Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:4038
• Symbol:Lrp4
• Description:LDL receptor related protein 4

DataSource: http://genomecrispr.dkfz.de/#!/results/Lrp4

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
46900304	46900327	11	+	26472758	Jiyoye	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	-0.36149907238767065	[183]	[107]	-3	hSpCas9	negative selection	92379
46890276	46890299	11	-	26472758	Jiyoye	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-0.15225202710814534	[55]	[37]	-1	hSpCas9	negative selection	92380
46899428	46899451	11	-	26472758	Jiyoye	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	1.8316732100337834	[18]	[50]	8	hSpCas9	negative selection	92381
46896914	46896937	11	-	26472758	Jiyoye	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.1743731770914947	[254]	[216]	1	hSpCas9	negative selection	92382
46896260	46896283	11	-	26472758	Jiyoye	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-1.1018382659819843	[184]	[64]	-6	hSpCas9	negative selection	92383
46895234	46895257	11	-	26472758	Jiyoye	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.8391262637210637	[105]	[142]	6	hSpCas9	negative selection	92384
46894616	46894639	11	-	26472758	Jiyoye	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.2847023231317948	[167]	[103]	-2	hSpCas9	negative selection	92385
46893068	46893091	11	-	26472758	Jiyoye	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.12599362896182023	[95]	[78]	1	hSpCas9	negative selection	92386
46893019	46893042	11	+	26472758	Jiyoye	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.4742895773644103	[62]	[65]	3	hSpCas9	negative selection	92387
46892998	46893021	11	-	26472758	Jiyoye	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-0.8407521319377121	[75]	[31]	-5	hSpCas9	negative selection	92388
46900304	46900327	11	+	26472758	KBM7	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.037725889838261764	[666,324]	[144,309]	0	hSpCas9	negative selection	283497
46890276	46890299	11	-	26472758	KBM7	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	0.04776291594003351	[292,402]	[187,158]	0	hSpCas9	negative selection	283498
46899428	46899451	11	-	26472758	KBM7	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.03369175650509859	[290,343]	[81,219]	0	hSpCas9	negative selection	283499
46896914	46896937	11	-	26472758	KBM7	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.4938440414250058	[1045,628]	[663,434]	5	hSpCas9	negative selection	283500
46896260	46896283	11	-	26472758	KBM7	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-1.1701515099196045	[545,351]	[163,27]	-7	hSpCas9	negative selection	283501
46895234	46895257	11	-	26472758	KBM7	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.3590458618160842	[523,365]	[230,294]	4	hSpCas9	negative selection	283502
46894616	46894639	11	-	26472758	KBM7	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.5901471291472272	[680,723]	[217,223]	-5	hSpCas9	negative selection	283503
46893068	46893091	11	-	26472758	KBM7	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.6221636123412038	[572,495]	[416,357]	6	hSpCas9	negative selection	283504
46893019	46893042	11	+	26472758	KBM7	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.6896902879209811	[281,301]	[160,278]	7	hSpCas9	negative selection	283505
46892998	46893021	11	-	26472758	KBM7	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.5045108750564582	[325,152]	[39,36]	-8	hSpCas9	negative selection	283506
46900304	46900327	11	+	26472758	Raji	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.09478349859396593	[229]	[56]	0	hSpCas9	negative selection	474615
46890276	46890299	11	-	26472758	Raji	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	0.3188876405673112	[151]	[43]	3	hSpCas9	negative selection	474616
46899428	46899451	11	-	26472758	Raji	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.5326893701062703	[139]	[46]	5	hSpCas9	negative selection	474617
46896914	46896937	11	-	26472758	Raji	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.210477028337703	[431]	[115]	2	hSpCas9	negative selection	474618
46896260	46896283	11	-	26472758	Raji	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	0.48786381261607487	[168]	[54]	4	hSpCas9	negative selection	474619
46895234	46895257	11	-	26472758	Raji	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.22155455529291074	[254]	[68]	2	hSpCas9	negative selection	474620
46894616	46894639	11	-	26472758	Raji	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	0.32627851247382056	[353]	[102]	3	hSpCas9	negative selection	474621
46893068	46893091	11	-	26472758	Raji	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.43363561775995985	[290]	[49]	-4	hSpCas9	negative selection	474622
46893019	46893042	11	+	26472758	Raji	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.9243174342432208	[192]	[84]	8	hSpCas9	negative selection	474623
46892998	46893021	11	-	26472758	Raji	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.3520480832636976	[120]	[10]	-7	hSpCas9	negative selection	474624
46900304	46900327	11	+	26472758	K562	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	-1.306027891354205	[412]	[140]	-6	hSpCas9	negative selection	665733
46890276	46890299	11	-	26472758	K562	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-3.46253429743332	[221]	[16]	-8	hSpCas9	negative selection	665734
46899428	46899451	11	-	26472758	K562	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.10146077382440394	[264]	[239]	0	hSpCas9	negative selection	665735
46896914	46896937	11	-	26472758	K562	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.09402848518969775	[595]	[536]	0	hSpCas9	negative selection	665736
46896260	46896283	11	-	26472758	K562	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.4076579689132463	[406]	[258]	-3	hSpCas9	negative selection	665737
46895234	46895257	11	-	26472758	K562	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	-0.7622450026145638	[433]	[215]	-4	hSpCas9	negative selection	665738
46894616	46894639	11	-	26472758	K562	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.9437850074941744	[555]	[243]	-5	hSpCas9	negative selection	665739
46893068	46893091	11	-	26472758	K562	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.4182057456844288	[352]	[222]	-3	hSpCas9	negative selection	665740
46893019	46893042	11	+	26472758	K562	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.33661242587619344	[196]	[209]	2	hSpCas9	negative selection	665741
46892998	46893021	11	-	26472758	K562	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-2.7435084400329783	[118]	[14]	-8	hSpCas9	negative selection	665742
46898945	46898968	11	-	26627737	DLD1	viability	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.04990874287588043	[1289]	[432,584,189]	0	hSpCas9	negative selection	778674
46899407	46899430	11	-	26627737	DLD1	viability	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-1.134058626221008	[313]	[63,22,45]	-7	hSpCas9	negative selection	778675
46899934	46899957	11	-	26627737	DLD1	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.6289239518144971	[402]	[184,292,121]	6	hSpCas9	negative selection	778676
46900301	46900324	11	-	26627737	DLD1	viability	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.46074641462139887	[1088]	[670,488,275]	5	hSpCas9	negative selection	778677
46902825	46902848	11	+	26627737	DLD1	viability	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	1.0850767436503803	[190]	[220,134,37]	8	hSpCas9	negative selection	778678
46918323	46918346	11	+	26627737	DLD1	viability	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.4476845849782071	[602]	[171,344,257]	4	hSpCas9	negative selection	778679
46898945	46898968	11	-	26627737	GBM cells	viability after 5 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.5956623893783651	[347]	[120,125]	-7	hSpCas9	negative selection	860989
46899407	46899430	11	-	26627737	GBM cells	viability after 5 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.28078451022933015	[131]	[63,107]	4	hSpCas9	negative selection	860990
46899934	46899957	11	-	26627737	GBM cells	viability after 5 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.11402518082181265	[223]	[91,129]	-2	hSpCas9	negative selection	860991
46900301	46900324	11	-	26627737	GBM cells	viability after 5 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.457010530724934	[525]	[194,215]	-6	hSpCas9	negative selection	860992
46902825	46902848	11	+	26627737	GBM cells	viability after 5 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	0.08236001598161669	[117]	[76,56]	1	hSpCas9	negative selection	860993
46918323	46918346	11	+	26627737	GBM cells	viability after 5 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.5528237293243332	[285]	[251,197]	7	hSpCas9	negative selection	860994
46898945	46898968	11	-	26627737	GBM cells	viability after 13 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.6119578617798735	[347]	[181,75]	-6	hSpCas9	negative selection	943304
46899407	46899430	11	-	26627737	GBM cells	viability after 13 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.6000421852152633	[131]	[123,95]	7	hSpCas9	negative selection	943305
46899934	46899957	11	-	26627737	GBM cells	viability after 13 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.019244963866607068	[223]	[190,67]	0	hSpCas9	negative selection	943306
46900301	46900324	11	-	26627737	GBM cells	viability after 13 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.3752150802459676	[525]	[224,215]	-4	hSpCas9	negative selection	943307
46902825	46902848	11	+	26627737	GBM cells	viability after 13 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.45432635714141223	[117]	[54,39]	-5	hSpCas9	negative selection	943308
46918323	46918346	11	+	26627737	GBM cells	viability after 13 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-0.10614986431817097	[285]	[136,149]	-1	hSpCas9	negative selection	943309
46898945	46898968	11	-	26627737	GBM cells	viability after 21 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-1.03705889145333	[347]	[88,94]	-7	hSpCas9	negative selection	1025619
46899407	46899430	11	-	26627737	GBM cells	viability after 21 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.7868000216026825	[131]	[141,106]	7	hSpCas9	negative selection	1025620
46899934	46899957	11	-	26627737	GBM cells	viability after 21 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.2583044725405549	[223]	[155,135]	2	hSpCas9	negative selection	1025621
46900301	46900324	11	-	26627737	GBM cells	viability after 21 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.12068124560728977	[525]	[254,269]	-1	hSpCas9	negative selection	1025622
46902825	46902848	11	+	26627737	GBM cells	viability after 21 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.2769109408055235	[117]	[54,50]	-3	hSpCas9	negative selection	1025623
46918323	46918346	11	+	26627737	GBM cells	viability after 21 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.307910312955136	[285]	[195,188]	3	hSpCas9	negative selection	1025624
46898945	46898968	11	-	26627737	RPE1	viability after 9 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.6077961318497127	[1320]	[273,267]	-4	hSpCas9	negative selection	1107934
46899407	46899430	11	-	26627737	RPE1	viability after 9 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.6571513658293202	[1100]	[194,248]	-5	hSpCas9	negative selection	1107935
46899934	46899957	11	-	26627737	RPE1	viability after 9 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.1959955274999965	[1169]	[464,360]	1	hSpCas9	negative selection	1107936
46900301	46900324	11	-	26627737	RPE1	viability after 9 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.09708410782783039	[1885]	[717,519]	0	hSpCas9	negative selection	1107937
46902825	46902848	11	+	26627737	RPE1	viability after 9 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	0.14183320145406042	[371]	[93,172]	1	hSpCas9	negative selection	1107938
46918323	46918346	11	+	26627737	RPE1	viability after 9 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	1.1461817119319402	[844]	[619,540]	7	hSpCas9	negative selection	1107939
46898945	46898968	11	-	26627737	RPE1	viability after 12 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.8673591386670944	[1320]	[212,174]	-5	hSpCas9	negative selection	1190249
46899407	46899430	11	-	26627737	RPE1	viability after 12 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.5933569482785431	[1100]	[231,157]	-4	hSpCas9	negative selection	1190250
46899934	46899957	11	-	26627737	RPE1	viability after 12 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.45287393015260147	[1169]	[455,402]	3	hSpCas9	negative selection	1190251
46900301	46900324	11	-	26627737	RPE1	viability after 12 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.043456098423520606	[1885]	[681,352]	0	hSpCas9	negative selection	1190252
46902825	46902848	11	+	26627737	RPE1	viability after 12 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-1.414778411761776	[371]	[53,19]	-7	hSpCas9	negative selection	1190253
46918323	46918346	11	+	26627737	RPE1	viability after 12 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.46674268445923495	[844]	[389,232]	3	hSpCas9	negative selection	1190254
46898945	46898968	11	-	26627737	RPE1	viability after 15 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-1.1833054809171866	[1320]	[189,139]	-6	hSpCas9	negative selection	1272564
46899407	46899430	11	-	26627737	RPE1	viability after 15 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.6272584507601722	[1100]	[165,235]	-4	hSpCas9	negative selection	1272565
46899934	46899957	11	-	26627737	RPE1	viability after 15 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.7552142996787308	[1169]	[522,592]	4	hSpCas9	negative selection	1272566
46900301	46900324	11	-	26627737	RPE1	viability after 15 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.32632654056612864	[1885]	[1038,311]	2	hSpCas9	negative selection	1272567
46902825	46902848	11	+	26627737	RPE1	viability after 15 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.7035536240631999	[371]	[57,70]	-4	hSpCas9	negative selection	1272568
46918323	46918346	11	+	26627737	RPE1	viability after 15 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.7049654589513334	[844]	[521,261]	4	hSpCas9	negative selection	1272569
46898945	46898968	11	-	26627737	RPE1	viability after 18 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-1.4495523563411545	[1320]	[174,82]	-7	hSpCas9	negative selection	1354879
46899407	46899430	11	-	26627737	RPE1	viability after 18 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.4633705703845908	[1100]	[302,121]	-3	hSpCas9	negative selection	1354880
46899934	46899957	11	-	26627737	RPE1	viability after 18 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.715318456612573	[1169]	[471,567]	4	hSpCas9	negative selection	1354881
