Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4053
• Symbol:LTBP2
• Description:latent transforming growth factor beta binding protein 2

DataSource: http://genomecrispr.dkfz.de/#!/results/LTBP2

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
74585842	74585865	14	+	26472758	Jiyoye	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.03642715837182631	[277]	[214]	0	hSpCas9	negative selection	93857
74611875	74611898	14	+	26472758	Jiyoye	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.7057186749000599	[92]	[42]	-5	hSpCas9	negative selection	93858
74586088	74586111	14	-	26472758	Jiyoye	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	1.1727101278688505	[189]	[322]	7	hSpCas9	negative selection	93859
74586052	74586075	14	+	26472758	Jiyoye	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-2.381320513300415	[75]	[10]	-8	hSpCas9	negative selection	93860
74586035	74586058	14	+	26472758	Jiyoye	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	-0.07825144566436837	[34]	[24]	0	hSpCas9	negative selection	93861
74586014	74586037	14	+	26472758	Jiyoye	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	-0.525009234266555	[186]	[97]	-4	hSpCas9	negative selection	93862
74585842	74585865	14	+	26472758	KBM7	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.4534084733795003	[1161,606]	[620,493]	5	hSpCas9	negative selection	284975
74611875	74611898	14	+	26472758	KBM7	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-1.6264700259791638	[465,252]	[74,33]	-8	hSpCas9	negative selection	284976
74586088	74586111	14	-	26472758	KBM7	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.11056551827049843	[1100,754]	[522,411]	1	hSpCas9	negative selection	284977
74586052	74586075	14	+	26472758	KBM7	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-0.9785507665487347	[238,128]	[46,38]	-6	hSpCas9	negative selection	284978
74586035	74586058	14	+	26472758	KBM7	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	-0.986459755552433	[131,125]	[45,16]	-6	hSpCas9	negative selection	284979
74586014	74586037	14	+	26472758	KBM7	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.06022572840650764	[812,402]	[265,309]	0	hSpCas9	negative selection	284980
74585842	74585865	14	+	26472758	Raji	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.011683118953013993	[482]	[112]	0	hSpCas9	negative selection	476093
74611875	74611898	14	+	26472758	Raji	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-1.4455888511031199	[222]	[18]	-7	hSpCas9	negative selection	476094
74586088	74586111	14	-	26472758	Raji	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.6703197297647566	[351]	[129]	6	hSpCas9	negative selection	476095
74586052	74586075	14	+	26472758	Raji	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-2.682693395252169	[82]	[2]	-9	hSpCas9	negative selection	476096
74586035	74586058	14	+	26472758	Raji	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	-1.0852615425687964	[127]	[13]	-7	hSpCas9	negative selection	476097
74586014	74586037	14	+	26472758	Raji	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	-0.13877705189579814	[407]	[85]	-1	hSpCas9	negative selection	476098
74585842	74585865	14	+	26472758	K562	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.1690025827002164	[804]	[763]	1	hSpCas9	negative selection	667211
74611875	74611898	14	+	26472758	K562	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-1.852878473688468	[367]	[85]	-7	hSpCas9	negative selection	667212
74586088	74586111	14	-	26472758	K562	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	1.1050967099023796	[515]	[936]	8	hSpCas9	negative selection	667213
74586052	74586075	14	+	26472758	K562	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-3.4336531774461907	[191]	[14]	-8	hSpCas9	negative selection	667214
74586035	74586058	14	+	26472758	K562	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	0.36281342846867703	[151]	[164]	3	hSpCas9	negative selection	667215
74586014	74586037	14	+	26472758	K562	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.458641846082189	[505]	[586]	3	hSpCas9	negative selection	667216
74586096	74586119	14	+	26627737	DLD1	viability	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	-0.14478097522899924	[778]	[226,227,207]	-1	hSpCas9	negative selection	789363
74603626	74603649	14	+	26627737	DLD1	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.861755176610518	[384]	[161,232,255]	8	hSpCas9	negative selection	789364
74611848	74611871	14	-	26627737	DLD1	viability	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	1.3628893604695582	[182]	[210,106,124]	9	hSpCas9	negative selection	789365
74586096	74586119	14	+	26627737	GBM cells	viability after 5 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.1345977925745242	[354]	[230,186]	2	hSpCas9	negative selection	871678
74603626	74603649	14	+	26627737	GBM cells	viability after 5 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.247250972957012	[248]	[174,141]	4	hSpCas9	negative selection	871679
74611848	74611871	14	-	26627737	GBM cells	viability after 5 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	-0.22809140184963483	[177]	[78,83]	-4	hSpCas9	negative selection	871680
74586096	74586119	14	+	26627737	GBM cells	viability after 13 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.10545144691500752	[354]	[236,182]	1	hSpCas9	negative selection	953993
74603626	74603649	14	+	26627737	GBM cells	viability after 13 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.4200704018529893	[248]	[193,169]	5	hSpCas9	negative selection	953994
74611848	74611871	14	-	26627737	GBM cells	viability after 13 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	-0.22448204906337121	[177]	[96,70]	-3	hSpCas9	negative selection	953995
74586096	74586119	14	+	26627737	GBM cells	viability after 21 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	-0.2672113535958926	[354]	[165,154]	-2	hSpCas9	negative selection	1036308
74603626	74603649	14	+	26627737	GBM cells	viability after 21 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.749742703257349	[248]	[239,215]	7	hSpCas9	negative selection	1036309
74611848	74611871	14	-	26627737	GBM cells	viability after 21 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	-0.5284542465337118	[177]	[65,67]	-5	hSpCas9	negative selection	1036310
74586096	74586119	14	+	26627737	RPE1	viability after 9 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	-0.0646053038252139	[1170]	[188,558]	0	hSpCas9	negative selection	1118623
74603626	74603649	14	+	26627737	RPE1	viability after 9 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.2282959780348432	[1053]	[379,394]	1	hSpCas9	negative selection	1118624
74611848	74611871	14	-	26627737	RPE1	viability after 9 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.39119288186696477	[818]	[313,364]	2	hSpCas9	negative selection	1118625
74586096	74586119	14	+	26627737	RPE1	viability after 12 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.07003200560766232	[1170]	[321,338]	0	hSpCas9	negative selection	1200938
74603626	74603649	14	+	26627737	RPE1	viability after 12 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.025569130309199883	[1053]	[352,198]	0	hSpCas9	negative selection	1200939
74611848	74611871	14	-	26627737	RPE1	viability after 12 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.6557574473158426	[818]	[402,286]	4	hSpCas9	negative selection	1200940
74586096	74586119	14	+	26627737	RPE1	viability after 15 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.4095461353284232	[1170]	[524,357]	2	hSpCas9	negative selection	1283253
74603626	74603649	14	+	26627737	RPE1	viability after 15 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.485589197435985	[1053]	[503,333]	3	hSpCas9	negative selection	1283254
74611848	74611871	14	-	26627737	RPE1	viability after 15 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.28246900214888526	[818]	[293,269]	1	hSpCas9	negative selection	1283255
74586096	74586119	14	+	26627737	RPE1	viability after 18 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	-0.4796297795086677	[1170]	[215,237]	-3	hSpCas9	negative selection	1365568
74603626	74603649	14	+	26627737	RPE1	viability after 18 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.20822690904211466	[1053]	[287,371]	1	hSpCas9	negative selection	1365569
74611848	74611871	14	-	26627737	RPE1	viability after 18 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.7193111593494025	[818]	[418,304]	4	hSpCas9	negative selection	1365570
74586096	74586119	14	+	26627737	HeLa	viability after 8 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.3575029335440084	[606]	[339,328,345]	3	hSpCas9	negative selection	1447883
74603626	74603649	14	+	26627737	HeLa	viability after 8 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.28219675232692976	[575]	[287,225,127]	-3	hSpCas9	negative selection	1447884
74611848	74611871	14	-	26627737	HeLa	viability after 8 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.8096226645891693	[303]	[253,296,154]	6	hSpCas9	negative selection	1447885
74586096	74586119	14	+	26627737	HeLa	viability after 12 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.13685421067772452	[606]	[400,134,309]	1	hSpCas9	negative selection	1530198
74603626	74603649	14	+	26627737	HeLa	viability after 12 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.830397319166241	[575]	[149,143,106]	-6	hSpCas9	negative selection	1530199
74611848	74611871	14	-	26627737	HeLa	viability after 12 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.8788988574180404	[303]	[355,86,268]	6	hSpCas9	negative selection	1530200
74586096	74586119	14	+	26627737	HeLa	viability after 15 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.15475664369871522	[606]	[261,329,229]	1	hSpCas9	negative selection	1612513
