Crispr

Gene Info

• Species:Human (Homo sapiens)
• GeneID:5606
• Symbol:MAP2K3
• Description:mitogen-activated protein kinase kinase 3

DataSource: http://genomecrispr.dkfz.de/#!/results/MAP2K3

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Start	The end	chr	strand	pubmed	cellline	condition	sequence	symbol	ensg	log2fc	rc_initial	rc_final	effect	cas	screentype	index
21300589	21300612	17	+	26472758	Jiyoye	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-2.351816518990332	[87]	[12]	-8	hSpCas9	negative selection	95896
21298464	21298487	17	-	26472758	Jiyoye	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	1.111977652233033	[126]	[206]	7	hSpCas9	negative selection	95897
21300884	21300907	17	-	26472758	Jiyoye	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	0.7378206934943446	[131]	[165]	5	hSpCas9	negative selection	95898
21312192	21312215	17	+	26472758	Jiyoye	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-0.3650187009713144	[151]	[88]	-3	hSpCas9	negative selection	95899
21300617	21300640	17	+	26472758	Jiyoye	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.8464604270313946	[117]	[159]	6	hSpCas9	negative selection	95900
21302238	21302261	17	-	26472758	Jiyoye	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.5933808041756574	[420]	[478]	4	hSpCas9	negative selection	95901
21303213	21303236	17	+	26472758	Jiyoye	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.3601638617038516	[239]	[140]	-3	hSpCas9	negative selection	95902
21304439	21304462	17	+	26472758	Jiyoye	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-1.177787119215283	[125]	[41]	-7	hSpCas9	negative selection	95903
21305107	21305130	17	+	26472758	Jiyoye	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-3.570104541994043	[62]	[3]	-9	hSpCas9	negative selection	95904
21312252	21312275	17	-	26472758	Jiyoye	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.5599599845884999	[216]	[110]	-4	hSpCas9	negative selection	95905
21307944	21307967	17	-	26472758	Jiyoye	viability	GGAGAATTGCCTGAACGCGAGAG	MAP2K3	ENSG00000034152	3.169676067779217	[13]	[94]	9	hSpCas9	negative selection	128967
21300589	21300612	17	+	26472758	KBM7	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-1.8466853020813154	[371,206]	[9,60]	-8	hSpCas9	negative selection	287014
21298464	21298487	17	-	26472758	KBM7	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.320339239868243	[554,600]	[325,356]	3	hSpCas9	negative selection	287015
21300884	21300907	17	-	26472758	KBM7	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	0.344016774836345	[840,431]	[430,313]	3	hSpCas9	negative selection	287016
21312192	21312215	17	+	26472758	KBM7	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-0.6386288116489275	[464,199]	[71,118]	-5	hSpCas9	negative selection	287017
21300617	21300640	17	+	26472758	KBM7	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.09920544065390047	[1061,790]	[434,485]	1	hSpCas9	negative selection	287018
21302238	21302261	17	-	26472758	KBM7	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.09609382269585809	[2108,1418]	[870,874]	0	hSpCas9	negative selection	287019
21303213	21303236	17	+	26472758	KBM7	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.22058281574476946	[900,979]	[335,424]	-2	hSpCas9	negative selection	287020
21304439	21304462	17	+	26472758	KBM7	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.0638524973206788	[348,491]	[262,164]	0	hSpCas9	negative selection	287021
21305107	21305130	17	+	26472758	KBM7	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-2.4664135560200044	[157,142]	[25,0]	-9	hSpCas9	negative selection	287022
21312252	21312275	17	-	26472758	KBM7	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.14156181417955094	[518,567]	[245,222]	-1	hSpCas9	negative selection	287023
21307944	21307967	17	-	26472758	KBM7	viability	GGAGAATTGCCTGAACGCGAGAG	MAP2K3	ENSG00000034152	0.603216228269114	[190,124]	[214,17]	6	hSpCas9	negative selection	320085
21300589	21300612	17	+	26472758	Raji	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-2.4875630539201787	[144]	[5]	-9	hSpCas9	negative selection	478132
21298464	21298487	17	-	26472758	Raji	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.03803548868286463	[276]	[65]	0	hSpCas9	negative selection	478133
21300884	21300907	17	-	26472758	Raji	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	0.5790045630188109	[224]	[77]	5	hSpCas9	negative selection	478134
21312192	21312215	17	+	26472758	Raji	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	0.0663562671135447	[106]	[25]	0	hSpCas9	negative selection	478135
21300617	21300640	17	+	26472758	Raji	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.028934437688249992	[358]	[84]	0	hSpCas9	negative selection	478136
21302238	21302261	17	-	26472758	Raji	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-0.29263692826452115	[891]	[168]	-2	hSpCas9	negative selection	478137
21303213	21303236	17	+	26472758	Raji	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.17607041169912713	[369]	[75]	-1	hSpCas9	negative selection	478138
21304439	21304462	17	+	26472758	Raji	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-0.951510153679969	[199]	[23]	-6	hSpCas9	negative selection	478139
21305107	21305130	17	+	26472758	Raji	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-1.4775789653475564	[47]	[3]	-8	hSpCas9	negative selection	478140
21312252	21312275	17	-	26472758	Raji	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.2925470715150359	[379]	[71]	-2	hSpCas9	negative selection	478141
21307944	21307967	17	-	26472758	Raji	viability	GGAGAATTGCCTGAACGCGAGAG	MAP2K3	ENSG00000034152	-0.7505974597539726	[57]	[7]	-5	hSpCas9	negative selection	511203
21300589	21300612	17	+	26472758	K562	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-4.03686738272357	[174]	[8]	-9	hSpCas9	negative selection	669250
21298464	21298487	17	-	26472758	K562	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.16671637067320288	[533]	[505]	1	hSpCas9	negative selection	669251
21300884	21300907	17	-	26472758	K562	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.9215912237724825	[367]	[163]	-5	hSpCas9	negative selection	669252
21312192	21312215	17	+	26472758	K562	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-2.914779867182807	[267]	[29]	-8	hSpCas9	negative selection	669253
21300617	21300640	17	+	26472758	K562	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	-0.6611656704414465	[827]	[441]	-4	hSpCas9	negative selection	669254
21302238	21302261	17	-	26472758	K562	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-1.0505616936266076	[1378]	[561]	-5	hSpCas9	negative selection	669255
21303213	21303236	17	+	26472758	K562	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.620330200314997	[640]	[351]	-4	hSpCas9	negative selection	669256
21304439	21304462	17	+	26472758	K562	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-0.6593659570742499	[231]	[123]	-4	hSpCas9	negative selection	669257
21305107	21305130	17	+	26472758	K562	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-1.8380434325255264	[71]	[16]	-7	hSpCas9	negative selection	669258
21312252	21312275	17	-	26472758	K562	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-1.2336285691381974	[467]	[167]	-6	hSpCas9	negative selection	669259
21307944	21307967	17	-	26472758	K562	viability	GGAGAATTGCCTGAACGCGAGAG	MAP2K3	ENSG00000034152	0.16913060036220973	[58]	[55]	1	hSpCas9	negative selection	702321
21284959	21284982	17	-	26627737	DLD1	viability	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.5833318904455634	[206]	[60,84,137]	6	hSpCas9	negative selection	796556
21295690	21295713	17	+	26627737	DLD1	viability	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-1.481267815969592	[624]	[96,31,77]	-8	hSpCas9	negative selection	796557
21295740	21295763	17	-	26627737	DLD1	viability	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.5477680067640944	[165]	[47,99,79]	5	hSpCas9	negative selection	796558
21298881	21298904	17	-	26627737	DLD1	viability	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.7534105754443454	[353]	[85,90,26]	-6	hSpCas9	negative selection	796559
21302181	21302204	17	+	26627737	DLD1	viability	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.35519568097404586	[307]	[129,33,61]	-4	hSpCas9	negative selection	796560
21303213	21303236	17	+	26627737	DLD1	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.8403089149495189	[1137]	[190,215,190]	-7	hSpCas9	negative selection	796561
21284959	21284982	17	-	26627737	GBM cells	viability after 5 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.12214774064214395	[137]	[37,97]	-2	hSpCas9	negative selection	878871
21295690	21295713	17	+	26627737	GBM cells	viability after 5 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	0.005829078802197629	[181]	[102,92]	0	hSpCas9	negative selection	878872
21295740	21295763	17	-	26627737	GBM cells	viability after 5 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.37084639413642173	[128]	[42,63]	-5	hSpCas9	negative selection	878873
21298881	21298904	17	-	26627737	GBM cells	viability after 5 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.025137271881016	[147]	[71,83]	0	hSpCas9	negative selection	878874
21302181	21302204	17	+	26627737	GBM cells	viability after 5 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	0.337602642229175	[120]	[76,86]	5	hSpCas9	negative selection	878875
21303213	21303236	17	+	26627737	GBM cells	viability after 5 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.20684818770103852	[480]	[222,223]	-3	hSpCas9	negative selection	878876
21284959	21284982	17	-	26627737	GBM cells	viability after 13 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.20193883950456992	[137]	[132,47]	2	hSpCas9	negative selection	961186
21295690	21295713	17	+	26627737	GBM cells	viability after 13 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	0.12269867857390865	[181]	[101,111]	1	hSpCas9	negative selection	961187
21295740	21295763	17	-	26627737	GBM cells	viability after 13 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.11461130214591475	[128]	[46,78]	-1	hSpCas9	negative selection	961188
21298881	21298904	17	-	26627737	GBM cells	viability after 13 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.1742528151263717	[147]	[67,108]	2	hSpCas9	negative selection	961189
21302181	21302204	17	+	26627737	GBM cells	viability after 13 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	0.4682340823215939	[120]	[81,97]	6	hSpCas9	negative selection	961190
21303213	21303236	17	+	26627737	GBM cells	viability after 13 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.5462872877659899	[480]	[154,197]	-6	hSpCas9	negative selection	961191
21284959	21284982	17	-	26627737	GBM cells	viability after 21 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.36396742297582996	[137]	[63,52]	-3	hSpCas9	negative selection	1043501
21295690	21295713	17	+	26627737	GBM cells	viability after 21 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.20502930475726988	[181]	[90,80]	-2	hSpCas9	negative selection	1043502
21295740	21295763	17	-	26627737	GBM cells	viability after 21 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.6493453095073672	[128]	[99,118]	6	hSpCas9	negative selection	1043503
21298881	21298904	17	-	26627737	GBM cells	viability after 21 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.17716465954507998	[147]	[92,88]	2	hSpCas9	negative selection	1043504
21302181	21302204	17	+	26627737	GBM cells	viability after 21 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.0585538463469204	[120]	[71,54]	0	hSpCas9	negative selection	1043505
21303213	21303236	17	+	26627737	GBM cells	viability after 21 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.5115093591888533	[480]	[175,189]	-4	hSpCas9	negative selection	1043506
21284959	21284982	17	-	26627737	RPE1	viability after 9 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.22729467169693873	[383]	[131,151]	1	hSpCas9	negative selection	1125816
21295690	21295713	17	+	26627737	RPE1	viability after 9 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-1.6540730830562058	[525]	[57,44]	-8	hSpCas9	negative selection	1125817
21295740	21295763	17	-	26627737	RPE1	viability after 9 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.4505845202160548	[361]	[109,47]	-3	hSpCas9	negative selection	1125818
21298881	21298904	17	-	26627737	RPE1	viability after 9 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-3.136581373755815	[526]	[23,11]	-9	hSpCas9	negative selection	1125819
21302181	21302204	17	+	26627737	RPE1	viability after 9 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.08824215688278439	[846]	[248,249]	0	hSpCas9	negative selection	1125820
21303213	21303236	17	+	26627737	RPE1	viability after 9 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.3385854972591358	[1124]	[726,1101]	7	hSpCas9	negative selection	1125821
21284959	21284982	17	-	26627737	RPE1	viability after 12 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.2401959202126679	[383]	[116,126]	1	hSpCas9	negative selection	1208131
21295690	21295713	17	+	26627737	RPE1	viability after 12 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.8851503492398206	[525]	[110,39]	-6	hSpCas9	negative selection	1208132
21295740	21295763	17	-	26627737	RPE1	viability after 12 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-1.054417353255575	[361]	[74,16]	-6	hSpCas9	negative selection	1208133
21298881	21298904	17	-	26627737	RPE1	viability after 12 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-2.3264635253243657	[526]	[52,1]	-9	hSpCas9	negative selection	1208134
21302181	21302204	17	+	26627737	RPE1	viability after 12 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.02496172397722364	[846]	[279,163]	0	hSpCas9	negative selection	1208135
21303213	21303236	17	+	26627737	RPE1	viability after 12 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.1538232294220236	[1124]	[621,725]	7	hSpCas9	negative selection	1208136
21284959	21284982	17	-	26627737	RPE1	viability after 15 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.7264436552470299	[383]	[166,191]	4	hSpCas9	negative selection	1290446
21295690	21295713	17	+	26627737	RPE1	viability after 15 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-2.382906432938709	[525]	[26,29]	-8	hSpCas9	negative selection	1290447
21295740	21295763	17	-	26627737	RPE1	viability after 15 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-3.284536691332727	[361]	[9,10]	-9	hSpCas9	negative selection	1290448
