Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4054
• Symbol:LTBP3
• Description:latent transforming growth factor beta binding protein 3

DataSource: http://genomecrispr.dkfz.de/#!/results/LTBP3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
65553712	65553735	11	+	26472758	Jiyoye	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.13794685468349144	[374]	[256]	-1	hSpCas9	negative selection	93863
65547938	65547961	11	+	26472758	Jiyoye	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	-0.6802874597444661	[101]	[47]	-5	hSpCas9	negative selection	93864
65557767	65557790	11	-	26472758	Jiyoye	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.3002601775893615	[125]	[116]	2	hSpCas9	negative selection	93865
65553779	65553802	11	+	26472758	Jiyoye	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.05723291044891443	[64]	[50]	0	hSpCas9	negative selection	93866
65553234	65553257	11	-	26472758	Jiyoye	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.5190682615767706	[61]	[66]	4	hSpCas9	negative selection	93867
65552877	65552900	11	+	26472758	Jiyoye	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.19906718617567298	[66]	[57]	1	hSpCas9	negative selection	93868
65552353	65552376	11	+	26472758	Jiyoye	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	2.4071753815058727	[0]	[3]	9	hSpCas9	negative selection	93869
65552125	65552148	11	-	26472758	Jiyoye	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	0.614980266619275	[141]	[163]	4	hSpCas9	negative selection	93870
65551406	65551429	11	+	26472758	Jiyoye	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	-0.405454482592405	[136]	[77]	-3	hSpCas9	negative selection	93871
65547963	65547986	11	+	26472758	Jiyoye	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.5765432477431847	[792]	[400]	-4	hSpCas9	negative selection	93872
65553712	65553735	11	+	26472758	KBM7	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.5192843585882929	[1669,1542]	[650,416]	-4	hSpCas9	negative selection	284981
65547938	65547961	11	+	26472758	KBM7	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.3610544715330751	[368,115]	[113,161]	4	hSpCas9	negative selection	284982
65557767	65557790	11	-	26472758	KBM7	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.0702402287985805	[300,305]	[132,139]	0	hSpCas9	negative selection	284983
65553779	65553802	11	+	26472758	KBM7	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.472040412066636	[395,281]	[135,291]	5	hSpCas9	negative selection	284984
65553234	65553257	11	-	26472758	KBM7	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.7156580776233872	[264,183]	[189,153]	7	hSpCas9	negative selection	284985
65552877	65552900	11	+	26472758	KBM7	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.844233644175143	[497,337]	[457,248]	8	hSpCas9	negative selection	284986
65552353	65552376	11	+	26472758	KBM7	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	1.9714377930797957	[69,48]	[225,2]	9	hSpCas9	negative selection	284987
65552125	65552148	11	-	26472758	KBM7	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.28633333668107874	[637,446]	[226,187]	-3	hSpCas9	negative selection	284988
65551406	65551429	11	+	26472758	KBM7	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	-0.5889349017692598	[664,540]	[150,219]	-5	hSpCas9	negative selection	284989
65547963	65547986	11	+	26472758	KBM7	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.3466176958458629	[2983,2917]	[967,1208]	-3	hSpCas9	negative selection	284990
65553712	65553735	11	+	26472758	Raji	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.5058284421517303	[721]	[117]	-4	hSpCas9	negative selection	476099
65547938	65547961	11	+	26472758	Raji	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.006297410259284986	[132]	[30]	0	hSpCas9	negative selection	476100
65557767	65557790	11	-	26472758	Raji	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.47757896534755667	[221]	[36]	-4	hSpCas9	negative selection	476101
65553779	65553802	11	+	26472758	Raji	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	-0.5226668548760945	[129]	[20]	-4	hSpCas9	negative selection	476102
65553234	65553257	11	-	26472758	Raji	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.5630630191497893	[104]	[35]	5	hSpCas9	negative selection	476103
65552877	65552900	11	+	26472758	Raji	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	1.129751348402054	[127]	[64]	8	hSpCas9	negative selection	476104
65552353	65552376	11	+	26472758	Raji	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-0.996953124441136	[42]	[4]	-6	hSpCas9	negative selection	476105
65552125	65552148	11	-	26472758	Raji	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.840149044732265	[377]	[48]	-6	hSpCas9	negative selection	476106
65551406	65551429	11	+	26472758	Raji	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	-0.6262230467026918	[285]	[42]	-5	hSpCas9	negative selection	476107
65547963	65547986	11	+	26472758	Raji	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-1.0075359031718496	[1723]	[198]	-6	hSpCas9	negative selection	476108
65553712	65553735	11	+	26472758	K562	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.7929952339766702	[1249]	[608]	-5	hSpCas9	negative selection	667217
65547938	65547961	11	+	26472758	K562	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	-0.9914695361542241	[178]	[75]	-5	hSpCas9	negative selection	667218
65557767	65557790	11	-	26472758	K562	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.8457790813051312	[395]	[185]	-5	hSpCas9	negative selection	667219
65553779	65553802	11	+	26472758	K562	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	-1.5720672061432857	[316]	[89]	-7	hSpCas9	negative selection	667220
65553234	65553257	11	-	26472758	K562	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	-0.008796617136900942	[204]	[171]	0	hSpCas9	negative selection	667221
65552877	65552900	11	+	26472758	K562	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.22470049305194173	[220]	[217]	1	hSpCas9	negative selection	667222
65552353	65552376	11	+	26472758	K562	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-0.977973693670001	[55]	[23]	-5	hSpCas9	negative selection	667223
65552125	65552148	11	-	26472758	K562	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.8479263349636387	[628]	[294]	-5	hSpCas9	negative selection	667224
65551406	65551429	11	+	26472758	K562	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	-0.7958451425472803	[435]	[211]	-5	hSpCas9	negative selection	667225
65547963	65547986	11	+	26472758	K562	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.939866670034126	[2826]	[1243]	-5	hSpCas9	negative selection	667226
65552247	65552270	11	-	26627737	DLD1	viability	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.8400230398613574	[700]	[517,301,357]	7	hSpCas9	negative selection	780149
65552860	65552883	11	+	26627737	DLD1	viability	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.820862973103367	[1086]	[258,244,90]	-7	hSpCas9	negative selection	780150
65553163	65553186	11	-	26627737	DLD1	viability	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.08466520767549957	[706]	[149,234,236]	-1	hSpCas9	negative selection	780151
65553868	65553891	11	+	26627737	DLD1	viability	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.3470711683242548	[919]	[417,386,302]	3	hSpCas9	negative selection	780152
65554089	65554112	11	+	26627737	DLD1	viability	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	0.6586126896639745	[405]	[227,172,198]	6	hSpCas9	negative selection	780153
65557700	65557723	11	-	26627737	DLD1	viability	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.0915128994089549	[1132]	[302,515,326]	0	hSpCas9	negative selection	780154
65552247	65552270	11	-	26627737	GBM cells	viability after 5 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.0018886324033711155	[418]	[229,219]	0	hSpCas9	negative selection	862464
65552860	65552883	11	+	26627737	GBM cells	viability after 5 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.17752072257606466	[561]	[260,271]	-3	hSpCas9	negative selection	862465
65553163	65553186	11	-	26627737	GBM cells	viability after 5 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.1550618951342395	[174]	[85,122]	2	hSpCas9	negative selection	862466
65553868	65553891	11	+	26627737	GBM cells	viability after 5 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.04939111409977537	[472]	[319,204]	0	hSpCas9	negative selection	862467
65554089	65554112	11	+	26627737	GBM cells	viability after 5 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	-0.22059321957040345	[238]	[121,97]	-3	hSpCas9	negative selection	862468
65557700	65557723	11	-	26627737	GBM cells	viability after 5 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.019846277154137226	[327]	[189,156]	0	hSpCas9	negative selection	862469
65552247	65552270	11	-	26627737	GBM cells	viability after 13 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.05578148739872679	[418]	[216,251]	0	hSpCas9	negative selection	944779
65552860	65552883	11	+	26627737	GBM cells	viability after 13 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.07798493069750845	[561]	[257,313]	-1	hSpCas9	negative selection	944780
65553163	65553186	11	-	26627737	GBM cells	viability after 13 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.7409032666605584	[174]	[145,168]	8	hSpCas9	negative selection	944781
65553868	65553891	11	+	26627737	GBM cells	viability after 13 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.40439143158713375	[472]	[210,179]	-5	hSpCas9	negative selection	944782
65554089	65554112	11	+	26627737	GBM cells	viability after 13 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	-0.23384021324796134	[238]	[101,116]	-3	hSpCas9	negative selection	944783
65557700	65557723	11	-	26627737	GBM cells	viability after 13 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.27982336926597384	[327]	[150,142]	-3	hSpCas9	negative selection	944784
65552247	65552270	11	-	26627737	GBM cells	viability after 21 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.43808582094397874	[418]	[298,316]	4	hSpCas9	negative selection	1027094
65552860	65552883	11	+	26627737	GBM cells	viability after 21 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.4748989588554482	[561]	[427,420]	5	hSpCas9	negative selection	1027095
65553163	65553186	11	-	26627737	GBM cells	viability after 21 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.5672086441097515	[174]	[143,137]	6	hSpCas9	negative selection	1027096
65553868	65553891	11	+	26627737	GBM cells	viability after 21 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.5534278001775415	[472]	[160,187]	-5	hSpCas9	negative selection	1027097
65554089	65554112	11	+	26627737	GBM cells	viability after 21 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	0.2438612208218214	[238]	[135,169]	2	hSpCas9	negative selection	1027098
65557700	65557723	11	-	26627737	GBM cells	viability after 21 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.33345368100105227	[327]	[154,128]	-3	hSpCas9	negative selection	1027099
65552247	65552270	11	-	26627737	RPE1	viability after 9 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.6182100005885758	[1500]	[251,375]	-4	hSpCas9	negative selection	1109409
65552860	65552883	11	+	26627737	RPE1	viability after 9 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.592311171843988	[1608]	[265,421]	-4	hSpCas9	negative selection	1109410
65553163	65553186	11	-	26627737	RPE1	viability after 9 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	2.833514769371344	[112]	[273,223]	9	hSpCas9	negative selection	1109411
65553868	65553891	11	+	26627737	RPE1	viability after 9 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.5766089304278085	[1887]	[315,499]	-4	hSpCas9	negative selection	1109412
65554089	65554112	11	+	26627737	RPE1	viability after 9 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	-0.995544716361665	[808]	[109,148]	-6	hSpCas9	negative selection	1109413
65557700	65557723	11	-	26627737	RPE1	viability after 9 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	3.201965829149244	[284]	[693,984]	9	hSpCas9	negative selection	1109414
65552247	65552270	11	-	26627737	RPE1	viability after 12 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.33573122151708057	[1500]	[388,245]	-2	hSpCas9	negative selection	1191724
65552860	65552883	11	+	26627737	RPE1	viability after 12 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.17679069746713494	[1608]	[345,420]	-1	hSpCas9	negative selection	1191725
65553163	65553186	11	-	26627737	RPE1	viability after 12 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	3.224663228431139	[112]	[310,254]	9	hSpCas9	negative selection	1191726
65553868	65553891	11	+	26627737	RPE1	viability after 12 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.4925046874422834	[1887]	[412,304]	-3	hSpCas9	negative selection	1191727
65554089	65554112	11	+	26627737	RPE1	viability after 12 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	-0.7852965834221921	[808]	[129,121]	-5	hSpCas9	negative selection	1191728
65557700	65557723	11	-	26627737	RPE1	viability after 12 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	3.0323653077651356	[284]	[437,825]	9	hSpCas9	negative selection	1191729
65552247	65552270	11	-	26627737	RPE1	viability after 15 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.3744089758757466	[1500]	[324,329]	-2	hSpCas9	negative selection	1274039
65552860	65552883	11	+	26627737	RPE1	viability after 15 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.33640643395556524	[1608]	[620,529]	2	hSpCas9	negative selection	1274040
65553163	65553186	11	-	26627737	RPE1	viability after 15 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	2.933577515506507	[112]	[203,282]	9	hSpCas9	negative selection	1274041
65553868	65553891	11	+	26627737	RPE1	viability after 15 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.23247045776311515	[1887]	[561,350]	-1	hSpCas9	negative selection	1274042
65554089	65554112	11	+	26627737	RPE1	viability after 15 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	-0.4886780745975542	[808]	[213,113]	-3	hSpCas9	negative selection	1274043
65557700	65557723	11	-	26627737	RPE1	viability after 15 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	2.8521425649792764	[284]	[461,697]	9	hSpCas9	negative selection	1274044
65552247	65552270	11	-	26627737	RPE1	viability after 18 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.1563130948638859	[1500]	[391,332]	-1	hSpCas9	negative selection	1356354
65552860	65552883	11	+	26627737	RPE1	viability after 18 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.02173418769825486	[1608]	[580,290]	0	hSpCas9	negative selection	1356355
65553163	65553186	11	-	26627737	RPE1	viability after 18 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	3.224739178999727	[112]	[374,188]	9	hSpCas9	negative selection	1356356