46900301	46900324	11	-	26627737	RPE1	viability after 18 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.5706791442201518	[1885]	[1030,461]	3	hSpCas9	negative selection	1354882
46902825	46902848	11	+	26627737	RPE1	viability after 18 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	0.3897143855719082	[371]	[175,83]	2	hSpCas9	negative selection	1354883
46918323	46918346	11	+	26627737	RPE1	viability after 18 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.9324551757720843	[844]	[528,334]	5	hSpCas9	negative selection	1354884
46898945	46898968	11	-	26627737	HeLa	viability after 8 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-1.457654453410611	[566]	[111,81,80]	-9	hSpCas9	negative selection	1437194
46899407	46899430	11	-	26627737	HeLa	viability after 8 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.465707309092544	[213]	[157,86,145]	4	hSpCas9	negative selection	1437195
46899934	46899957	11	-	26627737	HeLa	viability after 8 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.7209187134100976	[216]	[299,121,81]	6	hSpCas9	negative selection	1437196
46900301	46900324	11	-	26627737	HeLa	viability after 8 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.20513630432006114	[563]	[420,113,339]	2	hSpCas9	negative selection	1437197
46902825	46902848	11	+	26627737	HeLa	viability after 8 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	1.6865928098402074	[108]	[138,177,138]	9	hSpCas9	negative selection	1437198
46918323	46918346	11	+	26627737	HeLa	viability after 8 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-0.11460704812945854	[663]	[374,235,216]	-1	hSpCas9	negative selection	1437199
46898945	46898968	11	-	26627737	HeLa	viability after 12 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.5564715724839973	[566]	[175,210,85]	-5	hSpCas9	negative selection	1519509
46899407	46899430	11	-	26627737	HeLa	viability after 12 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.655006689839311	[213]	[141,118,158]	5	hSpCas9	negative selection	1519510
46899934	46899957	11	-	26627737	HeLa	viability after 12 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.4585456117851411	[216]	[104,171,86]	4	hSpCas9	negative selection	1519511
46900301	46900324	11	-	26627737	HeLa	viability after 12 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.14676800468375328	[563]	[89,382,282]	1	hSpCas9	negative selection	1519512
46902825	46902848	11	+	26627737	HeLa	viability after 12 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	1.5607606942897356	[108]	[248,104,50]	9	hSpCas9	negative selection	1519513
46918323	46918346	11	+	26627737	HeLa	viability after 12 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.11522018429651981	[663]	[541,247,113]	1	hSpCas9	negative selection	1519514
46898945	46898968	11	-	26627737	HeLa	viability after 15 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.970131072526071	[566]	[113,103,136]	-7	hSpCas9	negative selection	1601824
46899407	46899430	11	-	26627737	HeLa	viability after 15 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.27889729100492666	[213]	[62,62,90]	-2	hSpCas9	negative selection	1601825
46899934	46899957	11	-	26627737	HeLa	viability after 15 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	1.2533970687465033	[216]	[113,260,261]	8	hSpCas9	negative selection	1601826
46900301	46900324	11	-	26627737	HeLa	viability after 15 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.6292666318811505	[563]	[493,306,254]	5	hSpCas9	negative selection	1601827
46902825	46902848	11	+	26627737	HeLa	viability after 15 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	1.5025288995457817	[108]	[63,175,138]	8	hSpCas9	negative selection	1601828
46918323	46918346	11	+	26627737	HeLa	viability after 15 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-1.3361735354596371	[663]	[158,96,60]	-8	hSpCas9	negative selection	1601829
46898945	46898968	11	-	26627737	HeLa	viability after 18 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.980124005557253	[566]	[70,90,136]	-7	hSpCas9	negative selection	1684139
46899407	46899430	11	-	26627737	HeLa	viability after 18 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.30814873311677216	[213]	[41,48,90]	-3	hSpCas9	negative selection	1684140
46899934	46899957	11	-	26627737	HeLa	viability after 18 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	1.2435662679837078	[216]	[76,211,261]	8	hSpCas9	negative selection	1684141
46900301	46900324	11	-	26627737	HeLa	viability after 18 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.5945589742500542	[563]	[323,242,254]	5	hSpCas9	negative selection	1684142
46902825	46902848	11	+	26627737	HeLa	viability after 18 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	1.4719572949638553	[108]	[39,142,138]	8	hSpCas9	negative selection	1684143
46918323	46918346	11	+	26627737	HeLa	viability after 18 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-1.3496664158011389	[663]	[104,79,60]	-8	hSpCas9	negative selection	1684144
46898945	46898968	11	-	26627737	HCT116	viability after 6 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.6760168644422979	[841]	[487,58]	4	hSpCas9	negative selection	1766454
46899407	46899430	11	-	26627737	HCT116	viability after 6 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-1.4559881146557256	[648]	[100,1]	-7	hSpCas9	negative selection	1766455
46899934	46899957	11	-	26627737	HCT116	viability after 6 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.9781261503974839	[892]	[78,66]	-5	hSpCas9	negative selection	1766456
46900301	46900324	11	-	26627737	HCT116	viability after 6 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.10213932756960142	[2483]	[306,480]	0	hSpCas9	negative selection	1766457
46902825	46902848	11	+	26627737	HCT116	viability after 6 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	3.5417596837276593	[35]	[72,61]	9	hSpCas9	negative selection	1766458
46918323	46918346	11	+	26627737	HCT116	viability after 6 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	1.2731424873452986	[766]	[565,139]	6	hSpCas9	negative selection	1766459
46898945	46898968	11	-	26627737	HCT116	viability after 8 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.24450437761535215	[574]	[243,296,260]	-3	hSpCas9	negative selection	1848769
46899407	46899430	11	-	26627737	HCT116	viability after 8 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.24249306970034842	[244]	[172,115,189]	2	hSpCas9	negative selection	1848770
46899934	46899957	11	-	26627737	HCT116	viability after 8 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.6561019269323299	[430]	[146,148,155]	-7	hSpCas9	negative selection	1848771
46900301	46900324	11	-	26627737	HCT116	viability after 8 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.39826584654457853	[732]	[247,333,335]	-5	hSpCas9	negative selection	1848772
46902825	46902848	11	+	26627737	HCT116	viability after 8 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-1.0551440360160185	[320]	[96,107,50]	-8	hSpCas9	negative selection	1848773
46918323	46918346	11	+	26627737	HCT116	viability after 8 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.3148296419500059	[374]	[285,261,223]	3	hSpCas9	negative selection	1848774
46898945	46898968	11	-	26627737	HCT116	viability after 9 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.12309781280135851	[841]	[268,156]	-1	hSpCas9	negative selection	1931084
46899407	46899430	11	-	26627737	HCT116	viability after 9 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-1.4133180180471359	[648]	[73,57]	-7	hSpCas9	negative selection	1931085
46899934	46899957	11	-	26627737	HCT116	viability after 9 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-1.3867356611091384	[892]	[179,20]	-7	hSpCas9	negative selection	1931086
46900301	46900324	11	-	26627737	HCT116	viability after 9 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.2194350553138591	[2483]	[893,675]	1	hSpCas9	negative selection	1931087
46902825	46902848	11	+	26627737	HCT116	viability after 9 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	2.2684822403113767	[35]	[90,10]	9	hSpCas9	negative selection	1931088
46918323	46918346	11	+	26627737	HCT116	viability after 9 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-0.46556918551669846	[766]	[130,161]	-3	hSpCas9	negative selection	1931089
46898945	46898968	11	-	26627737	HCT116	viability after 12 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.22237544616222804	[574]	[289,245,237]	-2	hSpCas9	negative selection	2013399
46899407	46899430	11	-	26627737	HCT116	viability after 12 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.07894964520335385	[244]	[103,110,151]	-1	hSpCas9	negative selection	2013400
46899934	46899957	11	-	26627737	HCT116	viability after 12 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.10110831263932307	[430]	[189,71,369]	-1	hSpCas9	negative selection	2013401
46900301	46900324	11	-	26627737	HCT116	viability after 12 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.026107687114265588	[732]	[314,193,626]	0	hSpCas9	negative selection	2013402
46902825	46902848	11	+	26627737	HCT116	viability after 12 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-1.226978099106859	[320]	[92,56,63]	-8	hSpCas9	negative selection	2013403
46918323	46918346	11	+	26627737	HCT116	viability after 12 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.5552486156841603	[374]	[226,361,286]	5	hSpCas9	negative selection	2013404
46898945	46898968	11	-	26627737	HCT116	viability after 15 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.6671320936602229	[574]	[305,137,191]	-6	hSpCas9	negative selection	2095714
46899407	46899430	11	-	26627737	HCT116	viability after 15 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.32559620085581586	[244]	[130,86,120]	-3	hSpCas9	negative selection	2095715
46899934	46899957	11	-	26627737	HCT116	viability after 15 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.2607251583377106	[430]	[192,123,299]	-3	hSpCas9	negative selection	2095716
46900301	46900324	11	-	26627737	HCT116	viability after 15 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.11668084322239491	[732]	[239,292,610]	-1	hSpCas9	negative selection	2095717
46902825	46902848	11	+	26627737	HCT116	viability after 15 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.8809352004137785	[320]	[131,55,115]	-7	hSpCas9	negative selection	2095718
46918323	46918346	11	+	26627737	HCT116	viability after 15 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.5158283501604755	[374]	[325,293,305]	5	hSpCas9	negative selection	2095719
46898945	46898968	11	-	26627737	HCT116	viability after 18 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.7311088703422516	[574]	[81,128,299]	-6	hSpCas9	negative selection	2178029
46899407	46899430	11	-	26627737	HCT116	viability after 18 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.09516934574584585	[244]	[110,124,94]	-1	hSpCas9	negative selection	2178030
46899934	46899957	11	-	26627737	HCT116	viability after 18 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.03899407838493707	[430]	[233,87,333]	0	hSpCas9	negative selection	2178031
46900301	46900324	11	-	26627737	HCT116	viability after 18 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.17673936644400823	[732]	[145,266,540]	-2	hSpCas9	negative selection	2178032
46902825	46902848	11	+	26627737	HCT116	viability after 18 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.8108940066679311	[320]	[105,75,83]	-6	hSpCas9	negative selection	2178033
46918323	46918346	11	+	26627737	HCT116	viability after 18 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.5395478165007594	[374]	[187,341,254]	4	hSpCas9	negative selection	2178034
46918348	46918372	11	-	24717434	HeLa	essential genes for diphteria toxin toxicity	GCAGTGGGGCGCGCTGCTGCTTGG	LRP4	ENSG00000134569	1.5314674654174725	[851,894,864]	[0,0,0]	4	hSpCas9	positive selection	2381085
46902899	46902924	11	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CCAGCAGCCCCGAGTGTGCTTGTGG	LRP4	ENSG00000134569	-1.1099514499216792	[6080,4689,5582]	[0,0,0]	-8	hSpCas9	positive selection	2381086
46902895	46902920	11	-	24717434	HeLa	essential genes for diphteria toxin toxicity	CAGCCCCGAGTGTGCTTGTGGTCGG	LRP4	ENSG00000134569	-0.5145194262308863	[3803,3756,3246]	[0,0,0]	-4	hSpCas9	positive selection	2381087
46918348	46918372	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	GCAGTGGGGCGCGCTGCTGCTTGG	LRP4	ENSG00000134569	1.5311984200120132	[851,894,864]	[0,0,0]	3	hSpCas9	positive selection	2382343
46902899	46902924	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CCAGCAGCCCCGAGTGTGCTTGTGG	LRP4	ENSG00000134569	-1.1097645694538933	[6080,4689,5582]	[0,0,0]	-9	hSpCas9	positive selection	2382344
46902895	46902920	11	-	24717434	HeLa	essential genes for PA/LFnDTA toxicity	CAGCCCCGAGTGTGCTTGTGGTCGG	LRP4	ENSG00000134569	-0.5150600992886243	[3803,3756,3246]	[0,0,0]	-5	hSpCas9	positive selection	2382345
46872138	46872161	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CCTAGCTACTTGGGAGGCTGCGG	LRP4	ENSG00000134569	2.3677236295083457	[37,27]	[69,1]	7	dCas9-VP64	positive selection	2412122
46894032	46894055	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAGGCATGCGCCACCACGCCCGG	LRP4	ENSG00000134569	0.7395023947734947	[14,26]	[11,2]	3	dCas9-VP64	positive selection	2436190
46888167	46888190	11	+	25494202	A375	resistance to PLX-4720 (puromycin)	CAAAAATTAGCTGGGTGTGGTAG	LRP4	ENSG00000134569	-2.5797701712444865	[504,29]	[12,4]	-9	dCas9-VP64	positive selection	2473365
46872138	46872161	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CCTAGCTACTTGGGAGGCTGCGG	LRP4	ENSG00000134569	0.1906181633953845	[24,86]	[25,14]	1	dCas9-VP64	positive selection	2507377
46894032	46894055	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAGGCATGCGCCACCACGCCCGG	LRP4	ENSG00000134569	0.19409034858978108	[82,214]	[36,71]	1	dCas9-VP64	positive selection	2531445
46888167	46888190	11	+	25494202	A375	resistance to PLX-4720 (zeocin)	CAAAAATTAGCTGGGTGTGGTAG	LRP4	ENSG00000134569	0.3593778947128078	[15,191]	[23,59]	3	dCas9-VP64	positive selection	2568620
46890023	46890046	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	ATAGCGCTAACAAATTTACGGGG	LRP4	ENSG00000134569	0.7188355696795043	[4,4]	[5,8]	9	hSpCas9	positive selection	3000000
46894740	46894763	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GCAGCAGTGTGTACTCAGAGCGG	LRP4	ENSG00000134569	0.6266862490873861	[4,3]	[4,6]	9	hSpCas9	positive selection	3000001
46883881	46883904	11	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GGTTCCACCACGATGTCCCGAGG	LRP4	ENSG00000134569	-0.4730235100567357	[1,1]	[1,0]	-6	hSpCas9	positive selection	3000002
