]	5	hSpCas9	negative selection	10069526
33134775	33134798	2	-	27869803	HPAFII	viability after 31 days	ACTCACTAGGAGCGGAGGCAGGG	LTBP1	ENSG00000049323	-0.626788868884554	[282]	[54,154,NaN]	-4	hSpCas9	negative selection	10069527
33187050	33187073	2	+	27869803	HPAFII	viability after 31 days	CTGACCGTGACTAGCCAGCAAGG	LTBP1	ENSG00000049323	-0.052678760939528946	[805]	[449,420,NaN]	0	hSpCas9	negative selection	10069528
33275005	33275028	2	+	28162770	P31FUJ	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.5192702821420359	[94]	[159]	6	hSpCas9	negative selection	10186962
33188767	33188790	2	-	28162770	P31FUJ	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.5002589352959115	[517]	[860]	5	hSpCas9	negative selection	10186963
33217610	33217633	2	-	28162770	P31FUJ	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.9371227970279337	[87]	[197]	9	hSpCas9	negative selection	10186964
33262770	33262793	2	-	28162770	P31FUJ	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-1.5399837139325545	[145]	[58]	-7	hSpCas9	negative selection	10186965
33263317	33263340	2	-	28162770	P31FUJ	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	-0.3497199561935295	[166]	[153]	-3	hSpCas9	negative selection	10186966
33360714	33360737	2	+	28162770	P31FUJ	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.7929353569992298	[249]	[508]	8	hSpCas9	negative selection	10186967
33389197	33389220	2	+	28162770	P31FUJ	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.6294021987420904	[493]	[897]	7	hSpCas9	negative selection	10186968
33134800	33134823	2	+	28162770	P31FUJ	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.08405490092556196	[227]	[283]	0	hSpCas9	negative selection	10186969
33134809	33134832	2	-	28162770	P31FUJ	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.15635014397650537	[440]	[464]	-1	hSpCas9	negative selection	10186970
33186992	33187015	2	+	28162770	P31FUJ	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	0.441427634403865	[46]	[74]	5	hSpCas9	negative selection	10186971
33275005	33275028	2	+	28162770	TF1	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	NaN	[NaN]	[114]	1	hSpCas9	negative selection	10356328
33188767	33188790	2	-	28162770	TF1	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	NaN	[NaN]	[573]	1	hSpCas9	negative selection	10356329
33217610	33217633	2	-	28162770	TF1	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	NaN	[NaN]	[90]	1	hSpCas9	negative selection	10356330
33262770	33262793	2	-	28162770	TF1	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	NaN	[NaN]	[55]	1	hSpCas9	negative selection	10356331
33263317	33263340	2	-	28162770	TF1	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	NaN	[NaN]	[122]	1	hSpCas9	negative selection	10356332
33360714	33360737	2	+	28162770	TF1	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	NaN	[NaN]	[242]	1	hSpCas9	negative selection	10356333
33389197	33389220	2	+	28162770	TF1	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	NaN	[NaN]	[482]	1	hSpCas9	negative selection	10356334
33134800	33134823	2	+	28162770	TF1	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	NaN	[NaN]	[136]	1	hSpCas9	negative selection	10356335
33134809	33134832	2	-	28162770	TF1	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	NaN	[NaN]	[268]	1	hSpCas9	negative selection	10356336
33186992	33187015	2	+	28162770	TF1	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	NaN	[NaN]	[51]	1	hSpCas9	negative selection	10356337
33275005	33275028	2	+	28162770	SKM1	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	-0.020547377404085743	[34]	[60]	0	hSpCas9	negative selection	10525694
33188767	33188790	2	-	28162770	SKM1	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.4003907233144426	[104]	[244]	4	hSpCas9	negative selection	10525695
33217610	33217633	2	-	28162770	SKM1	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.5565099252317243	[24]	[64]	5	hSpCas9	negative selection	10525696
33262770	33262793	2	-	28162770	SKM1	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	0.21647244979263014	[36]	[75]	2	hSpCas9	negative selection	10525697
33263317	33263340	2	-	28162770	SKM1	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	1.0524674198941355	[35]	[131]	8	hSpCas9	negative selection	10525698
33360714	33360737	2	+	28162770	SKM1	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.8116346494348405	[67]	[210]	7	hSpCas9	negative selection	10525699
33389197	33389220	2	+	28162770	SKM1	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.7291130322154777	[114]	[336]	7	hSpCas9	negative selection	10525700