74603626	74603649	14	+	26627737	HeLa	viability after 15 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.6289222258911813	[575]	[189,153,106]	-5	hSpCas9	negative selection	1612514
74611848	74611871	14	-	26627737	HeLa	viability after 15 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.42783081839577536	[303]	[107,203,189]	3	hSpCas9	negative selection	1612515
74586096	74586119	14	+	26627737	HeLa	viability after 18 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.09982209940823239	[606]	[163,262,229]	0	hSpCas9	negative selection	1694828
74603626	74603649	14	+	26627737	HeLa	viability after 18 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.6176995769706651	[575]	[130,125,106]	-5	hSpCas9	negative selection	1694829
74611848	74611871	14	-	26627737	HeLa	viability after 18 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.45694606758416834	[303]	[78,168,189]	4	hSpCas9	negative selection	1694830
74586096	74586119	14	+	26627737	HCT116	viability after 6 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	-1.379373915285717	[712]	[64,30]	-7	hSpCas9	negative selection	1777143
74603626	74603649	14	+	26627737	HCT116	viability after 6 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.44731641553126744	[380]	[71,86]	2	hSpCas9	negative selection	1777144
74611848	74611871	14	-	26627737	HCT116	viability after 6 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	1.0544639617884026	[696]	[632,3]	6	hSpCas9	negative selection	1777145
74586096	74586119	14	+	26627737	HCT116	viability after 8 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.6370115758862349	[373]	[366,251,342]	6	hSpCas9	negative selection	1859458
74603626	74603649	14	+	26627737	HCT116	viability after 8 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.5689550761136319	[505]	[134,246,180]	-6	hSpCas9	negative selection	1859459
74611848	74611871	14	-	26627737	HCT116	viability after 8 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.6248062791397977	[177]	[195,145,112]	6	hSpCas9	negative selection	1859460
74586096	74586119	14	+	26627737	HCT116	viability after 9 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.6669268246560671	[712]	[437,194]	5	hSpCas9	negative selection	1941773
74603626	74603649	14	+	26627737	HCT116	viability after 9 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.49900939136160394	[380]	[164,126]	3	hSpCas9	negative selection	1941774
74611848	74611871	14	-	26627737	HCT116	viability after 9 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	-0.4071258900561096	[696]	[74,191]	-3	hSpCas9	negative selection	1941775
74586096	74586119	14	+	26627737	HCT116	viability after 12 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.30352005758253714	[373]	[173,294,265]	3	hSpCas9	negative selection	2024088
74603626	74603649	14	+	26627737	HCT116	viability after 12 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.8442441846847016	[505]	[122,83,237]	-7	hSpCas9	negative selection	2024089
74611848	74611871	14	-	26627737	HCT116	viability after 12 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	1.0215677996514803	[177]	[98,160,316]	8	hSpCas9	negative selection	2024090
74586096	74586119	14	+	26627737	HCT116	viability after 15 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.4904373079678555	[373]	[301,278,323]	4	hSpCas9	negative selection	2106403
74603626	74603649	14	+	26627737	HCT116	viability after 15 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-1.4170433684868409	[505]	[88,121,112]	-8	hSpCas9	negative selection	2106404
74611848	74611871	14	-	26627737	HCT116	viability after 15 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.9110024020315144	[177]	[269,196,119]	7	hSpCas9	negative selection	2106405
74586096	74586119	14	+	26627737	HCT116	viability after 18 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.3035692601788737	[373]	[190,188,294]	2	hSpCas9	negative selection	2188718
74603626	74603649	14	+	26627737	HCT116	viability after 18 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.9524369861431369	[505]	[62,85,237]	-7	hSpCas9	negative selection	2188719
74611848	74611871	14	-	26627737	HCT116	viability after 18 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.04956225376483081	[177]	[81,84,100]	0	hSpCas9	negative selection	2188720
74588452	74588475	14	+	25494202	A375	resistance to PLX-4720 (puromycin)	CTCAGGTGATCCGCCCACCTCGG	LTBP2	ENSG00000119681	-1.8266088487663314	[149,166]	[13,3]	-8	dCas9-VP64	positive selection	2465170
74588452	74588475	14	+	25494202	A375	resistance to PLX-4720 (zeocin)	CTCAGGTGATCCGCCCACCTCGG	LTBP2	ENSG00000119681	0.6108739619638027	[154,293]	[174,51]	4	dCas9-VP64	positive selection	2560425
74521966	74521989	14	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGCAGGAGTAGGACCCCACGCGG	LTBP2	ENSG00000119681	-0.7559145464892714	[2,2]	[1,0]	-8	hSpCas9	positive selection	3000459
74528615	74528638	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGTCCATGAGGAAAGCCGAGG	LTBP2	ENSG00000119681	-0.464068180953275	[2,2]	[0,1]	-6	hSpCas9	positive selection	3000460
74528564	74528587	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAAGGGCAGAGGAGCAGCGGGG	LTBP2	ENSG00000119681	0.20935354837240167	[3,3]	[2,3]	4	hSpCas9	positive selection	3000461
74549929	74549952	14	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCTGGAGCTGACTACCCAGGAGG	LTBP2	ENSG00000119681	0.12281007316948045	[4,3]	[3,3]	2	hSpCas9	positive selection	3000462
74521966	74521989	14	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGCAGGAGTAGGACCCCACGCGG	LTBP2	ENSG00000119681	0.23992207736005833	[2,2]	[1,2]	4	hSpCas9	positive selection	3068317
74528615	74528638	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGTCCATGAGGAAAGCCGAGG	LTBP2	ENSG00000119681	-0.13966463882407265	[2,2]	[1,0]	-2	hSpCas9	positive selection	3068318
74528564	74528587	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAAGGGCAGAGGAGCAGCGGGG	LTBP2	ENSG00000119681	-0.18030231234625665	[3,3]	[3,0]	-3	hSpCas9	positive selection	3068319
74549929	74549952	14	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCTGGAGCTGACTACCCAGGAGG	LTBP2	ENSG00000119681	-0.32906783133570533	[4,4]	[3,1]	-5	hSpCas9	positive selection	3068320
74585940	74585963		-	24336571	A375	resistance to PLX after 7 days	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.004112925611597706	[6,9]	[7,8]	0	hSpCas9	positive selection	3125656
74585956	74585979		+	24336571	A375	resistance to PLX after 7 days	GAACGCTCGGCCCAGCGTCGAGG	LTBP2	ENSG00000119681	-0.21590894170642058	[16,13]	[13,12]	-6	hSpCas9	positive selection	3125657
74603626	74603649		+	24336571	A375	resistance to PLX after 7 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.03277556470892762	[5,5]	[4,7]	1	hSpCas9	positive selection	3125659
74585940	74585963		-	24336571	A375	resistance to PLX after 14 days	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.24740633827212033	[7,9]	[3,4]	2	hSpCas9	positive selection	3183449
74585956	74585979		+	24336571	A375	resistance to PLX after 14 days	GAACGCTCGGCCCAGCGTCGAGG	LTBP2	ENSG00000119681	1.4660208254749325	[14,23]	[18,31]	9	hSpCas9	positive selection	3183450
74603626	74603649		+	24336571	A375	resistance to PLX after 14 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.5363666275686605	[4,2]	[2,2]	5	hSpCas9	positive selection	3183452
74585940	74585963		-	24336571	A375	viability after 7 days	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.838667524310563	[16]	[6,9]	-8	hSpCas9	negative selection	3241242
74585956	74585979		+	24336571	A375	viability after 7 days	GAACGCTCGGCCCAGCGTCGAGG	LTBP2	ENSG00000119681	0.33076489506134255	[12]	[16,13]	5	hSpCas9	negative selection	3241243
74603626	74603649		+	24336571	A375	viability after 7 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.34408578632629505	[8]	[5,5]	-5	hSpCas9	negative selection	3241245
74585940	74585963		-	24336571	A375	viability after 14 days	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.8273754773584974	[16]	[7,9]	-7	hSpCas9	negative selection	3299035
74585956	74585979		+	24336571	A375	viability after 14 days	GAACGCTCGGCCCAGCGTCGAGG	LTBP2	ENSG00000119681	0.6760967165923538	[12]	[14,23]	8	hSpCas9	negative selection	3299036
74603626	74603649		+	24336571	A375	viability after 14 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.8336206877450036	[8]	[4,2]	-8	hSpCas9	negative selection	3299038
74603626	74603649	14	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.7495315712471388	[90,90]	[0,0]	3	hSpCas9	positive selection	3377903
74586026	74586049	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.4908666381436253	[214,214]	[0,0]	-3	hSpCas9	positive selection	3377904
74603691	74603714	14	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	2.5024387092823663	[26,26]	[0,0]	8	hSpCas9	positive selection	3377905
74521965	74521988	14	+	26780180	HT29	viability (Avana library 4 designs)	AGCAGGAGTAGGACCCCACGCGG	LTBP2	ENSG00000119681	2.44590987763882	[]	[]	8	hSpCas9	negative selection	3438043
74528615	74528638	14	-	26780180	HT29	viability (Avana library 4 designs)	CCTGTCCATGAGGAAAGCCGAGG	LTBP2	ENSG00000119681	2.17110956163477	[]	[]	7	hSpCas9	negative selection	3438044
74528564	74528587	14	-	26780180	HT29	viability (Avana library 4 designs)	GCAAGGGCAGAGGAGCAGCGGGG	LTBP2	ENSG00000119681	1.25533800846871	[]	[]	5	hSpCas9	negative selection	3438045
74549929	74549952	14	-	26780180	HT29	viability (Avana library 4 designs)	GCTGGAGCTGACTACCCAGGAGG	LTBP2	ENSG00000119681	0.93961213652081	[]	[]	3	hSpCas9	negative selection	3438046
74528615	74528638	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGTCCATGAGGAAAGCCGAGG	LTBP2	ENSG00000119681	3.91059872279739	[]	[]	6	hSpCas9	negative selection	3527053
74549929	74549952	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCTGGAGCTGACTACCCAGGAGG	LTBP2	ENSG00000119681	6.40718471944486	[]	[]	9	hSpCas9	negative selection	3527054