46902835	46902858	11	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	GTACCTGCATCCCTGCCCAGTGG	LRP4	ENSG00000134569	0.5472673963307927	[3,3]	[3,5]	9	hSpCas9	positive selection	3000003
46890023	46890046	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	ATAGCGCTAACAAATTTACGGGG	LRP4	ENSG00000134569	0.4001093885536587	[4,4]	[4,4]	7	hSpCas9	positive selection	3067858
46894740	46894763	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GCAGCAGTGTGTACTCAGAGCGG	LRP4	ENSG00000134569	0.29345076316727503	[4,4]	[4,2]	5	hSpCas9	positive selection	3067859
46883881	46883904	11	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GGTTCCACCACGATGTCCCGAGG	LRP4	ENSG00000134569	-0.3129145470664376	[1,1]	[1,0]	-5	hSpCas9	positive selection	3067860
46902835	46902858	11	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	GTACCTGCATCCCTGCCCAGTGG	LRP4	ENSG00000134569	0.5862073963227289	[3,3]	[4,3]	8	hSpCas9	positive selection	3067861
46899950	46899973		+	24336571	A375	resistance to PLX after 7 days	ACTCGTCCTCCTCACACTCCCGG	LRP4	ENSG00000134569	-0.03812099126165858	[28,22]	[22,26]	-1	hSpCas9	positive selection	3125209
46900313	46900336		-	24336571	A375	resistance to PLX after 7 days	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.38577897594164745	[18,17]	[14,12]	-9	hSpCas9	positive selection	3125210
46899950	46899973		+	24336571	A375	resistance to PLX after 14 days	ACTCGTCCTCCTCACACTCCCGG	LRP4	ENSG00000134569	0.7053197854091338	[31,30]	[24,23]	6	hSpCas9	positive selection	3183002
46900313	46900336		-	24336571	A375	resistance to PLX after 14 days	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.7030044783473547	[15,22]	[4,5]	-7	hSpCas9	positive selection	3183003
46899950	46899973		+	24336571	A375	viability after 7 days	ACTCGTCCTCCTCACACTCCCGG	LRP4	ENSG00000134569	0.48533683759338675	[18]	[28,22]	7	hSpCas9	negative selection	3240795
46900313	46900336		-	24336571	A375	viability after 7 days	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.49654067552991366	[13]	[18,17]	7	hSpCas9	negative selection	3240796
46899950	46899973		+	24336571	A375	viability after 14 days	ACTCGTCCTCCTCACACTCCCGG	LRP4	ENSG00000134569	0.7886272109692195	[18]	[31,30]	8	hSpCas9	negative selection	3298588
46900313	46900336		-	24336571	A375	viability after 14 days	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.6128777503182395	[13]	[15,22]	7	hSpCas9	negative selection	3298589
46899934	46899957	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	1.3504356158373165	[59,59]	[0,0]	6	hSpCas9	positive selection	3377575
46899901	46899924	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.7181674003378036	[92,92]	[0,0]	3	hSpCas9	positive selection	3377576
46900336	46900359	11	-	27383988	293T	resistance to West Nile virus (flavivirus)	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-1.0735906666687818	[321,321]	[0,0]	-7	hSpCas9	positive selection	3377577
46890023	46890046	11	-	26780180	HT29	viability (Avana library 4 designs)	ATAGCGCTAACAAATTTACGGGG	LRP4	ENSG00000134569	0.214064265125456	[]	[]	0	hSpCas9	negative selection	3437569
46894739	46894762	11	+	26780180	HT29	viability (Avana library 4 designs)	GCAGCAGTGTGTACTCAGAGCGG	LRP4	ENSG00000134569	-0.122885228563185	[]	[]	-2	hSpCas9	negative selection	3437570
46883880	46883903	11	+	26780180	HT29	viability (Avana library 4 designs)	GGTTCCACCACGATGTCCCGAGG	LRP4	ENSG00000134569	1.1821048147476	[]	[]	4	hSpCas9	negative selection	3437571
46902835	46902858	11	-	26780180	HT29	viability (Avana library 4 designs)	GTACCTGCATCCCTGCCCAGTGG	LRP4	ENSG00000134569	1.76979025763174	[]	[]	6	hSpCas9	negative selection	3437572
46890023	46890046	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	ATAGCGCTAACAAATTTACGGGG	LRP4	ENSG00000134569	-3.02198031298931	[]	[]	-4	hSpCas9	negative selection	3526355
46902835	46902858	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	GTACCTGCATCCCTGCCCAGTGG	LRP4	ENSG00000134569	3.18635943710377	[]	[]	5	hSpCas9	negative selection	3526356
46894739	46894762	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GCAGCAGTGTGTACTCAGAGCGG	LRP4	ENSG00000134569	3.81105844177866	[]	[]	6	hSpCas9	negative selection	3526357
46883880	46883903	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GGTTCCACCACGATGTCCCGAGG	LRP4	ENSG00000134569	0.965009421166435	[]	[]	1	hSpCas9	negative selection	3526358
46899954	46899977	11	+	26780180	A375	viability (Avana lentiCRISPRv2)	GTCCTCCTCACACTCCCGGGGGG	LRP4	ENSG00000134569	-0.397516329904429	[]	[]	0	hSpCas9	negative selection	3526359
46895953	46895976	11	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTGTGCCCAGAAGTGCCAGATGG	LRP4	ENSG00000134569	2.98575385151395	[]	[]	4	hSpCas9	negative selection	3526360
46890023	46890046	11	-	26780180	A375	viability (Avana lentiGuide)	ATAGCGCTAACAAATTTACGGGG	LRP4	ENSG00000134569	3.94279677850867	[]	[]	4	hSpCas9	negative selection	3635014
46902835	46902858	11	-	26780180	A375	viability (Avana lentiGuide)	GTACCTGCATCCCTGCCCAGTGG	LRP4	ENSG00000134569	1.73258995354076	[]	[]	2	hSpCas9	negative selection	3635015
46894739	46894762	11	+	26780180	A375	viability (Avana lentiGuide)	GCAGCAGTGTGTACTCAGAGCGG	LRP4	ENSG00000134569	-0.162235166569834	[]	[]	0	hSpCas9	negative selection	3635016
46883880	46883903	11	+	26780180	A375	viability (Avana lentiGuide)	GGTTCCACCACGATGTCCCGAGG	LRP4	ENSG00000134569	17.8193717139835	[]	[]	8	hSpCas9	negative selection	3635017
46899954	46899977	11	+	26780180	A375	viability (Avana lentiGuide)	GTCCTCCTCACACTCCCGGGGGG	LRP4	ENSG00000134569	0.982565067511092	[]	[]	1	hSpCas9	negative selection	3635018
46895953	46895976	11	-	26780180	A375	viability (Avana lentiGuide)	CTGTGCCCAGAAGTGCCAGATGG	LRP4	ENSG00000134569	-5.02482464510785	[]	[]	-8	hSpCas9	negative selection	3635019
46890023	46890046	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	ATAGCGCTAACAAATTTACGGGG	LRP4	ENSG00000134569	-0.3574219814526447	[7]	[6,4]	-5	hSpCas9	positive selection	3743673
46902835	46902858	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTACCTGCATCCCTGCCCAGTGG	LRP4	ENSG00000134569	-0.11712599910610644	[4]	[5,2]	-2	hSpCas9	positive selection	3743674
46894739	46894762	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GCAGCAGTGTGTACTCAGAGCGG	LRP4	ENSG00000134569	0.20456232056576173	[4]	[5,5]	5	hSpCas9	positive selection	3743675
46883880	46883903	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GGTTCCACCACGATGTCCCGAGG	LRP4	ENSG00000134569	-0.03657761861090991	[3]	[3,3]	0	hSpCas9	positive selection	3743676
46899954	46899977	11	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	GTCCTCCTCACACTCCCGGGGGG	LRP4	ENSG00000134569	0.15451389212774938	[4]	[4,4]	4	hSpCas9	positive selection	3743677
46895953	46895976	11	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTGTGCCCAGAAGTGCCAGATGG	LRP4	ENSG00000134569	0.20511574326515536	[5]	[7,5]	6	hSpCas9	positive selection	3743678
46890023	46890046	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	ATAGCGCTAACAAATTTACGGGG	LRP4	ENSG00000134569	0.17624840340485778	[6]	[6,6]	4	hSpCas9	positive selection	3852280
46902835	46902858	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTACCTGCATCCCTGCCCAGTGG	LRP4	ENSG00000134569	-0.5959265914191779	[5]	[3,1]	-6	hSpCas9	positive selection	3852281
46894739	46894762	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GCAGCAGTGTGTACTCAGAGCGG	LRP4	ENSG00000134569	0.2893562009283298	[5]	[5,5]	7	hSpCas9	positive selection	3852282
46883880	46883903	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GGTTCCACCACGATGTCCCGAGG	LRP4	ENSG00000134569	-0.6053536111518069	[4]	[1,1]	-6	hSpCas9	positive selection	3852283
46899954	46899977	11	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	GTCCTCCTCACACTCCCGGGGGG	LRP4	ENSG00000134569	-0.17313477623336995	[5]	[4,2]	-2	hSpCas9	positive selection	3852284
46895953	46895976	11	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTGTGCCCAGAAGTGCCAGATGG	LRP4	ENSG00000134569	0.319334241159415	[6]	[6,6]	8	hSpCas9	positive selection	3852285
46900313	46900336	11	-	26780180	A375	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.761838056843185	[]	[]	3	hSpCas9	negative selection	3957932
46899480	46899503	11	-	26780180	A375	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	1.05711071988254	[]	[]	5	hSpCas9	negative selection	3957933
46899901	46899924	11	-	26780180	A375	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	1.22880673382529	[]	[]	6	hSpCas9	negative selection	3957934
46900336	46900359	11	-	26780180	A375	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	1.02275271964586	[]	[]	5	hSpCas9	negative selection	3957935
46899934	46899957	11	-	26780180	A375	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.288968010466018	[]	[]	0	hSpCas9	negative selection	3957936
46899453	46899476	11	+	26780180	A375	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	1.08524853110253	[]	[]	5	hSpCas9	negative selection	3957937
46900313	46900336	11	-	26780180	HT29	viability (GeCKOv2 library)	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.388551568194016	[]	[]	1	hSpCas9	negative selection	4065898
46899480	46899503	11	-	26780180	HT29	viability (GeCKOv2 library)	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.58776380822532	[]	[]	2	hSpCas9	negative selection	4065899
46899901	46899924	11	-	26780180	HT29	viability (GeCKOv2 library)	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	1.63715369075255	[]	[]	8	hSpCas9	negative selection	4065900
46900336	46900359	11	-	26780180	HT29	viability (GeCKOv2 library)	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.528143616884977	[]	[]	1	hSpCas9	negative selection	4065901
46899934	46899957	11	-	26780180	HT29	viability (GeCKOv2 library)	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.312165572186298	[]	[]	0	hSpCas9	negative selection	4065902
46899453	46899476	11	+	26780180	HT29	viability (GeCKOv2 library)	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.0998308499636787	[]	[]	-3	hSpCas9	negative selection	4065903
46899950	46899973	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	ACTCGTCCTCCTCACACTCCCGG	LRP4	ENSG00000134569	0.3681205309646356	[4]	[3,4]	8	hSpCas9	positive selection	4149330
46900313	46900336	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.01340180918356687	[4]	[2,2]	0	hSpCas9	positive selection	4149331
46899950	46899973	11	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	ACTCGTCCTCCTCACACTCCCGG	LRP4	ENSG00000134569	-0.6603059193769824	[4]	[1,0,1,0]	-8	hSpCas9	positive selection	4213352
46900313	46900336	11	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.08371339667240246	[2]	[0,0,4,0]	0	hSpCas9	positive selection	4213353
46899453	46899476	11	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	0.04760753349871871	[3]	[2,2]	1	hSpCas9	positive selection	4280880
46899480	46899503	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.19573254605777463	[2]	[1,1]	-4	hSpCas9	positive selection	4280881
46900313	46900336	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.19098893025191563	[3]	[4,0]	-4	hSpCas9	positive selection	4280882
46899934	46899957	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.30348404319736544	[1]	[1,0]	6	hSpCas9	positive selection	4345139
46899901	46899924	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.15493499815446526	[2]	[2,0]	-3	hSpCas9	positive selection	4345140
46900336	46900359	11	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.18621947248489587	[3]	[3,2]	4	hSpCas9	positive selection	4345141
46883884	46883906	11	-	27760321	OCIAML3	viability	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	-0.14465699359648054	[725,573]	[426,495]	-1	hSpCas9	negative selection	4415149
46894772	46894794	11	-	27760321	OCIAML3	viability	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.5957389946796441	[958,814]	[878,1260]	7	hSpCas9	negative selection	4415150
46895185	46895207	11	-	27760321	OCIAML3	viability	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.5716050973694576	[825,708]	[370,443]	-5	hSpCas9	negative selection	4415151
46898945	46898967	11	-	27760321	OCIAML3	viability	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.11561559119208303	[638,579]	[440,613]	1	hSpCas9	negative selection	4415152
46899480	46899502	11	-	27760321	OCIAML3	viability	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.2895458833690448	[567,446]	[517,434]	3	hSpCas9	negative selection	4415153
46883884	46883906	11	-	27760321	OCIAML2	viability	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	-0.16311470832968383	[725,573]	[413,535]	-2	hSpCas9	negative selection	4498612
46894772	46894794	11	-	27760321	OCIAML2	viability	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	-0.20191684496924667	[958,814]	[515,760]	-3	hSpCas9	negative selection	4498613
46895185	46895207	11	-	27760321	OCIAML2	viability	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.22721324439882096	[825,708]	[407,687]	-3	hSpCas9	negative selection	4498614
46898945	46898967	11	-	27760321	OCIAML2	viability	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.31470244321534846	[638,579]	[393,398]	-4	hSpCas9	negative selection	4498615
46899480	46899502	11	-	27760321	OCIAML2	viability	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.16447070149170784	[567,446]	[416,509]	2	hSpCas9	negative selection	4498616
46883884	46883906	11	-	27760321	MV411	viability	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.7259761703282371	[725,573]	[208,1449]	5	hSpCas9	negative selection	4582075
46894772	46894794	11	-	27760321	MV411	viability	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	-0.7043991969410239	[958,814]	[120,713]	-5	hSpCas9	negative selection	4582076
46895185	46895207	11	-	27760321	MV411	viability	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.10382242262043806	[825,708]	[355,640]	0	hSpCas9	negative selection	4582077
46898945	46898967	11	-	27760321	MV411	viability	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.5099690898909264	[638,579]	[344,187]	-4	hSpCas9	negative selection	4582078
46899480	46899502	11	-	27760321	MV411	viability	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.5041033884585547	[567,446]	[236,230]	-4	hSpCas9	negative selection	4582079
46883884	46883906	11	-	27760321	HL60	viability	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	-0.6933259552059008	[725,573]	[335,315]	-6	hSpCas9	negative selection	4665538
46894772	46894794	11	-	27760321	HL60	viability	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.12563920758515046	[958,814]	[864,705]	1	hSpCas9	negative selection	4665539
46895185	46895207	11	-	27760321	HL60	viability	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.4168711790983282	[825,708]	[458,477]	-5	hSpCas9	negative selection	4665540
46898945	46898967	11	-	27760321	HL60	viability	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.7246990070111821	[638,579]	[286,315]	-6	hSpCas9	negative selection	4665541