33134800	33134823	2	+	28162770	SKM1	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	1.2130452490771952	[60]	[249]	9	hSpCas9	negative selection	10525701
33134809	33134832	2	-	28162770	SKM1	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.3704383227180479	[116]	[159]	-3	hSpCas9	negative selection	10525702
33186992	33187015	2	+	28162770	SKM1	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	0.00112053989391514	[12]	[22]	0	hSpCas9	negative selection	10525703
33275005	33275028	2	+	28162770	SKM1	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	-0.020547377404085743	[34]	[60]	0	hSpCas9	negative selection	10695060
33188767	33188790	2	-	28162770	SKM1	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.4003907233144426	[104]	[244]	4	hSpCas9	negative selection	10695061
33217610	33217633	2	-	28162770	SKM1	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.5565099252317243	[24]	[64]	5	hSpCas9	negative selection	10695062
33262770	33262793	2	-	28162770	SKM1	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	0.21647244979263014	[36]	[75]	2	hSpCas9	negative selection	10695063
33263317	33263340	2	-	28162770	SKM1	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	1.0524674198941355	[35]	[131]	8	hSpCas9	negative selection	10695064
33360714	33360737	2	+	28162770	SKM1	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.8116346494348405	[67]	[210]	7	hSpCas9	negative selection	10695065
33389197	33389220	2	+	28162770	SKM1	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.7291130322154777	[114]	[336]	7	hSpCas9	negative selection	10695066
33134800	33134823	2	+	28162770	SKM1	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	1.2130452490771952	[60]	[249]	9	hSpCas9	negative selection	10695067
33134809	33134832	2	-	28162770	SKM1	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.3704383227180479	[116]	[159]	-3	hSpCas9	negative selection	10695068
33186992	33187015	2	+	28162770	SKM1	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	0.00112053989391514	[12]	[22]	0	hSpCas9	negative selection	10695069
33275005	33275028	2	+	28162770	PL21	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	2.032682868637757	[72]	[129]	9	hSpCas9	negative selection	10864426
33188767	33188790	2	-	28162770	PL21	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.34547897765335933	[433]	[239]	3	hSpCas9	negative selection	10864427
33217610	33217633	2	-	28162770	PL21	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	-0.48058186903726685	[108]	[33]	-3	hSpCas9	negative selection	10864428
33262770	33262793	2	-	28162770	PL21	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-0.48367627315812134	[150]	[46]	-3	hSpCas9	negative selection	10864429
33263317	33263340	2	-	28162770	PL21	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.3678670602273865	[145]	[81]	3	hSpCas9	negative selection	10864430
33360714	33360737	2	+	28162770	PL21	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.687585609296214	[203]	[142]	6	hSpCas9	negative selection	10864431
33389197	33389220	2	+	28162770	PL21	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	-0.21713635698552314	[429]	[160]	-1	hSpCas9	negative selection	10864432
33134800	33134823	2	+	28162770	PL21	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.43208634253901695	[171]	[100]	4	hSpCas9	negative selection	10864433
33134809	33134832	2	-	28162770	PL21	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	0.6412149746696875	[301]	[204]	5	hSpCas9	negative selection	10864434
33186992	33187015	2	+	28162770	PL21	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	-0.08936700270566478	[21]	[8]	0	hSpCas9	negative selection	10864435
33275005	33275028	2	+	28162770	P31FUJ	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.5192702821420359	[94]	[159]	6	hSpCas9	negative selection	11033792
33188767	33188790	2	-	28162770	P31FUJ	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.5002589352959115	[517]	[860]	5	hSpCas9	negative selection	11033793
33217610	33217633	2	-	28162770	P31FUJ	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.9371227970279337	[87]	[197]	9	hSpCas9	negative selection	11033794
33262770	33262793	2	-	28162770	P31FUJ	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-1.5399837139325545	[145]	[58]	-7	hSpCas9	negative selection	11033795
33263317	33263340	2	-	28162770	P31FUJ	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	-0.3497199561935295	[166]	[153]	-3	hSpCas9	negative selection	11033796