74521965	74521988	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGCAGGAGTAGGACCCCACGCGG	LTBP2	ENSG00000119681	3.45741687839395	[]	[]	5	hSpCas9	negative selection	3527055
74528564	74528587	14	-	26780180	A375	viability (Avana lentiCRISPRv2)	GCAAGGGCAGAGGAGCAGCGGGG	LTBP2	ENSG00000119681	0.365245570695027	[]	[]	0	hSpCas9	negative selection	3527056
74532414	74532437	14	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCAGCACTCACACACACAGCGG	LTBP2	ENSG00000119681	-10.9323933937593	[]	[]	-8	hSpCas9	negative selection	3527057
74528615	74528638	14	-	26780180	A375	viability (Avana lentiGuide)	CCTGTCCATGAGGAAAGCCGAGG	LTBP2	ENSG00000119681	2.37253855981043	[]	[]	2	hSpCas9	negative selection	3635712
74549929	74549952	14	-	26780180	A375	viability (Avana lentiGuide)	GCTGGAGCTGACTACCCAGGAGG	LTBP2	ENSG00000119681	-0.699143917296711	[]	[]	-1	hSpCas9	negative selection	3635713
74521965	74521988	14	+	26780180	A375	viability (Avana lentiGuide)	AGCAGGAGTAGGACCCCACGCGG	LTBP2	ENSG00000119681	1.24585371968374	[]	[]	1	hSpCas9	negative selection	3635714
74528564	74528587	14	-	26780180	A375	viability (Avana lentiGuide)	GCAAGGGCAGAGGAGCAGCGGGG	LTBP2	ENSG00000119681	7.52188326427914	[]	[]	6	hSpCas9	negative selection	3635715
74532414	74532437	14	+	26780180	A375	viability (Avana lentiGuide)	GCCAGCACTCACACACACAGCGG	LTBP2	ENSG00000119681	-2.36264664520011	[]	[]	-4	hSpCas9	negative selection	3635716
74528615	74528638	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGTCCATGAGGAAAGCCGAGG	LTBP2	ENSG00000119681	0.09690043255866304	[4]	[4,4]	2	hSpCas9	positive selection	3744371
74549929	74549952	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCTGGAGCTGACTACCCAGGAGG	LTBP2	ENSG00000119681	0.3153460114948523	[4]	[5,5]	8	hSpCas9	positive selection	3744372
74521965	74521988	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGCAGGAGTAGGACCCCACGCGG	LTBP2	ENSG00000119681	0.2900000998612373	[3]	[4,4]	8	hSpCas9	positive selection	3744373
74528564	74528587	14	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAAGGGCAGAGGAGCAGCGGGG	LTBP2	ENSG00000119681	0.2620031045002116	[4]	[4,5]	7	hSpCas9	positive selection	3744374
74532414	74532437	14	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCAGCACTCACACACACAGCGG	LTBP2	ENSG00000119681	-0.8991310263348431	[3]	[1,0]	-8	hSpCas9	positive selection	3744375
74528615	74528638	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGTCCATGAGGAAAGCCGAGG	LTBP2	ENSG00000119681	0.06320913837284638	[5]	[5,3]	1	hSpCas9	positive selection	3852978
74549929	74549952	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCTGGAGCTGACTACCCAGGAGG	LTBP2	ENSG00000119681	-0.3204044094036742	[5]	[3,2]	-4	hSpCas9	positive selection	3852979
74521965	74521988	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGCAGGAGTAGGACCCCACGCGG	LTBP2	ENSG00000119681	-0.057482645828208806	[4]	[3,3]	-1	hSpCas9	positive selection	3852980
74528564	74528587	14	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAAGGGCAGAGGAGCAGCGGGG	LTBP2	ENSG00000119681	-0.06546520974898656	[5]	[5,2]	-1	hSpCas9	positive selection	3852981
74532414	74532437	14	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCAGCACTCACACACACAGCGG	LTBP2	ENSG00000119681	0.34371978557927363	[4]	[6,3]	8	hSpCas9	positive selection	3852982
74585940	74585963	14	-	26780180	A375	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.708656286846016	[]	[]	2	hSpCas9	negative selection	3958619
74603691	74603714	14	-	26780180	A375	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	1.64351897462569	[]	[]	8	hSpCas9	negative selection	3958620
74603626	74603649	14	+	26780180	A375	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.972696010063498	[]	[]	4	hSpCas9	negative selection	3958621
74586026	74586049	14	-	26780180	A375	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.974904510146852	[]	[]	4	hSpCas9	negative selection	3958622
74585940	74585963	14	-	26780180	HT29	viability (GeCKOv2 library)	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	1.79042712521493	[]	[]	8	hSpCas9	negative selection	4066585
74603691	74603714	14	-	26780180	HT29	viability (GeCKOv2 library)	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	1.71104880012559	[]	[]	8	hSpCas9	negative selection	4066586
74603626	74603649	14	+	26780180	HT29	viability (GeCKOv2 library)	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.887403325703024	[]	[]	4	hSpCas9	negative selection	4066587
74586026	74586049	14	-	26780180	HT29	viability (GeCKOv2 library)	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.718169568241567	[]	[]	2	hSpCas9	negative selection	4066588
74585940	74585963	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.14931786526156554	[3]	[1,2]	-4	hSpCas9	positive selection	4149819
74585956	74585979	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAACGCTCGGCCCAGCGTCGAGG	LTBP2	ENSG00000119681	0.4223878696756803	[3]	[2,4]	8	hSpCas9	positive selection	4149820
74603626	74603649	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.5662790695298475	[3]	[0,1]	-9	hSpCas9	positive selection	4149822
74585940	74585963	14	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.38102106346525016	[2]	[4,0,0,0]	3	hSpCas9	positive selection	4213841
74585956	74585979	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAACGCTCGGCCCAGCGTCGAGG	LTBP2	ENSG00000119681	-0.024255697004907262	[2]	[1,0,1,0]	0	hSpCas9	positive selection	4213842
74603626	74603649	14	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.1784687540350191	[2]	[2,1,0,0]	1	hSpCas9	positive selection	4213844
74585940	74585963	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.670851889148854	[1]	[1,0]	-9	hSpCas9	positive selection	4281252
74603626	74603649	14	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.3921791645482645	[2]	[1,0]	-7	hSpCas9	positive selection	4345511
74586026	74586049	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.3309448976703652	[3]	[4,3]	6	hSpCas9	positive selection	4345512
74603691	74603714	14	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.6668779567807653	[2]	[1,0]	-9	hSpCas9	positive selection	4345513
74521979	74522001	14	-	27760321	OCIAML3	viability	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.3396242778005183	[817,685]	[693,802]	4	hSpCas9	negative selection	4415725
74528516	74528538	14	+	27760321	OCIAML3	viability	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	-0.691565224285146	[543,458]	[244,237]	-6	hSpCas9	negative selection	4415726
74611775	74611797	14	-	27760321	OCIAML3	viability	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.45462684799186204	[1115,980]	[1124,1116]	5	hSpCas9	negative selection	4415727
74611810	74611832	14	+	27760321	OCIAML3	viability	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.18497850245174086	[730,681]	[472,830]	2	hSpCas9	negative selection	4415728
74611833	74611855	14	-	27760321	OCIAML3	viability	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	-0.551016729507847	[340,284]	[145,192]	-5	hSpCas9	negative selection	4415729
74521979	74522001	14	-	27760321	OCIAML2	viability	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	-0.022222219853940572	[817,685]	[474,756]	0	hSpCas9	negative selection	4499188
74528516	74528538	14	+	27760321	OCIAML2	viability	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	-0.14799441263599816	[543,458]	[331,407]	-2	hSpCas9	negative selection	4499189
74611775	74611797	14	-	27760321	OCIAML2	viability	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.12208633898612864	[1115,980]	[821,1051]	1	hSpCas9	negative selection	4499190
74611810	74611832	14	+	27760321	OCIAML2	viability	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	-0.4443070431885421	[730,681]	[345,517]	-5	hSpCas9	negative selection	4499191
74611833	74611855	14	-	27760321	OCIAML2	viability	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.6169652749250367	[340,284]	[318,475]	8	hSpCas9	negative selection	4499192
74521979	74522001	14	-	27760321	MV411	viability	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	-0.03079525210736389	[817,685]	[556,373]	0	hSpCas9	negative selection	4582651
74528516	74528538	14	+	27760321	MV411	viability	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.33941528836778767	[543,458]	[395,448]	2	hSpCas9	negative selection	4582652
74611775	74611797	14	-	27760321	MV411	viability	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.40403559738080363	[1115,980]	[1035,729]	3	hSpCas9	negative selection	4582653
74611810	74611832	14	+	27760321	MV411	viability	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	-0.09849953888289797	[730,681]	[244,721]	0	hSpCas9	negative selection	4582654
74611833	74611855	14	-	27760321	MV411	viability	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.502859411988218	[340,284]	[165,479]	3	hSpCas9	negative selection	4582655
74521979	74522001	14	-	27760321	HL60	viability	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.3107154615787071	[817,685]	[822,690]	4	hSpCas9	negative selection	4666114
74528516	74528538	14	+	27760321	HL60	viability	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	-0.02776061839662533	[543,458]	[412,386]	0	hSpCas9	negative selection	4666115
74611775	74611797	14	-	27760321	HL60	viability	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.576256996613981	[1115,980]	[1471,1064]	7	hSpCas9	negative selection	4666116
74611810	74611832	14	+	27760321	HL60	viability	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.0370840368436568	[730,681]	[605,577]	0	hSpCas9	negative selection	4666117
74611833	74611855	14	-	27760321	HL60	viability	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.7843316131883623	[340,284]	[324,558]	8	hSpCas9	negative selection	4666118
74521979	74522001	14	-	27760321	HT1080	viability	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.18751872662712477	[685,535]	[249,306]	0	hSpCas9	negative selection	4749577