46899480	46899502	11	-	27760321	HL60	viability	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.056856058255575354	[567,446]	[410,379]	0	hSpCas9	negative selection	4665542
46883884	46883906	11	-	27760321	HT1080	viability	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.6417145610824321	[573,447]	[245,395]	3	hSpCas9	negative selection	4749001
46894772	46894794	11	-	27760321	HT1080	viability	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.1841411625104128	[814,635]	[335,319]	0	hSpCas9	negative selection	4749002
46895185	46895207	11	-	27760321	HT1080	viability	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	1.3700851764570685	[708,552]	[601,701]	7	hSpCas9	negative selection	4749003
46898945	46898967	11	-	27760321	HT1080	viability	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-1.4796372334415973	[579,452]	[5,147]	-5	hSpCas9	negative selection	4749004
46899480	46899502	11	-	27760321	HT1080	viability	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	1.1454971537196779	[446,348]	[292,413]	6	hSpCas9	negative selection	4749005
46883884	46883906	11	-	27760321	HT29	viability after 7 days	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.22033191516082073	[573,447]	[973,621,729]	3	hSpCas9	negative selection	4832464
46894772	46894794	11	-	27760321	HT29	viability after 7 days	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.11917350836970408	[814,635]	[1480,751,875]	1	hSpCas9	negative selection	4832465
46895185	46895207	11	-	27760321	HT29	viability after 7 days	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.3830805286332954	[708,552]	[641,535,687]	-5	hSpCas9	negative selection	4832466
46898945	46898967	11	-	27760321	HT29	viability after 7 days	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.1567081647983894	[579,452]	[562,854,370]	-2	hSpCas9	negative selection	4832467
46899480	46899502	11	-	27760321	HT29	viability after 7 days	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.5403650274591959	[446,348]	[753,480,989]	7	hSpCas9	negative selection	4832468
46883884	46883906	11	-	27760321	HT29	viability after 25 days	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.40650322582595744	[573,447]	[717,767,845]	4	hSpCas9	negative selection	4915927
46894772	46894794	11	-	27760321	HT29	viability after 25 days	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.34677035975624104	[814,635]	[1091,1005,1061]	3	hSpCas9	negative selection	4915928
46895185	46895207	11	-	27760321	HT29	viability after 25 days	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.42024726554327285	[708,552]	[620,593,378]	-4	hSpCas9	negative selection	4915929
46898945	46898967	11	-	27760321	HT29	viability after 25 days	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.23216602625345384	[579,452]	[633,649,810]	2	hSpCas9	negative selection	4915930
46899480	46899502	11	-	27760321	HT29	viability after 25 days	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.5554030953009355	[446,348]	[599,512,921]	6	hSpCas9	negative selection	4915931
46883884	46883906	11	-	27760321	HT29	viability after 22 days	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.49579680767781664	[573,447]	[834,718,945]	5	hSpCas9	negative selection	4999390
46894772	46894794	11	-	27760321	HT29	viability after 22 days	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.3545543143162575	[814,635]	[895,1024,1302]	4	hSpCas9	negative selection	4999391
46895185	46895207	11	-	27760321	HT29	viability after 22 days	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.1398011112800147	[708,552]	[703,728,550]	-1	hSpCas9	negative selection	4999392
46898945	46898967	11	-	27760321	HT29	viability after 22 days	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.2590095966990231	[579,452]	[529,655,964]	2	hSpCas9	negative selection	4999393
46899480	46899502	11	-	27760321	HT29	viability after 22 days	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.5651697199099996	[446,348]	[794,584,658]	6	hSpCas9	negative selection	4999394
46883884	46883906	11	-	27760321	HT29	viability after 19 days	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.30121381994746643	[573,447]	[835,696,641]	3	hSpCas9	negative selection	5082853
46894772	46894794	11	-	27760321	HT29	viability after 19 days	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	-0.0022605556021733086	[814,635]	[937,911,652]	0	hSpCas9	negative selection	5082854
46895185	46895207	11	-	27760321	HT29	viability after 19 days	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.1896557266544031	[708,552]	[785,740,395]	-2	hSpCas9	negative selection	5082855
46898945	46898967	11	-	27760321	HT29	viability after 19 days	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.11905800112966364	[579,452]	[999,397,290]	-1	hSpCas9	negative selection	5082856
46899480	46899502	11	-	27760321	HT29	viability after 19 days	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.981156679130258	[446,348]	[1069,876,770]	8	hSpCas9	negative selection	5082857
46883884	46883906	11	-	27760321	HT29	viability after 16 days	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.6696289371881853	[573,447]	[721,960,1025]	7	hSpCas9	negative selection	5166316
46894772	46894794	11	-	27760321	HT29	viability after 16 days	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.27141503989641524	[814,635]	[1147,1164,636]	3	hSpCas9	negative selection	5166317
46895185	46895207	11	-	27760321	HT29	viability after 16 days	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.116935499989827	[708,552]	[814,624,528]	-1	hSpCas9	negative selection	5166318
46898945	46898967	11	-	27760321	HT29	viability after 16 days	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.04203197802695524	[579,452]	[616,552,617]	0	hSpCas9	negative selection	5166319
46899480	46899502	11	-	27760321	HT29	viability after 16 days	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.7394651657778585	[446,348]	[836,553,852]	8	hSpCas9	negative selection	5166320
46883884	46883906	11	-	27760321	HT29	viability after 13 days	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.47139911828536496	[573,447]	[955,716,793]	6	hSpCas9	negative selection	5249779
46894772	46894794	11	-	27760321	HT29	viability after 13 days	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.36045502860278256	[814,635]	[1256,1056,935]	4	hSpCas9	negative selection	5249780
46895185	46895207	11	-	27760321	HT29	viability after 13 days	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	0.4050256757380223	[708,552]	[1044,1039,830]	5	hSpCas9	negative selection	5249781
46898945	46898967	11	-	27760321	HT29	viability after 13 days	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.1523089689844681	[579,452]	[855,487,653]	1	hSpCas9	negative selection	5249782
46899480	46899502	11	-	27760321	HT29	viability after 13 days	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.35591628011069887	[446,348]	[524,659,587]	4	hSpCas9	negative selection	5249783
46883884	46883906	11	-	27760321	HT29	viability after 10 days	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	0.23889854032642632	[573,447]	[911,488,847]	3	hSpCas9	negative selection	5333242
46894772	46894794	11	-	27760321	HT29	viability after 10 days	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.17792462183984847	[814,635]	[885,926,1252]	2	hSpCas9	negative selection	5333243
46895185	46895207	11	-	27760321	HT29	viability after 10 days	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	-0.1626874039022549	[708,552]	[789,739,584]	-2	hSpCas9	negative selection	5333244
46898945	46898967	11	-	27760321	HT29	viability after 10 days	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.18349900982954515	[579,452]	[621,600,964]	2	hSpCas9	negative selection	5333245
46899480	46899502	11	-	27760321	HT29	viability after 10 days	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.529191864632653	[446,348]	[862,705,584]	7	hSpCas9	negative selection	5333246
46883884	46883906	11	-	27760321	MOLM13	viability	CGTCCTCGGGACATCGTGGTGG	LRP4	ENSG00000134569	-0.057317948689402876	[725,573]	[427,283]	0	hSpCas9	negative selection	5416705
46894772	46894794	11	-	27760321	MOLM13	viability	AATCGCATCGACATCCGGCAGG	LRP4	ENSG00000134569	0.25258158710915923	[958,814]	[732,475]	1	hSpCas9	negative selection	5416706
46895185	46895207	11	-	27760321	MOLM13	viability	CTATGAACTACGGCCCGACCGG	LRP4	ENSG00000134569	0.4478510744858044	[825,708]	[771,432]	3	hSpCas9	negative selection	5416707
46898945	46898967	11	-	27760321	MOLM13	viability	TCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.2818577927669545	[638,579]	[608,254]	2	hSpCas9	negative selection	5416708
46899480	46899502	11	-	27760321	MOLM13	viability	ATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.15632153596687398	[567,446]	[309,322]	1	hSpCas9	negative selection	5416709
46918465	46918488	11	+	27661255	K562	viability	GAAGCGTCCCGGGTGCACGGCGG	LRP4	ENSG00000134569	0.2144266114844916	[487,551]	[502,461]	7	dCas9-KRAB	negative selection	5490895
46918145	46918168	11	-	27661255	K562	viability	GGCTCCAGCAGTCCGAGCGGGGG	LRP4	ENSG00000134569	-0.12719304088147698	[143,140]	[120,89]	-4	dCas9-KRAB	negative selection	5490896
46918543	46918566	11	-	27661255	K562	viability	GTCCCCTGGCGGGGCAGCGTCGG	LRP4	ENSG00000134569	-0.06061276388532094	[555,545]	[446,400]	-2	dCas9-KRAB	negative selection	5490897
46899453	46899476	11	+	27260156	BXPC3	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.13344572560469808	[707]	[629,578,691,822]	-3	hSpCas9	negative selection	5553340
46899480	46899503	11	-	27260156	BXPC3	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.017494864251405673	[339]	[306,269,448,392]	0	hSpCas9	negative selection	5553341
46900313	46900336	11	-	27260156	BXPC3	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.06177602402778026	[712]	[809,593,977,729]	1	hSpCas9	negative selection	5553342
46899934	46899957	11	-	27260156	BXPC3	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.3913694143277908	[86]	[109,58,122,198]	8	hSpCas9	negative selection	5617599
46899901	46899924	11	-	27260156	BXPC3	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.21529525768220137	[246]	[196,249,238,200]	-5	hSpCas9	negative selection	5617600
46900336	46900359	11	-	27260156	BXPC3	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.08604709822169243	[776]	[628,679,918,862]	-2	hSpCas9	negative selection	5617601
46899453	46899476	11	+	27260156	A673	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.19550382407963796	[707]	[951,670,645,724]	-5	hSpCas9	negative selection	5674591
46899480	46899503	11	-	27260156	A673	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.19156612970627623	[339]	[389,309,347,387]	-5	hSpCas9	negative selection	5674592
46900313	46900336	11	-	27260156	A673	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.041925656563731595	[712]	[799,827,925,965]	1	hSpCas9	negative selection	5674593
46899934	46899957	11	-	27260156	A673	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.6603606362321672	[86]	[179,131,133,219]	9	hSpCas9	negative selection	5738850
46899901	46899924	11	-	27260156	A673	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.18810075492411893	[246]	[352,222,228,246]	-5	hSpCas9	negative selection	5738851
46900336	46900359	11	-	27260156	A673	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.16657778059364448	[776]	[892,816,820,797]	-4	hSpCas9	negative selection	5738852
46899453	46899476	11	+	27260156	A375	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.26237766103022436	[707]	[768,591,995,417]	-4	hSpCas9	negative selection	5795842
46899480	46899503	11	-	27260156	A375	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.30445321130135866	[339]	[307,429,332,238]	-4	hSpCas9	negative selection	5795843
46900313	46900336	11	-	27260156	A375	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.01929363826290542	[712]	[706,1134,798,778]	0	hSpCas9	negative selection	5795844
46899934	46899957	11	-	27260156	A375	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	1.2002127034737078	[86]	[187,420,99,247]	9	hSpCas9	negative selection	5860101
46899901	46899924	11	-	27260156	A375	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.6678655640255828	[246]	[207,222,131,169]	-7	hSpCas9	negative selection	5860102
46900336	46900359	11	-	27260156	A375	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.22661595455654215	[776]	[789,665,840,785]	-3	hSpCas9	negative selection	5860103
46899453	46899476	11	+	27260156	COLO741	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	0.2889053796821671	[707]	[1407,920,1015]	6	hSpCas9	negative selection	5917093
46899480	46899503	11	-	27260156	COLO741	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.29761504378208575	[339]	[477,527,585]	6	hSpCas9	negative selection	5917094
46900313	46900336	11	-	27260156	COLO741	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.1777027585897002	[712]	[1173,1079,859]	4	hSpCas9	negative selection	5917095
46899934	46899957	11	-	27260156	COLO741	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.5283906871237949	[86]	[129,213,135]	9	hSpCas9	negative selection	5981352
46899901	46899924	11	-	27260156	COLO741	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.2053422383806165	[246]	[348,220,257]	-4	hSpCas9	negative selection	5981353
46900336	46900359	11	-	27260156	COLO741	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.001561802297765258	[776]	[1007,915,1051]	0	hSpCas9	negative selection	5981354
46899453	46899476	11	+	27260156	CAL120	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.48457396263426056	[707]	[819,556,541]	-6	hSpCas9	negative selection	6038344
46899480	46899503	11	-	27260156	CAL120	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.6727527178196799	[339]	[295,254,249]	-7	hSpCas9	negative selection	6038345
46900313	46900336	11	-	27260156	CAL120	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.2767300218347548	[712]	[817,986,1374]	4	hSpCas9	negative selection	6038346
46899934	46899957	11	-	27260156	CAL120	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.5256691367358433	[86]	[165,89,211]	7	hSpCas9	negative selection	6102603
46899901	46899924	11	-	27260156	CAL120	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.1451340454636667	[246]	[602,133,147]	-2	hSpCas9	negative selection	6102604
46900336	46900359	11	-	27260156	CAL120	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.11510086825574162	[776]	[1154,930,635]	-2	hSpCas9	negative selection	6102605
46899453	46899476	11	+	27260156	CADOES1	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.4276188396119783	[707]	[539,488,443,484]	-6	hSpCas9	negative selection	6159595
46899480	46899503	11	-	27260156	CADOES1	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.40439895336428916	[339]	[294,177,202,280]	-6	hSpCas9	negative selection	6159596