33360714	33360737	2	+	28162770	P31FUJ	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.7929353569992298	[249]	[508]	8	hSpCas9	negative selection	11033797
33389197	33389220	2	+	28162770	P31FUJ	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.6294021987420904	[493]	[897]	7	hSpCas9	negative selection	11033798
33134800	33134823	2	+	28162770	P31FUJ	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.08405490092556196	[227]	[283]	0	hSpCas9	negative selection	11033799
33134809	33134832	2	-	28162770	P31FUJ	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.15635014397650537	[440]	[464]	-1	hSpCas9	negative selection	11033800
33186992	33187015	2	+	28162770	P31FUJ	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	0.441427634403865	[46]	[74]	5	hSpCas9	negative selection	11033801
33275005	33275028	2	+	28162770	OCIAML5	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	-0.5231180482988625	[81]	[102]	-4	hSpCas9	negative selection	11203158
33188767	33188790	2	-	28162770	OCIAML5	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.3640858102906117	[330]	[768]	3	hSpCas9	negative selection	11203159
33217610	33217633	2	-	28162770	OCIAML5	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	-0.5550848331068655	[69]	[85]	-4	hSpCas9	negative selection	11203160
33262770	33262793	2	-	28162770	OCIAML5	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-1.8520665708639967	[59]	[29]	-7	hSpCas9	negative selection	11203161
33263317	33263340	2	-	28162770	OCIAML5	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	-0.4146612585566986	[95]	[129]	-3	hSpCas9	negative selection	11203162
33360714	33360737	2	+	28162770	OCIAML5	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.7328959298571592	[124]	[374]	6	hSpCas9	negative selection	11203163
33389197	33389220	2	+	28162770	OCIAML5	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	-0.030454569243941965	[373]	[660]	0	hSpCas9	negative selection	11203164
33134800	33134823	2	+	28162770	OCIAML5	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.5455257939554375	[155]	[410]	5	hSpCas9	negative selection	11203165
33134809	33134832	2	-	28162770	OCIAML5	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.7330593907314514	[313]	[340]	-5	hSpCas9	negative selection	11203166
33186992	33187015	2	+	28162770	OCIAML5	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	0.8911580137738917	[22]	[76]	7	hSpCas9	negative selection	11203167
33275005	33275028	2	+	28162770	EOL1	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.46886828779434475	[143]	[104]	4	hSpCas9	negative selection	11372524
33188767	33188790	2	-	28162770	EOL1	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	-0.2089930793775887	[508]	[231]	-1	hSpCas9	negative selection	11372525
33217610	33217633	2	-	28162770	EOL1	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.8578216577697215	[176]	[168]	7	hSpCas9	negative selection	11372526
33262770	33262793	2	-	28162770	EOL1	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-0.7635082221147252	[260]	[80]	-5	hSpCas9	negative selection	11372527
33263317	33263340	2	-	28162770	EOL1	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.283385132078913	[300]	[192]	2	hSpCas9	negative selection	11372528
33360714	33360737	2	+	28162770	EOL1	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.7416837144207241	[461]	[406]	6	hSpCas9	negative selection	11372529
33389197	33389220	2	+	28162770	EOL1	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	-0.14325221364392526	[500]	[238]	-1	hSpCas9	negative selection	11372530
33134800	33134823	2	+	28162770	EOL1	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	-0.1550693964928334	[297]	[140]	-1	hSpCas9	negative selection	11372531
33134809	33134832	2	-	28162770	EOL1	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	0.9141311556251962	[555]	[551]	7	hSpCas9	negative selection	11372532
33186992	33187015	2	+	28162770	EOL1	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	0.8156134000173703	[54]	[50]	7	hSpCas9	negative selection	11372533
33275005	33275028	2	+	28162770	MOLM13	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	1.0281898280314656	[117]	[173]	7	hSpCas9	negative selection	11541890
33188767	33188790	2	-	28162770	MOLM13	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.9309740552305313	[501]	[691]	7	hSpCas9	negative selection	11541891
33217610	33217633	2	-	28162770	MOLM13	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.6026387936578164	[142]	[156]	4	hSpCas9	negative selection	11541892
33262770	33262793	2	-	28162770	MOLM13	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-1.1170731191765775	[200]	[66]	-5	hSpCas9	negative selection	11541893