74528516	74528538	14	+	27760321	HT1080	viability	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	-0.5196136848128474	[458,357]	[39,193]	-2	hSpCas9	negative selection	4749578
74611775	74611797	14	-	27760321	HT1080	viability	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	1.4914178794297013	[980,765]	[923,1037]	7	hSpCas9	negative selection	4749579
74611810	74611832	14	+	27760321	HT1080	viability	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	-0.09791077468893661	[681,531]	[192,261]	0	hSpCas9	negative selection	4749580
74611833	74611855	14	-	27760321	HT1080	viability	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.19502106223160587	[284,222]	[196,26]	1	hSpCas9	negative selection	4749581
74521979	74522001	14	-	27760321	HT29	viability after 7 days	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.1674947293177007	[685,535]	[1137,909,641]	2	hSpCas9	negative selection	4833040
74528516	74528538	14	+	27760321	HT29	viability after 7 days	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.025384503306112416	[458,357]	[599,505,506]	0	hSpCas9	negative selection	4833041
74611775	74611797	14	-	27760321	HT29	viability after 7 days	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.02659004391235653	[980,765]	[1431,1041,1001]	0	hSpCas9	negative selection	4833042
74611810	74611832	14	+	27760321	HT29	viability after 7 days	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.09567993122085838	[681,531]	[840,872,788]	1	hSpCas9	negative selection	4833043
74611833	74611855	14	-	27760321	HT29	viability after 7 days	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.1157190134756293	[284,222]	[374,487,205]	1	hSpCas9	negative selection	4833044
74521979	74522001	14	-	27760321	HT29	viability after 25 days	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.10034649446907806	[685,535]	[985,673,548]	1	hSpCas9	negative selection	4916503
74528516	74528538	14	+	27760321	HT29	viability after 25 days	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.2522123219110716	[458,357]	[458,720,485]	2	hSpCas9	negative selection	4916504
74611775	74611797	14	-	27760321	HT29	viability after 25 days	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.06410336792046545	[980,765]	[1056,902,1182]	0	hSpCas9	negative selection	4916505
74611810	74611832	14	+	27760321	HT29	viability after 25 days	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.09062724290458812	[681,531]	[843,583,784]	0	hSpCas9	negative selection	4916506
74611833	74611855	14	-	27760321	HT29	viability after 25 days	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.18443776552995422	[284,222]	[256,327,417]	1	hSpCas9	negative selection	4916507
74521979	74522001	14	-	27760321	HT29	viability after 22 days	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.04543132432135444	[685,535]	[785,817,579]	0	hSpCas9	negative selection	4999966
74528516	74528538	14	+	27760321	HT29	viability after 22 days	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.1395898482389708	[458,357]	[546,477,534]	1	hSpCas9	negative selection	4999967
74611775	74611797	14	-	27760321	HT29	viability after 22 days	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	-0.09772839147405143	[980,765]	[1052,841,932]	-1	hSpCas9	negative selection	4999968
74611810	74611832	14	+	27760321	HT29	viability after 22 days	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.2475256268415691	[681,531]	[708,795,998]	2	hSpCas9	negative selection	4999969
74611833	74611855	14	-	27760321	HT29	viability after 22 days	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.37972674951535246	[284,222]	[329,510,305]	4	hSpCas9	negative selection	4999970
74521979	74522001	14	-	27760321	HT29	viability after 19 days	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.3364860807751243	[685,535]	[1040,626,990]	3	hSpCas9	negative selection	5083429
74528516	74528538	14	+	27760321	HT29	viability after 19 days	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.5735577094159926	[458,357]	[433,823,795]	6	hSpCas9	negative selection	5083430
74611775	74611797	14	-	27760321	HT29	viability after 19 days	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	-0.06143547814617345	[980,765]	[1051,780,1044]	0	hSpCas9	negative selection	5083431
74611810	74611832	14	+	27760321	HT29	viability after 19 days	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.135090676450916	[681,531]	[698,768,809]	1	hSpCas9	negative selection	5083432
74611833	74611855	14	-	27760321	HT29	viability after 19 days	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.5783508928794218	[284,222]	[573,526,222]	6	hSpCas9	negative selection	5083433
74521979	74522001	14	-	27760321	HT29	viability after 16 days	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.42851310755073835	[685,535]	[1065,875,832]	5	hSpCas9	negative selection	5166892
74528516	74528538	14	+	27760321	HT29	viability after 16 days	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.04640992506891925	[458,357]	[524,693,195]	0	hSpCas9	negative selection	5166893
74611775	74611797	14	-	27760321	HT29	viability after 16 days	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.008698333205943598	[980,765]	[1048,741,1170]	0	hSpCas9	negative selection	5166894
74611810	74611832	14	+	27760321	HT29	viability after 16 days	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.15520185179983004	[681,531]	[738,867,656]	1	hSpCas9	negative selection	5166895
74611833	74611855	14	-	27760321	HT29	viability after 16 days	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.7548213287870553	[284,222]	[677,420,359]	8	hSpCas9	negative selection	5166896
74521979	74522001	14	-	27760321	HT29	viability after 13 days	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.19193919652562064	[685,535]	[911,794,726]	2	hSpCas9	negative selection	5250355
74528516	74528538	14	+	27760321	HT29	viability after 13 days	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.20320423203887938	[458,357]	[457,670,509]	2	hSpCas9	negative selection	5250356
74611775	74611797	14	-	27760321	HT29	viability after 13 days	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.0348201750078867	[980,765]	[970,1166,979]	0	hSpCas9	negative selection	5250357
74611810	74611832	14	+	27760321	HT29	viability after 13 days	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	0.07598516165685942	[681,531]	[935,698,599]	0	hSpCas9	negative selection	5250358
74611833	74611855	14	-	27760321	HT29	viability after 13 days	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.2443118907333608	[284,222]	[392,302,350]	3	hSpCas9	negative selection	5250359
74521979	74522001	14	-	27760321	HT29	viability after 10 days	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.4895786426343397	[685,535]	[1104,1249,867]	6	hSpCas9	negative selection	5333818
74528516	74528538	14	+	27760321	HT29	viability after 10 days	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.6139667187275457	[458,357]	[922,725,692]	8	hSpCas9	negative selection	5333819
74611775	74611797	14	-	27760321	HT29	viability after 10 days	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.1648196880342261	[980,765]	[1405,1065,1191]	2	hSpCas9	negative selection	5333820
74611810	74611832	14	+	27760321	HT29	viability after 10 days	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	-0.08844872259690362	[681,531]	[700,953,494]	-1	hSpCas9	negative selection	5333821
74611833	74611855	14	-	27760321	HT29	viability after 10 days	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	0.534385089432989	[284,222]	[505,436,434]	7	hSpCas9	negative selection	5333822
74521979	74522001	14	-	27760321	MOLM13	viability	GGCGCTGCATCAACCGCGTGGG	LTBP2	ENSG00000119681	0.28883788114242726	[817,685]	[767,301]	2	hSpCas9	negative selection	5417281
74528516	74528538	14	+	27760321	MOLM13	viability	TGTCCGTGACGACCCGGAGGGG	LTBP2	ENSG00000119681	0.24750128348314346	[543,458]	[392,284]	1	hSpCas9	negative selection	5417282
74611775	74611797	14	-	27760321	MOLM13	viability	CGAATCGACTGCGGCGCCCTGG	LTBP2	ENSG00000119681	0.5257539485950746	[1115,980]	[1206,545]	3	hSpCas9	negative selection	5417283
74611810	74611832	14	+	27760321	MOLM13	viability	CGGCTCGTATCTCCCTACGGGG	LTBP2	ENSG00000119681	-0.04270516296043503	[730,681]	[364,405]	0	hSpCas9	negative selection	5417284
74611833	74611855	14	-	27760321	MOLM13	viability	GGCGCGGGTCATGCCCAAAGGG	LTBP2	ENSG00000119681	-0.0037980843598169334	[340,284]	[263,99]	0	hSpCas9	negative selection	5417285
74611783	74611806	14	-	27661255	K562	viability	GTGGAGACGCGAATCGACTGCGG	LTBP2	ENSG00000119681	-0.010129710555988547	[1193,1300]	[1102,889]	0	dCas9-KRAB	negative selection	5491324
74612175	74612198	14	-	27661255	K562	viability	GGCACAGGGAGGAGGCGCGAAGG	LTBP2	ENSG00000119681	0.14769109612128217	[475,428]	[452,356]	5	dCas9-KRAB	negative selection	5491325
74585940	74585963	14	-	27260156	BXPC3	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.15898006514176766	[196]	[180,211,147,194]	-4	hSpCas9	negative selection	5553712
74603626	74603649	14	+	27260156	BXPC3	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.08980330053039376	[206]	[144,312,123,231]	-2	hSpCas9	negative selection	5617971
74586026	74586049	14	-	27260156	BXPC3	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.05255430000532946	[740]	[731,786,620,852]	-1	hSpCas9	negative selection	5617972
74603691	74603714	14	-	27260156	BXPC3	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.1956857857742347	[236]	[95,113,98,125]	-9	hSpCas9	negative selection	5617973
74585940	74585963	14	-	27260156	A673	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.15900929493646476	[196]	[217,191,183,256]	-4	hSpCas9	negative selection	5674963
74603626	74603649	14	+	27260156	A673	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.1864410611536771	[206]	[232,117,288,237]	-5	hSpCas9	negative selection	5739222