21298881	21298904	17	-	26627737	RPE1	viability after 15 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-2.5717520076916536	[526]	[48,1]	-8	hSpCas9	negative selection	1290449
21302181	21302204	17	+	26627737	RPE1	viability after 15 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.03467657948762738	[846]	[210,255]	0	hSpCas9	negative selection	1290450
21303213	21303236	17	+	26627737	RPE1	viability after 15 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.6068740493491287	[1124]	[922,1013]	8	hSpCas9	negative selection	1290451
21284959	21284982	17	-	26627737	RPE1	viability after 18 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.8833869735309412	[383]	[195,185]	5	hSpCas9	negative selection	1372761
21295690	21295713	17	+	26627737	RPE1	viability after 18 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-1.402489677190867	[525]	[73,31]	-7	hSpCas9	negative selection	1372762
21295740	21295763	17	-	26627737	RPE1	viability after 18 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-1.2311072845597413	[361]	[44,37]	-6	hSpCas9	negative selection	1372763
21298881	21298904	17	-	26627737	RPE1	viability after 18 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-1.9479065608094492	[526]	[61,9]	-8	hSpCas9	negative selection	1372764
21302181	21302204	17	+	26627737	RPE1	viability after 18 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	0.23020247030242202	[846]	[227,310]	1	hSpCas9	negative selection	1372765
21303213	21303236	17	+	26627737	RPE1	viability after 18 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.450572229095477	[1124]	[648,1022]	7	hSpCas9	negative selection	1372766
21284959	21284982	17	-	26627737	HeLa	viability after 8 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.10728895443802422	[169]	[216,12,41]	1	hSpCas9	negative selection	1455076
21295690	21295713	17	+	26627737	HeLa	viability after 8 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.22628920905028593	[388]	[176,249,22]	-2	hSpCas9	negative selection	1455077
21295740	21295763	17	-	26627737	HeLa	viability after 8 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	1.0906756748605024	[78]	[146,61,29]	8	hSpCas9	negative selection	1455078
21298881	21298904	17	-	26627737	HeLa	viability after 8 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.3308821862052146	[395]	[439,170,96]	3	hSpCas9	negative selection	1455079
21302181	21302204	17	+	26627737	HeLa	viability after 8 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	0.033435832904936263	[338]	[136,193,120]	0	hSpCas9	negative selection	1455080
21303213	21303236	17	+	26627737	HeLa	viability after 8 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.5647775773729018	[302]	[551,281,372]	9	hSpCas9	negative selection	1455081
21284959	21284982	17	-	26627737	HeLa	viability after 12 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	1.555829548755418	[169]	[314,166,144]	9	hSpCas9	negative selection	1537391
21295690	21295713	17	+	26627737	HeLa	viability after 12 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.9978882317109475	[388]	[55,68,116]	-7	hSpCas9	negative selection	1537392
21295740	21295763	17	-	26627737	HeLa	viability after 12 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	1.6393815682043766	[78]	[122,70,114]	9	hSpCas9	negative selection	1537393
21298881	21298904	17	-	26627737	HeLa	viability after 12 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.29547978999338587	[395]	[21,121,253]	-3	hSpCas9	negative selection	1537394
21302181	21302204	17	+	26627737	HeLa	viability after 12 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.041654933498690094	[338]	[199,118,92]	0	hSpCas9	negative selection	1537395
21303213	21303236	17	+	26627737	HeLa	viability after 12 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.087514861624335	[302]	[301,174,331]	7	hSpCas9	negative selection	1537396
21284959	21284982	17	-	26627737	HeLa	viability after 15 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	1.2869929855010367	[169]	[95,140,278]	8	hSpCas9	negative selection	1619706
21295690	21295713	17	+	26627737	HeLa	viability after 15 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.8671307355056622	[388]	[0,83,183]	-6	hSpCas9	negative selection	1619707
21295740	21295763	17	-	26627737	HeLa	viability after 15 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	1.2076580395316892	[78]	[93,0,131]	8	hSpCas9	negative selection	1619708
21298881	21298904	17	-	26627737	HeLa	viability after 15 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.4966725847945779	[395]	[55,82,211]	-4	hSpCas9	negative selection	1619709
21302181	21302204	17	+	26627737	HeLa	viability after 15 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.2491429096851322	[338]	[144,134,63]	-2	hSpCas9	negative selection	1619710
21303213	21303236	17	+	26627737	HeLa	viability after 15 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.536537537367419	[302]	[533,266,262]	8	hSpCas9	negative selection	1619711
21284959	21284982	17	-	26627737	HeLa	viability after 18 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	1.2930664572167099	[169]	[63,118,278]	8	hSpCas9	negative selection	1702021
21295690	21295713	17	+	26627737	HeLa	viability after 18 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.8818502767167691	[388]	[0,66,183]	-6	hSpCas9	negative selection	1702022
21295740	21295763	17	-	26627737	HeLa	viability after 18 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	1.1471623786023537	[78]	[56,0,131]	7	hSpCas9	negative selection	1702023
21298881	21298904	17	-	26627737	HeLa	viability after 18 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.4873235105197935	[395]	[37,69,211]	-4	hSpCas9	negative selection	1702024
21302181	21302204	17	+	26627737	HeLa	viability after 18 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.2769841936414734	[338]	[87,117,63]	-2	hSpCas9	negative selection	1702025
21303213	21303236	17	+	26627737	HeLa	viability after 18 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	1.516158796026202	[302]	[354,212,262]	8	hSpCas9	negative selection	1702026
21284959	21284982	17	-	26627737	HCT116	viability after 6 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.8684812528496727	[318]	[204,28]	5	hSpCas9	negative selection	1784336
21295690	21295713	17	+	26627737	HCT116	viability after 6 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.41509964503309055	[1137]	[177,109]	-2	hSpCas9	negative selection	1784337
21295740	21295763	17	-	26627737	HCT116	viability after 6 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	1.6254449965328426	[371]	[367,76]	8	hSpCas9	negative selection	1784338
21298881	21298904	17	-	26627737	HCT116	viability after 6 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.24761390837888697	[411]	[60,50]	-1	hSpCas9	negative selection	1784339
21302181	21302204	17	+	26627737	HCT116	viability after 6 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	2.5268578452594417	[130]	[128,112]	9	hSpCas9	negative selection	1784340
21303213	21303236	17	+	26627737	HCT116	viability after 6 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.7655503076350216	[1042]	[60,115]	-4	hSpCas9	negative selection	1784341
21284959	21284982	17	-	26627737	HCT116	viability after 8 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.3138429557642328	[131]	[52,26,94]	-4	hSpCas9	negative selection	1866651
21295690	21295713	17	+	26627737	HCT116	viability after 8 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-1.0390922901708661	[353]	[106,83,93]	-8	hSpCas9	negative selection	1866652
21295740	21295763	17	-	26627737	HCT116	viability after 8 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.6538652956012442	[100]	[68,75,116]	6	hSpCas9	negative selection	1866653
21298881	21298904	17	-	26627737	HCT116	viability after 8 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.27820359616348656	[121]	[105,56,81]	3	hSpCas9	negative selection	1866654
21302181	21302204	17	+	26627737	HCT116	viability after 8 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-1.4898545759629644	[328]	[75,65,51]	-9	hSpCas9	negative selection	1866655
21303213	21303236	17	+	26627737	HCT116	viability after 8 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.02778900642293658	[412]	[271,210,187]	0	hSpCas9	negative selection	1866656
21284959	21284982	17	-	26627737	HCT116	viability after 9 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.26458252766335466	[318]	[103,100]	2	hSpCas9	negative selection	1948966
21295690	21295713	17	+	26627737	HCT116	viability after 9 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-2.013977647550387	[1137]	[10,125]	-8	hSpCas9	negative selection	1948967
21295740	21295763	17	-	26627737	HCT116	viability after 9 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.0008791846518547697	[371]	[110,89]	0	hSpCas9	negative selection	1948968
21298881	21298904	17	-	26627737	HCT116	viability after 9 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.2290110898720525	[411]	[243,37]	1	hSpCas9	negative selection	1948969
21302181	21302204	17	+	26627737	HCT116	viability after 9 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	0.8305766426113255	[130]	[126,10]	6	hSpCas9	negative selection	1948970
21303213	21303236	17	+	26627737	HCT116	viability after 9 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.03469752190858355	[1042]	[191,358]	0	hSpCas9	negative selection	1948971
21284959	21284982	17	-	26627737	HCT116	viability after 12 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.03389121081830493	[131]	[51,122,30]	0	hSpCas9	negative selection	2031281
21295690	21295713	17	+	26627737	HCT116	viability after 12 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-2.140986794887382	[353]	[42,22,59]	-9	hSpCas9	negative selection	2031282
21295740	21295763	17	-	26627737	HCT116	viability after 12 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.34001685180439356	[100]	[62,43,16]	-4	hSpCas9	negative selection	2031283
21298881	21298904	17	-	26627737	HCT116	viability after 12 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.7239532675656538	[121]	[73,167,79]	6	hSpCas9	negative selection	2031284
21302181	21302204	17	+	26627737	HCT116	viability after 12 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-1.2960199378472703	[328]	[70,103,36]	-8	hSpCas9	negative selection	2031285
21303213	21303236	17	+	26627737	HCT116	viability after 12 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.19999363585000002	[412]	[217,176,168]	-2	hSpCas9	negative selection	2031286
21284959	21284982	17	-	26627737	HCT116	viability after 15 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.12746258503318675	[131]	[69,46,90]	-1	hSpCas9	negative selection	2113596
21295690	21295713	17	+	26627737	HCT116	viability after 15 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-1.6741273865565207	[353]	[70,56,63]	-9	hSpCas9	negative selection	2113597
21295740	21295763	17	-	26627737	HCT116	viability after 15 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.8242836005088461	[100]	[55,107,137]	7	hSpCas9	negative selection	2113598
21298881	21298904	17	-	26627737	HCT116	viability after 15 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.5790904573719227	[121]	[83,164,62]	5	hSpCas9	negative selection	2113599
21302181	21302204	17	+	26627737	HCT116	viability after 15 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-2.603076836507964	[328]	[36,24,31]	-9	hSpCas9	negative selection	2113600
21303213	21303236	17	+	26627737	HCT116	viability after 15 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.13660868050503222	[412]	[310,143,203]	-1	hSpCas9	negative selection	2113601
21284959	21284982	17	-	26627737	HCT116	viability after 18 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.6217727677384499	[131]	[50,23,50]	-5	hSpCas9	negative selection	2195911
21295690	21295713	17	+	26627737	HCT116	viability after 18 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.6921264069248989	[353]	[81,130,102]	-6	hSpCas9	negative selection	2195912
21295740	21295763	17	-	26627737	HCT116	viability after 18 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.6655585183972297	[100]	[42,8,189]	5	hSpCas9	negative selection	2195913
21298881	21298904	17	-	26627737	HCT116	viability after 18 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.2998223627913369	[121]	[35,145,28]	2	hSpCas9	negative selection	2195914
21302181	21302204	17	+	26627737	HCT116	viability after 18 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-1.982414641667271	[328]	[48,25,46]	-9	hSpCas9	negative selection	2195915
21303213	21303236	17	+	26627737	HCT116	viability after 18 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.6898109542982477	[412]	[154,130,82]	-6	hSpCas9	negative selection	2195916
21298883	21298906	17	-	24336569	HL60	viability	GGTCCGGGAGTCCAGGTTCCGGG	MAP2K3	ENSG00000034152	-0.5085744322083152	[399]	[594]	-4	hSpCas9	negative selection	2275768
21298890	21298913	17	-	24336569	HL60	viability	TGATGAAGGTCCGGGAGTCCAGG	MAP2K3	ENSG00000034152	-2.3652570666294874	[55]	[22]	-9	hSpCas9	negative selection	2275769
21298897	21298920	17	+	24336569	HL60	viability	TCCCGGACCTTCATCACCATTGG	MAP2K3	ENSG00000034152	0.613155202827715	[362]	[1174]	5	hSpCas9	negative selection	2275770
21298904	21298927	17	-	24336569	HL60	viability	TCTGTCTCCAATGGTGATGAAGG	MAP2K3	ENSG00000034152	0.446944061011604	[658]	[1900]	4	hSpCas9	negative selection	2275771
21298913	21298936	17	-	24336569	HL60	viability	GGCACCTACTCTGTCTCCAATGG	MAP2K3	ENSG00000034152	-0.6389458649279458	[38]	[52]	-5	hSpCas9	negative selection	2275772
21300532	21300555	17	+	24336569	HL60	viability	TCCATCCTTCAAGAACTTTGAGG	MAP2K3	ENSG00000034152	0.6098946302843766	[330]	[1068]	5	hSpCas9	negative selection	2275773
21300538	21300561	17	+	24336569	HL60	viability	CTTCAAGAACTTTGAGGTGGAGG	MAP2K3	ENSG00000034152	0.14469023950375082	[765]	[1791]	1	hSpCas9	negative selection	2275774
21300550	21300573	17	+	24336569	HL60	viability	TGAGGTGGAGGCTGATGACTTGG	MAP2K3	ENSG00000034152	0.13091688324360073	[784]	[1818]	1	hSpCas9	negative selection	2275775
21300568	21300591	17	+	24336569	HL60	viability	CTTGGTGACCATCTCAGAACTGG	MAP2K3	ENSG00000034152	0.40969403196809384	[322]	[907]	4	hSpCas9	negative selection	2275776
21300575	21300598	17	+	24336569	HL60	viability	ACCATCTCAGAACTGGGCCGTGG	MAP2K3	ENSG00000034152	0.7645901557746366	[288]	[1038]	6	hSpCas9	negative selection	2275777