65553868	65553891	11	+	26627737	RPE1	viability after 18 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.11934735870215896	[1887]	[726,367]	0	hSpCas9	negative selection	1356357
65554089	65554112	11	+	26627737	RPE1	viability after 18 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	-0.7246908815064563	[808]	[149,112]	-4	hSpCas9	negative selection	1356358
65557700	65557723	11	-	26627737	RPE1	viability after 18 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	3.09862161982409	[284]	[653,663]	9	hSpCas9	negative selection	1356359
65552247	65552270	11	-	26627737	HeLa	viability after 8 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.8133965046719837	[1101]	[230,210,360]	-7	hSpCas9	negative selection	1438669
65552860	65552883	11	+	26627737	HeLa	viability after 8 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.08556771743544567	[710]	[250,222,384]	-1	hSpCas9	negative selection	1438670
65553163	65553186	11	-	26627737	HeLa	viability after 8 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.8516551612316519	[170]	[171,102,135]	7	hSpCas9	negative selection	1438671
65553868	65553891	11	+	26627737	HeLa	viability after 8 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.2680046235157436	[1034]	[512,285,354]	-3	hSpCas9	negative selection	1438672
65554089	65554112	11	+	26627737	HeLa	viability after 8 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.416859713110361	[156]	[190,262,100]	8	hSpCas9	negative selection	1438673
65557700	65557723	11	-	26627737	HeLa	viability after 8 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-1.2114701765364897	[474]	[132,78,66]	-8	hSpCas9	negative selection	1438674
65552247	65552270	11	-	26627737	HeLa	viability after 12 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.45423835502496024	[1101]	[545,260,203]	-4	hSpCas9	negative selection	1520984
65552860	65552883	11	+	26627737	HeLa	viability after 12 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.22965018391705927	[710]	[398,232,414]	2	hSpCas9	negative selection	1520985
65553163	65553186	11	-	26627737	HeLa	viability after 12 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.3694456247242086	[170]	[18,111,25]	-3	hSpCas9	negative selection	1520986
65553868	65553891	11	+	26627737	HeLa	viability after 12 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.16272308852171546	[1034]	[556,300,301]	-1	hSpCas9	negative selection	1520987
65554089	65554112	11	+	26627737	HeLa	viability after 12 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.0295205777410648	[156]	[15,216,151]	7	hSpCas9	negative selection	1520988
65557700	65557723	11	-	26627737	HeLa	viability after 12 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.20988239448527235	[474]	[357,131,204]	1	hSpCas9	negative selection	1520989
65552247	65552270	11	-	26627737	HeLa	viability after 15 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.3383962731138521	[1101]	[305,610,130]	-3	hSpCas9	negative selection	1603299
65552860	65552883	11	+	26627737	HeLa	viability after 15 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.28256484693786244	[710]	[158,328,225]	-2	hSpCas9	negative selection	1603300
65553163	65553186	11	-	26627737	HeLa	viability after 15 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.9946904128845386	[170]	[82,96,244]	7	hSpCas9	negative selection	1603301
65553868	65553891	11	+	26627737	HeLa	viability after 15 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.25587234322248853	[1034]	[389,385,753]	2	hSpCas9	negative selection	1603302
65554089	65554112	11	+	26627737	HeLa	viability after 15 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.481149612373806	[156]	[105,157,279]	8	hSpCas9	negative selection	1603303
65557700	65557723	11	-	26627737	HeLa	viability after 15 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.5135129947666628	[474]	[331,320,165]	4	hSpCas9	negative selection	1603304
65552247	65552270	11	-	26627737	HeLa	viability after 18 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.35026539322282924	[1101]	[201,502,130]	-3	hSpCas9	negative selection	1685614
65552860	65552883	11	+	26627737	HeLa	viability after 18 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.29326438555293766	[710]	[105,268,225]	-3	hSpCas9	negative selection	1685615
65553163	65553186	11	-	26627737	HeLa	viability after 18 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	1.0035116976315817	[170]	[55,81,244]	7	hSpCas9	negative selection	1685616
65553868	65553891	11	+	26627737	HeLa	viability after 18 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.27028877744361846	[1034]	[271,318,753]	2	hSpCas9	negative selection	1685617
65554089	65554112	11	+	26627737	HeLa	viability after 18 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.4845333268933132	[156]	[70,131,279]	8	hSpCas9	negative selection	1685618
65557700	65557723	11	-	26627737	HeLa	viability after 18 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.4632133743062111	[474]	[212,254,165]	4	hSpCas9	negative selection	1685619
65552247	65552270	11	-	26627737	HCT116	viability after 6 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.33692616877528425	[1296]	[105,191]	-2	hSpCas9	negative selection	1767929
65552860	65552883	11	+	26627737	HCT116	viability after 6 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.9515450823361404	[844]	[156,311]	5	hSpCas9	negative selection	1767930
65553163	65553186	11	-	26627737	HCT116	viability after 6 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-2.458813104682222	[564]	[10,18]	-8	hSpCas9	negative selection	1767931
65553868	65553891	11	+	26627737	HCT116	viability after 6 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.7109705090724041	[1499]	[657,235]	4	hSpCas9	negative selection	1767932
65554089	65554112	11	+	26627737	HCT116	viability after 6 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.0056485815951395	[348]	[211,53]	5	hSpCas9	negative selection	1767933
65557700	65557723	11	-	26627737	HCT116	viability after 6 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-1.2776767418230106	[1296]	[154,44]	-6	hSpCas9	negative selection	1767934
65552247	65552270	11	-	26627737	HCT116	viability after 8 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.04593286675826325	[622]	[102,351,535]	0	hSpCas9	negative selection	1850244
65552860	65552883	11	+	26627737	HCT116	viability after 8 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.7629318329446744	[938]	[308,316,288]	-7	hSpCas9	negative selection	1850245
65553163	65553186	11	-	26627737	HCT116	viability after 8 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.5858596233563542	[463]	[150,214,144]	-6	hSpCas9	negative selection	1850246
65553868	65553891	11	+	26627737	HCT116	viability after 8 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.31945603356185304	[625]	[403,303,580]	3	hSpCas9	negative selection	1850247
65554089	65554112	11	+	26627737	HCT116	viability after 8 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.8066496149456321	[84]	[128,203,157]	9	hSpCas9	negative selection	1850248
65557700	65557723	11	-	26627737	HCT116	viability after 8 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.38500256309427106	[861]	[290,525,273]	-4	hSpCas9	negative selection	1850249
65552247	65552270	11	-	26627737	HCT116	viability after 9 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.6201887279572766	[1296]	[471,579]	4	hSpCas9	negative selection	1932559
65552860	65552883	11	+	26627737	HCT116	viability after 9 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	1.2018731765681498	[844]	[780,311]	7	hSpCas9	negative selection	1932560
65553163	65553186	11	-	26627737	HCT116	viability after 9 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.7558450719143649	[564]	[66,106]	-5	hSpCas9	negative selection	1932561
65553868	65553891	11	+	26627737	HCT116	viability after 9 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.27845045528996115	[1499]	[308,346]	-2	hSpCas9	negative selection	1932562
65554089	65554112	11	+	26627737	HCT116	viability after 9 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	0.6587278892427676	[348]	[207,98]	5	hSpCas9	negative selection	1932563
65557700	65557723	11	-	26627737	HCT116	viability after 9 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.4234868231687443	[1296]	[174,323]	-3	hSpCas9	negative selection	1932564
65552247	65552270	11	-	26627737	HCT116	viability after 12 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.18433317790257187	[622]	[342,222,291]	-2	hSpCas9	negative selection	2014874
65552860	65552883	11	+	26627737	HCT116	viability after 12 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.3953975111352195	[938]	[476,309,327]	-4	hSpCas9	negative selection	2014875
65553163	65553186	11	-	26627737	HCT116	viability after 12 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.986406924743557	[463]	[113,121,133]	-8	hSpCas9	negative selection	2014876
65553868	65553891	11	+	26627737	HCT116	viability after 12 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.7698134157878265	[625]	[531,588,564]	6	hSpCas9	negative selection	2014877
65554089	65554112	11	+	26627737	HCT116	viability after 12 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.833310347379643	[84]	[61,196,227]	9	hSpCas9	negative selection	2014878
65557700	65557723	11	-	26627737	HCT116	viability after 12 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.3317846177369601	[861]	[453,419,198]	-4	hSpCas9	negative selection	2014879
65552247	65552270	11	-	26627737	HCT116	viability after 15 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.30814653224168675	[622]	[348,299,225]	-3	hSpCas9	negative selection	2097189
65552860	65552883	11	+	26627737	HCT116	viability after 15 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.9666261600116578	[938]	[517,205,134]	-7	hSpCas9	negative selection	2097190
65553163	65553186	11	-	26627737	HCT116	viability after 15 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.8376875661975195	[463]	[299,126,39]	-7	hSpCas9	negative selection	2097191
65553868	65553891	11	+	26627737	HCT116	viability after 15 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.6696004961341815	[625]	[782,449,508]	6	hSpCas9	negative selection	2097192
65554089	65554112	11	+	26627737	HCT116	viability after 15 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.9618923510242487	[84]	[251,215,110]	9	hSpCas9	negative selection	2097193
65557700	65557723	11	-	26627737	HCT116	viability after 15 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.4364102691241072	[861]	[542,373,203]	-4	hSpCas9	negative selection	2097194
65552247	65552270	11	-	26627737	HCT116	viability after 18 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.7073641810515193	[622]	[181,222,143]	-6	hSpCas9	negative selection	2179504
65552860	65552883	11	+	26627737	HCT116	viability after 18 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.20022677305792524	[938]	[782,187,219]	-2	hSpCas9	negative selection	2179505
65553163	65553186	11	-	26627737	HCT116	viability after 18 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.4154435318817824	[463]	[83,241,173]	-4	hSpCas9	negative selection	2179506
65553868	65553891	11	+	26627737	HCT116	viability after 18 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	1.1797302470317912	[625]	[555,770,725]	8	hSpCas9	negative selection	2179507
65554089	65554112	11	+	26627737	HCT116	viability after 18 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.2248903224630372	[84]	[104,67,117]	8	hSpCas9	negative selection	2179508
65557700	65557723	11	-	26627737	HCT116	viability after 18 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.08660430209376657	[861]	[577,190,422]	0	hSpCas9	negative selection	2179509
65558356	65558379	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	AAGTGAGCAGTTGTTTTCCCTGG	LTBP3	ENSG00000168056	-0.8601142986481368	[448,97]	[29,34]	-5	dCas9-VP64	positive selection	2404209
65558292	65558315	11	-	25494202	A375	resistance to PLX-4720 (puromycin)	CGCGGGAGAGGAGCCCGGCCAGG	LTBP3	ENSG00000168056	-0.4246874750434273	[13,49]	[4,4]	-2	dCas9-VP64	positive selection	2404210
65558399	65558422	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	GGCGAGGGGGGCTGGGACGCTGG	LTBP3	ENSG00000168056	1.9044661988541507	[2,0]	[1,0]	6	dCas9-VP64	positive selection	2404211
65550612	65550635	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	TCAAGAGATCGAGACCACCCTGG	LTBP3	ENSG00000168056	-2.120647878954971	[113,80]	[4,3]	-9	dCas9-VP64	positive selection	2422564
65547085	65547108	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CGGCTGTAATCCCAGCACTTTGG	LTBP3	ENSG00000168056	-1.4185181893877035	[80,53]	[4,4]	-7	dCas9-VP64	positive selection	2423388
65558356	65558379	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	AAGTGAGCAGTTGTTTTCCCTGG	LTBP3	ENSG00000168056	1.4660351261539932	[117,155]	[39,201]	7	dCas9-VP64	positive selection	2499464
65558292	65558315	11	-	25494202	A375	resistance to PLX-4720 (zeocin)	CGCGGGAGAGGAGCCCGGCCAGG	LTBP3	ENSG00000168056	0.20977972413770019	[70,58]	[20,26]	1	dCas9-VP64	positive selection	2499465
65558399	65558422	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	GGCGAGGGGGGCTGGGACGCTGG	LTBP3	ENSG00000168056	0.29332559511565925	[16,8]	[4,4]	2	dCas9-VP64	positive selection	2499466
65550612	65550635	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	TCAAGAGATCGAGACCACCCTGG	LTBP3	ENSG00000168056	0.6961972445690721	[83,130]	[14,94]	5	dCas9-VP64	positive selection	2517819
65547085	65547108	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CGGCTGTAATCCCAGCACTTTGG	LTBP3	ENSG00000168056	-0.5867812044469465	[72,239]	[21,43]	-6	dCas9-VP64	positive selection	2518643
65552906	65552929	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	AGACACAGCGATAGGAGCCAGGG	LTBP3	ENSG00000168056	-0.4438579118104326	[2,2]	[1,1]	-6	hSpCas9	positive selection	3000463
65553713	65553736	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.06452431746397591	[4,4]	[4,3]	-1	hSpCas9	positive selection	3000464
65557615	65557638	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCCCCCGGCCCTCACCCACGCGG	LTBP3	ENSG00000168056	0.2369900851511171	[2,3]	[3,2]	5	hSpCas9	positive selection	3000465
65553182	65553205	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	TTAAGCCTCTTGTAGCCCTGGGG	LTBP3	ENSG00000168056	-0.8640543251754231	[3,4]	[2,0]	-8	hSpCas9	positive selection	3000466
65552906	65552929	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	AGACACAGCGATAGGAGCCAGGG	LTBP3	ENSG00000168056	-0.5893662492130285	[2,2]	[1,0]	-7	hSpCas9	positive selection	3068321
65553713	65553736	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	0.5423368760319665	[4,4]	[5,4]	8	hSpCas9	positive selection	3068322
65557615	65557638	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCCCCCGGCCCTCACCCACGCGG	LTBP3	ENSG00000168056	-0.4163737314858898	[2,2]	[2,0]	-6	hSpCas9	positive selection	3068323
65553182	65553205	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	TTAAGCCTCTTGTAGCCCTGGGG	LTBP3	ENSG00000168056	0.6000218877963569	[3,3]	[4,3]	8	hSpCas9	positive selection	3068324