74586026	74586049	14	-	27260156	A673	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.002476986797488867	[740]	[936,859,807,956]	0	hSpCas9	negative selection	5739223
74603691	74603714	14	-	27260156	A673	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.2897834023010932	[236]	[104,139,109,107]	-9	hSpCas9	negative selection	5739224
74585940	74585963	14	-	27260156	A375	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.24571051448227954	[196]	[103,399,211,98]	-4	hSpCas9	negative selection	5796214
74603626	74603649	14	+	27260156	A375	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.18232940613242987	[206]	[437,409,156,128]	2	hSpCas9	negative selection	5860473
74586026	74586049	14	-	27260156	A375	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.17696809554245507	[740]	[888,1126,880,1026]	2	hSpCas9	negative selection	5860474
74603691	74603714	14	-	27260156	A375	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.630994979805328	[236]	[184,127,175,213]	-7	hSpCas9	negative selection	5860475
74585940	74585963	14	-	27260156	COLO741	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.6190310446725706	[196]	[203,145,145]	-8	hSpCas9	negative selection	5917465
74603626	74603649	14	+	27260156	COLO741	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.07173920710519166	[206]	[179,351,218]	-1	hSpCas9	negative selection	5981724
74586026	74586049	14	-	27260156	COLO741	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.015923055442745748	[740]	[856,1096,910]	0	hSpCas9	negative selection	5981725
74603691	74603714	14	-	27260156	COLO741	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.0376878952015107	[236]	[155,140,145]	-9	hSpCas9	negative selection	5981726
74585940	74585963	14	-	27260156	CAL120	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.16541529119291476	[196]	[158,248,396]	2	hSpCas9	negative selection	6038716
74603626	74603649	14	+	27260156	CAL120	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.40962427103071497	[206]	[137,170,262]	-5	hSpCas9	negative selection	6102975
74586026	74586049	14	-	27260156	CAL120	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.11421620877901861	[740]	[1190,1068,766]	1	hSpCas9	negative selection	6102976
74603691	74603714	14	-	27260156	CAL120	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.8204869848902363	[236]	[225,15,265]	-8	hSpCas9	negative selection	6102977
74585940	74585963	14	-	27260156	CADOES1	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.06005064169262009	[196]	[184,211,182,120]	-1	hSpCas9	negative selection	6159967
74603626	74603649	14	+	27260156	CADOES1	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.24593630263900146	[206]	[200,250,266,192]	4	hSpCas9	negative selection	6224226
74586026	74586049	14	-	27260156	CADOES1	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.12575382544963043	[740]	[623,952,641,790]	2	hSpCas9	negative selection	6224227
74603691	74603714	14	-	27260156	CADOES1	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.2305873895946462	[236]	[76,69,101,127]	-9	hSpCas9	negative selection	6224228
74585940	74585963	14	-	27260156	EWS502	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.11466813984326651	[196]	[182,273,99,210]	-2	hSpCas9	negative selection	6281218
74603626	74603649	14	+	27260156	EWS502	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.05240299754485345	[206]	[170,209,392,137]	0	hSpCas9	negative selection	6345477
74586026	74586049	14	-	27260156	EWS502	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.008880011327284554	[740]	[840,658,841,772]	0	hSpCas9	negative selection	6345478
74603691	74603714	14	-	27260156	EWS502	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.3525794934831836	[236]	[42,101,175,77]	-9	hSpCas9	negative selection	6345479
74585940	74585963	14	-	27260156	EW8	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.23712189076057766	[196]	[132,106,80,228]	-4	hSpCas9	negative selection	6402469
74603626	74603649	14	+	27260156	EW8	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.4380886554487673	[206]	[189,118,107,87]	-7	hSpCas9	negative selection	6466728
74586026	74586049	14	-	27260156	EW8	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.14141455583823948	[740]	[746,817,555,554]	2	hSpCas9	negative selection	6466729
74603691	74603714	14	-	27260156	EW8	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.1602582863264836	[236]	[76,66,45,158]	-9	hSpCas9	negative selection	6466730
74585940	74585963	14	-	27260156	CORL105	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.24582300088811837	[196]	[245,169,508,206]	4	hSpCas9	negative selection	6523720
74603626	74603649	14	+	27260156	CORL105	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.16682197425286338	[206]	[202,285,191,176]	-3	hSpCas9	negative selection	6587979
74586026	74586049	14	-	27260156	CORL105	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.004819812173718407	[740]	[815,818,1077,777]	0	hSpCas9	negative selection	6587980
74603691	74603714	14	-	27260156	CORL105	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.9090368772927071	[236]	[185,105,190,116]	-9	hSpCas9	negative selection	6587981
74585940	74585963	14	-	27260156	HS294T	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.11827554345888625	[196]	[67,89,68,108]	1	hSpCas9	negative selection	6644971
74603626	74603649	14	+	27260156	HS294T	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.2474229575766076	[206]	[94,53,56,59]	-3	hSpCas9	negative selection	6709230
74586026	74586049	14	-	27260156	HS294T	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.10215328703790572	[740]	[306,308,360,240]	1	hSpCas9	negative selection	6709231
74603691	74603714	14	-	27260156	HS294T	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.7499448307519576	[236]	[32,20,19,35]	-9	hSpCas9	negative selection	6709232
74585940	74585963	14	-	27260156	HCC44	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.07500307312578403	[196]	[379,139,204,145]	-1	hSpCas9	negative selection	6766222
74603626	74603649	14	+	27260156	HCC44	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.39640142632617326	[206]	[186,97,219,222]	-6	hSpCas9	negative selection	6830481
74586026	74586049	14	-	27260156	HCC44	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.10794414964411825	[740]	[1027,549,1024,604]	-2	hSpCas9	negative selection	6830482
74603691	74603714	14	-	27260156	HCC44	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.5195562671148504	[236]	[56,152,125,32]	-9	hSpCas9	negative selection	6830483
74585940	74585963	14	-	27260156	G402	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.4532452504648812	[196]	[162,163,193,177]	-5	hSpCas9	negative selection	6887473
74603626	74603649	14	+	27260156	G402	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.9228829861698074	[206]	[205,108,82,142]	-8	hSpCas9	negative selection	6951732
74586026	74586049	14	-	27260156	G402	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.38144798359296683	[740]	[1555,1448,910,875]	5	hSpCas9	negative selection	6951733
74603691	74603714	14	-	27260156	G402	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.7864385986348055	[236]	[192,114,266,98]	-7	hSpCas9	negative selection	6951734
74585940	74585963	14	-	27260156	L33	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.12773936184393775	[196]	[246,97,137,154]	3	hSpCas9	negative selection	7008724
74603626	74603649	14	+	27260156	L33	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.2525814987630003	[206]	[207,144,176,144]	5	hSpCas9	negative selection	7072983
74586026	74586049	14	-	27260156	L33	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.01928742002867956	[740]	[689,304,482,722]	0	hSpCas9	negative selection	7072984
74603691	74603714	14	-	27260156	L33	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.045083210681089	[236]	[128,43,59,126]	-9	hSpCas9	negative selection	7072985
74585940	74585963	14	-	27260156	K562	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.35702437884329163	[196]	[131,289,87,52]	-4	hSpCas9	negative selection	7129975
74603626	74603649	14	+	27260156	K562	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.5525080617922764	[206]	[96,122,142,133]	-6	hSpCas9	negative selection	7194234
74586026	74586049	14	-	27260156	K562	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.0810414628321875	[740]	[532,722,801,707]	1	hSpCas9	negative selection	7194235
74603691	74603714	14	-	27260156	K562	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.9586017788085219	[236]	[76,271,23,69]	-8	hSpCas9	negative selection	7194236
74585940	74585963	14	-	27260156	HT29	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.2549478605830835	[196]	[195,133,199,257]	-5	hSpCas9	negative selection	7251226
74603626	74603649	14	+	27260156	HT29	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.10906721568825284	[206]	[334,286,233,237]	2	hSpCas9	negative selection	7315485
74586026	74586049	14	-	27260156	HT29	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.008007836784703293	[740]	[1067,1059,803,731]	0	hSpCas9	negative selection	7315486
74603691	74603714	14	-	27260156	HT29	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.1204405199952463	[236]	[215,154,65,103]	-9	hSpCas9	negative selection	7315487
74585940	74585963	14	-	27260156	MHHES1	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.46030230671143824	[196]	[75,320,180,86]	-7	hSpCas9	negative selection	7372477
74603626	74603649	14	+	27260156	MHHES1	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.13973214802125877	[206]	[108,267,230,223]	-3	hSpCas9	negative selection	7436736
74586026	74586049	14	-	27260156	MHHES1	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.03385614034791917	[740]	[1202,877,793,621]	0	hSpCas9	negative selection	7436737