21298883	21298906	17	-	24336569	KBM7	viability	GGTCCGGGAGTCCAGGTTCCGGG	MAP2K3	ENSG00000034152	-0.33480112872990186	[534]	[1156]	-3	hSpCas9	negative selection	2342945
21298890	21298913	17	-	24336569	KBM7	viability	TGATGAAGGTCCGGGAGTCCAGG	MAP2K3	ENSG00000034152	-0.5612359783444498	[32]	[60]	-4	hSpCas9	negative selection	2342946
21298897	21298920	17	+	24336569	KBM7	viability	TCCCGGACCTTCATCACCATTGG	MAP2K3	ENSG00000034152	0.6803735344181138	[247]	[1083]	6	hSpCas9	negative selection	2342947
21298904	21298927	17	-	24336569	KBM7	viability	TCTGTCTCCAATGGTGATGAAGG	MAP2K3	ENSG00000034152	0.7907868609953059	[493]	[2330]	7	hSpCas9	negative selection	2342948
21298913	21298936	17	-	24336569	KBM7	viability	GGCACCTACTCTGTCTCCAATGG	MAP2K3	ENSG00000034152	-5.971141152605894	[22]	[0]	-9	hSpCas9	negative selection	2342949
21300532	21300555	17	+	24336569	KBM7	viability	TCCATCCTTCAAGAACTTTGAGG	MAP2K3	ENSG00000034152	1.3342406334015842	[398]	[2743]	9	hSpCas9	negative selection	2342950
21300538	21300561	17	+	24336569	KBM7	viability	CTTCAAGAACTTTGAGGTGGAGG	MAP2K3	ENSG00000034152	0.00012679609641019773	[583]	[1592]	0	hSpCas9	negative selection	2342951
21300550	21300573	17	+	24336569	KBM7	viability	TGAGGTGGAGGCTGATGACTTGG	MAP2K3	ENSG00000034152	0.030877247770171312	[903]	[2518]	0	hSpCas9	negative selection	2342952
21300568	21300591	17	+	24336569	KBM7	viability	CTTGGTGACCATCTCAGAACTGG	MAP2K3	ENSG00000034152	-0.12113562053902721	[318]	[799]	-1	hSpCas9	negative selection	2342953
21300575	21300598	17	+	24336569	KBM7	viability	ACCATCTCAGAACTGGGCCGTGG	MAP2K3	ENSG00000034152	0.7964216423316365	[212]	[1008]	7	hSpCas9	negative selection	2342954
21287915	21287938	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TCCGACAGCCAGGGGTTGGGGGG	MAP2K3	ENSG00000034152	1.7609175255842788	[17,92]	[6,78]	6	dCas9-VP64	positive selection	2431052
21287852	21287875	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGAAACCTCAGTGTCACCATCGG	MAP2K3	ENSG00000034152	1.584906736779913	[278,144]	[165,110]	6	dCas9-VP64	positive selection	2431053
21287891	21287914	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	TGGCCACAGCAGGCAGGGCTAGG	MAP2K3	ENSG00000034152	0.41827723380478243	[2,5]	[0,0]	1	dCas9-VP64	positive selection	2431054
21306681	21306704	17	-	25494202	A375	resistance to PLX-4720 (puromycin)	CAAGACCAGCCTCGCCAACATGG	MAP2K3	ENSG00000034152	0.26554877243276964	[151,147]	[20,58]	1	dCas9-VP64	positive selection	2476674
21287915	21287938	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TCCGACAGCCAGGGGTTGGGGGG	MAP2K3	ENSG00000034152	-0.5174405074624253	[36,51]	[9,9]	-5	dCas9-VP64	positive selection	2526307
21287852	21287875	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGAAACCTCAGTGTCACCATCGG	MAP2K3	ENSG00000034152	0.669127075386055	[253,317]	[237,63]	5	dCas9-VP64	positive selection	2526308
21287891	21287914	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	TGGCCACAGCAGGCAGGGCTAGG	MAP2K3	ENSG00000034152	0.6360503461464944	[52,6]	[14,14]	5	dCas9-VP64	positive selection	2526309
21306681	21306704	17	-	25494202	A375	resistance to PLX-4720 (zeocin)	CAAGACCAGCCTCGCCAACATGG	MAP2K3	ENSG00000034152	3.0708898277967998	[136,69]	[553,38]	9	dCas9-VP64	positive selection	2571929
21300925	21300948	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CCTGGACATCAACATGCGCACGG	MAP2K3	ENSG00000034152	0.37956759426134734	[3,3]	[5,3]	7	hSpCas9	positive selection	3001110
21300958	21300981	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACACTGTCACCTTCTACGGGG	MAP2K3	ENSG00000034152	0.5941738413005524	[3,3]	[3,6]	9	hSpCas9	positive selection	3001111
21300973	21300996	17	+	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTACGGGGCACTATTCAGAGAGG	MAP2K3	ENSG00000034152	0.050063331898699624	[3,3]	[3,1]	1	hSpCas9	positive selection	3001112
21302180	21302203	17	-	27453484	HT29	resistance to T3SS1-dependent cytotoxicity	CTTCCGGTAGAACTTGTCCAAGG	MAP2K3	ENSG00000034152	0.5365533283585269	[3,3]	[4,4]	9	hSpCas9	positive selection	3001113
21300925	21300948	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CCTGGACATCAACATGCGCACGG	MAP2K3	ENSG00000034152	0.3839771179410595	[3,3]	[3,3]	6	hSpCas9	positive selection	3068968
21300958	21300981	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACACTGTCACCTTCTACGGGG	MAP2K3	ENSG00000034152	0.2187961397387828	[3,3]	[3,2]	4	hSpCas9	positive selection	3068969
21300973	21300996	17	+	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTACGGGGCACTATTCAGAGAGG	MAP2K3	ENSG00000034152	-0.07392861766562732	[3,3]	[3,1]	-1	hSpCas9	positive selection	3068970
21302180	21302203	17	-	27453484	HT29	resistance to T3SS2-dependent cytotoxicity	CTTCCGGTAGAACTTGTCCAAGG	MAP2K3	ENSG00000034152	-0.142162437134925	[3,3]	[3,1]	-2	hSpCas9	positive selection	3068971
21302187	21302210		+	24336571	A375	resistance to PLX after 7 days	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.04527037053541455	[15,15]	[15,14]	-1	hSpCas9	positive selection	3126250
21300924	21300947		-	24336571	A375	resistance to PLX after 7 days	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.2336539956269812	[28,23]	[29,30]	7	hSpCas9	positive selection	3126251
21302187	21302210		+	24336571	A375	resistance to PLX after 14 days	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.5404652560363946	[21,16]	[5,5]	-6	hSpCas9	positive selection	3184043
21300924	21300947		-	24336571	A375	resistance to PLX after 14 days	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.4614784128696443	[21,25]	[17,12]	4	hSpCas9	positive selection	3184044
21302187	21302210		+	24336571	A375	viability after 7 days	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	0.018227459278057967	[16]	[15,15]	0	hSpCas9	negative selection	3241836
21300924	21300947		-	24336571	A375	viability after 7 days	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.6371400742758324	[16]	[28,23]	8	hSpCas9	negative selection	3241837
21302187	21302210		+	24336571	A375	viability after 14 days	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	0.28399164190186627	[16]	[21,16]	3	hSpCas9	negative selection	3299629
21300924	21300947		-	24336571	A375	viability after 14 days	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.5436648760832972	[16]	[21,25]	7	hSpCas9	negative selection	3299630
21300924	21300947	17	-	27383988	293T	resistance to West Nile virus (flavivirus)	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.6426163673306269	[97,97]	[0,0]	3	hSpCas9	positive selection	3378376
21302187	21302210	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.8407058715146917	[273,273]	[0,0]	-6	hSpCas9	positive selection	3378377
21302163	21302186	17	+	27383988	293T	resistance to West Nile virus (flavivirus)	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.7026757206222457	[248,248]	[0,0]	-5	hSpCas9	positive selection	3378378
21300924	21300947	17	+	26780180	HT29	viability (Avana library 4 designs)	CCTGGACATCAACATGCGCACGG	MAP2K3	ENSG00000034152	0.431752132517026	[]	[]	1	hSpCas9	negative selection	3438752
21300957	21300980	17	+	26780180	HT29	viability (Avana library 4 designs)	CTACACTGTCACCTTCTACGGGG	MAP2K3	ENSG00000034152	0.328130857203745	[]	[]	1	hSpCas9	negative selection	3438753
21300972	21300995	17	+	26780180	HT29	viability (Avana library 4 designs)	CTACGGGGCACTATTCAGAGAGG	MAP2K3	ENSG00000034152	1.19122149912521	[]	[]	4	hSpCas9	negative selection	3438754
21302180	21302203	17	-	26780180	HT29	viability (Avana library 4 designs)	CTTCCGGTAGAACTTGTCCAAGG	MAP2K3	ENSG00000034152	0.562713431363592	[]	[]	2	hSpCas9	negative selection	3438755
21300957	21300980	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACACTGTCACCTTCTACGGGG	MAP2K3	ENSG00000034152	0.688893341072462	[]	[]	1	hSpCas9	negative selection	3528159
21300972	21300995	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CTACGGGGCACTATTCAGAGAGG	MAP2K3	ENSG00000034152	6.5432149870415	[]	[]	9	hSpCas9	negative selection	3528160
21302180	21302203	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTTCCGGTAGAACTTGTCCAAGG	MAP2K3	ENSG00000034152	3.57700827446722	[]	[]	5	hSpCas9	negative selection	3528161
21300924	21300947	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	CCTGGACATCAACATGCGCACGG	MAP2K3	ENSG00000034152	0.505206466446171	[]	[]	0	hSpCas9	negative selection	3528162
21298865	21298888	17	+	26780180	A375	viability (Avana lentiCRISPRv2)	TCTTTCTCCACAGACCCCCCCGG	MAP2K3	ENSG00000034152	3.13459034542169	[]	[]	5	hSpCas9	negative selection	3528163
21300592	21300615	17	-	26780180	A375	viability (Avana lentiCRISPRv2)	CTACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	1.87377881431181	[]	[]	2	hSpCas9	negative selection	3528164
21300957	21300980	17	+	26780180	A375	viability (Avana lentiGuide)	CTACACTGTCACCTTCTACGGGG	MAP2K3	ENSG00000034152	-3.48864483995175	[]	[]	-6	hSpCas9	negative selection	3636818
21300972	21300995	17	+	26780180	A375	viability (Avana lentiGuide)	CTACGGGGCACTATTCAGAGAGG	MAP2K3	ENSG00000034152	-3.5003481887721	[]	[]	-6	hSpCas9	negative selection	3636819
21302180	21302203	17	-	26780180	A375	viability (Avana lentiGuide)	CTTCCGGTAGAACTTGTCCAAGG	MAP2K3	ENSG00000034152	0.170914344788772	[]	[]	0	hSpCas9	negative selection	3636820
21300924	21300947	17	+	26780180	A375	viability (Avana lentiGuide)	CCTGGACATCAACATGCGCACGG	MAP2K3	ENSG00000034152	0.28768087890419	[]	[]	0	hSpCas9	negative selection	3636821
21298865	21298888	17	+	26780180	A375	viability (Avana lentiGuide)	TCTTTCTCCACAGACCCCCCCGG	MAP2K3	ENSG00000034152	-4.03943312012309	[]	[]	-7	hSpCas9	negative selection	3636822
21300592	21300615	17	-	26780180	A375	viability (Avana lentiGuide)	CTACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-2.81881889946808	[]	[]	-5	hSpCas9	negative selection	3636823
21300957	21300980	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACACTGTCACCTTCTACGGGG	MAP2K3	ENSG00000034152	-0.4189644149935914	[5]	[3,3]	-6	hSpCas9	positive selection	3745477
21300972	21300995	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACGGGGCACTATTCAGAGAGG	MAP2K3	ENSG00000034152	0.1918599564733094	[4]	[5,5]	5	hSpCas9	positive selection	3745478
21302180	21302203	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTTCCGGTAGAACTTGTCCAAGG	MAP2K3	ENSG00000034152	0.15778088801468154	[5]	[6,5]	4	hSpCas9	positive selection	3745479
21300924	21300947	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CCTGGACATCAACATGCGCACGG	MAP2K3	ENSG00000034152	0.09960279299290717	[5]	[5,6]	2	hSpCas9	positive selection	3745480
21298865	21298888	17	+	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	TCTTTCTCCACAGACCCCCCCGG	MAP2K3	ENSG00000034152	0.2894463508889021	[4]	[5,4]	8	hSpCas9	positive selection	3745481
21300592	21300615	17	-	26780180	A375	resistance to vemurafenib (Avana lentiCRISPRv2)	CTACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-0.08180236537043131	[4]	[4,3]	-1	hSpCas9	positive selection	3745482
21300957	21300980	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACACTGTCACCTTCTACGGGG	MAP2K3	ENSG00000034152	0.24734753792499975	[5]	[5,5]	6	hSpCas9	positive selection	3854084
21300972	21300995	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACGGGGCACTATTCAGAGAGG	MAP2K3	ENSG00000034152	-0.21410273667711543	[5]	[4,2]	-3	hSpCas9	positive selection	3854085
21302180	21302203	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTTCCGGTAGAACTTGTCCAAGG	MAP2K3	ENSG00000034152	-0.5364145801921334	[5]	[2,2]	-6	hSpCas9	positive selection	3854086
21300924	21300947	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CCTGGACATCAACATGCGCACGG	MAP2K3	ENSG00000034152	0.21028301826380308	[5]	[4,5]	5	hSpCas9	positive selection	3854087
21298865	21298888	17	+	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	TCTTTCTCCACAGACCCCCCCGG	MAP2K3	ENSG00000034152	0.26654904753646547	[6]	[6,6]	7	hSpCas9	positive selection	3854088
21300592	21300615	17	-	26780180	A375	resistance to vemurafenib (Avana lentiGuide)	CTACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.14915418732301822	[5]	[4,5]	3	hSpCas9	positive selection	3854089
21302187	21302210	17	+	26780180	A375	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	2.08582901318626	[]	[]	9	hSpCas9	negative selection	3959598
21300924	21300947	17	-	26780180	A375	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.973239975443298	[]	[]	4	hSpCas9	negative selection	3959599
21304516	21304539	17	-	26780180	A375	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.76282156692321	[]	[]	3	hSpCas9	negative selection	3959600
21302163	21302186	17	+	26780180	A375	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.926018686572036	[]	[]	4	hSpCas9	negative selection	3959601
21300968	21300991	17	-	26780180	A375	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	1.70267165355255	[]	[]	9	hSpCas9	negative selection	3959602
21302187	21302210	17	+	26780180	HT29	viability (GeCKOv2 library)	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	1.18491162389219	[]	[]	6	hSpCas9	negative selection	4067564
21300924	21300947	17	-	26780180	HT29	viability (GeCKOv2 library)	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	1.40143999884077	[]	[]	7	hSpCas9	negative selection	4067565
21304516	21304539	17	-	26780180	HT29	viability (GeCKOv2 library)	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	1.17242096447901	[]	[]	5	hSpCas9	negative selection	4067566
21302163	21302186	17	+	26780180	HT29	viability (GeCKOv2 library)	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	1.92179462117642	[]	[]	9	hSpCas9	negative selection	4067567
21300968	21300991	17	-	26780180	HT29	viability (GeCKOv2 library)	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	1.97805545305247	[]	[]	9	hSpCas9	negative selection	4067568
21302187	21302210	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.0016264728906379283	[4]	[2,2]	0	hSpCas9	positive selection	4150466
21300924	21300947	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiCRISPRv1)	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.2429058387345039	[4]	[3,3]	6	hSpCas9	positive selection	4150467
21302187	21302210	17	+	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	0.03395037157362746	[2]	[3,0,0,0]	0	hSpCas9	positive selection	4214488
21300924	21300947	17	-	26780180	A375	resistance to vemurafenib (GeCKOv1 lentiGuide)	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	1.1911570622463339	[4]	[4,4,4,4]	8	hSpCas9	positive selection	4214489
21304516	21304539	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.10399225847123371	[3]	[2,1]	-2	hSpCas9	positive selection	4281804
21300968	21300991	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.26005979970637483	[3]	[1,1]	-5	hSpCas9	positive selection	4281806