65552069	65552092		+	24336571	A375	resistance to PLX after 7 days	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	-0.1566382044705565	[14,15]	[13,13]	-5	hSpCas9	positive selection	3125660
65552083	65552106		-	24336571	A375	resistance to PLX after 7 days	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	-0.035420290909230046	[53,51]	[51,50]	-1	hSpCas9	positive selection	3125661
65552368	65552391		-	24336571	A375	resistance to PLX after 7 days	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.043821308681455395	[8,6]	[7,6]	-1	hSpCas9	positive selection	3125662
65552241	65552264		+	24336571	A375	resistance to PLX after 7 days	GACTCACCGGTGCCATCTGTTGG	LTBP3	ENSG00000168056	-0.2379594776218752	[23,21]	[18,18]	-7	hSpCas9	positive selection	3125663
65552069	65552092		+	24336571	A375	resistance to PLX after 14 days	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	-1.0324888363984555	[9,22]	[2,3]	-9	hSpCas9	positive selection	3183453
65552083	65552106		-	24336571	A375	resistance to PLX after 14 days	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	-0.7815822177777689	[51,60]	[18,10]	-8	hSpCas9	positive selection	3183454
65552368	65552391		-	24336571	A375	resistance to PLX after 14 days	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.20054806690941585	[7,6]	[4,2]	2	hSpCas9	positive selection	3183455
65552241	65552264		+	24336571	A375	resistance to PLX after 14 days	GACTCACCGGTGCCATCTGTTGG	LTBP3	ENSG00000168056	-0.2542326201144074	[24,28]	[9,10]	-3	hSpCas9	positive selection	3183456
65552069	65552092		+	24336571	A375	viability after 7 days	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.22079081426374264	[13]	[14,15]	3	hSpCas9	negative selection	3241246
65552083	65552106		-	24336571	A375	viability after 7 days	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.3468545191698911	[43]	[53,51]	5	hSpCas9	negative selection	3241247
65552368	65552391		-	24336571	A375	viability after 7 days	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.21571026124064224	[9]	[8,6]	-3	hSpCas9	negative selection	3241248
65552241	65552264		+	24336571	A375	viability after 7 days	GACTCACCGGTGCCATCTGTTGG	LTBP3	ENSG00000168056	0.8256010830477069	[12]	[23,21]	9	hSpCas9	negative selection	3241249
65552069	65552092		+	24336571	A375	viability after 14 days	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.33063560273233633	[13]	[9,22]	4	hSpCas9	negative selection	3299039
65552083	65552106		-	24336571	A375	viability after 14 days	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.444327465860868	[43]	[51,60]	5	hSpCas9	negative selection	3299040
65552368	65552391		-	24336571	A375	viability after 14 days	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.2585041188821134	[9]	[7,6]	-3	hSpCas9	negative selection	3299041
65552241	65552264		+	24336571	A375	viability after 14 days	GACTCACCGGTGCCATCTGTTGG	LTBP3	ENSG00000168056	1.1032078737842368	[12]	[24,28]	9	hSpCas9	negative selection	3299042
65552083	65552106	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	-1.6130385081375693	[467,467]	[0,0]	-9	hSpCas9	positive selection	3377906
65552368	65552391	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	2.7978945928085377	[21,21]	[0,0]	8	hSpCas9	positive selection	3377907
65552253	65552276	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.29726264023180216	[187,187]	[0,0]	-2	hSpCas9	positive selection	3377908
65552905	65552928	11	+	26780180	HT29	viability (Avana library 4 designs)	AGACACAGCGATAGGAGCCAGGG	LTBP3	ENSG00000168056	1.43001122129692	[]	[]	5	hSpCas9	negative selection	3438047
65553712	65553735	11	+	26780180	HT29	viability (Avana library 4 designs)	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	0.887210957787567	[]	[]	3	hSpCas9	negative selection	3438048
65557614	65557637	11	+	26780180	HT29	viability (Avana library 4 designs)	GCCCCCGGCCCTCACCCACGCGG	LTBP3	ENSG00000168056	1.63378538776497	[]	[]	6	hSpCas9	negative selection	3438049
65553181	65553204	11	+	26780180	HT29	viability (Avana library 4 designs)	TTAAGCCTCTTGTAGCCCTGGGG	LTBP3	ENSG00000168056	1.2699675815778	[]	[]	5	hSpCas9	negative selection	3438050
65553712	65553735	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.232620749984783	[]	[]	0	hSpCas9	negative selection	3527058
65553181	65553204	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	TTAAGCCTCTTGTAGCCCTGGGG	LTBP3	ENSG00000168056	1.22500150051508	[]	[]	1	hSpCas9	negative selection	3527059
65552905	65552928	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	AGACACAGCGATAGGAGCCAGGG	LTBP3	ENSG00000168056	-1.29650599642066	[]	[]	-1	hSpCas9	negative selection	3527060
65557614	65557637	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCCCCCGGCCCTCACCCACGCGG	LTBP3	ENSG00000168056	-1.28806789124443	[]	[]	-1	hSpCas9	negative selection	3527061
65554319	65554342	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	ACACAGGCACTGGTTTCGCGAGG	LTBP3	ENSG00000168056	0.321459995274877	[]	[]	0	hSpCas9	negative selection	3527062
65557629	65557652	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CACGGGCTCCGGCTTCCGCGTGG	LTBP3	ENSG00000168056	5.16800055372269	[]	[]	8	hSpCas9	negative selection	3527063
65553712	65553735	11	+	26780180	A375	viability (Avana lentiGuide)	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	4.54155442662625	[]	[]	4	hSpCas9	negative selection	3635717
65553181	65553204	11	+	26780180	A375	viability (Avana lentiGuide)	TTAAGCCTCTTGTAGCCCTGGGG	LTBP3	ENSG00000168056	2.64838344345853	[]	[]	3	hSpCas9	negative selection	3635718
65552905	65552928	11	+	26780180	A375	viability (Avana lentiGuide)	AGACACAGCGATAGGAGCCAGGG	LTBP3	ENSG00000168056	1.75089382818489	[]	[]	2	hSpCas9	negative selection	3635719
65557614	65557637	11	+	26780180	A375	viability (Avana lentiGuide)	GCCCCCGGCCCTCACCCACGCGG	LTBP3	ENSG00000168056	20.4841508001427	[]	[]	8	hSpCas9	negative selection	3635720
65554319	65554342	11	+	26780180	A375	viability (Avana lentiGuide)	ACACAGGCACTGGTTTCGCGAGG	LTBP3	ENSG00000168056	-1.16569541238048	[]	[]	-2	hSpCas9	negative selection	3635721
65557629	65557652	11	-	26780180	A375	viability (Avana lentiGuide)	CACGGGCTCCGGCTTCCGCGTGG	LTBP3	ENSG00000168056	2.80402994886496	[]	[]	3	hSpCas9	negative selection	3635722
65553712	65553735	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	0.014107782917936601	[5]	[5,5]	0	hSpCas9	positive selection	3744376
65553181	65553204	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TTAAGCCTCTTGTAGCCCTGGGG	LTBP3	ENSG00000168056	-0.25339590321856414	[5]	[6,2]	-4	hSpCas9	positive selection	3744377
65552905	65552928	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	AGACACAGCGATAGGAGCCAGGG	LTBP3	ENSG00000168056	0.13159241050308224	[4]	[5,4]	3	hSpCas9	positive selection	3744378
65557614	65557637	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCCCCCGGCCCTCACCCACGCGG	LTBP3	ENSG00000168056	0.04307178251769786	[4]	[4,3]	1	hSpCas9	positive selection	3744379
65554319	65554342	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ACACAGGCACTGGTTTCGCGAGG	LTBP3	ENSG00000168056	0.07862687657198669	[3]	[3,4]	2	hSpCas9	positive selection	3744380
65557629	65557652	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CACGGGCTCCGGCTTCCGCGTGG	LTBP3	ENSG00000168056	0.33775357953988006	[4]	[6,6]	8	hSpCas9	positive selection	3744381
65553712	65553735	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.04476731110451762	[6]	[5,4]	0	hSpCas9	positive selection	3852983
65553181	65553204	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TTAAGCCTCTTGTAGCCCTGGGG	LTBP3	ENSG00000168056	-0.24497590264347527	[6]	[5,3]	-3	hSpCas9	positive selection	3852984
65552905	65552928	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	AGACACAGCGATAGGAGCCAGGG	LTBP3	ENSG00000168056	-0.3412600769677214	[4]	[3,2]	-4	hSpCas9	positive selection	3852985
65557614	65557637	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCCCCCGGCCCTCACCCACGCGG	LTBP3	ENSG00000168056	-0.48861232188698733	[4]	[2,2]	-6	hSpCas9	positive selection	3852986
65554319	65554342	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ACACAGGCACTGGTTTCGCGAGG	LTBP3	ENSG00000168056	0.3694869222855109	[5]	[5,5]	9	hSpCas9	positive selection	3852987
65557629	65557652	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CACGGGCTCCGGCTTCCGCGTGG	LTBP3	ENSG00000168056	0.10951674482432314	[5]	[4,5]	2	hSpCas9	positive selection	3852988
65552069	65552092	11	+	26780180	A375	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.825535329372672	[]	[]	3	hSpCas9	negative selection	3958623
65552083	65552106	11	-	26780180	A375	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	1.07139830965439	[]	[]	5	hSpCas9	negative selection	3958624
65551132	65551155	11	-	26780180	A375	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	1.37900261773359	[]	[]	7	hSpCas9	negative selection	3958625
65552368	65552391	11	-	26780180	A375	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.456807184324983	[]	[]	1	hSpCas9	negative selection	3958626
65551141	65551164	11	+	26780180	A375	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	0.931055758051964	[]	[]	4	hSpCas9	negative selection	3958627
65552253	65552276	11	-	26780180	A375	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	1.68200403561839	[]	[]	9	hSpCas9	negative selection	3958628
65552069	65552092	11	+	26780180	HT29	viability (GeCKOv2 library)	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.37716652656915	[]	[]	1	hSpCas9	negative selection	4066589
65552083	65552106	11	-	26780180	HT29	viability (GeCKOv2 library)	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	1.09168209450845	[]	[]	5	hSpCas9	negative selection	4066590
65551132	65551155	11	-	26780180	HT29	viability (GeCKOv2 library)	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	1.99837940866868	[]	[]	9	hSpCas9	negative selection	4066591
65552368	65552391	11	-	26780180	HT29	viability (GeCKOv2 library)	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.494541093933831	[]	[]	1	hSpCas9	negative selection	4066592
65551141	65551164	11	+	26780180	HT29	viability (GeCKOv2 library)	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	1.23665975396023	[]	[]	6	hSpCas9	negative selection	4066593
65552253	65552276	11	-	26780180	HT29	viability (GeCKOv2 library)	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	1.17954052503951	[]	[]	6	hSpCas9	negative selection	4066594
65552069	65552092	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	-0.19841101881612946	[4]	[3,1]	-5	hSpCas9	positive selection	4149823
65552083	65552106	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.08576519834521384	[5]	[3,3]	2	hSpCas9	positive selection	4149824
65552368	65552391	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.068098283330564	[2]	[1,1]	1	hSpCas9	positive selection	4149825
65552241	65552264	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	GACTCACCGGTGCCATCTGTTGG	LTBP3	ENSG00000168056	0.3373049702747321	[4]	[3,3]	7	hSpCas9	positive selection	4149826
65552069	65552092	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	1.0041316829492262	[3]	[0,0,3,3]	7	hSpCas9	positive selection	4213845
65552083	65552106	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.6899807094881475	[5]	[3,4,3,3]	4	hSpCas9	positive selection	4213846
65552368	65552391	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.40545849459082955	[3]	[1,1,0,0]	-6	hSpCas9	positive selection	4213847
65552241	65552264	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	GACTCACCGGTGCCATCTGTTGG	LTBP3	ENSG00000168056	0.9580328247403987	[4]	[1,2,2,5]	6	hSpCas9	positive selection	4213848
65551141	65551164	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.5418655549131471	[1]	[0,0]	-8	hSpCas9	positive selection	4281255
65552069	65552092	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.17327454149436	[3]	[3,2]	3	hSpCas9	positive selection	4281256
65551132	65551155	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.34821464960194587	[3]	[2,0]	-6	hSpCas9	positive selection	4281257
65552083	65552106	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.09525390008559959	[3]	[3,2]	2	hSpCas9	positive selection	4345514
65552368	65552391	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.5140991905666282	[1]	[0,0]	-8	hSpCas9	positive selection	4345515
65552253	65552276	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.08745307922347118	[2]	[2,1]	-2	hSpCas9	positive selection	4345516
65551132	65551154	11	-	27760321	OCIAML3	viability	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.011261304199322586	[1648,1331]	[1033,1301]	0	hSpCas9	negative selection	4415730
65552859	65552881	11	+	27760321	OCIAML3	viability	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.259525328878464	[892,743]	[654,903]	3	hSpCas9	negative selection	4415731
65552958	65552980	11	-	27760321	OCIAML3	viability	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	-0.30193427378319265	[752,550]	[374,454]	-3	hSpCas9	negative selection	4415732
65554140	65554162	11	+	27760321	OCIAML3	viability	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.9151696168116028	[840,704]	[1056,1237]	9	hSpCas9	negative selection	4415733
65557741	65557763	11	-	27760321	OCIAML3	viability	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	0.16228134562726765	[478,458]	[279,581]	2	hSpCas9	negative selection	4415734
65551132	65551154	11	-	27760321	OCIAML2	viability	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.05968658087033307	[1648,1331]	[1084,1236]	-1	hSpCas9	negative selection	4499193
65552859	65552881	11	+	27760321	OCIAML2	viability	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	-0.034133902591810594	[892,743]	[526,797]	0	hSpCas9	negative selection	4499194
65552958	65552980	11	-	27760321	OCIAML2	viability	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.2165582056927664	[752,550]	[531,705]	3	hSpCas9	negative selection	4499195
65554140	65554162	11	+	27760321	OCIAML2	viability	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.28552431579793724	[840,704]	[586,985]	4	hSpCas9	negative selection	4499196
65557741	65557763	11	-	27760321	OCIAML2	viability	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	-0.5167027182197217	[478,458]	[240,297]	-5	hSpCas9	negative selection	4499197
65551132	65551154	11	-	27760321	MV411	viability	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.5396925448804726	[1648,1331]	[1194,1762]	4	hSpCas9	negative selection	4582656
65552859	65552881	11	+	27760321	MV411	viability	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.8093151530966614	[892,743]	[878,1037]	6	hSpCas9	negative selection	4582657
65552958	65552980	11	-	27760321	MV411	viability	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	1.081112523886943	[752,550]	[1011,735]	7	hSpCas9	negative selection	4582658
65554140	65554162	11	+	27760321	MV411	viability	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.4955892302074505	[840,704]	[669,785]	3	hSpCas9	negative selection	4582659