74603691	74603714	14	-	27260156	MHHES1	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.7761383763405858	[236]	[150,204,157,118]	-8	hSpCas9	negative selection	7436738
74585940	74585963	14	-	27260156	MEWO	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.04954620183223235	[196]	[237,140,166]	-1	hSpCas9	negative selection	7493728
74603626	74603649	14	+	27260156	MEWO	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.09687728974343601	[206]	[302,179,156]	2	hSpCas9	negative selection	7557987
74586026	74586049	14	-	27260156	MEWO	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.035969397692692584	[740]	[809,572,768]	0	hSpCas9	negative selection	7557988
74603691	74603714	14	-	27260156	MEWO	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.9536724521545812	[236]	[157,83,109]	-9	hSpCas9	negative selection	7557989
74585940	74585963	14	-	27260156	LNCAPCLONEFGC	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.1579807882980686	[196]	[212,143,188,97]	-3	hSpCas9	negative selection	7614979
74603626	74603649	14	+	27260156	LNCAPCLONEFGC	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.4053819460039294	[206]	[121,145,152,146]	-6	hSpCas9	negative selection	7679238
74586026	74586049	14	-	27260156	LNCAPCLONEFGC	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.2783393278010867	[740]	[740,748,1039,764]	4	hSpCas9	negative selection	7679239
74603691	74603714	14	-	27260156	LNCAPCLONEFGC	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.2793032275110874	[236]	[94,60,125,78]	-9	hSpCas9	negative selection	7679240
74585940	74585963	14	-	27260156	PANC0327	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.06507643537389485	[196]	[372,73,154,95]	-1	hSpCas9	negative selection	7736230
74603626	74603649	14	+	27260156	PANC0327	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.3141995171885912	[206]	[342,139,126,324]	5	hSpCas9	negative selection	7800489
74586026	74586049	14	-	27260156	PANC0327	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.5212646953959666	[740]	[821,1151,1024,742]	7	hSpCas9	negative selection	7800490
74603691	74603714	14	-	27260156	PANC0327	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.9865133022967614	[236]	[95,98,78,150]	-8	hSpCas9	negative selection	7800491
74585940	74585963	14	-	27260156	NCIH2009	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.20696897572298512	[196]	[385,430,146]	3	hSpCas9	negative selection	7857481
74603626	74603649	14	+	27260156	NCIH2009	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.05591782877662044	[206]	[320,257,263]	0	hSpCas9	negative selection	7921740
74586026	74586049	14	-	27260156	NCIH2009	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.20100240839198147	[740]	[1585,1103,957]	2	hSpCas9	negative selection	7921741
74603691	74603714	14	-	27260156	NCIH2009	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.983489495961885	[236]	[252,168,96]	-8	hSpCas9	negative selection	7921742
74585940	74585963	14	-	27260156	NCIH1373	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.13850377528459923	[196]	[321,151,148,99]	1	hSpCas9	negative selection	7978732
74603626	74603649	14	+	27260156	NCIH1373	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.9538973652716651	[206]	[213,75,58,39]	-7	hSpCas9	negative selection	8042991
74586026	74586049	14	-	27260156	NCIH1373	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.6334278978889959	[740]	[1607,845,1891,225]	6	hSpCas9	negative selection	8042992
74603691	74603714	14	-	27260156	NCIH1373	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.19720175313023458	[236]	[181,142,468,31]	-2	hSpCas9	negative selection	8042993
74585940	74585963	14	-	27260156	PATU8902	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.18188190729824627	[196]	[181,325,467,215]	1	hSpCas9	negative selection	8099983
74603626	74603649	14	+	27260156	PATU8902	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.30242122930133164	[206]	[421,498,41,561]	3	hSpCas9	negative selection	8164242
74586026	74586049	14	-	27260156	PATU8902	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.0675198772278891	[740]	[1175,606,1024,1125]	0	hSpCas9	negative selection	8164243
74603691	74603714	14	-	27260156	PATU8902	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.8352198637984194	[236]	[202,249,184,88]	-7	hSpCas9	negative selection	8164244
74585940	74585963	14	-	27260156	PANC1	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.24659993219098308	[196]	[134,197,147,104]	-4	hSpCas9	negative selection	8221234
74603626	74603649	14	+	27260156	PANC1	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.1816126187704643	[206]	[164,170,74,206]	-3	hSpCas9	negative selection	8285493
74586026	74586049	14	-	27260156	PANC1	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.037861670280888604	[740]	[531,1022,625,521]	0	hSpCas9	negative selection	8285494
74603691	74603714	14	-	27260156	PANC1	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.9085316662819651	[236]	[211,105,85,36]	-8	hSpCas9	negative selection	8285495
74585940	74585963	14	-	27260156	PANC0813	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.24221742749528752	[196]	[197,182,179,219]	-4	hSpCas9	negative selection	8342485
74603626	74603649	14	+	27260156	PANC0813	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.07152357380575713	[206]	[283,179,415,150]	1	hSpCas9	negative selection	8406744
74586026	74586049	14	-	27260156	PANC0813	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.19720504706214348	[740]	[804,721,722,787]	-3	hSpCas9	negative selection	8406745
74603691	74603714	14	-	27260156	PANC0813	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.6765713949069387	[236]	[257,210,118,118]	-7	hSpCas9	negative selection	8406746
74585940	74585963	14	-	27260156	RDES	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.03835137507034192	[196]	[263,208,203,181]	0	hSpCas9	negative selection	8463736
74603626	74603649	14	+	27260156	RDES	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.02248003835294421	[206]	[254,177,273,258]	0	hSpCas9	negative selection	8527995
74586026	74586049	14	-	27260156	RDES	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.021849242314008643	[740]	[691,792,981,1043]	0	hSpCas9	negative selection	8527996
74603691	74603714	14	-	27260156	RDES	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.7470199912088367	[236]	[119,136,141,273]	-8	hSpCas9	negative selection	8527997
74585940	74585963	14	-	27260156	PC3	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.10951272790583855	[196]	[50,238,357,193]	-2	hSpCas9	negative selection	8584987
74603626	74603649	14	+	27260156	PC3	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.021089909136826623	[206]	[76,212,449,211]	0	hSpCas9	negative selection	8649246
74586026	74586049	14	-	27260156	PC3	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.024189714260652972	[740]	[393,808,920,943]	0	hSpCas9	negative selection	8649247
74603691	74603714	14	-	27260156	PC3	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.554559812667439	[236]	[34,97,111,102]	-9	hSpCas9	negative selection	8649248
74585940	74585963	14	-	27260156	PATU8988T	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.47640965035710425	[196]	[155,114,207,58]	-6	hSpCas9	negative selection	8706238
74603626	74603649	14	+	27260156	PATU8988T	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.33363506798185427	[206]	[77,180,160,221]	-5	hSpCas9	negative selection	8770497
74586026	74586049	14	-	27260156	PATU8988T	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.2597037276081141	[740]	[522,719,504,661]	-4	hSpCas9	negative selection	8770498
74603691	74603714	14	-	27260156	PATU8988T	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.6308636251307318	[236]	[45,111,12,133]	-9	hSpCas9	negative selection	8770499
74585940	74585963	14	-	27260156	T47D	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.14376995860227848	[196]	[216,216,216,177]	-3	hSpCas9	negative selection	8827489
74603626	74603649	14	+	27260156	T47D	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.24634945836670163	[206]	[195,172,244,200]	-5	hSpCas9	negative selection	8891748
74586026	74586049	14	-	27260156	T47D	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.0505714926030808	[740]	[1062,768,841,914]	1	hSpCas9	negative selection	8891749
74603691	74603714	14	-	27260156	T47D	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.0278982549374196	[236]	[115,111,155,159]	-9	hSpCas9	negative selection	8891750
74585940	74585963	14	-	27260156	SU8686	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	0.11287854273622844	[196]	[302,166,229,124]	2	hSpCas9	negative selection	8948740
74603626	74603649	14	+	27260156	SU8686	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.019071235033822242	[206]	[132,180,269,243]	0	hSpCas9	negative selection	9012999
74586026	74586049	14	-	27260156	SU8686	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.1496131687933101	[740]	[591,567,751,772]	-3	hSpCas9	negative selection	9013000
74603691	74603714	14	-	27260156	SU8686	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.6786187376964352	[236]	[179,137,71,199]	-7	hSpCas9	negative selection	9013001
74585940	74585963	14	-	27260156	SKES1	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.05751275241699294	[196]	[214,255,135,161]	-1	hSpCas9	negative selection	9069991
74603626	74603649	14	+	27260156	SKES1	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.07146852864065334	[206]	[164,314,181,138]	-1	hSpCas9	negative selection	9134250
74586026	74586049	14	-	27260156	SKES1	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.18180770705773042	[740]	[865,1004,795,716]	4	hSpCas9	negative selection	9134251