21300924	21300947	17	-	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.5587484172355606	[2]	[1,0]	-8	hSpCas9	positive selection	4346062
21302187	21302210	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.030246821358003162	[3]	[2,2]	0	hSpCas9	positive selection	4346063
21302163	21302186	17	+	26780180	A375	resistance to vemurafenib (GeCKOv2 lentiGuide)	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.010674577730337781	[3]	[2,1]	0	hSpCas9	positive selection	4346064
21300592	21300614	17	-	27760321	OCIAML3	viability	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-0.00971572858130576	[828,733]	[645,553]	0	hSpCas9	negative selection	4416550
21300880	21300902	17	+	27760321	OCIAML3	viability	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	-0.8727012697782331	[640,568]	[224,300]	-7	hSpCas9	negative selection	4416551
21300968	21300990	17	-	27760321	OCIAML3	viability	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.443870175844759	[580,452]	[289,301]	-4	hSpCas9	negative selection	4416552
21303177	21303199	17	+	27760321	OCIAML3	viability	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	-0.011557175774091322	[667,616]	[425,592]	0	hSpCas9	negative selection	4416553
21304438	21304460	17	-	27760321	OCIAML3	viability	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	1.0489578550228211	[35,30]	[60,44]	9	hSpCas9	negative selection	4416554
21300592	21300614	17	-	27760321	OCIAML2	viability	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.2043145819075558	[828,733]	[705,754]	2	hSpCas9	negative selection	4500013
21300880	21300902	17	+	27760321	OCIAML2	viability	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.07148389059031801	[640,568]	[487,546]	0	hSpCas9	negative selection	4500014
21300968	21300990	17	-	27760321	OCIAML2	viability	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.24893216165131646	[580,452]	[292,423]	-3	hSpCas9	negative selection	4500015
21303177	21303199	17	+	27760321	OCIAML2	viability	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	-0.14789591008764996	[667,616]	[387,575]	-2	hSpCas9	negative selection	4500016
21304438	21304460	17	-	27760321	OCIAML2	viability	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	-0.5611471856803956	[35,30]	[13,23]	-6	hSpCas9	negative selection	4500017
21300592	21300614	17	-	27760321	MV411	viability	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.6822134414230063	[828,733]	[947,642]	5	hSpCas9	negative selection	4583476
21300880	21300902	17	+	27760321	MV411	viability	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	-0.3923783591480578	[640,568]	[162,514]	-3	hSpCas9	negative selection	4583477
21300968	21300990	17	-	27760321	MV411	viability	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	0.31297849780873543	[580,452]	[310,585]	2	hSpCas9	negative selection	4583478
21303177	21303199	17	+	27760321	MV411	viability	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	0.2835658984293308	[667,616]	[141,1077]	2	hSpCas9	negative selection	4583479
21304438	21304460	17	-	27760321	MV411	viability	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	1.6034272228125315	[35,30]	[46,96]	9	hSpCas9	negative selection	4583480
21300592	21300614	17	-	27760321	HL60	viability	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.45987876861442856	[828,733]	[861,891]	5	hSpCas9	negative selection	4666939
21300880	21300902	17	+	27760321	HL60	viability	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.20305381460876626	[640,568]	[517,620]	2	hSpCas9	negative selection	4666940
21300968	21300990	17	-	27760321	HL60	viability	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	0.4767315880786911	[580,452]	[588,577]	6	hSpCas9	negative selection	4666941
21303177	21303199	17	+	27760321	HL60	viability	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	-0.34736329171273095	[667,616]	[380,445]	-4	hSpCas9	negative selection	4666942
21304438	21304460	17	-	27760321	HL60	viability	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	1.4900113317804364	[35,30]	[64,88]	9	hSpCas9	negative selection	4666943
21300592	21300614	17	-	27760321	HT1080	viability	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.15576493432022487	[733,572]	[300,277]	0	hSpCas9	negative selection	4750402
21300880	21300902	17	+	27760321	HT1080	viability	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	-0.7106004190857182	[568,443]	[118,127]	-3	hSpCas9	negative selection	4750403
21300968	21300990	17	-	27760321	HT1080	viability	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.7765410119373071	[452,353]	[79,108]	-3	hSpCas9	negative selection	4750404
21303177	21303199	17	+	27760321	HT1080	viability	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	0.5381184438051058	[616,481]	[188,458]	3	hSpCas9	negative selection	4750405
21304438	21304460	17	-	27760321	HT1080	viability	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	-1.6929169929110621	[30,23]	[0,5]	-6	hSpCas9	negative selection	4750406
21300592	21300614	17	-	27760321	HT29	viability after 7 days	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.43541499010737195	[733,572]	[1675,829,982]	6	hSpCas9	negative selection	4833865
21300880	21300902	17	+	27760321	HT29	viability after 7 days	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.3902700832183052	[568,443]	[1068,858,667]	6	hSpCas9	negative selection	4833866
21300968	21300990	17	-	27760321	HT29	viability after 7 days	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	0.27492150639536017	[452,353]	[912,477,534]	4	hSpCas9	negative selection	4833867
21303177	21303199	17	+	27760321	HT29	viability after 7 days	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	0.1702201111408711	[616,481]	[1026,817,578]	2	hSpCas9	negative selection	4833868
21304438	21304460	17	-	27760321	HT29	viability after 7 days	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	0.0037436027170296704	[30,23]	[34,29,40]	0	hSpCas9	negative selection	4833869
21300592	21300614	17	-	27760321	HT29	viability after 25 days	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-0.28193512041285196	[733,572]	[510,579,773]	-3	hSpCas9	negative selection	4917328
21300880	21300902	17	+	27760321	HT29	viability after 25 days	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.12379454788119332	[568,443]	[482,643,789]	1	hSpCas9	negative selection	4917329
21300968	21300990	17	-	27760321	HT29	viability after 25 days	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.2696678342178639	[452,353]	[451,356,327]	-3	hSpCas9	negative selection	4917330
21303177	21303199	17	+	27760321	HT29	viability after 25 days	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	-0.08827427996669157	[616,481]	[635,476,662]	-1	hSpCas9	negative selection	4917331
21304438	21304460	17	-	27760321	HT29	viability after 25 days	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	0.7221449334069785	[30,23]	[35,88,28]	7	hSpCas9	negative selection	4917332
21300592	21300614	17	-	27760321	HT29	viability after 22 days	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-0.4567538705009864	[733,572]	[360,692,602]	-4	hSpCas9	negative selection	5000791
21300880	21300902	17	+	27760321	HT29	viability after 22 days	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	-0.13290730287674124	[568,443]	[611,335,652]	-1	hSpCas9	negative selection	5000792
21300968	21300990	17	-	27760321	HT29	viability after 22 days	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.3393005354267742	[452,353]	[263,582,260]	-3	hSpCas9	negative selection	5000793
21303177	21303199	17	+	27760321	HT29	viability after 22 days	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	-0.22012175298758124	[616,481]	[504,297,836]	-2	hSpCas9	negative selection	5000794
21304438	21304460	17	-	27760321	HT29	viability after 22 days	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	0.32311880186028397	[30,23]	[26,10,81]	3	hSpCas9	negative selection	5000795
21300592	21300614	17	-	27760321	HT29	viability after 19 days	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-0.6032205535151592	[733,572]	[366,560,532]	-5	hSpCas9	negative selection	5084254
21300880	21300902	17	+	27760321	HT29	viability after 19 days	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.1947645878931344	[568,443]	[588,439,940]	1	hSpCas9	negative selection	5084255
21300968	21300990	17	-	27760321	HT29	viability after 19 days	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	0.3035766549413018	[452,353]	[468,367,849]	3	hSpCas9	negative selection	5084256
21303177	21303199	17	+	27760321	HT29	viability after 19 days	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	-0.18180679526692362	[616,481]	[740,428,512]	-2	hSpCas9	negative selection	5084257
21304438	21304460	17	-	27760321	HT29	viability after 19 days	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	0.5481575643210763	[30,23]	[87,27,26]	5	hSpCas9	negative selection	5084258
21300592	21300614	17	-	27760321	HT29	viability after 16 days	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-0.05620545366875618	[733,572]	[636,636,830]	0	hSpCas9	negative selection	5167717
21300880	21300902	17	+	27760321	HT29	viability after 16 days	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.19611308737055405	[568,443]	[789,370,806]	2	hSpCas9	negative selection	5167718
21300968	21300990	17	-	27760321	HT29	viability after 16 days	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.03768830800408762	[452,353]	[641,344,353]	0	hSpCas9	negative selection	5167719
21303177	21303199	17	+	27760321	HT29	viability after 16 days	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	0.2564309555785299	[616,481]	[896,637,685]	3	hSpCas9	negative selection	5167720
21304438	21304460	17	-	27760321	HT29	viability after 16 days	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	1.0341804321526782	[30,23]	[81,13,95]	9	hSpCas9	negative selection	5167721
21300592	21300614	17	-	27760321	HT29	viability after 13 days	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.031108912900203456	[733,572]	[680,781,855]	0	hSpCas9	negative selection	5251180
21300880	21300902	17	+	27760321	HT29	viability after 13 days	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.3729400061307992	[568,443]	[1014,556,712]	5	hSpCas9	negative selection	5251181
21300968	21300990	17	-	27760321	HT29	viability after 13 days	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.2789269915553545	[452,353]	[494,272,388]	-3	hSpCas9	negative selection	5251182
21303177	21303199	17	+	27760321	HT29	viability after 13 days	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	0.25429168930605506	[616,481]	[722,590,954]	3	hSpCas9	negative selection	5251183
21304438	21304460	17	-	27760321	HT29	viability after 13 days	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	1.126431918699013	[30,23]	[40,99,67]	9	hSpCas9	negative selection	5251184
21300592	21300614	17	-	27760321	HT29	viability after 10 days	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	0.18702891903232277	[733,572]	[946,990,851]	2	hSpCas9	negative selection	5334643
21300880	21300902	17	+	27760321	HT29	viability after 10 days	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	0.3792506301038188	[568,443]	[756,762,942]	5	hSpCas9	negative selection	5334644
21300968	21300990	17	-	27760321	HT29	viability after 10 days	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	0.07689264067420834	[452,353]	[670,505,418]	1	hSpCas9	negative selection	5334645
21303177	21303199	17	+	27760321	HT29	viability after 10 days	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	0.16632061101501894	[616,481]	[750,602,946]	2	hSpCas9	negative selection	5334646
21304438	21304460	17	-	27760321	HT29	viability after 10 days	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	0.9122043477063051	[30,23]	[45,37,107]	9	hSpCas9	negative selection	5334647
21300592	21300614	17	-	27760321	MOLM13	viability	TACCACCCCATAGGCTCCACGG	MAP2K3	ENSG00000034152	-0.3607605360155483	[828,733]	[338,345]	-2	hSpCas9	negative selection	5418106
21300880	21300902	17	+	27760321	MOLM13	viability	CGGGCCACCGTGAACTCACAGG	MAP2K3	ENSG00000034152	-0.7534583826272223	[640,568]	[300,117]	-5	hSpCas9	negative selection	5418107
21300968	21300990	17	-	27760321	MOLM13	viability	CTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	0.9667442530801238	[580,452]	[758,401]	7	hSpCas9	negative selection	5418108
21303177	21303199	17	+	27760321	MOLM13	viability	CGCCAGATCGTGCGGGCCCTGG	MAP2K3	ENSG00000034152	-0.8193820110352357	[667,616]	[118,278]	-5	hSpCas9	negative selection	5418109
21304438	21304460	17	-	27760321	MOLM13	viability	TCCTTGTTGATAAGGACATTGG	MAP2K3	ENSG00000034152	2.120173016712787	[35,30]	[28,126]	9	hSpCas9	negative selection	5418110
21284701	21284724	17	+	27661255	K562	viability	GGCGCTGCCCAGTCTGTCTCCGG	MAP2K3	ENSG00000034152	-0.10141664589779298	[157,247]	[143,154]	-4	dCas9-KRAB	negative selection	5492057
21284952	21284975	17	+	27661255	K562	viability	GCATGCCCCAGTCCAAAGGTAGG	MAP2K3	ENSG00000034152	-0.25026124806851446	[472,430]	[309,298]	-6	dCas9-KRAB	negative selection	5492058
21284708	21284731	17	-	27661255	K562	viability	GGCGGCGCCGGAGACAGACTGGG	MAP2K3	ENSG00000034152	-0.24523018452675172	[677,852]	[570,464]	-6	dCas9-KRAB	negative selection	5492059
21284759	21284782	17	-	27661255	K562	viability	GACTGCGGCGAGGACTGCGGCGG	MAP2K3	ENSG00000034152	-0.4630963697146874	[1238,1195]	[780,641]	-7	dCas9-KRAB	negative selection	5492060
21284878	21284901	17	-	27661255	K562	viability	GGCGGTGGAGACTAATCTAGAGG	MAP2K3	ENSG00000034152	-0.40248770541154466	[758,602]	[463,369]	-7	dCas9-KRAB	negative selection	5492061
21304516	21304539	17	-	27260156	BXPC3	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.01827287024004956	[502]	[473,490,502,624]	0	hSpCas9	negative selection	5554264
21300968	21300991	17	-	27260156	BXPC3	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.03489620885979766	[546]	[484,516,621,624]	-1	hSpCas9	negative selection	5554266
21300924	21300947	17	-	27260156	BXPC3	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.007548320062264802	[237]	[282,254,198,245]	0	hSpCas9	negative selection	5618522
21302187	21302210	17	+	27260156	BXPC3	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.1921105633453859	[968]	[733,901,1016,908]	-4	hSpCas9	negative selection	5618523
21302163	21302186	17	+	27260156	BXPC3	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.04674559682946394	[541]	[402,511,512,812]	-1	hSpCas9	negative selection	5618524