33263317	33263340	2	-	28162770	MOLM13	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.9133921615504736	[245]	[334]	7	hSpCas9	negative selection	11541894
33360714	33360737	2	+	28162770	MOLM13	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	1.7078401742653313	[314]	[743]	9	hSpCas9	negative selection	11541895
33389197	33389220	2	+	28162770	MOLM13	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.45026845970216245	[658]	[650]	3	hSpCas9	negative selection	11541896
33134800	33134823	2	+	28162770	MOLM13	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.08754460043189452	[314]	[241]	0	hSpCas9	negative selection	11541897
33134809	33134832	2	-	28162770	MOLM13	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.4215137873350987	[614]	[331]	-3	hSpCas9	negative selection	11541898
33186992	33187015	2	+	28162770	MOLM13	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	1.962654073294157	[32]	[92]	9	hSpCas9	negative selection	11541899
33275005	33275028	2	+	28162770	HEL	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.5938292315194105	[119]	[115]	5	hSpCas9	negative selection	11711256
33188767	33188790	2	-	28162770	HEL	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.6635830857932014	[480]	[487]	5	hSpCas9	negative selection	11711257
33217610	33217633	2	-	28162770	HEL	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.4668889966009393	[121]	[107]	4	hSpCas9	negative selection	11711258
33262770	33262793	2	-	28162770	HEL	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-2.4762022407231505	[138]	[15]	-8	hSpCas9	negative selection	11711259
33263317	33263340	2	-	28162770	HEL	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.773046854346088	[200]	[219]	6	hSpCas9	negative selection	11711260
33360714	33360737	2	+	28162770	HEL	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.8082041852519695	[287]	[322]	7	hSpCas9	negative selection	11711261
33389197	33389220	2	+	28162770	HEL	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	-0.36537381378696276	[534]	[265]	-3	hSpCas9	negative selection	11711262
33134800	33134823	2	+	28162770	HEL	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	-0.1750578367788941	[207]	[117]	-1	hSpCas9	negative selection	11711263
33134809	33134832	2	-	28162770	HEL	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	0.023714495205567787	[449]	[292]	0	hSpCas9	negative selection	11711264
33186992	33187015	2	+	28162770	HEL	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	-0.3572611679996429	[31]	[15]	-2	hSpCas9	negative selection	11711265
33275005	33275028	2	+	28162770	MV411	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.4400826287251711	[111]	[127]	4	hSpCas9	negative selection	11880622
33188767	33188790	2	-	28162770	MV411	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.7371138509543749	[338]	[475]	6	hSpCas9	negative selection	11880623
33217610	33217633	2	-	28162770	MV411	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	-0.3556722966486404	[119]	[78]	-3	hSpCas9	negative selection	11880624
33262770	33262793	2	-	28162770	MV411	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	0.060559416059265736	[106]	[93]	0	hSpCas9	negative selection	11880625
33263317	33263340	2	-	28162770	MV411	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.6807869283385608	[136]	[184]	6	hSpCas9	negative selection	11880626
33360714	33360737	2	+	28162770	MV411	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.9373348912922026	[242]	[391]	8	hSpCas9	negative selection	11880627
33389197	33389220	2	+	28162770	MV411	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	-0.23869492327895658	[408]	[291]	-2	hSpCas9	negative selection	11880628
33134800	33134823	2	+	28162770	MV411	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	-0.28638610094657996	[193]	[133]	-2	hSpCas9	negative selection	11880629
33134809	33134832	2	-	28162770	MV411	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.23967762654023628	[341]	[243]	-2	hSpCas9	negative selection	11880630
33186992	33187015	2	+	28162770	MV411	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	1.0273117364182722	[52]	[90]	8	hSpCas9	negative selection	11880631
33275005	33275028	2	+	28162770	MONOMAC1	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.5861517638672982	[42]	[73]	6	hSpCas9	negative selection	12049988
33188767	33188790	2	-	28162770	MONOMAC1	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	-0.4827447540341627	[294]	[241]	-4	hSpCas9	negative selection	12049989