74603691	74603714	14	-	27260156	SKES1	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.8737885017455218	[236]	[71,50,61,70]	-9	hSpCas9	negative selection	9134252
74585940	74585963	14	-	27260156	TOV112D	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.19282208390698163	[196]	[213,118,265,83]	-4	hSpCas9	negative selection	9191242
74603626	74603649	14	+	27260156	TOV112D	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.027908551630026146	[206]	[271,190,198,183]	0	hSpCas9	negative selection	9255501
74586026	74586049	14	-	27260156	TOV112D	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.0701827045957445	[740]	[843,1004,789,543]	1	hSpCas9	negative selection	9255502
74603691	74603714	14	-	27260156	TOV112D	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-1.3715788846068038	[236]	[133,91,73,70]	-9	hSpCas9	negative selection	9255503
74585940	74585963	14	-	27260156	TC71	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.19584490614327632	[196]	[136,193,164,246]	-5	hSpCas9	negative selection	9312493
74603626	74603649	14	+	27260156	TC71	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.07188500663224517	[206]	[261,207,222,239]	1	hSpCas9	negative selection	9376752
74586026	74586049	14	-	27260156	TC71	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	0.031110259552007746	[740]	[630,716,1027,870]	0	hSpCas9	negative selection	9376753
74603691	74603714	14	-	27260156	TC71	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.991310896463016	[236]	[166,129,102,109]	-9	hSpCas9	negative selection	9376754
74585940	74585963	14	-	27260156	TC32	viability	AGCGTTCACCCAACCTGCGCAGG	LTBP2	ENSG00000119681	-0.1726439858174149	[196]	[122,120,235,203]	-3	hSpCas9	negative selection	9433744
74603626	74603649	14	+	27260156	TC32	viability	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.07487006752092684	[206]	[172,270,177,153]	1	hSpCas9	negative selection	9498003
74586026	74586049	14	-	27260156	TC32	viability	TTTCCGTGGAGCCCGCTGCGAGG	LTBP2	ENSG00000119681	-0.12666561296260848	[740]	[725,403,785,703]	-2	hSpCas9	negative selection	9498004
74603691	74603714	14	-	27260156	TC32	viability	CCCCACAGGAGGAACGTCTGCGG	LTBP2	ENSG00000119681	-0.9241170110676349	[236]	[60,90,174,165]	-9	hSpCas9	negative selection	9498005
74586096	74586119	14	+	27869803	HPAFII	viability after 27 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	1.1407640184945549	[297]	[525,194,NaN]	8	hSpCas9	negative selection	9552369
74603626	74603649	14	+	27869803	HPAFII	viability after 27 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-1.4344947887699264	[264]	[104,6,NaN]	-7	hSpCas9	negative selection	9552370
74611848	74611871	14	-	27869803	HPAFII	viability after 27 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.019452025108331217	[158]	[111,61,NaN]	0	hSpCas9	negative selection	9552371
74586096	74586119	14	+	27869803	HPAFII	viability after 15 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.6910107762856177	[297]	[841,314,NaN]	7	hSpCas9	negative selection	9634818
74603626	74603649	14	+	27869803	HPAFII	viability after 15 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.2811071706118676	[264]	[390,136,NaN]	-3	hSpCas9	negative selection	9634819
74611848	74611871	14	-	27869803	HPAFII	viability after 15 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.07566125806859048	[158]	[176,181,NaN]	0	hSpCas9	negative selection	9634820
74586096	74586119	14	+	27869803	ASPC1	viability after 36 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	0.18991311035394665	[911]	[411,269,398]	1	hSpCas9	negative selection	9717267
74603626	74603649	14	+	27869803	ASPC1	viability after 36 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.26809238237267585	[527]	[168,266,220]	2	hSpCas9	negative selection	9717268
74611848	74611871	14	-	27869803	ASPC1	viability after 36 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	-0.740215447423505	[441]	[51,188,42]	-6	hSpCas9	negative selection	9717269
74586096	74586119	14	+	27869803	PATU8988S	viability after 35 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	-0.4525381463488462	[920]	[297,243,NaN]	-5	hSpCas9	negative selection	9799716
74603626	74603649	14	+	27869803	PATU8988S	viability after 35 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-0.11855199201922842	[461]	[123,218,NaN]	-1	hSpCas9	negative selection	9799717
74611848	74611871	14	-	27869803	PATU8988S	viability after 35 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.5627907652520527	[498]	[454,137,NaN]	6	hSpCas9	negative selection	9799718
74586096	74586119	14	+	27869803	PATU8988S	viability after 31 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	-0.12971443341839306	[920]	[259,431,NaN]	-1	hSpCas9	negative selection	9882165
74603626	74603649	14	+	27869803	PATU8988S	viability after 31 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	0.06323733705685777	[461]	[162,229,NaN]	0	hSpCas9	negative selection	9882166
74611848	74611871	14	-	27869803	PATU8988S	viability after 31 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	0.4049385499631621	[498]	[295,221,NaN]	5	hSpCas9	negative selection	9882167
74586096	74586119	14	+	27869803	HPAFII	viability after 35 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	1.538540071992262	[297]	[592,263,NaN]	8	hSpCas9	negative selection	9964614
74603626	74603649	14	+	27869803	HPAFII	viability after 35 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-1.2524842961985057	[264]	[84,23,NaN]	-6	hSpCas9	negative selection	9964615
74611848	74611871	14	-	27869803	HPAFII	viability after 35 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	-0.17511619481688623	[158]	[67,74,NaN]	-1	hSpCas9	negative selection	9964616
74586096	74586119	14	+	27869803	HPAFII	viability after 31 days	CTGGCACGGCGGCTCGCAAACGG	LTBP2	ENSG00000119681	1.1388003603844514	[297]	[429,300,NaN]	8	hSpCas9	negative selection	10047063
74603626	74603649	14	+	27869803	HPAFII	viability after 31 days	GGCACTCACGTTTGATACAGTGG	LTBP2	ENSG00000119681	-1.1220602907339647	[264]	[97,35,NaN]	-6	hSpCas9	negative selection	10047064
74611848	74611871	14	-	27869803	HPAFII	viability after 31 days	CCTGGCTCTCTTCGTGGGCGCGG	LTBP2	ENSG00000119681	-0.6107332869176446	[158]	[56,59,NaN]	-4	hSpCas9	negative selection	10047065
74585842	74585865	14	+	28162770	P31FUJ	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.5573854344983559	[313]	[542]	6	hSpCas9	negative selection	10186972
74611875	74611898	14	+	28162770	P31FUJ	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.4636860866444663	[141]	[120]	-4	hSpCas9	negative selection	10186973
74586088	74586111	14	-	28162770	P31FUJ	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.4744816219147464	[274]	[448]	5	hSpCas9	negative selection	10186974
74586052	74586075	14	+	28162770	P31FUJ	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-4.210082127914295	[62]	[3]	-9	hSpCas9	negative selection	10186975
74586035	74586058	14	+	28162770	P31FUJ	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	0.6206491322326795	[87]	[158]	7	hSpCas9	negative selection	10186976
74586014	74586037	14	+	28162770	P31FUJ	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.23412827913847356	[470]	[650]	2	hSpCas9	negative selection	10186977
74585842	74585865	14	+	28162770	TF1	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	NaN	[NaN]	[340]	1	hSpCas9	negative selection	10356338
74611875	74611898	14	+	28162770	TF1	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	NaN	[NaN]	[101]	1	hSpCas9	negative selection	10356339
74586088	74586111	14	-	28162770	TF1	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	NaN	[NaN]	[335]	1	hSpCas9	negative selection	10356340
74586052	74586075	14	+	28162770	TF1	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	NaN	[NaN]	[29]	1	hSpCas9	negative selection	10356341
74586035	74586058	14	+	28162770	TF1	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	NaN	[NaN]	[53]	1	hSpCas9	negative selection	10356342
74586014	74586037	14	+	28162770	TF1	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	NaN	[NaN]	[379]	1	hSpCas9	negative selection	10356343
74585842	74585865	14	+	28162770	SKM1	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.8369613841429275	[94]	[299]	7	hSpCas9	negative selection	10525704
74611875	74611898	14	+	28162770	SKM1	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.4838329621274322	[52]	[66]	-4	hSpCas9	negative selection	10525705
74586088	74586111	14	-	28162770	SKM1	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.6088607684185208	[101]	[274]	6	hSpCas9	negative selection	10525706
74586052	74586075	14	+	28162770	SKM1	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-2.748001116578229	[18]	[4]	-9	hSpCas9	negative selection	10525707
74586035	74586058	14	+	28162770	SKM1	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	1.448087465345739	[16]	[81]	9	hSpCas9	negative selection	10525708
74586014	74586037	14	+	28162770	SKM1	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	-0.3074285251922472	[97]	[139]	-3	hSpCas9	negative selection	10525709
74585842	74585865	14	+	28162770	SKM1	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.8369613841429275	[94]	[299]	7	hSpCas9	negative selection	10695070
74611875	74611898	14	+	28162770	SKM1	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.4838329621274322	[52]	[66]	-4	hSpCas9	negative selection	10695071
74586088	74586111	14	-	28162770	SKM1	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.6088607684185208	[101]	[274]	6	hSpCas9	negative selection	10695072
74586052	74586075	14	+	28162770	SKM1	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-2.748001116578229	[18]	[4]	-9	hSpCas9	negative selection	10695073
74586035	74586058	14	+	28162770	SKM1	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	1.448087465345739	[16]	[81]	9	hSpCas9	negative selection	10695074