21304516	21304539	17	-	27260156	A673	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.04910632089048715	[502]	[702,420,662,562]	-1	hSpCas9	negative selection	5675515
21300968	21300991	17	-	27260156	A673	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.201015682702084	[546]	[706,440,529,628]	-5	hSpCas9	negative selection	5675517
21300924	21300947	17	-	27260156	A673	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.24018483428416415	[237]	[335,182,275,180]	-5	hSpCas9	negative selection	5739773
21302187	21302210	17	+	27260156	A673	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.36767595458233104	[968]	[963,827,834,992]	-7	hSpCas9	negative selection	5739774
21302163	21302186	17	+	27260156	A673	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.001173490966159485	[541]	[797,519,615,692]	0	hSpCas9	negative selection	5739775
21304516	21304539	17	-	27260156	A375	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.5016208842990288	[502]	[465,440,439,325]	-6	hSpCas9	negative selection	5796766
21300968	21300991	17	-	27260156	A375	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.2745310927688104	[546]	[518,605,565,440]	-4	hSpCas9	negative selection	5796768
21300924	21300947	17	-	27260156	A375	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.14374992535586784	[237]	[323,368,263,281]	2	hSpCas9	negative selection	5861024
21302187	21302210	17	+	27260156	A375	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.4153971946543493	[968]	[877,996,835,716]	-5	hSpCas9	negative selection	5861025
21302163	21302186	17	+	27260156	A375	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.3003985475695511	[541]	[538,485,626,410]	-4	hSpCas9	negative selection	5861026
21304516	21304539	17	-	27260156	COLO741	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.0013580564578670323	[502]	[640,770,521]	0	hSpCas9	negative selection	5918017
21300968	21300991	17	-	27260156	COLO741	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.23281859934415944	[546]	[485,763,528]	-5	hSpCas9	negative selection	5918019
21300924	21300947	17	-	27260156	COLO741	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.15075277919094787	[237]	[437,309,276]	3	hSpCas9	negative selection	5982275
21302187	21302210	17	+	27260156	COLO741	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.2307875977075855	[968]	[1154,1084,939]	-5	hSpCas9	negative selection	5982276
21302163	21302186	17	+	27260156	COLO741	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.22658653254290506	[541]	[651,559,568]	-5	hSpCas9	negative selection	5982277
21304516	21304539	17	-	27260156	CAL120	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.08544445962763382	[502]	[836,506,464]	-1	hSpCas9	negative selection	6039268
21300968	21300991	17	-	27260156	CAL120	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.448607867459829	[546]	[487,536,469]	-6	hSpCas9	negative selection	6039270
21300924	21300947	17	-	27260156	CAL120	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.1675088201371311	[237]	[282,470,237]	2	hSpCas9	negative selection	6103526
21302187	21302210	17	+	27260156	CAL120	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.5937050480164379	[968]	[1101,635,705]	-7	hSpCas9	negative selection	6103527
21302163	21302186	17	+	27260156	CAL120	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.05144183094219168	[541]	[557,658,719]	0	hSpCas9	negative selection	6103528
21304516	21304539	17	-	27260156	CADOES1	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.6111103732573823	[502]	[256,270,419,275]	-8	hSpCas9	negative selection	6160519
21300968	21300991	17	-	27260156	CADOES1	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.31756017194521224	[546]	[383,283,369,601]	-5	hSpCas9	negative selection	6160521
21300924	21300947	17	-	27260156	CADOES1	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.14052161825858056	[237]	[284,279,242,164]	2	hSpCas9	negative selection	6224777
21302187	21302210	17	+	27260156	CADOES1	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.4190267585709714	[968]	[571,588,994,534]	-6	hSpCas9	negative selection	6224778
21302163	21302186	17	+	27260156	CADOES1	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.13820806603842606	[541]	[455,605,299,470]	-2	hSpCas9	negative selection	6224779
21304516	21304539	17	-	27260156	EWS502	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.16942331312470227	[502]	[484,398,937,598]	3	hSpCas9	negative selection	6281770
21300968	21300991	17	-	27260156	EWS502	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.3083109249616579	[546]	[407,542,386,539]	-5	hSpCas9	negative selection	6281772
21300924	21300947	17	-	27260156	EWS502	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.3260263806532028	[237]	[345,194,397,326]	6	hSpCas9	negative selection	6346028
21302187	21302210	17	+	27260156	EWS502	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.3556524625644888	[968]	[736,817,844,813]	-6	hSpCas9	negative selection	6346029
21302163	21302186	17	+	27260156	EWS502	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.37469556378847596	[541]	[657,637,840,861]	6	hSpCas9	negative selection	6346030
21304516	21304539	17	-	27260156	EW8	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.22223234977424278	[502]	[445,319,279,372]	-4	hSpCas9	negative selection	6403021
21300968	21300991	17	-	27260156	EW8	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.32909630327298117	[546]	[486,316,366,251]	-6	hSpCas9	negative selection	6403023
21300924	21300947	17	-	27260156	EW8	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.13211347432864695	[237]	[136,204,117,391]	2	hSpCas9	negative selection	6467279
21302187	21302210	17	+	27260156	EW8	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.21063153477085683	[968]	[716,774,591,647]	-4	hSpCas9	negative selection	6467280
21302163	21302186	17	+	27260156	EW8	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.0372235204593509	[541]	[525,443,404,350]	0	hSpCas9	negative selection	6467281
21304516	21304539	17	-	27260156	CORL105	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.011761957855098815	[502]	[548,516,718,608]	0	hSpCas9	negative selection	6524272
21300968	21300991	17	-	27260156	CORL105	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.10597644213782698	[546]	[700,541,627,518]	-2	hSpCas9	negative selection	6524274
21300924	21300947	17	-	27260156	CORL105	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.011203426296889862	[237]	[336,212,378,212]	0	hSpCas9	negative selection	6588530
21302187	21302210	17	+	27260156	CORL105	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.29217158694409473	[968]	[1032,827,913,933]	-5	hSpCas9	negative selection	6588531
21302163	21302186	17	+	27260156	CORL105	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.11794544400602722	[541]	[567,542,755,498]	-2	hSpCas9	negative selection	6588532
21304516	21304539	17	-	27260156	HS294T	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.0634064598784994	[502]	[314,123,151,214]	0	hSpCas9	negative selection	6645523
21300968	21300991	17	-	27260156	HS294T	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.08999694847973469	[546]	[244,213,171,149]	-1	hSpCas9	negative selection	6645525
21300924	21300947	17	-	27260156	HS294T	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.6739644396339892	[237]	[86,324,74,89]	8	hSpCas9	negative selection	6709781
21302187	21302210	17	+	27260156	HS294T	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.9850158326914588	[968]	[149,197,182,236]	-8	hSpCas9	negative selection	6709782
21302163	21302186	17	+	27260156	HS294T	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.1363409328010144	[541]	[245,166,288,216]	1	hSpCas9	negative selection	6709783
21304516	21304539	17	-	27260156	HCC44	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.18121413666346842	[502]	[591,308,610,543]	-3	hSpCas9	negative selection	6766774
21300968	21300991	17	-	27260156	HCC44	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.42871672729065846	[546]	[607,449,440,350]	-6	hSpCas9	negative selection	6766776
21300924	21300947	17	-	27260156	HCC44	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.11814321803936711	[237]	[238,184,486,298]	1	hSpCas9	negative selection	6831032
21302187	21302210	17	+	27260156	HCC44	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.8255590030215048	[968]	[496,553,749,685]	-8	hSpCas9	negative selection	6831033
21302163	21302186	17	+	27260156	HCC44	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.020663233690181554	[541]	[553,625,898,449]	0	hSpCas9	negative selection	6831034
21304516	21304539	17	-	27260156	G402	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.9856679732751725	[502]	[250,362,178,433]	-8	hSpCas9	negative selection	6888025
21300968	21300991	17	-	27260156	G402	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.7211151096969999	[546]	[550,165,307,590]	-7	hSpCas9	negative selection	6888027
21300924	21300947	17	-	27260156	G402	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.29499911886135544	[237]	[294,327,107,228]	-4	hSpCas9	negative selection	6952283
21302187	21302210	17	+	27260156	G402	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.9870064356355093	[968]	[529,761,625,471]	-8	hSpCas9	negative selection	6952284
21302163	21302186	17	+	27260156	G402	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-1.2309792911809532	[541]	[441,88,200,399]	-8	hSpCas9	negative selection	6952285
21304516	21304539	17	-	27260156	L33	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.1702856871689566	[502]	[510,228,435,502]	4	hSpCas9	negative selection	7009276
21300968	21300991	17	-	27260156	L33	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.3958577495606389	[546]	[414,202,216,406]	-7	hSpCas9	negative selection	7009278
21300924	21300947	17	-	27260156	L33	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.5165000106980775	[237]	[153,64,81,221]	-8	hSpCas9	negative selection	7073534
21302187	21302210	17	+	27260156	L33	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.40762953824822945	[968]	[771,366,361,676]	-7	hSpCas9	negative selection	7073535
21302163	21302186	17	+	27260156	L33	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.054887280349473044	[541]	[669,204,289,451]	-1	hSpCas9	negative selection	7073536
21304516	21304539	17	-	27260156	K562	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.5491600525928916	[502]	[321,303,446,163]	-6	hSpCas9	negative selection	7130527
21300968	21300991	17	-	27260156	K562	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.45125410936286114	[546]	[402,642,114,284]	-5	hSpCas9	negative selection	7130529
21300924	21300947	17	-	27260156	K562	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.6455215455119483	[237]	[182,158,98,106]	-6	hSpCas9	negative selection	7194785
21302187	21302210	17	+	27260156	K562	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-1.1372913886158247	[968]	[421,447,253,437]	-8	hSpCas9	negative selection	7194786
21302163	21302186	17	+	27260156	K562	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.03215942782112355	[541]	[610,237,661,454]	0	hSpCas9	negative selection	7194787
21304516	21304539	17	-	27260156	HT29	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.22800905534539367	[502]	[628,513,480,473]	-4	hSpCas9	negative selection	7251778
21300968	21300991	17	-	27260156	HT29	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.2889661074345858	[546]	[593,801,348,463]	-5	hSpCas9	negative selection	7251780
21300924	21300947	17	-	27260156	HT29	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.2596464744740681	[237]	[196,371,236,174]	-5	hSpCas9	negative selection	7316036
21302187	21302210	17	+	27260156	HT29	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.077176989313547	[968]	[1112,1238,906,1198]	-2	hSpCas9	negative selection	7316037
21302163	21302186	17	+	27260156	HT29	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.004530468977664459	[541]	[534,825,608,671]	0	hSpCas9	negative selection	7316038
21304516	21304539	17	-	27260156	MHHES1	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.022427608344932223	[502]	[575,656,420,571]	0	hSpCas9	negative selection	7373029
21300968	21300991	17	-	27260156	MHHES1	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.09343315485328088	[546]	[695,726,636,325]	-2	hSpCas9	negative selection	7373031
21300924	21300947	17	-	27260156	MHHES1	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.020038611134574724	[237]	[257,320,268,242]	0	hSpCas9	negative selection	7437287
21302187	21302210	17	+	27260156	MHHES1	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.09799782573806681	[968]	[1286,1280,798,797]	-2	hSpCas9	negative selection	7437288
21302163	21302186	17	+	27260156	MHHES1	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.1725531022594854	[541]	[658,590,410,516]	-3	hSpCas9	negative selection	7437289
21304516	21304539	17	-	27260156	MEWO	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.3586045460795773	[502]	[330,366,395]	-7	hSpCas9	negative selection	7494280
21300968	21300991	17	-	27260156	MEWO	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.088294420936816	[546]	[435,525,472]	-2	hSpCas9	negative selection	7494282
21300924	21300947	17	-	27260156	MEWO	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.06064617015810869	[237]	[258,266,122]	-1	hSpCas9	negative selection	7558538
21302187	21302210	17	+	27260156	MEWO	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	0.00307931569591946	[968]	[1022,799,924]	0	hSpCas9	negative selection	7558539
21302163	21302186	17	+	27260156	MEWO	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.10262983614509111	[541]	[382,547,467]	-2	hSpCas9	negative selection	7558540
21304516	21304539	17	-	27260156	LNCAPCLONEFGC	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.49461494640092746	[502]	[225,334,400,343]	-6	hSpCas9	negative selection	7615531
21300968	21300991	17	-	27260156	LNCAPCLONEFGC	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.4767109834191813	[546]	[264,243,468,471]	-6	hSpCas9	negative selection	7615533
21300924	21300947	17	-	27260156	LNCAPCLONEFGC	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.016831258654911863	[237]	[198,169,358,148]	0	hSpCas9	negative selection	7679789
21302187	21302210	17	+	27260156	LNCAPCLONEFGC	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.3109307882424527	[968]	[703,653,683,787]	-5	hSpCas9	negative selection	7679790