33217610	33217633	2	-	28162770	MONOMAC1	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.4403930735557382	[71]	[111]	4	hSpCas9	negative selection	12049990
33262770	33262793	2	-	28162770	MONOMAC1	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-0.29756372301351824	[103]	[96]	-3	hSpCas9	negative selection	12049991
33263317	33263340	2	-	28162770	MONOMAC1	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.13343635696081735	[100]	[126]	1	hSpCas9	negative selection	12049992
33360714	33360737	2	+	28162770	MONOMAC1	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	-0.06077115696847257	[211]	[232]	0	hSpCas9	negative selection	12049993
33389197	33389220	2	+	28162770	MONOMAC1	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.41398795024779833	[255]	[390]	4	hSpCas9	negative selection	12049994
33134800	33134823	2	+	28162770	MONOMAC1	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	-1.0043917691171578	[146]	[83]	-7	hSpCas9	negative selection	12049995
33134809	33134832	2	-	28162770	MONOMAC1	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	0.44769787417897144	[196]	[307]	4	hSpCas9	negative selection	12049996
33186992	33187015	2	+	28162770	MONOMAC1	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	-0.711610019889312	[39]	[27]	-5	hSpCas9	negative selection	12049997
33275005	33275028	2	+	28162770	OCIAML2	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	1.2356389717011285	[18]	[247]	9	hSpCas9	negative selection	12219354
33188767	33188790	2	-	28162770	OCIAML2	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.44584681919555536	[79]	[603]	4	hSpCas9	negative selection	12219355
33217610	33217633	2	-	28162770	OCIAML2	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.27532455215129964	[23]	[160]	2	hSpCas9	negative selection	12219356
33262770	33262793	2	-	28162770	OCIAML2	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-1.83986363490788	[30]	[47]	-8	hSpCas9	negative selection	12219357
33263317	33263340	2	-	28162770	OCIAML2	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	0.22285713225716403	[31]	[206]	2	hSpCas9	negative selection	12219358
33360714	33360737	2	+	28162770	OCIAML2	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.5213328556924204	[44]	[357]	5	hSpCas9	negative selection	12219359
33389197	33389220	2	+	28162770	OCIAML2	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	0.4434205619392234	[66]	[504]	4	hSpCas9	negative selection	12219360
33134800	33134823	2	+	28162770	OCIAML2	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	-0.2482374039057133	[41]	[195]	-2	hSpCas9	negative selection	12219361
33134809	33134832	2	-	28162770	OCIAML2	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	0.0893657599624198	[67]	[400]	0	hSpCas9	negative selection	12219362
33186992	33187015	2	+	28162770	OCIAML2	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	1.1143326754789948	[6]	[83]	9	hSpCas9	negative selection	12219363
33275005	33275028	2	+	28162770	OCIAML3	viability	GGGCCGCTGTGAAAACACCGAGG	LTBP1	ENSG00000049323	0.30411274565662344	[32]	[122]	3	hSpCas9	negative selection	12388720
33188767	33188790	2	-	28162770	OCIAML3	viability	CGTGAGGAATGACCTGCTGGTGG	LTBP1	ENSG00000049323	0.4620263945901647	[100]	[419]	4	hSpCas9	negative selection	12388721
33217610	33217633	2	-	28162770	OCIAML3	viability	GCATTTGTTAAAGCCCCAGGAGG	LTBP1	ENSG00000049323	0.5635336366623167	[25]	[115]	5	hSpCas9	negative selection	12388722
33262770	33262793	2	-	28162770	OCIAML3	viability	GAAATGCCTGGAGACAGCTGGGG	LTBP1	ENSG00000049323	-0.39237377915451255	[29]	[68]	-3	hSpCas9	negative selection	12388723
33263317	33263340	2	-	28162770	OCIAML3	viability	GGAGCTACTTCAACAGGCACAGG	LTBP1	ENSG00000049323	-0.3446481713874459	[52]	[125]	-3	hSpCas9	negative selection	12388724
33360714	33360737	2	+	28162770	OCIAML3	viability	GCTGTACATCAGGCGTGGGATGG	LTBP1	ENSG00000049323	0.06812272091945293	[90]	[287]	0	hSpCas9	negative selection	12388725
33389197	33389220	2	+	28162770	OCIAML3	viability	GCTGTGTAACATCCCCGTGACGG	LTBP1	ENSG00000049323	-0.3879354726740811	[126]	[292]	-3	hSpCas9	negative selection	12388726
33134800	33134823	2	+	28162770	OCIAML3	viability	CCACACTGGCCGCATCAAGGTGG	LTBP1	ENSG00000049323	0.309562596992744	[57]	[216]	3	hSpCas9	negative selection	12388727
33134809	33134832	2	-	28162770	OCIAML3	viability	GAGTAAAGACCACCTTGATGCGG	LTBP1	ENSG00000049323	-0.2996771040008308	[94]	[232]	-2	hSpCas9	negative selection	12388728
33186992	33187015	2	+	28162770	OCIAML3	viability	CCAGCAGCCAGGCAAGGCGTTGG	LTBP1	ENSG00000049323	-0.40136256238176715	[13]	[31]	-3	hSpCas9	negative selection	12388729