74586014	74586037	14	+	28162770	SKM1	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	-0.3074285251922472	[97]	[139]	-3	hSpCas9	negative selection	10695075
74585842	74585865	14	+	28162770	PL21	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.021575694773135146	[334]	[147]	0	hSpCas9	negative selection	10864436
74611875	74611898	14	+	28162770	PL21	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.8537272574894155	[190]	[45]	-5	hSpCas9	negative selection	10864437
74586088	74586111	14	-	28162770	PL21	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.09994532643671905	[312]	[145]	0	hSpCas9	negative selection	10864438
74586052	74586075	14	+	28162770	PL21	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-1.095316269036851	[53]	[10]	-6	hSpCas9	negative selection	10864439
74586035	74586058	14	+	28162770	PL21	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	-0.2929003967907966	[75]	[26]	-2	hSpCas9	negative selection	10864440
74586014	74586037	14	+	28162770	PL21	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	-0.45436381948491306	[339]	[107]	-3	hSpCas9	negative selection	10864441
74585842	74585865	14	+	28162770	P31FUJ	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.5573854344983559	[313]	[542]	6	hSpCas9	negative selection	11033802
74611875	74611898	14	+	28162770	P31FUJ	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.4636860866444663	[141]	[120]	-4	hSpCas9	negative selection	11033803
74586088	74586111	14	-	28162770	P31FUJ	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.4744816219147464	[274]	[448]	5	hSpCas9	negative selection	11033804
74586052	74586075	14	+	28162770	P31FUJ	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-4.210082127914295	[62]	[3]	-9	hSpCas9	negative selection	11033805
74586035	74586058	14	+	28162770	P31FUJ	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	0.6206491322326795	[87]	[158]	7	hSpCas9	negative selection	11033806
74586014	74586037	14	+	28162770	P31FUJ	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.23412827913847356	[470]	[650]	2	hSpCas9	negative selection	11033807
74585842	74585865	14	+	28162770	OCIAML5	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.7960436483835034	[148]	[466]	7	hSpCas9	negative selection	11203168
74611875	74611898	14	+	28162770	OCIAML5	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.1906520097049677	[97]	[154]	-1	hSpCas9	negative selection	11203169
74586088	74586111	14	-	28162770	OCIAML5	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	-0.29377202060492097	[181]	[267]	-2	hSpCas9	negative selection	11203170
74586052	74586075	14	+	28162770	OCIAML5	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-3.3545669113931806	[33]	[5]	-9	hSpCas9	negative selection	11203171
74586035	74586058	14	+	28162770	OCIAML5	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	1.4791393376113762	[30]	[155]	9	hSpCas9	negative selection	11203172
74586014	74586037	14	+	28162770	OCIAML5	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.33710631517159373	[181]	[414]	3	hSpCas9	negative selection	11203173
74585842	74585865	14	+	28162770	EOL1	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.29879965600287817	[573]	[371]	2	hSpCas9	negative selection	11372534
74611875	74611898	14	+	28162770	EOL1	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.4183399419524739	[311]	[122]	-3	hSpCas9	negative selection	11372535
74586088	74586111	14	-	28162770	EOL1	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.5589876495800148	[620]	[481]	5	hSpCas9	negative selection	11372536
74586052	74586075	14	+	28162770	EOL1	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-2.366129389332388	[136]	[13]	-8	hSpCas9	negative selection	11372537
74586035	74586058	14	+	28162770	EOL1	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	0.5042159726221778	[90]	[67]	4	hSpCas9	negative selection	11372538
74586014	74586037	14	+	28162770	EOL1	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.7546227701282222	[368]	[327]	6	hSpCas9	negative selection	11372539
74585842	74585865	14	+	28162770	MOLM13	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	-0.03771532756329321	[503]	[354]	0	hSpCas9	negative selection	11541900
74611875	74611898	14	+	28162770	MOLM13	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.7565421850654677	[235]	[100]	-4	hSpCas9	negative selection	11541901
74586088	74586111	14	-	28162770	MOLM13	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.6622910590475768	[512]	[586]	5	hSpCas9	negative selection	11541902
74586052	74586075	14	+	28162770	MOLM13	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-1.175966808230146	[124]	[39]	-6	hSpCas9	negative selection	11541903
74586035	74586058	14	+	28162770	MOLM13	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	-1.420689335786998	[136]	[36]	-6	hSpCas9	negative selection	11541904
74586014	74586037	14	+	28162770	MOLM13	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.5888655793690041	[422]	[459]	4	hSpCas9	negative selection	11541905
74585842	74585865	14	+	28162770	HEL	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.11734088527900766	[343]	[238]	0	hSpCas9	negative selection	11711266
74611875	74611898	14	+	28162770	HEL	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.8766353270932226	[214]	[74]	-5	hSpCas9	negative selection	11711267
74586088	74586111	14	-	28162770	HEL	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.673112481043876	[375]	[383]	6	hSpCas9	negative selection	11711268
74586052	74586075	14	+	28162770	HEL	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-0.8949179539424423	[89]	[30]	-5	hSpCas9	negative selection	11711269
74586035	74586058	14	+	28162770	HEL	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	0.7836013678402065	[77]	[85]	6	hSpCas9	negative selection	11711270
74586014	74586037	14	+	28162770	HEL	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.4918721663737293	[281]	[253]	4	hSpCas9	negative selection	11711271
74585842	74585865	14	+	28162770	MV411	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	-0.6997997883436716	[348]	[180]	-5	hSpCas9	negative selection	11880632
74611875	74611898	14	+	28162770	MV411	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	-0.19313504060320602	[189]	[139]	-1	hSpCas9	negative selection	11880633
74586088	74586111	14	-	28162770	MV411	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.2764166177545413	[344]	[351]	2	hSpCas9	negative selection	11880634
74586052	74586075	14	+	28162770	MV411	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-2.899403837546496	[61]	[6]	-9	hSpCas9	negative selection	11880635
74586035	74586058	14	+	28162770	MV411	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	0.7746845536476441	[67]	[97]	7	hSpCas9	negative selection	11880636
74586014	74586037	14	+	28162770	MV411	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.8976915117556505	[287]	[451]	7	hSpCas9	negative selection	11880637
74585842	74585865	14	+	28162770	MONOMAC1	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.6492979682506268	[192]	[346]	6	hSpCas9	negative selection	12049998
74611875	74611898	14	+	28162770	MONOMAC1	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	1.222392421336448	[122]	[328]	9	hSpCas9	negative selection	12049999
74586088	74586111	14	-	28162770	MONOMAC1	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.9144096891170297	[192]	[416]	8	hSpCas9	negative selection	12050000
74586052	74586075	14	+	28162770	MONOMAC1	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-0.944270776679587	[46]	[27]	-6	hSpCas9	negative selection	12050001
74586035	74586058	14	+	28162770	MONOMAC1	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	0.8782512802446834	[27]	[58]	7	hSpCas9	negative selection	12050002
74586014	74586037	14	+	28162770	MONOMAC1	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.7784408338063771	[177]	[349]	7	hSpCas9	negative selection	12050003
74585842	74585865	14	+	28162770	OCIAML2	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	-0.00807886476068509	[83]	[462]	0	hSpCas9	negative selection	12219364
74611875	74611898	14	+	28162770	OCIAML2	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	0.16797063908106835	[21]	[136]	1	hSpCas9	negative selection	12219365
74586088	74586111	14	-	28162770	OCIAML2	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	0.23782934123505062	[68]	[450]	2	hSpCas9	negative selection	12219366
74586052	74586075	14	+	28162770	OCIAML2	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-1.2075954194083671	[19]	[47]	-7	hSpCas9	negative selection	12219367
74586035	74586058	14	+	28162770	OCIAML2	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	-0.8461389603343679	[11]	[36]	-5	hSpCas9	negative selection	12219368
74586014	74586037	14	+	28162770	OCIAML2	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.3918666510079038	[43]	[319]	4	hSpCas9	negative selection	12219369
74585842	74585865	14	+	28162770	OCIAML3	viability	AAGGGGACTTACCCAGCTGGTGG	LTBP2	ENSG00000119681	0.748384557122915	[97]	[496]	6	hSpCas9	negative selection	12388730
74611875	74611898	14	+	28162770	OCIAML3	viability	GCGGCAGGAAGCCTCTCCAGGGG	LTBP2	ENSG00000119681	0.46949530198199474	[49]	[208]	4	hSpCas9	negative selection	12388731
74586088	74586111	14	-	28162770	OCIAML3	viability	GAGCCGCCGTGCCAGAACCGGGG	LTBP2	ENSG00000119681	-0.7009228442406752	[118]	[220]	-5	hSpCas9	negative selection	12388732
74586052	74586075	14	+	28162770	OCIAML3	viability	GAGCGGCAGACACAGAGCTGCGG	LTBP2	ENSG00000119681	-1.2720795454368008	[15]	[19]	-7	hSpCas9	negative selection	12388733
74586035	74586058	14	+	28162770	OCIAML3	viability	GGGCTCCACGGAAACCAGAGCGG	LTBP2	ENSG00000119681	-4.053439258961461	[21]	[3]	-9	hSpCas9	negative selection	12388734
74586014	74586037	14	+	28162770	OCIAML3	viability	CGGGAATGACCTCCTCGCAGCGG	LTBP2	ENSG00000119681	0.9084927002050203	[77]	[441]	7	hSpCas9	negative selection	12388735