21302163	21302186	17	+	27260156	LNCAPCLONEFGC	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.0047047961426552876	[541]	[479,559,473,448]	0	hSpCas9	negative selection	7679791
21304516	21304539	17	-	27260156	PANC0327	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.09831717652821326	[502]	[481,422,406,361]	-1	hSpCas9	negative selection	7736782
21300968	21300991	17	-	27260156	PANC0327	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.05774944208705349	[546]	[486,528,508,335]	-1	hSpCas9	negative selection	7736784
21300924	21300947	17	-	27260156	PANC0327	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.14262996331554978	[237]	[197,190,235,310]	2	hSpCas9	negative selection	7801040
21302187	21302210	17	+	27260156	PANC0327	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.7166309952059975	[968]	[360,453,724,550]	-7	hSpCas9	negative selection	7801041
21302163	21302186	17	+	27260156	PANC0327	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.04338840011919043	[541]	[510,495,602,375]	0	hSpCas9	negative selection	7801042
21304516	21304539	17	-	27260156	NCIH2009	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.28277575169523766	[502]	[823,508,448]	-4	hSpCas9	negative selection	7858033
21300968	21300991	17	-	27260156	NCIH2009	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.5000627180823288	[546]	[681,496,469]	-6	hSpCas9	negative selection	7858035
21300924	21300947	17	-	27260156	NCIH2009	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.1639386757112079	[237]	[486,295,357]	2	hSpCas9	negative selection	7922291
21302187	21302210	17	+	27260156	NCIH2009	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.9401460718941642	[968]	[857,689,597]	-8	hSpCas9	negative selection	7922292
21302163	21302186	17	+	27260156	NCIH2009	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.1576995845783693	[541]	[708,642,689]	-2	hSpCas9	negative selection	7922293
21304516	21304539	17	-	27260156	NCIH1373	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.0760111080990548	[502]	[714,556,325,214]	0	hSpCas9	negative selection	7979284
21300968	21300991	17	-	27260156	NCIH1373	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.3336851028668499	[546]	[1005,354,238,115]	-3	hSpCas9	negative selection	7979286
21300924	21300947	17	-	27260156	NCIH1373	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.5323077909663665	[237]	[413,386,314,113]	5	hSpCas9	negative selection	8043542
21302187	21302210	17	+	27260156	NCIH1373	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.1173402324145082	[968]	[817,1227,1107,203]	-1	hSpCas9	negative selection	8043543
21302163	21302186	17	+	27260156	NCIH1373	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.4540679784084624	[541]	[482,382,286,169]	-4	hSpCas9	negative selection	8043544
21304516	21304539	17	-	27260156	PATU8902	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-1.3989803926765345	[502]	[424,207,250,165]	-8	hSpCas9	negative selection	8100535
21300968	21300991	17	-	27260156	PATU8902	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.694923524798072	[546]	[373,679,335,532]	-6	hSpCas9	negative selection	8100537
21300924	21300947	17	-	27260156	PATU8902	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.33071516192728256	[237]	[543,97,180,243]	-3	hSpCas9	negative selection	8164793
21302187	21302210	17	+	27260156	PATU8902	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.8980487288036172	[968]	[880,799,448,844]	-7	hSpCas9	negative selection	8164794
21302163	21302186	17	+	27260156	PATU8902	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-1.4220727111151212	[541]	[195,500,209,231]	-8	hSpCas9	negative selection	8164795
21304516	21304539	17	-	27260156	PANC1	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.07489321387978794	[502]	[379,340,397,487]	-1	hSpCas9	negative selection	8221786
21300968	21300991	17	-	27260156	PANC1	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.20717488127299497	[546]	[334,369,471,433]	-3	hSpCas9	negative selection	8221788
21300924	21300947	17	-	27260156	PANC1	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.07565501257626372	[237]	[124,167,280,267]	1	hSpCas9	negative selection	8286044
21302187	21302210	17	+	27260156	PANC1	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.6554561182105572	[968]	[477,766,468,452]	-7	hSpCas9	negative selection	8286045
21302163	21302186	17	+	27260156	PANC1	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.15010734391411243	[541]	[518,631,250,324]	-2	hSpCas9	negative selection	8286046
21304516	21304539	17	-	27260156	PANC0813	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.13005998464690954	[502]	[659,587,438,884]	2	hSpCas9	negative selection	8343037
21300968	21300991	17	-	27260156	PANC0813	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.11337991913729453	[546]	[710,508,594,571]	-2	hSpCas9	negative selection	8343039
21300924	21300947	17	-	27260156	PANC0813	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.45737084130965555	[237]	[219,258,179,158]	-6	hSpCas9	negative selection	8407295
21302187	21302210	17	+	27260156	PANC0813	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.31282611642018254	[968]	[984,988,907,794]	-5	hSpCas9	negative selection	8407296
21302163	21302186	17	+	27260156	PANC0813	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.028067954946591867	[541]	[836,684,510,582]	0	hSpCas9	negative selection	8407297
21304516	21304539	17	-	27260156	RDES	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.21597160596495546	[502]	[607,683,697,691]	3	hSpCas9	negative selection	8464288
21300968	21300991	17	-	27260156	RDES	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.17255445124269292	[546]	[515,518,666,523]	-3	hSpCas9	negative selection	8464290
21300924	21300947	17	-	27260156	RDES	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.11694181505147805	[237]	[144,339,363,373]	2	hSpCas9	negative selection	8528546
21302187	21302210	17	+	27260156	RDES	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.13232196045315991	[968]	[992,974,1033,1043]	-2	hSpCas9	negative selection	8528547
21302163	21302186	17	+	27260156	RDES	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.07175374945309715	[541]	[551,588,779,722]	1	hSpCas9	negative selection	8528548
21304516	21304539	17	-	27260156	PC3	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.1256762293510611	[502]	[418,427,996,517]	3	hSpCas9	negative selection	8585539
21300968	21300991	17	-	27260156	PC3	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.12265173818525352	[546]	[478,365,460,632]	-3	hSpCas9	negative selection	8585541
21300924	21300947	17	-	27260156	PC3	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.022863859682003107	[237]	[128,187,760,115]	0	hSpCas9	negative selection	8649797
21302187	21302210	17	+	27260156	PC3	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.24264025928239186	[968]	[628,486,1597,865]	-5	hSpCas9	negative selection	8649798
21302163	21302186	17	+	27260156	PC3	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.10920826228806613	[541]	[509,383,874,645]	2	hSpCas9	negative selection	8649799
21304516	21304539	17	-	27260156	PATU8988T	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-1.1094728936773193	[502]	[163,293,218,230]	-9	hSpCas9	negative selection	8706790
21300968	21300991	17	-	27260156	PATU8988T	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-1.0884189959758632	[546]	[386,275,175,150]	-9	hSpCas9	negative selection	8706792
21300924	21300947	17	-	27260156	PATU8988T	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.2194023806404397	[237]	[243,131,217,188]	-4	hSpCas9	negative selection	8771048
21302187	21302210	17	+	27260156	PATU8988T	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.6511136422628894	[968]	[357,765,577,707]	-7	hSpCas9	negative selection	8771049
21302163	21302186	17	+	27260156	PATU8988T	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.0016821518843466443	[541]	[940,236,316,582]	0	hSpCas9	negative selection	8771050
21304516	21304539	17	-	27260156	T47D	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.321732854777655	[502]	[492,437,475,470]	-6	hSpCas9	negative selection	8828041
21300968	21300991	17	-	27260156	T47D	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.1755509543631346	[546]	[525,604,580,539]	-4	hSpCas9	negative selection	8828043
21300924	21300947	17	-	27260156	T47D	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.38888635671153393	[237]	[324,395,364,362]	7	hSpCas9	negative selection	8892299
21302187	21302210	17	+	27260156	T47D	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.3856563118172006	[968]	[924,916,756,853]	-7	hSpCas9	negative selection	8892300
21302163	21302186	17	+	27260156	T47D	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.019863777602734778	[541]	[606,575,584,730]	0	hSpCas9	negative selection	8892301
21304516	21304539	17	-	27260156	SU8686	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.26503312376271476	[502]	[556,550,589,725]	4	hSpCas9	negative selection	8949292
21300968	21300991	17	-	27260156	SU8686	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.20152735649952183	[546]	[472,481,465,457]	-4	hSpCas9	negative selection	8949294
21300924	21300947	17	-	27260156	SU8686	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.08196571089570337	[237]	[135,246,276,370]	1	hSpCas9	negative selection	9013550
21302187	21302210	17	+	27260156	SU8686	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.3719467909902876	[968]	[670,657,741,944]	-6	hSpCas9	negative selection	9013551
21302163	21302186	17	+	27260156	SU8686	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	0.04975859166028834	[541]	[542,485,442,794]	0	hSpCas9	negative selection	9013552
21304516	21304539	17	-	27260156	SKES1	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.3072649202485899	[502]	[419,475,397,341]	-6	hSpCas9	negative selection	9070543
21300968	21300991	17	-	27260156	SKES1	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	0.07464354134061105	[546]	[521,710,613,466]	1	hSpCas9	negative selection	9070545
21300924	21300947	17	-	27260156	SKES1	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.11625821860862406	[237]	[259,268,194,167]	-3	hSpCas9	negative selection	9134801
21302187	21302210	17	+	27260156	SKES1	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.2334982796042917	[968]	[890,877,906,640]	-5	hSpCas9	negative selection	9134802
21302163	21302186	17	+	27260156	SKES1	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.0435945192091422	[541]	[646,595,554,341]	-1	hSpCas9	negative selection	9134803
21304516	21304539	17	-	27260156	TOV112D	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.26262817412369405	[502]	[410,555,332,411]	-5	hSpCas9	negative selection	9191794
21300968	21300991	17	-	27260156	TOV112D	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.446814125795961	[546]	[383,525,356,369]	-7	hSpCas9	negative selection	9191796
21300924	21300947	17	-	27260156	TOV112D	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	-0.029077986048576587	[237]	[117,323,213,288]	0	hSpCas9	negative selection	9256052
21302187	21302210	17	+	27260156	TOV112D	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.1285302024911995	[968]	[822,1185,735,872]	-3	hSpCas9	negative selection	9256053
21302163	21302186	17	+	27260156	TOV112D	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.2444098723812152	[541]	[475,647,391,366]	-5	hSpCas9	negative selection	9256054
21304516	21304539	17	-	27260156	TC71	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	0.00377763118528629	[502]	[490,553,479,646]	0	hSpCas9	negative selection	9313045
21300968	21300991	17	-	27260156	TC71	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.2770852949562111	[546]	[448,520,465,501]	-6	hSpCas9	negative selection	9313047
21300924	21300947	17	-	27260156	TC71	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.06089756767460297	[237]	[298,276,293,187]	1	hSpCas9	negative selection	9377303
21302187	21302210	17	+	27260156	TC71	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.3076747874776198	[968]	[816,853,727,969]	-7	hSpCas9	negative selection	9377304
21302163	21302186	17	+	27260156	TC71	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.22352615362702383	[541]	[431,530,487,543]	-5	hSpCas9	negative selection	9377305
21304516	21304539	17	-	27260156	TC32	viability	GCAGCCGGCATCCATCGTCTTGG	MAP2K3	ENSG00000034152	-0.1900658523038679	[502]	[390,383,513,370]	-3	hSpCas9	negative selection	9434296
21300968	21300991	17	-	27260156	TC32	viability	TCTGAATAGTGCCCCGTAGAAGG	MAP2K3	ENSG00000034152	-0.12144533437004434	[546]	[553,387,418,512]	-2	hSpCas9	negative selection	9434298
21300924	21300947	17	-	27260156	TC32	viability	CCGTGCGCATGTTGATGTCCAGG	MAP2K3	ENSG00000034152	0.24688038029727166	[237]	[207,172,266,451]	4	hSpCas9	negative selection	9498554
21302187	21302210	17	+	27260156	TC32	viability	CAAGTTCTACCGGAAGGTGCTGG	MAP2K3	ENSG00000034152	-0.4716697273675151	[968]	[480,467,1074,736]	-7	hSpCas9	negative selection	9498555
21302163	21302186	17	+	27260156	TC32	viability	GGAGCTCATGGACACATCCTTGG	MAP2K3	ENSG00000034152	-0.04216588412685163	[541]	[412,388,773,470]	0	hSpCas9	negative selection	9498556
21284959	21284982	17	-	27869803	HPAFII	viability after 27 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.6728412649842258	[144]	[61,35,NaN]	-5	hSpCas9	negative selection	9559574
21295690	21295713	17	+	27869803	HPAFII	viability after 27 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-1.522862381034339	[159]	[43,16,NaN]	-7	hSpCas9	negative selection	9559575
21295740	21295763	17	-	27869803	HPAFII	viability after 27 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.0483420923116904	[100]	[97,18,NaN]	0	hSpCas9	negative selection	9559576
21298881	21298904	17	-	27869803	HPAFII	viability after 27 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.13834755059252407	[177]	[30,162,NaN]	1	hSpCas9	negative selection	9559577
21302181	21302204	17	+	27869803	HPAFII	viability after 27 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.8496448014975129	[195]	[108,13,NaN]	-5	hSpCas9	negative selection	9559578
21303213	21303236	17	+	27869803	HPAFII	viability after 27 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.8280338463124004	[360]	[107,105,NaN]	-5	hSpCas9	negative selection	9559579
21284959	21284982	17	-	27869803	HPAFII	viability after 15 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.1753744436382817	[144]	[302,96,NaN]	2	hSpCas9	negative selection	9642023