65557741	65557763	11	-	27760321	MV411	viability	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	1.2819395024655758	[478,458]	[676,868]	8	hSpCas9	negative selection	4582660
65551132	65551154	11	-	27760321	HL60	viability	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.5752662962008244	[1648,1331]	[753,874]	-6	hSpCas9	negative selection	4666119
65552859	65552881	11	+	27760321	HL60	viability	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	-0.4632092667698435	[892,743]	[547,413]	-5	hSpCas9	negative selection	4666120
65552958	65552980	11	-	27760321	HL60	viability	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.03816597944851685	[752,550]	[631,445]	0	hSpCas9	negative selection	4666121
65554140	65554162	11	+	27760321	HL60	viability	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.6603074287312467	[840,704]	[944,1045]	7	hSpCas9	negative selection	4666122
65557741	65557763	11	-	27760321	HL60	viability	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	-0.19039795852627922	[478,458]	[344,326]	-2	hSpCas9	negative selection	4666123
65551132	65551154	11	-	27760321	HT1080	viability	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.17873308566723844	[1331,1039]	[266,827]	0	hSpCas9	negative selection	4749582
65552859	65552881	11	+	27760321	HT1080	viability	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.04611053031920165	[743,580]	[261,283]	0	hSpCas9	negative selection	4749583
65552958	65552980	11	-	27760321	HT1080	viability	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.5564948990867018	[550,429]	[368,197]	3	hSpCas9	negative selection	4749584
65554140	65554162	11	+	27760321	HT1080	viability	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	-0.010914824669581602	[704,549]	[270,222]	0	hSpCas9	negative selection	4749585
65557741	65557763	11	-	27760321	HT1080	viability	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	-0.23321030615764443	[458,357]	[231,35]	-1	hSpCas9	negative selection	4749586
65551132	65551154	11	-	27760321	HT29	viability after 7 days	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.3166360946090463	[1331,1039]	[1156,1222,1279]	-4	hSpCas9	negative selection	4833045
65552859	65552881	11	+	27760321	HT29	viability after 7 days	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.07461541939287253	[743,580]	[1151,767,808]	1	hSpCas9	negative selection	4833046
65552958	65552980	11	-	27760321	HT29	viability after 7 days	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.20372443236299703	[550,429]	[1014,573,632]	3	hSpCas9	negative selection	4833047
65554140	65554162	11	+	27760321	HT29	viability after 7 days	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.3880636026178569	[704,549]	[945,1176,1027]	6	hSpCas9	negative selection	4833048
65557741	65557763	11	-	27760321	HT29	viability after 7 days	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	-0.394264279633164	[458,357]	[462,303,438]	-5	hSpCas9	negative selection	4833049
65551132	65551154	11	-	27760321	HT29	viability after 25 days	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.11965213535761965	[1331,1039]	[1208,1020,1543]	-1	hSpCas9	negative selection	4916508
65552859	65552881	11	+	27760321	HT29	viability after 25 days	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.3030454335978433	[743,580]	[767,1181,852]	3	hSpCas9	negative selection	4916509
65552958	65552980	11	-	27760321	HT29	viability after 25 days	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	-0.056095489329688	[550,429]	[494,511,620]	0	hSpCas9	negative selection	4916510
65554140	65554162	11	+	27760321	HT29	viability after 25 days	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.3641954697515176	[704,549]	[828,776,1195]	4	hSpCas9	negative selection	4916511
65557741	65557763	11	-	27760321	HT29	viability after 25 days	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	0.0432054008703332	[458,357]	[510,477,447]	0	hSpCas9	negative selection	4916512
65551132	65551154	11	-	27760321	HT29	viability after 22 days	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.01761124151137361	[1331,1039]	[1233,1331,1603]	0	hSpCas9	negative selection	4999971
65552859	65552881	11	+	27760321	HT29	viability after 22 days	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	-0.019885137741667114	[743,580]	[772,817,673]	0	hSpCas9	negative selection	4999972
65552958	65552980	11	-	27760321	HT29	viability after 22 days	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.1750953850166081	[550,429]	[454,475,997]	1	hSpCas9	negative selection	4999973
65554140	65554162	11	+	27760321	HT29	viability after 22 days	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.21066585168202556	[704,549]	[715,825,980]	2	hSpCas9	negative selection	4999974
65557741	65557763	11	-	27760321	HT29	viability after 22 days	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	0.20083084653813987	[458,357]	[468,539,621]	2	hSpCas9	negative selection	4999975
65551132	65551154	11	-	27760321	HT29	viability after 19 days	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.11775981724787377	[1331,1039]	[1499,1087,1815]	1	hSpCas9	negative selection	5083434
65552859	65552881	11	+	27760321	HT29	viability after 19 days	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.10947578745112607	[743,580]	[773,1304,384]	1	hSpCas9	negative selection	5083435
65552958	65552980	11	-	27760321	HT29	viability after 19 days	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.4031186117050856	[550,429]	[853,783,603]	4	hSpCas9	negative selection	5083436
65554140	65554162	11	+	27760321	HT29	viability after 19 days	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.21202424082623927	[704,549]	[857,699,933]	2	hSpCas9	negative selection	5083437
65557741	65557763	11	-	27760321	HT29	viability after 19 days	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	0.004701772032465079	[458,357]	[318,545,522]	0	hSpCas9	negative selection	5083438
65551132	65551154	11	-	27760321	HT29	viability after 16 days	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.3467438389658366	[1331,1039]	[1771,2110,1175]	4	hSpCas9	negative selection	5166897
65552859	65552881	11	+	27760321	HT29	viability after 16 days	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.2888110698538139	[743,580]	[1159,845,735]	3	hSpCas9	negative selection	5166898
65552958	65552980	11	-	27760321	HT29	viability after 16 days	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.3832575152698659	[550,429]	[646,663,830]	4	hSpCas9	negative selection	5166899
65554140	65554162	11	+	27760321	HT29	viability after 16 days	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.5032610991012237	[704,549]	[931,921,1126]	6	hSpCas9	negative selection	5166900
65557741	65557763	11	-	27760321	HT29	viability after 16 days	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	0.4085911667411758	[458,357]	[423,397,985]	4	hSpCas9	negative selection	5166901
65551132	65551154	11	-	27760321	HT29	viability after 13 days	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.048998525661203995	[1331,1039]	[1017,1396,1560]	0	hSpCas9	negative selection	5250360
65552859	65552881	11	+	27760321	HT29	viability after 13 days	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	-0.09403214915466218	[743,580]	[679,840,643]	-1	hSpCas9	negative selection	5250361
65552958	65552980	11	-	27760321	HT29	viability after 13 days	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.20138889070873162	[550,429]	[660,686,616]	2	hSpCas9	negative selection	5250362
65554140	65554162	11	+	27760321	HT29	viability after 13 days	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.13652545231642232	[704,549]	[647,989,764]	1	hSpCas9	negative selection	5250363
65557741	65557763	11	-	27760321	HT29	viability after 13 days	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	-0.08990804316534715	[458,357]	[580,285,466]	-1	hSpCas9	negative selection	5250364
65551132	65551154	11	-	27760321	HT29	viability after 10 days	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.032798335502575604	[1331,1039]	[1473,1347,1515]	0	hSpCas9	negative selection	5333823
65552859	65552881	11	+	27760321	HT29	viability after 10 days	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.18087446959994524	[743,580]	[1045,830,932]	2	hSpCas9	negative selection	5333824
65552958	65552980	11	-	27760321	HT29	viability after 10 days	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	0.033650248344814004	[550,429]	[907,390,575]	0	hSpCas9	negative selection	5333825
65554140	65554162	11	+	27760321	HT29	viability after 10 days	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	0.07546669932536731	[704,549]	[675,943,858]	1	hSpCas9	negative selection	5333826
65557741	65557763	11	-	27760321	HT29	viability after 10 days	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	-0.47287958572480016	[458,357]	[293,452,357]	-5	hSpCas9	negative selection	5333827
65551132	65551154	11	-	27760321	MOLM13	viability	GTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.4847479873955838	[1648,1331]	[889,1408]	3	hSpCas9	negative selection	5417286
65552859	65552881	11	+	27760321	MOLM13	viability	CCAATGCACTGTGTACGGGAGG	LTBP3	ENSG00000168056	0.003202942417821264	[892,743]	[253,636]	0	hSpCas9	negative selection	5417287
65552958	65552980	11	-	27760321	MOLM13	viability	TCAACGAGTGCGCAATGCCGGG	LTBP3	ENSG00000168056	-0.645395822503971	[752,550]	[172,283]	-4	hSpCas9	negative selection	5417288
65554140	65554162	11	+	27760321	MOLM13	viability	ATCACCTGGACGGCGTAGATGG	LTBP3	ENSG00000168056	1.1746442201595386	[840,704]	[662,1250]	8	hSpCas9	negative selection	5417289
65557741	65557763	11	-	27760321	MOLM13	viability	TGCGCCGGTGATCTGCAAGCGG	LTBP3	ENSG00000168056	0.17690827519738433	[478,458]	[210,374]	1	hSpCas9	negative selection	5417290
65558040	65558063	11	+	27661255	K562	viability	GAGCCCCGGGAGAGGGTAGGGGG	LTBP3	ENSG00000168056	-1.6439675702980232	[410,571]	[166,88]	-9	dCas9-KRAB	negative selection	5491326
65558196	65558219	11	+	27661255	K562	viability	GAACTCAGGCAGGAGCGAGGAGG	LTBP3	ENSG00000168056	0.20852469804919954	[662,767]	[723,602]	7	dCas9-KRAB	negative selection	5491327
65558212	65558235	11	+	27661255	K562	viability	GAGGAGGCCGGAGCAAGTTGAGG	LTBP3	ENSG00000168056	0.007089563347610017	[1415,1463]	[1266,1059]	0	dCas9-KRAB	negative selection	5491328
65558215	65558238	11	+	27661255	K562	viability	GAGGCCGGAGCAAGTTGAGGCGG	LTBP3	ENSG00000168056	0.04821161033215304	[1779,2014]	[1749,1404]	1	dCas9-KRAB	negative selection	5491329
65557767	65557790	11	-	27661255	K562	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.007064103984167569	[890,761]	[721,616]	0	dCas9-KRAB	negative selection	5491330
65551141	65551164	11	+	27260156	BXPC3	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.3709908630766541	[109]	[108,65,100,76]	-7	hSpCas9	negative selection	5553715
65552069	65552092	11	+	27260156	BXPC3	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.16491418946721187	[485]	[418,481,666,752]	3	hSpCas9	negative selection	5553716
65551132	65551155	11	-	27260156	BXPC3	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.008815561836077651	[530]	[479,600,590,565]	0	hSpCas9	negative selection	5553717
65552083	65552106	11	-	27260156	BXPC3	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.2998725116143127	[915]	[1039,1013,1304,1403]	6	hSpCas9	negative selection	5617974
65552368	65552391	11	-	27260156	BXPC3	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.26305371885507656	[69]	[38,125,92,96]	6	hSpCas9	negative selection	5617975
65552253	65552276	11	-	27260156	BXPC3	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.18074535865674116	[424]	[388,278,412,505]	-4	hSpCas9	negative selection	5617976
65551141	65551164	11	+	27260156	A673	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	0.07961748244574185	[109]	[182,179,113,81]	2	hSpCas9	negative selection	5674966
65552069	65552092	11	+	27260156	A673	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.16204615119050358	[485]	[784,730,490,615]	4	hSpCas9	negative selection	5674967
65551132	65551155	11	-	27260156	A673	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.08766606173081337	[530]	[683,699,562,767]	2	hSpCas9	negative selection	5674968
65552083	65552106	11	-	27260156	A673	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.27830424330996684	[915]	[1500,1278,1173,1404]	6	hSpCas9	negative selection	5739225
65552368	65552391	11	-	27260156	A673	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.3108381501367541	[69]	[102,102,101,108]	7	hSpCas9	negative selection	5739226
65552253	65552276	11	-	27260156	A673	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	0.09262118663598318	[424]	[710,510,512,455]	2	hSpCas9	negative selection	5739227
65551141	65551164	11	+	27260156	A375	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.055179967136561	[109]	[70,44,114,18]	-8	hSpCas9	negative selection	5796217
65552069	65552092	11	+	27260156	A375	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.2915490977360997	[485]	[607,752,701,717]	4	hSpCas9	negative selection	5796218
65551132	65551155	11	-	27260156	A375	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.11141850546766854	[530]	[547,541,638,561]	-2	hSpCas9	negative selection	5796219
65552083	65552106	11	-	27260156	A375	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.4410120098118645	[915]	[1444,1345,1608,1395]	6	hSpCas9	negative selection	5860476
65552368	65552391	11	-	27260156	A375	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.30302271401164615	[69]	[54,65,33,104]	-4	hSpCas9	negative selection	5860477
65552253	65552276	11	-	27260156	A375	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.7618275940052289	[424]	[243,481,261,216]	-7	hSpCas9	negative selection	5860478
65551141	65551164	11	+	27260156	COLO741	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	0.03657597829969994	[109]	[121,117,186]	0	hSpCas9	negative selection	5917468
65552069	65552092	11	+	27260156	COLO741	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.3138849024376219	[485]	[811,687,813]	6	hSpCas9	negative selection	5917469
65551132	65551155	11	-	27260156	COLO741	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.06766375480102035	[530]	[1017,456,683]	1	hSpCas9	negative selection	5917470
65552083	65552106	11	-	27260156	COLO741	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.18535977031384976	[915]	[1617,1185,1217]	4	hSpCas9	negative selection	5981727
65552368	65552391	11	-	27260156	COLO741	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.2681775364465335	[69]	[67,119,36]	-5	hSpCas9	negative selection	5981728
65552253	65552276	11	-	27260156	COLO741	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.12099311843370611	[424]	[523,559,420]	-3	hSpCas9	negative selection	5981729
65551141	65551164	11	+	27260156	CAL120	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.593584329312283	[109]	[33,35,63]	-9	hSpCas9	negative selection	6038719
65552069	65552092	11	+	27260156	CAL120	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.7035209532489836	[485]	[1120,776,1074]	9	hSpCas9	negative selection	6038720