46900313	46900336	11	-	27260156	CADOES1	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.11434245649543645	[712]	[542,642,591,674]	-2	hSpCas9	negative selection	6159597
46899934	46899957	11	-	27260156	CADOES1	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.9429402277101198	[86]	[186,199,85,148]	9	hSpCas9	negative selection	6223854
46899901	46899924	11	-	27260156	CADOES1	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.3315830676895879	[246]	[185,208,184,148]	-5	hSpCas9	negative selection	6223855
46900336	46900359	11	-	27260156	CADOES1	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.23734550042502883	[776]	[574,609,633,633]	-4	hSpCas9	negative selection	6223856
46899453	46899476	11	+	27260156	EWS502	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.2018575388889739	[707]	[700,655,547,695]	-4	hSpCas9	negative selection	6280846
46899480	46899503	11	-	27260156	EWS502	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.18534086043856873	[339]	[417,249,356,224]	-3	hSpCas9	negative selection	6280847
46900313	46900336	11	-	27260156	EWS502	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.07680735712415665	[712]	[836,798,601,947]	1	hSpCas9	negative selection	6280848
46899934	46899957	11	-	27260156	EWS502	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.7641890073358655	[86]	[138,145,144,200]	9	hSpCas9	negative selection	6345105
46899901	46899924	11	-	27260156	EWS502	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.4563609912266833	[246]	[199,182,252,120]	-6	hSpCas9	negative selection	6345106
46900336	46900359	11	-	27260156	EWS502	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.25972209623426856	[776]	[587,607,895,671]	-4	hSpCas9	negative selection	6345107
46899453	46899476	11	+	27260156	EW8	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.5210997156071489	[707]	[441,436,322,413]	-7	hSpCas9	negative selection	6402097
46899480	46899503	11	-	27260156	EW8	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.191252961670828	[339]	[250,249,209,259]	-4	hSpCas9	negative selection	6402098
46900313	46900336	11	-	27260156	EW8	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.2615848524311487	[712]	[624,1115,478,579]	5	hSpCas9	negative selection	6402099
46899934	46899957	11	-	27260156	EW8	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.6057481731233263	[86]	[77,136,87,125]	9	hSpCas9	negative selection	6466356
46899901	46899924	11	-	27260156	EW8	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.28400253786385643	[246]	[220,87,235,105]	-5	hSpCas9	negative selection	6466357
46900336	46900359	11	-	27260156	EW8	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.43184941309443653	[776]	[476,516,336,557]	-7	hSpCas9	negative selection	6466358
46899453	46899476	11	+	27260156	CORL105	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.5115534480280005	[707]	[653,530,593,551]	-7	hSpCas9	negative selection	6523348
46899480	46899503	11	-	27260156	CORL105	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.5933017597109715	[339]	[201,269,302,283]	-8	hSpCas9	negative selection	6523349
46900313	46900336	11	-	27260156	CORL105	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.24976569253825143	[712]	[910,977,1219,893]	4	hSpCas9	negative selection	6523350
46899934	46899957	11	-	27260156	CORL105	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.2896022427958447	[86]	[120,182,118,72]	5	hSpCas9	negative selection	6587607
46899901	46899924	11	-	27260156	CORL105	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.03740050870715328	[246]	[252,316,354,211]	0	hSpCas9	negative selection	6587608
46900336	46900359	11	-	27260156	CORL105	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.07564749547733063	[776]	[745,899,967,849]	-1	hSpCas9	negative selection	6587609
46899453	46899476	11	+	27260156	HS294T	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	0.0333100715950867	[707]	[341,228,310,223]	0	hSpCas9	negative selection	6644599
46899480	46899503	11	-	27260156	HS294T	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.3469759913304239	[339]	[199,162,155,141]	4	hSpCas9	negative selection	6644600
46900313	46900336	11	-	27260156	HS294T	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.40398382387056087	[712]	[281,416,355,417]	5	hSpCas9	negative selection	6644601
46899934	46899957	11	-	27260156	HS294T	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.1352011583998749	[86]	[21,20,22,92]	1	hSpCas9	negative selection	6708858
46899901	46899924	11	-	27260156	HS294T	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.02198203012586253	[246]	[37,104,78,171]	0	hSpCas9	negative selection	6708859
46900336	46900359	11	-	27260156	HS294T	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.22683615077508684	[776]	[144,293,302,300]	-3	hSpCas9	negative selection	6708860
46899453	46899476	11	+	27260156	HCC44	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.34557274356483647	[707]	[574,482,837,669]	-5	hSpCas9	negative selection	6765850
46899480	46899503	11	-	27260156	HCC44	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.07012989593327307	[339]	[370,404,447,250]	-1	hSpCas9	negative selection	6765851
46900313	46900336	11	-	27260156	HCC44	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.06392221060491488	[712]	[1069,714,762,841]	1	hSpCas9	negative selection	6765852
46899934	46899957	11	-	27260156	HCC44	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.43089301043470796	[86]	[94,94,162,181]	7	hSpCas9	negative selection	6830109
46899901	46899924	11	-	27260156	HCC44	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.04331991628232279	[246]	[304,167,202,470]	0	hSpCas9	negative selection	6830110
46900336	46900359	11	-	27260156	HCC44	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.38405743880811816	[776]	[615,537,790,773]	-5	hSpCas9	negative selection	6830111
46899453	46899476	11	+	27260156	G402	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.39221707012567064	[707]	[1001,743,511,437]	-5	hSpCas9	negative selection	6887101
46899480	46899503	11	-	27260156	G402	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.266553019437514	[339]	[264,474,411,227]	-3	hSpCas9	negative selection	6887102
46900313	46900336	11	-	27260156	G402	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.29610745897214386	[712]	[1127,1389,814,967]	3	hSpCas9	negative selection	6887103
46899934	46899957	11	-	27260156	G402	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	1.1657746428268485	[86]	[184,213,354,190]	9	hSpCas9	negative selection	6951360
46899901	46899924	11	-	27260156	G402	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.14128571340915008	[246]	[130,313,453,395]	1	hSpCas9	negative selection	6951361
46900336	46900359	11	-	27260156	G402	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.25467953300971635	[776]	[1736,1141,739,995]	3	hSpCas9	negative selection	6951362
46899453	46899476	11	+	27260156	L33	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.26140606235680236	[707]	[576,244,387,570]	-6	hSpCas9	negative selection	7008352
46899480	46899503	11	-	27260156	L33	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.36492867847114696	[339]	[412,155,288,497]	7	hSpCas9	negative selection	7008353
46900313	46900336	11	-	27260156	L33	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.1353136144276088	[712]	[892,295,417,847]	3	hSpCas9	negative selection	7008354
46899934	46899957	11	-	27260156	L33	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.8004026464066936	[86]	[112,67,111,149]	9	hSpCas9	negative selection	7072611
46899901	46899924	11	-	27260156	L33	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.31746291305311325	[246]	[249,79,108,172]	-6	hSpCas9	negative selection	7072612
46900336	46900359	11	-	27260156	L33	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.1755686544926338	[776]	[582,259,475,778]	-4	hSpCas9	negative selection	7072613
46899453	46899476	11	+	27260156	K562	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.8350787782084299	[707]	[458,265,357,330]	-7	hSpCas9	negative selection	7129603
46899480	46899503	11	-	27260156	K562	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.06006986381012075	[339]	[301,418,254,198]	0	hSpCas9	negative selection	7129604
46900313	46900336	11	-	27260156	K562	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.1191799615222694	[712]	[715,866,536,642]	1	hSpCas9	negative selection	7129605
46899934	46899957	11	-	27260156	K562	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	1.3974710407436188	[86]	[347,216,195,78]	9	hSpCas9	negative selection	7193862
46899901	46899924	11	-	27260156	K562	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.3206938922069038	[246]	[283,70,82,256]	-4	hSpCas9	negative selection	7193863
46900336	46900359	11	-	27260156	K562	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.33872240823925687	[776]	[576,472,728,413]	-4	hSpCas9	negative selection	7193864
46899453	46899476	11	+	27260156	HT29	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	0.11039478155579263	[707]	[994,1183,856,725]	2	hSpCas9	negative selection	7250854
46899480	46899503	11	-	27260156	HT29	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.29517271273878465	[339]	[689,453,406,485]	6	hSpCas9	negative selection	7250855
46900313	46900336	11	-	27260156	HT29	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.2769447768386619	[712]	[1005,1087,1184,928]	5	hSpCas9	negative selection	7250856
46899934	46899957	11	-	27260156	HT29	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.7051261676909168	[86]	[256,86,165,176]	9	hSpCas9	negative selection	7315113
46899901	46899924	11	-	27260156	HT29	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.1035511300463845	[246]	[428,322,215,175]	-2	hSpCas9	negative selection	7315114
46900336	46900359	11	-	27260156	HT29	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.08780184952078884	[776]	[1110,1092,889,937]	1	hSpCas9	negative selection	7315115
46899453	46899476	11	+	27260156	MHHES1	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.38383033493226626	[707]	[660,721,606,486]	-6	hSpCas9	negative selection	7372105
46899480	46899503	11	-	27260156	MHHES1	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-1.6623306852037167e-05	[339]	[406,366,422,337]	0	hSpCas9	negative selection	7372106
46900313	46900336	11	-	27260156	MHHES1	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.011537769337264248	[712]	[913,793,994,540]	0	hSpCas9	negative selection	7372107
46899934	46899957	11	-	27260156	MHHES1	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.32418089345419654	[86]	[208,74,120,94]	6	hSpCas9	negative selection	7436364
46899901	46899924	11	-	27260156	MHHES1	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.17526630175651503	[246]	[331,332,122,216]	-3	hSpCas9	negative selection	7436365
46900336	46900359	11	-	27260156	MHHES1	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.03217488801761148	[776]	[1131,653,807,953]	0	hSpCas9	negative selection	7436366
46899453	46899476	11	+	27260156	MEWO	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	0.15743308670772171	[707]	[680,717,805]	3	hSpCas9	negative selection	7493356
46899480	46899503	11	-	27260156	MEWO	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.029094446174991018	[339]	[345,281,349]	0	hSpCas9	negative selection	7493357
46900313	46900336	11	-	27260156	MEWO	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.06338485223716672	[712]	[720,640,568]	-1	hSpCas9	negative selection	7493358
46899934	46899957	11	-	27260156	MEWO	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.44390881800275306	[86]	[145,103,88]	8	hSpCas9	negative selection	7557615
46899901	46899924	11	-	27260156	MEWO	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.08059374868589175	[246]	[227,214,286]	1	hSpCas9	negative selection	7557616
46900336	46900359	11	-	27260156	MEWO	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.2719273244736335	[776]	[800,513,529]	-5	hSpCas9	negative selection	7557617
46899453	46899476	11	+	27260156	LNCAPCLONEFGC	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.07318603723261541	[707]	[572,761,523,556]	-1	hSpCas9	negative selection	7614607
46899480	46899503	11	-	27260156	LNCAPCLONEFGC	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.009204781488484803	[339]	[276,177,366,419]	0	hSpCas9	negative selection	7614608
46900313	46900336	11	-	27260156	LNCAPCLONEFGC	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.29175379524334544	[712]	[900,662,754,843]	4	hSpCas9	negative selection	7614609
46899934	46899957	11	-	27260156	LNCAPCLONEFGC	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.8460417904801021	[86]	[155,130,134,143]	9	hSpCas9	negative selection	7678866
46899901	46899924	11	-	27260156	LNCAPCLONEFGC	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.20396140043852307	[246]	[152,256,285,340]	3	hSpCas9	negative selection	7678867
46900336	46900359	11	-	27260156	LNCAPCLONEFGC	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.2844397397089954	[776]	[736,493,660,433]	-4	hSpCas9	negative selection	7678868
46899453	46899476	11	+	27260156	PANC0327	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.10451756632986026	[707]	[509,435,740,665]	-1	hSpCas9	negative selection	7735858
46899480	46899503	11	-	27260156	PANC0327	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.1316173426740045	[339]	[295,389,360,265]	2	hSpCas9	negative selection	7735859
46900313	46900336	11	-	27260156	PANC0327	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.08444958867117258	[712]	[560,544,618,667]	-1	hSpCas9	negative selection	7735860
46899934	46899957	11	-	27260156	PANC0327	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.5046197200689695	[86]	[83,113,164,72]	7	hSpCas9	negative selection	7800117
46899901	46899924	11	-	27260156	PANC0327	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.05227206806429019	[246]	[344,125,58,337]	-1	hSpCas9	negative selection	7800118
46900336	46900359	11	-	27260156	PANC0327	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.22200275999279728	[776]	[552,457,642,726]	-3	hSpCas9	negative selection	7800119
46899453	46899476	11	+	27260156	NCIH2009	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.38469622121349417	[707]	[913,679,709]	-5	hSpCas9	negative selection	7857109
46899480	46899503	11	-	27260156	NCIH2009	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.31317120611484023	[339]	[506,382,280]	-4	hSpCas9	negative selection	7857110
46900313	46900336	11	-	27260156	NCIH2009	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.41644739153632315	[712]	[1457,1148,1407]	6	hSpCas9	negative selection	7857111