21295690	21295713	17	+	27869803	HPAFII	viability after 15 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-0.8882792248214284	[159]	[103,85,NaN]	-7	hSpCas9	negative selection	9642024
21295740	21295763	17	-	27869803	HPAFII	viability after 15 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.3076269021980689	[100]	[269,49,NaN]	3	hSpCas9	negative selection	9642025
21298881	21298904	17	-	27869803	HPAFII	viability after 15 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.4930143499288757	[177]	[111,366,NaN]	5	hSpCas9	negative selection	9642026
21302181	21302204	17	+	27869803	HPAFII	viability after 15 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.826846763940235	[195]	[164,89,NaN]	-7	hSpCas9	negative selection	9642027
21303213	21303236	17	+	27869803	HPAFII	viability after 15 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.12438321891314841	[360]	[544,346,NaN]	1	hSpCas9	negative selection	9642028
21284959	21284982	17	-	27869803	ASPC1	viability after 36 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-1.0233057099716807	[434]	[92,65,67]	-7	hSpCas9	negative selection	9724472
21295690	21295713	17	+	27869803	ASPC1	viability after 36 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	0.19970498718635066	[394]	[322,179,23]	2	hSpCas9	negative selection	9724473
21295740	21295763	17	-	27869803	ASPC1	viability after 36 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.4004495948268598	[393]	[0,158,131]	-4	hSpCas9	negative selection	9724474
21298881	21298904	17	-	27869803	ASPC1	viability after 36 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.3232408338932925	[688]	[699,88,185]	3	hSpCas9	negative selection	9724475
21302181	21302204	17	+	27869803	ASPC1	viability after 36 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.8278837158156729	[476]	[89,72,111]	-7	hSpCas9	negative selection	9724476
21303213	21303236	17	+	27869803	ASPC1	viability after 36 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.9734249756649418	[1126]	[209,268,136]	-7	hSpCas9	negative selection	9724477
21284959	21284982	17	-	27869803	PATU8988S	viability after 35 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.5228130296549119	[383]	[310,132,NaN]	6	hSpCas9	negative selection	9806921
21295690	21295713	17	+	27869803	PATU8988S	viability after 35 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	0.2857701364358333	[346]	[112,227,NaN]	3	hSpCas9	negative selection	9806922
21295740	21295763	17	-	27869803	PATU8988S	viability after 35 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.35196328056978343	[189]	[40,78,NaN]	-4	hSpCas9	negative selection	9806923
21298881	21298904	17	-	27869803	PATU8988S	viability after 35 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.1747338036650372	[531]	[111,267,NaN]	-2	hSpCas9	negative selection	9806924
21302181	21302204	17	+	27869803	PATU8988S	viability after 35 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	0.507718196543047	[441]	[78,427,NaN]	5	hSpCas9	negative selection	9806925
21303213	21303236	17	+	27869803	PATU8988S	viability after 35 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.6021096914899223	[1041]	[263,288,NaN]	-6	hSpCas9	negative selection	9806926
21284959	21284982	17	-	27869803	PATU8988S	viability after 31 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	0.8003002339242953	[383]	[307,213,NaN]	8	hSpCas9	negative selection	9889370
21295690	21295713	17	+	27869803	PATU8988S	viability after 31 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	0.08926030574739174	[346]	[122,177,NaN]	1	hSpCas9	negative selection	9889371
21295740	21295763	17	-	27869803	PATU8988S	viability after 31 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	0.09928597030608288	[189]	[74,88,NaN]	1	hSpCas9	negative selection	9889372
21298881	21298904	17	-	27869803	PATU8988S	viability after 31 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	-0.5807970213343008	[531]	[92,203,NaN]	-6	hSpCas9	negative selection	9889373
21302181	21302204	17	+	27869803	PATU8988S	viability after 31 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	0.10179333699726531	[441]	[39,378,NaN]	1	hSpCas9	negative selection	9889374
21303213	21303236	17	+	27869803	PATU8988S	viability after 31 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.5394417335347823	[1041]	[251,328,NaN]	-5	hSpCas9	negative selection	9889375
21284959	21284982	17	-	27869803	HPAFII	viability after 35 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-1.6095354931979737	[144]	[16,31,NaN]	-7	hSpCas9	negative selection	9971819
21295690	21295713	17	+	27869803	HPAFII	viability after 35 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-2.2473539670969807	[159]	[17,15,NaN]	-8	hSpCas9	negative selection	9971820
21295740	21295763	17	-	27869803	HPAFII	viability after 35 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.8471398100791407	[100]	[50,2,NaN]	-5	hSpCas9	negative selection	9971821
21298881	21298904	17	-	27869803	HPAFII	viability after 35 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.004341032949020385	[177]	[32,154,NaN]	0	hSpCas9	negative selection	9971822
21302181	21302204	17	+	27869803	HPAFII	viability after 35 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-1.8584332329961284	[195]	[48,2,NaN]	-7	hSpCas9	negative selection	9971823
21303213	21303236	17	+	27869803	HPAFII	viability after 35 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.8248320447535608	[360]	[97,108,NaN]	-5	hSpCas9	negative selection	9971824
21284959	21284982	17	-	27869803	HPAFII	viability after 31 days	GGGAGCGCCTACCTTTGGACTGG	MAP2K3	ENSG00000034152	-0.3888554041745541	[144]	[31,94,NaN]	-3	hSpCas9	negative selection	10054268
21295690	21295713	17	+	27869803	HPAFII	viability after 31 days	GGCCAGTCCATATACCACCCAGG	MAP2K3	ENSG00000034152	-2.1989331808991714	[159]	[31,5,NaN]	-8	hSpCas9	negative selection	10054269
21295740	21295763	17	-	27869803	HPAFII	viability after 31 days	GGGCACTTGCACATATGGGCTGG	MAP2K3	ENSG00000034152	-0.4271350945894963	[100]	[67,13,NaN]	-3	hSpCas9	negative selection	10054270
21298881	21298904	17	-	27869803	HPAFII	viability after 31 days	TCCGGGAGTCCAGGTTCCGGGGG	MAP2K3	ENSG00000034152	0.04413829589207818	[177]	[35,175,NaN]	0	hSpCas9	negative selection	10054271
21302181	21302204	17	+	27869803	HPAFII	viability after 31 days	CTTGGACAAGTTCTACCGGAAGG	MAP2K3	ENSG00000034152	-0.34052878719686175	[195]	[150,16,NaN]	-2	hSpCas9	negative selection	10054272
21303213	21303236	17	+	27869803	HPAFII	viability after 31 days	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.7680991105951662	[360]	[173,58,NaN]	-5	hSpCas9	negative selection	10054273
21300589	21300612	17	+	28162770	P31FUJ	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-0.16568800855584165	[83]	[87]	-2	hSpCas9	negative selection	10188667
21298464	21298487	17	-	28162770	P31FUJ	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.5168744415013816	[225]	[379]	6	hSpCas9	negative selection	10188668
21300884	21300907	17	-	28162770	P31FUJ	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.7219211514266922	[312]	[222]	-5	hSpCas9	negative selection	10188669
21312192	21312215	17	+	28162770	P31FUJ	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	0.044038000944445654	[103]	[125]	0	hSpCas9	negative selection	10188670
21300617	21300640	17	+	28162770	P31FUJ	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.0361674817779114	[282]	[340]	0	hSpCas9	negative selection	10188671
21302238	21302261	17	-	28162770	P31FUJ	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.07879875231108868	[700]	[869]	0	hSpCas9	negative selection	10188672
21303213	21303236	17	+	28162770	P31FUJ	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.3302543934965978	[552]	[816]	3	hSpCas9	negative selection	10188673
21304439	21304462	17	+	28162770	P31FUJ	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.04730571477835675	[195]	[237]	0	hSpCas9	negative selection	10188674
21305107	21305130	17	+	28162770	P31FUJ	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-2.6437353053604857	[116]	[21]	-9	hSpCas9	negative selection	10188675
21312252	21312275	17	-	28162770	P31FUJ	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-1.3873121534700035	[511]	[229]	-7	hSpCas9	negative selection	10188676
21300589	21300612	17	+	28162770	TF1	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[2]	1	hSpCas9	negative selection	10358033
21298464	21298487	17	-	28162770	TF1	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[273]	1	hSpCas9	negative selection	10358034
21300884	21300907	17	-	28162770	TF1	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[143]	1	hSpCas9	negative selection	10358035
21312192	21312215	17	+	28162770	TF1	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[1]	1	hSpCas9	negative selection	10358036
21300617	21300640	17	+	28162770	TF1	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[203]	1	hSpCas9	negative selection	10358037
21302238	21302261	17	-	28162770	TF1	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[263]	1	hSpCas9	negative selection	10358038
21303213	21303236	17	+	28162770	TF1	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[205]	1	hSpCas9	negative selection	10358039
21304439	21304462	17	+	28162770	TF1	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[19]	1	hSpCas9	negative selection	10358040
21305107	21305130	17	+	28162770	TF1	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[3]	1	hSpCas9	negative selection	10358041
21312252	21312275	17	-	28162770	TF1	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	NaN	[NaN]	[144]	1	hSpCas9	negative selection	10358042
21300589	21300612	17	+	28162770	SKM1	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	0.14998392580839792	[25]	[50]	1	hSpCas9	negative selection	10527399
21298464	21298487	17	-	28162770	SKM1	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.9361803820538965	[80]	[273]	8	hSpCas9	negative selection	10527400
21300884	21300907	17	-	28162770	SKM1	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.6540570607079339	[80]	[90]	-5	hSpCas9	negative selection	10527401
21312192	21312215	17	+	28162770	SKM1	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-0.21628063713405177	[22]	[34]	-2	hSpCas9	negative selection	10527402
21300617	21300640	17	+	28162770	SKM1	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.6573506147385519	[84]	[236]	6	hSpCas9	negative selection	10527403
21302238	21302261	17	-	28162770	SKM1	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-0.5650933949850534	[235]	[281]	-4	hSpCas9	negative selection	10527404
21303213	21303236	17	+	28162770	SKM1	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.0700156211049826	[103]	[192]	0	hSpCas9	negative selection	10527405
21304439	21304462	17	+	28162770	SKM1	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.31126483284145856	[30]	[67]	3	hSpCas9	negative selection	10527406
21305107	21305130	17	+	28162770	SKM1	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-0.30742852519224706	[20]	[29]	-3	hSpCas9	negative selection	10527407
21312252	21312275	17	-	28162770	SKM1	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	0.40861123011941086	[74]	[175]	4	hSpCas9	negative selection	10527408
21300589	21300612	17	+	28162770	SKM1	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	0.14998392580839792	[25]	[50]	1	hSpCas9	negative selection	10696765
21298464	21298487	17	-	28162770	SKM1	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.9361803820538965	[80]	[273]	8	hSpCas9	negative selection	10696766
21300884	21300907	17	-	28162770	SKM1	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.6540570607079339	[80]	[90]	-5	hSpCas9	negative selection	10696767
21312192	21312215	17	+	28162770	SKM1	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-0.21628063713405177	[22]	[34]	-2	hSpCas9	negative selection	10696768
21300617	21300640	17	+	28162770	SKM1	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.6573506147385519	[84]	[236]	6	hSpCas9	negative selection	10696769
21302238	21302261	17	-	28162770	SKM1	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-0.5650933949850534	[235]	[281]	-4	hSpCas9	negative selection	10696770
21303213	21303236	17	+	28162770	SKM1	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.0700156211049826	[103]	[192]	0	hSpCas9	negative selection	10696771
21304439	21304462	17	+	28162770	SKM1	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.31126483284145856	[30]	[67]	3	hSpCas9	negative selection	10696772
21305107	21305130	17	+	28162770	SKM1	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-0.30742852519224706	[20]	[29]	-3	hSpCas9	negative selection	10696773
21312252	21312275	17	-	28162770	SKM1	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	0.40861123011941086	[74]	[175]	4	hSpCas9	negative selection	10696774
21300589	21300612	17	+	28162770	PL21	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-0.7540566958975552	[123]	[31]	-5	hSpCas9	negative selection	10866131
21298464	21298487	17	-	28162770	PL21	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.716154761492985	[199]	[142]	6	hSpCas9	negative selection	10866132
21300884	21300907	17	-	28162770	PL21	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.2505217945202452	[245]	[89]	-2	hSpCas9	negative selection	10866133
21312192	21312215	17	+	28162770	PL21	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	0.6891776952119407	[113]	[79]	6	hSpCas9	negative selection	10866134
21300617	21300640	17	+	28162770	PL21	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	-0.6784222580607041	[352]	[95]	-5	hSpCas9	negative selection	10866135
21302238	21302261	17	-	28162770	PL21	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-0.18233002233309303	[1021]	[391]	-1	hSpCas9	negative selection	10866136
21303213	21303236	17	+	28162770	PL21	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.07640424606707541	[291]	[133]	0	hSpCas9	negative selection	10866137
21304439	21304462	17	+	28162770	PL21	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.5654240785710645	[117]	[75]	5	hSpCas9	negative selection	10866138
21305107	21305130	17	+	28162770	PL21	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-0.597367521611937	[72]	[20]	-4	hSpCas9	negative selection	10866139
21312252	21312275	17	-	28162770	PL21	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	0.5230589117797324	[290]	[181]	4	hSpCas9	negative selection	10866140
21300589	21300612	17	+	28162770	P31FUJ	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-0.16568800855584165	[83]	[87]	-2	hSpCas9	negative selection	11035497