65551132	65551155	11	-	27260156	CAL120	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.24052412677781457	[530]	[711,616,374]	-4	hSpCas9	negative selection	6038721
65552083	65552106	11	-	27260156	CAL120	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.45605292869341685	[915]	[1689,1439,1578]	6	hSpCas9	negative selection	6102978
65552368	65552391	11	-	27260156	CAL120	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.7424103464839655	[69]	[24,68,57]	-8	hSpCas9	negative selection	6102979
65552253	65552276	11	-	27260156	CAL120	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.4387962895667197	[424]	[357,388,417]	-6	hSpCas9	negative selection	6102980
65551141	65551164	11	+	27260156	CADOES1	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.35321699269224194	[109]	[53,104,67,93]	-6	hSpCas9	negative selection	6159970
65552069	65552092	11	+	27260156	CADOES1	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.20562304528134634	[485]	[599,515,416,552]	3	hSpCas9	negative selection	6159971
65551132	65551155	11	-	27260156	CADOES1	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.14574672351612988	[530]	[540,501,502,642]	2	hSpCas9	negative selection	6159972
65552083	65552106	11	-	27260156	CADOES1	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.41475451288409226	[915]	[960,1133,1188,1263]	7	hSpCas9	negative selection	6224229
65552368	65552391	11	-	27260156	CADOES1	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.002936022901333324	[69]	[63,21,77,96]	0	hSpCas9	negative selection	6224230
65552253	65552276	11	-	27260156	CADOES1	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.417551309721208	[424]	[188,315,358,320]	-6	hSpCas9	negative selection	6224231
65551141	65551164	11	+	27260156	EWS502	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.9785188015795958	[109]	[67,40,52,74]	-8	hSpCas9	negative selection	6281221
65552069	65552092	11	+	27260156	EWS502	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.266256278164615	[485]	[600,555,589,739]	4	hSpCas9	negative selection	6281222
65551132	65551155	11	-	27260156	EWS502	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.331294449901391	[530]	[748,724,526,826]	6	hSpCas9	negative selection	6281223
65552083	65552106	11	-	27260156	EWS502	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.39980602995622905	[915]	[1155,1129,1210,1665]	7	hSpCas9	negative selection	6345480
65552368	65552391	11	-	27260156	EWS502	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.5330354301881832	[69]	[76,144,161,42]	8	hSpCas9	negative selection	6345481
65552253	65552276	11	-	27260156	EWS502	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.10557661150314149	[424]	[226,348,594,537]	-2	hSpCas9	negative selection	6345482
65551141	65551164	11	+	27260156	EW8	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.0334671470075527	[109]	[43,79,21,31]	-9	hSpCas9	negative selection	6402472
65552069	65552092	11	+	27260156	EW8	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	-0.09945532424395928	[485]	[482,338,290,381]	-2	hSpCas9	negative selection	6402473
65551132	65551155	11	-	27260156	EW8	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.08867420302036055	[530]	[539,393,294,421]	-2	hSpCas9	negative selection	6402474
65552083	65552106	11	-	27260156	EW8	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.09966835235661253	[915]	[936,840,649,791]	1	hSpCas9	negative selection	6466731
65552368	65552391	11	-	27260156	EW8	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.24251928277425083	[69]	[135,59,18,68]	4	hSpCas9	negative selection	6466732
65552253	65552276	11	-	27260156	EW8	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.23697278430286553	[424]	[346,457,157,234]	-4	hSpCas9	negative selection	6466733
65551141	65551164	11	+	27260156	CORL105	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.2191621290071097	[109]	[45,30,59,84]	-9	hSpCas9	negative selection	6523723
65552069	65552092	11	+	27260156	CORL105	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.4555132192780348	[485]	[681,664,920,872]	8	hSpCas9	negative selection	6523724
65551132	65551155	11	-	27260156	CORL105	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.05556373272803383	[530]	[609,734,819,443]	1	hSpCas9	negative selection	6523725
65552083	65552106	11	-	27260156	CORL105	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.06971587334459983	[915]	[1048,1001,1385,1104]	1	hSpCas9	negative selection	6587982
65552368	65552391	11	-	27260156	CORL105	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.11746952275098588	[69]	[95,63,124,76]	2	hSpCas9	negative selection	6587983
65552253	65552276	11	-	27260156	CORL105	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.3953783770361037	[424]	[238,367,585,347]	-6	hSpCas9	negative selection	6587984
65551141	65551164	11	+	27260156	HS294T	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.3656413363720912	[109]	[15,20,18,86]	-5	hSpCas9	negative selection	6644974
65552069	65552092	11	+	27260156	HS294T	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.3480112586876123	[485]	[273,131,271,285]	5	hSpCas9	negative selection	6644975
65551132	65551155	11	-	27260156	HS294T	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.12885610645163786	[530]	[192,215,279,208]	1	hSpCas9	negative selection	6644976
65552083	65552106	11	-	27260156	HS294T	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.716710873715437	[915]	[549,486,586,733]	8	hSpCas9	negative selection	6709233
65552368	65552391	11	-	27260156	HS294T	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.17523408144785346	[69]	[15,35,20,22]	-2	hSpCas9	negative selection	6709234
65552253	65552276	11	-	27260156	HS294T	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.26949658579203417	[424]	[108,139,158,139]	-4	hSpCas9	negative selection	6709235
65551141	65551164	11	+	27260156	HCC44	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.35462125342180206	[109]	[82,176,90,25]	-5	hSpCas9	negative selection	6766225
65552069	65552092	11	+	27260156	HCC44	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.2116828644046106	[485]	[587,492,990,548]	3	hSpCas9	negative selection	6766226
65551132	65551155	11	-	27260156	HCC44	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.031265237861942685	[530]	[718,601,548,580]	0	hSpCas9	negative selection	6766227
65552083	65552106	11	-	27260156	HCC44	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.38762771652136563	[915]	[1533,845,1686,1484]	6	hSpCas9	negative selection	6830484
65552368	65552391	11	-	27260156	HCC44	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.07504599690989311	[69]	[80,35,135,63]	-1	hSpCas9	negative selection	6830485
65552253	65552276	11	-	27260156	HCC44	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.31133545930917317	[424]	[342,279,540,418]	-5	hSpCas9	negative selection	6830486
65551141	65551164	11	+	27260156	G402	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.0432309442840664	[109]	[73,88,14,83]	-8	hSpCas9	negative selection	6887476
65552069	65552092	11	+	27260156	G402	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.1541777503941259	[485]	[880,608,536,639]	2	hSpCas9	negative selection	6887477
65551132	65551155	11	-	27260156	G402	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.12410390219847449	[530]	[802,540,447,609]	-1	hSpCas9	negative selection	6887478
65552083	65552106	11	-	27260156	G402	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.6209676905475535	[915]	[2311,1475,1845,1325]	7	hSpCas9	negative selection	6951735
65552368	65552391	11	-	27260156	G402	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.8164487197988646	[69]	[271,53,177,110]	8	hSpCas9	negative selection	6951736
65552253	65552276	11	-	27260156	G402	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.09176372513162484	[424]	[848,450,337,362]	-1	hSpCas9	negative selection	6951737
65551141	65551164	11	+	27260156	L33	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.11953414249458	[109]	[67,14,25,55]	-9	hSpCas9	negative selection	7008727
65552069	65552092	11	+	27260156	L33	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.17273073399659067	[485]	[598,260,357,385]	4	hSpCas9	negative selection	7008728
65551132	65551155	11	-	27260156	L33	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.028729982485922317	[530]	[372,246,332,663]	0	hSpCas9	negative selection	7008729
65552083	65552106	11	-	27260156	L33	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.06114023053682638	[915]	[834,355,680,1037]	1	hSpCas9	negative selection	7072986
65552368	65552391	11	-	27260156	L33	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.4938632907946303	[69]	[68,68,37,96]	8	hSpCas9	negative selection	7072987
65552253	65552276	11	-	27260156	L33	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.3716372931090637	[424]	[283,174,178,318]	-7	hSpCas9	negative selection	7072988
65551141	65551164	11	+	27260156	K562	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	0.054110340685948444	[109]	[84,141,41,132]	0	hSpCas9	negative selection	7129978
65552069	65552092	11	+	27260156	K562	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.0117555167051333	[485]	[678,413,583,116]	0	hSpCas9	negative selection	7129979
65551132	65551155	11	-	27260156	K562	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.3395081783735918	[530]	[292,499,376,323]	-4	hSpCas9	negative selection	7129980
65552083	65552106	11	-	27260156	K562	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.5842086848550437	[915]	[864,1141,1482,1332]	7	hSpCas9	negative selection	7194237
65552368	65552391	11	-	27260156	K562	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.1381418987898435	[69]	[58,145,26,46]	1	hSpCas9	negative selection	7194238
65552253	65552276	11	-	27260156	K562	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.2366777899274982	[424]	[355,498,197,246]	-3	hSpCas9	negative selection	7194239
65551141	65551164	11	+	27260156	HT29	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.439918601406641	[109]	[48,100,35,18]	-9	hSpCas9	negative selection	7251229
65552069	65552092	11	+	27260156	HT29	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.06347120176264391	[485]	[744,601,612,524]	1	hSpCas9	negative selection	7251230
65551132	65551155	11	-	27260156	HT29	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.19109522519046737	[530]	[539,691,545,496]	-4	hSpCas9	negative selection	7251231
65552083	65552106	11	-	27260156	HT29	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.277783796515627	[915]	[1305,1347,1531,1216]	5	hSpCas9	negative selection	7315488
65552368	65552391	11	-	27260156	HT29	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.29463809271838315	[69]	[119,147,123,37]	6	hSpCas9	negative selection	7315489
65552253	65552276	11	-	27260156	HT29	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.1861164814909065	[424]	[487,334,514,465]	-4	hSpCas9	negative selection	7315490
65551141	65551164	11	+	27260156	MHHES1	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.0322574763330374	[109]	[126,19,48,50]	-9	hSpCas9	negative selection	7372480
65552069	65552092	11	+	27260156	MHHES1	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	-0.12088745416874205	[485]	[551,497,464,493]	-2	hSpCas9	negative selection	7372481
65551132	65551155	11	-	27260156	MHHES1	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.03640168203225233	[530]	[838,671,536,362]	0	hSpCas9	negative selection	7372482
65552083	65552106	11	-	27260156	MHHES1	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.1293171117918802	[915]	[1163,1137,929,1233]	2	hSpCas9	negative selection	7436739
65552368	65552391	11	-	27260156	MHHES1	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.644985817874737	[69]	[79,161,214,49]	9	hSpCas9	negative selection	7436740
65552253	65552276	11	-	27260156	MHHES1	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.4353282100649958	[424]	[350,456,456,191]	-7	hSpCas9	negative selection	7436741
65551141	65551164	11	+	27260156	MEWO	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.6663485155314186	[109]	[87,65,44]	-8	hSpCas9	negative selection	7493731
65552069	65552092	11	+	27260156	MEWO	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.22906311205963054	[485]	[679,561,384]	5	hSpCas9	negative selection	7493732
65551132	65551155	11	-	27260156	MEWO	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.09857887283168992	[530]	[536,455,412]	-2	hSpCas9	negative selection	7493733
65552083	65552106	11	-	27260156	MEWO	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.07151527949847802	[915]	[1061,830,839]	1	hSpCas9	negative selection	7557990
65552368	65552391	11	-	27260156	MEWO	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.24066734531538003	[69]	[81,79,70]	5	hSpCas9	negative selection	7557991
65552253	65552276	11	-	27260156	MEWO	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.10442191261135456	[424]	[480,370,278]	-2	hSpCas9	negative selection	7557992
65551141	65551164	11	+	27260156	LNCAPCLONEFGC	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.9886364641352916	[109]	[56,19,58,67]	-8	hSpCas9	negative selection	7614982
65552069	65552092	11	+	27260156	LNCAPCLONEFGC	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.24774893060134057	[485]	[402,510,551,631]	4	hSpCas9	negative selection	7614983
65551132	65551155	11	-	27260156	LNCAPCLONEFGC	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.04716937009441949	[530]	[422,642,419,481]	0	hSpCas9	negative selection	7614984
65552083	65552106	11	-	27260156	LNCAPCLONEFGC	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.42211243090792794	[915]	[1041,948,1424,1088]	6	hSpCas9	negative selection	7679241
65552368	65552391	11	-	27260156	LNCAPCLONEFGC	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.02340418186204518	[69]	[35,71,52,86]	0	hSpCas9	negative selection	7679242
65552253	65552276	11	-	27260156	LNCAPCLONEFGC	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.3360608374876036	[424]	[243,255,350,379]	-5	hSpCas9	negative selection	7679243
65551141	65551164	11	+	27260156	PANC0327	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.8998228445355059	[109]	[83,21,62,46]	-8	hSpCas9	negative selection	7736233
65552069	65552092	11	+	27260156	PANC0327	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.16909020258565646	[485]	[500,258,567,643]	2	hSpCas9	negative selection	7736234
65551132	65551155	11	-	27260156	PANC0327	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.08900619414635134	[530]	[468,502,351,443]	-1	hSpCas9	negative selection	7736235
65552083	65552106	11	-	27260156	PANC0327	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.7215175479458004	[915]	[1662,1020,1289,1459]	9	hSpCas9	negative selection	7800492
65552368	65552391	11	-	27260156	PANC0327	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.30260344201734757	[69]	[109,72,87,38]	4	hSpCas9	negative selection	7800493
65552253	65552276	11	-	27260156	PANC0327	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.3340855667381363	[424]	[241,331,320,293]	-5	hSpCas9	negative selection	7800494