46899934	46899957	11	-	27260156	NCIH2009	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.6377330572771129	[86]	[235,95,245]	8	hSpCas9	negative selection	7921368
46899901	46899924	11	-	27260156	NCIH2009	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.3597748350670913	[246]	[238,346,212]	-5	hSpCas9	negative selection	7921369
46900336	46900359	11	-	27260156	NCIH2009	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.31991078879722706	[776]	[881,980,744]	-4	hSpCas9	negative selection	7921370
46899453	46899476	11	+	27260156	NCIH1373	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.3988166208866887	[707]	[400,841,661,112]	-4	hSpCas9	negative selection	7978360
46899480	46899503	11	-	27260156	NCIH1373	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.05402084336512175	[339]	[501,266,412,81]	0	hSpCas9	negative selection	7978361
46900313	46900336	11	-	27260156	NCIH1373	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.27417191662418017	[712]	[1075,891,891,270]	2	hSpCas9	negative selection	7978362
46899934	46899957	11	-	27260156	NCIH1373	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.9420161403335066	[86]	[216,111,205,59]	8	hSpCas9	negative selection	8042619
46899901	46899924	11	-	27260156	NCIH1373	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.9958495402054717	[246]	[225,156,131,11]	-7	hSpCas9	negative selection	8042620
46900336	46900359	11	-	27260156	NCIH1373	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.6118592544695124	[776]	[542,419,568,201]	-6	hSpCas9	negative selection	8042621
46899453	46899476	11	+	27260156	PATU8902	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.9097168401671012	[707]	[543,613,308,705]	-7	hSpCas9	negative selection	8099611
46899480	46899503	11	-	27260156	PATU8902	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.5989727389409931	[339]	[575,298,188,198]	-5	hSpCas9	negative selection	8099612
46900313	46900336	11	-	27260156	PATU8902	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.02794654698391319	[712]	[1159,745,843,1375]	0	hSpCas9	negative selection	8099613
46899934	46899957	11	-	27260156	PATU8902	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.891141342663466	[86]	[421,24,190,269]	8	hSpCas9	negative selection	8163870
46899901	46899924	11	-	27260156	PATU8902	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.25321326740138494	[246]	[157,219,201,637]	-3	hSpCas9	negative selection	8163871
46900336	46900359	11	-	27260156	PATU8902	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.16498451988888807	[776]	[649,948,808,1560]	-2	hSpCas9	negative selection	8163872
46899453	46899476	11	+	27260156	PANC1	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	0.16049015827570223	[707]	[533,671,896,617]	2	hSpCas9	negative selection	8220862
46899480	46899503	11	-	27260156	PANC1	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.08074567059441029	[339]	[283,298,198,425]	1	hSpCas9	negative selection	8220863
46900313	46900336	11	-	27260156	PANC1	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.3138214273461626	[712]	[834,840,842,561]	5	hSpCas9	negative selection	8220864
46899934	46899957	11	-	27260156	PANC1	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.7440048827543722	[86]	[181,94,129,89]	9	hSpCas9	negative selection	8285121
46899901	46899924	11	-	27260156	PANC1	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.3885658872660507	[246]	[393,346,266,133]	6	hSpCas9	negative selection	8285122
46900336	46900359	11	-	27260156	PANC1	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.23215379972107197	[776]	[604,954,951,669]	3	hSpCas9	negative selection	8285123
46899453	46899476	11	+	27260156	PANC0813	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.13820389098221192	[707]	[1096,563,883,521]	-2	hSpCas9	negative selection	8342113
46899480	46899503	11	-	27260156	PANC0813	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.0507185720820576	[339]	[371,410,382,374]	-1	hSpCas9	negative selection	8342114
46900313	46900336	11	-	27260156	PANC0813	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.20778964653148257	[712]	[901,1207,1136,633]	3	hSpCas9	negative selection	8342115
46899934	46899957	11	-	27260156	PANC0813	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.5572527288799991	[86]	[125,106,192,171]	8	hSpCas9	negative selection	8406372
46899901	46899924	11	-	27260156	PANC0813	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.01841880895917669	[246]	[263,372,186,316]	0	hSpCas9	negative selection	8406373
46900336	46900359	11	-	27260156	PANC0813	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.42024316741514844	[776]	[963,641,581,570]	-6	hSpCas9	negative selection	8406374
46899453	46899476	11	+	27260156	RDES	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.8230202584757051	[707]	[381,371,488,637]	-8	hSpCas9	negative selection	8463364
46899480	46899503	11	-	27260156	RDES	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.5268364105798262	[339]	[234,220,325,316]	-7	hSpCas9	negative selection	8463365
46900313	46900336	11	-	27260156	RDES	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.06428320899554096	[712]	[698,705,952,1141]	1	hSpCas9	negative selection	8463366
46899934	46899957	11	-	27260156	RDES	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.8285726859163063	[86]	[111,253,196,144]	9	hSpCas9	negative selection	8527623
46899901	46899924	11	-	27260156	RDES	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.5468998476894484	[246]	[131,146,230,297]	-7	hSpCas9	negative selection	8527624
46900336	46900359	11	-	27260156	RDES	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.5704505375760054	[776]	[480,580,639,736]	-7	hSpCas9	negative selection	8527625
46899453	46899476	11	+	27260156	PC3	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.09959699651914722	[707]	[578,689,681,635]	-2	hSpCas9	negative selection	8584615
46899480	46899503	11	-	27260156	PC3	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.010290521179782242	[339]	[273,259,452,417]	0	hSpCas9	negative selection	8584616
46900313	46900336	11	-	27260156	PC3	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.19758174804592343	[712]	[551,858,1017,941]	4	hSpCas9	negative selection	8584617
46899934	46899957	11	-	27260156	PC3	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.6954118337319377	[86]	[116,84,263,139]	9	hSpCas9	negative selection	8648874
46899901	46899924	11	-	27260156	PC3	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.2612240447289669	[246]	[151,155,420,178]	-5	hSpCas9	negative selection	8648875
46900336	46900359	11	-	27260156	PC3	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.1807553986111815	[776]	[371,822,1148,636]	-4	hSpCas9	negative selection	8648876
46899453	46899476	11	+	27260156	PATU8988T	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.05554083358902595	[707]	[570,671,666,729]	-1	hSpCas9	negative selection	8705866
46899480	46899503	11	-	27260156	PATU8988T	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.38686869289990367	[339]	[689,429,268,322]	6	hSpCas9	negative selection	8705867
46900313	46900336	11	-	27260156	PATU8988T	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.054365892322286835	[712]	[744,748,729,633]	0	hSpCas9	negative selection	8705868
46899934	46899957	11	-	27260156	PATU8988T	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.3279198499812863	[86]	[101,83,154,75]	5	hSpCas9	negative selection	8770125
46899901	46899924	11	-	27260156	PATU8988T	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.31564128215231113	[246]	[526,269,254,119]	5	hSpCas9	negative selection	8770126
46900336	46900359	11	-	27260156	PATU8988T	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.185328423502233	[776]	[630,788,728,1296]	3	hSpCas9	negative selection	8770127
46899453	46899476	11	+	27260156	T47D	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.48735224306583547	[707]	[591,522,652,589]	-7	hSpCas9	negative selection	8827117
46899480	46899503	11	-	27260156	T47D	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.43647193920773425	[339]	[260,270,337,301]	-7	hSpCas9	negative selection	8827118
46900313	46900336	11	-	27260156	T47D	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.026654826129083764	[712]	[852,732,865,815]	0	hSpCas9	negative selection	8827119
46899934	46899957	11	-	27260156	T47D	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.2671498898411495	[86]	[118,92,131,146]	5	hSpCas9	negative selection	8891376
46899901	46899924	11	-	27260156	T47D	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.2614788603638418	[246]	[296,224,246,190]	-5	hSpCas9	negative selection	8891377
46900336	46900359	11	-	27260156	T47D	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.12295156028727505	[776]	[722,804,932,864]	-3	hSpCas9	negative selection	8891378
46899453	46899476	11	+	27260156	SU8686	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.2584158476935941	[707]	[516,457,699,716]	-4	hSpCas9	negative selection	8948368
46899480	46899503	11	-	27260156	SU8686	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.24511069799573654	[339]	[208,270,369,300]	-4	hSpCas9	negative selection	8948369
46900313	46900336	11	-	27260156	SU8686	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.07862214353820662	[712]	[630,821,820,704]	1	hSpCas9	negative selection	8948370
46899934	46899957	11	-	27260156	SU8686	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.8154930317966707	[86]	[70,181,157,209]	9	hSpCas9	negative selection	9012627
46899901	46899924	11	-	27260156	SU8686	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.2584818354362024	[246]	[273,157,194,184]	-4	hSpCas9	negative selection	9012628
46900336	46900359	11	-	27260156	SU8686	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.2881825947040617	[776]	[543,507,689,837]	-5	hSpCas9	negative selection	9012629
46899453	46899476	11	+	27260156	SKES1	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.11597473346276771	[707]	[698,687,761,480]	-3	hSpCas9	negative selection	9069619
46899480	46899503	11	-	27260156	SKES1	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	0.18483613962625045	[339]	[400,434,440,280]	4	hSpCas9	negative selection	9069620
46900313	46900336	11	-	27260156	SKES1	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.12813403716054228	[712]	[822,742,953,601]	3	hSpCas9	negative selection	9069621
46899934	46899957	11	-	27260156	SKES1	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.8325199145642297	[86]	[145,80,134,234]	9	hSpCas9	negative selection	9133878
46899901	46899924	11	-	27260156	SKES1	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.14978910619068286	[246]	[161,274,276,174]	-3	hSpCas9	negative selection	9133879
46900336	46900359	11	-	27260156	SKES1	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.06222960618798057	[776]	[846,816,713,621]	-1	hSpCas9	negative selection	9133880
46899453	46899476	11	+	27260156	TOV112D	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.35027799805588244	[707]	[475,821,439,544]	-6	hSpCas9	negative selection	9190870
46899480	46899503	11	-	27260156	TOV112D	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.27191634610553744	[339]	[246,276,227,368]	-5	hSpCas9	negative selection	9190871
46900313	46900336	11	-	27260156	TOV112D	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.2569761813181918	[712]	[930,1420,672,541]	5	hSpCas9	negative selection	9190872
46899934	46899957	11	-	27260156	TOV112D	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.07386243244748414	[86]	[74,233,60,31]	1	hSpCas9	negative selection	9255129
46899901	46899924	11	-	27260156	TOV112D	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.2998157880802923	[246]	[287,319,170,64]	-5	hSpCas9	negative selection	9255130
46900336	46900359	11	-	27260156	TOV112D	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.2555867883249142	[776]	[673,1127,401,524]	-5	hSpCas9	negative selection	9255131
46899453	46899476	11	+	27260156	TC71	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.1769341566930384	[707]	[743,613,646,679]	-5	hSpCas9	negative selection	9312121
46899480	46899503	11	-	27260156	TC71	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.056201198533492536	[339]	[410,303,357,325]	-1	hSpCas9	negative selection	9312122
46900313	46900336	11	-	27260156	TC71	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	-0.06832217872257229	[712]	[830,640,622,827]	-2	hSpCas9	negative selection	9312123
46899934	46899957	11	-	27260156	TC71	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	1.2591028834332458	[86]	[213,185,243,249]	9	hSpCas9	negative selection	9376380
46899901	46899924	11	-	27260156	TC71	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	-0.035140945972413795	[246]	[272,252,184,328]	-1	hSpCas9	negative selection	9376381
46900336	46900359	11	-	27260156	TC71	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	0.030532452269019572	[776]	[961,840,725,876]	0	hSpCas9	negative selection	9376382
46899453	46899476	11	+	27260156	TC32	viability	TGCAGCTTCCGTCACTACAGCGG	LRP4	ENSG00000134569	-0.13683907114394173	[707]	[580,552,877,429]	-2	hSpCas9	negative selection	9433372
46899480	46899503	11	-	27260156	TC32	viability	CATGCGCAAGTGCTCCGACAAGG	LRP4	ENSG00000134569	-0.636470638338581	[339]	[243,108,216,277]	-8	hSpCas9	negative selection	9433373
46900313	46900336	11	-	27260156	TC32	viability	CAAGTGCATCCGCCGCTCCTGGG	LRP4	ENSG00000134569	0.15651630543993644	[712]	[751,410,1139,842]	3	hSpCas9	negative selection	9433374
46899934	46899957	11	-	27260156	TC32	viability	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.5857637335012447	[86]	[116,46,128,227]	8	hSpCas9	negative selection	9497631
46899901	46899924	11	-	27260156	TC32	viability	CGGAGTCTGTGGCACTGCGATGG	LRP4	ENSG00000134569	0.036900878532366455	[246]	[281,223,211,211]	0	hSpCas9	negative selection	9497632
46900336	46900359	11	-	27260156	TC32	viability	CTTGACTTTCACTGTGACAATGG	LRP4	ENSG00000134569	-0.2537074214014039	[776]	[665,463,761,593]	-4	hSpCas9	negative selection	9497633
46898945	46898968	11	-	27869803	HPAFII	viability after 27 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.0851097984500705	[378]	[338,104,NaN]	0	hSpCas9	negative selection	9541674
46899407	46899430	11	-	27869803	HPAFII	viability after 27 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.3001346223330338	[223]	[156,134,NaN]	2	hSpCas9	negative selection	9541675
46899934	46899957	11	-	27869803	HPAFII	viability after 27 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.012697068013654333	[180]	[71,115,NaN]	0	hSpCas9	negative selection	9541676
46900301	46900324	11	-	27869803	HPAFII	viability after 27 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.6592840835898274	[620]	[287,138,NaN]	-5	hSpCas9	negative selection	9541677