21298464	21298487	17	-	28162770	P31FUJ	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.5168744415013816	[225]	[379]	6	hSpCas9	negative selection	11035498
21300884	21300907	17	-	28162770	P31FUJ	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.7219211514266922	[312]	[222]	-5	hSpCas9	negative selection	11035499
21312192	21312215	17	+	28162770	P31FUJ	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	0.044038000944445654	[103]	[125]	0	hSpCas9	negative selection	11035500
21300617	21300640	17	+	28162770	P31FUJ	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.0361674817779114	[282]	[340]	0	hSpCas9	negative selection	11035501
21302238	21302261	17	-	28162770	P31FUJ	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.07879875231108868	[700]	[869]	0	hSpCas9	negative selection	11035502
21303213	21303236	17	+	28162770	P31FUJ	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.3302543934965978	[552]	[816]	3	hSpCas9	negative selection	11035503
21304439	21304462	17	+	28162770	P31FUJ	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.04730571477835675	[195]	[237]	0	hSpCas9	negative selection	11035504
21305107	21305130	17	+	28162770	P31FUJ	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-2.6437353053604857	[116]	[21]	-9	hSpCas9	negative selection	11035505
21312252	21312275	17	-	28162770	P31FUJ	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-1.3873121534700035	[511]	[229]	-7	hSpCas9	negative selection	11035506
21300589	21300612	17	+	28162770	OCIAML5	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-5.278331325566095	[42]	[1]	-9	hSpCas9	negative selection	11204863
21298464	21298487	17	-	28162770	OCIAML5	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.667071293897568	[141]	[406]	6	hSpCas9	negative selection	11204864
21300884	21300907	17	-	28162770	OCIAML5	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.551893028617156	[146]	[180]	-4	hSpCas9	negative selection	11204865
21312192	21312215	17	+	28162770	OCIAML5	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-0.38909459452145123	[36]	[50]	-3	hSpCas9	negative selection	11204866
21300617	21300640	17	+	28162770	OCIAML5	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.42327473042140984	[213]	[517]	3	hSpCas9	negative selection	11204867
21302238	21302261	17	-	28162770	OCIAML5	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.20777283768649113	[365]	[762]	1	hSpCas9	negative selection	11204868
21303213	21303236	17	+	28162770	OCIAML5	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.2440488339151753	[268]	[409]	-2	hSpCas9	negative selection	11204869
21304439	21304462	17	+	28162770	OCIAML5	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.4909671570350167	[94]	[240]	4	hSpCas9	negative selection	11204870
21305107	21305130	17	+	28162770	OCIAML5	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-4.693368824844939	[42]	[2]	-9	hSpCas9	negative selection	11204871
21312252	21312275	17	-	28162770	OCIAML5	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.11864568374120316	[162]	[270]	-1	hSpCas9	negative selection	11204872
21300589	21300612	17	+	28162770	EOL1	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-2.284905594058415	[147]	[15]	-8	hSpCas9	negative selection	11374229
21298464	21298487	17	-	28162770	EOL1	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.22963680423149205	[292]	[180]	2	hSpCas9	negative selection	11374230
21300884	21300907	17	-	28162770	EOL1	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	0.08066697348781637	[419]	[233]	0	hSpCas9	negative selection	11374231
21312192	21312215	17	+	28162770	EOL1	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	0.420384381818707	[216]	[152]	4	hSpCas9	negative selection	11374232
21300617	21300640	17	+	28162770	EOL1	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.390034293536736	[561]	[387]	3	hSpCas9	negative selection	11374233
21302238	21302261	17	-	28162770	EOL1	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.22830420268179363	[1501]	[926]	2	hSpCas9	negative selection	11374234
21303213	21303236	17	+	28162770	EOL1	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.2321947143615516	[466]	[288]	2	hSpCas9	negative selection	11374235
21304439	21304462	17	+	28162770	EOL1	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.09553396838315742	[150]	[84]	0	hSpCas9	negative selection	11374236
21305107	21305130	17	+	28162770	EOL1	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-2.44891062395691	[113]	[10]	-8	hSpCas9	negative selection	11374237
21312252	21312275	17	-	28162770	EOL1	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.21747123330189325	[383]	[173]	-2	hSpCas9	negative selection	11374238
21300589	21300612	17	+	28162770	MOLM13	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-1.1725682317682808	[105]	[33]	-6	hSpCas9	negative selection	11543595
21298464	21298487	17	-	28162770	MOLM13	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.8183866286287121	[279]	[356]	6	hSpCas9	negative selection	11543596
21300884	21300907	17	-	28162770	MOLM13	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.29019563885415456	[366]	[216]	-2	hSpCas9	negative selection	11543597
21312192	21312215	17	+	28162770	MOLM13	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	0.721645973790362	[129]	[154]	5	hSpCas9	negative selection	11543598
21300617	21300640	17	+	28162770	MOLM13	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.7741358541996715	[443]	[548]	6	hSpCas9	negative selection	11543599
21302238	21302261	17	-	28162770	MOLM13	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.18280886968352705	[1120]	[919]	1	hSpCas9	negative selection	11543600
21303213	21303236	17	+	28162770	MOLM13	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.10523150653206081	[545]	[366]	0	hSpCas9	negative selection	11543601
21304439	21304462	17	+	28162770	MOLM13	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-0.19554717719966208	[254]	[160]	-1	hSpCas9	negative selection	11543602
21305107	21305130	17	+	28162770	MOLM13	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-3.397181038369313	[101]	[6]	-8	hSpCas9	negative selection	11543603
21312252	21312275	17	-	28162770	MOLM13	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-1.7997115509534267	[442]	[91]	-7	hSpCas9	negative selection	11543604
21300589	21300612	17	+	28162770	HEL	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-3.1121486701631116	[107]	[7]	-9	hSpCas9	negative selection	11712961
21298464	21298487	17	-	28162770	HEL	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	1.2431313732911193	[247]	[375]	9	hSpCas9	negative selection	11712962
21300884	21300907	17	-	28162770	HEL	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	0.40696738086270917	[324]	[275]	3	hSpCas9	negative selection	11712963
21312192	21312215	17	+	28162770	HEL	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-0.7061563104872748	[134]	[52]	-4	hSpCas9	negative selection	11712964
21300617	21300640	17	+	28162770	HEL	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.186134839995869	[445]	[324]	1	hSpCas9	negative selection	11712965
21302238	21302261	17	-	28162770	HEL	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-0.493161103172967	[1078]	[490]	-3	hSpCas9	negative selection	11712966
21303213	21303236	17	+	28162770	HEL	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-1.093251638748605	[492]	[147]	-6	hSpCas9	negative selection	11712967
21304439	21304462	17	+	28162770	HEL	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-1.3510292142881286	[230]	[57]	-7	hSpCas9	negative selection	11712968
21305107	21305130	17	+	28162770	HEL	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-2.693544555864076	[100]	[9]	-8	hSpCas9	negative selection	11712969
21312252	21312275	17	-	28162770	HEL	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.137816030713532	[279]	[162]	-1	hSpCas9	negative selection	11712970
21300589	21300612	17	+	28162770	MV411	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-3.3545984632973225	[84]	[6]	-9	hSpCas9	negative selection	11882327
21298464	21298487	17	-	28162770	MV411	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	-0.21535307994443675	[214]	[155]	-2	hSpCas9	negative selection	11882328
21300884	21300907	17	-	28162770	MV411	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.08338694459298307	[243]	[193]	0	hSpCas9	negative selection	11882329
21312192	21312215	17	+	28162770	MV411	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-1.7208535894898869	[89]	[22]	-8	hSpCas9	negative selection	11882330
21300617	21300640	17	+	28162770	MV411	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.6961343614128506	[232]	[317]	6	hSpCas9	negative selection	11882331
21302238	21302261	17	-	28162770	MV411	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-0.048866228765973574	[850]	[692]	0	hSpCas9	negative selection	11882332
21303213	21303236	17	+	28162770	MV411	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.2898035815882988	[301]	[310]	2	hSpCas9	negative selection	11882333
21304439	21304462	17	+	28162770	MV411	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	0.8907440377347364	[104]	[163]	7	hSpCas9	negative selection	11882334
21305107	21305130	17	+	28162770	MV411	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-1.3105579023381113	[52]	[17]	-7	hSpCas9	negative selection	11882335
21312252	21312275	17	-	28162770	MV411	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.48417480888922404	[268]	[161]	-4	hSpCas9	negative selection	11882336
21300589	21300612	17	+	28162770	MONOMAC1	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	0.5092319498837359	[37]	[61]	5	hSpCas9	negative selection	12051693
21298464	21298487	17	-	28162770	MONOMAC1	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.016477422930441465	[162]	[188]	0	hSpCas9	negative selection	12051694
21300884	21300907	17	-	28162770	MONOMAC1	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	-0.13882223311425806	[169]	[176]	-1	hSpCas9	negative selection	12051695
21312192	21312215	17	+	28162770	MONOMAC1	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-0.39295705703481054	[62]	[54]	-3	hSpCas9	negative selection	12051696
21300617	21300640	17	+	28162770	MONOMAC1	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	1.7942459358393374	[165]	[659]	9	hSpCas9	negative selection	12051697
21302238	21302261	17	-	28162770	MONOMAC1	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.14182164377768602	[592]	[749]	1	hSpCas9	negative selection	12051698
21303213	21303236	17	+	28162770	MONOMAC1	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	0.2567896467339402	[210]	[288]	2	hSpCas9	negative selection	12051699
21304439	21304462	17	+	28162770	MONOMAC1	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-0.7550323001804407	[105]	[71]	-6	hSpCas9	negative selection	12051700
21305107	21305130	17	+	28162770	MONOMAC1	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-2.4865434642545385	[43]	[8]	-9	hSpCas9	negative selection	12051701
21312252	21312275	17	-	28162770	MONOMAC1	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	0.7638633332515061	[186]	[363]	7	hSpCas9	negative selection	12051702
21300589	21300612	17	+	28162770	OCIAML2	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-1.4420606730453902	[24]	[50]	-7	hSpCas9	negative selection	12221059
21298464	21298487	17	-	28162770	OCIAML2	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	0.9396541440660483	[37]	[403]	8	hSpCas9	negative selection	12221060
21300884	21300907	17	-	28162770	OCIAML2	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	0.12474929142433339	[45]	[277]	1	hSpCas9	negative selection	12221061
21312192	21312215	17	+	28162770	OCIAML2	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	0.1001188162592942	[16]	[100]	0	hSpCas9	negative selection	12221062
21300617	21300640	17	+	28162770	OCIAML2	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	0.5456719870869391	[54]	[444]	5	hSpCas9	negative selection	12221063
21302238	21302261	17	-	28162770	OCIAML2	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	0.02365335288858761	[144]	[816]	0	hSpCas9	negative selection	12221064
21303213	21303236	17	+	28162770	OCIAML2	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.3960828718771071	[65]	[277]	-3	hSpCas9	negative selection	12221065
21304439	21304462	17	+	28162770	OCIAML2	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-0.08158753449626188	[20]	[109]	0	hSpCas9	negative selection	12221066
21305107	21305130	17	+	28162770	OCIAML2	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-1.4706298252421615	[12]	[25]	-7	hSpCas9	negative selection	12221067
21312252	21312275	17	-	28162770	OCIAML2	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.5961607073260201	[56]	[208]	-4	hSpCas9	negative selection	12221068
21300589	21300612	17	+	28162770	OCIAML3	viability	GGGCCGTGGAGCCTATGGGGTGG	MAP2K3	ENSG00000034152	-1.5940076403241632	[14]	[14]	-8	hSpCas9	negative selection	12390425
21298464	21298487	17	-	28162770	OCIAML3	viability	GACTCACGTGGGGTTGGGTGCGG	MAP2K3	ENSG00000034152	-0.06349292362538336	[62]	[181]	0	hSpCas9	negative selection	12390426
21300884	21300907	17	-	28162770	OCIAML3	viability	CTGCTCCTGTGAGTTCACGGTGG	MAP2K3	ENSG00000034152	0.33797393624718586	[75]	[289]	3	hSpCas9	negative selection	12390427
21312192	21312215	17	+	28162770	OCIAML3	viability	CCAGCAGCTGAAGCAGGTGGTGG	MAP2K3	ENSG00000034152	-2.0414666172953844	[29]	[21]	-8	hSpCas9	negative selection	12390428
21300617	21300640	17	+	28162770	OCIAML3	viability	AAGGTGCGGCACGCCCAGAGCGG	MAP2K3	ENSG00000034152	-0.11849628201900403	[72]	[202]	-1	hSpCas9	negative selection	12390429
21302238	21302261	17	-	28162770	OCIAML3	viability	CAGACACAGCAATCTCCCCAAGG	MAP2K3	ENSG00000034152	-0.18836883904756885	[230]	[611]	-1	hSpCas9	negative selection	12390430
21303213	21303236	17	+	28162770	OCIAML3	viability	AAGCTGTCGGTGATCCACAGAGG	MAP2K3	ENSG00000034152	-0.3248210075087742	[116]	[281]	-3	hSpCas9	negative selection	12390431
21304439	21304462	17	+	28162770	OCIAML3	viability	CAATGTCCTTATCAACAAGGAGG	MAP2K3	ENSG00000034152	-0.3626820942177075	[45]	[107]	-3	hSpCas9	negative selection	12390432
21305107	21305130	17	+	28162770	OCIAML3	viability	CTGGAGCCTGGGCATCACCATGG	MAP2K3	ENSG00000034152	-2.8164000616606115	[13]	[5]	-9	hSpCas9	negative selection	12390433
21312252	21312275	17	-	28162770	OCIAML3	viability	CAGTGAAGTCCACAAACTCGGGG	MAP2K3	ENSG00000034152	-0.47315324544977755	[102]	[223]	-4	hSpCas9	negative selection	12390434