65551141	65551164	11	+	27260156	NCIH2009	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.4295885641252046	[109]	[34,95,34]	-9	hSpCas9	negative selection	7857484
65552069	65552092	11	+	27260156	NCIH2009	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.4622029910073153	[485]	[1458,782,668]	6	hSpCas9	negative selection	7857485
65551132	65551155	11	-	27260156	NCIH2009	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.18847305073550846	[530]	[906,735,905]	2	hSpCas9	negative selection	7857486
65552083	65552106	11	-	27260156	NCIH2009	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.4306487577472725	[915]	[1734,1555,1885]	6	hSpCas9	negative selection	7921743
65552368	65552391	11	-	27260156	NCIH2009	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.0070324119593201395	[69]	[136,60,104]	0	hSpCas9	negative selection	7921744
65552253	65552276	11	-	27260156	NCIH2009	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.26333395928464476	[424]	[524,456,507]	-4	hSpCas9	negative selection	7921745
65551141	65551164	11	+	27260156	NCIH1373	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.9638058354460659	[109]	[3,64,41,35]	-7	hSpCas9	negative selection	7978735
65552069	65552092	11	+	27260156	NCIH1373	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.8114997385984257	[485]	[1134,867,1294,137]	7	hSpCas9	negative selection	7978736
65551132	65551155	11	-	27260156	NCIH1373	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.7936510769752061	[530]	[1155,1131,849,260]	7	hSpCas9	negative selection	7978737
65552083	65552106	11	-	27260156	NCIH1373	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.29572096998288566	[915]	[1261,1086,1167,408]	3	hSpCas9	negative selection	8042994
65552368	65552391	11	-	27260156	NCIH1373	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.5639822980376312	[69]	[76,51,47,9]	-5	hSpCas9	negative selection	8042995
65552253	65552276	11	-	27260156	NCIH1373	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-1.209706802041731	[424]	[339,205,118,46]	-8	hSpCas9	negative selection	8042996
65551141	65551164	11	+	27260156	PATU8902	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.9928946328517818	[109]	[108,106,5,106]	-7	hSpCas9	negative selection	8099986
65552069	65552092	11	+	27260156	PATU8902	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.12153040201189133	[485]	[736,829,564,867]	1	hSpCas9	negative selection	8099987
65551132	65551155	11	-	27260156	PATU8902	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.03735419684490268	[530]	[1039,812,313,1003]	0	hSpCas9	negative selection	8099988
65552083	65552106	11	-	27260156	PATU8902	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.30822474367895814	[915]	[1926,1093,1682,1566]	3	hSpCas9	negative selection	8164245
65552368	65552391	11	-	27260156	PATU8902	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.8127873005063091	[69]	[110,148,118,338]	8	hSpCas9	negative selection	8164246
65552253	65552276	11	-	27260156	PATU8902	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.5294225642224337	[424]	[473,242,226,783]	-5	hSpCas9	negative selection	8164247
65551141	65551164	11	+	27260156	PANC1	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.48683768951869544	[109]	[43,45,67,100]	-6	hSpCas9	negative selection	8221237
65552069	65552092	11	+	27260156	PANC1	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.6678130214234993	[485]	[583,772,634,671]	9	hSpCas9	negative selection	8221238
65551132	65551155	11	-	27260156	PANC1	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.2080915304188467	[530]	[479,861,353,478]	3	hSpCas9	negative selection	8221239
65552083	65552106	11	-	27260156	PANC1	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.38651868511113563	[915]	[978,1044,1172,922]	6	hSpCas9	negative selection	8285496
65552368	65552391	11	-	27260156	PANC1	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.2566987568470469	[69]	[107,73,41,62]	4	hSpCas9	negative selection	8285497
65552253	65552276	11	-	27260156	PANC1	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.06268148081293334	[424]	[197,589,375,290]	-1	hSpCas9	negative selection	8285498
65551141	65551164	11	+	27260156	PANC0813	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.4180825480438526	[109]	[113,164,66,44]	-6	hSpCas9	negative selection	8342488
65552069	65552092	11	+	27260156	PANC0813	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.4793671798498016	[485]	[798,946,937,514]	7	hSpCas9	negative selection	8342489
65551132	65551155	11	-	27260156	PANC0813	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.11366848810114677	[530]	[624,640,382,654]	-2	hSpCas9	negative selection	8342490
65552083	65552106	11	-	27260156	PANC0813	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.31722902965095845	[915]	[1296,1531,1318,1214]	5	hSpCas9	negative selection	8406747
65552368	65552391	11	-	27260156	PANC0813	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.3321381158742307	[69]	[63,255,27,63]	5	hSpCas9	negative selection	8406748
65552253	65552276	11	-	27260156	PANC0813	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.43276893071046596	[424]	[261,467,407,332]	-6	hSpCas9	negative selection	8406749
65551141	65551164	11	+	27260156	RDES	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.6099467955931903	[109]	[63,57,63,160]	-8	hSpCas9	negative selection	8463739
65552069	65552092	11	+	27260156	RDES	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.1037326361406237	[485]	[460,566,587,837]	1	hSpCas9	negative selection	8463740
65551132	65551155	11	-	27260156	RDES	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.09086304817659245	[530]	[443,586,628,657]	-1	hSpCas9	negative selection	8463741
65552083	65552106	11	-	27260156	RDES	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.434390091057295	[915]	[1160,1333,1722,1524]	7	hSpCas9	negative selection	8527998
65552368	65552391	11	-	27260156	RDES	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.10000617415351787	[69]	[152,57,43,69]	1	hSpCas9	negative selection	8527999
65552253	65552276	11	-	27260156	RDES	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.348815488650997	[424]	[491,265,338,413]	-5	hSpCas9	negative selection	8528000
65551141	65551164	11	+	27260156	PC3	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.6472255019892295	[109]	[49,33,22,161]	-9	hSpCas9	negative selection	8584990
65552069	65552092	11	+	27260156	PC3	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.2780171593971537	[485]	[332,476,1082,721]	6	hSpCas9	negative selection	8584991
65551132	65551155	11	-	27260156	PC3	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.24602376988962454	[530]	[294,529,653,399]	-5	hSpCas9	negative selection	8584992
65552083	65552106	11	-	27260156	PC3	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.26680517105612844	[915]	[761,1019,1999,993]	6	hSpCas9	negative selection	8649249
65552368	65552391	11	-	27260156	PC3	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.13430067582767347	[69]	[18,74,214,17]	-3	hSpCas9	negative selection	8649250
65552253	65552276	11	-	27260156	PC3	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.2090200057709565	[424]	[187,393,547,456]	-5	hSpCas9	negative selection	8649251
65551141	65551164	11	+	27260156	PATU8988T	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.0400006831401187	[109]	[30,106,25,47]	-9	hSpCas9	negative selection	8706241
65552069	65552092	11	+	27260156	PATU8988T	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.18669362259150302	[485]	[484,422,637,583]	3	hSpCas9	negative selection	8706242
65551132	65551155	11	-	27260156	PATU8988T	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.2953288711664204	[530]	[926,482,565,520]	5	hSpCas9	negative selection	8706243
65552083	65552106	11	-	27260156	PATU8988T	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.2829114650144363	[915]	[1015,1350,965,994]	5	hSpCas9	negative selection	8770500
65552368	65552391	11	-	27260156	PATU8988T	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	-0.4907405313745743	[69]	[26,41,50,73]	-7	hSpCas9	negative selection	8770501
65552253	65552276	11	-	27260156	PATU8988T	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.418769825502894	[424]	[302,341,342,237]	-6	hSpCas9	negative selection	8770502
65551141	65551164	11	+	27260156	T47D	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.7715644530139558	[109]	[103,64,67,63]	-9	hSpCas9	negative selection	8827492
65552069	65552092	11	+	27260156	T47D	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.1337604360716458	[485]	[627,562,549,753]	3	hSpCas9	negative selection	8827493
65551132	65551155	11	-	27260156	T47D	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.31663931670558076	[530]	[591,493,460,438]	-6	hSpCas9	negative selection	8827494
65552083	65552106	11	-	27260156	T47D	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.17247519730805527	[915]	[1166,1276,1080,1282]	3	hSpCas9	negative selection	8891751
65552368	65552391	11	-	27260156	T47D	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.2831550657541859	[69]	[74,95,98,127]	6	hSpCas9	negative selection	8891752
65552253	65552276	11	-	27260156	T47D	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.6842780156923399	[424]	[330,345,288,261]	-8	hSpCas9	negative selection	8891753
65551141	65551164	11	+	27260156	SU8686	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.08164766190083617	[109]	[130,63,119,97]	-1	hSpCas9	negative selection	8948743
65552069	65552092	11	+	27260156	SU8686	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.1539456630779013	[485]	[508,363,658,656]	2	hSpCas9	negative selection	8948744
65551132	65551155	11	-	27260156	SU8686	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.07024047182857823	[530]	[461,546,576,647]	1	hSpCas9	negative selection	8948745
65552083	65552106	11	-	27260156	SU8686	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.3033806432721865	[915]	[1126,913,1312,1157]	5	hSpCas9	negative selection	9013002
65552368	65552391	11	-	27260156	SU8686	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.03675742295065865	[69]	[67,64,91,58]	0	hSpCas9	negative selection	9013003
65552253	65552276	11	-	27260156	SU8686	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.34472621430128025	[424]	[275,294,353,426]	-5	hSpCas9	negative selection	9013004
65551141	65551164	11	+	27260156	SKES1	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-1.0979741297839705	[109]	[22,45,62,65]	-9	hSpCas9	negative selection	9069994
65552069	65552092	11	+	27260156	SKES1	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.24793419804364447	[485]	[753,686,391,511]	5	hSpCas9	negative selection	9069995
65551132	65551155	11	-	27260156	SKES1	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.16632417931331966	[530]	[743,712,570,401]	3	hSpCas9	negative selection	9069996
65552083	65552106	11	-	27260156	SKES1	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.1667812055506258	[915]	[1181,1030,1030,886]	3	hSpCas9	negative selection	9134253
65552368	65552391	11	-	27260156	SKES1	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.4708007765747544	[69]	[58,87,132,98]	8	hSpCas9	negative selection	9134254
65552253	65552276	11	-	27260156	SKES1	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	0.09734835338129749	[424]	[412,510,475,414]	2	hSpCas9	negative selection	9134255
65551141	65551164	11	+	27260156	TOV112D	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	0.0005483988465071477	[109]	[74,247,124,25]	0	hSpCas9	negative selection	9191245
65552069	65552092	11	+	27260156	TOV112D	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.3266188057474539	[485]	[736,945,496,360]	6	hSpCas9	negative selection	9191246
65551132	65551155	11	-	27260156	TOV112D	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.004609024836862957	[530]	[617,719,197,646]	0	hSpCas9	negative selection	9191247
65552083	65552106	11	-	27260156	TOV112D	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.2578253941972971	[915]	[1388,1283,883,904]	5	hSpCas9	negative selection	9255504
65552368	65552391	11	-	27260156	TOV112D	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.07369073138366833	[69]	[41,41,71,126]	1	hSpCas9	negative selection	9255505
65552253	65552276	11	-	27260156	TOV112D	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.2025745152432105	[424]	[260,377,433,397]	-4	hSpCas9	negative selection	9255506
65551141	65551164	11	+	27260156	TC71	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.22584844213723088	[109]	[116,90,65,131]	-6	hSpCas9	negative selection	9312496
65552069	65552092	11	+	27260156	TC71	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	0.23868849388337848	[485]	[702,575,498,686]	6	hSpCas9	negative selection	9312497
65551132	65551155	11	-	27260156	TC71	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	-0.0345927444999552	[530]	[582,456,573,610]	-1	hSpCas9	negative selection	9312498
65552083	65552106	11	-	27260156	TC71	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.3818042640123117	[915]	[1331,1275,1218,1291]	8	hSpCas9	negative selection	9376755
65552368	65552391	11	-	27260156	TC71	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.3494998154313351	[69]	[132,106,58,82]	8	hSpCas9	negative selection	9376756
65552253	65552276	11	-	27260156	TC71	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	0.21771065791903949	[424]	[447,471,461,754]	5	hSpCas9	negative selection	9376757
65551141	65551164	11	+	27260156	TC32	viability	GAGCGATCTCTACGGCGCTGCGG	LTBP3	ENSG00000168056	-0.41059958539394525	[109]	[94,7,117,119]	-6	hSpCas9	negative selection	9433747
65552069	65552092	11	+	27260156	TC32	viability	AAAGTCACTCTCGCCCTGAATGG	LTBP3	ENSG00000168056	-0.007973025424267845	[485]	[457,405,524,426]	0	hSpCas9	negative selection	9433748
65551132	65551155	11	-	27260156	TC32	viability	CGTAGAGATCGCTCCCACTCAGG	LTBP3	ENSG00000168056	0.06512183244878172	[530]	[466,343,798,573]	1	hSpCas9	negative selection	9433749
65552083	65552106	11	-	27260156	TC32	viability	CCACCAGACGCTCACCATTCAGG	LTBP3	ENSG00000168056	0.3088271565570134	[915]	[941,889,1336,1165]	5	hSpCas9	negative selection	9498006
65552368	65552391	11	-	27260156	TC32	viability	GAAGAGCCTGTGTTTCCGCCTGG	LTBP3	ENSG00000168056	0.4996790908184354	[69]	[49,89,133,106]	8	hSpCas9	negative selection	9498007
65552253	65552276	11	-	27260156	TC32	viability	TGTCAGCGCTGCCCAACAGATGG	LTBP3	ENSG00000168056	-0.246451629696224	[424]	[337,248,358,421]	-4	hSpCas9	negative selection	9498008
65552247	65552270	11	-	27869803	HPAFII	viability after 27 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.17024706753158148	[580]	[163,360,NaN]	-1	hSpCas9	negative selection	9543149
65552860	65552883	11	+	27869803	HPAFII	viability after 27 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.2169778269081819	[491]	[251,197,NaN]	-2	hSpCas9	negative selection	9543150