46902825	46902848	11	+	27869803	HPAFII	viability after 27 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.37458939808503366	[88]	[34,36,NaN]	-3	hSpCas9	negative selection	9541678
46918323	46918346	11	+	27869803	HPAFII	viability after 27 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.08215290743288661	[458]	[321,199,NaN]	0	hSpCas9	negative selection	9541679
46898945	46898968	11	-	27869803	HPAFII	viability after 15 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.2510806296084642	[378]	[443,278,NaN]	-3	hSpCas9	negative selection	9624123
46899407	46899430	11	-	27869803	HPAFII	viability after 15 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.10214340172840852	[223]	[235,216,NaN]	-1	hSpCas9	negative selection	9624124
46899934	46899957	11	-	27869803	HPAFII	viability after 15 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.15309560933287136	[180]	[256,190,NaN]	1	hSpCas9	negative selection	9624125
46900301	46900324	11	-	27869803	HPAFII	viability after 15 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.19404725083155627	[620]	[1212,483,NaN]	2	hSpCas9	negative selection	9624126
46902825	46902848	11	+	27869803	HPAFII	viability after 15 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	0.11237480020457546	[88]	[95,107,NaN]	1	hSpCas9	negative selection	9624127
46918323	46918346	11	+	27869803	HPAFII	viability after 15 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-0.2881762381514432	[458]	[567,301,NaN]	-3	hSpCas9	negative selection	9624128
46898945	46898968	11	-	27869803	ASPC1	viability after 36 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.44143952455040875	[1151]	[179,394,295]	-4	hSpCas9	negative selection	9706572
46899407	46899430	11	-	27869803	ASPC1	viability after 36 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.10550954120478237	[526]	[311,96,128]	-1	hSpCas9	negative selection	9706573
46899934	46899957	11	-	27869803	ASPC1	viability after 36 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.4125738701677229	[459]	[430,107,142]	4	hSpCas9	negative selection	9706574
46900301	46900324	11	-	27869803	ASPC1	viability after 36 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.18961272498838366	[1511]	[731,454,620]	1	hSpCas9	negative selection	9706575
46902825	46902848	11	+	27869803	ASPC1	viability after 36 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.2297977442670991	[250]	[43,0,153]	-2	hSpCas9	negative selection	9706576
46918323	46918346	11	+	27869803	ASPC1	viability after 36 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.5852178596488208	[942]	[942,258,359]	6	hSpCas9	negative selection	9706577
46898945	46898968	11	-	27869803	PATU8988S	viability after 35 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.1287934204633725	[1000]	[465,270,NaN]	-1	hSpCas9	negative selection	9789021
46899407	46899430	11	-	27869803	PATU8988S	viability after 35 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.626123378734089	[290]	[131,229,NaN]	7	hSpCas9	negative selection	9789022
46899934	46899957	11	-	27869803	PATU8988S	viability after 35 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.018885512923699443	[503]	[132,267,NaN]	0	hSpCas9	negative selection	9789023
46900301	46900324	11	-	27869803	PATU8988S	viability after 35 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.1850158667723314	[1497]	[400,660,NaN]	-2	hSpCas9	negative selection	9789024
46902825	46902848	11	+	27869803	PATU8988S	viability after 35 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.19735011217177356	[221]	[68,86,NaN]	-2	hSpCas9	negative selection	9789025
46918323	46918346	11	+	27869803	PATU8988S	viability after 35 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.4000420030019219	[693]	[291,445,NaN]	4	hSpCas9	negative selection	9789026
46898945	46898968	11	-	27869803	PATU8988S	viability after 31 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	-0.2968759203889151	[1000]	[261,404,NaN]	-3	hSpCas9	negative selection	9871470
46899407	46899430	11	-	27869803	PATU8988S	viability after 31 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.7134777499342533	[290]	[129,266,NaN]	8	hSpCas9	negative selection	9871471
46899934	46899957	11	-	27869803	PATU8988S	viability after 31 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	0.34756342473526514	[503]	[216,304,NaN]	4	hSpCas9	negative selection	9871472
46900301	46900324	11	-	27869803	PATU8988S	viability after 31 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.36823549201907624	[1497]	[460,464,NaN]	-4	hSpCas9	negative selection	9871473
46902825	46902848	11	+	27869803	PATU8988S	viability after 31 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.1773550927731431	[221]	[83,70,NaN]	-2	hSpCas9	negative selection	9871474
46918323	46918346	11	+	27869803	PATU8988S	viability after 31 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	0.49418336987416384	[693]	[281,526,NaN]	6	hSpCas9	negative selection	9871475
46898945	46898968	11	-	27869803	HPAFII	viability after 35 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.39769767878763496	[378]	[256,247,NaN]	2	hSpCas9	negative selection	9953919
46899407	46899430	11	-	27869803	HPAFII	viability after 35 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	-0.02336954135491809	[223]	[88,136,NaN]	0	hSpCas9	negative selection	9953920
46899934	46899957	11	-	27869803	HPAFII	viability after 35 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.6398579264420178	[180]	[23,97,NaN]	-4	hSpCas9	negative selection	9953921
46900301	46900324	11	-	27869803	HPAFII	viability after 35 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	0.20214541010077136	[620]	[395,322,NaN]	1	hSpCas9	negative selection	9953922
46902825	46902848	11	+	27869803	HPAFII	viability after 35 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.8431890779505402	[88]	[18,31,NaN]	-5	hSpCas9	negative selection	9953923
46918323	46918346	11	+	27869803	HPAFII	viability after 35 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-0.17210133932498906	[458]	[209,201,NaN]	-1	hSpCas9	negative selection	9953924
46898945	46898968	11	-	27869803	HPAFII	viability after 31 days	CTCGACATCTACCACTGCGATGG	LRP4	ENSG00000134569	0.2634072525978466	[378]	[250,259,NaN]	1	hSpCas9	negative selection	10036368
46899407	46899430	11	-	27869803	HPAFII	viability after 31 days	GGTGACACCGACTGCAAAGATGG	LRP4	ENSG00000134569	0.10854552586287816	[223]	[113,158,NaN]	0	hSpCas9	negative selection	10036369
46899934	46899957	11	-	27869803	HPAFII	viability after 31 days	GACGAGTTTCCCTGCCAGAATGG	LRP4	ENSG00000134569	-0.3792240441533308	[180]	[57,99,NaN]	-3	hSpCas9	negative selection	10036370
46900301	46900324	11	-	27869803	HPAFII	viability after 31 days	CCGCTCCTGGGTGTGTGACGGGG	LRP4	ENSG00000134569	-0.09035661022851538	[620]	[312,342,NaN]	0	hSpCas9	negative selection	10036371
46902825	46902848	11	+	27869803	HPAFII	viability after 31 days	CATCACACTGCCACTGGGCAGGG	LRP4	ENSG00000134569	-0.415743609907689	[88]	[24,50,NaN]	-3	hSpCas9	negative selection	10036372
46918323	46918346	11	+	27869803	HPAFII	viability after 31 days	CTTACCGTGTGCGCAGAGCAGGG	LRP4	ENSG00000134569	-0.09955746591812809	[458]	[260,217,NaN]	0	hSpCas9	negative selection	10036373
46900304	46900327	11	+	28162770	P31FUJ	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.22176365905110254	[188]	[258]	2	hSpCas9	negative selection	10185833
46890276	46890299	11	-	28162770	P31FUJ	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-0.05222995877255793	[164]	[186]	0	hSpCas9	negative selection	10185834
46899428	46899451	11	-	28162770	P31FUJ	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.11678223337584925	[123]	[157]	1	hSpCas9	negative selection	10185835
46896914	46896937	11	-	28162770	P31FUJ	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.29475798526185554	[187]	[270]	3	hSpCas9	negative selection	10185836
46896260	46896283	11	-	28162770	P31FUJ	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.6964584089134013	[170]	[123]	-5	hSpCas9	negative selection	10185837
46895234	46895257	11	-	28162770	P31FUJ	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	-0.18504907296601045	[207]	[214]	-2	hSpCas9	negative selection	10185838
46894616	46894639	11	-	28162770	P31FUJ	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.046790218804429795	[326]	[371]	0	hSpCas9	negative selection	10185839
46893068	46893091	11	-	28162770	P31FUJ	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.7420443183572832	[404]	[795]	8	hSpCas9	negative selection	10185840
46893019	46893042	11	+	28162770	P31FUJ	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.8165638729066012	[157]	[326]	8	hSpCas9	negative selection	10185841
46892998	46893021	11	-	28162770	P31FUJ	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.9002268653275078	[269]	[84]	-8	hSpCas9	negative selection	10185842
46900304	46900327	11	+	28162770	TF1	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	NaN	[NaN]	[112]	1	hSpCas9	negative selection	10355199
46890276	46890299	11	-	28162770	TF1	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	NaN	[NaN]	[165]	1	hSpCas9	negative selection	10355200
46899428	46899451	11	-	28162770	TF1	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	NaN	[NaN]	[160]	1	hSpCas9	negative selection	10355201
46896914	46896937	11	-	28162770	TF1	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	NaN	[NaN]	[169]	1	hSpCas9	negative selection	10355202
46896260	46896283	11	-	28162770	TF1	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	NaN	[NaN]	[153]	1	hSpCas9	negative selection	10355203
46895234	46895257	11	-	28162770	TF1	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	NaN	[NaN]	[185]	1	hSpCas9	negative selection	10355204
46894616	46894639	11	-	28162770	TF1	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	NaN	[NaN]	[247]	1	hSpCas9	negative selection	10355205
46893068	46893091	11	-	28162770	TF1	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	NaN	[NaN]	[353]	1	hSpCas9	negative selection	10355206
46893019	46893042	11	+	28162770	TF1	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	NaN	[NaN]	[352]	1	hSpCas9	negative selection	10355207
46892998	46893021	11	-	28162770	TF1	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	NaN	[NaN]	[60]	1	hSpCas9	negative selection	10355208
46900304	46900327	11	+	28162770	SKM1	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.39617847202752804	[48]	[113]	4	hSpCas9	negative selection	10524565
46890276	46890299	11	-	28162770	SKM1	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	0.5219527031953558	[38]	[98]	5	hSpCas9	negative selection	10524566
46899428	46899451	11	-	28162770	SKM1	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	-0.07575829026778846	[30]	[51]	0	hSpCas9	negative selection	10524567
46896914	46896937	11	-	28162770	SKM1	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.302694049427309	[71]	[156]	3	hSpCas9	negative selection	10524568
46896260	46896283	11	-	28162770	SKM1	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.26946067499322685	[59]	[87]	-2	hSpCas9	negative selection	10524569
46895234	46895257	11	-	28162770	SKM1	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	1.8073549220576042	[47]	[296]	9	hSpCas9	negative selection	10524570
46894616	46894639	11	-	28162770	SKM1	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	0.4768427837523157	[62]	[154]	4	hSpCas9	negative selection	10524571
46893068	46893091	11	-	28162770	SKM1	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.14627373337766697	[76]	[122]	-1	hSpCas9	negative selection	10524572
46893019	46893042	11	+	28162770	SKM1	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.14557682428561688	[44]	[87]	1	hSpCas9	negative selection	10524573
46892998	46893021	11	-	28162770	SKM1	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.687072117935897	[50]	[27]	-8	hSpCas9	negative selection	10524574
46900304	46900327	11	+	28162770	SKM1	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.39617847202752804	[48]	[113]	4	hSpCas9	negative selection	10693931
46890276	46890299	11	-	28162770	SKM1	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	0.5219527031953558	[38]	[98]	5	hSpCas9	negative selection	10693932
46899428	46899451	11	-	28162770	SKM1	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	-0.07575829026778846	[30]	[51]	0	hSpCas9	negative selection	10693933
46896914	46896937	11	-	28162770	SKM1	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.302694049427309	[71]	[156]	3	hSpCas9	negative selection	10693934
46896260	46896283	11	-	28162770	SKM1	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.26946067499322685	[59]	[87]	-2	hSpCas9	negative selection	10693935
46895234	46895257	11	-	28162770	SKM1	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	1.8073549220576042	[47]	[296]	9	hSpCas9	negative selection	10693936
46894616	46894639	11	-	28162770	SKM1	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	0.4768427837523157	[62]	[154]	4	hSpCas9	negative selection	10693937
46893068	46893091	11	-	28162770	SKM1	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.14627373337766697	[76]	[122]	-1	hSpCas9	negative selection	10693938
46893019	46893042	11	+	28162770	SKM1	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.14557682428561688	[44]	[87]	1	hSpCas9	negative selection	10693939
46892998	46893021	11	-	28162770	SKM1	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.687072117935897	[50]	[27]	-8	hSpCas9	negative selection	10693940
46900304	46900327	11	+	28162770	PL21	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	1.056093244872613	[220]	[199]	8	hSpCas9	negative selection	10863297
46890276	46890299	11	-	28162770	PL21	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-1.0311859316171352	[107]	[22]	-6	hSpCas9	negative selection	10863298
46899428	46899451	11	-	28162770	PL21	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.8201085650383896	[94]	[72]	7	hSpCas9	negative selection	10863299
46896914	46896937	11	-	28162770	PL21	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.039674942296074066	[189]	[84]	0	hSpCas9	negative selection	10863300
46896260	46896283	11	-	28162770	PL21	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	0.03186813189952131	[217]	[96]	0	hSpCas9	negative selection	10863301
46895234	46895257	11	-	28162770	PL21	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.3339953612241107	[143]	[78]	3	hSpCas9	negative selection	10863302
46894616	46894639	11	-	28162770	PL21	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.22516622024335076	[187]	[69]	-2	hSpCas9	negative selection	10863303
46893068	46893091	11	-	28162770	PL21	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.8891410797602168	[262]	[211]	7	hSpCas9	negative selection	10863304
46893019	46893042	11	+	28162770	PL21	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	1.9100603856412977	[139]	[228]	9	hSpCas9	negative selection	10863305