65553163	65553186	11	-	27869803	HPAFII	viability after 27 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.4915621220899588	[190]	[276,27,NaN]	4	hSpCas9	negative selection	9543151
65553868	65553891	11	+	27869803	HPAFII	viability after 27 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	1.1890028372561197	[501]	[646,563,NaN]	8	hSpCas9	negative selection	9543152
65554089	65554112	11	+	27869803	HPAFII	viability after 27 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	0.8350062735262127	[195]	[191,176,NaN]	6	hSpCas9	negative selection	9543153
65557700	65557723	11	-	27869803	HPAFII	viability after 27 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.785930794129687	[452]	[372,441,NaN]	6	hSpCas9	negative selection	9543154
65552247	65552270	11	-	27869803	HPAFII	viability after 15 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.6439788277802494	[580]	[332,440,NaN]	-6	hSpCas9	negative selection	9625598
65552860	65552883	11	+	27869803	HPAFII	viability after 15 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.1672681718635456	[491]	[452,481,NaN]	-2	hSpCas9	negative selection	9625599
65553163	65553186	11	-	27869803	HPAFII	viability after 15 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.6636700258648943	[190]	[300,22,NaN]	-6	hSpCas9	negative selection	9625600
65553868	65553891	11	+	27869803	HPAFII	viability after 15 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.5621311150548338	[501]	[1131,587,NaN]	6	hSpCas9	negative selection	9625601
65554089	65554112	11	+	27869803	HPAFII	viability after 15 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.1657237325011764	[195]	[413,508,NaN]	9	hSpCas9	negative selection	9625602
65557700	65557723	11	-	27869803	HPAFII	viability after 15 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.668420053756566	[452]	[811,749,NaN]	7	hSpCas9	negative selection	9625603
65552247	65552270	11	-	27869803	ASPC1	viability after 36 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.3937024762262863	[1185]	[636,122,806]	4	hSpCas9	negative selection	9708047
65552860	65552883	11	+	27869803	ASPC1	viability after 36 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.3191221994929606	[1044]	[277,223,757]	3	hSpCas9	negative selection	9708048
65553163	65553186	11	-	27869803	ASPC1	viability after 36 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.6472113754945544	[598]	[193,185,47]	-6	hSpCas9	negative selection	9708049
65553868	65553891	11	+	27869803	ASPC1	viability after 36 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.7482883799373772	[1296]	[549,310,36]	-6	hSpCas9	negative selection	9708050
65554089	65554112	11	+	27869803	ASPC1	viability after 36 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	0.23170686037078428	[508]	[212,324,110]	2	hSpCas9	negative selection	9708051
65557700	65557723	11	-	27869803	ASPC1	viability after 36 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	-0.17955617285731607	[1292]	[252,354,530]	-2	hSpCas9	negative selection	9708052
65552247	65552270	11	-	27869803	PATU8988S	viability after 35 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.14041703602802624	[1001]	[360,528,NaN]	1	hSpCas9	negative selection	9790496
65552860	65552883	11	+	27869803	PATU8988S	viability after 35 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.05739003930183484	[1025]	[425,433,NaN]	0	hSpCas9	negative selection	9790497
65553163	65553186	11	-	27869803	PATU8988S	viability after 35 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.1020690620252221	[515]	[246,198,NaN]	1	hSpCas9	negative selection	9790498
65553868	65553891	11	+	27869803	PATU8988S	viability after 35 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	-0.29883816965698295	[1186]	[441,334,NaN]	-3	hSpCas9	negative selection	9790499
65554089	65554112	11	+	27869803	PATU8988S	viability after 35 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	0.23022096868135158	[414]	[221,169,NaN]	2	hSpCas9	negative selection	9790500
65557700	65557723	11	-	27869803	PATU8988S	viability after 35 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.3044939766978235	[992]	[234,753,NaN]	3	hSpCas9	negative selection	9790501
65552247	65552270	11	-	27869803	PATU8988S	viability after 31 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	0.47551711201711544	[1001]	[401,750,NaN]	6	hSpCas9	negative selection	9872945
65552860	65552883	11	+	27869803	PATU8988S	viability after 31 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	0.5410411777668759	[1025]	[523,685,NaN]	6	hSpCas9	negative selection	9872946
65553163	65553186	11	-	27869803	PATU8988S	viability after 31 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	-0.03608658528266501	[515]	[146,268,NaN]	0	hSpCas9	negative selection	9872947
65553868	65553891	11	+	27869803	PATU8988S	viability after 31 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.10637514572959961	[1186]	[538,471,NaN]	1	hSpCas9	negative selection	9872948
65554089	65554112	11	+	27869803	PATU8988S	viability after 31 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	0.7816752644949931	[414]	[276,293,NaN]	8	hSpCas9	negative selection	9872949
65557700	65557723	11	-	27869803	PATU8988S	viability after 31 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.3593216450838005	[992]	[199,899,NaN]	4	hSpCas9	negative selection	9872950
65552247	65552270	11	-	27869803	HPAFII	viability after 35 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.07273450409978488	[580]	[83,499,NaN]	0	hSpCas9	negative selection	9955394
65552860	65552883	11	+	27869803	HPAFII	viability after 35 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.9359979913977817	[491]	[148,108,NaN]	-5	hSpCas9	negative selection	9955395
65553163	65553186	11	-	27869803	HPAFII	viability after 35 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.80506669970503	[190]	[294,26,NaN]	5	hSpCas9	negative selection	9955396
65553868	65553891	11	+	27869803	HPAFII	viability after 35 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	0.7061240560380975	[501]	[558,251,NaN]	4	hSpCas9	negative selection	9955397
65554089	65554112	11	+	27869803	HPAFII	viability after 35 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.5645662585015552	[195]	[221,373,NaN]	9	hSpCas9	negative selection	9955398
65557700	65557723	11	-	27869803	HPAFII	viability after 35 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	1.1152725192016395	[452]	[469,526,NaN]	7	hSpCas9	negative selection	9955399
65552247	65552270	11	-	27869803	HPAFII	viability after 31 days	CGCTGCCCAACAGATGGCACCGG	LTBP3	ENSG00000168056	-0.3694142263014121	[580]	[160,351,NaN]	-2	hSpCas9	negative selection	10037843
65552860	65552883	11	+	27869803	HPAFII	viability after 31 days	CAATGCACTGTGTACGGGAGGGG	LTBP3	ENSG00000168056	-0.8163615564361362	[491]	[129,185,NaN]	-5	hSpCas9	negative selection	10037844
65553163	65553186	11	-	27869803	HPAFII	viability after 31 days	CTTAACAGCACCCACTGCCAGGG	LTBP3	ENSG00000168056	0.776701344415561	[190]	[331,21,NaN]	5	hSpCas9	negative selection	10037845
65553868	65553891	11	+	27869803	HPAFII	viability after 31 days	GGACGCGCACATTCACCACGGGG	LTBP3	ENSG00000168056	1.15153368825813	[501]	[633,616,NaN]	8	hSpCas9	negative selection	10037846
65554089	65554112	11	+	27869803	HPAFII	viability after 31 days	AAGGCTGCGTGCTGGGCAGGAGG	LTBP3	ENSG00000168056	1.704893033541062	[195]	[304,416,NaN]	9	hSpCas9	negative selection	10037847
65557700	65557723	11	-	27869803	HPAFII	viability after 31 days	TGTCGGGACAGTTGTCAGCAGGG	LTBP3	ENSG00000168056	0.9351556814448988	[452]	[510,458,NaN]	7	hSpCas9	negative selection	10037848
65553712	65553735	11	+	28162770	P31FUJ	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.001576536811260798	[534]	[627]	0	hSpCas9	negative selection	10186978
65547938	65547961	11	+	28162770	P31FUJ	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.49710863221787716	[122]	[203]	5	hSpCas9	negative selection	10186979
65557767	65557790	11	-	28162770	P31FUJ	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.2848813434057628	[138]	[198]	3	hSpCas9	negative selection	10186980
65553779	65553802	11	+	28162770	P31FUJ	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.12538943445975526	[109]	[140]	1	hSpCas9	negative selection	10186981
65553234	65553257	11	-	28162770	P31FUJ	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	-1.3162182126020159	[88]	[41]	-7	hSpCas9	negative selection	10186982
65552877	65552900	11	+	28162770	P31FUJ	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	1.2610124082485823	[97]	[275]	9	hSpCas9	negative selection	10186983
65552353	65552376	11	+	28162770	P31FUJ	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-1.2328022044143783	[41]	[20]	-7	hSpCas9	negative selection	10186984
65552125	65552148	11	-	28162770	P31FUJ	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.42879331023676587	[369]	[322]	-4	hSpCas9	negative selection	10186985
65551406	65551429	11	+	28162770	P31FUJ	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.33498515249864547	[337]	[500]	3	hSpCas9	negative selection	10186986
65547963	65547986	11	+	28162770	P31FUJ	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.4642880811453862	[1564]	[1332]	-4	hSpCas9	negative selection	10186987
65553712	65553735	11	+	28162770	TF1	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	NaN	[NaN]	[236]	1	hSpCas9	negative selection	10356344
65547938	65547961	11	+	28162770	TF1	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	NaN	[NaN]	[376]	1	hSpCas9	negative selection	10356345
65557767	65557790	11	-	28162770	TF1	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	NaN	[NaN]	[142]	1	hSpCas9	negative selection	10356346
65553779	65553802	11	+	28162770	TF1	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	NaN	[NaN]	[110]	1	hSpCas9	negative selection	10356347
65553234	65553257	11	-	28162770	TF1	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	NaN	[NaN]	[48]	1	hSpCas9	negative selection	10356348
65552877	65552900	11	+	28162770	TF1	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	NaN	[NaN]	[158]	1	hSpCas9	negative selection	10356349
65552353	65552376	11	+	28162770	TF1	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	NaN	[NaN]	[0]	1	hSpCas9	negative selection	10356350
65552125	65552148	11	-	28162770	TF1	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	NaN	[NaN]	[277]	1	hSpCas9	negative selection	10356351
65551406	65551429	11	+	28162770	TF1	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	NaN	[NaN]	[251]	1	hSpCas9	negative selection	10356352
65547963	65547986	11	+	28162770	TF1	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	NaN	[NaN]	[730]	1	hSpCas9	negative selection	10356353
65553712	65553735	11	+	28162770	SKM1	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.7553306583767176	[147]	[154]	-5	hSpCas9	negative selection	10525710
65547938	65547961	11	+	28162770	SKM1	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.2507546444133084	[28]	[60]	2	hSpCas9	negative selection	10525711
65557767	65557790	11	-	28162770	SKM1	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.6751603096927343	[55]	[61]	-5	hSpCas9	negative selection	10525712
65553779	65553802	11	+	28162770	SKM1	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.04049477822805958	[32]	[59]	0	hSpCas9	negative selection	10525713
65553234	65553257	11	-	28162770	SKM1	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	1.9593580155026542	[23]	[164]	9	hSpCas9	negative selection	10525714
65552877	65552900	11	+	28162770	SKM1	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	-0.22535739225321383	[40]	[61]	-2	hSpCas9	negative selection	10525715
65552353	65552376	11	+	28162770	SKM1	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-3.143929792909368	[9]	[1]	-9	hSpCas9	negative selection	10525716
65552125	65552148	11	-	28162770	SKM1	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	0.061674184010762856	[70]	[130]	0	hSpCas9	negative selection	10525717
65551406	65551429	11	+	28162770	SKM1	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.06180528447347189	[83]	[154]	0	hSpCas9	negative selection	10525718
65547963	65547986	11	+	28162770	SKM1	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.6182550294829574	[355]	[409]	-5	hSpCas9	negative selection	10525719
65553712	65553735	11	+	28162770	SKM1	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.7553306583767176	[147]	[154]	-5	hSpCas9	negative selection	10695076
65547938	65547961	11	+	28162770	SKM1	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.2507546444133084	[28]	[60]	2	hSpCas9	negative selection	10695077
65557767	65557790	11	-	28162770	SKM1	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.6751603096927343	[55]	[61]	-5	hSpCas9	negative selection	10695078
65553779	65553802	11	+	28162770	SKM1	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.04049477822805958	[32]	[59]	0	hSpCas9	negative selection	10695079
65553234	65553257	11	-	28162770	SKM1	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	1.9593580155026542	[23]	[164]	9	hSpCas9	negative selection	10695080
65552877	65552900	11	+	28162770	SKM1	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	-0.22535739225321383	[40]	[61]	-2	hSpCas9	negative selection	10695081
65552353	65552376	11	+	28162770	SKM1	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-3.143929792909368	[9]	[1]	-9	hSpCas9	negative selection	10695082
65552125	65552148	11	-	28162770	SKM1	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	0.061674184010762856	[70]	[130]	0	hSpCas9	negative selection	10695083
65551406	65551429	11	+	28162770	SKM1	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.06180528447347189	[83]	[154]	0	hSpCas9	negative selection	10695084
65547963	65547986	11	+	28162770	SKM1	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.6182550294829574	[355]	[409]	-5	hSpCas9	negative selection	10695085
65553712	65553735	11	+	28162770	PL21	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.24196612798769435	[537]	[197]	-2	hSpCas9	negative selection	10864442
65547938	65547961	11	+	28162770	PL21	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	-0.2817293932677325	[80]	[28]	-2	hSpCas9	negative selection	10864443
65557767	65557790	11	-	28162770	PL21	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.7998603855106796	[123]	[30]	-5	hSpCas9	negative selection	10864444
65553779	65553802	11	+	28162770	PL21	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	-1.3697159938416277	[94]	[15]	-7	hSpCas9	negative selection	10864445
65553234	65553257	11	-	28162770	PL21	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.049579937913938776	[110]	[49]	0	hSpCas9	negative selection	10864446
65552877	65552900	11	+	28162770	PL21	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.5647120467851764	[159]	[102]	5	hSpCas9	negative selection	10864447
65552353	65552376	11	+	28162770	PL21	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-4.323422341567693	[45]	[0]	-9	hSpCas9	negative selection	10864448
65552125	65552148	11	-	28162770	PL21	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	0.8368171517546316	[273]	[212]	7	hSpCas9	negative selection	10864449
65551406	65551429	11	+	28162770	PL21	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.5145209003233343	[229]	[142]	4	hSpCas9	negative selection	10864450
65547963	65547986	11	+	28162770	PL21	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.688363612546552	[1032]	[278]	-5	hSpCas9	negative selection	10864451
65553712	65553735	11	+	28162770	P31FUJ	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.001576536811260798	[534]	[627]	0	hSpCas9	negative selection	11033808
65547938	65547961	11	+	28162770	P31FUJ	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.49710863221787716	[122]	[203]	5	hSpCas9	negative selection	11033809
65557767	65557790	11	-	28162770	P31FUJ	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.2848813434057628	[138]	[198]	3	hSpCas9	negative selection	11033810
65553779	65553802	11	+	28162770	P31FUJ	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.12538943445975526	[109]	[140]	1	hSpCas9	negative selection	11033811
65553234	65553257	11	-	28162770	P31FUJ	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	-1.3162182126020159	[88]	[41]	-7	hSpCas9	negative selection	11033812
65552877	65552900	11	+	28162770	P31FUJ	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	1.2610124082485823	[97]	[275]	9	hSpCas9	negative selection	11033813
65552353	65552376	11	+	28162770	P31FUJ	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-1.2328022044143783	[41]	[20]	-7	hSpCas9	negative selection	11033814
65552125	65552148	11	-	28162770	P31FUJ	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.42879331023676587	[369]	[322]	-4	hSpCas9	negative selection	11033815
65551406	65551429	11	+	28162770	P31FUJ	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.33498515249864547	[337]	[500]	3	hSpCas9	negative selection	11033816
65547963	65547986	11	+	28162770	P31FUJ	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.4642880811453862	[1564]	[1332]	-4	hSpCas9	negative selection	11033817
65553712	65553735	11	+	28162770	OCIAML5	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.7985171025872626	[237]	[246]	-5	hSpCas9	negative selection	11203174
65547938	65547961	11	+	28162770	OCIAML5	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	1.423211430724544	[43]	[212]	9	hSpCas9	negative selection	11203175
65557767	65557790	11	-	28162770	OCIAML5	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.5629709284148467	[53]	[143]	5	hSpCas9	negative selection	11203176
65553779	65553802	11	+	28162770	OCIAML5	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	-1.2320976203149274	[94]	[72]	-6	hSpCas9	negative selection	11203177
65553234	65553257	11	-	28162770	OCIAML5	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	1.4221083925749973	[42]	[207]	9	hSpCas9	negative selection	11203178
65552877	65552900	11	+	28162770	OCIAML5	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.8418303014103232	[50]	[164]	7	hSpCas9	negative selection	11203179
65552353	65552376	11	+	28162770	OCIAML5	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-4.311498189501295	[10]	[0]	-9	hSpCas9	negative selection	11203180
65552125	65552148	11	-	28162770	OCIAML5	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	0.6851991878258628	[163]	[475]	6	hSpCas9	negative selection	11203181
65551406	65551429	11	+	28162770	OCIAML5	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	-0.00922609833357102	[217]	[390]	0	hSpCas9	negative selection	11203182
65547963	65547986	11	+	28162770	OCIAML5	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.7589571664725154	[779]	[831]	-5	hSpCas9	negative selection	11203183
65553712	65553735	11	+	28162770	EOL1	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.08971292155463528	[914]	[452]	0	hSpCas9	negative selection	11372540
65547938	65547961	11	+	28162770	EOL1	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.821454278606431	[144]	[134]	7	hSpCas9	negative selection	11372541
65557767	65557790	11	-	28162770	EOL1	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.27940740150923704	[310]	[134]	-2	hSpCas9	negative selection	11372542
65553779	65553802	11	+	28162770	EOL1	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	-1.1029329648515724	[158]	[38]	-6	hSpCas9	negative selection	11372543
65553234	65553257	11	-	28162770	EOL1	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.5954241752789684	[200]	[159]	5	hSpCas9	negative selection	11372544
65552877	65552900	11	+	28162770	EOL1	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	-0.35734566151457525	[230]	[94]	-3	hSpCas9	negative selection	11372545
65552353	65552376	11	+	28162770	EOL1	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	1.4186568418405772	[70]	[99]	9	hSpCas9	negative selection	11372546
65552125	65552148	11	-	28162770	EOL1	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	0.8791373118805881	[354]	[343]	7	hSpCas9	negative selection	11372547
65551406	65551429	11	+	28162770	EOL1	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.32415523027977255	[375]	[247]	3	hSpCas9	negative selection	11372548
65547963	65547986	11	+	28162770	EOL1	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.3723049179248812	[1596]	[649]	-3	hSpCas9	negative selection	11372549
65553712	65553735	11	+	28162770	MOLM13	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	0.240054875139883	[663]	[566]	1	hSpCas9	negative selection	11541906
65547938	65547961	11	+	28162770	MOLM13	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.721645973790362	[155]	[185]	5	hSpCas9	negative selection	11541907
65557767	65557790	11	-	28162770	MOLM13	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.7286536137535455	[211]	[253]	5	hSpCas9	negative selection	11541908
65553779	65553802	11	+	28162770	MOLM13	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.3389916483623212	[116]	[106]	2	hSpCas9	negative selection	11541909
65553234	65553257	11	-	28162770	MOLM13	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.5674250550954933	[153]	[164]	4	hSpCas9	negative selection	11541910
65552877	65552900	11	+	28162770	MOLM13	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	-0.5046298820333139	[207]	[105]	-3	hSpCas9	negative selection	11541911
65552353	65552376	11	+	28162770	MOLM13	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-5.0556725745124345	[45]	[0]	-9	hSpCas9	negative selection	11541912
65552125	65552148	11	-	28162770	MOLM13	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.053105293166877454	[385]	[268]	0	hSpCas9	negative selection	11541913
65551406	65551429	11	+	28162770	MOLM13	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	-0.2550010274099045	[339]	[205]	-1	hSpCas9	negative selection	11541914
65547963	65547986	11	+	28162770	MOLM13	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.48771649909696757	[1599]	[824]	-3	hSpCas9	negative selection	11541915
65553712	65553735	11	+	28162770	HEL	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	0.07337318633021939	[643]	[433]	0	hSpCas9	negative selection	11711272
65547938	65547961	11	+	28162770	HEL	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.8595502210735051	[110]	[128]	7	hSpCas9	negative selection	11711273
65557767	65557790	11	-	28162770	HEL	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.6689694205691266	[210]	[84]	-4	hSpCas9	negative selection	11711274
65553779	65553802	11	+	28162770	HEL	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.476380445578237	[100]	[89]	4	hSpCas9	negative selection	11711275
65553234	65553257	11	-	28162770	HEL	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.48965950199596797	[148]	[133]	4	hSpCas9	negative selection	11711276
65552877	65552900	11	+	28162770	HEL	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	1.1055294627275691	[155]	[214]	8	hSpCas9	negative selection	11711277
65552353	65552376	11	+	28162770	HEL	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-5.001117357774367	[49]	[0]	-9	hSpCas9	negative selection	11711278
65552125	65552148	11	-	28162770	HEL	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.5303258769725228	[344]	[152]	-4	hSpCas9	negative selection	11711279
65551406	65551429	11	+	28162770	HEL	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.012312299122827552	[273]	[176]	0	hSpCas9	negative selection	11711280
65547963	65547986	11	+	28162770	HEL	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.6181385412249476	[1202]	[501]	-4	hSpCas9	negative selection	11711281
65553712	65553735	11	+	28162770	MV411	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	0.11291788547166193	[482]	[439]	1	hSpCas9	negative selection	11880638
65547938	65547961	11	+	28162770	MV411	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	-0.17164678155877044	[118]	[88]	-1	hSpCas9	negative selection	11880639
65557767	65557790	11	-	28162770	MV411	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.10059616245350428	[185]	[167]	0	hSpCas9	negative selection	11880640
65553779	65553802	11	+	28162770	MV411	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.5646277266634747	[60]	[75]	5	hSpCas9	negative selection	11880641
65553234	65553257	11	-	28162770	MV411	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	0.04342365876118193	[90]	[78]	0	hSpCas9	negative selection	11880642
65552877	65552900	11	+	28162770	MV411	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.002325052946243966	[127]	[107]	0	hSpCas9	negative selection	11880643
65552353	65552376	11	+	28162770	MV411	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-2.7881863589479456	[40]	[4]	-9	hSpCas9	negative selection	11880644
65552125	65552148	11	-	28162770	MV411	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.9435052319286201	[241]	[105]	-6	hSpCas9	negative selection	11880645
65551406	65551429	11	+	28162770	MV411	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.664918225989948	[294]	[393]	6	hSpCas9	negative selection	11880646
65547963	65547986	11	+	28162770	MV411	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.7281420837273016	[1112]	[565]	-5	hSpCas9	negative selection	11880647
65553712	65553735	11	+	28162770	MONOMAC1	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.8553725341109293	[362]	[229]	-6	hSpCas9	negative selection	12050004
65547938	65547961	11	+	28162770	MONOMAC1	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.46809600234558596	[69]	[110]	4	hSpCas9	negative selection	12050005
65557767	65557790	11	-	28162770	MONOMAC1	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	0.5880652681509227	[111]	[192]	6	hSpCas9	negative selection	12050006
65553779	65553802	11	+	28162770	MONOMAC1	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	-0.33238869995443965	[66]	[60]	-3	hSpCas9	negative selection	12050007
65553234	65553257	11	-	28162770	MONOMAC1	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	-0.3225677291434127	[83]	[76]	-3	hSpCas9	negative selection	12050008
65552877	65552900	11	+	28162770	MONOMAC1	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.39277505332299834	[98]	[148]	4	hSpCas9	negative selection	12050009
65552353	65552376	11	+	28162770	MONOMAC1	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	0.04000235024129539	[27]	[32]	0	hSpCas9	negative selection	12050010
65552125	65552148	11	-	28162770	MONOMAC1	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.5440559229097466	[144]	[113]	-4	hSpCas9	negative selection	12050011
65551406	65551429	11	+	28162770	MONOMAC1	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.2921098662478019	[165]	[232]	3	hSpCas9	negative selection	12050012
65547963	65547986	11	+	28162770	MONOMAC1	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.006430914390755937	[707]	[807]	0	hSpCas9	negative selection	12050013
65553712	65553735	11	+	28162770	OCIAML2	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	0.3186911739851812	[91]	[635]	3	hSpCas9	negative selection	12219370
65547938	65547961	11	+	28162770	OCIAML2	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.40383929267398	[14]	[109]	4	hSpCas9	negative selection	12219371
65557767	65557790	11	-	28162770	OCIAML2	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	-0.4140462968757938	[24]	[103]	-3	hSpCas9	negative selection	12219372
65553779	65553802	11	+	28162770	OCIAML2	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	-0.01996841623259593	[14]	[81]	0	hSpCas9	negative selection	12219373
65553234	65553257	11	-	28162770	OCIAML2	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	1.0883374669460502	[13]	[164]	9	hSpCas9	negative selection	12219374
65552877	65552900	11	+	28162770	OCIAML2	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	0.48962399596508244	[22]	[178]	5	hSpCas9	negative selection	12219375
65552353	65552376	11	+	28162770	OCIAML2	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-2.6405548266844736	[8]	[7]	-9	hSpCas9	negative selection	12219376
65552125	65552148	11	-	28162770	OCIAML2	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	-0.47849194301513165	[45]	[182]	-4	hSpCas9	negative selection	12219377
65551406	65551429	11	+	28162770	OCIAML2	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	-0.18683685924157012	[45]	[223]	-1	hSpCas9	negative selection	12219378
65547963	65547986	11	+	28162770	OCIAML2	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	-0.4667359091376697	[184]	[741]	-4	hSpCas9	negative selection	12219379
65553712	65553735	11	+	28162770	OCIAML3	viability	GCAGAGTGTCCTGAAAGCAGCGG	LTBP3	ENSG00000168056	-0.04103525384744389	[151]	[445]	0	hSpCas9	negative selection	12388736
65547938	65547961	11	+	28162770	OCIAML3	viability	GGGGATGTGACCGGTAGCCGGGG	LTBP3	ENSG00000168056	0.7046506752403521	[24]	[122]	6	hSpCas9	negative selection	12388737
65557767	65557790	11	-	28162770	OCIAML3	viability	GGCCCGCGAGCGCTTCAAGGTGG	LTBP3	ENSG00000168056	1.0968883051460583	[34]	[225]	8	hSpCas9	negative selection	12388738
65553779	65553802	11	+	28162770	OCIAML3	viability	GTGCGGCAGCAGGTGCTGGGAGG	LTBP3	ENSG00000168056	0.6124432371432632	[25]	[119]	5	hSpCas9	negative selection	12388739
65553234	65553257	11	-	28162770	OCIAML3	viability	ACACAGGAGTGCAGAAGCCAGGG	LTBP3	ENSG00000168056	-0.6611218361827	[32]	[62]	-5	hSpCas9	negative selection	12388740
65552877	65552900	11	+	28162770	OCIAML3	viability	GAGGGGCCTAAACTATGGCCAGG	LTBP3	ENSG00000168056	-1.5082777662982794	[48]	[51]	-8	hSpCas9	negative selection	12388741
65552353	65552376	11	+	28162770	OCIAML3	viability	GGTGCTCAGGGCTCACCAGGCGG	LTBP3	ENSG00000168056	-0.9419309437444698	[13]	[21]	-6	hSpCas9	negative selection	12388742
65552125	65552148	11	-	28162770	OCIAML3	viability	GGAGATCTGCCCAGCTGGGAAGG	LTBP3	ENSG00000168056	0.6003704048426882	[51]	[237]	5	hSpCas9	negative selection	12388743
65551406	65551429	11	+	28162770	OCIAML3	viability	GTAGGGCCGGGCAGGAGTCGTGG	LTBP3	ENSG00000168056	0.995094590757917	[57]	[348]	8	hSpCas9	negative selection	12388744
65547963	65547986	11	+	28162770	OCIAML3	viability	GCAGTGGCAGGAGTAGTCAGGGG	LTBP3	ENSG00000168056	0.030608594563365177	[310]	[958]	0	hSpCas9	negative selection	12388745