46892998	46893021	11	-	28162770	PL21	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-0.6743295034268211	[197]	[53]	-5	hSpCas9	negative selection	10863306
46900304	46900327	11	+	28162770	P31FUJ	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.22176365905110254	[188]	[258]	2	hSpCas9	negative selection	11032663
46890276	46890299	11	-	28162770	P31FUJ	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-0.05222995877255793	[164]	[186]	0	hSpCas9	negative selection	11032664
46899428	46899451	11	-	28162770	P31FUJ	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.11678223337584925	[123]	[157]	1	hSpCas9	negative selection	11032665
46896914	46896937	11	-	28162770	P31FUJ	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.29475798526185554	[187]	[270]	3	hSpCas9	negative selection	11032666
46896260	46896283	11	-	28162770	P31FUJ	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.6964584089134013	[170]	[123]	-5	hSpCas9	negative selection	11032667
46895234	46895257	11	-	28162770	P31FUJ	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	-0.18504907296601045	[207]	[214]	-2	hSpCas9	negative selection	11032668
46894616	46894639	11	-	28162770	P31FUJ	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.046790218804429795	[326]	[371]	0	hSpCas9	negative selection	11032669
46893068	46893091	11	-	28162770	P31FUJ	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.7420443183572832	[404]	[795]	8	hSpCas9	negative selection	11032670
46893019	46893042	11	+	28162770	P31FUJ	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.8165638729066012	[157]	[326]	8	hSpCas9	negative selection	11032671
46892998	46893021	11	-	28162770	P31FUJ	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.9002268653275078	[269]	[84]	-8	hSpCas9	negative selection	11032672
46900304	46900327	11	+	28162770	OCIAML5	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	-0.41215440294612377	[114]	[155]	-3	hSpCas9	negative selection	11202029
46890276	46890299	11	-	28162770	OCIAML5	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	0.6231323636316168	[90]	[252]	5	hSpCas9	negative selection	11202030
46899428	46899451	11	-	28162770	OCIAML5	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.24104283352748457	[44]	[95]	2	hSpCas9	negative selection	11202031
46896914	46896937	11	-	28162770	OCIAML5	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	1.2724154598171484	[85]	[374]	9	hSpCas9	negative selection	11202032
46896260	46896283	11	-	28162770	OCIAML5	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-1.0125312430572428	[75]	[67]	-6	hSpCas9	negative selection	11202033
46895234	46895257	11	-	28162770	OCIAML5	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.9552883511936072	[91]	[321]	8	hSpCas9	negative selection	11202034
46894616	46894639	11	-	28162770	OCIAML5	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	0.6516998470091783	[133]	[379]	6	hSpCas9	negative selection	11202035
46893068	46893091	11	-	28162770	OCIAML5	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.20950870825695644	[171]	[358]	1	hSpCas9	negative selection	11202036
46893019	46893042	11	+	28162770	OCIAML5	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	-0.2572225586288767	[193]	[292]	-2	hSpCas9	negative selection	11202037
46892998	46893021	11	-	28162770	OCIAML5	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.201400823092011	[92]	[72]	-6	hSpCas9	negative selection	11202038
46900304	46900327	11	+	28162770	EOL1	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.1537938639480449	[359]	[210]	1	hSpCas9	negative selection	11371395
46890276	46890299	11	-	28162770	EOL1	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-0.555061729004393	[197]	[70]	-4	hSpCas9	negative selection	11371396
46899428	46899451	11	-	28162770	EOL1	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	-0.8517802548664452	[160]	[46]	-5	hSpCas9	negative selection	11371397
46896914	46896937	11	-	28162770	EOL1	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.5614380643355517	[381]	[296]	5	hSpCas9	negative selection	11371398
46896260	46896283	11	-	28162770	EOL1	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-1.7758919465705578	[324]	[49]	-8	hSpCas9	negative selection	11371399
46895234	46895257	11	-	28162770	EOL1	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.49712654783585836	[389]	[289]	4	hSpCas9	negative selection	11371400
46894616	46894639	11	-	28162770	EOL1	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	0.07541443719716232	[253]	[140]	0	hSpCas9	negative selection	11371401
46893068	46893091	11	-	28162770	EOL1	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.17594747692092522	[414]	[246]	1	hSpCas9	negative selection	11371402
46893019	46893042	11	+	28162770	EOL1	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.2004634687010608	[222]	[134]	1	hSpCas9	negative selection	11371403
46892998	46893021	11	-	28162770	EOL1	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-0.6871816387134071	[271]	[88]	-5	hSpCas9	negative selection	11371404
46900304	46900327	11	+	28162770	MOLM13	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.2675907310587476	[269]	[234]	2	hSpCas9	negative selection	11540761
46890276	46890299	11	-	28162770	MOLM13	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-0.8253069947994675	[173]	[70]	-4	hSpCas9	negative selection	11540762
46899428	46899451	11	-	28162770	MOLM13	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.3809537447732981	[170]	[160]	2	hSpCas9	negative selection	11540763
46896914	46896937	11	-	28162770	MOLM13	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.9700254511361144	[232]	[329]	7	hSpCas9	negative selection	11540764
46896260	46896283	11	-	28162770	MOLM13	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-1.721144442845438	[227]	[49]	-7	hSpCas9	negative selection	11540765
46895234	46895257	11	-	28162770	MOLM13	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	1.5005780002507534	[239]	[490]	9	hSpCas9	negative selection	11540766
46894616	46894639	11	-	28162770	MOLM13	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-1.180498499318211	[278]	[88]	-6	hSpCas9	negative selection	11540767
46893068	46893091	11	-	28162770	MOLM13	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.007621976760580185	[405]	[291]	0	hSpCas9	negative selection	11540768
46893019	46893042	11	+	28162770	MOLM13	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.6104284951918122	[259]	[286]	4	hSpCas9	negative selection	11540769
46892998	46893021	11	-	28162770	MOLM13	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.6535741309410883	[160]	[36]	-7	hSpCas9	negative selection	11540770
46900304	46900327	11	+	28162770	HEL	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	-0.634599111862935	[222]	[91]	-4	hSpCas9	negative selection	11710127
46890276	46890299	11	-	28162770	HEL	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	0.14753098403752984	[147]	[104]	1	hSpCas9	negative selection	11710128
46899428	46899451	11	-	28162770	HEL	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	-0.3771607254373479	[145]	[71]	-3	hSpCas9	negative selection	11710129
46896914	46896937	11	-	28162770	HEL	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.7122239323216408	[303]	[318]	6	hSpCas9	negative selection	11710130
46896260	46896283	11	-	28162770	HEL	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-1.7383513353551492	[223]	[42]	-7	hSpCas9	negative selection	11710131
46895234	46895257	11	-	28162770	HEL	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.81195121547763	[224]	[252]	7	hSpCas9	negative selection	11710132
46894616	46894639	11	-	28162770	HEL	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.48437308590298234	[248]	[113]	-3	hSpCas9	negative selection	11710133
46893068	46893091	11	-	28162770	HEL	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.19487892877459392	[276]	[154]	-1	hSpCas9	negative selection	11710134
46893019	46893042	11	+	28162770	HEL	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.14831387769280333	[192]	[136]	1	hSpCas9	negative selection	11710135
46892998	46893021	11	-	28162770	HEL	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-0.7692388675294288	[156]	[58]	-5	hSpCas9	negative selection	11710136
46900304	46900327	11	+	28162770	MV411	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.21163682935492859	[203]	[198]	1	hSpCas9	negative selection	11879493
46890276	46890299	11	-	28162770	MV411	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-0.11513252860193303	[170]	[132]	-1	hSpCas9	negative selection	11879494
46899428	46899451	11	-	28162770	MV411	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	-1.3722903680990575	[125]	[40]	-7	hSpCas9	negative selection	11879495
46896914	46896937	11	-	28162770	MV411	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.422311768196821	[193]	[218]	4	hSpCas9	negative selection	11879496
46896260	46896283	11	-	28162770	MV411	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.7238034562358009	[148]	[75]	-5	hSpCas9	negative selection	11879497
46895234	46895257	11	-	28162770	MV411	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.530791940996165	[234]	[285]	5	hSpCas9	negative selection	11879498
46894616	46894639	11	-	28162770	MV411	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.3585865654662105	[206]	[135]	-3	hSpCas9	negative selection	11879499
46893068	46893091	11	-	28162770	MV411	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.5965712536032863	[288]	[160]	-4	hSpCas9	negative selection	11879500
46893019	46893042	11	+	28162770	MV411	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.7887388227077918	[122]	[178]	7	hSpCas9	negative selection	11879501
46892998	46893021	11	-	28162770	MV411	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.476928006603797	[227]	[68]	-7	hSpCas9	negative selection	11879502
46900304	46900327	11	+	28162770	MONOMAC1	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	-0.0867134321535549	[150]	[162]	0	hSpCas9	negative selection	12048859
46890276	46890299	11	-	28162770	MONOMAC1	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-1.3829033923708876	[90]	[39]	-8	hSpCas9	negative selection	12048860
46899428	46899451	11	-	28162770	MONOMAC1	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	-0.48921759855286395	[59]	[48]	-4	hSpCas9	negative selection	12048861
46896914	46896937	11	-	28162770	MONOMAC1	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.5399287471066523	[137]	[229]	5	hSpCas9	negative selection	12048862
46896260	46896283	11	-	28162770	MONOMAC1	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	0.6752076057420736	[117]	[215]	6	hSpCas9	negative selection	12048863
46895234	46895257	11	-	28162770	MONOMAC1	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.6862669282313488	[147]	[272]	6	hSpCas9	negative selection	12048864
46894616	46894639	11	-	28162770	MONOMAC1	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	0.6246259116819337	[128]	[227]	6	hSpCas9	negative selection	12048865
46893068	46893091	11	-	28162770	MONOMAC1	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	-0.14379482578257427	[132]	[137]	-1	hSpCas9	negative selection	12048866
46893019	46893042	11	+	28162770	MONOMAC1	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.12224166941385922	[108]	[135]	1	hSpCas9	negative selection	12048867
46892998	46893021	11	-	28162770	MONOMAC1	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-0.7960745329924326	[102]	[67]	-6	hSpCas9	negative selection	12048868
46900304	46900327	11	+	28162770	OCIAML2	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	1.0828217027337774	[26]	[316]	8	hSpCas9	negative selection	12218225
46890276	46890299	11	-	28162770	OCIAML2	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	-0.5879867758803201	[31]	[117]	-4	hSpCas9	negative selection	12218226
46899428	46899451	11	-	28162770	OCIAML2	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.025065337381907526	[24]	[140]	0	hSpCas9	negative selection	12218227
46896914	46896937	11	-	28162770	OCIAML2	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	1.1696151109801844	[31]	[398]	9	hSpCas9	negative selection	12218228
46896260	46896283	11	-	28162770	OCIAML2	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.8747790083782689	[43]	[132]	-6	hSpCas9	negative selection	12218229
46895234	46895257	11	-	28162770	OCIAML2	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	-0.0164539320563592	[24]	[136]	0	hSpCas9	negative selection	12218230
46894616	46894639	11	-	28162770	OCIAML2	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.7098174891215873	[35]	[121]	-5	hSpCas9	negative selection	12218231
46893068	46893091	11	-	28162770	OCIAML2	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.4038392926739797	[44]	[329]	4	hSpCas9	negative selection	12218232
46893019	46893042	11	+	28162770	OCIAML2	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	0.3166408507721107	[30]	[213]	3	hSpCas9	negative selection	12218233
46892998	46893021	11	-	28162770	OCIAML2	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-1.4706298252421612	[33]	[67]	-7	hSpCas9	negative selection	12218234
46900304	46900327	11	+	28162770	OCIAML3	viability	CGTCACACACCCAGGAGCGGCGG	LRP4	ENSG00000134569	0.5032895610307516	[42]	[183]	4	hSpCas9	negative selection	12387591
46890276	46890299	11	-	28162770	OCIAML3	viability	CGTAAGGCTGTCATTAGCCAGGG	LRP4	ENSG00000134569	0.9689285540669942	[32]	[194]	8	hSpCas9	negative selection	12387592
46899428	46899451	11	-	28162770	OCIAML3	viability	GCTGAGCATTGGTACTGCGACGG	LRP4	ENSG00000134569	0.016717956462074968	[36]	[112]	0	hSpCas9	negative selection	12387593
46896914	46896937	11	-	28162770	OCIAML3	viability	GTCCTGGCGCTGTGATGGGGAGG	LRP4	ENSG00000134569	0.30685916765658533	[63]	[238]	3	hSpCas9	negative selection	12387594
46896260	46896283	11	-	28162770	OCIAML3	viability	GGGCAGAGGAAGCTGTGCAACGG	LRP4	ENSG00000134569	-0.3245469653309364	[55]	[134]	-3	hSpCas9	negative selection	12387595
46895234	46895257	11	-	28162770	OCIAML3	viability	CAGGGCTGCACCAACAGCGAAGG	LRP4	ENSG00000134569	0.37999715114289223	[41]	[164]	3	hSpCas9	negative selection	12387596
46894616	46894639	11	-	28162770	OCIAML3	viability	CAACGGCAGCAACGTGGAGGAGG	LRP4	ENSG00000134569	-0.10572115901468077	[71]	[201]	-1	hSpCas9	negative selection	12387597
46893068	46893091	11	-	28162770	OCIAML3	viability	GGACCGACTCAGGCACCTCGAGG	LRP4	ENSG00000134569	0.5286116463397925	[61]	[269]	5	hSpCas9	negative selection	12387598
46893019	46893042	11	+	28162770	OCIAML3	viability	GCCACAGCAACACTTTCCGGTGG	LRP4	ENSG00000134569	-0.19711748775557866	[59]	[157]	-1	hSpCas9	negative selection	12387599
46892998	46893021	11	-	28162770	OCIAML3	viability	GCAGAACCTGGAGAAGCCCCGGG	LRP4	ENSG00000134569	-0.8515038626165271	[51]	[86]	-6	hSpCas9	negative selection	12387600